ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7347 good HC KOG0534 Coenzyme transport and metabolism NADH-cytochrome b-5 reductase
r_klactVI7347 good HC KOG0534 Energy production and conversion NADH-cytochrome b-5 reductase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7347 2560900 2560058 -281
(281 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL043c [HC] KOG0534 NADH-cytochrome b-5 reductase 332 4e-91
SPCC970.03 [HC] KOG0534 NADH-cytochrome b-5 reductase 262 4e-70
At5g17770 [HC] KOG0534 NADH-cytochrome b-5 reductase 251 8e-67
YML125c [HC] KOG0534 NADH-cytochrome b-5 reductase 201 1e-51
Hs7706443 [HC] KOG0534 NADH-cytochrome b-5 reductase 197 1e-50
YML087c [HC] KOG0534 NADH-cytochrome b-5 reductase 191 1e-48
At1g77760_3 [HC] KOG0534 NADH-cytochrome b-5 reductase 187 1e-47
Hs14735899 [HC] KOG0534 NADH-cytochrome b-5 reductase 187 2e-47
7294666 [HC] KOG0534 NADH-cytochrome b-5 reductase 186 2e-47
CE13277 [HC] KOG0534 NADH-cytochrome b-5 reductase 186 3e-47
Hs7706455 [HC] KOG0534 NADH-cytochrome b-5 reductase 184 1e-46
CE13275 [HC] KOG0534 NADH-cytochrome b-5 reductase 183 2e-46
At1g37130_3 [HC] KOG0534 NADH-cytochrome b-5 reductase 181 1e-45
Hs6552328 [HC] KOG0534 NADH-cytochrome b-5 reductase 179 3e-45
Hs4503327 [HC] KOG0534 NADH-cytochrome b-5 reductase 179 3e-45
YKL150w [HC] KOG0534 NADH-cytochrome b-5 reductase 160 1e-39
At5g20080 [HC] KOG0534 NADH-cytochrome b-5 reductase 148 7e-36
Hs7705899_2 [HC] KOG0534 NADH-cytochrome b-5 reductase 101 1e-21
7302484_2 [HC] KOG0534 NADH-cytochrome b-5 reductase 70 3e-12
SPAC17H9.12c [HC] KOG0534 NADH-cytochrome b-5 reductase 65 1e-10
CE20292_2 [HC] KOG0534 NADH-cytochrome b-5 reductase 61 2e-09
7293557 [HC] KOG0534 NADH-cytochrome b-5 reductase 57 2e-08
At5g66190 [C] KOG1158 NADP/FAD dependent oxidoreductase 52 1e-06
Hs20474889 [HC] KOG0534 NADH-cytochrome b-5 reductase 50 3e-06
>YIL043c [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 322
Score = 332 bits (851), Expect = 4e-91
Identities = 166/276 (60%), Positives = 208/276 (75%), Gaps = 7/276 (2%)
Query: 13 VLLCTIIAVVLEYQ---SKKDKPVLDKEK--LQEFPLVAKTVLTHNTAIYRFGLPKSTQV 67
V++ I+ V L ++ K KPVLD ++ Q FPLV KT+LTHNT++Y+FGLP + V
Sbjct: 47 VVVIVIVVVPLLFKFIIGPKTKPVLDPKRNDFQSFPLVEKTILTHNTSMYKFGLPHADDV 106
Query: 68 LGLPIGQHISVQANINGKDILRSYTPTSLDSDAVGHFELLIKSYEKGNISKHFAQLNIGD 127
LGLPIGQHI ++ANINGKDI RSYTPTSLD D G+FELL+KSY GN+SK +L IGD
Sbjct: 107 LGLPIGQHIVIKANINGKDITRSYTPTSLDGDTKGNFELLVKSYPTGNVSKMIGELKIGD 166
Query: 128 KIKVRGPKGFYHYQPNMNEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEE 187
I+++GP+G YHY+ N +GMIAGGTGIAPMYQIMK+I + D TKVSLV+GN EE
Sbjct: 167 SIQIKGPRGNYHYERNCRSHLGMIAGGTGIAPMYQIMKAIAMDPHDTTKVSLVFGNVHEE 226
Query: 188 DILLKKELDAFVERKPDQFKVYYLLDKAP-EAWTGGVGYITVDTMKERLPAPA-EGVQLL 245
DILLKKEL+A V KP QFK+ Y LD E WTGGVGYIT D +KE LPA + VQ+L
Sbjct: 227 DILLKKELEALVAMKPSQFKIVYYLDSPDREDWTGGVGYITKDVIKEHLPAATMDNVQIL 286
Query: 246 VCGPPPMVSSIKRNAVTLGYEKAKPISKMGDQIFVF 281
+CGPP MV+S++R+ V LG+ ++KP+SKM DQ+FVF
Sbjct: 287 ICGPPAMVASVRRSTVDLGFRRSKPLSKMEDQVFVF 322
>SPCC970.03 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 301
Score = 262 bits (670), Expect = 4e-70
