ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI7419 good E KOG2964 Amino acid transport and metabolism Arginase family protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI7419 2586722 2587951 410
(410 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPBC8E4.03 [E] KOG2964 Arginase family protein 370 e-102
SPAC11D3.09 [E] KOG2964 Arginase family protein 297 2e-80
SPAPB24D3.03 [E] KOG2964 Arginase family protein 291 2e-78
Hs13376095 [E] KOG2964 Arginase family protein 137 2e-32
At4g08900 [E] KOG2964 Arginase family protein 91 3e-18
At4g08870 [E] KOG2964 Arginase family protein 85 2e-16
Hs10947139 [E] KOG2965 Arginase 73 9e-13
Hs4502215 [E] KOG2965 Arginase 69 1e-11
CE07525_1 [E] KOG2965 Arginase 54 3e-07
>SPBC8E4.03 [E] KOG2964 Arginase family protein
Length = 413
Score = 370 bits (951), Expect = e-102
Identities = 186/349 (53%), Positives = 245/349 (69%), Gaps = 17/349 (4%)
Query: 30 TEMWGEDWPFSGIQTFAHLPHHKCLIDMEKKFDIGVIGVPFDTAVSFRGGARFGPQAIRK 89
++ W D+ +SGI TFAHLPH +CL++ + FDI +IGVPFDTAVS R GARFGP+ IR
Sbjct: 58 SKRWEFDYQYSGISTFAHLPHVRCLVEQSEDFDIAIIGVPFDTAVSHRPGARFGPKGIRS 117
Query: 90 ASQRQTSMRGFNFRADINPYQDWASVVDCGDVPVTPMDNCLALKMMTAAYENLLSHESQT 149
AS RQ ++RGFN ++NPY+ WA ++DCGD+PV+ DN LA++ MT Y +LLS ++
Sbjct: 118 ASSRQMAIRGFNPSLNVNPYESWAKILDCGDIPVSSYDNQLAVRQMTEGYIDLLSRKATA 177
Query: 150 S--DNNLP-----------PRFVTLGGDHSIILPALRALRKTYGRLAVIHFDSHLDTWAP 196
S NNL PR +TLGGDHSI L +LRAL YG ++VIHFDSHLDTW P
Sbjct: 178 SPASNNLKTAGLAKDGIFHPRLITLGGDHSIGLASLRALGHFYGNVSVIHFDSHLDTWNP 237
Query: 197 SK-YPSFWHSDTSEFTHGSMLWIAHNEGLLTENNNIHAGLRTRLSGSSFEDYDDDDKVGF 255
+ YPS+WHSD ++FTHG+M W+A EGL+ +IHAGLRTRLSG+ + DY++D++VGF
Sbjct: 238 KRYYPSYWHSDRADFTHGTMFWMASKEGLINNGTSIHAGLRTRLSGTDYYDYEEDNRVGF 297
Query: 256 HRIEADEIMDGGXXXXXXXXXXXXXXDVPVYISVDIDVLDPSAAPGTGTMEVGGWMTREL 315
IEA EI + G D VY+S+DIDV+DP APGTGT E GGW TRE+
Sbjct: 298 TFIEAQEIDEIG-VNGIVERIKQVVGDTLVYLSIDIDVVDPGLAPGTGTPETGGWTTREM 356
Query: 316 IRIIRELE-DLNLVGADIVEVSPPFDP-TEITSLAGAQIAYELITNMVK 362
I+R+L+ LNLVGA++VEVSPP+D E TSLA + +E++++MVK
Sbjct: 357 KSILRKLDGHLNLVGAEVVEVSPPYDDRAESTSLAASDFIFEILSSMVK 405
>SPAC11D3.09 [E] KOG2964 Arginase family protein
Length = 394
Score = 297 bits (761), Expect = 2e-80
Identities = 159/374 (42%), Positives = 220/374 (58%), Gaps = 22/374 (5%)
Query: 7 ILGALIQFSLTEGHVEQNENANLTEMWGEDWP----------FSGIQTFAHLPHHKCLID 56
+L Q + + + AN E + + +P FSGI TF LP+ KCL D
Sbjct: 10 LLAGAAQLAQAHPKIFEQSRANAVETFDDAFPGDGETQADSVFSGIATFGRLPYWKCLND 69
