BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0066 (PAB0066) DE:fragment of ALANYL-TRNA SYNTHETASE
(213 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75198 alanine--tRNA ligase truncated homolog PAB0066 - Pyr... 449 e-125
pir||B71231 alanine--tRNA ligase truncated homolog PH0108 - Pyro... 437 e-122
pir||B75017 alanyl-tRNA synthetase (alas) PAB1245 - Pyrococcus a... 133 2e-30
sp|O58035|SYA_PYRHO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 127 8e-29
gb|AAK40671.1| Alanyl-tRNA synthetase (alaS) [Sulfolobus solfata... 127 1e-28
pir||G75027 alanyl-tRNA synthetase related protein PAB1190 - Pyr... 127 1e-28
sp|Q9Y9X3|SYA_AERPE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 123 2e-27
emb|CAC11271.1| (AL445063) alanyl-tRNA synthetase related protei... 122 4e-27
pir||A71213 alanine--tRNA ligase truncated homolog PH1969 - Pyro... 122 4e-27
gb|AAK40776.1| Alanyl-tRNA synthetase truncated homolog (alaS-li... 108 8e-23
sp|Q57984|SYA_METJA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 108 8e-23
emb|CAC11978.1| (AL445065) alanyl-tRNA synthetase related protei... 106 3e-22
gb|AAG20397.1| (AE005112) alanyl-tRNA synthetase; AlaS [Halobact... 102 4e-21
dbj|BAB06653.1| (AP001517) unknown conserved protein in others [... 101 1e-20
gi|11499836 alanyl-tRNA synthetase (alaS) [Archaeoglobus fulgidu... 101 1e-20
pir||A83382 hypothetical protein PA2106 [imported] - Pseudomonas... 95 8e-19
pir||C81396 alanine--tRNA ligase (EC 6.1.1.7) Cj0506 [imported] ... 92 7e-18
sp|O27718|SYA_METTH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 91 9e-18
sp|O67323|SYA_AQUAE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 88 1e-16
sp|Q9XDM3|SYA_AQUPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 82 6e-15
dbj|BAB04986.1| (AP001511) alanyl-tRNA synthetase [Bacillus halo... 82 6e-15
pir||C81804 alanine--tRNA ligase (EC 6.1.1.7) NMA1788 [imported]... 76 2e-13
pir||F81063 alanyl-tRNA synthetase NMB1595 [imported] - Neisseri... 75 9e-13
dbj|BAB10601.1| (AB005243) alanyl-tRNA synthetase [Arabidopsis t... 75 9e-13
sp|Q9X1B6|SYA_THEMA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 74 2e-12
gb|AAG23137.1|AF245445_1 (AF245445) alanyl-tRNA synthetase [Giar... 74 2e-12
sp|Q56273|SYA_THIFE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 73 3e-12
gb|AAF05594.1|AF188719_1 (AF188719) alanyl-tRNA synthetase [Giar... 73 4e-12
sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 72 5e-12
sp|O34526|SYA_BACSU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 72 5e-12
gb|AAF45874.1| (AE003427) CG10802 gene product [Drosophila melan... 71 8e-12
sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 71 1e-11
pir||G72685 probable alanyl-tRNA synthetase APE0903 - Aeropyrum ... 71 1e-11
gb|AAG23689.1|AF297520_1 (AF297520) alanyl-tRNA synthase [Haemop... 70 2e-11
>pir||A75198 alanine--tRNA ligase truncated homolog PAB0066 - Pyrococcus abyssi
(strain Orsay) >gi|5457541|emb|CAB49032.1| (AJ248283)
fragment of ALANYL-TRNA SYNTHETASE [Pyrococcus abyssi]
Length = 213
Score = 449 bits (1143), Expect = e-125
Identities = 213/213 (100%), Positives = 213/213 (100%)
Query: 1 MTRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDE 60
MTRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDE
Sbjct: 1 MTRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDE 60
Query: 61 EGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGS 120
EGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGS
Sbjct: 61 EGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGS 120
Query: 121 GMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEGETRYTQIRDFEVIPCG 180
GMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEGETRYTQIRDFEVIPCG
Sbjct: 121 GMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEGETRYTQIRDFEVIPCG 180
Query: 181 GTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWLE 213
GTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWLE
Sbjct: 181 GTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWLE 213
>pir||B71231 alanine--tRNA ligase truncated homolog PH0108 - Pyrococcus
horikoshii >gi|3256494|dbj|BAA29177.1| (AP000001) 216aa
long hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 216
Score = 437 bits (1111), Expect = e-122
Identities = 204/213 (95%), Positives = 210/213 (97%)
Query: 1 MTRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDE 60
MTRKLYYEDAYLKEAK +V+EI+DNA+LLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDE
Sbjct: 4 MTRKLYYEDAYLKEAKGRVLEIRDNAILLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDE 63
Query: 61 EGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGS 120
EGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEG W+LVGS
Sbjct: 64 EGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGNWQLVGS 123
Query: 121 GMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEGETRYTQIRDFEVIPCG 180
GMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEG+ RYTQIRDFEVIPCG
Sbjct: 124 GMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEGDRRYTQIRDFEVIPCG 183
Query: 181 GTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWLE 213
GTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWLE
Sbjct: 184 GTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWLE 216
>pir||B75017 alanyl-tRNA synthetase (alas) PAB1245 - Pyrococcus abyssi (strain
Orsay) >gi|5459090|emb|CAB50576.1| (AJ248288)
alanyl-tRNA synthetase (alaS) [Pyrococcus abyssi]
Length = 914
Score = 133 bits (331), Expect = 2e-30
Identities = 87/232 (37%), Positives = 125/232 (53%), Gaps = 26/232 (11%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGT--INGVEVLDVYKD 59
TR LYYED ++KE +A+V+ + + ++LDQT FYP GGGQP+D G +NG EV
Sbjct: 516 TRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQ 575
Query: 60 EEGNV-WHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELV 118
+ G V H V+ P FK G EV +IDWD R + MR HTG H+L L VLG+ W+
Sbjct: 576 KVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQ-A 634
Query: 119 GSGMSVEKGRYDIAYPENLNKYK-EQIISLFNKYVDEGGEVKIWW----EGETRY----- 168
GS ++ + R DI++ + ++ + +I L N+ V E +V W E E RY
Sbjct: 635 GSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLY 694
Query: 169 ------------TQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 208
+I D++V CGGTH+ +G IK L+ I G +R+
Sbjct: 695 QGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERI 746
>sp|O58035|SYA_PYRHO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437626|pir||C71455 alanine--tRNA ligase (EC
6.1.1.7) - Pyrococcus horikoshii
>gi|3256687|dbj|BAA29370.1| (AP000001) 915aa long
hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 915
Score = 127 bits (317), Expect = 8e-29
Identities = 85/234 (36%), Positives = 124/234 (52%), Gaps = 30/234 (12%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGT--INGVEVLDVYKD 59
TR+LYYED ++KE AKV+ + + ++LD T FYP GGGQP+D G +NG EV
Sbjct: 516 TRRLYYEDPFMKEFDAKVLRVIKDWVILDATAFYPEGGGQPYDTGVLIVNGREVKVTNVQ 575
Query: 60 EEGNV-WHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELV 118
+ G V H V++P FK G V KIDW R + MR HTG H+L L VLG W+
Sbjct: 576 KVGKVIIHKVEDPGAFKEGMIVHGKIDWKRRIQHMRHHTGTHVLMGALVRVLGRHVWQ-A 634
Query: 119 GSGMSVEKGRYDIAYPENLNKYK-EQIISLFNKYVDEGGEVKIWWE-------------- 163
GS ++ + R DI++ + +++ + ++I L N+ V E + K+ WE
Sbjct: 635 GSQLTTDWARLDISHYKRISEEELKEIEMLANRIVME--DRKVTWEWLPRTTAEQKYGFR 692
Query: 164 ---------GETRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 208
E R +I D++V CGGTH+ +G IK L+ I G +R+
Sbjct: 693 LYQGGVVPGREIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERI 746
>gb|AAK40671.1| Alanyl-tRNA synthetase (alaS) [Sulfolobus solfataricus]
Length = 900
Score = 127 bits (316), Expect = 1e-28
Identities = 82/236 (34%), Positives = 123/236 (51%), Gaps = 29/236 (12%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTI------NGVEVLD 55
T KLYY+D Y++ + KV+ I N L+LD+T FYP GGGQ D G I EV+D
Sbjct: 504 TEKLYYKDQYMRSFEGKVLGIYKNYLILDKTTFYPEGGGQLGDTGLIIDEKSSKRYEVVD 563
Query: 56 VYKDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKW 115
K + + + +EP KVGD V +I+W+ RY+LMR HT H++ +VLG+ W
Sbjct: 564 TQKVNDVIIHVLKEEPSTIKVGDNVRGEINWERRYRLMRHHTVTHVILAAAKKVLGDHIW 623
Query: 116 ELVGSGMSVEKGRYDIAYPENLNKYKEQIISLF-NKYVDEGGEVKIW----WEGETRY-- 168
+ G+ + EKGR DI + + L + + ++I + N + + VK E E +Y
Sbjct: 624 Q-AGAEKTPEKGRLDITHHKALTEEEVKLIENYANSVISDRRPVKPLEMNRMEAEMKYGV 682
Query: 169 ---------------TQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
+I+D+++ CGGTHV + EIG +K + I G RLE
Sbjct: 683 SIYEGGVPNSATIRLLEIKDWDIESCGGTHVSNTSEIGAVKIINVERIQDGIIRLE 738
>pir||G75027 alanyl-tRNA synthetase related protein PAB1190 - Pyrococcus abyssi
(strain Orsay) >gi|5459175|emb|CAB50661.1| (AJ248288)
alanyl-tRNA synthetase related protein (fragment)
[Pyrococcus abyssi]
Length = 405
Score = 127 bits (316), Expect = 1e-28
Identities = 85/241 (35%), Positives = 127/241 (52%), Gaps = 40/241 (16%)
Query: 1 MTRKLYYEDAYLKEAKAKVVEIKDNA----LLLDQTIFYPTGGGQPHDRGTINGVEVLDV 56
M RKLYY D YLK AKAK+ ++ + L +TIFYP GGGQP D+G I G +
Sbjct: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
Query: 57 YKD---EEGNVWHVVKEPEKF-KVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLN----- 107
+D +G +WHV K + +VG+EVEL++DW++RY M++HTG H+L VL
Sbjct: 61 VEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDL 120
Query: 108 --------------EVLGEGKWELVGSGMSVEKGRYDI-AYPENLNKYK---EQIISLFN 149
EV GE WE++ +E + I P + +Y+ + ++
Sbjct: 121 DTSGFNIFGDYAKIEVNGELNWEMIEEA-ELEANKVIIDDLPVRVEEYEVLPKGVVEKLR 179
Query: 150 KYVDE-GGEVKIWWEGETRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 208
KY+ G+++I GE +F++ PCGGTHVK +E+G IK L+ + R+
Sbjct: 180 KYIPNIKGKIRIVRIGE-------NFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRI 232
Query: 209 E 209
E
Sbjct: 233 E 233
>sp|Q9Y9X3|SYA_AERPE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437623|pir||A72524 probable alanyl-tRNA synthetase
APE2166 - Aeropyrum pernix (strain K1)
>gi|5105865|dbj|BAA81177.1| (AP000063) 900aa long
hypothetical alanyl-tRNA synthetase [Aeropyrum pernix]
Length = 900
Score = 123 bits (306), Expect = 2e-27
Identities = 82/236 (34%), Positives = 119/236 (49%), Gaps = 32/236 (13%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTI----NGVEVLDVY 57
