BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0068 (RfcS) DE:activator 1, replication factor C, small
subunit
(1437 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75198 activator 1, replication factor c, small chain PAB00... 2844 0.0
pir||F71231 probable replication factor C subunit - Pyrococcus h... 898 0.0
pir||E64477 replication factor C homolog - Methanococcus jannasc... 846 0.0
dbj|BAB03292.1| (AB037375) replication factor C small subunit pr... 341 3e-92
gi|11499642 activator 1, replication factor C, 35 KD subunit [Ar... 201 5e-50
pir||B69130 replication factor C, small subunit - Methanobacteri... 199 1e-49
pir||C72633 probable replication factor C subunit APE1522 - Aero... 193 1e-47
gb|AAG20394.1| (AE005112) replication factor C small subunit; Rf... 191 5e-47
emb|CAB57535.1| (Y18930) activator 1, replication factor C, smal... 184 5e-45
gb|AAK41065.1| Activator 1, replication factor C, small subunit ... 184 5e-45
sp|Q58095|Y682_METJA HYPOTHETICAL PROTEIN MJ0682 >gi|2129103|pir... 163 1e-38
pir||A64430 DNA-directed RNA polymerase (EC 2.7.7.6) subunit A' ... 161 5e-38
sp|Q58445|RPA1_METJA DNA-DIRECTED RNA POLYMERASE SUBUNIT A' >gi|... 161 5e-38
emb|CAC12618.1| (AL445067) probable replication factor C, 40 KD ... 147 7e-34
pir||C75175 hypothetical protein PAB0383 - Pyrococcus abyssi (st... 145 4e-33
gi|6677723 replication factor C (activator 1) 5 (36.5kD) [Homo s... 127 1e-27
sp|P53034|AC14_DROME ACTIVATOR 1 40 KDA SUBUNIT (REPLICATION FAC... 126 1e-27
gi|6324478 Subunit 4 of Replication Factor C; homologous to huma... 122 2e-26
dbj|BAB03291.1| (AB037375) replication factor C small subunit pr... 118 4e-25
sp|P53033|AC14_CHICK ACTIVATOR 1 40 KD SUBUNIT (REPLICATION FACT... 117 7e-25
gb|AAF69583.1|AC019154_2 (AC019154) Replication Factor C [Leishm... 117 1e-24
gi|11177922 replication factor C (activator 1) 2 (40kD) [Mus mus... 116 1e-24
dbj|BAB16439.1| (AB038319) replication factor C 36kDa subunit [O... 116 2e-24
pir||T37746 activator 1 subunit (replication factor subunit) - f... 115 5e-24
pir||A42700 replication factor C - human 114 8e-24
gi|4506487 replication factor C (activator 1) 2 (40kD) [Homo sap... 114 8e-24
gb|AAF21015.1|AF208499_1 (AF208499) replication factor C subunit... 113 1e-23
gb|AAF52944.1| (AE003628) RfC3 gene product [Drosophila melanoga... 113 1e-23
gb|AAF63387.1|AF247499_1 (AF247499) replication factor C subunit... 113 1e-23
pir||B71039 hypothetical protein PH1602 - Pyrococcus horikoshii ... 112 3e-23
pir||G71213 probable H(+)-transporting ATP synthase subunit A - ... 111 7e-23
gb|AAF18689.1|AC010795_4 (AC010795) replication factor, putative... 110 1e-22
gb|AAG21804.1|AF210454_2 (AF210454) replication factor C subunit... 108 4e-22
sp|P34429|AC11_CAEEL PUTATIVE ACTIVATOR 1 36 KD SUBUNIT (REPLICA... 108 5e-22
emb|CAA07618.1| (AJ007712) replication factor C subunit [Arxula ... 107 1e-21
pir||D75028 h+-transporting ATP synthase, chain alpha (atpa) PAB... 107 1e-21
gb|AAF07781.1|AC010704_6 (AC010704) putative replication factor ... 106 1e-21
gi|4506491 replication factor C (activator 1) 4 (37kD) [Homo sap... 103 2e-20
dbj|BAB16441.1| (AB045677) replication factor C 37kDa subunit [O... 103 2e-20
pir||T43410 replication factor C chain Rfc3 - fission yeast (Sc... 101 8e-20
gb|AAB88360.1| (AF036699) strong similarity to the activator 1 3... 100 1e-19
pir||T38458 replication factor 3 subunit - fission yeast (Schiz... 100 1e-19
pir||A45253 activator 1 37K chain - human 99 4e-19
gb|AAG37985.1|AF069296_1 (AF069296) replication factor C3 [Plasm... 98 5e-19
gi|6324039 Subunit 3 of Replication Factor C; homologous to huma... 98 9e-19
gb|AAF48768.1| (AE003506) CG8142 gene product [Drosophila melano... 97 2e-18
sp|Q09843|RFC2_SCHPO PROBABLE ACTIVATOR 1 41 KD SUBUNIT (REPLICA... 96 2e-18
gb|AAD41422.1|AC007727_11 (AC007727) Similar to gb|M87339 replic... 95 5e-18
gi|6322528 Subunit 2 of Replication Factor C; homologous to huma... 89 3e-16
emb|CAA06481.1| (AJ005334) replication factor C/activator 1 subu... 89 5e-16
pir||H71604 replication factor C, 40 kDa subunit (replication ac... 89 5e-16
gb|AAG37987.1|AF071409_1 (AF071409) replication factor C subunit... 89 5e-16
emb|CAB92098.1| (AL356333) Replication factor C 36 KD subunit; a... 86 2e-15
sp|P53016|AC12_CAEEL PUTATIVE ACTIVATOR 1 37 KD SUBUNIT (REPLICA... 84 1e-14
gb|AAG20362.1| (AE005110) replication factor C small subunit; Rf... 71 9e-11
>pir||C75198 activator 1, replication factor c, small chain PAB0068 - Pyrococcus
abyssi (strain Orsay) >gi|5457543|emb|CAB49034.1|
(AJ248283) activator 1, replication factor C, small
subunit [Pyrococcus abyssi]
Length = 1437
Score = 2844 bits (7291), Expect = 0.0
Identities = 1437/1437 (100%), Positives = 1437/1437 (100%)
Query: 1 MRDMEEVREVKVLEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVG 60
MRDMEEVREVKVLEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVG
Sbjct: 1 MRDMEEVREVKVLEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVG 60
Query: 61 KCLTGDAKVIANGELTTIGELVERISNGKLGPTPVRGLTVLGIDEDGKLVELPVEYVYKD 120
KCLTGDAKVIANGELTTIGELVERISNGKLGPTPVRGLTVLGIDEDGKLVELPVEYVYKD
Sbjct: 61 KCLTGDAKVIANGELTTIGELVERISNGKLGPTPVRGLTVLGIDEDGKLVELPVEYVYKD 120
Query: 121 KTSELVKIRTRLGRELKVTPYHPLLVNRRNGKIEWVKAEELKPGDRLAIPSFLPAMLNDN 180
KTSELVKIRTRLGRELKVTPYHPLLVNRRNGKIEWVKAEELKPGDRLAIPSFLPAMLNDN
Sbjct: 121 KTSELVKIRTRLGRELKVTPYHPLLVNRRNGKIEWVKAEELKPGDRLAIPSFLPAMLNDN 180
Query: 181 PLAEWLGYFFGNGYTDSEERVVFESKSKELRKRFMELTRKLFQDAEIKEDSGKVYVSSSE 240
PLAEWLGYFFGNGYTDSEERVVFESKSKELRKRFMELTRKLFQDAEIKEDSGKVYVSSSE
Sbjct: 181 PLAEWLGYFFGNGYTDSEERVVFESKSKELRKRFMELTRKLFQDAEIKEDSGKVYVSSSE 240
Query: 241 VKRLVKSLNKDSIPEQAWKGLRSFLRAYFDCNAEIKDKIIVSTAGKEIAEQISYALAGLG 300
VKRLVKSLNKDSIPEQAWKGLRSFLRAYFDCNAEIKDKIIVSTAGKEIAEQISYALAGLG
Sbjct: 241 VKRLVKSLNKDSIPEQAWKGLRSFLRAYFDCNAEIKDKIIVSTAGKEIAEQISYALAGLG 300
Query: 301 IVAEVDDKGSVIISDPENVSRFLDEIGFSVEEKKEEAKALIKKSTLNLGIYVDKELISYV 360
IVAEVDDKGSVIISDPENVSRFLDEIGFSVEEKKEEAKALIKKSTLNLGIYVDKELISYV
Sbjct: 301 IVAEVDDKGSVIISDPENVSRFLDEIGFSVEEKKEEAKALIKKSTLNLGIYVDKELISYV 360
Query: 361 REKLKLSFYENETMWSPEKAREIAWKLMKEIYYRLDELERFKKALSKSVIIDWSEVEKKK 420
REKLKLSFYENETMWSPEKAREIAWKLMKEIYYRLDELERFKKALSKSVIIDWSEVEKKK
Sbjct: 361 REKLKLSFYENETMWSPEKAREIAWKLMKEIYYRLDELERFKKALSKSVIIDWSEVEKKK 420
Query: 421 EEISEKTGISVNEILEYAKGKRKPSLEEYVKIAKALGVELKETLEAIFTFGKKYLGYVIS 480
EEISEKTGISVNEILEYAKGKRKPSLEEYVKIAKALGVELKETLEAIFTFGKKYLGYVIS
Sbjct: 421 EEISEKTGISVNEILEYAKGKRKPSLEEYVKIAKALGVELKETLEAIFTFGKKYLGYVIS 480
Query: 481 DEIETLEEVRKEELKRLKELLNDEKLKKGVAYLIFLAQNELLWDEIIEVEKLKGDFVIYD 540
DEIETLEEVRKEELKRLKELLNDEKLKKGVAYLIFLAQNELLWDEIIEVEKLKGDFVIYD
Sbjct: 481 DEIETLEEVRKEELKRLKELLNDEKLKKGVAYLIFLAQNELLWDEIIEVEKLKGDFVIYD 540
Query: 541 LHVPKYHNFIGGNLPTVLHNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKE 600
LHVPKYHNFIGGNLPTVLHNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKE
Sbjct: 541 LHVPKYHNFIGGNLPTVLHNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKE 600
Query: 601 FARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDE 660
FARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDE
Sbjct: 601 FARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDE 660
Query: 661 REVKIRDFMNYFENGLIKEVSNRIGRDTVIAAVSFNSRIVGHPVYRLTLESGRIIEATGD 720
REVKIRDFMNYFENGLIKEVSNRIGRDTVIAAVSFNSRIVGHPVYRLTLESGRIIEATGD
Sbjct: 661 REVKIRDFMNYFENGLIKEVSNRIGRDTVIAAVSFNSRIVGHPVYRLTLESGRIIEATGD 720
Query: 721 HMFLTPEGWKQTYDIKEGSEVLVKPTLEGTPYEPDPRVIIDIKEFYNFLEKIEREHNLKP 780
HMFLTPEGWKQTYDIKEGSEVLVKPTLEGTPYEPDPRVIIDIKEFYNFLEKIEREHNLKP
Sbjct: 721 HMFLTPEGWKQTYDIKEGSEVLVKPTLEGTPYEPDPRVIIDIKEFYNFLEKIEREHNLKP 780
Query: 781 LKEAKTFRELITKDKEKILRRALELRAEIENGLTKREAEILELISADTWIPRAELEKKAR 840
LKEAKTFRELITKDKEKILRRALELRAEIENGLTKREAEILELISADTWIPRAELEKKAR
Sbjct: 781 LKEAKTFRELITKDKEKILRRALELRAEIENGLTKREAEILELISADTWIPRAELEKKAR 840
Query: 841 ISRTRLNQILQRLEKKGYIERRIEGRKQFVRKIRNGKILRNAMDIKRILEEEFGIKISYT 900
ISRTRLNQILQRLEKKGYIERRIEGRKQFVRKIRNGKILRNAMDIKRILEEEFGIKISYT
Sbjct: 841 ISRTRLNQILQRLEKKGYIERRIEGRKQFVRKIRNGKILRNAMDIKRILEEEFGIKISYT 900
Query: 901 TVKKLLSGNVDGMAYRILKEVKEKWLVRYDDEKAGILARVVGFILGDGHLARNGRIWFNS 960
TVKKLLSGNVDGMAYRILKEVKEKWLVRYDDEKAGILARVVGFILGDGHLARNGRIWFNS
Sbjct: 901 TVKKLLSGNVDGMAYRILKEVKEKWLVRYDDEKAGILARVVGFILGDGHLARNGRIWFNS 960
Query: 961 SKEELEMLANDLRKLGLKPSEIIERDSSSEIQGRKVKGRIYMLYVDNAAFHALLRFWKVE 1020
SKEELEMLANDLRKLGLKPSEIIERDSSSEIQGRKVKGRIYMLYVDNAAFHALLRFWKVE
Sbjct: 961 SKEELEMLANDLRKLGLKPSEIIERDSSSEIQGRKVKGRIYMLYVDNAAFHALLRFWKVE 1020
Query: 1021 VGNKTKKGYTVPEWIKKGNLFVKREFLRGLFGADGTKPCGKRYNFNGIKLEIRAKKESLE 1080
VGNKTKKGYTVPEWIKKGNLFVKREFLRGLFGADGTKPCGKRYNFNGIKLEIRAKKESLE
Sbjct: 1021 VGNKTKKGYTVPEWIKKGNLFVKREFLRGLFGADGTKPCGKRYNFNGIKLEIRAKKESLE 1080
Query: 1081 RTVEFLNDVADLLREFDVDSKITVSPTKEGFIIRLIVTPNDANYLNFLTRVGYAYAKDTY 1140
RTVEFLNDVADLLREFDVDSKITVSPTKEGFIIRLIVTPNDANYLNFLTRVGYAYAKDTY
Sbjct: 1081 RTVEFLNDVADLLREFDVDSKITVSPTKEGFIIRLIVTPNDANYLNFLTRVGYAYAKDTY 1140
Query: 1141 ARLVGEYIRIKLAYKNIILPGIAEKAIELATVTNSTYAAKVLGVSRDFVVNRLKGTQIGI 1200
ARLVGEYIRIKLAYKNIILPGIAEKAIELATVTNSTYAAKVLGVSRDFVVNRLKGTQIGI
Sbjct: 1141 ARLVGEYIRIKLAYKNIILPGIAEKAIELATVTNSTYAAKVLGVSRDFVVNRLKGTQIGI 1200
Query: 1201 TRDFMTFEEFMKERVLNGYVIEKVIKKEKLGYLDVYDVTCARDHSFISNGLVSHNCNYSS 1260
TRDFMTFEEFMKERVLNGYVIEKVIKKEKLGYLDVYDVTCARDHSFISNGLVSHNCNYSS
Sbjct: 1201 TRDFMTFEEFMKERVLNGYVIEKVIKKEKLGYLDVYDVTCARDHSFISNGLVSHNCNYSS 1260
Query: 1261 KIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINI 1320
KIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINI
Sbjct: 1261 KIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINI 1320
Query: 1321 LQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGED 1380
LQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGED
Sbjct: 1321 LQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGED 1380
Query: 1381 VLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLIGKKK 1437
VLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLIGKKK
Sbjct: 1381 VLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLIGKKK 1437
>pir||F71231 probable replication factor C subunit - Pyrococcus horikoshii
>gi|3256498|dbj|BAA29181.1| (AP000001) 855aa long
hypothetical replication factor C subunit [Pyrococcus
horikoshii]
Length = 855
Score = 898 bits (2296), Expect = 0.0
Identities = 445/707 (62%), Positives = 561/707 (78%), Gaps = 29/707 (4%)
Query: 1 MRDMEEVREVKVLEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVG 60
M +MEEVREVKVLEKPWVEKYRPQ+L+EIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVG
Sbjct: 1 MHNMEEVREVKVLEKPWVEKYRPQRLDEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVG 60
Query: 61 KCLTGDAKVIANGELTTIGELVERISNGKLGPTPVRGLTVLGIDEDGKLVELPVEYVYKD 120
KCLTGD KVIANG+L + ELVE+IS GK GPTPV+GL V+GIDEDGKL E V+YVYKD
Sbjct: 61 KCLTGDTKVIANGQLFELRELVEKISGGKFGPTPVKGLKVIGIDEDGKLREFEVQYVYKD 120
Query: 121 KTSELVKIRTRLGRELKVTPYHPLLVNRRNGKIEWVKAEELKPGDRLAIPSFLPAMLNDN 180
KT L++IRTRLGRELKVTPYHPLLVNRRNG+I+WVKAEELKPGD+LA+P FLP + ++
Sbjct: 121 KTERLIRIRTRLGRELKVTPYHPLLVNRRNGEIKWVKAEELKPGDKLAVPRFLPIVTGED 180
Query: 181 PLAEWLGYFFGNGYTDSEER-VVFESKSKELRKRFMELTRKLFQDAEIKE-----DSGKV 234
PLAEWLGYF G GY DS+E ++F ++ LR+RFMELT KLF DA I+E + KV
Sbjct: 181 PLAEWLGYFLGGGYADSKENLIMFTNEDPLLRQRFMELTEKLFSDARIREITHENGTSKV 240
Query: 235 YVSSSEVKRLVKSLNKDSIPEQAWKGLRSFLRAYFDCNAEIK-DKIIVSTAGKEIAEQIS 293
YV+S + +LV SL IP++ W+G+RSFLRAYFDCN +K + I+++TA KE++++I+
Sbjct: 241 YVNSKKALKLVNSLGNAHIPKECWRGIRSFLRAYFDCNGGVKGNAIVLATASKEMSQEIA 300
Query: 294 YALAGLGIVAEVDDKGSVIISDPENVSRFLDEIGFSVEEKKEEAKALIKKSTL-NLGIYV 352
YALAG GI++ + + VIIS +NV +FL+EIGF K E+A L+KK + G+ +
Sbjct: 301 YALAGFGIISRIQEY-RVIISGSDNVKKFLNEIGFINRNKLEKALKLVKKDDPGHDGLEI 359
Query: 353 DKELISYVREKLKLSFYENETMWSPEKAREIAWKLMKEIYYRLDELERFKKALSKSVIID 412
+ ELISYV+++L+LSF+ ++ WS +A+EI+W+LMKEIYYRLDELE+ K++LS+ ++ID
Sbjct: 360 NYELISYVKDRLRLSFFNDKRSWSYREAKEISWELMKEIYYRLDELEKLKESLSRGILID 419
Query: 413 WSEVEKKKEEISEKTGISVNEILEYAKGKRKPSLEEYVKIAKALGVELKETLEAIFTFGK 472
W+EV K+ EE++E+TGI +E+LEY +GKRK S ++Y+KIAK LG++++ T+EA+ F +
Sbjct: 420 WNEVAKRIEEVAEETGIRADELLEYIEGKRKLSFKDYIKIAKVLGIDVEHTIEAMRVFAR 479
Query: 473 KYLGYV-------------------ISDEIETLEEVRKEELKRLKELLNDEKLKKGVAYL 513
KY Y + +E LE +RK EL+ ++E+L+DEKLK+G+AYL
Sbjct: 480 KYSSYAEIGRRLGTWNSSVKTILESNAVNVEILERIRKIELELIEEILSDEKLKEGIAYL 539
