ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7167 check: MH O KOG0961 Posttranslational modification, protein turnover, chaperones Predicted Zn2+-dependent endopeptidase, insulinase superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7167 2499894 2496784 -1037
(1037 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL098c [O] KOG0961 Predicted Zn2+-dependent endopeptidase insul... 1090 0.0
SPAC3H1.02c [O] KOG0961 Predicted Zn2+-dependent endopeptidase i... 373 e-103
CE03926 [O] KOG0961 Predicted Zn2+-dependent endopeptidase insul... 332 2e-90
At1g49630 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase supe... 122 4e-27
At3g19170 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase supe... 121 6e-27
Hs7657343 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase supe... 120 8e-27
SPBC119.17 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase sup... 112 2e-24
7302255 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase superf... 103 1e-21
YDR430c [RO] KOG2019 Metalloendoprotease HMP1 (insulinase superf... 83 3e-15
ECU06g0750 [O] KOG0959 N-arginine dibasic convertase NRD1 and re... 62 5e-09
7292708 [O] KOG0959 N-arginine dibasic convertase NRD1 and relat... 53 3e-06
At2g41790 [O] KOG0959 N-arginine dibasic convertase NRD1 and rel... 52 4e-06
7296294 [O] KOG0959 N-arginine dibasic convertase NRD1 and relat... 52 5e-06
>YOL098c [O] KOG0961 Predicted Zn2+-dependent endopeptidase insulinase
superfamily
Length = 1037
Score = 1090 bits (2819), Expect = 0.0
Identities = 536/1024 (52%), Positives = 716/1024 (69%), Gaps = 11/1024 (1%)
Query: 1 MTFKKLVSFEVEYAPQYHFTKYISTRTKLQLVHLNNKSSPLVQGYFAVGTECPTDSGVPH 60
M FKKLVSF+ +Y PQYH TKYIS RTKLQLVH+N+K+SPLV GYFAV TEC DSG PH
Sbjct: 1 MGFKKLVSFQPDYVPQYHITKYISERTKLQLVHINHKTSPLVHGYFAVPTECLNDSGAPH 60
Query: 61 TLEHLIFMGSEKYPYKGLLDTAGNLCMSNTNAWTATDQTVYTLSTAGWKGFKKLLPVYLD 120
TLEHLIFMGS+ YPYKGLLDTAGNL +SNTNAWT TDQTVYTLS+AGWKGF KLLP YLD
Sbjct: 61 TLEHLIFMGSKSYPYKGLLDTAGNLSLSNTNAWTDTDQTVYTLSSAGWKGFSKLLPAYLD 120
Query: 121 HLFFPTLTEDACTTEVYHIDPDDLSDKGVVFSEMAGIESQSWFITTLEKQRLLFPEGSGY 180
H+ PTLT++AC TEVYHIDP++L DKGVVFSEM IE+Q W+I+ LEKQRL+FPEGSGY
Sbjct: 121 HILHPTLTDEACLTEVYHIDPENLGDKGVVFSEMEAIETQGWYISGLEKQRLMFPEGSGY 180
Query: 181 RSETGGLTPNLRVLTNDEIREFHKQMYTPDNCCVIITGNIPSEELIELMEIFDKQLPEFT 240
RSETGGLT NLR LTNDEIR+FHK +Y+ DN CVI+ GN+P++EL+ +ME +D +LPE
Sbjct: 181 RSETGGLTKNLRTLTNDEIRQFHKSLYSSDNLCVIVCGNVPTDELLTVMEEWDNKLPEIP 240
Query: 241 AN-ERKRPFIDTPASQIPQSLTEMKEKTIEFPEADESQGEVSFSWITQPYLKHIEDQAVN 299
+N +KRPF+D S IPQS ++ E T+EFPE DESQGE+ FSWI PY D AV+
Sbjct: 241 SNIPKKRPFLDNKLSHIPQSRDKVTESTVEFPELDESQGELLFSWIGVPYSDFRNDLAVD 300
Query: 300 ILLEYLTESPLAPFNMEMIEIENPYATDAEYWSDDFIRTISNISLKGVPTDRLQQAKEKT 359
+LL+Y T+S LA F E++EI++P A + +D F+RTI ++ ++GVPT+++ K K
Sbjct: 301 VLLDYFTDSALAVFTRELVEIDDPMANSTDCCTDYFMRTIIDLRIQGVPTEKIAATKTKV 360
Query: 360 LDLLKTHHVSLDRIRLVTENMKWDYIFKFEKIGDTMVAHMAITDFLYGATDGGVLEESLK 419
L++LKTH + L R+R V EN KW+Y+ +EK G++ + ITD++YG DG L SLK
Sbjct: 361 LEILKTHTIDLSRVRQVVENTKWEYLLNYEKNGESRFSSAVITDYIYGNEDGSSLVSSLK 420
Query: 420 TLEDFNILLSWSQEKWQALLEESFVTNQPVVVIGKPSSKLNEKLENENDSRMKERAKLFD 479
L DF+ LL WSQ+ WQ+LL FV N+P++V KPS+ + E+LE E +K+R FD
Sbjct: 421 DLSDFDALLQWSQKDWQSLLNRIFVDNKPIIVTAKPSALMYEQLEKEKSDLIKQREAEFD 480
Query: 480 DAKRKALKESLSQAQHNNNVQIPDDVLGSFEIENPQDSVYFTETKSISCI-PVPSNDSDF 538
D K+ L + L+ A++ N+ IP +L FEI+NP SV F TKSI+ + N+
