BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0026 (hisC) DE:histidinol-phosphate aminotransferase (hisC)
(329 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75190 histidinol-phosphate aminotransferase (hisc) PAB0026... 666 0.0
pir||F71145 probable histidinol-phosphate aminotransferase - Pyr... 483 e-136
gi|11499584 histidinol-phosphate aminotransferase (hisC-1) [Arch... 134 1e-30
gi|11499606 histidinol-phosphate aminotransferase (hisC-2) [Arch... 130 2e-29
sp|Q58365|HIS8_METJA PROBABLE HISTIDINOL-PHOSPHATE AMINOTRANSFER... 118 1e-25
gb|AAG19443.1| (AE005037) histidinol-phosphate transaminase; His... 113 4e-24
sp|P17736|HIS8_HALVO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 112 5e-24
gb|AAG19857.1| (AE005070) histidinol-phosphate transaminase; His... 104 1e-21
pir||T50821 histidinol-phosphate aminotransferase-like protein -... 101 1e-20
pir||T03270 probable histidinol-phosphate transaminase (EC 2.6.1... 100 2e-20
dbj|BAB05308.1| (AP001512) aminotransferase (cobalamin biosynthe... 100 2e-20
pir||F83250 histidinol-phosphate aminotransferase PA3165 [import... 100 4e-20
pir||G72304 histidinol-phosphate aminotransferase - Thermotoga m... 98 1e-19
sp|O27624|HIS8_METTH PROBABLE HISTIDINOL-PHOSPHATE AMINOTRANSFER... 98 2e-19
pir||T36050 probable histidinol-phophate aminotransferase - Stre... 96 4e-19
gb|AAC79515.1| (U90625) CobD [Salmonella typhimurium] 96 6e-19
sp|O07131|HIS8_METFL HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 96 7e-19
gi|10957440 histidinol-phosphate aminotransferase [Deinococcus r... 94 3e-18
sp|Q57004|YB66_HAEIN PROBABLE AMINOTRANSFERASE HI1166 >gi|107420... 93 4e-18
sp|P17731|HIS8_BACSU HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 90 2e-17
pir||E70478 histidinol-phosphate aminotransferase - Aquifex aeol... 90 3e-17
dbj|BAB05384.1| (AP001512) histidinol-phosphate aminotransferase... 90 3e-17
pir||T45247 probable histidinol-phosphate transaminase (EC 2.6.1... 90 4e-17
pir||H70694 probable histidinol-phosphate aminotransferase - Myc... 90 4e-17
gb|AAD47361.1|AF038578_4 (AF038578) imidazole acetol phosphate a... 89 9e-17
pir||A81451 probable histidinol-phosphate transaminase (EC 2.6.1... 87 3e-16
emb|CAB62740.1| (AL133423) putative aminotransferase [Streptomyc... 87 4e-16
sp|O06591|HIS8_MYCTU HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 85 8e-16
sp|P10369|HIS8_SALTY HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 83 4e-15
sp|P16246|HIS8_STRCO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 82 9e-15
sp|Q9ZHE5|HIS8_BUCAP HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 82 1e-14
gb|AAK41178.1| Aspartate aminotransferase (aspB-2) [Sulfolobus s... 80 5e-14
sp|P14909|AAT_SULSO ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 80 5e-14
pir||S45613 aspartate aminotransferase - Sulfolobus solfataricus 80 5e-14
emb|CAA96498.1| (Z71971) hypothetical protein [Paracoccus denitr... 78 1e-13
pir||S77354 histidinol-phosphate aminotransferase hisC-1 - Synec... 78 1e-13
pir||D81289 probable aminotransferase Cj1436c [imported] - Campy... 78 1e-13
emb|CAC11142.1| (AJ250581) NikT protein [Streptomyces tendae] 78 1e-13
sp|P06986|HIS8_ECOLI HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 78 2e-13
sp|P34037|HIS8_ZYMMO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 78 2e-13
dbj|BAA77744.1| (AB008676) histidinol-phosphate aminotransferase... 77 2e-13
pir||XNEBHC histidinol-phosphate transaminase (EC 2.6.1.9) - Sal... 76 4e-13
gi|6322075 histidinol-phosphate aminotransferase; His5p [Sacchar... 76 4e-13
emb|CAA27150.1| (X03416) hisC protein [Escherichia coli] >gi|417... 75 9e-13
sp|P55683|Y4WE_RHISN PROBABLE AMINOTRANSFERASE Y4WE >gi|2182694|... 75 2e-12
emb|CAA29139.1| (X05650) HIS5 (AA 1-384) [Saccharomyces cerevisi... 74 3e-12
gi|11499943 aspartate aminotransferase (aspB-1) [Archaeoglobus f... 74 3e-12
gb|AAC05838.1| (AF052516) hemolysin erythrocyte lysis protein 2 ... 73 5e-12
pir||G75271 histidinol-phosphate aminotransferase - Deinococcus ... 73 5e-12
gb|AAK40774.1| Histidinol-phosphate aminotransferase, putative (... 72 1e-11
gb|AAK41425.1| Aspartate aminotransferase (aspB-3) [Sulfolobus s... 71 1e-11
dbj|BAA75925.1| (AB012002) aspartate aminotransferase [Pyrococcu... 71 1e-11
emb|CAC11170.1| (AL445063) histidinol-phosphate aminotransferase... 71 2e-11
sp|P44423|HIS8_HAEIN HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 70 3e-11
pir||E71125 probable aromatic-amino-acid transaminase (EC 2.6.1.... 70 3e-11
pir||E72507 probable histidinol-phosphate aminotransferase APE20... 70 3e-11
sp|P36605|HIS8_SCHPO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 69 5e-11
gb|AAF61216.1| (AF224501) putative aminotransferase [Streptomyce... 69 7e-11
sp|P57202|HIS8_BUCAI HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 69 7e-11
>pir||D75190 histidinol-phosphate aminotransferase (hisc) PAB0026 - Pyrococcus
abyssi (strain Orsay) >gi|5457480|emb|CAB48971.1|
(AJ248283) histidinol-phosphate aminotransferase (hisC)
[Pyrococcus abyssi]
Length = 329
Score = 666 bits (1699), Expect = 0.0
Identities = 329/329 (100%), Positives = 329/329 (100%)
Query: 1 MLKPVRFSTHHGGARRNEIKLIDFSASVNPYPPEWVDEMFKRAREISFSYPYYEELEDEL 60
MLKPVRFSTHHGGARRNEIKLIDFSASVNPYPPEWVDEMFKRAREISFSYPYYEELEDEL
Sbjct: 1 MLKPVRFSTHHGGARRNEIKLIDFSASVNPYPPEWVDEMFKRAREISFSYPYYEELEDEL 60
Query: 61 SELLNEEITITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPE 120
SELLNEEITITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPE
Sbjct: 61 SELLNEEITITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPE 120
Query: 121 KLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSP 180
KLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSP
Sbjct: 121 KLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSP 180
Query: 181 EGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSVRMPWSIGSTGVAFLEFLIEDNFEHL 240
EGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSVRMPWSIGSTGVAFLEFLIEDNFEHL
Sbjct: 181 EGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSVRMPWSIGSTGVAFLEFLIEDNFEHL 240
Query: 241 RKTMPLIWQEKERIEKALNVKSDANFFIKYVGDAKKAVEELKKRGILVRDCTSFGLPGYI 300
RKTMPLIWQEKERIEKALNVKSDANFFIKYVGDAKKAVEELKKRGILVRDCTSFGLPGYI
Sbjct: 241 RKTMPLIWQEKERIEKALNVKSDANFFIKYVGDAKKAVEELKKRGILVRDCTSFGLPGYI 300
Query: 301 RFSVRRAEENERLVQALKDLSPELLAPVH 329
RFSVRRAEENERLVQALKDLSPELLAPVH
Sbjct: 301 RFSVRRAEENERLVQALKDLSPELLAPVH 329
>pir||F71145 probable histidinol-phosphate aminotransferase - Pyrococcus
horikoshii >gi|3256768|dbj|BAA29451.1| (AP000002) 328aa
long hypothetical histidinol-phosphate aminotransferase
[Pyrococcus horikoshii]
Length = 328
Score = 483 bits (1231), Expect = e-136
Identities = 227/320 (70%), Positives = 272/320 (84%), Gaps = 2/320 (0%)
Query: 1 MLKPVRFSTHHGGARRNEIKLIDFSASVNPYPPEWVDEMFKRAREISFSYPYYEELEDEL 60
+++P+ F HGGAR+ LIDFSASVNPYPPEW+ E+F+RA+++S Y YYEELE+E
Sbjct: 11 LMRPLNFKVIHGGARKEG--LIDFSASVNPYPPEWLSEVFERAKDLSSRYIYYEELEEEF 68
Query: 61 SELLNEEITITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPE 120
L+ E ITITAGITE LYLLGIL LR ++VIIP HTYGEYER+AR+F AK+IKG N+P
Sbjct: 69 ESLIGEPITITAGITEALYLLGILTLRNKRVIIPNHTYGEYERIARMFGAKVIKGPNDPS 128
Query: 121 KLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSP 180
KLAELVE SVV FCNPNNPDG+YYTP+ELK LIDAV D +LL+LDEAFIDFVK AKSP
Sbjct: 129 KLAELVERESVVLFCNPNNPDGKYYTPKELKSLIDAVTDTNSLLILDEAFIDFVKKAKSP 188
Query: 181 EGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSVRMPWSIGSTGVAFLEFLIEDNFEHL 240
GEN++KLRTFTKSYG+PGIR+GY+IGF +AFRSVRMPW+IG+ GVAFLE +IED F HL
Sbjct: 189 SGENLIKLRTFTKSYGVPGIRIGYVIGFSEAFRSVRMPWNIGAVGVAFLEKVIEDEFAHL 248
Query: 241 RKTMPLIWQEKERIEKALNVKSDANFFIKYVGDAKKAVEELKKRGILVRDCTSFGLPGYI 300
R+T+PLIW+EKERIE+ L VKSDANFFI VGDA+ VE+LKK+GILVRDC+SFGLP YI
Sbjct: 249 RRTLPLIWREKERIERRLGVKSDANFFIMNVGDARAVVEKLKKKGILVRDCSSFGLPNYI 308
Query: 301 RFSVRRAEENERLVQALKDL 320
RFSVR+ EEN++L++AL L
Sbjct: 309 RFSVRKPEENDKLIEALTSL 328
>gi|11499584 histidinol-phosphate aminotransferase (hisC-1) [Archaeoglobus
fulgidus] >gi|7450421|pir||A69500 histidinol-phosphate
aminotransferase (hisC-1) homolog - Archaeoglobus
fulgidus >gi|2648534|gb|AAB89251.1| (AE000964)
histidinol-phosphate aminotransferase (hisC-1)
[Archaeoglobus fulgidus]
Length = 319
Score = 134 bits (335), Expect = 1e-30
Identities = 94/321 (29%), Positives = 165/321 (51%), Gaps = 26/321 (8%)
Query: 21 LIDFSASVNPYPPE-WVDEMFKRAREIS-FSYPYYEELEDELSELLN---EEITITAGIT 75
++ +++ NPY P E F+ ++ + P Y EL +++S+ + + + AGI
Sbjct: 1 MVKLASNENPYGPSPKAIEAFRSYSDLHIYPNPEYRELREKISDYTGWDADRVVVGAGI- 59
Query: 76 EGLY--LLGILALRGRKVIIPRHTYGEYERVARIFNAKII---KGSN---EPEKLAELVE 127
+G+ L IL G +V+IP T+ Y + ++ K + +G N + + +
Sbjct: 60 DGILETLFRILIDEGDEVVIPIPTFPYYHILTKLSCGKEVLVRRGENYRIDESIFDAITQ 119
Query: 128 NNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPEGENIVK 187
++ CNPNNP G + K + + V AL+ LDEA+++F + S + EN+V
Sbjct: 120 KTKIILICNPNNPTGN---AEDAKLIEELVNSTNALIFLDEAYVEFSDVSFSVDAENVVI 176
Query: 188 LRTFTKSYGLPGIRVGYII---GFRDAFRSVRMPWSIGSTGVAFLEFLIEDNFEHLRKTM 244
RTF+K++GL +R+GY + FR+ P+ + + E ++D E +R +
Sbjct: 177 ARTFSKAFGLANLRIGYALLPEWLVSPFRAAMTPFPLSTPAAKAAEAALDD-VEWMRSCV 235
Query: 245 PLIWQEKERIEKALNVKSDANF----FIKYVGDAKKAVEELKKRGILVRDCTSF-GLPGY 299
I E+ER+ K L + N F+ + + EEL KRG++VRDC+SF G +
Sbjct: 236 GRIKAERERLYKELKKLVEVNLSQANFLFFESPVENLAEELLKRGVIVRDCSSFVGCGNH 295
Query: 300 IRFSVRRAEENERLVQALKDL 320
IR +V R EEN+ ++ALK++
Sbjct: 296 IRVTVGRPEENDMFLEALKEV 316
>gi|11499606 histidinol-phosphate aminotransferase (hisC-2) [Archaeoglobus
fulgidus] >gi|7450423|pir||G69502 histidinol-phosphate
aminotransferase (hisC-2) homolog - Archaeoglobus
fulgidus >gi|2648510|gb|AAB89229.1| (AE000963)
histidinol-phosphate aminotransferase (hisC-2)
[Archaeoglobus fulgidus]
Length = 342
Score = 130 bits (324), Expect = 2e-29
Identities = 105/331 (31%), Positives = 177/331 (52%), Gaps = 42/331 (12%)
Query: 20 KLIDFSASVNPYPP-EWVDEMFKRAREISFSYPY--YEELEDELSELLN---EEITITAG 73
++++ S++ NPY P E V E + RA + YP Y L+ L+E E I + G
Sbjct: 24 EVVNLSSNENPYEPSEEVREAYLRAVKYIPRYPKADYARLKKALAEYTGFEVENIAVGCG 83
Query: 74 ITEGLYLL-GILALRGRKVIIPRHTYGEYERVARIFNAKI----IKGSN-EPEKLAELVE 127
+E + + +L +V+IP +Y Y A + +A I +G +P+ +AE E
Sbjct: 84 ASELISCICNVLLEELDRVVIPMPSYTLYSIYAMLRSASISFPVFEGYRVDPDVIAE--E 141
Query: 128 NNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSP---EGEN 184
+VF C+PNNP G + + ++ V + +VLDEA+++F D+K + N
Sbjct: 142 RPKLVFLCSPNNPTGNSLS----REIVQKVAESAEYVVLDEAYVEFSDDSKIEMVRDYNN 197
Query: 185 IVKLRTFTKSYGLPGIRVGYII---GFRDAFRSVRMPWSIG----STGVAFLEFLIEDNF 237
++ LR+F+K +GL G+RVGY + +A VR+P+ I T +A L L
Sbjct: 198 LIVLRSFSKFFGLAGMRVGYAVCSAEIAEAIEKVRLPFGISYPAVETAIAALRSL----- 252
Query: 238 EHLRKTMPLIWQEKER-IEKALNVK------SDANFFIKYVGDAKKAVEELKKRGILVRD 290
