ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7383 good D KOG2011 Cell cycle control, cell division, chromosome partitioning Sister chromatid cohesion complex Cohesin, subunit STAG/IRR1/SCC3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7383 2575720 2572418 -1101
(1101 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL026c [D] KOG2011 Sister chromatid cohesion complex Cohesin su... 561 e-159
SPAC17H9.20_1 [D] KOG2011 Sister chromatid cohesion complex Cohe... 130 1e-29
Hs5032063 [D] KOG2011 Sister chromatid cohesion complex Cohesin ... 103 1e-21
Hs22055161 [D] KOG2011 Sister chromatid cohesion complex Cohesin... 92 3e-18
7297197 [D] KOG2011 Sister chromatid cohesion complex Cohesin su... 91 8e-18
Hs5730069 [D] KOG2011 Sister chromatid cohesion complex Cohesin ... 90 2e-17
Hs6912686 [D] KOG2011 Sister chromatid cohesion complex Cohesin ... 77 1e-13
ECU04g0870 [D] KOG2011 Sister chromatid cohesion complex Cohesin... 68 7e-11
At2g47980 [D] KOG2011 Sister chromatid cohesion complex Cohesin ... 67 1e-10
SPCC4E9.01c [D] KOG2011 Sister chromatid cohesion complex Cohesi... 66 3e-10
CE05664 [D] KOG2011 Sister chromatid cohesion complex Cohesin su... 64 1e-09
>YIL026c [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 1150
Score = 561 bits (1446), Expect = e-159
Identities = 372/1136 (32%), Positives = 589/1136 (51%), Gaps = 63/1136 (5%)
Query: 3 VRRSTRIRTKXXXXXXXXXXXXXXXXTIGSIVTDDRINI--ENTDNQKXXXXXXXXXXXX 60
VRRSTRIRTK T V D+I ++ + ++
Sbjct: 4 VRRSTRIRTKSQVIEEDYDDEQN---TSAQHVESDKITAKTQHEEEEEQDTGESEESSSE 60
Query: 61 XXXXXXXXXXYVAPGSRKRPNSGGRRVASNKRTKLKQNEKGRPSNNISSAVS-------- 112
YV + KR S R+ S T K+ +K +P++ SAVS
Sbjct: 61 DDYEDQDDDDYVDTATAKR-KSRKRKPKSASNTSSKRQKK-KPTSAQKSAVSHAPAYHRS 118
Query: 113 RKEQEAYISLQNEFKPTELFEILSSSDDFSCEELASDWLDSYIDNRNVSLANLINFLLDC 172
+K+Q+ Y+ + +F+PTELF+ILS+S+D S EEL +WL++Y +NR+ L IN LL+C
Sbjct: 119 KKDQDQYLEIAKDFQPTELFDILSTSEDVSIEELLREWLETYSENRDKFLQEFINLLLNC 178
Query: 173 SGCFTHIGEHDVANNDSSNETIGEIQIMFHEQKKHEFHLLLSATHKKA---KFRPLNDNF 229
G + +HDV +N+SSNETIGEIQ++F QK HEF+LL+S +KK K PL NF
Sbjct: 179 CGSVARVEDHDVHSNESSNETIGEIQLLFQRQKLHEFYLLISKENKKRKNFKMGPLYQNF 238
Query: 230 NIFMTTLMDLAIEKEMIYVENEKEESDEIVIETNPLIIDLLTWIPSMSVSKIRCLRYVSA 289
FMT L+++A + +++YVE+++ D+ I T L++DLLTW+ S SV KIRC RY+S
Sbjct: 239 AEFMTKLLEVANDLQLLYVESDE---DDTQIVTGNLVLDLLTWLSSFSVCKIRCFRYIST 295
