ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7334 check: MH T KOG0703 Signal transduction mechanisms Predicted GTPase-activating protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7334 2555410 2554574 -279
(279 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL044c [T] KOG0703 Predicted GTPase-activating protein 159 5e-39
SPAC824.09c [T] KOG0703 Predicted GTPase-activating protein 141 1e-33
7303978 [T] KOG0703 Predicted GTPase-activating protein 104 1e-22
HsM11345478 [T] KOG0703 Predicted GTPase-activating protein 103 4e-22
Hs21264558 [T] KOG0703 Predicted GTPase-activating protein 103 4e-22
CE16562 [T] KOG0703 Predicted GTPase-activating protein 103 4e-22
Hs17441611 [T] KOG0703 Predicted GTPase-activating protein 100 2e-21
At5g54310 [T] KOG0703 Predicted GTPase-activating protein 99 5e-21
At4g05330_1 [T] KOG0703 Predicted GTPase-activating protein 97 3e-20
At3g07940_1 [T] KOG0703 Predicted GTPase-activating protein 85 1e-16
At3g17660 [T] KOG0703 Predicted GTPase-activating protein 84 2e-16
Hs22044335 [T] KOG0521 Putative GTPase activating proteins (GAPs) 83 5e-16
Hs16945966 [T] KOG0521 Putative GTPase activating proteins (GAPs) 83 5e-16
SPBC21D10.05c_1 [T] KOG0703 Predicted GTPase-activating protein 81 2e-15
7298111 [T] KOG0705 GTPase-activating protein Centaurin gamma (c... 80 4e-15
Hs7662484 [T] KOG0705 GTPase-activating protein Centaurin gamma ... 77 2e-14
Hs17977656 [T] KOG0521 Putative GTPase activating proteins (GAPs) 76 5e-14
7300962 [T] KOG0521 Putative GTPase activating proteins (GAPs) 75 8e-14
Hs6806913 [T] KOG0703 Predicted GTPase-activating protein 75 1e-13
Hs20547911 [T] KOG0705 GTPase-activating protein Centaurin gamma... 74 2e-13
Hs16799069 [T] KOG0705 GTPase-activating protein Centaurin gamma... 74 3e-13
At4g21160_1 [T] KOG0703 Predicted GTPase-activating protein 74 3e-13
CE28116 [T] KOG0705 GTPase-activating protein Centaurin gamma (c... 72 9e-13
CE20232 [T] KOG0705 GTPase-activating protein Centaurin gamma (c... 72 9e-13
CE19135 [T] KOG0705 GTPase-activating protein Centaurin gamma (c... 72 9e-13
Hs8923763 [T] KOG0703 Predicted GTPase-activating protein 71 1e-12
At2g37550 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator 71 1e-12
Hs20547087 [T] KOG0705 GTPase-activating protein Centaurin gamma... 71 2e-12
HsM18034686 [T] KOG0705 GTPase-activating protein Centaurin gamm... 70 3e-12
Hs7661962 [T] KOG0705 GTPase-activating protein Centaurin gamma ... 70 3e-12
SPCC622.14 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator 69 6e-12
Hs22051953 [T] KOG0705 GTPase-activating protein Centaurin gamma... 69 6e-12
Hs19263343 [T] KOG0705 GTPase-activating protein Centaurin gamma... 69 6e-12
CE11618 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator 69 6e-12
At3g53710 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator 69 6e-12
At5g61980 [T] KOG0521 Putative GTPase activating proteins (GAPs) 69 7e-12
At1g60860 [T] KOG0521 Putative GTPase activating proteins (GAPs) 69 7e-12
7294580 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator 69 7e-12
Hs7661880 [T] KOG0521 Putative GTPase activating proteins (GAPs) 69 1e-11
Hs22051029 [T] KOG0705 GTPase-activating protein Centaurin gamma... 69 1e-11
Hs22052038 [T] KOG0705 GTPase-activating protein Centaurin gamma... 68 2e-11
Hs20543681 [T] KOG0705 GTPase-activating protein Centaurin gamma... 68 2e-11
Hs8922652 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator 67 2e-11
At2g35210 [T] KOG0706 Predicted GTPase-activating protein 67 2e-11
At1g10870 [T] KOG0521 Putative GTPase activating proteins (GAPs) 67 2e-11
Hs22053338 [T] KOG0705 GTPase-activating protein Centaurin gamma... 67 3e-11
At5g46750 [T] KOG0706 Predicted GTPase-activating protein 67 3e-11
At4g17890_1 [T] KOG0706 Predicted GTPase-activating protein 66 5e-11
At5g13300 [T] KOG0521 Putative GTPase activating proteins (GAPs) 65 1e-10
YDR524c [T] KOG0521 Putative GTPase activating proteins (GAPs) 64 2e-10
Hs21264337_1 [TZ] KOG1117 Rho- and Arf-GTPase activating protein... 64 2e-10
7296565 [T] KOG0706 Predicted GTPase-activating protein 64 3e-10
At2g14490 [T] KOG0703 Predicted GTPase-activating protein 63 4e-10
7304095 [T] KOG0521 Putative GTPase activating proteins (GAPs) 63 4e-10
Hs22065234 [T] KOG0706 Predicted GTPase-activating protein 63 5e-10
SPAC22E12.17c [T] KOG0706 Predicted GTPase-activating protein 62 7e-10
Hs22047742 [T] KOG0521 Putative GTPase activating proteins (GAPs) 62 7e-10
ECU11g0550 [T] KOG0706 Predicted GTPase-activating protein 62 7e-10
YDL226c [TUZ] KOG0704 ADP-ribosylation factor GTPase activator 62 9e-10
Hs14150223 [T] KOG0706 Predicted GTPase-activating protein 62 9e-10
Hs20070255 [T] KOG0706 Predicted GTPase-activating protein 60 3e-09
SPBC17G9.08c [T] KOG0521 Putative GTPase activating proteins (GAPs) 60 4e-09
ECU08g1690 [T] KOG0706 Predicted GTPase-activating protein 59 8e-09
YER122c [T] KOG0706 Predicted GTPase-activating protein 59 1e-08
CE28110 [T] KOG0521 Putative GTPase activating proteins (GAPs) 59 1e-08
CE25223 [T] KOG0521 Putative GTPase activating proteins (GAPs) 59 1e-08
CE01896 [T] KOG0706 Predicted GTPase-activating protein 59 1e-08
SPAC26A3.10 [T] KOG0521 Putative GTPase activating proteins (GAPs) 58 1e-08
HsM16975482 [TZ] KOG1117 Rho- and Arf-GTPase activating protein ... 58 1e-08
Hs21264597 [TZ] KOG1117 Rho- and Arf-GTPase activating protein A... 58 1e-08
Hs21264592 [TZ] KOG1117 Rho- and Arf-GTPase activating protein A... 58 1e-08
Hs16975484 [TZ] KOG1117 Rho- and Arf-GTPase activating protein A... 58 1e-08
YGL181w_1 [T] KOG0703 Predicted GTPase-activating protein 58 2e-08
YNL204c [TUZ] KOG0704 ADP-ribosylation factor GTPase activator 57 2e-08
Hs4502249 [T] KOG0521 Putative GTPase activating proteins (GAPs) 56 5e-08
Hs19923540 [T] KOG0521 Putative GTPase activating proteins (GAPs) 56 6e-08
Hs4758562 [T] KOG0702 Predicted GTPase-activating protein 55 1e-07
Hs7661712 [T] KOG0818 GTPase-activating proteins of the GIT family 54 2e-07
HsM7661944 [T] KOG0818 GTPase-activating proteins of the GIT family 52 1e-06
Hs21237794 [T] KOG0818 GTPase-activating proteins of the GIT family 52 1e-06
Hs21237786 [T] KOG0818 GTPase-activating proteins of the GIT family 52 1e-06
Hs17149832 [T] KOG0818 GTPase-activating proteins of the GIT family 52 1e-06
Hs17149830 [T] KOG0818 GTPase-activating proteins of the GIT family 52 1e-06
7303716 [T] KOG0818 GTPase-activating proteins of the GIT family 52 1e-06
At1g08680 [T] KOG0702 Predicted GTPase-activating protein 50 4e-06
>YIL044c [T] KOG0703 Predicted GTPase-activating protein
Length = 298
Score = 159 bits (401), Expect = 5e-39