++ +K I +E+ER IEK ++ SDAN F+ + + VE+L ++G +VRD
Sbjct: 253 DYYKKVRDRIVRERERLIEKLKEIEWLEVYPSDAN-FVLVKANKEGVVEKLAEKGFIVRD 311
Query: 291 CTSFGLPG-YIRFSVRRAEENERLVQALKDL 320
+ GL G YIR +V + E+N+RL++AL+++
Sbjct: 312 ASVMGLEGLYIRITVGKREDNDRLIEALREI 342
>sp|Q58365|HIS8_METJA PROBABLE HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE
ACETOL-PHOSPHATE TRANSAMINASE) >gi|2127971|pir||C64419
histidinol-phosphate transaminase (EC 2.6.1.9) -
Methanococcus jannaschii >gi|1591622|gb|AAB98960.1|
(U67539) histidinol-phosphate aminotransferase (hisC)
[Methanococcus jannaschii]
Length = 373
Score = 118 bits (292), Expect = 1e-25
Identities = 103/342 (30%), Positives = 166/342 (48%), Gaps = 52/342 (15%)
Query: 21 LIDFSASVNPYPP------EWVDEMFKRAREISFSYPYYEELEDELSELLN--EEITITA 72
+I ++ NP+ P + +DE+ K + + P L ELS+ LN EE I
Sbjct: 40 IIKLGSNENPWGPSPKIKEKILDEIDKIHQ---YPEPVNPILMKELSKFLNVDEENIIVG 96
Query: 73 GITEGLYLLGILAL---RGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPEK-------- 121
G + I G +VIIP T+ +Y A I NAKI + EK
Sbjct: 97 GDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVES 156
Query: 122 -LAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDA--- 177
L + + V+F C PNNP G R+++ +I+ + AL+V+D A+I++ K
Sbjct: 157 VLNNITDKTKVIFLCTPNNPTGNIIENRDVERVINETD---ALVVIDHAYIEYAKKEYDW 213
Query: 178 --KSPEGENIVKLRTFTKSYGLPGIRVG----------YIIGFRDAFRSVRMPWSIGSTG 225
K+PE +N++ LRTF+K +GL G+RVG Y++ + F R+ T
Sbjct: 214 TQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSLTRLSQVCAITA 273
Query: 226 V---AFLEFLIEDNFEHLRKTMPLIWQEKERIEKALNVKSDANFFIKYVG--DAKKAVEE 280
+ F E + D K+ +++ ++ + S+AN+ + + AK+ EE
Sbjct: 274 LRDREFFERCVRDGI----KSREMLYNGLKKFKDIKVYPSEANYLLVELKTMKAKEFCEE 329
Query: 281 LKKRGILVRDCTSF-GL-PGYIRFSVRRAEENERLVQALKDL 320
L KRG++VRDCTSF GL Y+R S+ EE ER ++ L+++
Sbjct: 330 LLKRGVIVRDCTSFDGLGDNYVRVSIGTFEEVERFLKILEEI 371
>gb|AAG19443.1| (AE005037) histidinol-phosphate transaminase; HisC1 [Halobacterium
sp. NRC-1]
Length = 395
Score = 113 bits (279), Expect = 4e-24
Identities = 81/264 (30%), Positives = 131/264 (48%), Gaps = 37/264 (14%)
Query: 88 GRKVIIPRHTYGEYERVARIFNAKIIK-----GSNEPEKLAELV----ENNSVVFFCNPN 138
G V++P + Y AR + + + G++ E A+ V + VV+ P+
Sbjct: 135 GDSVLVPSPGFTYYGMSARFHHGNVAEYDVAEGADGFEMTADAVVDAYDGERVVYLTTPH 194
Query: 139 NPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKS-------PEG-----ENIV 186
NP G +T E+ + D D L+++DEA+ +F + + P G ++I
Sbjct: 195 NPTGARFTLDEIVAVADRT-DEDTLVLVDEAYGEFTETPSAVTLFDGQPAGGHAPRDDIA 253
Query: 187 KLRTFTKSYGLPGIRVGYII---GFRDAFRSVRMPWSIG----STGVAFLEFLIEDNFEH 239
LRTF+K+YGL GIR+GY + + DA+ V+ P++ GVA L D+ +H
Sbjct: 254 VLRTFSKAYGLAGIRLGYAVVPDSWADAYARVQTPFAASVIACQAGVAAL-----DDDDH 308
Query: 240 LRKTMPLIWQEKERIEKALNVK---SDANFFIKYVGDAKKAVEELKKRGILVRDCTSFGL 296
+ T + ++ I L + S NF + VGDA + E K+ G+LVRDCTSFGL
Sbjct: 309 VEATTDSVAWGRDYIHDELAARTYESHGNFVLANVGDAGRVAEAAKREGVLVRDCTSFGL 368
Query: 297 PGYIRFSVRRAEENERLVQALKDL 320
P ++R ++ E ER V L ++
Sbjct: 369 PEHVRITIGTRSETERAVAVLNEV 392
>sp|P17736|HIS8_HALVO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|99227|pir||A35397 histidinol-phosphate
transaminase (EC 2.6.1.9) - Haloferax volcanii
>gi|148784|gb|AAA72824.1| (M33161)
histidinol-phosphate-aminotransferase (hisC) (EC
2.6.1.9) [Haloferax volcanii]
Length = 361
Score = 112 bits (278), Expect = 5e-24
Identities = 90/330 (27%), Positives = 162/330 (48%), Gaps = 29/330 (8%)
Query: 21 LIDFSASVNPY--PPEWVDEMFKRAREISFSYPY--YEELEDELSE---LLNEEITITAG 73
L S++ NP+ P+ V + A +S YP + +L + L++ L E++ ++ G
Sbjct: 32 LTKLSSNENPHGPSPKAVAAIEDAAPTVSV-YPKTAHTDLTERLADKWGLAPEQVWVSPG 90
Query: 74 ITEGL-YLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIK----GSNEPEKLAELV-- 126
+ YL + +++ P + Y AR + ++ ++ E+ A+LV
Sbjct: 91 ADGSIDYLTRAVLEPDDRILEPAPGFSYYSMSARYHHGDAVQYEVSKDDDFEQTADLVLD 150
Query: 127 --ENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKS----P 180
+ +V+ P+NP G EL L ++VE+ LLV+DEA+ +F ++ +
Sbjct: 151 AYDGERMVYLTTPHNPTGSVLPREELVELAESVEEH-TLLVVDEAYGEFAEEPSAIDLLS 209
Query: 181 EGENIVKLRTFTKSYGLPGIRVGYII---GFRDAFRSVRMPWSIGSTGVAFLEFLIEDNF 237
E +N+ LRTF+K+YGL G+R+GY + DA+ V P++ ++D
Sbjct: 210 EYDNVAALRTFSKAYGLAGLRIGYACVPEAWADAYARVNTPFAASEVACRAALAALDDE- 268
Query: 238 EHLRKTMPLIWQEKERIEKALNV---KSDANFFIKYVGDAKKAVEELKKRGILVRDCTSF 294
EH+ K++ ++ + + L+ +S+ NF + VGDA E ++ G++VRDC SF
Sbjct: 269 EHVEKSVESARWSRDYLREHLDAPTWESEGNFVLVEVGDATAVTEAAQREGVIVRDCGSF 328
Query: 295 GLPGYIRFSVRRAEENERLVQALKDLSPEL 324
GLP IR S + +R V L + E+
Sbjct: 329 GLPECIRVSCGTETQTKRAVDVLNRIVSEV 358
>gb|AAG19857.1| (AE005070) histidinol-phosphate transaminase; HisC2 [Halobacterium
sp. NRC-1]
Length = 336
Score = 104 bits (257), Expect = 1e-21
Identities = 92/330 (27%), Positives = 153/330 (45%), Gaps = 27/330 (8%)
Query: 11 HGGARRNEIKLIDFSASVNPYPPE-----WVDEMFKRAREISFSYPYYEELEDELSELLN 65
HGG+ ++ ++DFSA+ P P + + AR YP + + +
Sbjct: 14 HGGS--DDPDVLDFSANTTPRTPPGTRAAYAAALDDAARYPDDDYPAFRAAAADHVDCAR 71
Query: 66 EEITITAGITEGLYL-LGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPEKLAE 124
+ + T G G+ L + G V++P ++ EY R + A + ++ A+
Sbjct: 72 DTVVQTPGGLAGIRLAIETRVTPGDTVLVPAPSFSEYAREVELQGATPVFVPHDALLDAD 131
Query: 125 LVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPEGE- 183
E+ ++ C PNNP G Y L+ L++DEAF+ F DA S G
Sbjct: 132 PSEH-TLAIACTPNNPTGDRYDDDALRAFAARCRAANTELLVDEAFLGFT-DAPSIAGTP 189
Query: 184 NIVKLRTFTKSYGLPGIRVGYIIGFRD---AFRSVRMPWSIGSTGVAFLEFLIEDNFEHL 240
+V R+ TK +GLPG+R G+++ D R+ R W++G+ A + + E +
Sbjct: 190 GVVVARSLTKLFGLPGLRAGFLVAVGDRLTTLRTARRTWNLGAPAAAVGAHAMRQS-EFV 248
Query: 241 RKTMPLIWQEKERIEKALN-----VKSDANFFIKYVG----DAKKAVEELKKRGILVRDC 291
+T + E+ R+ AL+ S A F + VG DA A + GI +RD
Sbjct: 249 AETRRHVASERARMRAALSDAFDVHPSSAPFLLLDVGPRPVDAVMAAASAE--GIRLRDA 306
Query: 292 TSF-GLPGYIRFSVRRAEENERLVQALKDL 320
T+F GL ++R +VR +EN+RL+ AL D+
Sbjct: 307 TTFRGLDSHVRVAVRTPDENDRLLAALADV 336
>pir||T50821 histidinol-phosphate aminotransferase-like protein - Arabidopsis
thaliana >gi|6978917|gb|AAF34309.1| (AC021665) putative
histidinol-phosphate aminotransferase; 39506-41337
[Arabidopsis thaliana] >gi|8953414|emb|CAB96689.1|
(AL360334) histidinol-phosphate aminotransferase-like
protein [Arabidopsis thaliana]
Length = 415
Score = 101 bits (249), Expect = 1e-20
Identities = 98/330 (29%), Positives = 155/330 (46%), Gaps = 40/330 (12%)
Query: 21 LIDFSASVNPYPPEWVDEMFKRAREISFSYPYYEELEDELSE---LLNEEITITAGITEG 77
++ A+ NPY P + + P L D L++ L +E I + G E
Sbjct: 91 IVKLDANENPYGPPPEATLGNMKFPYVYPDPQSRRLRDALAQDSGLESEYILVGCGADEL 150
Query: 78 LYLLGILALR-GRKVIIPRHTYGEYERVARIFNAKIIKGSNEPE------KLAELVE--N 128
+ L+ L G K+I T+ Y A + A +IK P+ ++AE+VE
Sbjct: 151 IDLIMRCVLDPGEKIIDCPPTFSMYVFDAAVNGAGVIKVPRNPDFSLNVDRIAEVVELEK 210
Query: 129 NSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDF------VKDAKSPEG 182
+F +PNNPDG + +L +++ L+VLDEA+I+F +K K +
Sbjct: 211 PKCIFLTSPNNPDGSIISEDDLLKILEM----PILVVLDEAYIEFSGVESRMKWVK--KY 264
Query: 183 ENIVKLRTFTKSYGLPGIRVGY---IIGFRDAFRSVRMPWSIGSTG-VAFLEFLIEDNFE 238
EN++ LRTF+K GL G+RVGY + + + P+++ G VA L L N +
Sbjct: 265 ENLIVLRTFSKRAGLAGLRVGYGAFPLSIIEYLWRAKQPYNVSVAGEVAALAAL--SNGK 322
Query: 239 HLRKTMPLIWQEKERIEKALN-------VKSDANFFIKYVG---DAKKAVEELKKRGILV 288
+L + +E+ER+ L S +NF + V DAKK E+L K G++V
Sbjct: 323 YLEDVRDALVRERERLFGLLKEVPFLNPYPSYSNFILCEVTSGMDAKKLKEDLAKMGVMV 382
Query: 289 RDCTSFGLPGYIRFSVRRAEENERLVQALK 318
R S L GY+R S + E + L++ LK
Sbjct: 383 RHYNSQELKGYVRVSAGKPEHTDVLMECLK 412
>pir||T03270 probable histidinol-phosphate transaminase (EC 2.6.1.9) - common
tobacco >gi|3355626|emb|CAA70403.1| (Y09204)
histidinol-phosphate aminotransferase [Nicotiana
tabacum]
Length = 413
Score = 100 bits (247), Expect = 2e-20
Identities = 101/334 (30%), Positives = 154/334 (45%), Gaps = 46/334 (13%)
Query: 21 LIDFSASVNPY--PPEWVDEMFKRAREISFSYPYYEE--LEDELSE---LLNEEITITAG 73
++ A+ NPY PPE ++ + A + + YP E L L+E L +E I G
Sbjct: 87 IVKLDANENPYGPPPEVIEAL--GAMKFPYIYPDPESRTLRAALAEDSGLESEYILAGCG 144
Query: 74 ITEGLYLLGILALR-GRKVIIPRHTYGEYERVARIFNAKIIKGSNEP------EKLAELV 126
E + L+ L G ++ T+ YE A + A +IK P E++AE+V
Sbjct: 145 ADELIDLIMRCVLDPGDMIVDCPPTFTMYEFDAAVNGAHVIKVPRNPDFSLDVERIAEVV 204
Query: 127 ENNS--VVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFV----KDAKSP 180
E+ +F +PNNPDG L ++D L++LDEA+++F K
Sbjct: 205 EHEKPKCIFLTSPNNPDGSIVDDETLLKILDL----PILVILDEAYVEFSGMESKMKWVK 260
Query: 181 EGENIVKLRTFTKSYGLPGIRVGY------IIGFRDAFRSVRMPWSIGSTGVAFLEFLIE 234
+ EN++ LRTF+K GL G+RVGY II F + P+++ S
Sbjct: 261 KHENLIVLRTFSKRAGLAGLRVGYGAFPKSIIEF---LWRAKQPYNV-SVAAEVAACAAL 316
Query: 235 DNFEHLRKTMPLIWQEKERIEKALN-------VKSDANFFIKYVG---DAKKAVEELKKR 284
N +L + QE+ER+ L S +NF + V DAKK E+L
Sbjct: 317 KNPTYLENVKVALVQERERLFNLLKEVPFLDPYPSYSNFILCKVTSGMDAKKLKEDLATM 376
Query: 285 GILVRDCTSFGLPGYIRFSVRRAEENERLVQALK 318
G+++R S L GY+R SV + E E L++ LK
Sbjct: 377 GVMIRHYNSKELKGYVRVSVGKPEHTEALMKCLK 410
>dbj|BAB05308.1| (AP001512) aminotransferase (cobalamin biosynthesis) [Bacillus
halodurans]
Length = 370
Score = 100 bits (247), Expect = 2e-20
Identities = 87/352 (24%), Positives = 163/352 (45%), Gaps = 42/352 (11%)
Query: 4 PVRFSTHHGGARRNEIKLIDFSASVNPY--PPEWVDEMFKRAREISFS-YPYYEELEDEL 60
P +T G + E IDFS + NP+ PP+ + + K+ + F+ YP E E
Sbjct: 10 PKTLATQMGTSLTGEA--IDFSVNTNPFGPPPQLLAYLRKQLDQGLFTQYPDQEASELAR 67
Query: 61 SELLNEEIT-----ITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKG 115
+ + E + + G + +Y + L + R I+ T+ EYE + + +
Sbjct: 68 AIAIKEHVPPSSVLVANGAAQIIYTIAQLWHKQRVAIV-EPTFSEYEEACLANDCSVERI 126
Query: 116 SNEP------EKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEA 169
P +++ +++ ++F C+PNNP G Y +L L++ + LV+DEA
Sbjct: 127 MLPPPWSLDLDRMTAVLKRTDLLFICHPNNPTGVAYRKEQLIELLELAKQFGTTLVIDEA 186
Query: 170 FIDFVK-----DAKSPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSVRM---PWSI 221
F DF++ A++ E I+ +R+ TK + +PG+R+GY I ++ PWS+
Sbjct: 187 FYDFMEVPITFTAQAAANEGIIVVRSMTKMFTIPGLRLGYAISAPSVIEKLKSKIPPWSV 246
Query: 222 GSTGVAFLEFLIEDNFEHLRKTMPLIWQEKERIEKALN------VKSDANFFIKYVGDAK 275
+F + + +R + I + ++ S NFF+ + D +
Sbjct: 247 NGLADKAGQFCLRETM-FVRDSAQRIAAARAEMQAGFRHLGFDVSPSVVNFFV--ISDPR 303
Query: 276 KAV------EELKKRGILVRDCTSF-GLPG-YIRFSVRRAEENERLVQALKD 319
+++ + L RG ++R +F GL G Y+R +V+ + N +L+QA+KD
Sbjct: 304 ESIGMLAMLKGLLDRGFVLRHTENFPGLDGRYLRVAVKDQDTNRKLLQAVKD 355
>pir||F83250 histidinol-phosphate aminotransferase PA3165 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9949281|gb|AAG06553.1|AE004740_6 (AE004740)
histidinol-phosphate aminotransferase [Pseudomonas
aeruginosa]
Length = 369
Score = 99.8 bits (245), Expect = 4e-20
Identities = 75/275 (27%), Positives = 133/275 (48%), Gaps = 26/275 (9%)
Query: 67 EITITAGITEGLYLLGILALR-GRKVIIPRHTYGEYERVARIFNA--KIIK----GSNEP 119
++T+ G + L L+ L G + H + Y + A + +K G +
