ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7201 good L KOG1133 Replication, recombination and repair Helicase of the DEAD superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7201 2513059 2510639 -807
(807 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL008w [L] KOG1133 Helicase of the DEAD superfamily 720 0.0
SPAC3G6.11 [L] KOG1133 Helicase of the DEAD superfamily 481 e-135
Hs13787197 [L] KOG1133 Helicase of the DEAD superfamily 393 e-109
At1g79890 [L] KOG1133 Helicase of the DEAD superfamily 390 e-108
Hs22057889 [L] KOG1133 Helicase of the DEAD superfamily 369 e-102
CE03493 [L] KOG1133 Helicase of the DEAD superfamily 342 1e-93
7290134 [L] KOG1133 Helicase of the DEAD superfamily 342 1e-93
Hs13787200 [L] KOG1133 Helicase of the DEAD superfamily 335 2e-91
Hs14765656 [L] KOG1133 Helicase of the DEAD superfamily 242 1e-63
ECU02g1090 [L] KOG1132 Helicase of the DEAD superfamily 202 1e-51
ECU08g1120 [L] KOG1133 Helicase of the DEAD superfamily 195 2e-49
7290625 [L] KOG1132 Helicase of the DEAD superfamily 181 4e-45
CE28992 [KL] KOG1131 RNA polymerase II transcription initiation/... 152 2e-36
SPAC1D4.12 [KL] KOG1131 RNA polymerase II transcription initiati... 151 3e-36
YER171w [KL] KOG1131 RNA polymerase II transcription initiation/... 142 2e-33
Hs15834617 [KL] KOG1131 RNA polymerase II transcription initiati... 132 2e-30
7291258 [KL] KOG1131 RNA polymerase II transcription initiation/... 129 1e-29
Hs14042978 [L] KOG1132 Helicase of the DEAD superfamily 129 2e-29
Hs7706541_1 [L] KOG1132 Helicase of the DEAD superfamily 127 9e-29
Hs14790174_1 [L] KOG1132 Helicase of the DEAD superfamily 127 9e-29
At1g79950 [L] KOG1132 Helicase of the DEAD superfamily 126 2e-28
ECU06g0200 [KL] KOG1131 RNA polymerase II transcription initiati... 124 4e-28
CE15894 [L] KOG1132 Helicase of the DEAD superfamily 119 1e-26
CE17764 [L] KOG1132 Helicase of the DEAD superfamily 113 1e-24
At1g03190 [KL] KOG1131 RNA polymerase II transcription initiatio... 94 1e-18
At1g20750 [L] KOG1132 Helicase of the DEAD superfamily 92 3e-18
At1g20720 [L] KOG1132 Helicase of the DEAD superfamily 79 2e-14
Hs13787199 [L] KOG1133 Helicase of the DEAD superfamily 74 9e-13
>YPL008w [L] KOG1133 Helicase of the DEAD superfamily
Length = 861
Score = 720 bits (1859), Expect = 0.0
Identities = 403/852 (47%), Positives = 551/852 (64%), Gaps = 55/852 (6%)
Query: 3 KNFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEK 62
+ F+HPY+PYDIQ QLME +Y +L+ GKK+ I ESPTGTGKTLSLIC+T+TWLR +K +
Sbjct: 8 ETFYHPYKPYDIQVQLMETVYRVLSEGKKIAILESPTGTGKTLSLICATMTWLRMNKADI 67
Query: 63 LNSKVDNDNLS-DSTFSSSDDEPEWVNQFYNDKIMKEKSKSLQEYENYLEGLSMSNIKPV 121
N + D + + SDDEP+WV Y +++EK L +YE +L ++ ++ K +
Sbjct: 68 FTRMETNIKTNEDDSENLSDDEPDWVIDTYRKSVLQEKVDLLNDYEKHLNEINTTSCKQL 127
Query: 122 LRQLDIGDR----------KRKKTVPRHIEIEIEDDETNFLPEPYEQDSVSNQN------ 165
D+ ++K+ RH+++ +E E +F+P PYE DS +N
Sbjct: 128 KTMCDLDKEHGRYKSVDPLRKKRKGARHLDVSLE--EQDFIPRPYESDSENNDTSKSTRG 185
Query: 166 ------DYEKGQINDEIQKLLAKIDKGYDVKTENNMEL-----KSPLKIYFSSRTHSQLT 214
DY+ ++N +I LL KID G + NN + ++P+KIY++SRT+SQL
Sbjct: 186 GRISDKDYKLSELNSQIITLLDKID-GKVSRDPNNGDRFDVTNQNPVKIYYASRTYSQLG 244
Query: 215 QFAXXXXXXXX-XXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKS-DLINDACVETVKR 272
QF E++K+LPLAS+KQLCI+ KV K K+ + INDAC +
Sbjct: 245 QFTSQLRLPSFPSSFRDKVPDEKVKYLPLASKKQLCINPKVMKWKTLEAINDACADLRHS 304
Query: 273 QE-CQFYTNS---RDLISSKQFRDYTFSEISDIEDLVQLGHSLHVCPYYSSRTALEGAEI 328
+E C FY N+ R + RD FSEI DIEDLV LG SL +CPYY+SR AL AE+
Sbjct: 305 KEGCIFYQNTNEWRHCPDTLALRDMIFSEIQDIEDLVPLGKSLGICPYYASREALPIAEV 364
Query: 329 VTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCEISLSDIKICKKLMKI 388
VTLPYQ++LS R SL INL++SIVIIDEAHNL++TI SIYS +ISL D+K C K +
Sbjct: 365 VTLPYQYLLSESTRSSLQINLENSIVIIDEAHNLIETINSIYSSQISLEDLKNCHKGIVT 424
Query: 389 YLNKFKRKLNGKNRVNIMKLMKLLDILQAFIESHFEK-GKEISPQSMFRDSNADLLNIHE 447
Y NKFK +LN NRVN++KL LL L FI +F+K G+EI P MF SN D LNIH+
Sbjct: 425 YFNKFKSRLNPGNRVNLLKLNSLLMTLIQFIVKNFKKIGQEIDPNDMFTGSNIDTLNIHK 484
Query: 448 LVTYMRGSKIAYKIDSYADSKLKSDES--NTNSVK---------QPILFKISKFVLSLSN 496
L+ Y++ SKIAYKID+Y + LK +ES N N +K QP+LFK+S+F+ L+N
Sbjct: 485 LLRYIKVSKIAYKIDTY-NQALKEEESSKNENPIKETHKKSVSSQPLLFKVSQFLYCLTN 543
Query: 497 PXXXXXXXXXXXMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPFVPSK 556
IKYMLLEP++ F++I+N +KCV+LAGGTM+P SEF+ NLLP VPS+
Sbjct: 544 LTSEGQFFFEKNYSIKYMLLEPSKPFESILNQAKCVVLAGGTMEPMSEFLSNLLPEVPSE 603
Query: 557 DIVQFSCNHIIPESNLDTFIVSEG-FNFNYESRNNESVMCK-LYDFLLELGCRVPH--GI 612
DI SCNH+IP+ NL T+I ++ F +E R + S++ L+ F ++L VP GI
Sbjct: 604 DITTLSCNHVIPKENLQTYITNQPELEFTFEKRMSPSLVNNHLFQFFVDLSKAVPKKGGI 663
Query: 613 VVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSDILPQYSSTILDKKKGAFLF 672
V FFPSY YL HVI+ W+ + F L+ ++IFYE G DIL YS ++ + + G+ L
Sbjct: 664 VAFFPSYQYLAHVIQCWKQNDRFATLNNVRKIFYEAKDGDDILSGYSDSVAEGR-GSLLL 722
Query: 673 SVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSA 732
++VGGKLSEGINFQD+L RAVVMVGLP+PN++S EL+VK++H+ K++ +GG+ ++A A
Sbjct: 723 AIVGGKLSEGINFQDDLCRAVVMVGLPFPNIFSGELIVKRKHLAAKIMKSGGTEEEASRA 782
Query: 733 TIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKSELKT 792
T EF ENICMKAVNQS+GRAIRHANDYA IYL+D RY + KLS WV+ + SE T
Sbjct: 783 TKEFMENICMKAVNQSVGRAIRHANDYANIYLLDVRYNRPNFRKKLSRWVQDSINSEHTT 842
Query: 793 SEIFAQTSVFFA 804
++ + T FF+
Sbjct: 843 HQVISSTRKFFS 854
>SPAC3G6.11 [L] KOG1133 Helicase of the DEAD superfamily
Length = 844
Score = 481 bits (1237), Expect = e-135
Identities = 303/853 (35%), Positives = 464/853 (53%), Gaps = 72/853 (8%)
Query: 4 NFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKL 63
NFHHPY PYDIQ + M +Y ++ GK +GIFESPTGTGK+LSLIC+++TWL EH L
Sbjct: 12 NFHHPYTPYDIQLEFMRSLYSSISDGK-IGIFESPTGTGKSLSLICASLTWLDEHGGVLL 70
Query: 64 NSKVDNDNLSDSTFSSSDDEPEWVNQFYNDKIMKEKSKSLQ-EYENYLEGLSMSNIKPVL 122
DN+ +D+ ++S P+WV + + KI K+ K E LE + N
Sbjct: 71 E---DNEKSNDNKSNTSSKIPDWVLE-QDLKIQKDLVKETHARLEQRLEEIRKRNQSRKN 126
Query: 123 RQLDIGDRKRKKTVPRHIEIEIEDDE----TNFLPEPYEQDSVSNQNDYEKGQINDEIQK 178
+ + ++T R+I E + +N +P ++ V+ + Y +++ +
Sbjct: 127 QMSNNSTTYHRETKRRNINAEASTSDNCNNSNTSVDPMDEYLVTAE--YTMPSTSEQSED 184
Query: 179 LLAKIDKGYDVKTENNMELKSP--------LKIYFSSRTHSQLTQFAXXXXXXXXXXXXX 230
L + GY K + SP KIYF+SRTHSQL Q
Sbjct: 185 LF---NNGYSSKVSELLRKLSPDNEKPPIVQKIYFTSRTHSQLQQLVQEIKKLNNQTFST 241
Query: 231 XXEKERIKFLPLASRKQLCIHAKVSKLK-SDLINDACVETV-KRQECQFYTNSRDLISSK 288
I+ + LASRK LCI+ +V KL+ + +N+ C+E +C F ++ L
Sbjct: 242 P-----IRVVSLASRKNLCINNEVRKLRPTSALNEKCIELQGSAHKCPFLQDNTQLWD-- 294
Query: 289 QFRDYTFSEISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGIN 348
FRD +EI DIE+LV+LG L VCPYY +R A++ A+IVTLPY +L R +L +
Sbjct: 295 -FRDEALAEIMDIEELVELGQRLKVCPYYGTREAVDSAQIVTLPYPLLLQESARNALNLT 353
Query: 349 LKDSIVIIDEAHNLMDTITSIYSCEISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKL 408
LKD+I IIDEAHNL+D I S++S IS + I + ++ Y +F+++LNG NR++I +L
Sbjct: 354 LKDNICIIDEAHNLIDAICSMHSSSISFRQVCIAETQLQQYFLRFEKRLNGNNRMHIKQL 413
Query: 409 MKLLDILQAFIESHFE---KGKEISPQSMFRDSNADLLNIHELVTYMRGSKIAYKIDSYA 465
+K++ L++F + E K I+ S+ + AD +N+H L Y+ SK+A K+D Y
Sbjct: 414 IKVVYNLKSFFLNCLETNTNSKVINVDSLLVSNGADQINLHHLSEYLNVSKLARKVDGYT 473
Query: 466 D-------------SKLKSDE-SNTNSVKQ----PILFKISKFVLSLSNPX----XXXXX 503
+ L+S+ SN N ++ P+L ++ F+L+++NP
Sbjct: 474 KYMHSLGTQELESLNDLRSERFSNGNGYEEDPYTPVLMQLESFLLNIANPAPEGKLFYEK 533
Query: 504 XXXXXMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPFVPSKDIVQFSC 563
+KY+LL+P++ + + + V LAGGTM P +FI L S+ I+ FSC
Sbjct: 534 QTGDNPYLKYLLLDPSKHVEILTEQCRSVNLAGGTMSPIDDFITLLFSDEQSR-ILPFSC 592
Query: 564 NHIIPESNLDTFIVSEG-----FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPS 618
+HI+P N+ T +VS+G F F ++ +++E+++ L +P G+VVFFPS
Sbjct: 593 DHIVPPENITTILVSQGPAGVPFEFTHKRKDDENLLKDLGRTFQNFISIIPDGVVVFFPS 652
Query: 619 YGYLEHVIKFWQLEEIFEKLSMNKRIFYET----PGGSDILPQYSSTILDKKKGAFLFSV 674
+ +L+ +K W++ I +L+ K +F E+ D Y ++ D LFSV
Sbjct: 653 FAFLQQAVKVWEMNGITNRLNAKKPLFIESKDFGDNPLDTFEHYKQSV-DAGLSGMLFSV 711
Query: 675 VGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATI 734
+GG+LSEGINF D L RAV++VG+P+PN E K ++E+K G +AK A+
Sbjct: 712 IGGRLSEGINFSDKLGRAVMVVGMPFPNSQDVEWQAKVSYVEEKAKEKG---INAKQASQ 768
Query: 735 EFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKSELKTSE 794
EFYEN CM+AVNQSIGRAIRH +DYA I L+D+RY + +Q KL W+ K + S
Sbjct: 769 EFYENTCMRAVNQSIGRAIRHRDDYASIILLDSRYNRSSIQRKLPNWLSKNIHSSPNFGP 828
Query: 795 IFAQTSVFFASNR 807
Q + FF + +
Sbjct: 829 AIRQLATFFRAKK 841
>Hs13787197 [L] KOG1133 Helicase of the DEAD superfamily
Length = 906
Score = 393 bits (1010), Expect = e-109
Identities = 281/898 (31%), Positives = 434/898 (48%), Gaps = 140/898 (15%)
Query: 4 NFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKL 63
+F P+ PY IQ M +Y +L +GK +GIFESPTGTGK+LSLIC ++WLR+ + +K
Sbjct: 12 HFPFPFTPYSIQEDFMAELYRVLEAGK-IGIFESPTGTGKSLSLICGALSWLRDFEQKKR 70
Query: 64 NSKVD---------NDNLSDSTFSSSD-----------DEPEWVNQFYN--------DKI 95
+ +D +S SS EP WV QF D++
Sbjct: 71 EEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRL 130
Query: 96 MKEKSKSLQEYENYLEGLSMSNIKPVLRQLDIGDRKRKKTVPRHIEIEIEDDETNFLPEP 155
E+++ Q E + +K ++L + +R+ + E+ E L +
Sbjct: 131 KAEQARRKQREERLQQLQHRVQLKYAAKRLRQEEEERENLLRLSREMLETGPEAERLEQL 190
