ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7410 good S KOG2650 Function unknown Zinc carboxypeptidase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7410 2583179 2584504 442
(442 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR132c [S] KOG2650 Zinc carboxypeptidase 548 e-156
SPBC337.07c [S] KOG2650 Zinc carboxypeptidase 261 1e-69
7290631 [S] KOG2650 Zinc carboxypeptidase 199 9e-51
Hs10047106 [S] KOG2650 Zinc carboxypeptidase 195 1e-49
Hs4502999 [S] KOG2650 Zinc carboxypeptidase 189 5e-48
Hs4503001 [S] KOG2650 Zinc carboxypeptidase 187 3e-47
CE28645 [S] KOG2650 Zinc carboxypeptidase 181 3e-45
Hs4502997 [S] KOG2650 Zinc carboxypeptidase 179 6e-45
7303399 [S] KOG2650 Zinc carboxypeptidase 174 2e-43
Hs17939400 [S] KOG2650 Zinc carboxypeptidase 167 2e-41
7297274 [S] KOG2650 Zinc carboxypeptidase 167 2e-41
Hs4503003 [S] KOG2650 Zinc carboxypeptidase 165 1e-40
Hs4503005 [S] KOG2650 Zinc carboxypeptidase 164 3e-40
7297555 [S] KOG2650 Zinc carboxypeptidase 160 3e-39
7297275 [S] KOG2650 Zinc carboxypeptidase 159 6e-39
7290634_2 [S] KOG2650 Zinc carboxypeptidase 159 8e-39
7304125 [S] KOG2650 Zinc carboxypeptidase 154 3e-37
Hs17447410 [S] KOG2650 Zinc carboxypeptidase 152 1e-36
7297556 [S] KOG2650 Zinc carboxypeptidase 152 1e-36
CE25665 [S] KOG2650 Zinc carboxypeptidase 151 2e-36
CE28646 [S] KOG2650 Zinc carboxypeptidase 150 4e-36
CE20027 [S] KOG2650 Zinc carboxypeptidase 146 7e-35
7295241 [S] KOG2650 Zinc carboxypeptidase 146 7e-35
CE09182 [S] KOG2650 Zinc carboxypeptidase 145 9e-35
7300993 [S] KOG2650 Zinc carboxypeptidase 143 4e-34
CE24363 [S] KOG2650 Zinc carboxypeptidase 143 6e-34
CE20329 [S] KOG2650 Zinc carboxypeptidase 139 1e-32
7295238 [S] KOG2650 Zinc carboxypeptidase 138 1e-32
7295316 [S] KOG2650 Zinc carboxypeptidase 134 2e-31
7295242 [S] KOG2650 Zinc carboxypeptidase 134 2e-31
7290632 [S] KOG2650 Zinc carboxypeptidase 134 2e-31
7295243 [S] KOG2650 Zinc carboxypeptidase 134 4e-31
7295240 [S] KOG2650 Zinc carboxypeptidase 132 1e-30
7295239 [S] KOG2650 Zinc carboxypeptidase 132 1e-30
7293312 [S] KOG2650 Zinc carboxypeptidase 130 4e-30
7295225 [S] KOG2650 Zinc carboxypeptidase 115 1e-25
CE26965 [S] KOG2650 Zinc carboxypeptidase 109 9e-24
CE06536 [S] KOG2650 Zinc carboxypeptidase 108 2e-23
Hs9966831 [S] KOG2650 Zinc carboxypeptidase 100 4e-21
Hs16915928 [S] KOG2650 Zinc carboxypeptidase 90 6e-18
CE28480 [R] KOG2649 Zinc carboxypeptidase 63 1e-09
7293271 [R] KOG2649 Zinc carboxypeptidase 53 8e-07
7290047 [R] KOG2649 Zinc carboxypeptidase 50 5e-06
>YHR132c [S] KOG2650 Zinc carboxypeptidase
Length = 430
Score = 548 bits (1413), Expect = e-156
Identities = 263/440 (59%), Positives = 337/440 (75%), Gaps = 19/440 (4%)
Query: 7 TLWVINLIVLFTNTAEAR----DYSNYKVCRFNDESQFSVIISKLKDIAMIKQEYEFDIW 62
+LW L VL T + DYS Y V RF ++ +S ++ + IA + +Y D+W
Sbjct: 6 SLWGCFLFVLLAVTGAVQGLQEDYSEYAVYRFTSDN-YSTLVRDV--IAPLTDDY--DVW 60
Query: 63 AKSKSHGFMDIRMHDDILEQFPSCDIIIEDLNSVISETKSAVGGETSNDARTQSFFDAES 122
++S+ F+DI++ +I EQ +II+++N +I T + AR Q+ F+ +
Sbjct: 61 --TRSNNFIDIKLPKEIGEQINDGQVIIDNMNELIQNTLPT----SQMMAREQAVFENDY 114
Query: 123 KRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNP 182
D FF+EYRDLDTIY WLDLL+ SFP LV VE G+TFEGR+LKALHIS N E NP
Sbjct: 115 ----DFFFNEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGNKPESNP 170
Query: 183 DKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYV 242
+KKTI+ITGG+HAREW+SVSTVC+ ++QLL RYG SK ET++LD LDFL+IPVFNPDGY
Sbjct: 171 EKKTIVITGGIHAREWISVSTVCWALYQLLNRYGSSKKETKYLDDLDFLVIPVFNPDGYA 230
Query: 243 YTWTHDRLWRKNRQQTYFPRCFGIDIDHSFDFQWTGSNDFPCSESYSGESPFEALEAESW 302
YTW+HDRLWRKNRQ+T+ P+C GIDIDHSF FQW ++ CSE YSGE+PFEA EA +W
Sbjct: 231 YTWSHDRLWRKNRQRTHVPQCLGIDIDHSFGFQWEKAHTHACSEEYSGETPFEAWEASAW 290
Query: 303 DEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSG 362
+Y+N+ K +Y I+GY+D HSY+QE+LYPY YSCDALPRDLENLLELSYGLSKAIR KSG
Sbjct: 291 YKYINETKGDYKIYGYIDMHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSG 350
Query: 363 KGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPV 422
+ Y V+S+C+DRGSD+ PGLG+GSALD+MYHHRA+WAFQLKLRDTGNHGFLLPP+ I PV
Sbjct: 351 RNYDVISACKDRGSDIFPGLGAGSALDFMYHHRAHWAFQLKLRDTGNHGFLLPPENIKPV 410
Query: 423 GEEIYAAVQYFCEFILNPDL 442
G+E YAA++YFC+F+L+P++
Sbjct: 411 GKETYAALKYFCDFLLDPEI 430
>SPBC337.07c [S] KOG2650 Zinc carboxypeptidase
Length = 497
Score = 261 bits (668), Expect = 1e-69
Identities = 157/432 (36%), Positives = 237/432 (54%), Gaps = 30/432 (6%)
Query: 25 DYSNYKVCRFNDESQFSVIISKLKDIAMIKQEYEFDIWAKSKSHGFMDIRMHDDILEQFP 84
DY+ V R + E + + L DI Q DIW + H +D+R+ ++ + +
Sbjct: 72 DYNEEIVVRLHLEEE-----NNLSDILQKAQSQNLDIWDYNFDH--VDLRLKEENFDFWK 124
Query: 85 S---CDIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRP---------KDIFFDE 132
S DI+I +L + E S V T++ T++F A DIFF
Sbjct: 125 SQYRSDILINNLTETLFE--SIVPDTTNSPFSTEAFLQAVENGHLNHEMFTSFTDIFFKS 182
Query: 133 YRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHIS----TNNVEKNPDKKTII 188
Y++L++I +WL L+ + DL + G T EGR + L ++ ++N EK +KK II
Sbjct: 183 YQNLESINSWLRLMASLYKDLSELVPVGITAEGRTILGLKLNGRHPSDNGEKIRNKKVII 242
Query: 189 ITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHD 248
I GG HAREW+ + +VCY +QLL +Y + LD +++ IPV N DGY YTW++D
Sbjct: 243 IQGGSHAREWIGIPSVCYAAWQLLAKYDSDGHVRKLLDKFEWIFIPVLNVDGYEYTWSND 302
Query: 249 RLWRKNRQQTYFPRCFGIDIDHSFDFQWTGSNDFPCSESYSGESPFEALEAESWDEYVNK 308
RLW KNRQ CFGI++D ++ F + G+ D PCS Y G SPF+A E + + +
Sbjct: 303 RLWSKNRQPLNNSECFGINLDANWAFGFNGNID-PCSNEYGGLSPFQANETMALFNLITE 361
Query: 309 AKS--EYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYH 366
+ S + + G+LD HSY+Q VL+PY Y+CD P D EN EL+ GL K + R + + Y
Sbjct: 362 SLSQEQKKVVGFLDVHSYSQSVLWPYAYTCDLFPPDTENFEELAIGLVKELHRVNSRYYT 421
Query: 367 VLSSCEDRGSDLQPGLGSGSALDYMYHHR-AYWAFQLKLRDTGNHGFLLPPKFIVPVGEE 425
+C + L G+A+D++Y W F ++LRD G++G+LLP K IVP +E
Sbjct: 422 YQQACIPYDGFHKHYL-PGTAIDWVYFAADVAWPFNIRLRDMGDYGYLLPAKQIVPTAKE 480
Query: 426 IYAAVQYFCEFI 437
+A + Y+ EFI
Sbjct: 481 FFAMILYYGEFI 492
>7290631 [S] KOG2650 Zinc carboxypeptidase
Length = 440
Score = 199 bits (505), Expect = 9e-51
Identities = 130/402 (32%), Positives = 212/402 (52%), Gaps = 43/402 (10%)
Query: 52 MIKQEYEFDIWAKSKSHGFMDIRMHDDILEQFPSC--------DIIIEDLNSVISETKSA 103
M++Q++ +IW ++ F+DI + D L+ S I+ ++ S+I E
Sbjct: 60 MLEQKFGGNIWKENSK--FLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDE---- 113
Query: 104 VGGETSNDARTQSFFDAESKRPK-----DIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEW 158
E ++ SF +R K + + +Y DL+TIY+++ ++ FP++V +
Sbjct: 114 ---ELLEGIQSSSF--GHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYT 168
Query: 159 TGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKS 218
GQT EGRDLK L IS N E K + I GG+HAREW+S +TV + ++QL++ +
Sbjct: 169 IGQTAEGRDLKVLRISENPREN----KKVWIDGGIHAREWISPATVTFILYQLMSDWENQ 224
Query: 219 KTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGIDIDHSFDFQWT- 277
R L + I+PV NPDGY Y+ T +RLWRKNR + +C G+D++ +FD W
Sbjct: 225 PAHIR---GLTWYIMPVMNPDGYEYSRTTNRLWRKNRSPSRRAQCSGVDLNRNFDIGWNG 281
Query: 278 -GSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSC 336
GS+ PCS++Y G +P E + E++ AK +YN+ YL FHSY Q ++YP+ Y
Sbjct: 282 YGSSTNPCSDTYRGSAPASERETRAVAEFL--AKRKYNLESYLTFHSYGQMIVYPWAYKA 339
Query: 337 DALPRDLENLLELSYGLSKAIRRKSGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRA 396
+ +D L +S ++ I +K+G Y + E G+ G + D+
Sbjct: 340 VKV-KDASVLQRVSSLAAERILQKTGTSYRAAVTHE------VLGIAGGGSDDWSRAALG 392
Query: 397 Y-WAFQLKLRDTGNHGFLLPPKFIVPVGEEIYAAVQYFCEFI 437
+ + ++LRD G +GF+LPP+FI E + V+ + I
Sbjct: 393 VKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVVETVAQAI 434
>Hs10047106 [S] KOG2650 Zinc carboxypeptidase
Length = 421
Score = 195 bits (496), Expect = 1e-49
Identities = 113/352 (32%), Positives = 183/352 (51%), Gaps = 26/352 (7%)
Query: 88 IIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQ 147