Query: 290 KAIFCFQDXXXXXXXXXXXXVLFXXXXXXXXXXXXXXXXXXXXXXXESSISDAEATKTVI 349
++ FQD L ES+I++ + +K VI
Sbjct: 296 LTLYLFQDYLTQQAVNLEKNYLAKLSKQLSLEEKKKRPNNKTLEKLESTIAETQGSKVVI 355
Query: 350 ENTIDNIIKLCFVHRFKDVDENIRSLAISYLLDWIENNPDYFFKVTFLKYFGWLLSDSSN 409
++ IDNI+KLCFVHR+KDV + IRS ++ +L WI+N P+YF KVTFLKYFGWLLSD+S
Sbjct: 356 DSIIDNIVKLCFVHRYKDVSDLIRSESMLHLSIWIKNYPEYFLKVTFLKYFGWLLSDNSV 415
Query: 410 SVRLQVIRSLHDLIKFSNKRNKNTVDNAALRQFFERFKDRMLEIAGRDIDIQVRLTSVQV 469
SVRLQV + L LI N +K+T DN+A+RQ FERFK ++LE+A RD+++ VR+ S+QV
Sbjct: 416 SVRLQVTKILPHLI-IQNHNSKST-DNSAIRQVFERFKTKILEVAIRDVNLDVRIHSIQV 473
Query: 470 LSSINGLGYLDDHEIIDIISLIFFDHE---VKVSSSSRDVKFLNEVTKFLANIVSEKTEE 526
L+ + LGYLDD EI+ IIS + FD E K SS ++ KFL+ V KFLA ++ EK +E
Sbjct: 474 LTEASSLGYLDDSEIL-IISSLMFDEEFDPFKTSSFNKRSKFLSTVAKFLARVIKEKFDE 532
Query: 527 FLINNERFKVPVISVTEEQFVKVGVLMRXXXXXXXXXXXXXXXXEGYAKVPPDKIKLLQQ 586
F+ +E V + V+VG+ ++ + KI++L Q
Sbjct: 533 FIKTHEDLPKEVDGLEVGPVVQVGIFIKILNDSLIYHLKDCAEVDSRT-----KIRMLTQ 587
Query: 587 AAEFLSPKFYNLIETISKLLYEEGNF--------DGSTIHADADDFSNDLGDIKLFLPET 638
AAEFLSP ++TI LL + + + ++D +D ++ DI P
Sbjct: 588 AAEFLSPYISTHLKTICNLLISDTESNELIQKLQNSANNNSDDEDVDDEELDITPLFPID 647
Query: 639 DNNVLFYATVLGGLCTGGIQYNKGQDRQAVTQLILPELEDLFKKMNLDSDQIYTQLLNVI 698
N+ + Y V GLC G K Q + +V +++LP DL +++S I LL
Sbjct: 648 RNSTILYLNVFHGLCAGA-NNPKIQTKDSVKEIVLPLFYDLLNAASIESADILCPLLESF 706
Query: 699 QLLNTEEWNSSESKDVIFNINKTITKRFESSPVVLSNANAITKTYKSLIPYLASLQIPEV 758
+ ++W S + + I K F S + S + + I ++ + E+
Sbjct: 707 ITFSLDDWISIGYETELKKITDKTIKAFMDSTIGNSKVDMKYDIFAKFIHHIHHFEKKEL 766
Query: 759 TGYWKSCLINVTLSFKKFMESFDIKSDNS-------ITTLYLQYVNKLVILGKEFAIEIS 811
+ + + + + KKF++ + +NS +LY Y+NKL ILG+++ IE+
Sbjct: 767 QEKFLNQIATLKIHLKKFLQE-KMDPNNSRDDYKDLTCSLYELYINKLTILGRDYPIEVD 825
Query: 812 ETLLDDIVEKFLKPLSELLPKIDSDAISVLDFKLFTSIVTWNLATWRDVI---KNNEEPI 868
E LL + F+ + + D ++FK+ + TWNL WR++I ++ E I
Sbjct: 826 EELLQLFLNNFVSRIPIMFQDFDDSTAQEINFKMLVLLATWNLEKWREIIEKVRDYENSI 885
Query: 869 AVSHTTLNQIRTVLVELLN--LSSKIDSNPEIQH-DKKFHVLHVILSPLLDIIIAFKMFE 925
+ ++ + ++ LN + S +N ++ + F++ + L+DII+A K+FE
Sbjct: 886 SKDLRSVWKPIAAIIGRLNTLVISLAATNETFENINSLFYLKWSACTSLMDIIVAIKIFE 945
Query: 926 LDLSEKDSDWIRALRQEYSVISNEDLTGICHKVFLYLESCLGKFLGITLDRVADEDVNYG 985
L L + W ++ +++ +++ + + K+FLYLES K + + L+RVADED N