TR++++ED Y K KA+V+ +K L+ D TIFYPTGGGQ HD G I ++DV
Sbjct: 490 TRRVFHEDPYAKAWKARVLGVKGRYLVADSTIFYPTGGGQIHDTGVIRVNNQQYRIIDVQ 549
Query: 58 KDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWEL 117
K + V HV + + GDEV ++IDW+ RY +MR HT H+L VLG W+
Sbjct: 550 KVGDAIV-HVAEREIAAEPGDEVWMEIDWERRYSIMRHHTVTHVLIAAARRVLGRHAWQ- 607
Query: 118 VGSGMSVEKGRYDIAYPENLNKYK-EQIISLFNKYVDEGGEVKIW--------------- 161
G+ + EKGR DI + L + E++ ++ N+ + E ++W
Sbjct: 608 AGAEKTEEKGRLDITHHRPLTRDDIEKLENVVNQVIRE--RRRVWEDMVDKNEAEEKYGF 665
Query: 162 --------WEGETRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
E R + D++V C GTHV++ EIG K + S I G RLE
Sbjct: 666 TIYQGGVPMEKRLRLVFVEDWDVEACFGTHVRNTGEIGGFKIISYSRIQDGVVRLE 721
>emb|CAC11271.1| (AL445063) alanyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 245
Score = 122 bits (303), Expect = 4e-27
Identities = 77/242 (31%), Positives = 126/242 (51%), Gaps = 34/242 (14%)
Query: 1 MTRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTI----NGVEVLDV 56
+T KLYY+D Y+KE +A+VV + N ++LD+T FYPTGGGQP+D G I V+DV
Sbjct: 5 VTEKLYYDDMYMKEFQAEVVSVDSNGIVLDRTAFYPTGGGQPNDTGIIVNDDKTYRVVDV 64
Query: 57 YKDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWE 116
K + +V H+++ + K GD + KIDW+ RY MR HT +H+L+ +++ +
Sbjct: 65 QKHGD-DVVHILESVDGLKAGDRIYGKIDWERRYAHMRYHTAIHILDGIVS-AKHNSEAL 122
Query: 117 LVGSGMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEGETRYTQIRD--- 173
L G + ++ R D+ ++ +QII N+++ EG +++ E +R ++
Sbjct: 123 LTGGQIYEDRSRIDMNIENFTKEFVDQIIQEANEFISEGH--RVYAENISREEAMKRPNL 180
Query: 174 ---------FEVIPC--------------GGTHVKDIKEIGHIKKLKRSSIGRGKQRLEM 210
E +P GGTHV + +E+G I K + GR +R+E
Sbjct: 181 ARTEPGRKLIESLPVVRIIVIEGLDEQSDGGTHVANTREVGKIVLRKIENKGRKNKRIEF 240
Query: 211 WL 212
L
Sbjct: 241 EL 242
>pir||A71213 alanine--tRNA ligase truncated homolog PH1969 - Pyrococcus
horikoshii >gi|3258413|dbj|BAA31096.1| (AP000007) 404aa
long hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 404
Score = 122 bits (303), Expect = 4e-27
Identities = 81/240 (33%), Positives = 124/240 (50%), Gaps = 39/240 (16%)
Query: 1 MTRKLYYEDAYLKEAKAKVVEIKDNA----LLLDQTIFYPTGGGQPHDRGTINGVEVLDV 56
M ++YY+D YL+E AK+V+++ ++LD+TIFYP GGGQP DRG I G + +
Sbjct: 1 MVERVYYKDPYLREIDAKIVDVRKEKDRVEVVLDRTIFYPEGGGQPGDRGVIKGNDFEIM 60
Query: 57 YKD---EEGNVWHVVK-EPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLN----- 107
+D + G ++H+ K E K G++V+L +DW++RY M++HTG H+L VL
Sbjct: 61 VEDTIEKNGEIFHIGKLRGEIPKEGEKVKLYLDWEWRYGNMQMHTGQHILSAVLKKLYDL 120
Query: 108 --------------EVLGEGKWELVGSGMSVEKGRYDI----AYPENLNKYKEQIISLFN 149
EV GE W+++ +E + I E +K E+I
Sbjct: 121 DTTGFNIFRDYAKIEVNGEVNWDMI-ERAELEVNKIIINDLPVVIEEYDKLPEEIALKLR 179
Query: 150 KYVDEGGEVKIWWEGETRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
K V + E + R +I D +V PCGGTHVK +E+G IK L+ + R+E
Sbjct: 180 KNVTKVKE-------KIRIVKIGDVDVTPCGGTHVKSTREVGIIKVLRFYKKSKNLWRIE 232
>gb|AAK40776.1| Alanyl-tRNA synthetase truncated homolog (alaS-like1) [Sulfolobus
solfataricus]
Length = 236
Score = 108 bits (266), Expect = 8e-23
Identities = 71/235 (30%), Positives = 119/235 (50%), Gaps = 32/235 (13%)
Query: 1 MTRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTI-----NGVEVLD 55
MT +LY +D+Y+KE + +VV I+ N ++LD+T FYP GGG +D G + + V +
Sbjct: 1 MTEELYLKDSYIKEFEGRVVRIEGNYVILDKTAFYPGGGGLDNDTGFLVNEKGERISVTE 60
Query: 56 VYKDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKW 115
V + E G + H + + V ++V IDWD RY++MR+HT H++ + G
Sbjct: 61 VKRGENGEILHKIDQNGSLNVNEKVIGTIDWDRRYRMMRLHTASHIVAALAYRKFGA--- 117
Query: 116 ELVGSGMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKIWWEGET--------- 166
+ G +S E+ + D EN + E +I+ N+ + + E+KI++
Sbjct: 118 LITGGHISPEQAKDDFNV-ENKDTLIE-LINEANEIIKKDIELKIYFLPREEALMIPAIV 175
Query: 167 -------------RYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 208
R +I ++ GG HVK+ KEIG I LK + G+G++R+
Sbjct: 176 KLAGRNPPQIPIWRIVEIPGIDIQADGGPHVKNTKEIGEIVLLKVENKGKGRKRV 230
>sp|Q57984|SYA_METJA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|2118343|pir||D64370 alanine--tRNA ligase (EC
6.1.1.7) - Methanococcus jannaschii
>gi|1591270|gb|AAB98556.1| (U67505) alanyl-tRNA
synthetase (alaS) [Methanococcus jannaschii]
Length = 892
Score = 108 bits (266), Expect = 8e-23
Identities = 79/239 (33%), Positives = 115/239 (48%), Gaps = 34/239 (14%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTI----NGVEVLDVY 57
T L+YE +KE +AK++ I D+ ++LD+T FYP GGGQ D G I V+DV
Sbjct: 492 TELLFYEYPKMKEFEAKILRIVDDYVILDRTAFYPEGGGQKADTGYIIKGDKKFRVVDVQ 551
Query: 58 KDEEGNVWHVVKE-PEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWE 116
K E V+H ++ ++ K GD V+ IDW R LMR HT H++ +VLG W+
Sbjct: 552 K-ENNIVYHKIENLNDELKEGDIVKGVIDWKRRLSLMRNHTATHIINAAAQKVLGRHVWQ 610
Query: 117 LVGSGMSVEKGRYDIAYPEN-----------------LNKYKEQIISLFNKYVDEGGEVK 159
GS + V+K R DI + + LN Y + I + +E +
Sbjct: 611 -AGSDVDVDKARLDITHYKRISREELKDIERVANEIVLNNYNIKSIFMDRNEAEEKFGFR 669
Query: 160 IWWEGET-----RYTQIRD-----FEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 208
I+ G R I D +V CGGTH ++ E+G IK +K + G +RL
