BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0025 (cbib) DE:cobalamin biosynthesis protein B
         (290 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75190 cobalamin biosynthesis protein B PAB0025 - Pyrococcu...   580  e-165
sp|O58114|COBD_PYRHO PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COB...   391  e-108
gi|11498934 cobalamin biosynthesis protein (cbiB) [Archaeoglobus...   232  3e-60
sp|Q58710|COBD_METJA PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COB...   202  4e-51
sp|O27460|COBD_METTH PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COB...   184  9e-46
gb|AAK43329.1| Cobalamin biosynthesis protein B (cbiB) [Sulfolob...   169  4e-41
emb|CAC11224.1| (AL445063) COBYRIC ACID SYNTHASE related protein...   167  2e-40
sp|Q52683|COBD_RHOCA COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|744...   152  4e-36
pir||S52223 hypothetical protein 945 - Rhodobacter capsulatus >g...   151  8e-36
emb|CAB40735.1| (AJ011317) CobD protein [Methylobacterium sp. CM4]    139  4e-32
dbj|BAB05307.1| (AP001512) cobalamin biosynthesis [Bacillus halo...   137  1e-31
sp|P21634|COBD_PSEDE COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|949...   137  2e-31
pir||A83486 cobalamin biosynthetic protein CobD PA1275 [imported...   135  7e-31
gi|10957439 cobalamin biosynthesis protein CobD, putative [Deino...   127  1e-28
sp|Q05600|CBIB_SALTY CBIB PROTEIN >gi|154421|gb|AAA27253.1| (L12...   126  3e-28
gb|AAG19854.1| (AE005070) Vng1578h [Halobacterium sp. NRC-1]          116  4e-25
sp|P74475|COBD_SYNY3 COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|744...   106  3e-22
sp|Q10518|COBD_MYCTU COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|744...    99  4e-20
emb|CAB59463.1| (AL132644) cobalamin biosynthesis protein [Strep...    93  4e-18
sp|Q9YAA0|COBD_AERPE PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COB...    93  4e-18
gb|AAG23557.1|AF244608_1 (AF244608) cobalamin biosynthesis prote...    73  3e-12

>pir||C75190 cobalamin biosynthesis protein B PAB0025 - Pyrococcus abyssi
           (strain Orsay) >gi|5457479|emb|CAB48970.1| (AJ248283)
           cobalamin biosynthesis protein B [Pyrococcus abyssi]
           Length = 290
           
 Score =  580 bits (1478), Expect = e-165
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV 60
           MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV
Sbjct: 1   MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV 60

Query: 61  ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSR 120
           ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSR
Sbjct: 61  ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSR 120

Query: 121 DVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDER 180
           DVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDER
Sbjct: 121 DVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDER 180

Query: 181 YEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKINSDKPIAAMSAVLGV 240
           YEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKINSDKPIAAMSAVLGV
Sbjct: 181 YEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKINSDKPIAAMSAVLGV 240

Query: 241 WLEKPGAYRFPGREPRDEDIKRALDVYKLVVAEYLSIVFVLKVVQLCLNP 290
           WLEKPGAYRFPGREPRDEDIKRALDVYKLVVAEYLSIVFVLKVVQLCLNP
Sbjct: 241 WLEKPGAYRFPGREPRDEDIKRALDVYKLVVAEYLSIVFVLKVVQLCLNP 290


>sp|O58114|COBD_PYRHO PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COBD
           >gi|7447318|pir||E71145 probable cobalamin biosynthesis
           protein D - Pyrococcus horikoshii
           >gi|3256767|dbj|BAA29450.1| (AP000002) 283aa long
           hypothetical cobalamin biosynthesis protein D
           [Pyrococcus horikoshii]
           Length = 283
           
 Score =  391 bits (994), Expect = e-108
 Identities = 189/274 (68%), Positives = 229/274 (82%), Gaps = 2/274 (0%)

Query: 9   LALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGK-IGFLAGAFVTFIIVALAFFLS 67
           LAL WDLLLGEPPA +HPVVWFGK+  F+D+ + RR   I FLAG F T ++++ AF LS
Sbjct: 6   LALGWDLLLGEPPAVVHPVVWFGKLIAFIDSHYSRRSPAIDFLAGLFATLVVLSFAFLLS 65

Query: 68  LIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSRDVKVLDL 127
           ++P Y  +PL+YLL++YLLKSSFAIRSLYEHV RT+ +D+EE RK VSMIVSRD   L  
Sbjct: 66  ILPLYAPYPLNYLLSVYLLKSSFAIRSLYEHVRRTMKDDVEEMRKEVSMIVSRDTSKLGR 125

Query: 128 AHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDERYEYFGKF 187
            HL SA+IESLAEN NDSVVAPLFY++LFGLPGA+VYRAVNTLDAM GYR  RYEYFGKF
Sbjct: 126 EHLISASIESLAENTNDSVVAPLFYYLLFGLPGALVYRAVNTLDAMVGYRTSRYEYFGKF 185

Query: 188 PARLDDILNFIPARLTVLLYLPFGV-KVLKYYKLARFKINSDKPIAAMSAVLGVWLEKPG 246
            ARLDDILNF+PAR+TVLL+LP    +V++YYK+ARFK+NSDKPIAAMSAVLG+WLEKP 
Sbjct: 186 SARLDDILNFLPARITVLLFLPLNPRRVIRYYKMARFKVNSDKPIAAMSAVLGIWLEKPN 245

Query: 247 AYRFPGREPRDEDIKRALDVYKLVVAEYLSIVFV 280
            YRFPGR+PR EDI+RAL VY +VV+E++ ++ +
Sbjct: 246 IYRFPGRDPRMEDIERALKVYVIVVSEWILLLLL 279