Sbjct: 946 LKLPADATTWRYSMSEQFPFYLHDNASKVLLKIFLYLESLFAKQVDVQLERVADEDANLN 1005
Query: 986 AVNLVDVDGDPEKELCIYTXXXXXXXXXXXXNYSDLTTRIGLNQEKLGPLFESVVSETVF 1045
+ + E E ++T + +R+ LN+EKLGPLF+ +V +T+
Sbjct: 1006 DLPETGFFENIETEFLLFTVKLKGLMKLNILD-ERFASRVALNKEKLGPLFKKIVDDTIM 1064
Query: 1046 EDEPKNNAESHPAAKLNQEPVPQQYDEVLEPIEEFTQDETVHSPPHPADPIVSSPI 1101
E+ P+ N ++ AK NQ P++ ++ ET H+ DP + I
Sbjct: 1065 EN-PEPNKKNIQKAKSNQT------QREKAPLQPNSERETDHANTENNDPDIPMTI 1113
>SPAC17H9.20_1 [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 486
Score = 130 bits (326), Expect = 1e-29
Identities = 114/461 (24%), Positives = 192/461 (40%), Gaps = 49/461 (10%)
Query: 81 NSGGRRVASNKRTKLKQNEKGRPSNNISSA-VSRKEQEAYISLQNEFKPTELFEILSS-- 137
NS + + K ++K P N V R + A + E E+F L +
Sbjct: 35 NSSSEENSDDDYEKTISSKKRHPRPNSKGVNVKRSRRNAIVE---EDPQEEIFNNLFAFL 91
Query: 138 -SDDFSCEELASDWLDSYIDNRNVSLANLINFLLDCSGCFTHIGEHDVANNDSSNETIGE 196
++A W Y + +LANLINF+L C GC I DV + DS++ T+ +
Sbjct: 92 LDQKVDTMDIAVSWFADYAKDNQSALANLINFILKCCGCNRAINVFDVQDQDSASATLSQ 151
Query: 197 IQIMFHEQKKHEFHLLLSATHKKAKFR--PLND------NFNIFMTTLMDLAIEKEMI-- 246
IQ+ L L + K R PLN NF +T L+ + + I
Sbjct: 152 IQLSVERVSAFAKILYLYINNFKTSTRDYPLNSKNLKFRNFRKRLTGLLSNFVSQLSIRN 211
Query: 247 YVENEKEESDEIVIETNPLIIDLLTWIPSMSVSKIRCLRYVSAKAIFCFQDXXXXXXXXX 306
Y+ N + + D+++W+ +MS S +R +R+ + +FC
Sbjct: 212 YLYN------------STVFEDIMSWVVAMSSSTMRPIRHTAT--VFCLNIMTFLCEKSK 257
Query: 307 XXXVLFXXXXXXXXXXXXXXXXXXXXXXX-ESSISDAEATKTVIENTIDNIIKLCFVHRF 365
+S+ + + + +++ FVHR+
Sbjct: 258 ELLNEHAIATKQLEKEEKRSRVNRNRINELNNSLGEIVKQQDTLTTYLNDYFDSVFVHRY 317
Query: 366 KDVDENIRSLAISYLLDWIENNPDYFFKVTFLKYFGWLLSDSSNSVRLQVIRSLHDLIKF 425
+DV+ IR + L WI P FF ++L+Y GW+LSD + +VRL V++ L +
Sbjct: 318 RDVEPKIRVDCLQELGVWINTVPSIFFSGSYLRYLGWMLSDINTTVRLTVVKVLRKFFET 377
Query: 426 SNKRNKNTVDNAALRQFFERFKDRMLEIAGRDIDIQVRLTSVQVLSSINGLGYLDDHEII 485
+ LR F RFK+R+LE++ D DI VR+ S+++ +++ G+L++ EI+
Sbjct: 378 DS-------FIGGLRHFSSRFKERILEMSCVDADIGVRVASIRLCNAMRTCGFLENSEIL 430
Query: 486 DIISLIFFDHEVKVSSSSRDVKFLNEVTKFLANIVSEKTEE 526
++ LI D +V E FL +V E E
Sbjct: 431 KVLKLI-LDINPRVQ---------REAVLFLCKVVDESVNE 461
>Hs5032063 [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 1258
Score = 103 bits (257), Expect = 1e-21
Identities = 105/425 (24%), Positives = 182/425 (42%), Gaps = 37/425 (8%)
Query: 75 GSRKRPNSGGRRVASNKRTKLKQNEKGRPSNNISSAVSRKEQEAYISLQNEFKPTELFEI 134
