BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0084 (napA-1) DE:Na+/H+ antiporter (napA-1)
(375 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abys... 718 0.0
pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus hori... 634 0.0
pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus hori... 315 6e-85
pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abys... 312 5e-84
gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus] 248 9e-65
gb|AAB40041.1| (U17283) putative spore germination apparatus pro... 230 2e-59
sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A4211... 217 2e-55
emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus la... 192 5e-48
pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus hori... 180 3e-44
pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abys... 177 2e-43
pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298... 170 2e-41
pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp... 169 4e-41
pir||C82955 probable sodium/proton antiporter PA5529 [imported] ... 161 1e-38
pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abys... 152 6e-36
pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii... 145 1e-33
pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus hori... 144 1e-33
pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spir... 138 1e-31
dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans] 135 7e-31
gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40... 129 5e-29
pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC... 129 7e-29
pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis >... 128 1e-28
gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum] 116 4e-25
pir||C70474 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298... 116 5e-25
emb|CAB45049.1| (AL078635) putative integral membrane ion antipo... 113 3e-24
pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana... 113 5e-24
pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp... 111 1e-23
gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter ... 109 4e-23
gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana] 109 4e-23
pir||T50062 Probable K+/H+-antiporter [imported] - fission yeast... 109 4e-23
pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thalian... 108 9e-23
dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabi... 108 9e-23
dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arab... 108 2e-22
gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus] ... 107 3e-22
gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus] 102 9e-21
pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis >... 101 1e-20
dbj|BAA06982.1| (D32253) MagA [Magnetospirillum sp.] 100 3e-20
pir||C71934 glutathione-regulated potassium-efflux system protei... 100 3e-20
pir||A81330 probable glutathione-regulated potassium-efflux syst... 100 3e-20
pir||G64578 glutathione-regulated potassium-efflux system protei... 95 1e-18
gb|AAF69026.1| (AF182516) unknown [Pseudomonas putida] 95 1e-18
pir||B82056 glutathione-regulated potassium-efflux system protei... 94 3e-18
pir||D71642 glutathione-regulated potassium-efflux system protei... 93 4e-18
pir||C83496 glutathione-regulated potassium-efflux system protei... 93 4e-18
sp|P44933|KEFX_HAEIN GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYST... 92 7e-18
sp|P45522|KEFB_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYST... 92 1e-17
pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298... 92 1e-17
sp|P03819|KEFC_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYST... 92 1e-17
pir||G75431 probable Na+/H+ antiporter - Deinococcus radiodurans... 91 2e-17
pir||G75282 probable glutathione-regulated potassium-efflux syst... 90 3e-17
pir||H81265 probable transmembrane transport protein Cj1684c [im... 88 1e-16
pir||B69146 gluthatione-regulated K+/H+ antiporter - Methanobact... 87 2e-16
gb|AAD01191.1| (AF003382) KEA1 [Arabidopsis thaliana] 87 3e-16
gb|AAF78418.1|AC009273_24 (AC009273) Identical to K efflux antip... 86 6e-16
pir||F70591 probable kefB protein - Mycobacterium tuberculosis (... 84 3e-15
pir||T01227 glutathione-regulated potassium-efflux system protei... 83 4e-15
dbj|BAB11240.1| (AB010074) potassium/proton antiporter-like prot... 83 5e-15
gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus] 83 6e-15
pir||B81225 glutathione-regulated potassium-efflux system protei... 83 6e-15
pir||C81997 probable glutathione-regulated potassium-efflux syst... 83 6e-15
emb|CAB76285.1| (AL158057) putative transmembrane transport prot... 81 2e-14
emb|CAB44437.1| (AJ242913) glutathione-gated K efflux system [Kl... 80 5e-14
gb|AAD03448.1| (AF118223) contains similarity several bacterial ... 79 9e-14
pir||T36239 probable integral membrane efflux protein - Streptom... 79 9e-14
sp|P39830|YBAL_ECOLI HYPOTHETICAL 59.4 KD PROTEIN IN GSK-FSR INT... 75 1e-12
emb|CAC12310.1| (AL445066) Na+/H+ antiporter related protein [Th... 75 1e-12
pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum perni... 75 1e-12
pir||F69201 conserved hypothetical protein MTH760 - Methanobacte... 74 2e-12
pir||F82595 glutathione-regulated potassium efflux system protei... 74 3e-12
gb|AAD30610.1|AC007153_2 (AC007153) similar to Na/H antiporter p... 73 4e-12
pir||E82956 probable potassium efflux transporter PA5518 [import... 73 5e-12
pir||JC5342 Na+/H+ antiporter cdu2 - Clostridium difficile >gi|1... 72 1e-11
pir||T35102 probable transmembrane transport protein - Streptomy... 72 1e-11
gb|AAC60780.1| (U46859) RosB [Yersinia enterocolitica (type 0:8)] 70 4e-11
dbj|BAB07757.1| (AP001520) Na+/H+ antiporter [Bacillus halodurans] 70 4e-11
gb|AAA84962.1| (U37008) KefC [Myxococcus xanthus] 70 5e-11
pir||H71848 probable na+/h+ antiporter - Helicobacter pylori (st... 69 8e-11
>pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abyssi (strain
Orsay) >gi|5457567|emb|CAB49058.1| (AJ248283) Na+/H+
antiporter (napA-1) [Pyrococcus abyssi]
Length = 375
Score = 718 bits (1832), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIERNEIIVEFANLGVLML 60
METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIERNEIIVEFANLGVLML
Sbjct: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIERNEIIVEFANLGVLML 60
Query: 61 LFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLYGAIMTPTSV 120
LFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLYGAIMTPTSV
Sbjct: 61 LFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLYGAIMTPTSV 120
Query: 121 SITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEV 180
SITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEV
Sbjct: 121 SITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEV 180
Query: 181 AGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLI 240
AGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLI
Sbjct: 181 AGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLI 240
Query: 241 GLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISK 300
GLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISK
Sbjct: 241 GLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISK 300
Query: 301 VIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLT 360
VIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLT
Sbjct: 301 VIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLT 360
Query: 361 TLITPIMLRKTYIIT 375
TLITPIMLRKTYIIT
Sbjct: 361 TLITPIMLRKTYIIT 375
>pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
>gi|3256522|dbj|BAA29205.1| (AP000001) 375aa long
hypothetical Na(+)/H(+) antiporter [Pyrococcus
horikoshii]
Length = 375
Score = 634 bits (1617), Expect = 0.0
Identities = 307/374 (82%), Positives = 356/374 (95%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIERNEIIVEFANLGVLML 60
METLL+LA++LAVAK SGW+FE+FNQPIVLGQI+AG++MGL+IERNEII+EFANLGVLML