>gi|11498934 cobalamin biosynthesis protein (cbiB) [Archaeoglobus fulgidus]
           >gi|6225179|sp|O28933|COBD_ARCFU PROBABLE COBALAMIN
           BIOSYNTHESIS PROTEIN COBD >gi|7447320|pir||G69416
           cobalamin biosynthesis protein (cbiB) homolog -
           Archaeoglobus fulgidus >gi|2649237|gb|AAB89908.1|
           (AE001011) cobalamin biosynthesis protein (cbiB)
           [Archaeoglobus fulgidus]
           Length = 290
           
 Score =  232 bits (586), Expect = 3e-60
 Identities = 131/286 (45%), Positives = 177/286 (61%), Gaps = 8/286 (2%)

Query: 4   LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIVALA 63
           +++L   L+ D  +GEPPA +HPVVW+GK+   L+    R+  +    GAF   I++  A
Sbjct: 5   VVVLLTTLMLDAAVGEPPALLHPVVWYGKLISLLERAKFRKMLVEIFYGAFCCLIVITFA 64

Query: 64  FFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSRDVK 123
             LSL+P    +PL++L A+YLL SS +++S+  H    V   ++  RK V MIVSR+ +
Sbjct: 65  LILSLLP--FPYPLNFLWAVYLLFSSISVKSMVNHARVCVESGVD--RKAVQMIVSRNTE 120

Query: 124 VLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDERYEY 183
            L    L SA IES+AEN  D VVAPLFYF +FG+ GA+VYRAVNT DAM GYR  RYE 
Sbjct: 121 ELSEEQLCSAVIESVAENYVDGVVAPLFYFSIFGVAGAVVYRAVNTCDAMVGYRKGRYEA 180

Query: 184 FGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKINSDKPIAAMSAVLGVWLE 243
           FGKF ARLDDILN+IPARL++L +         Y      K+N    IAAMS +LGV LE
Sbjct: 181 FGKFAARLDDILNYIPARLSLLFFELLKRGAFSYGLKRNVKLNG-CAIAAMSYLLGVKLE 239

Query: 244 KPGAYRFPGREPRDEDIKRALDVY---KLVVAEYLSIVFVLKVVQL 286
           KPG Y  PG EP   DI+RA+  +    ++   + +I   +++V L
Sbjct: 240 KPGYYSLPGIEPSAADIERAIKAFVRLTVIAVIFTTIAVSIRIVLL 285


>sp|Q58710|COBD_METJA PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COBD
           >gi|2127814|pir||A64464 cobalamin biosynthesis protein D
           homolog - Methanococcus jannaschii
           >gi|1591953|gb|AAB99321.1| (U67571) cobalamin
           biosynthesis protein B (cbiB) [Methanococcus jannaschii]
           Length = 307
           
 Score =  202 bits (509), Expect = 4e-51
 Identities = 122/303 (40%), Positives = 181/303 (59%), Gaps = 28/303 (9%)

Query: 1   MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWR----RRGKIGFLAGAFVT 56
           +NP+IL  LA+I+D ++GE P  IHP VW GK+  FL+N ++    +     FL G+  T
Sbjct: 2   LNPIILF-LAIIFDRIIGELPESIHPTVWIGKLIAFLENIFKSTNCKNKYRDFLFGSLTT 60

Query: 57  FIIV----ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTV----TEDIE 108
           FI +     +AFF+      L FPL+Y++  +LL ++   +SL+E   + +      D+E
Sbjct: 61  FITLLVVGVIAFFVDKCIMLLPFPLNYIIYGFLLSTTIGYKSLFEFCKKPIEYIKNGDLE 120

Query: 109 EKRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVN 168
             RK V  IVSRD   LD  H+ SAA+ESL+EN+ DS++  LFY + FGLPGA VYRA+N
Sbjct: 121 GARKAVQHIVSRDASKLDKEHVLSAAVESLSENITDSIIGALFYAIFFGLPGAFVYRAIN 180

Query: 169 TLDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYL---PF---GVKVLKYYKLAR 222
           TLDAM GY++E+Y ++GK  ARLDDI NFIP+R+  +L +   PF    VK   Y  L  
Sbjct: 181 TLDAMIGYKNEKYLWYGKLAARLDDIANFIPSRIAGILLIITAPFYKGDVKKAIYGFLKE 240

Query: 223 F----KINSDKPIAAMSAVLGVWLEKPGAYRFPGREPRDEDIKRALDVYKLVVAEYLSIV 278
                  NS   +A ++  L + LEK G Y+    +    D++++L+ +K V  +Y  +V
Sbjct: 241 ANKVPSPNSGYTMATLANALNITLEKIGYYKLGSGK---IDVEKSLNAFKAV--DYTVVV 295

Query: 279 FVL 281
           F++
Sbjct: 296 FLI 298


>sp|O27460|COBD_METTH PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COBD
           >gi|7447313|pir||F69054 cobalamin biosynthesis protein B
           - Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2622521|gb|AAB85886.1| (AE000903) cobalamin
           biosynthesis protein B [Methanobacterium
           thermoautotrophicum]
           Length = 297
           
 Score =  184 bits (463), Expect = 9e-46
 Identities = 119/285 (41%), Positives = 163/285 (56%), Gaps = 24/285 (8%)

Query: 1   MNPLILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV 60
           M+ + +L LA+I DLL+GEPP ++HPVVW G         W R           +  I V
Sbjct: 1   MSEVSVLLLAVILDLLIGEPPHRLHPVVWMGSAV-----EWMRNILGNSRISGIILTIAV 55

Query: 61  ALAFFLSL-IPSYLTFPLDYLLAIYLLKSSFAIRSLYE---HVARTVTEDIEEKRKTVSM 116
           A  F L L + ++L  PL+ +++  LL +  +IR L      V  ++ EDIE+ R+ +SM
Sbjct: 56  AAPFTLPLFLINHLQDPLNLIISSILLSAVISIRMLVTSALEVGGSLKEDIEDARRKLSM 115

