ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7274 good T KOG0787 Signal transduction mechanisms Dehydrogenase kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7274 2538891 2537356 -512
(512 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPAC644.11c [T] KOG0787 Dehydrogenase kinase 312 7e-85
At3g06483 [T] KOG0787 Dehydrogenase kinase 202 7e-52
Hs19923736 [T] KOG0787 Dehydrogenase kinase 192 1e-48
Hs4505689 [T] KOG0787 Dehydrogenase kinase 183 6e-46
Hs4885545 [T] KOG0787 Dehydrogenase kinase 181 2e-45
7303893 [T] KOG0787 Dehydrogenase kinase 181 3e-45
CE00397 [T] KOG0787 Dehydrogenase kinase 171 2e-42
Hs4505693 [T] KOG0787 Dehydrogenase kinase 167 5e-41
Hs11432626 [T] KOG0787 Dehydrogenase kinase 141 3e-33
Hs5031609 [T] KOG0787 Dehydrogenase kinase 139 1e-32
YIL042c [T] KOG0787 Dehydrogenase kinase 80 6e-15
>SPAC644.11c [T] KOG0787 Dehydrogenase kinase
Length = 425
Score = 312 bits (800), Expect = 7e-85
Identities = 195/512 (38%), Positives = 286/512 (55%), Gaps = 100/512 (19%)
Query: 8 SLLTKIWQYSETPQTAVSLRQMCQFGSHPTPGLMFKASCFLLNELPVRLAHRIKELESLP 67
+L K+ ++ PQT +SL+Q+ FG +PTPG +F+A FL +ELP+RLA RI++L++L
Sbjct: 7 TLQEKVNLLAQYPQTGLSLKQLVYFGKNPTPGTLFRAGLFLRDELPIRLARRIQDLQNLS 66
Query: 68 RGLNKVEEVITVRDWYTQSFQDLYNFSHDESQKHGAIFQSLFYGSNSANVDHLIRLLFTQ 127
L ++ + +V+ Y +S +++
Sbjct: 67 PMLRSMKRISSVKAAYGRSMEEII------------------------------------ 90
Query: 128 EEIKSMEQSKGSSNHLYC----KHKKFIDDGIVMKIPGPSSNHHSQHNKSGGKVPLPQKY 183
E+K +E K H K + + D ++ P +N H +K +Y
Sbjct: 91 -ELKGVELPKCLPKHARYHNAPKWRSSLMDSEILHNPS-LANTHLDSSKG--------RY 140
Query: 184 FSPLPSSTVSGWNKSQDFYQFWPADLLLFNRNFYNVLQNIKERHDATVITLAKGVLKWKK 243
F S +G + + WP LL FN NF +L I+ RHD + +A + ++++
Sbjct: 141 FETDFSDQDNGVDCN------WPESLLKFNSNFAYLLNTIRTRHDNVAVEIALDIQEYRR 194
Query: 244 THQQNVVDDSIQSFLDRFYLSRIGIRMLIGQQLALLESARQPAEGPFDEDDEDWVGIICT 303
+ N +D+SIQ FLDRFY+SRIGIRML+GQ +AL+ + E++VG+I T
Sbjct: 195 --KTNQIDNSIQIFLDRFYMSRIGIRMLLGQYIALVSEPPR----------ENYVGVIST 242
Query: 304 KTNITQLSKTAIDNARHICAEHYGLYEAPKVQLLTFPLDYRPSTEEKSGCPNESPDIEFM 363
+ NI Q+ + A +NA++IC YGL+EAP++Q++ P +E M
Sbjct: 243 RANIYQIIEGAAENAKYICRLAYGLFEAPEIQIIC------------------DPSLEMM 284
Query: 364 YVPGHLIHMLFETLKNALRATVEKTIEKNPSVDKYDLKFPDVKVIITEGTEDLTVKISDE 423
YV HL H +FE LKN+LRATVE VD D FP +KVI+ +G ED+T+KISDE
Sbjct: 285 YVESHLNHAVFEILKNSLRATVEFH-----GVDS-DF-FPPIKVIVAKGQEDITIKISDE 337
Query: 424 GGGIARSNLPLVWTYLYTTMPENEQIGLMDEE---MSQNFRIPMAGYGYGLALSRLYARY 480
GGGI+R N+PLVW+Y++TT L D+ +S N PMAG+G+GL L+RLY RY