Query: 57 MEKKFDIGVIGVPFDTAVSFRGGARFGPQAIRKASQRQTSMRGFNFRADINPYQDWASVV 116
+ FDI +G PFDT S+R GARFGP IR+ S+R G+N + NP+ +WA +V
Sbjct: 70 KSQSFDIAFLGAPFDTGTSYRPGARFGPSGIREGSRRLNLYGGYNVPMETNPFNNWAKIV 129
Query: 117 DCGDVPVTPMDNCLALKMMTAAYENLLSH--------ESQTSDNNLPPRFVTLGGDHSII 168
DCGD+P+T DN +A+K + + LL+ + D ++ PR +TLGGDH+I+
Sbjct: 130 DCGDIPLTSYDNAVAIKQIENGHFELLTRKPTSYSEKDGYALDGSVLPRVITLGGDHTIV 189
Query: 169 LPALRALRKTYGRLAVIHFDSHLDTWAPSKYPSFWHSDTSEFTHGSMLWIAHNEGLLTEN 228
LP LR++ + YG +++IHFDSHLD+W P + S HG+ + A EGL++ +
Sbjct: 190 LPILRSVSRAYGPVSIIHFDSHLDSWKPKVFGG-GKSSVGSINHGTYFYHASQEGLVSND 248
Query: 229 NNIHAGLRTRLSGSSFEDYDDDDKVGFHRIEADEIMDGGXXXXXXXXXXXXXXDVPVYIS 288
+NIHAG+RT LSG S DYD+D GF IEA EI D D Y+S
Sbjct: 249 SNIHAGIRTTLSGLS--DYDNDADCGFEIIEAREI-DTIGIDAIIKRIRDRVGDGIAYLS 305
Query: 289 VDIDVLDPSAAPGTGTMEVGGWMTRELIRIIRELEDLNLVGADIVEVSPPFDPTEITSLA 348
+DIDVLDP+ AP TGT E GW TREL I+R L+ + LVGADIVEV+P +D E+T+LA
Sbjct: 306 IDIDVLDPAYAPATGTPESAGWTTRELRTILRGLDGIKLVGADIVEVAPAYDFAEVTTLA 365
Query: 349 GAQIAYELITNMVK 362
A I +E+++ MVK
Sbjct: 366 AADILFEVMSIMVK 379
>SPAPB24D3.03 [E] KOG2964 Arginase family protein
Length = 385
Score = 291 bits (744), Expect = 2e-78
Identities = 155/334 (46%), Positives = 214/334 (63%), Gaps = 15/334 (4%)
Query: 39 FSGIQTFAHLPHHKCLIDMEKKFDIGVIGVPFDTAVSFRGGARFGPQAIRKASQR-QTSM 97
+SGI TF L + +CL + FDI IG+PFDT S+R GARFGP ++R+ S+R T
Sbjct: 40 YSGIATFGRLENVECLSKRSEDFDIAFIGMPFDTGTSYRPGARFGPSSLREGSRRINTKY 99
Query: 98 RGFNFRADINPYQDWASVVDCGDVPVTPMDNCLALKMMTAAYENLLS--------HESQT 149
N +INP++ WA +VDCGD+PVT D A+ + +AY L++ H+
Sbjct: 100 GAVNVPLEINPFKSWAKLVDCGDIPVTTYDILKAMDQLESAYFQLIARKPSSFTDHDGFA 159
Query: 150 SDNNLPPRFVTLGGDHSIILPALRALRKTYGR-LAVIHFDSHLDTWAPSKYPSFWHSDTS 208
++ + PR ++LGGDH+I+LP LRAL + YG+ ++VIHFDSHLDTWAP +D
Sbjct: 160 KNDTVLPRVLSLGGDHTIVLPILRALHRVYGQPISVIHFDSHLDTWAPGLIGDGDEADG- 218
Query: 209 EFTHGSMLWIAHNEGLLTENNNIHAGLRTRLSGSSFEDYDDDDKVGFHRIEADEIMDGGX 268
HGS + A EG+++++ NIHAG+RT +S SF DYDDD GF IEA EI D G
Sbjct: 219 -INHGSYFYFASQEGIMSKDANIHAGIRTPIS--SFSDYDDDVDCGFKIIEAREIDDLGI 275
Query: 269 XXXXXXXXXXXXXDVPVYISVDIDVLDPSAAPGTGTMEVGGWMTRELIRIIRELEDLNLV 328
++ VY+S+DIDVLDP+ AP TGT E GGW +RE+ I+R L+ L V
Sbjct: 276 DGIVKKIRDRVGDNL-VYLSIDIDVLDPAFAPATGTPETGGWSSREMRAILRGLQGLKFV 334
Query: 329 GADIVEVSPPFDPTEITSLAGAQIAYELITNMVK 362
GAD+VEV+P +D EITSLAGAQ+ +++++ MVK
Sbjct: 335 GADLVEVAPAYDVAEITSLAGAQLLFDIVSMMVK 368
>Hs13376095 [E] KOG2964 Arginase family protein
Length = 352