G RKR G R ++NK+ + EK R I A R + E +P LFE+
Sbjct: 33 GKRKRGRPG-RPPSTNKKPRKSPGEKSRIEAGIRGA-GRGRANGHPQQNGEGEPVTLFEV 90
Query: 135 LSSSDDFSCEELASDWLDSYIDNRNVSLANLINFLLDCSGCFTHIGEHDVANNDSSNETI 194
+ + + + DW++SY +R+++L +LINF + CSGC + ++ N + E I
Sbjct: 91 VKLGKS-AMQSVVDDWIESYKQDRDIALLDLINFFIQCSGCRGTV-RIEMFRNMQNAEII 148
Query: 195 GEIQIMFHEQKKHEFHLLLSATHKKAKFRPLNDNFNIFMTTLMDLAIEKEMIYVENEKEE 254
++ F E ++ L + K KFR NF F+ L+ + +IY
Sbjct: 149 RKMTEEFDEDSG-DYPLTMPGPQWK-KFR---SNFCEFIGVLIRQC-QYSIIY------- 195
Query: 255 SDEIVIETNPLIIDLLTWIPSMSVSKIRCLRYVSAKAIFCFQDXXXXXXXXXXXXVLFXX 314
DE +++T +I LLT +S S++R R+ S A +
Sbjct: 196 -DEYMMDT---VISLLT---GLSDSQVRAFRHTSTLAAMKLM--TALVNVALNLSIHQDN 246
Query: 315 XXXXXXXXXXXXXXXXXXXXXESSIS---DAEATKTVIENTIDNIIKLCFVHRFKDVDEN 371
E + + + + IEN +++I K FVHR++D
Sbjct: 247 TQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAE 306
Query: 372 IRSLAISYLLDWIENNPDYFFKVTFLKYFGWLLSDSSNSVRLQVIRSLHDLIKFSNKRNK 431
IR++ I + W++ D F ++LKY GW L D VRL+ +++L L ++N+
Sbjct: 307 IRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSL--YTNREL- 363
Query: 432 NTVDNAALRQFFERFKDRMLEIA-GRDIDIQVRLTSVQVLSSINGLGYLDDHEIIDIISL 490
L F RFKDR++ + ++ D+ V + L L + + ++ L
Sbjct: 364 ----FPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHL 419
Query: 491 IFFDH 495
++ H
Sbjct: 420 VYSAH 424
>Hs22055161 [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 1268
Score = 92.4 bits (228), Expect = 3e-18
Identities = 96/409 (23%), Positives = 175/409 (42%), Gaps = 35/409 (8%)
Query: 91 KRTKLKQNEKGRPSNNISSAVSRKEQEAYISLQNEFKPTELFEILSSSDDFSCEELASDW 150
K+ K EKG+ N S + QN + LFE++ + + + DW
Sbjct: 44 KKGKKGPAEKGKGGNGGGKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKS-AMQSVVDDW 102
Query: 151 LDSYIDNRNVSLANLINFLLDCSGCFTHIGEHDVANNDSSNETIGEIQIMFHEQKKHEFH 210
++SY +R+++L +LINF + CSGC + ++ + ++E I ++ F E ++
Sbjct: 103 IESYKHDRDIALLDLINFFIQCSGC-KGVVTAEMFRHMQNSEIIRKMTEEFDEDSG-DYP 160
Query: 211 LLLSATHKKAKFRPLNDNFNIFMTTLMDLAIEKEMIYVENEKEESDEIVIETNPLIIDLL 270
L ++ K KF+ +F F+ L+ + +IY DE +++T +I LL
Sbjct: 161 LTMAGPQWK-KFK---SSFCEFIGVLVRQC-QYSIIY--------DEYMMDT---VISLL 204
Query: 271 TWIPSMSVSKIRCLRYVSAKAIFCFQDXXXXXXXXXXXXVLFXXXXXXXXXXXXXXXXXX 330
T +S S++R R+ S A +
Sbjct: 205 T---GLSDSQVRAFRHTSTLAAMKLM--TALVNVALNLSINMDNTQRQYEAERNKMIGKR 259