Sbjct: 90 QVTLGNGSNDILDLVARAYLAPGLNAVFSEHAFAVYPIATQAVGAEGRAVKARAWGHDLE 149
Query: 120 EKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKS 179
LA + VVF NPNNP G ++ L+ + V + L+VLDEA+I++ + +
Sbjct: 150 AMLAAIDGQTRVVFVANPNNPTGTWFGADALERFLAQVP-AEVLVVLDEAYIEYAEGDEL 208
Query: 180 PEG-------ENIVKLRTFTKSYGLPGIRVGYIIGFR---DAFRSVRMPWSIGSTGVAFL 229
P+G N++ RTF+K+YGL +RVGY + + D VR P+++ S +A
Sbjct: 209 PDGLDYLARHPNLLVSRTFSKAYGLASLRVGYALSSKAVADVLNRVRQPFNVNSLALAAA 268
Query: 230 EFLIEDNFEHLRKTMPLIWQEKERIEKALN------VKSDANFF-IKYVGDAKKAVEELK 282
++D+ ++L ++ L ++E + + S NF + DA + L
Sbjct: 269 CAALDDH-DYLAQSRRLNDSGMAQLEDGFHALGLSWIPSKGNFIAVDLARDAGPVYQALL 327
Query: 283 KRGILVRDCTSFGLPGYIRFSVRRAEENERLVQAL 317
+ G++VR +G+P ++R S+ EEN+R +QAL
Sbjct: 328 REGVIVRPVAGYGMPTFLRVSIGLPEENDRFLQAL 362
>pir||G72304 histidinol-phosphate aminotransferase - Thermotoga maritima
(strain MSB8) >gi|4981581|gb|AAD36117.1|AE001764_20
(AE001764) histidinol-phosphate aminotransferase
[Thermotoga maritima]
Length = 335
Score = 97.9 bits (240), Expect = 1e-19
Identities = 81/315 (25%), Positives = 153/315 (47%), Gaps = 40/315 (12%)
Query: 30 PYPPEWVDEMFKRAREISFSYPYYEELEDELSE----------LLNEEITITAGITEGLY 79
P+P + VDE+F+R + YY+ ++EL E L +++ G E +Y
Sbjct: 32 PFPEDLVDEVFRRLNSDALRI-YYDSPDEELIEKILSYLDTDFLSKNNVSVGNGADEIIY 90
Query: 80 LLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPE-KLAEL-VENNSVVFFCNP 137
++ + + R V P TY Y A+ AK ++ + ++ E+ V VVF NP
Sbjct: 91 VM--MLMFDRSVFFPP-TYSCYRIFAKAVGAKFLEVPLTKDLRIPEVNVGEGDVVFIPNP 147
Query: 138 NNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSP---EGENIVKLRTFTKS 194
NNP G + E++ ++ A + LDEA+ +F ++ + EN+ +RTF+K+
Sbjct: 148 NNPTGHVFEREEIERILKT----GAFVALDEAYYEFHGESYVDFLKKYENLAVIRTFSKA 203
Query: 195 YGLPGIRVGYIIG---FRDAFRSVRMPWSIGSTGVAFLEFLIEDNFEHLRKTMPLIWQEK 251
+ L RVGY++ F DA+ VR+P+++ F + + D+ E + I +E+
Sbjct: 204 FSLAAQRVGYVVASEKFIDAYNRVRLPFNVSYVSQMFAKVAL-DHREIFEERTKFIVEER 262
Query: 252 ERIEKALN------VKSDANFFIKYV--GDAKKAVEELKKRGILVRDCTSFGLPGYIRFS 303
ER++ AL S NF ++ + ++ +E L+ + + VR +R +
Sbjct: 263 ERMKSALREMGYRITDSRGNFVFVFMEKEEKERLLEHLRTKNVAVRSFRE-----GVRIT 317
Query: 304 VRRAEENERLVQALK 318
+ + EEN+ +++ L+
Sbjct: 318 IGKREENDMILRELE 332
>sp|O27624|HIS8_METTH PROBABLE HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE
ACETOL-PHOSPHATE TRANSAMINASE) >gi|7450422|pir||G69078
histidinol-phosphate aminotransferase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622710|gb|AAB86060.1| (AE000918)
histidinol-phosphate aminotransferase [Methanobacterium
thermoautotrophicum]
Length = 373
Score = 97.5 bits (239), Expect = 2e-19
Identities = 93/338 (27%), Positives = 159/338 (46%), Gaps = 39/338 (11%)
Query: 18 EIKLIDFSASVNPYPPEWVD-EMFKRAREISFSYP------YYEELEDELSELLNEEITI 70
E ++I ++ NP P E +R E YP E + D +++ I
Sbjct: 38 EDEIIKLGSNENPLGPSPAAVEAMERELESVHRYPESALTDLREAIADYAGVGMDQVIVG 97
Query: 71 TAGITEGLYLLGILALR-GRKVIIPRHTYGEYERVARIFNAKIIKGS---NEPEKLAELV 126
G E + +LG L G ++P +Y YE + +A+ + NE E V
Sbjct: 98 GDGADEIIDVLGRTFLEPGESFVVPMPSYMYYEYTLQAHDARAVHARWDVNENRLDLESV 157
Query: 127 -----ENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKS-- 179
E+ +VF C PNNP G ++++ ++++ + L+V+DEA+ +F +
Sbjct: 158 LDAVDESTRLVFLCTPNNPTGGLIDKKDIRAVLESTD---TLVVVDEAYTEFAGVDNTDL 214
Query: 180 -PEGENIVKLRTFTKSYGLPGIRVGYIIG----------FRDAFRSVRMPWSIGSTGVAF 228
P+ EN+ LRTF+K GL G+R+GY +G + F R+ + +
Sbjct: 215 LPDHENLFILRTFSKVMGLAGMRIGYGLGDPQIIEYMHRVKPVFSLTRLSHAAALATIRD 274
Query: 229 LEFLIEDNFEHLRKTMPLIWQEKERIEKALNVKSDANFFIKYV-GDAKKAV---EELKKR 284
++ I+ + E+ K+ ++ ++ + +S AN+ + V G + A EEL ++
Sbjct: 275 RDY-IKKSTEYSIKSREYLYSGLKKFPELRVFRSYANYILIDVRGTGRTAAELSEELLRK 333
Query: 285 GILVRDCTSF-GLPGY-IRFSVRRAEENERLVQALKDL 320
GI+VRDCTSF GL Y IR SV EE+ R ++ L +L
Sbjct: 334 GIIVRDCTSFTGLDEYWIRVSVGTLEEDRRFLEVLGEL 371
>pir||T36050 probable histidinol-phophate aminotransferase - Streptomyces
coelicolor >gi|3928720|emb|CAA22216.1| (AL034355)
putative histidinol-phophate aminotransferase
[Streptomyces coelicolor A3(2)]
Length = 359
Score = 96.3 bits (236), Expect = 4e-19
Identities = 91/333 (27%), Positives = 147/333 (43%), Gaps = 41/333 (12%)
Query: 25 SASVNPYPP-EWVDEMFKRAREISFSYP------YYEELEDELSELLNEEITITAGITEG 77
S++ NPYPP V E A YP EL D L T T +
Sbjct: 35 SSNENPYPPLPGVMETVTAAAASFNRYPDMACTSLMAELSDRFGVPLAHLATGTGSVGVA 94
Query: 78 LYLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPEKLAEL-------VENNS 130
L+ + G +VI ++ Y + +I A+ ++ P ++ +L +
Sbjct: 95 QQLIQATSGPGDEVIYAWRSFEAYPIITQISGARSVQVPLTPGEVHDLDAMADAITDRTR 154
Query: 131 VVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPEG-------E 183
++F CNPNNP G EL+ +D V L+VLDEA+ +F++DA+ P+G
Sbjct: 155 LIFVCNPNNPTGTVVRRAELERFLDRVPS-DVLVVLDEAYREFIRDAEVPDGVEFYRERP 213
Query: 184 NIVKLRTFTKSYGLPGIRVGYIIGFRD---AFRSVRMPWSIGSTG--VAFLEFLIEDNFE 238
N+ LRTF+K+YGL G+RVG+ I A R +P+ + A ED E
Sbjct: 214 NVCVLRTFSKAYGLAGLRVGFAIAHEPVAAALRKTAVPFGVSQIAQEAAIASLRAED--E 271
Query: 239 HLRKTMPLIWQEKERIEKALNV------KSDANFFIKYVGDAKKA-VEELKKRGILVRDC 291
+ + L+ E+ R+ AL +S ANF +G+ A ++ G++VR
Sbjct: 272 LIGRVGSLVC-ERARVADALRAQGWTVPESQANFVWLRLGERTLAFANACEQAGVVVRPF 330
Query: 292 TSFGLPGYIRFSVRRAEENERLVQALKDLSPEL 324
G +R +V +E N+ ++ ++ EL
Sbjct: 331 AGEG----VRVTVGESEANDIFLKVSEEFRKEL 359
>gb|AAC79515.1| (U90625) CobD [Salmonella typhimurium]
Length = 364
Score = 96.0 bits (235), Expect = 6e-19
Identities = 96/360 (26%), Positives = 158/360 (43%), Gaps = 53/360 (14%)
Query: 7 FSTHHGGARRNEIK--------LIDFSASVNPY------PPEWVDEMFKRAREISFSYPY 52
F+T HGG R L+DF+A++NP P +D + R Y +
Sbjct: 4 FNTAHGGNIREPATVLGISPDHLLDFTANINPLGMPVSLKPPLIDNLDCIERYPDADYFH 63
Query: 53 YEELEDELSELLNEEITITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKI 112
+ ++ I G TE ++ + L+ R+ +I + EY R +I
Sbjct: 64 LHQALARHHQVPASWILAGNGETESIFTVAS-GLKPRRAMIVTPGFAEYGRALAQSGCEI 122
Query: 113 IKGSNEPEK--------LAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDR-KAL 163
+ S L L + +F C PNNP G P +PL+ A+ DR K+L
Sbjct: 123 RRWSLREADGWQLTDAILEALTPDLDCLFLCTPNNPTG--LLPE--RPLLQAIADRCKSL 178
Query: 164 ---LVLDEAFIDFVKDAKS-----PEGENIVKLRTFTKSYGLPGIRVGYIIGFRDA---- 211
L+LDEAFIDF+ + +I LR+ TK Y +PG+R+GY++ DA
Sbjct: 179 NINLILDEAFIDFIPHETGFIPALKDNPHIWVLRSLTKFYAIPGLRLGYLVNSDDAAMAR 238
Query: 212 FRSVRMPWSIGSTGVAFLEFLIEDN------FEHLRKTMPLIWQEKERIEKALNVKSDAN 265
R +MPWS+ + E ++D+ + LR+ +Q ++ AN
Sbjct: 239 MRRQQMPWSVNALAALAGEVALQDSAWQQATWHWLREEGARFYQALCQLPLLTVYPGRAN 298
Query: 266 F-FIKYVGDAKKAVEELKKRGILVRDCTSFGLPG----YIRFSVRRAEENERLVQALKDL 320
+ ++ + L + IL+R C ++ PG Y R ++R A +NERL+ AL+++
Sbjct: 299 YLLLRCEREDIDLQRRLLTQRILIRSCANY--PGLDSRYYRVAIRSAAQNERLLAALRNV 356
>sp|O07131|HIS8_METFL HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|2149217|gb|AAB58526.1| (U83322)
imidazoleacetol phosphate aminotransferase
[Methylobacillus flagellatus]
Length = 368
Score = 95.6 bits (234), Expect = 7e-19
Identities = 67/254 (26%), Positives = 126/254 (49%), Gaps = 23/254 (9%)
Query: 88 GRKVIIPRHTYGEYERVARIFNAKIIKG-----SNEPEKLAELVENNSVVFFCNPNNPDG 142
G + + +H + Y V + A I ++ + + + + + +F NPNNP G
Sbjct: 112 GTEAVYAQHAFAVYALVTQATGASGISVPARDFGHDLDAMLAAITDKTRLFIANPNNPTG 171
Query: 143 RYYTPRELKPLIDAVEDRKALLVLDEAFIDFVK-DAKSP------EGENIVKLRTFTKSY 195
+ L+ + V R+ L+VLDEA+ +++ + KS E +N++ RT +K+Y
Sbjct: 172 TLLSKPALRDFLAKVP-RQVLVVLDEAYDEYLAAELKSEAFSWLAEFDNLLISRTLSKAY 230
Query: 196 GLPGIRVGYII---GFRDAFRSVRMPWSIGSTGVAFLEFLIEDNFEHLRKTMPLIWQEKE 252
GL G+RVG+ + G D VR P+++ S A +ED+ E + ++ L +
Sbjct: 231 GLAGLRVGFGVTSPGVADLMNRVRQPFNVNSVAQAAAVAALEDD-EFVERSYALNQAGMQ 289
Query: 253 RIEKALN------VKSDANFFIKYVGDAKKAVEELKKRGILVRDCTSFGLPGYIRFSVRR 306
++ + L + S NF +V A + ++L KRG++VR ++ +P Y+R S+
Sbjct: 290 QLTEGLARLGLSYIPSYGNFVSFHVAQAAEVYQQLLKRGVIVRPVAAYDMPDYLRVSIGL 349
Query: 307 AEENERLVQALKDL 320
EN R ++ L+ +
Sbjct: 350 HAENARFLEVLEQI 363
>gi|10957440 histidinol-phosphate aminotransferase [Deinococcus radiodurans]
>gi|7472014|pir||C75619 histidinol-phosphate
aminotransferase - Deinococcus radiodurans (strain R1)
>gi|6460869|gb|AAF12573.1|AE001826_42 (AE001826)
histidinol-phosphate aminotransferase [Deinococcus
radiodurans]
Length = 335
Score = 93.6 bits (229), Expect = 3e-18
Identities = 87/325 (26%), Positives = 144/325 (43%), Gaps = 22/325 (6%)
Query: 11 HGGARRNEIKLIDFSASVNPYPPE-WVDEMFKRAREISFSYPYYEELEDELSE---LLNE 66
HGG +DFS + NPY P + + A + P Y + L++ + +
Sbjct: 15 HGGPSSAAFVGLDFSVNCNPYGPNPALLAAVRGADHAHYPDPSYLGVRRRLADWHGVSPD 74
Query: 67 EITITAGITEGLYLLGILALRGRKVIIPRHT-YGEYERVARIFNAKIIKGSNEPEKLAEL 125
E+ ++ G ++ L+ + L V++ H +GE R A++ AKI P A L
Sbjct: 75 EVVLSVGASDLLHRVVRAFLPAGDVLLSLHAPFGELARAAQLQRAKIHVMDEVP---AAL 131
Query: 126 VENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPEGENI 185
+V+ P+NP GR EL L +A ALLVLD A+ F+ P +
Sbjct: 132 PPRTRLVYVGQPHNPTGRRLCAPELDILANACAAAHALLVLDLAYAPFLS---LPVHHHP 188
Query: 186 VKLRTFT--KSYGLPGIRVGYIIGFRDA---FRSVRMPWSIGSTGVAFLEFLIEDNFEHL 240
+ + K++GL G R Y + + ++ W + + G A L + + L
Sbjct: 189 FTINVLSPGKAHGLVGARPAYALARAEVTARLDNLAPAWHLPA-GTAALLAALPAAQDFL 247
Query: 241 RKTMPLIWQEKERIEKALNV-----KSDANFFIKYVGDAKKAVEELKKRGILVRDCTSFG 295
+T+P + + + AL + F VGDA +L GI VRDC S+G
Sbjct: 248 SETLPRVQNDAAALAHALREFGPVERRGTPFLTLEVGDAAAVARKLLPLGIRVRDCASYG 307
Query: 296 LPGYIRFSVRRAEENERLVQALKDL 320
LPG +R S + + + RL+ AL+++
Sbjct: 308 LPGRVRVSTQANKNDRRLIGALQEV 332
>sp|Q57004|YB66_HAEIN PROBABLE AMINOTRANSFERASE HI1166 >gi|1074205|pir||D64187
histidinol-phosphate transaminase homolog - Haemophilus
influenzae (strain Rd KW20) >gi|1574093|gb|AAC22821.1|
(U32796) histidinol-phosphate aminotransferase (hisH)
[Haemophilus influenzae Rd]
Length = 366
Score = 93.2 bits (228), Expect = 4e-18
Identities = 70/280 (25%), Positives = 132/280 (47%), Gaps = 36/280 (12%)
Query: 67 EITITAGITEGLYLLG-ILALRGRKVIIPRHTYGEYERVARIFNAKIIK-------GSNE 118
+IT+ G + L L A G +++ ++ + Y V + NA I+K G +
Sbjct: 87 QITLGNGSNDLLELFAHTFATEGDEIMYSQYAFIVYPLVTKAINA-IVKEIPAKNWGHDL 145
Query: 119 PEKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAK 178
L L + +++ NPNNP G + T +E++ + V + ++VLDEA+ +F + +
Sbjct: 146 QGFLTALSDKTKLIYIANPNNPTGNFLTSQEIEDFLAEVPEN-VIVVLDEAYTEFTRSEE 204
Query: 179 SPEG-------ENIVKLRTFTKSYGLPGIRVGYIIG---FRDAFRSVRMPWSIGSTGVA- 227
+ N++ R+ +K+YGL G+R+GY + D VR P++ S +
Sbjct: 205 RVDSFSLLKKYSNLIISRSLSKAYGLAGLRIGYAVSNPEIADLLNRVRQPFNCNSLALTA 264
Query: 228 ---------FLEFLIEDNFEHLRKTMPLIWQEKERIEKALNVKSDANFF-IKYVGDAKKA 277
F+E + E+N +R+ +K +++ + S NF I + A
Sbjct: 265 AVAVMNDDKFVEKVAENNRIEMRRYEDFC--QKNQLDY---IPSKGNFITIDFKQPAAPI 319
Query: 278 VEELKKRGILVRDCTSFGLPGYIRFSVRRAEENERLVQAL 317
+ L + G++VR +G+P ++R S+ EEN++ AL
Sbjct: 320 YDALLREGVIVRPIAGYGMPNHLRISIGLPEENDKFFTAL 359
>sp|P17731|HIS8_BACSU HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|98328|pir||A26532 histidinol-phosphate
transaminase (EC 2.6.1.9) / tyrosine and phenylalanine