Sbjct: 338 GGGISRRNIPLVWSYMFTTASPT----LTDDPHDIVSANSTTPMAGFGFGLPLARLYTRY 393
Query: 481 FGGDLKLMSMEGFGTDVYLHLNRLSTSSEPLQ 512
FGGDL+L+SMEG+GTDVY+HLNRL S+EPLQ
Sbjct: 394 FGGDLELISMEGYGTDVYIHLNRLCESAEPLQ 425
>At3g06483 [T] KOG0787 Dehydrogenase kinase
Length = 380
Score = 202 bits (515), Expect = 7e-52
Identities = 126/316 (39%), Positives = 179/316 (55%), Gaps = 62/316 (19%)
Query: 214 RNFYNVLQNIKERHDATVITLAKGVLKWKKTHQQNVVDDSIQSFLDRFYLSRIGIRMLIG 273
++F +++ +K RH+ V +A GV + KK +D+ I FLDRFYLSRIGIRMLIG
Sbjct: 108 KDFTQMIKAVKVRHNNVVPMMALGVNQLKKGMNSGNLDE-IHQFLDRFYLSRIGIRMLIG 166
Query: 274 QQLALLESARQPAEGPFDEDDEDWVGIICTKTNITQLSKTAIDNARHICAEHYGLYEAPK 333
Q + L + P VG I TK + ++++ A ++AR IC YG AP+
Sbjct: 167 QHVEL-HNPNPPLHT---------VGYIHTKMSPMEVARNASEDARSICFREYG--SAPE 214
Query: 334 VQLLTFPLDYRPSTEEKSGCPNESPDIEFMYVPGHLIHMLFETLKNALRATVEKTIEKNP 393
+ + P F YVP HL M++E +KN+LRA E+ ++
Sbjct: 215 INIYG------------------DPSFTFPYVPTHLHLMMYELVKNSLRAVQERFVDS-- 254
Query: 394 SVDKYDLKFPDVKVIITEGTEDLTVK--------------ISDEGGGIARSNLPLVWTYL 439
D P +++I+ +G ED+T+K +SDEGGGIARS LP ++TYL
Sbjct: 255 -----DRVAPPIRIIVADGIEDVTIKPFRSLLHRFDPIIVVSDEGGGIARSGLPRIFTYL 309
Query: 440 YTT----MPENEQIGLMDEEMSQNFRIPMAGYGYGLALSRLYARYFGGDLKLMSMEGFGT 495
Y+T + E+ +G+ D ++ MAGYGYGL +SRLYARYFGGDL+++SMEG+GT
Sbjct: 310 YSTARNPLEEDVDLGIADVPVT------MAGYGYGLPISRLYARYFGGDLQIISMEGYGT 363
Query: 496 DVYLHLNRLSTSSEPL 511
D YLHL+RL S EPL
Sbjct: 364 DAYLHLSRLGDSQEPL 379
Score = 80.1 bits (196), Expect = 7e-15
Identities = 44/98 (44%), Positives = 61/98 (61%), Gaps = 5/98 (5%)
Query: 1 MAVK-----FPSSLLTKIWQYSETPQTAVSLRQMCQFGSHPTPGLMFKASCFLLNELPVR 55
MAVK FP SL+ + ++ QT VSLR M +FGS PT + ++ FL ELP+R
Sbjct: 1 MAVKKACEMFPKSLIEDVHKWGCMKQTGVSLRYMMEFGSKPTERNLLISAQFLHKELPIR 60
Query: 56 LAHRIKELESLPRGLNKVEEVITVRDWYTQSFQDLYNF 93
+A R EL++LP GL+ V+ VRDWY +SF+D+ F
Sbjct: 61 VARRAIELQTLPYGLSDKPAVLKVRDWYLESFRDMRAF 98
>Hs19923736 [T] KOG0787 Dehydrogenase kinase
Length = 407
Score = 192 bits (488), Expect = 1e-48
Identities = 113/294 (38%), Positives = 166/294 (56%), Gaps = 39/294 (13%)
Query: 216 FYNVLQNIKERHDATVITLAKGVLKWKKTHQQNVVDD-SIQSFLDRFYLSRIGIRMLIGQ 274
F + L I+ RH+ V T+A+GVL++K T+ + V + +IQ FLDRFYLSRI IRMLI Q
Sbjct: 112 FTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQ 171
Query: 275 QLALLESARQPAEGPFDEDDEDWVGIICTKTNITQLSKTAIDNARHICAEHYGLYEAPKV 334
+ + + PA +G I N++++ K A D A+ +C ++Y +P +
Sbjct: 172 HTLIFDGSTNPAHPKH-------IGSIDPNCNVSEVVKDAYDMAKLLCDKYY--MASPDL 222
Query: 335 QLLTFPLDYRPSTEEKSGCPNESPDIEFMYVPGHLIHMLFETLKNALRATVEKTIEKNPS 394