Query: 156 YEQDSVSNQNDYEKGQINDEIQKLLAKIDKGYDVKTENNMELKSPLKIYFSSRTHSQLTQ 215
+ +YE +DE +K+ +++D+ E+++E + KIY+ SRTHSQL Q
Sbjct: 191 ESGEEELVLAEYE----SDEEKKVASRVDED-----EDDLEEEHITKIYYCSRTHSQLAQ 241
Query: 216 FAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKS-DLINDACVETVK--- 271
F + ++ + L SR+ LC++ V L S LIND CV+ +
Sbjct: 242 FVHEVKKSPFG--------KDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRH 293
Query: 272 --------------RQE----CQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHV 313
RQE C FY + + + RD +E+ D+E L+ LG
Sbjct: 294 EKKKGAEEEKPKRRRQEKQAACPFYNHEQMGL----LRDEALAEVKDMEQLLALGKEARA 349
Query: 314 CPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCE 373
CPYY SR A+ A++V LPYQ +L R++ GI L+D +VIIDEAHNL+DTIT ++S E
Sbjct: 350 CPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVE 409
Query: 374 ISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKLMKLLDILQAFI----------ESHF 423
+S S + + Y+ ++ ++L KN + + +++ LL+ A + +S
Sbjct: 410 VSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLS 469
Query: 424 EKGKEISPQSMFR-DSNADLLNIHELVTYMRGSKIAYKIDSYADS--------------- 467
+ G E+ + F S D +N+ ++ Y S I+ K+ + +
Sbjct: 470 QTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGAVFSSREQPKLAG 529
Query: 468 ----------------KLKSDESNTNSVKQPI-LFKISKFVLSLSNPXXX-----XXXXX 505
+DES ++++ L I F+ +L+
Sbjct: 530 FQQFLQSLQPRTTEALAAPADESQASTLRPASPLMHIEGFLAALTTANQDGRVILSRQGS 589
Query: 506 XXXMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPF--VPSKDIVQFSC 563
+K++LL P F +V + + V++AGGTMQP S+F + LL V ++ +V+FSC
Sbjct: 590 LSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSDFRQQLLACAGVEAERVVEFSC 649
Query: 564 NHIIPESNLDTFIVSEGFN-----FNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPS 618
H+IP N+ ++ G + F ++ R +M ++ L L VP G+V FFPS
Sbjct: 650 GHVIPPDNILPLVICSGISNQPLEFTFQKRELPQMMDEVGRILCNLCGVVPGGVVCFFPS 709
Query: 619 YGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGG---SDILPQYSSTIL------DKKKGA 669
Y YL V W+ + +L+ K+IF E +L YS I + GA
Sbjct: 710 YEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSRCIQACGQERGQVTGA 769
Query: 670 FLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDA 729
L SVVGGK+SEGINF DNL R VVMVG+P+PN+ S+EL K +++Q + A G
Sbjct: 770 LLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPGQAPPG 829
Query: 730 KSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVK 787
K+ EN+CMKAVNQSIGRAIRH D+A I L+D RY V KL W+R RV+
Sbjct: 830 KA----LVENLCMKAVNQSIGRAIRHQKDFASIVLLDQRYARPPVLAKLPAWIRARVE 883
>At1g79890 [L] KOG1133 Helicase of the DEAD superfamily
Length = 882
Score = 390 bits (1001), Expect = e-108
Identities = 282/878 (32%), Positives = 433/878 (49%), Gaps = 137/878 (15%)
Query: 8 PYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKLNSKV 67
PY+PY IQ M +Y+ L+ G V + ESPTGTGK+LS+ICS + WL + K ++ +
Sbjct: 11 PYKPYSIQIDFMNALYQFLDKGG-VSMLESPTGTGKSLSIICSALQWLTDRKEKRNSGLT 69
Query: 68 DNDNLSDSTFSSSDDEPEWVNQFYNDKIMKEKSKSLQEYENYLEGLSMSNIKPVLRQLDI 127
+ + D + +DEP+W+ F +L E + S+ N K
Sbjct: 70 EESHKVDG--NDDEDEPDWMRNF-----------TLNEADGANGDKSIKNTKSPFSL--- 113
Query: 128 GDRKRKKTVPRHIEIEIEDDETNFLPEPYEQDSVSNQNDYEKGQINDEIQKLLAKIDKGY 187
RK K V E E ++ FL + YE +Q++ G N + K +G+
Sbjct: 114 --RKHAKEVFTEGEKADELNDQEFLLDEYE-----SQDESSPGGGNSK-----RKPARGF 161
Query: 188 DVKTENNMELKSP--------LKIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKF 239
D + + E ++ K++F SRTHSQL+QF +++K
Sbjct: 162 DSSSSEDEEDENDCSDDEQGGFKVFFCSRTHSQLSQFVKELRKTVFA--------KKLKV 213
Query: 240 LPLASRKQLCIHAKVSKLKS-DLINDACVETVKRQECQFYTNS----------------- 281
+ L SRK LCI+ V KL + IN+ C++ K++ Q
Sbjct: 214 VCLGSRKNLCINEDVLKLGNVTRINERCLDLQKKKISQVSKKKNLGANVRIVRTKASCRC 273
Query: 282 ---RDLISSKQFRDYTFS-EISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHIL 337
R ++F+ +F E DIEDLVQLG + CPYY SR A++V LPYQ +L
Sbjct: 274 PMLRKHKLQREFKAESFQQEAMDIEDLVQLGREMRTCPYYGSRRMAPAADLVILPYQSLL 333
Query: 338 SFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCEISLSDIKICKKLMKIYLNKFKRKL 397
S RESLG++LK+S+VIIDEAHNL DT+ S++ ++++S ++ ++ YL +F+ L
Sbjct: 334 SKSSRESLGLSLKNSVVIIDEAHNLADTLLSMHDAKLTVSQLEDIHCSIESYLGRFQNLL 393
Query: 398 NGKNR--VNIMKLM------------KLLDILQAFIESHFEKGKEISPQSM-----FRDS 438
NR + IM ++ L + + K K SM
Sbjct: 394 GAGNRRYIQIMLILTRAFLKPLASDRNLSSVNVGLDTENPSKSKPCGACSMAIYDFLFSL 453
Query: 439 NADLLNIHELVTYMRGSKIAYKIDSYAD---SKLKSDESNTNSVKQPILFK-ISKFVLSL 494
N D +N+ +L+ Y++ S I +K+ Y + + L+ D + + F+ S +++L
Sbjct: 454 NIDNINLVKLLAYIKESNIIHKVSGYGERVAAMLQKDPVAHEEMSKLTSFRAFSDMLVAL 513
Query: 495 SN---------PXXXXXXXXXXXMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEF 545
+N IKY++L ++F +V+++ VILAGGT+QP E
Sbjct: 514 TNNNGDGRIIISRTSSSTSGQHGGYIKYVMLTGAKLFSEVVDEAHAVILAGGTLQPIEET 573
Query: 546 IENLLPFVPSKDIVQFSCNHIIPESNLDTFIVSEG-----FNFNYESRNNESVMCKLYDF 600
E L P++PS + FSC+HI+P ++ VS G F+F++ SR++ ++ +L
Sbjct: 574 RERLFPWLPSNQLQFFSCSHIVPPESIMPIAVSHGPSGQSFDFSHSSRSSIGMIQELGLL 633
Query: 601 LLELGCRVPHGIVVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSD---ILPQ 657
+ L VP GI+VFF S+ Y V W I ++ KR+F E ++ +L
Sbjct: 634 MSNLVAVVPEGIIVFFSSFEYETQVHTAWSNSGILRRIVKKKRVFREPRKNTEVEAVLRD 693
Query: 658 YSSTILDKKKGAFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQ 717
Y I + ++GA + +VVGGK+SEGINF D++ R VVMVGLPYP+ ELL + +HIE
Sbjct: 694 YKEAI-ESERGAIMLAVVGGKVSEGINFSDSMCRCVVMVGLPYPSPSDIELLERIKHIEG 752
Query: 718 KV--------------------ISAG-GSLKDAKSATIEFYENICMKAVNQSIGRAIRHA 756
+ + AG G LK K E+YEN+CMKAVNQSIGRAIRH
Sbjct: 753 RADSDSIKPSVTLVDDSYYSGDVQAGFGVLKSCKRRGKEYYENLCMKAVNQSIGRAIRHE 812
Query: 757 NDYACIYLVDNRYLNNKVQ--------HKLSEWVRKRV 786
DYA I LVD RY N+ + +KL +W++ R+
Sbjct: 813 KDYASILLVDARYSNDPSKRTSHSHPSNKLPKWIKDRL 850
>Hs22057889 [L] KOG1133 Helicase of the DEAD superfamily
Length = 960
Score = 369 bits (948), Expect = e-102
Identities = 278/884 (31%), Positives = 419/884 (46%), Gaps = 148/884 (16%)
Query: 4 NFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKL 63
+F P+ PY IQ M +Y +L +GK +GIFESPTGTGK+LSLIC ++WLR+ + +K
Sbjct: 12 HFPFPFTPYSIQEDFMAELYRVLEAGK-IGIFESPTGTGKSLSLICGALSWLRDFEQKKR 70
Query: 64 NSKVD---------NDNLSDSTFSSSD-----------DEPEWVNQFYNDK--------I 95
+ +D +S SS EP WV QF K +
Sbjct: 71 EEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVNRL 130
Query: 96 MKEKSKSLQEYENYLEGLSMSNIKPVLRQLDIGDRKRKKTVPRHIEIEIEDDETNFLPEP 155
E+++ Q E + +K ++L + +R+ + + E ET E
Sbjct: 131 KAEQARRKQREERLQQLQHRVQLKYAAKRLRQEEEERENL----LRLSREMLETGPEAER 186
Query: 156 YEQDSVSNQNDYEKGQINDEIQKLLAKIDKGYDVKTENNMELKSPLKIYFSSRTHSQLTQ 215
EQ + +DE +K+ +++D+ E+++E + KIY SRTHSQL Q
Sbjct: 187 PEQLESGEEELVLAEYESDEEKKVASRVDED-----EDDLEEEHITKIYHCSRTHSQLAQ 241
Query: 216 FAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKS-DLINDACVETVK--- 271
F + ++ + L SR+ LC++ V L S LIN+ CV+ +
Sbjct: 242 FVHEVKKSPFG--------KDVRLVSLGSRQNLCVNEDVRSLGSVQLINNRCVDMQRSRH 293
Query: 272 --------------RQE----CQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHV 313
RQE C FY + + + RD +E+ D+E L+ LG
Sbjct: 294 EKKKGAEEEKPKRRRQEKQAACPFYNHEQMGL----LRDEALAEVKDMEQLLALGKEARA 349
Query: 314 CPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCE 373
CPYY SR A+ A++V LPYQ +L R++ GI L+D +VIIDEAHNL+DT TS++S E
Sbjct: 350 CPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTTTSMHSVE 409
Query: 374 ISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKLMKLLDILQAFI-------------E 420
+S S + + Y+ ++ ++L K N+M L ++L +L+ F+ +
Sbjct: 410 VSGSQLCQAHSQLLQYMERYGKRLKAK---NLMYLKQILYLLEKFVAVLGGNIKQNPNTQ 466
Query: 421 SHFEKGKEISPQSMFR-DSNADLLNIHELVTYMRGSKIAYKIDSYADS------------ 467
S + G E+ + F S D +N+ ++ Y S I+ K+ + +
Sbjct: 467 SLSQTGMELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGAVFSSREQPK 526
Query: 468 -------------------KLKSDESNTNSVKQPI--LFKISKFVLSLSNP-----XXXX 501
+DES SV QP L I F+ +L+
Sbjct: 527 LAGFQQFLQSLQPRTTEALAAPADESQA-SVPQPASPLMHIEGFLAALTTANQDGRVILS 585
Query: 502 XXXXXXXMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPF--VPSKDIV 559
+K++LL P F +V + + V++AGGTMQP S F + LL V ++ +V
Sbjct: 586 RQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSNFRQQLLACAGVEAERVV 645
Query: 560 QFSCNHIIPESNLDTFIVSEG-----FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVV 614
+FSC H+IP N+ ++ G F ++ R+ +M ++ L L V G+V
Sbjct: 646 EFSCGHVIPPDNILPLVICSGVSNQPLEFTFQKRDLPQMMDEVGRILCNLCGVVSGGVVC 705
Query: 615 FFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGG---SDILPQYS------STILDK 665
FFPSY YL V W+ + +L+ K+IF E +L YS
Sbjct: 706 FFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSRCGQACGQERGP 765
Query: 666 KKGAFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGS 725
GA L SVVGGK+SEGINF DNL R VVMVG+P+PN+ S+EL K +++Q + A G
Sbjct: 766 VTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPGQ 825
Query: 726 LKDAKSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRY 769
K+ EN+CMKAVNQSIGRAIRH D+A I L+D RY
Sbjct: 826 AHPGKA----LVENLCMKAVNQSIGRAIRHQKDFASIVLLDQRY 865
>CE03493 [L] KOG1133 Helicase of the DEAD superfamily
Length = 848
Score = 342 bits (878), Expect = 1e-93
Identities = 266/893 (29%), Positives = 422/893 (46%), Gaps = 142/893 (15%)
Query: 5 FHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLE--- 61
F P+QPYDIQ LM I + + +K+GIFESPTGTGK+LS++CST+TWL +L
Sbjct: 4 FSFPFQPYDIQLNLMREIRQCIEQ-RKIGIFESPTGTGKSLSVLCSTMTWLEAEELRIST 62
