BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0025 (cbib) DE:cobalamin biosynthesis protein B (290 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||C75190 cobalamin biosynthesis protein B PAB0025 - Pyrococcu... 580 e-165 sp|O58114|COBD_PYRHO PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COB... 391 e-108 gi|11498934 cobalamin biosynthesis protein (cbiB) [Archaeoglobus... 232 3e-60 sp|Q58710|COBD_METJA PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COB... 202 4e-51 sp|O27460|COBD_METTH PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COB... 184 9e-46 gb|AAK43329.1| Cobalamin biosynthesis protein B (cbiB) [Sulfolob... 169 4e-41 emb|CAC11224.1| (AL445063) COBYRIC ACID SYNTHASE related protein... 167 2e-40 sp|Q52683|COBD_RHOCA COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|744... 152 4e-36 pir||S52223 hypothetical protein 945 - Rhodobacter capsulatus >g... 151 8e-36 emb|CAB40735.1| (AJ011317) CobD protein [Methylobacterium sp. CM4] 139 4e-32 dbj|BAB05307.1| (AP001512) cobalamin biosynthesis [Bacillus halo... 137 1e-31 sp|P21634|COBD_PSEDE COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|949... 137 2e-31 pir||A83486 cobalamin biosynthetic protein CobD PA1275 [imported... 135 7e-31 gi|10957439 cobalamin biosynthesis protein CobD, putative [Deino... 127 1e-28 sp|Q05600|CBIB_SALTY CBIB PROTEIN >gi|154421|gb|AAA27253.1| (L12... 126 3e-28 gb|AAG19854.1| (AE005070) Vng1578h [Halobacterium sp. NRC-1] 116 4e-25 sp|P74475|COBD_SYNY3 COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|744... 106 3e-22 sp|Q10518|COBD_MYCTU COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|744... 99 4e-20 emb|CAB59463.1| (AL132644) cobalamin biosynthesis protein [Strep... 93 4e-18 sp|Q9YAA0|COBD_AERPE PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COB... 93 4e-18 gb|AAG23557.1|AF244608_1 (AF244608) cobalamin biosynthesis prote... 73 3e-12 >pir||C75190 cobalamin biosynthesis protein B PAB0025 - Pyrococcus abyssi (strain Orsay) >gi|5457479|emb|CAB48970.1| (AJ248283) cobalamin biosynthesis protein B [Pyrococcus abyssi] Length = 290 Score = 580 bits (1478), Expect = e-165 Identities = 290/290 (100%), Positives = 290/290 (100%) Query: 1 MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV 60 MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV Sbjct: 1 MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV 60 Query: 61 ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSR 120 ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSR Sbjct: 61 ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSR 120 Query: 121 DVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDER 180 DVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDER Sbjct: 121 DVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDER 180 Query: 181 YEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKINSDKPIAAMSAVLGV 240 YEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKINSDKPIAAMSAVLGV Sbjct: 181 YEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKINSDKPIAAMSAVLGV 240 Query: 241 WLEKPGAYRFPGREPRDEDIKRALDVYKLVVAEYLSIVFVLKVVQLCLNP 290 WLEKPGAYRFPGREPRDEDIKRALDVYKLVVAEYLSIVFVLKVVQLCLNP Sbjct: 241 WLEKPGAYRFPGREPRDEDIKRALDVYKLVVAEYLSIVFVLKVVQLCLNP 290 >sp|O58114|COBD_PYRHO PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447318|pir||E71145 probable cobalamin biosynthesis protein D - Pyrococcus horikoshii >gi|3256767|dbj|BAA29450.1| (AP000002) 283aa long hypothetical cobalamin biosynthesis protein D [Pyrococcus horikoshii] Length = 283 Score = 391 bits (994), Expect = e-108 Identities = 189/274 (68%), Positives = 229/274 (82%), Gaps = 2/274 (0%) Query: 9 LALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGK-IGFLAGAFVTFIIVALAFFLS 67 LAL WDLLLGEPPA +HPVVWFGK+ F+D+ + RR I FLAG F T ++++ AF LS Sbjct: 6 LALGWDLLLGEPPAVVHPVVWFGKLIAFIDSHYSRRSPAIDFLAGLFATLVVLSFAFLLS 65 Query: 68 LIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSRDVKVLDL 127 ++P Y +PL+YLL++YLLKSSFAIRSLYEHV RT+ +D+EE RK VSMIVSRD L Sbjct: 66 ILPLYAPYPLNYLLSVYLLKSSFAIRSLYEHVRRTMKDDVEEMRKEVSMIVSRDTSKLGR 125 Query: 128 AHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDERYEYFGKF 187 HL SA+IESLAEN NDSVVAPLFY++LFGLPGA+VYRAVNTLDAM GYR RYEYFGKF Sbjct: 126 EHLISASIESLAENTNDSVVAPLFYYLLFGLPGALVYRAVNTLDAMVGYRTSRYEYFGKF 185 Query: 188 PARLDDILNFIPARLTVLLYLPFGV-KVLKYYKLARFKINSDKPIAAMSAVLGVWLEKPG 246 ARLDDILNF+PAR+TVLL+LP +V++YYK+ARFK+NSDKPIAAMSAVLG+WLEKP Sbjct: 186 SARLDDILNFLPARITVLLFLPLNPRRVIRYYKMARFKVNSDKPIAAMSAVLGIWLEKPN 245 Query: 247 AYRFPGREPRDEDIKRALDVYKLVVAEYLSIVFV 280 YRFPGR+PR EDI+RAL VY +VV+E++ ++ + Sbjct: 246 IYRFPGRDPRMEDIERALKVYVIVVSEWILLLLL 279 >gi|11498934 cobalamin biosynthesis protein (cbiB) [Archaeoglobus fulgidus] >gi|6225179|sp|O28933|COBD_ARCFU PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447320|pir||G69416 cobalamin biosynthesis protein (cbiB) homolog - Archaeoglobus fulgidus >gi|2649237|gb|AAB89908.1| (AE001011) cobalamin biosynthesis protein (cbiB) [Archaeoglobus fulgidus] Length = 290 Score = 232 bits (586), Expect = 3e-60 Identities = 131/286 (45%), Positives = 177/286 (61%), Gaps = 8/286 (2%) Query: 4 LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIVALA 63 +++L L+ D +GEPPA +HPVVW+GK+ L+ R+ + GAF I++ A Sbjct: 5 VVVLLTTLMLDAAVGEPPALLHPVVWYGKLISLLERAKFRKMLVEIFYGAFCCLIVITFA 64 Query: 64 FFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSRDVK 123 LSL+P +PL++L A+YLL SS +++S+ H V ++ RK V MIVSR+ + Sbjct: 65 LILSLLP--FPYPLNFLWAVYLLFSSISVKSMVNHARVCVESGVD--RKAVQMIVSRNTE 120 Query: 124 VLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDERYEY 183 L L SA IES+AEN D VVAPLFYF +FG+ GA+VYRAVNT DAM GYR RYE Sbjct: 121 ELSEEQLCSAVIESVAENYVDGVVAPLFYFSIFGVAGAVVYRAVNTCDAMVGYRKGRYEA 180 Query: 184 FGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKINSDKPIAAMSAVLGVWLE 243 FGKF ARLDDILN+IPARL++L + Y K+N IAAMS +LGV LE Sbjct: 181 FGKFAARLDDILNYIPARLSLLFFELLKRGAFSYGLKRNVKLNG-CAIAAMSYLLGVKLE 239 Query: 244 KPGAYRFPGREPRDEDIKRALDVY---KLVVAEYLSIVFVLKVVQL 286 KPG Y PG EP DI+RA+ + ++ + +I +++V L Sbjct: 240 KPGYYSLPGIEPSAADIERAIKAFVRLTVIAVIFTTIAVSIRIVLL 285 >sp|Q58710|COBD_METJA PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|2127814|pir||A64464 cobalamin biosynthesis protein D homolog - Methanococcus jannaschii >gi|1591953|gb|AAB99321.1| (U67571) cobalamin biosynthesis protein B (cbiB) [Methanococcus jannaschii] Length = 307 Score = 202 bits (509), Expect = 4e-51 Identities = 122/303 (40%), Positives = 181/303 (59%), Gaps = 28/303 (9%) Query: 1 MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWR----RRGKIGFLAGAFVT 56 +NP+IL LA+I+D ++GE P IHP VW GK+ FL+N ++ + FL G+ T Sbjct: 2 LNPIILF-LAIIFDRIIGELPESIHPTVWIGKLIAFLENIFKSTNCKNKYRDFLFGSLTT 60 Query: 57 FIIV----ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTV----TEDIE 108 FI + +AFF+ L FPL+Y++ +LL ++ +SL+E + + D+E Sbjct: 61 FITLLVVGVIAFFVDKCIMLLPFPLNYIIYGFLLSTTIGYKSLFEFCKKPIEYIKNGDLE 120 Query: 109 EKRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVN 168 RK V IVSRD LD H+ SAA+ESL+EN+ DS++ LFY + FGLPGA VYRA+N Sbjct: 121 GARKAVQHIVSRDASKLDKEHVLSAAVESLSENITDSIIGALFYAIFFGLPGAFVYRAIN 180 Query: 169 TLDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYL---PF---GVKVLKYYKLAR 