Query: 514 IFLAQNELLWDEIIEVEKLKGDFVIYDLHVPKYHNFIGGNLPTVLHNTTAALALARELFG 573
IFL+QNEL WDEI +VE+L+G+F+IYDLHVP YHNFI GN+PTV+HNTTAALAL+RELFG
Sbjct: 540 IFLSQNELYWDEITKVEELRGEFIIYDLHVPGYHNFIAGNMPTVVHNTTAALALSRELFG 599
Query: 574 ENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRR 633
ENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRR
Sbjct: 600 ENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRR 659
Query: 634 TMEMFSSNVRFILSCVTGDTKVYTPDEREVKIRDFMNYFENGLIKEV 680
TMEMFSSNVRFILSC +K+ P + I F + + K +
Sbjct: 660 TMEMFSSNVRFILSC-NYSSKIIEPIQSRCAIFRFRPLRDEDIAKRL 705
Score = 352 bits (893), Expect = 2e-95
Identities = 220/387 (56%), Positives = 257/387 (65%), Gaps = 51/387 (13%)
Query: 1066 NGIKLEIRAKKESLERTVEFLNDVADLLREFDVDSKITVSPTKEGFIIRLIVTPNDANYL 1125
N + +EI + +E +L+ E D K+ KEG + ++ N+ Y
Sbjct: 505 NAVNVEILERIRKIE---------LELIEEILSDEKL-----KEGIAYLIFLSQNEL-YW 549
Query: 1126 NFLTRVGYAYAKDTYARLVGEYIRIKL---AYKNIILPGIAEKAIELATVTNSTYAAKVL 1182
+ +T+V L GE+I L Y N I A + TV ++T AA L
Sbjct: 550 DEITKV---------EELRGEFIIYDLHVPGYHNFI-------AGNMPTVVHNTTAA--L 591
Query: 1183 GVSRDFV----------VNRLKGTQIGITRDFMTFEEFMKERVLNGYVIEKVIKKEKLGY 1232
+SR+ +N I + R+ + +EF + + + G K+I ++
Sbjct: 592 ALSRELFGENWRHNFLELNASDERGINVIREKV--KEFARTKPIGGASF-KIIFLDEADA 648
Query: 1233 L--DVYDVTCARDHSFISNGLVSHNCNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYI 1290
L D F SN +CNYSSKIIEPIQSRCAIFRFRPL DEDIAKRLRYI
Sbjct: 649 LTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYI 708
Query: 1291 AENEGLELTEEGLQAILYIAEGDMRRAINILQAAAALDRKITDENVFLVASRARPEDIRE 1350
AENEGLELTEEGLQAILYIAEGDMRRAINILQAAAALD+KITDENVF+VASRARPEDIRE
Sbjct: 709 AENEGLELTEEGLQAILYIAEGDMRRAINILQAAAALDKKITDENVFMVASRARPEDIRE 768
Query: 1351 MMLLALKGNFLKAREKLREILLKQGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYN 1410
MMLLALKGNFLKAREKLREILLKQGLSGEDVL+QMH+EVFNLPIDEP KVYLADKIGEYN
Sbjct: 769 MMLLALKGNFLKAREKLREILLKQGLSGEDVLIQMHKEVFNLPIDEPTKVYLADKIGEYN 828
Query: 1411 FRLVEGANEMIQLEALLAQFTLIGKKK 1437
FRLVEGANEMIQLEALLAQFTL+GKKK
Sbjct: 829 FRLVEGANEMIQLEALLAQFTLVGKKK 855
>pir||E64477 replication factor C homolog - Methanococcus jannaschii
>gi|1592072|gb|AAB99433.1| (U67583) activator 1
(replication factor C), 35 KD subunit [Methanococcus
jannaschii]
Length = 1847
Score = 846 bits (2162), Expect = 0.0
Identities = 469/970 (48%), Positives = 629/970 (64%), Gaps = 107/970 (11%)
Query: 477 YVISDEI-ETLEEVRKEELKRLKELLNDEKL----KKGVAYLIFLAQNELLWDEIIEVEK 531
Y++ ++ E + V K+++K++ E++N EKL K+ L L++ EL + E+E
Sbjct: 974 YILRHQLYEGKKRVSKDKIKQILEMVNVEKLSDKEKEVYDLLKKLSKTELYALVVKEIEI 1033
Query: 532 LKGDFVIYDLHVPKYHNFIGGNLPTVLHNTTAALALARELFGENWRHNFLELNASDERGI 591
+ + +YD+ VP F GN+P +LHN SDERGI
Sbjct: 1034 IDYNDFVYDVSVPNNEMFFAGNVPILLHN-------------------------SDERGI 1068
Query: 592 NVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTG 651
+VIR KVK+FARTKPIG FKIIFLDE+DALT DAQ ALRRTME +S RFILSC+TG
Sbjct: 1069 DVIRTKVKDFARTKPIGDVPFKIIFLDESDALTADAQNALRRTMEKYSDVCRFILSCLTG 1128
Query: 652 DTKVYTPDEREVKIRDFMNYFENGLIKEVSNRIGRDTVIAAVSFNSRIVGHPVYRLTLES 711
D K+ PDERE+KI DF+ FE +K V NR G D V+A V FNS+IV H VYRL LES
Sbjct: 1129 DAKITLPDEREIKIEDFIKMFEERKLKHVLNRNGEDLVLAGVKFNSKIVNHKVYRLVLES 1188
Query: 712 GRIIEATGDHMFLTPEGWKQTYDIKEGSEVLVKPTLEGTPYEPDPRVIIDIKEFYNFLEK 771
GR IEATGDH FLT +GWK+ Y++KE D V++ Y LE
Sbjct: 1189 GREIEATGDHKFLTRDGWKEVYELKE-----------------DDEVLV-----YPALEG 1226
Query: 772 IEREHNLKPLKEAKTFRELITKDKEKILRRALELRAEIENGLTKREAEILELISADTWIP 831
+ E + + + F E +T + K+ + L + +T+ + +IL +
Sbjct: 1227 VGFEVDERRIIGLNEFYEFLTNYEIKLGYKPLGKAKSYKELITRDKEKILSRV------- 1279
Query: 832 RAELEKKARISRTRLNQILQRLEKKGYIERRIEGRKQFVRKIRNGKILRNAMDIKRILEE 891
LE + S++ +I+R +EE
Sbjct: 1280 ---LELSDKYSKS---------------------------------------EIRRKIEE 1297
Query: 892 EFGIKISYTTVKKLLSGNVDGMAYRILKEVKEK-W-LVRYDDEKAGILARVVGFILGDGH 949
EFGIKIS TT+K L++G +DG A + ++++KE W + YDDEKAGI AR++GFI+GDGH
Sbjct: 1298 EFGIKISLTTIKNLINGKIDGFALKYVRKIKELGWDEITYDDEKAGIFARLLGFIIGDGH 1357
Query: 950 LARN--GRIWFNSSKEELEMLANDLRKLGLKPSEIIERDSSSEIQGRKVKGRIYMLYVDN 1007
L+++ GRI ++ ELE + DL KLG+K S IIE+D ++ GR++KG+ +Y++N
Sbjct: 1358 LSKSKEGRILITATINELEGIKKDLEKLGIKASNIIEKDIEHKLDGREIKGKTSFIYINN 1417
Query: 1008 AAFHALLRFWKVEVGNKTKKGYTVPEWIKKGNLFVKREFLRGLFGADGTKPCGKRYNFNG 1067
AF+ LL FW VE+GNKT GY +P+WIK GN FVKREFLRGLFGADGTKP K+YN NG
Sbjct: 1418 KAFYLLLNFWGVEIGNKTINGYNIPKWIKYGNKFVKREFLRGLFGADGTKPYIKKYNING 1477
Query: 1068 IKLEIRAKKESLERTVEFLNDVADLLREFDVDSKITVSPTKEGFIIRLIVTPNDANYLNF 1127
IKL IR + S ++T+EF +V +L EF+V+S I VS + LIV N+ NYL +
Sbjct: 1478 IKLGIRVENISKDKTLEFFEEVKKMLEEFEVESYIKVSKIDNKNLTELIVKANNKNYLKY 1537
Query: 1128 LTRVGYAYAKDTYARLVGEYIRIKLAYKNIILPGIAEKAIELATVTNSTYA-AKVLGVSR 1186
L+R+ YAY KD +ARLVGEY+RIK AYK+IIL IAE A++ A S A+ V
Sbjct: 1538 LSRISYAYEKDNFARLVGEYLRIKEAYKDIILKEIAENALKEADGEKSLRELARKYNVPV 1597
Query: 1187 DFVVNRLKGTQIGITRDFMTFEEFMKERVLNG-YVIEKVIKKEKLGYLDVYDVTCARDHS 1245
DF++N+LKG IG+ R+FMTFEEF+KE+V++G YV E++IKKE +GY DVYD+TC +D S
Sbjct: 1598 DFIINQLKGKDIGLPRNFMTFEEFLKEKVVDGKYVSERIIKKECIGYRDVYDITCHKDPS 1657
Query: 1246 FISNGLVSHNCNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQA 1305
FI+NG VSHNCNY SKII PIQSRCA+FRF PL EDIAK+L+ IAE EGL LTE GL+A
Sbjct: 1658 FIANGFVSHNCNYPSKIIPPIQSRCAVFRFSPLKKEDIAKKLKEIAEKEGLNLTESGLEA 1717
Query: 1306 ILYIAEGDMRRAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKARE 1365
I+Y++EGDMR+AIN+LQ AAAL I DE V+ V+SRARPE++++MM LAL G F++AR+
Sbjct: 1718 IIYVSEGDMRKAINVLQTAAALSDVIDDEIVYKVSSRARPEEVKKMMELALDGKFMEARD 1777
Query: 1366 KLREILLKQGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEA 1425
L +++++ G+SGED+L QM RE+ +L IDE KV LAD IGE +FR+VEGANE IQL A
Sbjct: 1778 LLYKLMVEWGMSGEDILNQMFREINSLDIDERKKVELADAIGETDFRIVEGANERIQLSA 1837
Query: 1426 LLAQFTLIGK 1435
LLA+ L+G+
Sbjct: 1838 LLAKMALMGR 1847
Score = 642 bits (1639), Expect = 0.0
Identities = 332/626 (53%), Positives = 439/626 (70%), Gaps = 49/626 (7%)
Query: 10 VKVLEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLTGDAKV 69
V ++EKPWVEKYRP+ L++IVGQ+ IVKRLK YV+ SMPHLLF+GPPGVGKCLTGD KV
Sbjct: 2 VIIMEKPWVEKYRPKTLDDIVGQDEIVKRLKKYVEKKSMPHLLFSGPPGVGKCLTGDTKV 61
Query: 70 IANGELTTIGELVERISNGKLGPTPVRGLTVLGIDEDGKLVELPVEYVYKDKTSELVKIR 129
I NGE+ IGE++E ISNGK G T L VLGIDEDGK+ E V+YVYKDKT+ L+KI+
Sbjct: 62 IVNGEIREIGEVIEEISNGKFGVTLTNNLKVLGIDEDGKIREFDVQYVYKDKTNTLIKIK 121
Query: 130 TRLGRELKVTPYHPLLVNRRNGKIEWVKAEELKPGDRLAIPSFLPAMLND--NPLAEWLG 187
T++GRELKVT YHPLL+N +NG+I+W KAE LK GD+LA P ++ +D LAEWLG
Sbjct: 122 TKMGRELKVTTYHPLLINHKNGEIKWEKAENLKVGDKLATPRYILFNESDYNEELAEWLG 181
Query: 188 YFFGNGYTDSE-ERVVFESKSKELRKRFMELTRKLFQDAEIKEDSGK-----VYVSSSEV 241
YF G+G+ D E ++ F + ++LRKRF ELT KLF+DA+IKE K +YV+S E
Sbjct: 182 YFIGDGHADKESNKITFTNGDEKLRKRFAELTEKLFKDAKIKERIHKDRTPDIYVNSKEA 241
Query: 242 KRLV-------KSLNKDSIPEQAWK--GLRSFLRAYFDCNAEI-KDKIIVSTAGKEIAEQ 291
+ K +K IP++ + LR+FLRAYFDC+ I K I++STA KE+AE
Sbjct: 242 VEFIDKLGLRGKKADKVRIPKEIMRSDALRAFLRAYFDCDGGIEKHSIVLSTASKEMAED 301
Query: 292 ISYALAGLGIVAEVDDKGS---------VIISDPENVSRFLDEIGFSVEEKKEEAKALIK 342
+ YAL GI+A++ +K + ++IS+ N+ FLD IGFS E K ++ +IK
Sbjct: 302 LVYALLRFGIIAKLREKVNKNNNKVYYHIVISNSSNLRTFLDNIGFSQERKLKKLLEIIK 361
Query: 343 KSTLNLG-IYVDKELISYVREKLKLSFYEN--ETMWSPEKAREIAWKLMKEIYYRLDELE 399
NL I +DKE I Y+R++LK+ + + WS K R+I +L+KEIYYRL+EL+
Sbjct: 362 DENPNLDVITIDKEKIRYIRDRLKVKLTRDIEKDNWSYNKCRKITQELLKEIYYRLEELK 421
Query: 400 RFKKALSKSVIIDWSEVEKKKEEISEKTGISVNEILEYAKGKRKPSLEEYVKIAKALGVE 459
+KAL ++++IDW EV ++++EI+EKTGI + ILEY +GKRKPSL+ Y+KIA LG
Sbjct: 422 EIEKALEENILIDWDEVAERRKEIAEKTGIRSDRILEYIRGKRKPSLKNYIKIANTLGKN 481
Query: 460 LKETLEAIFTFGKKYLGYV-------------------ISDEIETLEEVRKEELKRLKEL 500
+++ ++A+ F KKY Y + EIE LEE+RK ELK +KE+
Sbjct: 482 IEKIIDAMRIFAKKYSSYAEIGKMLNMWNSSIKIYLESNTQEIEKLEEIRKTELKLVKEI 541
Query: 501 LNDEKLKKGVAYLIFLAQNELLWDEIIEVEKLKGDFVIYDLHVPKYHNFIGGNLPTVLHN 560
LNDEKL + Y++FLA NE+ WDEI+E+E+L G+F IYDLHVP+YHNFIGGNLPT+LHN
Sbjct: 542 LNDEKLIDSIGYVLFLASNEIYWDEIVEIEQLNGEFTIYDLHVPRYHNFIGGNLPTILHN 601
Query: 561 TTAALALARELFGENWRHNFLELNAS 586
TTAAL LAR+LFGENWR NFLELNAS
Sbjct: 602 TTAALCLARDLFGENWRDNFLELNAS 627
>dbj|BAB03292.1| (AB037375) replication factor C small subunit precursor [Pyrococcus
furiosus]
Length = 268
Score = 341 bits (866), Expect = 3e-92
Identities = 176/191 (92%), Positives = 182/191 (95%)
Query: 1246 FISNGLVSHNCNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQA 1305
F SN +CNYSSKIIEPIQSRCAIFRFRPL DEDIAKRLRYIAENEGLELTEEGLQA
Sbjct: 78 FSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQA 137
Query: 1306 ILYIAEGDMRRAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKARE 1365
ILYIAEGDMRRAINILQAAAALD+KITDENVF+VASRARPEDIREMMLLALKGNFLKARE
Sbjct: 138 ILYIAEGDMRRAINILQAAAALDKKITDENVFMVASRARPEDIREMMLLALKGNFLKARE 197
Query: 1366 KLREILLKQGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEA 1425
KLREILLKQGLSGEDVLVQMH+EVFNLPI+EP KV LADKIGEYNFRLVEGANE+IQLEA
Sbjct: 198 KLREILLKQGLSGEDVLVQMHKEVFNLPIEEPKKVLLADKIGEYNFRLVEGANEIIQLEA 257
Query: 1426 LLAQFTLIGKK 1436
LLAQFTLIGKK
Sbjct: 258 LLAQFTLIGKK 268
Score = 176 bits (442), Expect = 1e-42
Identities = 93/120 (77%), Positives = 99/120 (82%), Gaps = 1/120 (0%)
Query: 561 TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEA 620
TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEA
Sbjct: 1 TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEA 60
Query: 621 DALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDEREVKIRDFMNYFENGLIKEV 680
DALTQDAQQALRRTMEMFSSNVRFILSC +K+ P + I F + + K +
Sbjct: 61 DALTQDAQQALRRTMEMFSSNVRFILSC-NYSSKIIEPIQSRCAIFRFRPLRDEDIAKRL 119
>gi|11499642 activator 1, replication factor C, 35 KD subunit [Archaeoglobus
fulgidus] >gi|7444552|pir||C69507 activator 1,
replication factor C, 35 KD subunit homolog -
Archaeoglobus fulgidus >gi|2648471|gb|AAB89191.1|
(AE000961) activator 1, replication factor C, 35 KD
subunit [Archaeoglobus fulgidus]
Length = 319
Score = 201 bits (506), Expect = 5e-50
Identities = 92/182 (50%), Positives = 138/182 (75%)
Query: 1255 NCNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDM 1314
+CNY S+IIEPIQSRCA+FRF+P+ E + KRL I E EG+++TE+GL+A++YI+ GD
Sbjct: 138 SCNYVSRIIEPIQSRCAVFRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDF 197
Query: 1315 RRAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQ 1374
R+AIN LQ AAA+ + + ++ + + ARPE++ E++ ALKGNF++ARE L ++++
Sbjct: 198 RKAINALQGAAAIGEVVDADTIYQITATARPEEMTELIQTALKGNFMEARELLDRLMVEY 257
Query: 1375 GLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLIG 1434
G+SGED++ Q+ RE+ ++PI + +KV L DK+GE +FRL EGANE IQL+A LA + +
Sbjct: 258 GMSGEDIVAQLFREIISMPIKDSLKVQLIDKLGEVDFRLTEGANERIQLDAYLAYLSTLA 317
Query: 1435 KK 1436
KK
Sbjct: 318 KK 319
Score = 146 bits (365), Expect = 2e-33
Identities = 79/125 (63%), Positives = 94/125 (75%), Gaps = 8/125 (6%)
Query: 524 DEIIEVEKLKGDFVIYDLHVPKYHNFIGGNLPTVLHNTTAALALARELFGENWRHNFLEL 583
DE+I+ +LKG + ++P H G P T A+ALAR+LFGENWR NF+E+
Sbjct: 23 DEVIQ--RLKG--YVERKNIP--HLLFSG--PPGTGKTATAIALARDLFGENWRDNFIEM 74
Query: 584 NASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVR 643
NASDERGI+V+R K+KEFART PIGGA FKIIFLDEADALT DAQ ALRRTMEM+S + R
Sbjct: 75 NASDERGIDVVRHKIKEFARTAPIGGAPFKIIFLDEADALTADAQAALRRTMEMYSKSCR 134
Query: 644 FILSC 648
FILSC
Sbjct: 135 FILSC 139
Score = 73.0 bits (176), Expect = 2e-11
Identities = 30/51 (58%), Positives = 41/51 (79%)
Query: 17 WVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLTGDA 67
WVEKYRP+ L+E+VGQ+ +++RLK YV+ ++PHLLF+GPPG GK T A
Sbjct: 7 WVEKYRPRTLDEVVGQDEVIQRLKGYVERKNIPHLLFSGPPGTGKTATAIA 57
>pir||B69130 replication factor C, small subunit - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621290|gb|AAB84747.1| (AE000811) replication factor
C, small subunit [Methanobacterium thermoautotrophicum]
Length = 321
Score = 199 bits (502), Expect = 1e-49
Identities = 101/180 (56%), Positives = 134/180 (74%), Gaps = 4/180 (2%)
Query: 1255 NCNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDM 1314
+CNYSSKII+PIQSRCAIFRF PL I KRL YIAE E LE L+ I+Y AEGD+
Sbjct: 138 SCNYSSKIIDPIQSRCAIFRFLPLKGHQIIKRLEYIAEKENLEYEAHALETIVYFAEGDL 197
Query: 1315 RRAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQ 1374
R+AIN+LQ+AA+L KIT+ +++ V SRARP+D+R+M+ L G F++AR+ LREI++ Q
Sbjct: 198 RKAINLLQSAASLGEKITESSIYDVVSRARPKDVRKMIKTILDGKFMEARDMLREIMVLQ 257