Sbjct: 481 DEKKLVLLKRLNNAKNINDRPIPKSLLQKFEIDNPSKSVEFVNTKSIATVDSYKYNNVSD 540
Query: 539 PLTDNIINLKPKAFPFFIHFEHFPSQFVEIHVALNVDFVKDCELLPYYHVVTELFSMPM- 597
PLT I+ +P FP FIH HFPSQF+E+H +N +KD LLPY+++ ELFSMPM
Sbjct: 541 PLTKKILETRPDNFPLFIHLNHFPSQFIELHFLVNSASIKDTSLLPYFNMFDELFSMPMK 600
Query: 598 ---IGENGET-ISFEDVVAQLKTETVETDISMGIGGNFSNLIDFKIQCKATNYSKAVNWL 653
N ET +SFE+VVA+LK+ET++ I+ G+ G+ +LI+FKIQC+A YS +V W+
Sbjct: 601 ILDEESNVETMLSFEEVVAKLKSETIDAQINQGLKGSCPDLINFKIQCRAGGYSNSVQWI 660
Query: 654 KRVLFDSVFDESRVSILLEKFYNSIVETKREGDQMMFSSMNRHLYNEGSLKKSADELYVE 713
K LFD VFDE+RV ILLE + NSIVE KR G+ M+ S NR+LY+ SLKKS D L+VE
Sbjct: 661 KHCLFDMVFDENRVRILLENYLNSIVEWKRNGNVMLSSLTNRNLYSARSLKKSTDPLFVE 720
Query: 714 PIIESVLTDIEDGHYIQKILPKLESLRTQLTEQLHKAHILVFGDIDRLGDIYEPWSRYFA 773
++ + +IE+G++ ++ILP++E++R QL +K HILV GDI ++ D+YEPW+
Sbjct: 721 AKLQEIFAEIENGNFEKEILPRIETMRKQLRANFNKFHILVLGDISKIDDVYEPWNPLI- 779
Query: 774 PKAKNIXXXXXXXXX--XXXXXXXXXEVGKNPIKKAFIVSTPASESSYMLALTALPGDLH 831
K NI + + P +KAFI++TPASES+YM +T++P +L
Sbjct: 780 -KCLNIAHPVEKLKIPPVPRALDTISSICRTPGEKAFIITTPASESAYMNLITSIPFNLD 838
Query: 832 YLHPDFPAIYLAAVYLECVEGPFWKGIRGAGLAYGAYLTKMFESNMVGFNVYRASDAVAC 891
Y P++ + LA+ YLECVEGPFWKGIRGAGLAYGA + K+ E N GFN+YR +D + C
Sbjct: 839 YHDPEYAIVSLASEYLECVEGPFWKGIRGAGLAYGASMLKLCEINSWGFNIYRGADIIKC 898
Query: 892 YEAGKQIVTDYAGGEKIFEPILIKXXXXXXXXXXXXXXXXYFNVAINKYLNTFCKKRGPD 951
YE GKQIV DYA G F+ LI+ YF A++KY++ FC +RG +
Sbjct: 899 YEVGKQIVQDYASGALEFDEQLIQGAISSIINRLATIECGYFETALSKYVDEFCLQRGNN 958
Query: 952 FNTEILKKLEKVTADDLKNAMTDVYIKIFDPARGSIFVACHPSKVESIHKYFESLSYDIT 1011
FN L++L+ VT DLKNAM ++ +FD + FV+CHP+K+ES+ ++FE+ + +
Sbjct: 959 FNELYLERLQNVTKTDLKNAMQKYFVNMFDSNKSVAFVSCHPAKLESVQEFFETQGFTVE 1018
Query: 1012 VEEI 1015
+EE+
Sbjct: 1019 IEEL 1022
>SPAC3H1.02c [O] KOG0961 Predicted Zn2+-dependent endopeptidase insulinase
superfamily
Length = 1036
Score = 373 bits (957), Expect = e-103
Identities = 265/1016 (26%), Positives = 469/1016 (46%), Gaps = 37/1016 (3%)
Query: 17 YHFTKYISTRTKLQLVHLNNKSSPLVQGYFAVGTECPTDSGVPHTLEHLIFMGSEKYPYK 76
Y K+I+ T + + +S L QG F V TE + G PHTLEHL FMGS+KYP
Sbjct: 19 YTVNKWINDATGFSVASVKTPTSRL-QGSFVVATEAHDNLGCPHTLEHLCFMGSKKYPMN 77
Query: 77 GLLDTAGNLCMSNTNAWTATDQTVYTLSTAGWKGFKKLLPVYLDHLFFPTLTEDACTTEV 136
G+L + NA T D T Y LS A GF +LLPV+ DH+ P L+++A TEV
Sbjct: 78 GILTKFAGRACGDINACTDVDYTSYELSAAEEDGFLRLLPVFADHILSPILSDEAFCTEV 137
Query: 137 YHIDPDDLSDKGVVFSEMAGIESQSWFITTLEKQRLLFPEGSGYRSETGGLTPNLRVLTN 196
YHI+ + GVV+SEM +S + + +P SGY ETGG LR L+
Sbjct: 138 YHINGMG-EESGVVYSEMQNTQSSETDVMFDCMRTSQYPVTSGYYYETGGHPSELRKLSI 196
Query: 197 DEIREFHKQMYTPDNCCVIITGNIPSEELIELMEIFDKQLPE---FTANERKRPFIDTPA 253
++IRE+HK+MY P N C+I+TG I L+ K++ T RP+ T
Sbjct: 197 EKIREYHKEMYVPSNICLIVTGCINESRLLSCASGIVKEILANGIITPPTWTRPWCST-- 254
Query: 254 SQIPQSLTEMKEKTIEFPEADESQGEVSFSWITQPYLKHIEDQAVNILLEYLTESPLAPF 313
+ ++ E KT++F DE G VS +W L A+ L E+L+ES ++PF
Sbjct: 255 -NVDYTIPEPILKTVKFSSEDEYTGSVSLAWNGPSALDAYTVFAIETLCEFLSESAVSPF 313
Query: 314 NMEMIEIENPYATDAEYWSDDFIRTISNISLKGVPTDRLQQAKEKTLDLL-KTHHVSLDR 372
+EIE+P+ + ++ + + VP +++ +++ L LL +T + ++R
Sbjct: 314 GQTFVEIEDPFCSFVYFYVSLRVPCSIQLFFDSVPLEKINGLEQRALRLLAETKQIDMNR 373
Query: 373 IRLVTENMKWDYIFKFEKIGDTMVAHMAITDFLYGATDGGVLEESLKTLEDFNILLSWSQ 432
++ + + Y+ E ++ + D +YG+ +G L LK LE +L W +
Sbjct: 374 MKDYLKTRRDQYLTNLEAFPSSLFMKILTLDHVYGSREGKDLPNLLKMLEYNRLLEEWEE 433
Query: 433 EKWQALLEESFVTNQPVVVIGKPSSKLNEKLENENDSRMKERAKLFDDAKRKALKESLSQ 492