222 TLDAM GY++E+Y ++GK ARLDDI NFIP+R+ +L + PF VK Y L Sbjct: 181 TLDAMIGYKNEKYLWYGKLAARLDDIANFIPSRIAGILLIITAPFYKGDVKKAIYGFLKE 240 Query: 223 F----KINSDKPIAAMSAVLGVWLEKPGAYRFPGREPRDEDIKRALDVYKLVVAEYLSIV 278 NS +A ++ L + LEK G Y+ + D++++L+ +K V +Y +V Sbjct: 241 ANKVPSPNSGYTMATLANALNITLEKIGYYKLGSGK---IDVEKSLNAFKAV--DYTVVV 295 Query: 279 FVL 281 F++ Sbjct: 296 FLI 298 >sp|O27460|COBD_METTH PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447313|pir||F69054 cobalamin biosynthesis protein B - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622521|gb|AAB85886.1| (AE000903) cobalamin biosynthesis protein B [Methanobacterium thermoautotrophicum] Length = 297 Score = 184 bits (463), Expect = 9e-46 Identities = 119/285 (41%), Positives = 163/285 (56%), Gaps = 24/285 (8%) Query: 1 MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV 60 M+ + +L LA+I DLL+GEPP ++HPVVW G W R + I V Sbjct: 1 MSEVSVLLLAVILDLLIGEPPHRLHPVVWMGSAV-----EWMRNILGNSRISGIILTIAV 55 Query: 61 ALAFFLSL-IPSYLTFPLDYLLAIYLLKSSFAIRSLYE---HVARTVTEDIEEKRKTVSM 116 A F L L + ++L PL+ +++ LL + +IR L V ++ EDIE+ R+ +SM Sbjct: 56 AAPFTLPLFLINHLQDPLNLIISSILLSAVISIRMLVTSALEVGGSLKEDIEDARRKLSM 115 Query: 117 IVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGY 176 +VSRD L + SAAIE+L EN+ DSV AP+FYF+L GLPGA +YR VNTLDAM GY Sbjct: 116 LVSRDTTSLSDEQITSAAIETLTENITDSVTAPIFYFILLGLPGAFLYRVVNTLDAMVGY 175 Query: 177 RDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKI----------- 225 D G FPARLDDILN+IP+R+T +L +P + + ++ F+I Sbjct: 176 LDSENRDIGWFPARLDDILNYIPSRITGVLMVPAALLLGMNWR-GSFRILLRDARRTPSP 234 Query: 226 NSDKPIAAMSAVLGVWLEKPGAYRFPGREPRDE-DIKRALDVYKL 269 NS +AA + L V LEKPG Y +P D D ++ LD KL Sbjct: 235 NSGFTMAAAAGALSVQLEKPGVYVL--GDPCDGLDNEKLLDAVKL 277 >gb|AAK43329.1| Cobalamin biosynthesis protein B (cbiB) [Sulfolobus solfataricus] Length = 305 Score = 169 bits (423), Expect = 4e-41 Identities = 105/288 (36%), Positives = 162/288 (55%), Gaps = 20/288 (6%) Query: 4 LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRR--GKIGFLAGAFVTFIIVA 61 L +L LALIWDL + EPP IHPVVW GKI+ L ++ G I ++ +I Sbjct: 2 LFILALALIWDLTISEPPIYIHPVVWTGKISEILIKPYKGYFYGVILWILSVLPPLLIFV 61 Query: 62 LAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSRD 121 ++ IP YL ++ + LK++F+I+ LY+ V + D ++ R IV RD Sbjct: 62 YLPIVAEIPIYLKI----IILTFSLKTTFSIKMLYDIVTKGSRLD-DQARYYAQQIVRRD 116 Query: 122 VKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDERY 181 + + H+ SA IESL E+ D + +P+F+F++FGL GAM+ R NT+D+M GY+ Sbjct: 117 LSKSEKGHIASALIESLFESTVDGITSPIFWFLIFGLIGAMLQRLANTMDSMVGYKTPEL 176 Query: 182 EYFGKFPARLDDILNFIPARLTVLLYLPFGV----------KVLKYYKLARFKINSDKPI 231 G F A++D ILN+IPARLT ++ L G+ K L+ K+ +N+ PI Sbjct: 177 RKEGWFSAKIDTILNYIPARLTGMIMLIAGLILGLDVKQGWKALREAKME--SVNAKYPI 234 Query: 232 AAMSAVLGVWLEKPGAYRFP-GREPRDEDIKRALDVYKLVVAEYLSIV 278 A + +L V LEK G Y+ G P ++DI++AL ++KL + Y ++ Sbjct: 235 AIAAGLLNVSLEKVGHYKVGFGNLPCEDDIEKALKLFKLSLILYFLVI 282 >emb|CAC11224.1| (AL445063) COBYRIC ACID SYNTHASE related protein [Thermoplasma acidophilum] Length = 304 Score = 167 bits (418), Expect = 2e-40 Identities = 104/299 (34%), Positives = 175/299 (57%), Gaps = 22/299 (7%) Query: 4 LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV--A 61 +IL+G A+ D++ GEP IHPVV+ GK++ ++ +R F +IV A Sbjct: 3 IILIG-AIAIDIIFGEPKEYIHPVVFSGKVSKRIETYFRHHDNRIVYGSIFAVAVIVITA 61 Query: 62 LAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTE-----DIEEKRKTVSM 116 + +FL++ S + ++++ +LK++F+I ++ +H+ R V E +I + R +S Sbjct: 62 IPYFLAIYVSSFVLVIYVIVSMVILKTTFSISAMGDHI-RLVVESLKNGNISDARVYLSR 120 Query: 117 IVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGY 176 +V RD L+ ++SAAIE++AE L D + PLF+F+ G+PGA V R +NTLD+M GY Sbjct: 121 VVRRDTSNLNENEISSAAIETIAEGLVDGYMTPLFFFIFLGIPGAFVARIINTLDSMCGY 180 Query: 177 RDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYK--------LARF-KINS 227 +D FG+F A +D ++N+IPARL+ ++ F VL Y ++RF +N+ Sbjct: 181 KDRENFEFGRFSAFMDTVINYIPARLS-WFFIGFSADVLNYRHKVISPRKYVSRFDSVNA 239 Query: 228 DKPIAAMSAVLGVWLEKPGAY--RFPGREPRDEDIKRALDVYKLVVAEYLSIVFVLKVV 284 PI+ M+ L + LEK G+Y G +P DI+R++ V+ + V Y +I+FVL ++ Sbjct: 240 GWPISTMACALNLRLEKRGSYIVNDEGYQPSVRDIERSMHVFYVAVYSY-TIIFVLPLL 297 >sp|Q52683|COBD_RHOCA COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447319|pir||T03524 cobD protein - Rhodobacter capsulatus >gi|3128325|gb|AAC16177.1| (AF010496) CobD protein [Rhodobacter capsulatus] Length = 314 Score = 152 bits (381), Expect = 4e-36 Identities = 105/311 (33%), Positives = 157/311 (49%), Gaps = 28/311 (9%) Query: 1 MNPLILLGLALIWDLLLGEPPAKI----HPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVT 56 MN ++ +A+ DL LG P A HPV W G + L+ W +G++ L G V Sbjct: 1 MNFAAMMVVAIGIDLALGWPDALYKRIGHPVTWIGALIARLEKGWNFKGRLRRLRGVLVA 60 Query: 57 FIIVALAFFLSLIPSYLTFPLDY---LLAIYLLKSSFAIRSLYEHVART----VTEDIEE 109 ++ ++L L P + L+ L A+RS+++HVA + D+ Sbjct: 61 LAVIGTTVVIALAVQ-LWLPAGWPGVLIGGILAWPFVALRSMHDHVAAVAKPLIAGDLPG 119 Query: 110 KRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNT 169 R+ VSMIV RD LD + AA+ESLAEN +D +VAPLF+ + GLPG Y+A+NT Sbjct: 120 ARQAVSMIVGRDPSQLDQPGVARAALESLAENSSDGIVAPLFWGCVAGLPGIAGYKAINT 179 Query: 170 LDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYL------PFGVKVLKYYKLARF 223 LD+M G+R +RYE FG AR+DD++N IPARLT L + + V+ + Sbjct: 180 LDSMIGHRTDRYEEFGWASARIDDLVNLIPARLTGLFFALASPCRARALAVMARDARSHR 239 Query: 224 KINSDKPIAAMSAVLGVWLEKPGAY----------RFPGREPRDEDIKRALDVYKLVVAE 273 N+ P AAM+ L V L P Y +PR D+ R L +Y+ +A Sbjct: 240 SPNAGWPEAAMAGALAVRLSGPRIYADRVANEPWLNGTAPDPRPADLARGLALYRRAMAG 299 Query: 274 YLSIVFVLKVV 284 ++ ++ V+ Sbjct: 300 MTLVIGLVAVL 310 >pir||S52223 hypothetical protein 945 - Rhodobacter capsulatus >gi|609232|emb|CAA86581.1| (Z46611) (=ORF945) [Rhodobacter capsulatus] Length = 314 Score = 151 bits (378), Expect = 8e-36 Identities = 104/311 (33%), Positives = 157/311 (50%), Gaps = 28/311 (9%) Query: 1 MNPLILLGLALIWDLLLGEPPAKI----HPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVT 56 MN ++ +A+ DL LG P A HPV W ++ L+ W +G++ L G V Sbjct: 1 MNFAAMMVVAIGIDLALGWPDALYKRIGHPVTWIARLIARLEKGWNFKGRLRRLRGVLVA 60 Query: 57 FIIVALAFFLSLIPSYLTFPLDY---LLAIYLLKSSFAIRSLYEHVART----VTEDIEE 109 ++ ++L L P + L+ L A+RS+++HVA + D+ Sbjct: 61 LAVIGTTVVIALAVQ-LWLPAGWPGVLIGGILAWPFVALRSMHDHVAAVAKPLIAGDLPG 119 Query: 110 KRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNT 169 R+ VSMIV RD LD + AA+ESLAEN +D +VAPLF+ + GLPG Y+A+NT Sbjct: 120 ARQAVSMIVGRDPSQLDQPGVARAALESLAENSSDGIVAPLFWGCVAGLPGIAGYKAINT 179 Query: 170 LDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYL------PFGVKVLKYYKLARF 223 LD+M G+R +RYE FG AR+DD++N IPARLT L + + V+ + Sbjct: 180 LDSMIGHRTDRYEEFGWASARIDDLVNLIPARLTGLFFALASPCRARALAVMARDARSHR 239 Query: 224 KINSDKPIAAMSAVLGVWLEKPGAY----------RFPGREPRDEDIKRALDVYKLVVAE 273 N+ P AAM+ L V L P Y +PR D+ R L +Y+ +A Sbjct: 240 SPNAGWPEAAMAGALAVRLSGPRIYADRVANEPWLNGTAPDPRPADLARGLALYRRAMAG 299 Query: 274 YLSIVFVLKVV 284 ++ ++ V+ Sbjct: 300 MTLVIGLVAVL 310 >emb|CAB40735.1| (AJ011317) CobD protein [Methylobacterium sp. CM4] Length = 330 Score = 139 bits (347), Expect = 4e-32 Identities = 112/313 (35%), Positives = 152/313 (47%), Gaps = 36/313 (11%) Query: 4 LILLGLALIWDLLLGEPPAKI----HPVVWFGKIAGFLDNRWRRRGKIGF--LAGAFVTF 57 LI+L LAL+ + G P A HPV W