Query: 331 XXXXXESSIS---DAEATKTVIENTIDNIIKLCFVHRFKDVDENIRSLAISYLLDWIENN 387
E + + + + IEN ++ I K FVHR++D IR++ I + W++
Sbjct: 260 ANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMY 319
Query: 388 PDYFFKVTFLKYFGWLLSDSSNSVRLQVIRSLHDLIKFSNKRNKNTVDNAALRQFFERFK 447
D F ++LKY GW + D VRL+ + +L L + NK N+ L F RFK
Sbjct: 320 SDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGL--YYNKEL-----NSKLELFTSRFK 372
Query: 448 DRMLEIA-GRDIDIQVRLTSVQVLSSINGLGYLDDHEIIDIISLIFFDH 495
DR++ + ++ D+ V+ + L + L + ++ L++ H
Sbjct: 373 DRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAH 421
>7297197 [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 1116
Score = 91.3 bits (225), Expect = 8e-18
Identities = 103/447 (23%), Positives = 191/447 (42%), Gaps = 51/447 (11%)
Query: 71 YVAPGSRKRPNSGGRRVASNKRTKLKQNEKGRPSNNISSAVSRKEQEAYISLQNEFKPTE 130
+ AP +RKR R+ + ++ ++++ K V + E I + E E
Sbjct: 53 FFAPIARKRKTPATRKGPTERKERVERPRK--------EPVDKGHHER-IDSEREITTDE 103
Query: 131 --LFEILSSSDDFSCEELASDWLDSYIDNRNVSLANLINFLLDCSGCFTHIGEHDVANND 188
L+ I+ S + + W++ Y NR +L L+ F ++ SGC I E D+
Sbjct: 104 NSLYYIVRHSKN-PIASIVDQWIEQYKANRETALVALMQFFINASGCKGKISE-DIQYPV 161
Query: 189 SSNETIGEIQIMFHEQKKHEFHLLLSATHKKAKFRPLNDNFNIFMTTLMDLAIEKEMIYV 248
I + F E+ E+ L++S T ++R +NF F+ TL+ + +IY
Sbjct: 162 DHTSIIRRMTEEFDEESG-EYPLIMSGT----QWRKFKNNFCDFVQTLVKQC-QYSIIY- 214
Query: 249 ENEKEESDEIVIETNPLIIDLLTWIPSMSVSKIRCLRYVSAKAIFCFQDXXXXXXXXXXX 308
D+ +++ +I LLT +S S++R R+ + A
Sbjct: 215 -------DQFLMDN---VISLLT---GLSDSQVRAFRHTATLAAMKLMTALVDVALLVSN 261
Query: 309 XVLFXXXXXXXXXXXXXXXXXXXXXXXESSI---SDAEATKTVIENTIDNIIKLCFVHRF 365
F +S + S+ E I++ + + K FVHR+
Sbjct: 262 N--FDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRY 319
Query: 366 KDVDENIRSLAISYLLDWIENNPDYFFKVTFLKYFGWLLSDSSNSVRLQVIRSLHDLIKF 425
+D +IR++ ++ + W+EN P F ++LKY GW L D VRL+ ++SL L +
Sbjct: 320 RDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEK 379
Query: 426 SNKRNKNTVDNAALRQFFERFKDRMLEIAGRDIDIQVRLTSVQVLSSINGL--GYLDDHE 483
+ K L F +FKDR++ + D + +V + +V+++ SI + L D +
Sbjct: 380 DELKGK-------LELFTSKFKDRIVAMT-LDKEFEVSVHAVKLVISILKIHPEILADKD 431
Query: 484 IIDIISLIFFDHEVKVSSSSRDVKFLN 510
+ L++ H +++ +FLN
Sbjct: 432 CEIVYELVYSSHRGVAQAAA---EFLN 455
>Hs5730069 [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 1162
Score = 90.1 bits (222), Expect = 2e-17