Identities = 94/235 (40%), Positives = 118/235 (50%), Gaps = 27/235 (11%)
Query: 2 TSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVK 61
TSV VKK L+ LLRDP N+ C DCK HPRWASWSLGVF+CIKCAG HRS+GTHISKVK
Sbjct: 3 TSVPVKKALSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVK 62
Query: 62 SVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLGG---GTYVPDQSKIGQFIRTKYELKKW 118
SVDLDTW EEHL +++F L + D S + FI+ KYE KKW
Sbjct: 63 SVDLDTWKEEHLVKLIQFKNNLRANSYYEATLADELKQRKITDTSSLQNFIKNKYEYKKW 122
Query: 119 VGD-----------DPIVDVKSSKHTAEAKD-RVAQKAAAVRNXXX-------XXXXXXX 159
+GD +P++ S+ H+ A + R+ Q + +++
Sbjct: 123 IGDLSSIEGLNDSTEPVLHKPSANHSLPASNARLDQSSNSLQKTQTQPPSHLLSTSRSNT 182
Query: 160 XXXXXXXXXXXXTDKNVPQISSEKP-----SATNTNVYRPPDRPDLKKSILSLYA 209
T N SS + T V R DLKKSILSLY+
Sbjct: 183 SLLNLQVSSLSKTTSNTSVTSSATSIGAANTKTGNRVGEFGQRNDLKKSILSLYS 237
>SPAC824.09c [T] KOG0703 Predicted GTPase-activating protein
Length = 320
Score = 141 bits (355), Expect = 1e-33
Identities = 88/267 (32%), Positives = 122/267 (44%), Gaps = 22/267 (8%)
Query: 9 VLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTW 68
VL +LLR+P N C DCK PRWASW+LGVF+CI+C+G HRS+G H+S+VKSVDLD+W
Sbjct: 15 VLKSLLREPYNKVCADCKRNEQPRWASWNLGVFICIRCSGVHRSLGVHVSRVKSVDLDSW 74
Query: 69 TEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQFIRTKYELKKWVGDDPIVDVK 128
T+E E + +G GG +VP SKI FI+TKYE KKWV I +
Sbjct: 75 TDEQTENMTRWGNERANLYWEAKLAGG--HVPSDSKIATFIKTKYEFKKWVLYPEIPSPE 132
Query: 129 SSKHTAEAKDRVAQKAAAVRNXXXXXXXXXXXXXXXXXXXXXXTDKN--VPQISSEKPSA 186
+ K + A+ N T K + +S S+
Sbjct: 133 TLKPEQNTRPVSEVNASLDLNTASRSSSAHSVKSTSSATVTNVTSKKEAISATTSLAQSS 192
Query: 187 TN--------TNVYRPPDRP-DLKKSILSLYANRKXXXXXXXXXXXXXXXXXXXXKNMST 237
N + V+ P R DLK SILSLYA+ + + ST
Sbjct: 193 PNLASLSKQPSTVHAPSTRQRDLKSSILSLYASPRPQVSSSSITTNATYQNLPSPVSTST 252
Query: 238 SNS---------LSSGGKLTSNPWAVP 255
++S ++G ++ W +P
Sbjct: 253 TSSQPYGAFHQPATTGSSFVADKWKMP 279
>7303978 [T] KOG0703 Predicted GTPase-activating protein
Length = 518
Score = 104 bits (260), Expect = 1e-22
Identities = 50/111 (45%), Positives = 69/111 (62%), Gaps = 1/111 (0%)
Query: 9 VLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTW 68
+LT +LRD +N C DC A PRWASW+LG+F+CI+CAG HR++G HIS+VKSV+LDTW
Sbjct: 20 LLTQMLRDEDNKYCVDCD-AKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDTW 78
Query: 69 TEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQFIRTKYELKKWV 119
T E + ++ + G G + + FIR KYE KK++
Sbjct: 79 TPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTALENFIRAKYEHKKYL 129
>HsM11345478 [T] KOG0703 Predicted GTPase-activating protein
Length = 437
Score = 103 bits (256), Expect = 4e-22
Identities = 61/198 (30%), Positives = 90/198 (44%), Gaps = 7/198 (3%)
Query: 9 VLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTW 68
+L+ LLR+ +N C DC+ A PRWASW++GVF+CI+CAG HR++G HIS+VKSV+LD W
Sbjct: 20 ILSKLLREEDNKYCADCE-AKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQW 78
Query: 69 TEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQFIRTKYELKKWVGDDPIV--- 125
T E ++ + + G + FIR KYE KK+ + I
Sbjct: 79 TAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYDKNAIAITN 138
Query: 126 DVKSSKHTAEAKDRVAQKAAAVRNXXXXXXXXXXXXXXXXXXXXXXTDKNVPQISSEKPS 185
K K + +++ +K A + V + + P+
Sbjct: 139 KEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPA 198
Query: 186 ---ATNTNVYRPPDRPDL 200
TN N PP DL
Sbjct: 199 VAPVTNGNTTVPPLNDDL 216
>Hs21264558 [T] KOG0703 Predicted GTPase-activating protein
Length = 440
Score = 103 bits (256), Expect = 4e-22
Identities = 61/198 (30%), Positives = 90/198 (44%), Gaps = 7/198 (3%)
Query: 9 VLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTW 68
+L+ LLR+ +N C DC+ A PRWASW++GVF+CI+CAG HR++G HIS+VKSV+LD W
Sbjct: 20 ILSKLLREEDNKYCADCE-AKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQW 78
Query: 69 TEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQFIRTKYELKKWVGDDPIV--- 125
T E ++ + + G + FIR KYE KK+ + I
Sbjct: 79 TAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYDKNAIAITN 138
Query: 126 DVKSSKHTAEAKDRVAQKAAAVRNXXXXXXXXXXXXXXXXXXXXXXTDKNVPQISSEKPS 185
K K + +++ +K A + V + + P+
Sbjct: 139 KEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPA 198
Query: 186 ---ATNTNVYRPPDRPDL 200
TN N PP DL
Sbjct: 199 VAPVTNGNTTVPPLNDDL 216
>CE16562 [T] KOG0703 Predicted GTPase-activating protein
Length = 495
Score = 103 bits (256), Expect = 4e-22
Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 5/135 (3%)
Query: 10 LTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWT 69
L +L++ EN C DC+ T PRWA+W+LGVF+CI+CAG HR++G HISKV+SV+LD+WT
Sbjct: 20 LLDMLKEEENKYCADCQAKT-PRWAAWNLGVFICIRCAGIHRNLGVHISKVRSVNLDSWT 78
Query: 70 EEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQFIRTKYELKKWVGDD---PIVD 126
E ++ + G + ++ QFIR+KYE K+++ D P VD
Sbjct: 79 PEQVQTMRVMGNEKARQVYEHDLPAQFRRPTNDQQMEQFIRSKYEQKRYILRDFVYPRVD 138
Query: 127 VKS-SKHTAEAKDRV 140
K ++A+ +V
Sbjct: 139 ASQLPKSLSQAQKKV 153
>Hs17441611 [T] KOG0703 Predicted GTPase-activating protein
Length = 429
Score = 100 bits (249), Expect = 2e-21
Identities = 53/136 (38%), Positives = 79/136 (57%), Gaps = 17/136 (12%)
Query: 9 VLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTW 68
VL LL + +N C DC+ + PRWASW++GVF+CI+CAG HR++G HIS+VKSV+LD W
Sbjct: 15 VLANLLLEEDNKFCADCQ-SKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQW 73
Query: 69 TEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQ-------FIRTKYELKKWVGD 121
T+E ++ + E G Y+P+ + Q FIR KYE KK++
Sbjct: 74 TQEQIQCMQEMGNGKANRLYE-------AYLPETFRRPQIDPAVEGFIRDKYEKKKYM-- 124
Query: 122 DPIVDVKSSKHTAEAK 137
D +D+ + + + K
Sbjct: 125 DRSLDINAFRKEKDDK 140
>At5g54310 [T] KOG0703 Predicted GTPase-activating protein
Length = 483
Score = 99.4 bits (246), Expect = 5e-21
Identities = 49/115 (42%), Positives = 66/115 (56%), Gaps = 9/115 (7%)
Query: 7 KKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
+K+L LL+ PEN C DCK PRWAS +LG+F+C++C+G HRS+G HISKV+S LD
Sbjct: 16 RKILEGLLKHPENRECADCKTKG-PRWASVNLGIFICMQCSGIHRSLGVHISKVRSATLD 74
Query: 67 TWTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKIG--QFIRTKYELKKWV 119
TW E + + G P+ ++G FIR KYE K+WV
Sbjct: 75 TWLPEQVAFIQSMGNDKANSYWE------AELPPNYDRVGIENFIRAKYEEKRWV 123
>At4g05330_1 [T] KOG0703 Predicted GTPase-activating protein
Length = 169
Score = 96.7 bits (239), Expect = 3e-20
Identities = 50/134 (37%), Positives = 79/134 (58%), Gaps = 7/134 (5%)
Query: 7 KKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
K+ + LL P+N C DC A+ P+WAS ++GVF+C+KC G HRS+GTHISKV SV LD
Sbjct: 15 KRRIRDLLNQPDNRVCADCG-ASDPKWASANIGVFICLKCCGVHRSLGTHISKVLSVTLD 73
Query: 67 TWTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVP----DQSKIGQFIRTKYELKKWVGDD 122