Identities = 123/245 (50%), Positives = 178/245 (72%), Gaps = 2/245 (0%)
Query: 37 EKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYTPTSL 96
+K+Q+F L K VL HNTAIYRF LP++ VLGLPIGQH+ V +++GK+ RSYTP S
Sbjct: 59 DKIQQFELSDKAVLNHNTAIYRFRLPRANDVLGLPIGQHLKVFVDVDGKEYSRSYTPLSS 118
Query: 97 DSDAVGHFELLIKSYEKGNISKHFAQLNIGDKIKVRGPKGFYHYQPNMNEEIGMIAGGTG 156
D+D G+F+LL+KSY G +SK F++L IGD I VRGPKG + ++ + GMIAGGTG
Sbjct: 119 DADK-GYFDLLVKSYPNGKVSKKFSELKIGDTIGVRGPKGNWKHRTGLARHFGMIAGGTG 177
Query: 157 IAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAFVERKPDQFKVYYLLDKAP 216
I PM QI++++ +N D T+++L+Y N +E DI+L+ E+DA ++ P +F V+Y+L+ P
Sbjct: 178 ITPMLQIIRAVLSNFEDPTEITLLYANVSEGDIVLRDEIDALAKKDP-RFTVHYVLNNPP 236
Query: 217 EAWTGGVGYITVDTMKERLPAPAEGVQLLVCGPPPMVSSIKRNAVTLGYEKAKPISKMGD 276
E W G VG++T + +K PAP+ ++L+CGP PMV+S++ V LGYEK++ ISK+ D
Sbjct: 237 ENWKGSVGFVTQELIKAHFPAPSPETKVLICGPTPMVNSLREATVALGYEKSRAISKLED 296
Query: 277 QIFVF 281
Q+FVF
Sbjct: 297 QVFVF 301
>At5g17770 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 281
Score = 251 bits (641), Expect = 8e-67
Identities = 119/240 (49%), Positives = 166/240 (68%), Gaps = 2/240 (0%)
Query: 27 SKKDKPVLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANIN-GK 85
SKK + LD E +EF LV + L+HN A + F LP ST VLGLPIGQHIS + G+
Sbjct: 35 SKKRRVCLDPENFKEFKLVKRHQLSHNVAKFVFELPTSTSVLGLPIGQHISCRGKDGQGE 94
Query: 86 DILRSYTPTSLDSDAVGHFELLIKSYEKGNISKHFAQLNIGDKIKVRGPKGFYHYQPNMN 145
D+++ YTPT+LDSD VG FEL+IK Y +G +S HF ++ +GD + V+GPKG + YQP
Sbjct: 95 DVIKPYTPTTLDSD-VGRFELVIKMYPQGRMSHHFREMRVGDHLAVKGPKGRFKYQPGQF 153
Query: 146 EEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAFVERKPDQ 205
GM+AGG+GI PM+Q+ ++I N +DKTKV L+Y N T +DILLK+EL+ P+Q
Sbjct: 154 RAFGMLAGGSGITPMFQVARAILENPTDKTKVHLIYANVTYDDILLKEELEGLTTNYPEQ 213
Query: 206 FKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVCGPPPMVSSIKRNAVTLGY 265
FK++Y+L++ PE W GGVG+++ + ++ PAPA +Q+L CGPPPM ++ N LGY
Sbjct: 214 FKIFYVLNQPPEVWDGGVGFVSKEMIQTHCPAPASDIQILRCGPPPMNKAMAANLEALGY 273
>YML125c [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 312
Score = 201 bits (511), Expect = 1e-51
Identities = 106/264 (40%), Positives = 160/264 (60%), Gaps = 2/264 (0%)
Query: 18 IIAVVLEYQSKKDKPVLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHIS 77
+I V Y + K + L ++ L +T+++ NTA+YRF L + L +P G H++
Sbjct: 51 MIIFVRAYSAYKRRRSLYPDRWTSLELEDQTIISKNTALYRFKLKTRLESLDIPAGHHVA 110
Query: 78 VQANINGKDILRSYTPTSLDSDAVGHFELLIKSYEKGNISKHFAQLNIGDKIKVRGPKGF 137
V+ I+GK +R Y P S ++ G+ +L++K+Y G +SK+FA LN GD + +GP G
Sbjct: 111 VRVPIDGKQEVRYYNPISSKLES-GYLDLVVKAYVDGKVSKYFAGLNSGDTVDFKGPIGT 169
Query: 138 YHYQPNMNEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDA 197
+Y+PN ++ +G++AGG+GI P+ QI+ I D TKVSL+Y N+TE DILLK ELD
Sbjct: 170 LNYEPNSSKHLGIVAGGSGITPVLQILNEIITVPEDLTKVSLLYANETENDILLKDELDE 229
Query: 198 FVERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVCGPPPMVSSIK 257
E+ P F+V+Y++ + WTG VGYIT D M LP +E +LL+CGP M +
Sbjct: 230 MAEKYP-HFQVHYVVHYPSDRWTGDVGYITKDQMNRYLPEYSEDNRLLICGPDGMNNLAL 288
Query: 258 RNAVTLGYEKAKPISKMGDQIFVF 281
+ A LG++ S DQ+FVF
Sbjct: 289 QYAKELGWKVNSTRSSGDDQVFVF 312
>Hs7706443 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 276
