BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0060 (PAB0060) DE:PURINE PHOSPHORIBOSYLTRANSFERASE related protein (153 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||A75197 purine phosphoribosyltransferase related protein PAB... 316 9e-86 pir||E71229 probable purine phosphoribosyltransferase - Pyrococc... 302 2e-81 gb|AAK42568.1| Purine phosphoribosyltransferase (gpT-2) [Sulfolo... 132 2e-30 pir||A72512 probable hypoxanthine phosphoribosyltransferase APE2... 126 1e-28 gi|11497855 xanthine-guanine phosphoribosyltransferase (gptA-1) ... 106 2e-22 pir||T36612 probable purine phosphoribosyltransferase - Streptom... 92 4e-18 dbj|BAA07148.1| (D37928) purine phosphoribosyltransferase [Therm... 91 7e-18 emb|CAC12472.1| (AL445067) purine phosphoribosyltransferase rela... 83 2e-15 gb|AAK42493.1| Purine phosphoribosyltransferase (gpT-1) [Sulfolo... 79 2e-14 pir||C72745 hypothetical protein APE0490 - Aeropyrum pernix (str... 76 2e-13 gb|AAG18909.1| (AE004993) purine phosphoribosyltransferase; GptA... 76 3e-13 pir||D75215 purine phosphoribosyltransferase PAB2405 - Pyrococcu... 74 8e-13 pir||H71451 hypothetical protein PH0271 - Pyrococcus horikoshii ... 73 1e-12 pir||G81028 conserved hypothetical protein NMB1912 [imported] - ... 69 4e-11 pir||G81972 hypothetical protein NMA0543 [imported] - Neisseria ... 69 4e-11 >pir||A75197 purine phosphoribosyltransferase related protein PAB0060 - Pyrococcus abyssi (strain Orsay) >gi|5457533|emb|CAB49024.1| (AJ248283) PURINE PHOSPHORIBOSYLTRANSFERASE related protein [Pyrococcus abyssi] Length = 153 Score = 316 bits (801), Expect = 9e-86 Identities = 153/153 (100%), Positives = 153/153 (100%) Query: 1 MDKVYLTWWQVDRAIFALAEKLREYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKF 60 MDKVYLTWWQVDRAIFALAEKLREYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKF Sbjct: 1 MDKVYLTWWQVDRAIFALAEKLREYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKF 60 Query: 61 YKGIDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLA 120 YKGIDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLA Sbjct: 61 YKGIDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLA 120 Query: 121 MKPWTSVVPDYYVFRTDKWIVFPWEEFPVIEKG 153 MKPWTSVVPDYYVFRTDKWIVFPWEEFPVIEKG Sbjct: 121 MKPWTSVVPDYYVFRTDKWIVFPWEEFPVIEKG 153 >pir||E71229 probable purine phosphoribosyltransferase - Pyrococcus horikoshii >gi|3256481|dbj|BAA29164.1| (AP000001) 153aa long hypothetical purine phosphoribosyltransferase [Pyrococcus horikoshii] Length = 153 Score = 302 bits (764), Expect = 2e-81 Identities = 143/152 (94%), Positives = 149/152 (97%) Query: 1 MDKVYLTWWQVDRAIFALAEKLREYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKF 60 MDKVYLTWWQVDRAIFALAEKLREYKPDVI+GVARGGLIPAVRLSHIL D+PLKVIDVKF Sbjct: 1 MDKVYLTWWQVDRAIFALAEKLREYKPDVIIGVARGGLIPAVRLSHILGDIPLKVIDVKF 60 Query: 61 YKGIDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLA 120 YKGIDER EKPVITIPIHGDLK K+VVIVDDVSDTGKTLEVVI+EVKKLGAKEIK+ACLA Sbjct: 61 YKGIDERGEKPVITIPIHGDLKDKRVVIVDDVSDTGKTLEVVIEEVKKLGAKEIKIACLA 120 Query: 121 MKPWTSVVPDYYVFRTDKWIVFPWEEFPVIEK 152 MKPWTSVVPDYYVFRT+KWIVFPWEEFPVIEK Sbjct: 121 MKPWTSVVPDYYVFRTEKWIVFPWEEFPVIEK 152 >gb|AAK42568.1| Purine phosphoribosyltransferase (gpT-2) [Sulfolobus solfataricus] Length = 179 Score = 132 bits (330), Expect = 2e-30 Identities = 59/148 (39%), Positives = 97/148 (64%), Gaps = 2/148 (1%) Query: 7 TWWQVDRAIFALAEKL--REYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKGI 64 +W +++ A+F++ E L Y PDV++ V GG+IPA LS +L+ ++ ID+KFY+ + Sbjct: 8 SWDEIEDAVFSIGEALVKSNYIPDVLIAVLTGGIIPAKLLSDLLDLKVIRYIDIKFYRSV 67 Query: 65 DERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLAMKPW 124 + KPVI L+GKKV++VDDV+DTG+TLE V + + ++ A L +KPW Sbjct: 68 GKTESKPVIRSVYTDSLEGKKVLVVDDVADTGETLEAVSNVITMFNPAKVMTAALYLKPW 127 Query: 125 TSVVPDYYVFRTDKWIVFPWEEFPVIEK 152 + +PD+Y + DKWI+FPW+++ V+ + Sbjct: 128 SKRIPDFYYKQIDKWIIFPWDKWDVVRE 155 >pir||A72512 probable hypoxanthine phosphoribosyltransferase APE2071 - Aeropyrum pernix (strain K1) >gi|5105769|dbj|BAA81081.1| (AP000063) 272aa long hypothetical hypoxanthine phosphoribosyltransferase [Aeropyrum pernix] Length = 272 Score = 126 bits (314), Expect = 1e-28 Identities = 60/154 (38%), Positives = 100/154 (63%), Gaps = 2/154 (1%) Query: 1 MDKVYLTWWQVDRAIFALAEKL--REYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDV 58 ++ ++L+W ++ A+ +A+K+ ++PDVIVG+ RGG++PA+ L+ L + V+++ Sbjct: 111 VELIHLSWRDIEDAVRDVADKIVGSGFEPDVIVGILRGGIVPALLLADALGVKNIGVMEI 170 Query: 59 KFYKGIDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVAC 118 K Y + R +P + P+ ++K + V++VDDVSD+G TL+ I+ V ++K A Sbjct: 171 KLYTSVGVRKPRPFLRQPLVIEVKDRNVLVVDDVSDSGLTLQHAIEAVDLYLPAQVKTAT 230 Query: 119 LAMKPWTSVVPDYYVFRTDKWIVFPWEEFPVIEK 152 L +KPWT++VPDYY DKWIVFPWE V E+ Sbjct: 231 LYIKPWTNLVPDYYSKSLDKWIVFPWERREVEEE 264 >gi|11497855 xanthine-guanine phosphoribosyltransferase (gptA-1) [Archaeoglobus fulgidus] >gi|7484010|pir||G69279 xanthine-guanine phosphoribosyltransferase (gptA-1) homolog - Archaeoglobus fulgidus >gi|2650402|gb|AAB90994.1| (AE001089) xanthine-guanine phosphoribosyltransferase (gptA-1) [Archaeoglobus fulgidus] Length = 194 Score = 106 bits (261), Expect = 2e-22 Identities = 57/145 (39%), Positives = 89/145 (61%), Gaps = 5/145 (3%) Query: 4 VYLTWWQVDRAIFALAEKLRE--YKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFY 61 V TW ++ + LA K+RE Y+PD +V +ARGG +PA + L+ L + + + Sbjct: 6 VLYTWDEIRKLCKELAMKVRESGYQPDAVVAIARGGWVPARIVCDYLDIRELYSVKTEHW 65 Query: 62 KGIDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLAM 121 + E+ E+ IT P++ D+ GKK++IVDDV+DTG T+ VV+D V + EI+VA + Sbjct: 66 D-VAEKREEAKITQPLNVDVSGKKILIVDDVADTGDTIRVVVDHVNQYRPAEIRVAVVDY 124 Query: 122 KPWTSVVPDYYVFRTD--KWIVFPW 144 K + VPDYY + + +WIV+PW Sbjct: 125 KTTSKFVPDYYAAKMEAWRWIVYPW 