Query: 1375 GLSGEDVLVQMHREVFNL----PIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQF 1430
G+SGED++ Q+++E+ L +D V L D IGEY+FR+ EGAN IQLEALLA+F
Sbjct: 258 GISGEDMVTQIYQELSRLAMEGEVDGDRYVGLIDAIGEYDFRIREGANPRIQLEALLARF 317
Score = 121 bits (300), Expect = 7e-26
Identities = 65/126 (51%), Positives = 83/126 (65%), Gaps = 2/126 (1%)
Query: 555 PTVLHNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKI 614
P + TTAALALARE+ GE WR NFLELNASD RGI+ +R +K F R KP+ GA F+I
Sbjct: 47 PAGVGKTTAALALAREILGEYWRQNFLELNASDARGIDTVRTSIKNFCRLKPV-GAPFRI 105
Query: 615 IFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDEREVKIRDFMNYFEN 674
IFLDE D +T+DAQ ALRR MEM++ FILSC +K+ P + I F+ +
Sbjct: 106 IFLDEVDNMTKDAQHALRREMEMYTKTSSFILSC-NYSSKIIDPIQSRCAIFRFLPLKGH 164
Query: 675 GLIKEV 680
+IK +
Sbjct: 165 QIIKRL 170
Score = 85.4 bits (208), Expect = 4e-15
Identities = 85/309 (27%), Positives = 146/309 (46%), Gaps = 43/309 (13%)
Query: 12 VLEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLTGDAKVIA 71
++ PWVEKYRPQKL++IVGQEHI+ RLK YV+ SMP+L+F GP GVGK T A +A
Sbjct: 3 IMNGPWVEKYRPQKLDDIVGQEHIIPRLKRYVEEKSMPNLMFTGPAGVGK--TTAALALA 60
Query: 72 NGELTTIGELVERISNGKLGPTPVRGLTVLGIDEDG----KLVELPVEYVYKDKTSELVK 127
+GE R + +L + RG+ + K V P ++ D+ + K
Sbjct: 61 R---EILGE-YWRQNFLELNASDARGIDTVRTSIKNFCRLKPVGAPFRIIFLDEVDNMTK 116
Query: 128 -IRTRLGRELKV---TPYHPLLVNRRNGKIEWVKAEELKPGDRLAIPSFLPAMLNDNPLA 183
+ L RE+++ T L N + I+ +++ R AI FLP L + +
Sbjct: 117 DAQHALRREMEMYTKTSSFILSCNYSSKIIDPIQS-------RCAIFRFLP--LKGHQII 167
Query: 184 EWLGYFFGNGYTDSEERVVFESKSKELRKRFMELTRKLFQDAEIKEDSGKVYVSSSEVKR 243
+ L Y +E + +E+ + E T F + ++++ + ++S ++
Sbjct: 168 KRLEYI------AEKENLEYEAHALE--------TIVYFAEGDLRKAINLLQSAASLGEK 213
Query: 244 LVKSLNKDSIPEQAWKGLRSFLRAYFDCN-AEIKD-----KIIVSTAGKEIAEQISYALA 297
+ +S D + K +R ++ D E +D ++ +G+++ QI L+
Sbjct: 214 ITESSIYDVVSRARPKDVRKMIKTILDGKFMEARDMLREIMVLQGISGEDMVTQIYQELS 273
Query: 298 GLGIVAEVD 306
L + EVD
Sbjct: 274 RLAMEGEVD 282
>pir||C72633 probable replication factor C subunit APE1522 - Aeropyrum pernix
(strain K1) >gi|5105207|dbj|BAA80521.1| (AP000061) 346aa
long hypothetical replication factor C subunit [Aeropyrum
pernix]
Length = 346
Score = 193 bits (486), Expect = 1e-47
Identities = 98/182 (53%), Positives = 138/182 (74%), Gaps = 3/182 (1%)
Query: 1257 NYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRR 1316
NY SKII+PIQSRCA FRF+PL+ +D+ +RLRYIAENEG++ EE L AI I+EGDMR+
Sbjct: 163 NYPSKIIDPIQSRCAFFRFQPLSKQDVIERLRYIAENEGVDYEEEALDAIYEISEGDMRK 222
Query: 1317 AINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGL 1376
AIN+LQAA+ L K+T + V+ V A+P ++REM+ ALKG+F AR LR+I+++ G+
Sbjct: 223 AINVLQAASYLG-KVTVDAVYRVVGMAKPREVREMLATALKGDFTAARSLLRKIMIEYGM 281
Query: 1377 SGEDVLVQMHREVFN--LPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLIG 1434
SGEDV Q+HRE+F+ L + E ++V AD +GE ++RLVEG+++ IQL A LA T++
Sbjct: 282 SGEDVARQIHRELFSTELKMPEELRVLAADYLGEVHYRLVEGSDDDIQLSAFLAWLTMMS 341
Query: 1435 KK 1436
+K
Sbjct: 342 RK 343
Score = 118 bits (293), Expect = 4e-25
Identities = 73/136 (53%), Positives = 88/136 (64%), Gaps = 11/136 (8%)
Query: 520 ELLWDEIIEVEKLKGDFVIYDLHV-PKYHNFIGG-NLPTVLH-------NTTAALALARE 570
E+LW E L D ++ HV + F+ N+P +L TTAA ALA +
Sbjct: 27 EMLWVEKYRPRSL--DDIVDQKHVVERLKQFVKQRNMPHLLFAGPPGTGKTTAAHALAHD 84
Query: 571 LFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQA 630
LFGEN+R LELNASDERGINVIREKVKEFAR++ FKI+ LDEAD +T DAQQA
Sbjct: 85 LFGENYRQYMLELNASDERGINVIREKVKEFARSRTPPEIPFKIVLLDEADNMTSDAQQA 144
Query: 631 LRRTMEMFSSNVRFIL 646
LRR ME++SS RFIL
Sbjct: 145 LRRLMELYSSVTRFIL 160
Score = 80.4 bits (195), Expect = 1e-13
Identities = 88/295 (29%), Positives = 136/295 (45%), Gaps = 43/295 (14%)
Query: 12 VLEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLTGDAKVIA 71
VLE WVEKYRP+ L++IV Q+H+V+RLK +VK +MPHLLFAGPPG GK T A +A
Sbjct: 25 VLEMLWVEKYRPRSLDDIVDQKHVVERLKQFVKQRNMPHLLFAGPPGTGK--TTAAHALA 82
Query: 72 NGELTTIGELVERISNGKLGPTPVRGLTVL--GIDEDGKL---VELPVEYVYKDK----T 122
+ GE + +L + RG+ V+ + E + E+P + V D+ T
Sbjct: 83 H---DLFGENYRQYML-ELNASDERGINVIREKVKEFARSRTPPEIPFKIVLLDEADNMT 138
Query: 123 SELVKIRTRLGRELKVTPYHPLLVNRRNGKIEWVKAEELKPGDRLAIPSFLPAMLNDNPL 182
S+ + RL L+ N + I+ +++ R A F P L+ +
Sbjct: 139 SDAQQALRRLMELYSSVTRFILIANYPSKIIDPIQS-------RCAFFRFQP--LSKQDV 189
Query: 183 AEWLGYFFGNGYTDSEER---VVFESKSKELRKRFMELTRKLFQDAEIKEDSGKVYVSSS 239
E L Y N D EE ++E ++RK L + GKV V +
Sbjct: 190 IERLRYIAENEGVDYEEEALDAIYEISEGDMRKAINVLQAASY--------LGKVTVDA- 240
Query: 240 EVKRLVKSLNKDSIPEQAWKGLRSFLRAYFDCNAEIKDKIIV--STAGKEIAEQI 292
V R+V P + + L + L+ F + KI++ +G+++A QI
Sbjct: 241 -VYRVVGMAK----PREVREMLATALKGDFTAARSLLRKIMIEYGMSGEDVARQI 290
>gb|AAG20394.1| (AE005112) replication factor C small subunit; RfcA [Halobacterium
sp. NRC-1]
Length = 322
Score = 191 bits (480), Expect = 5e-47
Identities = 94/187 (50%), Positives = 131/187 (69%)
Query: 1246 FISNGLVSHNCNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQA 1305
F +N +CNYSSKII+PIQSRCA+FRF L D+ +A LR IAE EGLE T++G+ A
Sbjct: 133 FSNNTRFILSCNYSSKIIDPIQSRCAVFRFAQLGDDAVAAHLREIAETEGLEHTDDGIDA 192
Query: 1306 ILYIAEGDMRRAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKARE 1365
++Y A+GDMRRAIN LQAA+A + +E V+ + + ARPE+I M+ AL G+F AR
Sbjct: 193 LVYAADGDMRRAINALQAASATGDSVNEETVYAITATARPEEIETMVTEALGGDFAAARA 252
Query: 1366 KLREILLKQGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEA 1425
L ++L +GL+G D++ Q+HR V+ ++E V L D++GE ++R+ EGANE +QLEA
Sbjct: 253 TLDDLLTNRGLAGGDIIDQVHRSVWEFDVEEAAAVRLLDRLGEADYRIAEGANERVQLEA 312
Query: 1426 LLAQFTL 1432
LLA L
Sbjct: 313 LLASVAL 319
Score = 125 bits (310), Expect = 4e-27
Identities = 57/94 (60%), Positives = 79/94 (83%), Gaps = 1/94 (1%)
Query: 555 PTVLHNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKI 614
P T +++++A+EL+G++W+ NFLELNASDERGI+V+R+++K+FAR+ GG ++++
Sbjct: 51 PAGTGKTASSVSIAKELYGDDWQDNFLELNASDERGIDVVRDRIKDFARSS-FGGHNYRV 109
Query: 615 IFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
IFLDEADALT DAQ ALRRTME FS+N RFILSC
Sbjct: 110 IFLDEADALTDDAQSALRRTMEQFSNNTRFILSC 143
>emb|CAB57535.1| (Y18930) activator 1, replication factor C, small subunit [Sulfolobus
solfataricus]
Length = 330
Score = 184 bits (463), Expect = 5e-45
Identities = 98/183 (53%), Positives = 132/183 (71%), Gaps = 3/183 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY SKIIEPIQSR A+FRF PL ED+ RL YIA+NE E ++ L+ I I GDMR
Sbjct: 142 CNYLSKIIEPIQSRTALFRFYPLKKEDVVNRLIYIAKNEKAEYDQKALETIYDITMGDMR 201
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
++INILQAA+A KI+ E VF V A+P+++REM+ LAL+G F +AR+KLR +L+ G
Sbjct: 202 KSINILQAASAYG-KISVEAVFKVLGLAQPKEVREMINLALQGKFTQARDKLRTLLITYG 260
Query: 1376 LSGEDVLVQMHREVFN--LPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLI 1433
LSGED++ Q+HRE+ + + I E ++V L D IGE FR++EGA++ IQL ALLA+ +
Sbjct: 261 LSGEDIVKQIHREITSSEIQISEELRVLLLDYIGETEFRIIEGADDEIQLSALLAKMAIY 320
Query: 1434 GKK 1436
G K
Sbjct: 321 GNK 323
Score = 121 bits (301), Expect = 5e-26
Identities = 70/137 (51%), Positives = 89/137 (64%), Gaps = 9/137 (6%)
Query: 520 ELLWDEIIEVEKLKGDFVIYDLHVPKYHNFIGG-NLPTVLH-------NTTAALALAREL 571
E+LW E + L D V + + F+ N+P +L TTAALAL +L
Sbjct: 7 EILWAEKYRPKTLD-DIVNQREIIDRLKKFVKEKNMPHLLFAGPPGTGKTTAALALVHDL 65
Query: 572 FGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQAL 631
+G+N+ FLELNASDERGI+VIR KVKEFART G FK++ LDEAD +T DAQQAL
Sbjct: 66 YGDNYTEYFLELNASDERGIDVIRNKVKEFARTVIPGDIPFKVVLLDEADNMTADAQQAL 125
Query: 632 RRTMEMFSSNVRFILSC 648
RRTME+++ N RFIL+C
Sbjct: 126 RRTMELYTENTRFILAC 142
>gb|AAK41065.1| Activator 1, replication factor C, small subunit (rfc) [Sulfolobus
solfataricus]
Length = 330
Score = 184 bits (463), Expect = 5e-45
Identities = 98/183 (53%), Positives = 132/183 (71%), Gaps = 3/183 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY SKIIEPIQSR A+FRF PL ED+ RL YIA+NE E ++ L+ I I GDMR
Sbjct: 142 CNYLSKIIEPIQSRTALFRFYPLKKEDVVNRLIYIAKNEKAEYDQKALETIYDITMGDMR 201
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
++INILQAA+A KI+ E VF V A+P+++REM+ LAL+G F +AR+KLR +L+ G
Sbjct: 202 KSINILQAASAYG-KISVEAVFKVLGLAQPKEVREMINLALQGKFTQARDKLRTLLITYG 260
Query: 1376 LSGEDVLVQMHREVFN--LPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLI 1433
LSGED++ Q+HRE+ + + I E ++V L D IGE FR++EGA++ IQL ALLA+ +
Sbjct: 261 LSGEDIVKQIHREITSSEIQISEELRVLLLDYIGETEFRIIEGADDEIQLSALLAKMAIY 320
Query: 1434 GKK 1436
G K
Sbjct: 321 GNK 323
Score = 121 bits (301), Expect = 5e-26
Identities = 70/137 (51%), Positives = 89/137 (64%), Gaps = 9/137 (6%)
Query: 520 ELLWDEIIEVEKLKGDFVIYDLHVPKYHNFIGG-NLPTVLH-------NTTAALALAREL 571
E+LW E + L D V + + F+ N+P +L TTAALAL +L
Sbjct: 7 EILWAEKYRPKTLD-DIVNQREIIDRLKKFVKEKNMPHLLFAGPPGTGKTTAALALVHDL 65
Query: 572 FGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQAL 631
+G+N+ FLELNASDERGI+VIR KVKEFART G FK++ LDEAD +T DAQQAL
Sbjct: 66 YGDNYTEYFLELNASDERGIDVIRNKVKEFARTVIPGDIPFKVVLLDEADNMTADAQQAL 125
Query: 632 RRTMEMFSSNVRFILSC 648
RRTME+++ N RFIL+C
Sbjct: 126 RRTMELYTENTRFILAC 142
>sp|Q58095|Y682_METJA HYPOTHETICAL PROTEIN MJ0682 >gi|2129103|pir||B64385 malT-glpR
intergenic region hypothetical intein-containing protein
homolog MJ0682 - Methanococcus jannaschii
>gi|1591397|gb|AAB98677.1| (U67515) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 968
Score = 163 bits (409), Expect = 1e-38
Identities = 124/371 (33%), Positives = 190/371 (50%), Gaps = 33/371 (8%)
Query: 916 RILKEVKEKWLV--RYDDEKAGILARVVGFILGDGHLAR-NGR-----IWFNSSKEELEM 967
+I+K +K++ L+ R D++ GI+AR++GF GDG + + NG + F +E L
Sbjct: 219 QIIKYLKDRGLLPLRMDNKNIGIIARLLGFAFGDGSIVKENGDRERLYVAFYGKRETLIK 278
Query: 968 LANDLRKLGLKPSEIIERDSSSEIQGRKVKGRIYM-------LYVDNAAFHALLRFWKVE 1020
+ DL KLG+K S I R EI R G Y + + + AF + +
Sbjct: 279 IREDLEKLGIKASRIYSRKREVEI--RNAYGDEYTSLCEDNSIKITSKAFALFMHKLGMP 336
Query: 1021 VGNKTKKGYTVPEWIKKGNLFVKREFLRGLFGADGTKPCGKRYNFNGIKLEIRAKKESLE 1080
+G KT++ Y +PEWIKK +VKR FL GLFGADG++ K Y I L + +E E
Sbjct: 337 IGKKTEQIYKIPEWIKKAPKWVKRNFLAGLFGADGSRAVFKNYTPLPINLTMSKSEELKE 396
Query: 1081 RTVEFLNDVADLLREFDVDSKITVSPTKEGFIIRLIVTPNDANYLNFLTRVGYAYA--KD 1138
+EFLN++ LL EFD++S I + +G + + + + NFL R+ Y Y+ K
Sbjct: 397 NILEFLNEIKLLLAEFDIESMIYEIKSLDGRVSYRLAIVGEESIKNFLGRINYEYSGEKK 456
Query: 1139 TYARLVGEYIRIKLAYKNIILPGIAE-KAIELATVTNSTYAAKVLGVSRDFVVNR----- 1192
L EY+R K K I I K + VT S K+ +F+ R
Sbjct: 457 VIGLLAYEYLRRKDIAKEIRKKCIKRAKELYKKGVTVSE-MLKMDEFRNEFISKRLIERA 515
Query: 1193 ----LKGTQIGITRDFMTFEEFM-KERVLNGYVIEKVIKKEKLGY-LDVYDV-TCARDHS 1245
L + I+ F FEEF+ K V+ G+VI+K+ + E++ Y +YDV +++H+
Sbjct: 516 VYENLDEDDVRISTKFPKFEEFIEKYGVIGGFVIDKIKEIEEISYDSKLYDVGIVSKEHN 575
Query: 1246 FISNGLVSHNC 1256
FI+N +V HNC
Sbjct: 576 FIANSIVVHNC 586
>pir||A64430 DNA-directed RNA polymerase (EC 2.7.7.6) subunit A'
(intein-containing) - Methanococcus jannaschii
Length = 1345
Score = 161 bits (403), Expect = 5e-38
Identities = 116/387 (29%), Positives = 198/387 (50%), Gaps = 54/387 (13%)
Query: 888 ILEEEFGIKISYTTVKKLLSGNVDGMAYRILKEVKEKWLV--RYDDEKAGILARVVGFIL 945
+ E++ + + +KK+++ +I+ E+K++ L+ Y+D+KA ILAR+VG ++
Sbjct: 566 MFEDDNRVIVDEEKIKKVINNIGGTYKNKIINELKDRKLIPLTYNDQKASILARIVGHVM 625
Query: 946 GDGHLA---RNGRIWFNSSKEELEMLANDLRKLGLKPSEIIERDSSSEI---QGRK--VK 997
GDG L +N R+ F E+L+ + DL++LG EI + +EI G+K +K
Sbjct: 626 GDGSLIINNKNSRVVFRGDIEDLKTIKEDLKELGYDGEEIKLHEGETEITDYNGKKRIIK 685
Query: 998 GRIYMLYVDNAAFHALLRFWKVEVGNKTKKGYTVPEWIKKGNLFVKREFLRGLFGADGTK 1057
G+ Y V + LL+ G+KTKK Y +P WIK ++K+EFL FG++ T
Sbjct: 686 GKGYSFEVRKKSLCILLKALGCVGGDKTKKMYGIPNWIKTAPKYIKKEFLSAYFGSELTT 745
Query: 1058 PCGKRYNFNGIKLEIR-AKKESLERTVEFLNDVADLLREFDVDSKITVSP---TKEGFII 1113
P + + + +L + AK E + F+ D+ ++L+EF ++ K+ V K+G+
Sbjct: 746 PKIRNHGTSFKELSFKIAKIEEIFDEDRFIKDIKEMLKEFGIELKVRVEEGNLRKDGYKT 805
Query: 1114 RLIVTPNDANYLNFLTRVGYAYA--KDTYARLVGEYIRIKLAYKNIILPGIAEKAIELAT 1171
++ V + N+ F R+GY YA K+T AR EY+ K Y K +
Sbjct: 806 KVYVA-SIYNHKEFFGRIGYTYANKKETLARYAYEYLLTKEKYL---------KDRNIKK 855
Query: 1172 VTNSTYAAKVLGVSRDFVVNRLKGTQIGITRDFMTFEEFMKERVL-NGYVIEKVIKKEKL 1230
+ N+T F+TF++F+KE+ L NG+V EK++ E+
Sbjct: 856 LENNT--------------------------KFITFDKFIKEKCLKNGFVKEKIVSIEET 889
Query: 1231 GYLDVYDV-TCARDHSFISNGLVSHNC 1256
VYD+ T + H+FI+NG ++ NC
Sbjct: 890 KVDYVYDITTISETHNFIANGFLTGNC 916
>sp|Q58445|RPA1_METJA DNA-DIRECTED RNA POLYMERASE SUBUNIT A' >gi|2826359|gb|AAB99046.1|