++ ++ N I +YVP HL HMLFE KNA+RATVE
Sbjct: 223 EI------------QEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVES------- 263
Query: 395 VDKYDLKFPDVKVIITEGTEDLTVKISDEGGGIARSNLPLVWTYLYTTMPENEQIGLMDE 454
+ L P +KV++ G EDL++K+SD GGG+ + +++Y+Y+T P +
Sbjct: 264 -HESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQP------ 316
Query: 455 EMSQNFRIPMAGYGYGLALSRLYARYFGGDLKLMSMEGFGTDVYLHLNRLSTSS 508
P+AG+GYGL +SRLYA+YF GDL+L SMEGFGTD ++L LST S
Sbjct: 317 ---GTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDS 367
>Hs4505689 [T] KOG0787 Dehydrogenase kinase
Length = 436
Score = 183 bits (464), Expect = 6e-46
Identities = 104/295 (35%), Positives = 165/295 (55%), Gaps = 36/295 (12%)
Query: 215 NFYNVLQNIKERHDATVITLAKGVLKWKKTHQQN-VVDDSIQSFLDRFYLSRIGIRMLIG 273
+F + + I+ RH+ + T+A+GV+++K++ + V ++Q FLDRFY+SRI IRML+
Sbjct: 137 DFTDTVIRIRNRHNDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLN 196
Query: 274 QQLALLESARQPAEGPFDEDDEDWVGIICTKTNITQLSKTAIDNARHICAEHYGLYEAPK 333
Q L +G +G I N+ ++ K +NAR +C +Y +P+
Sbjct: 197 QHSLLFGG-----KGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYY--INSPE 249
Query: 334 VQLLTFPLDYRPSTEEKSGCPNESPDIEFMYVPGHLIHMLFETLKNALRATVEKTIEKNP 393
++L E+ + I+ +YVP HL HM+FE KNA+RAT+E +
Sbjct: 250 LEL------------EELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGV 297
Query: 394 SVDKYDLKFPDVKVIITEGTEDLTVKISDEGGGIARSNLPLVWTYLYTTMPENEQIGLMD 453
+P ++V +T G EDLTVK+SD GGG+ + ++ Y+Y+T P
Sbjct: 298 --------YPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPR-------- 341
Query: 454 EEMSQNFRIPMAGYGYGLALSRLYARYFGGDLKLMSMEGFGTDVYLHLNRLSTSS 508
+ + +P+AG+GYGL +SRLYA+YF GDLKL S+EG+GTD +++ LST S
Sbjct: 342 PRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDS 396
Score = 52.8 bits (125), Expect = 1e-06
Identities = 31/90 (34%), Positives = 47/90 (51%), Gaps = 2/90 (2%)
Query: 16 YSETPQTAVSLRQMCQFGSHPTPGLMFKASCFLLNELPVRLAHRIKELESLPRGLNKVEE 75
Y+ + +S++Q FGS + FL ELPVRLA+ +KE+ LP L +
Sbjct: 49 YARFSPSPLSMKQFLDFGS--VNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPS 106
Query: 76 VITVRDWYTQSFQDLYNFSHDESQKHGAIF 105
V V+ WY QS Q+L +F ++ AI+
Sbjct: 107 VQLVQSWYIQSLQELLDFKDKSAEDAKAIY 136
>Hs4885545 [T] KOG0787 Dehydrogenase kinase
Length = 406
Score = 181 bits (460), Expect = 2e-45
Identities = 111/295 (37%), Positives = 161/295 (53%), Gaps = 37/295 (12%)
Query: 215 NFYNVLQNIKERHDATVITLAKGVLKWK-KTHQQNVVDDSIQSFLDRFYLSRIGIRMLIG 273
NF VL ++ RH+ V T+A+GV+++K K + +IQ FLDRFY +RI RMLI
Sbjct: 107 NFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFGFDPFISTNIQYFLDRFYTNRISFRMLIN 166