Sbjct: 1 METLLLLAILLAVAKFSGWIFEKFNQPIVLGQILAGILMGLIIERNEIIIEFANLGVLML 60
Query: 61 LFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLYGAIMTPTSV 120
LFLAG+ESD EEFK+VG+P ILVA VGVLFAF+FGF++AYPFFDFGTA+LYGA+MTPTSV
Sbjct: 61 LFLAGIESDLEEFKKVGKPGILVAGVGVLFAFIFGFIVAYPFFDFGTAMLYGAVMTPTSV 120
Query: 121 SITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEV 180
SITVKVLMELGKLRT+EG TILAAAV+DDVLGIL+LTIVIS LREGSVHYD+I+++LLEV
Sbjct: 121 SITVKVLMELGKLRTREGTTILAAAVIDDVLGILVLTIVISTLREGSVHYDIILKILLEV 180
Query: 181 AGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLI 240
AGFLAVFLY+GPV ME+ FRRLSK+DLPE+TT+FA+VFLVLFAYLAEHLNLASILGAYLI
Sbjct: 181 AGFLAVFLYIGPVFMEDAFRRLSKIDLPEATTTFAVVFLVLFAYLAEHLNLASILGAYLI 240
Query: 241 GLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISK 300
GLSIGQTSYKKRIE MN +GYSIFIP+FFV+VGMRIDPRFL +AK FA LYA+ AM+SK
Sbjct: 241 GLSIGQTSYKKRIEDHMNTLGYSIFIPLFFVDVGMRIDPRFLLQAKVFALLYALIAMLSK 300
Query: 301 VIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLT 360
VIGCGLGAYL+ FDW++S+KIGIGMIPRLGVELAMI+TAMA+G+AGSDVLTVAMTMVFLT
Sbjct: 301 VIGCGLGAYLANFDWKSSLKIGIGMIPRLGVELAMITTAMASGIAGSDVLTVAMTMVFLT 360
Query: 361 TLITPIMLRKTYII 374
TL+TP++L++ Y I
Sbjct: 361 TLVTPLLLKRIYQI 374
>pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
>gi|3256692|dbj|BAA29375.1| (AP000001) 380aa long
hypothetical Na(+)/H(+) antiporter [Pyrococcus
horikoshii]
Length = 380
Score = 315 bits (798), Expect = 6e-85
Identities = 167/377 (44%), Positives = 244/377 (64%), Gaps = 5/377 (1%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLG 56
M LL LA++L VAKL G++ + P LGQ+I G+I+G ++E ++ + A LG
Sbjct: 1 MNVLLELAIILVVAKLFGYLMVKLGFPAALGQLIGGIIIGPSLLNIVEYSQEVRFLAELG 60
Query: 57 VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIM 115
V++LLFLAGLE+D EEFK VG + +VA++GV FL G+LIA + + AL G I+
Sbjct: 61 VIILLFLAGLETDVEEFKHVGLSAFIVATMGVFVPFLLGYLIAIVYGYRSLAALFLGGIL 120
Query: 116 TPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVE 175
T TSV +T +LME+ KLRTK G TILAAA+VDDVLGI+ILTI+++M G V I
Sbjct: 121 TATSVGLTTSILMEMKKLRTKVGTTILAAAIVDDVLGIIILTILVAMSSRGRVEIFDIEI 180
Query: 176 VLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASIL 235
+L EV F + +++G +++ V K+ LPE+ T+FAIV ++LFAYLAE LA I
Sbjct: 181 ILAEVIIFFLLGIFIGHPIVKEVLMLSEKITLPETVTTFAIVIMLLFAYLAEKFQLAGIT 240
Query: 236 GAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVF 295
GAYL GL + + K++ M IGYS+FIP+F V +G+ D + L A FA +Y++
Sbjct: 241 GAYLAGLLVSMSEGSKKVTDKMMTIGYSLFIPIFLVSIGIETDIKVLATAGVFAIVYSLI 300
Query: 296 AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMT 355
A+I K+ GCG GA ++KF ++++GIGMIPR+ V L + + + G+ L + +T
Sbjct: 301 AIIGKIQGCGFGALVTKFKPAEALQVGIGMIPRMEVALIIANVGLKEGILTRGTLAIPVT 360
Query: 356 MVFLTTLITPIMLRKTY 372
MV +TTL+TP +L+ +
Sbjct: 361 MVVVTTLVTPFLLKLAF 377
>pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abyssi (strain
Orsay) >gi|5459083|emb|CAB50569.1| (AJ248288) Na+/H+
antiporter (napA-3) [Pyrococcus abyssi]
Length = 380
Score = 312 bits (790), Expect = 5e-84
Identities = 165/375 (44%), Positives = 245/375 (65%), Gaps = 7/375 (1%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLG 56
ME L LA++L +AK+ G++ R P LGQ++ GVI+G ++E + + LG
Sbjct: 1 MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
Query: 57 VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGT--ALLYGAI 114
V+MLLFLAGLE+D EEFK VG + +VA +GV FL G+L++ +G+ AL +G +
Sbjct: 61 VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSV-LHGYGSLKALFFGGV 119
Query: 115 MTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIV 174
+T TSV +T +LM++ KLRTK G TILAAA+VDDVLGI+ILT++++M G V + I
Sbjct: 120 LTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIE 179
Query: 175 EVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASI 234
+LLEVA F + + +G +++ V ++ LPE+ T+FAIV +++FAYLAE LA I
Sbjct: 180 IILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGI 239
Query: 235 LGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAV 294
GAYL GL + T ++I + IGYS+FIP+F V +G+ D R L A FA +Y++
Sbjct: 240 TGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSL 299
Query: 295 FAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAM 354
A++ K+IGCG GA +++F +I++GIGMIPR+ V L + + + G+ L V +
Sbjct: 300 IAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPV 359
Query: 355 TMVFLTTLITPIMLR 369
TMV +TTLITP +L+
Sbjct: 360 TMVVITTLITPFLLK 374
>gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus]
Length = 387
Score = 248 bits (626), Expect = 9e-65
Identities = 137/376 (36%), Positives = 223/376 (58%), Gaps = 8/376 (2%)
Query: 2 ETLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL----IERNEIIVEFANLGV 57
E +AL+L KL+G + R QP VLG++I G+++G IE +E++ + +N+GV
Sbjct: 4 EFFFQIALILLSTKLAGDLSVRLGQPSVLGKLIVGIVIGPAVLGWIENSELLTQLSNVGV 63
Query: 58 LMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMT 116
++L+F+AGLE+D EE S+ VA G++ F+ G++ + G A+ G ++
Sbjct: 64 ILLMFMAGLETDLEELNANRNSSLAVALGGIILPFVGGYVSGLVMGMEQGNAVFLGLLLC 123
Query: 117 PTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEV 176
TSVSI+V+ L +LGK++T+E T+L AAV DD+L +++L +S L V+ + V
Sbjct: 124 ATSVSISVQTLRDLGKMKTRESTTMLGAAVFDDILVVILLAFAMSFLGTDDVN---LTMV 180
Query: 177 LLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILG 236
+L+ F A + +G + + R LS + + ES S A++ FAY E L +A I+G
Sbjct: 181 ILKKVVFFASIILIGWKGVPAIMRWLSPLRVSESIVSAALIICFSFAYFGELLGIAGIIG 240
Query: 237 AYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFA 296
A+ G++I QT+YK +E + I Y++F+PVFFV +GM I + F V A
Sbjct: 241 AFAAGIAISQTNYKHEVEKKVEPIAYAMFVPVFFVSIGMNITFDGIGNQIWFILALTVIA 300
Query: 297 MISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTM 356
+++K+IGCG GA ++ FD ++S IG GM+ R V L + T +++G+ D T + +
Sbjct: 301 VLTKLIGCGFGARMTGFDAKSSAIIGAGMVSRGEVALIIAGTGLSSGLLAQDYFTAIVIV 360
Query: 357 VFLTTLITPIMLRKTY 372
V LTT+ITP ML+ T+
Sbjct: 361 VILTTMITPPMLKYTF 376
>gb|AAB40041.1| (U17283) putative spore germination apparatus protein [Bacillus
megaterium] >gi|1589214|prf||2210362A grmA gene
[Bacillus megaterium]
Length = 386
Score = 230 bits (580), Expect = 2e-59
Identities = 136/385 (35%), Positives = 226/385 (58%), Gaps = 21/385 (5%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL----IERNEIIVEFANLG 56
ME +L LAL+L K++G + R QP VLG+++ G+I+G I ++ + F+ +G
Sbjct: 1 MEFVLSLALILFATKIAGHLSVRLGQPSVLGKLLIGIILGPAVLGWIHNDQFVHYFSEIG 60
Query: 57 VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGT--ALLYGAI 114
VL+L+FLAGLE+D E+ KR + + VA +G++ F+ GF + F G +L G +
Sbjct: 61 VLLLMFLAGLETDLEQLKRNWKAAFAVAVLGIILPFIGGFGVG-ELFGLGATYSLFIGVL 119
Query: 115 MTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIV 174
+ TSVSITV+VL ++ +L ++EG+TIL AAVVDDVL +++L I+IS L G
Sbjct: 120 LCATSVSITVQVLKDMNRLNSREGSTILGAAVVDDVLVVVLLAIMISFLGTGE------- 172
Query: 175 EVLLEVAGFLAVFLYLGPV-----VMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHL 229
EV L + + ++G V V+ V L+ + + E S + + Y A+ +
Sbjct: 173 EVSLGLLVGKKLIFFIGAVLAGWLVVPKVLDWLTNLKVTEPVVSIGLAICFGYVYFADLM 232
Query: 230 NLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFA 289
+A I+GA+ G++I QTSY+ IE + I Y++F+PVFFV +G+ + + + F
Sbjct: 233 GMAGIIGAFAAGIAISQTSYRHTIESKVEPIAYAVFVPVFFVSIGLNVSFEGVGDQIGFI 292
Query: 290 FLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDV 349
L +V A+I+K++G LGA ++ F R+S+ IG GM+ R V L + +T + + +
Sbjct: 293 LLLSVIAVITKLVGGALGAKVTGFSTRSSLLIGSGMVSRGEVALIIAATGLQESLLLPEY 352
Query: 350 LTVAMTMVFLTTLITPIMLRKTYII 374
T A+ ++ +TTL+ P +++ YII
Sbjct: 353 FTSAVIVIIITTLVAPPLIK--YII 375
>sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A42111 Na+/H+-exchanging
protein NapA - Enterococcus hirae
>gi|148316|gb|AAA24781.1| (M81961) NaH-antiporter
protein [Enterococcus hirae]
Length = 383
Score = 217 bits (546), Expect = 2e-55