Identities = 89/377 (23%), Positives = 165/377 (43%), Gaps = 35/377 (9%)
Query: 123 QNEFKPTELFEILSSSDDFSCEELASDWLDSYIDNRNVSLANLINFLLDCSGCFTHIGEH 182
QN + LFE++ + + + DW++SY +R+++L +LINF + CSGC +
Sbjct: 7 QNGVENMMLFEVVKMGKS-AMQSVVDDWIESYKHDRDIALLDLINFFIQCSGC-KGVVTA 64
Query: 183 DVANNDSSNETIGEIQIMFHEQKKHEFHLLLSATHKKAKFRPLNDNFNIFMTTLMDLAIE 242
++ + ++E I ++ F E ++ L ++ K KF+ +F F+ L+ +
Sbjct: 65 EMFRHMQNSEIIRKMTEEFDEDSG-DYPLTMAGPQWK-KFK---SSFCEFIGVLVRQC-Q 118
Query: 243 KEMIYVENEKEESDEIVIETNPLIIDLLTWIPSMSVSKIRCLRYVSAKAIFCFQDXXXXX 302
+IY DE +++T +I LLT +S S++R R+ S A
Sbjct: 119 YSIIY--------DEYMMDT---VISLLT---GLSDSQVRAFRHTSTLAAMKLM--TALV 162
Query: 303 XXXXXXXVLFXXXXXXXXXXXXXXXXXXXXXXXESSIS---DAEATKTVIENTIDNIIKL 359
+ E + + + + IEN ++ I K
Sbjct: 163 NVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKG 222
Query: 360 CFVHRFKDVDENIRSLAISYLLDWIENNPDYFFKVTFLKYFGWLLSDSSNSVRLQVIRSL 419
FVHR++D IR++ I + W++ D F ++LKY GW + D VRL+ + +L
Sbjct: 223 VFVHRYRDAIREIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTAL 282
Query: 420 HDLIKFSNKRNKNTVDNAALRQFFERFKDRMLEIA-GRDIDIQVRLTSVQVLSSINGLGY 478
L + NK N+ L F RFKDR++ + ++ D+ V+ + L +
Sbjct: 283 QGL--YYNKEL-----NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEV 335
Query: 479 LDDHEIIDIISLIFFDH 495
L + ++ L++ H
Sbjct: 336 LTAEDCENVYHLVYSAH 352
>Hs6912686 [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 1225
Score = 77.0 bits (188), Expect = 1e-13
Identities = 83/374 (22%), Positives = 153/374 (40%), Gaps = 35/374 (9%)
Query: 123 QNEFKPTELFEILSSSDDFSCEELASDWLDSYIDNRNVSLANLINFLLDCSGCFTHIGEH 182
Q+E +LF + ++ + L +WLDSY +++ L+NF + GC I
Sbjct: 92 QSEPPANDLFNAVKAAKS-DMQSLVDEWLDSYKQDQDAGFLELVNFFIQSCGC-KGIVTP 149
Query: 183 DVANNDSSNETIGEIQIMFHEQKKHEFHLLLSATHKKAKFRPLNDNFNIFMTTLMDLAIE 242
++ S++E I + F+E + L++ KF+ +F F+ TL+ +
Sbjct: 150 EMFKKMSNSEIIQHLTEQFNEDSGD--YPLIAPGPSWKKFQ---GSFCEFVRTLV-CQCQ 203
Query: 243 KEMIYVENEKEESDEIVIETNPLIIDLLTWIPSMSVSKIRCLRYVSAKAIFCFQDXXXXX 302
++Y D ++ DL++ + +S S++R R+ S A
Sbjct: 204 YSLLY--------DGFPMD------DLISLLTGLSDSQVRAFRHTSTLAAMKLM--TSLV 247
Query: 303 XXXXXXXVLFXXXXXXXXXXXXXXXXXXXXXXXESSIS---DAEATKTVIENTIDNIIKL 359
V ES + + + + IE ++ + +
Sbjct: 248 KVALQLSVHQDNNQRQYEAERNKGPGQRAPERLESLLEKRKELQEHQEEIEGMMNALFRG 307
Query: 360 CFVHRFKDVDENIRSLAISYLLDWIENNPDYFFKVTFLKYFGWLLSDSSNSVRLQVIRSL 419
FVHR++DV IR++ I + W+++ F ++LKY GW L D VR++ +++L
