BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0081 (PAB0081) DE:Hypothetical protein
(300 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75200 hypothetical protein PAB0081 - Pyrococcus abyssi (st... 585 e-166
pir||D71234 hypothetical protein PH0134 - Pyrococcus horikoshii ... 563 e-160
gi|11499613 A. fulgidus predicted coding region AF2031 [Archaeog... 146 3e-34
pir||C69084 phosphoserine phosphatase - Methanobacterium thermoa... 132 6e-30
gb|AAG18950.1| (AE004996) Vng0394c [Halobacterium sp. NRC-1] 117 2e-25
emb|CAC12606.1| (AL445067) conserved hypothetical protein [Therm... 101 1e-20
pir||H72670 hypothetical protein APE0790 - Aeropyrum pernix (str... 94 1e-18
sp|P37709|TRHY_RABIT TRICHOHYALIN >gi|280938|pir||S28589 trichoh... 82 6e-15
pir||A64465 hypothetical protein MJ1322 - Methanococcus jannasch... 80 3e-14
gb|AAB62657.1| (U93872) ORF 73, contains large complex repeat CR... 79 7e-14
pir||A70387 conserved hypothetical protein aq_1006 - Aquifex aeo... 78 2e-13
gb|AAF48098.1| (AE003487) CG1905 gene product [Drosophila melano... 77 3e-13
dbj|BAA36494.1| (AB022023) nonmuscle myosin heavy chain B [Bos t... 76 3e-13
pir||B70356 chromosome assembly protein homolog - Aquifex aeolic... 76 4e-13
pir||F71190 probable chromosome assembly protein - Pyrococcus ho... 76 4e-13
gb|AAK42417.1| Purine NTPase [Sulfolobus solfataricus] 76 6e-13
gi|11499153 chromosome segregation protein (smc1) [Archaeoglobus... 76 6e-13
sp|P35580|MYSO_HUMAN MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B (CELLU... 75 1e-12
emb|CAA71688.1| (Y10687) purine NTPase [Sulfolobus acidocaldarius] 75 1e-12
pir||C71622 hypothetical protein PFB0145c - malaria parasite (Pl... 74 2e-12
pir||B75150 chromosome segregation protein (smc1) PAB2109 - Pyro... 74 2e-12
gb|AAF61445.1|AF139055_1 (AF139055) nonmuscle myosin heavy chain... 74 2e-12
gb|AAC72233.1| (AF092090) cp151 [Rattus norvegicus] 73 3e-12
gb|AAK41222.1| Hypothetical protein [Sulfolobus solfataricus] 73 4e-12
gb|AAF07789.1|AC010704_14 (AC010704) hypothetical protein; 57314... 73 4e-12
dbj|BAB06206.1| (AP001515) chromosome segregation SMC protein [B... 73 4e-12
gi|4502781 centromere protein E; Centromere autoantigen E (312kD... 72 7e-12
prf||1819485A CENP-E protein [Homo sapiens] 72 7e-12
pir||T47237 myosin II heavy chain [imported] - Naegleria fowleri... 72 7e-12
gb|AAD46501.1|AF148805_6 (AF148805) latent nuclear antigen [Kapo... 72 9e-12
gi|11421723 centrosomal protein 2 [Homo sapiens] >gi|7671665|emb... 72 9e-12
gi|11498637 purine NTPase, putative [Archaeoglobus fulgidus] >gi... 72 9e-12
gi|6005729 centrosomal protein 2; centrosome associated protein ... 72 9e-12
pir||A45592 liver stage antigen LSA-1 - malaria parasite (Plasmo... 71 1e-11
pir||A64505 P115 homolog - Methanococcus jannaschii 71 1e-11
gb|AAB99663.1| (U67604) chromosome segretation protein (smc1) [M... 71 1e-11
pir||A72287 hypothetical protein TM1182 - Thermotoga maritima (s... 71 1e-11
dbj|BAA92557.1| (AB037740) KIAA1319 protein [Homo sapiens] 71 1e-11
gb|AAF74498.1|AF263462_1 (AF263462) cingulin [Homo sapiens] 71 1e-11
gb|AAG27458.1|AF305694_1 (AF305694) latent nuclear antigen [Kapo... 71 1e-11
sp|P54697|MYSJ_DICDI MYOSIN IJ HEAVY CHAIN >gi|7489890|pir||T182... 71 1e-11
prf||2012303A SP-H antigen [Homo sapiens] 71 2e-11
pir||T08621 centrosome associated protein CEP250 - human >gi|283... 71 2e-11
gb|AAD19746.1| (AF132478) Ese1 protein [Mus musculus] 71 2e-11
gi|6754392 intersectin (SH3 domain protein 1A); intersection (SH... 71 2e-11
pir||S23647 NuMA protein - human >gi|35119|emb|CAA77669.1| (Z115... 71 2e-11
gi|11432935 nuclear mitotic apparatus protein 1 [Homo sapiens] 71 2e-11
pir||T24635 hypothetical protein T07C4.10a - Caenorhabditis eleg... 70 3e-11
pir||F75103 probable purine NTPase PAB0812 - Pyrococcus abyssi (... 70 3e-11
sp|P25386|USO1_YEAST INTRACELLULAR PROTEIN TRANSPORT PROTEIN USO... 69 4e-11
sp|P13538|MYSS_CHICK MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT ... 69 4e-11
pir||S05515 myosin heavy chain, skeletal muscle - chicken (fragm... 69 4e-11
gb|AAA72295.1| (L04159) [Plasmodium falciparum 3' end.], gene pr... 69 4e-11
gi|6320145 Integrin analogue gene; Uso1p [Saccharomyces cerevisi... 69 4e-11
pir||T07111 MAR binding filament-like protein 1 - tomato >gi|177... 69 4e-11
emb|CAA98620.1| (Z74105) ORF YDL058w [Saccharomyces cerevisiae] 69 4e-11
gi|9910570 sperm tail associated protein [Mus musculus] >gi|5525... 69 4e-11
gb|AAA48986.1| (M93676) nonmuscle myosin heavy chain [Gallus gal... 69 6e-11
gb|AAA48987.1| (M93676) nonmuscle myosin heavy chain [Gallus gal... 69 6e-11
pir||B43402 myosin heavy chain-B, neuronal - chicken >gi|212452|... 69 6e-11
pir||T41023 probable nuclear pore complex-associated protein - f... 69 6e-11
gb|AAA48985.1| (M93676) nonmuscle myosin heavy chain [Gallus gal... 69 6e-11
pir||A59282 nonmuscle myosin II heavy chain A - African clawed f... 69 6e-11
pir||S21801 myosin heavy chain, neuronal [similarity] - rat 69 8e-11
sp|P15924|DESP_HUMAN DESMOPLAKIN I AND II (DPI AND DPII) >gi|181... 69 8e-11
gi|4758200 desmoplakin (DPI, DPII); Desmoplakin [Homo sapiens] >... 69 8e-11
pir||A38194 desmoplakin I - human 69 8e-11
emb|CAA19927.1| (AL031058) dJ512B11.1 (Desmoplakin I (DPI)) [Hom... 69 8e-11
gi|11418894 desmoplakin (DPI, DPII) [Homo sapiens] 69 8e-11
gi|5453820 nuclear mitotic apparatus protein 1 [Homo sapiens] >g... 68 1e-10
sp|P08799|MYS2_DICDI MYOSIN II HEAVY CHAIN, NON MUSCLE >gi|84128... 68 1e-10
sp|Q99105|MYSU_RABIT MYOSIN HEAVY CHAIN, EMBRYONIC SMOOTH MUSCLE... 68 1e-10
gi|7662062 KIAA0336 gene product [Homo sapiens] >gi|2224613|dbj|... 68 1e-10
gb|AAD12213.1| (AC006135) putative vicilin storage protein (glob... 68 1e-10
dbj|BAA93660.1| (AB026497) myosin containing PDZ domain [Mus mus... 68 1e-10
>pir||H75200 hypothetical protein PAB0081 - Pyrococcus abyssi (strain Orsay)
>gi|5457564|emb|CAB49055.1| (AJ248283) hypothetical
protein [Pyrococcus abyssi]
Length = 300
Score = 585 bits (1492), Expect = e-166
Identities = 300/300 (100%), Positives = 300/300 (100%)
Query: 1 MQVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAR 60
MQVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAR
Sbjct: 1 MQVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAR 60
Query: 61 EFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEER 120
EFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEER
Sbjct: 61 EFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEER 120
Query: 121 IEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKAR 180
IEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKAR
Sbjct: 121 IEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKAR 180
Query: 181 RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIE 240
RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIE
Sbjct: 181 RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIE 240
Query: 241 RKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQRYNLV 300
RKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQRYNLV
Sbjct: 241 RKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQRYNLV 300
>pir||D71234 hypothetical protein PH0134 - Pyrococcus horikoshii
>gi|3256520|dbj|BAA29203.1| (AP000001) 300aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 300
Score = 563 bits (1435), Expect = e-160
Identities = 285/300 (95%), Positives = 294/300 (98%)
Query: 1 MQVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAR 60
MQVKVDPEEIKRIKRELEEL EKR IE+KLEELQKELN W+QKRDEKNLEVKRLREKAR
Sbjct: 1 MQVKVDPEEIKRIKRELEELQEEKRKIEIKLEELQKELNTWIQKRDEKNLEVKRLREKAR 60
Query: 61 EFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEER 120
EFKAKRDEINQRIKELKKNRDEINAKLDLLYQE LEYRTKRDEF+QLRRLKMPKEKIEER
Sbjct: 61 EFKAKRDEINQRIKELKKNRDEINAKLDLLYQEVLEYRTKRDEFKQLRRLKMPKEKIEER 120
Query: 121 IEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKAR 180
IEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKAR
Sbjct: 121 IEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKAR 180
Query: 181 RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIE 240
RAISMEIQQLANQSQQFHEQMIKTYQ+ADEVKKEADEYHQKV+ELREKIREVRRELRE+E
Sbjct: 181 RAISMEIQQLANQSQQFHEQMIKTYQRADEVKKEADEYHQKVLELREKIREVRRELREVE 240
Query: 241 RKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQRYNLV 300
+KILEYDQKHKELIAYKLVARM+AKRD NFEKAVQALEKFKRGEKLT+DEILLLQRYNLV
Sbjct: 241 KKILEYDQKHKELIAYKLVARMKAKRDANFEKAVQALEKFKRGEKLTWDEILLLQRYNLV 300
>gi|11499613 A. fulgidus predicted coding region AF2031 [Archaeoglobus fulgidus]
>gi|7483752|pir||F69503 hypothetical protein AF2031 -
Archaeoglobus fulgidus >gi|2648520|gb|AAB89238.1|
(AE000963) A. fulgidus predicted coding region AF2031
[Archaeoglobus fulgidus]
Length = 286
Score = 146 bits (364), Expect = 3e-34
Identities = 84/292 (28%), Positives = 170/292 (57%), Gaps = 9/292 (3%)
Query: 10 IKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEI 69
+++++ E+L E ++ K +EL + +RDE N +V+ + +E KAKRDE+
Sbjct: 3 LEKLEERKEQLEKELQDFIKKRDELNAAAREYANRRDELNKKVREMLAATKEVKAKRDEL 62
Query: 70 NQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWELQ 129
N ++KE++ R+EI ++D LY+E + R R + + P +IE+ I +LE++ Q
Sbjct: 63 NAKVKEIRAKRNEIFKEVDALYKEVDKLR------RSIDKGGRPLGEIEKEIRRLEFKQQ 116
Query: 130 TTPNISPEREKQIVDQIQVLATELEIIQ-QIERYNNKLQEVRKKIDQLKKARRAISMEIQ 188
T ++ E+E+ +V++I L ELE + Q+ER+ + + + +I +LK R + E++
Sbjct: 117 TAV-LTIEKERALVERIAKLRKELEERKAQLERHE-EFKRLISRIRELKDQARELLNELK 174
Query: 189 QLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILEYDQ 248
A ++ ++HEQ+ + + + DE++K ADE H+K +E +++ E + + I + ++
Sbjct: 175 AYAEEADKYHEQLTQMFSEIDEMRKLADEMHEKFIESKKEADRCHNEAIKRRKDIKDLEK 234
Query: 249 KHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQRYNLV 300
K L + ++ + + +++ +A + E FKRGEK+ +++L+LQR L+
Sbjct: 235 VIKALKSKQVKTKEQREKEELIRRAKEIYEMFKRGEKIETEDLLILQRAGLI 286
>pir||C69084 phosphoserine phosphatase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622752|gb|AAB86099.1| (AE000921)
phosphoserine phosphatase [Methanobacterium
thermoautotrophicum]
Length = 495
Score = 132 bits (328), Expect = 6e-30
Identities = 88/287 (30%), Positives = 156/287 (53%), Gaps = 19/287 (6%)
Query: 30 KLEELQKELNIWVQKRDEKNLEVKR-LREKAREFKAKRDEINQRIKELKKNRDEINAKLD 88
K+ E +LN + ++ +E+K +K ++RDE+N++ +E+K+ RD +N++L
Sbjct: 212 KVAEADDKLN---KMSYDEVMELKNEYEDKLSAIASERDELNKKAREMKELRDSLNSELR 268
Query: 89 LLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKLEWELQTTPNISPEREKQIVDQI- 146
A+E R KR+E ++ K +++I + I KLEW I E E + +D+I
Sbjct: 269 ETLNRAVELRDKRNEINSKVEENKKLRDQINKEIRKLEWSSGGRDRIKIENEIKRIDKII 328
Query: 147 --QVLAT--ELEIIQQIERYNNKLQ------EVRKKIDQLKKARRAISMEIQQLANQSQQ 196
+VL E E+++ KL E R+K +L+K ++ L+ ++Q
Sbjct: 329 ETRVLDINKENELVKTANELRKKLMKIQEDDETREKALELRKKSEEYHEKVVALSEEAQG 388
Query: 197 FHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILEYDQKHKELIAY 256
+HE+M++ ++K DE++K+ADE H+K +E R E E + +I + +++ L +
Sbjct: 389 YHEKMLEYFRKTDEIRKKADEAHEKFLEFRRMASEKHEEFKSTLGEIRQINERINALRSE 448
Query: 257 KLVARMRAKRDVNF---EKAVQALEKFKRGEKLTYDEILLLQRYNLV 300
AR R R+ + E+A + EKFK G+KLT DEILLLQ++ +V
Sbjct: 449 NRSARRRESREKDIEEKERAREIYEKFKEGKKLTKDEILLLQKHRIV 495
>gb|AAG18950.1| (AE004996) Vng0394c [Halobacterium sp. NRC-1]
Length = 300
Score = 117 bits (290), Expect = 2e-25
Identities = 72/264 (27%), Positives = 151/264 (56%), Gaps = 10/264 (3%)
Query: 33 ELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQ 92
EL + + +RD+ N + + ++A+E + KRDE+N+R++E K+ R+++NA + L+
Sbjct: 43 ELNQLASSRASERDDLNAKTREKVDEAQEHREKRDELNERVQEHKEIRNDLNADANELFD 102
Query: 93 EALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATE 152
E +E R + E + + L E+++E IE+LE++ QT +S E E++++++I+ E
Sbjct: 103 E-VEQRKEDLELDEGKDL----EQLKEEIEELEFKQQTEV-LSTEDERELIEKIEGKREE 156
Query: 153 LEIIQQIERYNNKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVK 212
+ ++ + L+ + ++ + ++ ++ +LA+++Q+ H QMI+ Y++AD+++
Sbjct: 157 YQDREEKLDQSGDLEGLVEEAESVRAEASKHHEKVTELADKAQEHHNQMIEAYREADDIR 216
Query: 213 KEADEYHQKVVELREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEK 272
EADE H+ VE +E E+++++ E D++ +E K R E+
Sbjct: 217 DEADEMHEDFVEAQEAADAHHEAFVEVQKRLRELDKQEEEEEKDKRAQEQEEAR----EE 272
Query: 273 AVQALEKFKRGEKLTYDEILLLQR 296
A + E+FK GE L +++ LQ+
Sbjct: 273 AEEIYERFKEGETLDTEDLRKLQK 296
>emb|CAC12606.1| (AL445067) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 295
Score = 101 bits (249), Expect = 1e-20
Identities = 74/296 (25%), Positives = 150/296 (50%), Gaps = 34/296 (11%)
Query: 25 RNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIKELKKNRDEIN 84
+ E K + L+K + ++KRDE +++R + +RD++N + E+ RD++
Sbjct: 6 QEFEEKRDILRKAIEEHIKKRDEA-------AQQSRNYAEQRDQLNAKAHEM---RDQVK 55
Query: 85 AKL---DLLYQEALEYRTKRDE-FRQLRRLKMPKEKIEER----------IEKLEWEL-- 128
K+ + L +E + RT+++E F++L L+ +KI E I+ E EL
Sbjct: 56 QKISQKNALIEEVQKIRTEKEEHFQKLSELRKEYKKITEEANYASVNQRDIKAKERELQK 115
Query: 129 ----QTTPNISPEREKQIVDQIQVLATELEIIQQIER----YNNKLQEVRKKIDQLKKAR 180
Q T + E ++V +I+ L+ E++ +++ N K++ + +ID+ K
Sbjct: 116 LIKKQETMQLPKAEEDKVVQEIKRLSNEIKKMKEDREKQLSENEKVKALLAEIDKEKTLA 175
Query: 181 RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIE 240
R + ++++NQ + + K+ Q+ DEV+K+ADE H+ ++ ++ + + +
Sbjct: 176 RDLKKRAEEISNQISEISNDINKSLQELDEVRKKADEMHEMAIKYGKESEQEHEAFIQAK 235
Query: 241 RKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQR 296
+ + ++ L K + + K D +KA EKFK GE+LT D++L+LQ+
Sbjct: 236 NDLKDLEKVIAGLRTKKRATKKKEKDDELQQKAEVLFEKFKNGEELTTDDLLILQK 291
>pir||H72670 hypothetical protein APE0790 - Aeropyrum pernix (strain K1)
>gi|5104453|dbj|BAA79768.1| (AP000060) 297aa long
hypothetical protein [Aeropyrum pernix]
Length = 297
Score = 94.4 bits (231), Expect = 1e-18
Identities = 75/309 (24%), Positives = 158/309 (50%), Gaps = 49/309 (15%)
Query: 15 RELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIK 74
R + E E+ + +EEL++E+ ++R + EVK LRE+ R+ ++ E ++++
Sbjct: 4 RSIAEFKKEEEELLKTIEELKEEIVRLKEERRKLINEVKALREERRKASREKREYVEKLR 63
Query: 75 ELKKNRDEINAKLDLLYQEALEYRT----KRDEFRQLRRL---------KMPKEKIEERI 121
L++ R +I +L L +E + R KRD+ R LR L K+ ++++ R+
Sbjct: 64 SLREERKKILDELAQLKEERKKTRDELVIKRDQLRVLRGLLEKEGGRLAKISLKRLQRRL 123
Query: 122 EKLEWELQTTPNISPEREKQIVDQI---------------QVLATELEIIQQIERYNNKL 166
++LE +Q T + PE EK++V++I Q L+T +E+ +++ KL
Sbjct: 124 QELEM-MQMTRVLRPEEEKRLVEEISRLEELIERVRKAKEQALST-MELQAEVKALVIKL 181
Query: 167 QEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELR 226
+++ ++ID+L++ ++ E+ L+++ ++++E++ K ++ ++ DE +++ L
Sbjct: 182 KDLNQRIDELRQQAGSVKEELATLSSKIEEYNERIKKLSEEIEKRSTRIDELSKEIDNLY 241
Query: 227 EKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQAL-EKFKRGEK 285
K REV L++I +A R EK + + +K ++GE
Sbjct: 242 AKYREVMTRLKDIR------------------IAMARGMELSEVEKRREEIKKKMEKGEP 283
Query: 286 LTYDEILLL 294
LT +E+ L+
Sbjct: 284 LTLEELKLI 292
Score = 78.8 bits (191), Expect = 7e-14
Identities = 64/265 (24%), Positives = 132/265 (49%), Gaps = 32/265 (12%)
Query: 10 IKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEI 69
I+ +K E+ L E+R + +++ L++E + EK V++LR E K DE+
Sbjct: 20 IEELKEEIVRLKEERRKLINEVKALREERR---KASREKREYVEKLRSLREERKKILDEL 76
Query: 70 NQRIKELKKNRDEINAKLD-------LLYQEA----------LEYRTKRDEFRQLRRLKM 112
Q +E KK RDE+ K D LL +E L+ R + E Q+ R+
Sbjct: 77 AQLKEERKKTRDELVIKRDQLRVLRGLLEKEGGRLAKISLKRLQRRLQELEMMQMTRVLR 136
Query: 113 PKE--KIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVR 170
P+E ++ E I +LE ++ + ++Q + +++ A ++ +++ N ++ E+R
Sbjct: 137 PEEEKRLVEEISRLEELIERV----RKAKEQALSTMELQAEVKALVIKLKDLNQRIDELR 192
Query: 171 KKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIR 230
++ +K+ +S +I++ + ++ E++ K + DE+ KE D + K E+ +++
Sbjct: 193 QQAGSVKEELATLSSKIEEYNERIKKLSEEIEKRSTRIDELSKEIDNLYAKYREVMTRLK 252
Query: 231 EVR------RELREIERKILEYDQK 249
++R EL E+E++ E +K
Sbjct: 253 DIRIAMARGMELSEVEKRREEIKKK 277
>sp|P37709|TRHY_RABIT TRICHOHYALIN >gi|280938|pir||S28589 trichohyalin - rabbit
>gi|1747|emb|CAA79519.1| (Z19092) trichohyalin
[Oryctolagus cuniculus]
Length = 1407
Score = 82.3 bits (200), Expect = 6e-15
Identities = 78/298 (26%), Positives = 163/298 (54%), Gaps = 20/298 (6%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEE--LQKELNIWVQKRDEKNLEVKRLREKAREFKAK 65
EE + +++E +EL E+ +L+ EE L++E + Q+RD K E ++L +++ E + +
Sbjct: 700 EEEQLLRQEEQELRQERER-KLREEEQLLRREEQLLRQERDRKLREEEQLLQESEEERLR 758
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDE-FRQLR-RLKMPKEKIEERIEK 123
R E R ++L++ RD + + L QE E R +R E R+LR ++ +E+ EER+ +
Sbjct: 759 RQE---REQQLRRERDRKFREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRR 815
Query: 124 LEWE--LQTTPNISPEREKQIV---DQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKK 178
E E L+ + ERE++ + ++ + L E ++++Q E+ QE +K+ + ++
Sbjct: 816 QERERKLREEEQLLQEREEERLRRQERERKLREEEQLLRQEEQ--ELRQERARKLREEEQ 873
Query: 179 ARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELRE 238