Query: 62 KLNSKVDNDNLSDSTFSSSDDEPEWVNQFYNDKIMKEKSKSLQEYENYLEGLS-----MS 116
L++++ + + W + ++EK ++ LE + S
Sbjct: 63 DLSTRLGEVHTKITECDKITTADNW------ETAVREKMRAQDVETEILEQIQSRERLQS 116
Query: 117 NIKPVLRQLDIGDRKRKKTVPRHIEIEIEDDETNFLPEPYEQDSVSNQNDYEKGQINDEI 176
I R + RKRK D FL EP QD + +Y NDE
Sbjct: 117 RIDQARRGMVEVSRKRKAPAR---------DTDQFL-EP--QDEAAPSEEYN----NDEK 160
Query: 177 QKLLAKIDKGYDVKTENNMELKSPLKIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKER 236
+ D DV E LK LKI+++SRTHSQL Q A E +
Sbjct: 161 SEKQRDSDFFDDVDEEEEKPLKC-LKIFYASRTHSQLEQLAE--------------ELAK 205
Query: 237 IKFLP----LASRKQLCIHAKVSKLK-SDLINDACVETVKR--------QECQFYTNSRD 283
+F P ASR LC++ +V KLK + LIN+ C+E K Q+ + T +
Sbjct: 206 TRFQPRIVTCASRGTLCVNEEVKKLKLNHLINEKCMELRKNGMSEKEKVQKLEKGTTKKT 265
Query: 284 LISSKQFRDYTFSEISDIEDLV---QLGHSLHV---------CPYYSSRTALEGAEIVTL 331
+ Y ++I D+ + V +L +L V CPY+++R ++ ++V L
Sbjct: 266 KTCATSCEFYNSTQIEDVVNGVLSNKLKSTLEVSKQGKLSNGCPYFATRKSVPQCQLVLL 325
Query: 332 PYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITS------------------IYSCE 373
PYQ +L R++ GI LKD+++++DEAHN+++TI+S +YS E
Sbjct: 326 PYQVLLHDGTRKAWGIELKDNVIVLDEAHNVLNTISSFFFRKLEKVSKNGFKNCSLYSAE 385
Query: 374 ISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKLMKLLDILQAFIESHFEKGKEISPQS 433
IS + + +L++ Y +K KL N + + +L L + F+ S K ++
Sbjct: 386 ISTKSLTLALRLIREYNAHYKLKLLAHNLLYMKQLESLTSKMLIFLNSQ-SKEDVMTMAQ 444
Query: 434 MFRDSNADLLNIHELVTYMRGSKIAYKIDSYADSKLKSDESNTNSVKQPI---------- 483
+ R+ N +N+ +L YM + + K + +L+ +E + K +
Sbjct: 445 LARNLNILEINLFKLAEYMEKTDLCKKFHGFY-MRLQKEEIKKENEKPKLTGIQKLMAAK 503
Query: 484 --------------------LFKISKFVLSLSNP---XXXXXXXXXXXMIIKYMLLEPNQ 520
LF + F+ +L+N ++MLL P
Sbjct: 504 EAEPEPEAEPLPPPKPVPSPLFSLKSFIDALTNKCEDGRIIVEKSATEAKFRFMLLNPAD 563
Query: 521 IFKTIVNDSKCVILAGGTMQPTSEFIENLLP-FVPSKDIVQFSCNHIIPESNL-----DT 574
+V ++ IL GGTM+P +E L + + I +FSC H+I +S L +
Sbjct: 564 RLSEVVTSARATILVGGTMEPAQLLVETLSRGSIGADSIRRFSCCHVIDDSQLLAVTVER 623
Query: 575 FIVSEGFNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKFWQLEEI 634
+ + F Y++R ++ + L + L +P+G+V+F PSY +L + K + I
Sbjct: 624 TVDGKPFQLTYQTRGADTTLRSLATSIQALIPHIPNGVVIFVPSYDFLFNFQKKMKEFGI 683
Query: 635 FEKLSMNKRIFYET-PGGSDILPQYSSTILDKKKGAFLFSVVGGKLSEGINFQDNLARAV 693
+++ K +F E+ SD+ ++S KGA LF+VVGGK+SEGINF D L RAV
Sbjct: 684 LKRIEEKKAVFTESRQPTSDVWDRFSRAA-KTSKGAILFAVVGGKMSEGINFCDELGRAV 742
Query: 694 VMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATIEFYENICMKAVNQSIGRAI 753
+++GLPYPN S EL + + ++ ++ + G L YE++CM AVNQ+IGRAI
Sbjct: 743 IVIGLPYPNKTSVELRERMKFLDTQMPNGGNLL----------YESLCMHAVNQAIGRAI 792
Query: 754 RHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKSELKTSEIFAQTSVFFASN 806
RH DYA +YL D+RY + KLS W+ R + +L EI +T FF +N
Sbjct: 793 RHRRDYAAVYLFDDRYAKESTRRKLSTWIGDRTQVKLGFGEIIRKTRSFFEAN 845
>7290134 [L] KOG1133 Helicase of the DEAD superfamily
Length = 861
Score = 342 bits (877), Expect = 1e-93
Identities = 256/870 (29%), Positives = 410/870 (46%), Gaps = 134/870 (15%)
Query: 3 KNFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREH---- 58
+ F PY PY+IQ QLM+ ++++L G+ VGIFESPTGTGK+L+L C +TWL H
Sbjct: 16 QEFGFPYSPYEIQEQLMQELFQVLERGQ-VGIFESPTGTGKSLTLTCGALTWLARHEELV 74
Query: 59 KLEKLNSKVDNDNLSDSTFSSSDDEPEWVNQFYNDKIMKEKSKSLQEYENYLEGLSMSNI 118
+ E L + S+ W+ + + + LQ + L+
Sbjct: 75 RTEMLARIRGVEQELAKLKEESEQSSNWLESQGKSRAQRAELLRLQHLQALLDKQEQQ-- 132
Query: 119 KPVLRQLDIGDRKRKKTVPRHIEIEIEDDETNFLPEPYEQDSVSNQNDYEKGQINDEIQK 178
L Q+ G +K K+ H ++E+ E + PE + DS D + D +
Sbjct: 133 ---LDQIRKGAKKHKRQGRVHPG-KLEELEKDLDPES-DSDSEHETADGPQEAAEDRYR- 186
Query: 179 LLAKIDKGYDVKTENNMELKSPLKIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIK 238
P++I+F SRTHSQL Q + ++
Sbjct: 187 ---------------------PVQIFFCSRTHSQLAQIVAELRKTPHG--------QSVR 217
Query: 239 FLPLASRKQLCIHAKVSKLKS-DLINDACVETV---------KRQECQFYTNSRDLISS- 287
+ L SR+QLC + V KLK L+N+ C++ K+ NSR +
Sbjct: 218 SISLGSRQQLCGNPAVRKLKHVGLMNERCLDMATKKARPNPSKKSRLTAEANSRCPFKAA 277
Query: 288 ---KQFRDYTFSEISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRES 344
+ RD +E DIE+L G + C YY+SR+A+E A+++ LPYQ +L R
Sbjct: 278 SLVESLRDLALTEPLDIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQ 337
Query: 345 LGINLKDSIVIIDEAHNLMDTITSIYSCEISLSDIK------------------------ 380
LGI+LK SIVI+DEAHNL+D++ ++ EIS ++
Sbjct: 338 LGISLKGSIVIVDEAHNLLDSVAQLHGSEISRQQLERAKVQISGYKDHFQKRFTTKNLLK 397
Query: 381 ------ICKKLMKIYLNKFKRKLNGKNRVNIMKL--------MKLLDILQAFIESHFEKG 426
I ++L+KI + + + NG + + +L + L ++L + F +
Sbjct: 398 INQIIFIIRRLLKILDQRKELQSNGCSMMRTYELTAEGDFFNIDLCELLDFCARTRFARK 457
Query: 427 KEISPQSMFRD----------SNADLLNIHELVTYMRGSKIAYKI-----DSYADSKLKS 471
+ M R+ S A L + L + + + + D + K +
Sbjct: 458 VQGRADRMEREPRPSENQAPVSTARSLILQRLASEQKLKEKTKSVKRRVEDINKEDKAEE 517
Query: 472 DESNTNSVKQPI-------LFKISKFVLSL-SNPXXXXXXXXXXXMIIKYMLLEPNQIFK 523
+ K+P+ + + F+ +L SN +KY+LL+P + F
Sbjct: 518 LQEQQKPTKKPVEEVAPSPIRPLLAFLETLTSNAEDGRILVDPVGGTLKYILLDPAEQFA 577
Query: 524 TIVNDSKCVILAGGTMQPTSEFIENLLPFVPSKDIVQFSCNHIIPESNLDTFIVSEG--- 580
IV +++ +++AGGTMQPT E E L + + +F NH++ + F++S G
Sbjct: 578 DIVAEARAIVIAGGTMQPTKELKEQLFTGCHDRLVERFY-NHVVANDAILPFVISNGPSG 636
Query: 581 --FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKFWQLEEIFEKL 638
+F + R + ++ +L L L VP G+V F PSY YL+ V K+ + E +
Sbjct: 637 APLSFKFAHRGSAEMLRELSMILRNLCQVVPGGVVCFLPSYEYLDKVYKYLEQSGTLETI 696
Query: 639 SMNKRIFYETPGGSD-ILPQYSSTILDKKK-GAFLFSVVGGKLSEGINFQDNLARAVVMV 696
S K +F E G ++ +L Y+ I GA L SVVGGKLSEG+NF D+L RAV++V
Sbjct: 697 SGRKSVFREVSGSAEQLLDNYALAIKRPASYGALLLSVVGGKLSEGLNFADDLGRAVLVV 756
Query: 697 GLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATIEFYENICMKAVNQSIGRAIRHA 756
GLPY N S EL + +H+++K+ G+ E+YEN+C+KAVNQ IGRA+RH
Sbjct: 757 GLPYSNSLSPELRQRMQHLDEKLGPGAGN---------EYYENLCVKAVNQCIGRAVRHI 807
Query: 757 NDYACIYLVDNRYLNNKVQHKLSEWVRKRV 786
DYAC+YL+D R+ + K++ KL +W+ + +
Sbjct: 808 KDYACVYLLDKRFADPKIRGKLPKWISRHI 837
>Hs13787200 [L] KOG1133 Helicase of the DEAD superfamily
Length = 856
Score = 335 bits (859), Expect = 2e-91
Identities = 264/896 (29%), Positives = 405/896 (44%), Gaps = 186/896 (20%)
Query: 4 NFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKL 63
+F P+ PY IQ M +Y +L +GK GIFESPTGTGK+LSLIC ++WLR+ + +K
Sbjct: 12 HFPFPFTPYSIQEDFMAELYRVLEAGKS-GIFESPTGTGKSLSLICGALSWLRDFEQKKR 70
Query: 64 NSKVD---------NDNLSDSTFSSSD-----------DEPEWVNQFYN--------DKI 95
+ +D +S SS EP WV QF D++
Sbjct: 71 EEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRL 130
Query: 96 MKEKSKSLQEYENYLEGLSMSNIKPVLRQLDIGDRKRKKTVPRHIEIEIEDDETNFLPEP 155
E+++ Q E + +K ++L + +R+ + E+ E L +
Sbjct: 131 KAEQARRKQREERLQQLQHRVQLKYAAKRLRQEEEERENLLRLSREMLETGPEAERLEQL 190
Query: 156 YEQDSVSNQNDYEKGQINDEIQKLLAKIDKGYDVKTENNMELKSPLKIYFSSRTHSQLTQ 215
+ +YE +DE +K+ +++D+ E+++E + KIY+ SRTHSQL Q
Sbjct: 191 ESGEEELVLAEYE----SDEEKKVASRVDED-----EDDLEEEHITKIYYCSRTHSQLAQ 241
Query: 216 FAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKS-DLINDACVETVK--- 271
F + ++ + L SR+ LC++ V L S LIND CV+ +
Sbjct: 242 FVHEVKKSPFG--------KDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRH 293
Query: 272 --------------RQE----CQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHV 313
RQE C FY + + + RD +E+ D+E L+ LG
Sbjct: 294 EKKKGAEEEKPKRRRQEKQAACPFYNHEQMGL----LRDEALAEVKDMEQLLALGKEARA 349
Query: 314 CPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCE 373
CPYY SR A+ A++V LPYQ +L R++ GI L+D +VIIDEAHNL+DTIT ++S E
Sbjct: 350 CPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVE 409
Query: 374 ISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKLMKLLDILQAFI-------------E 420
+S S + + Y+ ++ ++L K N+M L ++L +L+ F+ +
Sbjct: 410 VSGSQLCQAHSQLLQYVERYGKRLKAK---NLMYLKQILYLLEKFVAVLGGNIKQNPNTQ 466
Query: 421 SHFEKGKEISPQSMFR-DSNADLLNIHELVTYMRGSKIAYKIDSYADS------------ 467
S + G E+ + F S D +N+ ++ Y S I+ K+ + +
Sbjct: 467 SLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGAVFSSREQPK 526
Query: 468 -------------------KLKSDESNTNSVKQPI-LFKISKFVLSLSNP-----XXXXX 502
+DES ++++ L I F+ +L+
Sbjct: 527 LAGFQQFLQSLQPRTTEALAAPADESQASTLRPASPLMHIQGFLAALTTANQDGRVILSR 586
Query: 503 XXXXXXMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPF--VPSKDIVQ 560
+K++LL P F +V + + V++AGGTMQP S+F + LL V ++
Sbjct: 587 QGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSDFRQQLLACAGVEAERGGG 646
Query: 561 FSCNHIIPESNLDTFIVSEGFNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYG 620
C H+IP N+ ++ G
Sbjct: 647 VFCGHVIPPDNILPLVICSG---------------------------------------- 666
Query: 621 YLEHVIKFWQLEEIFEKLSMNKRIFYETPGG---SDILPQYSSTI------LDKKKGAFL 671
I LE F+K + + IF E +L YS I + GA L
Sbjct: 667 -----ISNQPLEFTFQKRELPQMIFQEPKSAHQVEQVLLAYSRCIQACGQERGQVTGALL 721
Query: 672 FSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKS 731
SVVGGK+SEGINF DNL R VVMVG+P+PN+ S+EL K +++Q + A G K+
Sbjct: 722 LSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPGQAPPGKA 781
Query: 732 ATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVK 787
EN+CMKAVNQSIGRAIRH D+A + L+D RY V KL W+R RV+
Sbjct: 782 ----LVENLCMKAVNQSIGRAIRHQKDFASVVLLDQRYARPPVLAKLPAWIRARVE 833
>Hs14765656 [L] KOG1133 Helicase of the DEAD superfamily
Length = 683
Score = 242 bits (618), Expect = 1e-63
Identities = 194/673 (28%), Positives = 308/673 (44%), Gaps = 130/673 (19%)