Score = 197 bits (502), Expect = 1e-50
Identities = 105/267 (39%), Positives = 157/267 (58%), Gaps = 29/267 (10%)
Query: 27 SKKDKPVL--DKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANING 84
S++ +P+ D E PL+ K ++HNT +RFGLP VLGLP+G ++ + A I+
Sbjct: 3 SRRREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDN 62
Query: 85 KDILRSYTPTSLDSDAVGHFELLIKSY---------EKGNISKHFAQLNIGDKIKVRGPK 135
+ ++R+YTP S D D G +L+IK Y E G ++++ + IG+ I RGP+
Sbjct: 63 ELVVRAYTPVSSDDDR-GFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPR 121
Query: 136 G--FYHYQPNMN--------------EEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSL 179
G FYH N+ + +GMIAGGTGI PM Q+++ I + SD+T++SL
Sbjct: 122 GRLFYHGPRNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMSL 181
Query: 180 VYGNQTEEDILLKKELDAFVERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPA 239
++ NQTEEDIL++KEL+ PDQF ++Y LD+ P W G++T D +KE LP PA
Sbjct: 182 IFANQTEEDILVRKELEEIARTHPDQFDLWYTLDRPPIGWKYSSGFVTADMIKEHLPPPA 241
Query: 240 EGVQLLVCGPPPMVSSIKR-NAVTLGY 265
+ +LVCGPP ++ + N LGY
Sbjct: 242 KSTLILVCGPPTLIQTAAHPNLEKLGY 268
>YML087c [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 312
Score = 191 bits (484), Expect = 1e-48
Identities = 96/248 (38%), Positives = 151/248 (60%), Gaps = 2/248 (0%)
Query: 34 LDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYTP 93
L + K PL KT ++ NT++Y F L + L +P+G H++V+ ING+ ++R YTP
Sbjct: 67 LYRNKWVALPLSKKTRISRNTSLYCFKLKYPFERLHIPMGYHLAVRVTINGERLVRYYTP 126
Query: 94 TSLDSDAVGHFELLIKSYEKGNISKHFAQLNIGDKIKVRGPKGFYHYQPNMNEEIGMIAG 153
++ + GH EL++K+Y+ G +SK+F +L I ++ +GP G Y + E+G+IAG
Sbjct: 127 VNVPNTE-GHLELVVKTYKHGVVSKYFDKLKIRQYVEFKGPLGELEYDQDTATELGIIAG 185
Query: 154 GTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAFVERKPDQFKVYYLLD 213
G+GI P+ Q+++ I + D T +SL+Y N+TE+DIL+K +LD + P FKV+Y++
Sbjct: 186 GSGITPVLQVLQEIIPSPEDLTHISLIYANETEDDILMKSQLDHMAKEYP-HFKVHYVIH 244
Query: 214 KAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVCGPPPMVSSIKRNAVTLGYEKAKPISK 273
K W G VGY+T++ MK LP AE +LL+CGPP M + A LG+
Sbjct: 245 KPNGKWNGDVGYVTLEEMKRYLPKQAEDHRLLICGPPKMNEMVLNYAKELGWSNGFHKGN 304
Query: 274 MGDQIFVF 281
D++FVF
Sbjct: 305 GTDKVFVF 312
>At1g77760_3 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 264
Score = 187 bits (475), Expect = 1e-47
Identities = 97/243 (39%), Positives = 152/243 (61%), Gaps = 22/243 (9%)
Query: 44 LVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYTPTSLDSDAVGH 103
L+ KT ++H+ +RF LP Q LGLP+G+H+ V ANIN K LR+YTPTS DAVGH
Sbjct: 14 LIEKTSISHDVRKFRFALPSEDQQLGLPVGKHVFVCANINDKLCLRAYTPTSA-IDAVGH 72
Query: 104 FELLIKSYEK---------GNISKHFAQLNIGDKIKVRGPKGFYHYQ----------PNM 144
+L++K Y K G +S+H L IG I ++GP G Y+ P
Sbjct: 73 IDLVVKVYFKDVHPRFPNGGLMSQHLDSLPIGSMIDIKGPLGHIEYKGKGNFLVSGKPKF 132
Query: 145 NEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAFVERKPD 204
+++ M+AGGTGI P+YQI++SI ++ D+T++ +VY N+TE+DIL+++EL+ + + +
Sbjct: 133 AKKLAMLAGGTGITPIYQIIQSILSDPEDETEMYVVYANRTEDDILVREELEGWASKHKE 192
Query: 205 QFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQL-LVCGPPPMVS-SIKRNAVT 262
+ K++Y+++ A E W+ G+IT ++E +P EG L L CGPPPM+ +++ N