(U67547) DNA-directed RNA polymerase, subunit A' (rpoA1)
[Methanococcus jannaschii]
Length = 1341
Score = 161 bits (403), Expect = 5e-38
Identities = 116/387 (29%), Positives = 198/387 (50%), Gaps = 54/387 (13%)
Query: 888 ILEEEFGIKISYTTVKKLLSGNVDGMAYRILKEVKEKWLV--RYDDEKAGILARVVGFIL 945
+ E++ + + +KK+++ +I+ E+K++ L+ Y+D+KA ILAR+VG ++
Sbjct: 562 MFEDDNRVIVDEEKIKKVINNIGGTYKNKIINELKDRKLIPLTYNDQKASILARIVGHVM 621
Query: 946 GDGHLA---RNGRIWFNSSKEELEMLANDLRKLGLKPSEIIERDSSSEI---QGRK--VK 997
GDG L +N R+ F E+L+ + DL++LG EI + +EI G+K +K
Sbjct: 622 GDGSLIINNKNSRVVFRGDIEDLKTIKEDLKELGYDGEEIKLHEGETEITDYNGKKRIIK 681
Query: 998 GRIYMLYVDNAAFHALLRFWKVEVGNKTKKGYTVPEWIKKGNLFVKREFLRGLFGADGTK 1057
G+ Y V + LL+ G+KTKK Y +P WIK ++K+EFL FG++ T
Sbjct: 682 GKGYSFEVRKKSLCILLKALGCVGGDKTKKMYGIPNWIKTAPKYIKKEFLSAYFGSELTT 741
Query: 1058 PCGKRYNFNGIKLEIR-AKKESLERTVEFLNDVADLLREFDVDSKITVSP---TKEGFII 1113
P + + + +L + AK E + F+ D+ ++L+EF ++ K+ V K+G+
Sbjct: 742 PKIRNHGTSFKELSFKIAKIEEIFDEDRFIKDIKEMLKEFGIELKVRVEEGNLRKDGYKT 801
Query: 1114 RLIVTPNDANYLNFLTRVGYAYA--KDTYARLVGEYIRIKLAYKNIILPGIAEKAIELAT 1171
++ V + N+ F R+GY YA K+T AR EY+ K Y K +
Sbjct: 802 KVYVA-SIYNHKEFFGRIGYTYANKKETLARYAYEYLLTKEKYL---------KDRNIKK 851
Query: 1172 VTNSTYAAKVLGVSRDFVVNRLKGTQIGITRDFMTFEEFMKERVL-NGYVIEKVIKKEKL 1230
+ N+T F+TF++F+KE+ L NG+V EK++ E+
Sbjct: 852 LENNT--------------------------KFITFDKFIKEKCLKNGFVKEKIVSIEET 885
Query: 1231 GYLDVYDV-TCARDHSFISNGLVSHNC 1256
VYD+ T + H+FI+NG ++ NC
Sbjct: 886 KVDYVYDITTISETHNFIANGFLTGNC 912
>emb|CAC12618.1| (AL445067) probable replication factor C, 40 KD subunit [Thermoplasma
acidophilum]
Length = 330
Score = 147 bits (368), Expect = 7e-34
Identities = 75/182 (41%), Positives = 121/182 (66%), Gaps = 1/182 (0%)
Query: 1255 NCNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDM 1314
+CNYSSKII PIQSR + RFRP+ DE I+++L+ IA+NEG ++ EE + A++ ++ GDM
Sbjct: 148 SCNYSSKIIPPIQSRTVVMRFRPVPDEYISRKLQEIAKNEGFQIDEESMHALVEVSAGDM 207
Query: 1315 RRAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQ 1374
R+AIN+LQA +I+ + ++ + A PE I++M+ A+ G F +ARE + +L+
Sbjct: 208 RKAINVLQAVYT-SGEISPKKIYEIIGYASPEKIQKMISRAINGLFDEAREIVDGMLIYD 266
Query: 1375 GLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLIG 1434
GLSG D++ +H V + I K+ + + + FR+VEG+N+ IQL+AL+A+ IG
Sbjct: 267 GLSGIDIVRSLHSYVRSSMISPKQKIEIIKALADAEFRIVEGSNDRIQLDALIAKLAEIG 326
Query: 1435 KK 1436
+
Sbjct: 327 SR 328
Score = 115 bits (284), Expect = 5e-24
Identities = 64/147 (43%), Positives = 91/147 (61%), Gaps = 7/147 (4%)
Query: 522 LWDEIIEVEKLKGDFVIYDLHVPKYHNFIGGNLPTVLHNTTAALALARELFGENWRHNFL 581
++ E ++KLK + +P H G++ T T+ A+ALA ELFG++W+ N +
Sbjct: 29 IYGEDENIQKLKS--FVEKKEIP--HLLFAGSVGT--GKTSTAIALAIELFGDSWKENMV 82
Query: 582 ELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSN 641
E+NAS+E GI+VIR K+K+ AR KP FKI+FLDEAD LT +AQ ALRRTME++S
Sbjct: 83 EMNASNENGIDVIRNKIKDIARIKPSNPLGFKILFLDEADQLTAEAQAALRRTMEIYSET 142
Query: 642 VRFILSCVTGDTKVYTPDEREVKIRDF 668
RFI SC +K+ P + + F
Sbjct: 143 TRFIFSC-NYSSKIIPPIQSRTVVMRF 168
>pir||C75175 hypothetical protein PAB0383 - Pyrococcus abyssi (strain Orsay)
>gi|5457992|emb|CAB49482.1| (AJ248284) hypothetical
protein [Pyrococcus abyssi]
Length = 916
Score = 145 bits (362), Expect = 4e-33
Identities = 111/352 (31%), Positives = 162/352 (45%), Gaps = 50/352 (14%)
Query: 916 RILKEVKEKWLV--RYDDEKAGILARVVGFILGDGHLARNG---RIWFNSSKEELEMLAN 970
++L ++EK LV R+DD + G +AR++GF GDG+L G + F +E L L
Sbjct: 222 QVLSFLREKGLVPLRWDDPRIGTIARILGFAFGDGYLGEMGGRLTLTFYGKEETLRELKK 281
Query: 971 DLRKLGLKPSEIIERDSSSEIQGRKVKGRIYMLYVDNAAFHALLRFWKVEVGNKTKKGYT 1030
DL +LG+ + + + + K L V + +F L + G KT+K Y
Sbjct: 282 DLERLGISANLYVRESIETTSGHSEGKSLSIELRVTSRSFALFLEKLGMPRGKKTEKAYR 341
Query: 1031 VPEWIKKGNLFVKREFLRGLFGADGTKPCGKRYNFNGIKLEIRAKKESLERTVEFLNDVA 1090
VP WI + L+VKR FL GLF ADG+ K I L E E VEFL DVA
Sbjct: 342 VPGWILEAPLWVKRNFLAGLFAADGSIVEFKGNTPLPINLTQSKSDELAENLVEFLGDVA 401
Query: 1091 DLLREFDVDSKITVSPTKEGFIIRLIVTPNDANYLNFLTRVGYAY--AKDTYARLVGEYI 1148
LL EF +++ + +K+G RL + D + F+ R+ Y Y K + Y+
Sbjct: 402 KLLAEFGIETTLYEVKSKKGVTYRLSIVGED-SIRTFVERINYEYDPEKKVKGLIAAAYL 460
Query: 1149 RIKLAYKNIILPGIAEKAIELATVTNSTYAAKVLGVSRDFVVNRLKGTQIGITRDFMTFE 1208
++K E+ + K + DF TFE
Sbjct: 461 KLK------------ERIV--------------------------KEAHEAVKDDFPTFE 482
Query: 1209 EFMKER-VLNGYVIEKVIKKEKL--GYLDVYDVTCARD-HSFISNGLVSHNC 1256
EF KER G+V EKV+K E++ Y YD+ + H+FI+NG+V HNC
Sbjct: 483 EFAKERGYEGGFVAEKVVKVERVKPEYTKFYDIGVYHEAHNFIANGIVVHNC 534
>gi|6677723 replication factor C (activator 1) 5 (36.5kD) [Homo sapiens]
>gi|728777|sp|P40937|AC11_HUMAN ACTIVATOR 1 36 KDA
SUBUNIT (REPLICATION FACTOR C 36 KDA SUBUNIT) (A1 36 KDA
SUBUNIT) (RF-C 36 KDA SUBUNIT) (RFC36)
>gi|1498257|gb|AAB09784.1| (L07540) replication factor C,
36-kDa subunit [Homo sapiens]
Length = 340
Score = 127 bits (315), Expect = 1e-27
Identities = 63/175 (36%), Positives = 103/175 (58%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY SKII +QSRC FRF PL E + RL ++ E E ++++E+G++A++ ++ GDMR
Sbjct: 155 CNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMR 214
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
RA+NILQ+ K+T+E V+ DI ++ L +F A + E+ +G
Sbjct: 215 RALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRNITELKTLKG 274
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQF 1430
L+ D+L ++H V + ++++L K+ + +RL G NE IQL +L+A F
Sbjct: 275 LALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAF 329
Score = 87.4 bits (213), Expect = 1e-15
Identities = 45/89 (50%), Positives = 61/89 (67%), Gaps = 1/89 (1%)
Query: 561 TTAALALARELFGEN-WRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDE 619
T+ LA A++L+ + + LELNASD+RGI++IR + FA T+ I FK++ LDE
Sbjct: 67 TSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDE 126
Query: 620 ADALTQDAQQALRRTMEMFSSNVRFILSC 648
ADA+TQDAQ ALRR +E F+ N RF L C
Sbjct: 127 ADAMTQDAQNALRRVIEKFTENTRFCLIC 155
>sp|P53034|AC14_DROME ACTIVATOR 1 40 KDA SUBUNIT (REPLICATION FACTOR C 40 KDA SUBUNIT) (A1
40 KDA SUBUNIT) (RF-C 40 KDA SUBUNIT) (RFC40)
>gi|2133712|pir||S55020 replication factor C 40K chain
homolog - fruit fly (Drosophila melanogaster)
>gi|639708|gb|AAB60241.1| (U15967) rfc40 [Drosophila
melanogaster] >gi|7292439|gb|AAF47843.1| (AE003480) RfC40
gene product [Drosophila melanogaster]
Length = 331
Score = 126 bits (314), Expect = 1e-27
Identities = 72/181 (39%), Positives = 109/181 (59%), Gaps = 1/181 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S KIIEPIQSRCA+ RF L+D + +L +A+ E L TE+GL+AI++ A+GDMR
Sbjct: 151 CNTSEKIIEPIQSRCAMLRFTKLSDAQVLAKLIEVAKWEKLNYTEDGLEAIVFTAQGDMR 210
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+ +N LQ+ A IT ENVF V P+ + EM+ + KA + L + L K G
Sbjct: 211 QGLNNLQSTAQGFGDITAENVFKVCDEPHPKLLEEMIHHCAANDIHKAYKILAK-LWKLG 269
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLIGK 1435
S ED++ + R + IDE +K+ +IG + ++++G N ++QL ALLA+ + +
Sbjct: 270 YSPEDIIANIFRVCKRINIDEHLKLDFIREIGITHMKIIDGINSLLQLTALLAKLCIAAE 329
Query: 1436 K 1436
K
Sbjct: 330 K 330
Score = 97.1 bits (238), Expect = 1e-18
Identities = 54/115 (46%), Positives = 75/115 (64%), Gaps = 9/115 (7%)
Query: 552 GNLPTVL-------HNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
GN P ++ TT LAR L G++++ LELNAS+ERGI+V+R K+K FA+
Sbjct: 47 GNAPNIIIAGPPGVGKTTTIQCLARILLGDSYKEAVLELNASNERGIDVVRNKIKMFAQQ 106
Query: 605 K-PIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTP 658
K + KI+ LDEAD++T+ AQQALRRTME++SS RF L+C T + K+ P
Sbjct: 107 KVTLPRGRHKIVILDEADSMTEGAQQALRRTMEIYSSTTRFALACNTSE-KIIEP 160
>gi|6324478 Subunit 4 of Replication Factor C; homologous to human RFC 40 kDa
subunit; Rfc4p [Saccharomyces cerevisiae]
>gi|730503|sp|P40339|RFC4_YEAST ACTIVATOR 1 37 KD SUBUNIT
(REPLICATION FACTOR C 37 KD SUBUNIT)
>gi|626874|pir||A53845 replication factor C chain RFC4
[validated] - yeast (Saccharomyces cerevisiae)
>gi|499704|gb|AAA34970.1| (L20502) 37 kDa subunit
[Saccharomyces cerevisiae] >gi|600464|emb|CAA58185.1|
(X83121) orf 00923 [Saccharomyces cerevisiae]
>gi|841468|gb|AAC49063.1| (U26030) Rfc4p [Saccharomyces
cerevisiae] >gi|1419942|emb|CAA99106.1| (Z74836) ORF
YOL094c [Saccharomyces cerevisiae]
Length = 323
Score = 122 bits (304), Expect = 2e-26
Identities = 69/182 (37%), Positives = 110/182 (59%), Gaps = 4/182 (2%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S+KIIEP+QSRCAI R+ L+DED+ KRL I + E ++ T +GL+AI++ AEGDMR
Sbjct: 144 CNQSNKIIEPLQSRCAILRYSKLSDEDVLKRLLQIIKLEDVKYTNDGLEAIIFTAEGDMR 203
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+AIN LQ+ A + +NVF + P +++M+L + N + + LR L K+G
Sbjct: 204 QAINNLQSTVAGHGLVNADNVFKIVDSPHPLIVKKMLLAS---NLEDSIQILRTDLWKKG 260
Query: 1376 LSGEDVLVQMHREVFNL-PIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLIG 1434
S D++ R NL + E +++ + +IG + R++EG +QL ++LA+ +
Sbjct: 261 YSSIDIVTTSFRVTKNLAQVKESVRLEMIKEIGLTHMRILEGVGTYLQLASMLAKIHKLN 320
Query: 1435 KK 1436
K
Sbjct: 321 NK 322
Score = 92.8 bits (227), Expect = 2e-17
Identities = 52/137 (37%), Positives = 81/137 (58%), Gaps = 9/137 (6%)
Query: 552 GNLPTVLHN-------TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
GN+P ++ + TT+ LA EL G ++ LELNASD+RGI+V+R ++K FA+
Sbjct: 40 GNMPHMIISGMPGIGKTTSVHCLAHELLGRSYADGVLELNASDDRGIDVVRNQIKHFAQK 99
Query: 605 K-PIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDEREV 663
K + KI+ LDEAD++T AQQALRRTME++S++ RF +C K+ P +
Sbjct: 100 KLHLPPGKHKIVILDEADSMTAGAQQALRRTMELYSNSTRFAFAC-NQSNKIIEPLQSRC 158
Query: 664 KIRDFMNYFENGLIKEV 680
I + + ++K +
Sbjct: 159 AILRYSKLSDEDVLKRL 175
>dbj|BAB03291.1| (AB037375) replication factor C small subunit precursor
[Pyrococcus furiosus]
Length = 59
Score = 118 bits (293), Expect = 4e-25
Identities = 53/57 (92%), Positives = 57/57 (99%)
Query: 5 EEVREVKVLEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGK 61
EE+REVKVLEKPWVEKYRPQ+L++IVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGK
Sbjct: 3 EEIREVKVLEKPWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGK 59
>sp|P53033|AC14_CHICK ACTIVATOR 1 40 KD SUBUNIT (REPLICATION FACTOR C 40 KD SUBUNIT) (A1 40
KD SUBUNIT) (RF-C 40 KD SUBUNIT) (RFC40)
>gi|2134397|pir||I50704 replication factor C/activator 1
subunit - chicken >gi|527669|gb|AAA20552.1| (U12438)
replication factor C/activator 1 subunit [Gallus gallus]
Length = 359
Score = 117 bits (291), Expect = 7e-25
Identities = 67/174 (38%), Positives = 100/174 (56%), Gaps = 1/174 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S KIIEPIQSRCA+ R+ L D I RL I E E + T++GL+AI++ A+GDMR
Sbjct: 176 CNASDKIIEPIQSRCAVLRYTKLTDSQILARLLKIVEKEDVPYTDDGLEAIIFTAQGDMR 235
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+N LQ+ + I ENVF V P ++EM+ + N +A K+ L + G
Sbjct: 236 QALNNLQSTYSGFGFINSENVFKVCDEPHPLLVKEMIQHCINANIDEA-YKILAHLWRLG 294
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQ 1429
S EDV+ + R + E +K+ +IG + ++ EG N ++Q+ LLA+
Sbjct: 295 YSPEDVIGNIFRVCKTFQMPEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLAR 348
Score = 94.4 bits (231), Expect = 8e-18
Identities = 55/146 (37%), Positives = 84/146 (56%), Gaps = 9/146 (6%)
Query: 552 GNLPTVL-------HNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
GN+P ++ TT+ L LAR L G + LELNAS++RGI+V+R K+K FA+
Sbjct: 72 GNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQ 131
Query: 605 K-PIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDEREV 663
K + KII LDEAD++T AQQALRRTME++S RF L+C D K+ P +
Sbjct: 132 KVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASD-KIIEPIQSRC 190
Query: 664 KIRDFMNYFENGLIKEVSNRIGRDTV 689
+ + ++ ++ + + ++ V
Sbjct: 191 AVLRYTKLTDSQILARLLKIVEKEDV 216
>gb|AAF69583.1|AC019154_2 (AC019154) Replication Factor C [Leishmania major]
Length = 364
Score = 117 bits (290), Expect = 1e-24
Identities = 59/178 (33%), Positives = 100/178 (56%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN+ +KII +QSRC FRF P+ + RLRY+AE EG++ T +GL A ++ GD+R
Sbjct: 168 CNHINKIIPALQSRCTRFRFAPVKKSSMMPRLRYVAEQEGVKYTTDGLAAAFRLSHGDLR 227
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
R +N +QA+A +IT+E+V+ V P D+ ++ L +F + K E ++++G
Sbjct: 228 RCLNTMQASALSANEITEESVYRVTGNPTPADVTAIVSDMLSSDFATSWVKAEESVVQKG 287
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLI 1433
+S D+ ++H + + + + K +L K+ + + GA E L LL F L+
Sbjct: 288 ISMADLTREIHPVMMAMDLPQDCKCFLLMKLSDLEYYAAGGARESAVLGGLLGAFQLV 345
Score = 84.7 bits (206), Expect = 7e-15