+ IEDL +++ N+ + + + + + Y L+ IY +D +
Sbjct: 89 VTIEDLQALLD-----------NEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIA 137
Query: 148 LSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYT 207
FPDL G +FE R + L ST + P + + G+H+REW+S +T +T
Sbjct: 138 ADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRP---AVWLNAGIHSREWISQATAIWT 194
Query: 208 IFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGID 267
++++ Y + T L+ +D ++PV NPDGYVYT T +RLWRK R + C G D
Sbjct: 195 ARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGAD 254
Query: 268 IDHSFD--FQWTGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYA 325
+ +++ F G++D PCSE Y G +E +S +++ K N G++D HSY+
Sbjct: 255 PNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQK---HGNFKGFIDLHSYS 311
Query: 326 QEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSSCEDRGSDLQPGLGSG 385
Q ++YPYGYS P D E L +++ +KA+ SG Y V +C + + P SG
Sbjct: 312 QLLMYPYGYSVKKAP-DAEELDKVARLAAKALASVSGTEYQVGPTC----TTVYP--ASG 364
Query: 386 SALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPVGEEIYAAVQYFCEFI 437
S++D+ Y + +AF +LRDTG +GFLLP I+P EE + ++ E +
Sbjct: 365 SSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHV 416
>Hs4502999 [S] KOG2650 Zinc carboxypeptidase
Length = 417
Score = 189 bits (481), Expect = 5e-48
Identities = 118/395 (29%), Positives = 198/395 (49%), Gaps = 38/395 (9%)
Query: 54 KQEYEFDIWAKSKSHG--------FMDIRMHDDILE-QFPSCDIIIEDLNSVISETKSAV 104
++ + D W + G F++++ LE Q + I+IED+ ++ +
Sbjct: 45 QEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENE-- 102
Query: 105 GGETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFE 164
+ F+ +R + F Y L+ I +D L P LV+ G +FE
Sbjct: 103 ----------EMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFE 152
Query: 165 GRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRF 224
R + L ST DK I + G+HAREWV+ +T +T ++++ YGK + T
Sbjct: 153 NRPMNVLKFSTGG-----DKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSI 207
Query: 225 LDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGIDIDHSFD--FQWTGSNDF 282
LD LD ++PV NPDGYV++ T +R+WRK R + C G+D + ++D F G++
Sbjct: 208 LDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSN 267
Query: 283 PCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRD 342
PCS+SY G S +E +S +++ KS + ++ HSY+Q +++PYGY C L D
Sbjct: 268 PCSDSYHGPSANSEVEVKSIVDFI---KSHGKVKAFIILHSYSQLLMFPYGYKCTKLD-D 323
Query: 343 LENLLELSYGLSKAIRRKSGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAYWAFQL 402
+ L E++ ++++R G Y V C SG ++D+ Y + ++F
Sbjct: 324 FDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQ------ASGGSIDWSYDYGIKYSFAF 377
Query: 403 KLRDTGNHGFLLPPKFIVPVGEEIYAAVQYFCEFI 437
+LRDTG +GFLLP + I+P EE + ++ E +
Sbjct: 378 ELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 412
>Hs4503001 [S] KOG2650 Zinc carboxypeptidase
Length = 417
Score = 187 bits (475), Expect = 3e-47
Identities = 127/425 (29%), Positives = 206/425 (47%), Gaps = 50/425 (11%)
Query: 33 RFNDESQFSVIISKLKDIAMIK---QEYEFDIWAKSKSHG-----FMDIRMHDDILEQFP 84
RF+ E F V K +IK + E D W +H +D R+ + +
Sbjct: 20 RFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQ 79
Query: 85 SC--------DIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRPKDIFFDEYRDL 136
S +I+I DL I + FD + P + +Y +
Sbjct: 80 SALDQNKMHYEILIHDLQEEIEKQ-----------------FDVKEDIPGRHSYAKYNNW 122
Query: 137 DTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAR 196
+ I W + + +P++V+ G T E L L I EKN +K I + G+HAR
Sbjct: 123 EKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIG----EKNERRKAIFMDCGIHAR 178
Query: 197 EWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQ 256
EWVS + + ++Q YG++K T+ LD ++F I+PVFN DGY+++WT +R+WRKNR
Sbjct: 179 EWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRS 238
Query: 257 QTYFPRCFGIDIDHSFDFQWT---GSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEY 313
+ +C G D++ +F+ W +ND PC+++Y G +P E ++ ++ +E
Sbjct: 239 KNQNSKCIGTDLNRNFNASWNSIPNTND-PCADNYRGSAPESEKETKAVTNFIRSHLNEI 297
Query: 314 NIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSSCED 373
+ Y+ FHSY+Q +L+PYGY+ LP + E+L +++ + + + Y + E
Sbjct: 298 KV--YITFHSYSQMLLFPYGYT-SKLPPNHEDLAKVAKIGTDVLSTRYETRY-IYGPIE- 352
Query: 374 RGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPVGEEIYAAVQYF 433
S + P SGS+LD+ Y F +LRD G GFLLP I P E AV++
Sbjct: 353 --STIYP--ISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFI 408
Query: 434 CEFIL 438
++IL
Sbjct: 409 AKYIL 413
>CE28645 [S] KOG2650 Zinc carboxypeptidase
Length = 584
Score = 181 bits (458), Expect = 3e-45
Identities = 127/436 (29%), Positives = 213/436 (48%), Gaps = 51/436 (11%)
Query: 19 NTAEARDYSNYKVCRFNDESQFSVIISKLKDIAMIKQEYEFDIWAKSKSHG-FMDIRMHD 77
NT + Y N+K+ R N E++ SV L+ + YE D W + G +D+ +
Sbjct: 22 NTDDNAGYHNFKLIRINPETEGSV--KYLRSLYEDPSPYELDFWQPPTNIGAIVDLTVAP 79
Query: 78 DILEQFPSCDIIIEDLNS-------VISETKSAVGGETSNDARTQSFFDAESKRPKDIFF 130
+F ++DL S +++ A+ E +D F++ + +
Sbjct: 80 ADAPRF------VKDLESKKISYIVAVNDLSKAIENERGSD----KFYNPVA----GFAY 125
Query: 131 DEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNP--DKKTII 188
D+Y L+ I T + L+ +P ++T+ GQ+ E R L + I+ ++NP K ++
Sbjct: 126 DKYNSLEEIQTEMKRLKKEYPTMITLIDIGQSHENRTLLVMKITG---KRNPLGSKISMW 182
Query: 189 ITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHD 248
I G+HAREW++ +T Y +LL Y T + +DH+DF I+PV NPDGY Y+ +
Sbjct: 183 IDAGIHAREWIAPATAMYIAHELLLGYENDATVAKLMDHIDFYILPVMNPDGYEYSREKN 242
Query: 249 RLWRKNRQQTYFPR-------CFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALEA 299
R+WRKNR R C G+D++ +FD+ W TGS+ PC ++Y G + F E+
Sbjct: 243 RMWRKNRSPAKCARQTFSTVCCSGVDLNRNFDWFWASTGSSSDPCHDTYHGSAAFSEPES 302
Query: 300 ESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLE-NLLELSYGLSKAIR 358
++ +++ + E ++ HSY+Q L PYG+ + P+D L L+ +KA+
Sbjct: 303 QAVRDFLEQNTPE----AFISLHSYSQMWLIPYGHRKQSYPQDYHTGLRPLALRATKALY 358
Query: 359 RKSGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTG---NHGFLLP 415
G Y V G+DL GS + +A+ ++LR HGFLLP
Sbjct: 359 ELYGTKYQV-----GTGADLMYEASGGSHDWAKGQLKVPYAYLIELRPKNTMMGHGFLLP 413
Query: 416 PKFIVPVGEEIYAAVQ 431
+ IVP G E + +++
Sbjct: 414 EREIVPTGLETFESIK 429
>Hs4502997 [S] KOG2650 Zinc carboxypeptidase
Length = 419
Score = 179 bits (455), Expect = 6e-45
Identities = 135/435 (31%), Positives = 213/435 (48%), Gaps = 33/435 (7%)
Query: 13 LIVLFTNTAEARDYSNYKVCRFN--DESQFSVIISKLKDIAMIKQEYEFDIWAKSKSHGF 70
L VL D+ ++V R + DE+Q + K+K++ + + + D W + +H
Sbjct: 7 LSVLLGAVFGKEDFVGHQVLRISVADEAQ----VQKVKELEDL-EHLQLDFW-RGPAHPG 60
Query: 71 MDIRMHDDILEQFPSCDIIIEDLNS--VISETKSAVGGETSNDARTQSFFDAESKRPKDI 128
I D+ FPS + L S + ET ++ + Q F R D
Sbjct: 61 SPI----DVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDT 116
Query: 129 F-FDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTI 187
F + Y L+ IY +LDLL P LV+ G T+EGR + L ST K P I
Sbjct: 117 FNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGG-SKRP---AI 172
Query: 188 IITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTH 247
I G+H+REWV+ ++ + ++ YG+ T LD LD + V NPDG+ +T +
Sbjct: 173 WIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHST 232
Query: 248 DRLWRKNRQQTYFPRCFGIDIDHSFD--FQWTGSNDFPCSESYSGESPFEALEAESWDEY 305
+R+WRK R T C G+D + ++D F +G++ PCSE+Y G+ +E +S ++
Sbjct: 233 NRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDF 292
Query: 306 VNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGY 365
V K NI ++ HSY+Q ++YPYGY + +P D + L +LS A+ G +
Sbjct: 293 V---KDHGNIKAFISIHSYSQLLMYPYGYKTEPVP-DQDELDQLSKAAVTALASLYGTKF 348
Query: 366 HVLSSCEDRGSDLQP-GLGSGSALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPVGE 424
+ GS ++ SGS +D+ Y ++F +LRDTG +GFLLP I+P +
Sbjct: 349 NY-------GSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAK 401
Query: 425 EIYAAVQYFCEFILN 439
E + A+ E LN
Sbjct: 402 ETWLALLTIMEHTLN 416
>7303399 [S] KOG2650 Zinc carboxypeptidase