Sbjct: 308 VFVHRYRDVLPEIRAICIEEIGCWMQSYSTSFLTDSYLKYIGWTLHDKHREVRVKCVKAL 367
Query: 420 HDLIKFSNKRNKNTVDNAALRQFFERFKDRMLE-IAGRDIDIQVRLTSVQVLSSINGLGY 478
L N A L F RFKDRM+ I R+ + V + +L N G
Sbjct: 368 KGLY-------GNRDLTARLELFTSRFKDRMVSMIMDREYSVAVEAVRLLILILKNMEGL 420
Query: 479 LDDHEIIDIISLIF 492
L D + + +++
Sbjct: 421 LTDADCESVYPVVY 434
>ECU04g0870 [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 685
Score = 68.2 bits (165), Expect = 7e-11
Identities = 39/142 (27%), Positives = 74/142 (51%), Gaps = 14/142 (9%)
Query: 348 VIENTIDNIIKLCFVHRFKDVDENIRSLAISYLLDWIENNPDYFFKVTFLKYFGWLLSDS 407
V+E D + F+ RF+DVD NIR++ + ++ +W+ + P F +LKY GW LSD
Sbjct: 124 VVETMYDEV----FLVRFRDVDFNIRAVCVEFMCEWVVSVPGIFNSSCYLKYIGWALSDK 179
Query: 408 SNSVRLQVIRSLHDLIKFSNKRNKNTVDNAALRQFFERFKDRMLEIAGRDIDIQVRLTSV 467
+++VR + + S L++ +++ F RFK RM+E+A D + +R
Sbjct: 180 NDTVRRRGVSSCIRLVQ----------KKISVQAFVSRFKSRMIELALYDRNPGLRDEGK 229
Query: 468 QVLSSINGLGYLDDHEIIDIIS 489
+ S+ G + ++ +++
Sbjct: 230 ALCMSLYISGMISKDDVYKVLA 251
>At2g47980 [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 921
Score = 67.4 bits (163), Expect = 1e-10
Identities = 40/145 (27%), Positives = 73/145 (49%), Gaps = 8/145 (5%)
Query: 347 TVIENTIDNIIKLCFVHRFKDVDENIRSLAISYLLDWIENNPDYFFKVTFLKYFGWLLSD 406
T +E+ + I FVHR++D+D +IR I L WI + P F + +LKY GW L+D
Sbjct: 157 TTLEDMMRKIFTGLFVHRYRDIDNDIRMSCIQSLGIWILSYPSLFLQDLYLKYLGWTLND 216
Query: 407 SSNSVRLQVIRSLHDLIKFSNKRNKNTVDNAALRQFFERFKDRMLEIAGRDIDIQVRLTS 466
+ VR + +L L + + L F +RF +RM+E+A D+D+ + +
Sbjct: 217 KNAGVRKASLLALQKLYEMDE-------NVPTLGLFTQRFSNRMIEMAD-DVDMSAAVCA 268
Query: 467 VQVLSSINGLGYLDDHEIIDIISLI 491
+ ++ + + D ++ + L+
Sbjct: 269 IGLVKQLLRHQLIPDDDLGPLYDLL 293
>SPCC4E9.01c [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 862
Score = 66.2 bits (160), Expect = 3e-10
Identities = 104/488 (21%), Positives = 193/488 (39%), Gaps = 81/488 (16%)
Query: 80 PNSGGRRVASNKRTKLKQNEKGRPSNNISSAVSRKEQEAYISLQNEFKPTELFEILSSSD 139
P+ R+ + L +NE+ +N I + +E +++ + P E F L D
Sbjct: 44 PSEKKRKWGTQDEFSLTENEE---NNEIET-----NEEMHVNSHDYAFPQEFFLKLLDID 95
Query: 140 DFSCEELASDWLDSYIDNRNVSLANLINFLLDCSGCFTHIGEHDVANNDSSNETIGEI-Q 198
E+L+ + + Y N + INF L SGC + DV + DS ET+ ++ +
Sbjct: 96 -MPLEQLSQHYFEDYKSNSADFMLTFINFALVASGCQPFVTNFDVQDVDSIPETLSQVNR 154
Query: 199 IMFHEQKKHEFHLLLSATHKKAKFRPLNDNFNIFMTTLMDLAIEKEMIYVENEKEESDEI 258