W++E +++++E G L P + + +FIR KYEL++++
Sbjct: 74 EWSDEEVDSMIEIGGNASANSIYEAFLPDTCSKPGPDVNHDQRMRFIRAKYELQEFL--K 131
Query: 123 PIVDVKSSKHTAEA 136
P + + S K + ++
Sbjct: 132 PSLRITSGKGSTKS 145
>At3g07940_1 [T] KOG0703 Predicted GTPase-activating protein
Length = 208
Score = 85.1 bits (209), Expect = 1e-16
Identities = 38/79 (48%), Positives = 54/79 (68%), Gaps = 1/79 (1%)
Query: 2 TSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVK 61
+S + + L LL+ P N C DC + P+W S SLGVF+CIKC+G HRS+G HISKV
Sbjct: 30 SSSDPRDRLEKLLKQPGNKYCADCG-SPEPKWVSLSLGVFICIKCSGVHRSLGVHISKVL 88
Query: 62 SVDLDTWTEEHLEAVLEFG 80
SV LD WT++ ++ ++ +G
Sbjct: 89 SVKLDEWTDDQVDMLVGYG 107
>At3g17660 [T] KOG0703 Predicted GTPase-activating protein
Length = 117
Score = 84.0 bits (206), Expect = 2e-16
Identities = 33/66 (50%), Positives = 50/66 (75%), Gaps = 1/66 (1%)
Query: 8 KVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDT 67
K+L LL+ P+N C DC+ + PRWAS +LG+F+C++C+G HRS+G HIS+V+S+ LDT
Sbjct: 17 KILEALLKHPDNRECADCR-SKAPRWASVNLGIFICMQCSGIHRSLGVHISQVRSITLDT 75
Query: 68 WTEEHL 73
W + +
Sbjct: 76 WLPDQV 81
>Hs22044335 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 834
Score = 82.8 bits (203), Expect = 5e-16
Identities = 47/125 (37%), Positives = 68/125 (53%), Gaps = 5/125 (4%)
Query: 4 VEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSV 63
V+ + VL + N++CGDC PRWAS +LGV +CI+C+G HRS+G H SKV+S+
Sbjct: 400 VKGESVLQRVQSVAGNSQCGDCG-QPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSL 458
Query: 64 DLDTWTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQ----FIRTKYELKKWV 119
LD+W E L+ + E G G G+ P S Q +I+ KY KK++
Sbjct: 459 TLDSWEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFL 518
Query: 120 GDDPI 124
P+
Sbjct: 519 RKAPM 523
>Hs16945966 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 759
Score = 82.8 bits (203), Expect = 5e-16
Identities = 47/125 (37%), Positives = 68/125 (53%), Gaps = 5/125 (4%)
Query: 4 VEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSV 63
V+ + VL + N++CGDC PRWAS +LGV +CI+C+G HRS+G H SKV+S+
Sbjct: 358 VKGESVLQRVQSVAGNSQCGDCG-QPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSL 416
Query: 64 DLDTWTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQ----FIRTKYELKKWV 119
LD+W E L+ + E G G G+ P S Q +I+ KY KK++
Sbjct: 417 TLDSWEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFL 476
Query: 120 GDDPI 124
P+
Sbjct: 477 RKAPM 481
>SPBC21D10.05c_1 [T] KOG0703 Predicted GTPase-activating protein
Length = 156
Score = 80.9 bits (198), Expect = 2e-15
Identities = 38/107 (35%), Positives = 61/107 (56%), Gaps = 4/107 (3%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLE 78
NN C DC +WASW+LG+F+C++CA HR +GTH+SKVKS+ LD W+ + +E +
Sbjct: 20 NNLCADCSTRG-VQWASWNLGIFLCLRCATIHRKLGTHVSKVKSISLDEWSNDQIEKMKH 78
Query: 79 FGXXXXXXXXXXXXLG---GGTYVPDQSKIGQFIRTKYELKKWVGDD 122
+G L + D+ + ++IR KYE K ++ ++
Sbjct: 79 WGNINANRYWNPNPLSHPLPTNALSDEHVMEKYIRDKYERKLFLDEN 125
>7298111 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 895
Score = 79.7 bits (195), Expect = 4e-15
Identities = 43/120 (35%), Positives = 65/120 (53%), Gaps = 3/120 (2%)
Query: 2 TSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVK 61
TS ++ +L R P N C DC A +P WAS +LGV +CI+C+G HR++G+HISKV+
Sbjct: 597 TSTDLAAMLAIRQRVPGNGFCVDCG-APNPEWASLNLGVLMCIECSGVHRNLGSHISKVR 655
Query: 62 SVDLDTWTEEHLEAVLEFGXXXXXX--XXXXXXLGGGTYVPDQSKIGQFIRTKYELKKWV 119
S+ LD W HL +L G T + +++R+KYE K+++
Sbjct: 656 SLGLDDWPSPHLSVMLAIGNSLANSVWESNTRQRVKPTSQASREDKERWVRSKYEAKEFL 715
>Hs7662484 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 804
Score = 77.4 bits (189), Expect = 2e-14
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 3/138 (2%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
+TS L ++ N+ C DC+ +P WAS +LG +CI+C+G HR++GTH+S+V
Sbjct: 550 LTSQSEAMALQSIRNMRGNSHCVDCETQ-NPNWASLNLGALMCIECSGIHRNLGTHLSRV 608
Query: 61 KSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSK--IGQFIRTKYELKKW 118
+S+DLD W E ++ + G G D ++ ++IR KYE K +
Sbjct: 609 RSLDLDDWPIELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLF 668
Query: 119 VGDDPIVDVKSSKHTAEA 136
+ P ++ +H A
Sbjct: 669 LAPLPCTELSLGQHLLRA 686
>Hs17977656 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 778
Score = 76.3 bits (186), Expect = 5e-14
Identities = 42/106 (39%), Positives = 58/106 (54%), Gaps = 4/106 (3%)
Query: 17 PENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAV 76
P N C DC +A PRWAS +LG+ +CI+C+G HRS+G H SKV+S+ LDTW E L+ +
Sbjct: 409 PGNASCCDCGLAD-PRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLM 467
Query: 77 LEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQ---FIRTKYELKKWV 119
E G G P + + +IR KY +K+V
Sbjct: 468 CELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFV 513
>7300962 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 828
Score = 75.5 bits (184), Expect = 8e-14
Identities = 32/67 (47%), Positives = 48/67 (70%), Gaps = 1/67 (1%)
Query: 14 LRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHL 73
L+ P N C DC+ + PRWAS +LG+ +CI+C+G HRS+G H SKV+S+ LD W E++
Sbjct: 388 LKIPGNAYCCDCR-SPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLDAWESENV 446
Query: 74 EAVLEFG 80
+ ++E G
Sbjct: 447 KVMMELG 453
>Hs6806913 [T] KOG0703 Predicted GTPase-activating protein
Length = 374
Score = 74.7 bits (182), Expect = 1e-13
Identities = 44/119 (36%), Positives = 64/119 (52%), Gaps = 7/119 (5%)
Query: 5 EVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVD 64
E ++ + LL+ P N RC DC A P WAS++LGVF+C+ C+G HR++ +SKVKSV
Sbjct: 4 ERRRAVLELLQRPGNARCADCG-APDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVR 61
Query: 65 LDTWTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKI----GQFIRTKYELKKWV 119
LD W E +E + G + Y P S Q+IR KYE ++++
Sbjct: 62 LDAWEEAQVEFMASHG-NDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFI 119
>Hs20547911 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 550
Score = 73.9 bits (180), Expect = 2e-13
Identities = 41/138 (29%), Positives = 71/138 (50%), Gaps = 3/138 (2%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
+TS L ++ N+ C DC+ +P+WAS +LGV +CI+C+G HRS+GT +S+V
Sbjct: 322 LTSQSEAMALQSIQNMRGNSHCVDCETQ-NPKWASLNLGVLMCIECSGIHRSLGTRLSRV 380
Query: 61 KSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLG--GGTYVPDQSKIGQFIRTKYELKKW 118
+S++LD W E + + G G + + + ++IR+KYE K +
Sbjct: 381 RSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSIESTREEKERWIRSKYEHKLF 440
Query: 119 VGDDPIVDVKSSKHTAEA 136
+ P ++ +H A
Sbjct: 441 LAPLPCTELSLGQHLLRA 458
>Hs16799069 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 875
Score = 73.6 bits (179), Expect = 3e-13