Length = 422
Score = 174 bits (441), Expect = 2e-43
Identities = 111/353 (31%), Positives = 179/353 (50%), Gaps = 43/353 (12%)
Query: 87 DIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLL 146
++I++DL +I E S+VG ++ + T Y LDTIY W+D
Sbjct: 92 EVIVDDLQKLIDE--SSVGDDSQMEWET------------------YHTLDTIYDWIDQ- 130
Query: 147 QLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCY 206
+ + D + + GQ++EGRD+K++ +S K K I + G +HA EW+S +TV +
Sbjct: 131 ECAAHDFLECKVIGQSYEGRDIKSIRLS-----KRSGNKAIFLEGNIHAMEWISSATVTF 185
Query: 207 TIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPR---- 262
+ QL+ + R + D++++P+ NPDG+VYT +RLWRKNR+ +
Sbjct: 186 LLNQLIN--SEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNGYRNESGD 243
Query: 263 CFGIDIDHSFDFQWTGSN---DFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYL 319
C+GID++ +FD+ W G+ D PC + GE P +E S +V+ + Y I Y+
Sbjct: 244 CYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGY-IRSYM 302
Query: 320 DFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSSCEDRGSDLQ 379
+H+Y Q VL PYG+S P + E + ++ S A G S+ S L
Sbjct: 303 AYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYG------STFTYGASGLL 356
Query: 380 PGLGSGSALDYMYH-HRAYWAFQLKLRDTGNHGFLLPPKFIVPVGEEIYAAVQ 431
+ SG+A D+ Y + + ++LRD G GF LP I VG E+ A ++
Sbjct: 357 NYVVSGAAKDWAYGVKKIPFTCTVELRDKGTFGFFLPSNQITEVGLEVTAGLK 409
>Hs17939400 [S] KOG2650 Zinc carboxypeptidase
Length = 436
Score = 167 bits (424), Expect = 2e-41
Identities = 108/354 (30%), Positives = 177/354 (49%), Gaps = 27/354 (7%)
Query: 88 IIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQ 147
I+I+D+ ++ E + A+ + T SF + Y L+ IY+W+D
Sbjct: 105 IMIKDIQVLLDEERQAMAKSRRLERSTNSFS-----------YSSYHTLEEIYSWIDNFV 153
Query: 148 LSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYT 207
+ D+V+ G +FE + + L ST ++P I I G+H+REW++ +T +T
Sbjct: 154 MEHSDIVSKIQIGNSFENQSILVLKFSTGG-SRHP---AIWIDTGIHSREWITHATGIWT 209
Query: 208 IFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGID 267
++++ YGK + T L+ +D I V NPDG+ +T + +RLWRKN+ C G+D
Sbjct: 210 ANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVD 269
Query: 268 IDHSF--DFQWTGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYA 325
++ ++ F GSN PCSE+Y G SP E + VN + N + HSY+
Sbjct: 270 LNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAA---IVNFITAHGNFKALISIHSYS 326
Query: 326 QEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSSCEDRGSDLQPGLGSG 385
Q ++YPYG + + E L +L+ +A+ + G Y + S + SG
Sbjct: 327 QMLMYPYGRLLEPVSNQRE-LYDLAKDAVEALYKVHGIEY-IFGSI-----STTLYVASG 379
Query: 386 SALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPVGEEIYAAVQYFCEFILN 439
+D+ Y +AF +LRDTG +GFLLP I+P +E + A++ E LN
Sbjct: 380 ITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLN 433
>7297274 [S] KOG2650 Zinc carboxypeptidase
Length = 422
Score = 167 bits (424), Expect = 2e-41
Identities = 118/438 (26%), Positives = 218/438 (48%), Gaps = 55/438 (12%)
Query: 8 LWVINLIVLFTNTAEARD-----YSNYKVCRFNDESQFSVIISKLKDIAMIKQEYEFDIW 62
LW++ +V T+ +D Y N++V + +++ ++ ++ I + ++Y +IW
Sbjct: 4 LWLLATLVALTSAGILKDSPKERYDNFRVYKLTIQNKIQ--LAAIEKIGELTKKY--NIW 59
Query: 63 AKSKSHGF-MDIRMHDDILEQFP--------SCDIIIEDLNSVISETKSAVGGETSNDAR 113
+ +DI + L F S +++IE++ I E + +++
Sbjct: 60 KEYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADSATFGW 119
Query: 114 TQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHI 173
T+ Y +L+ I WLD + ++P + G+++EGR ++ + I
Sbjct: 120 TK-----------------YYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKI 162
Query: 174 STNNVEKNPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFL-DHLDFLI 232
S + NP I I +HAREW++ ++ + I QLLT + R L D+ D+ I
Sbjct: 163 S--HKAGNPG---IFIESNIHAREWITSASATWFINQLLT---SEDADVRSLADNYDWHI 214
Query: 233 IPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGIDIDHSFDFQW---TGSNDFPCSESYS 289
IPVFN DG+ Y+ DR+WRK RQ C G D + +FD W G++D PCSE+++
Sbjct: 215 IPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADANRNFDSYWLQNNGASDNPCSETFA 274
Query: 290 GESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLEL 349
G++P EA++ EY+ K + + ++ Y+ FHSY Q +L PYG++ + P + ++L +
Sbjct: 275 GDNPESEPEAKALVEYLTKIQDQISV--YISFHSYGQYLLSPYGHTNEEFPENYNDILTI 332
Query: 350 SYGLSKAIRRKSGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRA-YWAFQLKLRDTG 408
+ AI + S D + +G+++D++++ + ++ RD G
Sbjct: 333 GKAFADAIEALPYGTVYQYGSTAD-----VLYVATGTSVDWVFNELGKKIGYTIEYRDKG 387
Query: 409 NHGFLLPPKFIVPVGEEI 426
+GF+LPP I+P EE+
Sbjct: 388 RYGFILPPVQIIPNCEEL 405
>Hs4503003 [S] KOG2650 Zinc carboxypeptidase
Length = 416
Score = 165 bits (418), Expect = 1e-40
Identities = 124/448 (27%), Positives = 208/448 (45%), Gaps = 52/448 (11%)
Query: 6 LTLWVINLIVLFTNTAEARDYSNYKVCRFNDESQFSVIISKLKDIAMIKQEYEFDIW--- 62
L L V+ + L + + KV R N E + + I ++++A Q D W
Sbjct: 2 LALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINI--IRELASTTQ---IDFWKPD 56
Query: 63 --AKSKSHGFMDIRMH-------DDILEQFP-SCDIIIEDLNSVISETKSAVGGETSNDA 112
+ K H +D R+ +++L+Q ++I +L +V+ E D+
Sbjct: 57 SVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVV---------EAQFDS 107
Query: 113 RTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALH 172
R ++ + +++Y +TI W + P L++ G TFEGR + L
Sbjct: 108 RVRATGHS---------YEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLK 158
Query: 173 ISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLI 232
+ + +K I + G HAREW+S + + + + + YG+ T LD LDF +
Sbjct: 159 VG----KAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYV 214
Query: 233 IPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSG 290
+PV N DGY+YTWT R WRK R T+ G D + +FD W G++ PC E+Y G
Sbjct: 215 LPVLNIDGYIYTWTKSRFWRKTR-STHTGSSIGTDPNRNFDAGWCEIGASRNPCDETYCG 273
Query: 291 ESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELS 350
+ E ++ +++ S +I YL HSY+Q ++YPY Y+ + EN EL+
Sbjct: 274 PAAESEKETKALADFIRNKLS--SIKAYLTIHSYSQMMIYPYSYAY----KLGENNAELN 327
Query: 351 YGLSKAIRRKSGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTGNH 410
L+KA ++ + + + + P G D+ Y ++F +LRDTG +
Sbjct: 328 -ALAKATVKELASLHGTKYTYGPGATTIYPAAGGSD--DWAYDQGIRYSFTFELRDTGRY 384
Query: 411 GFLLPPKFIVPVGEEIYAAVQYFCEFIL 438
GFLLP I EE + A++Y ++L
Sbjct: 385 GFLLPESQIRATCEETFLAIKYVASYVL 412
>Hs4503005 [S] KOG2650 Zinc carboxypeptidase
Length = 423
Score = 164 bits (414), Expect = 3e-40
Identities = 108/350 (30%), Positives = 175/350 (49%), Gaps = 33/350 (9%)
Query: 86 CDIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDL 145
C +++ D+ +I + + SND S R ++++Y L+ IY+W++
Sbjct: 91 CSVLLADVEDLIQQ-------QISNDT--------VSPRASASYYEQYHSLNEIYSWIEF 135
Query: 146 LQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVC 205
+ PD++T G +FE L L +S ++ K I I G+HAREW+S +
Sbjct: 136 ITERHPDMLTKIHIGSSFEKYPLYVLKVSG---KEQTAKNAIWIDCGIHAREWISPAFCL 192
Query: 206 YTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFG 265
+ I + YG T L +DF ++PV N DGY Y+W +R+WRKNR C G
Sbjct: 193 WFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIG 252
Query: 266 IDIDHSF-DFQW--TGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFH 322
D++ +F W G++ CSE+Y G P E ++ ++ + ++ I Y+ H
Sbjct: 253 TDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQ--IKAYISMH 310
Query: 323 SYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIR--RKSGKGYHVLSSCEDRGSDLQP 380
SY+Q +++PY Y+ + +D E ELS S+A+R K+ K L P
Sbjct: 311 SYSQHIVFPYSYT-RSKSKDHE---ELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAP 366
Query: 381 GLGSGSALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPVGEEIYAAV 430
G G D++Y ++F ++LRDTG +GFLLP ++I P E +AAV
Sbjct: 367 GGGD----DWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAV 412
>7297555 [S] KOG2650 Zinc carboxypeptidase
Length = 424
Score = 160 bits (406), Expect = 3e-39
Identities = 124/431 (28%), Positives = 214/431 (48%), Gaps = 41/431 (9%)
Query: 6 LTLWVINLIVLFTNTAEARDYSNYKVCRFNDESQFSVIISKLKDIAMIKQEYEFDIWAKS 65