Query: 274 QQLALLESARQPAEGPFDEDDEDWVGIICTKTNITQLSKTAIDNARHICAEHYGLYEAPK 333
Q L P +G I N+ + K A + A+ +C ++Y + AP+
Sbjct: 167 QHTLLFGGDTNPVHPKH-------IGSIDPTCNVADVVKDAYETAKMLCEQYYLV--APE 217
Query: 334 VQLLTFPLDYRPSTEEKSGCPNESPDIEFMYVPGHLIHMLFETLKNALRATVEKTIEKNP 393
+++ EE + + P I+ +YVP HL HMLFE KN++RATVE ++
Sbjct: 218 LEV-----------EEFNAKAPDKP-IQVVYVPSHLFHMLFELFKNSMRATVELYEDRKE 265
Query: 394 SVDKYDLKFPDVKVIITEGTEDLTVKISDEGGGIARSNLPLVWTYLYTTMPENEQIGLMD 453
+P VK ++T G EDL++KISD GGG+ + ++ Y+Y+T P
Sbjct: 266 G-------YPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAPR-------- 310
Query: 454 EEMSQNFRIPMAGYGYGLALSRLYARYFGGDLKLMSMEGFGTDVYLHLNRLSTSS 508
+ P+AG+GYGL +SRLYARYF GDLKL SMEG GTD ++L LS+ S
Sbjct: 311 PSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSES 365
>7303893 [T] KOG0787 Dehydrogenase kinase
Length = 413
Score = 181 bits (458), Expect = 3e-45
Identities = 123/339 (36%), Positives = 174/339 (51%), Gaps = 41/339 (12%)
Query: 179 LPQKYFSPLPSSTVSGW--NKSQDFYQFWPADLLLFN-RNFYNVLQNIKERHDATVITLA 235
LP S VS W +D + A+ N + F L I+ RH+ V T+A
Sbjct: 72 LPDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEPTHDNLQKFVADLDLIRNRHNDVVQTMA 131
Query: 236 KGVLKWKKTHQQNV---VDDSIQSFLDRFYLSRIGIRMLIGQQLALLESARQPAEGPFDE 292
+GV++ K+ V + SIQ FLDR Y+SRI IRMLI Q LL A G
Sbjct: 132 QGVIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQH-TLLFGGNPHAGGRH-- 188
Query: 293 DDEDWVGIICTKTNITQLSKTAIDNARHICAEHYGLYEAPKVQLLTFPLDYRPSTEEKSG 352
+G + +++ + + A +NAR +C ++Y A ++Q + S
Sbjct: 189 -----IGCLDPACDLSDVVRDAYENARFLCDQYYLTSPALEIQ-------------QHSS 230
Query: 353 CPNESPDIEFMYVPGHLIHMLFETLKNALRATVEKTIEKNPSVDKYDLKFPDVKVIITEG 412
P ++ I +YVP HL +MLFE KN++RA VE N P +KV I +G
Sbjct: 231 EPGDNLPIRTVYVPSHLYYMLFELFKNSMRAVVEHHGHDNNDT------LPPLKVAICKG 284
Query: 413 TEDLTVKISDEGGGIARSNLPLVWTYLYTTMPENEQIGLMDEEMSQNFRIPMAGYGYGLA 472
ED+ VKISD+GGGI RS ++ Y+Y+T P+ + L +P+AGYGYGL
Sbjct: 285 KEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQPSKSDL--------HTVPLAGYGYGLP 336
Query: 473 LSRLYARYFGGDLKLMSMEGFGTDVYLHLNRLSTSSEPL 511
+SRLYARYF GD+ L+S EGFGTD ++L LS + L
Sbjct: 337 ISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANEL 375
Score = 51.2 bits (121), Expect = 4e-06
Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 8/99 (8%)
Query: 7 SSLLTKIWQYSETPQTAVSLRQMCQFGSHPTPGLMFKASCFLLNELPVRLAHRIKELESL 66
+SL + YS + +S++Q FG + K+ FL ELPVRLA+ +KE+ L
Sbjct: 16 ASLAKMLDFYSGFNPSPLSIKQFMDFGQNACEK---KSYIFLRKELPVRLANIMKEIALL 72
Query: 67 PRGLNKVEEVITVRDWYTQSFQDLYNF-----SHDESQK 100