149 >pir||T36612 probable purine phosphoribosyltransferase - Streptomyces coelicolor >gi|5019327|emb|CAB44380.1| (AL078610) putative purine phosphoribosyltransferase [Streptomyces coelicolor A3(2)] Length = 165 Score = 91.7 bits (224), Expect = 4e-18 Identities = 54/149 (36%), Positives = 87/149 (58%), Gaps = 5/149 (3%) Query: 6 LTWWQVDRAIFALAEKLRE--YKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKG 63 LT+ Q A+ LA+ + + Y+PD+++ +ARGG+ A L++ L+ + +++V+FY G Sbjct: 8 LTYEQFGVAVRELAQAVADDGYEPDIVLSIARGGVFVAGGLAYALDCKNIHLVNVEFYTG 67 Query: 64 IDERAEKPVITIPIHG--DLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLAM 121 + + PV+ P+ D KKV+I DDV+DTGKTL++V D A E++ A + Sbjct: 68 VGTTLDMPVMLAPVPNVIDFSDKKVLITDDVADTGKTLKLVRDFCLDTVA-EVRSAVIYE 126 Query: 122 KPWTSVVPDYYVFRTDKWIVFPWEEFPVI 150 K + V +Y RTD WI FPW P + Sbjct: 127 KSHSLVQCEYVWKRTDDWINFPWSVQPPV 155 >dbj|BAA07148.1| (D37928) purine phosphoribosyltransferase [Thermus aquaticus] Length = 154 Score = 90.9 bits (222), Expect = 7e-18 Identities = 54/147 (36%), Positives = 81/147 (54%), Gaps = 4/147 (2%) Query: 1 MDKVYLTWWQVDRAIFALAEKLREYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKF 60 M++++L+W + R + LAE L D+++GVARGGLIP L+ L + V F Sbjct: 1 MERLHLSWEDLLRLVRRLAEALSGEPFDLVLGVARGGLIPTALLAQALGARNILTAAVMF 60 Query: 61 YKGIDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLA 120 Y+G + E + P L GK+V++VDDV D+G+T V V++ G + VA L Sbjct: 61 YEGEEALPEPVFLQFPPDVLLFGKRVLVVDDVWDSGRTAFAVKARVRRAGGVPV-VATLH 119 Query: 121 MKPWTSVV---PDYYVFRTDKWIVFPW 144 KP + V PD+Y T W+V+PW Sbjct: 120 FKPGRNRVPDRPDFYAEETAAWVVYPW 146 >emb|CAC12472.1| (AL445067) purine phosphoribosyltransferase related protein [Thermoplasma acidophilum] Length = 217 Score = 83.1 bits (202), Expect = 2e-15 Identities = 48/147 (32%), Positives = 82/147 (55%), Gaps = 5/147 (3%) Query: 6 LTWWQVDRAIFALAEKLR-EYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKGI 64 ++W +DR ++ K++ + D I+G+ARGGL+PA LS L L + + + Sbjct: 10 VSWADIDRWCGNISRKVQASFDVDTIIGIARGGLVPARILSDRLWVKDLLSVKTEHWGIT 69 Query: 65 DERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLAMKPW 124 + + V+ I+ DL GK V++VDD++DTG+++ + D VK L +E++ A + Sbjct: 70 ATKDGEAVLKTKINMDLSGKNVLVVDDITDTGESMSLAYDYVKSLKPRELRSATMLHISR 129 Query: 125 TSVVPDYY-VFRTDK---WIVFPWEEF 147 + VPDYY T+K W +FPW + Sbjct: 130 SKFVPDYYSELITEKNWAWFIFPWNVY 156 >gb|AAK42493.1| Purine phosphoribosyltransferase (gpT-1) [Sulfolobus solfataricus] Length = 210 Score = 79.2 bits (192), Expect = 2e-14 Identities = 46/145 (31%), Positives = 78/145 (53%), Gaps = 6/145 (4%) Query: 6 LTWWQVDRAIFALAEKLR--EYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKG 63 +TW ++ LAEK++ EY +VIV +ARGGL+PA ++ +L + I ++ + Sbjct: 9 VTWDEIVSLSTKLAEKIKADEYNVNVIVAIARGGLVPARLVADVLGVFDILSIKIEHWIE 68 Query: 64 IDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEV-KKLGAKEIKVACLA-M 121 + + P DL K V+I+DD++DTG ++E+ V + E+K A L + Sbjct: 69 TASHTPEAKVKYPFKVDLSDKNVLIIDDITDTGDSIELARKYVMENFRPTEVKTATLQYI 128 Query: 122 KPWTSVVPDYYV--FRTDKWIVFPW 144 KP ++PDYY + W ++PW Sbjct: 129 KPAAKIIPDYYAEEIVSWAWFMYPW 153 >pir||C72745 hypothetical protein APE0490 - Aeropyrum pernix (strain K1) >gi|5104139|dbj|BAA79455.1| (AP000059) 226aa long hypothetical protein [Aeropyrum pernix] Length = 226 Score = 76.1 bits (184), Expect = 2e-13 Identities = 50/146 (34%), Positives = 73/146 (49%), Gaps = 12/146 (8%) Query: 8 WWQVDRAIFALAEKLRE--YKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKGID 65 W + L+ +RE Y+PDV++ V+RGG +PA L L+ L I + + Sbjct: 8 WSDIVEWSLGLSNMIRESGYEPDVVIAVSRGGFVPARLLCDFLDVTNLLSIQSQHWVEAA 67 Query: 66 ERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEV-KKLGAKEIKVACLAMKPW 124 AEK ++ P DL G K ++VDD+ DTG TL + + + K+ E++VA L W Sbjct: 68 RMAEKAILKFPYRVDLSGLKALLVDDIVDTGDTLLLAKEFIEKEWKPGELRVAAL---QW 124 Query: 125 TSVV----PDYYVFRTDKWIVF--PW 144 S V PDYY +W F PW Sbjct: 125 ISSVAKFKPDYYYMEVREWAWFQYPW 150 >gb|AAG18909.1| (AE004993) purine phosphoribosyltransferase; GptA1 [Halobacterium sp. NRC-1] Length = 230 Score = 75.7 bits (183), Expect = 3e-13 Identities = 41/127 (32%), Positives = 71/127 (55%), Gaps = 3/127 (2%) Query: 21 KLREYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKGIDERAEKPVITIPI-HG 79 K +++PDV+V +ARGG L L L + ++ Y G E++ +P + P+ G Sbjct: 30 KAADFEPDVVVALARGGWFAGRCLCDFLGLNDLTSLKMEHYVGTAEKSAEPEVRYPMPEG 89 Query: 80 DLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLAMKPWTSVVPDYYVFRTDK- 138 ++ K V+I+DD++DTG ++E + V+ A ++ A L + ++ PDY R D+ Sbjct: 90 SVEDKDVLIIDDIADTGGSIEHAHEYVQDRDANAVRTATLQLLQTSAFEPDYVGERLDEW 149 Query: 139 -WIVFPW 144 WIV+PW Sbjct: 150 AWIVYPW 156 >pir||D75215 purine phosphoribosyltransferase PAB2405 - Pyrococcus abyssi (strain Orsay) >gi|5457680|emb|CAB49171.1| (AJ248283) purine phosphoribosyltransferase [Pyrococcus abyssi] Length = 215 Score = 74.1 bits (179), Expect = 8e-13 Identities = 48/141 (34%), Positives = 72/141 (51%), Gaps = 3/141 (2%) Query: 7 TWWQVDRAIFALAEKLRE--YKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKGI 64 +W ++ A A K+ E + PDV+VG+ARGG I A L L I V+ + Sbjct: 10 SWDDIEEWAKAGAWKVLESGWMPDVVVGLARGGWIAARLYCDYLGVKDLVSIKVEHWGIT 69 Query: 65 DERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLAMKPW 124 + + D +GKKV+IVDD++DTG+++ + + +K EI+ A L Sbjct: 70 ATPDGRARLKYGAQYDFEGKKVLIVDDITDTGESMSLAYEYMKSRNPAEIRTATLLNIKG 129 Query: 125 TSVVPDYYVFRTD-KWIVFPW 144 + VPDYY D WI+FPW Sbjct: 130 SKFVPDYYAKDIDWAWIIFPW 150 >pir||H71451 hypothetical protein PH0271 - Pyrococcus horikoshii >gi|3256660|dbj|BAA29343.1| (AP000001) 215aa long hypothetical protein [Pyrococcus horikoshii] Length = 215 Score = 73.4 bits (177), Expect = 1e-12 Identities = 43/121 (35%), Positives = 63/121 (51%), Gaps = 1/121 (0%) Query: 25 YKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKGIDERAEKPVITIPIHGDLKGK 