L L ++++ +L AE + + NYKV R + V ++L+ + ++ E + +
Sbjct: 3 LLLLLLSVNILIFCLAERQRFDNYKVYRVSP-----VKANQLEGLRSLEANSEDALVLNN 57
Query: 66 KSHGFMDIRMHDDILEQFPSCDIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRP 125
G D + D F +++DL+ +S +TS + DA ++R
Sbjct: 58 LHLGPTDFLVAPDFDGTFLK---LVKDLD--LSPELIDANAQTSLSLDIEPIADA-NRRS 111
Query: 126 KDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKK 185
D + EY +L+ + W+ L +PD+V+V GQ++EGR+L L I+ N + +K+
Sbjct: 112 DDYSWSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHN--DGRAEKQ 169
Query: 186 TIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTW 245
+I + G+HAREW+ +T Y +LL+ + + + I+P NPDGYVYT
Sbjct: 170 SIFLEAGMHAREWIGPATATYFANELLS--SQQQEIMNLARSYVWYILPHANPDGYVYTH 227
Query: 246 THDRLWRKNRQQTYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALEAESWD 303
+R+WRK R C G D + ++DF W G++ PCSESY+G F E ++
Sbjct: 228 KTNRMWRKTR-SPQDKNCVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLS 286
Query: 304 EYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALP---RDLENLLELSYGLSKAIRRK 360
+++ + +L HS++Q +LYPYG++ ALP R LE + + G A++R+
Sbjct: 287 QFLKSVPEP--MFMFLSLHSFSQLLLYPYGHT-SALPENHRQLEQIFNTAVG---AMKRR 340
Query: 361 SGKGYHVLSSCEDRGSDLQPGL--GSGSALDYMYH-HRAYWAFQLKLRDTGNH---GFLL 414
G Y G ++ + +GS++D+ Y ++F +LR +G GF L
Sbjct: 341 YGTRY--------TGGNVYDAIYPAAGSSMDWAYGVLNVKYSFTYELRPSGYSFWTGFRL 392
Query: 415 PPKFIVPVGEE 425
P I+P G+E
Sbjct: 393 PAAQIIPTGQE 403
>7297275 [S] KOG2650 Zinc carboxypeptidase
Length = 419
Score = 159 bits (403), Expect = 6e-39
Identities = 113/434 (26%), Positives = 203/434 (46%), Gaps = 45/434 (10%)
Query: 10 VINLIVLFTNTAEARD----YSNYKVCRFNDESQFSVIISKLKDIAMIKQEYEFDIWAKS 65
V+ L+VL + +D Y NY V + E+Q I L+ +A ++ + AK
Sbjct: 9 VLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSI--LRKLAEDRENFRLWHEAKD 66
Query: 66 KSHGFMDIRMHDDILEQFPSCDIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRP 125
+ H + ++ + ++ E IS + + E + + + + R
Sbjct: 67 ELHLMLSPGAFGELETEIQKTNVTAE---LFISNVQELIDSEEAANLK--------ASRD 115
Query: 126 KDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKK 185
+ +Y L IY WLD + ++P + GQ++EGR ++ + IS + NP
Sbjct: 116 GTFGWTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKS--NNPG-- 171
Query: 186 TIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTW 245
++I +HAREW++ +T + I + LT + + ++ D+ I+PV N
Sbjct: 172 -VLIESNIHAREWITSATATWLINEFLTSTDELVRD--LAENHDWYIVPVLN-------- 220
Query: 246 THDRLWRKNRQQTYFPRCFGIDIDHSFDFQW---TGSNDFPCSESYSGESPFEALEAESW 302
DR+WRK RQ + C G D + ++D W G++ PC+E Y G PF E ++
Sbjct: 221 --DRMWRKTRQPSEISSCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAM 278
Query: 303 DEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSG 362
E+V K + N+ L FHSY+Q +L PYG++ + P + ++++E++ A+
Sbjct: 279 SEFVISIKDKINV--LLAFHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAV---ES 333
Query: 363 KGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAY-WAFQLKLRDTGNHGFLLPPKFIVP 421
Y + L P SG+ +D+ Y+ + ++ ++ RDTG +GF+LPP I+P
Sbjct: 334 LPYGTVYRYGSAAGILYP--ASGATIDWAYNEQGVEISYTIEFRDTGRYGFILPPVHIIP 391
Query: 422 VGEEIYAAVQYFCE 435
EE + E
Sbjct: 392 NAEEALIGIAALLE 405
>7290634_2 [S] KOG2650 Zinc carboxypeptidase
Length = 440
Score = 159 bits (402), Expect = 8e-39
Identities = 116/412 (28%), Positives = 204/412 (49%), Gaps = 42/412 (10%)
Query: 28 NYKVCRFNDESQFSVIISKLKDIAM---IKQEYEFDIWAKSKSHGFMDIRMHDDILEQFP 84
N + R++ + +++ KD M ++ +Y+ +W + K +D + +L
Sbjct: 25 NAHLRRYDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKEVKQE--VDYLLKPQVLAAAE 82
Query: 85 --------SCDIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRPKDIFFDEYRDL 136
S ++I++L VI + + + + ++++ + + Y L
Sbjct: 83 RHIRAANLSRIVLIDNLQRVIEK----------ENPPAEKIAELQNRKGHRLTWQAYHRL 132
Query: 137 DTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAR 196
+ I+ ++D + ++PD+ + E G + E R LK L IS N +NP I I GG+HAR
Sbjct: 133 EDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGNA-RNPG---IWIDGGMHAR 188
Query: 197 EWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQ 256
EW+S +TV Y QL+ + R +++ I PV NPDGY Y+ T DRLWRKN
Sbjct: 189 EWISPATVTYIANQLVEGWEDLPEHMR---SINWYIHPVANPDGYEYSHTTDRLWRKN-M 244
Query: 257 QTYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYN 314
+ + +C G+D++ +F ++W G++ PCS++Y G F E ++++ E
Sbjct: 245 RAHGRQCPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRE-T 303
Query: 315 IHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSSCEDR 374
YL FHSY Q +LYP+GY L +D +L ++ +I + +G Y V SS
Sbjct: 304 FQAYLSFHSYGQYILYPWGYDYQ-LTQDRADLDRVARQAGTSITKSTGVKYTVGSS---- 358
Query: 375 GSDLQPGLGSGSALDYMYHHRAY-WAFQLKLRDTGNHGFLLPPKFIVPVGEE 425
+ L P G D+ +A+ +++ DTG +GF+LP +FI G++
Sbjct: 359 ATTLYPAAGGSD--DWAKGIAGIKYAYTIEMGDTGRYGFVLPARFIQYNGKD 408
>7304125 [S] KOG2650 Zinc carboxypeptidase
Length = 429
Score = 154 bits (388), Expect = 3e-37
Identities = 97/320 (30%), Positives = 161/320 (50%), Gaps = 21/320 (6%)
Query: 121 ESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEK 180
ES + + + L TIY WLD + +P+ VTV G + +G +K + +++N
Sbjct: 117 ESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKLTSN---- 172
Query: 181 NPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDG 240
+ K I I G+HAREW+S + Y I QLLT + + +++I P NPDG
Sbjct: 173 -ANNKAIFIESGIHAREWISPAAATYIINQLLT--SQDPKVQQLAQDYNWIIFPCVNPDG 229
Query: 241 YVYTWTHDRLWRKNRQQTYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALE 298
Y YT+ HDR+WRKNRQ F C G+D++ ++ W TGS+ P ++G S LE
Sbjct: 230 YKYTFEHDRMWRKNRQ--LFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELE 287
Query: 299 AESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIR 358
+ +++ + I Y+ HSY+Q +++PYGY+ + + + ++L E S AI+
Sbjct: 288 TKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERV-SNYDDLQEFGKKASAAIK 346
Query: 359 RKSGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAY---WAFQLKLRDTGNHGFLLP 415
++G+ Y S E + P SG ++D+ + + F+L+ F+LP
Sbjct: 347 AENGRDYVSGSLFE----TIYP--SSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILP 400
Query: 416 PKFIVPVGEEIYAAVQYFCE 435
I P E + A++ E
Sbjct: 401 AVEIQPTASEAFTAIRAIVE 420
>Hs17447410 [S] KOG2650 Zinc carboxypeptidase
Length = 428
Score = 152 bits (383), Expect = 1e-36
Identities = 93/303 (30%), Positives = 159/303 (51%), Gaps = 14/303 (4%)
Query: 130 FDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIII 189
++ Y + IY W+ + + ++VT + G T+E + L IS + NP KK I +
Sbjct: 47 YNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPS--GNP-KKIIWM 103
Query: 190 TGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDR 249
G+HAREW++ + + + ++L + + + + L +LDF ++PV N DGY+YTWT DR
Sbjct: 104 DCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDR 163
Query: 250 LWRKNRQQTYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALEAESWDEYVN 307
LWRK+R CFG D++ +F+ W G++ +++ G P E ++ ++
Sbjct: 164 LWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIE 223
Query: 308 KAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHV 367
K + I +L HSY Q +L PYGY+ + E ++++ + A++ K G Y V
Sbjct: 224 SKKDD--ILCFLTMHSYGQLILTPYGYTKNKSSNHPE-MIQVGQKAANALKAKYGTNYRV 280
Query: 368 LSSCEDRGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPVGEEIY 427
SS + + SGS+ D+ +++ +LRD+G +GF+LP I P EE
Sbjct: 281 GSSADILYA------SSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETM 334
Query: 428 AAV 430
AV
Sbjct: 335 EAV 337
>7297556 [S] KOG2650 Zinc carboxypeptidase
Length = 430
Score = 152 bits (383), Expect = 1e-36
Identities = 117/431 (27%), Positives = 209/431 (48%), Gaps = 55/431 (12%)
Query: 20 TAEARDYSNYKVCRFNDESQFSVIISK-----------LKDIAMIKQEYEFDIWAKSKSH 68
+AE Y NY++ + N E+ + + K L + ++ + + I A K
Sbjct: 21 SAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADIQI-IVAPHKVP 79
Query: 69 GFMDIRMHDDILEQFPSCDIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRPKDI 128