Sbjct: 193 RLKIWYVVEIAKEGWSYSTGFITEAVLREHIPEGLEGESLALACGPPPMIQFALQPNLEK 252
Query: 263 LGY 265
+GY
Sbjct: 253 MGY 255
>Hs14735899 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 305
Score = 187 bits (474), Expect = 2e-47
Identities = 99/261 (37%), Positives = 155/261 (58%), Gaps = 27/261 (10%)
Query: 33 VLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYT 92
+LD + L+ KT ++HNT +RF LP + LGLP+G+HI + I+G ++R YT
Sbjct: 40 LLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYT 99
Query: 93 PTSLDSDAVGHFELLIKSY---------EKGNISKHFAQLNIGDKIKVRGP--------K 135
P + D D G+ +L+IK Y E G +S++ L +GD ++ RGP K
Sbjct: 100 PVTSDEDQ-GYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGK 158
Query: 136 GFYHYQPNMN--------EEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEE 187
G ++ QPN +++GMIAGGTGI PM Q++++I D T+ L++ NQTE+
Sbjct: 159 GHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEK 218
Query: 188 DILLKKELDAFVERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVC 247
DI+L+++L+ R P++FK+++ LD P+ W G++T D ++E LPAP + V +L+C
Sbjct: 219 DIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLC 278
Query: 248 GPPPMVS-SIKRNAVTLGYEK 267
GPPPMV + N LGY +
Sbjct: 279 GPPPMVQLACHPNLDKLGYSQ 299
>7294666 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 313
Score = 186 bits (473), Expect = 2e-47
Identities = 103/262 (39%), Positives = 151/262 (57%), Gaps = 28/262 (10%)
Query: 31 KPVLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRS 90
+ ++D PL+ K L+H+T +RFGLP VLGLP+GQHI + A I+ + I+R
Sbjct: 45 RTLVDPNDKYLLPLIEKENLSHDTRRFRFGLPSKQHVLGLPVGQHIHLIATIDNELIIRP 104
Query: 91 YTPTSLDSDAVGHFELLIKSYEK---------GNISKHFAQLNIGDKIKVRGPKGFYHYQ 141
YTP S D D VG+ +L++K Y K G +++H QL +GDKI RGP G Y
Sbjct: 105 YTPISSDED-VGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYL 163
Query: 142 PNMN----------------EEIGMIAGGTGIAPMYQIMKSIFA-NDSDKTKVSLVYGNQ 184
N + + MIAGGTGI PM Q+ + + +D DKT+++L++ NQ
Sbjct: 164 GNGTFSIKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQ 223
Query: 185 TEEDILLKKELDAFVERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQL 244
+E+DILL+ ELD ++ PDQFK++Y +DKA E W VG+I + + L + +
Sbjct: 224 SEKDILLRAELDELAQKHPDQFKIWYTVDKANEGWQYSVGFINEEMIAAHLLPAKDDTIV 283
Query: 245 LVCGPPPMVSSIKRNAV-TLGY 265
L+CGPPPM++ A+ LGY
Sbjct: 284 LLCGPPPMINFACNPALDKLGY 305
>CE13277 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 309
Score = 186 bits (472), Expect = 3e-47
Identities = 96/254 (37%), Positives = 148/254 (57%), Gaps = 26/254 (10%)
Query: 26 QSKKDKPVLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGK 85
+ K + ++D PL+ K ++H+T +RFGLP +LGLPIGQH+ + ANI+GK
Sbjct: 37 KKSKKRTLVDDSVKYPLPLIEKFEISHDTRKFRFGLPSKDHILGLPIGQHVYLTANIDGK 96
Query: 86 DILRSYTPTSLDSDAVGHFELLIKSY---------EKGNISKHFAQLNIGDKIKVRGPKG 136
I+R YTP S D D +G +L++K Y E G +S+H L IGD I RGP+G
Sbjct: 97 IIVRPYTPVSSDED-LGFVDLMVKVYFKNTNEKFPEGGKMSQHLESLKIGDTINFRGPQG 155
Query: 137 FYHYQPN----------------MNEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLV 180
Y+ + + + + MIAGGTGI PM Q++ +I + +D T++ L+
Sbjct: 156 NIVYKGHGLFSIKADKKAEPKNRVFKHLSMIAGGTGITPMLQVIAAILRDPTDTTQIRLL 215
Query: 181 YGNQTEEDILLKKELDAFVERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAE 240