aminotransferase hisC - Bacillus subtilis
>gi|143814|gb|AAA20867.1| (M80245) HisH [Bacillus
subtilis] >gi|2634680|emb|CAB14178.1| (Z99115)
histidinol-phosphate aminotransferase [Bacillus
subtilis]
Length = 360
Score = 90.5 bits (221), Expect = 2e-17
Identities = 88/336 (26%), Positives = 151/336 (44%), Gaps = 41/336 (12%)
Query: 20 KLIDFSASVNPYP-PEWVDEMFKRAREISFSYP--YYEELEDELSELLNEEITITA---G 73
K++ +++ NPY E E + YP Y L LS+ LN T G
Sbjct: 30 KVVKLASNENPYGCSEAAKEALHHEIQQLALYPDGYSAALRTRLSKHLNVSETSLIFGNG 89
Query: 74 ITEGLYLLGILALRGR-KVIIPRHTYGEYERVARIFNAKIIK------GSNEPEKLAELV 126
E + ++ L + + T+ +Y+ A I A++ + GS++ + + E +
Sbjct: 90 SDEIIQIICRAFLNDKTNTVTAAPTFPQYKHNAVIEGAEVREIALRPDGSHDLDAMLEAI 149
Query: 127 -ENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPEG--- 182
E VV+ C+PNNP G Y + EL ++ V R L+VLDEA+ ++V PE
Sbjct: 150 DEQTQVVWICSPNNPTGTYTSEGELLAFLERVPSR-VLVVLDEAYYEYVTAEDYPETVPL 208
Query: 183 ----ENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSV---RMPWSIGSTG---------- 225
N++ LRTF+K+YGL +RVGY I + R + R P++ G
Sbjct: 209 LSKYSNLMILRTFSKAYGLAALRVGYGIADENLIRQIEPAREPFNTSRLGQAAAIAALYD 268
Query: 226 VAFLEFLIEDNFEHLRKTMPLIWQEKERIEKALNVKSDANF-FIKYVGDAKKAVEELKKR 284
AF+ +E N L++ + + + S NF I + A + + L ++
Sbjct: 269 QAFIASCVEQNNAGLQQ-----YYDFAKTHGLKCYPSQTNFVLIDFKRPADELFQALLEK 323
Query: 285 GILVRDCTSFGLPGYIRFSVRRAEENERLVQALKDL 320
G +VR + G P +R ++ E+NE ++ L ++
Sbjct: 324 GYIVRSGNALGFPTSLRITIGTKEQNEEILAILAEI 359
>pir||E70478 histidinol-phosphate aminotransferase - Aquifex aeolicus
>gi|2984289|gb|AAC07813.1| (AE000771)
histidinol-phosphate aminotransferase [Aquifex aeolicus]
Length = 354
Score = 90.1 bits (220), Expect = 3e-17
Identities = 92/342 (26%), Positives = 157/342 (45%), Gaps = 43/342 (12%)
Query: 14 ARRNEIKLIDFSASVNPYPPEWVDEMFKRAREISFSYPYYEELEDELSELL--------- 64
A + E+ S N +P ++ +E+ +RA E P + + E EL
Sbjct: 11 AYKTEVTPASVRLSSNEFPYDFPEEIKQRALEELKKVPLNKYPDPEAKELKAVLADFFGV 70
Query: 65 -NEEITITAGITEGLYLLGI-LALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEP--- 119
E + + G E +Y L I + V IP T+ YE A++ ++K +
Sbjct: 71 KEENLVLGNGSDELIYYLSIAIGELYIPVYIPVPTFPMYEISAKVLGRPLVKVQLDENFD 130
Query: 120 ---EKLAELVENNSVV--FFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFI--- 171
E+ EL+E V +F PNNP G ++ + I+ + +R V+DEA+
Sbjct: 131 IDLERSIELIEKEKPVLGYFAYPNNPTGNLFS----RGKIEEIRNRGVFCVIDEAYYHYS 186
Query: 172 --DFVKDAKSPEGENIVKLRTFTKSYGLPGIRVGYIIG---FRDAFRSVRMPWSIGSTGV 226
F++DA + E+ V LRT +K G+ +RVG +IG VR+P+++
Sbjct: 187 GETFLEDAL--KREDTVVLRTLSK-IGMASLRVGILIGKGEIVSEINKVRLPFNVTYPSQ 243
Query: 227 AFLEFLIEDNFEHLRKTMPLIWQEKER-------IEKALNVKSDANFFI-KYVGDAKKAV 278
+ L+ + E L + + + +E+ER IE S ANF + + A +
Sbjct: 244 VMAKVLLTEGREFLMEKIQEVVKERERMYDEMKKIEGVEVFPSKANFLLFRTPYPAHEVY 303
Query: 279 EELKKRGILVRDCTSF-GLPGYIRFSVRRAEENERLVQALKD 319
+EL KR +LVR+ + GL +R SV + EEN + ++AL++
Sbjct: 304 QELLKRDVLVRNVSYMEGLQKCLRVSVGKPEENNKFLEALEE 345
>dbj|BAB05384.1| (AP001512) histidinol-phosphate aminotransferase/tyrosine and
phenylalanine aminotransferase [Bacillus halodurans]
Length = 369
Score = 90.1 bits (220), Expect = 3e-17
Identities = 83/343 (24%), Positives = 160/343 (46%), Gaps = 40/343 (11%)
Query: 21 LIDFSASVNPYPPE-WVDEMFKRAREISFSYP--YYEELEDELSELLN---EEITITAGI 74
++ +++ NP+ V E + A + YP Y L D+++ + EE+ G
Sbjct: 31 VVKLASNENPFGASPKVAEAIQEALHHTAIYPDGYARTLRDKVAHYVGVAPEELIFGNGS 90
Query: 75 TEGLYLLGILALRGR-KVIIPRHTYGEYERVARIFNAKIIK-----GSNEPEKLAELV-E 127
E + +L L + ++ T+ +Y+ A I A++ + G ++ + + E++ E
Sbjct: 91 DEVIQILCRAFLNEQTNTVMAEPTFSQYKLNAVIEGAELREVPLKDGVHDLDGMLEVIDE 150
Query: 128 NNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPEG----- 182
N +V+ CNPNNP G Y + + + V + L+V DEA++++V P+
Sbjct: 151 NTRIVWVCNPNNPTGTYVSAEAFQSFLAKVPE-DVLVVSDEAYVEYVTADDYPDTVPMIR 209
Query: 183 --ENIVKLRTFTKSYGLPGIRVGYIIGFR---DAFRSVRMPWSIGSTGV----------A 227
+N+V LRTF+K +GL +R+GY + + + VR P++ + A
Sbjct: 210 TYKNLVVLRTFSKVFGLAALRIGYGVANQALIEKIEPVRPPFNNSTFSQVAAVAALEDEA 269
Query: 228 FLEFLIEDNFEHLRKTMPLIWQEKERIEKALNVKSDANFFIKYVGDAKKAV-EELKKRGI 286
F++ +E N E + + W + ++ S NF + +V + V + K+G
Sbjct: 270 FVQSSVEKNNEGMEQLTE--WCSRMGLDY---FPSQTNFLLIHVNRSSDDVFNAMLKKGY 324
Query: 287 LVRDCTSFGLPGYIRFSVRRAEENERLVQALKDLSPELLAPVH 329
++R + G P +IR ++ E+N+ + AL D+ E L H
Sbjct: 325 IIRSGRALGYPAWIRITIGSKEQNDGCLAALADVLAEELTTQH 367
>pir||T45247 probable histidinol-phosphate transaminase (EC 2.6.1.9) [imported]
- Mycobacterium leprae >gi|4883453|emb|CAB43167.1|
(AL049913) putative histidinol-phosphate
aminotransferase [Mycobacterium leprae]
Length = 377
Score = 89.7 bits (219), Expect = 4e-17
Identities = 90/342 (26%), Positives = 150/342 (43%), Gaps = 53/342 (15%)
Query: 29 NPYPPE--WVDEMFKRAREISFSYPYYEE-----LEDELSELLNEEITITAGITE----- 76
NP+PP VD++ + ++++ Y + L +L+ L + I G+
Sbjct: 39 NPHPPTKALVDDVVRSVQKVAVDLHRYPDRDAVALRQDLASYLTAQTGIRLGVENIWAAN 98
Query: 77 ----------------GLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPE 120
G +G + II T+ E+ R + + E
Sbjct: 99 GSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIIADGTHTEWLETVRADDFSL---DVEAA 155
Query: 121 KLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVK--DAK 178
A VVF +PNNP G+ + +L+ L+D V +L++DEA+ +F A
Sbjct: 156 VTAVADRKPDVVFIASPNNPSGQSISLADLRRLLDVVP---GILIVDEAYGEFSSRPSAV 212
Query: 179 SPEGE---NIVKLRTFTKSYGLPGIRVGYIIG---FRDAFRSVRMPWSIGSTGVAFLEFL 232
+ GE IV RT +K++ G R+GY+I +A VR+P+ + S A
Sbjct: 213 ALVGEYPTKIVVTRTTSKAFAFAGGRLGYLIATPALVEAMLLVRLPYHLSSVTQAAARAA 272
Query: 233 IEDNFEHLRKTMPLIWQEKERIEKALN------VKSDANFFI-KYVGDAKKAVEELKKRG 285
+ + L LI E+ER+ K+L + SDANF + + DA A + G
Sbjct: 273 LRHADDTLGSVAALI-AERERVTKSLVHMGFRVIPSDANFVLFGHFSDAAGAWQHYLDTG 331
Query: 286 ILVRDCTSFGLPGYIRFSVRRAEENERLVQALKDLSPELLAP 327
+L+RD G+PGY+R + AEEN+ ++A +++ LAP
Sbjct: 332 VLIRDV---GIPGYLRATTGLAEENDAFLKASSEIAATELAP 370
>pir||H70694 probable histidinol-phosphate aminotransferase - Mycobacterium
tuberculosis (strain H37RV) >gi|1552855|emb|CAB02479.1|
(Z80343) hisC2 [Mycobacterium tuberculosis]
Length = 353
Score = 89.7 bits (219), Expect = 4e-17
Identities = 65/211 (30%), Positives = 106/211 (49%), Gaps = 23/211 (10%)
Query: 122 LAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPE 181
LA + + ++F CNPNNP P L ++AV L+ +DEA++++++D P+
Sbjct: 140 LATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAH-ILIAIDEAYVEYIRDGMRPD 198
Query: 182 G-------ENIVKLRTFTKSYGLPGIRVGYIIGFRD---AFRSVRMPWSIGSTGVAFLEF 231
N+V LRTF+K+YGL G+R+GY IG D A V +P+++ S G A
Sbjct: 199 SLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIA 258
Query: 232 LIEDNFEHLRKTMPLIWQEKERIEKALNV------KSDANFFIKYVGD-AKKAVEELKKR 284
++ E L +T ++ E+ R+ L S ANF +G + VE+
Sbjct: 259 SLDAADELLARTDTVV-AERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADA 317
Query: 285 GILVRDCTSFGLPGYIRFSVRRAEENERLVQ 315
I+VR +G G +R +V EEN+ ++
Sbjct: 318 RIVVR---PYGTDG-VRVTVAAPEENDAFLR 344
>gb|AAD47361.1|AF038578_4 (AF038578) imidazole acetol phosphate aminotransferase [Pseudomonas
stutzeri]
Length = 366
Score = 88.5 bits (216), Expect = 9e-17
Identities = 73/276 (26%), Positives = 124/276 (44%), Gaps = 21/276 (7%)
Query: 63 LLNEEITITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAK------IIKGS 116
L +E+IT+ G + + L+ G + H + Y + A+ + G
Sbjct: 87 LKSEQITLGNGSNDIIDLVARCCGAGPNAVFSAHAFAAYPLCTQAAGAESRVVPAVDYGH 146
Query: 117 NEPEKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKD 176
+ L + E +V+F NPNNP G + L+ +D V +R L+VLDEA+I+F +
Sbjct: 147 DLDGMLKAIDEQTAVIFIANPNNPTGNLVRAQALESFLDRVPER-VLVVLDEAYIEFYRG 205
Query: 177 AKSP------EGENIVKLRTFTKSYGLPGIRVGYIIG---FRDAFRSVRMPWSIGSTGV- 226
N++ RT +K YGL G+RVGY D VR P+++ S +
Sbjct: 206 TNCQRLNYLVRYPNLLVSRTLSKVYGLAGLRVGYSASSPQIADVLNRVRQPFNVNSLALV 265
Query: 227 -AFLEFLIEDNFEHLRKTMPLIWQ-EKERIEKALN-VKSDANFFIKYVG-DAKKAVEELK 282
A ++ + + +W+ E+ E L + S NF +G DA L
Sbjct: 266 AACAGWMTSSIWLKGGGWIAPVWELEQGLAELRLKWIPSRGNFLAVDLGRDAAPINAGLL 325
Query: 283 KRGILVRDCTSFGLPGYIRFSVRRAEENERLVQALK 318
+ G++VR + P ++R S+ +EN R ++AL+
Sbjct: 326 RDGVIVRPIAGYDCPTFLRVSIGTEQENARFLEALR 361
>pir||A81451 probable histidinol-phosphate transaminase (EC 2.6.1.9) Cj0317
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6967791|emb|CAB72784.1| (AL139074) probable
histidinol-phosphate aminotransferase [Campylobacter
jejuni]
Length = 364
Score = 87.0 bits (212), Expect = 3e-16
Identities = 92/329 (27%), Positives = 156/329 (46%), Gaps = 40/329 (12%)
Query: 20 KLIDFSASVNPY--PPEWVDEMFKRAREISFSYPYYE--ELEDELSE---LLNEEITITA 72
++I +++ NP+ PP+ ++ + + A + YP EL+ L++ + NE I I A
Sbjct: 30 EVIKLASNENPFGTPPKAIECLRQNANKAHL-YPDDSMIELKSTLAQKYKVQNENIIIGA 88
Query: 73 GITEGLYLLGILALRGRKVIIPRH-TYGEYERVARIFNAKIIKGSNEPEKLAE---LVEN 128
G + + L + + T+ YE A+ AK K + L E L E
Sbjct: 89 GSDQVIEFAIHSKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHNLDEFKKLYET 148
Query: 129 NS----VVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFV--KDAKS--- 179
+ ++F C PNNP G E I V + L+V+D A+ +F KD+K
Sbjct: 149 HKDEIKLIFLCLPNNPLGECLDASEATEFIKGVNE-DCLVVIDAAYNEFASFKDSKKHLE 207
Query: 180 -----PEGENIVKLRTFTKSYGLPGIRVGYII---GFRDAFRSVRMPWSIGSTGVAFLEF 231
E +N++ L TF+K YGL G+R+GY I AF +R P+++ + +
Sbjct: 208 PCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIANANIISAFYKLRAPFNVSNLALKAAVA 267
Query: 232 LIEDNFEHLRKTMPLIWQEKE---RIEKALNVKSDANF--FIKYVGDAKKAV---EELKK 283
++D+ E KT+ + + E K N+K ++ FI Y D K + E+L K
Sbjct: 268 AMDDD-EFTEKTLENNFSQMELYKEFAKKHNIKIIDSYTNFITYFFDEKNSTDLSEKLLK 326
Query: 284 RGILVRDCTSFGLPGYIRFSVRRAEENER 312
+GI++R+ S+GL IR ++ + ENE+
Sbjct: 327 KGIIIRNLKSYGL-NAIRITIGTSYENEK 354
>emb|CAB62740.1| (AL133423) putative aminotransferase [Streptomyces coelicolor
A3(2)]
Length = 541
Score = 86.6 bits (211), Expect = 4e-16
Identities = 93/340 (27%), Positives = 152/340 (44%), Gaps = 46/340 (13%)
Query: 22 IDFSASVNPY--PPEWVDEMFKRAREISFSYPYYEE-LEDELSELLN---EEITITAGIT 75
+DF NPY P DE+ R R+I YP + + EL LL + + + G T
Sbjct: 35 VDFCIPCNPYFPTPAMFDELAGRLRDIVTYYPSSADTITAELCSLLQLPPQCVAMGNGST 94
Query: 76 EGLYLLGILALRGRKVIIPRHTYGEY-----ERVARIFNAKIIKGSNEPEKLAELVE--- 127
E + + L +R + +P T+G + E R+ + + LA E
Sbjct: 95 ELITWIDHLLVR-ESLAVPVPTFGRWTDQPMETGKRVDMFPLQEAGGFALDLARYGEFVR 153
Query: 128 --NNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPE---- 181
V CNPNNPDG Y + L +DA+ DR L+V+DE+F++F P
Sbjct: 154 ARGTRAVVVCNPNNPDGGYLHKQALVQFMDAMADRD-LVVIDESFLEFADAEAEPSVVQE 212
Query: 182 ---GENIVKLRTFTKSYGLPGIRVGYII---GFRDAFRSVRMPWSIGSTGVAFLEFLIED 235
N+V LR+ K++GL GIR GY++ R++ W++ S + F++ D
Sbjct: 213 AMLRPNVVVLRSLGKNFGLHGIRFGYLVANPALAGRVRAMLPKWNLNSF-AEHVVFMLRD 271
Query: 236 NFEHLRKTMPLIWQEKERIEKALNVK---------SDANF-FIKY-VGDAKKAVEE--LK 282
+ +++ + ++R+E A + S NF F++ VG AV + L
Sbjct: 272 HGPEYARSLHQV--RRDRLEMAAQLSALPGLTVYPSQGNFLFVRLPVGAEGTAVRDRMLT 329
Query: 283 KRGILVRDC-TSFGLPG-YIRFSVRRAEENERLVQALKDL 320