+ W LL++ FV N V VI PS ++ E ++ EN ++ +R L + + L E L +
Sbjct: 434 KDWLKLLKKWFVENNSVTVIALPSFEMAENIKKENAEQLNKRRCLLGASGLEKLAEKLKK 493
Query: 493 AQHNNNVQIPDDVLGSFEIENPQDSVYFTET--KSISCIPVPSNDSDFPLTDNIINLKPK 550
++ N ++ +++ SF I +P+ +++ T ++ S N+ + ++ + P
Sbjct: 494 SKEKNEQKLSVNLISSFRISDPESIRFYSSTTARTRSAGQPFDNEVQTYIDTDVSSENP- 552
Query: 551 AFPFFIHFEHFPSQFVEIHVALNVDFVKDCELLPYYHVVTE-LFSMPMIGENGETISFED 609
FI F+H S FV++ ++ + L PY V + + + P + + +
Sbjct: 553 ----FIQFDHIDSSFVQLATYIDTSMIPS-SLKPYLSVFAKYIEAAPALLSGTIPTPYHE 607
Query: 610 VVAQLKTETVETDISMGIGGNF---------SNLIDFKIQCKATNYSKAVNWLKRVLFDS 660
VV QL+ +TV ++S+ + L+ +I+ NY K V W++ +L +
Sbjct: 608 VVKQLERDTVSLNVSLSFDTSSCGYAYYETKRELLSIEIKVTRENYEKGVYWIRNLLAKT 667
Query: 661 VFDESRVSILLEKFYNSIVETKREGDQMMFSSMNRHLYNEGSLKKSADELYVEPIIESVL 720
V+D R+ ++ + I KR+ + ++ S + LYN+ SLK S + L E I+ +
Sbjct: 668 VWDRERMLSVINQQLADIPFQKRDAEFILPSYFDIRLYNDCSLKYSLNTLSQEKILRELR 727
Query: 721 TDIEDGHYIQKILPKLESLRTQLTEQLHKA-HILVFGDIDRLGDIYEPWSRYFAPKAKNI 779
+++ H I + +R + + H+A I V GDI +L W++ +
Sbjct: 728 DKLQNDH--SSIFDAFQKMRNYMLQ--HQAIRIHVIGDILKLPQPISTWNKLLDSECHR- 782
Query: 780 XXXXXXXXXXXXXXXXXXEVGKNPIKKAFIVSTPASESSYMLALTALPGDLHYLHPDFPA 839
E G + ++ P++ESS + + ++PG +L P P
Sbjct: 783 NPNMEFLSTFSKNYLKPQEFGSS--SSLTVIPMPSNESSDL--VFSIPGITSWLDPSLPV 838
Query: 840 IYLAAVYLECVEGPFWKGIRGAGLAYGAYLTKMFESNMVGFNVYRASDAVACYEAGKQIV 899
I L A YL ++GPFW IRG+GLAYG ++ + ++ + + + D + + + +V
Sbjct: 839 IVLIANYLGLMDGPFWNTIRGSGLAYGFNMSIDVDGGVLYYCINTSPDVYKAWASSRDLV 898
Query: 900 TDYAGGEKIFEPILIKXXXXXXXXXXXXXXXXYFNVAINKYLNTFCKKRGPDFNTEILKK 959
GE ++ + N + K D + + L+K
Sbjct: 899 KSLISGEVQVSSFDLESAKCVSYSIVSELENNAIYSSKNSFTLLSIKGLNKDEDHKFLEK 958
Query: 960 LEKVTADDLKNAMTDVYIKIFDPARGSIFVACHPSKVESIHKYFESLSYDITVEEI 1015
+++VT + + F + + +K+E + F +++ VE +
Sbjct: 959 VKQVTLQQFLEGLKIYCLPFFSSSNNLAVITSSLAKIEQTVEQFTEEGFNVNVESL 1014
>CE03926 [O] KOG0961 Predicted Zn2+-dependent endopeptidase insulinase
superfamily
Length = 995
Score = 332 bits (850), Expect = 2e-90
Identities = 258/1007 (25%), Positives = 447/1007 (43%), Gaps = 66/1007 (6%)
Query: 22 YISTRTKLQLVHLNNKSSPLVQGYFAVGTECPTDSGVPHTLEHLIFMGSEKYPYKGLLDT 81
Y S TKL+ V + P+V G + TE +D G+PHTLEHL+FMGS+KYP+KG+LD
Sbjct: 23 YSSKNTKLR-VAIGEVPGPMVHGAVSFVTEADSDDGLPHTLEHLVFMGSKKYPFKGVLDV 81
Query: 82 AGNLCMSN-TNAWTATDQTVYTLSTAGWKGFKKLLPVYLDHLFFPTLTEDACTTEVYHID 140
N C+++ TNAWT TD T YTLST G GF K+LPVY++HL P LT TEV+HI
Sbjct: 82 IANRCLADGTNAWTDTDHTAYTLSTVGSDGFLKVLPVYINHLLTPMLTASQFATEVHHIT 141
Query: 141 PDDLSDKGVVFSEMAGIESQSWFITTLEKQRLLFPEGSGYRSETGGLTPNLR-VLTNDEI 199
+ +D GVV+SEM ES+ I + + +++P + Y +TGG NLR T +++
Sbjct: 142 GEG-NDAGVVYSEMQDHESEMESIMDRKTKEVIYPPFNPYAVDTGGRLKNLRESCTLEKV 200
Query: 200 REFHKQMYTPDNCCVIITGNIPSEELIELMEIFDKQLPEFTANERKRPFIDTPASQIPQS 259
R++HK+ Y N V + G + ++++E+M + + + +PF +
Sbjct: 201 RDYHKKFYHLSNMVVTVCGMVDHDQVLEIMNNVENEHMSTVPDHFPKPF--------SFA 252
Query: 260 LTEMKEKT---IEFPEADESQGEVSFSWITQPYLKHIEDQAVNILLEYLTESPLAPFNME 316
L+++KE T +E P D S+G V +W ++++L +YL+ + +AP +
Sbjct: 253 LSDIKESTVHRVECPTDDASRGAVEVAWFAHSPSDLETHSSLHVLFDYLSNTSVAPLQKD 312
Query: 317 MIEIENPYATDAEYWSDDFIRTISNISLKGVPTDRLQQAKEKTLDLLKTHHV-----SLD 371
I +E+P A+ + + +R ++ GVP ++L + K D H+ ++
Sbjct: 313 FILLEDPLASSVSFHIAEGVRCDLRLNFAGVPVEKLDECAPKFFDKTVREHLEEANFDME 372
Query: 372 RIRLVTENMKWDYIFKFEKIGDTMVAHMAITDFLYGATDGGVLEESLKTLEDFNILLSWS 431
R+ + + + + K E + I L+ D + ++ ++ L S