Query: 117 IVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGY 176
           +VSRD   L    + SAAIE+L EN+ DSV AP+FYF+L GLPGA +YR VNTLDAM GY
Sbjct: 116 LVSRDTTSLSDEQITSAAIETLTENITDSVTAPIFYFILLGLPGAFLYRVVNTLDAMVGY 175

Query: 177 RDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKI----------- 225
            D      G FPARLDDILN+IP+R+T +L +P  + +   ++   F+I           
Sbjct: 176 LDSENRDIGWFPARLDDILNYIPSRITGVLMVPAALLLGMNWR-GSFRILLRDARRTPSP 234

Query: 226 NSDKPIAAMSAVLGVWLEKPGAYRFPGREPRDE-DIKRALDVYKL 269
           NS   +AA +  L V LEKPG Y     +P D  D ++ LD  KL
Sbjct: 235 NSGFTMAAAAGALSVQLEKPGVYVL--GDPCDGLDNEKLLDAVKL 277


>gb|AAK43329.1| Cobalamin biosynthesis protein B (cbiB) [Sulfolobus solfataricus]
           Length = 305
           
 Score =  169 bits (423), Expect = 4e-41
 Identities = 105/288 (36%), Positives = 162/288 (55%), Gaps = 20/288 (6%)

Query: 4   LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRR--GKIGFLAGAFVTFIIVA 61
           L +L LALIWDL + EPP  IHPVVW GKI+  L   ++    G I ++       +I  
Sbjct: 2   LFILALALIWDLTISEPPIYIHPVVWTGKISEILIKPYKGYFYGVILWILSVLPPLLIFV 61

Query: 62  LAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSRD 121
               ++ IP YL      ++  + LK++F+I+ LY+ V +    D ++ R     IV RD
Sbjct: 62  YLPIVAEIPIYLKI----IILTFSLKTTFSIKMLYDIVTKGSRLD-DQARYYAQQIVRRD 116

Query: 122 VKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDERY 181
           +   +  H+ SA IESL E+  D + +P+F+F++FGL GAM+ R  NT+D+M GY+    
Sbjct: 117 LSKSEKGHIASALIESLFESTVDGITSPIFWFLIFGLIGAMLQRLANTMDSMVGYKTPEL 176

Query: 182 EYFGKFPARLDDILNFIPARLTVLLYLPFGV----------KVLKYYKLARFKINSDKPI 231
              G F A++D ILN+IPARLT ++ L  G+          K L+  K+    +N+  PI
Sbjct: 177 RKEGWFSAKIDTILNYIPARLTGMIMLIAGLILGLDVKQGWKALREAKME--SVNAKYPI 234

Query: 232 AAMSAVLGVWLEKPGAYRFP-GREPRDEDIKRALDVYKLVVAEYLSIV 278
           A  + +L V LEK G Y+   G  P ++DI++AL ++KL +  Y  ++
Sbjct: 235 AIAAGLLNVSLEKVGHYKVGFGNLPCEDDIEKALKLFKLSLILYFLVI 282


>emb|CAC11224.1| (AL445063) COBYRIC ACID SYNTHASE related protein [Thermoplasma
           acidophilum]
           Length = 304
           
 Score =  167 bits (418), Expect = 2e-40
 Identities = 104/299 (34%), Positives = 175/299 (57%), Gaps = 22/299 (7%)

Query: 4   LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIV--A 61
           +IL+G A+  D++ GEP   IHPVV+ GK++  ++  +R           F   +IV  A
Sbjct: 3   IILIG-AIAIDIIFGEPKEYIHPVVFSGKVSKRIETYFRHHDNRIVYGSIFAVAVIVITA 61

Query: 62  LAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTE-----DIEEKRKTVSM 116
           + +FL++  S     +  ++++ +LK++F+I ++ +H+ R V E     +I + R  +S 
Sbjct: 62  IPYFLAIYVSSFVLVIYVIVSMVILKTTFSISAMGDHI-RLVVESLKNGNISDARVYLSR 120

Query: 117 IVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGY 176
           +V RD   L+   ++SAAIE++AE L D  + PLF+F+  G+PGA V R +NTLD+M GY
Sbjct: 121 VVRRDTSNLNENEISSAAIETIAEGLVDGYMTPLFFFIFLGIPGAFVARIINTLDSMCGY 180

Query: 177 RDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYK--------LARF-KINS 227
           +D     FG+F A +D ++N+IPARL+   ++ F   VL Y          ++RF  +N+
Sbjct: 181 KDRENFEFGRFSAFMDTVINYIPARLS-WFFIGFSADVLNYRHKVISPRKYVSRFDSVNA 239

Query: 228 DKPIAAMSAVLGVWLEKPGAY--RFPGREPRDEDIKRALDVYKLVVAEYLSIVFVLKVV 284
             PI+ M+  L + LEK G+Y     G +P   DI+R++ V+ + V  Y +I+FVL ++
Sbjct: 240 GWPISTMACALNLRLEKRGSYIVNDEGYQPSVRDIERSMHVFYVAVYSY-TIIFVLPLL 297


>sp|Q52683|COBD_RHOCA COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447319|pir||T03524 cobD
           protein - Rhodobacter capsulatus
           >gi|3128325|gb|AAC16177.1| (AF010496) CobD protein
           [Rhodobacter capsulatus]
           Length = 314
           
 Score =  152 bits (381), Expect = 4e-36
 Identities = 105/311 (33%), Positives = 157/311 (49%), Gaps = 28/311 (9%)