+ +LVR+C G ++R VR + RLV L+ +
Sbjct: 330 EHRVLVRECGNKIGSSSRFLRLVVRPQADVRRLVSGLEQV 369
>sp|O06591|HIS8_MYCTU HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|7434115|pir||B70544 probable
histidinol-phosphate aminotransferase - Mycobacterium
tuberculosis (strain H37RV) >gi|2117237|emb|CAB09094.1|
(Z95586) hisC [Mycobacterium tuberculosis]
Length = 380
Score = 85.4 bits (208), Expect = 8e-16
Identities = 91/355 (25%), Positives = 151/355 (41%), Gaps = 59/355 (16%)
Query: 22 IDFSASVNPYPPE--WVDEMFKRAREISFSYPYYEE-----LEDELSELLNEEITITAGI 74
+ + + NP+PP VD++ + RE + Y + L +L+ L + I G+
Sbjct: 34 VRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLAGYLTAQTGIQLGV 93
Query: 75 TE---------------------GLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKII 113
G +G + II T+ E+ +R +
Sbjct: 94 ENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDF--- 150
Query: 114 KGSNEPEKLAELVENN-SVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFID 172
G + +A +V+ VVF +PNNP G+ + +L L+D + ++DEA+ +
Sbjct: 151 -GLDVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAP---GIAIVDEAYGE 206
Query: 173 FVKDAKSPE-----GENIVKLRTFTKSYGLPGIRVGYIIGFR---DAFRSVRMPWSIGST 224
F + +V RT +K++ G R+GY+I DA VR+P+ + S
Sbjct: 207 FSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRLGYLIATPAVIDAMLLVRLPYHLSSV 266
Query: 225 GVAFLEFLIEDNFEHLRKTMPLIWQEKERIEKALN------VKSDANFFI-KYVGDAKKA 277
A + + + L LI E+ER+ +LN + SDANF + DA A
Sbjct: 267 TQAAARAALRHSDDTLSSVAALI-AERERVTTSLNDMGFRVIPSDANFVLFGEFADAPAA 325
Query: 278 VEELKKRGILVRDCTSFGLPGYIRFSVRRAEENERLVQA----LKDLSPELLAPV 328
+ GIL+RD G+PGY+R + AEEN+ ++A DL P +PV
Sbjct: 326 WRRYLEAGILIRDV---GIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPV 377
>sp|P10369|HIS8_SALTY HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE)
Length = 359
Score = 83.1 bits (202), Expect = 4e-15
Identities = 71/279 (25%), Positives = 132/279 (46%), Gaps = 28/279 (10%)
Query: 66 EEITITAGITEGLYL-LGILALRGRKVIIP-RHTYGEYERVARIFNAK------IIKGSN 117
E++ ++ G EG+ L + G+ I+ TYG Y A + +
Sbjct: 79 EQVLVSRGADEGIELVIRAFCEPGKDAILYCPPTYGMYSVSAETIGVERRTVPALENWQL 138
Query: 118 EPEKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDA 177
+ + +++ ++ VVF C+PNNP G+ P++L+ L++ KA++V DEA+I+F A
Sbjct: 139 DLQGISDNLDGTKVVFVCSPNNPTGQLINPQDLRTLLELTRG-KAIVVADEAYIEFCPQA 197
Query: 178 KSP----EGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFR---SVRMPWSIGSTGVAFL- 229
E ++V LRT +K++ L G+R G+ + + V P+ + ST VA +
Sbjct: 198 TLTGWLVEYPHLVILRTLSKAFALAGLRCGFTLANEEVINLLLKVIAPYPL-STPVADIA 256
Query: 230 -EFLIEDNFEHLRKTMPLIWQEKERIEKALN--------VKSDANFFIKYVGDAKKAVEE 280
+ L +R + QE++ + AL S+ N+ + + +
Sbjct: 257 AQALCPQGINAMRDRVAQTVQERQYLVNALQQTACVEHVFDSETNYILARFTASSSVFKS 316
Query: 281 LKKRGILVRDCTSF-GLPGYIRFSVRRAEENERLVQALK 318
L +GI++RD L G +R +V +EN+R++ AL+
Sbjct: 317 LWDQGIILRDQNKQPSLSGCLRITVGTRQENQRVIDALR 355
>sp|P16246|HIS8_STRCO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|80723|pir||JQ0637 histidinol-phosphate
transaminase (EC 2.6.1.9) - Streptomyces coelicolor
>gi|153297|gb|AAA26756.1| (M31628) histidinol-phosphate
amidotransferase (hisC) (gtg start codon) (EC 2.6.1.9)
[Streptomyces coelicolor] >gi|5596798|emb|CAB51445.1|
(AL096884) histidinol-phosphate aminotransferase
[Streptomyces coelicolor A3(2)]
Length = 369
Score = 81.9 bits (199), Expect = 9e-15
Identities = 94/348 (27%), Positives = 159/348 (45%), Gaps = 56/348 (16%)
Query: 22 IDFSASVNPYP-PE-WVDEMFKRAREISFSYPYYEELED-ELSELLNEEITITAGITEGL 78
+ + + NPYP PE V+ + +R RE + Y + + EL L +T T+G L
Sbjct: 29 VRLNTNENPYPLPEALVERIAERVREAARDLNRYPDRDAVELRTQLARYLTDTSG--HPL 86
Query: 79 YLLGILALRGRKVIIPR--HTYGEYERVARIFNAK------IIKGSNE------------ 118
+ + A G +I + T+G R A F I +G+
Sbjct: 87 DVSNVWAANGSNEVIQQLLQTFGGPGRTAIGFEPSYSMHGLIARGTGTGWISGPRHEDFT 146
Query: 119 ---PEKLAELVENN-SVVFFCNPNNPDGRYYTPRELKPLIDAVEDRK-ALLVLDEAFIDF 173
P + E+ VVF PNNP G + L +A + K +++V+DEA+I+F
Sbjct: 147 IDVPAATRAIDEHRPDVVFITTPNNPTGTAVPAETVLALYEAAQAAKPSMVVVDEAYIEF 206
Query: 174 VKDAKSP---EGE-NIVKLRTFTKSYGLPGIRVGYIIGFR---DAFRSVRMPWSIG---- 222
A +G N+V RT +K++G G+R+GY+ DA + VR+P+ +
Sbjct: 207 SHGASLLPLLDGRPNLVVSRTMSKAFGAAGLRLGYLAAHPAVVDAVQLVRLPYHLSAVTQ 266
Query: 223 STGVAFLEFLIEDNFEHLRKTMPLIWQEKERIEKALN------VKSDANFF-IKYVGDAK 275
+T +A LE + + L K + + E++R+ L +SDANF D+
Sbjct: 267 ATALAALE-----HTDTLLKYVEQLKTERDRLVAELRAIGYAVTESDANFVQFGRFADSH 321
Query: 276 KAVEELKKRGILVRDCTSFGLPGYIRFSVRRAEENERLVQALKDLSPE 323
++ RG+LVRD G+PG++R + EEN+ + A++++ E
Sbjct: 322 ATWRKILDRGVLVRD---NGVPGWLRVTAGTPEENDAFLDAVREVKKE 366
>sp|Q9ZHE5|HIS8_BUCAP HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|4038316|gb|AAC97356.1| (AF067228)
histidinolphosphate aminotransferase [Buchnera
aphidicola]
Length = 355
Score = 81.5 bits (198), Expect = 1e-14
Identities = 86/288 (29%), Positives = 135/288 (46%), Gaps = 37/288 (12%)
Query: 63 LLNEEITITAGITEGLYLLGILALRGRK--VIIPRHTYGEYERVARIFNAKI-----IKG 115
LLN +I +T G EG+ LL K +I TY Y A+I N +I K
Sbjct: 72 LLNNQILVTRGADEGIELLIKAFCEPGKDAIIYCPPTYDMYAINAKIANVEIKEIPTFKN 131
Query: 116 SNEPEKLAELVENNSV--VFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDF 173
+ + + L N V ++ CNPNNP G + +LK L+ V ++L+++DEA+I+F
Sbjct: 132 TWKIDLLNIRSNLNKVKLIYICNPNNPTGNIVSQEDLKSLL-KVTLGQSLVIIDEAYIEF 190
Query: 174 VKDAKSPEGE---------NIVKLRTFTKSYGLPGIRVGYIIGFR---DAFRSVRMPWSI 221
SP+ N++ LRT +K++ L GIR G+ + + D V P+ I
Sbjct: 191 -----SPKNSMVNYLKTFPNLIILRTLSKAFALAGIRCGFTLAQKEVIDILHKVISPYPI 245
Query: 222 GS----TGVAFLEFLIEDNFEH--LRKTMPLIW--QEKERIEKALNV-KSDANFFIKYVG 272
+ V LE D+ ++ L+ M IW E ++I V S AN+ +
Sbjct: 246 STLIADIAVQSLEKKAIDDMKNRVLKLNMNRIWLIDELKKISCVKKVFDSHANYILVEFY 305
Query: 273 DAKKAVEELKKRGILVRDCT-SFGLPGYIRFSVRRAEENERLVQALKD 319
KK + L ++GI++R+ L +R S+ E RLVQ LK+
Sbjct: 306 MFKKIFQSLWQKGIILRNQNHKNNLKNCLRISIGSKSECMRLVQELKN 353
>gb|AAK41178.1| Aspartate aminotransferase (aspB-2) [Sulfolobus solfataricus]
Length = 402
Score = 79.6 bits (193), Expect = 5e-14
Identities = 59/240 (24%), Positives = 115/240 (47%), Gaps = 45/240 (18%)
Query: 15 RRNEIKLIDFSASVNPYPPEWVDEMFKRARE-----ISFSYPYY------EELEDELSEL 63
+ +IK+IDF P FKR R+ + + +Y +EL +++++
Sbjct: 31 KTKKIKIIDFGIGQPDLPT------FKRIRDAAKEALDQGFTFYTSAFGIDELREKIAQY 84
Query: 64 LN---------EEITITAGITEGLYLLGILALR-GRKVIIPRHTYGEYERVARIFNAKII 113
LN EE+ +T G L+L+ IL + +VI+P ++ Y V ++ K I
Sbjct: 85 LNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYAEVVKLLGGKPI 144
Query: 114 ----KGSNEP-------EKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKA 162
K S E + +++ + ++ F NP+NP G ++P ++K ++D D K
Sbjct: 145 YANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVKKIVDISRDNKI 204
Query: 163 LLVLDEAFIDFVKDAK-------SPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSV 215
+L+ DE + +FV + K S + ++ + F+K++ + G R+GYI+ R+ + +
Sbjct: 205 ILLSDEIYDNFVYEGKMRSTLEDSDWRDFLIYVNGFSKTFSMTGWRLGYIVAKREIIQKM 264
>sp|P14909|AAT_SULSO ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|99262|pir||S07088 aspartate transaminase (EC
2.6.1.1) - Sulfolobus solfataricus
>gi|809765|emb|CAA34514.1| (X16505) aspartate
aminotransferase (AA 1-402) [Sulfolobus solfataricus]
>gi|226717|prf||1604198A Asp aminotransferase
[Sulfolobus solfataricus]
Length = 402
Score = 79.6 bits (193), Expect = 5e-14
Identities = 59/240 (24%), Positives = 115/240 (47%), Gaps = 45/240 (18%)
Query: 15 RRNEIKLIDFSASVNPYPPEWVDEMFKRARE-----ISFSYPYY------EELEDELSEL 63
+ +IK+IDF P FKR R+ + + +Y +EL +++++
Sbjct: 31 KTKKIKIIDFGIGQPDLPT------FKRIRDAAKEALDQGFTFYTSAFGIDELREKIAQY 84
Query: 64 LN---------EEITITAGITEGLYLLGILALR-GRKVIIPRHTYGEYERVARIFNAKII 113
LN EE+ +T G L+L+ IL + +VI+P ++ Y V ++ K I
Sbjct: 85 LNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYAEVVKLLGGKPI 144
Query: 114 ----KGSNEP-------EKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKA 162
K S E + +++ + ++ F NP+NP G ++P ++K ++D D K
Sbjct: 145 YANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVKKIVDISRDNKI 204
Query: 163 LLVLDEAFIDFVKDAK-------SPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSV 215
+L+ DE + +FV + K S + ++ + F+K++ + G R+GYI+ R+ + +
Sbjct: 205 ILLSDEIYDNFVYEGKMRSTLEDSDWRDFLIYVNGFSKTFSMTGWRLGYIVAKREIIQKM 264
>pir||S45613 aspartate aminotransferase - Sulfolobus solfataricus
Length = 401
Score = 79.6 bits (193), Expect = 5e-14
Identities = 59/240 (24%), Positives = 115/240 (47%), Gaps = 45/240 (18%)
Query: 15 RRNEIKLIDFSASVNPYPPEWVDEMFKRARE-----ISFSYPYY------EELEDELSEL 63
+ +IK+IDF P FKR R+ + + +Y +EL +++++
Sbjct: 30 KTKKIKIIDFGIGQPDLPT------FKRIRDAAKEALDQGFTFYTSAFGIDELREKIAQY 83
Query: 64 LN---------EEITITAGITEGLYLLGILALR-GRKVIIPRHTYGEYERVARIFNAKII 113
LN EE+ +T G L+L+ IL + +VI+P ++ Y V ++ K I
Sbjct: 84 LNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYAEVVKLLGGKPI 143
Query: 114 ----KGSNEP-------EKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKA 162
K S E + +++ + ++ F NP+NP G ++P ++K ++D D K
Sbjct: 144 YANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVKKIVDISRDNKI 203
Query: 163 LLVLDEAFIDFVKDAK-------SPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSV 215
+L+ DE + +FV + K S + ++ + F+K++ + G R+GYI+ R+ + +
Sbjct: 204 ILLSDEIYDNFVYEGKMRSTLEDSDWRDFLIYVNGFSKTFSMTGWRLGYIVAKREIIQKM 263
>emb|CAA96498.1| (Z71971) hypothetical protein [Paracoccus denitrificans]
Length = 367
Score = 78.4 bits (190), Expect = 1e-13
Identities = 93/353 (26%), Positives = 153/353 (42%), Gaps = 41/353 (11%)
Query: 5 VRFSTHHGGARR-----NEIKLIDFSASVNPY-PPEWVDEMFKRAREISFSYPYYEELE- 57
+ S + GGA + N +KL S++ NP+ P + E RA YP +
Sbjct: 15 MEISLYEGGASKVAGVENVVKL---SSNENPFGPSDKAREAMIRAAHGLHRYPNTDHAGL 71
Query: 58 ----DELSELLNEEITITAGITEGLYLL-GILALRGRKVIIPRHTYGEYERVARIFNAKI 112
E+ L + I G E ++ L A G +V+ H + Y A A
Sbjct: 72 RGAIGEVHGLDPDRIICGVGSDEIIHFLCQAYAGPGTEVLFTEHGFLMYRISAHAAGAIP 131
Query: 113 IKGSNEPEKLAEL------VENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVL 166
++ + E +++ ++ ++F NP NP G EL+ L AV R AL+V
Sbjct: 132 VQVA-ERDRVTDIDALIAGATPTRLIFVANPKNPTGTMVGLPELERLARAVPQRIALVV- 189
Query: 167 DEAFIDFVKD----AKSPEG-ENIVKLRTFTKSYGLPGIRVGYIIGFR---DAFRSVRMP 218
D A+ ++V D A+ + N+ RTF+K YGL G+RVG+ G R D +R P
Sbjct: 190 DAAYAEYVGDYDGGAQLAQALPNVFMTRTFSKIYGLGGLRVGWGYGPREIVDVLNRIRAP 249
Query: 219 WSIGSTGVAFLEFLIEDNFEHLRKTMP-----LIWQEKERIEKAL-NVKSDANFFIKYVG 272
+++ + + E + D EH+ + W + EK + + S ANF +
Sbjct: 250 FNLSNVALEGAEAAMRDR-EHIARCQAENARMRAWLAEALAEKGVPSDTSCANFILARFA 308
Query: 273 DAKKA---VEELKKRGILVRDCTSFGLPGYIRFSVRRAEENERLVQALKDLSP 322
DA+ A E LK +G++VR +GLP +R ++ R+ + P
Sbjct: 309 DAETAGACDEYLKTQGLIVRRVAGYGLPHCLRITIGDEASCRRVAHVIASTWP 361
>pir||S77354 histidinol-phosphate aminotransferase hisC-1 - Synechocystis sp.
(strain PCC 6803) >gi|1652536|dbj|BAA17457.1| (D90906)
histidinol-phosphate aminotransferase [Synechocystis
sp.]