84 + PDVIVG+ARGG I A L L + V+ + + + D +GK Sbjct: 30 WMPDVIVGLARGGWIAARLYCDYLGVKDLVSVKVEHWGITATPDGRARLKYGTQYDFEGK 89 Query: 85 KVVIVDDVSDTGKTLEVVIDEVKKLGAKEIKVACLAMKPWTSVVPDYYVFRTD-KWIVFP 143 KV+IVDD++DTG+++ + + +K EIK A L + +PDYY D W+VFP Sbjct: 90 KVLIVDDITDTGESMSLAYEYMKSRNPAEIKTATLLNIKGSKFIPDYYAKDIDWVWVVFP 149 Query: 144 W 144 W Sbjct: 150 W 150 >pir||G81028 conserved hypothetical protein NMB1912 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7227169|gb|AAF42242.1| (AE002540) conserved hypothetical protein [Neisseria meningitidis MC58] Length = 175 Score = 68.7 bits (165), Expect = 4e-11 Identities = 48/163 (29%), Positives = 82/163 (49%), Gaps = 15/163 (9%) Query: 3 KVYLTWWQVDRAIFALAEKLR--EYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKF 60 K++ T+ + R I ALAEK+R + K D ++ + GG IPA R+ ++P+ + + Sbjct: 4 KIWYTYDDIHRVIKALAEKIRNADIKYDAMIAIGGGGFIPA-RMLRCFLEIPIYAVTTAY 62 Query: 61 YKG-----IDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIK 115 Y + E +K P+ L+GK V++VD+V D+ T+E + E+ K I Sbjct: 63 YDSDNEGQVTEEVKKVQWLDPVPEALRGKNVLVVDEVDDSRVTMEFCLKELLKEDFGTIG 122 Query: 116 VACL--AMKPWTSVVPD---YY--VFRTDKWIVFPWEEFPVIE 151 VA L +K +P+ Y+ + D WI +PW+ + E Sbjct: 123 VAVLHEKIKAKAGKIPEGIPYFSGITVEDWWINYPWDALDIDE 165 >pir||G81972 hypothetical protein NMA0543 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379282|emb|CAB83836.1| (AL162753) hypothetical protein NMA0543 [Neisseria meningitidis Z2491] Length = 175 Score = 68.7 bits (165), Expect = 4e-11 Identities = 48/163 (29%), Positives = 82/163 (49%), Gaps = 15/163 (9%) Query: 3 KVYLTWWQVDRAIFALAEKLR--EYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKF 60 K++ T+ + R I ALAEK+R + K D ++ + GG IPA R+ ++P+ + + Sbjct: 4 KIWYTYDDIHRVIKALAEKIRNADIKYDAMIAIGGGGFIPA-RMLRCFLEIPIYAVTTAY 62 Query: 61 YKG-----IDERAEKPVITIPIHGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEIK 115 Y + E +K P+ L+GK V++VD+V D+ T+E + E+ K I Sbjct: 63 YDSDNEGQVTEEVKKVQWLDPVPEALRGKNVLVVDEVDDSRVTMEFCLTELLKEDFGTIG 122 Query: 116 VACL--AMKPWTSVVPD---YY--VFRTDKWIVFPWEEFPVIE 151 VA L +K +P+ Y+ + D WI +PW+ + E Sbjct: 123 VAVLHEKIKAKAGKIPEGIPYFSGITVEDWWINYPWDALDIDE 165 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.322 0.143 0.439 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 59320326 Number of Sequences: 2977 Number of extensions: 2401116 Number of successful extensions: 7931 Number of sequences better than 1.0e-10: 15 Number of HSP's better than 0.0 without gapping: 6 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 7907 Number of HSP's gapped (non-prelim): 15 length of query: 153 length of database: 189,106,746 effective HSP length: 49 effective length of query: 104 effective length of database: 159,780,883 effective search space: 16617211832 effective search space used: 16617211832 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.9 bits) S2: 162 (67.5 bits)