Identities = 126/378 (33%), Positives = 218/378 (57%), Gaps = 13/378 (3%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL----IERNEIIVEFANLG 56
ME + +L L+L + + RF P V+GQ++ GV++G + N ++ +F+ +G
Sbjct: 1 MEFIGILCLILVATTIGSHISRRFGIPAVIGQLLVGVLLGQAGLGWVHPNILVHDFSEIG 60
Query: 57 VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIM 115
V++L+FLAGLESD K+ +P + VA +G+LF FG+L F A+ +G I+
Sbjct: 61 VILLMFLAGLESDLSLLKKYFKPGMFVALLGILFPVFFGWLTGEAFQVANNEAIFFGIIL 120
Query: 116 TPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVE 175
TSVSI+V+VL EL + TKEG+TIL A+VVDD+L +L+L+ +S L S +
Sbjct: 121 AATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLVLSFSLSFLTGKSTSNLPLPL 180
Query: 176 VLLE-VAGFLAVFL---YLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNL 231
+LLE + FL +FL ++ P +M K+ + ++V + +YLA+ + L
Sbjct: 181 LLLEQLFYFLFIFLLVKWIAPFLMSLA----EKIYANSAIIIMSLVICLGMSYLADLIGL 236
Query: 232 ASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFL 291
+S++GA+ G+++ QT K + + +GY++FIPVFFV VG+ +D E F +
Sbjct: 237 SSVIGAFFAGIAVSQTKVKHEVYNNVEALGYAVFIPVFFVSVGLEVDFSKFSEQILFILI 296
Query: 292 YAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLT 351
+ A+++K+IG +GA S F +++ +G GMI R + L ++ + + + +
Sbjct: 297 LTLVAILTKLIGGYIGAKFSSFSSNSALMVGAGMISRGEMALIILQIGQQSNLIENHYYS 356
Query: 352 VAMTMVFLTTLITPIMLR 369
+ +V L+TLI+P++L+
Sbjct: 357 PLVIVVLLSTLISPLILK 374
>emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus lactis]
Length = 379
Score = 192 bits (483), Expect = 5e-48
Identities = 114/374 (30%), Positives = 204/374 (54%), Gaps = 8/374 (2%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLG 56
M +L L ++L + ++ R P V+GQ++ G+++ L+ ++ + +G
Sbjct: 1 MNDILQLTIVLIASLIATLASRRLKIPAVIGQMLVGILIAPSVLGLVHSGHVLEVMSEIG 60
Query: 57 VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIM 115
V++L+FLAGLESD K+ + S+LVA GV+ + L+A+ F + T+ YG +
Sbjct: 61 VILLMFLAGLESDLTVLKKNFKASMLVAIGGVIVPLIVFGLVAFSFGYGMSTSFFYGIVF 120
Query: 116 TPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVE 175
TSVSITV+VL E GKL T+ G+ IL AAVVDD+L +LIL+I S GS + + +
Sbjct: 121 AATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLILSIFTSFKNGGSGTH-LFFQ 179
Query: 176 VLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASIL 235
LLE+ F FL++ ++ ++ + K+ + T A++ + + LA+ + +++++
Sbjct: 180 FLLELLFF--AFLFVVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVI 237
Query: 236 GAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVF 295
G++ GL+I QT +IE + IGY IFIPVFFV + + + L L+ +
Sbjct: 238 GSFFAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTLL 297
Query: 296 AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMT 355
A+++K I +K S+ IG GMI R + L + + + + +V + +
Sbjct: 298 AILTKFIPAYFVGKSNKLSTGESMLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVI 357
Query: 356 MVFLTTLITPIMLR 369
++ L T++ P +++
Sbjct: 358 VIILATVLAPFLIK 371
>pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
>gi|3258023|dbj|BAA30706.1| (AP000006) 425aa long
hypothetical Na(+)/H(+) antiporter [Pyrococcus
horikoshii]
Length = 425
Score = 180 bits (451), Expect = 3e-44
Identities = 120/398 (30%), Positives = 209/398 (52%), Gaps = 40/398 (10%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIE--------------RNEII 49
L + + +AK+ + ERF P VLG+++ G+ +G L+ +E+I
Sbjct: 7 LFTIGTAIIIAKIGDSIVERFELPGVLGELLMGMALGNLVYFGLIKSEYLPITMGSSEVI 66
Query: 50 VEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFL-IAYPFFDFGTA 108
A LG+++LLFL L++D E+ KR G +++ +GV G+ + + + A
Sbjct: 67 DFLAKLGIILLLFLGALDTDIEKLKRTGVTAVVSTIMGVFVPLALGYYALRVMGYGYREA 126
Query: 109 LLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSV 168
G ++T TS+ +TV+++M+LG LR++ GA L+A+V+DD LGI ++I + GS
Sbjct: 127 FAGGVLLTATSIGLTVRIMMDLGALRSEVGAASLSASVIDDFLGI---ALIIFAVGSGS- 182
Query: 169 HYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEH 228
++E+ ++ F + LG ++++ + K+ + + I + +FA LAE
Sbjct: 183 ----LLELSAKIIVFFIITGVLGWYLVDHYIKFAEKLHVEKGVLGLVIGLMFIFAALAED 238
Query: 229 LNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFL--FEAK 286
A+I G+++ GL + + KRI + IGY IP+FFV G ++ EA
Sbjct: 239 WFAAAIEGSFMAGLILSKLPEGKRIMEEVRSIGYGFLIPLFFVHTGAMLNLTVFKNIEAF 298
Query: 287 TFAFLYAVFAMISKVIGCGLGAYL-----------SKFDWRTSIKIGIGMIPRLGVELAM 335
AF+ A++ KVIG G GA+L +K ++R S+++GIG IPR V L
Sbjct: 299 KLAFVLTTIAVVGKVIGRGFGAWLTAWGRGRGFLFTKQNFRMSLQMGIGSIPRTEVALVD 358
Query: 336 ISTAMAAGV--AGSDVLTVAMTMVFLT--TLITPIMLR 369
+ A+ G +G+ +A T++F+T LITP +L+
Sbjct: 359 LMVAIHGGAISSGNVPKFIAATLIFITVSVLITPPLLK 396
>pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abyssi (strain
Orsay) >gi|5458000|emb|CAB49490.1| (AJ248284) Na+/H+
antiporter (napA-2) [Pyrococcus abyssi]
Length = 426
Score = 177 bits (445), Expect = 2e-43
Identities = 118/398 (29%), Positives = 209/398 (51%), Gaps = 40/398 (10%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIE--------------RNEII 49
L + + L +AK+ + ERF P VLG++I G+++G L+ +E+I
Sbjct: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
Query: 50 VEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFG-FLIAYPFFDFGTA 108
A LG++ LLFL L++D E+ K+ G + + +GV + G F + Y + A
Sbjct: 68 DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127
Query: 109 LLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSV 168
G ++T TS+ +TV+V+M+LG LR++ GA L+A+V+DD LGI ++I + GS
Sbjct: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGI---ALIIFAVGSGS- 183
Query: 169 HYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEH 228
++ + +++ F + LG ++ R ++ + + A+ + LFA LAE
Sbjct: 184 ----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEG 239
Query: 229 LNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFL--FEAK 286
A+I G++++GL + + KRI + IGY + IP+FF+ G ++ +A
Sbjct: 240 WFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI 299
Query: 287 TFAFLYAVFAMISKVIGCGLGAYLSKF-----------DWRTSIKIGIGMIPRLGVELAM 335
A + + A+I KV G G GA+++ + +++ S+++GIG IPR V L
Sbjct: 300 KLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVD 359
Query: 336 ISTAMAAGVAGSDVLT--VAMTMVFLT--TLITPIMLR 369
+ A+ G D + +A T++F+T LITP +L+
Sbjct: 360 LMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLK 397
>pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus
>gi|2983453|gb|AAC07034.1| (AE000714) Na(+)/H(+)
antiporter [Aquifex aeolicus]
Length = 408
Score = 170 bits (427), Expect = 2e-41
Identities = 113/384 (29%), Positives = 194/384 (50%), Gaps = 20/384 (5%)
Query: 5 LMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVLML 60
L LA++L AKL G +F + P VLG++ AGVI+G LI +E I A LGV++L
Sbjct: 20 LHLAILLFSAKLFGSIFRKLGIPPVLGEVTAGVILGQSVLGLIPLSEAIKVLAELGVILL 79
Query: 61 LFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFF--DFGTALLYGAIMTPT 118
LF GLE+D RVG S LVA VG F GF+++Y FF D +L G +T T
Sbjct: 80 LFEVGLEADINMLMRVGLWSTLVAIVGAALPFAGGFIVSYYFFGLDLVASLFMGGALTAT 139
Query: 119 SVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLL 178
S+ ITV+VL +L K + + +L AAV+DD++G++IL + + +VH+D V +++
Sbjct: 140 SIGITVRVLTDLNKHKERFAQIVLGAAVLDDIMGVIILAALYEFSKTKAVHFDTTVNLII 199
Query: 179 EVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAY 238
+ F + ++ V+ + + K + + + ++L AY A SILG++
Sbjct: 200 HILMFFLIAPFVANVLAKLLSIAARKTQDMDLIPASIMALILLAAYSAHKFGSPSILGSF 259
Query: 239 LIGLSIGQ-------------TSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEA 285
GL++ + ++E + + + + P+FFV VG+ ++ + + +
Sbjct: 260 TAGLALSRRFVIPFAAMLRLDEKLLHKVEESITPLVW-VMAPIFFVSVGLALNLKAIDFS 318
Query: 286 KTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVA 345
+ ++ ++ +IG L +++ + IG M+PR V L +
Sbjct: 319 SPEFWTFSSALIVVAIIGKVLAGFVAPGSLKEKASIGFSMLPRGEVGLIFAEFGRSFKAI 378
Query: 346 GSDVLTVAMTMVFLTTLITPIMLR 369
V + +V +TTLI PI+L+
Sbjct: 379 NEVEYAVIVFVVAVTTLIAPIVLK 402
>pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp. (strain PCC
6803) >gi|1001188|dbj|BAA10332.1| (D64001)
NaH-antiporter protein [Synechocystis sp.]