Score = 137 bits (346), Expect = 2e-32
Identities = 98/301 (32%), Positives = 149/301 (48%), Gaps = 24/301 (7%)
Query: 62 DIGVIGVPFDTAVSFRGGARFGPQAIRKASQRQTSMRGFNFRADINPYQDWASVVDCGDV 121
D IGVP DT S R GARFGP+ IR+ S +R N P+Q V D GDV
Sbjct: 72 DAAFIGVPLDTGTSNRPGARFGPRRIREES---VMLRTVNPSTGALPFQS-LMVADLGDV 127
Query: 122 PVTPMDNCLALKMMTAAYENLLSHESQTSDNNLPPRFVTLGGDHSIILPALRALRKTYGR 181
V + + + + A E +++ +P +TLGGDH+I P L+A+ K +G
Sbjct: 128 NVNLYNLQDSCRRIQEACEKIVAAGC------IP---LTLGGDHTITYPILQAMAKKHGP 178
Query: 182 LAVIHFDSHLDTWAPSKYPSFWHSDTSEFTHGSMLWIAHNEGLLTENNNIHAGLRTRLSG 241
+ ++H D+H DT + +H G+ +EGLL + G+R S
Sbjct: 179 VGLLHVDAHTDTTDKALGEKLYH--------GAPFRRCVDEGLLDCKRVVQIGIRG--SS 228
Query: 242 SSFEDYDDDDKVGFHRIEADEIMDGGXXXXXXXXXXXXXXDVPVYISVDIDVLDPSAAPG 301
++ + Y + GF + A++ P+YIS DID LDP+ APG
Sbjct: 229 TTLDPYRYNRSQGFRVVLAEDCWMKSLVPLMGEVRQQMGGK-PIYISFDIDALDPAYAPG 287
Query: 302 TGTMEVGGWMTRELIRIIRELEDLNLVGADIVEVSPPFDPTEITSLAGAQIAYELITNMV 361
TGT E+ G + + IIR + LN++G D+VEVSPP+D + T+L A + +E++ +
Sbjct: 288 TGTPEIAGLTPSQALEIIRGCQGLNVMGCDLVEVSPPYDLSGNTALLAANLLFEMLCALP 347
Query: 362 K 362
K
Sbjct: 348 K 348
>At4g08900 [E] KOG2964 Arginase family protein
Length = 342
Score = 90.9 bits (224), Expect = 3e-18
Identities = 88/320 (27%), Positives = 140/320 (43%), Gaps = 56/320 (17%)
Query: 60 KFDIGVIGVPFDTAVSFRGGARFGPQAIRKA----SQRQTSMRGFNFRADINPYQDWASV 115
K ++GVP SF G F P IR+A S + G + D +
Sbjct: 62 KASTSLLGVPLGHNSSFLQGPAFAPPRIREAIWCGSTNSATEEGKELK-------DPRVL 114
Query: 116 VDCGDVPVTPMDNCLALKMMTAAYENLLSHESQTSDNNLPPRFVTLGGDHSIILPALRAL 175
D GDVPV + +C + N++S + P R + LGGDHSI P +RA+
Sbjct: 115 TDVGDVPVQEIRDC---GVDDDRLMNVISESVKLVMEEEPLRPLVLGGDHSISYPVVRAV 171
Query: 176 -RKTYGRLAVIHFDSHLDTWAPSKYPSFWHSDTSEFTHGSMLWIAHNEGLLTENNNIHAG 234
K G + ++H D+H P Y F + ++++H S G + G
Sbjct: 172 SEKLGGPVDILHLDAH-----PDIYDCF---EGNKYSHASSFARIMEGGYA--RRLLQVG 221
Query: 235 LRT-----RLSGSSF--EDYD----DDDKVGFHRIEADEIMDGGXXXXXXXXXXXXXXDV 283
+R+ R G F E Y+ D+ ++ E + G
Sbjct: 222 IRSINQEGREQGKRFGVEQYEMRTFSKDRPMLENLKLGEGVKG----------------- 264
Query: 284 PVYISVDIDVLDPSAAPGTGTMEVGGWMTRELIRIIRELEDLNLVGADIVEVSPPFDPTE 343
VYIS+D+D LDP+ APG +E GG R+++ I+ L+ ++VGAD+VE +P D +
Sbjct: 265 -VYISIDVDCLDPAFAPGVSHIEPGGLSFRDVLNILHNLQ-ADVVGADVVEFNPQRDTVD 322
Query: 344 -ITSLAGAQIAYELITNMVK 362
+T++ A++ EL + K
Sbjct: 323 GMTAMVAAKLVRELAAKISK 342
>At4g08870 [E] KOG2964 Arginase family protein
Length = 344
Score = 84.7 bits (208), Expect = 2e-16