Identities = 58/156 (37%), Positives = 80/156 (51%), Gaps = 24/156 (15%)
Query: 517 AQNELLWDEIIEVEKLKGDFVIYDLHVPKYHNFIGGNLPTVL-------HNTTAALALAR 569
A + L W E L+ D+ H GN+P +L TT A A
Sbjct: 13 AASHLPWVEKYRPSTLESVVAHEDILSTLRHLMDSGNMPHLLLYGPPGTGKTTTIKACAY 72
Query: 570 ELFGE-NWRHNFLELNASDERGINVIREKVKEFARTKPI--------------GG--ASF 612
L+G+ R N LE+NASD+RGI+V+R++ +EFA T I GG A F
Sbjct: 73 YLYGKARVRANVLEMNASDDRGIDVVRQQTREFASTSSIFSMMGTGSSTGGGSGGPAAKF 132
Query: 613 KIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
K++ LDEAD ++ DAQ ALRR +E ++ NVRF + C
Sbjct: 133 KLVILDEADQMSHDAQAALRRVIEKYTRNVRFCILC 168
>gi|11177922 replication factor C (activator 1) 2 (40kD) [Mus musculus]
>gi|4972952|gb|AAD34861.1|AF139987_4 (AF139987)
replication factor C, 40kDa subunit [Mus musculus]
>gi|9800515|gb|AAF99332.1|AF289664_3 (AF289664) RFC2 [Mus
musculus]
Length = 349
Score = 116 bits (289), Expect = 1e-24
Identities = 66/174 (37%), Positives = 100/174 (56%), Gaps = 1/174 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S KIIEPIQSRCA+ R+ L D + RL + E E + T++GL+AI++ A+GDMR
Sbjct: 166 CNASDKIIEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMR 225
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+N LQ+ + I ENVF V P ++EM+ + N +A K+ L G
Sbjct: 226 QALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEA-YKILAHLWHLG 284
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQ 1429
S EDV+ + R P+ E +K+ +IG + ++ EG N ++Q+ LLA+
Sbjct: 285 YSPEDVIGNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLAR 338
Score = 96.0 bits (235), Expect = 3e-18
Identities = 57/146 (39%), Positives = 84/146 (57%), Gaps = 9/146 (6%)
Query: 552 GNLPTVL-------HNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
GN+P ++ TT+ L LAR L G + LELNAS++RGI+V+R K+K FA+
Sbjct: 62 GNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQ 121
Query: 605 K-PIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDEREV 663
K + KII LDEAD++T AQQALRRTME++S RF L+C D K+ P +
Sbjct: 122 KVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASD-KIIEPIQSRC 180
Query: 664 KIRDFMNYFENGLIKEVSNRIGRDTV 689
+ + + ++ + N I ++ V
Sbjct: 181 AVLRYTKLTDAQVLTRLMNVIEKEKV 206
>dbj|BAB16439.1| (AB038319) replication factor C 36kDa subunit [Oryza sativa]
Length = 367
Score = 116 bits (288), Expect = 2e-24
Identities = 57/182 (31%), Positives = 111/182 (60%), Gaps = 6/182 (3%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN+ +KII +QSRC FRF PL+ + +RL++I ++EGL++ + GL A++ ++ GDMR
Sbjct: 175 CNHVNKIIPALQSRCTRFRFAPLDGTHVRERLKHIIQSEGLDVDDGGLTALVRLSNGDMR 234
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNF------LKAREKLRE 1369
+A+NILQ+ ++IT+E V+L P+DI ++ L +F + + + +
Sbjct: 235 KALNILQSTHMASKQITEEAVYLCTGNPMPKDIEQIAYWLLNESFSTSFKCILNYQSISD 294
Query: 1370 ILLKQGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQ 1429
+ +++GL+ D++ ++ VF + + +++ L + + + +RL N+ +QL AL++
Sbjct: 295 MKMRKGLALVDIIREVTMFVFKIQMPSDVRIKLINDLADIEYRLSFACNDKLQLGALIST 354
Query: 1430 FT 1431
FT
Sbjct: 355 FT 356
Score = 87.4 bits (213), Expect = 1e-15
Identities = 45/91 (49%), Positives = 67/91 (73%), Gaps = 3/91 (3%)
Query: 561 TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIG-GA--SFKIIFL 617
T+ LA+AR+L+G + + LELNASDERGI+V+R+++++FA + + GA S K++ L
Sbjct: 85 TSTILAVARKLYGSQYGNMILELNASDERGIDVVRQQIQDFASARSLSFGAKQSVKMVLL 144
Query: 618 DEADALTQDAQQALRRTMEMFSSNVRFILSC 648
DEADA+T+DAQ ALRR +E + + RF L C
Sbjct: 145 DEADAMTKDAQFALRRVIEKHTRSTRFALIC 175
>pir||T37746 activator 1 subunit (replication factor subunit) - fission yeast
(Schizosaccharomyces pombe) >gi|4106657|emb|CAA22597.1|
(AL035064) activator 1 subunit (replication factor
subunit) [Schizosaccharomyces pombe]
Length = 342
Score = 115 bits (284), Expect = 5e-24
Identities = 68/175 (38%), Positives = 101/175 (56%), Gaps = 2/175 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S+KIIEPIQSRCAI R+ L D+ + +RL I + E + T++GL A++ AEGDMR
Sbjct: 156 CNQSNKIIEPIQSRCAILRYSRLTDQQVLQRLLNICKAEKVNYTDDGLAALIMTAEGDMR 215
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+N LQ+ A + ENVF VA + P I M+ GN A EKL+ I G
Sbjct: 216 QAVNNLQSTVAGFGLVNGENVFRVADQPSPVAIHAMLTACQSGNIDVALEKLQGI-WDLG 274
Query: 1376 LSGEDVLVQMHREVFNL-PIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQ 1429
S D++ M R V + I E ++ + +IG+ + ++EG ++QL L+ +
Sbjct: 275 FSAVDIVTNMFRVVKTMDSIPEFSRLEMLKEIGQTHMIILEGVQTLLQLSGLVCR 329
Score = 95.6 bits (234), Expect = 4e-18
Identities = 56/139 (40%), Positives = 81/139 (57%), Gaps = 9/139 (6%)
Query: 552 GNLPTV-------LHNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
GN+P + + TT+ L LA L G ++ LELNASDERGI+V+R ++K FA+
Sbjct: 52 GNMPHLVISGMPGIGKTTSILCLAHALLGPAYKEGVLELNASDERGIDVVRNRIKAFAQK 111
Query: 605 KPI-GGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDEREV 663
K I KII LDEAD++T AQQALRRTME++S+ RF L+C K+ P +
Sbjct: 112 KVILPPGRHKIIILDEADSMTAGAQQALRRTMEIYSNTTRFALAC-NQSNKIIEPIQSRC 170
Query: 664 KIRDFMNYFENGLIKEVSN 682
I + + +++ + N
Sbjct: 171 AILRYSRLTDQQVLQRLLN 189
>pir||A42700 replication factor C - human
Length = 353
Score = 114 bits (282), Expect = 8e-24
Identities = 65/174 (37%), Positives = 99/174 (56%), Gaps = 1/174 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S KIIEPIQSRCA+ R+ L D I RL + E E + T++GL+AI++ A+GDMR
Sbjct: 170 CNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMR 229
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+N LQ+ + I ENVF V P ++EM+ + N +A K+ L G
Sbjct: 230 QALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEA-YKILAHLWHLG 288
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQ 1429
S ED++ + R + E +K+ +IG + ++ EG N ++Q+ LLA+
Sbjct: 289 YSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLAR 342
Score = 92.8 bits (227), Expect = 2e-17
Identities = 57/146 (39%), Positives = 84/146 (57%), Gaps = 10/146 (6%)
Query: 552 GNLPTVL-------HNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
GN+P ++ TT+ L LAR L G + LELNAS++RGI+V+R K+K FA+
Sbjct: 67 GNVPNIIIAGPPGTGKTTSILCLARALLGA-LKDAMLELNASNDRGIDVVRNKIKMFAQQ 125
Query: 605 K-PIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDEREV 663
K + KII LDEAD++T AQQALRRTME++S RF L+C D K+ P +
Sbjct: 126 KVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASD-KIIEPIQSRC 184
Query: 664 KIRDFMNYFENGLIKEVSNRIGRDTV 689
+ + + ++ + N I ++ V
Sbjct: 185 AVLRYTKLTDAQILTRLMNVIEKERV 210
>gi|4506487 replication factor C (activator 1) 2 (40kD) [Homo sapiens]
>gi|11421447|ref|XP_004901.1| replication factor C
(activator 1) 2 (40kD) [Homo sapiens]
>gi|2507300|sp|P35250|AC14_HUMAN ACTIVATOR 1 40 KDA
SUBUNIT (REPLICATION FACTOR C 40 KDA SUBUNIT) (A1 40 KDA
SUBUNIT) (RF-C 40 KDA SUBUNIT) (RFC40)
>gi|1590811|gb|AAB09786.1| (M87338) replication factor C,
40-kDa subunit [Homo sapiens] >gi|2914760|gb|AAC04860.1|
(AF045555) replication factor C subunit 2 [Homo sapiens]
Length = 354
Score = 114 bits (282), Expect = 8e-24
Identities = 65/174 (37%), Positives = 99/174 (56%), Gaps = 1/174 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S KIIEPIQSRCA+ R+ L D I RL + E E + T++GL+AI++ A+GDMR
Sbjct: 171 CNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMR 230
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+N LQ+ + I ENVF V P ++EM+ + N +A K+ L G
Sbjct: 231 QALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEA-YKILAHLWHLG 289
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQ 1429
S ED++ + R + E +K+ +IG + ++ EG N ++Q+ LLA+
Sbjct: 290 YSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLAR 343
Score = 96.7 bits (237), Expect = 2e-18
Identities = 57/146 (39%), Positives = 84/146 (57%), Gaps = 9/146 (6%)
Query: 552 GNLPTVL-------HNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
GN+P ++ TT+ L LAR L G + LELNAS++RGI+V+R K+K FA+
Sbjct: 67 GNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQ 126
Query: 605 K-PIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTPDEREV 663
K + KII LDEAD++T AQQALRRTME++S RF L+C D K+ P +
Sbjct: 127 KVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASD-KIIEPIQSRC 185
Query: 664 KIRDFMNYFENGLIKEVSNRIGRDTV 689
+ + + ++ + N I ++ V
Sbjct: 186 AVLRYTKLTDAQILTRLMNVIEKERV 211
>gb|AAF21015.1|AF208499_1 (AF208499) replication factor C subunit 2 [Rattus norvegicus]
Length = 216
Score = 113 bits (280), Expect = 1e-23
Identities = 65/174 (37%), Positives = 98/174 (55%), Gaps = 1/174 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S KIIEPIQSRC R+ L D + RL + E E + T++GL+AI++ A+GDMR
Sbjct: 33 CNASDKIIEPIQSRCGWLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMR 92
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+N LQ+ + I ENVF V P ++EM+ + N +A K+ L G
Sbjct: 93 QALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEA-YKILAHLWHLG 151
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQ 1429
S EDV+ + R P+ E +K+ +IG + ++ EG N ++Q+ LLA+
Sbjct: 152 YSPEDVIGNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLAR 205
>gb|AAF52944.1| (AE003628) RfC3 gene product [Drosophila melanogaster]
Length = 297
Score = 113 bits (280), Expect = 1e-23
Identities = 60/176 (34%), Positives = 101/176 (57%), Gaps = 1/176 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY SKII +QSRC FRF PL+ + + RL I E E +++TE+G +A+L +A+GDMR
Sbjct: 111 CNYLSKIIPALQSRCTRFRFAPLSQDQMMPRLEKIIEAEAVQITEDGKRALLTLAKGDMR 170
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREK-LREILLKQ 1374
+ +N+LQ+ + ++NV++ +DI +++ L G+ L+ K + +
Sbjct: 171 KVLNVLQSTVMAFDTVNEDNVYMCVGYPLRQDIEQILKALLSGSSLEDSFKTVESAKYAR 230
Query: 1375 GLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQF 1430
GL+ ED++ ++H V L + + L K+ + RL +G E+ Q AL+A F
Sbjct: 231 GLALEDIITELHLFVMRLELPMSVMNKLIVKLAQIEERLAKGCTEVAQTAALVAAF 286
Score = 87.8 bits (214), Expect = 8e-16
Identities = 44/89 (49%), Positives = 63/89 (70%), Gaps = 1/89 (1%)
Query: 561 TTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDE 619
T+ LA AR+L+ + ++ LELNASD+RGI ++R ++ FA T+ I +FK+I LDE
Sbjct: 23 TSTILACARQLYSPQQFKSMVLELNASDDRGIGIVRGQILNFASTRTIFCDTFKLIILDE 82
Query: 620 ADALTQDAQQALRRTMEMFSSNVRFILSC 648
ADA+T DAQ ALRR +E ++ NVRF + C
Sbjct: 83 ADAMTNDAQNALRRIIEKYTDNVRFCVIC 111
>gb|AAF63387.1|AF247499_1 (AF247499) replication factor C subunit 3 [Drosophila melanogaster]
Length = 332
Score = 113 bits (280), Expect = 1e-23
Identities = 60/176 (34%), Positives = 101/176 (57%), Gaps = 1/176 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY SKII +QSRC FRF PL+ + + RL I E E +++TE+G +A+L +A+GDMR
Sbjct: 146 CNYLSKIIPALQSRCTRFRFAPLSQDQMMPRLEKIIEAEAVQITEDGKRALLTLAKGDMR 205
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREK-LREILLKQ 1374
+ +N+LQ+ + ++NV++ +DI +++ L G+ L+ K + +
Sbjct: 206 KVLNVLQSTVMAFDTVNEDNVYMCVGYPLRQDIEQILKALLSGSSLEDSFKTVESAKYAR 265
Query: 1375 GLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQF 1430
GL+ ED++ ++H V L + + L K+ + RL +G E+ Q AL+A F
Sbjct: 266 GLALEDIITELHLFVMRLELPMSVMNKLIVKLAQIEERLAKGCTEVAQTAALVAAF 321
Score = 87.8 bits (214), Expect = 8e-16
Identities = 44/89 (49%), Positives = 63/89 (70%), Gaps = 1/89 (1%)
Query: 561 TTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDE 619
T+ LA AR+L+ + ++ LELNASD+RGI ++R ++ FA T+ I +FK+I LDE
Sbjct: 58 TSTILACARQLYSPQQFKSMVLELNASDDRGIGIVRGQILNFASTRTIFCDTFKLIILDE 117
Query: 620 ADALTQDAQQALRRTMEMFSSNVRFILSC 648
ADA+T DAQ ALRR +E ++ NVRF + C
Sbjct: 118 ADAMTNDAQNALRRIIEKYTDNVRFCVIC 146
>pir||B71039 hypothetical protein PH1602 - Pyrococcus horikoshii
>gi|3258031|dbj|BAA30714.1| (AP000006) 871aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 871
Score = 112 bits (277), Expect = 3e-23
Identities = 124/458 (27%), Positives = 211/458 (45%), Gaps = 111/458 (24%)
Query: 829 WIPRAELEKKARISRTRLNQILQR---LEKKGYI-ERRIEGRKQFVRKI-RNGKILRNAM 883
W+ E+ +K ++ R R+ I + K ++ ER + ++ +R + +GK++ +
Sbjct: 112 WLKIEEMPEKFKLQRLRVYNIEEGHNDFSKVVFVAEREVGSEEKAIRIVTESGKVIEGSE 171
Query: 884 D-----------IKRILEEEFGIKISYTTV----KK---LLSGNVDGMAYRILKEVKEKW 925
D ++ + E ++ + + V KK L +G +++K ++E+
Sbjct: 172 DHPVLTPEGYVYLRNVKEGDYILVYPFEGVPYEEKKGVILDESAFEGEDPQVVKFLRERN 231
Query: 926 LV--RYDDEKAGILARVVGFILGDGHLARNGRIWFNSSKEELEMLANDLRKLGLKPSEII 983
L+ ++ D K GILAR++GF L +G+++ N + F+ +E L + DL +LG++ + +
Sbjct: 232 LIPLQWKDPKVGILARILGFALANGYISENDNLTFHGKEEVLREVRKDLEELGIE-AIVA 290
Query: 984 ERDSSSEIQGRKVKGRIYMLYVDNAAFHALLRFWKVEVGNKTKKGYTVPEWIKKGNLFVK 1043
E D L V + F LL K+ + + ++PEWI +G L++K