Identities = 41/111 (36%), Positives = 59/111 (52%), Gaps = 3/111 (2%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLE 78
N+ C DC A +P WAS +LG +CI+C+G HR +G H+S+V+S+DLD W E L +
Sbjct: 638 NSFCIDCD-APNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTA 696
Query: 79 FGXXXXXXXXXXXXLGGGTYVPD--QSKIGQFIRTKYELKKWVGDDPIVDV 127
G G PD + + ++IR KYE K ++ P DV
Sbjct: 697 MGNALANSVWEGALGGYSKPGPDACREEKERWIRAKYEQKLFLAPLPSSDV 747
>At4g21160_1 [T] KOG0703 Predicted GTPase-activating protein
Length = 207
Score = 73.6 bits (179), Expect = 3e-13
Identities = 44/149 (29%), Positives = 70/149 (46%), Gaps = 37/149 (24%)
Query: 7 KKVLTTLLRDPENNRCGDCKVATHPRWA-------------------------------- 34
K+ + LL +N C DC A P+WA
Sbjct: 15 KRRIRDLLTQSDNRVCADCG-APDPKWALIECYDLVSLLVHFLVCFVFRKPIKLLVAYYR 73
Query: 35 SWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLG 94
S ++GVF+C+KC G HRS+G+HISKV SV LD W++E +++++E G +
Sbjct: 74 SANIGVFICLKCCGVHRSLGSHISKVLSVTLDEWSDEEVDSMIEIGGNASANSIYEAFIP 133
Query: 95 GGTYVP----DQSKIGQFIRTKYELKKWV 119
G+ P + +FIR+KYE ++++
Sbjct: 134 EGSSKPGPDASHDQRMRFIRSKYEHQEFL 162
>CE28116 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 1107
Score = 72.0 bits (175), Expect = 9e-13
Identities = 30/64 (46%), Positives = 43/64 (66%), Gaps = 1/64 (1%)
Query: 17 PENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAV 76
P N RC DC + WAS +LG+ +CI+C+G HR++G+HISKV+ ++LD W EHL +
Sbjct: 832 PGNGRCADCGNPSS-EWASINLGIIICIECSGIHRNLGSHISKVRGLELDQWPVEHLAVM 890
Query: 77 LEFG 80
G
Sbjct: 891 QAIG 894
>CE20232 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 903
Score = 72.0 bits (175), Expect = 9e-13
Identities = 30/64 (46%), Positives = 43/64 (66%), Gaps = 1/64 (1%)
Query: 17 PENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAV 76
P N RC DC + WAS +LG+ +CI+C+G HR++G+HISKV+ ++LD W EHL +
Sbjct: 628 PGNGRCADCGNPSS-EWASINLGIIICIECSGIHRNLGSHISKVRGLELDQWPVEHLAVM 686
Query: 77 LEFG 80
G
Sbjct: 687 QAIG 690
>CE19135 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 951
Score = 72.0 bits (175), Expect = 9e-13
Identities = 30/64 (46%), Positives = 43/64 (66%), Gaps = 1/64 (1%)
Query: 17 PENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAV 76
P N RC DC + WAS +LG+ +CI+C+G HR++G+HISKV+ ++LD W EHL +
Sbjct: 676 PGNGRCADCGNPSS-EWASINLGIIICIECSGIHRNLGSHISKVRGLELDQWPVEHLAVM 734
Query: 77 LEFG 80
G
Sbjct: 735 QAIG 738
>Hs8923763 [T] KOG0703 Predicted GTPase-activating protein
Length = 381
Score = 71.2 bits (173), Expect = 1e-12
Identities = 44/131 (33%), Positives = 67/131 (50%), Gaps = 9/131 (6%)
Query: 7 KKVLTTLLRDPE--NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVD 64
KK L LLR P+ N C DC A P WAS+ LG+F+C+ C G HR+ IS+VKSV
Sbjct: 8 KKRLLELLRAPDTGNAHCADCGAAD-PDWASYKLGIFICLNCCGVHRNF-PDISRVKSVR 65
Query: 65 LDTWTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSKI----GQFIRTKYELKKWVG 120
LD W + +E ++ G + Y+P + Q+IR KYE ++++
Sbjct: 66 LDFWDDSIVEFMIHNG-NLRVKAKFEARVPAFYYIPQANDCLVLKEQWIRAKYERREFMA 124
Query: 121 DDPIVDVKSSK 131
D + + ++
Sbjct: 125 DGETISLPGNR 135
>At2g37550 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator
Length = 456
Score = 71.2 bits (173), Expect = 1e-12
Identities = 31/61 (50%), Positives = 43/61 (69%), Gaps = 1/61 (1%)
Query: 10 LTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWT 69
L TL PEN C DC +P+WAS S G+F+C++C+G HR +G HIS V+SV +D+W+
Sbjct: 7 LRTLQSQPENKVCVDCS-QKNPQWASISYGIFMCLECSGKHRGLGVHISFVRSVTMDSWS 65
Query: 70 E 70
E
Sbjct: 66 E 66
>Hs20547087 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 439
Score = 70.9 bits (172), Expect = 2e-12
Identities = 41/138 (29%), Positives = 69/138 (49%), Gaps = 3/138 (2%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
+TS L ++ N C DC+ +P+WAS +LGV +CI+C+G HRS+GT +S+V
Sbjct: 211 LTSQSEAMALQSIQNMRGNAHCVDCETQ-NPKWASLNLGVLMCIECSGIHRSLGTRLSRV 269
Query: 61 KSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLG--GGTYVPDQSKIGQFIRTKYELKKW 118
+S++LD W E + + G G T + + ++IR+KYE K +
Sbjct: 270 RSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLF 329
Query: 119 VGDDPIVDVKSSKHTAEA 136
+ P ++ + A
Sbjct: 330 LAPLPCTELSLGQQLLRA 347
>HsM18034686 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 836
Score = 70.5 bits (171), Expect = 3e-12
Identities = 37/98 (37%), Positives = 53/98 (53%), Gaps = 3/98 (3%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLE 78
N+ C DC A +P WAS +LG +CI+C+G HR++GTH+S+V+S+DLD W E +
Sbjct: 587 NSICVDCG-APNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTA 645
Query: 79 FGXXXXXXXXXXXXLGGGTYVPDQSKIGQ--FIRTKYE 114
G G D S+ + +IR KYE
Sbjct: 646 IGNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYE 683
>Hs7661962 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 836
Score = 70.5 bits (171), Expect = 3e-12
Identities = 37/98 (37%), Positives = 53/98 (53%), Gaps = 3/98 (3%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLE 78
N+ C DC A +P WAS +LG +CI+C+G HR++GTH+S+V+S+DLD W E +
Sbjct: 587 NSICVDCG-APNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTA 645
Query: 79 FGXXXXXXXXXXXXLGGGTYVPDQSKIGQ--FIRTKYE 114
G G D S+ + +IR KYE
Sbjct: 646 IGNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYE 683
>SPCC622.14 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator
Length = 309
Score = 69.3 bits (168), Expect = 6e-12
Identities = 31/71 (43%), Positives = 48/71 (66%), Gaps = 2/71 (2%)
Query: 10 LTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWT 69
L L R PEN +C DC A +P+WAS +LG+F+C+ C+G HR +G S V+S+ +D W+
Sbjct: 5 LDQLTRLPENKKCFDCD-APNPQWASCNLGIFICLDCSGQHRGLGVEKSFVRSITMDNWS 63
Query: 70 EEHLEAVLEFG 80
E ++ ++E G
Sbjct: 64 ERQVK-MMEVG 73
>Hs22051953 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 663
Score = 69.3 bits (168), Expect = 6e-12
Identities = 40/138 (28%), Positives = 69/138 (49%), Gaps = 3/138 (2%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
+TS L ++ N C DC+ +P+WAS +LGV +CI+C+G HRS+GT +S+V
Sbjct: 435 LTSQSEAMALQSIQNMRGNAHCVDCETQ-NPKWASLNLGVLMCIECSGIHRSLGTRLSRV 493
Query: 61 KSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLG--GGTYVPDQSKIGQFIRTKYELKKW 118
+S++LD W E + + G G + + + ++IR+KYE K +
Sbjct: 494 RSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLF 553
Query: 119 VGDDPIVDVKSSKHTAEA 136
+ P ++ + A
Sbjct: 554 LAPLPCTELSLGQQLLRA 571
>Hs19263343 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 663
Score = 69.3 bits (168), Expect = 6e-12
Identities = 40/138 (28%), Positives = 69/138 (49%), Gaps = 3/138 (2%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
+TS L ++ N C DC+ +P+WAS +LGV +CI+C+G HRS+GT +S+V
Sbjct: 435 LTSQSKAMALQSIQNMRGNAHCVDCETQ-NPKWASLNLGVLMCIECSGIHRSLGTRLSRV 493
Query: 61 KSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLG--GGTYVPDQSKIGQFIRTKYELKKW 118