F++I +I + S D+ + L+ + + K A+ G +
Sbjct: 80 DFLEILGKSEIKYELQSRDVQ-KSLDEI--DEKVAIKGRATTAYN--------------- 121
Query: 129 FFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKT-I 187
+ +Y +LD Y WL L + P +VT+ G+T++GR + + I+ N K I
Sbjct: 122 -WAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGI 180
Query: 188 IITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTH 247
+ G+HAREW++ + + I QLLT ++ E ++ + ++P NPDGYVYT T
Sbjct: 181 FLEAGIHAREWIAPAAATFIINQLLTSEVENIKE--LAENYTWYVLPHANPDGYVYTHTT 238
Query: 248 DRLWRKNRQQTYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALEAESWDEY 305
+RLWRK R T + CFG D + ++ F W G++ CS++Y+G S F +E S ++
Sbjct: 239 NRLWRKTR--TPYGSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKF 296
Query: 306 VNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGY 365
+ K + + YL H+Y+Q +LYPYG++ D LP ++ + ++ A+ ++ G Y
Sbjct: 297 IEGLKGKVQL--YLSLHAYSQYLLYPYGHTSD-LPDNVADFEKVFDASIAAVNKRYGTTY 353
Query: 366 HVLSSCEDRGSDLQPGL--GSGSALDYMYHHR-AYWAFQLKLRDTGNH---GFLLPPKFI 419
G ++ + +G+++D+ Y + AF +LR + GF LP + I
Sbjct: 354 --------TGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLPAEQI 405
Query: 420 VPVGEEIYAAV 430
VP EE+ ++
Sbjct: 406 VPASEELLDSI 416
>CE25665 [S] KOG2650 Zinc carboxypeptidase
Length = 581
Score = 151 bits (381), Expect = 2e-36
Identities = 125/466 (26%), Positives = 206/466 (43%), Gaps = 59/466 (12%)
Query: 7 TLWVINLIVLFTNTAEARDYSNYKVCRFNDESQFSVIISKLKDIAMIKQ--------EYE 58
TLW++ LI F AE D + +F V+ + D+ +K +++
Sbjct: 9 TLWLLILISAFAINAEIAD---------DKPPKFQVLRAHATDVPQLKALRDIHERTQHD 59
Query: 59 FDIWAKSKSHGFM-DIRMHDDILEQFPSC--------DIIIEDLNSVISETKSAVGGETS 109
D W G DI + +D +E S D+IIED+ +I E K S
Sbjct: 60 LDFWQTPSKVGHRADIMVDEDRMEWLDSVLKNSNISYDVIIEDVGKLILE-KEHGPPRFS 118
Query: 110 NDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLK 169
N ++ + R + F EY TI W+ ++ +PD V G T EGR ++
Sbjct: 119 NLLFSKRMHNEGGNRAR-YGFGEYHSYQTICDWMKDIERKYPDKAKVFTMGTTSEGRPIQ 177
Query: 170 ALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLD 229
+ I + V +N DK+ I GG+HAREW +V T + I +L+ Y +D L+
Sbjct: 178 GIKIGSQ-VWRN-DKRIFWIDGGIHAREWAAVHTALWFIDRLIADYNDDSLVRAAVDRLN 235
Query: 230 FLIIPVFNPDGYVYTWTH----DRLWRKNRQQTYFPR--------CFGIDIDHSFDFQW- 276
F I+PV NPDGY Y+ + RLWRKNR + C G+D++ ++D+ +
Sbjct: 236 FYILPVANPDGYEYSRSDVSPMIRLWRKNRAGVVCKKDRWFRDRCCGGVDLNRNYDWHFG 295
Query: 277 -TGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYS 335
TGS+ CSE Y G S F E S +++ ++ I ++ H+Y+Q ++PY ++
Sbjct: 296 ETGSSTDKCSEIYQGSSAFSESETRSMRDFLTSSELNGKIDAFITLHTYSQMWIHPYSHA 355
Query: 336 CDALPRDL--------ENLLELSYGLSKAIRRKSGKGYHVLSSCEDRGSDLQPGLGSGSA 387
++P D+ N+ + A+ G Y GSD+ GS
Sbjct: 356 RKSVPADVAELVCVDENNVQRVGRAAVAALENTYGTKYKF-----GTGSDILYPSAGGSD 410
Query: 388 LDYMYHHRAYWAFQLKLRDTGN--HGFLLPPKFIVPVGEEIYAAVQ 431
R + + L+LR + GF+L ++P +E + ++
Sbjct: 411 DWAKGTLRIKYVYLLELRPGEDVWDGFILDQHQLIPTAKETWNGIK 456
>CE28646 [S] KOG2650 Zinc carboxypeptidase
Length = 540
Score = 150 bits (379), Expect = 4e-36
Identities = 127/488 (26%), Positives = 223/488 (45%), Gaps = 78/488 (15%)
Query: 12 NLIVLFTNTAEARDYSNYKVCRFNDESQ--FSVIISKLKDIAMIKQEYEFDIWAKSKS-H 68
+L++ +A + ++ V R +SQ F I K+ +++ + W K H
Sbjct: 6 SLLIFLCFSAVSLSTQSFAVYRLLPKSQTDFQAIQRLYKNAT----DHDLNFWKTGKDKH 61
Query: 69 GFMDIRMHDDILEQFPSCDII-IEDLNSV--ISETKSAVGGETSNDARTQSF---FDAES 122
GF D+ + D+ D + + D++ + I + + + +N + F +D S
Sbjct: 62 GFWDVMV--DMKNSKYFLDFLQVNDISYIKTIDDVEGLITKHENNKTLSNMFPRLWDDSS 119
Query: 123 KRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNP 182
D F Y + W+ L + +P +V G+T EGR++ + I ++
Sbjct: 120 SAHYD--FHTYGSYQRMTDWMKQLVVKYPKMVQYISIGKTTEGRNIDGVEIGGDS----R 173
Query: 183 DKKTIIITGGVHAREWVSVSTVCYTIFQLLT---------------------RYGKSKTE 221
KK I GG+HAREW + T + I Q+ R K K +
Sbjct: 174 TKKIFWIDGGIHAREWAAPHTALFFIHQVCDPAPSEKSVFRLVPLGLHKCWQRQKKGKLD 233
Query: 222 TRFL-------------DHLDFLIIPVFNPDGYVYTWT----HDRLWRKNRQQTYFPR-- 262
++L + + F+++P NPDGY +T + H RLWRKNR + +
Sbjct: 234 NKWLTSRANEPGIKKLLNEITFVVVPCLNPDGYEFTRSSTNPHVRLWRKNRSKMQCRKDI 293
Query: 263 ------CFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYN 314
C G+D++ +FDF + +G++D PCSE Y G SPF EA++ + + + +
Sbjct: 294 WGRNRCCRGVDLNRNFDFHFRESGTSDDPCSEIYQGPSPFSEPEAKAVRDALLSQRYKGR 353
Query: 315 IHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSSCEDR 374
Y+ H+Y+Q ++PYG+ DA P D+++L E+ ++A++R G Y V S +
Sbjct: 354 TDAYITLHTYSQIWIHPYGHKKDAYPGDIKDLYEVGKKAAQALKRVYGTKYVVGSGAD-- 411
Query: 375 GSDLQPGLGSGSALDYMYHH-RAYWAFQLKLR-DTGN-HGFLLPPKFIVPVGEEIYAAVQ 431
L P SG + D+ H + + + L+LR D N GF+L K ++P E + V+
Sbjct: 412 --TLYP--ASGGSEDWAKHEAKVKFVYLLELRPDEKNWDGFILDEKELIPTARETWEGVR 467
Query: 432 YFCEFILN 439
E +L+
Sbjct: 468 VVAEAVLD 475
>CE20027 [S] KOG2650 Zinc carboxypeptidase
Length = 666
Score = 146 bits (368), Expect = 7e-35
Identities = 94/328 (28%), Positives = 151/328 (45%), Gaps = 30/328 (9%)
Query: 130 FDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIII 189
F +Y + ++ ++ +P + + G T EG+ ++ L I + K K+ + +
Sbjct: 134 FGDYASYADMVKYMRTIEFYYPRIAKIVRIGATHEGKPIEGLKIGARSSHK---KRAVWV 190
Query: 190 TGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHD- 248
G +HAREW S T Y I QL++ YGK T ++D LDF I+P NPDGY YT T
Sbjct: 191 DGNIHAREWASSHTALYFINQLVSEYGKDAQITNYVDTLDFYIVPCLNPDGYEYTRTSPI 250
Query: 249 ---RLWRKNRQQTYF--------PRCFGIDIDHSFDFQWT--GSNDFPCSESYSGESPFE 295
RLWRKNR C G+D++ +F F W GS+ PCS Y GE F
Sbjct: 251 PTVRLWRKNRSPELCRPSLWGGEKCCRGVDLNRNFRFHWAERGSSYEPCSNIYHGEEVFS 310
Query: 296 ALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSK 355
E + ++ + + + ++ HSYAQ +YPY + P D+ L + +
Sbjct: 311 EPETRAVRNFLATPEMKDRVDAFVTLHSYAQLWIYPYSHEEQNYPEDIGELRKTARKAIN 370
Query: 356 AIRRKSGKGYHVLSSCEDRGSDLQPGLGSG-----SALDYMYHHRAYWAFQLKLRDTGNH 410
+ R G Y + + + L P G SAL+ Y + Q++L ++
Sbjct: 371 RLSRVYGTNYRMGTGAD----TLSPAAGGSDDWAKSALNVKYVYLIELRPQMEL----SN 422
Query: 411 GFLLPPKFIVPVGEEIYAAVQYFCEFIL 438
GF+L K ++P E + + + +L
Sbjct: 423 GFILHKKELIPTAVETFEGFREVVDAVL 450
>7295241 [S] KOG2650 Zinc carboxypeptidase
Length = 344
Score = 146 bits (368), Expect = 7e-35
Identities = 86/222 (38%), Positives = 121/222 (53%), Gaps = 11/222 (4%)
Query: 139 IYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREW 198
I +LD L FP V V+ G ++E R LK L I+ + +N K I+I G VHAREW
Sbjct: 50 INDYLDSLLERFPKRVQVKQFGWSYERRPLKVLTITNGDGRRN--KPVILIDGTVHAREW 107
Query: 199 VSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQT 258
+S S Y I QLL YG ++ L D++I+PV N DGY YT T R WRK+R+ T
Sbjct: 108 ISPSMALYIIQQLLDNYGDNQ---ELLQDYDWVIMPVVNADGYEYTHTDSRYWRKSRRPT 164
Query: 259 YFPRCFGIDIDHSFDFQW---TGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNI 315
P C G DI+ +F ++W GS+ PC Y GE PF+ E++ + + K N
Sbjct: 165 SNPECIGTDINRNFGYEWGHDEGSSSDPCENIYRGERPFDQSESQVLRDVMLHYKGRLNF 224
Query: 316 HGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAI 357
YL HSY L P+GY+ D P ++++ ++ +KAI
Sbjct: 225 --YLSLHSYGNYFLLPWGYTSD-FPDTYQDMMSVADAGAKAI 263
>CE09182 [S] KOG2650 Zinc carboxypeptidase
Length = 323
Score = 145 bits (367), Expect = 9e-35
Identities = 87/293 (29%), Positives = 150/293 (50%), Gaps = 19/293 (6%)
Query: 142 WLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSV 201
+L+ L +P+ V ++ G ++EGR + A+ I+ + K + I G+HAREW+S
Sbjct: 3 FLNSLAQQYPNDVKLQNIGNSYEGRSITAVRIA----DDGSSKPIVWIDAGIHAREWISY 58
Query: 202 STVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFP 261
+ Y I+ ++++ LD + +++P NPDGY Y+ T+DR+WRK R +
Sbjct: 59 NVALYLIYTIVSQ----PAYRNLLDSVQLVVVPNTNPDGYEYSRTNDRMWRKTRSRFTNS 114
Query: 262 RCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYL 319
RC G D + ++ F W G + CSE + G P E + + + E I GY+
Sbjct: 115 RCAGADANRNYPFYWGTQGVSHSQCSEIFCGSRPQSEPEVLALTNAI--IRDEERIKGYI 172
Query: 320 DFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSSCEDRGSDLQ 379
HSY QE+LYP+G++ P D+++L+++ ++ AIR + Y V++S G L