Sbjct: 670 IYQGGVVPGNVLRIVIIEDENGNIVDVQACGGTHCQNTGEVGFIKIIKTERVQDGVERL 728
>emb|CAC11978.1| (AL445065) alanyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 871
Score = 106 bits (261), Expect = 3e-22
Identities = 80/241 (33%), Positives = 112/241 (46%), Gaps = 46/241 (19%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDEE 61
TR LYY+D +++E V+ K N ++LD+T FYP GGGQP D G YK +
Sbjct: 495 TRTLYYDDPFMREFTGLVLFSKGNEIILDKTAFYPEGGGQPWDLGYFE-------YKGKR 547
Query: 62 GNVWHVVKEPE--------KFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEG 113
NV V K + + G V IDW+ R +LM HT HLL VL EVLGE
Sbjct: 548 INVVAVRKYGKTIVHTLDGEIPQGVRVHGVIDWERRSRLMVHHTSTHLLLGVLREVLGEH 607
Query: 114 KWELVGSGMSVEKGRYDIAY-----PENLNKYKEQIISLFNKYVDEGGEVKI----WWEG 164
W+ G VE+ R DI + E + K +E++ L + EG EV + W+
Sbjct: 608 VWQ-NGVQKDVEESRLDITHYRKIDEETIRKIEERVFDL----IREGREVSVRNLDWYSA 662
Query: 165 ETRY-----------------TQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQR 207
+Y +I+ + CGGTH+K+I IG +K K +I R
Sbjct: 663 IDKYGFRLFEGGVPLTPKIRVVEIQGVDAEGCGGTHLKNISSIGVLKIRKVEAIQENIYR 722
Query: 208 L 208
+
Sbjct: 723 I 723
>gb|AAG20397.1| (AE005112) alanyl-tRNA synthetase; AlaS [Halobacterium sp. NRC-1]
Length = 929
Score = 102 bits (251), Expect = 4e-21
Identities = 81/242 (33%), Positives = 120/242 (49%), Gaps = 40/242 (16%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNA---------LLLDQTIFYPTGGGQPHDRGTING-- 50
T LYY+DAY E +A V+++ + ++LDQT+FYP GGGQP D G + G
Sbjct: 515 TETLYYDDAYGSEFEAVVLDVFEREGEDGDGAFDVVLDQTMFYPEGGGQPADTGVLTGDD 574
Query: 51 --VEVLDVYKDEEGNVWH-VVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLN 107
V+V+DV ++ +G V H P K G+ V +ID + R +LM HT H++ +
Sbjct: 575 HTVDVIDV-QERDGVVLHRTTDNPGK---GEFVRGQIDTERRRRLMAHHTATHIVVYAAR 630
Query: 108 EVLGEGKWELVGSGMSVEKGRYDIAYPENLNKYK-EQIISLFNKYVDEGGEVKIWW---- 162
+VLGE + G+ V+ R D+ + E +++ ++I + N+ V V+ W
Sbjct: 631 QVLGEHVRQ-AGAQKGVDSSRIDVTHYERVDRETVKEIERVANEIVRANTSVQCEWPDRH 689
Query: 163 EGETRY------------TQIR----DFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQ 206
E E Y QIR D +V CGGTHV EIG IK L + G +
Sbjct: 690 EAEAEYGFDLYQGGIPAGEQIRLVHVDDDVQACGGTHVARTGEIGSIKILNAERVQDGVE 749
Query: 207 RL 208
RL
Sbjct: 750 RL 751
>dbj|BAB06653.1| (AP001517) unknown conserved protein in others [Bacillus
halodurans]
Length = 242
Score = 101 bits (248), Expect = 1e-20
Identities = 73/239 (30%), Positives = 123/239 (50%), Gaps = 32/239 (13%)
Query: 1 MTRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTI--NG--VEVLDV 56
M+++LY ED+Y ++ + V + + ++L++TIF+P GGGQP+D G + NG +V++V
Sbjct: 1 MSKELYLEDSYRQDYTSNVKLLNKDKVILEETIFHPNGGGQPNDEGWLYQNGKAYKVINV 60
Query: 57 YKDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWE 116
K+ E + H +++ + + DEV +KI+W RY M+ HT LHL+ L G
Sbjct: 61 RKEGE-EIIHYLEDADDLE-EDEVRMKINWSRRYNFMKYHTLLHLVAGHLYHEYGA---L 115
Query: 117 LVGSGMSVEKGRYDIAY-PENLNKYKEQIISLFNKYVDEGGEVKI---WWEGET------ 166
+G+ + + R DI + L+ ++ N+ ++EG ++ I + E+
Sbjct: 116 AIGNQIFENRARLDIDFRGGELDVDFHRVEEELNRLINEGRKMNIRNVERDSESISEKIR 175
Query: 167 -------------RYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWL 212
R I + + PC GTHV +I EIG K S G+GK+RLE L
Sbjct: 176 TVINLIPASVKNIRLVAIENMDEQPCSGTHVNNINEIGPFKISGNKSKGKGKRRLEFQL 234
>gi|11499836 alanyl-tRNA synthetase (alaS) [Archaeoglobus fulgidus]
>gi|3334348|sp|O28029|SYA_ARCFU ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|7437618|pir||G69531
alanyl-tRNA synthetase (alaS) homolog - Archaeoglobus
fulgidus >gi|2648270|gb|AAB89002.1| (AE000949)
alanyl-tRNA synthetase (alaS) [Archaeoglobus fulgidus]
Length = 906
Score = 101 bits (248), Expect = 1e-20
Identities = 79/234 (33%), Positives = 123/234 (51%), Gaps = 30/234 (12%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTI--NG--VEVLDVY 57
T KLYY+D L E +A+V+ ++ + ++L+++ FYP GGQ +D G + NG EV+DV
Sbjct: 504 TEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVL 563
Query: 58 KDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWEL 117
+ +G V HVVK K +VG +V+ ID D R++ MR H+ H+L + L +VLG W+
Sbjct: 564 -EADGVVLHVVK-GAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQ- 620
Query: 118 VGSGMSVEKGRYDIAYPENLNKYK-EQIISLFNKYVDEGGEVKIWW----EGETRY---- 168
G+ K R D+ + ++ + ++I L N+ + +K W E E ++
Sbjct: 621 AGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRL 680
Query: 169 -------------TQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
Q+ D +V CGGTH + EIG +K LK SI G R E
Sbjct: 681 YQGGVPPGRKIRVVQVGD-DVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFE 733
>pir||A83382 hypothetical protein PA2106 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948120|gb|AAG05494.1|AE004638_4
(AE004638) hypothetical protein [Pseudomonas aeruginosa]
Length = 244
Score = 94.8 bits (232), Expect = 8e-19
Identities = 69/239 (28%), Positives = 109/239 (44%), Gaps = 49/239 (20%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTI-----NGVEVLDV 56
T L+ +D+Y +E A++ ++ ++ LLLDQT+FYP GGGQ D G + + + D
Sbjct: 4 TASLFLQDSYREECLARITDVVEDGLLLDQTVFYPQGGGQAGDSGWLTLADGTRLRIADT 63
Query: 57 YKDEEGN-----VWHVVKEPE-----KFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVL 106