+S++LD W E + + G G + + + ++IR+KYE K +
Sbjct: 494 RSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLF 553
Query: 119 VGDDPIVDVKSSKHTAEA 136
+ P ++ + A
Sbjct: 554 LAPLPCTELSLGQQLLRA 571
>CE11618 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator
Length = 423
Score = 69.3 bits (168), Expect = 6e-12
Identities = 30/73 (41%), Positives = 48/73 (65%), Gaps = 1/73 (1%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
M S ++VL L +NN C +C+ A +P+W S S G+++C++C+G HRS+G H+S V
Sbjct: 1 MASPRTRRVLKELRPCDDNNFCFECE-ANNPQWVSVSYGIWICLECSGIHRSLGVHLSFV 59
Query: 61 KSVDLDTWTEEHL 73
+SV +D W + L
Sbjct: 60 RSVTMDKWKDIEL 72
>At3g53710 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator
Length = 459
Score = 69.3 bits (168), Expect = 6e-12
Identities = 30/60 (50%), Positives = 42/60 (70%), Gaps = 1/60 (1%)
Query: 10 LTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWT 69
L TL PEN C DC +P+WAS S G+F+C++C+G HR +G HIS V+SV +D+W+
Sbjct: 7 LRTLQSQPENKVCVDC-AQKNPQWASVSYGIFMCLECSGKHRGLGVHISFVRSVTMDSWS 65
>At5g61980 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 850
Score = 68.9 bits (167), Expect = 7e-12
Identities = 32/63 (50%), Positives = 43/63 (67%), Gaps = 1/63 (1%)
Query: 4 VEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSV 63
V+ +K + L R N RC DC A P WAS +LGV +CI+C+G HR++G HISKV+S+
Sbjct: 517 VKTEKPIDVLTRVLGNERCADCG-APEPDWASLNLGVLICIECSGIHRNLGVHISKVRSL 575
Query: 64 DLD 66
LD
Sbjct: 576 TLD 578
>At1g60860 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 776
Score = 68.9 bits (167), Expect = 7e-12
Identities = 32/58 (55%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
Query: 9 VLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
VLT L P NN C +C A P WAS +LGV +CI+C+G HR++G HISKV+S+ LD
Sbjct: 469 VLTILREIPGNNTCAECN-APDPDWASLNLGVLMCIECSGVHRNLGVHISKVRSLTLD 525
>7294580 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator
Length = 468
Score = 68.9 bits (167), Expect = 7e-12
Identities = 31/75 (41%), Positives = 49/75 (65%), Gaps = 3/75 (4%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATH-PRWASWSLGVFVCIKCAGFHRSMGTHISK 59
M S ++VL L EN++C +C TH P+W S + G+++C++C+G HRS+G H+S
Sbjct: 1 MASPRTRRVLQELKPQDENSKCFEC--GTHNPQWVSVTYGIWICLECSGKHRSLGVHLSF 58
Query: 60 VKSVDLDTWTEEHLE 74
V+SV +D W + LE
Sbjct: 59 VRSVTMDKWKDIELE 73
>Hs7661880 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 740
Score = 68.6 bits (166), Expect = 1e-11
Identities = 30/62 (48%), Positives = 43/62 (68%), Gaps = 1/62 (1%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLE 78
N +C DC+ P WAS +LGV +CI+C+G HRS+G H SKV+S+ LD+W E ++ + E
Sbjct: 417 NAQCCDCREPA-PEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCE 475
Query: 79 FG 80
G
Sbjct: 476 LG 477
>Hs22051029 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 663
Score = 68.6 bits (166), Expect = 1e-11
Identities = 40/138 (28%), Positives = 69/138 (49%), Gaps = 3/138 (2%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
+TS L ++ N C D + +P+WAS +LGV +CI+C+G HRS+GT +S+V
Sbjct: 435 LTSQSEAMALQSIQNMRGNAHCVDYETQ-NPKWASLNLGVLMCIECSGIHRSLGTRLSRV 493
Query: 61 KSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLG--GGTYVPDQSKIGQFIRTKYELKKW 118
+S++LD W E + + G G + + + ++IR+KYE K +
Sbjct: 494 RSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLF 553
Query: 119 VGDDPIVDVKSSKHTAEA 136
+ P ++ +H A
Sbjct: 554 LAPLPCTELSLGQHLLRA 571
>Hs22052038 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 457
Score = 67.8 bits (164), Expect = 2e-11
Identities = 40/138 (28%), Positives = 67/138 (47%), Gaps = 3/138 (2%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
+TS L ++ N C DC+ +P+WAS +LGV +CI+C+G HRS GT +S+V
Sbjct: 257 LTSQSEAMALQSIQNMRGNAHCVDCETQ-NPKWASLNLGVLMCIECSGIHRSFGTRLSRV 315
Query: 61 KSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLG--GGTYVPDQSKIGQFIRTKYELKKW 118
+S++LD W E + + G G + + + +IR+KYE K +
Sbjct: 316 RSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLF 375
Query: 119 VGDDPIVDVKSSKHTAEA 136
+ P ++ + A
Sbjct: 376 LAPLPCTELSLGQQLLRA 393
>Hs20543681 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 485
Score = 67.8 bits (164), Expect = 2e-11
Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 3/138 (2%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
+TS L ++ N C DC+ +P+WAS +LGV +CI+C+G HRS+GT +S+V
Sbjct: 257 LTSQSEAMALQSIQNMRGNAHCVDCETQ-NPKWASLNLGVLMCIECSGIHRSLGTRLSRV 315
Query: 61 KSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLG--GGTYVPDQSKIGQFIRTKYELKKW 118
+S++LD W E + + G G + + + ++I +KYE K +
Sbjct: 316 RSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKERWIHSKYEEKLF 375
Query: 119 VGDDPIVDVKSSKHTAEA 136
+ P ++ + A
Sbjct: 376 LAPLPCTELSLGQQLLRA 393
>Hs8922652 [TUZ] KOG0704 ADP-ribosylation factor GTPase activator
Length = 406
Score = 67.4 bits (163), Expect = 2e-11
Identities = 30/74 (40%), Positives = 47/74 (62%), Gaps = 1/74 (1%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
M S +KVL + ENN C +C A +P+W S + G+++C++C+G HR +G H+S V
Sbjct: 1 MASPRTRKVLKEVRVQDENNVCFECG-AFNPQWVSVTYGIWICLECSGRHRGLGVHLSFV 59
Query: 61 KSVDLDTWTEEHLE 74
+SV +D W + LE
Sbjct: 60 RSVTMDKWKDIELE 73
>At2g35210 [T] KOG0706 Predicted GTPase-activating protein
Length = 395
Score = 67.4 bits (163), Expect = 2e-11
Identities = 31/72 (43%), Positives = 45/72 (62%), Gaps = 1/72 (1%)
Query: 9 VLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTW 68
V L +N C DC A +P WAS + G+F+CI C+ HRS+G HIS V+S +LD+W
Sbjct: 12 VFKKLKAKSDNKICFDCN-AKNPTWASVTYGIFLCIDCSAVHRSLGVHISFVRSTNLDSW 70
Query: 69 TEEHLEAVLEFG 80
+ E L+ ++ G
Sbjct: 71 SSEQLKMMIYGG 82
>At1g10870 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 531
Score = 67.4 bits (163), Expect = 2e-11
Identities = 31/58 (53%), Positives = 43/58 (73%), Gaps = 2/58 (3%)
Query: 10 LTTLLRD-PENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
++T+LR P NN C +C A P WAS +LGV +CI+C+G HR++G HISKV+S+ LD
Sbjct: 225 VSTILRGLPGNNACAECN-APEPDWASLNLGVLLCIQCSGVHRNLGVHISKVRSLSLD 281
>Hs22053338 [T] KOG0705 GTPase-activating protein Centaurin gamma (contains
Ras-like GTPase PH and ankyrin repeat domains)
Length = 663
Score = 67.0 bits (162), Expect = 3e-11
Identities = 38/129 (29%), Positives = 66/129 (50%), Gaps = 3/129 (2%)
Query: 1 MTSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV 60
+TS L ++ N C DC+ +P+WAS +LGV +CI+C+G H S+GT +S+V
Sbjct: 435 LTSQSEAMALQSIQNMRGNAHCVDCETQ-NPKWASLNLGVLMCIECSGIHHSLGTRLSRV 493
Query: 61 KSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLG--GGTYVPDQSKIGQFIRTKYELKKW 118
+S++LD W E + + G G + + + ++IR+KYE K +
Sbjct: 494 RSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLF 553
Query: 119 VGDDPIVDV 127
+ P ++