Length = 461
Score = 169 bits (424), Expect = 4e-41
Identities = 120/413 (29%), Positives = 200/413 (48%), Gaps = 45/413 (10%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG-------------------LLIE 44
LL L ++ +KL G V R N P VLG+++ GV++G L+I+
Sbjct: 33 LLSLVVIYFASKLGGEVCLRLNLPPVLGELVGGVLVGVSALKLLLFPEGGLAPEDSLVIQ 92
Query: 45 -------------------RNEIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVAS 85
++E+I + LGV++LLF GLES+ +E RVG + +VA
Sbjct: 93 LLMGSADLSPEAAQSVFSAQSEVISVISELGVIILLFEIGLESNLKELIRVGPQAAIVAV 152
Query: 86 VGVLFAFLFGFLIAYPFFDFGT--ALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILA 143
VGV+ F G + F A+ GA +T TS+ IT KVL E+ +L + EG I+
Sbjct: 153 VGVVTPFSLGTIGLMTIFGVAAIPAIFAGAALTATSIGITAKVLAEINRLSSNEGQIIIG 212
Query: 144 AAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLS 203
AAV+DD+LGI++L +V S+++ G + I+ ++L GF+ + +G ++ ++
Sbjct: 213 AAVLDDILGIIVLAVVGSLVKTGEIQISNIIYLILSATGFVVGSILIGRLLSPFYVSLVN 272
Query: 204 KVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYS 263
++ +I + +Y+A+ + L +ILG++ GL + +T ++ +E + +
Sbjct: 273 RMKTRGQLLLVSICVAFVLSYIAQIVQLEAILGSFAAGLILAETEKREDLEEQILPLA-D 331
Query: 264 IFIPVFFVEVGMRIDPRFL---FEAKTFAFLYAVFAMISKVIG-CGLGAYLSKFDWRTSI 319
F+PVFFV VG + D L A + A F ++ ++G G L +
Sbjct: 332 FFVPVFFVCVGAKTDVSVLNPAVPANREGLIIAAFLILVAIVGKVVTGFTLFGKSELNKL 391
Query: 320 KIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLTTLITPIMLRKTY 372
IG+GMIPR V L A+G + MV +TT + P LR +
Sbjct: 392 AIGVGMIPRGEVGLVFAGVGAASGALDPATDAAIIVMVIVTTFVAPPWLRAVF 444
>pir||C82955 probable sodium/proton antiporter PA5529 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951867|gb|AAG08914.1|AE004965_6 (AE004965) probable
sodium/proton antiporter [Pseudomonas aeruginosa]
Length = 585
Score = 161 bits (404), Expect = 1e-38
Identities = 107/371 (28%), Positives = 190/371 (50%), Gaps = 10/371 (2%)
Query: 7 LALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL------LIERNEIIVEFANLGVLML 60
LA+++ VA + +F R QP+VLG I+AG I+G LI + I A LGV+ L
Sbjct: 10 LAVIMLVAGVVTILFHRLRQPVVLGYIVAGFIIGPHTPPFGLIHDEDTIKTLAELGVIFL 69
Query: 61 LFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGT--ALLYGAIMTPT 118
+F GLE + +VG + + A + ++ GF I FF++ T +L GAI+ +
Sbjct: 70 MFCLGLEFSLRKLFQVGATAFIAAFLEIVLMIWIGFEIGR-FFEWSTMDSLFLGAILAIS 128
Query: 119 SVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLL 178
S +I VK L +L + I +V+D+LGI I+ ++ + GSV + +
Sbjct: 129 STTIIVKALGDLKMKNERFAQLIFGVLIVEDILGIGIIALLSGIAVSGSVETGEVFSTVG 188
Query: 179 EVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAY 238
+++ F+ V L +G +++ + ++K + E + F L L + +LGA+
Sbjct: 189 KLSLFMIVALVVGILLVPRLLAYVAKFESNEMLLVTVLGLCFGFCLLVVKLEYSMVLGAF 248
Query: 239 LIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMI 298
LIG + ++ +IE + + +F +FFV +G+ IDP+ L E L V ++
Sbjct: 249 LIGAIMAESRQLVQIERLIEPVR-DMFSAIFFVAIGLLIDPKILVEYAWPIALITVAVVL 307
Query: 299 SKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVF 358
K+ CG+GA+++ D RTS+++G+G+ + + M V + VA+ +
Sbjct: 308 GKMFSCGMGAFIAGNDGRTSLRVGMGLSQIGEFSFIIAALGMTLKVTSDFLYPVAVAVSA 367
Query: 359 LTTLITPIMLR 369
+TTL+TP ++R
Sbjct: 368 ITTLLTPYLIR 378
>pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abyssi (strain
Orsay) >gi|5458640|emb|CAB50128.1| (AJ248286) Na+/H+
antiporter (napA-4) [Pyrococcus abyssi]
Length = 390
Score = 152 bits (380), Expect = 6e-36
Identities = 100/386 (25%), Positives = 190/386 (48%), Gaps = 20/386 (5%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERNEIIVEFANLG 56
M + L+++L VAK W+ ++ ++ I+ G+I+G +++ +E + G
Sbjct: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
Query: 57 VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFG--TALLYGAI 114
++M++ GL S+F R + +VA++GV F+F+ GF Y F + AL G
Sbjct: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVY-FIERNMIAALFVGIT 119
Query: 115 MTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIV 174
+ T++ +T VL+ +++ + + ++ AA DD++ + ++ ++ + +GS +V
Sbjct: 120 LGNTAIEVTSGVLVR-ERVKKEISSVLMGAAFADDIIAVYLIGLLTG-ITQGSFSLYPMV 177
Query: 175 EVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASI 234
+ +++ F+ L + V + R + V +F I+ + A+LAE + L I
Sbjct: 178 VLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQI 237
Query: 235 LGAYLIGLSIGQTSYKK-----------RIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLF 283
+GAYL GL+I + +K + + V+ FIP+FF+ VG+ P
Sbjct: 238 IGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVRE 297
Query: 284 EAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAG 343
+ L + A++ K+IGCGLG L R +I +G+GM R +ELA++ + G
Sbjct: 298 ISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKG 357
Query: 344 VAGSDVLTVAMTMVFLTTLITPIMLR 369
+ + + + LT L TPI R
Sbjct: 358 LINESLFATIVIVSMLTALSTPIFFR 383
>pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii
>gi|1591911|gb|AAB99281.1| (U67568) NA(+)/H(+)
antiporter (napA) [Methanococcus jannaschii]
Length = 388
Score = 145 bits (361), Expect = 1e-33
Identities = 96/376 (25%), Positives = 191/376 (50%), Gaps = 17/376 (4%)
Query: 9 LMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVLMLLFLA 64
++L++ + + ++FN P + +IAG+I+G +++ +E + A+ G +ML+FLA
Sbjct: 10 IILSIIFIVPNLLKKFNIPAITSIMIAGIIIGPYGLNILQVDETLKILADFGAIMLMFLA 69
Query: 65 GLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIA-YPFFDFGTALLYGAIMTPTSVSIT 123
GLE D E K+ + S++++ +L + G+LI Y F +LLY I SV+I
Sbjct: 70 GLEVDNETLKQEFKNSLILSLFSLLIPGVGGYLIGQYLGLGFIGSLLYAVIFASHSVAIV 129
Query: 124 VKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEVAGF 183
+L EL ++T+ G IL+A ++ D+ +L+L++VI + + + + LLE +
Sbjct: 130 YAILEELKMVKTRLGTIILSATIIVDLFTLLLLSVVIKL----GIGGENVGTFLLETVLY 185