Length = 352
Score = 78.4 bits (190), Expect = 1e-13
Identities = 98/349 (28%), Positives = 154/349 (44%), Gaps = 67/349 (19%)
Query: 21 LIDFSASVNPY-PPEWVDEMFKRAREISFSYP--YYEELEDELSE---LLNEEITITAGI 74
L+DFSAS+NP PP V + A YP Y L +++ L + + G
Sbjct: 9 LLDFSASINPLGPPASVLAAIESALPALRHYPDPQYIHLRQAIADHHQLSMDWVLPGNGS 68
Query: 75 TEGLYLLG--ILALRGRKVIIPRHTYGEYERVARIFNAKI---------------IKGSN 117
E L L G +L V+ P +G+Y R R A++ ++ +
Sbjct: 69 AELLTLAGRTFASLDCTYVVGP--AFGDYGRSWRGAGAELKTIPWQVDQPWPWRKLRSPS 126
Query: 118 EPEKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVK-- 175
E + + ++ + NP+NP G E+ L+ + ++LDEAF+DF+
Sbjct: 127 EIANTSAVQSSHHGLILNNPHNPSGTLLAREEILALLPHYQ----WVLLDEAFMDFLPPG 182
Query: 176 DAKSPEGE-----NIVKLRTFTKSYGLPGIRVGYIIGFRD---AFRSVRMPWSIG----S 223
+ +S G+ N++ LR+ TK Y LPG+R+GY + D +++ R PW + +
Sbjct: 183 EEQSLVGDLEKHPNLIILRSLTKFYRLPGLRLGYALAHPDLLAQWQAWRDPWPVNVLAEA 242
Query: 224 TGVAFLEFLIEDNFEHLRKTMPLIWQEKERIEKALN-----------VKSDANF-FIKYV 271
+A LE E R+ L+WQ AL + S NF +K
Sbjct: 243 AAIASLE------AEEFRQ---LVWQWLPPARSALQQDLASLPGLFPLPSQTNFLLVKTT 293
Query: 272 GDAKKAVEE-LKKRGILVRDCTSFGLPG--YIRFSVRRAEENERLVQAL 317
A + EE L K IL+RDC SF G + R +VR +N++L QAL
Sbjct: 294 IPAPELQEELLTKCQILIRDCLSFPELGEDFFRVAVRTMADNQKLTQAL 342
>pir||D81289 probable aminotransferase Cj1436c [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6968865|emb|CAB73860.1|
(AL139078) putative aminotransferase [Campylobacter
jejuni]
Length = 390
Score = 78.4 bits (190), Expect = 1e-13
Identities = 70/273 (25%), Positives = 125/273 (45%), Gaps = 39/273 (14%)
Query: 88 GRKVIIPRHTYGEYERVAR----IFNAKIIKGSNEPEKLAELV-----ENNSVVFFCNPN 138
G+K+I+ T+ Y A+ + ++ K N + + EN V NPN
Sbjct: 120 GKKIIVNIPTFSSYYEFAKSETNVVYYQLSKEDNYNLNIEHYLNFVKNENPDSVVLINPN 179
Query: 139 NPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPEGENI----------VKL 188
NPDG Y +L+ ++ ++ K +++DE+FI F + K G NI + +
Sbjct: 180 NPDGGYINYEKLRYILSELKYVKN-IIIDESFIHFAYENKDYNGINIEYLFKEFHNTIII 238
Query: 189 RTFTKSYGLPGIRVGYIIGFRDAFRSVRMP---WSIGSTGVAFLEFLIEDNF-------- 237
++ +K +G+ GIR+GY I D R + W+ FL + NF
Sbjct: 239 KSMSKDFGVAGIRIGYAIMSEDKIRGLLKNGYLWNSSGLSEYFLRLYVRKNFFDEYDKVR 298
Query: 238 -EHLRKTMPLIWQEKERIEKALNVKSDANFFIKYVGDAKKAVE----ELKKRGILVRDCT 292
E++++T +++ I++ S ANF + + D + + L K GI +R C
Sbjct: 299 REYIQETQ-TFFRKLSGIKQFKVYPSMANFALVELLDGSSSTDFVAKMLIKYGIYMRTCN 357
Query: 293 -SFGLPG-YIRFSVRRAEENERLVQALKDLSPE 323
GL G +IR + R EEN+ +++++ D+ E
Sbjct: 358 DKIGLEGEFIRIASRTLEENDMVLKSICDVFKE 390
>emb|CAC11142.1| (AJ250581) NikT protein [Streptomyces tendae]
Length = 440
Score = 78.0 bits (189), Expect = 1e-13
Identities = 89/316 (28%), Positives = 138/316 (43%), Gaps = 34/316 (10%)
Query: 29 NPY-PPEWVDEMFKRAREISFSYP--YYEELEDELSE---LLNEEITITAG-ITEGLYLL 81
NP+ PP V + RA + YP E L L+ L + + + AG IT LL
Sbjct: 125 NPFQPPASVLDAITRAAAEANRYPDPACEALRAALARHYGLFPDRVAVGAGSITLLQALL 184
Query: 82 GILALRGRKVIIPRHTYGEYERVA-----RIFNAKIIKGSNEPEKLAELV-ENNSVVFFC 135
+ A G V ++ YE +A R + + ++ + LA V E+ +V C
Sbjct: 185 TVTAGPGAAVAYSWPSFDGYEVLADLAGFRTVRVPLAEDGHDLDALAAAVDEHTRLVLLC 244
Query: 136 NPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKS-----PEGENIVKLRT 190
NPNNP G +L +DAV R L+VLDEA+ ++ +D N++ RT
Sbjct: 245 NPNNPTGTASGEADLLRFLDAVP-RTCLVVLDEAYCEYARDPGLGARLLTSWPNLIVART 303
Query: 191 FTKSYGLPGIRVGYII---GFRDAFRSVRMPWSIGSTGVAFLEFLIEDNFEHLRKTMPLI 247
F+K+YGL G+RVGY++ G + MP S+ A + E L +
Sbjct: 304 FSKAYGLAGMRVGYLLAEPGLISRVHRMVMPLSVSDVAQAAAVASLAAEKELLGRVRETA 363
Query: 248 WQEKERIEKALNV------KSDANFFIKYVG-DAKKAVEELKKRGILVRDCTSFGLPGYI 300
E++R+ AL S+ANF +G A++ G+ VR G +
Sbjct: 364 -AERDRVRAALLALGFDVPPSEANFLWLPLGARAEEFAAACASAGVAVRPYPGDG----V 418
Query: 301 RFSVRRAEENERLVQA 316
R + AE+N+ + A
Sbjct: 419 RVTTGTAEDNDAFLAA 434
>sp|P06986|HIS8_ECOLI HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|2117762|pir||I73527
histidinol-phosphate aminotransferase - Escherichia coli
>gi|7427963|pir||XNECHC histidinol-phosphate
transaminase (EC 2.6.1.9) [validated] - Escherichia coli
>gi|509819|gb|AAA19743.1| (U02071) histidinol-phosphate
aminotransferase [Escherichia coli]
>gi|1736699|dbj|BAA15852.1| (D90840)
Histidinol-phosphate aminotransferase (EC 2.6.1.9)
(Imidazole acetol- phosphate transaminase). [Escherichia
coli] >gi|1788332|gb|AAC75082.1| (AE000293)
histidinol-phosphate aminotransferase [Escherichia coli
K12]
Length = 356
Score = 77.6 bits (188), Expect = 2e-13
Identities = 69/279 (24%), Positives = 130/279 (45%), Gaps = 28/279 (10%)
Query: 66 EEITITAGITEGLYLLGILALRGRK--VIIPRHTYGEYERVARIFNAK------IIKGSN 117
E++ ++ G EG+ LL K ++ TYG Y A + +
Sbjct: 76 EQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLDNWQL 135
Query: 118 EPEKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDA 177
+ + +++ ++ VV+ C+PNNP G+ P++ + L++ KA++V DEA+I+F A
Sbjct: 136 DLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRTLLELTRG-KAIVVADEAYIEFCPQA 194
Query: 178 K----SPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFR---SVRMPWSIGSTGVAFL- 229
E ++ LRT +K++ L G+R G+ + + V P+ + ST VA +
Sbjct: 195 SLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPL-STPVADIA 253
Query: 230 -EFLIEDNFEHLRKTMPLIWQEKERIEKALN--------VKSDANFFIKYVGDAKKAVEE 280
+ L +R+ + I E+E + AL S+ N+ + + +
Sbjct: 254 AQALSPQGIVAMRERVAQIIAEREYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKS 313
Query: 281 LKKRGILVRDCTSF-GLPGYIRFSVRRAEENERLVQALK 318
L +GI++RD L G +R +V EE++R++ AL+
Sbjct: 314 LWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALR 352
>sp|P34037|HIS8_ZYMMO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|762852|gb|AAC41445.1| (L36343)
imidazole acetol phosphate aminotransferase [Zymomonas
mobilis] >gi|1095289|prf||2108319A imidazole acetol
phosphate aminotransferase [Zymomonas mobilis]
Length = 369
Score = 77.6 bits (188), Expect = 2e-13
Identities = 75/282 (26%), Positives = 130/282 (45%), Gaps = 31/282 (10%)
Query: 73 GITEGLYLL-GILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPEK------LAEL 125
G E L+L G A + +V+ PR+++ Y AR A ++ ++ + L +
Sbjct: 90 GSDEILHLAAGAYAGQDDEVLYPRYSFSVYPLAARRVGATPVEAPDDDYRCSVDALLKAV 149
Query: 126 VENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPEG--- 182
VVF NPNNP G + T E++ L + + R LLV+D+A+ +++ D + +G
Sbjct: 150 TPRTRVVFIANPNNPTGTWITRAEVEKLHNGL-PRNCLLVIDQAYAEYL-DPECDDGALA 207
Query: 183 -----ENIVKLRTFTKSYGLPGIRVGYIIG---FRDAFRSVRMPWSIGSTG----VAFLE 230
+N++ RTF+K YGL R+G+ DA +R P+++ G VA LE
Sbjct: 208 LAKNTKNVLVTRTFSKIYGLAAERIGWAYACPEIIDALNRIRAPFNVTIAGQKAAVAALE 267
Query: 231 --FLIEDNFEHLRKTMPLIWQEKERIEKA--LNVKSDANF-FIKYVGD--AKKAVEELKK 283
I+++F+H +K L+ + + + S ANF + + G AK A + L
Sbjct: 268 DQAFIQNSFKHSKKVAWLVENQMALLSNVGIRVIPSSANFTLLLFEGSLTAKTAYKALMD 327
Query: 284 RGILVRDCTSFGLPGYIRFSVRRAEENERLVQALKDLSPELL 325
G R LP +R ++ + + + L L + L
Sbjct: 328 HGYTTRWLPGQRLPHALRITIGSEKHMQDVAGILTSLVRQAL 369
>dbj|BAA77744.1| (AB008676) histidinol-phosphate aminotransferase [Escherichia coli]
Length = 356
Score = 77.3 bits (187), Expect = 2e-13
Identities = 69/279 (24%), Positives = 130/279 (45%), Gaps = 28/279 (10%)
Query: 66 EEITITAGITEGLYLLGILALRGRK--VIIPRHTYGEYERVARIFNAK------IIKGSN 117
E++ ++ G EG+ LL K ++ TYG Y A + +
Sbjct: 76 EQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLENWQL 135
Query: 118 EPEKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDA 177
+ + +++ ++ VV+ C+PNNP G+ P++ + L++ KA++V DEA+I+F A
Sbjct: 136 DLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRTLLELTRG-KAIVVADEAYIEFCPQA 194
Query: 178 K----SPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFR---SVRMPWSIGSTGVAFL- 229
E ++ LRT +K++ L G+R G+ + + V P+ + ST VA +
Sbjct: 195 SLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPL-STPVADIA 253
Query: 230 -EFLIEDNFEHLRKTMPLIWQEKERIEKALN--------VKSDANFFIKYVGDAKKAVEE 280
+ L +R+ + I E+E + AL S+ N+ + + +
Sbjct: 254 AQALSPQGIIAMRERVAQIIAEREYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKS 313
Query: 281 LKKRGILVRDCTSF-GLPGYIRFSVRRAEENERLVQALK 318
L +GI++RD L G +R +V EE++R++ AL+
Sbjct: 314 LWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALR 352
>pir||XNEBHC histidinol-phosphate transaminase (EC 2.6.1.9) - Salmonella
typhimurium >gi|47723|emb|CAA31824.1| (X13464) hisC ORF
(AA 1-359) [Salmonella typhimurium]
Length = 359
Score = 76.5 bits (185), Expect = 4e-13
Identities = 69/279 (24%), Positives = 130/279 (45%), Gaps = 28/279 (10%)
Query: 66 EEITITAGITEGLYL-LGILALRGRKVIIP-RHTYGEYERVARIFNAK------IIKGSN 117
E++ ++ G EG+ L + G+ I+ TYG Y A + +
Sbjct: 79 EQVLVSRGADEGIELVIRAFCEPGKDAILYCPPTYGMYSVSAETIGVERRTVPALENWQL 138
Query: 118 EPEKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDA 177
+ + +++ ++ VVF C+PNNP G+ P++L+ L++ KA++V DEA+I+F A
Sbjct: 139 DLQGISDNLDGTKVVFVCSPNNPTGQLINPQDLRTLLELTRG-KAIVVADEAYIEFCPQA 197
Query: 178 KSP----EGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFR---SVRMPWSIGSTGVAFL- 229
E ++V LRT +K++ L G+R G+ + + V P+ + ST VA +
Sbjct: 198 TLTGWLVEYPHLVILRTLSKAFALAGLRRGFTLANEEVINLLLKVIAPYPL-STPVADIA 256
Query: 230 -EFLIEDNFEHLRKTMPLIWQEKERIEKALN--------VKSDANFFIKYVGDAKKAVEE 280
+ +R + QE++ + AL S+ N+ + + +
Sbjct: 257 AQASCPQESNAMRDRVAQTVQERQYLVNALQQTACVEHVFDSETNYILARFTASSSVFKS 316
Query: 281 LKKRGILVRDCTSF-GLPGYIRFSVRRAEENERLVQALK 318
L +GI++RD L G +R +V +EN+ ++ AL+
Sbjct: 317 LWDQGIILRDQNKQPSLSGCLRITVGTRQENQPVIDALR 355
>gi|6322075 histidinol-phosphate aminotransferase; His5p [Saccharomyces
cerevisiae] >gi|729721|sp|P07172|HIS8_YEAST
HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE
ACETOL-PHOSPHATE TRANSAMINASE) >gi|630079|pir||S48456
histidinol-phosphate transaminase (EC 2.6.1.9) - yeast
(Saccharomyces cerevisiae) >gi|558690|emb|CAA86264.1|
(Z38125) his5, len: 385, CAI: 0.21, HIS8_YEAST P07172
HISTIDINOL-PHOSPHATE AMINOTRANSFERASE [Saccharomyces
cerevisiae]
Length = 385
Score = 76.5 bits (185), Expect = 4e-13
Identities = 76/301 (25%), Positives = 147/301 (48%), Gaps = 40/301 (13%)
Query: 57 EDELSELLNEEITITAGITEGL-YLLGILALRGR-KVIIPRHTYGEYERVARIFNAKIIK 114
+ E+ L + + + G E + ++ + G+ K+++ TY Y A I + ++++
Sbjct: 79 DPEVKPLTADNLCLGVGSDESIDAIIRACCVPGKEKILVLPPTYSMYSVCANINDIEVVQ 138
Query: 115 -------GS--NEPEKLAELVENNSVV---FFCNPNNPDGRYYTPRELKPLIDAVEDRKA 162
GS + E + +++N+S++ F +P NP G ++ ++ ++
Sbjct: 139 CPLTVSDGSFQMDTEAVLTILKNDSLIKLMFVTSPGNPTGAKIKTSLIEKVLQNWDN--G 196
Query: 163 LLVLDEAFIDFVKDAKSP---EGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFR---SVR 216
L+V+DEA++DF + +P + N+V L+T +KS+GL GIR+G + R +++
Sbjct: 197 LVVVDEAYVDFCGGSTAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMK 256
Query: 217 MPWSIGSTGVAF-LEFLIEDNFEHLRKTMPLIWQEKERIEKALNVKS----------DAN 265
P++I S + L+ + + N + + T +I +EK R+ K L DAN
Sbjct: 257 APYNISSLASEYALKAVQDSNLKKMEATSKIINEEKMRLLKELTALDYVDDQYVGGLDAN 316
Query: 266 FFIKYV--GD---AKKAVEEL-KKRGILVR-DCTSFGLPGYIRFSVRRAEENERLVQALK 318
F + + GD AKK +L + G++VR G G +R +V EEN L++ K