Sbjct: 554 LAPLPCTEL 562
>At5g46750 [T] KOG0706 Predicted GTPase-activating protein
Length = 402
Score = 67.0 bits (162), Expect = 3e-11
Identities = 31/69 (44%), Positives = 42/69 (59%), Gaps = 1/69 (1%)
Query: 9 VLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTW 68
V L EN C DC A +P WAS G+F+CI C+ HRS+G HIS V+S +LD+W
Sbjct: 12 VFRKLKSKSENKVCFDCS-AKNPTWASVPYGIFLCIDCSAVHRSLGVHISFVRSTNLDSW 70
Query: 69 TEEHLEAVL 77
+ E L ++
Sbjct: 71 SPEQLRTMM 79
>At4g17890_1 [T] KOG0706 Predicted GTPase-activating protein
Length = 538
Score = 66.2 bits (160), Expect = 5e-11
Identities = 30/69 (43%), Positives = 43/69 (61%), Gaps = 1/69 (1%)
Query: 9 VLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTW 68
V L EN C DC A +P WAS + G+F+CI C+ HR++G HIS V+S +LD+W
Sbjct: 15 VFRKLKSKSENKVCFDCS-AKNPTWASVTYGIFLCIDCSATHRNLGVHISFVRSTNLDSW 73
Query: 69 TEEHLEAVL 77
+ E L ++
Sbjct: 74 SPEQLRTMM 82
>At5g13300 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 750
Score = 64.7 bits (156), Expect = 1e-10
Identities = 30/60 (50%), Positives = 42/60 (70%), Gaps = 1/60 (1%)
Query: 7 KKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
+K + L + N++C DC A P WAS +LGV VCI+C+G HR++G HISKV+S+ LD
Sbjct: 424 EKPIDALRKVCGNDKCADCG-APEPDWASLNLGVLVCIECSGVHRNLGVHISKVRSLTLD 482
>YDR524c [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 482
Score = 64.3 bits (155), Expect = 2e-10
Identities = 38/112 (33%), Positives = 55/112 (48%), Gaps = 6/112 (5%)
Query: 16 DPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEA 75
D N +C DC W S +L +CIKC+G HRS+G+HISK++S+ LD +T L
Sbjct: 180 DKSNLKCCDCGSTATVEWVSINLLCILCIKCSGVHRSLGSHISKIRSLTLDNFTSLELMH 239
Query: 76 VLEFGXXXXXXXXXXXX------LGGGTYVPDQSKIGQFIRTKYELKKWVGD 121
+L+ + T D S+ +FI KY+ KK+V D
Sbjct: 240 LLQNNVSNSNVNAIYESNLRNFPVKKITANSDDSERSKFIIDKYQFKKFVID 291
>Hs21264337_1 [TZ] KOG1117 Rho- and Arf-GTPase activating protein ARAP3
Length = 1348
Score = 63.9 bits (154), Expect = 2e-10
Identities = 37/101 (36%), Positives = 55/101 (53%), Gaps = 5/101 (4%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDT--WTEEHLEAV 76
N +C DC ++ P WA+ +LGV +C +CAG HR++G+ ISKV+S+ LDT W+ E ++
Sbjct: 501 NRQCADCG-SSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLF 559
Query: 77 LEFGXXXXXXXXXXXXLGGGTYVPDQS--KIGQFIRTKYEL 115
+ G G PD + G+FI KY L
Sbjct: 560 IVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRL 600
>7296565 [T] KOG0706 Predicted GTPase-activating protein
Length = 552
Score = 63.5 bits (153), Expect = 3e-10
Identities = 28/66 (42%), Positives = 42/66 (63%), Gaps = 2/66 (3%)
Query: 5 EVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVD 64
E++ V + L P N C DC A P W+S + G+F+CI C+ HR++G H++ V+S +
Sbjct: 12 EIESVFSRLRAQPANKSCFDC-AAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTN 70
Query: 65 LDT-WT 69
LDT WT
Sbjct: 71 LDTNWT 76
>At2g14490 [T] KOG0703 Predicted GTPase-activating protein
Length = 142
Score = 63.2 bits (152), Expect = 4e-10
Identities = 31/74 (41%), Positives = 46/74 (61%), Gaps = 3/74 (4%)
Query: 7 KKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
K+ + LL P+N C DC A+ P+WA + +K G HRS+GTHI KV SV LD
Sbjct: 15 KRRIRDLLNQPDNRVCADCG-ASVPKWAKYQS--IHLLKSCGVHRSLGTHILKVLSVTLD 71
Query: 67 TWTEEHLEAVLEFG 80
W++E +++++E G
Sbjct: 72 EWSDEEVDSMIETG 85
>7304095 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 1019
Score = 63.2 bits (152), Expect = 4e-10
Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 5/107 (4%)
Query: 17 PENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAV 76
P N+RC DC W S + G+ VCI+C+G HR +G H S+++S+ LD T +L
Sbjct: 416 PGNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVHHSRIQSLTLDNLTTANLLIA 475
Query: 77 LEFGXXXXXXXXXXXXLGGGTYVPDQSKIGQ----FIRTKYELKKWV 119
G LG G + S + FIR KY K++V
Sbjct: 476 RAMG-NSTLNDIMEAKLGRGKLQHESSMYVEERYDFIRAKYVAKRYV 521
>Hs22065234 [T] KOG0706 Predicted GTPase-activating protein
Length = 521
Score = 62.8 bits (151), Expect = 5e-10
Identities = 28/63 (44%), Positives = 41/63 (64%), Gaps = 1/63 (1%)
Query: 5 EVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVD 64
E++ + L P N C DC A +P WAS + GVF+CI C+G HRS+G H+S ++S +
Sbjct: 9 EIQTLFKRLRAVPTNKACFDCG-AKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTE 67
Query: 65 LDT 67
LD+
Sbjct: 68 LDS 70
>SPAC22E12.17c [T] KOG0706 Predicted GTPase-activating protein
Length = 486
Score = 62.4 bits (150), Expect = 7e-10
Identities = 31/78 (39%), Positives = 47/78 (59%), Gaps = 4/78 (5%)
Query: 2 TSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKV- 60
T E +K+LT+L +N C DC A +P W+S + G+++C+ C+ HR+MG HIS V
Sbjct: 4 TKEESQKLLTSLRSQRDNKVCFDCG-AKNPTWSSTTFGIYLCLDCSAAHRNMGVHISFVR 62
Query: 61 --KSVDLDTWTEEHLEAV 76
+S LD+WT L +
Sbjct: 63 FLRSTVLDSWTYAQLRVM 80
>Hs22047742 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 652
Score = 62.4 bits (150), Expect = 7e-10
Identities = 26/60 (43%), Positives = 41/60 (68%), Gaps = 1/60 (1%)
Query: 7 KKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
K ++ + R P N+ C DC ++ P W S +LG+ CI+C+G HR MG HIS+++S++LD
Sbjct: 19 KAIIEDVQRLPGNDICCDCG-SSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELD 77
>ECU11g0550 [T] KOG0706 Predicted GTPase-activating protein
Length = 250
Score = 62.4 bits (150), Expect = 7e-10
Identities = 29/64 (45%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 8 KVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDT 67
K + L EN +C DC A P W S + G+F+C CA HRS+G S VKSV+LD
Sbjct: 7 KEVKALREIEENKKCADCS-APSPPWTSVTYGIFICFDCASVHRSLGVKTSFVKSVNLDI 65
Query: 68 WTEE 71
W E+
Sbjct: 66 WDEK 69
>YDL226c [TUZ] KOG0704 ADP-ribosylation factor GTPase activator
Length = 352
Score = 62.0 bits (149), Expect = 9e-10
Identities = 27/69 (39%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Query: 5 EVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVD 64
+ ++ L L + N +C DC A +P+WA+ G F+C++CAG HR +G HIS V+S+
Sbjct: 9 DTRRRLLQLQKIGANKKCMDCG-APNPQWATPKFGAFICLECAGIHRGLGVHISFVRSIT 67
Query: 65 LDTWTEEHL 73
+D + E L
Sbjct: 68 MDQFKPEEL 76
>Hs14150223 [T] KOG0706 Predicted GTPase-activating protein
Length = 521
Score = 62.0 bits (149), Expect = 9e-10
Identities = 28/63 (44%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Query: 5 EVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVD 64
E++ + L P N C DC A +P WAS GVF+CI C+G HRS+G H+S ++S +
Sbjct: 9 EIQTLFKRLRAVPTNKACFDCG-AKNPSWASIMYGVFLCIDCSGVHRSLGVHLSFIRSTE 67
Query: 65 LDT 67
LD+
Sbjct: 68 LDS 70
>Hs20070255 [T] KOG0706 Predicted GTPase-activating protein
Length = 516
Score = 60.1 bits (144), Expect = 3e-09
Identities = 27/63 (42%), Positives = 40/63 (62%), Gaps = 1/63 (1%)
Query: 5 EVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVD 64