Sbjct: 291 EEDK---------------LKVTSREFAFLLE--KLGMAHD-----SIPEWIIEGPLWIK 328
Query: 1044 REFLRGLFGADGTKPCGKRYNFNG-IKLEIRAKKESLERTVEFLNDVADLLREFDVDSKI 1102
R FL GLFGA+G+ F G + L I +L + E LNDV+ +L F V +KI
Sbjct: 329 RNFLAGLFGANGS-----IVEFKGDVPLPI-----TLTHSRELLNDVSRILEGFKVRAKI 378
Query: 1103 TVSPTKEGFIIRLIVTPNDANYLNFLTRVGYAYAKDTYARLVGEYIRIKLAYKNIILPGI 1162
+ K G +L++ D + NFL R+ Y Y + AR + Y +K +K +
Sbjct: 379 KMG--KNG-SYQLVIEDED-SIRNFLGRINYEYDPEKKARGLIAYAYLK--FKEL----- 427
Query: 1163 AEKAIELATVTNSTYAAKVLGVSRDFVVNRLKGTQIGITRDFMTFEEFMKER-VLNGYVI 1221
+KG + MTFEEF ++R G+V
Sbjct: 428 ------------------------------MKG-------NLMTFEEFARDRGYEGGFVA 450
Query: 1222 EKVI--KKEKLGYLDVYDVTCARD-HSFISNGLVSHNC 1256
EKVI K K Y YD+ H+FI+NG+V HNC
Sbjct: 451 EKVIEVKSVKPEYDKFYDIGVYHSAHNFIANGIVVHNC 488
>pir||G71213 probable H(+)-transporting ATP synthase subunit A - Pyrococcus
horikoshii >gi|3258419|dbj|BAA31102.1| (AP000007) 964aa
long hypothetical H(+)-transporting ATP synthase subunit
A [Pyrococcus horikoshii]
Length = 964
Score = 111 bits (274), Expect = 7e-23
Identities = 112/356 (31%), Positives = 173/356 (48%), Gaps = 64/356 (17%)
Query: 6 EVREVKV-------LEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPG 58
E++E+K+ +++P+ EK P+ + I GQ ++ K G+ GP G
Sbjct: 183 EIKELKMYQRWPVRVKRPYKEKLPPE-VPLITGQR-VIDTFFPQAKGGTAA---IPGPFG 237
Query: 59 VGKCLTGDAKVIANG-ELTTIGELVERISNGKLGPTPVRG----------LTVLGIDEDG 107
GKC+ GD V+ L I EL E++ +GK G V G +TV G +DG
Sbjct: 238 SGKCVDGDTLVLTKEFGLIKIKELYEKL-DGK-GRKIVEGNEEWTELEKPITVYGY-KDG 294
Query: 108 KLVELPVEYVYKDKTSELVKIRTRLGRELKVTPYHPLLVNR--RNGKI-EWVKAEELKPG 164
K+VE+ +VYK +S +V+IRTR GR++KVTP H L R ++G I + V A +KPG
Sbjct: 295 KIVEIKATHVYKGVSSGMVEIRTRTGRKIKVTPIHRLFTGRVTKDGLILKEVMAMHVKPG 354
Query: 165 DRLAIPSFL------------------PAMLNDNPLAEWLGYFFGNGYTDSEERVVFESK 206
DR+A+ + P +LN+ LAE+LGY NG S ++
Sbjct: 355 DRIAVVKKIDGGEYIKLDSSNVGEIKVPEILNEE-LAEFLGYLMANGTLKSGIIEIY-CD 412
Query: 207 SKELRKRFMELTRKLF--QDAEIKEDSGKVYVSSSEVKRLVKSLNKDSIPE----QAWKG 260
+ L +R L+ KLF +++ GK V S K LV L + +PE + WK
Sbjct: 413 DESLLERVNSLSLKLFGVGGRIVQKVDGKALVIQS--KPLVDVLRRLGVPEDKKVENWKV 470
Query: 261 LRSFL-------RAYFDCNAEIKDKIIVSTAGKEIAEQISYALAGLGIVAEVDDKG 309
R L RA+ + + K+++ ++ A +E A ++SY A LGI + G
Sbjct: 471 PRELLLSPSNVVRAFVNAYIKGKEEVEITLASEEGAYELSYLFAKLGIYVTISKSG 526
>gb|AAF18689.1|AC010795_4 (AC010795) replication factor, putative; 74998-73295 [Arabidopsis
thaliana]
Length = 333
Score = 110 bits (273), Expect = 1e-22
Identities = 63/178 (35%), Positives = 102/178 (56%), Gaps = 1/178 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S+KIIEPIQSRCA+ RF L+D+ I RL + E + EGL+AI++ A+GDMR
Sbjct: 150 CNTSAKIIEPIQSRCALVRFSRLSDQQILGRLLVVVAAEKVPYVPEGLEAIIFTADGDMR 209
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+N LQA + + ENVF V + P ++ ++ L+ F A + L++ L G
Sbjct: 210 QALNNLQATFSGFSFVNQENVFKVCDQPHPLHVKNIVRNVLESKFDIACDGLKQ-LYDLG 268
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLI 1433
S D++ + R + N + E +K+ + G + R+ +G +QL LLA+ +++
Sbjct: 269 YSPTDIITTLFRIIKNYDMAEYLKLEFMKETGFAHMRICDGVGSYLQLCGLLAKLSIV 326
Score = 100 bits (246), Expect = 1e-19
Identities = 54/115 (46%), Positives = 78/115 (66%), Gaps = 9/115 (7%)
Query: 552 GNLPTVLHN-------TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
GN+P ++ + TT+ LALA EL G N++ LELNASD+RGI+V+R K+K FA+
Sbjct: 46 GNMPNLILSGPPGTGKTTSILALAHELLGTNYKEAVLELNASDDRGIDVVRNKIKMFAQK 105
Query: 605 K-PIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCVTGDTKVYTP 658
K + K++ LDEAD++T AQQALRRT+E++S++ RF L+C T K+ P
Sbjct: 106 KVTLPPGRHKVVILDEADSMTSGAQQALRRTIEIYSNSTRFALACNT-SAKIIEP 159
>gb|AAG21804.1|AF210454_2 (AF210454) replication factor C subunit 1 [Ectocarpus siliculosus
virus]
Length = 324
Score = 108 bits (268), Expect = 4e-22
Identities = 62/175 (35%), Positives = 103/175 (58%), Gaps = 3/175 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S+KIIEPIQSRCAI RF ++D + R+R + + G+E G+ A+ +A+GD+R
Sbjct: 142 CNNSTKIIEPIQSRCAILRFSKVDDAQLRLRIRQVCDMAGVEYDPGGIGALACVADGDVR 201
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMM-LLALKGNFLKAREKLREILLK- 1373
AIN L + + R++T ENV+ +P I +++ LL KG +++A KLR + +
Sbjct: 202 SAINSLASIVSGFRRLTSENVYRTCRSPQPAKIVDIVDLLRNKGGYVEACRKLRGLCGEG 261
Query: 1374 -QGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALL 1427
+G S D+L + + + + E ++ +A IG R++ GA+ +QL A+L
Sbjct: 262 GEGYSPTDILSSFFKALSVIDVRESQRIEIAKVIGLVQNRVLSGASSYLQLAAML 316
>sp|P34429|AC11_CAEEL PUTATIVE ACTIVATOR 1 36 KD SUBUNIT (REPLICATION FACTOR C 36 KD
SUBUNIT) (A1 36 KD SUBUNIT) (RF-C 36 KD SUBUNIT) (RFC36)
>gi|630627|pir||S44809 F44B9.8 protein - Caenorhabditis
elegans >gi|388588|gb|AAA28028.1| (L23648) homology with
A1 replicative polymerase accessory protein; putative
[Caenorhabditis elegans]
Length = 447
Score = 108 bits (267), Expect = 5e-22
Identities = 58/175 (33%), Positives = 94/175 (53%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY + I+ IQSRC FRF PL+ + I RL YI E E L++T +G A+L +++GDMR
Sbjct: 196 CNYLASIVPAIQSRCTRFRFAPLDQKLIVPRLEYIVETEQLKMTPDGKDALLIVSKGDMR 255
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
IN LQ+ A +++ V+ + P++++E++ L K ++ L + G
Sbjct: 256 TVINTLQSTAMSFDTVSENTVYQCIGQPTPKEMKEVVKTLLNDPSKKCMNTIQTKLFENG 315
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQF 1430
+ +DV+ +H VF L I + + +GE L G + QL A++A F
Sbjct: 316 YALQDVITHLHDFVFTLDIPDEAMSAIITGLGEVEENLSTGCSNETQLAAVVAAF 370
Score = 73.7 bits (178), Expect = 1e-11
Identities = 46/118 (38%), Positives = 63/118 (52%), Gaps = 30/118 (25%)
Query: 561 TTAALALARELFGENWRHNF-LELNASDERGINVIREKVKEFARTKPI---------GGA 610
TT LA AR+++ + LELNASDERGI+V+R + FA+TK + G
Sbjct: 79 TTTVLAAARQMYSPTKMASMVLELNASDERGIDVVRNTIVNFAQTKGLQAFSTSSNTGTV 138
Query: 611 SFKIIFLDEADALTQDAQQALR--------------------RTMEMFSSNVRFILSC 648
FK++ LDEADA+T+DAQ ALR R +E ++ NVRF + C
Sbjct: 139 PFKLVILDEADAMTKDAQNALRRLDKTDYEQNIIIHNVNIYFRVIEKYTDNVRFCIIC 196
>emb|CAA07618.1| (AJ007712) replication factor C subunit [Arxula adeninivorans]
Length = 338
Score = 107 bits (264), Expect = 1e-21
Identities = 61/174 (35%), Positives = 97/174 (55%), Gaps = 3/174 (1%)
Query: 1257 NYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRR 1316
NY+ K+ + SRC FRF PL ++ I RL ++ E E ++L+ E Q++L+++ GDMRR
Sbjct: 152 NYTHKLNPALLSRCTRFRFSPLKEDAIKHRLAHVIEQESVDLSPEAFQSLLHLSSGDMRR 211
Query: 1317 AINILQAA-AALD--RKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLK 1373
A+N+LQA A++D +I++E V+ RP DIR ++ L G++ A I
Sbjct: 212 ALNVLQACYASVDAGEQISEELVYDCVGSPRPADIRTVLQAVLDGSWESALHTFSYIKQS 271
Query: 1374 QGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALL 1427
+GL+ D+L E L + ++ L D + E +RL G NE IQ A +
Sbjct: 272 KGLALADMLTAFAVEFQKLDLQNKTRIALLDGLSEIEWRLSSGGNESIQTSATI 325
Score = 101 bits (248), Expect = 8e-20
Identities = 49/102 (48%), Positives = 74/102 (72%), Gaps = 7/102 (6%)
Query: 552 GNLPTVLHN-------TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
G LP +L + TT +A+AR+++G+N+R+ LELNASDERGI+V+R+++K FA T
Sbjct: 48 GKLPHLLFHGPPGTGKTTTIIAVARQIYGKNYRNMILELNASDERGIDVVRDQIKTFAST 107
Query: 605 KPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFIL 646
+ I + FK++ LDEADA+T AQ ALRR +E +S++ RF +
Sbjct: 108 RQIFSSGFKLVILDEADAMTNAAQNALRRIIEKYSAHTRFCI 149
Score = 71.4 bits (172), Expect = 7e-11
Identities = 31/66 (46%), Positives = 45/66 (67%), Gaps = 5/66 (7%)
Query: 4 MEEVREVKVLEK-----PWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPG 58
M++ ++V+ +EK PWVEKYRP L+E+ G E ++ +K +V+ G +PHLLF GPPG
Sbjct: 1 MDKGKKVETVEKQENSLPWVEKYRPTTLDEVAGHEGVITTIKKFVEEGKLPHLLFHGPPG 60
Query: 59 VGKCLT 64
GK T
Sbjct: 61 TGKTTT 66
>pir||D75028 h+-transporting ATP synthase, chain alpha (atpa) PAB2378 -
Pyrococcus abyssi (strain Orsay)
>gi|5459180|emb|CAB50666.1| (AJ248288) H+-transporting
ATP synthase, subunit Alpha (atpA) [Pyrococcus abyssi]
Length = 1017
Score = 107 bits (264), Expect = 1e-21
Identities = 116/393 (29%), Positives = 186/393 (46%), Gaps = 83/393 (21%)
Query: 6 EVREVKV-------LEKPWVEKYRPQKLEEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPG 58
E++E+K+ +++P+ EK P+ + I GQ ++ K G+ GP G
Sbjct: 183 EIKELKMYQRWPVRVKRPYKEKLPPE-VPLITGQR-VIDTFFPQAKGGTAA---IPGPFG 237
Query: 59 VGKCLTGDAKVIANG-ELTTIGELVERISNGKLGPTPVRG----------LTVLGIDEDG 107
GKC+ GD V+ L I +L +I +GK G V G +T+ G +DG
Sbjct: 238 SGKCVDGDTLVLTKEFGLIKIKDLY-KILDGK-GKKTVNGNEEWTELERPITLYGY-KDG 294
Query: 108 KLVELPVEYVYKDKTSELVKIRTRLGRELKVTPYHPLLVNR--RNG-KIEWVKAEELKPG 164
K+VE+ +VYK ++ +++IRTR GR++KVTP H L R +NG +I V A++LK G
Sbjct: 295 KIVEIKATHVYKGFSAGMIEIRTRTGRKIKVTPIHKLFTGRVTKNGLEIREVMAKDLKKG 354
Query: 165 DRLAIPS----------------------FLPAMLNDNPLAEWLGYFFGNGYTDSEERVV 202
DR+ + +P +L D LAE+LGY +G T V
Sbjct: 355 DRIIVAKKIDGGERVKLNIRVEQKRGKKIRIPDVL-DEKLAEFLGYLIADG-TLKPRTVA 412
Query: 203 FESKSKELRKRFMELTRKLF--QDAEIKEDSGKVYVSSSEVKRLVKSLNKDSIPE----Q 256
+ + L +R EL +LF + +K + K + S K LV+ +K +P +
Sbjct: 413 IYNNDESLLRRANELANELFNIEGKIVKGRTVKALLIHS--KALVEFFSKLGVPRNKKAR 470
Query: 257 AWK-----------GLRSFLRAYFDCNA---EIKDKIIVSTAGKEIAEQISYALAGLGIV 302
WK +++F++AY C+ E K +I + TA +E A SY LA LGI
Sbjct: 471 TWKVPKELLISEPEVVKAFIKAYIMCDGYYDENKGEIEIVTASEEAAYGFSYLLAKLGIY 530
Query: 303 AEVDDK-------GSVIISDPENVSRF-LDEIG 327
A + +K V+IS N+ + ++ +G
Sbjct: 531 AIIREKIIGDKVYYRVVISGESNLEKLGIERVG 563
>gb|AAF07781.1|AC010704_6 (AC010704) putative replication factor C; 24844-22715 [Arabidopsis
thaliana]
Length = 369
Score = 106 bits (263), Expect = 1e-21
Identities = 57/183 (31%), Positives = 109/183 (59%), Gaps = 8/183 (4%)
Query: 1257 NYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRR 1316
N+ +KII +QSRC FRF PL+ +++RL+++ E E L +++ GL A++ ++ GDMR+
Sbjct: 176 NHVNKIIPALQSRCTRFRFAPLDGVHMSQRLKHVIEAERLVVSDCGLAALVRLSNGDMRK 235
Query: 1317 AINILQAAAAL--------DRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLR 1368
A+NILQ+ ++IT+E+V+L P+DI ++ L F + + +
Sbjct: 236 ALNILQSTHMASKEITEEESKQITEEDVYLCTGNPLPKDIEQISHWLLNKPFDECYKDVS 295
Query: 1369 EILLKQGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLA 1428
EI ++GL+ D++ ++ +F + + ++V L + + + +RL G N+ +QL A+++
Sbjct: 296 EIKTRKGLAIVDIVKEITLFIFKIKMPSAVRVQLINDLADIEYRLSFGCNDKLQLGAIIS 355
Query: 1429 QFT 1431
FT
Sbjct: 356 TFT 358
Score = 92.4 bits (226), Expect = 3e-17
Identities = 44/88 (50%), Positives = 69/88 (78%), Gaps = 2/88 (2%)
Query: 561 TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTK--PIGGASFKIIFLD 618
T+ LA+AR+L+G +R+ LELNASD+RGI+V+R+++++FA T+ +G +S K++ LD
Sbjct: 86 TSTILAVARKLYGPKYRNMILELNASDDRGIDVVRQQIQDFASTQSFSLGKSSVKLVLLD 145
Query: 619 EADALTQDAQQALRRTMEMFSSNVRFIL 646
EADA+T+DAQ ALRR +E ++ + RF L
Sbjct: 146 EADAMTKDAQFALRRVIEKYTKSTRFAL 173
>gi|4506491 replication factor C (activator 1) 4 (37kD) [Homo sapiens]
>gi|11435044|ref|XP_003190.1| replication factor C
(activator 1) 4 (37kD) [Homo sapiens]
>gi|1703052|sp|P35249|AC12_HUMAN ACTIVATOR 1 37 KD
SUBUNIT (REPLICATION FACTOR C 37 KD SUBUNIT) (A1 37 KD
SUBUNIT) (RF-C 37 KD SUBUNIT) (RFC37)
>gi|1498256|gb|AAB09785.1| (M87339) replication factor C,
37-kDa subunit [Homo sapiens]
Length = 363
Score = 103 bits (254), Expect = 2e-20
Identities = 58/175 (33%), Positives = 106/175 (60%), Gaps = 3/175 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY S+IIEP+ SRC+ FRF+PL+D+ +RL IA+ E +++++EG+ ++ ++EGD+R
Sbjct: 180 CNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLR 239
Query: 1316 RAINILQAAAAL--DRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLK 1373
+AI LQ+A L ++IT++ + +A E I + G+F K +++ L+
Sbjct: 240 KAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKD-LID 298
Query: 1374 QGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLA 1428
+G + ++ Q+H V + + K + +K+ E + L +GA+E +QL +L A
Sbjct: 299 EGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCA 353
Score = 93.6 bits (229), Expect = 1e-17
Identities = 59/113 (52%), Positives = 68/113 (59%), Gaps = 15/113 (13%)
Query: 551 GGNLPTVLH-------NTTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFA 602
G +LP +L T+ LA ARELFG E +R LELNASDERGI V+REKVK FA
Sbjct: 68 GADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFA 127
Query: 603 RTKPIGGAS-------FKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
+ G S FKI+ LDEAD++T AQ ALRRTME S RF L C
Sbjct: 128 QLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC 180