Query: 4 NFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKL 63
+F P+ PY IQ M +Y +L +GK +GIFESPTGTGK+LSLIC ++WLR+ + +K
Sbjct: 12 HFPFPFTPYSIQEDFMAELYRVLEAGK-IGIFESPTGTGKSLSLICGALSWLRDFEQKKR 70
Query: 64 NSKVD---------NDNLSDSTFSSSD-----------DEPEWVNQFYN--------DKI 95
+ +D +S SS EP WV QF D++
Sbjct: 71 EEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRL 130
Query: 96 MKEKSKSLQEYENYLEGLSMSNIKPVLRQLDIGDRKRKKTVPRHIEIEIEDDETNFLPEP 155
E+++ Q E + +K ++L R+ ++ + + E ET E
Sbjct: 131 KVEQARRKQREERLQQLQHRVQLKYAAKRL----RQEEEETENLLRLSREMLETGPEAER 186
Query: 156 YEQDSVSNQNDYEKGQINDEIQKLLAKIDKGYDVKTENNMELKSPLKIYFSSRTHSQLTQ 215
EQ + +DE +K+ +++D+ E+++E + KIY SRTHSQL Q
Sbjct: 187 LEQLESGEEELVLAEYESDEEKKVASRVDED-----EDDLEEEHITKIYHCSRTHSQLAQ 241
Query: 216 FAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKS-DLINDACVETVK--- 271
F + ++ + L SR+ LC++ V L S LIND CV+ +
Sbjct: 242 FVHEVKKSPFG--------KDVRLVSLGSRQNLCVNEDVRSLGSVQLINDRCVDMQRSRH 293
Query: 272 --------------RQE----CQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHV 313
RQE C FY + + + RD +E+ D+E L+ LG
Sbjct: 294 EKKKGAEEEKPKRRRQEKQAACPFYNHEQMGL----LRDEALAEVKDMEQLLALGKEARA 349
Query: 314 CPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCE 373
CPYY SR A+ A++V LPYQ +L R++ GI L+D +VIIDEAHNL+DTIT ++S E
Sbjct: 350 CPYYRSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVE 409
Query: 374 ISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKLMKLLDILQAFI-------------E 420
+S S + + Y+ ++ ++L K N+M L ++L +L+ F+ +
Sbjct: 410 VSGSQLCQAHSQLLQYMERYGKRLKAK---NLMYLKQILYLLEKFVAVLGGNIKQNPNTQ 466
Query: 421 SHFEKGKEISPQSMFR-DSNADLLNIHELVTYMRGSKIAYKIDSYADS------------ 467
S + G E+ + F S D +N+ ++ Y S I+ K+ + +
Sbjct: 467 SLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGAVFSSREQPK 526
Query: 468 -------------------KLKSDESNTNSVKQPI--LFKISKFVLSLSNP-----XXXX 501
+DES SV QP L I F+ +L+
Sbjct: 527 LAGFQQFLQSLQPRTTEALAAPADESQA-SVPQPASPLMHIEGFLAALTTANQDGRVILS 585
Query: 502 XXXXXXXMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPF--VPSKDIV 559
+K++LL P F +V + + V++AGGTMQP S+F + LL V ++ +V
Sbjct: 586 RQGSLSESTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSDFRQQLLACAGVEAERVV 645
Query: 560 QFSCNHIIPESNL 572
+FSC H+IP N+
Sbjct: 646 EFSCGHVIPPDNI 658
>ECU02g1090 [L] KOG1132 Helicase of the DEAD superfamily
Length = 678
Score = 202 bits (515), Expect = 1e-51
Identities = 193/654 (29%), Positives = 302/654 (45%), Gaps = 102/654 (15%)
Query: 176 IQKLLAKIDKGYDVKTENNMELKSPLKIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKE 235
I+ + AK +G K E E K LKI SRTH QL Q +
Sbjct: 67 IRGIGAKRREGGGPKGEEAREEK--LKIIICSRTHKQLDQLVDQLRKT----------QY 114
Query: 236 RIKFLPLASRKQLCIHAKVSKLKSDLINDACVETVKRQECQFYTNSRDLISSKQFRDYTF 295
R + LASR Q CI K+S + N C E VK C ++T +D ++ K
Sbjct: 115 RPRISILASRAQYCISPKLSDVADK--NTGCSELVKSGSCAYFTG-KDRLAKK-----VG 166
Query: 296 SEISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVI 355
+I DIE+L G CPYY+SR E AE++ PY +++ IRES GI+L++S+VI
Sbjct: 167 DKIFDIEELKGEGRRCVGCPYYASRILNEDAEVIFAPYNYLIDSRIRESTGISLENSVVI 226
Query: 356 IDEAHNLMDTITSIYSCEISLSDIKICKKLMKIYLNKFKRK-LNGKNRVNIMKLMKLLDI 414
+DEAHN+ D S S E+S +I + + L KR G+ R++ + LM
Sbjct: 227 VDEAHNIEDVCRSSGSIELSS---RIMEIIQNEILGAVKRSGALGEIRMDFVNLMDFFRK 283
Query: 415 LQAFIESHFE-------------KGKEISPQSMFRDSNADLLNI-HELVTYMRGSKIAYK 460
L+ ES E KG+EI + + + I E V ++ S Y
Sbjct: 284 LREGAESTDEFDRVTAGGKLRIRKGREIKEE-------LERMGIGKEFVLKIKNS--IYA 334
Query: 461 IDSYADSKLKSDESN------TNSVKQPILFK---ISKFVLSLSNPXXXXXXXXXXXMII 511
I D+K + S +SV I F FV N
Sbjct: 335 IQKSEDAKDLLNVSTFHVLEGLDSVLSAIHFSDCDAYSFVFHKMNDENVKNSRSCRFSY- 393
Query: 512 KYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENL---------LPFVPSKDIVQFS 562
+ LL+ F++ V + V+L GT+ P S F L P + ++ V S
Sbjct: 394 NFWLLDGGYTFRSFVGKVRSVVLLSGTLTPFSSFSSELGHEFAHTIVAPHLITQKQVFVS 453
Query: 563 C---NHIIPESNLDTFIVSEGFNFNYESRNNESVMCKLYDFLLELGCRVPH--GIVVFFP 617
C H++ E + T+ VS+ + +L ++++ C++ G +VF P
Sbjct: 454 CVRKGHLLKEL-IGTYGVSD----------TPQYLDQLCRVIVDVSCKIKDHGGTLVFVP 502
Query: 618 SYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSD---ILPQYSSTILDKKKGAFLFSV 674
SY +LE+ L++ +S + ++ G++ ++ +Y + I K+ F+ V
Sbjct: 503 SYSFLEN------LQKRMGGVSSGLLVEPKSGAGNEFEKVMRRYKNRIATKQSAVFM-CV 555
Query: 675 VGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATI 734
GK SEGI+F+D+ ARAV+ VG+PYP+L+ ++ +KK K S G L
Sbjct: 556 YRGKASEGIDFKDSFARAVIAVGIPYPSLHDPQVELKKE-FNDKYKSFNGRL-------- 606
Query: 735 EFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKS 788
+YE +AVNQ++GRAIRH +D+ + L+D+RY +VQ +LS+WV + +K+
Sbjct: 607 -WYEAQAFRAVNQALGRAIRHKDDWGIVMLLDSRYSEKRVQSQLSKWVAENIKT 659
>ECU08g1120 [L] KOG1133 Helicase of the DEAD superfamily
Length = 619
Score = 195 bits (496), Expect = 2e-49
Identities = 163/597 (27%), Positives = 289/597 (48%), Gaps = 83/597 (13%)
Query: 201 LKIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKS- 259
+K+ + +RTH+QLTQ + L SR+ C++ +V + +S
Sbjct: 73 MKVLYCTRTHTQLTQAINELKKLEAGCNS----------VVLGSRRIYCLNERVCQNRSS 122
Query: 260 DLINDACVETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHVCPYYSS 319
D +N+ C E VK C FY DL + D+EDLV +G + +CPYY S
Sbjct: 123 DAVNEGCKEAVKEGLCVFYDGC-DLFDGHG--------VLDVEDLVAMGRNERLCPYYVS 173
Query: 320 RTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCEISLSDI 379
+ + +IV LPYQ + + E R+S+ I++++SIV++DEAHN+ D++ + + I S +
Sbjct: 174 KRYSQQCDIVFLPYQLLFAREGRKSMDIDVRESIVVVDEAHNIYDSVVQMNTACILFSTM 233
Query: 380 KICKKLMKIYLNKFKRKLNGKNRVNIMKLMKLLDILQAFIESHFE---KGKEISPQSMF- 435
C K M++Y + R++ K + ++++L ++ F + + E +G+ + S F
Sbjct: 234 NRCIKAMQLYRERHGRRM--KREGQLETVVEILRRIKGFGDEYCEDVGEGEGVMGVSEFL 291
Query: 436 RDSNADLLNIHELVTYMRGSKIAYKIDSYADSKLKSDESNTNSVKQPILFKISKFVLSLS 495
+ + N+ E+ Y+ S I +++ + + S++ P +ISKF L L
Sbjct: 292 LKAGIEDFNMLEVEDYIVTSGIFRRLEGFGSNP---------SLQIP---EISKF-LGLL 338
Query: 496 NPXXXXXXXXXXXMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPFVPS 555
+++ L+ + F+ ++ + + ++LAGGTM+P ++ L+ +
Sbjct: 339 TVSDRSGRIFYSSRGVRFTPLDASMYFEDVL-ECRALLLAGGTMEP----VDQLMSVLGK 393
Query: 556 KDIVQFSCNHIIPESNLDTFIVSEG-----FNFNYESRNNESVMCKLYDFLLELGCRVPH 610
K FS + ++ +V G N+E+R + + + L V
Sbjct: 394 KSPRYFSYGSVC--NDFLALVVGSGPSGREIIVNFETRERPESIKDVTSSISNLSNAVKD 451
Query: 611 -GIVVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSDILPQYSSTILDKKKGA 669
G+V F PS YL L E + K+ YE D++ +
Sbjct: 452 GGMVCFLPSKAYL------GILRERCGDMVGTKKALYE-----DLITFEGYAEEAGRGPC 500
Query: 670 FLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDA 729
LF+V+GG+LSEG+NF D L R +V+VG+PYP + +L +K+R A
Sbjct: 501 ILFAVMGGRLSEGVNFGDGLCRLLVVVGVPYP---TQDLELKER---------------A 542
Query: 730 KSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRV 786
K E+ +I M+ VNQ++GRA+RH NDYA + L+D RY+ ++ +S W+R++V
Sbjct: 543 KFNGGEYATSIAMRTVNQTLGRALRHRNDYAVLVLLDKRYI--QLSRLVSPWIREKV 597
>7290625 [L] KOG1132 Helicase of the DEAD superfamily
Length = 985
Score = 181 bits (459), Expect = 4e-45
Identities = 173/655 (26%), Positives = 284/655 (42%), Gaps = 110/655 (16%)
Query: 202 KIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKSDL 261
K+ ++SRTHSQLTQ ++ + L SR QLCIH +V + + +
Sbjct: 108 KVIYASRTHSQLTQAMRELKRTAYA---------NMRSVVLGSRDQLCIHPEVMREQGNS 158
Query: 262 IN-DACVETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHVCPYYSSR 320
+ C V + C F S K D I DIEDLV++G L +CPY++SR
Sbjct: 159 NKTNMCKLRVHSKTCSFQMRVE---SRKDHPDLRGPTIMDIEDLVKVGQRLKICPYFASR 215
Query: 321 TALEGAEIVTLPYQHILSFEIR-------------------------ESLGINLKDSIVI 355
+ A+I +PY ++L + R ES + +K S V
Sbjct: 216 ELVPQADITFMPYNYLLDPKARKANKIELGNTIVILDEAHNIEKICEESASVQIKSSDVA 275
Query: 356 --IDEAHNLMDTITSIYSCEIS--------LSDIKICKKLMKIYLNKFKRKLNGKNRV-- 403
I++ ++M S S +++ L D+ + K+++ + L K + N V
Sbjct: 276 MAIEDVTHIMQVFASGESQDMAGDEPKDFTLDDLTLLKEML-LELEKAIDAIVVDNAVDG 334
Query: 404 --------------------NIMKLMKLLDILQAFIESHFEKGKEISPQSMFRDSNADLL 443
N+ ++ LLD L ++ ++ Q M
Sbjct: 335 TTFPASMMYELLGKANFTYGNVATIVSLLDKLVQYLL--------VASQQMSIRKGGTFT 386
Query: 444 NIHELVTYMRGSKIAYKIDSYADSKLKS--DESNTNSVKQPILFKISKFVLSLSNPXXXX 501
+ +L+T + +K YA K+ +ES KQ + ++
Sbjct: 387 LLSDLLTIVFANKEDVMSKVYASFKVHVLVEESKQGHGKQQGAKQQGGWLGK--GTIAAA 444
Query: 502 XXXXXXXMIIKYMLLEPNQIFKTIVNDS-KCVILAGGTMQPTSEFIENLLPFVPSKDIVQ 560
II + P + ++N + VIL GT+ P I L +P + Q
Sbjct: 445 TGLSKVAKIINFWCFNPGFGMEQLLNTQVRSVILTSGTLAPLKPLIAELA--IP---VAQ 499
Query: 561 FSCN-HIIPESNLDTFIVSEGFN-----FNYESRNNESVMCKLYDFLLELGCRVPHGIVV 614
N HI+ +S + I+ G + NY +R+N + L +L + VP G++V
Sbjct: 500 HLENPHIVDQSQVYVKIIGTGPDRQQLISNYANRDNPKYISSLGQTILNVARIVPDGLLV 559
Query: 615 FFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSDILPQYSSTI------LDKKKG 668
FFPSY L + WQ ++ +S K IF E P D Q++ST+ + KG
Sbjct: 560 FFPSYPMLNKCVDAWQASGLWADISCKKPIFLE-PRSKD---QFTSTMEEFYQAIRDSKG 615
Query: 669 AFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKD 728
A +V GK+SEG++F D RAV++ GLP+P L ++++K+R++E A + ++
Sbjct: 616 AVFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDPKVILKRRYLE-----ANRTREN 670
Query: 729 AKSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVR 783
+ E+Y +AVNQ+IGR IRH NDY I L D+R+ + +LS+W+R
Sbjct: 671 QLLSGQEWYNLDATRAVNQAIGRVIRHRNDYGAILLCDSRFKDASQVQQLSKWIR 725
Score = 62.8 bits (151), Expect = 2e-09
Identities = 27/56 (48%), Positives = 37/56 (65%), Gaps = 1/56 (1%)