Sbjct: 373 RMGYLIDQTILNELVKLETNAPKDIMSHIIGHQLFDNEDEELFKKRTNEIDFLKKLKSEP 432
Query: 432 QEKWQALLEESFVTNQPVVVIGKPSSKLNEKLENENDSRMKERAKLFDDAKRKALKESLS 491
W L+ + F T VIG P+ +L +K+ E + R+ + + + +SL
Sbjct: 433 ASYWVQLVNKYF-TAPSATVIGVPNEELVDKIAEEEEKRIAAQCEKLGKKGLEEAGKSLE 491
Query: 492 QAQHNNNVQIPDDVLGSFEIENPQDSVYFTETKSISCIPVPSNDSDFPLTDNIINLKPK- 550
A N P L D + + ++ PV S LT N +L P+
Sbjct: 492 AAILENTANHPSAEL--------LDQLIVKDLEAFDRFPVQS------LTSNSPSLTPQQ 537
Query: 551 -----AFPFFIHFEHFPSQFVEIHVALNVDFVKDCELLPYYHVVTELFSMPMIGENGETI 605
FPF + + P++FVEI L+ + E Y + T+L +G
Sbjct: 538 STFLAQFPFHANLHNCPTKFVEIFFLLDSSNL-SIEDRSYLFLYTDLLFESPAMIDGVLT 596
Query: 606 SFEDVVAQLKTETVETDISMGIGGNFSNLIDFKIQCKATNYSKAVNWLKRVLFDSVFDES 665
S +DV + ++ I +G+ G + ++ +I+ A Y W + VFD S
Sbjct: 597 SADDVAKHFTKDLIDHSIQVGVSGLYDRFVNLRIKVGADKYPLLAKWAQIFTQGVVFDPS 656
Query: 666 RVSILLEKFYNSIVETKREGDQMMFSSMNRHLYNEGSLKKSADELYVEPIIESVLTDIED 725
R+ +K + KR+G + +++ +Y + + DEL +E + E + D+
Sbjct: 657 RIHQCAQKLAGEARDRKRDGCTVASTAVASMVYGKNTNCILFDELVLEKLHEKISKDVMK 716
Query: 726 GHYIQKILPKLESLRTQLTEQLHKAHILVFGDIDRLGDIYEPWSRYFAPK--AKNIXXXX 783
+ +L KLE +R+ L AH + D+D + PK + ++
Sbjct: 717 NP--EAVLEKLEQVRSALFSNGVNAHFV--ADVDSID-----------PKMLSSDLWTWV 761
Query: 784 XXXXXXXXXXXXXXEVGKN---PIKKAFIVSTPASESSYMLALTALPGDLHYLHPDFPAI 840
E G+N + K ++ SESS++ + L D ++ +
Sbjct: 762 QADPRFGPGHQFSAEAGENVSLELGKELLIGVGGSESSFIYQTSFL--DANWNSEELIPA 819
Query: 841 YLAAVYLECVEGPFWKGIRGAGLAYGAYLTKMFESNMVGFNVYRASDAVACYEAGKQIVT 900
+ YL EGP W+ IRG GLAYGA + + + ++YR + YE + I+
Sbjct: 820 MIFGQYLSQCEGPLWRAIRGDGLAYGANVFVKPDRKQITLSLYRCAQPAVAYERTRDIIR 879
Query: 901 DYAGGEKIFEPILIKXXXXXXXXXXXXXXXXYFNVAINKYLNTFCKKRGPDFNTEILKKL 960
+I + A LN F + P FN ++ +++
Sbjct: 880 KIVESGEI-SKAEFEGAKRSTVFEMMKREGTVSGAAKISILNNFRQTPHP-FNIDLCRRI 937
Query: 961 EKVTADDLKNAMTDVYIKIFDPARGSIFVACHPSKVESIHKYFESLS 1007
+T++++ ++FD +A HPSK+ + K F S
Sbjct: 938 WNLTSEEMVKIGGPPLARLFDEKCFVRSIAVHPSKLNEMKKAFPGSS 984
>At1g49630 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase superfamily)
Length = 1076
Score = 122 bits (305), Expect = 4e-27
Identities = 135/520 (25%), Positives = 227/520 (42%), Gaps = 44/520 (8%)
Query: 53 PTDS-GVPHTLEHLIFMGSEKYPYKG-LLDTAGNLCMSNTNAWTATDQTVYTLSTAGWKG 110
P DS G+PH LEH + GS KYP K ++ + NA+T D+T Y +++ K
Sbjct: 153 PKDSTGIPHILEHSVLCGSRKYPMKEPFVELLKGSLHTFLNAFTYPDRTCYPVASTNKKD 212
Query: 111 FKKLLPVYLDHLFFPTLTEDACT--TEVYHI---DP-DDLSDKGVVFSEMAGIESQSWFI 164
F L+ VYLD +FFP +D T E +H DP +D+S KGVVF+EM G+ SQ I
Sbjct: 213 FYNLVDVYLDAVFFPKCVDDVHTFQQEGWHYELNDPSEDISYKGVVFNEMKGVYSQPDNI 272
Query: 165 TTLEKQRLLFPEGSGYRSETGGLTPNLRVLTNDEIREFHKQMYTPDNCCVIITGNIPSEE 224
R L PE + Y ++GG ++ LT ++ +EFH+Q Y P N + G+ ++
Sbjct: 273 L----GRALCPENT-YGVDSGGDPKDIPKLTFEKFKEFHRQYYHPSNARIWFYGD---DD 324
Query: 225 LIELMEIFDKQLPEFTANERKRPFIDTPASQIPQSLTEMKEKTIE-FPEADE----SQGE 279
+ + + + L F A+ P D+ + PQ L + +E +P ++ +
Sbjct: 325 PVHRLRVLSEYLDMFDAS----PARDSSKVE-PQKLFSRPRRIVEKYPAGEDGDLKKKHM 379
Query: 280 VSFSWITQPYLKHIEDQ-AVNILLEYLTESPLAPFNMEMIEIENPYATDAEYWSDDFIRT 338
V +W+ ++ Q A+ L + +P +P ++E A D+ ++
Sbjct: 380 VCLNWLLSDKPLDLQTQLALGFLDHLMLGTPASPLRKILLESGLGEALVNSGMEDELLQP 439
Query: 339 ISNISLKGVPTDRLQQAKEKTLDLL-KTHHVSLDRIRLVTENMKWDYIFKFEKIGDT--- 394
+I LKGV D +Q+ +E ++ L K D + ++ + G +
Sbjct: 440 QFSIGLKGVSDDNVQKVEELVMNTLRKLADEGFDTDAVEASMNTIEFSLRENNTGSSPRG 499
Query: 395 -MVAHMAITDFLYGATDGGVL--EESLKTLEDFNILLSWSQEKWQALLEESFVTNQPVVV 451