Query: 1   MNPLILLGLALIWDLLLGEPPAKI----HPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVT 56
           MN   ++ +A+  DL LG P A      HPV W G +   L+  W  +G++  L G  V 
Sbjct: 1   MNFAAMMVVAIGIDLALGWPDALYKRIGHPVTWIGALIARLEKGWNFKGRLRRLRGVLVA 60

Query: 57  FIIVALAFFLSLIPSYLTFPLDY---LLAIYLLKSSFAIRSLYEHVART----VTEDIEE 109
             ++     ++L    L  P  +   L+   L     A+RS+++HVA      +  D+  
Sbjct: 61  LAVIGTTVVIALAVQ-LWLPAGWPGVLIGGILAWPFVALRSMHDHVAAVAKPLIAGDLPG 119

Query: 110 KRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNT 169
            R+ VSMIV RD   LD   +  AA+ESLAEN +D +VAPLF+  + GLPG   Y+A+NT
Sbjct: 120 ARQAVSMIVGRDPSQLDQPGVARAALESLAENSSDGIVAPLFWGCVAGLPGIAGYKAINT 179

Query: 170 LDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYL------PFGVKVLKYYKLARF 223
           LD+M G+R +RYE FG   AR+DD++N IPARLT L +          + V+     +  
Sbjct: 180 LDSMIGHRTDRYEEFGWASARIDDLVNLIPARLTGLFFALASPCRARALAVMARDARSHR 239

Query: 224 KINSDKPIAAMSAVLGVWLEKPGAY----------RFPGREPRDEDIKRALDVYKLVVAE 273
             N+  P AAM+  L V L  P  Y               +PR  D+ R L +Y+  +A 
Sbjct: 240 SPNAGWPEAAMAGALAVRLSGPRIYADRVANEPWLNGTAPDPRPADLARGLALYRRAMAG 299

Query: 274 YLSIVFVLKVV 284
              ++ ++ V+
Sbjct: 300 MTLVIGLVAVL 310


>pir||S52223 hypothetical protein 945 - Rhodobacter capsulatus
           >gi|609232|emb|CAA86581.1| (Z46611) (=ORF945)
           [Rhodobacter capsulatus]
           Length = 314
           
 Score =  151 bits (378), Expect = 8e-36
 Identities = 104/311 (33%), Positives = 157/311 (50%), Gaps = 28/311 (9%)

Query: 1   MNPLILLGLALIWDLLLGEPPAKI----HPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVT 56
           MN   ++ +A+  DL LG P A      HPV W  ++   L+  W  +G++  L G  V 
Sbjct: 1   MNFAAMMVVAIGIDLALGWPDALYKRIGHPVTWIARLIARLEKGWNFKGRLRRLRGVLVA 60

Query: 57  FIIVALAFFLSLIPSYLTFPLDY---LLAIYLLKSSFAIRSLYEHVART----VTEDIEE 109
             ++     ++L    L  P  +   L+   L     A+RS+++HVA      +  D+  
Sbjct: 61  LAVIGTTVVIALAVQ-LWLPAGWPGVLIGGILAWPFVALRSMHDHVAAVAKPLIAGDLPG 119

Query: 110 KRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNT 169
            R+ VSMIV RD   LD   +  AA+ESLAEN +D +VAPLF+  + GLPG   Y+A+NT
Sbjct: 120 ARQAVSMIVGRDPSQLDQPGVARAALESLAENSSDGIVAPLFWGCVAGLPGIAGYKAINT 179

Query: 170 LDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYL------PFGVKVLKYYKLARF 223
           LD+M G+R +RYE FG   AR+DD++N IPARLT L +          + V+     +  
Sbjct: 180 LDSMIGHRTDRYEEFGWASARIDDLVNLIPARLTGLFFALASPCRARALAVMARDARSHR 239

Query: 224 KINSDKPIAAMSAVLGVWLEKPGAY----------RFPGREPRDEDIKRALDVYKLVVAE 273
             N+  P AAM+  L V L  P  Y               +PR  D+ R L +Y+  +A 
Sbjct: 240 SPNAGWPEAAMAGALAVRLSGPRIYADRVANEPWLNGTAPDPRPADLARGLALYRRAMAG 299

Query: 274 YLSIVFVLKVV 284
              ++ ++ V+
Sbjct: 300 MTLVIGLVAVL 310


>emb|CAB40735.1| (AJ011317) CobD protein [Methylobacterium sp. CM4]
           Length = 330
           
 Score =  139 bits (347), Expect = 4e-32
 Identities = 112/313 (35%), Positives = 152/313 (47%), Gaps = 36/313 (11%)

Query: 4   LILLGLALIWDLLLGEPPAKI----HPVVWFGKIAGFLDNRWRRRGKIGF--LAGAFVTF 57
           LI+L LAL+ +   G P A      HPV W G++   LD R   RG+ G   L G     
Sbjct: 13  LIILALALLIEAAAGYPDALYRALGHPVTWIGRLIAALD-RGLNRGEPGARRLKGVLALL 71

Query: 58  IIVALA----FFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVT----EDIEE 109
           +++A A      L+ +       L  +LA  L  +  A RSL +HV R       E +  
Sbjct: 72  VLLAAATGAGLALTALAGLAGPVLGLVLAALLCATLPAQRSLDQHVIRVAAALRREGLPA 131

Query: 110 KRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNT 169
            R+ VSMIV RD + LD A +  AAIESLAEN +D +VAP F+  L GLPG ++Y+A NT
Sbjct: 132 GRRAVSMIVGRDPETLDEAAVCRAAIESLAENFSDGIVAPAFWIGLGGLPGGLLYKAANT 191