P L V V WY +SF+D+ + +HD QK
Sbjct: 73 PDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEPTHDNLQK 111
>CE00397 [T] KOG0787 Dehydrogenase kinase
Length = 401
Score = 171 bits (433), Expect = 2e-42
Identities = 118/333 (35%), Positives = 170/333 (50%), Gaps = 55/333 (16%)
Query: 179 LPQKYFSPLPSSTVSGWNKSQDFYQFWPADLLLFNRN---------FYNVLQNIKERHDA 229
LP K S VS W ++ F DLLLF + F + L + +RH
Sbjct: 69 LPPKLLQMPSSKMVSNWY-AESF-----EDLLLFEASDSSPEQVARFNDQLTVVLKRHAH 122
Query: 230 TVITLAKGVLKWKKTHQQNVVDDS-IQSFLDRFYLSRIGIRMLIGQQLALLESARQPAEG 288
V T+A+G+++ +++ ++ + IQ FLDRFY++RI IRML Q L + G
Sbjct: 123 VVETMAEGLIELRESDGVDIASEKGIQYFLDRFYINRISIRMLQNQHLVVF--------G 174
Query: 289 PFDEDDEDWVGIICTKTNITQLSKTAIDNARHICAEHYGLYEAPKVQLLTFPLDYRPSTE 348
+ VG I ++ + A +NAR +C +Y +P ++L
Sbjct: 175 NVLPESPRHVGCIDPACDVESVVYDAFENARFLCDRYY--LTSPSMKL------------ 220
Query: 349 EKSGCPNESPDIEFMYVPGHLIHMLFETLKNALRATVEKTIEKNPSVDKYDLKFPDVKVI 408
E + I + VP HL HM+FE KNA+RATVE D PD+KV
Sbjct: 221 EMHNAVEKGKPISIVAVPSHLYHMMFELFKNAMRATVE--------YHGVDDDLPDIKVY 272
Query: 409 ITEGTEDLTVKISDEGGGIARSNLPLVWTYLYTTMPENEQIGLMDEEMSQNFRIPMAGYG 468
+ +G EDL++KI D GGG++R+ L ++ Y+Y+T P + G + P+AGYG
Sbjct: 273 VVKGQEDLSIKICDRGGGVSRTILERLYNYMYSTAPPPPRDGT---------QAPLAGYG 323
Query: 469 YGLALSRLYARYFGGDLKLMSMEGFGTDVYLHL 501
YGL LSRLYARYF GDL L+SMEG GTD ++L
Sbjct: 324 YGLPLSRLYARYFLGDLFLVSMEGHGTDACIYL 356
Score = 50.4 bits (119), Expect = 6e-06
Identities = 32/94 (34%), Positives = 50/94 (53%), Gaps = 3/94 (3%)
Query: 5 FPSSLLTKIWQYSETPQTAVSLRQMCQFGSHPTPGLMFKASCFLLNELPVRLAHRIKELE 64
F SL K+ YS+ ++++++Q FG T + FL NEL VRLA+ ++E
Sbjct: 11 FVGSLAKKLDYYSQFQPSSLTIQQYLDFGRIGTSANSYT---FLKNELLVRLANIMQEFT 67
Query: 65 SLPRGLNKVEEVITVRDWYTQSFQDLYNFSHDES 98
LP L ++ V +WY +SF+DL F +S
Sbjct: 68 LLPPKLLQMPSSKMVSNWYAESFEDLLLFEASDS 101
>Hs4505693 [T] KOG0787 Dehydrogenase kinase
Length = 411
Score = 167 bits (422), Expect = 5e-41
Identities = 104/310 (33%), Positives = 170/310 (54%), Gaps = 40/310 (12%)
Query: 200 DFYQFWPADLLLFNRNFYNVLQNIKERHDATVITLAKGVLKWKKTHQQN-VVDDSIQSFL 258
+F++ P D + +F + L ++ RH V T+A+G++++K + V + ++Q FL
Sbjct: 101 EFHEKSPDDQKALS-DFVDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFL 159
Query: 259 DRFYLSRIGIRMLIGQQLALLESARQPAEGPFDEDDEDWVGIICTKTNITQLSKTAIDNA 318
DRFY++RI RML+ Q + + ++ + +G I ++ + + A + +
Sbjct: 160 DRFYMNRISTRMLMNQHILIFSDSQT--------GNPSHIGSIDPNCDVVAVVQDAFECS 211
Query: 319 RHICAEHYGLYEAPKVQLLTFPLDYRPSTEEKSGCPNESPDIEFMYVPGHLIHMLFETLK 378
R +C ++Y +P+++L T+ P++ I +YVP HL HMLFE K