Sbjct: 317 FLLIRINGGDNVLAKKLYYQLATQSGVVVRFRGNELGCSGCLRITVGTHEENTHLIKYFK 376
Query: 319 D 319
+
Sbjct: 377 E 377
>emb|CAA27150.1| (X03416) hisC protein [Escherichia coli] >gi|41710|emb|CAA31813.1|
(X13462) hisC ORF (AA 1-356) [Escherichia coli]
Length = 356
Score = 75.3 bits (182), Expect = 9e-13
Identities = 69/279 (24%), Positives = 130/279 (45%), Gaps = 28/279 (10%)
Query: 66 EEITITAGITEGLYLLGILALRGRK--VIIPRHTYGEYERVARIFNAK---IIKGSN--- 117
E++ ++ G EG+ LL K ++ TYG Y A + + N
Sbjct: 76 EQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTPDNWQL 135
Query: 118 EPEKLAELVENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDA 177
+ + +++ ++ V+ C+PNNP G+ P++ + L++ KA++V DEA+I+F A
Sbjct: 136 DLQGISDKLDGVKAVYVCSPNNPTGQLINPQDFRTLLELTRG-KAIVVADEAYIEFCPQA 194
Query: 178 K----SPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFR---SVRMPWSIGSTGVAFL- 229
E ++ LRT +K++ L G+R G+ + + V P+ + ST VA +
Sbjct: 195 SLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPL-STPVADIA 253
Query: 230 -EFLIEDNFEHLRKTMPLIWQEKERIEKALN--------VKSDANFFIKYVGDAKKAVEE 280
+ L +R+ + I E+E + AL S+ N+ + + +
Sbjct: 254 AQALSPQGIVAMRERVAQIIAEREYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKS 313
Query: 281 LKKRGILVRDCTSF-GLPGYIRFSVRRAEENERLVQALK 318
L +GI++RD L G +R +V EE++R++ AL+
Sbjct: 314 LWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALR 352
>sp|P55683|Y4WE_RHISN PROBABLE AMINOTRANSFERASE Y4WE >gi|2182694|gb|AAB91912.1|
(AE000103) Y4wE [Rhizobium sp. NGR234]
Length = 368
Score = 74.5 bits (180), Expect = 2e-12
Identities = 63/211 (29%), Positives = 104/211 (48%), Gaps = 31/211 (14%)
Query: 132 VFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSP---EGENIVKL 188
+ NPNNP G + +++ L+ A+ D+ L+VLDEA++DF D+ N++ L
Sbjct: 162 ILLANPNNPTGTFVPIADIESLV-ALSDQ--LVVLDEAYVDFAPDSALRLVNRYSNLLLL 218
Query: 189 RTFTKSYGLPGIRVGYIIGFRDA---FRSVRMPWSIG----STGVAFL--EFLIEDNFEH 239
RTF+KSY GIRVG+ G + R+++ +++ + GV+ L +N H
Sbjct: 219 RTFSKSYAAAGIRVGFGFGHPEVIGRLRNIQNMFNMNVIGHAVGVSILAHRATYNENHRH 278
Query: 240 LRKTMPLIWQEKERIEKALN------VKSDANFFIKYVGDAKKAV---EELKKRGILVRD 290
+R E+ER+ AL+ S ANF + V + V LK++ ILV
Sbjct: 279 IR-------HERERVRVALSRLGFSVTPSHANFLLARVPAGRDGVWWHACLKRKKILVAV 331
Query: 291 CTSFGLPGYIRFSVRRAEENERLVQALKDLS 321
GL IR S+ + + + A++D+S
Sbjct: 332 LPDEGLEDCIRVSIGTKPQMDAFLAAVEDIS 362
>emb|CAA29139.1| (X05650) HIS5 (AA 1-384) [Saccharomyces cerevisiae]
>gi|2358009|gb|AAB68950.1| (AD001531) histidinol
phosphate aminotransferase [Cloning vector pGR8]
>gi|225964|prf||1404370A histidinol phosphate
aminotransferase [Saccharomyces cerevisiae]
Length = 384
Score = 73.7 bits (178), Expect = 3e-12
Identities = 74/300 (24%), Positives = 144/300 (47%), Gaps = 39/300 (13%)
Query: 57 EDELSELLNEEITITAGITEGL-YLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIK- 114
+ E+ L + + + G E + ++ +R K+++ TY A I + ++++
Sbjct: 79 DPEVKPLTADNLCLGVGSDESIDAIIRACCVREEKILVLPPTYSMSSVCANINDIEVVQC 138
Query: 115 ------GS--NEPEKLAELVENNSVV---FFCNPNNPDGRYYTPRELKPLIDAVEDRKAL 163
GS + E + +++N+S++ F +P NP G ++ ++ ++ L
Sbjct: 139 PLIVSDGSFQMDTEAVLTILKNDSLIKLMFVTSPGNPTGAKIKTSLIEKVLQNWDN--GL 196
Query: 164 LVLDEAFIDFVKDAKSP---EGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFR---SVRM 217
+V+DEA++DF + +P + N+V L+T +KS+GL GIR+G + R +++
Sbjct: 197 VVVDEAYVDFCGGSTAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKA 256
Query: 218 PWSIGSTGVAF-LEFLIEDNFEHLRKTMPLIWQEKERIEKALNVKS----------DANF 266
P++I S + L+ + + N + + T +I +EK + K L DANF
Sbjct: 257 PYNISSLASEYALKAVQDSNLKKMEATSKIINEEKMLLLKELTALDYVDDQYVGGLDANF 316
Query: 267 FIKYV--GD---AKKAVEEL-KKRGILVR-DCTSFGLPGYIRFSVRRAEENERLVQALKD 319
+ + GD AKK +L + G++VR G G +R +V EEN L++ K+
Sbjct: 317 LLIRINGGDNVLAKKLYYQLATQSGVVVRFRGNELGCSGCLRITVGTHEENTHLIKYFKE 376
>gi|11499943 aspartate aminotransferase (aspB-1) [Archaeoglobus fulgidus]
>gi|7447820|pir||F69545 probable aspartate transaminase
(EC 2.6.1.1) aspB1 AF2366 [similarity] - Archaeoglobus
fulgidus >gi|2650722|gb|AAB91291.1| (AE001112) aspartate
aminotransferase (aspB-1) [Archaeoglobus fulgidus]
Length = 373
Score = 73.7 bits (178), Expect = 3e-12
Identities = 72/311 (23%), Positives = 130/311 (41%), Gaps = 38/311 (12%)
Query: 38 EMFKRA-REISFSYPYY------EELEDELSELL---NEEITITAGITEGLYLLGILALR 87
E+ +RA R ++ + +Y EEL ++E + + +TAG +E L + +
Sbjct: 47 EVIERACRAMNAGFTHYTSNFGLEELRSAIAERYGVDSSNVMVTAGGSEALLNASLAFIE 106
Query: 88 -GRKVIIPRHTYGEYERVARIFNAKIIKGSN-------EPEKLAELVENN-SVVFFCNPN 138
G KV+IP + Y A++ +I++ + EKL E+++ N SV+F PN
Sbjct: 107 EGSKVVIPSPNFLSYFTYAKMCGGQIVQLRTHNNGFLPDVEKLNEIIDRNVSVIFLNYPN 166
Query: 139 NPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSPE---GENIVKLRTFTKSY 195
NP G ++ + +++ D KA++V DE + D K EN+V + F+KS
Sbjct: 167 NPTGAVIDEKDARAVVEIAADNKAIVVSDEIYDQIYYDVKPTSLAGYENVVCVNGFSKSL 226
Query: 196 GLPGIRVGYIIG---FRDAFRSVRMPWSIGSTGVA-----------FLEFLIEDNFEHLR 241
+ G R+G+ I D V + + A + ++ + R
Sbjct: 227 SMTGWRIGFTIADEKLLDPMLKVHQVNGVCAPAFAQKAVAEVMAERLFDSIVSRMVKEFR 286
Query: 242 KTMPLIWQEKERIEKALNVKSDANFFIKYVGDAKKAVEELKKRGILVRDCTSF--GLPGY 299
+ ++ E +I + + F+ D + E L G+ V F G Y
Sbjct: 287 QRRDYLYSELSKIYDVVKPEGAFYMFVNVNQDCMEYAENLINLGVAVTPGLPFGDGNETY 346
Query: 300 IRFSVRRAEEN 310
+R S + EN
Sbjct: 347 VRISYANSLEN 357
>gb|AAC05838.1| (AF052516) hemolysin erythrocyte lysis protein 2 [Prevotella
intermedia]
Length = 606
Score = 73.0 bits (176), Expect = 5e-12
Identities = 87/344 (25%), Positives = 140/344 (40%), Gaps = 49/344 (14%)
Query: 20 KLIDFSASVNPY--PPEWVDEMFKRAREISFSYPYYEELEDELSEL---LNEEITITAGI 74
KL+DF VNPY P +DE+ + YP + L+ +N+E +
Sbjct: 266 KLLDFCYLVNPYFPPKRMLDEIRANFDTLVTEYPSGMGVNSLLAGKYFGVNQEYIVVGNG 325
Query: 75 TEGLYLLGILALRGR-KVIIPRHTYGEYERVARIFNAKIIKGSNEPEKLAELVENN---- 129
L I +G+ V+ P T+ EY R + N+ L N
Sbjct: 326 AAELIKSLIETTKGKIGVVFP--TFEEYPNRYRKGDIISYVPDNKDYSYNALNLKNFFAD 383
Query: 130 ---SVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKD---------A 177
+ NP+NP G + E+ L R L++DE+F+DF D
Sbjct: 384 KSIQTLLLINPDNPSGNFIPKYEVLELAAWTAKRNIRLIVDESFVDFSDDYYYNSLLNNQ 443
Query: 178 KSPEGENIVKLRTFTKSYGLPGIRVGY-------IIGFRDAFRSVRMPWSIGSTGVAFLE 230
+ +++ +++ +KSYG+PG+R+G +I F S+ W+I S +++
Sbjct: 444 TLEKYKHLFVMKSISKSYGVPGLRLGILASADTEVINFIKKDVSI---WNINSFAEFYMQ 500
Query: 231 FLIEDNFEHLRKTMPLIWQEKERIEKALN-------VKSDANFFIKYVGDAKKAVEE--- 280
+ ++ L+ E+ R K L + S AN+F+ V + E
Sbjct: 501 IFNKYRSDYNIACESLV-AERNRFAKLLKEISWLRVIPSQANYFLCEVKPPYTSTEVAKR 559
Query: 281 -LKKRGILVRDCT---SFGLPGYIRFSVRRAEENERLVQALKDL 320
LK IL++DC S YIR ++R EN RLV A K L
Sbjct: 560 LLKDYAILIKDCNKKQSLTDMNYIRIAIRNEIENNRLVAACKKL 603
>pir||G75271 histidinol-phosphate aminotransferase - Deinococcus radiodurans
(strain R1) >gi|6460276|gb|AAF12000.1|AE002075_4
(AE002075) histidinol-phosphate aminotransferase
[Deinococcus radiodurans]
Length = 361
Score = 73.0 bits (176), Expect = 5e-12
Identities = 76/328 (23%), Positives = 148/328 (44%), Gaps = 33/328 (10%)
Query: 22 IDFSASVNPYPPEWVDEMFKRAREISFSYPY--YEELEDEL--SELLNEE------ITIT 71
+ + N P ++ E+ ++A E ++P+ Y +L + + + E + IT
Sbjct: 31 VPYKLDQNENPYDFPPELKQKAAERMLAHPWNRYPDLHADTLRAAIAGYEGWDAAGVVIT 90
Query: 72 AGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPE-------KLAE 124
G + +L L G+ V+ T+ Y A + A+++ P+ L
Sbjct: 91 PGSNVLIKILTELGGIGQTVLTTDPTFSVYTLEAAMLGAELVLTPLNPDFSLPVEATLQA 150
Query: 125 LVENNSVVFFCN-PNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFV-KDAKS--P 180
L + VF+ P+ P G P +++ +++ + + V+DEA+ + D +
Sbjct: 151 LAAHAPGVFYVTQPHAPTGHSDRPEDVRRVVEVADRLGWVTVIDEAYSQYAGTDYRELVR 210
Query: 181 EGENIVKLRTFTKSYGLPGIRVGYII---GFRDAFRSVRMPWSIGSTGVAFLEFLIEDNF 237
G++++ LRTF+K++GL G+R GY++ + + ++I A +E +E +
Sbjct: 211 AGKHVLSLRTFSKAWGLAGVRAGYLLTNPELAGHLQKLVSAFTINFLTQAVIETALE-HP 269
Query: 238 EHLRKTMPLIWQEKERIEKALN-------VKSDANFFIKYVGDAKKAVEELKKRGILVRD 290
E++R+ + E+ RI A+ S+ NFF+ DA A L + GI+ R
Sbjct: 270 EYMRERVAEAIAERGRIYAAVQGHPTCTIFPSNTNFFLLKTPDADAAYRHLLEHGIVCRR 329
Query: 291 CTSF-GLPGYIRFSVRRAEENERLVQAL 317
GL G +R +V EN+ L+ A+
Sbjct: 330 QDKLRGLDGCLRIAVGTPAENDALIAAI 357
>gb|AAK40774.1| Histidinol-phosphate aminotransferase, putative (hisC-like)
[Sulfolobus solfataricus]
Length = 326
Score = 71.8 bits (173), Expect = 1e-11
Identities = 76/293 (25%), Positives = 141/293 (47%), Gaps = 38/293 (12%)
Query: 23 DFSASVNPYP-PEWVDEMFKRAREISFSYPYY-----EELEDELSEL--LNEEITITAGI 74
DFS ++NP P++++E+ A ++ Y YY E++ ++E+ +NE++ G+
Sbjct: 19 DFSVNLNPMGVPKFIEELINEAVKLKV-YAYYPPQNLREIKGIIAEIYGVNEDLV---GV 74
Query: 75 TEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKIIKGSNEPEKLAELVENNSVVFF 134
G ++++ +P+ Y EY+ F++ +E E + EL N +
Sbjct: 75 FNGAS--EVISILDENFTVPQPNYSEYK-----FHSYYFAEEHEDEFVFEL--NPGRILT 125
Query: 135 CNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAKSP-----EGENIVKLR 189
NPNNP G E++ + + K L+LDE+FID + A+S E N+ +
Sbjct: 126 SNPNNPTGSLIKLDEIEEFLI---NEKNELILDESFID-ISLAESATKLVNEFNNLTIIN 181
Query: 190 TFTKSYGLPGIRVGYIIGFRDAFRSVRMP-WSIGSTGVAFLEFL----IEDNFEHLRKTM 244
+FTKS +PG+R G+ IG + R+P W I S + L + F + + +
Sbjct: 182 SFTKSLAIPGLRFGFSIGHKSKELEKRVPIWRINSITYYVISNLNPKEVRSFFVNSKIKV 241
Query: 245 PLIWQEKERIEKALNV-KSDANFF-IKYVGDAKKAVEELKKR-GILVRDCTSF 294
I+ + + ++K + KS A FF +++ +EL +R +RD ++F
Sbjct: 242 KEIYDKVDGVKKLFKMYKSYAPFFLVEFKIPTSLINDELIRRCKCYIRDASNF 294
>gb|AAK41425.1| Aspartate aminotransferase (aspB-3) [Sulfolobus solfataricus]
Length = 356
Score = 71.4 bits (172), Expect = 1e-11
Identities = 70/277 (25%), Positives = 114/277 (40%), Gaps = 48/277 (17%)
Query: 66 EEITITAGITEGLYLLGILALR-GRKVIIPRHTYGEYERVARIFNAKIIK---GSNEPEK 121
E++ ITAG E Y+ + + G +VI+ Y + + R NAKI N
Sbjct: 67 EDVIITAGGAEANYVTVLSTIEPGDEVIVEMPNYMQIPGLLRGINAKIKYIWLNDNFKLD 126
Query: 122 LAELVE----NNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDA 177
L EL E + NPNNP G + E+K ++D ED + ++ DE + D
Sbjct: 127 LNELNEMVSKKTKAIVITNPNNPTGMALSESEIKGIVDIAEDNQVTIIADEVYRGSEHDG 186
Query: 178 KSPEG-----ENIVKLRTFTKSYGLPGIRVGYIIGFR---DAFRSVRMPWSIGST----G 225
+N + + +K YGLPGIR+G+++ + D S+R SI +
Sbjct: 187 NIRPSFIDLYDNAISTNSMSKVYGLPGIRIGWVVANKELVDKMWSIRDYTSISPSILGQE 246
Query: 226 VAFLEFLIEDNF---------------EHLRKTMPLIWQEKERIEKA---LNVKSDANFF 267
+A+ L ++ + E L + + W E A LNVK+ +F
Sbjct: 247 IAYNVLLEKEKYMDRARRIGLNNIRLLERLISDIDVKWVEPNATVLAYLKLNVKNTYDF- 305
Query: 268 IKYVGDAKKAVEELKKRGILVRDCTSFGLPGYIRFSV 304
+ +K +LV F +PGY+R +
Sbjct: 306 ---------SARLFEKYSVLVNPGECFEMPGYVRIGL 333
>dbj|BAA75925.1| (AB012002) aspartate aminotransferase [Pyrococcus kodakaraensis]
Length = 364
Score = 71.4 bits (172), Expect = 1e-11
Identities = 66/271 (24%), Positives = 119/271 (43%), Gaps = 24/271 (8%)
Query: 55 ELEDELSELLN---EEITITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIF--N 109
EL + ++E +E+ + G L+ +KV + + Y +AR F
Sbjct: 56 ELRERIAEFEGVSADEVIVAPGAK---ILIAAEIASAKKVAVVSPRWNAYSLIARQFWRE 112
Query: 110 AKIIKGSNEPEKLAELVENNSVVFFCN-PNNPDGRYYTPRELKPLIDAVEDRKALLVLDE 168