>dbj|BAB16441.1| (AB045677) replication factor C 37kDa subunit [Oryza sativa]
Length = 339
Score = 103 bits (254), Expect = 2e-20
Identities = 60/169 (35%), Positives = 91/169 (53%), Gaps = 1/169 (0%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY S+IIEP+ SRCA FRF+PL++E ++ R+ +I EGL L + L + I+ GD+R
Sbjct: 151 CNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDAQALATLSTISNGDLR 210
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
RAI LQ+AA L + S A PED+ + +L + K K ++ G
Sbjct: 211 RAITYLQSAARLFGSSISSTDLISVSGAIPEDVVKSLLASCKSGEFDVANKEVNNIIADG 270
Query: 1376 LSGEDVLVQMHREVFNL-PIDEPMKVYLADKIGEYNFRLVEGANEMIQL 1423
++ Q + N I + K + K+GE + LV+GA+E +QL
Sbjct: 271 YPVSQLISQFLDVIVNADDIPDEQKARICKKLGEADKCLVDGADEYLQL 319
Score = 91.7 bits (224), Expect = 5e-17
Identities = 51/97 (52%), Positives = 66/97 (67%), Gaps = 10/97 (10%)
Query: 561 TTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFARTKPIGGAS-------- 611
TT ALA+A +L+G E ++ LELNASD+RGINV+R K+K+FA +G A
Sbjct: 56 TTTALAIAYQLYGPELYKSRVLELNASDDRGINVVRTKIKDFAAVA-VGSARKGGYPCPP 114
Query: 612 FKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
+KII LDEAD++T+DAQ ALRRTME +S RF C
Sbjct: 115 YKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFIC 151
>pir||T43410 replication factor C chain Rfc3 - fission yeast
(Schizosaccharomyces pombe) >gi|4468733|emb|CAB38106.1|
(AJ012839) replication factor C subunit
[Schizosaccharomyces pombe] >gi|5688939|dbj|BAA82745.1|
(AB017039) Rfc3 [Schizosaccharomyces pombe]
>gi|5688941|dbj|BAA82746.1| (AB017040) Rfc3
[Schizosaccharomyces pombe]
Length = 342
Score = 101 bits (248), Expect = 8e-20
Identities = 46/88 (52%), Positives = 67/88 (75%)
Query: 561 TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEA 620
T+ LA AR+++G N+R+ +ELNASD+RGI+ +RE++K FA T+ I ++FK+I LDEA
Sbjct: 70 TSTILACARKIYGPNYRNQLMELNASDDRGIDAVREQIKNFASTRQIFASTFKMIILDEA 129
Query: 621 DALTQDAQQALRRTMEMFSSNVRFILSC 648
DA+T AQ ALRR +E ++ NVRF + C
Sbjct: 130 DAMTLAAQNALRRVIEKYTKNVRFCIIC 157
Score = 100 bits (246), Expect = 1e-19
Identities = 54/173 (31%), Positives = 93/173 (53%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY +KI IQSRC FRF+PL ++I K + ++ ++E + + A+L +++GDMR
Sbjct: 157 CNYINKISPAIQSRCTRFRFQPLPPKEIEKTVDHVIQSEHCNIDPDAKMAVLRLSKGDMR 216
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+NILQA A I ++ P DI + + F+ A + I ++G
Sbjct: 217 KALNILQACHAAYDHIDVSAIYNCVGHPHPSDIDYFLKSIMNDEFVIAFNTISSIKQQKG 276
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLA 1428
L+ +D+L + + L I K+++ D++ R+ G +E IQL A++A
Sbjct: 277 LALQDILTCIFEALDELEIKPNAKIFILDQLATIEHRMSFGCSEKIQLSAMIA 329
>gb|AAB88360.1| (AF036699) strong similarity to the activator 1 36 to 40 KD
subunits family of DNA replication factors
[Caenorhabditis elegans]
Length = 334
Score = 100 bits (247), Expect = 1e-19
Identities = 54/105 (51%), Positives = 72/105 (68%), Gaps = 8/105 (7%)
Query: 552 GNLPTVLHN-------TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
GN+P ++ + TT+ ALAREL G+ + LELNASDERGI+V+R ++K FA+T
Sbjct: 41 GNVPNIVLSGPPGCGKTTSVWALARELLGDKVKEAVLELNASDERGIDVVRHRIKTFAQT 100
Query: 605 K-PIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
K + KII LDEAD++T AQQALRRTMEM++ RF L+C
Sbjct: 101 KVTLPEGRHKIIILDEADSMTDGAQQALRRTMEMYTKTTRFALAC 145
Score = 98.7 bits (242), Expect = 4e-19
Identities = 57/177 (32%), Positives = 96/177 (54%), Gaps = 5/177 (2%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CN S KIIEPIQSRCA+ R+ L+ + R++ +A+ E + + GL+AIL+ A+GDMR
Sbjct: 145 CNQSEKIIEPIQSRCALLRYTKLSPVQLLTRVKEVAKAEKVNYDDGGLEAILFTAQGDMR 204
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+N LQA + ENV V P+ + +M+ F +A + + E + G
Sbjct: 205 QALNNLQATVNAYELVNKENVLKVCDEPHPDLMIKMLHYCTDRKFFEASKIIHE-FHRLG 263
Query: 1376 LSGEDVLVQMHREV----FNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLA 1428
S +D++ + R V + + E +++ +I + R+V+G +QL L+A
Sbjct: 264 FSSDDIVSTLFRVVKTVELSKNVSEQLRMEYIRQIAMCHMRIVQGLTSKLQLSRLIA 320
>pir||T38458 replication factor 3 subunit - fission yeast (Schizosaccharomyces
pombe) (fragment) >gi|4494101|emb|CAB39134.1| (Z98978)
replication factor 3 subunit [Schizosaccharomyces pombe]
Length = 224
Score = 100 bits (246), Expect = 1e-19
Identities = 54/173 (31%), Positives = 93/173 (53%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY +KI IQSRC FRF+PL ++I K + ++ ++E + + A+L +++GDMR
Sbjct: 39 CNYINKISPAIQSRCTRFRFQPLPPKEIEKTVDHVIQSEHCNIDPDAKMAVLRLSKGDMR 98
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
+A+NILQA A I ++ P DI + + F+ A + I ++G
Sbjct: 99 KALNILQACHAAYDHIDVSAIYNCVGHPHPSDIDYFLKSIMNDEFVIAFNTISSIKQQKG 158
Query: 1376 LSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLA 1428
L+ +D+L + + L I K+++ D++ R+ G +E IQL A++A
Sbjct: 159 LALQDILTCIFEALDELEIKPNAKIFILDQLATIEHRMSFGCSEKIQLSAMIA 211
>pir||A45253 activator 1 37K chain - human
Length = 363
Score = 98.7 bits (242), Expect = 4e-19
Identities = 57/175 (32%), Positives = 102/175 (57%), Gaps = 3/175 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY S+IIEP+ SRC+ FRF+PL+D+ +RL IA+ E + ++ G+ ++ ++EGD+R
Sbjct: 180 CNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVPISHRGIAYLVKVSEGDLR 239
Query: 1316 RAINILQAAAAL--DRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLK 1373
+AI LQ+A L ++IT++ + +A E I + G+F K +++ L+
Sbjct: 240 KAITFLQSATRLTGGKEITEKVITHIAGVIPAEKIDGVFAACQSGSFDKLEAVVKD-LID 298
Query: 1374 QGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLA 1428
+G + ++ Q+H V + + K + ++ E + L EGA+E +QL +L A
Sbjct: 299 EGHAATQLVNQLHDVVVENNLSDKQKSIITGELAEVDKCLAEGADEHLQLISLCA 353
Score = 93.6 bits (229), Expect = 1e-17
Identities = 59/113 (52%), Positives = 68/113 (59%), Gaps = 15/113 (13%)
Query: 551 GGNLPTVLH-------NTTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFA 602
G +LP +L T+ LA ARELFG E +R LELNASDERGI V+REKVK FA
Sbjct: 68 GADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFA 127
Query: 603 RTKPIGGAS-------FKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
+ G S FKI+ LDEAD++T AQ ALRRTME S RF L C
Sbjct: 128 QLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC 180
>gb|AAG37985.1|AF069296_1 (AF069296) replication factor C3 [Plasmodium falciparum]
Length = 344
Score = 98.3 bits (241), Expect = 5e-19
Identities = 56/177 (31%), Positives = 92/177 (51%), Gaps = 2/177 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY +KI IQSRC FRF PL E + + IA++E + LTE G+ +++ + GDMR
Sbjct: 151 CNYVNKITPAIQSRCTAFRFAPLKKEYMKNKALDIAKSENVNLTEGGIDSLIRVGHGDMR 210
Query: 1316 RAINILQAAAALDRK-ITDENVFL-VASRARPEDIREMMLLALKGNFLKAREKLREILLK 1373
R +N LQ + + + DENV L P + ++++ KG+ ++ E + +
Sbjct: 211 RILNCLQVVSLSHKNLVIDENVILSTLDIPLPSETKKILEYFTKGSIKESYEFVSNLQYD 270
Query: 1374 QGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQF 1430
+G S +D+++ ++ V + L GE R GA+E I L AL++ F
Sbjct: 271 KGYSTKDIMMCLYESVLTYDFPDSAFCLLLKNFGEIEERCSSGASEQITLSALISAF 327
Score = 85.4 bits (208), Expect = 4e-15
Identities = 45/92 (48%), Positives = 61/92 (65%), Gaps = 4/92 (4%)
Query: 561 TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTK----PIGGASFKIIF 616
T+ LA+ +EL+G+ LELNASD+RGINVIR+++K FA +K + K+I
Sbjct: 60 TSTILAVCKELYGDKRSSFVLELNASDDRGINVIRDQIKTFAESKNHYTTCEKTTLKLII 119
Query: 617 LDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
LDEAD +T AQ A+RR ME ++ NVRF L C
Sbjct: 120 LDEADHMTYPAQNAMRRIMENYAKNVRFCLLC 151
>gi|6324039 Subunit 3 of Replication Factor C; homologous to human RFC 36 kDa
subunit; Rfc3p [Saccharomyces cerevisiae]
>gi|585844|sp|P38629|RFC3_YEAST ACTIVATOR 1 40 KD
SUBUNIT (REPLICATION FACTOR C 40 KD SUBUNIT)
>gi|1078326|pir||A36988 replication factor C chain RFC3
[validated] - yeast (Saccharomyces cerevisiae)
>gi|439118|gb|AAA34969.1| (L18755) replication factor C
[Saccharomyces cerevisiae] >gi|841466|gb|AAC49062.1|
(U26029) Rfc3p [Saccharomyces cerevisiae]
>gi|1050872|gb|AAC49110.1| (U23084) replication factor
C, 40 kDa subunit [Saccharomyces cerevisiae]
>gi|1302375|emb|CAA96207.1| (Z71566) ORF YNL290w
[Saccharomyces cerevisiae]
Length = 340
Score = 97.5 bits (239), Expect = 9e-19
Identities = 49/100 (49%), Positives = 69/100 (69%), Gaps = 7/100 (7%)
Query: 552 GNLPTVLH-------NTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFART 604
G LP +L T+ +ALARE++G+N+ + LELNASD+RGI+V+R ++K+FA T
Sbjct: 44 GKLPHLLFYGPPGTGKTSTIVALAREIYGKNYSNMVLELNASDDRGIDVVRNQIKDFAST 103
Query: 605 KPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRF 644
+ I FK+I LDEADA+T AQ ALRR +E ++ N RF
Sbjct: 104 RQIFSKGFKLIILDEADAMTNAAQNALRRVIERYTKNTRF 143
Score = 84.7 bits (206), Expect = 7e-15
Identities = 49/177 (27%), Positives = 101/177 (56%), Gaps = 6/177 (3%)
Query: 1257 NYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRR 1316
NY+ K+ + SRC FRF+PL E I +R+ + +E L+L+ +A++ ++ GDMRR
Sbjct: 148 NYAHKLTPALLSRCTRFRFQPLPQEAIERRIANVLVHEKLKLSPNAEKALIELSNGDMRR 207
Query: 1317 AINILQAA-AALDR----KITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREIL 1371
+N+LQ+ A LD +I+D+ ++ RP D++ ++ L+ ++ A L ++
Sbjct: 208 VLNVLQSCKATLDNPDEDEISDDVIYECCGAPRPSDLKAVLKSILEDDWGTAHYTLNKVR 267
Query: 1372 LKQGLSGEDVLVQMHREVFNLPI-DEPMKVYLADKIGEYNFRLVEGANEMIQLEALL 1427
+GL+ D++ + + + + + +E +V+L K+ + + + +G N+ IQ A++
Sbjct: 268 SAKGLALIDLIEGIVKILEDYELQNEETRVHLLTKLADIEYSISKGGNDQIQGSAVI 324
>gb|AAF48768.1| (AE003506) CG8142 gene product [Drosophila melanogaster]
Length = 288
Score = 96.7 bits (237), Expect = 2e-18
Identities = 54/171 (31%), Positives = 98/171 (56%), Gaps = 3/171 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY S+II PI SRC+ FRF+ L ++ + RL+YI E EG+++ ++ ++I+ I+ GD+R
Sbjct: 106 CNYVSRIIVPITSRCSKFRFKALGEDKVIDRLKYICEMEGVKIEDDAYKSIVKISGGDLR 165
Query: 1316 RAINILQAAAAL---DRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILL 1372
RAI LQ+ L + I ++F ++ + + + + GN+ + + +REI
Sbjct: 166 RAITTLQSCYRLKGPEHIINTADLFEMSGVIPEYYLEDYLEVCRSGNYERLEQFVREIGF 225
Query: 1373 KQGLSGEDVLVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQL 1423
G+ + + V + +++P K + DK+GE FRL +G +E +Q+
Sbjct: 226 SAYSVGQMMEQFVEFIVHHPGLNDPQKATICDKLGECCFRLQDGGSEYLQI 276
Score = 89.7 bits (219), Expect = 2e-16
Identities = 49/95 (51%), Positives = 64/95 (66%), Gaps = 7/95 (7%)
Query: 561 TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFAR-----TKPIGG--ASFK 613
T+ LA +R++FG+ ++ LELNASDERGINV+R K+K F++ +P G FK
Sbjct: 12 TSTILAASRQIFGDMFKDRILELNASDERGINVVRTKIKNFSQLSASSVRPDGKPCPPFK 71
Query: 614 IIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
II LDEAD++T AQ ALRRTME S + RF L C
Sbjct: 72 IIILDEADSMTHAAQSALRRTMEKESRSTRFCLIC 106
>sp|Q09843|RFC2_SCHPO PROBABLE ACTIVATOR 1 41 KD SUBUNIT (REPLICATION FACTOR C 41 KD
SUBUNIT) >gi|2130334|pir||S62493 replication factor C
activator 1 41 kd subunit - fission yeast
(Schizosaccharomyces pombe) >gi|1039340|emb|CAA91237.1|
(Z64354) replication factor C activator 1 41 kd subunit
[Schizosaccharomyces pombe]
Length = 340
Score = 96.3 bits (236), Expect = 2e-18
Identities = 58/113 (51%), Positives = 70/113 (61%), Gaps = 14/113 (12%)
Query: 550 IGGNLPTVLH-------NTTAALALARELFGEN-WRHNFLELNASDERGINVIREKVKEF 601
+ NLP +L T+ LAL+RELFG + LELNASDERGI++IREKVK F
Sbjct: 48 LSNNLPHMLFYGSPGTGKTSTILALSRELFGPQLMKSRVLELNASDERGISIIREKVKSF 107
Query: 602 ARTKPIGGAS------FKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
A+T FKII LDEAD++TQDAQ ALRRTME ++ RF L C
Sbjct: 108 AKTTVTNKVDGYPCPPFKIIILDEADSMTQDAQAALRRTMESYARITRFCLIC 160
Score = 93.2 bits (228), Expect = 2e-17
Identities = 59/181 (32%), Positives = 104/181 (56%), Gaps = 4/181 (2%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY ++II+P+ SRC+ +RF+PL++E++ KRL +IA ++ + + + A++ + GDMR
Sbjct: 160 CNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMR 219
Query: 1316 RAINILQAAAALDR--KITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLK 1373
+AI LQ+AA L + IT +V +A IR ++ A N + E L +
Sbjct: 220 KAITFLQSAANLHQGTPITISSVEELAGAVPYNIIRSLLDTAYTKN-VSNIETLSRDVAA 278
Query: 1374 QGLSGEDVLVQMHREVF-NLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTL 1432
+G S +L Q+H + + P+K + K+ E + RL +GA+E +QL LL+ ++
Sbjct: 279 EGYSTGIILSQLHDVLLKEETLSSPVKYKIFMKLSEVDKRLNDGADETLQLLDLLSSISV 338
Query: 1433 I 1433
+
Sbjct: 339 V 339
>gb|AAD41422.1|AC007727_11 (AC007727) Similar to gb|M87339 replication factor C, 37-kDa
subunit from Homo sapiens and is a member of PF|00004
ATPases associated with various cellular activities.