Sbjct: 212 RMLCDQYY--LSSPELKL----------TQVNGKFPDQP--IHIVYVPSHLHHMLFELFK 257
Query: 379 NALRATVEKTIEKNPSVDKYDLKFPDVKVIITEGTEDLTVKISDEGGGIARSNLPLVWTY 438
NA+RATVE E PS+ ++VI+ G EDLT+KISD GGG+ + +++Y
Sbjct: 258 NAMRATVEHQ-ENQPSLTP-------IEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSY 309
Query: 439 LYTTMPENEQIGLMDEEMSQNFRIPMAGYGYGLALSRLYARYFGGDLKLMSMEGFGTDVY 498
Y+T P M + P+AG+GYGL +SRLYA+YF GDL L S+ G+GTD
Sbjct: 310 TYSTAPT--------PVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAI 361
Query: 499 LHLNRLSTSS 508
++L LS+ S
Sbjct: 362 IYLKALSSES 371
Score = 52.8 bits (125), Expect = 1e-06
Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 6/84 (7%)
Query: 15 QYSETPQTAVSLRQMCQFGSHPTPGLMFKASCFLLNELPVRLAHRIKELESLPRGLNKVE 74
+YS +P +S++Q+ FGS + FL ELPVRLA+ +KE++ LP L
Sbjct: 29 RYSPSP---LSMKQLLDFGSENA--CERTSFAFLRQELPVRLANILKEIDILPTQLVNTS 83
Query: 75 EVITVRDWYTQSFQDLYNFSHDES 98
V V+ WY QS DL F H++S
Sbjct: 84 SVQLVKSWYIQSLMDLVEF-HEKS 106
>Hs11432626 [T] KOG0787 Dehydrogenase kinase
Length = 412
Score = 141 bits (355), Expect = 3e-33
Identities = 100/302 (33%), Positives = 150/302 (49%), Gaps = 52/302 (17%)
Query: 216 FYNVLQNIKERHDATVITLAKGVLKWKKTHQQNVVDDS-IQSFLDRFYLSRIGIRMLIGQ 274
+ +++ + + H V LA+G+ + +K ++ D+ ++ FLD+ SR+GIRML
Sbjct: 151 YCQLVRQLLDDHKDVVTLLAEGLRESRK----HIEDEKLVRYFLDKTLTSRLGIRMLATH 206
Query: 275 QLALLESARQPAEGPFDEDDEDWVGIICTKTNITQLSKTAIDNARHICAEHYGLYEAPKV 334
LAL ED D+VGIICT+ + ++ + +D AR +C YG AP+V
Sbjct: 207 HLAL------------HEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYG--NAPRV 252
Query: 335 QLLTFPLDYRPSTEEKSGCPNESPDIEFMYVPGHLIHMLFETLKNALRATVEKTIEKNPS 394
++ N F ++P L ++L E LKNA+RAT+E ++ +
Sbjct: 253 RI------------------NGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYN 294
Query: 395 VDKYDLKFPDVKVIITEGTEDLTVKISDEGGGIARSNLPLVWTYLYTTMPENEQ------ 448
V PDV + I DL ++ISD GGGIA +L V Y +TT + Q
Sbjct: 295 V-------PDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISP 347
Query: 449 -IGLMDEEMSQNFRIPMAGYGYGLALSRLYARYFGGDLKLMSMEGFGTDVYLHLNRLSTS 507
G +D PM G+G+GL SR YA Y GG L+L S++G GTDVYL L +
Sbjct: 348 LFGHLDMHSGAQSG-PMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGR 406
Query: 508 SE 509
E
Sbjct: 407 EE 408
>Hs5031609 [T] KOG0787 Dehydrogenase kinase
Length = 412
Score = 139 bits (350), Expect = 1e-32
Identities = 99/302 (32%), Positives = 149/302 (48%), Gaps = 52/302 (17%)
Query: 216 FYNVLQNIKERHDATVITLAKGVLKWKKTHQQNVVDDS-IQSFLDRFYLSRIGIRMLIGQ 274
+ +++ + + H V LA+G+ + +K ++ D+ ++ FLD+ SR+GIRML