Query: 6 HHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLE 61
H P++PY +Q ME + L G G+ ESPTGTGKTLSL+CS++ W+R + E
Sbjct: 12 HFPFEPYPVQRAYMEKVIHCLRDGTN-GVLESPTGTGKTLSLLCSSLAWIRTRQSE 66
>CE28992 [KL] KOG1131 RNA polymerase II transcription initiation/nucleotide
excision repair factor TFIIH 5'-3' helicase subunit RAD3
Length = 751
Score = 152 bits (384), Expect = 2e-36
Identities = 145/596 (24%), Positives = 261/596 (43%), Gaps = 68/596 (11%)
Query: 242 LASRKQLCIHAKVSKLK-SDLINDACVETVKRQECQFYTNSRDLISSKQFRDYTFSEI-- 298
+++RK LC++ V+ L+ + ++ AC + Q L + F ++ +
Sbjct: 109 MSARKNLCVNEPVAALRFGNTVDSACQKLTASSARQKRAEDPTLEACDYFENFEAKSVPM 168
Query: 299 SDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINL-KDSIVIID 357
+ EDL LG +CPY+++R A+ A IV Y +IL +I E + + + S+V+ D
Sbjct: 169 QNGEDLRSLGREKKICPYFTARQAINRAHIVVYSYHYILDPKIAELVSKDFSRKSVVVFD 228
Query: 358 EAHNLMDTITSIYSCEISLSDI-KICKKLMKI--YLNKFKRKLNGKNRVNIMKLMKLLDI 414
EAHN+ + S IS + + ++L + +N+ K + K + KL++ L
Sbjct: 229 EAHNIDNVCIESMSVAISQKNADRALQELQSLEGVVNRMKSSNSEKLQSEYDKLVEGLKR 288
Query: 415 LQAFIESHFEKGKEISPQSMF--------RDSNADLLNIHELVTYMRGSKIAYKIDSYAD 466
+ + + P + R +N LL + V Y+R +++ +
Sbjct: 289 TERERANDERLANPVLPDQILHEAVPGNIRQANHFLLFLKRFVEYIRHRLRTHQVLIESP 348
Query: 467 SKLKSDESNTNSV-KQPILF---KISKFVLSLS-----NPXXXXXXXXXXXMIIKY---- 513
+ D + + ++P+ F ++S V +L + ++ Y
Sbjct: 349 AAFMKDILDRMCIERKPMRFCAERLSNLVKTLEITDNGDVWALSQVTTLCTLVSTYSKGF 408
Query: 514 -MLLEPNQ----------------IFKTIVNDSKCVILAGGTMQPTSEFIENLLPFVPSK 556
+++EP + +++ + VI+ GT+ P E +L F PS
Sbjct: 409 SVIVEPQDGSQLAVITLSCHDASIAIRPVMSRFQSVIITSGTLSPL-EMYPKVLDFDPS- 466
Query: 557 DIVQFSCNHIIPESNLDTFIVSEG-----FNFNYESRNNESVMCKLYDFLLELGCRVPHG 611
V S + L +V+ G +E R + +V+ + +LE+ VP G
Sbjct: 467 --VIASFTMTLARPCLSPLVVARGNDQVAMTSRFEQRADVAVIRNYGNLVLEMASLVPDG 524
Query: 612 IVVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGG---SDILPQYSSTILDKKKG 668
+VVFF SY Y+E+VI W + I ++L K +F ET S L +Y D +G
Sbjct: 525 MVVFFTSYLYMENVIGVWYEQHIIDELMKYKLLFIETNDALETSAALEKYVEA-CDSGRG 583
Query: 669 AFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKD 728
A LFSV GK+SEGI+F +L R V+M+G+PY S L + ++ + +K+
Sbjct: 584 AVLFSVARGKVSEGIDFSHHLGRCVIMLGIPYMYTESRVLRARLEYLRDQF-----GIKE 638
Query: 729 AKSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRK 784
T + M+ Q +GRA+R DY + D R+ N + KL W+++
Sbjct: 639 NDFLTFD-----AMRHTAQCMGRALRSKTDYGLMVFADKRFSRNDKRGKLPRWMQE 689
>SPAC1D4.12 [KL] KOG1131 RNA polymerase II transcription initiation/nucleotide
excision repair factor TFIIH 5'-3' helicase subunit RAD3
Length = 772
Score = 151 bits (382), Expect = 3e-36
Identities = 148/652 (22%), Positives = 277/652 (41%), Gaps = 86/652 (13%)
Query: 202 KIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKSDL 261
K+ + SRT S++ + +E L L SRK LC+H V + K+
Sbjct: 68 KLIYCSRTMSEIDKALAELKRLMAYRTSQLGYEEPFLGLGLTSRKNLCLHPSVRREKNGN 127
Query: 262 INDACVET-----VKRQE--------CQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLG 308
+ DA + V+ Q C+F+ N DL + ++ ++D+ + G
Sbjct: 128 VVDARCRSLTAGFVREQRLAGMDVPTCEFHDNLEDLEPHSLISNGVWT----LDDITEYG 183
Query: 309 HSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINL-KDSIVIIDEAHNLMDTIT 367
CPY++ R L ++ Y ++L +I E + L KD IV+ DEAHN+ +
Sbjct: 184 EKTTRCPYFTVRRMLPFCNVIIYSYHYLLDPKIAERVSRELSKDCIVVFDEAHNIDNVCI 243
Query: 368 SIYSCEISLSDI-KICKKLMKIY--LNKFKRKLNGKNRVNIMKLMKLLDILQAFIESHFE 424
S +++ S + K K ++ + +N+ K+ + K + KL++ L A +
Sbjct: 244 ESLSIDLTESSLRKASKSILSLEQKVNEVKQSDSKKLQDEYQKLVRGLQDANAANDEDQF 303
Query: 425 KGKEISPQSMFRDSNADLLN--------IHELVTYMRGS-KIAYKIDSYADSKLKSDESN 475
+ P+ + +++ + + V Y++ K+ + I S L+ +
Sbjct: 304 MANPVLPEDVLKEAVPGNIRRAEHFIAFLKRFVEYLKTRMKVLHVIAETPTSFLQHVKDI 363
Query: 476 TNSVKQPILF---KISKFVLSLSNPXXXXXXXXXXXM----------------------- 509
T K+P+ F +++ V +L +
Sbjct: 364 TFIDKKPLRFCAERLTSLVRALQISLVEDFHSLQQVVAFATLVATYERGFILILEPFETE 423
Query: 510 -------IIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPFVPSKDIVQFS 562
I+++ L+ + K + + VI+ GT+ P + +L F ++Q S
Sbjct: 424 NATVPNPILRFSCLDASIAIKPVFERFRSVIITSGTLSPLDMY-PKMLQF---NTVMQES 479
Query: 563 CNHIIPESNLDTFIVSEG-----FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFP 617
+ + +V+ G + +E+RN+ SV+ + L+E P G+V FFP
Sbjct: 480 YGMSLARNCFLPMVVTRGSDQVAISSKFEARNDPSVVRNYGNILVEFSKITPDGLVAFFP 539
Query: 618 SYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSD---ILPQYSSTILDKKKGAFLFSV 674
SY YLE ++ WQ I +++ K I ETP + L Y + +GA L SV
Sbjct: 540 SYLYLESIVSSWQSMGILDEVWKYKLILVETPDPHETTLALETYRAA-CSNGRGAVLLSV 598
Query: 675 VGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATI 734
GK+SEG++F + RAV+M G+PY Y+ ++K R + + +++A T
Sbjct: 599 ARGKVSEGVDFDHHYGRAVIMFGIPYQ--YTESRVLKAR---LEFLRDTYQIREADFLTF 653
Query: 735 EFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRV 786
+ M+ Q +GR +R +D+ + L D RY + + KL +W+++ +
Sbjct: 654 D-----AMRHAAQCLGRVLRGKDDHGIMVLADKRYGRSDKRTKLPKWIQQYI 700
>YER171w [KL] KOG1131 RNA polymerase II transcription initiation/nucleotide
excision repair factor TFIIH 5'-3' helicase subunit RAD3
Length = 778
Score = 142 bits (359), Expect = 2e-33
Identities = 153/684 (22%), Positives = 279/684 (40%), Gaps = 114/684 (16%)
Query: 202 KIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSK-LKSD 260
KI + SRT S++ + +E + L L SRK LC+H +VSK K
Sbjct: 68 KIIYCSRTMSEIEKALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPEVSKERKGT 127
Query: 261 LINDACVETVKRQE--------------CQFYTNSRDLISSKQFRDYTFSEISDIEDLVQ 306
++++ C Q C+++ N ++ + DY + E L++
Sbjct: 128 VVDEKCRRMTNGQAKRKLEEDPEANVELCEYHENLYNI----EVEDYLPKGVFSFEKLLK 183
Query: 307 LGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINL-KDSIVIIDEAHNLMDT 365
+CPY+ R + I+ Y ++L +I E + + KDSIVI DEAHN+ +
Sbjct: 184 YCEEKTLCPYFIVRRMISLCNIIIYSYHYLLDPKIAERVSNEVSKDSIVIFDEAHNIDNV 243
Query: 366 ITSIYSCEISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKLMK--------------L 411
S +++ ++ + N +++ +V+ KL L
Sbjct: 244 CIESLSLDLTTDALRRATR----GANALDERISEVRKVDSQKLQDEYEKLVQGLHSADIL 299
Query: 412 LDILQAFIESHFEKGKEISPQSMFRDSNADLLN--------IHELVTYMRGS-KIAYKID 462
D + F+E+ + PQ + ++ + + L+ Y++ K+ + I
Sbjct: 300 TDQEEPFVET------PVLPQDLLTEAIPGNIRRAEHFVSFLKRLIEYLKTRMKVLHVIS 353
Query: 463 SYADSKLKSDESNTNSVKQPILF---KISKFVLSLS-----NPXXXXXXXXXXXMIIKY- 513
S L+ + T ++P+ F ++S V +L + +I Y
Sbjct: 354 ETPKSFLQHLKQLTFIERKPLRFCSERLSLLVRTLEVTEVEDFTALKDIATFATLISTYE 413
Query: 514 ----MLLEPNQI--------------------FKTIVNDSKCVILAGGTMQPTSEFIENL 549
+++EP +I K + VI+ GT+ P + +
Sbjct: 414 EGFLLIIEPYEIENAAVPNPIMRFTCLDASIAIKPVFERFSSVIITSGTISPLDMY-PRM 472
Query: 550 LPFVPSKDIVQFSCNHIIPESNLDTFIVSEG-----FNFNYESRNNESVMCKLYDFLLEL 604
L F K ++Q S + + + I+++G + +E RN+ S++ L+E
Sbjct: 473 LNF---KTVLQKSYAMTLAKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLVEF 529
Query: 605 GCRVPHGIVVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSD---ILPQYSST 661
P G+VVFFPSY Y+E ++ WQ I +++ +K I ETP + L Y
Sbjct: 530 AKITPDGMVVFFPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDAQETSLALETYRKA 589
Query: 662 ILDKKKGAFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVIS 721
+GA L SV GK+SEGI+F R V+M+G+P+ Y+ ++K R +
Sbjct: 590 -CSNGRGAILLSVARGKVSEGIDFDHQYGRTVLMIGIPFQ--YTESRILKARLEFMR--- 643
Query: 722 AGGSLKDAKSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEW 781
++ + +F M+ Q +GR +R +DY + L D R+ + Q L +W
Sbjct: 644 -----ENYRIRENDFLSFDAMRHAAQCLGRVLRGKDDYGVMVLADRRFSRKRSQ--LPKW 696
Query: 782 VRKRVKS---ELKTSEIFAQTSVF 802
+ + + L T + T F
Sbjct: 697 IAQGLSDADLNLSTDMAISNTKQF 720
>Hs15834617 [KL] KOG1131 RNA polymerase II transcription initiation/nucleotide
excision repair factor TFIIH 5'-3' helicase subunit RAD3
Length = 760
Score = 132 bits (332), Expect = 2e-30
Identities = 138/620 (22%), Positives = 258/620 (41%), Gaps = 82/620 (13%)
Query: 233 EKERIKFLPLA--SRKQLCIHAKVSKLKSDL-INDACVETVKRQECQFYTNSRDLISSKQ 289
E E++ FL LA SRK LCIH +V+ L+ ++ C Y + L +
Sbjct: 98 EGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRF 157
Query: 290 FRDYTF--------SEISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEI 341
+ ++ + I +++DL LG CPY+ +R ++ A +V Y ++L +I
Sbjct: 158 YEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKI 217
Query: 342 RESLGINL-KDSIVIIDEAHNLMDTITSIYSCEISLSDIKIC----KKLMKIYLNKFKRK 396
+ + L + ++V+ DEAHN+ + S ++ + C + L K L + K
Sbjct: 218 ADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVL-RIKET 276
Query: 397 LNGKNRVNIMKLMKLLDILQAFIESHFEKGKEISPQSMFRDSNADLLN--------IHEL 448
+ R +L++ L A E+ + P + +++ + + L
Sbjct: 277 DEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRL 336
Query: 449 VTYMRGS-KIAYKIDSYADSKLKSDESNTNSVKQPILFKISKF--------VLSLSNPXX 499
+ Y++ ++ + + + L ++P+ F + + L++
Sbjct: 337 LEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSP 396
Query: 500 XXXXXXXXXMIIKY-----MLLEP---------NQIFKTIVNDSKCVI-----------L 534
++ Y +++EP N I D+ I +
Sbjct: 397 LTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVII 456
Query: 535 AGGTMQPTSEFIENLLPFVPSKDIVQFSCNHIIPESNLDTFIVSEG-----FNFNYESRN 589
GT+ P + +L F P + + + L I+ G + +E+R
Sbjct: 457 TSGTLSPL-DIYPKILDFHP---VTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETRE 512
Query: 590 NESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETP 649
+ +V+ + LLE+ VP GIV FF SY Y+E + W + I E + NK +F ET