K E + H+ E + K G+ V +IDW RY+ MR+HT H+L VL
Sbjct: 64 RKGTEAGAGRDAILHIPAEGQATVLRAMKPGEVVLAQIDWVRRYRHMRLHTAAHMLCAVL 123
Query: 107 NEVLGEGKWELVGSGMSVEKGRYDIAYPENLNKYKEQIISLFNKYVDEGGEVKI------ 160
+ + G ++ E R D E L+ +E I S V+ V I
Sbjct: 124 -------PYPVNGCSITDEHARLDFVTSEPLS--REAIDSALAAMVEAAHPVSIDTMSDD 174
Query: 161 -----------------WWEGETRYTQIRDFEVIPCGGTHVKDIKEIG--HIKKLKRSS 200
G+ R I+D ++ PCGGTHV + +E+G + K+++ S
Sbjct: 175 ALRARPDLVRTMSVQPPMGAGQVRLVSIKDTDLQPCGGTHVANTEEVGVVRVSKMEKKS 233
>pir||C81396 alanine--tRNA ligase (EC 6.1.1.7) Cj0506 [imported] - Campylobacter
jejuni (strain NCTC 11168) >gi|6967975|emb|CAB75143.1|
(AL139075) alanyl-tRNA synthetase [Campylobacter jejuni]
Length = 842
Score = 91.7 bits (224), Expect = 7e-18
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 24/221 (10%)
Query: 10 AYLKEAKAKVVEIKDNA-LLLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDEEGNVWHVV 68
A L E +V +KD ++L+ T FY T GGQ D G I EVLD K N+ +
Sbjct: 463 ALLDEDFKEVSTLKDAGWVMLENTPFYATSGGQSADSGFIAKREVLDTQKFFNLNL-SFI 521
Query: 69 KEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKGR 128
K E+ KV D V +ID + R ++ R H+ HLL H L E+LG + GS + K R
Sbjct: 522 KAGEELKVNDIVHARIDTEKREQIARHHSATHLLHHALREILGSHVSQ-AGSLVESNKLR 580
Query: 129 YDIAYPENLNKYK-EQIISLFNKYV----------------DEGGEVKIW---WEGETRY 168
+D + + LNK + E I NK + + G + ++ ++G R
Sbjct: 581 FDFTHHKALNKEELESIEKRVNKMIINSSEAILENMPLEEAKKSGAIALFNEKYQGNVRV 640
Query: 169 TQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
+ + + + CGGTHVK+ +IG +K S + G +R+E
Sbjct: 641 LTLGESKEL-CGGTHVKNTAQIGSFYIVKESGVSAGVRRIE 680
>sp|O27718|SYA_METTH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437627|pir||A69092 alanine--tRNA ligase (EC
6.1.1.7) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622813|gb|AAB86155.1| (AE000926)
alanyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 898
Score = 91.3 bits (223), Expect = 9e-18
Identities = 68/233 (29%), Positives = 109/233 (46%), Gaps = 26/233 (11%)
Query: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRG--TINGVEVLDVYKD 59
T L+Y++ E +A+V+ I +N L+LD+T+FYP GGGQP D G T G + + +
Sbjct: 492 TELLFYDEPDDLEFQAEVIGIHENGLILDRTLFYPEGGGQPSDTGYITAEGCRLRIKHAE 551
Query: 60 EEGN-VWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELV 118
+ G V H + + G + ID D R +L R HT HL+ +VLG+ W+
Sbjct: 552 KIGAVVVHRTDDEICIEPGTTIRGFIDSDRRLQLTRNHTATHLIVSAARKVLGDHIWQ-A 610
Query: 119 GSGMSVEKGRYDIAYPENLN-KYKEQIISLFNKYVDEGGEVKIWW--------------- 162
G+ V+ R D+++ + + ++I L N+YV +K+ W
Sbjct: 611 GAQKGVKSSRLDLSHYRRITLEELQEIERLANEYVMMNVPLKVRWMDRDLAERKYGFILY 670
Query: 163 ------EGETRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
R +I +V C GTHV +IG I+ + I G +R+E
Sbjct: 671 QGGVVPGSRIRVVEIPGVDVQACAGTHVHRTGDIGLIRINRTERIQDGVERIE 723
>sp|O67323|SYA_AQUAE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437619|pir||H70411 alanine--tRNA ligase (EC
6.1.1.7) - Aquifex aeolicus >gi|2983727|gb|AAC07289.1|
(AE000733) alanyl-tRNA synthetase [Aquifex aeolicus]
Length = 867
Score = 87.8 bits (214), Expect = 1e-16
Identities = 69/217 (31%), Positives = 107/217 (48%), Gaps = 26/217 (11%)
Query: 17 AKVVEIKDNALLLDQTIFYPTGGGQPHDRGTINGVEVL----DVYKDEEGNVWHVVKEPE 72
+++ E ++ ++L +T FYP GGGQ D G I + L D K EG + H+ K +
Sbjct: 475 SELKEGEEGEVVLKETPFYPEGGGQIGDAGIIESDKALFKVEDTQKPTEGIIVHIGKVLK 534
Query: 73 -KFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKGRYDI 131
KVGD V ++D + R+ +MR HT HLL L VLGE + GS ++ + R+D
Sbjct: 535 GTLKVGDTVHARVDKERRWDIMRNHTATHLLHAALRNVLGEHVRQ-AGSLVADKYLRFDF 593
Query: 132 AY-----PENLNKYKEQI---------ISLFNKYVDEG---GEVKIWWE--GE-TRYTQI 171
+ E L + +E + +++ DE G + I+ E GE R
Sbjct: 594 THFSALTEEELKRVEELVNEKIRENLPVNVMEMAYDEALKTGAIAIFEEKYGERVRVISC 653
Query: 172 RDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 208
+F CGGTHV +IG+ K + SS+G G +R+
Sbjct: 654 GEFSKELCGGTHVSATGDIGYFKIISESSVGAGVRRI 690
>sp|Q9XDM3|SYA_AQUPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|4587716|gb|AAD25871.1|AF027500_1 (AF027500)
alanyl-tRNA synthetase; alanine-tRNA ligase [Aquifex
pyrophilus]
Length = 871
Score = 81.9 bits (199), Expect = 6e-15
Identities = 68/220 (30%), Positives = 109/220 (48%), Gaps = 26/220 (11%)
Query: 14 EAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTIN---GV-EVLDVYKDEEGNVWHVVK 69
E +++ E ++ ++L +T FYP GGGQ D G I G+ +V D + EG + H+ K
Sbjct: 472 EIVSEIKEGEEGEIILRETPFYPEGGGQIGDSGIIETDKGIFKVEDTQRPTEGIIVHIGK 531
Query: 70 EPE-KFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKGR 128
+ K V D V ++D + R+ +MR HT HLL L +LGE + GS ++ + R
Sbjct: 532 LLKGKISVKDIVHARVDKERRWDIMRNHTATHLLHAALRNLLGEHVRQ-AGSLVADKYLR 590
Query: 129 YDIAYPENLNKYK-EQIISLFNKYVDEG----------------GEVKIWWE--GE-TRY 168
+D + L + + ++I L N+ + E G + I+ E GE R
Sbjct: 591 FDFTHFSPLTEEEIKRIEELVNEKIRENLPVSVMEMAYQEALQTGAIAIFEEKYGERVRV 650
Query: 169 TQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 208
+F CGGTHV +IG+ K + SS+G G +R+
Sbjct: 651 ISCGEFSKELCGGTHVSATGDIGYFKIISESSVGAGVRRI 690
>dbj|BAB04986.1| (AP001511) alanyl-tRNA synthetase [Bacillus halodurans]
Length = 879
Score = 81.9 bits (199), Expect = 6e-15