Query: 170 LDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLY-----LPFGVKVLKYYKLARFK 224
            D+M G+R  R+  FG   AR DD++N   +RLT LL      L  G      +   R  
Sbjct: 192 ADSMIGHRTPRHGAFGWAAARFDDLINLPASRLTALLIMAAARLTKGASARGAWAAVRRD 251

Query: 225 I------NSDKPIAAMSAVLGVWLEKPGAY---------RFPGR-EPRDEDIKRALDVYK 268
                  N+  P AAM+  LG+ L  P  Y            GR E   EDI+RA+ +Y+
Sbjct: 252 AGRHRSPNAGWPEAAMAGALGLRLAGPRVYGGERVTDSWMGDGRAEAGPEDIERAIRIYR 311

Query: 269 LVVAEYLSIVFVL 281
              A    +  +L
Sbjct: 312 TACALLFGLAAIL 324


>dbj|BAB05307.1| (AP001512) cobalamin biosynthesis [Bacillus halodurans]
           Length = 319
           
 Score =  137 bits (342), Expect = 1e-31
 Identities = 102/306 (33%), Positives = 155/306 (50%), Gaps = 28/306 (9%)

Query: 4   LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRW---RRRGKIGFLAGAFVTFIIV 60
           +I +  A I D  LG+P    HPVV  GK+  + + RW   R R + G L    V  I+ 
Sbjct: 6   VIAIVSAFILDKWLGDPKWLPHPVVGMGKLITYFERRWNCGRWRREKGVLLLLTVLLIVT 65

Query: 61  ALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYE---HVARTV-TEDIEEKRKTVSM 116
           AL+  L  +   +   L  ++   L+ S+ A + L E    VAR + T ++ E R+ +S 
Sbjct: 66  ALSLALVWLSYQVHLLLGVIVEALLIASTIAAKGLKEAAEEVARPLATRNLLEARRKLSY 125

Query: 117 IVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGY 176
           IV RD   LD   +   AIE++AEN +D V APLFY ++ G P A++YRA NT D+M GY
Sbjct: 126 IVGRDTDQLDEKEIARGAIETVAENTSDGVTAPLFYALIGGAPLALLYRATNTCDSMVGY 185

Query: 177 RDERYEYFGKFPARLDDILNFIPARLTVLLYL---------PFG--VKVLKYYKLARFKI 225
           ++ERY  FG   A+ DD+LN++P+R+T +L L         P G  +K+L          
Sbjct: 186 KNERYRDFGWASAKFDDVLNWVPSRITGVLMLLLHRKRRQAPLGQSLKMLAREAKKHPSP 245

Query: 226 NSDKPIAAMSAVLGVWLEKPGAYR----------FPGREPRDEDIKRALDVYKLVVAEYL 275
           NS    AAM+ +L V L     Y+          +  +    +DI  ++ +    V  +L
Sbjct: 246 NSGWGEAAMALLLHVTLGGTNTYQGMTSERAKMGYGTKAMTAKDIDESIAIMNRTVLGFL 305

Query: 276 SIVFVL 281
             +F+L
Sbjct: 306 VFLFLL 311


>sp|P21634|COBD_PSEDE COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|94951|pir||E36144 cobD
           protein - Pseudomonas sp >gi|151149|gb|AAA25776.1|
           (M59236) ORF 5 [Pseudomonas denitrificans]
           Length = 323
           
 Score =  137 bits (341), Expect = 2e-31
 Identities = 99/272 (36%), Positives = 141/272 (51%), Gaps = 28/272 (10%)

Query: 4   LILLGLALIWDLLLGEPP---AKI-HPVVWFGKIAGFLDNRWRRR----GKIGFLAGAFV 55
           L++L LAL+ D ++G+P    A++ HPVV+FGK  GF D R  R         F     +
Sbjct: 6   LLILALALVIDRVVGDPDWLWARVPHPVVFFGKAIGFFDARLNREDLEDSARKFRGVVAI 65

Query: 56  TFIIVALAFFLSLIPSYLTF--PLDYLLAIYLLKSSFAIRSLYEHVARTV----TEDIEE 109
             ++   A+F  L+        PL +LL   L+    A +SL +HV R         +E 
Sbjct: 66  LLLLGISAWFGHLLHRLFAVLGPLGFLLEAVLVAVFLAQKSLADHVRRVAGGLRQGGLEG 125

Query: 110 KRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNT 169
            R  VSMIV RD K LD   +  AAIESLAEN +D VVAP F++ + GLPG + Y+ +NT
Sbjct: 126 GRAAVSMIVGRDPKTLDEPAVCRAAIESLAENFSDGVVAPAFWYAVAGLPGLLAYKMLNT 185

Query: 170 LDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARFKI---- 225
            D+M G++  +Y +FG   ARLDD+ N   ARL++LL +  G  + +    A+  +    
Sbjct: 186 ADSMIGHKSPKYLHFGWASARLDDLANLPAARLSILL-ISAGALIHRGASAAKDALTVAL 244

Query: 226 ---------NSDKPIAAMSAVLGVWLEKPGAY 248
                    NS  P AAM+  L + L  P  Y
Sbjct: 245 RDHGLHRSPNSGWPEAAMAGALDLQLAGPRIY 276


>pir||A83486 cobalamin biosynthetic protein CobD PA1275 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9947209|gb|AAG04664.1|AE004557_5 (AE004557)
           cobalamin biosynthetic protein CobD [Pseudomonas
           aeruginosa]
           Length = 312
           
 Score =  135 bits (336), Expect = 7e-31
 Identities = 102/304 (33%), Positives = 152/304 (49%), Gaps = 37/304 (12%)

Query: 6   LLG-LALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIG------------FLAG 52
           LLG L ++ D   GEP    HP+V FG++A  L+ R+ R    G              A 
Sbjct: 4   LLGILGVVLDARFGEPQGW-HPLVAFGRLADRLERRFNRSRLAGEADPGVGWRSHGVTAW 62