Sbjct: 151 YCQLVRQLLDDHKDVVTLLAEGLRESRK----HIEDEKLVRYFLDKTLTSRLGIRMLATH 206
Query: 275 QLALLESARQPAEGPFDEDDEDWVGIICTKTNITQLSKTAIDNARHICAEHYGLYEAPKV 334
LAL ED D+ GIICT+ + ++ + +D AR +C YG AP+V
Sbjct: 207 HLAL------------HEDKPDFFGIICTRLSPKKIIEKWVDFARRLCEHKYG--NAPRV 252
Query: 335 QLLTFPLDYRPSTEEKSGCPNESPDIEFMYVPGHLIHMLFETLKNALRATVEKTIEKNPS 394
++ N F ++P L ++L E LKNA+RAT+E ++ +
Sbjct: 253 RI------------------NGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYN 294
Query: 395 VDKYDLKFPDVKVIITEGTEDLTVKISDEGGGIARSNLPLVWTYLYTTMPENEQ------ 448
V PDV + I DL ++ISD GGGIA +L V Y +TT + Q
Sbjct: 295 V-------PDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISP 347
Query: 449 -IGLMDEEMSQNFRIPMAGYGYGLALSRLYARYFGGDLKLMSMEGFGTDVYLHLNRLSTS 507
G +D PM G+G+GL SR YA Y GG L+L S++G GTDVYL L +
Sbjct: 348 LFGHLDMHSGAQSG-PMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGR 406
Query: 508 SE 509
E
Sbjct: 407 EE 408
>YIL042c [T] KOG0787 Dehydrogenase kinase
Length = 394
Score = 80.5 bits (197), Expect = 6e-15
Identities = 71/279 (25%), Positives = 123/279 (43%), Gaps = 48/279 (17%)
Query: 227 HDATVITLAKGVLKWKKTHQQNVVDDSIQSFLDRFYLSRIGIRMLIGQQLALLESARQPA 286
H+ ++ LAKG+ + + + + I FL+ RI +++L+ L+L+ +
Sbjct: 148 HEDAIVVLAKGLQEIQSCYPKF----QISQFLNFHLKERITMKLLVTHYLSLMAQNK--- 200
Query: 287 EGPFDEDDEDWVGIICTKTNITQLSKTAIDNARHICAEHYGLYEAPKVQLLTFPLDYRPS 346
+ ++ +GI+ I QL K D IC + P +L P
Sbjct: 201 ----GDTNKRMIGILHRDLPIAQLIKHVSDYVNDICFVKFNTQRTP---VLIHP------ 247
Query: 347 TEEKSGCPNESPDIEFMYVPGHLIHMLFETLKNALRATVEKTIEKNPSVDKYDLKFPDVK 406
S DI F +P L +++ E KNA A + E P + +L PD
Sbjct: 248 ---------PSQDITFTCIPPILEYIMTEVFKNAFEAQIALGKEHMPI--EINLLKPD-- 294
Query: 407 VIITEGTEDLTVKISDEGGGIARSNLPLVWTYLYTT----MPENEQIGLMDEEMSQNFRI 462
++L ++I D GGGI L++ Y Y+T ++E L E+++
Sbjct: 295 ------DDELYLRIRDHGGGITPEVEALMFNYSYSTHTQQSADSESTDLPGEQINN---- 344
Query: 463 PMAGYGYGLALSRLYARYFGGDLKLMSMEGFGTDVYLHL 501
++G G+GL + + Y FGG + + S+ G+GTDVY+ L
Sbjct: 345 -VSGMGFGLPMCKTYLELFGGKIDVQSLLGWGTDVYIKL 382
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,552,292
Number of Sequences: 60738
Number of extensions: 1493705
Number of successful extensions: 3565
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3500
Number of HSP's gapped (non-prelim): 21
length of query: 512
length of database: 30,389,216
effective HSP length: 111
effective length of query: 401
effective length of database: 23,647,298
effective search space: 9482566498
effective search space used: 9482566498
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)