+ +I ++Y L EE LK+L+ I S+ + L+EE + N V
Sbjct: 500 LSLMLQSIAKWIYDMDPFEPLKYEEPLKSLK-ARIAEKGSKSVFSPLIEEYILNNPHCVT 558
Query: 452 IGKPSSKLNEKLENENDSRMKERAKL-FDDAKRKALKESLSQAQHNNNVQIPDDVLGSFE 510
I LE + + E+ K + L + + + P D L
Sbjct: 559 IEMQPDPEKASLEEAEEKSILEKVKASMTEEDLTELARATEELRLKQETPDPPDALKCVP 618
Query: 511 IEN----PQDSVYF-TETKSISCIPVPSNDSDFPLTDNII 545
N P++ +Y TE I+ + V ND T+NI+
Sbjct: 619 SLNLSDIPKEPIYVPTEVGDINGVKVLRNDL---FTNNIL 655
>At3g19170 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase superfamily)
Length = 1052
Score = 121 bits (303), Expect = 6e-27
Identities = 100/352 (28%), Positives = 172/352 (48%), Gaps = 23/352 (6%)
Query: 26 RTKLQLVHLNNKSSPLVQGYFAVGTECPTDS-GVPHTLEHLIFMGSEKYPYKG-LLDTAG 83
+T +++ ++N+ V G V P DS G+PH LEH + GS KYP K ++
Sbjct: 101 KTGCEVMSVSNEDENKVFG--VVFRTPPKDSTGIPHILEHSVLCGSRKYPVKEPFVELLK 158
Query: 84 NLCMSNTNAWTATDQTVYTLSTAGWKGFKKLLPVYLDHLFFPTLTEDACT--TEVYHI-- 139
+ NA+T D+T Y +++ K F L+ VYLD +FFP +DA T E +H
Sbjct: 159 GSLHTFLNAFTYPDRTCYPVASTNTKDFYNLVDVYLDAVFFPKCVDDAHTFQQEGWHYEL 218
Query: 140 -DP-DDLSDKGVVFSEMAGIESQSWFITTLEKQRLLFPEGSGYRSETGGLTPNLRVLTND 197
DP +D+S KGVVF+EM G+ SQ I Q+ L PE + Y ++GG ++ LT +
Sbjct: 219 NDPSEDISYKGVVFNEMKGVYSQPDNILGRIAQQALSPENT-YGVDSGGDPKDIPNLTFE 277
Query: 198 EIREFHKQMYTPDNCCVIITGNIPSEELIELMEIFDKQLPEFTANERKRPFIDTPASQIP 257
E +EFH+Q Y P N + G+ ++ + + + + L F A+ P ++ +
Sbjct: 278 EFKEFHRQYYHPSNARIWFYGD---DDPVHRLRVLSEYLDMFEAS----PSPNSSKIKFQ 330
Query: 258 QSLTEMKEKTIEFPEADE----SQGEVSFSWITQPYLKHIEDQ-AVNILLEYLTESPLAP 312
+ +E ++P + + + +W+ ++ Q A+ L + +P +P
Sbjct: 331 KLFSEPVRLVEKYPAGRDGDLKKKHMLCVNWLLSEKPLDLQTQLALGFLDHLMLGTPASP 390
Query: 313 FNMEMIEIENPYATDAEYWSDDFIRTISNISLKGVPTDRLQQAKEKTLDLLK 364
++E A + SD+ ++ I LKGV + +Q+ +E +D LK
Sbjct: 391 LRKILLESGLGEALVSSGLSDELLQPQFGIGLKGVSEENVQKVEELIMDTLK 442
>Hs7657343 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase superfamily)
Length = 1038
Score = 120 bits (302), Expect = 8e-27
Identities = 121/495 (24%), Positives = 218/495 (43%), Gaps = 42/495 (8%)
Query: 53 PTDS-GVPHTLEHLIFMGSEKYPYKGLLDTAGNLCMSN-TNAWTATDQTVYTLSTAGWKG 110
P DS GVPH LEH + GS+KYP + N +S NA+TA+D T+Y ST K
Sbjct: 96 PMDSTGVPHILEHTVLCGSQKYPCRNPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKD 155
Query: 111 FKKLLPVYLDHLFFPTLTEDACTTEVYHIDPDDLSD-------KGVVFSEMAGIESQSWF 163
F+ LL VYLD F P L E E + ++ ++ SD KGVVF+EM G + +
Sbjct: 156 FQNLLSVYLDATFSPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNER 215
Query: 164 ITTLEKQRLLFPEGSGYRSETGGLTPNLRVLTNDEIREFHKQMYTPDNCCVIITGNIPSE 223
I + Q L P+ + Y +GG + LT +++++FH Y P N GN P E
Sbjct: 216 IFSQHLQNRLLPDHT-YSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLE 274
Query: 224 ELIELMEIFDKQLPEFTANERKRPFIDTPASQIPQSLTEMKEKTIE-------FPEADES 276
+ L +I ++ L +F E P++ +P K + + F
Sbjct: 275 Q--HLKQIHEEALSKFQKIE--------PSTVVPAQTPWDKPREFQITCGPDSFATDPSK 324
Query: 277 QGEVSFSWITQPYLKHIEDQAVNILLEYLTESPLAPFNMEMIE--IENPYATDAEYWSDD 334
Q VS S++ E +++L LT P +PF +IE + ++ D Y +
Sbjct: 325 QTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTEFSPDVGY--NG 382
Query: 335 FIR-TISNISLKGVPTDRLQQAK---EKTLDLLKTHHVSLDRIRLVTENMKWDYIFKFEK 390
+ R ++ L+G+ ++ + ++T+D + + DRI + ++ +
Sbjct: 383 YTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVETRIEDDRIEALLHKIEIQMKHQSTS 442
Query: 391 IGDTMVAHMAITDFLYGATDGGVLE--ESLKTLEDFNILLSWSQEKWQALLEESFVTNQP 448
G + +++A DG +E + L F L + + Q +++ F NQ