Query: 53  AFVTFIIVALAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTE----DIE 108
                 +  LA+ L+ +P      L +L+    L ++  +RSL EH           D++
Sbjct: 63  VLAVLPLTLLAWALAELPY-----LGWLVQALALYAALGLRSLGEHAEPVALALRAGDLD 117

Query: 109 EKRKTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVN 168
           E R+ V  +VSRD + LD A +  AA ES+ EN +D+V A LF+F + G PG ++YR  N
Sbjct: 118 EARRRVGYLVSRDTRELDQAGVARAATESVLENGSDAVYAALFWFAVAGAPGVVLYRLSN 177

Query: 169 TLDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYLPFG-----VKVLKYYKLARF 223
           TLDAM+GYR+ R+E FG   A++DDILN++PARL  L Y   G     ++  +       
Sbjct: 178 TLDAMWGYRNARFERFGWAAAKIDDILNYLPARLVALTYALLGDTRQALRCWREQAPQWD 237

Query: 224 KINSDKPIAAMSAVLGVWLEKPGAYR---------FPGREPRDEDIKRALDVYKLVVAEY 274
             N+   +AA +  LGV+L     Y            G +P+  DI RAL + +  V  +
Sbjct: 238 SPNAGPVMAAGAGALGVFLGGAAIYHGELHQRPLLGSGPQPQGRDIYRALALVRQGVLLW 297

Query: 275 LSIV 278
           L ++
Sbjct: 298 LLVL 301


>gi|10957439 cobalamin biosynthesis protein CobD, putative [Deinococcus
           radiodurans] >gi|7473449|pir||B75619 probable cobalamin
           biosynthesis protein CobD - Deinococcus radiodurans
           (strain R1) >gi|6460868|gb|AAF12572.1|AE001826_41
           (AE001826) cobalamin biosynthesis protein CobD, putative
           [Deinococcus radiodurans]
           Length = 300
           
 Score =  127 bits (317), Expect = 1e-28
 Identities = 102/272 (37%), Positives = 135/272 (49%), Gaps = 19/272 (6%)

Query: 5   ILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRW-RRRGKIGFLAGAFVTFIIVALA 63
           +LL LAL     LGEPPA  HPV++ G    +    W  +  K  F  GA       AL 
Sbjct: 8   LLLALALD---TLGEPPAYFHPVIYMGNYLRWAQTHWCGKTAKQQFTQGAAGW----ALG 60

Query: 64  FFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTE----DIEEKRKTVSM-IV 118
             L+    +    L + +   LLK   A ++L++ VA         D+ E R+ ++  +V
Sbjct: 61  AGLAAGAGWTASGLPWWVQGALLKPLLARKALFDAVAEVAGALEQGDVPEARRLLAWHLV 120

Query: 119 SRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRD 178
           SRD   L  A +  AAIESLAENL+DSVVAPL  +   GLP A  YR  NT DAM+GYR 
Sbjct: 121 SRDTSQLTAAEVAGAAIESLAENLSDSVVAPLLAYRAGGLPLAAAYRLTNTADAMWGYRT 180

Query: 179 ERYEYFGKFPARLDDILNFIPARLTVLLYLPF-GVKVLKYYKLAR---FKINSDKPIAAM 234
              E  GK  A+ DD+ N  PARLT L  L   G +  + +   R      N+  P++A 
Sbjct: 181 PELEDAGKAAAKADDLFNLAPARLTALCTLMVSGSQSWRVWVRDRRNPASPNAGHPMSAF 240

Query: 235 SAVLGVWLEKPGAY--RFPGREPRDEDIKRAL 264
           +  LGV L+K G Y     G  P  E +  AL
Sbjct: 241 AGALGVRLDKRGVYVLNAAGAAPGPEHLAPAL 272


>sp|Q05600|CBIB_SALTY CBIB PROTEIN >gi|154421|gb|AAA27253.1| (L12006) putative
           [Salmonella typhimurium]
           Length = 319
           
 Score =  126 bits (314), Expect = 3e-28
 Identities = 86/262 (32%), Positives = 136/262 (51%), Gaps = 23/262 (8%)

Query: 9   LALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRR--GKIGFLAGAFVTFIIVA----- 61
           +A + D ++G+P    HPV W G++  F+    RR   G      G  V +++V      
Sbjct: 8   IAWVLDFIIGDPQHWPHPVRWIGRLITFVQRIVRRYCPGDKALRIGGGVMWVVVVGATWG 67

Query: 62  LAFFLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTE-----DIEEKRKTVSM 116
           +A+ +  +   +     + + ++++ ++ A RSL  H A+ V       D+ E R  +S 
Sbjct: 68  VAWGVLALAQRIHPWFGWSVEVWMIFTTLAGRSL-AHAAQEVERPLRKNDLAESRIKLSW 126

Query: 117 IVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGY 176
           IV RD   L  A +N A +E++AEN  D ++APLF+  L G P AM Y+AVNTLD+M GY
Sbjct: 127 IVGRDTSQLQPAQINRAVVETVAENTVDGIIAPLFFLFLGGAPLAMAYKAVNTLDSMVGY 186

Query: 177 RDERYEYFGKFPARLDDILNFIPARLT-VLLYLPFGVKVLKYYKLARF----KINSDKPI 231
           + E+Y   G   AR+DD+ N++PARL+ +LL +  G+  L  ++  R     + N   P 
Sbjct: 187 KHEKYRAIGMVSARMDDVANYLPARLSWLLLGIAAGLCRLSGWRALRIGWRDRYNHSSPN 246

Query: 232 AAMS-----AVLGVWLEKPGAY 248
            A S       LG+ L  P  Y
Sbjct: 247 CAWSEACVAGALGIQLGGPNNY 268


>gb|AAG19854.1| (AE005070) Vng1578h [Halobacterium sp. NRC-1]
           Length = 308
           