Query: 184 LAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLS 243
+ V L P + +N+ K+ I+F+ + + E + + I+GA++ G++
Sbjct: 186 IGVLLLAIPSLSKNILGVFEKLHAQRIHYVLFIIFIAII--VGEVIGIHPIVGAFICGVA 243
Query: 244 IGQTSYKKR----IEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLY--AVFAM 297
+ + K+ + +N IGY FIP+FF+ +GM + R +F L + A+
Sbjct: 244 VSEALTKEEHDELLNKNLNAIGYGFFIPIFFLVLGMETNIRVIFNLSNLELLLITLISAV 303
Query: 298 ISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMV 357
K I + + FD + G+ +P++ L S G+ G+++ + +
Sbjct: 304 ALKFISGFIALRILGFDRIKNTIGGLLTVPKISASLVAASIGRELGLIGNEIFVTIVALS 363
Query: 358 FLTTLITPIMLRKTYI 373
+T ITPI+++ ++
Sbjct: 364 VITATITPIVVKHIFV 379
>pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
>gi|3257347|dbj|BAA30030.1| (AP000004) 390aa long
hypothetical Na(+)/H(+) antiporter [Pyrococcus
horikoshii]
Length = 390
Score = 144 bits (360), Expect = 1e-33
Identities = 101/389 (25%), Positives = 190/389 (47%), Gaps = 22/389 (5%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG-----LLIERNEIIVEFANL 55
M + L+++L VAK W+ ++ ++ I+ G+I+G +++ +E+ V
Sbjct: 1 MSYIFDLSILLVVAKSLEWLLKKKGIHPIIAHILTGIILGPFGLSIVLPTSELKV-LGEF 59
Query: 56 GVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFG--TALLYGA 113
G++M++ GL S+F R + +VA GV F+F+ GFL Y F + AL G
Sbjct: 60 GLIMMMLYMGLTSNFSAISRNKVKASVVAMFGVAFSFILGFLTVY-FLEKSLIAALFVGI 118
Query: 114 IMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVI 173
+ T++ +T VL+ +++ + ++ AA DD++ + ++ I+ + +G + +
Sbjct: 119 TLGNTAIEVTSGVLVR-ERVKKDISSVLMGAAFADDIIAVYLIGILTG-ITQGGISGLSL 176
Query: 174 VEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLAS 233
V + +++ F+ L L V + R + + +F IV A++A+ + L
Sbjct: 177 VFLTIKIVIFILGVLMLSEFVFKRSTRFYNIIRDLHIFFTFTIVLTFTLAFIAQDIGLNQ 236
Query: 234 ILGAYLIGLSIGQTSYKK-----------RIEGPMNVIGYSIFIPVFFVEVGMRIDPRFL 282
I+GAYL GL+I + +K + + ++ FIP+FFV VG+ +P
Sbjct: 237 IIGAYLAGLTISRLRERKDPMVITRIKLNELIEELEIVLVEFFIPLFFVYVGLMFNPNVR 296
Query: 283 FEAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAA 342
+ L A++ K+IGCGLG + R +I +GIGM R +ELA++ +
Sbjct: 297 DISILLILLLYASAVLGKLIGCGLGMKIFGSSIRDAIIVGIGMGGRGSLELAILKLGLEK 356
Query: 343 GVAGSDVLTVAMTMVFLTTLITPIMLRKT 371
G+ + + + LT L TP++ R T
Sbjct: 357 GLIDEGIFATVVIVSMLTALSTPVLFRYT 385
>pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spirochete
>gi|2688368|gb|AAC66821.1| (AE001150) Na+/H+ antiporter
(napA) [Borrelia burgdorferi]
Length = 701
Score = 138 bits (344), Expect = 1e-31
Identities = 110/399 (27%), Positives = 192/399 (47%), Gaps = 35/399 (8%)
Query: 1 METLLMLALMLAVAKLS-GWVFERFNQPIVLGQIIAGVIMG----------LLIER---- 45
M +M ++ ++ +S G + + P V+GQI AG+I+ LL
Sbjct: 31 MSAFVMSLAIIVISSISIGNLVAKIGIPKVIGQITAGIILSPNAFGKIQIPLLFPLGITQ 90
Query: 46 -------NEIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLI 98
NE I + + ++LLF AGLE+D + F + ++ V+ F L+
Sbjct: 91 IGENYLINEKIFAISTIASIILLFTAGLETDLKLFIKFLPRGGIIGITEVVGTFTSFVLM 150
Query: 99 AYPFFDFG----TALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGIL 154
A F+ T+L G I TPTS I +L K+ T EG TI++ +++DDVL +L
Sbjct: 151 ASIIFNVPLISPTSLFIGIIGTPTSAGIAASILSAKKKMSTSEGVTIISTSIIDDVLSML 210
Query: 155 ILTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLG---PVVMENVFRRLSKVDLPEST 211
+LT VI++ R S+ I + + + ++L L + E + R L K++
Sbjct: 211 MLTSVITISR--SISDLDIASSIKAIVQNIVIWLCLTFSLIYISETLSRLLKKLNSVTLA 268
Query: 212 TSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFV 271
T + + A + ++L ++ ++GAY+ GL++ +T I+ + + FIP+FF
Sbjct: 269 TVITLSLALTIASIFQNLGMSFVVGAYVFGLAMSKTDIVYVIQDKLTIF-ERFFIPIFFT 327
Query: 272 EVGMRIDPRFLF--EAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRL 329
+G+ D + E + A+I+K I C + A F+ ++KI GM+PR
Sbjct: 328 SIGLMSDINEILSKEVLILGLAISAIAIITKSIFCFIPALFLGFNKLGALKIATGMVPRG 387
Query: 330 GVELAMISTAMAAGVAGSDVLTVAMTMVFLTTLI-TPIM 367
V L M + A+++G + + + MVFL T+I TPI+
Sbjct: 388 EVSLIMANVALSSGFISQKIFGIIIIMVFLPTIIATPII 426
>dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans]
Length = 686
Score = 135 bits (337), Expect = 7e-31
Identities = 98/381 (25%), Positives = 186/381 (48%), Gaps = 19/381 (4%)
Query: 2 ETLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERNEIIVEFANLGV 57
+ +L+ A+ + V ++ + R P ++G I+AGV++G L++R+ IV +G+
Sbjct: 8 DPVLIFAIAMVVFFVAPLLMSRLRIPGIIGLILAGVVIGPNGFALLDRDPTIVLLGTVGL 67
Query: 58 LMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMT 116
L ++F+AGLE D E FK+ S+L ++ FLFG + + F A+L +I+
Sbjct: 68 LYIIFIAGLEIDLEGFKKYRNRSVLFGTLSFTIPFLFGLVFTFILGFSTPAAILLASILG 127
Query: 117 PTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEV 176
++ + + LG + + T + ++ D L +L+L IV + +G ++ +
Sbjct: 128 SHTL-LAYPIASRLGISKDRGVTTAVGGTIMTDTLALLVLAIVAGSM-QGELNSTFWFTI 185
Query: 177 LLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLF--AYLAEHLNLASI 234
+ + ++A+ L L P++ ++ FR +S E F V +LF AY A L I
Sbjct: 186 AVSLVLYVAITLILIPILAKSFFRTMSS----EGALEFIFVMSILFVTAYGATLAGLEPI 241
Query: 235 LGAYLIGLSIGQTSYK-KRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLF---EAKTFAF 290
+GA+L GL++ + + + + +G ++FIP F + VGM +D R L A A
Sbjct: 242 IGAFLAGLALNRFILEHSPLMNRIKFVGNALFIPFFLLSVGMLMDIRVLLGDPSAWLLAA 301
Query: 291 LYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGM-IPRLGVELAMISTAMAAGVAGSDV 349
L +F + K + + L + IK+ G+ +P+ LA G+ S V
Sbjct: 302 LVVIFVQLGKFLAAFISGKLYNYS-MDQIKLMFGLSVPQAAATLAATLVGFDLGLFDSAV 360
Query: 350 LTVAMTMVFLTTLITPIMLRK 370
+ + M+ +T ++ P ++ K
Sbjct: 361 VNAVIVMILVTCMVGPYVVEK 381
>gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40309|YJJ4_YEAST
HYPOTHETICAL 97.1 KD PROTEIN IN BCK1-TOK1 INTERGENIC
REGION >gi|630170|pir||S46584 probable membrane protein
YJL094c - yeast (Saccharomyces cerevisiae)