Sbjct: 443 FGLMLTSYIASC----WNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQH 498
Query: 449 VVVIG-KPSSKLNEKLENENDSRMKERAKLFDDAKRKALKESLSQAQHNNNVQIPDDVLG 507
+ + +P K +EK +++K++ + R+ + E + + + L
Sbjct: 499 KLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLP 558
Query: 508 SFEIENPQDSVYFTE 522
+ ++ + + ++ TE
Sbjct: 559 ALKVSDIEPTIPVTE 573
>SPBC119.17 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase superfamily)
Length = 882
Score = 112 bits (281), Expect = 2e-24
Identities = 169/765 (22%), Positives = 317/765 (41%), Gaps = 97/765 (12%)
Query: 16 QYHFTKYISTRTKLQLVHLNNKSSPLVQGYFAVGTECPT--DSGVPHTLEHLIFMGSEKY 73
Q ++T+ T ++HL+ + V F++G + P D G+PH LEH GS KY
Sbjct: 48 QLNYTRLKHEPTNADMIHLDREDPNSV---FSIGFQTPAENDEGIPHILEHTTLCGSNKY 104
Query: 74 PYKGLLDTAGNLCMSN-TNAWTATDQTVYTLSTAGWKGFKKLLPVYLDHLFFPTLTEDAC 132
P + N ++ NA+TA+D T Y +T +K L VYLD FP L +
Sbjct: 105 PVRDPFFKMLNRSLATFMNAFTASDFTFYPFATVNTTDYKNLRDVYLDATLFPKLRKLDF 164
Query: 133 TTEVYHIDPDDLSDK-------GVVFSEMAGIESQSWFITTLEKQRLLFPEGSGYRSETG 185
E + + D++DK GVV++EM G S S +I + Q+ LF +G+ Y +G
Sbjct: 165 LQEGWRFEHADVNDKKSPIIFNGVVYNEMKGQVSDSSYIFYMLFQQHLF-QGTAYGFNSG 223
Query: 186 GLTPNLRVLTNDEIREFHKQMYTPDNCCVIITGNIPSEE-LIELMEIFDKQLPEFTANER 244
G + L +E+ +FH+ Y P N ++ G+ P E+ L L E F F+ E
Sbjct: 224 GDPLAIPDLKYEELVKFHRSHYHPSNAKILSYGSFPLEDNLSALSETF----RPFSKREL 279
Query: 245 KRPFIDTPASQIPQSLTEMKEKTIEFPEADESQGEVSFSWITQPYLKHIEDQAVNILLEY 304
P +T + Q ++ ++ A Q + S S++ E A+ +L +
Sbjct: 280 NLP--NTFLKEFDQEKRVVEYGPLDPVMAPGRQVKTSISFLANDTSNVYETFALKVLSKL 337
Query: 305 LTESPLAPFNMEMIE--IENPYATDAEYWSDDFIRTISNISLKGVPTDRLQQAKEKTLDL 362
+ +PF +IE + +A ++ Y S R I ++ L+G + L + + +
Sbjct: 338 CFDGFSSPFYKALIESGLGTDFAPNSGYDSTT-KRGIFSVGLEGASEESLAKIENLVYSI 396
Query: 363 ---LKTHHVSLDRIRLVTENMKWDYIFKFEKIGDTMVAHMAITDFLYGATDGGVLEESLK 419
L +++ + M+ K G + + ++ GA L
Sbjct: 397 FNDLALKGFENEKLEAILHQMEISLKHKSAHFGIGLAQSLPF-NWFNGADPADWL----- 450
Query: 420 TLEDFNILLSWSQEK------WQALLEESFVTNQPVVVIGK-PSSKLNEKLENENDSRMK 472
FN + W ++K +Q L+++ + N+ V PSS ++L+ +++
Sbjct: 451 ---SFNKQIEWLKQKNSDGKLFQKLIKKYILENKSRFVFTMLPSSTFPQRLQEAEAKKLQ 507
Query: 473 ER-AKLFDDAKRKALKESLSQAQHNNNVQIPDDVLGSFEIENPQDSVYFTETKSISCIPV 531
ER +KL D+ + K S+ + + P D+ SC+P
Sbjct: 508 ERTSKLTDEDIAEIEKTSVKLLEAQS---------------TPADT---------SCLPT 543
Query: 532 PSNDSDFPLTDNIINLKPKAFPFFIHFEHFPSQFVEIHVALNV--------DFVKDCELL 583
S SD P T + LK F+ +Q+ ++ L +F + L+
Sbjct: 544 LS-VSDIPETIDETKLK------FLDIAGMKAQWYDLAAGLTYIRLLLPLKNFPE--SLI 594
Query: 584 PYYHVVTELFSMPMIGENGETISFEDVVAQLKTETVETDISMGIGGNFSNLIDFKIQCKA 643
PY V + + +G + E+I D+ Q++ T IS N S++ +++
Sbjct: 595 PYLPVYCD--ACLNLGTHSESIG--DLEHQIRRYTGGISISPSAVTNNSDVSKYELGIAI 650
Query: 644 TNYS------KAVNWLKRVLFD-SVFDESRVSILLEKFYNSIVE-TKREGDQMMFSSMNR 695
+ Y+ K V + + ++ ++ + +++I+L+ + I + +G S
Sbjct: 651 SGYALDKNVGKLVELINKAFWNTNLSNTDKLAIMLKTSVSGITDGIAEKGHSFAKVSSAS 710
Query: 696 HLYNEGSLKKSADELYVEPIIESVLTDIEDGHYIQKILPKLESLR 740
L + S+ + L ++ + + G ++K+ E LR
Sbjct: 711 GLTEKTSITEQLGGLTQVKLLSQLSREESFGPLVEKLTAIREILR 755
>7302255 [RO] KOG2019 Metalloendoprotease HMP1 (insulinase superfamily)
Length = 1112
Score = 103 bits (257), Expect = 1e-21
Identities = 119/533 (22%), Positives = 216/533 (40%), Gaps = 73/533 (13%)
Query: 11 VEYAPQYHFTKYIST--RTKLQLVHLNNKSSPLVQGYFAVGTEC-PTDS-GVPHTLEHLI 66
VE+ ++ T Y RT +L H++ S V F++ P DS G+PH LEHL
Sbjct: 78 VEHISEFELTSYTFRYERTGTELWHIDRNDSNNV---FSINFRTTPFDSTGLPHILEHLS 134