R E++Q ++ + EQ+++ Q+ E+++E D ++ +L ++ E R +E
Sbjct: 874 LLRQEEQELRQERDRKLREEEQLLR--QEEQELRQERDRKLREEEQLLQESEEERLRRQE 931
Query: 239 IERKILEYDQ---KHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILL 293
ERK+ E +Q + ++ + + ++R + + E+ + L + +R KL +E LL
Sbjct: 932 RERKLREEEQLLRREEQELRRERARKLREEEQLLQEREEERLRRQERARKLREEEQLL 989
Score = 78.8 bits (191), Expect = 7e-14
Identities = 76/297 (25%), Positives = 158/297 (52%), Gaps = 33/297 (11%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
+E +R RELEEL E++ + KL E ++ L Q+R+E+ L R +E+ R+ + +
Sbjct: 583 QERERQYRELEELRQEEQLRDRKLREEEQLL----QEREEERL---RRQERERKLREEEQ 635
Query: 68 EINQRIKELKKNRD-EINAKLDLLYQEALEYRTKRDEFRQLR-RLKMPKEKIEERIEKLE 125
+ Q +EL++ R+ ++ + LL +E E R +R+ R+LR ++ +E+ EER+ +
Sbjct: 636 LLRQEEQELRQERERKLREEEQLLRREEQELRQERE--RKLREEEQLLQEREEERLRR-- 691
Query: 126 WELQTTPNISPEREKQIVDQIQVL-ATELEIIQQIERYNNKLQEVRKKIDQLKKARRAIS 184
ER +++ ++ Q+L E E+ Q+ ER + +++ ++ +QL + R
Sbjct: 692 ----------QERARKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLRQERDRK 741
Query: 185 M-EIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKI 243
+ E +QL +S+ E+ ++ ++ ++++E D ++ +L ++ E R +E ERK+
Sbjct: 742 LREEEQLLQESE---EERLRRQEREQQLRRERDRKFREEEQLLQEREEERLRRQERERKL 798
Query: 244 LEYDQ-----KHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQ 295
E +Q + + L + ++R + + E+ + L + +R KL +E LL Q
Sbjct: 799 REEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLLRQ 855
Score = 72.6 bits (175), Expect = 5e-12
Identities = 74/315 (23%), Positives = 165/315 (51%), Gaps = 34/315 (10%)
Query: 8 EEIKRIKRELEELHNEK----RNIELKLEELQKELNIWVQKRDEKNLEVKR------LRE 57
EE + ++RE +EL E+ R E L+E ++E + Q+RD K E +R L E
Sbjct: 984 EEEQLLRREEQELRQERDRKFREEEQLLQEREEE-RLRRQERDRKFREEERQLRRQELEE 1042
Query: 58 KAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKI 117
+ R+ + ++ + ++I++ K+ + + D ++E + R +++ +QLRR + K +
Sbjct: 1043 QFRQERDRKFRLEEQIRQEKEEKQLRRQERDRKFREEEQQRRRQEREQQLRRERDRKFRE 1102
Query: 118 EERI--EKLEWELQTTPNISPEREKQIVDQIQVLATELEII-QQIERYNNKLQEVRKKID 174
EE++ E+ E L+ ER +++ ++ Q+L E +++ Q+ +R + +++ ++ +
Sbjct: 1103 EEQLLQEREEERLR-----RQERARKLREEEQLLRREEQLLRQERDRKFREEEQLLQESE 1157
Query: 175 QLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELRE----KIR 230
+ + R+ ++++ Q+ E+ ++ ++A ++++E Q+ ELR+ K+R
Sbjct: 1158 EERLRRQERERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERARKLR 1217
Query: 231 EVRRELREIERKI-LEYDQK--HKELIAYKLVARMRAKRDVNF--------EKAVQALEK 279
E + LR+ E+++ E D+K +E + + +R +RD F E+ + L +
Sbjct: 1218 EEEQLLRQEEQELRQERDRKFREEEQLLRREEQELRRERDRKFREEEQLLQEREEERLRR 1277
Query: 280 FKRGEKLTYDEILLL 294
+R KL +E LL
Sbjct: 1278 QERARKLREEEEQLL 1292
Score = 71.8 bits (173), Expect = 9e-12
Identities = 68/290 (23%), Positives = 140/290 (47%), Gaps = 32/290 (11%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
+E +R RE E+L E+ L+ +E +++L Q ++ E+++ E+AR+ + +
Sbjct: 816 QERERKLREEEQLLQEREEERLRRQERERKLREEEQLLRQEEQELRQ--ERARKLREEEQ 873
Query: 68 EINQRIKELKKNRD-EINAKLDLLYQEALEYRTKRDEFRQLRRLK-MPKEKIEERIEKLE 125
+ Q +EL++ RD ++ + LL QE E R +RD R+LR + + +E EER+ +
Sbjct: 874 LLRQEEQELRQERDRKLREEEQLLRQEEQELRQERD--RKLREEEQLLQESEEERLRR-- 929
Query: 126 WELQTTPNISPEREKQIVDQIQVLATE-----LEIIQQIERYNNKLQEVRKKIDQLKKAR 180
ERE+++ ++ Q+L E E +++ LQE ++ + ++
Sbjct: 930 ----------QERERKLREEEQLLRREEQELRRERARKLREEEQLLQEREEERLRRQERA 979
Query: 181 RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIE 240
R + E Q L + Q+ ++ + +++ +++ +E +E + E K RE R+LR
Sbjct: 980 RKLREEEQLLRREEQELRQERDRKFREEEQLLQEREEERLRRQERDRKFREEERQLRR-- 1037
Query: 241 RKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDE 290
Q+ +E + + R + + EK + L + +R K +E
Sbjct: 1038 -------QELEEQFRQERDRKFRLEEQIRQEKEEKQLRRQERDRKFREEE 1080
Score = 71.0 bits (171), Expect = 1e-11
Identities = 71/297 (23%), Positives = 148/297 (48%), Gaps = 19/297 (6%)
Query: 6 DPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAK 65
+ EE++R KR E + +L+ EE +K Q+R+ + E++ LR++ + K
Sbjct: 549 EEEELQREKRRQEREREYREEEKLQREEDEKRRR---QERERQYRELEELRQEEQLRDRK 605
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
E Q ++E ++ R + L +E R + E RQ R K+ +E E+ + + E
Sbjct: 606 LREEEQLLQEREEERLRRQERERKLREEEQLLRQEEQELRQERERKLREE--EQLLRREE 663
Query: 126 WELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQE----VRKKIDQLKKAR- 180
EL+ ERE+++ ++ Q+L E + + KL+E +R++ +L++ R
Sbjct: 664 QELR------QERERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERE 717
Query: 181 RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVR-RELREI 239
R + E Q L + Q ++ + ++ +++ +E++E + E +++R R R+ RE
Sbjct: 718 RKLREEEQLLRREEQLLRQERDRKLREEEQLLQESEEERLRRQEREQQLRRERDRKFREE 777
Query: 240 ERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQR 296
E+ + E ++ + L + ++R + + E+ + L + +R KL +E LL +R
Sbjct: 778 EQLLQE--REEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLLQER 832
Score = 69.5 bits (167), Expect = 4e-11
Identities = 77/323 (23%), Positives = 166/323 (50%), Gaps = 33/323 (10%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRL------ 55
+++ + + ++R ++EL + K E +L + ++E + Q+R K E ++L
Sbjct: 651 KLREEEQLLRREEQELRQERERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQEEQ 710
Query: 56 ---REKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDE-FRQLRRLK 111
+E+ R+ + + + + + L++ RD + + L QE+ E R +R E +QLRR +
Sbjct: 711 ELRQERERKLREEEQLLRREEQLLRQERDRKLREEEQLLQESEEERLRRQEREQQLRRER 770
Query: 112 ---------MPKEKIEERIEKLEWE--LQTTPNISPEREKQIV---DQIQVLATELEIIQ 157
+ +E+ EER+ + E E L+ + ERE++ + ++ + L E +++Q
Sbjct: 771 DRKFREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLLQ 830
Query: 158 QIERYNNKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADE 217
+ E + QE +K+ + ++ R E++Q + + EQ+++ Q+ E+++E D
Sbjct: 831 EREEERLRRQERERKLREEEQLLRQEEQELRQERARKLREEEQLLR--QEEQELRQERD- 887
Query: 218 YHQKVVELREKIREVRRELR-EIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQA 276
+K+ E + +R+ +ELR E +RK+ E +Q +E +L + R ++ E+ ++
Sbjct: 888 --RKLREEEQLLRQEEQELRQERDRKLREEEQLLQESEEERLRRQERERKLREEEQLLRR 945
Query: 277 LE---KFKRGEKLTYDEILLLQR 296
E + +R KL +E LL +R
Sbjct: 946 EEQELRRERARKLREEEQLLQER 968
Score = 68.3 bits (164), Expect = 1e-10
Identities = 71/296 (23%), Positives = 149/296 (49%), Gaps = 37/296 (12%)
Query: 5 VDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKA 64
++ E+++R RE +EL E R E + E +++ +Q+ +E+ L +R RE+ RE +
Sbjct: 201 IEEEQLRR--REQQELKRELREEEQQRRERREQHERALQEEEEQLLRQRRWREEPREQQQ 258
Query: 65 KRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKL 124
R E+ + + ++ E + L ++ LE +R++ QLRR E+I ER ++L
Sbjct: 259 LRRELEEIREREQRLEQEERREQQLRREQRLEQEERREQ--QLRR---ELEEIREREQRL 313
Query: 125 EWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAIS 184
E E ER +Q ++Q E QQ++R +L+E+R++ +L++ R
Sbjct: 314 EQE---------ERREQRLEQ------EERREQQLKR---ELEEIREREQRLEQEERREQ 355
Query: 185 MEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIRE-------VRRELR 237
+ +++ Q+++ E + + +Q+ +++ EA KV + E RR+ +
Sbjct: 356 LLAEEVREQARERGESLTRRWQR--QLESEAGARQSKVYSRPRRQEEQSLRQDQERRQRQ 413
Query: 238 EIERKILEYDQKHKELIAYKLVARMRAK---RDVNFEKAVQALEKFKRGEKLTYDE 290
E ER++ E ++ ++ A + R R + R E+ ++A E+ ++ ++ +E
Sbjct: 414 ERERELEEQARRQQQWQAEEESERRRQRLSARPSLRERQLRAEERQEQEQRFREEE 469
>pir||A64465 hypothetical protein MJ1322 - Methanococcus jannaschii
>gi|1591962|gb|AAB99331.1| (U67572) purine NTPase
[Methanococcus jannaschii]
Length = 1005
Score = 80.0 bits (194), Expect = 3e-14
Identities = 81/338 (23%), Positives = 145/338 (41%), Gaps = 60/338 (17%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKR---------------DEKNLEVK 53
E ++ E L EK++IE + +L+ +N +++ +EK ++
Sbjct: 406 EYNKLTLEYITLLQEKKSIEKNINDLETRINKLLEETKNIDIESIENSLKEIEEKKKVLE 465
Query: 54 RLREKAREFKAKRDEINQRIKELKKNRDEI----------------NAKLDLLYQEALEY 97
L+++ E K EIN IK LKK DE+ N K++L+ Q +
Sbjct: 466 NLQKEKIELNKKLGEINSEIKRLKKILDELKEVEGKCPLCKTPIDENKKMELINQHKTQL 525
Query: 98 RTKRDEFRQLRRLKMPKEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQ 157
K + +L + +IE+ IEKL+ E+ N+ + + Q Q+ EL
Sbjct: 526 NNK---YTELEEINKKIREIEKDIEKLKKEIDKEENLKTLKTLYLEKQSQIEELEL---- 578
Query: 158 QIERYNNKLQEVRKKIDQL---KKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKE 214
+++ Y +L E+ KKI K I +I+ N+ + F+ Q + + V +E
Sbjct: 579 KLKNYKEQLDEINKKISNYVINGKPVDEILEDIKSQLNKFKNFYNQYLSAVSYLNSVDEE 638
Query: 215 ADEYHQKVVE----------LREKIREVRRELREIER---KILEYDQKHKELIAYKLVAR 261
K +E RE++ ++R + REI R K+ E K KELI
Sbjct: 639 GIRNRIKEIENIVSGWNKEKCREELNKLREDEREINRLKDKLNELKNKEKELI------E 692
Query: 262 MRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQRYNL 299
+ +R + F+K + L ++ E+L + L + YN+
Sbjct: 693 IENRRSLKFDKYKEYLGLTEKLEELKNIKDGLEEIYNI 730
>gb|AAB62657.1| (U93872) ORF 73, contains large complex repeat CR 73 [Kaposi's
sarcoma-associated herpesvirus]
Length = 1089
Score = 78.8 bits (191), Expect = 7e-14
Identities = 57/287 (19%), Positives = 151/287 (51%), Gaps = 6/287 (2%)
Query: 6 DPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAK 65
+P++ + ++E ++ ++++ + + E+ Q E Q++DE+ + ++ E+ ++ + +
Sbjct: 552 EPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQ 611
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
+DE Q+ ++ ++ E + + QE E + ++ ++L + E+ E+ +E+ E
Sbjct: 612 QDEQQQQDEQEQQEEQEQQEEQE--QQEEQEQEQQEEQEQELEEQEQELEEQEQELEEQE 669
Query: 126 WELQTTPNISPEREKQIVDQIQVLAT-ELEIIQQIERYNNKLQEVRKKIDQLKKARRAIS 184
EL+ E+E+++ +Q Q L E E+ +Q + + QE+ ++ +L++ + +
Sbjct: 670 QELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELE 729
Query: 185 MEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKIL 244
+ Q+L Q Q+ EQ + ++ E++++ E ++ EL E+ +E+ + +E E + +
Sbjct: 730 EQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEV 789
Query: 245 EYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEI 291
E ++ +E + V +++ E+ Q LE+ + E+ +E+
Sbjct: 790 EEQEQEQEEQELEEVEEQEQEQE---EQEEQELEEVEEQEEQELEEV 833
Score = 74.5 bits (180), Expect = 1e-12
Identities = 55/280 (19%), Positives = 145/280 (51%), Gaps = 17/280 (6%)
Query: 6 DPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAK 65
+P++ + ++E ++ +++ + + E+ Q E Q++DE+ + ++ E+ ++ + +
Sbjct: 547 EPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQ 606
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
+DE Q + ++ +DE + + QE E + ++++ +Q E+ E+ +E+ E
Sbjct: 607 QDEQQQ---DEQQQQDEQEQQEEQEQQEEQEQQEEQEQEQQ--------EEQEQELEEQE 655
Query: 126 WELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAISM 185
EL+ E+E+++ +Q E E+ +Q + + QE+ ++ +L++ + +
Sbjct: 656 QELEEQEQELEEQEQELEEQ------EQELEEQEQELEEQEQELEEQEQELEEQEQELEE 709
Query: 186 EIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILE 245
+ Q+L Q Q+ EQ + ++ E++++ E ++ EL E+ +E+ + +E+E + E
Sbjct: 710 QEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQE 769
Query: 246 YDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEK 285
+++ +EL + + + E+ Q LE+ + E+
Sbjct: 770 LEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQ 809
Score = 71.8 bits (173), Expect = 9e-12
Identities = 54/228 (23%), Positives = 117/228 (50%), Gaps = 7/228 (3%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKARE 61
Q + + E+ + ++ELEE E E +LEE ++EL Q+ +E+ E++ ++ E
Sbjct: 636 QEEQEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEE 695
Query: 62 FKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQ-LRRLKMPKEKIEER 120
+ + +E Q ++E ++ +E +L+ QE E + +E Q L + E+ E+
Sbjct: 696 QEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQE 755
Query: 121 IEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKAR 180
+E+ E EL+ E+E+++ +Q Q E Q+ E+ +L+EV ++ + ++
Sbjct: 756 LEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEE-- 813
Query: 181 RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREK 228
E Q+L +Q +++ + ++ ++ +E +E Q+ VE +E+
Sbjct: 814 ----QEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQ 857
>pir||A70387 conserved hypothetical protein aq_1006 - Aquifex aeolicus
>gi|2983515|gb|AAC07092.1| (AE000718) hypothetical
protein [Aquifex aeolicus]
Length = 978
Score = 77.6 bits (188), Expect = 2e-13
Identities = 75/288 (26%), Positives = 152/288 (52%), Gaps = 52/288 (18%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDE-KNLE--VKRLREKAREFK- 63
EE+K +K E+L E + E K + L++EL+ V K E +NLE V++LREK EF
Sbjct: 214 EELKELKETEEKLRQELKKAEEK-DSLERELSQVVTKLKELENLEKEVEKLREKL-EFSR 271
Query: 64 --------AKR-DEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPK 114
AKR +EI++++ ELK ++++ +L +L E L + + +L R++ K
Sbjct: 272 KVAPYVPIAKRIEEIDKKLTELKVRKNKLTKELAVLKDE-LSFAQE-----ELNRIEAEK 325
Query: 115 EKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKID 174
EK +E EREK++ +++ L EI++++ + ++ L+E ++ +
Sbjct: 326 EKFKEE---------------KEREKELEHRLKKLQEIKEILKELSQLSSSLKEKEREYE 370
Query: 175 QLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRR 234
Q K+ E + L+ + ++ + + +T +K +++K+ E ++++E++
Sbjct: 371 QAKQ-------EFEDLSERVEKGKKLVAETEEKLEKIKELFSEEEYTSLKMKERL----- 418
Query: 235 ELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKR 282
L E++RK+ E +K +L L + + K+ V+ EK + L++ +R
Sbjct: 419 -LVELQRKLKELKEKEGQL--ENLTQKYKEKKKVH-EKVLNELKELER 462
Score = 73.4 bits (177), Expect = 3e-12
Identities = 52/266 (19%), Positives = 129/266 (47%), Gaps = 14/266 (5%)
Query: 7 PEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDE-------KNLEVKRLREKA 59
PE +K ++LEEL EK +E KL + +K L ++++E E++ L+EK
Sbjct: 556 PENLKERIKKLEELRIEKEKLEHKLNKYRKALEDRQKQKEEAQAKLHKAQTELELLKEKI 615
Query: 60 REFKAKRDEINQ--RIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQ-LRRLKMPKEK 116
RE E + R++ L+ + + +++ + + E K + R+ L K K
Sbjct: 616 REKSRLVKEFKELYRVERLEDYEESLKEEINYINSKLQEIEEKEKKLRKHFEELSSRKSK 675
Query: 117 IEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQL 176
+E + L + + E+ K++ + +V + E+++ +K E+ +KI +
Sbjct: 676 LEGELSALNESINSLEEERKEKLKELANIYEVAKSPREVVELY--LGDKEAELERKIKEF 733
Query: 177 KKARRAISMEIQQLANQSQQFH--EQMIKTYQKADEVKKEADEYHQKVVELREKIREVRR 234
+++ +++ ++ ++ + +++ ++ + + VK + +E H+K+ E++ ++ +
Sbjct: 734 EESFQSLKLKKSEIEEKLKEYEGIRELSDIKGEYESVKTQLEEKHKKLGEVKRELEHLGE 793
Query: 235 ELREIERKILEYDQKHKELIAYKLVA 260
L+ E E + K+L Y++++
Sbjct: 794 RLKRKEELQKEISELEKKLEVYRVIS 819
Score = 70.2 bits (169), Expect = 3e-11
Identities = 69/299 (23%), Positives = 138/299 (46%), Gaps = 37/299 (12%)
Query: 3 VKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREF 62
+K+ ++I +K E+E+L NE + ++ E KE ++K +E +E ++L K ++
Sbjct: 527 LKLYAQKINSLKEEMEKLRNEVEELRKEIPENLKER---IKKLEELRIEKEKLEHKLNKY 583
Query: 63 KAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQL---RRLKMPKEKIEE 119
+ ++ ++ +E + + +L+LL ++ E EF++L RL+ +E ++E
Sbjct: 584 RKALEDRQKQKEEAQAKLHKAQTELELLKEKIREKSRLVKEFKELYRVERLEDYEESLKE 643
Query: 120 RIEKLEWELQTTPNISPEREKQIVDQIQVLAT-----ELEIIQQIERYNNKLQEVRKKID 174
I + +LQ E+EK++ + L++ E E+ E N+ +E ++K+
Sbjct: 644 EINYINSKLQEI----EEKEKKLRKHFEELSSRKSKLEGELSALNESINSLEEERKEKLK 699
Query: 175 QL-------KKARRAISMEI----QQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVV 223
+L K R + + + +L + ++F E K E++++ EY
Sbjct: 700 ELANIYEVAKSPREVVELYLGDKEAELERKIKEFEESFQSLKLKKSEIEEKLKEY----- 754
Query: 224 ELREKIREVRRELREIERKILEYDQKHKELIAYKLVAR---MRAKRDVNFEKAVQALEK 279
E IRE+ E E + ++KHK+L K R KR +K + LEK
Sbjct: 755 ---EGIRELSDIKGEYESVKTQLEEKHKKLGEVKRELEHLGERLKRKEELQKEISELEK 810
>gb|AAF48098.1| (AE003487) CG1905 gene product [Drosophila melanogaster]
Length = 2274
Score = 76.9 bits (186), Expect = 3e-13
Identities = 70/302 (23%), Positives = 154/302 (50%), Gaps = 26/302 (8%)
Query: 5 VDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDE-------KNLEVKRLRE 57
+D E+ K ++EL+ E+ E KL+E +KE + +++R+E + L+ ++++E
Sbjct: 1350 IDKEKEKAKEKELKLKEKER---EAKLQEKEKEEKLKLKEREESLRMEREEKLKEEKIKE 1406
Query: 58 KAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKI 117
K RE K K ++I ++ +E K +++ K + E K E ++ +L+ K K
Sbjct: 1407 KEREEKLKEEKIKEKQREEKLKEEKLKEKEREERMKEKEREEKAKEKQREEKLREEKIKE 1466
Query: 118 EERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNN----KLQEVRKKI 173
+ER EKL+ +L+ E+E+++ + + E E ++I+ K +E +K+
Sbjct: 1467 KEREEKLKEKLREEKIKEKEKEEKLRKEREEKMREKEREEKIKEKERVEKIKEKEREEKL 1526
Query: 174 DQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVK-KEADEYHQKVVELREKIREV 232
+ K+ + E+ + + ++ E+ +K ++ +++K KE +E ++ E R++ +E
Sbjct: 1527 KKEKEEKLKEKEELLKKKEKEEKEREEKLKEKERQEKLKEKEREEKLKRETEERQREKER 1586
Query: 233 RRELREIER--------KILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGE 284
+L+E ER K ++ +K ++L + +++ K++ + V+ EK E
Sbjct: 1587 EEKLKEKERAEKLKDLEKEVKLKEKEEQLKEKEKELKLKEKKE---KDKVKEKEKSLESE 1643
Query: 285 KL 286
KL
Sbjct: 1644 KL 1645
Score = 73.7 bits (178), Expect = 2e-12
Identities = 72/270 (26%), Positives = 145/270 (53%), Gaps = 35/270 (12%)
Query: 8 EEIKRIKRE-LEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKR 66
E +++K E ++E E++ E K++E Q+E + +K EK E +R++EK RE KAK