Sbjct: 513 DIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQ 572
Query: 650 GGSD---ILPQYSSTILDKKKGAFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSS 706
G++ L +Y + +GA L SV GK+SEGI+F + RAV+M G+PY +Y+
Sbjct: 573 DGAETSVALEKYQEA-CENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPY--VYTQ 629
Query: 707 ELLVKKRHIEQKVISAGGSLKDAKSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVD 766
++K R + + +++ T + M+ Q +GRAIR DY + D
Sbjct: 630 SRILKAR---LEYLRDQFQIRENDFLTFD-----AMRHAAQCVGRAIRGKTDYGLMVFAD 681
Query: 767 NRYLNNKVQHKLSEWVRKRV 786
R+ + KL W+++ +
Sbjct: 682 KRFARGDKRGKLPRWIQEHL 701
>7291258 [KL] KOG1131 RNA polymerase II transcription initiation/nucleotide
excision repair factor TFIIH 5'-3' helicase subunit RAD3
Length = 745
Score = 129 bits (325), Expect = 1e-29
Identities = 144/617 (23%), Positives = 262/617 (42%), Gaps = 92/617 (14%)
Query: 240 LPLASRKQLCIHAKVSK-------------LKSDLINDACVETVKRQECQFYTNSRDLIS 286
L L+SRK +CIH +VSK L + I + + CQ++
Sbjct: 83 LVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRERHEMDTETPICQYFEGF----- 137
Query: 287 SKQFRDYTFSE-ISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESL 345
S + ++ T + I+DL + G S + CPY+ +R A+ A IV Y ++L +I + +
Sbjct: 138 SLEGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVV 197
Query: 346 GINL-KDSIVIIDEAHNLMDTITSIYSCEISLSDIKICKKLMKIYLNKFKRKLNGK--NR 402
+ ++S V+ DEAHN+ + S +I+ ++ + +L K + + + NR
Sbjct: 198 SKEMSRESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTNALN-HLTKLVQDIREEDTNR 256
Query: 403 VN--IMKLMKLLDILQAFIESHFEKGKEISPQSMFRD------SNAD--LLNIHELVTYM 452
+N ++++ L ++ + P + + NAD L + + Y+
Sbjct: 257 LNEEYQRMVQGLKDASVQRDTDMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEYI 316
Query: 453 RGS-KIAYKIDSYADSKLKSDESNTNSVKQPILFKISKF--------VLSLSNPXXXXXX 503
+ ++ + + LK S ++P+ F + + L+
Sbjct: 317 KTRLRVHHVVQESPAGFLKDISSKICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLI 376
Query: 504 XXXXXMIIKY-----MLLEP---------NQIFKTIVNDS-----------KCVILAGGT 538
++ Y +++EP N I DS + V++ GT
Sbjct: 377 THFATLVSTYTKGFTIIIEPFDDKTPTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGT 436
Query: 539 MQPTSEFIENLLPFVPSKDIVQFSCNHIIPESNLDTFIVSEG-----FNFNYESRNNESV 593
+ P + +L F P +V S + L IVS+G + +E+R + +V
Sbjct: 437 LSP-MDMYPKILDFDP---VVMSSFTMTLARPCLLPMIVSKGNDQVTISSKFETREDTAV 492
Query: 594 MCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSD 653
+ L+E+ VP GIV FF SY YLE V+ W + I + L K +F ET ++
Sbjct: 493 IRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIETQDNAE 552
Query: 654 ---ILPQYSSTILDKKKGAFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLV 710
L Y D +GA L +V GK+SEG++F + RAV+M G+PY +Y+ ++
Sbjct: 553 TSYALMNYVKA-CDCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPY--VYTQSRIL 609
Query: 711 KKRHIEQKVISAGGSLKDA-KSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRY 769
K R L+D + +F M+ Q +GRA+R DY + D R+
Sbjct: 610 KARL---------DYLRDQFQIRENDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRF 660
Query: 770 LNNKVQHKLSEWVRKRV 786
+ + +L +W+++ +
Sbjct: 661 SRHDKRSRLPKWIQEHL 677
>Hs14042978 [L] KOG1132 Helicase of the DEAD superfamily
Length = 1249
Score = 129 bits (323), Expect = 2e-29
Identities = 121/496 (24%), Positives = 210/496 (41%), Gaps = 76/496 (15%)
Query: 2 GKNFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLRE---- 57
G + PY+ Y Q +M I LNS K+ + ESPTG+GK+L+L+CS + W +
Sbjct: 12 GVKIYFPYKAYPSQLAMMNSILRGLNS-KQHCLLESPTGSGKSLALLCSALAWQQSLSGK 70
Query: 58 --------------------HKLEKLNSKVDNDNLS------------DSTFSSSDDEPE 85
H + N+ ++ + T S+ D PE
Sbjct: 71 PADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNGTSSTCQDSPE 130
Query: 86 WVNQFYNDKIMKEKSKSLQEYENYLEGLSMSNIKPVLRQLDIGDRKRKKTVPRHIEIEIE 145
K+ +K S+ EN + I+P+ I R T +++ +++
Sbjct: 131 KTT--LAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEVHNLDAKVD 188
Query: 146 DDETNFLPEPYEQDSVSNQNDYEKGQINDEIQKLLAKIDKGYDVKTENNMEL----KSPL 201
+T L P E+ N + + + +G ++ N ++ KS +
Sbjct: 189 SGKTVKLNSPLEKI-----NSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKI 243
Query: 202 -KIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKSD 260
KIYF +RTH Q+ Q + L+SR C+H +V + +
Sbjct: 244 PKIYFGTRTHKQIAQITRELRRTAYSG---------VPMTILSSRDHTCVHPEV--VGNF 292
Query: 261 LINDACVETV---KRQECQFYTNSRDLISSKQFRDYTFSEIS---DIEDLVQLGHSLHVC 314
N+ C+E + + C FY + S Q TF + DIE+LV LG L C
Sbjct: 293 NRNEKCMELLDGKNGKSCYFYHGVHKI--SDQHTLQTFQGMCKAWDIEELVSLGKKLKAC 350
Query: 315 PYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCEI 374
PYY++R ++ A+I+ PY ++L +IRES+ +NLK+ +VI+DEAHN+ D S +
Sbjct: 351 PYYTARELIQDADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSV 410
Query: 375 SLSDIKICK-KLMKIYLNKFKRKLNGKNRVNIMKLMKLLDI-LQAFIESHFEKGKEISPQ 432
+ ++ + +L + N ++K + R L+ L+ + +E +E +I
Sbjct: 411 TEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKI--- 467
Query: 433 SMFRDSNADLLNIHEL 448
N LL +H++
Sbjct: 468 ---WSGNEMLLTLHKM 480
Score = 124 bits (311), Expect = 6e-28
Identities = 88/293 (30%), Positives = 149/293 (50%), Gaps = 26/293 (8%)
Query: 510 IIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENL-LPFVPSKDIVQFSCNHIIP 568
++ + L P F I + ++L GT+ P F L + F +Q NHII
Sbjct: 588 VLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFT-----IQLEANHIIK 642
Query: 569 ESNLDTFIVS---EGFNFNYESRNNESV--MCKLYDFLLELGCRVPHGIVVFFPSYGYLE 623
S + + +G N +N E+ ++ LL + V GI+ F PSY LE
Sbjct: 643 NSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLE 702
Query: 624 HVIKFWQLEEIFEKLSMNKRIFYETPGGS-----DILPQYSSTILDK--KKGAFLFSVVG 676
+ + W ++ L + K + E GG ++L Y I K K GA L +V
Sbjct: 703 KLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCR 762
Query: 677 GKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATIEF 736
GK+SEG++F D+ ARAV+ +G+P+PN+ ++ +K+++ + G L + ++
Sbjct: 763 GKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRG--LLPGR----QW 816
Query: 737 YENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQH--KLSEWVRKRVK 787
YE +A+NQ++GR IRH ND+ + LVD+R+ NN ++ LS+WVR++++
Sbjct: 817 YEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQ 869
>Hs7706541_1 [L] KOG1132 Helicase of the DEAD superfamily
Length = 755
Score = 127 bits (318), Expect = 9e-29
Identities = 85/307 (27%), Positives = 140/307 (44%), Gaps = 22/307 (7%)
Query: 510 IIKYMLLEPNQIFKTIVNDS-KCVILAGGTMQPTSEF-IENLLPFVPSKDIVQFSCNHII 567
++ Y P +V + +IL GT+ P S F +E +PF V HII
Sbjct: 452 VLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFP-----VCLENPHII 506
Query: 568 PESNLDTFIVSEG-----FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYL 622
+ + +V G + ++ R +E + L L + VP+G+++FFPSY +
Sbjct: 507 DKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVM 566
Query: 623 EHVIKFWQLEEIFEKLSMNKRIFYETPG----GSDILPQYSSTILDKKKGAFLFSVVGGK 678
E ++FW+ ++ K+ K +F E I Y+ GA +V GK
Sbjct: 567 EKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGK 626
Query: 679 LSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVIS--AGGSLKDAKSATIEF 736
SEG++F D R V++ GLPYP +++K + +++ AGG + E+
Sbjct: 627 ASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQ----EW 682
Query: 737 YENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKSELKTSEIF 796
Y +AVNQ+IGR IRH DY ++L D+R+ + +L WVR V+ +
Sbjct: 683 YRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVI 742
Query: 797 AQTSVFF 803
+ FF
Sbjct: 743 RDVAQFF 749
Score = 105 bits (262), Expect = 3e-22
Identities = 65/179 (36%), Positives = 92/179 (51%), Gaps = 15/179 (8%)
Query: 202 KIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKSDL 261
KI ++SRTHSQLTQ R K L SR+QLCIH +V K +S+
Sbjct: 108 KIIYASRTHSQLTQVINELRNTSY----------RPKVCVLGSREQLCIHPEVKKQESNH 157
Query: 262 IN-DACVETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHVCPYYSSR 320
+ C + V + C FY N + K S I DIEDLV+ G VCPYY SR
Sbjct: 158 LQIHLCRKKVASRSCHFYNN----VEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSR 213
Query: 321 TALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCEISLSDI 379
+ A+I+ +PY ++L + R + I+LK ++VI DEAHN+ S +++ D+
Sbjct: 214 NLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDL 272
Score = 57.0 bits (136), Expect = 1e-07
Identities = 29/65 (44%), Positives = 40/65 (60%), Gaps = 2/65 (3%)
Query: 2 GKNFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLE 61
G P+QPY Q + M + E L K GI ESPTGTGKTL L+C+T+ W REH +
Sbjct: 8 GVTVDFPFQPYKCQQEYMTKVLECLQQ-KVNGILESPTGTGKTLCLLCTTLAW-REHLRD 65
Query: 62 KLNSK 66
++++
Sbjct: 66 GISAR 70
>Hs14790174_1 [L] KOG1132 Helicase of the DEAD superfamily
Length = 766
Score = 127 bits (318), Expect = 9e-29
Identities = 85/307 (27%), Positives = 140/307 (44%), Gaps = 22/307 (7%)
Query: 510 IIKYMLLEPNQIFKTIVNDS-KCVILAGGTMQPTSEF-IENLLPFVPSKDIVQFSCNHII 567
++ Y P +V + +IL GT+ P S F +E +PF V HII
Sbjct: 452 VLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFP-----VCLENPHII 506
Query: 568 PESNLDTFIVSEG-----FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYL 622
+ + +V G + ++ R +E + L L + VP+G+++FFPSY +
Sbjct: 507 DKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVM 566
Query: 623 EHVIKFWQLEEIFEKLSMNKRIFYETPG----GSDILPQYSSTILDKKKGAFLFSVVGGK 678
E ++FW+ ++ K+ K +F E I Y+ GA +V GK
Sbjct: 567 EKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGK 626
Query: 679 LSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVIS--AGGSLKDAKSATIEF 736