>gi|521094|emb|CAA54359.1| (X77087) 12 transmembrane
domains; J0909 ORF [Saccharomyces cerevisiae]
>gi|1008268|emb|CAA89387.1| (Z49369) ORF YJL094c
[Saccharomyces cerevisiae]
Length = 873
Score = 129 bits (321), Expect = 5e-29
Identities = 98/403 (24%), Positives = 192/403 (47%), Gaps = 35/403 (8%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLI------ERNEIIVE------ 51
L L+L V L F QP V+ ++I+GVI+G I N I
Sbjct: 27 LFQACLILLVCNLIHIPFSMMRQPKVISEVISGVILGPTIFGQIPNYTNTIFPTSSIPGL 86
Query: 52 --FANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFF------ 103
ANLG+++ +F GLE D K+ + ++++ V + F FG L+A P F
Sbjct: 87 NLVANLGIILFMFFLGLEVDIAFIKKHLKKALVIGIVTLAVPFGFGCLLAIPLFHTYANK 146
Query: 104 -------DFGTALLYGAI-MTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILI 155
F +++ A+ ++ T+ + ++L EL ++ + G +LAA +++D++G ++
Sbjct: 147 TEGERHIKFSVFMVFIAVSISVTAFPVLCRILNELRLIKDRAGIVVLAAGIINDIMGWIL 206
Query: 156 LTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVD--LPESTTS 213
L + I + + + +L+ A FL F L ++ V R ++D P +
Sbjct: 207 LALSIILSSAEGSPVNTVYILLITFAWFLIYFFPL-KYLLRWVLIRTHELDRSKPSPLAT 265
Query: 214 FAIVFLV-LFAYLAEHLNLASILGAYLIGLSIGQTS-YKKRIEGPMNVIGYSIFIPVFFV 271
I+F++ + AY + + + I GA++ GL + + Y ++ M I +FIP++F
Sbjct: 266 MCILFIMFISAYFTDIIGVHPIFGAFIAGLVVPRDDHYVVKLTERMEDIPNIVFIPIYFA 325
Query: 272 EVGMRIDPRFLFEAKTFAFLYAV--FAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRL 329
G+ +D L E + + +++A A+ +K+I L A L+ WR + G+ M +
Sbjct: 326 VAGLNVDLTLLNEGRDWGYVFATIGIAIFTKIISGTLTAKLTGLFWREATAAGVLMSCKG 385
Query: 330 GVELAMISTAMAAGVAGSDVLTVAMTMVFLTTLITPIMLRKTY 372
VE+ +++ + AG+ + + + M ++T +T + + Y
Sbjct: 386 IVEIVVLTVGLNAGIISRKIFGMFVLMALVSTFVTTPLTQLVY 428
>pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1001647|dbj|BAA10378.1| (D64002) Na(+)/H(+)
antiporter [Synechocystis sp.]
Length = 698
Score = 129 bits (320), Expect = 7e-29
Identities = 99/386 (25%), Positives = 185/386 (47%), Gaps = 26/386 (6%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG-----LLIERNEIIVEFANLGVL 58
L+ ++L V + +FER P ++G + AG+++G +L E +E I F ++G +
Sbjct: 13 LIDFTILLLVTLILPPIFERLKLPGLVGLLFAGIVLGKSGLGVLNEDSESIKLFTDIGKI 72
Query: 59 MLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMTP 117
L+F+AGLE D +F+R S+L S+ L G + F + F ++L G++
Sbjct: 73 YLMFVAGLEIDMVDFRRTRNRSLLYGSLTFAVPLLTGLAVGLTFGYSFNASVLLGSLFAS 132
Query: 118 TSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVL 177
++ + ++ LG +R + + A + D+ +L+L I IS + GS +V L
Sbjct: 133 HTL-LGYPIVQRLGIVRNQAVMVTIGATIFTDIAALLVLAICIS-IHSGSFSPAGLVVQL 190
Query: 178 LEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLF--AYLAEHLNLASIL 235
+ +A + A+ L FRR E + F V L +F + +E +N+ I+
Sbjct: 191 VAIAVYSALVLIGFDWAGREYFRRTGD----EQSNQFLFVLLAVFLASVGSELINVDKIV 246
Query: 236 GAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRID-PRFLFEAKTFAFLYAV 294
GA+L GL++ ++ + +G ++FIP FF+ +G+ +D P FL T F V
Sbjct: 247 GAFLAGLAVNDVLGNSPVKEKVEFLGTTLFIPFFFIGIGLLLDLPAFLVTLTTL-FPLVV 305
Query: 295 FAMISKVIGCGLGAYLSK----FDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSD-- 348
++ ++ G+ A L++ + W + + IP++ LA A A D
Sbjct: 306 AIVVGLILSKGVAAILAQWKLGYTWVEGLTMWSLSIPQVAATLAAAVAGYQAVNAAGDRL 365
Query: 349 ----VLTVAMTMVFLTTLITPIMLRK 370
VL + ++ +T+++ P+M K
Sbjct: 366 VSETVLNTIIVLMLITSIVGPLMTAK 391
>pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis
>gi|2633518|emb|CAB13021.1| (Z99110) similar to Na+/H+
antiporter [Bacillus subtilis]
Length = 614
Score = 128 bits (318), Expect = 1e-28
Identities = 110/392 (28%), Positives = 191/392 (48%), Gaps = 34/392 (8%)
Query: 7 LALMLAVAKLSGWVFERFNQ--PIVLGQIIAGVIMG-----LLIERNEIIVEFANLGVLM 59
L ++L VA L+ + RF P+V+ +II G+I+G L++E + + + LG +
Sbjct: 9 LVVVLIVAFLTPILLHRFKLSIPVVVAEIIMGLIIGKSGLNLVVEGDTWLQTLSMLGFIF 68
Query: 60 LLFLAGLESDFEEFKRVGRPSIL---------VASVGVLFA--FLFGFLIAYPFFDFG-- 106
L+FL+GLE DF F++ + L A+ V+F F+ L++Y F G
Sbjct: 69 LMFLSGLEIDFSSFEKGKKKQFLPNGKEAPNTFAAASVIFVGIFILSLLLSYGFVLAGFI 128
Query: 107 -TALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLRE 165
A L I++ S+ + V L E + + G IL AV+ D+ +++L + S+ E
Sbjct: 129 QNAFLMTLIISTISLGVVVPTLKEERIMNSNIGQIILLVAVIADLATMILLAVFSSLYGE 188
Query: 166 GSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVF-RRLSKVDLPESTTSFAIVFLVLFAY 224
S + +++ +L AG V + G V F + +SK + T + + +VL A
Sbjct: 189 DSGNMWLLM--ILFAAG--VVLYFFGRVFKHRSFVQSMSKGTIQIGTRAIFTLIIVLVA- 243
Query: 225 LAEHLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFE 284
L+E L +ILGA+L G+ + S K + ++ GY IP+FFV VG+++D LF+
Sbjct: 244 LSESLGAENILGAFLAGVLVSLLSPNKELVQQLDSFGYGFLIPIFFVMVGVKLDIWTLFQ 303
Query: 285 AKTFAF---LYAVFAMISKVIGCGLGAYLSK-FDWRTSIKIGIGMIPRLGVELAMISTAM 340
KT L + ++SK+I YL K +D RT G + L + +A +
Sbjct: 304 DKTILIMIPLLLLALLVSKIIPV---MYLKKWYDNRTIFASGFLLTSTLSLVIAAATIGQ 360
Query: 341 AAGVAGSDVLTVAMTMVFLTTLITPIMLRKTY 372
V +++ + + + ++ TPI +K Y
Sbjct: 361 QLHVISTNMSGALILVAVIASIFTPICFKKLY 392
>gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum]
Length = 713
Score = 116 bits (288), Expect = 4e-25
Identities = 100/390 (25%), Positives = 174/390 (43%), Gaps = 28/390 (7%)
Query: 3 TLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG-------------LLIERNEII 49
+L+ LAL+L A+ SG + R QP VLG++ GV++G L + +
Sbjct: 12 SLVTLALILVTARASGELARRLRQPEVLGELFGGVVLGPSVVGALAPGFHRALFQEPAVG 71
Query: 50 VEFAN---LGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFD-- 104
V + +G L+LL +AG+E D ++ RP L A + G + D
Sbjct: 72 VVLSGISWIGALLLLLMAGIEVDVGILRKEARPGALSALGAIAPPLAAGAAFSALVLDRP 131
Query: 105 FGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLR 164
+ L G +++ T+VS+ KVL+E +R LAA VV +V +++ + S
Sbjct: 132 LPSGLFLGIVLSVTAVSVIAKVLIERESMRRSYAQVTLAAGVVSEVAAWVLVAMTSSSY- 190