Sbjct: 1394 EREEKLKEEKIKEKEREEKLKEEKIKEKQREEKLKEEKLKEKERE-ERMKEKEREEKAKE 1452
Query: 67 DEINQRIKELKKNRDEINAKL-DLLYQEALEYRTKRDEFRQLRRLKM----------PKE 115
+ ++++E K E KL + L +E ++ + K ++ R+ R KM KE
Sbjct: 1453 KQREEKLREEKIKEKEREEKLKEKLREEKIKEKEKEEKLRKEREEKMREKEREEKIKEKE 1512
Query: 116 KIE-----ERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVR 170
++E ER EKL+ E+E+++ ++ ++L + + ++ ER KL+E +
Sbjct: 1513 RVEKIKEKEREEKLK----------KEKEEKLKEKEELLKKKEK--EEKER-EEKLKE-K 1558
Query: 171 KKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIR 230
++ ++LK+ R ++ + Q ++ E+ +K ++A+++K E K+ E E+++
Sbjct: 1559 ERQEKLKEKEREEKLKRETEERQREKEREEKLKEKERAEKLKDLEKEV--KLKEKEEQLK 1616
Query: 231 EVRRELREIERKILE-YDQKHKELIAYKLV 259
E +EL+ E+K + +K K L + KL+
Sbjct: 1617 EKEKELKLKEKKEKDKVKEKEKSLESEKLL 1646
>dbj|BAA36494.1| (AB022023) nonmuscle myosin heavy chain B [Bos taurus]
Length = 1976
Score = 76.5 bits (185), Expect = 3e-13
Identities = 55/255 (21%), Positives = 122/255 (47%), Gaps = 20/255 (7%)
Query: 12 RIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQ 71
R E + E R E K L + L ++ R+E + K+LR + + +D++ +
Sbjct: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAREEAERQNKQLRADMEDLMSSKDDVGK 1525
Query: 72 RIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKL----EW 126
+ EL+K++ + Q+ E RT+ +E +L+ + K ++E ++ + E
Sbjct: 1526 NVHELEKSKRALE-------QQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1578
Query: 127 ELQTTPNISPEREKQIVDQIQVLATELE--------IIQQIERYNNKLQEVRKKIDQLKK 178
+LQT + E+++ ++ Q++ L ELE + ++ L+++ +I+ K
Sbjct: 1579 DLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANK 1638
Query: 179 ARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELRE 238
AR + ++++L Q + + ++ + DE+ ++ E +K+ L +I +++ EL
Sbjct: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELAS 1698
Query: 239 IERKILEYDQKHKEL 253
ER +Q+ EL
Sbjct: 1699 SERARRHAEQERDEL 1713
Score = 69.1 bits (166), Expect = 6e-11
Identities = 66/308 (21%), Positives = 140/308 (45%), Gaps = 62/308 (20%)
Query: 8 EEIKRIKRELEELHNE-------KRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAR 60
++++ ++ ELE+ + K+ +E+ L++L+ ++ + RDE ++++L+ + +
Sbjct: 1596 KQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMK 1655
Query: 61 EF-------KAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLR----- 108
++ +A RDEI + KE +K + A++ L +E R Q R
Sbjct: 1656 DYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELAD 1715
Query: 109 ----------RLKMPKEKIEERIEKLEWEL---QTTPNISPEREKQIVDQIQVLATEL-- 153
L K ++E RI +LE EL Q+ + +R ++ Q+ L TEL
Sbjct: 1716 EIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAA 1775
Query: 154 ---------EIIQQIERYNN----KLQEVRKKIDQLKKAR-RAISMEIQQLANQSQQ--- 196
QQ+ER N KLQE+ + KA A+ +I QL Q +Q
Sbjct: 1776 ERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAK 1835
Query: 197 -----------FHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILE 245
+++ + + + ++ ++ AD+Y +++ + ++++++R+L E E +
Sbjct: 1836 ERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATR 1895
Query: 246 YDQKHKEL 253
+ ++L
Sbjct: 1896 ANASRRKL 1903
>pir||B70356 chromosome assembly protein homolog - Aquifex aeolicus
>gi|2983243|gb|AAC06839.1| (AE000699) chromosome
assembly protein homolog [Aquifex aeolicus]
Length = 1156
Score = 76.1 bits (184), Expect = 4e-13
Identities = 63/260 (24%), Positives = 131/260 (50%), Gaps = 23/260 (8%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
+E +RI EL L +I +++E +KELN + E N ++ +EK +F A+ +
Sbjct: 241 KERERILNELSSLRESLEDITFQIQENEKELNERERLLKEVNEKIMPFKEKVGKFTAEIE 300
Query: 68 EINQRIKELK----------KNRDEINAKL----DLLYQEA----LEYRTKRDEFRQLRR 109
+ IKE + KN +E+ L + L +E LE ++E++ L+
Sbjct: 301 NAERSIKEKERELKESENRVKNLEELINNLLSDKENLEREVGTLQLELEKLKEEYKSLKE 360
Query: 110 LKMPK-EKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYN--NKL 166
++ K ++EE E+L+ + E+EK + +++ L E + ++ I+R N NK+
Sbjct: 361 VEREKLRELEEEEERLKITFDEVKKLEEEKEK-LTEKLNSLNKEKQELE-IQRANLKNKI 418
Query: 167 QEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELR 226
+ +++ I++L R EI++ + ++ K ++ + +E + Y +++ E+R
Sbjct: 419 ERIKEDINKLISEREEKIKEIKEKEQEIKRLKAIKKKEEEELRNLTQELNIYEKRLSEVR 478
Query: 227 EKIREVRRELREIERKILEY 246
+K+ EV +E IER++ +
Sbjct: 479 KKLEEVLKEKGAIEREVRSF 498
Score = 73.7 bits (178), Expect = 2e-12
Identities = 74/320 (23%), Positives = 153/320 (47%), Gaps = 37/320 (11%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRL-REKAR 60
++K +K ++ + L ++K N+E ++ LQ EL +K E+ +K + REK R
Sbjct: 312 ELKESENRVKNLEELINNLLSDKENLEREVGTLQLEL----EKLKEEYKSLKEVEREKLR 367
Query: 61 EFKAKRDEIN---QRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKI 117
E + + + + +K+L++ ++++ KL+ L +E E +R LK E+I
Sbjct: 368 ELEEEEERLKITFDEVKKLEEEKEKLTEKLNSLNKEKQELEIQR------ANLKNKIERI 421
Query: 118 EERIEKLEWELQTTPNISPEREKQIVDQIQVLATELE----IIQQIERYNNKLQEVRKKI 173
+E I KL E + E+E++I + E E + Q++ Y +L EVRKK+
Sbjct: 422 KEDINKLISEREEKIKEIKEKEQEIKRLKAIKKKEEEELRNLTQELNIYEKRLSEVRKKL 481
Query: 174 DQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVEL----REKI 229
+++ K + AI E++ ++ S F + + Y E+ + + H +E+ R K
Sbjct: 482 EEVLKEKGAIEREVRSFSDVSDVF-KDIKGVYGSVSELIRVKNPEHITAIEVAGGGRLKF 540
Query: 230 -----REVRRELREIERKI----LEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALE-- 278
EV +E ++ +++ + ++ + + + R K V+F AV +E
Sbjct: 541 IVVEDEEVAKECIQLAKRMNLGRFSFIPLNRVRVEERPLRYPRTKGAVDF--AVNLVEYD 598
Query: 279 -KFKRGEKLTYDEILLLQRY 297
KF++ K + + L+++ +
Sbjct: 599 PKFEKVVKFVFGDTLIVENF 618
Score = 71.0 bits (171), Expect = 1e-11
Identities = 58/240 (24%), Positives = 129/240 (53%), Gaps = 25/240 (10%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
E ++ +RE ++ + IE L E+++ELN +K E++ L ++ +E + +R+
Sbjct: 778 EGVEEKRREYSKVRKQVSEIEKSLNEIERELN-------KKTYELEYLEKEIQEKERERE 830
Query: 68 EINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWE 127
+ +RIK LKK + + +L++E K E + +K KE++E+ I L+ +
Sbjct: 831 YLTERIKSLKKEIENL-----ILFKEKTLQEVKEAEVKVYDYIKQ-KEELEKEILNLKSK 884
Query: 128 LQTTPNISPEREKQIVDQ---IQVLATELE-IIQQIERYNN-KLQEVRKKIDQLKKARRA 182
L E +++I ++ ++VL ++E + ++++ Y + KL + I +LK+ +
Sbjct: 885 LGKLKIKEEELKEKIFEKEKNLKVLEEKIENLNEELKEYEDLKLGADEESIPKLKEKLKR 944
Query: 183 ISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERK 242
++ EIQ+L + + + E A+E+K+ ++Y +K +L+E+ + +++ + E E K
Sbjct: 945 VTEEIQKLGSVNFRAEEDY------AEELKR-FNDYKEKQQKLKEESKAIKKLIEETENK 997
>pir||F71190 probable chromosome assembly protein - Pyrococcus horikoshii
>gi|3258234|dbj|BAA30917.1| (AP000007) 1179aa long
hypothetical chromosome assembly protein [Pyrococcus
horikoshii]
Length = 1179
Score = 76.1 bits (184), Expect = 4e-13
Identities = 59/305 (19%), Positives = 152/305 (49%), Gaps = 33/305 (10%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDE 68
E+ ++ +L+ L N+ + +++ +++KE+++ + ++ E + LR + + + K E
Sbjct: 683 EVNSLRVKLKALENQSFELRIRMSDVEKEISLISKDLEKLIKEEESLRSEIEDSERKIAE 742
Query: 69 INQRIKELKKNRDEINAKLDLL------YQEALEYRTKRDEFRQLRRLKMPKEKIEERIE 122
I++ I + K ++ +++ L ++ALE R+ ++R ++ K+ E +
Sbjct: 743 IDETISKKKDEVAKLKGRIERLEKRRDKLKKALENPEAREVTEKIREVEREIAKLREELS 802
Query: 123 KLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRA 182
++E +L++ ++ D++ LE ++IE NK+ ++ I++ ++A ++
Sbjct: 803 RVEGKLESL-------NSRLNDELIPRKASLE--EEIEGLVNKINALKANINENEEALKS 853
Query: 183 ISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERK 242
++ ++++L + + Y + +E KK+ +E +KV ELRE+ ++ R ++E+ +
Sbjct: 854 LTEKLEKLKKEEGEI-------YSRIEEQKKKKEELERKVAELREEKEKISRRIQELRIE 906
Query: 243 ILEYDQKHKELIAYKLVARMRAKRDVNFEKAV--------QALEKFKRGEKLTYDEILLL 294
+ ++ +L + + + K +F K V LE K+ + +EI L
Sbjct: 907 VNTLKVRNSQLKSLLMEKNSQLK---HFSKEVIKSIRDIPSDLEGLKKEIEKMEEEIKAL 963
Query: 295 QRYNL 299
+ N+
Sbjct: 964 EPVNM 968
Score = 72.6 bits (175), Expect = 5e-12
Identities = 56/252 (22%), Positives = 123/252 (48%), Gaps = 11/252 (4%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELN-IWVQKRDEKNLEVKRLREKAREFKAKR 66
E+I+ ++RE+ +L E +E KLE L LN + ++ E++ L K KA
Sbjct: 785 EKIREVEREIAKLREELSRVEGKLESLNSRLNDELIPRKASLEEEIEGLVNKINALKANI 844
Query: 67 DEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEF-RQLRRLKMPKEKIEERIEKLE 125
+E + +K L + +++ + +Y E + K++E R++ L+ KEKI RI++L
Sbjct: 845 NENEEALKSLTEKLEKLKKEEGEIYSRIEEQKKKKEELERKVAELREEKEKISRRIQELR 904
Query: 126 WELQTTPNISPEREKQIVDQ-IQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAIS 184
E+ T + + + ++++ Q+ E+I+ I + L+ ++K+I+++++ +A+
Sbjct: 905 IEVNTLKVRNSQLKSLLMEKNSQLKHFSKEVIKSIRDIPSDLEGLKKEIEKMEEEIKALE 964
Query: 185 MEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKIL 244
+ + + ++ K + ++ E D + E I E+ +E + + K
Sbjct: 965 PVNMKAIEDFEVVERRYLELKSKRERLEAEKD-------SIIEFINEIEKEKKNVFMKTF 1017
Query: 245 EYDQKH-KELIA 255
+ K+ EL A
Sbjct: 1018 DAIAKNFSELFA 1029
Score = 69.5 bits (167), Expect = 4e-11
Identities = 61/288 (21%), Positives = 135/288 (46%), Gaps = 40/288 (13%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
+EI I ++LE+L E+ ++ ++E+ ++++ + +K EV +L+ + + +RD
Sbjct: 710 KEISLISKDLEKLIKEEESLRSEIEDSERKIAEIDETISKKKDEVAKLKGRIERLEKRRD 769
Query: 68 ------------EINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKE 115
E+ ++I+E+++ ++ +L + + LE R + R +E
Sbjct: 770 KLKKALENPEAREVTEKIREVEREIAKLREELSRV-EGKLESLNSRLNDELIPRKASLEE 828
Query: 116 KIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATEL-EIIQQIERYNNKLQEVRKKID 174
+IE + K+ L+ N + E K + ++++ L E EI +IE K +E+ +K+
Sbjct: 829 EIEGLVNKIN-ALKANINENEEALKSLTEKLEKLKKEEGEIYSRIEEQKKKKEELERKVA 887
Query: 175 QLKKARRAISMEIQQLA---------------------NQSQQFHEQMIKTYQKA----D 209
+L++ + IS IQ+L +Q + F +++IK+ + +
Sbjct: 888 ELREEKEKISRRIQELRIEVNTLKVRNSQLKSLLMEKNSQLKHFSKEVIKSIRDIPSDLE 947
Query: 210 EVKKEADEYHQKVVELREKIREVRRELREIERKILEYDQKHKELIAYK 257
+KKE ++ +++ L + + +ER+ LE K + L A K
Sbjct: 948 GLKKEIEKMEEEIKALEPVNMKAIEDFEVVERRYLELKSKRERLEAEK 995
>gb|AAK42417.1| Purine NTPase [Sulfolobus solfataricus]
Length = 864
Score = 75.7 bits (183), Expect = 6e-13
Identities = 67/279 (24%), Positives = 142/279 (50%), Gaps = 26/279 (9%)
Query: 16 ELEELHNEKRNIELKLEELQKEL-NIWVQKRDEKNLE--VKRLREKAREFKAKRDEINQR 72
++E L +EK I + +++ E + + DE++ + +K + + + ++E+ +
Sbjct: 403 KVESLISEKNEIINNISQVEGETCPVCGRPLDEEHKQKIIKEAKSYILQLELNKNELEE- 461
Query: 73 IKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWELQTTP 132
ELKK +E+N K++ Y+ + D +R+LK K+ E IE L E+++
Sbjct: 462 --ELKKITNELN-KIEREYRRLSNNKASYDNV--MRQLK----KLNEEIENLHSEIESLK 512
Query: 133 NISPEREKQIVDQIQVLATELEIIQQIERYNNK-LQEVRKKIDQLKKARRAISMEIQQLA 191
NI E K+I ++++ L E ++ +Y + L + R K+D++KK + I E++ L
Sbjct: 513 NID-EEIKKINEEVKELKLYYEEFMRLSKYTKEELDKKRVKLDEMKKKKEEIEKEMRGLE 571
Query: 192 NQSQQFHEQMIKTY--------QKADEVKKEA---DEYHQKVVELREKIREVRRELREIE 240
++ + + +++ K DE+KK+ ++Y ++V L+E+++ +R E+ I+
Sbjct: 572 SELKGLDRKALESKILDLENKRVKLDEMKKKKGILEDYIRQVKLLQEEVKNLREEVNIIQ 631
Query: 241 RKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEK 279
Y++ L AY L + + R E +++LEK
Sbjct: 632 FDENRYNELKTSLDAYNLSLKEKENRKSRIEGELESLEK 670
Score = 71.0 bits (171), Expect = 1e-11
Identities = 70/325 (21%), Positives = 153/325 (46%), Gaps = 36/325 (11%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEV---KRLREKAREFKA 64
E+ R K ELE + + + +E KLEELQ + +++ + + + ++ +RL + A E
Sbjct: 316 EKAIRRKEELEPKYLKYKELERKLEELQPKYQQYLKLKSDLDSKLNLKERLEKDASELSN 375
Query: 65 KRDEIN---QRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMP-------- 113
D++N Q+++E +K + + A+L + E + Q+ P
Sbjct: 376 DIDKVNSLEQKVEETRKKQLNLRAQLAKVESLISEKNEIINNISQVEGETCPVCGRPLDE 435
Query: 114 --KEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELE-----------IIQQIE 160
K+KI + + +L+ N E K+I +++ + E +++Q++
Sbjct: 436 EHKQKIIKEAKSYILQLELNKNELEEELKKITNELNKIEREYRRLSNNKASYDNVMRQLK 495
Query: 161 RYNNKLQEVRKKIDQLKKAR---RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADE 217
+ N +++ + +I+ LK + I+ E+++L ++F T ++ D+ + + DE
Sbjct: 496 KLNEEIENLHSEIESLKNIDEEIKKINEEVKELKLYYEEFMRLSKYTKEELDKKRVKLDE 555
Query: 218 YHQKVVELREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQAL 277
+K E+ +++R + EL+ ++RK LE E KL M+ K+ + E ++ +
Sbjct: 556 MKKKKEEIEKEMRGLESELKGLDRKALESKILDLENKRVKL-DEMKKKKGI-LEDYIRQV 613
Query: 278 EKFKRGEKLTYDEILLLQ----RYN 298
+ + K +E+ ++Q RYN
Sbjct: 614 KLLQEEVKNLREEVNIIQFDENRYN 638
>gi|11499153 chromosome segregation protein (smc1) [Archaeoglobus fulgidus]
>gi|7446602|pir||E69444 chromosome segregation protein
(smc1) homolog - Archaeoglobus fulgidus
>gi|2649004|gb|AAB89690.1| (AE000995) chromosome
segregation protein (smc1) [Archaeoglobus fulgidus]
Length = 1156
Score = 75.7 bits (183), Expect = 6e-13
Identities = 50/216 (23%), Positives = 118/216 (54%), Gaps = 7/216 (3%)
Query: 43 QKRDEKNLEVKRLREKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRD 102
+K+++ E++R+RE + +A E+N R++ L+++R+E ++L ++ EY
Sbjct: 163 EKKEKALEELERVRESIEKLEAVIAEVNDRLQTLERDRNEAIRYKEILSKKE-EYEGYLR 221
Query: 103 EFRQLRRLKMPKEKIEERIEKLEWELQTTPNISPE---REKQIVDQIQVLATELEII--Q 157
L +K KEK+E +E+LE + + PE R ++ ++I LA ++ + +
Sbjct: 222 AHNYLTAVKS-KEKVERELERLERQKDELTSKIPEINARIAELNEKINELAAKISELGDE 280
Query: 158 QIERYNNKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADE 217
+ +++ E+ +++ L++A R E ++L +S + ++ K ++ + + E +E
Sbjct: 281 RSAEIQSRILELSSELESLRRAERFYLDEAKRLEEESVKIISEISKIKEEMESLDGELEE 340
Query: 218 YHQKVVELREKIREVRRELREIERKILEYDQKHKEL 253
Y K +++ E + E+ ++ + +++ E D+KH+EL
Sbjct: 341 YAIKRIQVGEIVDELAAKMELLRQRLEEVDKKHREL 376
Score = 71.8 bits (173), Expect = 9e-12
Identities = 63/242 (26%), Positives = 121/242 (49%), Gaps = 33/242 (13%)
Query: 9 EIKRIKRELEELHNE-KRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
E+ +I EL+++ E +RN E+ L ++K++ KR++ ++ + E K + D
Sbjct: 788 EVPKIVEELDKIKEEHQRNREI-LISIEKKIESLEFKREQLESSMQEKQVYLDEIKDRID 846
Query: 68 EINQRIKELKKNRDEINAKLDLLYQEALE-------YRTKRDE-FRQLRRLKMPKEKIEE 119
EI + I+E K +EIN++L+ L +E E R +RDE +QLR + K KIE
Sbjct: 847 EIRRTIEEGKARVEEINSELEELRKEERELGKELKGLRKERDELIKQLRNAEEEKRKIEA 906
Query: 120 RIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKA 179
I++LE ER K +++++ +E+ I ++ EV + + L+K
Sbjct: 907 EIDRLE-----------ERIKLQKERLEIAESEIAEIGEV--------EVPENLPPLEKV 947
Query: 180 RRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREI 239
+ + + +L+ F + +K Q+ +EVK DE +K + L ++ ++ + +
Sbjct: 948 EKVLDEVLVELST----FGDVNLKAIQEYEEVKARRDELVEKKMVLEKERADILDRIEKY 1003
Query: 240 ER 241
ER
Sbjct: 1004 ER 1005
>sp|P35580|MYSO_HUMAN MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B (CELLULAR MYOSIN HEAVY CHAIN,
TYPE B) (NMMHC-B) >gi|11276948|pir||A59252 myosin heavy
chain, nonmuscle, form IIB - human
>gi|641958|gb|AAA99177.1| (M69181) non-muscle myosin B
[Homo sapiens]
Length = 1976
Score = 74.5 bits (180), Expect = 1e-12
Identities = 54/255 (21%), Positives = 122/255 (47%), Gaps = 20/255 (7%)
Query: 12 RIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQ 71
R E + E R E K L + L ++ ++E + K+LR + + +D++ +
Sbjct: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525
Query: 72 RIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKL----EW 126
+ EL+K++ + Q+ E RT+ +E +L+ + K ++E ++ + E
Sbjct: 1526 NVHELEKSKRALE-------QQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1578
Query: 127 ELQTTPNISPEREKQIVDQIQVLATELE--------IIQQIERYNNKLQEVRKKIDQLKK 178
+LQT + E+++ ++ Q++ L ELE + ++ L+++ +I+ K
Sbjct: 1579 DLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANK 1638
Query: 179 ARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELRE 238
AR + ++++L Q + + ++ + DE+ ++ E +K+ L +I +++ EL
Sbjct: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELAS 1698
Query: 239 IERKILEYDQKHKEL 253
ER +Q+ EL
Sbjct: 1699 SERARRHAEQERDEL 1713
>emb|CAA71688.1| (Y10687) purine NTPase [Sulfolobus acidocaldarius]
Length = 886
Score = 74.5 bits (180), Expect = 1e-12
Identities = 80/348 (22%), Positives = 165/348 (46%), Gaps = 57/348 (16%)
Query: 3 VKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRD---------------- 46
+K + EI R+K+E+EE+ + NIE + +E + ELN + + +
Sbjct: 191 LKREEAEIDRLKKEIEEIKVKLENIEREAKEKEDELNQYNTEFNRIKEIKVQYDILSGEL 250
Query: 47 ---EKNLEVKRLREKAREFKAKR-DEINQRIKELKKNRDEINA----KLDLLYQEAL--- 95
K +E LR K E K KR ++I +KEL +NR++IN K L+ ++L
Sbjct: 251 SVVNKKIEEIALRLKDFEEKEKRYNKIETEVKELDENREKINTISSFKSILVQIDSLKSQ 310
Query: 96 ------EYRTKRDEFRQLRRLKMPKEKIEERIEKLEWELQTTPNISPEREKQ---IVDQI 146
+ + K+++ ++ + L+ KEK E IEK + EL+ E EK+ ++ I
Sbjct: 311 INVVENDLKRKKEKLKRKKELE-EKEKQYEEIEKRKKELEEKEKQYEEIEKRLTYVLKNI 369
Query: 147 QVLATELEIIQQIERYN--NKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKT 204
+ E+E + ++ + NK+++V +I+Q+ + + L + EQ +K
Sbjct: 370 ERQKNEIEKLNYVDTQDLENKIKDVSDRINQIDNELKGLLDRRGDLNGRK----EQTLKI 425
Query: 205 YQKADEVK--------KEADEYHQKVV--ELREKIREVRRELREIERKILEYDQKHKELI 254
Y + ++ + D H+ + E++ ++ E+ +++ ++ +I ++ +EL
Sbjct: 426 YNNLNSIEDDRCPICGRPLDSEHKAKIREEIKVQLLELNKQITALQARINSLIKEREELE 485
Query: 255 A----YKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQRYN 298