Identities = 80/314 (25%), Positives = 134/314 (42%), Gaps = 44/314 (14%)
Query: 60 KFDIGVIGVPFDTAVSFRGGARFGPQAIRKA----SQRQTSMRGFNFRADINPYQDWASV 115
K ++GVP SF G P +R+A S T+ G + D +
Sbjct: 64 KATTALLGVPLGHNSSFLEGPALAPPHVREAIWCGSTNSTTEEGKELK-------DPRVL 116
Query: 116 VDCGDVPVTPM-----DNCLALKMMTAAYENLLSHESQTSDNNLPPRFVTLGGDHSIILP 170
D GD+PV + D+ +K+++ + + ++ E P R + +GGDHSI P
Sbjct: 117 SDVGDIPVQEIREMGVDDDRLMKVVSESVKLVMEEE--------PLRPLVIGGDHSISYP 168
Query: 171 ALRAL-RKTYGRLAVIHFDSHLDTWAPSKYPSFWHSDTSEFTHGSMLWIAHNEGLLTENN 229
+RA+ K G + ++H D+H D + ++ ++S S F + E
Sbjct: 169 VVRAVSEKLGGPVDILHLDAHPDIY--DRFEGNYYSHASSFAR------------IMEGG 214
Query: 230 NIHAGLRTRLSGSSFEDYDDDDKVGFHRIEADEIMDGGXXXXXXXXXXXXXXDVPVYISV 289
L+ + + E + + G +E E+ VYIS+
Sbjct: 215 YARRLLQVGIRSINKEGREQGKRFG---VEQYEMRTFSKDRQMLENLKLGEGVKGVYISI 271
Query: 290 DIDVLDPSAAPGTGTMEVGGWMTRELIRIIRELEDLNLVGADIVEVSPPFDPT-EITSLA 348
D+D LDP A G E GG R+++ I+ L+ +LVGAD+VE +P D ++T++
Sbjct: 272 DVDCLDPGFAHGVSHFEPGGLSFRDVLNILHNLQG-DLVGADVVEYNPQRDTADDMTAMV 330
Query: 349 GAQIAYELITNMVK 362
A+ EL M K
Sbjct: 331 AAKFVRELAAKMSK 344
>Hs10947139 [E] KOG2965 Arginase
Length = 322
Score = 72.8 bits (177), Expect = 9e-13
Identities = 80/331 (24%), Positives = 126/331 (37%), Gaps = 66/331 (19%)
Query: 59 KKFDIGVIGVPFDTAVSFRGGARFGPQAIRKASQRQTSMRGFNFRADINPYQDWASVVDC 118
K IG+IG PF RGG GP +RKA + + V D
Sbjct: 4 KSRTIGIIGAPFSKGQP-RGGVEEGPTVLRKAGLLEKLK------------EQECDVKDY 50
Query: 119 GDVPVTPMDNCLALKMMT------AAYENLLSHESQTSDNNLPPRFVTLGGDHSIILPAL 172
GD+P + N +++ A E L ++ N + LGGDHS+ + ++
Sbjct: 51 GDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRIS--LVLGGDHSLAIGSI 108
Query: 173 RALRKTYGRLAVIHFDSHLDTWAPSKYPSFWHSDTSEFTHGSMLWIAHNE---------- 222
+ + L VI D+H D P + TS HG + E
Sbjct: 109 SGHARVHPDLGVIWVDAHTDINTPL-------TTTSGNLHGQPVSFLLKELKGKIPDVPG 161
Query: 223 -----GLLTENNNIHAGLRT---------RLSGSSFEDYDDDDKVGFHRIEADEIMDGGX 268
++ + ++ GLR + G + + D++G ++ + +
Sbjct: 162 FSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETL----- 216
Query: 269 XXXXXXXXXXXXXDVPVYISVDIDVLDPSAAPGTGTMEVGGWMTRELIRIIRELEDLNLV 328
P+++S D+D LDPS P TGT VGG RE + I E+ L+
Sbjct: 217 ------SYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLL 270
Query: 329 -GADIVEVSPPF--DPTEITSLAGAQIAYEL 356
G DI+EV+P P E+T +A L
Sbjct: 271 SGLDIMEVNPSLGKTPEEVTRTVNTAVAITL 301
>Hs4502215 [E] KOG2965 Arginase
Length = 354
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/324 (25%), Positives = 129/324 (39%), Gaps = 55/324 (16%)