SEG++F D R V++ GLPYP +++K + +++ AGG + E+
Sbjct: 627 ASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQ----EW 682
Query: 737 YENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKSELKTSEIF 796
Y +AVNQ+IGR IRH DY ++L D+R+ + +L WVR V+ +
Sbjct: 683 YRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVI 742
Query: 797 AQTSVFF 803
+ FF
Sbjct: 743 RDVAQFF 749
Score = 105 bits (262), Expect = 3e-22
Identities = 65/179 (36%), Positives = 92/179 (51%), Gaps = 15/179 (8%)
Query: 202 KIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKSDL 261
KI ++SRTHSQLTQ R K L SR+QLCIH +V K +S+
Sbjct: 108 KIIYASRTHSQLTQVINELRNTSY----------RPKVCVLGSREQLCIHPEVKKQESNH 157
Query: 262 IN-DACVETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHVCPYYSSR 320
+ C + V + C FY N + K S I DIEDLV+ G VCPYY SR
Sbjct: 158 LQIHLCRKKVASRSCHFYNN----VEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSR 213
Query: 321 TALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCEISLSDI 379
+ A+I+ +PY ++L + R + I+LK ++VI DEAHN+ S +++ D+
Sbjct: 214 NLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDL 272
Score = 57.0 bits (136), Expect = 1e-07
Identities = 29/65 (44%), Positives = 40/65 (60%), Gaps = 2/65 (3%)
Query: 2 GKNFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLE 61
G P+QPY Q + M + E L K GI ESPTGTGKTL L+C+T+ W REH +
Sbjct: 8 GVTVDFPFQPYKCQQEYMTKVLECLQQ-KVNGILESPTGTGKTLCLLCTTLAW-REHLRD 65
Query: 62 KLNSK 66
++++
Sbjct: 66 GISAR 70
>At1g79950 [L] KOG1132 Helicase of the DEAD superfamily
Length = 983
Score = 126 bits (316), Expect = 2e-28
Identities = 85/295 (28%), Positives = 144/295 (48%), Gaps = 26/295 (8%)
Query: 532 VILAGGTMQPTSEFIENLLPFVPSKDIVQFSCNHIIPESNLDTFIVSEG-----FNFNYE 586
+IL GT+ P + L P ++ H+I + L +VS G N +Y
Sbjct: 428 IILTSGTLSPMDSLAQELKLDFP----IRLENPHVISSNQLWAGVVSTGPSGYVLNSSYR 483
Query: 587 SRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKFWQ------LEEIFEKLSM 640
+R+ +L + ++ VP G+++FFPSY ++ I FW+ ++E++
Sbjct: 484 NRDVPEYKQELGNAIVNFSRVVPEGLLIFFPSYYLMDSCITFWKNGCYRNSMTVWERICK 543
Query: 641 NKRIFYETPGGSDILP----QYSSTILDKK-KGAFLFSVVGGKLSEGINFQDNLARAVVM 695
K+ E P S + P +S + D+ G F+V GK+SEG++F D RAVV+
Sbjct: 544 LKKPVIE-PKDSSLFPAAMRDFSEKLQDRATSGVVFFAVCRGKVSEGLDFADGAGRAVVI 602
Query: 696 VGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATIE---FYENICMKAVNQSIGRA 752
GLPY + + +K+ ++++ S +K +S + +Y +AVNQ+IGR
Sbjct: 603 TGLPYARVTDPRVKLKREFLDEQ--SQLADVKLPRSTLLSGSMWYSQEAARAVNQAIGRV 660
Query: 753 IRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKSELKTSEIFAQTSVFFASNR 807
IRH +DY I D+R+ Q K+S W+R VK + E+ + + FF + R
Sbjct: 661 IRHRHDYGAIIFCDDRFEQPSQQSKISLWIRPNVKCYSRYGEVISDLARFFRTER 715
Score = 79.0 bits (193), Expect = 3e-14
Identities = 42/128 (32%), Positives = 71/128 (54%), Gaps = 6/128 (4%)
Query: 238 KFLPLASRKQLCIHAKVSKLKSDLINDACVETVKRQ---ECQFYTNSRDLISSKQFRDYT 294
K + L SR+QLC++ +V+ L+ + +AC K++ +C + D + + +
Sbjct: 117 KMVVLGSREQLCVNEEVNSLRGKALTNACQYLCKKRGKRQCNHFNRLPDYL---KHNPHI 173
Query: 295 FSEISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIV 354
E DIEDLV +G CPYY +R + +I+ PY +++S R+ L +N +S++
Sbjct: 174 GDEPVDIEDLVNIGKDSGPCPYYITRELHKDVDIIFAPYNYLISNGYRKFLKVNWTNSVL 233
Query: 355 IIDEAHNL 362
I DEAHNL
Sbjct: 234 IFDEAHNL 241
>ECU06g0200 [KL] KOG1131 RNA polymerase II transcription initiation/nucleotide
excision repair factor TFIIH 5'-3' helicase subunit RAD3
Length = 742
Score = 124 bits (312), Expect = 4e-28
Identities = 84/278 (30%), Positives = 134/278 (47%), Gaps = 41/278 (14%)
Query: 532 VILAGGTMQPTSEFIENLLPFVPSKDIVQFSCNHIIPESNLDTFIVSEG----------- 580
VI+ GTM P + +L FVPS+ I + + +++ I+++G
Sbjct: 431 VIITSGTMSPIDMY-PKILNFVPSR-IAEIGAT--LDRNSISPLIITKGNDQMTLRALSD 486
Query: 581 ------------FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKF 628
++ R++ SV+ ++EL VP GIV FFPSY Y+E ++
Sbjct: 487 DMETTDACSGDVLTTSFSLRSDPSVVRNYGHLMVELSKVVPDGIVCFFPSYMYMEEIVSL 546
Query: 629 WQLEEIFEKLSMNKRIFYETPGGSD---ILPQYSSTILDKKKGAFLFSVVGGKLSEGINF 685
W I ++S NK +F ETP G + L Y D +G LFSV GK+SEG++F
Sbjct: 547 WAETSIINEISKNKLVFVETPDGRETELALANYKRA-CDNGRGGMLFSVARGKVSEGVDF 605
Query: 686 QDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATIEFYENICMKAV 745
+D R VVM+G+P+ Y+ + +KKR + +K+ T + M+
Sbjct: 606 EDGYGRCVVMLGVPFQ--YTESVRLKKR---LDFLREEYGIKEYDFLTFD-----AMRHA 655
Query: 746 NQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVR 783
Q +GR +R+ NDY + L D R+ N + KL +W+R
Sbjct: 656 AQCLGRVLRNKNDYGLMILADERFERNDKKSKLPKWIR 693
Score = 61.6 bits (148), Expect = 5e-09
Identities = 46/160 (28%), Positives = 75/160 (46%), Gaps = 13/160 (8%)
Query: 240 LPLASRKQLCIHAKVSKLKSDLINDAC---VETVKRQECQFYTNSRDLISSKQFRDYTFS 296
L L RK LCI+ + LKS ++ AC V + +C FY N D FR+ +
Sbjct: 107 LGLTGRKNLCINK--AALKSFNVDVACRRLVNKLAESKCDFYENLAD------FREVPVA 158
Query: 297 EISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINL-KDSIVI 355
+ D L ++G +CPYY R ++ + + PY +++ I + L +S+VI
Sbjct: 159 -VYDFLQLKEMGEKKGICPYYLVRRSIPVCDCIIYPYNYLIDPRICAIVSSELGPNSVVI 217
Query: 356 IDEAHNLMDTITSIYSCEISLSDIKICKKLMKIYLNKFKR 395
DEAHN+ + S EI + ++ + + N KR
Sbjct: 218 FDEAHNIDSHCIEVLSIEIRRNVLEGASRAIGNLENLLKR 257
>CE15894 [L] KOG1132 Helicase of the DEAD superfamily
Length = 994
Score = 119 bits (299), Expect = 1e-26
Identities = 82/313 (26%), Positives = 159/313 (50%), Gaps = 32/313 (10%)
Query: 509 MIIKYMLLEPNQIFKTI-VNDSKCVILAGGTMQPTSEFIENL-LPFVPSKDIVQFSCNHI 566
+ IKY + + + + + + V+LA GT+ P F N+ L F + H
Sbjct: 463 LTIKYFCFQASISMRMLKMRGVRNVLLASGTLSPIQAFTYNMGLNFGAILEN-----EHA 517
Query: 567 IPESNLDTFIVSEG----FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYL 622
+ + + T IV+ G ++++R N + + + LL + +P GI++FF SY +
Sbjct: 518 LKQVPVLTSIVTRGKRGGLAGSFQNRKNLDYVTGVAEALLRVMEVIPQGILIFFSSYSQM 577
Query: 623 EHVIKFWQL--------EEIFEKLSMNKRIFYETPGGSDILP---QYSSTILDKKKGAFL 671
+ ++ W+ E +EK+ KR+ E ++ +Y+ + ++ GA L
Sbjct: 578 DELVATWKTTKWSSNSNESFWEKMEKTKRVVVEPRAKEELAAIRLRYTQGV-SEQHGAAL 636
Query: 672 FSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKS 731
+V GK+SEGI+F D +RAV+++G+PYP ++ +++KK +++ + K +
Sbjct: 637 LAVCRGKVSEGIDFCDAESRAVIIIGIPYPPIHDERVVLKKMYLDD--LMGRKDTKSERQ 694
Query: 732 ATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKSE-- 789
++ ++Y+ +AVNQ+IGR +RH +D+ + L+D RY + K + +W+R +
Sbjct: 695 SSQDWYQMEAFRAVNQAIGRVLRHKDDFGTVVLMDTRYASAKPE-MFPKWLRNTISRSDT 753
Query: 790 ----LKTSEIFAQ 798
LKTS F +
Sbjct: 754 DGCALKTSRFFKE 766
Score = 107 bits (268), Expect = 6e-23
Identities = 67/199 (33%), Positives = 101/199 (50%), Gaps = 10/199 (5%)
Query: 190 KTENNMELKSPLKIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLC 249
KT+ ++ I+++SRTHSQL Q E + +K L SR+ C
Sbjct: 92 KTDEKLKSAYVPTIFYASRTHSQLEQVVHELNRT---------EYKWVKTTILGSREHFC 142
Query: 250 IHAKVSKLK-SDLINDACVETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLG 308
I+ KV K+K S+ C V ++ C +Y + K E DIED V+LG
Sbjct: 143 INQKVKKIKESNRQAHVCRGLVSKRACHYYNKFDACTTDKMTEFLDKGEAMDIEDFVKLG 202
Query: 309 HSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITS 368
+CPY+ SR E AE++ LPY +I+ ++R ++LK+SIVI DEAHNL S
Sbjct: 203 TQNSLCPYFMSRQRSETAELILLPYNYIIDPKMRRRYKLDLKNSIVIFDEAHNLESICES 262
Query: 369 IYSCEISLSDIKICKKLMK 387
S E++ + I +C + +K
Sbjct: 263 NASAELTSTSIALCIEELK 281
Score = 55.1 bits (131), Expect = 4e-07
Identities = 25/55 (45%), Positives = 38/55 (68%), Gaps = 1/55 (1%)
Query: 8 PYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEK 62
P++PY+ Q M+++ ++L+ K ESPTGTGKTLSL+CST+ W++ K K
Sbjct: 22 PFEPYECQRIFMKNVVDVLDR-KLDAALESPTGTGKTLSLLCSTLAWVQRQKETK 75
>CE17764 [L] KOG1132 Helicase of the DEAD superfamily
Length = 983
Score = 113 bits (283), Expect = 1e-24
Identities = 78/301 (25%), Positives = 141/301 (45%), Gaps = 33/301 (10%)
Query: 511 IKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPFVPSKDIVQFSCNHIIPES 570
I + P F N+++ ++LA GT+ P ++ L + + Q + +I +
Sbjct: 662 ISLWCMSPALSFFDAFNETRSIVLASGTLCP----MDTLKTELGMEFKQQVEGDQVINKD 717
Query: 571 NLDTFIVSEG-------FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLE 623
N+ ++ G + S S C+L + + VP GI+ F PSY L+
Sbjct: 718 NIFAAVLPIGPFGNRIQCTYRNTSDPESSFYCELGAIIKYVCSNVPAGILCFLPSYRVLD 777
Query: 624 HVIKFWQLEEIFEKLSMNKRIFYETPGGSD---ILPQYSSTILDKKK------GAFLFSV 674
+ + ++ M K + YE S+ ++ Q+ + I D + G+ +F+V
Sbjct: 778 QLKQCMIRNSTMRQIEMKKVVLYEPRRSSELTSVMDQFDAAIFDPSRFGANINGSLMFAV 837
Query: 675 VGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATI 734
GK+SEGI+F D+ AR V+ VG+PYPN ++ KK + +Q G D
Sbjct: 838 FRGKVSEGIDFADDRARVVISVGIPYPNAMDDQVNAKKLYNDQNSKEKGILTGD------ 891
Query: 735 EFYENICMKAVNQSIGRAIRHANDYACIYLVDNR-------YLNNKVQHKLSEWVRKRVK 787
E+Y +A+NQ++GR +RH ND+ + ++D R + ++S+W+R ++K
Sbjct: 892 EWYTTQAYRALNQALGRCLRHKNDWGAMLMIDERLERQTGNLVGGASSARVSKWIRAQLK 951
Query: 788 S 788
S
Sbjct: 952 S 952
Score = 79.3 bits (194), Expect = 2e-14
Identities = 97/402 (24%), Positives = 163/402 (40%), Gaps = 78/402 (19%)
Query: 12 YDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKLNSKVDNDN 71
Y Q ++ I L + + V + ESPTG+GKT++L+ ST WL+++ EK SK +
Sbjct: 91 YSTQKLMIVRILTALKNSQNV-LGESPTGSGKTMALLASTCAWLKQYIDEKRESK---EK 146
Query: 72 LSDSTFSSSDDEPEWVNQFYNDKIMKEKSKSLQE---YENYLEGLSMSNIKPVLRQL--D 126
FS F ND + +SK +E E ++E + + N K Q D
Sbjct: 147 CEIHGFSGKTQVV-----FTNDIGIPLESKVYEEPPEEEEFIEPVPVKNDKLFEAQWEHD 201