A +L + R+K +E ++ L++ + + +EIL L Y+
Sbjct: 486 ATRNKLQLELQKRSKEKGIYEAKLKELQRLEEEKNKLQNEILSLLSYH 533
>pir||C71622 hypothetical protein PFB0145c - malaria parasite (Plasmodium
falciparum) >gi|3845107|gb|AAC71819.1| (AE001375)
hypothetical protein [Plasmodium falciparum]
Length = 1979
Score = 73.7 bits (178), Expect = 2e-12
Identities = 56/261 (21%), Positives = 127/261 (48%), Gaps = 19/261 (7%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKARE 61
Q+KV EIK +K ELE+ E ++IE +E E+N + + +EK ++ + +E
Sbjct: 411 QLKVYKCEIKNLKTELEKKEKELKDIENVSKE---EINKLINQLNEKEKQILAFNKNHKE 467
Query: 62 -FKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIE-- 118
++E+ + +K K E+ +D+ +E + + K + + +++ K++ E
Sbjct: 468 EIHGLKEELKESVKITKIETQELQEMVDIKQKELDQLQEKYNAQIESISIELSKKEKEYN 527
Query: 119 -------ERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRK 171
E I L +L+ T + ++I +L ++ ++ N ++ +
Sbjct: 528 QYKNTYIEEINNLNEKLEETNKEYTNLQNNYTNEINMLNNDIHML------NGNIKTMNT 581
Query: 172 KIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIRE 231
+I LK ++ +I +L N+ + ++ + + ++K+E D + ++V+L +I
Sbjct: 582 QISTLKNDVHLLNEQIDKLNNEKGTLNSKISELNVQIMDLKEEKDFLNNQIVDLSNQIDL 641
Query: 232 VRRELREIERKILEYDQKHKE 252
+ R++ E E K+LE + K+K+
Sbjct: 642 LTRKMEEKENKMLEQENKYKQ 662
Score = 73.4 bits (177), Expect = 3e-12
Identities = 59/268 (22%), Positives = 124/268 (46%), Gaps = 33/268 (12%)
Query: 3 VKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREF 62
VK E I + + E + + +E +LEE K++++ ++ EK E +R +EK RE
Sbjct: 291 VKEKNETINSLNDNIIEKEKKYKLLEYELEEKNKQIDLLNKQEKEKEKEKEREKEKERE- 349
Query: 63 KAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEF------------------ 104
K K E + IKELK + I K+ + ++ + F
Sbjct: 350 KEKEKEYDTLIKELKDEKISILEKVHSIKVREMDIEKREHNFLHMEDQLKDLKNSFVKNN 409
Query: 105 RQLRRLKMPKEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNN 164
QL+ K + ++ +EK E EL+ N+S E ++++Q+ E +I+ + +
Sbjct: 410 NQLKVYKCEIKNLKTELEKKEKELKDIENVSKEEINKLINQLN--EKEKQILAFNKNHKE 467
Query: 165 KLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQK-----ADEVKKEADEYH 219
++ +++++ + K + + E+Q++ + Q+ +Q+ + Y + E+ K+ EY+
Sbjct: 468 EIHGLKEELKESVKITKIETQELQEMVDIKQKELDQLQEKYNAQIESISIELSKKEKEYN 527
Query: 220 Q-------KVVELREKIREVRRELREIE 240
Q ++ L EK+ E +E ++
Sbjct: 528 QYKNTYIEEINNLNEKLEETNKEYTNLQ 555
>pir||B75150 chromosome segregation protein (smc1) PAB2109 - Pyrococcus abyssi
(strain Orsay) >gi|5457791|emb|CAB49281.1| (AJ248284)
chromosome segregation protein (smc1) [Pyrococcus
abyssi]
Length = 1177
Score = 73.7 bits (178), Expect = 2e-12
Identities = 71/294 (24%), Positives = 133/294 (45%), Gaps = 28/294 (9%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDE----KNLEVKRLRE 57
++K EIK +E++ E + IE KLEE+ KE+ V+K E + L K E
Sbjct: 235 EIKKVESEIKGNDERIEKIEEEIKEIEEKLEEIAKEI---VRKERELKEVEELIEKESSE 291
Query: 58 KAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQ-LRRLKMPKEK 116
+A + + E+N +I K+N + +LD + + +DE ++ L ++ K
Sbjct: 292 EALKITREIGEVNSKINLAKRNIEVAKKELD---EAQIRLIKAKDELKKVLSEIEKSKGA 348
Query: 117 IEERIEKLEWELQTTPNISPEREKQIV-----DQIQVLATEL--EIIQQIERYNNKLQEV 169
I ++ E L + ER K +V D+ +A E +++++E L E
Sbjct: 349 IARWGKRKEALLNKIKELEEERNKLVVKLGEIDRTFAVAREEFDNVVKELENARKSLYEN 408
Query: 170 RKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKI 229
I +L+ + +S I L + E++ K +K +E K E K+ + ++
Sbjct: 409 EADIKRLEAEKERLSSRITILKAKLPGIREEVEKLREKLEEKKAELSNVENKISSISQRR 468
Query: 230 REVRRELR----EIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEK 279
R+V EL E+++ E + +ELI + A+ +V +AV+ L++
Sbjct: 469 RKVEEELEKKTSELQKVSSELESLERELI------KAEAQSEVRVNRAVEELKR 516
Score = 73.4 bits (177), Expect = 3e-12
Identities = 62/257 (24%), Positives = 128/257 (49%), Gaps = 14/257 (5%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
+EI + R++E+L +E+R I+ ++E+ QK + + EK E+ +LR K + KRD
Sbjct: 710 KEITLLTRDIEKLLSEERIIKSEIEDSQKGIEEIDRIIHEKKGEIAKLRGKIERLERKRD 769
Query: 68 EI-----NQRIKELKKNRDEINAKLDLLYQE--ALEYRTKRDEFRQLRRLKMPKEKIEER 120
++ N +E+ + E+ ++ L +E +E R + R L K +EE
Sbjct: 770 KLKKALENPEAREVTEKIREVEGEIGKLREELSRVESRLESLNSRLNEELIPRKASLEEE 829
Query: 121 IEKLEWELQT-TPNISPERE--KQIVDQIQVL-ATELEIIQQIERYNNKLQEVRKKIDQL 176
IE L ++ NI+ E K + +++ L A E + +I Y K +E+ K+I +L
Sbjct: 830 IEGLVNKINALKANIAENEEVLKGLKGKLEELKAKEESVHSKISEYRRKREELEKEIREL 889
Query: 177 KKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRREL 236
+K + +S +Q+ ++ + + +E + + ++V+ IRE+ +L
Sbjct: 890 RKEKEELSKRMQEFRIEANTLRVRNTQLRSILNEKNSQLRHFPKEVI---RSIREIPLDL 946
Query: 237 REIERKILEYDQKHKEL 253
+++R+I E +++ + L
Sbjct: 947 EKLKREIEEMEEEIRSL 963
Score = 72.6 bits (175), Expect = 5e-12
Identities = 58/253 (22%), Positives = 127/253 (49%), Gaps = 13/253 (5%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNI-WVQKRDEKNLEVKRLREKAREFKAKR 66
E+I+ ++ E+ +L E +E +LE L LN + ++ E++ L K KA
Sbjct: 785 EKIREVEGEIGKLREELSRVESRLESLNSRLNEELIPRKASLEEEIEGLVNKINALKANI 844
Query: 67 DEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEF-RQLRRLKMPKEKIEERIEKLE 125
E + +K LK +E+ AK + ++ + EYR KR+E +++R L+ KE++ +R+++
Sbjct: 845 AENEEVLKGLKGKLEELKAKEESVHSKISEYRRKREELEKEIRELRKEKEELSKRMQEFR 904
Query: 126 WELQTTPNISPEREKQIVDQ--IQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAI 183
E T + + + I+++ Q+ E+I+ I L++++++I+++++
Sbjct: 905 IEANTL-RVRNTQLRSILNEKNSQLRHFPKEVIRSIREIPLDLEKLKREIEEMEE----- 958
Query: 184 SMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKI 243
EI+ L + + E ++ E+K + ++ + + E I E+ +E + + +
Sbjct: 959 --EIRSLEPVNMKAIEDFEVVERRYLELKSKREKLEAEKESIIEFINEIEKEKKNVFMRT 1016
Query: 244 LEYDQKH-KELIA 255
E K+ EL A
Sbjct: 1017 FEAIAKNFSELFA 1029
Score = 71.8 bits (173), Expect = 9e-12
Identities = 62/303 (20%), Positives = 150/303 (49%), Gaps = 29/303 (9%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDE 68
EI +K EL L N+ + +K+ E++KE+ + + ++ E + ++ + + + +E
Sbjct: 683 EINSLKVELRGLENQGFELRIKMSEIEKEITLLTRDIEKLLSEERIIKSEIEDSQKGIEE 742
Query: 69 INQRIKELKKNRDEINAKLDLL------YQEALEYRTKRDEFRQLRRLKMPKEKIEERIE 122
I++ I E K ++ K++ L ++ALE R+ ++R ++ K+ E +
Sbjct: 743 IDRIIHEKKGEIAKLRGKIERLERKRDKLKKALENPEAREVTEKIREVEGEIGKLREELS 802
Query: 123 KLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRA 182
++E L++ + E +++ + + ++IE NK+ ++ I + ++ +
Sbjct: 803 RVESRLESLNSRLNE---------ELIPRKASLEEEIEGLVNKINALKANIAENEEVLKG 853
Query: 183 ISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIE-- 240
+ ++++L + + H ++ + +K +E++KE E ++ EL ++++E R E +
Sbjct: 854 LKGKLEELKAKEESVHSKISEYRRKREELEKEIRELRKEKEELSKRMQEFRIEANTLRVR 913
Query: 241 ----RKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQR 296
R IL ++K+ +L + +R+ R++ + LEK KR + +EI L+
Sbjct: 914 NTQLRSIL--NEKNSQLRHFPKEV-IRSIREIPLD-----LEKLKREIEEMEEEIRSLEP 965
Query: 297 YNL 299
N+
Sbjct: 966 VNM 968
>gb|AAF61445.1|AF139055_1 (AF139055) nonmuscle myosin heavy chain-B [Rattus norvegicus]
Length = 1976
Score = 73.7 bits (178), Expect = 2e-12
Identities = 54/255 (21%), Positives = 122/255 (47%), Gaps = 20/255 (7%)
Query: 12 RIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQ 71
R E + E R E K L + L ++ ++E + K+LR + + +D++ +
Sbjct: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525
Query: 72 RIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKL----EW 126
+ EL+K++ + Q+ E RT+ +E +L+ + K ++E ++ + E
Sbjct: 1526 NVHELEKSKRALE-------QQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1578
Query: 127 ELQTTPNISPEREKQIVDQIQVLATELE--------IIQQIERYNNKLQEVRKKIDQLKK 178
+LQT + E+++ ++ Q++ L ELE + ++ L+++ +I+ K
Sbjct: 1579 DLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANK 1638
Query: 179 ARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELRE 238
AR + ++++L Q + + ++ + DE+ ++ E +K+ L +I +++ EL
Sbjct: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELAS 1698
Query: 239 IERKILEYDQKHKEL 253
ER +Q+ EL
Sbjct: 1699 SERARRHAEQERDEL 1713
Score = 69.1 bits (166), Expect = 6e-11
Identities = 66/308 (21%), Positives = 140/308 (45%), Gaps = 62/308 (20%)
Query: 8 EEIKRIKRELEELHNE-------KRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAR 60
++++ ++ ELE+ + K+ +E+ L++L+ ++ + RDE ++++L+ + +
Sbjct: 1596 KQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMK 1655
Query: 61 EF-------KAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLR----- 108
++ +A RDEI + KE +K + A++ L +E R Q R
Sbjct: 1656 DYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELAD 1715
Query: 109 ----------RLKMPKEKIEERIEKLEWEL---QTTPNISPEREKQIVDQIQVLATEL-- 153
L K ++E RI +LE EL Q+ + +R ++ Q+ L TEL
Sbjct: 1716 EIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAA 1775
Query: 154 ---------EIIQQIERYNN----KLQEVRKKIDQLKKAR-RAISMEIQQLANQSQQ--- 196
QQ+ER N KLQE+ + KA A+ +I QL Q +Q
Sbjct: 1776 ERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAK 1835
Query: 197 -----------FHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILE 245
+++ + + + ++ ++ AD+Y +++ + ++++++R+L E E +
Sbjct: 1836 ERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATR 1895
Query: 246 YDQKHKEL 253
+ ++L
Sbjct: 1896 ANASRRKL 1903
>gb|AAC72233.1| (AF092090) cp151 [Rattus norvegicus]
Length = 751
Score = 73.4 bits (177), Expect = 3e-12
Identities = 53/254 (20%), Positives = 123/254 (47%), Gaps = 10/254 (3%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDE 68
+++++++E E E++N +L EL ELN ++ E L++ E + K DE
Sbjct: 488 QLQKLQKESSETEEERKNNRQQLLELSSELNEGQRRLSSAEKEKSLLQKTLDEEEKKIDE 547
Query: 69 INQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKLEWE 127
+ K ++ + E+ L L E E + +E R QLR+ K ++ +EE IE L E
Sbjct: 548 LLHGAKVSEQKQRELTNSLSKLQDELAETKRLLEEKREQLRKSKDQEKALEEEIEALRQE 607
Query: 128 LQTTPNISPEREKQIVDQIQVLATEL-----EIIQQIERYNNK---LQEVRKKIDQLKKA 179
+ ++ E+ +++ ++ + L EL ++ I +YNN +QE+ +I + K +
Sbjct: 608 SKKKEKMAKEQLRKLEEEKENLQAELSSCSSQLDSSINKYNNSQKVIQELNTEIARQKDS 667
Query: 180 RRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREI 239
+ ++ + + + M+ + + +E+ +++ + + EK+ + E + +
Sbjct: 668 IMILQTQLDSAIQKEKNCFQNMV-SKETYEELLRKSGTCQDDLTQALEKLTQATSETKSL 726
Query: 240 ERKILEYDQKHKEL 253
+R + + ++ +L
Sbjct: 727 QRNLQQTQERKAQL 740
>gb|AAK41222.1| Hypothetical protein [Sulfolobus solfataricus]
Length = 298
Score = 73.0 bits (176), Expect = 4e-12
Identities = 70/311 (22%), Positives = 153/311 (48%), Gaps = 51/311 (16%)
Query: 3 VKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKA--- 59
+ D +E+ + EL+E + ++L+L E K++ +KR EK +VK L ++
Sbjct: 4 ISADTDELYKKISELKENIVRLKQLKLELIEKVKKMR---EKRREKIAKVKELTQQINVV 60
Query: 60 -REFKAKRDEINQRIKELKKNRDEINAKLDLLYQE-------------ALEYRTKRDEFR 105
+E+K K +E NQ +KE +KN EI ++ ++E ++E + + E++
Sbjct: 61 RQEYKMKLEEFNQ-LKERRKNLIEIIQQIRKDFEEVKKLSSNNLGNPDSIERKIRELEWK 119
Query: 106 -QLRRLKMPKEK-IEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYN 163
Q L + +EK + +RI +LE +LQ I +EK+ ++ ++LA ++E+ ER
Sbjct: 120 LQTSSLTLEEEKKVIQRIAELEKKLQDAKKIMKIKEKRTEEKAELLAKKVELNTIRERIK 179
Query: 164 NKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVV 223
+ E+ +K + +KK L + + +++ + + + K+ +E + ++
Sbjct: 180 TLINEITEKKNIIKK-----------LVEERNKLRDEINGLNNEIENISKQIEELNVEIK 228
Query: 224 ELREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRG 283
++ E +R L+ ++ ++ + E I K +K+++ EK K+
Sbjct: 229 NKSNELNEAQRALKSLQENPVQVNT--TEFIEKK-------------KKSIE--EKLKQN 271
Query: 284 EKLTYDEILLL 294
++L+++E L+L
Sbjct: 272 KRLSFEEFLIL 282
>gb|AAF07789.1|AC010704_14 (AC010704) hypothetical protein; 57314-54712 [Arabidopsis thaliana]
Length = 779
Score = 73.0 bits (176), Expect = 4e-12
Identities = 66/291 (22%), Positives = 138/291 (46%), Gaps = 25/291 (8%)
Query: 16 ELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIKE 75
E+E L + + +E KLE+L+ E + E EVK RE+A + + R KE
Sbjct: 344 EIEVLTSRIKELEEKLEKLEAE-------KHELENEVKCNREEAVVHIENSEVLTSRTKE 396
Query: 76 LKKNRDEINAKLDLLYQEALEYRTK------RDEFRQLRRLKMPKEKIEERIEKLEWE-L 128
L++ +++ A+ + L E R K ++ L +++EE++EKLE E +
Sbjct: 397 LEEKLEKLEAEKEELKSEVKCNREKAVVHVENSLAAEIEVLTSRTKELEEQLEKLEAEKV 456
Query: 129 QTTPNISPEREKQIVDQIQVLATELEIIQ-QIERYNNKLQEVRKKIDQLK-------KAR 180
+ + RE+ + LATE+E++ +I++ KL+++ + D+LK +
Sbjct: 457 ELESEVKCNREEAVAQVENSLATEIEVLTCRIKQLEEKLEKLEVEKDELKSEVKCNREVE 516
Query: 181 RAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIE 240
+ E++ +A + + ++ K + E++ D K E + ++E+ +L EI+
Sbjct: 517 STLRFELEAIACEKMELENKLEKLEVEKAELQISFDIIKDKYEESQVCLQEIETKLGEIQ 576
Query: 241 RKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEI 291
++ ++ E+ + + AK +++LE+ R E+ +DE+
Sbjct: 577 TEMKLVNELKAEVESQTIAMEADAKTK---SAKIESLEEDMRKERFAFDEL 624
>dbj|BAB06206.1| (AP001515) chromosome segregation SMC protein [Bacillus halodurans]
Length = 1188
Score = 73.0 bits (176), Expect = 4e-12
Identities = 63/284 (22%), Positives = 131/284 (45%), Gaps = 31/284 (10%)
Query: 4 KVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFK 63
+++ EI + +++ +H E + L+ L+++ Q+ EK V+ L+++ +
Sbjct: 221 ELEQVEIAVLVYDIDRIHTEWNKAKEALDLLKEQHRALEQQISEKEQSVQGLKQQIAQLD 280
Query: 64 AKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEK 123
+ Q++ + ++ + D+L + R++ Q R + EE++
Sbjct: 281 EEAQIAQQQLLSASETLEKREGRRDVLKERLKNAAENREQLLQTIR------EGEEKVAS 334
Query: 124 LEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAI 183
L+ L + E E + Q+ A E EI Q + + +E+ + +D+LK +
Sbjct: 335 LKVHL------AKEEEAKQKAYEQMTALEAEIRNQEKALHGNEKELEETVDRLKSDYIEL 388
Query: 184 SMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVEL-------------REK-- 228
E L N+++ EQ+ + QK + + +E + Y QK EL +EK
Sbjct: 389 LNEQASLRNETRYLEEQLQQLQQKQERLIRENEAYFQKRKELEAQEEQERMQFEAKEKQL 448
Query: 229 ---IREVRRELREIERKILEYDQKHKELI-AYKLVARMRAKRDV 268
+ E R + R++E+ Y+QK K+L AY+L+ R+ +++DV
Sbjct: 449 HRLVDEYRNQQRKVEQVTRVYEQKEKQLYEAYQLIQRLTSRKDV 492
>gi|4502781 centromere protein E; Centromere autoantigen E (312kD) [Homo sapiens]
>gi|399227|sp|Q02224|CENE_HUMAN CENTROMERIC PROTEIN E
(CENP-E PROTEIN) >gi|284038|pir||S28261 centromere
protein E - human >gi|29865|emb|CAA78727.1| (Z15005)
CENP-E [Homo sapiens]
Length = 2663
Score = 72.2 bits (174), Expect = 7e-12
Identities = 70/289 (24%), Positives = 126/289 (43%), Gaps = 37/289 (12%)
Query: 1 MQVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKR------ 54
+ V+ + E+++ E+E L NE +N EL LE ++ E QK +E EVK
Sbjct: 1144 LNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERK 1203
Query: 55 -LREKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQ------- 106
L+E + F+ +RD + I+E++ + +L + + E++ DE R+
Sbjct: 1204 VLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTA 1263
Query: 107 ----LRRLKMPKEKIEERIEKLEWELQTTPNISPEREKQ-IVDQIQVL---------ATE 152
+ L+ K++E I L E + PN+ E Q ++++++L T
Sbjct: 1264 QIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTL 1323
Query: 153 LEIIQQIERYNNKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVK 212
I + R N K QE +++I L K R + + L + Q E + +T K E +
Sbjct: 1324 ARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQ 1383
Query: 213 ---------KEADEYHQKVVELREKIREVRRELREIERKILEYDQKHKE 252
KE D K+V E+ + L IE ++L ++ +E
Sbjct: 1384 SKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQE 1432
>prf||1819485A CENP-E protein [Homo sapiens]
Length = 2663
Score = 72.2 bits (174), Expect = 7e-12
Identities = 70/289 (24%), Positives = 126/289 (43%), Gaps = 37/289 (12%)
Query: 1 MQVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKR------ 54
+ V+ + E+++ E+E L NE +N EL LE ++ E QK +E EVK
Sbjct: 1144 LNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERK 1203
Query: 55 -LREKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQ------- 106
L+E + F+ +RD + I+E++ + +L + + E++ DE R+
Sbjct: 1204 VLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTA 1263
Query: 107 ----LRRLKMPKEKIEERIEKLEWELQTTPNISPEREKQ-IVDQIQVL---------ATE 152
+ L+ K++E I L E + PN+ E Q ++++++L T
Sbjct: 1264 QIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTL 1323
Query: 153 LEIIQQIERYNNKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVK 212
I + R N K QE +++I L K R + + L + Q E + +T K E +
Sbjct: 1324 ARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQ 1383
Query: 213 ---------KEADEYHQKVVELREKIREVRRELREIERKILEYDQKHKE 252
KE D K+V E+ + L IE ++L ++ +E
Sbjct: 1384 SKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQE 1432
>pir||T47237 myosin II heavy chain [imported] - Naegleria fowleri (fragment)
>gi|1353761|gb|AAB01786.1| (U43192) myosin II heavy
chain [Naegleria fowleri]
Length = 746
Score = 72.2 bits (174), Expect = 7e-12
Identities = 61/303 (20%), Positives = 144/303 (47%), Gaps = 27/303 (8%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDE 68
++ +KR+L+E +N ++ ++++LQK+L+ R+E ++ LR++ +E ++ +
Sbjct: 305 DMNGLKRQLDESNNLVAKLKAEIQKLQKDLSDHHGDREETEEQLDALRKQLQELTSRLSD 364
Query: 69 INQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWEL 128
NQ+ ++ +R + ++ + L E R + D + RRLK E+++ E + EL
Sbjct: 365 ANQKTQQEAASRQNLESENNRLKSEV--SRLREDLQNENRRLKQEMERVQSESENEKSEL 422
Query: 129 QTTPNISPEREKQIVDQIQVL---------------ATELEIIQ-----QIERYNNKLQE 168