+ NQTE+DIL ++ELD + P +F+V+Y +D+ P W+ G+I +KE L P +
Sbjct: 216 FANQTEDDILCRQELDDLAKEHPTRFRVWYTVDRPPVMWSYSSGFINDSMIKENLFPPGD 275
Query: 241 GVQLLVCGPPPMVS 254
+L+CGPPPM++
Sbjct: 276 DSAVLLCGPPPMIN 289
>Hs7706455 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 305
Score = 184 bits (467), Expect = 1e-46
Identities = 98/261 (37%), Positives = 154/261 (58%), Gaps = 27/261 (10%)
Query: 33 VLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYT 92
+LD + L+ KT ++HNT +RF LP + LGLP+G+HI + I+G ++R YT
Sbjct: 40 LLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGNLVIRPYT 99
Query: 93 PTSLDSDAVGHFELLIKSY---------EKGNISKHFAQLNIGDKIKVRGP--------K 135
P + D D G+ +L+IK Y E G +S++ L +G ++ RGP K
Sbjct: 100 PVTSDEDQ-GYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGHVVEFRGPSGLLTYTGK 158
Query: 136 GFYHYQPNMN--------EEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEE 187
G ++ QPN +++GMIAGGTGI PM Q++++I D T+ L++ NQTE+
Sbjct: 159 GHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEK 218
Query: 188 DILLKKELDAFVERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVC 247
DI+L+++L+ R P++FK+++ LD P+ W G++T D ++E LPAP + V +L+C
Sbjct: 219 DIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLC 278
Query: 248 GPPPMVS-SIKRNAVTLGYEK 267
GPPPMV + N LGY +
Sbjct: 279 GPPPMVQLACHPNLDKLGYSQ 299
>CE13275 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 303
Score = 183 bits (465), Expect = 2e-46
Identities = 99/253 (39%), Positives = 146/253 (57%), Gaps = 27/253 (10%)
Query: 28 KKDKPVLDKEKLQEF-PLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKD 86
KK K L+ + ++ PL+ K ++HNT +RFGLP +LGLPIG H+ + ANI GK
Sbjct: 32 KKSKRTLEDDSVKYLLPLIEKFEISHNTRKFRFGLPSKDHILGLPIGHHVYLSANIGGKL 91
Query: 87 ILRSYTPTSLDSDAVGHFELLIKSYEK---------GNISKHFAQLNIGDKIKVRGPKGF 137
I+RSYTP S D D +G+ +L++K Y K G +S+H L IGD + RGP G
Sbjct: 92 IVRSYTPVSCDLD-LGYVDLMVKVYFKNTHERFPDGGKMSQHLESLKIGDTVSFRGPHGS 150
Query: 138 YHYQPN----------------MNEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVY 181
Y+ + + + MIAGGTGI PM Q++ +I + D T++ L++
Sbjct: 151 IIYKGSGLFTVRMDKKAEPKNRFFKHLSMIAGGTGITPMLQVIAAILRDPIDATQIRLLF 210
Query: 182 GNQTEEDILLKKELDAFVERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEG 241
NQTE+DIL +KELD E+ P +F+V+Y + KA + W G+I + +KE L E
Sbjct: 211 ANQTEDDILCRKELDELAEKHPTRFRVWYTVSKASKDWRYSTGHINEEMIKEHLFPSNEE 270
Query: 242 VQLLVCGPPPMVS 254
+L+CGPP M++
Sbjct: 271 SAVLLCGPPAMIN 283
>At1g37130_3 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 264
Score = 181 bits (459), Expect = 1e-45
Identities = 93/230 (40%), Positives = 144/230 (62%), Gaps = 21/230 (9%)
Query: 44 LVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYTPTSLDSDAVGH 103
LV KT ++H+ +RF LP VLGLP+G+HI + A IN K LR+YTP+S D VG+
Sbjct: 14 LVEKTSISHDVRKFRFALPVEDMVLGLPVGKHIFLCATINDKLCLRAYTPSST-VDVVGY 72
Query: 104 FELLIKSY---------EKGNISKHFAQLNIGDKIKVRGPKGFYHY----------QPNM 144
FEL++K Y G +S++ L IG ++++GP G Y +P
Sbjct: 73 FELVVKIYFGGVHPRFPNGGLMSQYLDSLPIGSTLEIKGPLGHVEYLGKGSFTVHGKPKF 132
Query: 145 NEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAFVERKPD 204
+++ M+AGGTGI P+YQI+++I + D+T++ ++Y N+TEEDILL++ELD + E+ PD