Query: 165 EGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVD-LPESTTSFAIVFLVLFA 223
G+ + L +GFL + +G + R ++ + + S +V L A
Sbjct: 191 -GASPALAVARSALLASGFLLFMVLVGRRLTHLAMRWVADATRVSKGQVSLVLVLTFLAA 249
Query: 224 YLAEHLNLASILGAYLIGLSIGQTSYKKR--IEGPMNVIGYSIFIPVFFVEVGMRIDPRF 281
L + L L +LGA+ +G+ + R ++G ++ +F PVFFV GMR+D
Sbjct: 250 ALTQRLGLHPLLGAFALGVLLNSAPRTNRPLLDGVQTLVA-GLFAPVFFVLAGMRVDVSQ 308
Query: 282 LFEAK---TFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMIST 338
L T A L A A +KV+ LGA L + + +G+ + G +L +
Sbjct: 309 LRTPAAWGTVALLLAT-ATAAKVVPAALGARLGGLRGSEAALVAVGLNMKGGTDLIVAIV 367
Query: 339 AMAAGVAGSDVLTVAMTMVFLTTLITPIML 368
+ G+ ++ T+ + +T +P +L
Sbjct: 368 GVELGLLSNEAYTMYAVVALVTVTASPALL 397
>pir||C70474 Na+/H+-exchanging protein - Aquifex aeolicus
>gi|2984253|gb|AAC07780.1| (AE000768) Na(+)/H(+)
antiporter [Aquifex aeolicus]
Length = 422
Score = 116 bits (287), Expect = 5e-25
Identities = 86/365 (23%), Positives = 171/365 (46%), Gaps = 19/365 (5%)
Query: 9 LMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIERNEI--IVEFANLGVLMLLFLAGL 66
L+L + G+ F++ N P ++ +I G + L+ +I F + G+++L F GL
Sbjct: 16 LVLLFMFIFGYTFQKVNIPSIIAFMIIGFLAQPLVPPEKIKDFEIFKHAGIILLFFFIGL 75
Query: 67 ESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMTPTSVSITVK 125
E FE + + + S+ +F F+ F+IAY F FD TAL+ A+ P+S SI K
Sbjct: 76 EYSFERLRTM-LGAWKTGSIDFVFNFIPPFIIAYAFGFDLITALILAAVFYPSSTSIIAK 134
Query: 126 VLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEVAGFLA 185
+LM+ ++ + E ++ + +D++ IL+LTI+I + GS+ + I L+++
Sbjct: 135 LLMDYKRIASPEAELLIGILIFEDLVAILLLTIIIPLKEAGSIEFTTIPVSLVKLGVAFL 194
Query: 186 VFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIG 245
+F + ++ + L +V + F + ++ + L ++ LGA+L+G+ +
Sbjct: 195 LFWLIYKYLIPKINAWLDRVSEEDIFIFFTLGLVLSIGTIFHSLGISEALGAFLLGVIVP 254
Query: 246 QTSYKKRIE---GPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISKVI 302
+T + IE + + +F F E + E L V +I K+I
Sbjct: 255 ETKVLENIEKQLSDLKELSMGLFFFFFAYETQLTKP-----ENLGLLILLIVLGIILKII 309
Query: 303 GCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLTTL 362
L Y+ ++ ++ + +PR E ++I T+ + + + +FLT +
Sbjct: 310 STYLAGYVFGLKKKSRLRASLSFVPR--GEFSVIMTSFEPALKSTSI-----PFIFLTAV 362
Query: 363 ITPIM 367
I I+
Sbjct: 363 IGSIL 367
>emb|CAB45049.1| (AL078635) putative integral membrane ion antiporter [Amycolatopsis
orientalis]
Length = 409
Score = 113 bits (281), Expect = 3e-24
Identities = 93/394 (23%), Positives = 182/394 (45%), Gaps = 35/394 (8%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLI------------ERNEIIVE 51
LL LA+++ +A+L G V R +QP V+G+++AG+++G + + +
Sbjct: 10 LLDLAVIVVLARLLGAVARRLDQPPVIGELLAGILLGPTLFGEGFAAALFPTDVRPFLAA 69
Query: 52 FANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-------FD 104
AN+GV M +F+ GLE + + G+ ++ V+ ++ F G +A+
Sbjct: 70 LANVGVAMFMFMVGLELEQTLLRGRGKLALTVSVSSIVLPFTLGVGLAFYLAMNRPVEHR 129
Query: 105 FGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLG--ILILTIVISM 162
G L GA M+ T+ + ++L + G LRT G L A + DVL +L + +++S
Sbjct: 130 LGFLLFIGAAMSVTAFPVLARILQDRGMLRTMLGGLALTCAAIGDVLAWCLLAVVVIVSG 189
Query: 163 LREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLF 222
G+ + +++ + ++A+ L++ ++ +F LP + ++
Sbjct: 190 GASGTEQWLIVLGPI-----YVALMLWVVRPLLRKLFTAGVTGALPT-----VLAGALIS 239
Query: 223 AYLAEHLNLASILGAYLIGLSI---GQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDP 279
+ E + L I GA+L G+ + G + + RI + ++ +PVFF+ G++++
Sbjct: 240 GAVTELIGLHFIFGAFLFGVIVPREGTDTLRHRIIDRVEEFNSALLLPVFFIVSGLKVNL 299
Query: 280 RFLFEAKTFAF-LYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMIST 338
L F L + A+ K G +GA L R S + M R EL +++
Sbjct: 300 STLSATGLVEFGLVLLVAIAGKFGGAFVGARLHGLPARKSAALATLMNTRGLTELIILTV 359
Query: 339 AMAAGVAGSDVLTVAMTMVFLTTLITPIMLRKTY 372
+ GV + ++ + M +TT + +LR Y
Sbjct: 360 GLQLGVLDQSLYSIMVAMAVITTAMAGPLLRLIY 393
>pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana
>gi|7629992|emb|CAB88334.1| (AL132960) putative protein
[Arabidopsis thaliana]
Length = 842
Score = 113 bits (279), Expect = 5e-24
Identities = 94/397 (23%), Positives = 187/397 (46%), Gaps = 36/397 (9%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG-LLIERN-------------EII 49
++ AL++AV++ +F+ QP V+ +I+ G+++G + RN I+
Sbjct: 30 IVQTALIIAVSRFLAVLFKPLRQPKVIAEIVGGILLGPSALGRNMAYMDRIFPKWSMPIL 89
Query: 50 VEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFD----- 104
A++G+L LFL GLE D +R G+ + +A G+ F+ G +A+ +
Sbjct: 90 ESVASIGLLFFLFLVGLELDLSSIRRSGKRAFGIAVAGITLPFIAGVGVAFVIRNTLYTA 149
Query: 105 -----FGTALLY-GAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTI 158
+ L++ G ++ T+ + ++L EL L T+ G T +AAA +DV ++L +
Sbjct: 150 ADKPGYAEFLVFMGVALSITAFPVLARILAELKLLTTQIGETAMAAAAFNDVAAWILLAL 209
Query: 159 VISMLREGSVHYD------VIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVD--LPES 210
+++ G V + VLL AGF+ L + M+ V +R S + + ES
Sbjct: 210 AVALAGNGGEGGGEKKSPLVSLWVLLSGAGFVVFMLVVIRPGMKWVAKRGSPENDVVRES 269
Query: 211 TTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQT-SYKKRIEGPMNVIGYSIFIPVF 269
+ +++ + + + + SI GA++ GL+I + + +R+ + + +P++
Sbjct: 270 YVCLTLAGVMVSGFATDLIGIHSIFGAFVFGLTIPKDGEFGQRLIERIEDFVSGLLLPLY 329
Query: 270 FVEVGMRIDPRFLFEAKTFAF--LYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIP 327
F G++ D + A+++ L V A K++G + A + K R ++ +G M
Sbjct: 330 FATSGLKTDVAKIRGAESWGMLGLVVVTACAGKIVGTFVVAVMVKVPAREALTLGFLMNT 389
Query: 328 RLGVELAMISTAMAAGVAGSDVLTVAMTMVFLTTLIT 364
+ VEL +++ V + + + M TT IT
Sbjct: 390 KGLVELIVLNIGKEKKVLNDETFAILVLMALFTTFIT 426
>pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp. (strain PCC
6803) >gi|1652066|dbj|BAA16991.1| (D90902) Na/H
antiporter [Synechocystis sp.]