T E ++ D+++ L + E+E ++ Q+ + +++E
Sbjct: 423 LTQLQKLQEAYSEVKDELKDLSKNASRGGGVVGGVDSAEVEKLRREYEMQLAQLKARVEE 482
Query: 169 VRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREK 228
V ++ ++ +R++ M++ ++ + Q K Q+ V+ E DE EL E+
Sbjct: 483 VTQQRVDVENKKRSVEMDLTEMKTRLQTEERLRKKVEQQKKSVEMECDELR----ELAEE 538
Query: 229 IREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEK-AVQALEKFKRGEKLT 287
++R EL + + Q+ ++ + + +R A+ +K ++ L++ E+
Sbjct: 539 AEDLRDELNRTKLEHQALIQQLRQDLLQERHSRASAEESATRQKREIEELQQDLEQERAK 598
Query: 288 YDE 290
DE
Sbjct: 599 LDE 601
>gb|AAD46501.1|AF148805_6 (AF148805) latent nuclear antigen [Kaposi's sarcoma-associated
herpesvirus]
Length = 1129
Score = 71.8 bits (173), Expect = 9e-12
Identities = 52/247 (21%), Positives = 136/247 (55%), Gaps = 7/247 (2%)
Query: 6 DPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAK 65
+P++ + ++E ++ ++++ + + E+ Q E Q++DE+ + ++ E+ ++ + +
Sbjct: 580 EPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQ 639
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
+DE Q+ ++ ++ ++E + + E + ++DE +Q + + +++ +E+ ++ E
Sbjct: 640 QDE--QQQQDEQEQQEEQEQQEEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDE 697
Query: 126 WELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAISM 185
E Q E+E+Q +Q Q E E+ +Q + + QE+ ++ +L++ + +
Sbjct: 698 QEQQEEQEQQEEQEQQ-EEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEE 756
Query: 186 EIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILE 245
+ Q+L Q Q+ EQ Q+ +E ++E +E Q++ E +++ E +EL E E+++ E
Sbjct: 757 QEQELEEQEQELEEQ----EQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEE 812
Query: 246 YDQKHKE 252
+Q+ +E
Sbjct: 813 QEQELEE 819
>gi|11421723 centrosomal protein 2 [Homo sapiens] >gi|7671665|emb|CAB89415.1|
(AL121586) dJ477O4.6 (centrosomal NEK2-associated protein
1 (C-NAP1) or CEP250 centrosome associated protein) [Homo
sapiens]
Length = 2442
Score = 71.8 bits (173), Expect = 9e-12
Identities = 60/265 (22%), Positives = 129/265 (48%), Gaps = 23/265 (8%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLRE---- 57
QV+ E + + E ++H E ++++ +L + Q+E + W K++ E+ L E
Sbjct: 1265 QVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMAS 1324
Query: 58 ---KAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTK-------RDEFRQL 107
+ R + +R E + L+ ++ + A+++ L +E R + ++ R
Sbjct: 1325 LQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTA 1384
Query: 108 R-RLKMPKEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATEL-EIIQQIERYNNK 165
R LK+ E++E E+ + LQ + + K + + + +L L E +++E +
Sbjct: 1385 RSALKLKNEEVESERERAQ-ALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQ 1443
Query: 166 LQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKE----ADEYHQK 221
+QE+ K+ + K A +S+++++ NQ ++ I+ +K V + E QK
Sbjct: 1444 IQELEKQREMQKAALELLSLDLKK-RNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQK 1502
Query: 222 VVELREKIREVRRELREIERKILEY 246
+ RE+IRE+ ++ RE +R +LE+
Sbjct: 1503 LTVQREQIRELEKD-RETQRNVLEH 1526
>gi|11498637 purine NTPase, putative [Archaeoglobus fulgidus]
>gi|7451889|pir||H69378 purine NTPase homolog -
Archaeoglobus fulgidus >gi|2649562|gb|AAB90211.1|
(AE001032) purine NTPase, putative [Archaeoglobus
fulgidus]
Length = 886
Score = 71.8 bits (173), Expect = 9e-12
Identities = 76/305 (24%), Positives = 144/305 (46%), Gaps = 49/305 (16%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNL---EVKRLREKAREFKA 64
EEIK I+ E+L E RN+E +L+EL++ + R +++ EV+ L EK RE +
Sbjct: 201 EEIKSIESLREKLSEEVRNLESRLKELEEHKSRLESLRKQESSVLQEVRGLEEKLRELEK 260
Query: 65 KRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKL 124
+ E+ +RI++L+K E+ E + K + + L +L + +EK
Sbjct: 261 QLKEVVERIEDLEKKAKEVK-----------ELKPKAERYSILEKLLSEINQALRDVEKR 309
Query: 125 EWEL-QTTPNISPEREK---------QIVDQIQVLATELEIIQQIERYNNKLQEVRKKID 174
E +L + I + +K +I +I+ L ELE + E+ + L+ ++ K+D
Sbjct: 310 EGDLTREAAGIQAQLKKAEEDNSKLEEITKRIEELERELE---RFEKSHRLLETLKPKMD 366
Query: 175 QLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELRE------- 227
++ + I ++++ N + E+M KA E +KE E +K++ +
Sbjct: 367 RM----QGIKAKLEE-KNLTPDKVEKMYDLLSKAKEEEKEITEKLKKLIAKKSSLKTRGA 421
Query: 228 KIREVRRELREIERKI----LEYDQKHKELI------AYKLVARMRAKRDVNFEKAVQAL 277
++++ EL+ ER E D++H++ I K +A AK D +K + L
Sbjct: 422 QLKKAVEELKSAERTCPVCGRELDEEHRKNIMAEYTREMKRIAEELAKADEIEKKLKERL 481
Query: 278 EKFKR 282
EK ++
Sbjct: 482 EKVEK 486
>gi|6005729 centrosomal protein 2; centrosome associated protein [Homo sapiens]
>gi|2984657|gb|AAC07988.1| (AF049105) centrosomal
Nek2-associated protein 1 [Homo sapiens]
Length = 2442
Score = 71.8 bits (173), Expect = 9e-12
Identities = 60/265 (22%), Positives = 129/265 (48%), Gaps = 23/265 (8%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLRE---- 57
QV+ E + + E ++H E ++++ +L + Q+E + W K++ E+ L E
Sbjct: 1265 QVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMAS 1324
Query: 58 ---KAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTK-------RDEFRQL 107
+ R + +R E + L+ ++ + A+++ L +E R + ++ R
Sbjct: 1325 LQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTA 1384
Query: 108 R-RLKMPKEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATEL-EIIQQIERYNNK 165
R LK+ E++E E+ + LQ + + K + + + +L L E +++E +
Sbjct: 1385 RSALKLKNEEVESERERAQ-ALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQ 1443
Query: 166 LQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKE----ADEYHQK 221
+QE+ K+ + K A +S+++++ NQ ++ I+ +K V + E QK
Sbjct: 1444 IQELEKQREMQKAALELLSLDLKK-RNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQK 1502
Query: 222 VVELREKIREVRRELREIERKILEY 246
+ RE+IRE+ ++ RE +R +LE+
Sbjct: 1503 LTVQREQIRELEKD-RETQRNVLEH 1526
>pir||A45592 liver stage antigen LSA-1 - malaria parasite (Plasmodium falciparum)
>gi|9916|emb|CAA39663.1| (X56203) liver stage antigen
[Plasmodium falciparum]
Length = 1909
Score = 71.4 bits (172), Expect = 1e-11
Identities = 63/292 (21%), Positives = 141/292 (47%), Gaps = 15/292 (5%)
Query: 6 DPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKR--DEKNLEVKRLREKAREFK 63
D E+ +R K +L+E ++ L E+LQ++ + Q+R EK E + E+ R K
Sbjct: 1337 DLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQDRLAK 1396
Query: 64 AKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEK 123
K E + +++ ++ ++++ + L QE +++ L + + KEK++E+
Sbjct: 1397 EKLQEQQRDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSD 1456
Query: 124 LEWELQTTPNISP-----EREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKK 178
LE E + + E+E+ +++Q +LE Q R KLQE + ++Q ++
Sbjct: 1457 LEQERRAKEKLQEQQSDLEQERLAKEKLQEQQRDLE---QERRAKEKLQEQQSDLEQERR 1513
Query: 179 ARRAIS-----MEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVR 233
A+ + +E ++LAN+ Q ++ ++ ++A E +E ++ +EK++E +
Sbjct: 1514 AKEKLQEQQSDLEQERLANEKLQEQQRDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQ 1573
Query: 234 RELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEK 285
+L + R + ++ +L +L ++ + E+ A EK + ++
Sbjct: 1574 SDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQRDLEQERLAKEKLQEQQR 1625
Score = 70.6 bits (170), Expect = 2e-11
Identities = 62/276 (22%), Positives = 137/276 (49%), Gaps = 25/276 (9%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKARE 61
Q ++ E+++ +R+LE+ K ++ + +L++E ++ EK E + E+ R
Sbjct: 1391 QDRLAKEKLQEQQRDLEQERRAKEKLQEQQSDLEQE-----RRAKEKLQEQQSDLEQERR 1445
Query: 62 FKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERI 121
K K E +++ ++ ++++ + L QE L +++ R L + + KEK++E+
Sbjct: 1446 AKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQRDLEQERRAKEKLQEQQ 1505
Query: 122 EKLEWELQTTPNISP-----EREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQL 176
LE E + + E+E+ +++Q +LE Q R KLQE + ++Q
Sbjct: 1506 SDLEQERRAKEKLQEQQSDLEQERLANEKLQEQQRDLE---QERRAKEKLQEQQSDLEQE 1562
Query: 177 KKARRAI---SMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVE----LREKI 229
++A+ + +++Q ++ EQ Q + + KE + Q+ +E +EK+
Sbjct: 1563 RRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQ--ERLAKEKLQEQQRDLEQERLAKEKL 1620
Query: 230 REVRRELREIE---RKILEYDQKHKELIAYKLVARM 262
+E +R+L + + +K LE ++H +++A L R+
Sbjct: 1621 QEQQRDLEQRKADTKKNLERKKEHGDVLAEDLYGRL 1656
>pir||A64505 P115 homolog - Methanococcus jannaschii
Length = 1169
Score = 71.4 bits (172), Expect = 1e-11
Identities = 74/319 (23%), Positives = 152/319 (47%), Gaps = 43/319 (13%)
Query: 1 MQVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAR 60
++V VD ++ +I E+ + +E R I+ ++E L K V++ K +E++ E +
Sbjct: 669 IKVDVDLSKLNKIADEIIAIESELRKIKEEIERLSKI----VKRSSAKKMEIENTLEIIK 724
Query: 61 EFKAKRDEINQR----IKELK-KNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKE 115
+ + ++ EI ++ IKEL+ KN+D + +E E KR+E L R+ +
Sbjct: 725 KNEMRKREIAEKNTIKIKELELKNKD--------ILEELEELNLKREEI--LNRINEIES 774
Query: 116 KIEERIEKLEW------ELQTTPNISPEREKQIVDQIQVLATE-----------LEIIQQ 158
KI E IE+ E E ++ N+ +R +I ++++L E L ++++
Sbjct: 775 KINELIERREKIINELKEYESDENL--KRMNEIEGELKILEKEKAKLKNEIDKGLTLVKE 832
Query: 159 IERYNNKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEY 218
I K++E+ KK+ +L + + I ++ + + ++ +E+ K E
Sbjct: 833 I--LIPKIEELNKKVSELINKKVILEKNISFYKESIEKNLSILEEKRKRYEELAKNLKEL 890
Query: 219 HQKVVELREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALE 278
+K +L ++I + RE REI RK+ + + + EL+ K + + + E+ + E
Sbjct: 891 TEKKEQLEKEIETLERERREILRKVRDIENRINELMVEKAKYESKLEEE---ERKLYLCE 947
Query: 279 KFKRGEKLTYDEILLLQRY 297
K ++L +I L+ Y
Sbjct: 948 KVDVSKELEKKDIEELEIY 966
Score = 70.2 bits (169), Expect = 3e-11
Identities = 75/318 (23%), Positives = 150/318 (46%), Gaps = 42/318 (13%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNI----WVQKRD--EKN--------LEVKR 54
E+++IK E+E L + K E++ L I ++KR+ EKN L+ K
Sbjct: 691 ELRKIKEEIERLSKIVKRSSAKKMEIENTLEIIKKNEMRKREIAEKNTIKIKELELKNKD 750
Query: 55 LREKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR------QLR 108
+ E+ E KR+EI RI E++ +E+ + + + E EY + + R +L+
Sbjct: 751 ILEELEELNLKREEILNRINEIESKINELIERREKIINELKEYESDENLKRMNEIEGELK 810
Query: 109 RLKMPKEKIEERIEK---LEWELQTTPNISPEREK--QIVDQIQVLATELEIIQQ-IERY 162
L+ K K++ I+K L E+ P I +K +++++ +L + ++ IE+
Sbjct: 811 ILEKEKAKLKNEIDKGLTLVKEI-LIPKIEELNKKVSELINKKVILEKNISFYKESIEKN 869
Query: 163 NNKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKV 222
+ L+E RK+ ++L K + ++ + +QL + + + + +K +++ +E +
Sbjct: 870 LSILEEKRKRYEELAKNLKELTEKKEQLEKEIETLERERREILRKVRDIENRINELMVEK 929
Query: 223 VELREKIREVRREL---------REIERKILE----YDQKHKELIAYKLVARMRAKRDVN 269
+ K+ E R+L +E+E+K +E Y + + I MRA D N
Sbjct: 930 AKYESKLEEEERKLYLCEKVDVSKELEKKDIEELEIYIGELENEIKSLEPVNMRAIEDYN 989
Query: 270 F--EKAVQALEKFKRGEK 285
+ E+ + +EK K E+
Sbjct: 990 YVAERYKELIEKRKEYER 1007
>gb|AAB99663.1| (U67604) chromosome segretation protein (smc1) [Methanococcus
jannaschii]
Length = 1169
Score = 71.4 bits (172), Expect = 1e-11
Identities = 74/319 (23%), Positives = 152/319 (47%), Gaps = 43/319 (13%)
Query: 1 MQVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAR 60
++V VD ++ +I E+ + +E R I+ ++E L K V++ K +E++ E +
Sbjct: 669 IKVDVDLSKLNKIADEIIAIESELRKIKEEIERLSKI----VKRSSAKKMEIENTLEIIK 724
Query: 61 EFKAKRDEINQR----IKELK-KNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKE 115
+ + ++ EI ++ IKEL+ KN+D + +E E KR+E L R+ +
Sbjct: 725 KNEMRKREIAEKNTIKIKELELKNKD--------ILEELEELNLKREEI--LNRINEIES 774
Query: 116 KIEERIEKLEW------ELQTTPNISPEREKQIVDQIQVLATE-----------LEIIQQ 158
KI E IE+ E E ++ N+ +R +I ++++L E L ++++
Sbjct: 775 KINELIERREKIINELKEYESDENL--KRMNEIEGELKILEKEKAKLKNEIDKGLTLVKE 832
Query: 159 IERYNNKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEY 218
I K++E+ KK+ +L + + I ++ + + ++ +E+ K E
Sbjct: 833 I--LIPKIEELNKKVSELINKKVILEKNISFYKESIEKNLSILEEKRKRYEELAKNLKEL 890
Query: 219 HQKVVELREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALE 278
+K +L ++I + RE REI RK+ + + + EL+ K + + + E+ + E
Sbjct: 891 TEKKEQLEKEIETLERERREILRKVRDIENRINELMVEKAKYESKLEEE---ERKLYLCE 947
Query: 279 KFKRGEKLTYDEILLLQRY 297
K ++L +I L+ Y
Sbjct: 948 KVDVSKELEKKDIEELEIY 966
Score = 70.2 bits (169), Expect = 3e-11
Identities = 75/318 (23%), Positives = 150/318 (46%), Gaps = 42/318 (13%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNI----WVQKRD--EKN--------LEVKR 54
E+++IK E+E L + K E++ L I ++KR+ EKN L+ K
Sbjct: 691 ELRKIKEEIERLSKIVKRSSAKKMEIENTLEIIKKNEMRKREIAEKNTIKIKELELKNKD 750
Query: 55 LREKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR------QLR 108
+ E+ E KR+EI RI E++ +E+ + + + E EY + + R +L+
Sbjct: 751 ILEELEELNLKREEILNRINEIESKINELIERREKIINELKEYESDENLKRMNEIEGELK 810
Query: 109 RLKMPKEKIEERIEK---LEWELQTTPNISPEREK--QIVDQIQVLATELEIIQQ-IERY 162
L+ K K++ I+K L E+ P I +K +++++ +L + ++ IE+
Sbjct: 811 ILEKEKAKLKNEIDKGLTLVKEI-LIPKIEELNKKVSELINKKVILEKNISFYKESIEKN 869
Query: 163 NNKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKV 222
+ L+E RK+ ++L K + ++ + +QL + + + + +K +++ +E +
Sbjct: 870 LSILEEKRKRYEELAKNLKELTEKKEQLEKEIETLERERREILRKVRDIENRINELMVEK 929
Query: 223 VELREKIREVRREL---------REIERKILE----YDQKHKELIAYKLVARMRAKRDVN 269
+ K+ E R+L +E+E+K +E Y + + I MRA D N
Sbjct: 930 AKYESKLEEEERKLYLCEKVDVSKELEKKDIEELEIYIGELENEIKSLEPVNMRAIEDYN 989
Query: 270 F--EKAVQALEKFKRGEK 285
+ E+ + +EK K E+
Sbjct: 990 YVAERYKELIEKRKEYER 1007
>pir||A72287 hypothetical protein TM1182 - Thermotoga maritima (strain MSB8)
>gi|4981731|gb|AAD36257.1|AE001774_14 (AE001774)
chromosome segregation SMC protein, putative [Thermotoga
maritima]
Length = 1170
Score = 71.4 bits (172), Expect = 1e-11
Identities = 61/287 (21%), Positives = 144/287 (49%), Gaps = 26/287 (9%)
Query: 10 IKRIKRELEELHNEKRNIELKLEELQKEL----NIWVQKRDE---KNLEVKRLREKAREF 62
+KR +++LE E++ K++ +QKEL W R E + E++R + ++
Sbjct: 227 LKRERKKLEFYQEEEKKTNEKIKNIQKELVELETKWSTLRSEFGEMDQEIERYTKLLEDY 286
Query: 63 KAKRDEI-------NQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKM-PK 114
K +++++ + ++ + + E++ +LD L + EY+ + +E + + M
Sbjct: 287 KKRQNDLVEMKGFYSSKLADSENKYVELSTRLDELEKRREEYKKRLEEMEYIFKGVMGDY 346
Query: 115 EKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKID 174
E+ + +EK E E + + ++EK+ + +++ ++LE +QI + N+L + + ++
Sbjct: 347 ERKAKELEKFEKEKENLLSRFNDKEKEFL-RVRDEISKLE--KQILKLENELLRIGETLE 403
Query: 175 QLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRR 234
L+K R+ +I + + + + ++ +E+ +E + +++ +RE++ E+
Sbjct: 404 DLEKRRKITENQILTRRRELEDKKNEFKEISRRVEELDEEEKKLTEELNAVRERLEEIEG 463
Query: 235 ELREIERKILEYDQKHKELIAYKLVARMRAKRDV----NFEKAVQAL 277
E+R + LE D K K L + M +RD+ F +AV+A+
Sbjct: 464 EIRRVN---LEIDAKEKRLREIQFEKEM-IERDMREYRGFSRAVRAV 506
Score = 70.2 bits (169), Expect = 3e-11
Identities = 81/346 (23%), Positives = 157/346 (44%), Gaps = 63/346 (18%)
Query: 3 VKVDPEEIKR----IKRELEELHNEKRNIELKLEELQKELNIWVQKRDE-KNLEVKRLRE 57
+K + E +K ++REL EL + + + L E+ + +N Q ++E +NLE +
Sbjct: 695 LKTEQENLKNQEALVQRELFELSRKSSSTKTVLSEILRSIN---QLQEEVENLEKLLVEY 751
Query: 58 KARE--FKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTK-RDEFRQ-LRRLKMP 113
+A+E A+R++I + I ELK+NR+ + L Y E LE K DE + + L+
Sbjct: 752 RAKEEGLNARREKIFEEIDELKQNRENLQRSLTE-YSEELEKEKKILDELNEKIFTLRAE 810
Query: 114 KEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKI 173
+ E ++ E E++ T + ER + + I++ T LE +++E Y ++E ++I
Sbjct: 811 VGNLLETKDRYEKEMRDTGKMI-ERIARETEDIKLQMTSLE--EEMENYRKFIREHEREI 867
Query: 174 DQLKKARRAI--------------SMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYH 219
+ LKK ++ E+Q++ N+ + E+ + ++ E
Sbjct: 868 EHLKKEMDSVFEAMKLHRSGKEEKMRELQEVENRMDELKEEKERLRNHLHQIDLALQETR 927
Query: 220 QKVVEL---------------REKIREVRRELREIERKIL-----------EYDQKHKEL 253
K+ L EK+ E+ R+++++E KI EY++ +E
Sbjct: 928 LKIANLLEEFSGNEEDVEELDEEKLEEIYRQIKDLENKIKYLGPVDLTAIDEYEKLREE- 986
Query: 254 IAYKLVARMRAKRDVNFEKAVQALEKFKR-GEKLTYDEILLLQRYN 298
Y+ + + + + K + +EK R E L +D + QR N
Sbjct: 987 --YEEILKQKEDLEEAKRKLEEIIEKTDREAESLLFD---VYQRVN 1027
>dbj|BAA92557.1| (AB037740) KIAA1319 protein [Homo sapiens]
Length = 1208
Score = 71.4 bits (172), Expect = 1e-11
Identities = 60/291 (20%), Positives = 130/291 (44%), Gaps = 39/291 (13%)
Query: 2 QVKVDPEEIKR-----------IKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNL 50
Q + D E+++R ++ E +++ R ++ +LEE +E W Q +KN
Sbjct: 526 QYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHW-QSMFQKNK 584
Query: 51 EVKRLREKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRL 110
E + +A + E+ Q E ++ +E+ K+++L +E + R + RQ+ L
Sbjct: 585 E---------DLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVL 635
Query: 111 KMPKEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYN----NKL 166
K + +E +++L+ E Q+ R++++ Q+ VL E + +++E N L
Sbjct: 636 KKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTL 695
Query: 167 QEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVE-- 224
Q++R+ ++ KA+ E L + + +T ++ DE ++ Q++ E
Sbjct: 696 QQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETR 755
Query: 225 ------------LREKIREVRRELREIERKILEYDQKHKELIAYKLVARMR 263
LR+K++ + E +++E + ++ L A K R