Query: 67 FMGSEKYPYKGLLDTAGNLCMSN-TNAWTATDQTVYTLSTAGWKGFKKLLPVYLDHLFFP 125
GS+KYP + N ++ NA T D T+Y ST F+ L +YLD +F P
Sbjct: 135 LCGSQKYPVRDPFFKMLNRSVATFMNAMTGPDYTIYPFSTMNEIDFRNLQHIYLDAVFRP 194
Query: 126 TLTEDACTTEVYHIDPDDLSD-------KGVVFSEMAGIESQSWFITTLEKQRLLFPEGS 178
L E + ++ D+ D KGVV++EM G S++ + + +FP+ +
Sbjct: 195 NLAYFDFLQEGWRLENKDIFDKQSKLVIKGVVYNEMKGAFSENAQVFSQNLLNNIFPDHT 254
Query: 179 GYRSETGGLTPNLRVLTNDEIREFHKQMYTPDNCCVIITGNIPSEELIELMEIFDKQLPE 238
YR +GG + L +++ EFHK+ Y P N + G + + + L++ ++ L +
Sbjct: 255 -YRHVSGGNPLEIPKLAYNDLVEFHKKYYHPSNARIYSYGLFDASKTLALLD--EEYLSD 311
Query: 239 FTANERKRPFIDTPASQIPQSLTEMKEKTIEFPEADESQGEVSFSWITQPYLKHIEDQAV 298
+ + I L + + + Q +++ + + E +
Sbjct: 312 QSWVDNSYSLIRQQERWTQPRLVHISSRLDNMGTTIDRQNQIAIALLMCDATNIQESFEL 371
Query: 299 NILLEYLTESPLAPFNMEMIE--IENPYATDAEYWSDD---------------------- 334
++L E L P +PF +IE Y Y SD
Sbjct: 372 HVLSEVLIRGPNSPFYKNLIEPNFSGGYNQTTGYSSDTKDTTFVVGLQDLRVEDFKKCIE 431
Query: 335 -FIRTISNISLKGVPTDRLQQAKEKTLDLLKTHHVSLDRIRLVTENMKWDYIFKFEKIGD 393
F +TI N G + ++ LK + + L W++ GD
Sbjct: 432 IFDKTIINSMNDGFDSQHVESVLHNLELSLKHQNPNFGNTLLFNSTALWNH------DGD 485
Query: 394 TMVAHMAITDFLYGATDGGVLEESLKTLEDFNILLSWSQEKWQALLEESFV-TNQPVVVI 452
+V+++ ++D + G L ES +S +++ +Q +E+ F N + +
Sbjct: 486 -VVSNLRVSDMISG------LRES----------ISQNKKYFQEKIEKYFANNNHRLTLT 528
Query: 453 GKPSSKLNEKLENENDSRMKERAKLFDDAK------RKALKESLSQAQHNNNV 499
P +K + ++++ KL D+ K R + +S +A+ N ++
Sbjct: 529 MSPDEAYEDKFKQAELELVEQKVKLLDEVKIEKIYERGLILDSYQKAESNTDL 581
>YDR430c [RO] KOG2019 Metalloendoprotease HMP1 (insulinase superfamily)
Length = 989
Score = 82.8 bits (203), Expect = 3e-15
Identities = 59/207 (28%), Positives = 96/207 (45%), Gaps = 15/207 (7%)
Query: 47 AVGTECPTDSGVPHTLEHLIFMGSEKYPYKGLLDTAGNLCMSN-TNAWTATDQTVYTLST 105
A T P +GVPH LEH GS KYP + N ++N NA T D T + ST
Sbjct: 71 AFKTNPPDSTGVPHILEHTTLCGSVKYPVRDPFFKMLNKSLANFMNAMTGPDYTFFPFST 130
Query: 106 AGWKGFKKLLPVYLDHLFFPTLTEDACTTEVYHIDPDDLSD-------KGVVFSEMAGIE 158
+ F L VYLD P L ++ E + ++ +++D KGVV++EM G
Sbjct: 131 TNPQDFANLRGVYLDSTLNPLLKQEDFDQEGWRLEHKNITDPESNIVFKGVVYNEMKGQI 190
Query: 159 SQSWFITTLEKQRLLFPEGSGYRSETGGLTPNLRVLTNDEIREFHKQMYTPDNCCVIITG 218
S + + + Q+ ++P + +GG + L ++ +FH + Y P N G
Sbjct: 191 SNANYYFWSKFQQSIYPS----LNNSGGDPMKITDLRYGDLLDFHHKNYHPSNAKTFTYG 246
Query: 219 NIPSEELIELMEIFDKQLPEFTANERK 245
N+P L++ ++ ++Q + RK
Sbjct: 247 NLP---LVDTLKQLNEQFSGYGKRARK 270
>ECU06g0750 [O] KOG0959 N-arginine dibasic convertase NRD1 and related
Zn2+-dependent endopeptidases insulinase superfamily
Length = 882
Score = 62.0 bits (149), Expect = 5e-09
Identities = 50/182 (27%), Positives = 83/182 (45%), Gaps = 13/182 (7%)
Query: 53 PTDS-GVPHTLEHLIFMGSEKYPYKGLLDTAGNLCMSNTNAWTATDQTVYTLSTAGWKGF 111
P D+ G+ H LEH++FMG+EKYP + L + NA T + TVY + F
Sbjct: 63 PADAQGLAHFLEHMLFMGTEKYPVEDGLSYFLSKNNGGYNATTYGEATVYYFDVRP-EAF 121
Query: 112 KKLLPVYLDHLFFPTLTEDACTTEVYHIDPDDLSDKGVVFSEMAGIESQSWFITTLEKQR 171
++ + ++ D P L D+ EV ++ + + G+ + W + K +
Sbjct: 122 EEAVDMFADFFKSPLLKRDSVEREVSAVNSEFCN----------GLNNDGWRTWRMMK-K 170
Query: 172 LLFPEGSGYRSETGGLTPNLRVLTNDEIREFHKQMYTPDNCCVIITGNIPSEELIELMEI 231
E + + TG R +E++EF + Y+ D CV+I GN EL EL+
Sbjct: 171 CCKKEQALSKFSTGNYDTLRRDGIWEEMKEFWSRKYSSDKMCVVIYGNKSPGELKELLGK 230
Query: 232 FD 233
F+
Sbjct: 231 FE 232
>7292708 [O] KOG0959 N-arginine dibasic convertase NRD1 and related
Zn2+-dependent endopeptidases insulinase superfamily
Length = 1077
Score = 52.8 bits (125), Expect = 3e-06