F + L ++ K+AK + F +F+ + +YVE+ +
Sbjct: 155 SSFQKSSCAYTDYLYTSNSKEAK--TVRIRFQLFLVEFIS------KVYVEDAF--LGDS 204
Query: 259 VIETNPLIIDLLTWIPSMSVSKIRCLRYVSAKAIFCFQDXXXXXXXXXXXXVLFXXXXXX 318
+ET WI +M+ S +R+ +A I C
Sbjct: 205 FMETTK------AWIFTMTTSPWMLVRH-TATTICC------------------------ 233
Query: 319 XXXXXXXXXXXXXXXXXESSISDAE--ATKTVIENTIDNIIKLC---FVHRFKDVDENIR 373
E S AE + + ID I +C R D+ +IR
Sbjct: 234 ---DIMRCLCLIVNKLSEKSNQTAEILVLRDLTSRFIDMIHDICDSVLFSRIHDIRASIR 290
Query: 374 SLAISYLLDWIENNPDYFFKVTFLKYFGWLLSDSSNSVRLQVIRSLHDLIKFSNKRNKNT 433
+ ++ L D + P Y +++ GW LSD+ + +R ++ + L +++++
Sbjct: 291 IVCVTALYDCCQLLPTYLINRNLIRHSGWGLSDAESQIRKISLKIIDYLSSHEPEKDQDF 350
Query: 434 VDNAALRQFFERFKDRMLEIAGRDIDIQVRLTSVQVLS------SINGLGYLDDHEIIDI 487
V + F +RF R++EI DID VR +++ S+NG + I+I
Sbjct: 351 VVD-----FLDRFSLRIVEICRYDID-SVRSVALKTCEKLMEKISLNG-------KCINI 397
Query: 488 ISLIFFDHEVKVSSSSRDVKFLNEVTKFLANIVSEKTEEFLINN--ERFKVPVISVTEEQ 545
+S FD + + S+ + + ++ AN KT ++ R K+P++ + E
Sbjct: 398 VSSCIFDGKPQNRISTMRILVAHTNERY-ANYCEAKTATISLSKLLRREKIPLLVSSFES 456
Query: 546 FVKVGVLM 553
K+ L+
Sbjct: 457 LFKMNALL 464
>CE05664 [D] KOG2011 Sister chromatid cohesion complex Cohesin subunit
STAG/IRR1/SCC3
Length = 1096
Score = 64.3 bits (155), Expect = 1e-09
Identities = 37/122 (30%), Positives = 65/122 (52%), Gaps = 8/122 (6%)
Query: 349 IENTIDNIIKLCFVHRFKDVDENIRSLAISYLLDWIENNPDYFFKVTFLKYFGWLLSDSS 408
I I + + FVHR++DV +IR + I L W++ P++F + ++LKY GW + D
Sbjct: 308 IRQIIGYLFRSVFVHRYRDVVPDIRCICIQELGHWMDVYPEHFVEDSYLKYIGWSMFDKV 367
Query: 409 NSVRLQVIRSLHDLIKFSNKRNKNTVDNAALRQFFERFKDRMLEIAGRDIDIQVRLTSVQ 468
VR + IR+L L + T+ L F +FKDR++ + D D++ + +V
Sbjct: 368 GDVRQRCIRALIPLF-------EKTLILDKLELFVNKFKDRLVSML-LDKDLETSIETVH 419
Query: 469 VL 470
++
Sbjct: 420 LM 421
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,321,531
Number of Sequences: 60738
Number of extensions: 2458296
Number of successful extensions: 8004
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 7963
Number of HSP's gapped (non-prelim): 24
length of query: 1101
length of database: 30,389,216
effective HSP length: 117
effective length of query: 984
effective length of database: 23,282,870
effective search space: 22910344080
effective search space used: 22910344080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)