++ + L P N C DC A +P WAS + GVF+CI C+G HRS+G H+S ++S +
Sbjct: 8 DILTIFKRLRSVPTNKVCFDCG-AKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTE 66
Query: 65 LDT 67
LD+
Sbjct: 67 LDS 69
>SPBC17G9.08c [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 870
Score = 59.7 bits (143), Expect = 4e-09
Identities = 36/128 (28%), Positives = 59/128 (45%), Gaps = 13/128 (10%)
Query: 22 CGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLEFGX 81
C DC W + + V +CI C+G HRS+GTHI+K++S+ LD + E ++ + G
Sbjct: 686 CADCNTTARVEWCAINFPVVLCIDCSGIHRSLGTHITKIRSLTLDKFNPETVDLLYATGN 745
Query: 82 XXXXXXXXXXXLGGGT-----YVPDQSKIGQFIRTKYELKKWV----GDDPIVDVKSSKH 132
GG T +Q + QF++ KY K+++ DP + S
Sbjct: 746 SFVNEIYE----GGITDWKIKNFENQERRVQFVKDKYLYKRFIKSSFSHDPNTGLLESIE 801
Query: 133 TAEAKDRV 140
+ K+ V
Sbjct: 802 HSNLKEAV 809
>ECU08g1690 [T] KOG0706 Predicted GTPase-activating protein
Length = 266
Score = 58.9 bits (141), Expect = 8e-09
Identities = 37/113 (32%), Positives = 50/113 (43%), Gaps = 19/113 (16%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLE 78
N RC DC + P W + + G F+C +CA HR +G +KVKS LDTW+ L V
Sbjct: 39 NKRCADCNNPS-PIWVTVTYGFFICTECAAKHRELGVGTTKVKSTILDTWSLSELRRV-- 95
Query: 79 FGXXXXXXXXXXXXLGGGTYVPDQSKIGQFIRTKYELKKWVGDDPIVDVKSSK 131
+ G + P K+ +RTKY W +VD S K
Sbjct: 96 -------------YVSGNSNAPKLGKVTD-LRTKYTKAAWY--SKVVDELSGK 132
>YER122c [T] KOG0706 Predicted GTPase-activating protein
Length = 493
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/72 (41%), Positives = 40/72 (54%), Gaps = 1/72 (1%)
Query: 2 TSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVK 61
T ++V L + EN C DC +P W S GV +CI+C+ HR+MG HI+ VK
Sbjct: 11 TEQTTQQVFQKLGSNMENRVCFDCG-NKNPTWTSVPFGVMLCIQCSAVHRNMGVHITFVK 69
Query: 62 SVDLDTWTEEHL 73
S LD WT +L
Sbjct: 70 SSTLDKWTINNL 81
>CE28110 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 826
Score = 58.5 bits (140), Expect = 1e-08
Identities = 28/66 (42%), Positives = 41/66 (61%), Gaps = 1/66 (1%)
Query: 15 RDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLE 74
R P N C DC + P+W S +LGV +CI+C+G HRS+G SKV+S+ +D+ E +
Sbjct: 455 RVPGNEVCADCG-SPAPKWVSINLGVVLCIECSGAHRSLGVQTSKVRSLCMDSIDNELRD 513
Query: 75 AVLEFG 80
+L G
Sbjct: 514 VLLALG 519
>CE25223 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 742
Score = 58.5 bits (140), Expect = 1e-08
Identities = 28/66 (42%), Positives = 41/66 (61%), Gaps = 1/66 (1%)
Query: 15 RDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLE 74
R P N C DC + P+W S +LGV +CI+C+G HRS+G SKV+S+ +D+ E +
Sbjct: 371 RVPGNEVCADCG-SPAPKWVSINLGVVLCIECSGAHRSLGVQTSKVRSLCMDSIDNELRD 429
Query: 75 AVLEFG 80
+L G
Sbjct: 430 VLLALG 435
>CE01896 [T] KOG0706 Predicted GTPase-activating protein
Length = 1159
Score = 58.5 bits (140), Expect = 1e-08
Identities = 28/76 (36%), Positives = 46/76 (59%), Gaps = 2/76 (2%)
Query: 2 TSVEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVK 61
+ V+++ + + P N C DC A +P W + + GVF+CI C+ HR++G H++ V+
Sbjct: 8 SKVDLQTAMRKMRALPPNKLCFDCG-ARNPTWCTVTYGVFLCIDCSAVHRNLGVHLTFVR 66
Query: 62 SVDLDT-WTEEHLEAV 76
S +LDT WT L A+
Sbjct: 67 STNLDTNWTWLQLRAM 82
>SPAC26A3.10 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 923
Score = 58.2 bits (139), Expect = 1e-08
Identities = 25/65 (38%), Positives = 40/65 (61%)
Query: 16 DPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEA 75
D N+ C DC W S ++ V +CI+C+G HRS+GTHISK +S+ LD+ +++
Sbjct: 724 DVSNSVCADCGSVKDVTWCSINIPVVLCIECSGIHRSLGTHISKTRSLLLDSLSQQSKVL 783
Query: 76 VLEFG 80
+ + G
Sbjct: 784 LCKIG 788
>HsM16975482 [TZ] KOG1117 Rho- and Arf-GTPase activating protein ARAP3
Length = 1704
Score = 58.2 bits (139), Expect = 1e-08
Identities = 30/64 (46%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDT--WTEEHLEAV 76
N C DCK A P WAS +L V +C KCAG HRS+G SKV+S+ +D W+ E +E
Sbjct: 697 NRSCADCK-APDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELF 755
Query: 77 LEFG 80
+ G
Sbjct: 756 IVIG 759
>Hs21264597 [TZ] KOG1117 Rho- and Arf-GTPase activating protein ARAP3
Length = 1205
Score = 58.2 bits (139), Expect = 1e-08
Identities = 29/64 (45%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD--TWTEEHLEAV 76
N C DC A P WAS +L V +C +CAG HR +G +SKV+S+ +D WTE +E
Sbjct: 302 NRFCADCG-APQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELF 360
Query: 77 LEFG 80
L+ G
Sbjct: 361 LQLG 364
>Hs21264592 [TZ] KOG1117 Rho- and Arf-GTPase activating protein ARAP3
Length = 1704
Score = 58.2 bits (139), Expect = 1e-08
Identities = 30/64 (46%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDT--WTEEHLEAV 76
N C DCK A P WAS +L V +C KCAG HRS+G SKV+S+ +D W+ E +E
Sbjct: 697 NRSCADCK-APDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELF 755
Query: 77 LEFG 80
+ G
Sbjct: 756 IVIG 759
>Hs16975484 [TZ] KOG1117 Rho- and Arf-GTPase activating protein ARAP3
Length = 1210
Score = 58.2 bits (139), Expect = 1e-08
Identities = 29/64 (45%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 19 NNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD--TWTEEHLEAV 76
N C DC A P WAS +L V +C +CAG HR +G +SKV+S+ +D WTE +E
Sbjct: 307 NRFCADCG-APQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELF 365
Query: 77 LEFG 80
L+ G
Sbjct: 366 LQLG 369
>YGL181w_1 [T] KOG0703 Predicted GTPase-activating protein
Length = 182
Score = 57.8 bits (138), Expect = 2e-08
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 9/125 (7%)
Query: 6 VKKVLTTLLRDPEN-NRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSM-----GTHISK 59
V + L L+ EN N+CG+C +P W S +LGVF+C +CA HR + S
Sbjct: 13 VDRELKELINSSENANKCGECG-NFYPTWCSVNLGVFLCGRCASVHRKVFGSRDDDAFSN 71
Query: 60 VKSVDLDTWTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQSK--IGQFIRTKYELKK 117
VKS+ +D WT E ++ ++ G + D K + +IR KY L K
Sbjct: 72 VKSLSMDRWTREDIDELVSLGGNKGNARFWNPKNVPFPFDGDDDKAIVEHYIRDKYILGK 131
Query: 118 WVGDD 122
+ D+
Sbjct: 132 FRYDE 136
>YNL204c [TUZ] KOG0704 ADP-ribosylation factor GTPase activator
Length = 300
Score = 57.4 bits (137), Expect = 2e-08
Identities = 28/77 (36%), Positives = 46/77 (59%), Gaps = 1/77 (1%)
Query: 4 VEVKKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSV 63
+E +K L + NN C +CK + +P++ S S G+F+C+ CA R MGT+I VKS+
Sbjct: 10 MENRKRLLRAKKAAGNNNCFECK-SVNPQFVSCSFGIFICVNCANLLRGMGTNIFCVKSI 68
Query: 64 DLDTWTEEHLEAVLEFG 80
+D + E+ + V + G
Sbjct: 69 TMDNFEEKDVRRVEKSG 85
>Hs4502249 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 1006
Score = 56.2 bits (134), Expect = 5e-08
Identities = 24/60 (40%), Positives = 39/60 (65%), Gaps = 1/60 (1%)
Query: 7 KKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
K++++ + R N+ C DC A P W S +LG+ CI+C+G HR +G H S+++S+ LD
Sbjct: 421 KEIISEVQRMTGNDVCCDCG-APDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLD 479