G++ LD R RG+ G L G Sbjct: 13 LIILALALLIEAAAGYPDALYRALGHPVTWIGRLIAALD-RGLNRGEPGARRLKGVLALL 71 Query: 58 IIVALA----FFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVT----EDIEE 109 +++A A L+ + L +LA L + A RSL +HV R E + Sbjct: 72 VLLAAATGAGLALTALAGLAGPVLGLVLAALLCATLPAQRSLDQHVIRVAAALRREGLPA 131 Query: 110 KRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNT 169 R+ VSMIV RD + LD A + AAIESLAEN +D +VAP F+ L GLPG ++Y+A NT Sbjct: 132 GRRAVSMIVGRDPETLDEAAVCRAAIESLAENFSDGIVAPAFWIGLGGLPGGLLYKAANT 191 Query: 170 LDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLY-----LPFGVKVLKYYKLARFK 224 D+M G+R R+ FG AR DD++N +RLT LL L G + R Sbjct: 192 ADSMIGHRTPRHGAFGWAAARFDDLINLPASRLTALLIMAAARLTKGASARGAWAAVRRD 251 Query: 225 I------NSDKPIAAMSAVLGVWLEKPGAY---------RFPGR-EPRDEDIKRALDVYK 268 N+ P AAM+ LG+ L P Y GR E EDI+RA+ +Y+ Sbjct: 252 AGRHRSPNAGWPEAAMAGALGLRLAGPRVYGGERVTDSWMGDGRAEAGPEDIERAIRIYR 311 Query: 269 LVVAEYLSIVFVL 281 A + +L Sbjct: 312 TACALLFGLAAIL 324 >dbj|BAB05307.1| (AP001512) cobalamin biosynthesis [Bacillus halodurans] Length = 319 Score = 137 bits (342), Expect = 1e-31 Identities = 102/306 (33%), Positives = 155/306 (50%), Gaps = 28/306 (9%) Query: 4 LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRW---RRRGKIGFLAGAFVTFIIV 60 +I + A I D LG+P HPVV GK+ + + RW R R + G L V I+ Sbjct: 6 VIAIVSAFILDKWLGDPKWLPHPVVGMGKLITYFERRWNCGRWRREKGVLLLLTVLLIVT 65 Query: 61 ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYE---HVARTV-TEDIEEKRKTVSM 116 AL+ L + + L ++ L+ S+ A + L E VAR + T ++ E R+ +S Sbjct: 66 ALSLALVWLSYQVHLLLGVIVEALLIASTIAAKGLKEAAEEVARPLATRNLLEARRKLSY 125 Query: 117 IVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGY 176 IV RD LD + AIE++AEN +D V APLFY ++ G P A++YRA NT D+M GY Sbjct: 126 IVGRDTDQLDEKEIARGAIETVAENTSDGVTAPLFYALIGGAPLALLYRATNTCDSMVGY 185 Query: 177 RDERYEYFGKFPARLDDILNFIPARLTVLLYL---------PFG--VKVLKYYKLARFKI 225 ++ERY FG A+ DD+LN++P+R+T +L L P G +K+L Sbjct: 186 KNERYRDFGWASAKFDDVLNWVPSRITGVLMLLLHRKRRQAPLGQSLKMLAREAKKHPSP 245 Query: 226 NSDKPIAAMSAVLGVWLEKPGAYR----------FPGREPRDEDIKRALDVYKLVVAEYL 275 NS AAM+ +L V L Y+ + + +DI ++ + V +L Sbjct: 246 NSGWGEAAMALLLHVTLGGTNTYQGMTSERAKMGYGTKAMTAKDIDESIAIMNRTVLGFL 305 Query: 276 SIVFVL 281 +F+L Sbjct: 306 VFLFLL 311 >sp|P21634|COBD_PSEDE COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|94951|pir||E36144 cobD protein - Pseudomonas sp >gi|151149|gb|AAA25776.1| (M59236) ORF 5 [Pseudomonas denitrificans] Length = 323 Score = 137 bits (341), Expect = 2e-31 Identities = 99/272 (36%), Positives = 141/272 (51%), Gaps = 28/272 (10%) Query: 4 LILLGLALIWDLLLGEPP---AKI-HPVVWFGKIAGFLDNRWRRR----GKIGFLAGAFV 55 L++L LAL+ D ++G+P A++ HPVV+FGK GF D R R F + Sbjct: 6 LLILALALVIDRVVGDPDWLWARVPHPVVFFGKAIGFFDARLNREDLEDSARKFRGVVAI 65 Query: 56 TFIIVALAFFLSLIPSYLTF--PLDYLLAIYLLKSSFAIRSLYEHVARTV----TEDIEE 109 ++ A+F L+ PL +LL L+ A +SL +HV R +E Sbjct: 66 LLLLGISAWFGHLLHRLFAVLGPLGFLLEAVLVAVFLAQKSLADHVRRVAGGLRQGGLEG 125 Query: 110 KRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNT 169 R VSMIV RD K LD + AAIESLAEN +D VVAP F++ + GLPG + Y+ +NT Sbjct: 126 GRAAVSMIVGRDPKTLDEPAVCRAAIESLAENFSDGVVAPAFWYAVAGLPGLLAYKMLNT 185 Query: 170 LDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKI---- 225 D+M G++ +Y +FG ARLDD+ N ARL++LL + G + + A+ + Sbjct: 186 ADSMIGHKSPKYLHFGWASARLDDLANLPAARLSILL-ISAGALIHRGASAAKDALTVAL 244 Query: 226 ---------NSDKPIAAMSAVLGVWLEKPGAY 248 NS P AAM+ L + L P Y Sbjct: 245 RDHGLHRSPNSGWPEAAMAGALDLQLAGPRIY 276 >pir||A83486 cobalamin biosynthetic protein CobD PA1275 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9947209|gb|AAG04664.1|AE004557_5 (AE004557) cobalamin biosynthetic protein CobD [Pseudomonas aeruginosa] Length = 312 Score = 135 bits (336), Expect = 7e-31 Identities = 102/304 (33%), Positives = 152/304 (49%), Gaps = 37/304 (12%) Query: 6 LLG-LALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIG------------FLAG 52 LLG L ++ D GEP HP+V FG++A L+ R+ R G A Sbjct: 4 LLGILGVVLDARFGEPQGW-HPLVAFGRLADRLERRFNRSRLAGEADPGVGWRSHGVTAW 62 Query: 53 AFVTFIIVALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTE----DIE 108 + LA+ L+ +P L +L+ L ++ +RSL EH D++ Sbjct: 63 VLAVLPLTLLAWALAELPY-----LGWLVQALALYAALGLRSLGEHAEPVALALRAGDLD 117 Query: 109 EKRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVN 168 E R+ V +VSRD + LD A + AA ES+ EN +D+V A LF+F + G PG ++YR N Sbjct: 118 EARRRVGYLVSRDTRELDQAGVARAATESVLENGSDAVYAALFWFAVAGAPGVVLYRLSN 177 Query: 169 TLDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYLPFG-----VKVLKYYKLARF 223 TLDAM+GYR+ R+E FG A++DDILN++PARL L Y G ++ + Sbjct: 178 TLDAMWGYRNARFERFGWAAAKIDDILNYLPARLVALTYALLGDTRQALRCWREQAPQWD 237 Query: 224 KINSDKPIAAMSAVLGVWLEKPGAYR---------FPGREPRDEDIKRALDVYKLVVAEY 274 N+ +AA + LGV+L Y G +P+ DI RAL + + V + Sbjct: 238 SPNAGPVMAAGAGALGVFLGGAAIYHGELHQRPLLGSGPQPQGRDIYRALALVRQGVLLW 297 Query: 275 LSIV 278 L ++ Sbjct: 298 LLVL 301 >gi|10957439 cobalamin biosynthesis protein CobD, putative [Deinococcus radiodurans] >gi|7473449|pir||B75619 probable cobalamin biosynthesis protein CobD - Deinococcus radiodurans (strain R1) >gi|6460868|gb|AAF12572.1|AE001826_41 (AE001826) cobalamin biosynthesis protein CobD, putative [Deinococcus radiodurans] Length = 300 Score = 127 bits (317), Expect = 1e-28 Identities = 102/272 (37%), Positives = 135/272 (49%), Gaps = 19/272 (6%) Query: 5 ILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRW-RRRGKIGFLAGAFVTFIIVALA 63 +LL LAL LGEPPA HPV++ G + W + K F GA AL Sbjct: 8 LLLALALD---TLGEPPAYFHPVIYMGNYLRWAQTHWCGKTAKQQFTQGAAGW----ALG 60 Query: 64 FFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTE----DIEEKRKTVSM-IV 118 L+ + L + + LLK A ++L++ VA D+ E R+ ++ +V Sbjct: 61 AGLAAGAGWTASGLPWWVQGALLKPLLARKALFDAVAEVAGALEQGDVPEARRLLAWHLV 120 Query: 119 SRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRD 178 SRD L A + AAIESLAENL+DSVVAPL + GLP A YR NT DAM+GYR Sbjct: 121 SRDTSQLTAAEVAGAAIESLAENLSDSVVAPLLAYRAGGLPLAAAYRLTNTADAMWGYRT 180 Query: 179 ERYEYFGKFPARLDDILNFIPARLTVLLYLPF-GVKVLKYYKLAR---FKINSDKPIAAM 234 E GK A+ DD+ N PARLT L L G + + + R N+ P++A Sbjct: 181 PELEDAGKAAAKADDLFNLAPARLTALCTLMVSGSQSWRVWVRDRRNPASPNAGHPMSAF 240 Query: 235 SAVLGVWLEKPGAY--RFPGREPRDEDIKRAL 264 + LGV L+K G Y G P E + AL Sbjct: 241 AGALGVRLDKRGVYVLNAAGAAPGPEHLAPAL 272 >sp|Q05600|CBIB_SALTY CBIB PROTEIN >gi|154421|gb|AAA27253.1| (L12006) putative [Salmonella typhimurium] Length = 319 Score = 126 bits (314), Expect = 3e-28 Identities = 86/262 (32%), Positives = 136/262 (51%), Gaps = 23/262 (8%) Query: 9 LALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRR--GKIGFLAGAFVTFIIVA----- 61 +A + D ++G+P HPV W G++ F+ RR G G V +++V Sbjct: 8 IAWVLDFIIGDPQHWPHPVRWIGRLITFVQRIVRRYCPGDKALRIGGGVMWVVVVGATWG 67 Query: 62 LAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTE-----DIEEKRKTVSM 116 +A+ + + + + + ++++ ++ A RSL H A+ V D+ E R +S Sbjct: 68 VAWGVLALAQRIHPWFGWSVEVWMIFTTLAGRSL-AHAAQEVERPLRKNDLAESRIKLSW 126 Query: 117 IVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGY 176 IV RD L A +N A +E++AEN D ++APLF+ L G P AM Y+AVNTLD+M GY Sbjct: 127 IVGRDTSQLQPAQINRAVVETVAENTVDGIIAPLFFLFLGGAPLAMAYKAVNTLDSMVGY 186 Query: 177 RDERYEYFGKFPARLDDILNFIPARLT-VLLYLPFGVKVLKYYKLARF----KINSDKPI 231 + E+Y G AR+DD+ N++PARL+ +LL + G+ L ++ R + N P Sbjct: 187 KHEKYRAIGMVSARMDDVANYLPARLSWLLLGIAAGLCRLSGWRALRIGWRDRYNHSSPN 246 Query: 232 AAMS-----AVLGVWLEKPGAY 248 A S LG+ L P Y Sbjct: 247 CAWSEACVAGALGIQLGGPNNY 268 >gb|AAG19854.1| (AE005070) Vng1578h [Halobacterium sp. NRC-1] Length = 308 Score = 116 bits (287), Expect = 4e-25 Identities = 88/262 (33%), Positives = 127/262 (47%), Gaps = 23/262 (8%) Query: 5 ILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIVALAF 64 + +G+AL D + EPPA HPV WFG+ G +D W R +G LA + A + Sbjct: 9 VAVGVAL--DAAIAEPPAGCHPVAWFGRAVGVVDRPWTRPLAVGALAAIALPLAAAATVW 66 Query: 65 FLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEH----VARTVTED-IEEKRKTVSMIVS 119 + ++ + ++A ++ + + R L +A T TE+ ++ R+ + + Sbjct: 67 AAVTVATWGSALAGAVVAGLVVFVTTSRRMLLAEASGVIAATRTENSLDAARRRLRALAG 126 Query: 120 RDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFML--------FGLPGAMVYRAVNTLD 171 RD L L SAA+ES AENL D +VAPL F + G A +AVNTLD Sbjct: 127 RDPDALSAGELRSAAVESTAENLADGLVAPLAAFAVGAAVVSLPVGAAAAAWVKAVNTLD 186 Query: 172 AMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLY-----LPFGVKVLKYYKLARFKIN 226 +M GYR +R G ARLDD + ++PARL +L P V A N Sbjct: 187 SMLGYRSKR---VGTASARLDDAVMWVPARLAAVLIAATARAPAAVSRAAADAGAPPSPN 243 Query: 227 SDKPIAAMSAVLGVWLEKPGAY 248 S P+A ++AVL L KPG Y Sbjct: 244 SGWPMATLAAVLDCRLVKPGVY 265 >sp|P74475|COBD_SYNY3 COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447314|pir||S76447 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1653664|dbj|BAA18576.1| (D90915) CbiB protein [Synechocystis sp.] Length = 342 Score = 106 bits (263), Expect = 3e-22 Identities = 86/271 (31%), Positives = 134/271 (48%), Gaps = 26/271 (9%) Query: 4 LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRR---GKIGFLAGAFVTFIIV 60 +I+LG + + D LLG+P + HPV + G + F R+ L G F+ I+ Sbjct: 14 VIILGGSALLDFLLGDPKSWRHPVEFIGSVINFASQLIIRKVNDKNSRRLWGIFLGLKII 73 Query: 61 ALAFFLSLIPSYLTFPLDYLLAIYL----LKSSFAIRSLYEHVARTVTE-----DIEEKR 111 + FL+ + YL + +LA+ + + S FA SL + A++V E D+ R Sbjct: 74 ISSGFLAWLIVYLAEKVSPVLAVIIQIIGVASCFAGHSLAQ-AAQSVIEPLKAGDLPTAR 132 Query: 112 KTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGL-------PGAMVY 164 + +++ V RD L + A +ES+AEN D V +PLFY +L L P A+ Y Sbjct: 133 QKLALFVGRDTNNLSEREILRATVESVAENTVDGVTSPLFYALLGILFPFVGPWPLAIAY 192 Query: 165 RAVNTLDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARF- 223 +A +TLD+M GY+ E Y G F ARL+D L ++P RLTV + K + + + R Sbjct: 193 KAASTLDSMVGYKREPYTDLGWFSARLEDYLTWLPCRLTVFMLAILSGKPKQTWAIVRRD 252 Query: 224 -----KINSDKPIAAMSAVLGVWLEKPGAYR 249 NS A +A+LG+ L Y+ Sbjct: 253 GPLDPSPNSGWSEAIYAAILGIQLGGDNYYQ 283 >sp|Q10518|COBD_MYCTU COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447317|pir||H70777 probable cobD - Mycobacterium tuberculosis (strain H37RV) >gi|1261938|emb|CAA94658.1| (Z70692) cobD [Mycobacterium tuberculosis] Length = 313 Score = 99.5 bits (244), Expect = 4e-20 Identities = 90/298 (30%), Positives = 134/298 (44%), Gaps = 42/298 (14%) Query: 5 ILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIVALAF 64 +L+G L D++ G+P + HPV FG+ A L+ R G++ AGA ++V Sbjct: 13 VLIGCLL--DVVFGDPK-RGHPVALFGRAAAKLEQITYRDGRV---AGAVHVGLLVGAVG 66 Query: 65 FLSL-----------IPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKT 113 L + + T L L ++ I L E +D+E R+ Sbjct: 67 LLGAALQRLPGRSWPVAATATATWAALGGTSLARTGRQISDLLER------DDVEAARRL 120 Query: 114 VSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAM 173 + + RD L L AA+ES+AEN D+ V PL + G+P + YRA+NTLD+M Sbjct: 121 LPSLCGRDPAQLGGPGLTRAALESVAENTADAQVVPLLWAASSGVPAVLGYRAINTLDSM 180 Query: 174 FGYRDERYEYFGKFPARLDDILNFIPARLTVLLYL---------PFG-VKVLKYYKLARF 223 GYR RY FG