Identities = 65/208 (31%), Positives = 104/208 (49%), Gaps = 26/208 (12%)
Query: 27 LLLDQTIFYPTGGGQPHDRGTINGVE----VLDVYKDEEGNVWHVVKEPE-KFKVGDEVE 81
++L +T FY GGQ D+G I G V DV K G H V E +V D+V+
Sbjct: 492 VILKETPFYAESGGQVADKGIIRGANGFAVVSDVQKAPNGQHLHTVIVKEGTLQVNDQVQ 551
Query: 82 LKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKGRYDIA-YPENLNKY 140
++ R +++ HT HLL L +VLGE + GS +S E+ R+D + + + ++
Sbjct: 552 AIVEETERSGIVKNHTATHLLHRALKDVLGEHVNQ-AGSLVSEERLRFDFSHFGQVTDEE 610
Query: 141 KEQI-------------ISLFNKYVDEG---GEVKIWWE--GE-TRYTQIRDFEVIPCGG 181
KE+I +++ K +DE G + ++ E G+ R ++ D+ + CGG
Sbjct: 611 KEKIERIVNEKIWQAIKVNISTKTLDEAKAIGAMALFGEKYGDIVRVVEVGDYSIELCGG 670
Query: 182 THVKDIKEIGHIKKLKRSSIGRGKQRLE 209
HV + EIG K + S IG G +R+E
Sbjct: 671 CHVTNTSEIGLFKIVSESGIGAGVRRIE 698
>pir||C81804 alanine--tRNA ligase (EC 6.1.1.7) NMA1788 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380429|emb|CAB85015.1| (AL162757) alanyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 874
Score = 76.5 bits (185), Expect = 2e-13
Identities = 63/209 (30%), Positives = 96/209 (45%), Gaps = 26/209 (12%)
Query: 26 ALLLDQTIFYPTGGGQPHDRGTI----NGVEVLDVYKDEEGNVWHV-VKEPEKFKVGDEV 80
A+++D T FY GGQ D G I N EV D K + V+ + KVGD V
Sbjct: 487 AVVIDFTPFYAESGGQVGDVGYIFSSENRFEVRDTQKIKAAVFGQFGVQTSGRLKVGDSV 546
Query: 81 ELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKGRYDIAYPENL--- 137
K+D + R MR H+ HL+ L +VLG G E GS ++ E R+DI++P+ +
Sbjct: 547 TAKVDDEIRNANMRNHSATHLMHKALRDVLG-GHVEQKGSLVTAESTRFDISHPQAVTAE 605
Query: 138 ------NKYKEQIIS--------LFNKYVDEGGEVKIWWE---GETRYTQIRDFEVIPCG 180
+ E +++ + + + G + ++ E E R Q+ F CG
Sbjct: 606 EIAEVERRVNEAVLANVAVNAAIMSMEDAQKTGAMMLFGEKYGEEVRVLQMGGFSTELCG 665
Query: 181 GTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
GTHV +IG K + I G +R+E
Sbjct: 666 GTHVSRTGDIGLFKIISEGGIAAGVRRIE 694
>pir||F81063 alanyl-tRNA synthetase NMB1595 [imported] - Neisseria meningitidis
(group B strain MD58) >gi|7226845|gb|AAF41948.1|
(AE002510) alanyl-tRNA synthetase [Neisseria
meningitidis MC58]
Length = 874
Score = 74.5 bits (180), Expect = 9e-13
Identities = 63/209 (30%), Positives = 95/209 (45%), Gaps = 26/209 (12%)
Query: 26 ALLLDQTIFYPTGGGQPHDRGTI----NGVEVLDVYKDEEGNVWHV-VKEPEKFKVGDEV 80
A+++D T FY GGQ D G I N EV D K + V+ + KVGD V
Sbjct: 487 AVVIDFTPFYAESGGQVGDVGYIFSGENRFEVRDTQKIKAAVFGQFGVQTSGRLKVGDSV 546
Query: 81 ELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKGRYDIAYPENL--- 137
K+D + R MR H+ HL+ L +VLG E GS ++ E R+DI++P+ +
Sbjct: 547 TAKVDDEIRNANMRNHSATHLMHKALRDVLGR-HVEQKGSLVTAESTRFDISHPQAVTAE 605
Query: 138 ------NKYKEQIIS--------LFNKYVDEGGEVKIWWE---GETRYTQIRDFEVIPCG 180
+ E I++ + + + G + ++ E E R Q+ F CG
Sbjct: 606 EIAEVERRVNEAILANVAVNAAIMSMEDAQKTGAMMLFGEKYGEEVRVLQMGGFSTELCG 665
Query: 181 GTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
GTHV +IG K + I G +R+E
Sbjct: 666 GTHVSRTGDIGLFKIISEGGIAAGVRRIE 694
>dbj|BAB10601.1| (AB005243) alanyl-tRNA synthetase [Arabidopsis thaliana]
Length = 954
Score = 74.5 bits (180), Expect = 9e-13
Identities = 64/223 (28%), Positives = 103/223 (45%), Gaps = 32/223 (14%)
Query: 18 KVVEIKDNALLLDQTIFYPTGGGQPHDRGTI----NG------VEVLDVYKDEEGNVWHV 67
+V E + +LLD+T FY GGQ D G + +G VEV DV K + V
Sbjct: 543 RVSEGSEVEVLLDRTPFYAESGGQIADHGFLYVSSDGNQEKAVVEVSDVQKSLKIFVHKG 602
Query: 68 VKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKG 127
+ +VG EVE +D D R + HT HLL+ L +V+G+ + GS ++ ++
Sbjct: 603 TVKSGALEVGKEVEAAVDADLRQRAKVHHTATHLLQSALKKVVGQ-ETSQAGSLVAFDRL 661
Query: 128 RYDIAYPENLNKYK-EQIISLFNKYVDEGG--EVKI------------------WWEGET 166
R+D + +L+ + E+I L N+++ + E K+ + E E
Sbjct: 662 RFDFNFNRSLHDNELEEIECLINRWIGDATRLETKVLPLADAKRAGAIAMFGEKYDENEV 721
Query: 167 RYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
R ++ + CGGTHV + EI K + I G +R+E
Sbjct: 722 RVVEVPGVSMELCGGTHVGNTAEIRAFKIISEQGIASGIRRIE 764
>sp|Q9X1B6|SYA_THEMA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437634|pir||E72259 alanine--tRNA ligase (EC
6.1.1.7) - Thermotoga maritima (strain MSB8)
>gi|4981959|gb|AAD36467.1|AE001792_7 (AE001792)
alanyl-tRNA synthetase [Thermotoga maritima]
Length = 863
Score = 73.7 bits (178), Expect = 2e-12
Identities = 62/227 (27%), Positives = 110/227 (48%), Gaps = 31/227 (13%)
Query: 8 EDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTI---NGVEVLD-VYKDEEGN 63
+D ++EA VE+ + +T FY GGQ D G + +G +++ V++ EG
Sbjct: 473 DDETVEEASEGTVEV-----VFSRTPFYAEKGGQVSDTGMVEWRDGKALVEYVFEASEGV 527
Query: 64 VWHVVKEPE-KFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGM 122
+ H +K + + G +V L++D R MR HT HLL L +VLG+ + GS +
Sbjct: 528 IVHRIKILDGTLRRGQKVILRVDKKRREATMRNHTATHLLHAALKKVLGDHVRQ-AGSLV 586
Query: 123 SVEKGRYDIAYPENLNKYK-EQIISLFNKYVDEGGEVKIWWEG-------------ETRY 168
+ ++ R+D + + L+ + EQ+ L N+++ E V++ + +Y
Sbjct: 587 APDRLRFDFTHFKGLSSAEIEQVEDLVNEWIMEAIPVEVRYTSYEEAVKSGVVALFTEKY 646
Query: 169 TQIRDFEVIP------CGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
+ +P CGGTHVK+ +IG K + S+ G +R+E
Sbjct: 647 GDVVRVVEVPGVSKELCGGTHVKNTGQIGLFKIISEESVSSGVRRIE 693