Query: 63 IGVIGVPFDTAVSFRGGARFGPQAIRKAS-QRQTSMRGFNFRADINPYQDWASVVDCGDV 121
+ VIG PF R G GP AIR+A ++ S G + + D GD+
Sbjct: 26 VAVIGAPFSQGQK-RKGVEHGPAAIREAGLMKRLSSLGCHLK-------------DFGDL 71
Query: 122 PVTPMD-----NCLALKMMTAAYENLLSHESQTSDNNLPPRFVTLGGDHSIILPALRALR 176
TP+ N L + + N E + + VTLGGDHS+ + +
Sbjct: 72 SFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHA 131
Query: 177 KTYGRLAVIHFDSHLDTWAPSKYPSF-WHSDTSEFTHGSML----------WIAHNEGLL 225
+ L V+ D+H D P S H F + WI + +
Sbjct: 132 RHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWI---KPCI 188
Query: 226 TENNNIHAGLRTRLSGSSF--EDYD-------DDDKVGFHRIEADEIMDGGXXXXXXXXX 276
+ + ++ GLR F ++YD D D++G ++
Sbjct: 189 SSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKV-----------MERTFDL 237
Query: 277 XXXXXDVPVYISVDIDVLDPSAAPGTGTMEVGGWMTRELIRIIRELEDLNLVGA-DIVEV 335
P+++S DID DP+ AP TGT VGG RE + I E+ + L+ A D+VEV
Sbjct: 238 LIGKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEV 297
Query: 336 SPPFDPTEITSLAGAQIAYELITN 359
+P +E + A +A ++I +
Sbjct: 298 NPQLATSEEEAKTTANLAVDVIAS 321
>CE07525_1 [E] KOG2965 Arginase
Length = 306
Score = 54.3 bits (129), Expect = 3e-07
Identities = 56/218 (25%), Positives = 87/218 (39%), Gaps = 24/218 (11%)
Query: 143 LSHESQTSDNNLPPRFVTLGGDHSIIL---PALRALRKTYGRLAVIHFDSHLDTWAPSKY 199
L+HE++ N + GGDHS + + + G + +I D+H+D P
Sbjct: 78 LAHETRQVIEN-KEELLVFGGDHSCAIGTWSGVATAMRPVGDIGLIWVDAHMDAHTPDT- 135
Query: 200 PSFWHSDTSEFTHGSMLWIAHNEG-----LLTENNNIHAGLRTRLSGSSFEDYDDDD--- 251
SDT HG + +AH G L+ + + L L DY+ +
Sbjct: 136 -----SDTGNI-HG--MPVAHLLGFGDKTLVKIGDRLPKLLPHNLCMVGIRDYESAEQEL 187
Query: 252 --KVGFHRIEADEIMDGGXXXXXXXXXXXXXXDVPVY-ISVDIDVLDPSAAPGTGTMEVG 308
K+G A E+ G + Y +S+D+D D S AP GT
Sbjct: 188 LEKLGVRIFYAHEVEKRGIQDVMQEAQYLVTRNTIGYGLSIDLDGFDVSYAPAVGTPSAD 247
Query: 309 GWMTRELIRIIRELEDLNLVGADIVEVSPPFDPTEITS 346
G E I+ + ++ L+ +IVE P FD T+ TS
Sbjct: 248 GINALEFIKALLTIDLTKLIATEIVEFLPRFDDTQRTS 285
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,335,591
Number of Sequences: 60738
Number of extensions: 1096101
Number of successful extensions: 2218
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2188
Number of HSP's gapped (non-prelim): 13
length of query: 410
length of database: 30,389,216
effective HSP length: 109
effective length of query: 301
effective length of database: 23,768,774
effective search space: 7154400974
effective search space used: 7154400974
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)