Sbjct: 173 ALHSYGQEILYPWGHTQRTYPTDVQDLIQVGRAMASAIRAVNNTDYTVVNS----GDGLY 228
Query: 380 PGLGSGSALDYMYHHRAYWAFQLKLRDTGNH-GFLLPPKFIVPVGEEIYAAVQ 431
P G+ D+ +++ ++L + GF LP I V E + A+Q
Sbjct: 229 PAAGASD--DWAKSRGIKYSYTIELSPIDDFTGFSLPEDRINQVCREAFQAIQ 279
>7300993 [S] KOG2650 Zinc carboxypeptidase
Length = 467
Score = 143 bits (361), Expect = 4e-34
Identities = 91/316 (28%), Positives = 158/316 (49%), Gaps = 21/316 (6%)
Query: 121 ESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEK 180
E +P++ + Y L++I WL L + P+++ VE G + +GR + + I+ +N
Sbjct: 155 EDTKPEEFDWKRYHPLESINAWLKKLAETHPEVLLVE-LGVSAQGRPILGVQIAFDN--- 210
Query: 181 NPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDG 240
++ T+ + G+HAREW++ +T Y I QL+ K + I P NPDG
Sbjct: 211 -ENRTTVFVESGIHAREWIAPATATYIIDQLVN--SKDSAVQALARSQRWYIFPTVNPDG 267
Query: 241 YVYTWTHDRLWRKNRQQTYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALE 298
Y YT+ DR+WRKNR F C G+D++ +F F W TG++ PC YSG S +E
Sbjct: 268 YQYTFKGDRMWRKNR--ALFGICRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASEVE 325
Query: 299 AESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIR 358
+ E++ I ++ HSY+Q +++PYG+S + + + +L ++ + I+
Sbjct: 326 TQRMIEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVD-NYHDLTDIGKLAANKIK 384
Query: 359 RKSGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAY---WAFQLKLRDTGNHGFLLP 415
SG+ Y S E + P SG + D+ + ++++L+ F+L
Sbjct: 385 DVSGRIYKSGSIYE----TIYP--SSGGSKDWAHGQLKIPITFSYELRGPADSEDLFILS 438
Query: 416 PKFIVPVGEEIYAAVQ 431
K I P E +A++Q
Sbjct: 439 AKEIEPTAAEAFASIQ 454
>CE24363 [S] KOG2650 Zinc carboxypeptidase
Length = 545
Score = 143 bits (360), Expect = 6e-34
Identities = 91/329 (27%), Positives = 157/329 (47%), Gaps = 29/329 (8%)
Query: 60 DIW-AKSKSHGFMDIRMHDDILEQFP--------SCDIIIEDLNSVISETKSAVGGETSN 110
D W A S +G +DI + + +QF + + I+DL+ ++ E + + +++
Sbjct: 59 DFWHAPSVVNGTVDIMVAPEHTDQFRQYLEKHGYTFQVAIDDLHKLLIEKEGNLSTHSND 118
Query: 111 DARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKA 170
DA + + EY + TWL+ + + PD+ + G T EGRD+
Sbjct: 119 DAFFLKRLHDDVGFHSRLRMGEYYSYSVLSTWLERIAENMPDIAKLIKVGTTIEGRDILG 178
Query: 171 LHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDF 230
L + PDKK ++I G+HAREW ++ T Y I ++ + +LD++
Sbjct: 179 LKFGKDT----PDKKIVVIDAGIHAREWAAIHTASYFINLIVNGREEDPQIQNYLDNIVL 234
Query: 231 LIIPVFNPDGYVYTWT-----HDRLWRKNRQQ-------TYFPRCFGIDIDHSFDFQWT- 277
IIPV NPDGY YT T R+WRK+R C G+D++ +FDF+++
Sbjct: 235 YIIPVLNPDGYEYTRTDKTNPRARMWRKSRSPKACAFDGVRNSCCMGVDLNRNFDFRFSE 294
Query: 278 -GSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSC 336
G++ +PCSE Y G S F E++++ +++ K + Y+ HSY+Q +Y Y +
Sbjct: 295 IGASRYPCSEIYHGPSAFSEPESKAYSQFLTSLKG--RLEAYITLHSYSQLWIYSYSHRK 352
Query: 337 DALPRDLENLLELSYGLSKAIRRKSGKGY 365
D+E ++ + + R G Y
Sbjct: 353 FTYAPDIEETRRVAAKAVQELGRMYGTKY 381
>CE20329 [S] KOG2650 Zinc carboxypeptidase
Length = 455
Score = 139 bits (349), Expect = 1e-32
Identities = 119/433 (27%), Positives = 203/433 (46%), Gaps = 51/433 (11%)
Query: 19 NTAEAR-DYSNYKVCRFNDESQFSVIISKLK--DIAMIKQEYE----FDIWAK-SKSHGF 70
N+ E R DYS Y + RF ++ S + KL+ D+ + K DIWA+ SK + +
Sbjct: 23 NSGEKRADYSGYTLHRFKVDTS-SDTMEKLEGYDMQLDKTTQTARLLIDIWAEPSKQNPY 81
Query: 71 MDIRMHDDILEQFPSC--DIIIEDLNSVISETKSAVGGETS----NDARTQSFFDAESKR 124
DI + + L++F S + L + + +S + E N R + K
Sbjct: 82 ADILVAPEFLQKFKSLLTSAELSTLKMLEGDIQSQINAERHAMIRNSVRRRK---RAMKT 138
Query: 125 PKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDK 184
++ + Y + + ++ LL D+V + +H + P+K
Sbjct: 139 WQEFDTNAYHSYNEMVEFMKLLSEQKSDMVEM--------------IHPPGPSP---PEK 181
Query: 185 KTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYT 244
+II+ GVHAREW++ + + I +++ YG++ T L D+ I+P NPDGY Y+
Sbjct: 182 PSIIVDAGVHAREWIAPAVGLFMIRKIVEEYGRNPQVTANLQKFDWYIMPQVNPDGYEYS 241
Query: 245 WTHDRLWRKNRQQ--TYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALEAE 300
T DRLWRK R + T C G D + ++ ++W G+N PCS Y G P+ E
Sbjct: 242 RTTDRLWRKTRSKNVTVNRWCVGADANRNWGYRWGEAGANRTPCSNIYMGSHPYSEPEIR 301
Query: 301 SWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRK 360
E+ + N Y+ HSY Q +L P+GY+ + + ++ + ++AI+
Sbjct: 302 GLKEFFTWQIT--NPMVYISLHSYGQLLLSPWGYT-NERTENYQDQQNAAKEAAQAIKNT 358
Query: 361 SGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTGN---HGFLLPPK 417
+G Y + E + P SG+++D+M H + + ++LR T N F LPP
Sbjct: 359 TGVSYSYGTISE----MMYP--ASGTSIDFMQHRGVPYIYGVELRPTDNPNSFAFNLPPS 412
Query: 418 FIVPVGEEIYAAV 430
+I G+E+ AA+
Sbjct: 413 YIRATGDEMLAAL 425
>7295238 [S] KOG2650 Zinc carboxypeptidase
Length = 354
Score = 138 bits (348), Expect = 1e-32
Identities = 84/278 (30%), Positives = 144/278 (51%), Gaps = 12/278 (4%)
Query: 95 SVISETKSAVGGETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLV 154
SVI+E + ++ + Q + S + + F + I +LD L ++P V
Sbjct: 22 SVINENFGESLRQERDENQNQRLMNLRSAE-RSVSFKAFHRHAEINAYLDELAAAYPSRV 80
Query: 155 TVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTR 214
+V+ G+++E RD+K + I+ N + K + + G+HAREW++ + Y I QL+
Sbjct: 81 SVQVAGKSYENRDIKTITIT--NGDGKTGKNVVFLDAGIHAREWIAHAGALYVIHQLVEN 138
Query: 215 YGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGIDIDHSFDF 274
+ + + L D++I+PV NPDGY Y+ T R+WRK R + C+G D + +FDF
Sbjct: 139 FAAN---SELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTR-KPISSACYGTDANRNFDF 194
Query: 275 QW--TGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPY 332
W G++ + CS+++ GE+ F E + + + YL HSY +LYP+
Sbjct: 195 HWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKF--YLTLHSYGNYLLYPW 252
Query: 333 GYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSS 370
G++ ALP + E++ G + AI+ +G Y V SS
Sbjct: 253 GWT-SALPSSWRDNDEVAQGGADAIKSATGTKYTVGSS 289
>7295316 [S] KOG2650 Zinc carboxypeptidase
Length = 312
Score = 134 bits (338), Expect = 2e-31
Identities = 97/332 (29%), Positives = 163/332 (48%), Gaps = 40/332 (12%)
Query: 8 LWVINLIVLFTNTAEARDYSNYKV--CRFNDESQFSVIISKLKDIAMIKQEYEFDIWAKS 65
L V+ L L + + R Y NYKV R +D QF ++ ++ + + + W ++
Sbjct: 6 LLVVGLFGLARSVEQVR-YDNYKVYNVRIDDLEQFKLLHTQERSLKLSS-------WREA 57
Query: 66 KSHG-FMDIRMHDDILEQFPSCDIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKR 124
+ G DI + + + F S++++ + N Q+ DA+ R
Sbjct: 58 RHLGESSDIMLPPEYQKTF----------ESLLTKHNFTYNLKIDN---VQTHIDAQ--R 102
Query: 125 PKD----IFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEK 180
PK + + ++ L+ IY WLD+++ +PD+VT G ++EGR ++ + IS E
Sbjct: 103 PKQRITSMEWTQFHTLEEIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYK--EG 160
Query: 181 NPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDG 240
NP + I +HAREW++ +T+ Y I +LL ++ ++D+ IIPV N DG
Sbjct: 161 NP---AVFIESNIHAREWITSATITYFIDELLV--PRNPAVRDIAQNVDWYIIPVLNTDG 215
Query: 241 YVYTWTHDRLWRKNR-QQTYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEAL 297
+ Y+ +RLWRK+R C G D++ +FD+ W TG+ PCS+ Y+G SP
Sbjct: 216 FAYSHEVERLWRKSRLPSDPTGECIGTDLNRNFDYLWMLTGAESDPCSQLYAGPSPESDP 275
Query: 298 EAESWDEYVNKAKSEYNIHGYLDFHSYAQEVL 329
E Y+N + E I Y+ HSY + L
Sbjct: 276 EISQLTAYINNSIPEGTIKIYISLHSYGHQGL 307
>7295242 [S] KOG2650 Zinc carboxypeptidase
Length = 415
Score = 134 bits (338), Expect = 2e-31
Identities = 94/317 (29%), Positives = 150/317 (46%), Gaps = 22/317 (6%)
Query: 129 FFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTII 188
FF Y + +++ L +P E G++ EGR + AL IS N+ + ++
Sbjct: 117 FFSHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNSRVR--PRRVAY 174
Query: 189 ITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHD 248
I H REW++ TV Y ++LL+ + TR L ++ ++P+ NPDGY YT T D
Sbjct: 175 IQAATHGREWITTQTVLYLAYELLSNL---RAFTRVLQDVEIFLVPLVNPDGYEYTHTTD 231
Query: 249 RLWRKNRQQTYFPRCFGIDIDHSFDFQWT--GSNDFPCSESYSGESPFEALEAESWDEYV 306
R WRKNR + C G+DI+ +F W G++ CSE YSG +P E + Y+
Sbjct: 232 RFWRKNRHRYAGHSCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSEPETSAVVRYL 291
Query: 307 NKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYH 366