 Score =  116 bits (287), Expect = 4e-25
 Identities = 88/262 (33%), Positives = 127/262 (47%), Gaps = 23/262 (8%)

Query: 5   ILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIVALAF 64
           + +G+AL  D  + EPPA  HPV WFG+  G +D  W R   +G LA   +     A  +
Sbjct: 9   VAVGVAL--DAAIAEPPAGCHPVAWFGRAVGVVDRPWTRPLAVGALAAIALPLAAAATVW 66

Query: 65  FLSLIPSYLTFPLDYLLAIYLLKSSFAIRSLYEH----VARTVTED-IEEKRKTVSMIVS 119
               + ++ +     ++A  ++  + + R L       +A T TE+ ++  R+ +  +  
Sbjct: 67  AAVTVATWGSALAGAVVAGLVVFVTTSRRMLLAEASGVIAATRTENSLDAARRRLRALAG 126

Query: 120 RDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFML--------FGLPGAMVYRAVNTLD 171
           RD   L    L SAA+ES AENL D +VAPL  F +         G   A   +AVNTLD
Sbjct: 127 RDPDALSAGELRSAAVESTAENLADGLVAPLAAFAVGAAVVSLPVGAAAAAWVKAVNTLD 186

Query: 172 AMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLY-----LPFGVKVLKYYKLARFKIN 226
           +M GYR +R    G   ARLDD + ++PARL  +L       P  V        A    N
Sbjct: 187 SMLGYRSKR---VGTASARLDDAVMWVPARLAAVLIAATARAPAAVSRAAADAGAPPSPN 243

Query: 227 SDKPIAAMSAVLGVWLEKPGAY 248
           S  P+A ++AVL   L KPG Y
Sbjct: 244 SGWPMATLAAVLDCRLVKPGVY 265


>sp|P74475|COBD_SYNY3 COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447314|pir||S76447
           hypothetical protein - Synechocystis sp. (strain PCC
           6803) >gi|1653664|dbj|BAA18576.1| (D90915) CbiB protein
           [Synechocystis sp.]
           Length = 342
           
 Score =  106 bits (263), Expect = 3e-22
 Identities = 86/271 (31%), Positives = 134/271 (48%), Gaps = 26/271 (9%)

Query: 4   LILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRR---GKIGFLAGAFVTFIIV 60
           +I+LG + + D LLG+P +  HPV + G +  F      R+        L G F+   I+
Sbjct: 14  VIILGGSALLDFLLGDPKSWRHPVEFIGSVINFASQLIIRKVNDKNSRRLWGIFLGLKII 73

Query: 61  ALAFFLSLIPSYLTFPLDYLLAIYL----LKSSFAIRSLYEHVARTVTE-----DIEEKR 111
             + FL+ +  YL   +  +LA+ +    + S FA  SL +  A++V E     D+   R
Sbjct: 74  ISSGFLAWLIVYLAEKVSPVLAVIIQIIGVASCFAGHSLAQ-AAQSVIEPLKAGDLPTAR 132

Query: 112 KTVSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGL-------PGAMVY 164
           + +++ V RD   L    +  A +ES+AEN  D V +PLFY +L  L       P A+ Y
Sbjct: 133 QKLALFVGRDTNNLSEREILRATVESVAENTVDGVTSPLFYALLGILFPFVGPWPLAIAY 192

Query: 165 RAVNTLDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLKYYKLARF- 223
           +A +TLD+M GY+ E Y   G F ARL+D L ++P RLTV +      K  + + + R  
Sbjct: 193 KAASTLDSMVGYKREPYTDLGWFSARLEDYLTWLPCRLTVFMLAILSGKPKQTWAIVRRD 252

Query: 224 -----KINSDKPIAAMSAVLGVWLEKPGAYR 249
                  NS    A  +A+LG+ L     Y+
Sbjct: 253 GPLDPSPNSGWSEAIYAAILGIQLGGDNYYQ 283


>sp|Q10518|COBD_MYCTU COBALAMIN BIOSYNTHESIS PROTEIN COBD >gi|7447317|pir||H70777
           probable cobD - Mycobacterium tuberculosis (strain
           H37RV) >gi|1261938|emb|CAA94658.1| (Z70692) cobD
           [Mycobacterium tuberculosis]
           Length = 313
           
 Score = 99.5 bits (244), Expect = 4e-20
 Identities = 90/298 (30%), Positives = 134/298 (44%), Gaps = 42/298 (14%)

Query: 5   ILLGLALIWDLLLGEPPAKIHPVVWFGKIAGFLDNRWRRRGKIGFLAGAFVTFIIVALAF 64
           +L+G  L  D++ G+P  + HPV  FG+ A  L+    R G++   AGA    ++V    
Sbjct: 13  VLIGCLL--DVVFGDPK-RGHPVALFGRAAAKLEQITYRDGRV---AGAVHVGLLVGAVG 66

Query: 65  FLSL-----------IPSYLTFPLDYLLAIYLLKSSFAIRSLYEHVARTVTEDIEEKRKT 113
            L             + +  T     L    L ++   I  L E       +D+E  R+ 
Sbjct: 67  LLGAALQRLPGRSWPVAATATATWAALGGTSLARTGRQISDLLER------DDVEAARRL 120

Query: 114 VSMIVSRDVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAM 173
           +  +  RD   L    L  AA+ES+AEN  D+ V PL +    G+P  + YRA+NTLD+M
Sbjct: 121 LPSLCGRDPAQLGGPGLTRAALESVAENTADAQVVPLLWAASSGVPAVLGYRAINTLDSM 180