Query: 127 IGDRKRKKTVPRHIEIEIEDDETNFLPEPYEQDSVSNQNDYEKGQINDEIQKLLAKIDKG 186
+T P ++ E+E + PEP
Sbjct: 202 FTPHTPGETPPVTLKEELEPVKK---PEP------------------------------- 227
Query: 187 YDVKTENNMELKSPLKIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRK 246
E ++IY+ +RTH Q+ Q +K LASR+
Sbjct: 228 ----VETKCTCLPRVRIYYGTRTHKQIAQVVKEFSRLPYAKI--------LKHTILASRE 275
Query: 247 QLCIHAKVSKLKSDLINDACVETVKRQE--CQFYTNSRDLISSK-QFRDYTFSEISDIED 303
Q CI+ K I+ C E C F + + RD+ + + D
Sbjct: 276 QSCINPAARKHAD--ISQYCKEVNSAHSIGCSFKSAMKPRFEKALPLRDHLERNGTVVFD 333
Query: 304 LVQLGHSLHV-----CPYYSSRTAL-EGAEIVTLPYQHILSFEIRESLGINLKDSIVIID 357
+ ++ +L + CPY+S+ L + A+I+ P+ +++ IR S + +++SIVI+D
Sbjct: 334 MEKIVETLAISYPQLCPYFSTNRILTQDADIIFCPFSYLVDPLIRNSSDVQIRNSIVILD 393
Query: 358 EAHNLMDTITSIYS-------CEISLSDIKICKKLMKIYLNK 392
EAHN+ DT S + S+ ++I +K + L+K
Sbjct: 394 EAHNIEDTCREAASFSFTEKELDDSILSLRIKRKAVDTELDK 435
>At1g03190 [KL] KOG1131 RNA polymerase II transcription initiation/nucleotide
excision repair factor TFIIH 5'-3' helicase subunit RAD3
Length = 758
Score = 93.6 bits (231), Expect = 1e-18
Identities = 69/273 (25%), Positives = 121/273 (44%), Gaps = 23/273 (8%)
Query: 523 KTIVNDSKCVILAGGTMQPTSEFIENLLPFVPSKDIVQFSCNHIIPESNLDTFIVSEG-- 580
K + + + V++ GT+ P + LL F P +V S + + +++ G
Sbjct: 445 KPVFDRFQSVVITSGTLSPI-DLYPRLLNFTP---VVSRSFKMSMTRDCICPMVLTRGSD 500
Query: 581 ---FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKFWQLEEIFEK 637
+ ++ R++ V+ L+E+ VP G+V FF SY Y++ +I W I ++
Sbjct: 501 QLPVSTKFDMRSDPGVVRNYGKLLVEMVSIVPDGVVCFFVSYSYMDGIIATWNETGILKE 560
Query: 638 LSMNKRIFYETPGGSD---ILPQYSSTILDKKKGAFLFSVVGGKLSEGINFQDNLARAVV 694
+ K +F ET + L Y D +GA FSV GK++EGI+F + R VV
Sbjct: 561 IMQQKLVFIETQDVVETTLALDNYRRA-CDCGRGAVFFSVARGKVAEGIDFDRHYGRLVV 619
Query: 695 MVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATIEFYENICMKAVNQSIGRAIR 754
M G+P+ S L + ++ +K+ T + ++ Q +GR IR
Sbjct: 620 MYGVPFQYTLSKILRARLEYLHDTF-----QIKEGDFLTFD-----ALRQAAQCVGRVIR 669
Query: 755 HANDYACIYLVDNRYLNNKVQHKLSEWVRKRVK 787
DY + D RY + + KL W+ ++
Sbjct: 670 SKADYGMMIFADKRYSRHDKRSKLPGWILSHLR 702
Score = 62.4 bits (150), Expect = 3e-09
Identities = 52/229 (22%), Positives = 102/229 (43%), Gaps = 21/229 (9%)
Query: 199 SPLKIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLK 258
SP+K+ + +RT ++ + + +I L L+SRK LC++ KV +
Sbjct: 66 SPIKLVYCTRTVHEMEKTLGELKLLHDYQVRHLGTQAKILALGLSSRKNLCVNTKVLAAE 125
Query: 259 S-DLINDAC------------VETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLV 305
+ D ++ AC E + C F+ N + ++ +EDL
Sbjct: 126 NRDSVDAACRKRTASWVRALSTENPNVELCDFFENYEKAAENALLPPGVYT----LEDLR 181
Query: 306 QLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINL-KDSIVIIDEAHNLMD 364
G + CPY+ +R ++ A ++ YQ++L ++ + L K+S+V+ DEAHN+ +
Sbjct: 182 AFGKNRGWCPYFLARHMIQFANVIVYSYQYLLDPKVAGFISKELQKESVVVFDEAHNIDN 241
Query: 365 TITSIYSCEISLSDIK-ICKKLMKI--YLNKFKRKLNGKNRVNIMKLMK 410
S + ++ + L KI +++FK G+ R +L++
Sbjct: 242 VCIEALSVSVRRVTLEGANRNLNKIRQEIDRFKATDAGRLRAEYNRLVE 290
>At1g20750 [L] KOG1132 Helicase of the DEAD superfamily
Length = 1055
Score = 92.0 bits (227), Expect = 3e-18
Identities = 132/590 (22%), Positives = 228/590 (38%), Gaps = 119/590 (20%)
Query: 188 DVKTENNMELKSPL--KIYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASR 245
D+ +N+E P IY++SRTH+Q+TQ R+ L SR
Sbjct: 109 DIAGSSNVEPHEPQIPTIYYASRTHAQITQVIREYRKTGY----------RVPMTVLGSR 158
Query: 246 KQLCIHAKVSKLKSDLINDACVETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLV 305
K+ C ++ V ++ +++ C +++ + + + DIEDLV
Sbjct: 159 KRYCTNSHVQGKEN--VDEKC-------------GVGRILAYPSLQQTGHNGVHDIEDLV 203
Query: 306 QLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDT 365
++G ++ CPY++S LE A++V PY +I+ IR G+NL+ +I+I DEAHN+ D
Sbjct: 204 KIGKTVTGCPYFASWKMLEVAQLVFCPYSYIIDPVIRG--GVNLQGAIIIFDEAHNMEDI 261
Query: 366 ITSIYSCEISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKLMKLLDILQAFIESHFEK 425
S + DI + K K +L + V L ++++ I K
Sbjct: 262 AREAGSINLE-EDI----------IFKLKNELEQMSEVEPEIYDSLYEVVEGLISWIGRK 310
Query: 426 GKEISPQSM---FRDSNADLLNIHELVTYMRGSKIAYKIDSYADSKLKSDESNTNSVKQP 482
++ + + F + D + EL + + + + + + E+ +P
Sbjct: 311 KDSLAKRDVDHYFSNWTGDRA-LKELKEFNITRENFPNLKACFNQAITKSEAAEIDPDKP 369
Query: 483 ILFKISKFVLSLSNPXXXXXXXXXXXMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPT 542
L IS L N + P+ +FK + + S +IL GT+ P
Sbjct: 370 YLSGISVSTLEGDNGWTNT---------FSLWCMNPSVVFKDLADLSLSIILTSGTLSPM 420
Query: 543 SEFIENL-LPFVPSKDIVQ-FSCNHIIPESNLDTFIVSEGFNFNYESRNNESVMCKLYDF 600
+ F L + F + N + + T + N +Y + + L
Sbjct: 421 NSFSSELGMQFGTCLEAPHVIDPNMQVWAGAISTVPGNYPLNASYRTAEAYAFQDALGKS 480
Query: 601 LLELGCRVPHGIVVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSDILPQYSS 660
L E+ VP P G + L+E ++ +S R+ G + + + S
Sbjct: 481 LEEICTIVPE------PRGGSKDDFETV--LKEYYDSISGKNRLI----GRNSSVKKAGS 528
Query: 661 TIL----DKKKGAFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIE 716
I D K+G+ +V GK+SEG++F D+ ARAV
Sbjct: 529 VITEAQDDSKRGSAFLAVCRGKVSEGMDFSDDNARAV----------------------- 565
Query: 717 QKVISAGGSLKDAKSATIEFYENICMKAVNQSIGRAIRHANDY-ACIYLV 765
+A+NQ+ GR IRH DY A I+LV
Sbjct: 566 ------------------------AYRALNQAAGRCIRHRFDYGAIIFLV 591
Score = 62.4 bits (150), Expect = 3e-09
Identities = 38/118 (32%), Positives = 57/118 (48%), Gaps = 18/118 (15%)
Query: 2 GKNFHHPYQPYDIQTQLMEHIYELLNSGKKVG----IFESPTGTGKTLSLICSTVTWLRE 57
G PYQPY Q M + L+ ++ G + ESPTGTGK+LSL+CS + W +
Sbjct: 31 GLQVEFPYQPYGTQLAFMSRVISTLDRAQRDGHSHALLESPTGTGKSLSLLCSVLAWQKS 90
Query: 58 HKLEKLNSKVDNDNLSDSTFSSSD---------DEPEWVNQFYNDKIMKEKSKSLQEY 106
+K S+ N NLS S SD EP+ +Y + + ++ ++EY
Sbjct: 91 YK-----SRFPNGNLSHSKTQPSDIAGSSNVEPHEPQIPTIYYASRTHAQITQVIREY 143
>At1g20720 [L] KOG1132 Helicase of the DEAD superfamily
Length = 986
Score = 79.3 bits (194), Expect = 2e-14
Identities = 51/158 (32%), Positives = 79/158 (49%), Gaps = 25/158 (15%)
Query: 203 IYFSSRTHSQLTQFAXXXXXXXXXXXXXXXEKERIKFLPLASRKQLCIHAKVSKLKSDLI 262
IY++SRTHSQ+TQ R+ LASRK C + V L D +
Sbjct: 151 IYYASRTHSQITQVIREYRKTGY----------RVPMAVLASRKHYCTNRHV--LGKDNV 198
Query: 263 NDACVETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHVCPYYSSRTA 322
+D N + S + +E+ DIEDLV++G ++ CPY++S +
Sbjct: 199 DDEW-------------NVNKITSHPSLQPRGHNEVHDIEDLVKVGKNVRGCPYFASWSM 245
Query: 323 LEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAH 360
E A++V PY +I++ IR + ++LK +I+I DEAH
Sbjct: 246 AENAQLVFCPYSYIVNPVIRAGVEVDLKGAIIIFDEAH 283
Score = 75.5 bits (184), Expect = 3e-13
Identities = 74/277 (26%), Positives = 117/277 (41%), Gaps = 47/277 (16%)
Query: 516 LEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENL-LPFVPSKDIVQFSCNHII-PESNLD 573
+ P +FK + + S VIL GT+ P + F L + F S + H+I P +
Sbjct: 433 MNPAVVFKDLADISLSVILTSGTLSPMNSFSSELGMQFGTSLE-----APHVIDPNMQVW 487
Query: 574 TFIVSEG-----FNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKF 628
+S G N +Y++ + S L L E+ VP G +VFFPSY +E +
Sbjct: 488 AGAISNGPSNYPLNASYKTADAYSFQDALGKSLEEICTIVPGGSLVFFPSYKLMEKLCMR 547
Query: 629 WQLEEIFEKLSMNKRIFYETPGGS-----DILPQYSSTIL-------------------- 663
W+ E + +L + K +F E GG+ +L Y +I
Sbjct: 548 WRETEQWSRLCLKKDLFVEPRGGAQDEFDSVLKGYYDSIRGKNKIIGRNRRAKKAGPIKT 607
Query: 664 ----DKKKGAFLFSVVGGKLSEGINFQDNLARAVV----MVGLPYPNLYSSELLVKKRHI 715
D KKGA +V GK+SEGI+F D+ ARAVV Y +Y S+ R +
Sbjct: 608 ETQDDSKKGAAFLAVCRGKVSEGIDFADDNARAVVEDYTNSNPKYHFMYESKAFGYHRDV 667
Query: 716 EQKVISAGGSLKDAKSATIEFYE--NICMKAVNQSIG 750
+ K+ S+ + ++ E C + ++ G
Sbjct: 668 KPKIAEDLRSMGHSAQTFVQVKEEAECCREVIDLECG 704
Score = 55.1 bits (131), Expect = 4e-07
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 9/78 (11%)
Query: 2 GKNFHHPYQPYDIQTQLMEHIYELLNSGKKVG----IFESPTGTGKTLSLICSTVTWLRE 57
G PYQPY Q M + L+ ++ G + ESPTGTGK+LSL+CS + W +
Sbjct: 31 GLQVEFPYQPYGTQLAFMSRVISTLDRAQRDGHCHALLESPTGTGKSLSLLCSVLAWQQN 90
Query: 58 HKLEKLNSKVDNDNLSDS 75
+K S++ NLS S
Sbjct: 91 YK-----SRLLKGNLSHS 103
>Hs13787199 [L] KOG1133 Helicase of the DEAD superfamily
Length = 288
Score = 73.9 bits (180), Expect = 9e-13
Identities = 56/195 (28%), Positives = 87/195 (43%), Gaps = 40/195 (20%)
Query: 4 NFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKL 63
+F P+ PY IQ M +Y +L +GK +GIFESPTGTGK+LSLIC ++WLR+ + +K
Sbjct: 12 HFPFPFTPYSIQEDFMAELYRVLEAGK-IGIFESPTGTGKSLSLICGALSWLRDFEQKKR 70
Query: 64 NSKVD---------NDNLSDSTFSSSD-----------DEPEWVNQFYN--------DKI 95
+ +D +S SS EP WV QF D++
Sbjct: 71 EEEARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRL 130
Query: 96 MKEKSKSLQEYENYLEGLSMSNIKPVLRQLDIGDRKRK----------KTVPRHIEIE-I 144
E+++ Q E + +K ++L + +R+ +T P +E +
Sbjct: 131 KAEQARRKQREERLQQLQHRVQLKYAAKRLRQEEEERENLLRLSREMLETGPEAERLEQL 190
Query: 145 EDDETNFLPEPYEQD 159
E E + YE D
Sbjct: 191 ESGEEELVLAEYESD 205
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,076,943
Number of Sequences: 60738
Number of extensions: 2057544
Number of successful extensions: 6609
Number of sequences better than 1.0e-05: 28
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 6387
Number of HSP's gapped (non-prelim): 73
length of query: 807
length of database: 30,389,216
effective HSP length: 115
effective length of query: 692
effective length of database: 23,404,346
effective search space: 16195807432
effective search space used: 16195807432
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)