>gb|AAG23137.1|AF245445_1 (AF245445) alanyl-tRNA synthetase [Giardia intestinalis]
Length = 954
Score = 73.7 bits (178), Expect = 2e-12
Identities = 71/244 (29%), Positives = 107/244 (43%), Gaps = 44/244 (18%)
Query: 7 YEDAYLKEAKAKVVEI---------KDNALLLDQTIFYPTGGGQPHDRGTI-----NGV- 51
Y + K A AKVV I N ++LD+T+FYPT GGQ HD G + NG
Sbjct: 523 YGEKLRKLADAKVVSIFANMEDKSKGRNLVILDKTVFYPTSGGQQHDTGVLKFLLGNGKM 582
Query: 52 ---EVLDVYKDEEGNVWHVVKEP--EKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVL 106
+V+DV K V H + P + G V + ID R +LM HT H++
Sbjct: 583 IIHDVVDVRKVGH-CVMHELNAPVADSIVQGTSVSMAIDSARRDQLMCHHTAAHVIHATA 641
Query: 107 NEVLGEGKWELVGSGMSVEKGRYDIAYPENLNKYKEQIISL-FNKYVDEGGEVKIWW--- 162
N+VLG W+ G+ + E DI + +L +E+ I N+ + + ++ +
Sbjct: 642 NKVLGPHVWQ-AGAKKTTEVATLDITHYRSLTFDEERAIEREANRMIRDNIPIRKYQLPK 700
Query: 163 -EGETRY-----------------TQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRG 204
E E +Y I D + C GTH+ + +IG I+ +K + I G
Sbjct: 701 NEAEKKYGFSLYQGGVVPGSTVRCVDITDHDTEACCGTHLDNTGKIGLIRIVKSTRISDG 760
Query: 205 KQRL 208
RL
Sbjct: 761 VVRL 764
>sp|Q56273|SYA_THIFE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1263913|emb|CAA64818.1| (X95571) alanyl-tRNA
synthetase [Thiobacillus ferrooxidans]
Length = 877
Score = 73.0 bits (176), Expect = 3e-12
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 26/208 (12%)
Query: 27 LLLDQTIFYPTGGGQPHDRGTINGVEVLDVYKDEEGNVWHVVK-----EPEKFKVGDEVE 81
++LD+T FY GGQ DRG + + L D + + H+ E + ++GD V
Sbjct: 491 VILDRTPFYGESGGQAGDRGELQSNDALFAVTDTQKPMGHLHVHLGRVESGRLQIGDMVV 550
Query: 82 LKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKGRYDIAYPENLNKYK 141
+D R H+ HLL L +LG + GS ++ E+ R+D ++PE + +
Sbjct: 551 ASVDEVARRATAAHHSATHLLHAALRNILGSHVQQK-GSLVNPERLRFDFSHPEPVTAAQ 609
Query: 142 -EQIISLFNKYV--DEGGEVKIW-----------------WEGETRYTQIRDFEVIPCGG 181
+I + N + + G E +I + E R ++ DF + CGG
Sbjct: 610 LREIERVVNAAIRNNVGAETRILPVAEAQALGAMALFGEKYGDEVRVVRMGDFSMELCGG 669
Query: 182 THVKDIKEIGHIKKLKRSSIGRGKQRLE 209
THV+ + +IG K L S + G +R+E
Sbjct: 670 THVEALGDIGVFKILSESGVAAGIRRIE 697
>gb|AAF05594.1|AF188719_1 (AF188719) alanyl-tRNA synthetase [Giardia intestinalis]
Length = 969
Score = 72.6 bits (175), Expect = 4e-12
Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 52/248 (20%)
Query: 7 YEDAYLKEAKAKVVEI---------KDNALLLDQTIFYPTGGGQPHDRGTI-----NGV- 51
Y + K A AKVV I N ++LD+T+FYPT GGQ HD G + NG
Sbjct: 538 YGEKLRKLADAKVVSIFANMEDKSKGRNLVILDKTVFYPTSGGQQHDTGVLKFLLGNGKM 597
Query: 52 ---EVLDVYKDEEGNVWHVVKEP--EKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVL 106
+V+DV K V H + P + G V + ID R +LM HT H++
Sbjct: 598 IIHDVVDVRKVGH-CVMHELNAPVADSIVQGTSVSMAIDSARRDQLMCHHTAAHVIHATA 656
Query: 107 NEVLGEGKWELVGSGMSVEKGRYDIAYPENLNKYKEQIISL-----------FNKY---- 151
N+VLG W+ G+ + E DI + +L +E+ I KY
Sbjct: 657 NKVLGPHVWQ-AGAKKTTEVATLDITHYRSLTFDEERAIEREANRMIRDNIPIRKYQLPK 715
Query: 152 ----------VDEGGEVKIWWEGET-RYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSS 200
+ +GG V G T R I D + C GTH+ + +IG I+ +K +
Sbjct: 716 NKAEKKYGFSLYQGGVV----PGSTVRCVDITDHDTEACCGTHLDNTGKIGLIRIVKSTR 771
Query: 201 IGRGKQRL 208
I G RL
Sbjct: 772 ISDGVVRL 779
>sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437614|pir||S76394 hypothetical protein -
Synechocystis sp. (strain PCC 6803)
>gi|1653611|dbj|BAA18523.1| (D90915) alanyl-tRNA
synthetase [Synechocystis sp.]
Length = 877
Score = 72.2 bits (174), Expect = 5e-12
Identities = 58/207 (28%), Positives = 92/207 (44%), Gaps = 25/207 (12%)
Query: 27 LLLDQTIFYPTGGGQPHDRGTINGVEVL---DVYKDEEGNVWHVVK-EPEKFKVGDEVEL 82
++LDQT FY GGQ D+G +NG +L + K E G H + E ++G +
Sbjct: 489 IVLDQTPFYGESGGQIGDKGFLNGDNLLIRIEDVKRESGIFIHFGRVERGTVQIGTTITA 548
Query: 83 KIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKGRYDIAYPENLNKYK- 141
ID R + HT HLL+ L V+ EG + GS + + R+D P + +
Sbjct: 549 TIDRACRRRAQANHTATHLLQSALKRVVDEGISQ-AGSLVDFNRLRFDFNSPRAVTMEEL 607
Query: 142 EQIISLFNKYVDEGGEVKIW-------------------WEGETRYTQIRDFEVIPCGGT 182
+QI L N+++ E + ++ + E R + + CGGT
Sbjct: 608 QQIEDLINQWIAEAHQTEVAVMPIADAKAKGAIAMFGEKYGAEVRVIDVPGVSLELCGGT 667
Query: 183 HVKDIKEIGHIKKLKRSSIGRGKQRLE 209
HV + EIG K + + I G +R+E
Sbjct: 668 HVANTAEIGLFKIVAETGIAAGVRRIE 694
>sp|O34526|SYA_BACSU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437617|pir||A69584 alanine--tRNA ligase (EC
6.1.1.7) alaS - Bacillus subtilis
>gi|2635186|emb|CAB14682.1| (Z99117) alanyl-tRNA
synthetase [Bacillus subtilis]
>gi|2635204|emb|CAB14699.1| (Z99118) alanyl-tRNA
synthetase [Bacillus subtilis]
Length = 878
Score = 72.2 bits (174), Expect = 5e-12
Identities = 61/208 (29%), Positives = 99/208 (47%), Gaps = 26/208 (12%)
Query: 27 LLLDQTIFYPTGGGQPHDRGTING----VEVLDVYKDEEGNVWHV-VKEPEKFKVGDEVE 81
++LD+T FY GGQ D+G + V + DV K G H V E + G V
Sbjct: 492 IILDETPFYAESGGQIGDKGYLRSEQAVVRIKDVQKAPNGQHVHEGVVESGTVQKGLHVT 551
Query: 82 LKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKGRYDIAYPENLNKYK 141
+++ R +++ HT HLL L +VLG + GS ++ + R+D ++ + K +
Sbjct: 552 AEVEDHMRSGVIKNHTATHLLHQALKDVLGTHVNQ-AGSLVTENRLRFDFSHFGQVTKEE 610
Query: 142 -EQIISLFNKYV----------------DEGGEVKIWWE--GE-TRYTQIRDFEVIPCGG 181