++IK + + + + E + + N PNNP GR + +E++ L+D E+ ++ DE
Sbjct: 113 VEVIKTTLDERWIPRVEEIKADLIIINYPNNPTGRVLSGKEIRGLLDVAEENGVKVLSDE 172
Query: 169 AFIDFVKDAKSPEGE---NIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSVR--------- 216
+ + +P E N+V ++ F+K Y + G R+GY IG R+ R ++
Sbjct: 173 VYAELSFTRFTPARELYENVVTVKGFSKLYSMTGFRLGYAIGERNEIRRIQRFIESTVTC 232
Query: 217 MPWSIGSTGVAFLEFLIEDNFEHLRKTMPLIWQEKERIEKALNVKSDANF--FIKYVGDA 274
+P + GV LE E E R + + + + V+ + F F++ D
Sbjct: 233 VPPFVQRAGVKALELRDELIKEVRRAYLERVRMASKMLRGFDFVEPEGAFYIFLRTPQDG 292
Query: 275 KKAVEELKKRGILVRDCTSFG-LPGYIRFSV 304
E L RG+ V +FG P +IR S+
Sbjct: 293 MAFAERLLSRGVAVFPGMAFGDYPNFIRISL 323
>emb|CAC11170.1| (AL445063) histidinol-phosphate aminotransferase related protein
[Thermoplasma acidophilum]
Length = 300
Score = 70.6 bits (170), Expect = 2e-11
Identities = 79/279 (28%), Positives = 130/279 (46%), Gaps = 36/279 (12%)
Query: 68 ITITAGITEGLYLLGI-LALRGRKVIIPRHTYGEYERVARIFNAKIIK-GSNEPEKLAEL 125
+ I G+T +Y + + LR +I P + EYE + ++ G ++ E+
Sbjct: 28 VIIGPGLTHFIYRIPAWMGLRRSLIIEPN--FNEYEASLLAYGSRTSSLGLGVLKRNPEI 85
Query: 126 VENN--SVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDAK----- 178
V + +F C+P NP G L+ L + +L +D+AF DFV +
Sbjct: 86 VRSYRPDSIFICSPVNPTGDLVDAGLLRKLSMEMSRMGGILFVDQAFGDFVPEHAEETVR 145
Query: 179 -SPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSVR---MPWSIGSTGVAFLEFLIE 234
+ E N++ R+ TK +P +R+GYI+ F +R PW++ LEF+ +
Sbjct: 146 IAEEMGNVIIGRSLTKILSIPSLRLGYILVSDQVFGMIRDREEPWAVCEPA---LEFVRK 202
Query: 235 DNFEHLRKT-MPLIWQEKERIEKAL-----NVKSD--ANFFI---KYVGDAKKAVEELKK 283
+ + LR T + I +E+ + +AL + D ANF + D KK +L K
Sbjct: 203 ADLKALRDTSLKRIGEERSYLMEALENMGFEILGDPHANFIAFRSPFEIDLKK---QLLK 259
Query: 284 RGILVRDCT---SFGLPGYIRFSVRRAEENERLVQALKD 319
GIL+RD + FG Y R +VR EN L+QAL++
Sbjct: 260 SGILIRDLSDYADFGKNCY-RVAVRGRSENALLIQALRN 297
>sp|P44423|HIS8_HAEIN HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|1074204|pir||E64070
histidinol-phosphate transaminase (EC 2.6.1.9) -
Haemophilus influenzae (strain Rd KW20)
>gi|1573449|gb|AAC22129.1| (U32730) histidinol-phosphate
aminotransferase (hisC) [Haemophilus influenzae Rd]
Length = 367
Score = 70.2 bits (169), Expect = 3e-11
Identities = 67/280 (23%), Positives = 129/280 (45%), Gaps = 26/280 (9%)
Query: 66 EEITITAGITEGLYLLGILALRGRK--VIIPRHTYGEYE---RVARIFNAKIIKGSNEPE 120
E + +T G EG+ L+ ++ ++ TYG Y A + + + +
Sbjct: 88 ENVLVTRGGDEGIELIIHTFCEPKQDAILFCPPTYGMYAVSAETAGVLSKTVPLTDDFQL 147
Query: 121 KLAEL---VENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDA 177
L E+ + + VVF C+PNNP G ++ L+ + KA++V+DEA+I+F +A
Sbjct: 148 NLPEIKNHLNDVKVVFVCSPNNPTGNLLKQSDILDLLQ-ITAGKAIVVVDEAYIEFCPEA 206
Query: 178 K----SPEGENIVKLRTFTKSYGLPGIRVGYIIG---FRDAFRSVRMPWSIGSTGVAFLE 230
++ +RT +K++ L G+R G+++ D V P+ I E
Sbjct: 207 SVINLLKNYPHLAIIRTLSKAFALAGLRCGFVLANPELIDILSKVIAPYPIPVPSADLAE 266
Query: 231 -FLIEDNFEHLRKTMPLIWQEKERIEKALNV--------KSDANFFIKYVGDAKKAVEEL 281
L N ++ + ++ + KAL V +S+AN+ + + + + L
Sbjct: 267 QALRPSNIATVQALTQELLSNRQWLAKALLVLHQVEKVYESEANYLLIKCQNGQAVFKAL 326
Query: 282 KKRGILVRDCT-SFGLPGYIRFSVRRAEENERLVQALKDL 320
++GI++RD + L IR +V E E++V+A+K++
Sbjct: 327 WEQGIILRDQNKTLHLQNCIRITVGTRNECEKVVEAIKEV 366
>pir||E71125 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PH0771
[similarity] - Pyrococcus horikoshii
>gi|3257180|dbj|BAA29863.1| (AP000003) 391aa long
hypothetical aspartate aminotransferase [Pyrococcus
horikoshii]
Length = 391
Score = 70.2 bits (169), Expect = 3e-11
Identities = 77/297 (25%), Positives = 130/297 (42%), Gaps = 40/297 (13%)
Query: 66 EEITITAGITEGLYL-LGILALRGRKVIIPRHTYGEYERVARIFNAKIIK-----GSN-- 117
E + ITAG EG YL L RG +VIIP + Y A++ AK ++ +N
Sbjct: 93 ENVIITAGAYEGTYLAFESLLERGDEVIIPDPAFVSYAEDAKVAEAKPVRIPLREENNFL 152
Query: 118 -EPEKLAELVENNSVVFFCN-PNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFV- 174
+P +L E + N+ + N PNNP G K + D ED ++ DE + F+
Sbjct: 153 PDPNELLEKISKNTRMIVINYPNNPTGATLDKELAKTIADIAEDYNIYILSDEPYEHFIY 212
Query: 175 KDAK-----SPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSVRM--PWSIGSTG-- 225
+DAK EN + +F+K++ + G R+G+++ + + + IG+
Sbjct: 213 EDAKHYPMIKFAPENTILANSFSKTFAMTGWRLGFVVAPSQVIKEMTKLHAYVIGNVASF 272
Query: 226 --VAFLEFLIEDNFEHLRKTMPLIWQEKERI-------EKALNVKSDANFF-----IKYV 271
+A +E L + + M + E+ +I + VK F I
Sbjct: 273 VQIAGIEALRSEESWKAVEEMKKEYNERRKIVVKRLKNMPGIKVKEPKGAFYVFPNISGT 332
Query: 272 GDAKKAVEE--LKKRGILVRDCTSFGL--PGYIRFSVRRAEENERLVQALKDLSPEL 324
G + + E L+K ++V T+FG GY+R S A E+L++A+ + L
Sbjct: 333 GMSSEKFSEWLLEKARVVVIPGTAFGRMGEGYVRISY--ATSKEKLIEAMNRIEKAL 387
>pir||E72507 probable histidinol-phosphate aminotransferase APE2035 - Aeropyrum
pernix (strain K1) >gi|5105733|dbj|BAA81045.1|
(AP000063) 384aa long hypothetical histidinol-phosphate
aminotransferase [Aeropyrum pernix]
Length = 384
Score = 70.2 bits (169), Expect = 3e-11
Identities = 93/352 (26%), Positives = 145/352 (40%), Gaps = 47/352 (13%)
Query: 11 HGGARRNEIKLIDFSASVNPY-PPEWVDEMFKRA--REISFSYPYYEELEDELSEL---- 63
HGG R +D S+ NP PP VD + A R + YP YE L +
Sbjct: 32 HGG--RPPPGALDLSSPSNPLGPPPRVDNIILEAVERGVHTRYPDYEYLGFREAVAGFYR 89
Query: 64 LNEEITITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNAKII---------- 113
++ E I + L ALR R +++ +G++ +A +A I
Sbjct: 90 IDLERVIPLNGAAEILPLAAAALRPRSIVVVEPNFGDHTILA--LSAGIPCHSVQLREAG 147
Query: 114 -KGSNEPEKLAEL---VENNSVVFFCNPNNPDGRYYTPRELKPLIDAVEDRKAL-LVLDE 168
+ S EP + L V S++ NPNNP G +L+ L R AL +V+DE
Sbjct: 148 DRFSLEPGAVCSLPRSVVEGSLIVLSNPNNPTGSAAARGDLRELAACATLRGALAVVVDE 207
Query: 169 AFIDF--VKDAKSPEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRS----VRMPWSIG 222
+F D V+ E ++ R+ TK+ L G+R+G+ A + R PW++
Sbjct: 208 SFADLSRVESVLGSVPEGVIVARSLTKTLALQGLRIGFAYTDDAALAARLDMARQPWNVN 267
Query: 223 STGVAFLEFLIEDNFE----HLRKTMPLIWQEKERIEKALNV------KSDANFFIKYVG 272
S +E L+ D H+ + + I K R+ A++ S A F +
Sbjct: 268 SIAALLVERLLGDMASEVKGHIARAIEAIEGLKPRLYSAVSALGAKPYSSQAPFILVRHR 327
Query: 273 DAKKAVEE--LKKRGILVRDCTSFG--LPGYIRFSVRRAEEN-ERLVQALKD 319
L+ G+ +RD +SF P + R SV E ERL +A+ D
Sbjct: 328 RRNPLFARCLLEAAGVYIRDASSFRHLTPYHSRISVAPGVERLERLQEAILD 379
>sp|P36605|HIS8_SCHPO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|1085851|pir||S41584
histidinol-phosphate transaminase (EC 2.6.1.9) his3 -
fission yeast (Schizosaccharomyces pombe)
>gi|431764|gb|AAA67316.1| (L19523)
imidazoleglycerol-phosphate dehydratase
[Schizosaccharomyces pombe] >gi|1174375|gb|AAA86664.1|
(L19524) imidazoleglycerol-phosphate dehydratase
[Schizosaccharomyces pombe] >gi|2257489|dbj|BAA21386.1|
(AB004534) histidinol-phosphate aminotransferase
[Schizosaccharomyces pombe]
Length = 384
Score = 69.5 bits (167), Expect = 5e-11
Identities = 78/321 (24%), Positives = 143/321 (44%), Gaps = 54/321 (16%)
Query: 51 PYYEELEDELSELLNEEITITAGITEGLYLLG------------ILALRGR-KVIIPRHT 97
P E++ L +L N+E++IT +T +G I + G+ K+++ +
Sbjct: 55 PRQIEVKQRLCDLRNKELSITKPLTPDNICMGVGSDEIIDSLIRISCIPGKDKILMCPPS 114
Query: 98 YGEYERVARIFNAKIIKGSNEPE------KLAELVENNSVV---FFCNPNNPDGRYYTPR 148
YG Y A+I + +++K EP+ + E + +S + F C+P NP +
Sbjct: 115 YGMYTVSAKINDVEVVKVLLEPDFNLNVDAICETLSKDSAIKVFFACSPGNPTAKALKLE 174
Query: 149 ELKPLIDAVEDRKALLVLDEAFIDFVKDAKSP-----EGENIVKLRTFTKSYGLPGIRVG 203
++K +++ ++V+DEA+IDF S E N+ +T +KS+GL GIR+G
Sbjct: 175 DIKKILEH-PTWNGIVVVDEAYIDFSAPDMSALTLVNEYPNLAVCQTLSKSFGLAGIRIG 233
Query: 204 YIIGFR---DAFRSVRMPWSIGS-TGVAFLEFLIEDNFEHLRKTMPLIWQEKERIEKALN 259
+ + + S++ P++I T L+ L + + + I Q++ R+ K L
Sbjct: 234 FCLTSKPIATIMNSLKAPYNISEPTSRLALDALSPQSIDKMHTYRDAIIQQRVRLCKELT 293
Query: 260 VKS---------DANFFI----------KYVGDAKK--AVEELKKRGILVRDCTSFGL-P 297
DANF + K DA K ++ ++VR + L
Sbjct: 294 TIKGMGKIIGGYDANFILIQVLDRPEGGKPSNDAAKYLYLQMATMHKVVVRFRGTEPLCE 353
Query: 298 GYIRFSVRRAEENERLVQALK 318
G +R +V EEN L++ +K
Sbjct: 354 GALRITVGTEEENTILLKTIK 374
>gb|AAF61216.1| (AF224501) putative aminotransferase [Streptomyces ansochromogenes]
Length = 582
Score = 69.1 bits (166), Expect = 7e-11
Identities = 73/297 (24%), Positives = 124/297 (41%), Gaps = 29/297 (9%)
Query: 51 PYYEELEDELSELLNEEITITAGITEGLYLLGILALRGRKVIIPRHTYGEYERVARIFNA 110
P Y L D + + + +TAG GL LL ++++ + + + + A I
Sbjct: 66 PVYGMLADRFG-VDTDSLVLTAGSDPGLNLLTRAFPEVSRIVLHQPNFDGWAKFAAISGC 124
Query: 111 KIIKGSNEPEK-------LAELVENNSVVFFC--NPNNPDGRYYTPRELKPLIDAVEDRK 161
+ + +PE LA + + F P++ G+ + EL L DAV +
Sbjct: 125 VLDPVAPDPETGLFDLRDLARRLRAGAPAFVVVTTPHSFTGQVHGREELAELADAVAEHG 184
Query: 162 ALLVLDEAFIDFVKDAKS-----PEGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFR--- 213
+LLV+D A++ F + + ++V++ TF+KSYGL G R+ + R
Sbjct: 185 SLLVVDTAYLAFTEGGEELVRGLAGLRHVVRVNTFSKSYGLSGARIAVTVAHPATARHLF 244
Query: 214 SVRMPWSIGSTGVAFLEFLIEDN------FEHLRKTMPLIWQEKERIEKALNVKSDANFF 267
+ S+ + VA L +E+ + +R+ E ER + + F
Sbjct: 245 DLDPEGSVSAPAVALLRRSLEEQAVFTAIWADVRRLRERFAAEVERAVPGWHARPSGGNF 304
Query: 268 IKY----VGDAKKAVEELKKRGILVRDCTSF-GLPGYIRFSVRRAEENERLVQALKD 319
+ + DA A L RGI+VRD + GLP +R R R+V AL D
Sbjct: 305 VTWDVPDPADAGAASRHLLGRGIVVRDLSGAPGLPAAVRIRSRNETVVRRVVAALGD 361
>sp|P57202|HIS8_BUCAI HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|10038785|dbj|BAB12820.1| (AP001118)
histidinol-phosphate aminotransferase [Buchnera sp. APS]
Length = 368
Score = 69.1 bits (166), Expect = 7e-11
Identities = 78/283 (27%), Positives = 131/283 (45%), Gaps = 31/283 (10%)
Query: 67 EITITAGITEGLYLLGILALRGRK--VIIPRHTYGEYERVARIFNAKI-----IKGSNEP 119
+I T G EG+ LL K +I TY Y A I +I IK + +
Sbjct: 77 QILATRGADEGIELLIKAFCEPGKDAIIYCPPTYDMYRINATIAGVEIKEIPTIKNTWQL 136
Query: 120 EKLAELVENNSV--VFFCNPNNPDGRYYTPRELKPLIDAVEDRKALLVLDEAFIDFVKDA 177
+ L + + V ++ CNPNNP G + ++L L++ + +AL+V+DEA+I+F +
Sbjct: 137 DLLNIKLNLSRVKLIYICNPNNPTGNIFFKKDLIFLLN-ITLGQALVVIDEAYIEFSPEE 195
Query: 178 KSP----EGENIVKLRTFTKSYGLPGIRVGYIIGFRDAFRSVR-----MPWSIGSTGVAF 228
+ N+V LRT +K++ L GIR G+ + ++ +++ P SI + +A
Sbjct: 196 SMTNYLKDYPNLVVLRTLSKAFALAGIRCGFTLAKKEIIQTLSKVISPYPISIPVSDIAI 255
Query: 229 LEFLIEDNFEHLRKTMPL------IW---QEKERIEKALNVKSDANFFIKYVGDAKKAVE 279
+E ++ L K L IW Q K +S+AN+ + +K E
Sbjct: 256 RS--LEKDYVQLMKNRVLDSNNNRIWLINQLKNITCVETVFESNANYVLVKFSMFEKVFE 313
Query: 280 ELKKRGILVRDCT-SFGLPGYIRFSVRRAEENERLVQALKDLS 321
L +GI++R+ L IR S+ E+ RL++ LK S
Sbjct: 314 TLWNKGIILRNQNEKTNLKKCIRISMGTRSESLRLIKELKIFS 356
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.141 0.409
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 127057326
Number of Sequences: 2977
Number of extensions: 5475536
Number of successful extensions: 14558
Number of sequences better than 1.0e-10: 59
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 14422
Number of HSP's gapped (non-prelim): 59
length of query: 329
length of database: 189,106,746
effective HSP length: 55
effective length of query: 274
effective length of database: 156,189,961
effective search space: 42796049314
effective search space used: 42796049314
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)