Sbjct: 133 ADKLAMLAGGTGITPVYQIIQAILKDPEDETEMYVIYANRTEEDILLREELDGWAEQYPD 192
Query: 205 QFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQL-LVCGPPPMV 253
+ KV+Y+++ A E W G+I+ M+E +P +G L + CGPPPM+
Sbjct: 193 RLKVWYVVESAKEGWAYSTGFISEAIMREHIPDGLDGSALAMACGPPPMI 242
>Hs6552328 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 278
Score = 179 bits (455), Expect = 3e-45
Identities = 93/235 (39%), Positives = 140/235 (59%), Gaps = 26/235 (11%)
Query: 44 LVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYTPTSLDSDAVGH 103
L+ + +++H+T +RF LP +LGLP+GQHI + A I+G ++R YTP S D D G
Sbjct: 24 LIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDK-GF 82
Query: 104 FELLIKSYEK---------GNISKHFAQLNIGDKIKVRGPKGFYHYQ--------PNMN- 145
+L+IK Y K G +S++ + IGD I+ RGP G YQ P+
Sbjct: 83 VDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKS 142
Query: 146 -------EEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAF 198
+ +GMIAGGTGI PM Q++++I + D T L++ NQTE+DILL+ EL+
Sbjct: 143 NPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEEL 202
Query: 199 VERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVCGPPPMV 253
+ +FK++Y LD+APEAW G G++ + +++ LP P E +L+CGPPPM+
Sbjct: 203 RNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMI 257
>Hs4503327 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 301
Score = 179 bits (455), Expect = 3e-45
Identities = 93/235 (39%), Positives = 140/235 (59%), Gaps = 26/235 (11%)
Query: 44 LVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYTPTSLDSDAVGH 103
L+ + +++H+T +RF LP +LGLP+GQHI + A I+G ++R YTP S D D G
Sbjct: 47 LIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDK-GF 105
Query: 104 FELLIKSYEK---------GNISKHFAQLNIGDKIKVRGPKGFYHYQ--------PNMN- 145
+L+IK Y K G +S++ + IGD I+ RGP G YQ P+
Sbjct: 106 VDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKS 165
Query: 146 -------EEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAF 198
+ +GMIAGGTGI PM Q++++I + D T L++ NQTE+DILL+ EL+
Sbjct: 166 NPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEEL 225
Query: 199 VERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVCGPPPMV 253
+ +FK++Y LD+APEAW G G++ + +++ LP P E +L+CGPPPM+
Sbjct: 226 RNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMI 280
>YKL150w [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 302
Score = 160 bits (406), Expect = 1e-39
Identities = 83/232 (35%), Positives = 134/232 (56%), Gaps = 4/232 (1%)
Query: 27 SKKDKPVLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQ-ANINGK 85
++ +K +K + P+ +H+T + F LP +GL + + + G
Sbjct: 41 NESNKVFKGDDKWIDLPISKIEEESHDTRRFTFKLPTEDSEMGLVLASALFAKFVTPKGS 100
Query: 86 DILRSYTPTSLDSDAVGHFELLIKSYEKGNISKHFAQLNIGDKIKVRGPKGFYHYQPNMN 145
+++R YTP S D GHF+L++K YE G ++ H L D + +GP + +QPN
Sbjct: 101 NVVRPYTPVS-DLSQKGHFQLVVKHYEGGKMTSHLFGLKPNDTVSFKGPIMKWKWQPNQF 159
Query: 146 EEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAFVERKPDQ 205
+ I ++ GTGI P+YQ+ I N +DKTKV+L+YGN+T +DILL+KELDA E+ PD+
Sbjct: 160 KSITLLGAGTGINPLYQLAHHIVENPNDKTKVNLLYGNKTPQDILLRKELDALKEKYPDK 219
Query: 206 FKVYYLLD--KAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVCGPPPMVSS 255
F V Y +D + + + G + +I+ D ++E +P P E L VCGPPP +++