Sbjct: 756 GLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEAR 806
>gb|AAF74498.1|AF263462_1 (AF263462) cingulin [Homo sapiens]
Length = 1203
Score = 71.4 bits (172), Expect = 1e-11
Identities = 60/291 (20%), Positives = 130/291 (44%), Gaps = 39/291 (13%)
Query: 2 QVKVDPEEIKR-----------IKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNL 50
Q + D E+++R ++ E +++ R ++ +LEE +E W Q +KN
Sbjct: 521 QYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHW-QSMFQKNK 579
Query: 51 EVKRLREKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRL 110
E + +A + E+ Q E ++ +E+ K+++L +E + R + RQ+ L
Sbjct: 580 E---------DLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVL 630
Query: 111 KMPKEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYN----NKL 166
K + +E +++L+ E Q+ R++++ Q+ VL E + +++E N L
Sbjct: 631 KKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTL 690
Query: 167 QEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVE-- 224
Q++R+ ++ KA+ E L + + +T ++ DE ++ Q++ E
Sbjct: 691 QQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETR 750
Query: 225 ------------LREKIREVRRELREIERKILEYDQKHKELIAYKLVARMR 263
LR+K++ + E +++E + ++ L A K R
Sbjct: 751 GLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEAR 801
>gb|AAG27458.1|AF305694_1 (AF305694) latent nuclear antigen [Kaposi's sarcoma-associated
herpesvirus]
Length = 1036
Score = 71.4 bits (172), Expect = 1e-11
Identities = 56/287 (19%), Positives = 149/287 (51%), Gaps = 16/287 (5%)
Query: 6 DPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAK 65
+P++ + ++E ++ +++ + + E+ Q E Q++DE+ + ++ +++ ++ + +
Sbjct: 509 EPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQQDEQQQDEQQQDEQQ 568
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
+DE Q+ ++ +DE Q+ + + +++E Q + E+ E+ +E+ E
Sbjct: 569 QDEQEQQDEQ---QQDE---------QQQQDEQEQQEEQEQQEEQEQELEEQEQELEEQE 616
Query: 126 WELQTTPNISPEREKQIVDQIQVLAT-ELEIIQQIERYNNKLQEVRKKIDQLKKARRAIS 184
EL+ E+E+++ +Q Q L E E+ +Q + + QE+ ++ +L++ + +
Sbjct: 617 QELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELDEQEQELEEQEQELE 676
Query: 185 MEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKIL 244
+ Q+L Q Q+ EQ + ++ E++++ E ++ EL E+ +E+ + +E E + +
Sbjct: 677 EQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEV 736
Query: 245 EYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEI 291
E ++ +E + V +++ E+ Q LE+ + E+ +E+
Sbjct: 737 EEQEQEQEEQELEEVEEQEQEQE---EQEEQELEEVEEQEEQELEEV 780
Score = 69.5 bits (167), Expect = 4e-11
Identities = 50/239 (20%), Positives = 124/239 (50%), Gaps = 5/239 (2%)
Query: 15 RELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIK 74
++ E E + E E Q+E ++ E + + +++ ++ + ++DE Q +
Sbjct: 492 QQQEPQQQEPQQQEPLQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQ 551
Query: 75 ELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWELQTTPNI 134
+ + + + + D Q+ E + ++ + Q ++ + +++ +E+ E+ E EL+
Sbjct: 552 QQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQELEEQEQE 611
Query: 135 SPEREKQIVDQIQVLAT-ELEIIQQIERYNNKLQEVRKKIDQLKKARRAISMEIQQLANQ 193
E+E+++ +Q Q L E E+ +Q + + QE+ ++ +L++ + + + Q+L Q
Sbjct: 612 LEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELDEQEQELEEQ 671
Query: 194 SQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILEYDQKHKE 252
Q+ EQ Q+ +E ++E +E Q++ E +++ E +EL E E+++ E +Q+ +E
Sbjct: 672 EQELEEQ----EQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEE 726
Score = 68.7 bits (165), Expect = 8e-11
Identities = 53/227 (23%), Positives = 118/227 (51%), Gaps = 19/227 (8%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKARE 61
Q + +E++ ++ELEE E E +LEE ++EL Q+ +E+ E++ ++ E
Sbjct: 597 QQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEE 656
Query: 62 FKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERI 121
+ + DE Q ++E ++ +E +L+ QE E + +E Q + L+ ++++EE+
Sbjct: 657 QEQELDEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEE--QEQELEEQEQELEEQE 714
Query: 122 EKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARR 181
++LE E+E+++ +Q Q E Q+ E+ +L+EV ++ + ++
Sbjct: 715 QELE-----------EQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEE--- 760
Query: 182 AISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREK 228
E Q+L +Q +++ + ++ ++ +E +E Q+ VE +E+
Sbjct: 761 ---QEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQ 804
Score = 68.7 bits (165), Expect = 8e-11
Identities = 58/261 (22%), Positives = 130/261 (49%), Gaps = 23/261 (8%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
E+ ++ ++E +E ++ E +LEE ++EL Q+ +E+ E++ ++ E + + +
Sbjct: 582 EQQQQDEQEQQEEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELE 641
Query: 68 EINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWE 127
E Q ++E ++ +E +LD QE E + +E Q E+ E+ +E+ E E
Sbjct: 642 EQEQELEEQEQELEEQEQELDEQEQELEEQEQELEEQEQ------ELEEQEQELEEQEQE 695
Query: 128 LQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAISMEI 187
L+ E+E+++ +Q Q L + + +++ E+ +L+EV ++ + E
Sbjct: 696 LEEQEQELEEQEQELEEQEQELEEQEQELEEQEQ-EQELEEVEEQEQE---------QEE 745
Query: 188 QQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILE-Y 246
Q+L +Q EQ + Q+ +EV+++ ++ EL E + +EL E+E + +
Sbjct: 746 QELEEVEEQEQEQEEQEEQELEEVEEQEEQ------ELEEVEEQEEQELEEVEEQEQQGV 799
Query: 247 DQKHKELIAYKLVARMRAKRD 267
+Q+ +E + ++ + D
Sbjct: 800 EQQEQETVEEPIILHGSSSED 820
>sp|P54697|MYSJ_DICDI MYOSIN IJ HEAVY CHAIN >gi|7489890|pir||T18278 myosin heavy chain
[similarity] - slime mold (Dictyostelium discoideum)
>gi|1150766|gb|AAA85186.1| (U42409) myosin heavy chain
[Dictyostelium discoideum]
Length = 2245
Score = 71.0 bits (171), Expect = 1e-11
Identities = 58/264 (21%), Positives = 138/264 (51%), Gaps = 26/264 (9%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKN----LEVKRLR------- 56
+++++ K++ EEL ++ +L+ ++E + Q+RD N LE+++L+
Sbjct: 1097 QQLQQFKQQSEELSSKLSKTTQQLDFNKQEFDRLSQERDTDNTNNQLEIQQLKKANSTLE 1156
Query: 57 EKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRD-EFRQLRRLKMPKE 115
E RD + +++ EL+ I +LD L Q++ ++++ E +QL +L
Sbjct: 1157 EDYFSLSGIRDNLERQVLELRDENQLIKERLDSLGQQSSQFQSGAALEKQQLEQL----- 1211
Query: 116 KIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATE----LEI-IQQIERYNNKLQEVR 170
++E+ E+L +L + S E K+ ++Q+++ T+ L+I +Q E+ N K+++++
Sbjct: 1212 -VQEQSEQL-IKLSSEKLGSEEEAKKQINQLELELTDHKSKLQIQLQLTEQSNEKIKKLK 1269
Query: 171 KKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIR 230
K+++ + ++ + E++++ Q ++ + VK E+ + V +EKI
Sbjct: 1270 GKLEEYQDEKKQLQQELERIKQSKQSVEDEKNSLITQLTTVKFESTQVSTNVSHQKEKIT 1329
Query: 231 EVRRELREIERKI--LEYDQKHKE 252
++ + E+ + I L+ +QK+K+
Sbjct: 1330 TLKSTIEELNKSIGKLQAEQKNKD 1353
>prf||2012303A SP-H antigen [Homo sapiens]
Length = 2115
Score = 70.6 bits (170), Expect = 2e-11
Identities = 70/312 (22%), Positives = 154/312 (48%), Gaps = 40/312 (12%)
Query: 15 RELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIK 74
++LE L EK KLE LQ++L + + RD V + + + E K +E+ ++
Sbjct: 604 KQLEALEKEKA---AKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE 660
Query: 75 ELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWELQTTPNI 134
++ + E A++ L L+ R+++ + + R+ K++++E+++ L+ L+ T
Sbjct: 661 TARQEQHEAQAQVAEL---ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGS 717
Query: 135 SPEREKQIVDQI--------QVLATELEIIQQIERYNNKLQEVR-------KKIDQLKKA 179
E +++ D + ++ A +++Q +R +L+E R ++ QL +A
Sbjct: 718 LEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEA 777
Query: 180 RRAISMEI-QQLANQSQQFH------EQMIKTY----QKADEVKKEADEY----HQKVVE 224
+A + + ++LA H EQ++K ++ ++ ++E +Y ++++
Sbjct: 778 HQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMT 837
Query: 225 LREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQAL-EKFKRG 283
L+E+ + R+EL+E + K+ + H EL + + A+ N +A+Q + EK R
Sbjct: 838 LKEECEKARQELQEAKEKVAGI-ESHSELQISRQQNEL-AELHANLARALQQVQEKEVRA 895
Query: 284 EKLTYDEILLLQ 295
+KL D++ LQ
Sbjct: 896 QKLA-DDLSTLQ 906
>pir||T08621 centrosome associated protein CEP250 - human
>gi|2832237|gb|AAC06349.1| (AF022655) cep250 centrosome
associated protein [Homo sapiens]
Length = 2442
Score = 70.6 bits (170), Expect = 2e-11
Identities = 60/265 (22%), Positives = 128/265 (47%), Gaps = 23/265 (8%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLRE---- 57
QV+ E + + E ++H E ++++ +L + Q+E + W K++ E+ L E
Sbjct: 1265 QVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMAS 1324
Query: 58 ---KAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTK-------RDEFRQL 107
+ R + +R E + L+ ++ + A+++ L +E R + ++ R
Sbjct: 1325 LQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTA 1384
Query: 108 R-RLKMPKEKIEERIEKLEWELQTTPNISPEREKQIVDQIQVLATEL-EIIQQIERYNNK 165
R LK+ E++E E+ + LQ + + K + + + +L L E +++E +
Sbjct: 1385 RSALKLKNEEVESERERAQ-ALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQ 1443
Query: 166 LQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKE----ADEYHQK 221
+QE+ K+ + K A +S+++++ NQ ++ I+ +K V + E QK
Sbjct: 1444 IQELEKQREMQKAALELLSLDLKK-RNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQK 1502
Query: 222 VVELREKIREVRRELREIERKILEY 246
+ RE+IRE ++ RE +R +LE+
Sbjct: 1503 LTVQREQIREPEKD-RETQRNVLEH 1526
>gb|AAD19746.1| (AF132478) Ese1 protein [Mus musculus]
Length = 1213
Score = 70.6 bits (170), Expect = 2e-11
Identities = 65/309 (21%), Positives = 149/309 (48%), Gaps = 44/309 (14%)
Query: 4 KVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFK 63
+++ E +R +RE +E KR +EL+ ++L+K+ + Q+ +E+ E++R RE +
Sbjct: 384 QLERAEQERKERERQE-QEAKRQLELE-KQLEKQRELERQREEERRKEIERREAAKRELE 441
Query: 64 AKR----------DEINQRIKE------LKKNRDEINAKLDLLYQEALEYRTKRDEFRQL 107
+R + +NQR KE LK R + +L+ L + + K + R
Sbjct: 442 RQRQLEWERNRRQELLNQRNKEQEGTVVLKARRKTLEFELEALNDKKHQLEGKLQDIR-- 499
Query: 108 RRLKMPKEKIEERIEKLEWELQTTPNISPEREK------QIVDQIQVLATELEIIQQIER 161
RL +++IE + E + ++ + ++ +++ + Q+L+ +L+ +QQ
Sbjct: 500 CRLATQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILSDQLKQVQQNSL 559
Query: 162 YNNKL--------------QEVRKKIDQLKKARRAISMEIQQLANQSQQFHE----QMIK 203
+ + L Q++R+++D++++ R+ EI NQ ++ E Q ++
Sbjct: 560 HRDSLLTLKRALEAKELARQQLREQLDEVERETRSKLQEIDVFNNQLKELREIHSKQQLQ 619
Query: 204 TYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILEYDQKHKELIAYKLVARMR 263
+ + + + E +K +EL ++ + +R ++E +++ LE+ Q+ ++ K R
Sbjct: 620 KQRSLEAARLKQKEQERKSLELEKQKEDAQRRVQERDKQWLEHVQQEEQPRPRKPHEEDR 679
Query: 264 AKRDVNFEK 272
KR+ + K
Sbjct: 680 LKREDSVRK 688
>gi|6754392 intersectin (SH3 domain protein 1A); intersection (SH3 domain
protein 1A); Eh domain, SH3 domain regulator of
endocytosis 1 [Mus musculus] >gi|4378891|gb|AAD19749.1|
(AF132481) Ese1L protein [Mus musculus]
Length = 1714
Score = 70.6 bits (170), Expect = 2e-11
Identities = 65/309 (21%), Positives = 149/309 (48%), Gaps = 44/309 (14%)
Query: 4 KVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFK 63
+++ E +R +RE +E KR +EL+ ++L+K+ + Q+ +E+ E++R RE +
Sbjct: 384 QLERAEQERKERERQE-QEAKRQLELE-KQLEKQRELERQREEERRKEIERREAAKRELE 441
Query: 64 AKR----------DEINQRIKE------LKKNRDEINAKLDLLYQEALEYRTKRDEFRQL 107
+R + +NQR KE LK R + +L+ L + + K + R
Sbjct: 442 RQRQLEWERNRRQELLNQRNKEQEGTVVLKARRKTLEFELEALNDKKHQLEGKLQDIR-- 499
Query: 108 RRLKMPKEKIEERIEKLEWELQTTPNISPEREK------QIVDQIQVLATELEIIQQIER 161
RL +++IE + E + ++ + ++ +++ + Q+L+ +L+ +QQ
Sbjct: 500 CRLATQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILSDQLKQVQQNSL 559
Query: 162 YNNKL--------------QEVRKKIDQLKKARRAISMEIQQLANQSQQFHE----QMIK 203
+ + L Q++R+++D++++ R+ EI NQ ++ E Q ++
Sbjct: 560 HRDSLLTLKRALEAKELARQQLREQLDEVERETRSKLQEIDVFNNQLKELREIHSKQQLQ 619
Query: 204 TYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILEYDQKHKELIAYKLVARMR 263
+ + + + E +K +EL ++ + +R ++E +++ LE+ Q+ ++ K R
Sbjct: 620 KQRSLEAARLKQKEQERKSLELEKQKEDAQRRVQERDKQWLEHVQQEEQPRPRKPHEEDR 679
Query: 264 AKRDVNFEK 272
KR+ + K
Sbjct: 680 LKREDSVRK 688
>pir||S23647 NuMA protein - human >gi|35119|emb|CAA77669.1| (Z11583) NuMA
protein [Homo sapiens]
Length = 2115
Score = 70.6 bits (170), Expect = 2e-11
Identities = 70/312 (22%), Positives = 154/312 (48%), Gaps = 40/312 (12%)
Query: 15 RELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIK 74
++LE L EK KLE LQ++L + + RD V + + + E K +E+ ++
Sbjct: 604 KQLEALEKEKA---AKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE 660
Query: 75 ELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWELQTTPNI 134
++ + E A++ L L+ R+++ + + R+ K++++E+++ L+ L+ T
Sbjct: 661 TARQEQHEAQAQVAEL---ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGS 717
Query: 135 SPEREKQIVDQI--------QVLATELEIIQQIERYNNKLQEVR-------KKIDQLKKA 179
E +++ D + ++ A +++Q +R +L+E R ++ QL +A
Sbjct: 718 LEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEA 777
Query: 180 RRAISMEI-QQLANQSQQFH------EQMIKTY----QKADEVKKEADEY----HQKVVE 224
+A + + ++LA H EQ++K ++ ++ ++E +Y ++++
Sbjct: 778 HQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMT 837
Query: 225 LREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQAL-EKFKRG 283
L+E+ + R+EL+E + K+ + H EL + + A+ N +A+Q + EK R
Sbjct: 838 LKEECEKARQELQEAKEKVAGI-ESHSELQISRQQNEL-AELHANLARALQQVQEKEVRA 895
Query: 284 EKLTYDEILLLQ 295
+KL D++ LQ
Sbjct: 896 QKLA-DDLSTLQ 906
>gi|11432935 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 1624
Score = 70.6 bits (170), Expect = 2e-11
Identities = 70/312 (22%), Positives = 154/312 (48%), Gaps = 40/312 (12%)
Query: 15 RELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIK 74
++LE L EK KLE LQ++L + + RD V + + + E K +E+ ++
Sbjct: 592 KQLEALEKEKA---AKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE 648
Query: 75 ELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWELQTTPNI 134
++ + E A++ L L+ R+++ + + R+ K++++E+++ L+ L+ T
Sbjct: 649 TARQEQHEAQAQVAEL---ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGS 705
Query: 135 SPEREKQIVDQI--------QVLATELEIIQQIERYNNKLQEVR-------KKIDQLKKA 179
E +++ D + ++ A +++Q +R +L+E R ++ QL +A
Sbjct: 706 LEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEA 765
Query: 180 RRAISMEI-QQLANQSQQFH------EQMIKTY----QKADEVKKEADEY----HQKVVE 224
+A + + ++LA H EQ++K ++ ++ ++E +Y ++++
Sbjct: 766 HQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMT 825
Query: 225 LREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQAL-EKFKRG 283
L+E+ + R+EL+E + K+ + H EL + + A+ N +A+Q + EK R
Sbjct: 826 LKEECEKARQELQEAKEKVAGI-ESHSELQISRQQNEL-AELHANLARALQQVQEKEVRA 883
Query: 284 EKLTYDEILLLQ 295
+KL D++ LQ
Sbjct: 884 QKLA-DDLSTLQ 894
>pir||T24635 hypothetical protein T07C4.10a - Caenorhabditis elegans
>gi|3979898|emb|CAA88136.1| (Z48055) similarity to yeast
heat shock protein H104 (Swiss Port accession number
P31359)~cDNA EST yk274a7.5 comes from this gene~cDNA EST
yk681c11.3 comes from this gene~cDNA EST yk508g10.5
comes from this gene~cDNA EST yk681c11.5 comes from this
gene> >gi|3979903|emb|CAA82580.1| (Z29443) similarity to
yeast heat shock protein H104 (Swiss Port accession
number P31359)~cDNA EST yk274a7.5 comes from this
gene~cDNA EST yk681c11.3 comes from this gene~cDNA EST
yk508g10.5 comes from this gene~cDNA EST yk681c11.5
comes from this gene>
Length = 1138
Score = 70.2 bits (169), Expect = 3e-11
Identities = 53/259 (20%), Positives = 128/259 (48%), Gaps = 13/259 (5%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQK----RDEKNLEVKRLREKAREFKA 64
E+ ++ E+E + +K ++E +L + +K + Q R + ++K +EK +++
Sbjct: 359 EVDQLHSEIEVIGKKKSDLENRLFDYEKLKAQFEQDENKLRADLEKKLKTSQEKLVKYEG 418
Query: 65 KRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR--------QLRRLKMPKEK 116
K +E+ R+ + +K +E+ A+ L ++ + + DE + Q + E+
Sbjct: 419 KIEELQSRLNKKRKELEEVQAENRKLLEDKNTHDFELDEAKVQGEHLEKQRKEAWEKVEQ 478
Query: 117 IEERIEKLEWELQTTPNISPEREKQIVDQIQVLATEL-EIIQQIERYNNKLQEVRKKIDQ 175
++E + +LE EL + + EK + D + ++ E+ +++E+ + K +E +++++
Sbjct: 479 LQEMLGELEAELDRQKELKLQLEKDMEDLRKEHEGQMAELEKRLEKVSEKEKEAIEQLEK 538
Query: 176 LKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRE 235
++K + I E L+ Q E I + DE+ + +V L EKI E +R
Sbjct: 539 IQKENKTIVKENVYLSESKQVLLESEINLKNELDEMAVKLRNSQHQVAGLNEKISEEKRR 598
Query: 236 LREIERKILEYDQKHKELI 254
++ + + D+++++L+
Sbjct: 599 RKKQDADVTRLDEQNQKLL 617
Score = 70.2 bits (169), Expect = 3e-11
Identities = 63/315 (20%), Positives = 160/315 (50%), Gaps = 31/315 (9%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKARE 61
++K E++ + + ++EEL + +LEE+Q E ++ ++ + E+ + +
Sbjct: 405 KLKTSQEKLVKYEGKIEELQSRLNKKRKELEEVQAENRKLLEDKNTHDFELDEAKVQGEH 464
Query: 62 FKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-----QLRRLKMPKEK 116
+ +R E +++++L++ E+ A+LD + L+ ++ R Q+ L+ EK
Sbjct: 465 LEKQRKEAWEKVEQLQEMLGELEAELDRQKELKLQLEKDMEDLRKEHEGQMAELEKRLEK 524
Query: 117 IEER-------IEKLEWELQT--TPNISPEREKQIVDQIQV-LATEL-EIIQQIERYNNK 165
+ E+ +EK++ E +T N+ KQ++ + ++ L EL E+ ++ ++
Sbjct: 525 VSEKEKEAIEQLEKIQKENKTIVKENVYLSESKQVLLESEINLKNELDEMAVKLRNSQHQ 584
Query: 166 LQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVEL 225
+ + +KI + K+ R+ ++ +L Q+Q ++++ Q + E+ +E + +++ L