++ + LD HS+ + + YPYGY+ + +P + L ++ + I R G Y
Sbjct: 292 EFNRNRVKLS--LDVHSFGKFIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYRGTRYT 349
Query: 367 VLSSCEDRGSDLQPGLGSGSALDYMYHHRAY-WAFQLKLRDTGNHGFLLPPKFIVPVGEE 425
+S SGS D+ Y + ++ L+L H +P I+ V +E
Sbjct: 350 TGTSASILYE------ASGSLDDFAYGNLGIPLSYTLELPGDEFH---VPAHDIIHVCKE 400
Query: 426 IYAAVQYFCEFILNPDL 442
+A F EFI + L
Sbjct: 401 TFAG---FIEFIRHVSL 414
>7290632 [S] KOG2650 Zinc carboxypeptidase
Length = 507
Score = 134 bits (338), Expect = 2e-31
Identities = 98/357 (27%), Positives = 165/357 (45%), Gaps = 26/357 (7%)
Query: 85 SCDIIIEDLNSVISETKSAVGG-ETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWL 143
S +I+I+D+ S I E+ V E D+ + + + Y D I +L
Sbjct: 152 SYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWMEVPGSTMNWRRYHDQADIKQFL 211
Query: 144 DLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVST 203
L ++ + V + G T R L+ + +S N PD + + G+ AR+W+S +
Sbjct: 212 QTLLETYSENVELIQIGVTRNKRPLEVIRVSNGN----PDNWAVFVDAGLQARDWLSPAA 267
Query: 204 VCYTIFQLLTRYGKSKTETR-----------FLDHLDFLIIPVFNPDGYVYTWTHDRLWR 252
+ Y I +L +G+ K + + + +D+ +P+ NPDGY Y+ DRLW
Sbjct: 268 LTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQTDRLWT 327
Query: 253 KNRQQTYFPRCFGIDIDHSFDFQW--TGSNDFPCSESYSGESPFEALEAESWDEYVNKAK 310
KNR C+G+++D +FD+ W TGS PC Y G F E+ + +++ +
Sbjct: 328 KNRGYDSVSGCYGVNLDRNFDYGWDGTGSTSNPCKNLYRGAHSFSEPESRAVCSFLSGMR 387
Query: 311 SEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSS 370
EY + Y+ Y Q + YP+G D + + NL + + A+RR + Y S
Sbjct: 388 -EY-LGAYVSLGGYGQAITYPWG-DADYVTENQRNLKQTARRAVLALRRLNQAEYS--SG 442
Query: 371 CEDRGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPVGEEIY 427
R +PG + D + F + L+D G +G+LLPP +IV GEE++
Sbjct: 443 TSYRQKLARPGNSADWVQDRI---GPQLVFNMFLKDQGRYGYLLPPHYIVESGEEVF 496
>7295243 [S] KOG2650 Zinc carboxypeptidase
Length = 504
Score = 134 bits (336), Expect = 4e-31
Identities = 101/344 (29%), Positives = 154/344 (44%), Gaps = 46/344 (13%)
Query: 125 PKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHIS---TNNVEKN 181
P+ Y D + +L L + V V G T E R+++AL I+ + NVE +
Sbjct: 30 PRPDILHTYLDYKQVNQYLQYLAQRYAHFVHVHILGHTHEKREIRALEINWMNSENVELS 89
Query: 182 PD----------------------------KKTIIITGGVHAREWVSVSTVCYTIFQLLT 213
P +KT+ I G HAREW+SVST I+QL
Sbjct: 90 PQMREHSPRLFDIGPNGRFTVPVIHVGEHCRKTVFIEAGTHAREWISVSTALNCIYQLTE 149
Query: 214 RYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGIDIDHSFD 273
RY ++ L L F+I+P+ NPDGY Y+ T + WRKNR+ + G D + ++D
Sbjct: 150 RYTRN---IEVLRKLRFIIVPLVNPDGYEYSRTKNPKWRKNRRPHKSAKFVGTDCNRNYD 206
Query: 274 FQWTGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYG 333
W +Y GESPF E + +++ S N+ +L HSY Q ++YP+G
Sbjct: 207 IFWNSGPSKINRNTYKGESPFSEPETRAMRCILDRMSS--NLLFFLSLHSYGQSIMYPWG 264
Query: 334 YSCDALPRDLENLLELSYGLSKAIRRKSGKGYHVLS-SCEDRGSDLQPGLGSGSALDYMY 392
Y C P L L+ AI+ +G+ Y S SC L +GS +DY+Y
Sbjct: 265 Y-CRDNPIYWRELSSLANSGKSAIKSYNGREYRTGSISC------LTKRTIAGSVVDYVY 317
Query: 393 H-HRAYWAFQLKLRDTGNHGFLLPPKFIVPVGEEIYAAVQYFCE 435
+ A ++L + GF P + I +G E + ++ C+
Sbjct: 318 GVLKVPMALVMEL-PSRELGFQPPVEMISQIGHESWYGIREMCK 360
>7295240 [S] KOG2650 Zinc carboxypeptidase
Length = 424
Score = 132 bits (332), Expect = 1e-30
Identities = 95/314 (30%), Positives = 160/314 (50%), Gaps = 20/314 (6%)
Query: 131 DEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIIT 190
+ Y + I ++D L FP V V+ G ++E R LK + I+ + + N KK I +
Sbjct: 122 ERYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKAN--KKVIFMD 179
Query: 191 GGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHD-- 248
GG HAREW+S + V Y I QL+ ++ + L D++I+P+ N DGY +T T
Sbjct: 180 GGFHAREWISPAAVLYVIDQLVEQF---EENAHLLKDYDWVILPLVNADGYEHTQTGTLA 236
Query: 249 RLWRKNRQ-QTYFPR-CFGIDIDHSFDFQWT--GSNDFPCSESYSGESPFEALEAESWDE 304
R+WRK RQ TY + C+G D + +FDF W G++ PC+++Y+G + F E + +
Sbjct: 237 RMWRKTRQPYTYAGQTCYGADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRD 296
Query: 305 YVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKG 364
++ + YL HSY +LYP+G++ D LP + E+L ++ ++AI +G
Sbjct: 297 LMHSLADRGIM--YLTLHSYGNYLLYPWGWTSD-LPENWEDLDAVARTGAEAIENATGTV 353
Query: 365 YHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPVGE 424
Y SS + +G++ DY Y+ + ++L G+ GF P I
Sbjct: 354 YTYGSSTN------VLYIAAGASDDYGYYAGFNVSITMELPGAGSIGFNPPVTRIDEFVT 407
Query: 425 EIYAAVQYFCEFIL 438
E + ++ E ++
Sbjct: 408 ETWIGIRAMAEKVI 421
>7295239 [S] KOG2650 Zinc carboxypeptidase
Length = 400
Score = 132 bits (331), Expect = 1e-30
Identities = 96/308 (31%), Positives = 154/308 (49%), Gaps = 27/308 (8%)
Query: 131 DEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIIT 190
+ Y + + I +++ L P V ++ G+++EGR LK + I+ + +N K I++
Sbjct: 98 ERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRN--KNVILVD 155
Query: 191 GGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHD-- 248
GG HAREW+S + Y I QL+ Y LD D++I+PV NPDGY YT +
Sbjct: 156 GGFHAREWISPAAATYLINQLV--YNLEDNADLLLD-FDWVILPVVNPDGYEYTQLSEDT 212
Query: 249 RLWRKNRQQTYFPRCFGIDIDHSFDFQWT--GSNDFPCSESYSGESPFEALEA----ESW 302
R+WRK R+ + C G D + +FDF W G++D PC Y+G PF EA +
Sbjct: 213 RMWRKTRKPS-SSDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLI 271
Query: 303 DEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSG 362
YV++ + YL HSY +LYP+G++ A+P E+L E++ AI+ +G
Sbjct: 272 HSYVDRGQM------YLTLHSYGSLILYPWGWTA-AVPDTEEDLHEVAAAGQSAIQEATG 324
Query: 363 KGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTGNHGFLLPPKFIVPV 422
Y + S SG++ DY ++ +F ++L G GF P I +
Sbjct: 325 TIYKIGPSATTINY-----AASGASDDYAFNAGFPISFTMEL-PFGGTGFDPPASDIDSI 378
Query: 423 GEEIYAAV 430
+E + +
Sbjct: 379 VKETWVGI 386
>7293312 [S] KOG2650 Zinc carboxypeptidase
Length = 1430
Score = 130 bits (327), Expect = 4e-30
Identities = 104/462 (22%), Positives = 199/462 (42%), Gaps = 62/462 (13%)
Query: 26 YSNYKVCRFN--DESQFSVIISKLKDIAMIKQEYEFDIWAKSKS-HGFMDIRMHDDILEQ 82
Y Y++ R DE Q + K +K + W K S G D+ + +L
Sbjct: 981 YDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQ-----WLKGPSLRGLTDVLVPPKMLVD 1035
Query: 83 FPSCDIIIEDL--NSVISETKSAVGGETSNDARTQSFFDAESK--RPKDIFFDEYRDLDT 138
F + E + +I + A+ E + + Q+ ++ + P + ++ Y + D
Sbjct: 1036 FQGT-LNYEGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDE 1094
Query: 139 IYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVE-----------KNPDKK-- 185
I +L+ +++ P LV + G++FEGR L + I + K P +K
Sbjct: 1095 IVKYLETVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRK 1154
Query: 186 -----TIIITGGVHAREWVSVSTVCYTIFQLLT--RYGKSKTETRFLDHLDFLIIPVFNP 238
+ + G W+ + + I +LL + KS + F+ + + I+PV NP
Sbjct: 1155 SGQANAVFVEAGAQGLAWIGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPVLNP 1214
Query: 239 DGYVYTWTHDRLWRKNRQQTYFPR---------------------CFGIDIDHSFDFQW- 276
DGY Y+ +DR W+K+R Q P C+G+D+D ++ + W
Sbjct: 1215 DGYAYSHEYDRFWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWG 1274
Query: 277 -TGSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYS 335
GS+ PC+E Y+G +PF E ++ E++ +++ + Y+ +Y Q + YP +
Sbjct: 1275 KRGSSKAPCNEFYAGPAPFSEPETKAVSEFLMDYRTQIKL--YISLQAYGQVISYPVKAN 1332
Query: 336 CDALPRDLENLLELSYGLSKAIRRKSGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHHR 395
L++ L+++ + +R+K K + + + D ++ G A Y
Sbjct: 1333 STFNSERLDDFLDVAMVGTDGLRKKGSKSRYKVDASNDL---IEQRSGCADAF-AAYEIG 1388
Query: 396 AYWAFQLKLRDTGNHGFLLPPKFIVPVGEEIYAAVQYFCEFI 437
+++ L+L D G HG+LLP I P + + + ++I
Sbjct: 1389 IPFSYTLQLADNGVHGYLLPSSAIEPTARDAFEIISGMLDYI 1430
>7295225 [S] KOG2650 Zinc carboxypeptidase
Length = 385
Score = 115 bits (289), Expect = 1e-25
Identities = 84/312 (26%), Positives = 144/312 (45%), Gaps = 20/312 (6%)
Query: 131 DEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIIT 190
D Y D I +LD L LS + VT++ +T+E R LK I+ N + P K+ I +
Sbjct: 36 DNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIIT--NGDGRPGKRVIFLD 93
Query: 191 GGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRL 250