Sbjct: 220 FNVTYFVDDKQDDQDFDGEISFISKDFIQEHVPGPKESTHLFVCGPPPFMNA 271
>At5g20080 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 308
Score = 148 bits (374), Expect = 7e-36
Identities = 88/232 (37%), Positives = 128/232 (54%), Gaps = 29/232 (12%)
Query: 31 KPVLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQA----NINGKD 86
K L+ +K EF L ++HNT ++RF S + LGL + + +A N GK
Sbjct: 70 KTALNPDKWLEFKLQDTARVSHNTQLFRFSFDPSAE-LGLHVASCLLTRAPLGYNAEGKT 128
Query: 87 --ILRSYTPTSLDSDAVGHFELLIKSYEKGNISKHFAQLNIGDKIKVRGPKGFYHYQPNM 144
++R YTP S D +A G+F+LLIK Y G +S+HFA L GD ++
Sbjct: 129 KYVIRPYTPIS-DPEAKGYFDLLIKVYPDGKMSQHFASLKPGDVLE-------------- 173
Query: 145 NEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAFVERKPD 204
IAGG+GI PM Q++ +I N D T++SL+Y N + +DILLK++LD P+
Sbjct: 174 ------IAGGSGITPMLQVIDAIVKNPEDNTQISLLYANVSPDDILLKQKLDVLQANHPN 227
Query: 205 QFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVCGPPPMVSSI 256
K++Y +D + W GGVGYI+ D + LP P + +LVCGPP M+ I
Sbjct: 228 -LKIFYTVDNPTKNWKGGVGYISKDMALKGLPLPTDDTLILVCGPPGMMEHI 278
>Hs7705899_2 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 243
Score = 101 bits (252), Expect = 1e-21
Identities = 72/240 (30%), Positives = 119/240 (49%), Gaps = 22/240 (9%)
Query: 44 LVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYTPTSLDSDAVGH 103
L++K +TH+T ++ LP ST L +PIGQH+ ++ I G +I++ YTP S +
Sbjct: 2 LISKEDVTHDTRLFCLMLPPSTH-LQVPIGQHVYLKLPITGTEIVKPYTPVS--GSLLSE 58
Query: 104 FE-----------LLIKSYEKGNISKHFAQLNIGDKIKVRGPKGFYHYQPNMN-EEIGMI 151
F+ LIK Y G + +L IGD + V P+G + E++ ++
Sbjct: 59 FKEPVLPNNKYIYFLIKIYPTGLFTPELDRLQIGDFVSVSSPEGNFKISKFQELEDLFLL 118
Query: 152 AGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELD--AFVERKPDQFKVY 209
A GTG PM +I+ + KV L++ N+TE+DI+ + +L+ AF +++ D V
Sbjct: 119 AAGTGFTPMVKILNYALTDIPSLRKVKLMFFNKTEDDIIWRSQLEKLAFKDKRLD---VE 175
Query: 210 YLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQLLV--CGPPPMVSSIKRNAVTLGYEK 267
++L W G G+I+ + E L + ++LV CGP P R L + K
Sbjct: 176 FVLSAPISEWNGKQGHISPALLSEFLKRNLDKSKVLVCICGPVPFTEQGVRLLHDLNFSK 235
>7302484_2 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 248
Score = 70.5 bits (171), Expect = 3e-12
Identities = 39/136 (28%), Positives = 71/136 (51%), Gaps = 10/136 (7%)
Query: 70 LPIGQHISVQANINGKDILRSYTPT--------SLDSDAVGHFELLIKSYEKGNISKHFA 121
LP G H+ ++ + G+ I RSYTP ++ S LIK Y G +S H
Sbjct: 36 LPAGYHVDIEVPLEGRVIQRSYTPVDHTYLRLENIRSSRSECLHFLIKRYPNGPVSSHLQ 95
Query: 122 QLNIGDKIKVRGPKGFYHYQP-NMNEEIGMIAGGTGIAPMYQIMKSIFANDSDKTK-VSL 179
+L G ++ P+G + + I ++A G+G+ P+ +++ I ++++ + + L
Sbjct: 96 KLETGSRVHWSAPRGSFQLSDLTAHRNILLLAAGSGLTPILSLIQPILKRNTNRIESLQL 155
Query: 180 VYGNQTEEDILLKKEL 195
+Y N+T EDI LK++L
Sbjct: 156 LYFNKTNEDIWLKEKL 171
>SPAC17H9.12c [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 266
Score = 64.7 bits (156), Expect = 1e-10
Identities = 49/172 (28%), Positives = 81/172 (46%), Gaps = 10/172 (5%)
Query: 25 YQSKKDKPVLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANING 84
Y++ P L+ E F + T LT + +++ +P+S + V
Sbjct: 28 YKNSNKPPGLNPEIYAPFTVNKITELTSDASLFSL-VPQSPSEHLTTLEPIAKVTIRDPS 86
Query: 85 KDILRSYTPTSLDSDAVGHFELLIKSYEKGNISKHFAQLNIGDKIKVRGPKGFYHYQPNM 144