[Arabidopsis thaliana]
Length = 319
Score = 95.2 bits (233), Expect = 5e-18
Identities = 53/97 (54%), Positives = 65/97 (66%), Gaps = 9/97 (9%)
Query: 561 TTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFA--------RTKPIGGAS 611
TT ALA+A +LFG E ++ LELNASD+RGINV+R K+K+FA R S
Sbjct: 56 TTTALAIAHQLFGPELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSNHRQSGYPCPS 115
Query: 612 FKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
FKII LDEAD++T+DAQ ALRRTME +S RF C
Sbjct: 116 FKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFIC 152
Score = 84.7 bits (206), Expect = 7e-15
Identities = 53/170 (31%), Positives = 83/170 (48%), Gaps = 22/170 (12%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY S+IIEP+ SRCA FRF+PL++E ++ R+ +I EGL L E L + I++GD+R
Sbjct: 152 CNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDGEALSTLSSISQGDLR 211
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
RAI LQ P ++ + A K K + ++ +G
Sbjct: 212 RAITYLQVV--------------------PLEVVNKLFTACKSGDFDIANKEVDNIVAEG 251
Query: 1376 LSGEDVLVQMHREVFNLPID--EPMKVYLADKIGEYNFRLVEGANEMIQL 1423
++ Q+ V D + K + + E + RLV+GA+E +QL
Sbjct: 252 YPASQIINQLFDIVAEADSDITDMQKAKICKCLAETDKRLVDGADEYLQL 301
>gi|6322528 Subunit 2 of Replication Factor C; homologous to human RFC 37 kDa
subunit; Rfc2p [Saccharomyces cerevisiae]
>gi|730502|sp|P40348|RFC2_YEAST ACTIVATOR 1 41 KD
SUBUNIT (REPLICATION FACTOR C 41 KD SUBUNIT)
>gi|626873|pir||S45531 replication factor C chain RFC2 -
yeast (Saccharomyces cerevisiae)
>gi|498463|dbj|BAA05858.1| (D28499) Rfc2 protein
[Saccharomyces cerevisiae] >gi|841464|gb|AAC49061.1|
(U26028) Rfc2p [Saccharomyces cerevisiae]
>gi|1015747|emb|CAA89596.1| (Z49568) ORF YJR068w
[Saccharomyces cerevisiae] >gi|1019690|gb|AAB39294.1|
(L47993) ORF YJR068w [Saccharomyces cerevisiae]
Length = 353
Score = 89.3 bits (218), Expect = 3e-16
Identities = 56/114 (49%), Positives = 70/114 (61%), Gaps = 18/114 (15%)
Query: 553 NLPTVLH-------NTTAALALARELFGEN-WRHNFLELNASDERGINVIREKVKEFAR- 603
NLP +L T+ LAL +EL+G + + LELNASDERGI+++REKVK FAR
Sbjct: 57 NLPHMLFYGPPGTGKTSTILALTKELYGPDLMKSRILELNASDERGISIVREKVKNFARL 116
Query: 604 --TKPIGG-------ASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
+KP +KII LDEAD++T DAQ ALRRTME +S RF L C
Sbjct: 117 TVSKPSKHDLENYPCPPYKIIILDEADSMTADAQSALRRTMETYSGVTRFCLIC 170
Score = 82.3 bits (200), Expect = 3e-14
Identities = 59/183 (32%), Positives = 94/183 (51%), Gaps = 8/183 (4%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY ++II+P+ SRC+ FRF+ L+ + RLR+I+E E ++ + L+ IL I+ GD+R
Sbjct: 170 CNYVTRIIDPLASRCSKFRFKALDASNAIDRLRFISEQENVKCDDGVLERILDISAGDLR 229
Query: 1316 RAINILQAAA------ALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLRE 1369
R I +LQ+A+ + IT V +A P DI ++ +K +K
Sbjct: 230 RGITLLQSASKGAQYLGDGKNITSTQVEELAG-VVPHDILIEIVEKVKSGDFDEIKKYVN 288
Query: 1370 ILLKQGLSGEDVLVQMHR-EVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLA 1428
+K G S V+ Q+H + N D K ++ + + RL G NE IQL LL
Sbjct: 289 TFMKSGWSAASVVNQLHEYYITNDNFDTNFKNQISWLLFTTDSRLNNGTNEHIQLLNLLV 348
Query: 1429 QFT 1431
+ +
Sbjct: 349 KIS 351
>emb|CAA06481.1| (AJ005334) replication factor C/activator 1 subunit [Cicer arietinum]
Length = 166
Score = 88.5 bits (216), Expect = 5e-16
Identities = 50/160 (31%), Positives = 90/160 (56%), Gaps = 1/160 (0%)
Query: 1274 RFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAALDRKITD 1333
RF L+D++I RL + + E + EGL+AI++ A+GDMR+A+N LQA + + +
Sbjct: 1 RFSRLSDQEILGRLMVVVQAEKVPYVPEGLEAIIFTADGDMRQALNNLQATYSGFQFVNQ 60
Query: 1334 ENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGEDVLVQMHREVFNLP 1393
NVF V + P ++ M+ ++GNF +A L++ L G S D++ + R + N
Sbjct: 61 ANVFKVCDQPHPLHVKNMVRNVIEGNFDEACSGLKQ-LYDLGYSPTDIITTLFRIIKNYD 119
Query: 1394 IDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLI 1433
+ E +K+ + G + R+ +G +Q+ LLA+ +L+
Sbjct: 120 MAEYLKLEFMKETGFAHMRICDGVGSYLQMCGLLAKLSLV 159
>pir||H71604 replication factor C, 40 kDa subunit (replication activator)
PFB0840w - malaria parasite (Plasmodium falciparum)
>gi|3845290|gb|AAC71957.1| (AE001420) replication factor
C, 40 kDa subunit (replication activator) [Plasmodium
falciparum]
Length = 330
Score = 88.5 bits (216), Expect = 5e-16
Identities = 52/100 (52%), Positives = 67/100 (67%), Gaps = 13/100 (13%)
Query: 561 TTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFAR-----------TKPIG 608
T+A ALA ELFG EN LELNASD+RGINV+REK+K + R TK +
Sbjct: 51 TSAINALAHELFGKENISERVLELNASDDRGINVVREKIKAYTRISISKNKIHSETKEVL 110
Query: 609 GASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
S+K++ LDEAD +T+DAQ ALRR +E++S+ RFIL C
Sbjct: 111 -PSWKLVVLDEADMMTEDAQSALRRIIEIYSNVTRFILIC 149
Score = 85.4 bits (208), Expect = 4e-15
Identities = 52/169 (30%), Positives = 94/169 (54%), Gaps = 2/169 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY KI +PI SRC+ +RF+ + ++L YI +NE +++ ++ L+ I+ EGD+R
Sbjct: 149 CNYIHKISDPIFSRCSCYRFQSIPINIKKEKLLYICQNENIDIVDDALEKIIETTEGDLR 208
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
RA++ILQ + ++ KIT +V L S ++I ++ A K LK EK + +++ G
Sbjct: 209 RAVSILQLCSCINTKITLNSV-LDVSGLPSDNIVYKIIDACKMKDLKLVEKTVQDIIEDG 267
Query: 1376 LSGEDVLVQMHRE-VFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQL 1423
+ + V N ++ +K + ++ +++RL GA + IQL
Sbjct: 268 FDVAYIFKSFNNYFVTNTEYEDSLKYQILLELSRHDYRLHCGATQYIQL 316
>gb|AAG37987.1|AF071409_1 (AF071409) replication factor C subunit 2; RFC2 [Plasmodium
falciparum]
Length = 330
Score = 88.5 bits (216), Expect = 5e-16
Identities = 52/100 (52%), Positives = 67/100 (67%), Gaps = 13/100 (13%)
Query: 561 TTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFAR-----------TKPIG 608
T+A ALA ELFG EN LELNASD+RGINV+REK+K + R TK +
Sbjct: 51 TSAINALAHELFGKENISERVLELNASDDRGINVVREKIKAYTRISISKNKIHSETKEVL 110
Query: 609 GASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
S+K++ LDEAD +T+DAQ ALRR +E++S+ RFIL C
Sbjct: 111 -PSWKLVVLDEADMMTEDAQSALRRIIEIYSNVTRFILIC 149
Score = 84.3 bits (205), Expect = 9e-15
Identities = 52/169 (30%), Positives = 94/169 (54%), Gaps = 2/169 (1%)
Query: 1256 CNYSSKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMR 1315
CNY KI +PI SRC+ +RF+ + ++L YI +NE +++ ++ L+ I+ EGD+R
Sbjct: 149 CNYIHKISDPIFSRCSCYRFQSIPINIKKEKLLYICQNENIDIVDDALEKIIETTEGDLR 208
Query: 1316 RAINILQAAAALDRKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQG 1375
RA++ILQ + ++ KIT +V L S ++I ++ A K LK EK + +++ G
Sbjct: 209 RAVSILQLCSCINTKITLNSV-LDVSGLPSDNIVYKIIDACKMKDLKLVEKTVQDIIEDG 267
Query: 1376 LSGEDVLVQMHRE-VFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQL 1423
+ + V N ++ +K + ++ +++RL GA + IQL
Sbjct: 268 FDVAYIFKSFNNYFVTNTEYEDSLKYQILLELFRHDYRLHCGATQYIQL 316
>emb|CAB92098.1| (AL356333) Replication factor C 36 KD subunit; activator 1 36 kd
subunit [Schizosaccharomyces pombe]
Length = 142
Score = 86.2 bits (210), Expect = 2e-15
Identities = 40/73 (54%), Positives = 57/73 (77%)
Query: 561 TTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEA 620
T+ LA AR+++G N+R+ +ELNASD+RGI+ +RE++K FA T+ I ++FK+I LDEA
Sbjct: 70 TSTILACARKIYGPNYRNQLMELNASDDRGIDAVREQIKNFASTRQIFASTFKMIILDEA 129
Query: 621 DALTQDAQQALRR 633
DA+T AQ ALRR
Sbjct: 130 DAMTLAAQNALRR 142
>sp|P53016|AC12_CAEEL PUTATIVE ACTIVATOR 1 37 KD SUBUNIT (REPLICATION FACTOR C 37 KD
SUBUNIT) (A1 37 KD SUBUNIT) (RF-C 37 KD SUBUNIT) (RFC37)
>gi|7444554|pir||T16219 hypothetical protein F31E3.3 -
Caenorhabditis elegans >gi|1072162|gb|AAA81689.1|
(U40935) similar to replication factor C 37 kda subunit
(human) and F44B9.8 [Caenorhabditis elegans]
Length = 334
Score = 83.9 bits (204), Expect = 1e-14
Identities = 47/95 (49%), Positives = 66/95 (69%), Gaps = 8/95 (8%)
Query: 561 TTAALALARELFGENWRHN-FLELNASDERGINVIREKVKEFARTKPIGGA------SFK 613
T+AALA R+LF +N H+ L+LNASDERGI V+R+K++ F+++ +G + K
Sbjct: 62 TSAALAFCRQLFPKNIFHDRVLDLNASDERGIAVVRQKIQSFSKSS-LGHSHREDVLKLK 120
Query: 614 IIFLDEADALTQDAQQALRRTMEMFSSNVRFILSC 648
II LDE DA+T++AQ A+RR +E FS RFIL C
Sbjct: 121 IIILDEVDAMTREAQAAMRRVIEDFSKTTRFILIC 155
>gb|AAG20362.1| (AE005110) replication factor C small subunit; RfcC [Halobacterium
sp. NRC-1]
Length = 334
Score = 71.0 bits (171), Expect = 9e-11
Identities = 53/174 (30%), Positives = 87/174 (49%), Gaps = 8/174 (4%)
Query: 1260 SKIIEPIQSRCAIFRFRPLNDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAIN 1319
SK+I PI SRC R D ++ LR I EG++ +GL+ + AEGD+R A+
Sbjct: 162 SKLIPPIHSRCFPVSVRAPTDNEVVDVLREIVAAEGVDYEPDGLEFVAGYAEGDLREAVL 221
Query: 1320 ILQAAAALDRKITDENVFLVASRARPEDIREMML-LALKGNFLKAREKLREILLKQGLSG 1378
Q A + ++T + + E ML A G F AR L ++L+ +G+SG
Sbjct: 222 GAQTTAEQEGEVTMNAAYEALQDVGSDAAVESMLDDAEAGAFTDARSTLDDLLVDEGMSG 281
Query: 1379 EDV---LVQMHREVFNLPIDEPMKVYLADKIGEYNFRLVEGANEMIQLEALLAQ 1429
+V L+++ R ++ D+ ++Y G+ F L G ++ +QL LLA+
Sbjct: 282 GEVLDDLLEVARSRYS--GDDVAELYAL--AGDVEFDLTRGTSDRVQLGRLLAE 331
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.138 0.388
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 523094182
Number of Sequences: 2977
Number of extensions: 23434751
Number of successful extensions: 78354
Number of sequences better than 1.0e-10: 55
Number of HSP's better than 0.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 78065
Number of HSP's gapped (non-prelim): 172
length of query: 1437
length of database: 189,106,746
effective HSP length: 62
effective length of query: 1375
effective length of database: 152,000,552
effective search space: 209000759000
effective search space used: 209000759000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 171 (71.0 bits)