Sbjct: 585 VAGLNEKISEEKRRRKKQDADVTRLDEQNQ----KLLREAQDSAELLEEVQKGKREIDHL 640
Query: 226 REKIREVRRE---LREIERKILEYDQKHKE-LIAYKLVARMRAKRDVNFEKAVQALEKFK 281
R+++ E + ++++K+ E +H+E L+ +L M+ +RD++ +E +
Sbjct: 641 RQQLAHQSSEAGSVGQLQQKLAE--SEHREYLLQLELERVMKMERDLD-----GRIEGYI 693
Query: 282 RGEKLTYDEILLLQR 296
R E +E+ L++
Sbjct: 694 RSEAAANNELERLRK 708
>pir||F75103 probable purine NTPase PAB0812 - Pyrococcus abyssi (strain Orsay)
>gi|5458643|emb|CAB50131.1| (AJ248286) purine NTPase,
putative [Pyrococcus abyssi]
Length = 880
Score = 69.9 bits (168), Expect = 3e-11
Identities = 70/310 (22%), Positives = 150/310 (47%), Gaps = 37/310 (11%)
Query: 1 MQVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRD----EKNLEVKRLR 56
+++K EE+KR E +L R +E+KL E +I Q ++ K ++ L
Sbjct: 463 LEIKKIEEELKRTTEEERKLRVNLRKLEIKLREFSVMRDIAEQIKELESKLKGFNLEELE 522
Query: 57 EKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEK 116
+K REF+ +E N+ EL + + DL +ALE R K E ++R+ K E
Sbjct: 523 QKEREFEGLNEEFNKLKGEL------LGLERDLKRIKALEGRRKLIE-EKVRKAKEELEN 575
Query: 117 IEERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQL 176
+ ++ +L +E N+ + ++ D+ V A + E ++ NKL++ + ++DQ
Sbjct: 576 LHRQLRELGFESVEELNLRIQELEEFHDK-YVEAKKSE--SELRELKNKLEKEKTELDQA 632
Query: 177 KKARRAISMEIQQ----LANQSQQFHEQ--------MIKTYQ-------KADEVKKEADE 217
+ + EI++ L + +F+E+ ++K + + +E+KK ++
Sbjct: 633 FEMLADVENEIEEKEAKLKDLESKFNEEEYEEKRERLVKLEREVSSLTARLEELKKSVEQ 692
Query: 218 YH---QKVVELREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAV 274
+K+ E +E+ + + E++++E+ + + + K++ YK +A+ +A ++ E A
Sbjct: 693 IKATLRKLKEEKEEREKAKLEIKKLEKALSKVEDLRKKIKDYKTLAKEQALNRIS-EIAS 751
Query: 275 QALEKFKRGE 284
+ +F G+
Sbjct: 752 EIFSEFTDGK 761
>sp|P25386|USO1_YEAST INTRACELLULAR PROTEIN TRANSPORT PROTEIN USO1 >gi|4778|emb|CAA38253.1|
(X54378) Uso1 protein [Saccharomyces cerevisiae]
Length = 1790
Score = 69.5 bits (167), Expect = 4e-11
Identities = 56/253 (22%), Positives = 117/253 (46%), Gaps = 13/253 (5%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREK----AREFKA 64
EIK I LEE+ + N+ + E + KEL + + + V +L EK A +K
Sbjct: 914 EIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKD 973
Query: 65 KRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPK--EKIEERIE 122
+ E IK ++++++E + +L L Q ++ ++ E Q+ R + K E++++ I
Sbjct: 974 MQAENESLIKAVEESKNESSIQLSNL-QNKIDSMSQEKENFQIERGSIEKNIEQLKKTIS 1032
Query: 123 KLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRA 182
LE + + S + + QI +L +LE E KI +L K R
Sbjct: 1033 DLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTAN------DENVNKISELTKTREE 1086
Query: 183 ISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERK 242
+ E+ N + ++ + + EVK+ + ++ ++L ++ E +++L +
Sbjct: 1087 LEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRAN 1146
Query: 243 ILEYDQKHKELIA 255
+ +++H++L A
Sbjct: 1147 LESLEKEHEDLAA 1159
>sp|P13538|MYSS_CHICK MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT >gi|86355|pir||JX0178
myosin heavy chain, fast skeletal muscle, adult
[validated] - chicken >gi|238274|gb|AAB20215.1| myosin
heavy chain [chickens, skeletal muscle, Peptide, 1938 aa]
Length = 1938
Score = 69.5 bits (167), Expect = 4e-11
Identities = 59/277 (21%), Positives = 135/277 (48%), Gaps = 42/277 (15%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVK-------------- 53
+E+ +K E E+ E E K +EL++++ + +Q++++ L+V+
Sbjct: 849 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCD 908
Query: 54 RLREKAREFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMP 113
+L + + +AK E+ +R ++ ++ E+ AK L E E + D+ +L K+
Sbjct: 909 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL-ELTLAKVE 967
Query: 114 KEK--IEERIEKLEWEL----QTTPNISPERE------KQIVDQIQVLATELEII----- 156
KEK E +++ L E+ +T ++ E++ +Q +D +QV ++ +
Sbjct: 968 KEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVNTLTKAKT 1027
Query: 157 ---QQIERYNNKLQEVRKKIDQLKKARRAISME-------IQQLANQSQQFHEQMIKTYQ 206
QQ++ L++ +K L++A+R + + I L N QQ E++ K
Sbjct: 1028 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDF 1087
Query: 207 KADEVKKEADEYHQKVVELREKIREVRRELREIERKI 243
+ +++ + ++ ++L++KI+E++ + E+E +I
Sbjct: 1088 EISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEI 1124
>pir||S05515 myosin heavy chain, skeletal muscle - chicken (fragment)
Length = 429
Score = 69.5 bits (167), Expect = 4e-11
Identities = 60/277 (21%), Positives = 138/277 (49%), Gaps = 42/277 (15%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
+E+ +K E E+ E E K +EL++++ + +Q++++ L+V+ + + + ++D
Sbjct: 8 KEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERQD 67
Query: 68 EI-------NQRIKELKK---NRDEINAKLDL----LYQEALEYRTKRDEFRQLRRLKMP 113
++ +IKE+ + + +EINA+L L E E + D+ +L K+
Sbjct: 68 QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL-ELTLAKVE 126
Query: 114 KEK--IEERIEKLEWEL----QTTPNISPERE------KQIVDQIQV--------LATEL 153
KEK E +++ L E+ +T ++ E++ +Q +D +QV +
Sbjct: 127 KEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVNTLTKAKT 186
Query: 154 EIIQQIERYNNKLQEVRKKIDQLKKARRAISME-------IQQLANQSQQFHEQMIKTYQ 206
++ QQ++ L++ +K L++A+R + + I L N QQ E++ K
Sbjct: 187 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDF 246
Query: 207 KADEVKKEADEYHQKVVELREKIREVRRELREIERKI 243
+ +++ + ++ ++L++KI+E++ + E+E +I
Sbjct: 247 EISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEI 283
>gb|AAA72295.1| (L04159) [Plasmodium falciparum 3' end.], gene product
Length = 503
Score = 69.5 bits (167), Expect = 4e-11
Identities = 61/255 (23%), Positives = 122/255 (46%), Gaps = 23/255 (9%)
Query: 12 RIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNL---EVKRLREKAREFKAKRDE 68
RI E L+NE LKL EL N ++ ++ L E + +E+ R KAK++E
Sbjct: 4 RIVDEATYLNNELDKFLLKLNELLSHNNNDIKDLGDEKLILKEEEERKERERLEKAKQEE 63
Query: 69 INQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWE- 127
+ + ++K + E + L +E E K +E R+ + + +++ EE +++ E E
Sbjct: 64 ERKERERIEKEKQE----KERLEREKQEQLKKEEELRKKEQERQEQQQKEEALKRQEQER 119
Query: 128 --------LQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKK- 178
Q + E+++Q+ + ++ E E +Q+ E + QE +K ++LK+
Sbjct: 120 LQKEEELKRQEQERLEREKQEQLQKEEELKRQEQERLQKEEALKRQEQERLQKEEELKRQ 179
Query: 179 ARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELRE 238
+ + E Q+ + ++ Q + QK + +K++ E QK EL+ R+E
Sbjct: 180 EQERLEREKQEQLQKEEELKRQEQERLQKEEALKRQEQERLQKEEELK------RQEQER 233
Query: 239 IERKILEYDQKHKEL 253
+ERK +E ++ + +
Sbjct: 234 LERKKIELAEREQHI 248
>gi|6320145 Integrin analogue gene; Uso1p [Saccharomyces cerevisiae]
>gi|2133190|pir||S67593 transport protein USO1 - yeast
(Saccharomyces cerevisiae) >gi|1431059|emb|CAA98621.1|
(Z74106) ORF YDL058w [Saccharomyces cerevisiae]
Length = 1790
Score = 69.5 bits (167), Expect = 4e-11
Identities = 56/253 (22%), Positives = 117/253 (46%), Gaps = 13/253 (5%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREK----AREFKA 64
EIK I LEE+ + N+ + E + KEL + + + V +L EK A +K
Sbjct: 914 EIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKD 973
Query: 65 KRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPK--EKIEERIE 122
+ E IK ++++++E + +L L Q ++ ++ E Q+ R + K E++++ I
Sbjct: 974 MQAENESLIKAVEESKNESSIQLSNL-QNKIDSMSQEKENFQIERGSIEKNIEQLKKTIS 1032
Query: 123 KLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRA 182
LE + + S + + QI +L +LE E KI +L K R
Sbjct: 1033 DLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTAN------DENVNKISELTKTREE 1086
Query: 183 ISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERK 242
+ E+ N + ++ + + EVK+ + ++ ++L ++ E +++L +
Sbjct: 1087 LEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRAN 1146
Query: 243 ILEYDQKHKELIA 255
+ +++H++L A
Sbjct: 1147 LESLEKEHEDLAA 1159
>pir||T07111 MAR binding filament-like protein 1 - tomato
>gi|1771158|emb|CAA69181.1| (Y07861) MFP1 protein
[Lycopersicon esculentum]
Length = 697
Score = 69.5 bits (167), Expect = 4e-11
Identities = 68/308 (22%), Positives = 141/308 (45%), Gaps = 23/308 (7%)
Query: 9 EIKRIKRELEELHNEKRNIELKL---EELQKELNIWVQKRDEKNLEVKRLREKAREFKAK 65
EIK +K +E+ +R +ELK + L +LN + +RDE E+ ++++ EFK+
Sbjct: 300 EIKELK---DEIQKRERELELKCVSEDNLNVQLNSLLLERDESKKELHAIQKEYSEFKSN 356
Query: 66 RDE---INQRIKELKKNRDEINAKLDLLYQEALEYRTK-RDEFRQLRRLKMPKEKIEERI 121
DE + + E +K ++ +L EA + D R+ L+ + + +
Sbjct: 357 SDEKVASDATLGEQEKRLHQLEEQLGTALSEASKNEVLIADLTREKENLRRMVDAELDNV 416
Query: 122 EKLEWELQTTPNISPEREKQIVDQIQVLATEL-EIIQQIERYNNKLQ--------EVRKK 172
KL+ E++ T S E + V I V +L ++ ++ER +KLQ +++
Sbjct: 417 NKLKQEIEVTQE-SLENSRSEVSDITVQLEQLRDLSSKLEREVSKLQMELEETRASLQRN 475
Query: 173 IDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREV 232
ID+ K + ++ E+ ++ +E+M + V + D ++V + +K
Sbjct: 476 IDETKHSSELLAAELTTTKELLKKTNEEMHTMSDELVAVSENRDSLQTELVNVYKKREHT 535
Query: 233 RRELREIERKILEYDQKHKELIAYKLV--ARMRAKRDVNFEKAVQALEKFKRGEKLTYDE 290
R EL++ E+ I+ ++ + + ++ +R + EKA ++L++ R +E
Sbjct: 536 RNELKQ-EKTIVRTLEEELKFLESQITREKELRKSLEDELEKATESLDEINRNVLALAEE 594
Query: 291 ILLLQRYN 298
+ L N
Sbjct: 595 LELATSRN 602
>emb|CAA98620.1| (Z74105) ORF YDL058w [Saccharomyces cerevisiae]
Length = 1268
Score = 69.5 bits (167), Expect = 4e-11
Identities = 56/253 (22%), Positives = 117/253 (46%), Gaps = 13/253 (5%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREK----AREFKA 64
EIK I LEE+ + N+ + E + KEL + + + V +L EK A +K
Sbjct: 392 EIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKD 451
Query: 65 KRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPK--EKIEERIE 122
+ E IK ++++++E + +L L Q ++ ++ E Q+ R + K E++++ I
Sbjct: 452 MQAENESLIKAVEESKNESSIQLSNL-QNKIDSMSQEKENFQIERGSIEKNIEQLKKTIS 510
Query: 123 KLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRA 182
LE + + S + + QI +L +LE E KI +L K R
Sbjct: 511 DLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTAN------DENVNKISELTKTREE 564
Query: 183 ISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERK 242
+ E+ N + ++ + + EVK+ + ++ ++L ++ E +++L +
Sbjct: 565 LEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRAN 624
Query: 243 ILEYDQKHKELIA 255
+ +++H++L A
Sbjct: 625 LESLEKEHEDLAA 637
>gi|9910570 sperm tail associated protein [Mus musculus]
>gi|5525095|dbj|BAA82514.1| (AB029919) sperm tail
associated protein [Mus musculus]
Length = 1022
Score = 69.5 bits (167), Expect = 4e-11
Identities = 56/294 (19%), Positives = 140/294 (47%), Gaps = 12/294 (4%)
Query: 9 EIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDE 68
++ ++++E ++ E+++ +L+EL EL+ ++ E L++ E + K DE
Sbjct: 540 QLHKLQKESSKIEEERKHNRQRLQELSSELSEGQRRLSNAEKEKSLLQKTLDEDEKKIDE 599
Query: 69 INQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKLEWE 127
+ + ++ + E+ + L +E LE + +E R QL++ K ++ +EE IE L E
Sbjct: 600 LFHSTQVSEQKQRELTNSIRKLEEELLEIKGLLEEKREQLKKSKEQEKALEEEIEALRQE 659
Query: 128 LQTTPNISPEREKQIVDQIQVLATEL-----EIIQQIERYNNK---LQEVRKKIDQLKKA 179
+ ++ E +++ ++ + L EL + + +YN+ +QE+ +I + K +
Sbjct: 660 AKRKEKMAKEHLRKLDEEKENLQAELTSRSSHLDSSLNKYNSSQKVIQELNAEIARQKDS 719
Query: 180 RRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREI 239
+ ++ + + + M+ + + +E+ +++ + + EK+ + E + +
Sbjct: 720 IMILQTQLDSAIQKEKNCFQNMV-SKEAYEELVRKSGNCQDDLTQALEKLTQATSETKSL 778
Query: 240 ERKILEYDQKHKELIAYKLVARMRAKRDVNFE-KAVQALEKFKRGEKLTYDEIL 292
R L+ Q+ K + ++ A + +N E K +Q ++ E +D+ L
Sbjct: 779 NRS-LQQTQERKAQLEDEIAAYEERMKKLNMELKKLQGFQQQSEQEVHNFDKKL 831
>gb|AAA48986.1| (M93676) nonmuscle myosin heavy chain [Gallus gallus]
Length = 1986
Score = 69.1 bits (166), Expect = 6e-11
Identities = 53/255 (20%), Positives = 119/255 (45%), Gaps = 20/255 (7%)
Query: 12 RIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQ 71
R E + E R E K L + L ++ ++E + K+LR + + +D++ +
Sbjct: 1476 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1535
Query: 72 RIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKL----EW 126
+ EL+K++ + Q+ E RT+ +E +L+ + K ++E ++ + E
Sbjct: 1536 NVHELEKSKRTLE-------QQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1588
Query: 127 ELQTTPNISPEREKQIVDQIQVLATELE--------IIQQIERYNNKLQEVRKKIDQLKK 178
+LQ + E+++ +V Q++ L ELE + ++ L+++ +I+ K
Sbjct: 1589 DLQARDEQNEEKKRMLVKQVRELEAELEDERKQRALAVAAKKKMEMDLKDLEGQIEAANK 1648
Query: 179 ARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELRE 238
AR ++++L Q + + ++ + DE+ ++ E +K+ L +I +++ E
Sbjct: 1649 ARDEAIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKGLEAEILQLQEEFAA 1708
Query: 239 IERKILEYDQKHKEL 253
ER +Q+ EL
Sbjct: 1709 SERARRHAEQERDEL 1723
>gb|AAA48987.1| (M93676) nonmuscle myosin heavy chain [Gallus gallus]
Length = 1997
Score = 69.1 bits (166), Expect = 6e-11
Identities = 53/255 (20%), Positives = 119/255 (45%), Gaps = 20/255 (7%)
Query: 12 RIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQ 71
R E + E R E K L + L ++ ++E + K+LR + + +D++ +
Sbjct: 1487 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1546
Query: 72 RIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKL----EW 126
+ EL+K++ + Q+ E RT+ +E +L+ + K ++E ++ + E
Sbjct: 1547 NVHELEKSKRTLE-------QQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1599
Query: 127 ELQTTPNISPEREKQIVDQIQVLATELE--------IIQQIERYNNKLQEVRKKIDQLKK 178
+LQ + E+++ +V Q++ L ELE + ++ L+++ +I+ K
Sbjct: 1600 DLQARDEQNEEKKRMLVKQVRELEAELEDERKQRALAVAAKKKMEMDLKDLEGQIEAANK 1659
Query: 179 ARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELRE 238
AR ++++L Q + + ++ + DE+ ++ E +K+ L +I +++ E
Sbjct: 1660 ARDEAIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKGLEAEILQLQEEFAA 1719
Query: 239 IERKILEYDQKHKEL 253
ER +Q+ EL
Sbjct: 1720 SERARRHAEQERDEL 1734
>pir||B43402 myosin heavy chain-B, neuronal - chicken >gi|212452|gb|AAA48988.1|
(M93676) nonmuscle myosin heavy chain [Gallus gallus]
Length = 2007
Score = 69.1 bits (166), Expect = 6e-11
Identities = 53/255 (20%), Positives = 119/255 (45%), Gaps = 20/255 (7%)
Query: 12 RIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQ 71
R E + E R E K L + L ++ ++E + K+LR + + +D++ +
Sbjct: 1497 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1556
Query: 72 RIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKL----EW 126
+ EL+K++ + Q+ E RT+ +E +L+ + K ++E ++ + E
Sbjct: 1557 NVHELEKSKRTLE-------QQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1609
Query: 127 ELQTTPNISPEREKQIVDQIQVLATELE--------IIQQIERYNNKLQEVRKKIDQLKK 178
+LQ + E+++ +V Q++ L ELE + ++ L+++ +I+ K
Sbjct: 1610 DLQARDEQNEEKKRMLVKQVRELEAELEDERKQRALAVAAKKKMEMDLKDLEGQIEAANK 1669
Query: 179 ARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELRE 238
AR ++++L Q + + ++ + DE+ ++ E +K+ L +I +++ E
Sbjct: 1670 ARDEAIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKGLEAEILQLQEEFAA 1729
Query: 239 IERKILEYDQKHKEL 253
ER +Q+ EL
Sbjct: 1730 SERARRHAEQERDEL 1744
>pir||T41023 probable nuclear pore complex-associated protein - fission yeast
(Schizosaccharomyces pombe) >gi|3218398|emb|CAA19588.1|
(AL023860) putative nuclear pore complex-associated
protein [Schizosaccharomyces pombe]
Length = 1837
Score = 69.1 bits (166), Expect = 6e-11
Identities = 63/282 (22%), Positives = 125/282 (43%), Gaps = 37/282 (13%)
Query: 4 KVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFK 63
+VDP +++ +K+ E L EK+ +E KL+E KE + + Q+ + N EV+ L+++ +
Sbjct: 1348 RVDPTQLEELKKNCEALEKEKQELETKLQETAKETDTFKQQVNSLNEEVENLKKEVEQAN 1407
Query: 64 AKRDEI----NQRIKELKKN--------RDEINAKLDLLYQEALEYRTKRDEFRQLR--- 108
K + N++ + LKK+ + E+ K L + E + E L+
Sbjct: 1408 TKNTRLAAAWNEKCENLKKSSLTRFAHLKQELTNKNKELTSKNAENEAMQKEIESLKDSN 1467
Query: 109 -RLKMPKEKIEERIEKLEWELQTTPNISPERE----KQIVDQIQVLATELEIIQQIERYN 163
+L+ E+I K ++E + E+E K ++ +Q A + + +I
Sbjct: 1468 HQLQESASSDAEQITKEQFEQLKSEKERTEKELADSKNELEHLQSEAVDADGKTEISNLE 1527
Query: 164 NKLQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKK------EADE 217
++ E+R + L + + +S E+ L H + + ADE+ + +
Sbjct: 1528 KEIHELRSDKEGLVQQVQNLSAELAALRE-----HSPTQGSLENADEIARLRSQLESTKQ 1582
Query: 218 YHQKVVELR------EKIREVRRELREIERKILEYDQKHKEL 253
Y++K E E + E + E+E ++ E Q+ KEL
Sbjct: 1583 YYEKEKETEILAARSELVAEKEKTKEELENQLNEKSQRIKEL 1624
>gb|AAA48985.1| (M93676) nonmuscle myosin heavy chain [Gallus gallus]
Length = 1976
Score = 69.1 bits (166), Expect = 6e-11
Identities = 53/255 (20%), Positives = 119/255 (45%), Gaps = 20/255 (7%)
Query: 12 RIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQ 71
R E + E R E K L + L ++ ++E + K+LR + + +D++ +
Sbjct: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525
Query: 72 RIKELKKNRDEINAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKL----EW 126
+ EL+K++ + Q+ E RT+ +E +L+ + K ++E ++ + E
Sbjct: 1526 NVHELEKSKRTLE-------QQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1578
Query: 127 ELQTTPNISPEREKQIVDQIQVLATELE--------IIQQIERYNNKLQEVRKKIDQLKK 178
+LQ + E+++ +V Q++ L ELE + ++ L+++ +I+ K
Sbjct: 1579 DLQARDEQNEEKKRMLVKQVRELEAELEDERKQRALAVAAKKKMEMDLKDLEGQIEAANK 1638
Query: 179 ARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELRE 238
AR ++++L Q + + ++ + DE+ ++ E +K+ L +I +++ E