+ R YTP LD++ + F I+ YE+G +S + GD I++RGP
Sbjct: 87 MQVQRPYTPLYLDANELKFF---IRKYEEGPVSSYIHSKKEGDTIELRGPFKTTKLDCTK 143
Query: 145 NEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELD 196
I I GTGIAP+YQ+ +S+ K+ V +VY ++ + LLK+EL+
Sbjct: 144 YPRIVAIVAGTGIAPIYQLAQSV------KSPVDIVYCSRPGQPPLLKEELE 189
>CE20292_2 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 262
Score = 60.8 bits (146), Expect = 2e-09
Identities = 49/158 (31%), Positives = 74/158 (46%), Gaps = 22/158 (13%)
Query: 50 LTHNTAIYRFGLPKSTQVLGLPIGQHISVQAN-------------INGKDIL-RSYTPTS 95
L H+T I+ LP+ T +PIG H+S++ I G +L R YTP S
Sbjct: 8 LNHDTLIFSLQLPEHT-TYRIPIGHHVSIKIRKGSMGKFSWKFFLIFGYSVLYRPYTPIS 66
Query: 96 LDSDAVGHFELLIKSYEKGNISKHFAQLNIGDKIKVRGPKG---FYHYQPNMNEEIGMIA 152
+ +IK Y G + L IG ++++ P G F + N E I ++A
Sbjct: 67 NPDPQ--KIDFMIKIYSNGICTPSLENLKIGGELEISDPIGERNFAEWTENAQELI-LLA 123
Query: 153 GGTGIAPMYQIM-KSIFANDSDKTKVSLVYGNQTEEDI 189
G+GI PM IM K I ++ +KV + N+TE D+
Sbjct: 124 AGSGITPMIDIMEKRIQKTENSNSKVYFLMFNKTENDL 161
>7293557 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 315
Score = 57.4 bits (137), Expect = 2e-08
Identities = 33/111 (29%), Positives = 59/111 (52%), Gaps = 5/111 (4%)
Query: 67 VLGLPIGQHISVQANINGKDILRSYTPTSLDSDAVGHFELLIKSYEKGNISKHFAQLNIG 126
VL +P G H+ ++ +LR Y+P D A F +L+K +G +S+H +
Sbjct: 90 VLDIPPGHHVMLRVG----SLLRPYSPYWSDFVAK-EFRILVKLQPEGPMSRHLQAVQPD 144
Query: 127 DKIKVRGPKGFYHYQPNMNEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKV 177
D ++ RGP G Y ++P + I +IA G IAP +++ + N+ D +++
Sbjct: 145 DLLEFRGPIGQYVHEPQPAKCIYIIAQGVAIAPTLPLVRQVLDNEEDMSRL 195
>At5g66190 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 360
Score = 51.6 bits (122), Expect = 1e-06
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 113 KGNISKHFAQLNIGDKIKVRGPKGFYHYQP-NMNEEIGMIAGGTGIAPMYQIMKSIFAND 171
KG S L GD+ K+ GP G P + N I M+ GTGIAP + +F +
Sbjct: 175 KGVCSNFLCDLKPGDEAKITGPVGKEMLMPKDPNATIIMLGTGTGIAPFRSFLWKMFFEE 234
Query: 172 SDKTKVS----LVYGNQTEEDILLKKELDAFVERKPDQFKVYYLLDKAPEAWTGGVGYI 226
+ K + L G T +L K+E + E+ PD F++ + + + G YI
Sbjct: 235 HEDYKFNGLAWLFLGVPTSSSLLYKEEFEKMKEKNPDNFRLDFAVSREQTNEKGEKMYI 293
>Hs20474889 [HC] KOG0534 NADH-cytochrome b-5 reductase
Length = 163
Score = 50.4 bits (119), Expect = 3e-06
Identities = 31/76 (40%), Positives = 48/76 (62%), Gaps = 2/76 (2%)
Query: 34 LDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYTP 93
L+ E F ++A LT +T RF LP ++Q LGL GQH+ ++ ++ +I R+YTP
Sbjct: 72 LNPETFVAFCIIAMDRLTKDTYRVRFALPGNSQ-LGLRPGQHLILRGIVDDLEIQRAYTP 130
Query: 94 TSLDSDAVGHFELLIK 109
S ++A G+FE+LIK
Sbjct: 131 IS-PANAEGYFEVLIK 145
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.138 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,595,141
Number of Sequences: 60738
Number of extensions: 779927
Number of successful extensions: 1881
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1817
Number of HSP's gapped (non-prelim): 25
length of query: 281
length of database: 30,389,216
effective HSP length: 105
effective length of query: 176
effective length of database: 24,011,726
effective search space: 4226063776
effective search space used: 4226063776
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)