>Hs19923540 [T] KOG0521 Putative GTPase activating proteins (GAPs)
Length = 903
Score = 55.8 bits (133), Expect = 6e-08
Identities = 27/74 (36%), Positives = 40/74 (53%), Gaps = 1/74 (1%)
Query: 7 KKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
K ++ + P N++C DC A P W S +LGV CI+C+G HR +G S+++S+ LD
Sbjct: 426 KLLIAEVKSRPGNSQCCDCGAAD-PTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 484
Query: 67 TWTEEHLEAVLEFG 80
L L G
Sbjct: 485 LLGPSELLLALNMG 498
>Hs4758562 [T] KOG0702 Predicted GTPase-activating protein
Length = 562
Score = 55.1 bits (131), Expect = 1e-07
Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 5/130 (3%)
Query: 8 KVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDT 67
K+L + P N +C DC P + + ++G FVC C+G R + +VKS+ + T
Sbjct: 15 KMLRDMTGLPRNRKCFDCD-QRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTT 72
Query: 68 WTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPD---QSKIGQFIRTKYELKKWVGDDPI 124
+T++ +E + + G + +PD K+ +F++ KYE K+W
Sbjct: 73 FTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQ 132
Query: 125 VDVKSSKHTA 134
V +S H +
Sbjct: 133 AKVVASVHAS 142
>Hs7661712 [T] KOG0818 GTPase-activating proteins of the GIT family
Length = 761
Score = 54.3 bits (129), Expect = 2e-07
Identities = 37/115 (32%), Positives = 47/115 (40%), Gaps = 11/115 (9%)
Query: 15 RDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLE 74
+ P C DC A P WAS S GV VC +C HRS+G HIS VK + W L+
Sbjct: 4 KGPRAEVCADCS-APDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQ 62
Query: 75 AVLEFGXXXXXXXXXXXXL------GGGTYVPDQSKI----GQFIRTKYELKKWV 119
V L G Q K+ +FIR KY++ +V
Sbjct: 63 MVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFV 117
>HsM7661944 [T] KOG0818 GTPase-activating proteins of the GIT family
Length = 471
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/137 (28%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
Query: 22 CGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLEFGX 81
C DC P WAS + G F+C +C HRS+G HIS+V+ + W L+ V
Sbjct: 11 CADCS-GPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYN 69
Query: 82 XXXXXXXXXXXLGGGTYVPDQSKI----------GQFIRTKYELKKWVGDDPIVDVKSSK 131
L + + + K +FIR KY++ +V P D S
Sbjct: 70 NGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDS-- 127
Query: 132 HTAEAKDRVAQKAAAVR 148
AKD Q ++VR
Sbjct: 128 --VTAKDLSKQLHSSVR 142
>Hs21237794 [T] KOG0818 GTPase-activating proteins of the GIT family
Length = 471
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/137 (28%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
Query: 22 CGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLEFGX 81
C DC P WAS + G F+C +C HRS+G HIS+V+ + W L+ V
Sbjct: 11 CADCS-GPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYN 69
Query: 82 XXXXXXXXXXXLGGGTYVPDQSKI----------GQFIRTKYELKKWVGDDPIVDVKSSK 131
L + + + K +FIR KY++ +V P D S
Sbjct: 70 NGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDS-- 127
Query: 132 HTAEAKDRVAQKAAAVR 148
AKD Q ++VR
Sbjct: 128 --VTAKDLSKQLHSSVR 142
>Hs21237786 [T] KOG0818 GTPase-activating proteins of the GIT family
Length = 679
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/137 (28%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
Query: 22 CGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLEFGX 81
C DC P WAS + G F+C +C HRS+G HIS+V+ + W L+ V
Sbjct: 11 CADCS-GPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYN 69
Query: 82 XXXXXXXXXXXLGGGTYVPDQSKI----------GQFIRTKYELKKWVGDDPIVDVKSSK 131
L + + + K +FIR KY++ +V P D S
Sbjct: 70 NGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDS-- 127
Query: 132 HTAEAKDRVAQKAAAVR 148
AKD Q ++VR
Sbjct: 128 --VTAKDLSKQLHSSVR 142
>Hs17149832 [T] KOG0818 GTPase-activating proteins of the GIT family
Length = 631
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/137 (28%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
Query: 22 CGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLEFGX 81
C DC P WAS + G F+C +C HRS+G HIS+V+ + W L+ V
Sbjct: 11 CADCS-GPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYN 69
Query: 82 XXXXXXXXXXXLGGGTYVPDQSKI----------GQFIRTKYELKKWVGDDPIVDVKSSK 131
L + + + K +FIR KY++ +V P D S
Sbjct: 70 NGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDS-- 127
Query: 132 HTAEAKDRVAQKAAAVR 148
AKD Q ++VR
Sbjct: 128 --VTAKDLSKQLHSSVR 142
>Hs17149830 [T] KOG0818 GTPase-activating proteins of the GIT family
Length = 759
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/137 (28%), Positives = 56/137 (40%), Gaps = 15/137 (10%)
Query: 22 CGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLEFGX 81
C DC P WAS + G F+C +C HRS+G HIS+V+ + W L+ V
Sbjct: 11 CADCS-GPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYN 69
Query: 82 XXXXXXXXXXXLGGGTYVPDQSKI----------GQFIRTKYELKKWVGDDPIVDVKSSK 131
L + + + K +FIR KY++ +V P D S
Sbjct: 70 NGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDS-- 127
Query: 132 HTAEAKDRVAQKAAAVR 148
AKD Q ++VR
Sbjct: 128 --VTAKDLSKQLHSSVR 142
>7303716 [T] KOG0818 GTPase-activating proteins of the GIT family
Length = 695
Score = 51.6 bits (122), Expect = 1e-06
Identities = 28/76 (36%), Positives = 33/76 (42%), Gaps = 1/76 (1%)
Query: 22 CGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLDTWTEEHLEAVLEFGX 81
CGDC A P WAS + G+ +C C HRS+G HIS VKS+ W L V
Sbjct: 13 CGDCG-AGDPSWASINRGILLCADCCSVHRSLGRHISIVKSLRQGNWEPSVLNFVNSLNA 71
Query: 82 XXXXXXXXXXXLGGGT 97
L G T
Sbjct: 72 HGANSVWEHHLLDGST 87
>At1g08680 [T] KOG0702 Predicted GTPase-activating protein
Length = 159
Score = 50.1 bits (118), Expect = 4e-06
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 7 KKVLTTLLRDPENNRCGDCKVATHPRWASWSLGVFVCIKCAGFHRSMGTHISKVKSVDLD 66
+K++ L++ P N RC +C + P++ + FVC+ C+G HR TH +VKSV +
Sbjct: 12 EKIIRGLMKLPPNRRCINCN-SLGPQYVCTTFWTFVCMACSGIHREF-TH--RVKSVSMS 67
Query: 67 TWTEEHLEAVLEFGXXXXXXXXXXXXLGGGTYVPDQS---KIGQFIRTKYELKKWVG 120
+T + +E + G +P+ S ++ +FI+ Y KK+ G
Sbjct: 68 KFTSKEVEVLQNGGNQRAREIYLKNWDHQRQRLPENSNAERVREFIKNVYVQKKYAG 124
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.129 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,089,833
Number of Sequences: 60738
Number of extensions: 410068
Number of successful extensions: 836
Number of sequences better than 1.0e-05: 85
Number of HSP's better than 0.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 736
Number of HSP's gapped (non-prelim): 87
length of query: 279
length of database: 30,389,216
effective HSP length: 105
effective length of query: 174
effective length of database: 24,011,726
effective search space: 4178040324
effective search space used: 4178040324
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)