Sbjct: 1639 ARDEAIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKGLEAEILQLQEEFAA 1698
Query: 239 IERKILEYDQKHKEL 253
ER +Q+ EL
Sbjct: 1699 SERARRHAEQERDEL 1713
>pir||A59282 nonmuscle myosin II heavy chain A - African clawed frog
>gi|3660672|gb|AAC83556.1| (AF055895) nonmuscle myosin II
heavy chain A [Xenopus laevis]
Length = 1964
Score = 69.1 bits (166), Expect = 6e-11
Identities = 53/268 (19%), Positives = 132/268 (48%), Gaps = 24/268 (8%)
Query: 10 IKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEI 69
+++ +++ ++L E++ I K + + ++++ K L + R E+A E KA+ + +
Sbjct: 1439 LEKKQKKFDQLLGEEKAISAKYADERDRSEAEAREKETKALALARALEEALEAKAELERL 1498
Query: 70 NQRIK----ELKKNRDEINAKLD-------LLYQEALEYRTKRDEFR-QLRRLKMPKEKI 117
N++++ +L ++D++ + L Q+A E +T+ +E +L+ + K ++
Sbjct: 1499 NKQLRTEMEDLVSSKDDVGKSVHELEKSKRALEQQAEEMKTQLEELEDELQATEDAKLRL 1558
Query: 118 EERIEKL----EWELQTTPNISPEREKQIVDQIQVLATELE--------IIQQIERYNNK 165
E ++ + E +LQ S +++KQ+V Q++ + ELE + ++
Sbjct: 1559 EVNLQAMKAQFERDLQGRDEQSEDKKKQLVRQVKEMEAELEDERKQRSLAVAARKKLEMD 1618
Query: 166 LQEVRKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVEL 225
L+++ +ID K R ++++L Q + + ++ T D++ ++ E +K+ +
Sbjct: 1619 LKDLEGQIDSSNKNREDAIKQLRKLQAQIKDYQRELEDTRASRDDILSQSKESEKKLKSM 1678
Query: 226 REKIREVRRELREIERKILEYDQKHKEL 253
++ ++ EL ER + Q+ EL
Sbjct: 1679 EAEMIHMQEELAAAERGKRQAQQERDEL 1706
>pir||S21801 myosin heavy chain, neuronal [similarity] - rat
Length = 1999
Score = 68.7 bits (165), Expect = 8e-11
Identities = 54/264 (20%), Positives = 121/264 (45%), Gaps = 12/264 (4%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKARE 61
Q K D + I + + R+ E + E+ KEL++ + + + + LR+ +E
Sbjct: 1443 QKKFDQLLAEEITKSAKYAEERARDAEERAEKATKELSLARAELEAMEQKAEFLRKNLQE 1502
Query: 62 FKAKRDEINQRIKELKKNRDEINAKL---DLLYQEALEYRTKRDEFRQLRRLKMPKE-KI 117
+ DE++ ++ + K + +KL + +E + + DE Q K+ E +
Sbjct: 1503 MTERLDEMSSKVDDAKSVLEHEKSKLGREQQVMEEKTQLLEEEDELAQTEDAKLRLEVNL 1562
Query: 118 EERIEKLEWELQTTPNISPEREKQIVDQIQVLATELEIIQQ--------IERYNNKLQEV 169
+ + E +LQ + S E++K++V Q++ + ELE ++ +++ L+++
Sbjct: 1563 QAMKAQFERDLQGRQDDSEEKQKKLVRQVREMEAELEDQRKEMSRARAAVKKLEMDLKDL 1622
Query: 170 RKKIDQLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKI 229
ID K R ++++ L Q + ++ T +E+ +A E +K+ + ++
Sbjct: 1623 EAHIDSANKNRDEAKIQLRNLQAQMKDCMRELDDTRASREEIALQAKENEKKLKSMEAEM 1682
Query: 230 REVRRELREIERKILEYDQKHKEL 253
+++ EL ER + Q+ EL
Sbjct: 1683 IQLQEELAAAERAKRQAQQERDEL 1706
>sp|P15924|DESP_HUMAN DESMOPLAKIN I AND II (DPI AND DPII) >gi|181608|gb|AAA35766.1|
(J05211) desmoplakin [Homo sapiens]
Length = 1752
Score = 68.7 bits (165), Expect = 8e-11
Identities = 66/293 (22%), Positives = 132/293 (44%), Gaps = 17/293 (5%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKA--REFKAK 65
++ K ++ +L+ L E R+++ ++ L + ++R + E L++KA E K
Sbjct: 111 DDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQR--RRAEENALQQKACGSEIMQK 168
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
+ + +K++ + R E NA+ +EA +T +D+ +++ RLK ++ +R + E
Sbjct: 169 KQHLEIELKQVMQQRSEDNARHKQSLEEAA--KTIQDKNKEIERLKAEFQEEAKRRWEYE 226
Query: 126 WELQTTPNISPEREKQIVDQI--QVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAI 183
EL N E + +Q ++ T+ I Q + R +ID L + R++
Sbjct: 227 NELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSL 286
Query: 184 SMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKI 243
S EI++L N Q E + + + + K E Q+ +L ++R+V + E +
Sbjct: 287 SEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE---ES 343
Query: 244 LEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQR 296
+ Y Q + A+ ++ E+ Q ++K K DE LQR
Sbjct: 344 VRYKQSLDD------AAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQR 390
>gi|4758200 desmoplakin (DPI, DPII); Desmoplakin [Homo sapiens]
>gi|1147813|gb|AAA85135.1| (M77830) desmoplakin I [Homo
sapiens]
Length = 2871
Score = 68.7 bits (165), Expect = 8e-11
Identities = 66/293 (22%), Positives = 132/293 (44%), Gaps = 17/293 (5%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKA--REFKAK 65
++ K ++ +L+ L E R+++ ++ L + ++R + E L++KA E K
Sbjct: 1230 DDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQR--RRAEENALQQKACGSEIMQK 1287
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
+ + +K++ + R E NA+ +EA +T +D+ +++ RLK ++ +R + E
Sbjct: 1288 KQHLEIELKQVMQQRSEDNARHKQSLEEAA--KTIQDKNKEIERLKAEFQEEAKRRWEYE 1345
Query: 126 WELQTTPNISPEREKQIVDQI--QVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAI 183
EL N E + +Q ++ T+ I Q + R +ID L + R++
Sbjct: 1346 NELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSL 1405
Query: 184 SMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKI 243
S EI++L N Q E + + + + K E Q+ +L ++R+V + E +
Sbjct: 1406 SEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE---ES 1462
Query: 244 LEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQR 296
+ Y Q + A+ ++ E+ Q ++K K DE LQR
Sbjct: 1463 VRYKQSLDD------AAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQR 1509
>pir||A38194 desmoplakin I - human
Length = 2677
Score = 68.7 bits (165), Expect = 8e-11
Identities = 66/293 (22%), Positives = 132/293 (44%), Gaps = 17/293 (5%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKA--REFKAK 65
++ K ++ +L+ L E R+++ ++ L + ++R + E L++KA E K
Sbjct: 1036 DDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQR--RRAEENALQQKACGSEIMQK 1093
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
+ + +K++ + R E NA+ +EA +T +D+ +++ RLK ++ +R + E
Sbjct: 1094 KQHLEIELKQVMQQRSEDNARHKQSLEEAA--KTIQDKNKEIERLKAEFQEEAKRRWEYE 1151
Query: 126 WELQTTPNISPEREKQIVDQI--QVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAI 183
EL N E + +Q ++ T+ I Q + R +ID L + R++
Sbjct: 1152 NELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSL 1211
Query: 184 SMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKI 243
S EI++L N Q E + + + + K E Q+ +L ++R+V + E +
Sbjct: 1212 SEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE---ES 1268
Query: 244 LEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQR 296
+ Y Q + A+ ++ E+ Q ++K K DE LQR
Sbjct: 1269 VRYKQSLDD------AAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQR 1315
>emb|CAA19927.1| (AL031058) dJ512B11.1 (Desmoplakin I (DPI)) [Homo sapiens]
Length = 2871
Score = 68.7 bits (165), Expect = 8e-11
Identities = 66/293 (22%), Positives = 132/293 (44%), Gaps = 17/293 (5%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKA--REFKAK 65
++ K ++ +L+ L E R+++ ++ L + ++R + E L++KA E K
Sbjct: 1230 DDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQR--RRAEENALQQKACGSEIMQK 1287
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
+ + +K++ + R E NA+ +EA +T +D+ +++ RLK ++ +R + E
Sbjct: 1288 KQHLEIELKQVMQQRSEDNARHKQSLEEAA--KTIQDKNKEIERLKAEFQEEAKRRWEYE 1345
Query: 126 WELQTTPNISPEREKQIVDQI--QVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAI 183
EL N E + +Q ++ T+ I Q + R +ID L + R++
Sbjct: 1346 NELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSL 1405
Query: 184 SMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKI 243
S EI++L N Q E + + + + K E Q+ +L ++R+V + E +
Sbjct: 1406 SEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE---ES 1462
Query: 244 LEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQR 296
+ Y Q + A+ ++ E+ Q ++K K DE LQR
Sbjct: 1463 VRYKQSLDD------AAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQR 1509
>gi|11418894 desmoplakin (DPI, DPII) [Homo sapiens]
Length = 2463
Score = 68.7 bits (165), Expect = 8e-11
Identities = 66/293 (22%), Positives = 132/293 (44%), Gaps = 17/293 (5%)
Query: 8 EEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKA--REFKAK 65
++ K ++ +L+ L E R+++ ++ L + ++R + E L++KA E K
Sbjct: 822 DDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQR--RRAEENALQQKACGSEIMQK 879
Query: 66 RDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLE 125
+ + +K++ + R E NA+ +EA +T +D+ +++ RLK ++ +R + E
Sbjct: 880 KQHLEIELKQVMQQRSEDNARHKQSLEEAA--KTIQDKNKEIERLKAEFQEEAKRRWEYE 937
Query: 126 WELQTTPNISPEREKQIVDQI--QVLATELEIIQQIERYNNKLQEVRKKIDQLKKARRAI 183
EL N E + +Q ++ T+ I Q + R +ID L + R++
Sbjct: 938 NELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSL 997
Query: 184 SMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKI 243
S EI++L N Q E + + + + K E Q+ +L ++R+V + E +
Sbjct: 998 SEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE---ES 1054
Query: 244 LEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEILLLQR 296
+ Y Q + A+ ++ E+ Q ++K K DE LQR
Sbjct: 1055 VRYKQSLDD------AAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQR 1101
>gi|5453820 nuclear mitotic apparatus protein 1 [Homo sapiens]
>gi|284337|pir||A42184 nuclear mitotic apparatus protein
NuMA - human >gi|35121|emb|CAA77670.1| (Z11584) NuMA
protein [Homo sapiens]
Length = 2101
Score = 68.3 bits (164), Expect = 1e-10
Identities = 71/312 (22%), Positives = 152/312 (47%), Gaps = 40/312 (12%)
Query: 15 RELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIK 74
++LE L EK KLE LQ++L + + RD V + + + E K +E+ ++
Sbjct: 604 KQLEALEKEKA---AKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE 660
Query: 75 ELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWELQTTPNI 134
++ + E A++ L L+ R+++ + + R+ K++++E+++ L+ L+ T
Sbjct: 661 TARQEQHEAQAQVAEL---ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGS 717
Query: 135 SPEREKQIVDQI--------QVLATELEIIQQIERYNNKLQEVR-------KKIDQLKKA 179
E +++ D + ++ A +++Q +R +L+E R ++ QL +A
Sbjct: 718 LEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLLQLGEA 777
Query: 180 RRAISMEI-QQLANQSQQFH------EQMIKTYQK-----ADEVKKEAD---EYHQKVVE 224
+A + + ++LA H EQ++K D ++EA + ++++
Sbjct: 778 HQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRDGYEDSQQEEAQYGAMFQEQLMT 837
Query: 225 LREKIREVRRELREIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQAL-EKFKRG 283
L+E+ + R+EL+E + K+ + H EL + ++ A+ N +A+Q + EK R
Sbjct: 838 LKEECEKARQELQEAKEKVAGI-ESHSELQISRQQNKL-AELHANLARALQQVQEKEVRA 895
Query: 284 EKLTYDEILLLQ 295
+KL D++ LQ
Sbjct: 896 QKLA-DDLSTLQ 906
>sp|P08799|MYS2_DICDI MYOSIN II HEAVY CHAIN, NON MUSCLE >gi|84128|pir||A26655 myosin heavy
chain [similarity] - slime mold (Dictyostelium
discoideum) >gi|167835|gb|AAA33227.1| (M14628) myosin
heavy chain [Dictyostelium discoideum]
Length = 2116
Score = 68.3 bits (164), Expect = 1e-10
Identities = 69/294 (23%), Positives = 136/294 (45%), Gaps = 59/294 (20%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKARE 61
Q+K + E +K + + L +KR +E+++E+++ EL DEK L ++ L+ + R
Sbjct: 871 QLKAEKETLKAMYDSKDALEAQKRELEIRVEDMESEL-------DEKKLALENLQNQKRS 923
Query: 62 FKAKRDEINQRIKELKKNRDEINAKLDLLYQEALE--YRTKRDEFRQLRRLKMPKEKIEE 119
+ K ++ + ++E +K R+ + KL Y+E LE R + + RL+ K+++++
Sbjct: 924 VEEKVRDLEEELQEEQKLRNTLE-KLKKKYEEELEEMKRVNDGQSDTISRLEKIKDELQK 982
Query: 120 RIEKLEWELQTTPNISPE-REKQIVDQIQV-LATELEII-----------QQIERYNNKL 166
+E+L T + S E ++K ++++ +V L +EL+ + ++ R KL
Sbjct: 983 EVEEL------TESFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSELLRQKKKL 1036
Query: 167 QEVRKKIDQLKKARRAISMEIQQLANQSQQ--------------------------FHEQ 200
+E K++ + A A + Q+ AN+ Q Q
Sbjct: 1037 EEELKQVQEALAAETAAKL-AQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQ 1095
Query: 201 MIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREI--ERKILEYDQKHKE 252
++ + DE KK D +K L + E++ +L E+K L YD K K+
Sbjct: 1096 LVAVNNELDEEKKNRDALEKKKKALDAMLEEMKDQLESTGGEKKSL-YDLKVKQ 1148
>sp|Q99105|MYSU_RABIT MYOSIN HEAVY CHAIN, EMBRYONIC SMOOTH MUSCLE ISOFORM
>gi|109319|pir||A38650 myosin heavy chain, embryonic
smooth muscle - rabbit (fragment)
>gi|217730|dbj|BAA01124.1| (D10280) myosin heavy chain
[Oryctolagus sp.]
Length = 501
Score = 68.3 bits (164), Expect = 1e-10
Identities = 52/244 (21%), Positives = 115/244 (46%), Gaps = 20/244 (8%)
Query: 23 EKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRDEINQRIKELKKNRDE 82
E R E K L + L ++ ++E + K+LR + + +D++ + + EL+K++
Sbjct: 2 EAREKETKALSLSRALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA 61
Query: 83 INAKLDLLYQEALEYRTKRDEFR-QLRRLKMPKEKIEERIEKL----EWELQTTPNISPE 137
+ Q+ E RT+ +E +L+ + K ++E + + E +LQ S E
Sbjct: 62 LE-------QQVEEMRTQLEELEDELQATEDAKLRLEVNTQAMKAQFERDLQARDEQSEE 114
Query: 138 REKQIVDQIQVLATELE--------IIQQIERYNNKLQEVRKKIDQLKKARRAISMEIQQ 189
+++ + Q++ L ELE + ++ L+++ +I+ KAR ++++
Sbjct: 115 KKRLLTKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARERRVKQLRR 174
Query: 190 LANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRRELREIERKILEYDQK 249
L Q + + ++ + DE+ ++ E +K+ L +I +++ EL ER +Q+
Sbjct: 175 LQAQMKDYQRELEEARGSRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQE 234
Query: 250 HKEL 253
EL
Sbjct: 235 RDEL 238
>gi|7662062 KIAA0336 gene product [Homo sapiens] >gi|2224613|dbj|BAA20794.1|
(AB002334) KIAA0336 [Homo sapiens]
Length = 1583
Score = 68.3 bits (164), Expect = 1e-10
Identities = 64/258 (24%), Positives = 133/258 (50%), Gaps = 33/258 (12%)
Query: 25 RNIELKLEELQKELNIWVQKRDEKNLEVKRLREKA-REFKAKRDE---INQRIKELKKNR 80
+ +E K+E L+KE ++++EK ++K + KA +E + R E + + ++ L+ +
Sbjct: 846 KELEEKIENLEKE----CKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEK 901
Query: 81 DEINAKLDLLYQEALEYRTKRDEF-RQLRRLKMPKEK---IEERIEKLEWELQTT----P 132
D+++A + L Q A Y+ E+ +Q +L + KE+ E RIE L +L+ +
Sbjct: 902 DQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCE 961
Query: 133 NISPEREKQI--VDQIQVLATELEI-IQQIER----YNNKLQEVRKKIDQLKKARRAISM 185
I+ + E + ++ +Q A LE+ I +++R + +L+ + + +Q K
Sbjct: 962 TINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVN 1021
Query: 186 EIQQLANQSQQFHEQMIKTYQKADEVKKEAD----------EYHQKVVELREKIREVRRE 235
E+++L Q Q+ +Q+ KT Q+ + VKK+A +Y + + EL +K+ +
Sbjct: 1022 ELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNK 1081
Query: 236 LREIERKILEYDQKHKEL 253
+ ++E++I QK + L
Sbjct: 1082 IEDLEQEIKIQKQKQETL 1099
>gb|AAD12213.1| (AC006135) putative vicilin storage protein (globulin-like)
[Arabidopsis thaliana]
Length = 699
Score = 68.3 bits (164), Expect = 1e-10
Identities = 69/284 (24%), Positives = 138/284 (48%), Gaps = 33/284 (11%)
Query: 9 EIKRIKRELEEL-HNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREKAREFKAKRD 67
E+ ++ RE+EE E+ IE + +E ++ KR E+ E KR E+ E K KR+
Sbjct: 416 ELSKLMREIEERKRREEEEIERRRKEEEEARKREEAKRREEE-EAKRREEEETERK-KRE 473
Query: 68 EINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEERIEKLEWE 127
E R +E ++ R+E AK + E + + +E Q R+ + +EK EE +K E E
Sbjct: 474 EEEARKREEERKREEEEAK-----RREEERKKREEEAEQARKREEEREKEEEMAKKREEE 528
Query: 128 LQTTPNISPEREKQIV-------------DQIQVLATELEIIQQIERYNNKLQEVRKKID 174
Q ER+++ ++ + E+ ++ ER + +EV +KI
Sbjct: 529 RQRKEREEVERKRREEQERKRREEEARKREEERKREEEMAKRREQERQRKEREEVERKIR 588
Query: 175 QLKKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRR 234
+ ++ +R +++A + +Q ++ + + + ++EA + +++ ++RE+ R+ R+
Sbjct: 589 EEQERKRE-----EEMAKRREQERQKKEREEMERKKREEEARKREEEMAKIREEERQ-RK 642
Query: 235 ELREIERKILE------YDQKHKELIAYKLVARMRAKRDVNFEK 272
E ++ERK E +++ +E A K R K++ EK
Sbjct: 643 EREDVERKRREEEAMRREEERKREEEAAKRAEEERRKKEEEEEK 686
>dbj|BAA93660.1| (AB026497) myosin containing PDZ domain [Mus musculus]
Length = 2035
Score = 68.3 bits (164), Expect = 1e-10
Identities = 57/296 (19%), Positives = 136/296 (45%), Gaps = 32/296 (10%)
Query: 2 QVKVDPEEIKRIKRELEELHNEKRNIELKLEELQKELNIWVQKRDEKNLEVKRLREK-AR 60
Q D + ++K++L +L + ++ E +L+E + + Q + +E++R+R+ ++
Sbjct: 1525 QESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGSIQMLEQAKLRLEMEMERMRQTHSK 1584
Query: 61 EFKAKRDEINQRIKELKKNRDEINAKLDLLYQEALEYRTKRDEFRQLRRLKMPKEKIEER 120
E +++ +E+ + + +K ++ +L+ EY K+ R+ R L+ + ++
Sbjct: 1585 EMESRDEEVEEARQSCQKKLKQMEVQLEE------EYEDKQKALREKRELESKLSTLSDQ 1638
Query: 121 IEKLEWELQTTPNISPEREKQIVDQIQVLATELE----IIQQIERYNNKLQEVRKKIDQL 176
+ + ++E + +R K ++ Q++ L+ ++I + N+L+E
Sbjct: 1639 VNQRDFESEKRLRKDLKRTKALLADAQIMLDHLKNNAPSKREIAQLKNQLEESEFTCAAA 1698
Query: 177 KKARRAISMEIQQLANQSQQFHEQMIKTYQKADEVKKEADEYHQKVVELREKIREVRREL 236
KAR+A+ +E++ L + + D++ K +++ L+ + E++ L
Sbjct: 1699 VKARKAMEVEMEDL--------------HLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1744
Query: 237 REIERKILEYDQKHKELIAYKLVARMRAKRDVNFEKAVQALEKFKRGEKLTYDEIL 292
E + + E +KHK +A +A RD+ +QA + EK E L
Sbjct: 1745 EEDQEDMNELMKKHKAAVA-------QASRDMAQMNDLQAQIEESNKEKQELQEKL 1793
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.315 0.133 0.344
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96503867
Number of Sequences: 2977
Number of extensions: 4041376
Number of successful extensions: 68687
Number of sequences better than 1.0e-10: 75
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 65760
Number of HSP's gapped (non-prelim): 941
length of query: 300
length of database: 189,106,746
effective HSP length: 64
effective length of query: 236
effective length of database: 150,803,578
effective search space: 35589644408
effective search space used: 35589644408
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (22.0 bits)
S2: 164 (68.3 bits)