+H+REW++ + TI +L+ + ++ L D+ I+P+ NPDGY Y+ +R
Sbjct: 94 AALHSREWMTPAAALLTIHKLVVEFAENSD---LLTDYDWHIMPLANPDGYEYSRNTERY 150
Query: 251 WRKNRQQTYFPRCFGIDIDHSFDFQW-TGSNDF--PCSESYSGESPFEALEAESWDEYVN 307
WR R CFG +++ +F W G + PC E+Y+G SPF +EA + + ++
Sbjct: 151 WRNTRTPN-GGNCFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIMH 209
Query: 308 KAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIRRKSGKGYHV 367
YL H+ + V YP+ Y D + E+ E+ ++ I + +G
Sbjct: 210 GLVESKRAVMYLSLHTANRSVFYPWVYDTDPVSNQKEH-DEIGRFVADRILQSTGTFIKT 268
Query: 368 LSSCEDRGSDLQPGLGSGSALDYMYHHRAYWAFQLKLRDTG----NHGFLLPPKFIVPVG 423
+ G G+++DY +F ++ TG + F P + I +
Sbjct: 269 WQYAK------YAGTFGGTSMDYALLAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLA 322
Query: 424 EEIYAAVQYFCE 435
EE + ++ F E
Sbjct: 323 EESWTGIKAFAE 334
>CE26965 [S] KOG2650 Zinc carboxypeptidase
Length = 291
Score = 109 bits (272), Expect = 9e-24
Identities = 70/221 (31%), Positives = 112/221 (50%), Gaps = 23/221 (10%)
Query: 56 EYEFDIWAKSKSHGF-MDIRMHDDILEQFPS--------CDIIIEDLNSVISETKSAVGG 106
+ + D W G + + + D+ +QF ++I+D+ VI E K
Sbjct: 44 DVKLDFWKSPSEAGKEVHVMISDEKTQQFMKELDDHSIKHSVMIDDVQKVIVEQK----- 98
Query: 107 ETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGR 166
E + R Q ++ +Y + +L+ L +++P+LV+V+ G T EGR
Sbjct: 99 EKRDKLRKQVRLHDWREQKVQFNLAQYHSFADVINYLNSLAITYPELVSVQPIGTTHEGR 158
Query: 167 DLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLD 226
+ + I+ N K+ I + GG+HAREWVS STV Y I QL+T+Y K +F+D
Sbjct: 159 QIPLIKIT--NKRNGGTKRGIWVDGGIHAREWVSPSTVLYFIHQLVTQYDKDVQIKQFVD 216
Query: 227 HLDFLIIPVFNPDGYVYTWTHD----RLWRKNRQQTYFPRC 263
L++ I+P+ NPDGY Y+ + + RLWRKNR P+C
Sbjct: 217 QLEWYIVPLLNPDGYEYSRSSNDPEIRLWRKNRSP---PKC 254
>CE06536 [S] KOG2650 Zinc carboxypeptidase
Length = 373
Score = 108 bits (269), Expect = 2e-23
Identities = 81/327 (24%), Positives = 149/327 (44%), Gaps = 34/327 (10%)
Query: 129 FFD--EYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKT 186
FFD Y D ++ + P V ++ G+T EGR L + I + P K+
Sbjct: 22 FFDLTVYNDWPQFEDYIKGVAHDNPSFVQLKTIGRTREGRPLLGVRIGKPAL---PGKRK 78
Query: 187 III--TGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYT 244
I + GG HAREW + Y I +L+ Y T++++ LD + PV NPDG+VY+
Sbjct: 79 IAVWLDGGNHAREWPAFHVAVYFIEKLVNGYLSDDKITKYVETLDIYVFPVLNPDGFVYS 138
Query: 245 WTHDRL----WRKNRQ----------QTYFPRCFGIDIDHSFDFQWTGSN---DFPCSES 287
T R WRKNR QT C G+D++ ++D ++ N + PCS+
Sbjct: 139 RTSTRAMIRQWRKNRAPENCTGTGPFQTDI-CCEGVDLNRNYDIGFSHKNYPFNNPCSDE 197
Query: 288 YSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCDALPRDLENLL 347
+ G PF E + +++ ++ ++ + H++ Q + PY Y P+D+++L
Sbjct: 198 FQGPRPFSEPETRAVRDFIMSSEIYGRLYALVSMHTHGQLWILPYNYQKRTYPQDIKDLE 257
Query: 348 ELSYGLSKAIRRKSGKGYHVLSSCEDRGSDLQPGLGSGSALDYMYHH---RAYWAFQLKL 404
L+ + + Y V ++ + G +G A D++ + + + +L
Sbjct: 258 ILANRAADRVFAYRETKYRVGTAAD------MLGTATGGATDWIKKNTPTKYVYVLELPP 311
Query: 405 RDTGNHGFLLPPKFIVPVGEEIYAAVQ 431
F + P +++P+G+E + ++
Sbjct: 312 DMKTWFAFQVKPHWLIPIGKETWLGIE 338
>Hs9966831 [S] KOG2650 Zinc carboxypeptidase
Length = 315
Score = 100 bits (249), Expect = 4e-21
Identities = 56/191 (29%), Positives = 97/191 (50%), Gaps = 17/191 (8%)
Query: 88 IIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQ 147
++IEDL + + S T + R+ S ++ ++ Y L+ I W+ L
Sbjct: 107 VLIEDLQKTLEKGSSL---HTQRNRRSLSGYN----------YEVYHSLEEIQNWMHHLN 153
Query: 148 LSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYT 207
+ L+ + G+++EGR L L + ++ K+ + I G+HAREW+ + +
Sbjct: 154 KTHSGLIHMFSIGRSYEGRCLFILKLG----RRSRLKRAVWIDCGIHAREWIGPAFCQWF 209
Query: 208 IFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGID 267
+ + L Y + L+HL F I+PVFN DGY ++WT+DR WRK R + RC G+D
Sbjct: 210 VKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVD 269
Query: 268 IDHSFDFQWTG 278
+ ++ +W G
Sbjct: 270 ANRNWKVKWCG 280
>Hs16915928 [S] KOG2650 Zinc carboxypeptidase
Length = 360
Score = 90.1 bits (222), Expect = 6e-18
Identities = 70/276 (25%), Positives = 122/276 (43%), Gaps = 64/276 (23%)
Query: 86 CDIIIEDLNSVISETKSAVGGETSNDARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDL 145
C +++ D+ +I + + SND S R ++++Y L+ IY+W++
Sbjct: 91 CSVLLADVEDLIQQ-------QISNDT--------VSPRASASYYEQYHSLNEIYSWIEF 135
Query: 146 LQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVC 205
+ PD++T G +FE L L +S ++ K I I G+HAREW+S +
Sbjct: 136 ITERHPDMLTKIHIGSSFEKYPLYVLKVSG---KEQAAKNAIWIDCGIHAREWISPAFCL 192
Query: 206 YTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFG 265
+ I H+R+WRKNR C G
Sbjct: 193 WFI-------------------------------------GHNRMWRKNRSFYANNHCIG 215
Query: 266 IDIDHSFDFQ-WT--GSNDFPCSESYSGESPFEALEAESWDEYVNKAKSEYNIHGYLDFH 322
D++ +F + W G++ CSE+Y G P E ++ ++ + ++ I Y+ H
Sbjct: 216 TDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQ--IKAYISMH 273
Query: 323 SYAQEVLYPYGYSCDALPRDLENLLELSYGLSKAIR 358
SY+Q +++PY Y+ + +D E ELS S+A+R
Sbjct: 274 SYSQHIVFPYSYT-RSKSKDHE---ELSLVASEAVR 305
>CE28480 [R] KOG2649 Zinc carboxypeptidase
Length = 1013
Score = 62.8 bits (151), Expect = 1e-09
Identities = 70/295 (23%), Positives = 119/295 (39%), Gaps = 34/295 (11%)
Query: 112 ARTQSFFDAESKRPKDIFFDEYRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKAL 171
A+ F + S + K+ ++E + WL +L++P++ + G++ EGR+L L
Sbjct: 63 AKIGDFINVNSTKLKNHNYNE------MTAWLKATRLNYPNITHLYSAGKSVEGRELWVL 116
Query: 172 HISTNNVEKNPDKKTIIITGGVHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFL 231
IS E + + I G +H E V V Y L YGK+K T +++
Sbjct: 117 IISDKPKEHKLMEPELKIVGNMHGNEVVGREAVLYLAEILCLNYGKNKYLTDLVNNARIH 176
Query: 232 IIPVFNPDGYVYTWTHDRLWRKNRQQTYFPRCFGIDIDHSFDFQWTGSNDFPCSESYSGE 291
++P NPDGY + DR+ R +D++ +F F SG
Sbjct: 177 LMPSMNPDGYEKGFPGDRISAMGRANAN-----DVDLNRNF------PTKFESHRETSGG 225
Query: 292 SPFEALEAESWDEYVNKAKSEYNIHGYLDFHSYAQEVLYPYGYSCD------ALPRDLEN 345
S E E + V K Y + H + YPY S D +
Sbjct: 226 S-----EPEKENIAVMKWLQAYPFVLSTNLHGGSLVANYPYDDSVTGQDGIYTASADDKL 280
Query: 346 LLELSYGLSKAIRR--KSGKGYHVLSSCEDRGSDLQPGLG----SGSALDYMYHH 394
+ELSY ++A + K+G+ + + ++ + + G G +G D+ Y H
Sbjct: 281 FVELSYRYARAHTKMWKTGRRCGLSADGDNFINGITNGAGWYHLAGGMQDWQYEH 335
>7293271 [R] KOG2649 Zinc carboxypeptidase
Length = 518
Score = 53.1 bits (126), Expect = 8e-07
Identities = 29/109 (26%), Positives = 50/109 (45%)
Query: 133 YRDLDTIYTWLDLLQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGG 192
Y D + + +L +P+L + G++ +GRDL + +S++ E K + G
Sbjct: 72 YHDHEELTRFLRATSARYPNLTALYSIGKSIQGRDLWVMVVSSSPYEHMVGKPDVKYVGN 131
Query: 193 VHAREWVSVSTVCYTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGY 241
+H E V + + I +T Y + LD+ I+P NPDGY
Sbjct: 132 IHGNEPVGREMLLHLIQYFVTSYNTDQYVKWLLDNTRIHILPTMNPDGY 180
>7290047 [R] KOG2649 Zinc carboxypeptidase
Length = 1412
Score = 50.4 bits (119), Expect = 5e-06
Identities = 27/96 (28%), Positives = 46/96 (47%)
Query: 146 LQLSFPDLVTVEWTGQTFEGRDLKALHISTNNVEKNPDKKTIIITGGVHAREWVSVSTVC 205
L+ ++P+ V + G++ EGR+L AL IS N +N + +H E V +
Sbjct: 53 LEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIANMHGDETVGRQLLV 112
Query: 206 YTIFQLLTRYGKSKTETRFLDHLDFLIIPVFNPDGY 241
Y LL + + + ++ D ++P NPDGY
Sbjct: 113 YMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGY 148
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.139 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,886,800
Number of Sequences: 60738
Number of extensions: 1302190
Number of successful extensions: 2948
Number of sequences better than 1.0e-05: 43
Number of HSP's better than 0.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2756
Number of HSP's gapped (non-prelim): 48
length of query: 442
length of database: 30,389,216
effective HSP length: 109
effective length of query: 333
effective length of database: 23,768,774
effective search space: 7915001742
effective search space used: 7915001742
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)