Query: 174 FGYRDERYEYFGKFPARLDDILNFIPARLTVLLYL---------PFG-VKVLKYYKLARF 223
            GYR  RY  FG   ARLDD  N++ AR T +L +         P G V+  +       
Sbjct: 181 IGYRSPRYLRFGWAAARLDDWANYVGARATAVLVVICAPVVGGSPRGAVRAWRRDAARHP 240

Query: 224 KINSDKPIAAMSAVLGVWLEKPGAYRF---------PGREPRDEDIKRALDVYKLVVA 272
             N+    AA +  L V L  P  Y            GR P+  D++RA+ + ++V A
Sbjct: 241 SPNAGVVEAAFAGALDVRLGGPTRYHHELQIRPTLGDGRSPKVADLRRAVVLSRVVQA 298


>emb|CAB59463.1| (AL132644) cobalamin biosynthesis protein [Streptomyces coelicolor
           A3(2)]
           Length = 327
           
 Score = 92.8 bits (227), Expect = 4e-18
 Identities = 74/206 (35%), Positives = 104/206 (49%), Gaps = 17/206 (8%)

Query: 11  LIWDLLLGEPPAKIHPVVWFGKIAGFLDN-RWRRRGKIGFL------AGAFVTFIIVALA 63
           L+ DLLLG+P  + HPV  FG+ AG ++   WR     G L       GA V     A A
Sbjct: 15  LLGDLLLGDP-RRGHPVAAFGRAAGAVERVLWRDHRGWGTLHTVVCAGGAAVLGSAAAHA 73

Query: 64  FFLSLIPSY-LTFPLDYLLA--IYLLKSSFAIRSLYEHVARTVTEDIEEKRKTVSMIVSR 120
              S   S  LT    + +     L + + AI    E        D+E  R  +  +  R
Sbjct: 74  VRRSSAASVALTAAATWSVVGGTSLAREATAIGRALE------AGDVEAARARLPHLCGR 127

Query: 121 DVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDER 180
           D + LD   +  A +ES+AEN +D+VV  L +  + G+PG + +RAVNTLDAM G++  R
Sbjct: 128 DPQALDADGIARAVVESVAENTSDAVVGALVWGAVAGVPGLLGFRAVNTLDAMVGHKSPR 187

Query: 181 YEYFGKFPARLDDILNFIPARLTVLL 206
           Y  +G   ARLDD+  +  ARLT +L
Sbjct: 188 YRRYGWASARLDDLAGWPGARLTAVL 213


>sp|Q9YAA0|COBD_AERPE PROBABLE COBALAMIN BIOSYNTHESIS PROTEIN COBD
           >gi|7447316|pir||A72508 probable cobalamin biosynthesis
           protein APE2039 - Aeropyrum pernix (strain K1)
           >gi|5105737|dbj|BAA81049.1| (AP000063) 323aa long
           hypothetical cobalamin biosynthesis protein [Aeropyrum
           pernix]
           Length = 323
           
 Score = 92.8 bits (227), Expect = 4e-18
 Identities = 74/203 (36%), Positives = 101/203 (49%), Gaps = 15/203 (7%)

Query: 68  LIPSYLTFPLDYLLAI-YLLKSSFAIRSLYEHVART----VTEDIEEKRKTVSMIVSRDV 122
           L  SYL  P  + LA+  ++K S  +R L +   +         +E  R+ V  IV RD+
Sbjct: 85  LAASYLVHPALHTLAVGVIVKLSMPLRLLLDTCIKASRMAAAGRVECSRRLVQGIVRRDL 144

Query: 123 KVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDERYE 182
               L  + SA IES AE+L D   +PL Y++L G  GA++ R  NTLD   G++     
Sbjct: 145 SGEPLGRVLSACIESTAESLVDGYTSPLTYYILLGPLGALLQRLSNTLDGAVGFKTPLLY 204

Query: 183 YFGKFPARLDDILNFIPARLT---VLLYLPF-GVKVLKYYK-LARF-----KINSDKPIA 232
             G F A+ D +LNFIPARLT   V L  P  G   L   + +AR       +N+  PI+
Sbjct: 205 RQGWFSAKADTLLNFIPARLTAVMVALAAPLAGASTLGSLRCIARCARLLESVNAGYPIS 264

Query: 233 AMSAVLGVWLEKPGAYRFPGREP 255
           A +  L V LEK G Y   G  P
Sbjct: 265 AFAGALDVRLEKKGFYIVNGGAP 287


>gb|AAG23557.1|AF244608_1 (AF244608) cobalamin biosynthesis protein CobD [Carboxydothermus
           hydrogenoformans]
           Length = 149
           
 Score = 73.4 bits (177), Expect = 3e-12
 Identities = 33/61 (54%), Positives = 45/61 (73%), Gaps = 1/61 (1%)

Query: 157 GLPGAMVYRAVNTLDAMFGYRDERYEYFGKFPARLDDILNFIPARLTVLLYLPFGVKVLK 216
           GLPG   YR VNTLD+M GY+ ERY YFG+  A+LDD+LN++PAR+T +L +     +L+
Sbjct: 3   GLPGVWFYRTVNTLDSMVGYKSERYLYFGRIAAKLDDLLNYLPARITGVL-MVLAAFILR 61

Query: 217 Y 217
           Y
Sbjct: 62  Y 62


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.328    0.146    0.437 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103805003
Number of Sequences: 2977
Number of extensions: 4106562
Number of successful extensions: 14187
Number of sequences better than 1.0e-10: 21
Number of HSP's better than  0.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 14127
Number of HSP's gapped (non-prelim): 23
length of query: 290
length of database: 189,106,746
effective HSP length: 51
effective length of query: 239
effective length of database: 158,583,909
effective search space: 37901554251
effective search space used: 37901554251
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 165 (68.7 bits)