EQI + N+ + E G + ++ E G+ R Q+ D+ + CGG
Sbjct: 611 LEQIERIVNEKIWASIPVSIDLKPIAEAKEMGAMALFGEKYGDIVRVVQVGDYSLELCGG 670
Query: 182 THVKDIKEIGHIKKLKRSSIGRGKQRLE 209
HV++ EIG K + S IG G +R+E
Sbjct: 671 CHVRNTAEIGLFKIVSESGIGAGTRRIE 698
>gb|AAF45874.1| (AE003427) CG10802 gene product [Drosophila melanogaster]
Length = 297
Score = 71.4 bits (172), Expect = 8e-12
Identities = 60/229 (26%), Positives = 97/229 (42%), Gaps = 44/229 (19%)
Query: 8 EDAYLKEAKAKVV-----------------EIKDNALLLDQTIFYPTGGGQPHDRGTING 50
ED++LKE K K+V ++K ++ + TI +P GGGQP D GT+ G
Sbjct: 7 EDSFLKEFKTKIVSSEFATLDWTDPSGKVEKLKGFNVICEDTILFPEGGGQPCDYGTLGG 66
Query: 51 VEVLDVYKDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVL 110
V +V + V H V+ P F+ EV L +D+ R M+ H+G HL+ + +
Sbjct: 67 FPVKNVQRKGSTAV-HFVESPTSFEQDAEVLLTLDYQRRLDHMQQHSGQHLITALFDR-- 123
Query: 111 GEGKWELVGSGMSVEKGRYDIAYPENLNKYKEQIIS-LFNKYVDEGGEVKIW-------- 161
E K++ + ++ P +++ +I N + EG EV +
Sbjct: 124 -EFKYDTTSWSLGSTVSYIQLSTPHLISRESLDLIERQANDLIREGREVTVLLVDPEVAQ 182
Query: 162 --------------WEGETRYTQIRDFEVIPCGGTHVKDIKEIGHIKKL 196
EG R +I E C GTHV ++ ++ IK L
Sbjct: 183 EFQDARAPRGLPKDHEGLARVVRIEGIESNMCCGTHVTNLSQLQCIKLL 231
>sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437635|pir||H71647 alanine--tRNA ligase (EC
6.1.1.7) (alaS) RP856 - Rickettsia prowazekii
>gi|3861381|emb|CAA15280.1| (AJ235273) ALANYL-TRNA
SYNTHETASE (alaS) [Rickettsia prowazekii]
Length = 877
Score = 71.0 bits (171), Expect = 1e-11
Identities = 61/239 (25%), Positives = 107/239 (44%), Gaps = 44/239 (18%)
Query: 12 LKEAKAKVVEIKDNALLLD--------------QTIFYPTGGGQPHDRGTI----NGVEV 53
L EA+ K++ + N L+D QT FY GGQ D G I + +EV
Sbjct: 464 LNEAECKIIALIKNNNLVDNIQEINTQFLLIANQTPFYGESGGQMGDIGMIFSQGSEIEV 523
Query: 54 LDVYKDEEGNVWH-VVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGE 112
+D +K + H + + K +G+ L I+ YR L H+ H+L VL+++LG+
Sbjct: 524 IDTFKYLRSIIVHKCILKKGKINIGENANLNINIRYRQNLRIHHSATHILHAVLHKILGK 583
Query: 113 GKWELVGSGMSVEKG--RYDIAYPENLNKYKEQIIS-----------------LFNKYVD 153
+++ G V R+DI + + + + +I +F +
Sbjct: 584 ---QVIQKGSLVTSTYLRFDINHSKAITNQEITLIEDQVNEIIRNNHEVTTTVMFTEDAI 640
Query: 154 EGGEVKIW---WEGETRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
+ G + ++ ++ E R +I + + C GTHVK +IG K + S+I G +R+E
Sbjct: 641 KQGAIALFGEKYDSEVRVVKIGETSLELCCGTHVKRTGDIGSFKIISESAIAAGVRRIE 699
>pir||G72685 probable alanyl-tRNA synthetase APE0903 - Aeropyrum pernix (strain
K1) >gi|5104572|dbj|BAA79887.1| (AP000060) 274aa long
hypothetical alanyl-tRNA synthetase [Aeropyrum pernix]
Length = 274
Score = 71.0 bits (171), Expect = 1e-11
Identities = 69/239 (28%), Positives = 110/239 (45%), Gaps = 35/239 (14%)
Query: 5 LYYEDAYLKEAKAKVVEIKDNALLLDQTIFYP-TGGGQPHDRGTI--NGVEVLDVYKDEE 61
LY +D+YL+E +A+V E ++LD+T F+P GG D G I V E
Sbjct: 31 LYQQDSYLREFEARVEEASGGRVVLDRTAFHPGPHGGLDTDTGYIFYGDKRYRVVRAAVE 90
Query: 62 GNV--WHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVG 119
G+V ++ + + G V+ IDW+ RY++MR+HT H+L VL E + + G
Sbjct: 91 GDVVAHYLDSDTATLEPGAVVKGVIDWERRYRMMRLHTFSHILAAVLYE---KHDVLVTG 147
Query: 120 SGMSVEKGRYDIAYPENLNKYKEQIISLF---NKYVDEGGEVKIWW-------------- 162
++ + G+ D + ++E I F N+ EVK++W
Sbjct: 148 GHITPDYGKDDFSIEG--GGWREVIEEAFREANEIASRCIEVKVYWLPREEALKIPGIVK 205
Query: 163 -------EGET-RYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWLE 213
E ET R +I +V GG HV++ EIG + K S G+ ++R+ LE
Sbjct: 206 LANKLPPEVETLRIVEIPGVDVQADGGPHVRNTCEIGRVVITKLESKGKRRKRVYYTLE 264
>gb|AAG23689.1|AF297520_1 (AF297520) alanyl-tRNA synthase [Haemophilus ducreyi]
Length = 783
Score = 70.2 bits (169), Expect = 2e-11
Identities = 63/222 (28%), Positives = 98/222 (43%), Gaps = 29/222 (13%)
Query: 14 EAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGTIN------GVEVLDVYKDEEGNVWHV 67
+A KV + ++LD+T FY GGQ D G I V Y G++ V
Sbjct: 386 QAVDKVQSGESAVVVLDKTPFYAEMGGQVGDSGLITTAFCQFAVADTQKYGQVFGHIGQV 445
Query: 68 VKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELVGSGMSVEKG 127
V +GD + ++D R + H+ HLL L +VLGE + GS +S
Sbjct: 446 VSG--SLAIGDIISAQVDIARRQAITANHSATHLLHSALRQVLGEHVVQK-GSLVSENVL 502
Query: 128 RYDIAYPENLNKYK-EQIISLFNKYV----------------DEGGEVKIWWE---GETR 167
R+D + + ++K + E+I + N+ + E G V ++ E R
Sbjct: 503 RFDFSQSQAVSKAQLEEIERIVNRQIRQNLAVTIETMDIETAKEKGTVALFGEKYGDVVR 562
Query: 168 YTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLE 209
+ DF + CGGTHVK EIG K + S++ G +R+E
Sbjct: 563 VVGMTDFSIELCGGTHVKHTGEIGLFKLISESAVAAGIRRVE 604
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.140 0.424
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90158675
Number of Sequences: 2977
Number of extensions: 4087928
Number of successful extensions: 9218
Number of sequences better than 1.0e-10: 34
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 9143
Number of HSP's gapped (non-prelim): 36
length of query: 213
length of database: 189,106,746
effective HSP length: 51
effective length of query: 162
effective length of database: 158,583,909
effective search space: 25690593258
effective search space used: 25690593258
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 163 (67.9 bits)