ARLDD N++ AR T +L + P G V+ + Sbjct: 181 IGYRSPRYLRFGWAAARLDDWANYVGARATAVLVVICAPVVGGSPRGAVRAWRRDAARHP 240 Query: 224 KINSDKPIAAMSAVLGVWLEKPGAYRF---------PGREPRDEDIKRALDVYKLVVA 272 N+ AA + L V L P Y GR P+ D++RA+ + ++V A Sbjct: 241 SPNAGVVEAAFAGALDVRLGGPTRYHHELQIRPTLGDGRSPKVADLRRAVVLSRVVQA 298 >emb|CAB59463.1| (AL132644) cobalamin biosynthesis protein [Streptomyces coelicolor A3(2)] Length = 327 Score = 92.8 bits (227), Expect = 4e-18 Identities = 74/206 (35%), Positives = 104/206 (49%), Gaps = 17/206 (8%) Query: 11 LIWDLLLGEPPAKIHPVVWFGKIAGFLDN-RWRRRGKIGFL------AGAFVTFIIVALA 63 L+ DLLLG+P + HPV FG+ AG ++ WR G L GA V A A Sbjct: 15 LLGDLLLGDP-RRGHPVAAFGRAAGAVERVLWRDHRGWGTLHTVVCAGGAAVLGSAAAHA 73 Query: 64 FFLSLIPSY-LTFPLDYLLA--IYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSR 120 S S LT + + L + + AI E D+E R + + R Sbjct: 74 VRRSSAASVALTAAATWSVVGGTSLAREATAIGRALE------AGDVEAARARLPHLCGR 127 Query: 121 DVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDER 180 D + LD + A +ES+AEN +D+VV L + + G+PG + +RAVNTLDAM G++ R Sbjct: 128 DPQALDADGIARAVVESVAENTSDAVVGALVWGAVAGVPGLLGFRAVNTLDAMVGHKSPR 187 Query: 181 YEYFGKFPARLDDILNFIPARLTVLL 206 Y +G ARLDD+ + ARLT +L Sbjct: 188 YRRYGWASARLDDLAGWPGARLTAVL 213 >sp|Q9YAA0|COBD_AERPE PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447316|pir||A72508 probable cobalamin biosynthesis protein APE2039 - Aeropyrum pernix (strain K1) >gi|5105737|dbj|BAA81049.1| (AP000063) 323aa long hypothetical cobalamin biosynthesis protein [Aeropyrum pernix] Length = 323 Score = 92.8 bits (227), Expect = 4e-18 Identities = 74/203 (36%), Positives = 101/203 (49%), Gaps = 15/203 (7%) Query: 68 LIPSYLTFPLDYLLAI-YLLKSSFAIRSLYEHVART----VTEDIEEKRKTVSMIVSRDV 122 L SYL P + LA+ ++K S +R L + + +E R+ V IV RD+ Sbjct: 85 LAASYLVHPALHTLAVGVIVKLSMPLRLLLDTCIKASRMAAAGRVECSRRLVQGIVRRDL 144 Query: 123 KVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDERYE 182 L + SA IES AE+L D +PL Y++L G GA++ R NTLD G++ Sbjct: 145 SGEPLGRVLSACIESTAESLVDGYTSPLTYYILLGPLGALLQRLSNTLDGAVGFKTPLLY 204 Query: 183 YFGKFPARLDDILNFIPARLT---VLLYLPF-GVKVLKYYK-LARF-----KINSDKPIA 232 G F A+ D +LNFIPARLT V L P G L + +AR +N+ PI+ Sbjct: 205 RQGWFSAKADTLLNFIPARLTAVMVALAAPLAGASTLGSLRCIARCARLLESVNAGYPIS 264 Query: 233 AMSAVLGVWLEKPGAYRFPGREP 255 A + L V LEK G Y G P Sbjct: 265 AFAGALDVRLEKKGFYIVNGGAP 287 >gb|AAG23557.1|AF244608_1 (AF244608) cobalamin biosynthesis protein CobD [Carboxydothermus hydrogenoformans] Length = 149 Score = 73.4 bits (177), Expect = 3e-12 Identities = 33/61 (54%), Positives = 45/61 (73%), Gaps = 1/61 (1%) Query: 157 GLPGAMVYRAVNTLDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLK 216 GLPG YR VNTLD+M GY+ ERY YFG+ A+LDD+LN++PAR+T +L + +L+ Sbjct: 3 GLPGVWFYRTVNTLDSMVGYKSERYLYFGRIAAKLDDLLNYLPARITGVL-MVLAAFILR 61 Query: 217 Y 217 Y Sbjct: 62 Y 62 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.328 0.146 0.437 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 103805003 Number of Sequences: 2977 Number of extensions: 4106562 Number of successful extensions: 14187 Number of sequences better than 1.0e-10: 21 Number of HSP's better than 0.0 without gapping: 19 Number of HSP's successfully gapped in prelim test: 2 Number of HSP's that attempted gapping in prelim test: 14127 Number of HSP's gapped (non-prelim): 23 length of query: 290 length of database: 189,106,746 effective HSP length: 51 effective length of query: 239 effective length of database: 158,583,909 effective search space: 37901554251 effective search space used: 37901554251 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 40 (21.7 bits) S2: 165 (68.7 bits)