Identities = 58/254 (22%), Positives = 104/254 (40%), Gaps = 22/254 (8%)
Query: 57 GVPHTLEHLIFMGSEKYPYKGLLDTAGNLCMSNTNAWTATDQTVYTLSTAGWKGFKKLLP 116
G+ H LEH+IFMGSEKYP + + D C NA T + T++ A K L
Sbjct: 113 GLAHFLEHMIFMGSEKYPKENIFDAHIKKCGGFANANTDCEDTLFYFEVAE-KHLDSSLD 171
Query: 117 VYLDHLFFPTLTEDACTTEVYHIDPDDLSDKGVVFSEMAGIES--QSWFITTLEKQRLLF 174
+ + P + ++A E +D + F ++ + + + +L + F
Sbjct: 172 YFTALMKAPLMKQEAMQRERSAVDSE--------FQQILQDDETRRDQLLASLATKG--F 221
Query: 175 PEGSGYRSETGGLTPNLRVLTNDEI-REFHKQMYTPDNCCVIITGNIPSEELIELMEIFD 233
P G+ L N+ +I E K+ Y + V + +P +EL L+
Sbjct: 222 PHGTFAWGNMKSLKENVDDAELHKILHEIRKEHYGANRMYVCLQARLPIDELESLVVRHF 281
Query: 234 KQLPEFTANERKRPFIDTPASQIPQSLTEMKEKTIEFPEADESQGEVSFSWI---TQPYL 290
+P NE K P D + + + + F + E++ ++ +W+ + Y
Sbjct: 282 SGIPH---NEVKAP--DLSSFNYKDAFKAEFHEQVFFVKPVENETKLELTWVLPNVRQYY 336
Query: 291 KHIEDQAVNILLEY 304
+ DQ ++ LL Y
Sbjct: 337 RSKPDQFLSYLLGY 350
>At2g41790 [O] KOG0959 N-arginine dibasic convertase NRD1 and related
Zn2+-dependent endopeptidases insulinase superfamily
Length = 970
Score = 52.4 bits (124), Expect = 4e-06
Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 29/246 (11%)
Query: 57 GVPHTLEHLIFMGSEKYPYKGLLDTAGNLCMSNTNAWTATDQTVYTLSTAGWKGFKKLLP 116
G+ H LEH++F SEKYP + +TNA+TA+++T Y F + L
Sbjct: 66 GLAHFLEHMLFYASEKYPEEDSYSKYITEHGGSTNAYTASEETNYHFDVNA-DCFDEALD 124
Query: 117 VYLDHLFFPTLTEDACTTEVYHIDPDDLSDKGVVFSEMAGIESQSWFITTLEKQRLLFPE 176
+ P ++ DA E+ +D ++ + S W I L+K L E
Sbjct: 125 RFAQFFIKPLMSADATMREIKAVDSEN----------QKNLLSDGWRIRQLQKH--LSKE 172
Query: 177 GSGYRSETGGLTPNLRVL-------TNDEIREFHKQMYTPDNCCVIITGNIPSEELIELM 229
Y + G L V T E+ +F+++ Y+ + +++ G E L ++
Sbjct: 173 DHPYHKFSTGNMDTLHVRPQAKGVDTRSELIKFYEEHYSANIMHLVVYG---KESLDKIQ 229
Query: 230 EIFDKQLPEFTANERKRPFIDTPASQIPQSLTEMKEKTIEFPEADESQGEVSFSWITQPY 289
++ ++ E + P P ++ K I + ++ SW P
Sbjct: 230 DLVERMFQEIQNTNKVVPRF--PGQPCTADHLQILVKAIPIKQGH----KLGVSWPVTPS 283
Query: 290 LKHIED 295
+ H ++
Sbjct: 284 IHHYDE 289
>7296294 [O] KOG0959 N-arginine dibasic convertase NRD1 and related
Zn2+-dependent endopeptidases insulinase superfamily
Length = 990
Score = 52.0 bits (123), Expect = 5e-06
Identities = 45/188 (23%), Positives = 78/188 (40%), Gaps = 21/188 (11%)
Query: 44 GYFAVGTECPTDSGVPHTLEHLIFMGSEKYPYKGLLDTAGNLCMSNTNAWTATDQTVYTL 103
G+ + T P G+ H EH++F+G+EKYP++ T + ++NA T T Y
Sbjct: 68 GHMSDPTNLP---GLAHFCEHMLFLGTEKYPHENGYTTYLSQSGGSSNAATYPLMTKYHF 124
Query: 104 STAGWKGFKKLLPVYLDHLFFPTLTEDACTTEVYHIDPDDLSDKGVVFSEMAGIESQSWF 163
A K L + P T A E+ ++ + + S W
Sbjct: 125 HVAPDK-LDGALDRFAQFFIAPLFTPSATEREINAVNSE----------HEKNLPSDLWR 173
Query: 164 ITTLEKQRLLFPE------GSGYRSETGGLTPNLRVLTNDEIREFHKQMYTPDNCCVIIT 217
I + + L P+ GSG ++ + + + DE+ +FHKQ Y+ + C+ +
Sbjct: 174 IKQVNR-HLAKPDHAYSKFGSGNKTTLSEIPKSKNIDVRDELLKFHKQWYSANIMCLAVI 232
Query: 218 GNIPSEEL 225
G +EL
Sbjct: 233 GKESLDEL 240
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,940,471
Number of Sequences: 60738
Number of extensions: 2715844
Number of successful extensions: 7291
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 7239
Number of HSP's gapped (non-prelim): 17
length of query: 1037
length of database: 30,389,216
effective HSP length: 117
effective length of query: 920
effective length of database: 23,282,870
effective search space: 21420240400
effective search space used: 21420240400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)