Length = 410
Score = 111 bits (275), Expect = 1e-23
Identities = 98/407 (24%), Positives = 195/407 (47%), Gaps = 46/407 (11%)
Query: 4 LLMLA---LMLAVAKLSGWVFERFNQPIVLGQIIAGV-----IMGLL---IERN------ 46
LL+LA +++ +A+L G +F RF QP V+G+IIAG+ ++GLL +E++
Sbjct: 7 LLILANIIVIIGLARLIGLLFARFQQPPVIGEIIAGIMLGPSLLGLLSPALEKSFFPATT 66
Query: 47 -EIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAY----- 100
+ + +G++ +FL GLE + + ++ + +IL ++V + F F+ G ++++
Sbjct: 67 QPFLYLLSEIGLIFYMFLVGLELNPQYLRQKLKVAILTSNVSIFFPFVLGIVLSFFVLYS 126
Query: 101 -------PFFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGI 153
F F AL GA M+ T+ + ++L + G +T G L A VDD+
Sbjct: 127 LNQPNKTSFIPF--ALFIGAAMSITAFPVLARILKDTGLDKTPLGTLGLTCASVDDISAW 184
Query: 154 LILTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVD-LPESTT 212
+L I I++ R ++ LL + + + LG + + R + + L +
Sbjct: 185 CLLAIAIAVTRTDNIF--GAFPTLLGIIVYTVFMVTLGRKFFKYILRNYGQKNYLSQGLL 242
Query: 213 SFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQ-TSYKKRIEGPMNVIGYSIFIPVFFV 271
+F + ++L A L E + + I G +++G + + T+ + + +P+FF
Sbjct: 243 TFIYIMVILSAMLTEWIGIDVIFGGFILGAILPKNTNLSTELATKTEDFVSTFLLPIFFA 302
Query: 272 EVGMRIDPRFLFEAKTFAFLYAVFAMI--SKVIGCGLGAYLSK----FDWRTSIKIGIGM 325
G+ D L + +L+AV A++ + + G G Y++ + + + +G M
Sbjct: 303 YSGLSTDLGLLNK----PYLWAVCALVVAAAIAGKYCGVYVTTRALGVEKQEAKALGWLM 358
Query: 326 IPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLTTLITPIMLRKTY 372
R EL +++ + GV + T+ + M +TT+IT ++ K Y
Sbjct: 359 NTRGLTELIILNVGLKLGVISPVIFTMFVIMAIITTIITSPLVVKIY 405
>gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter [Arabidopsis thaliana]
Length = 821
Score = 109 bits (271), Expect = 4e-23
Identities = 87/392 (22%), Positives = 188/392 (47%), Gaps = 32/392 (8%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG-------------LLIERNEIIV 50
+L L L++ V + ++ + F QP V+ +I+ G+++G + +R+ +++
Sbjct: 41 VLQLTLVVVVTRFFVFILKPFRQPRVISEILGGIVLGPSVLGRSTKFAHTIFPQRSVMVL 100
Query: 51 E-FANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF------F 103
E AN+G+L LFL G+E D ++ G+ ++ +A G++ FL G ++
Sbjct: 101 ETMANVGLLYFLFLVGVEMDIMVVRKTGKRALTIAIGGMVLPFLIGAAFSFSMHRSEDHL 160
Query: 104 DFGTALLY-GAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISM 162
GT +L+ G ++ T+ + ++L EL + T+ G ++AA+V+D+ ++L + I++
Sbjct: 161 GQGTYILFLGVALSVTAFPVLARILAELKLINTEIGRISMSAALVNDMFAWILLALAIAL 220
Query: 163 LREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFL--- 219
+ + V++ A F+AV ++ VV + + K E+ + F I +
Sbjct: 221 AESDKTSF-ASLWVMISSAVFIAVCVF---VVRPGIAWIIRKTPEGENFSEFHICLILTG 276
Query: 220 -VLFAYLAEHLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRID 278
++ ++ + + S+ GA++ GL I + + + +P+FF G++ +
Sbjct: 277 VMISGFITDAIGTHSVFGAFVFGLVIPNGPLGLTLIEKLEDFVSGLLLPLFFAISGLKTN 336
Query: 279 PRFLFEAKTFAFLYAV--FAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMI 336
+ T+ L+ V A KVIG + A+ R I +G+ + + VE+ ++
Sbjct: 337 IAAIQGPATWLTLFLVIFLACAGKVIGTVIVAFFHGMPVREGITLGLLLNTKGLVEMIVL 396
Query: 337 STAMAAGVAGSDVL-TVAMTMVFLTTLITPIM 367
+ V + T+ + + +T +ITPI+
Sbjct: 397 NVGKDQKVLDDETFATMVLVALVMTGVITPIV 428
>gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana]
Length = 868
Score = 109 bits (271), Expect = 4e-23
Identities = 81/335 (24%), Positives = 162/335 (48%), Gaps = 15/335 (4%)
Query: 48 IIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGT 107
++ ANLG+L+ LFL GLE D +R G+ +I +A+ G+L F G + ++ F + +
Sbjct: 158 VLDTLANLGLLLFLFLVGLEIDLTSLRRTGKKAISIAAAGMLLPFGMGIVTSFAFPEASS 217
Query: 108 A----------LLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILT 157
+ + G ++ T+ + ++L EL L T G + AA ++DV ++L
Sbjct: 218 SGDNSKVLPFIIFMGVALSITAFGVLARILAELKLLTTDLGRISMNAAAINDVAAWVLLA 277
Query: 158 IVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVD-LPESTTSFAI 216
+ +S+ + + + +L +A +A FL + P + + + RR + + + E A+
Sbjct: 278 LAVSLSGDRNSPLVPLWVLLSGIAFVIACFLIV-PRIFKFISRRCPEGEPIGEMYVCVAL 336
Query: 217 VFLVLFAYLAEHLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMR 276
++L + + + + +I GA+++G+ + + I + + + +P++FV G++
Sbjct: 337 CAVLLAGFATDAIGIHAIFGAFVMGVLFPKGHFSDAIVEKIEDLVMGLLLPLYFVMSGLK 396
Query: 277 IDPRFLFEAKTFAFLYAVF--AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELA 334
D + K++ L V A K++G A L K R S+ +G+ M + VEL
Sbjct: 397 TDITTIQGVKSWGRLALVIVTACFGKIVGTVSVALLCKVRLRESVVLGVLMNTKGLVELI 456
Query: 335 MISTAMAAGVAGSDVLTVAMTMVFLTTLI-TPIML 368
+++ V + + M TT I TPI+L
Sbjct: 457 VLNIGKDRKVLSDQTFAIMVLMAIFTTFITTPIVL 491
>pir||T50062 Probable K+/H+-antiporter [imported] - fission yeast
(Schizosaccharomyces pombe) >gi|7160220|emb|CAB76234.1|
(AL157994) Probable K+/H+-antiporter
[Schizosaccharomyces pombe]
Length = 898
Score = 109 bits (271), Expect = 4e-23
Identities = 89/392 (22%), Positives = 188/392 (47%), Gaps = 27/392 (6%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG-LLIERNEIIVEF---------- 52
++ +++A+ +L QP V+ +II G+++G ++ R +++
Sbjct: 34 IVQAIIIIALCRLIHIPLSFLQQPRVIAEIIGGIVLGPTVMGRIPKFLDYIFPTSSMGPL 93
Query: 53 ---ANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIA---YPF---- 102
+NLG+++ LF+ G+E D + ++LV ++ F G I+ Y F
Sbjct: 94 NLVSNLGLVLFLFVIGMEVDLRVLVLNYKVTLLVTVFSIVIPFGAGAGISAGLYKFTTRE 153
Query: 103 FDFGTALLY-GAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVIS 161
F+FG LL+ M+ T+ + ++L EL L + G +L+A + +DV+G ++L + ++
Sbjct: 154 FEFGKFLLFISTAMSITAFPVLARILSELHLLHKRVGVIVLSAGIGNDVIGWILLALSVT 213
Query: 162 MLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLP-ESTTSFAIVFLV 220
++ GS V + +LL + L +F+ + P+V + S D P ES + ++
Sbjct: 214 LVNSGSGVRAVYI-LLLALGWCLFLFIAIKPLVYLLAVKTRSLKDKPSESFICIVLSMVL 272
Query: 221 LFAYLAEHLNLASILGAYLIGLSIG-QTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDP 279
+ A+ + + + I G +L+G I + +I + + +F+P++F G++ +
Sbjct: 273 VSAFFTDIIGIHPIFGGFLVGTIIPHENDLTVKITEKIEDLVNCLFLPLYFASSGLKTNI 332
Query: 280 RFLFEAKTFAFLYAVF--AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMIS 337
L K + + A+ SK+ L A + K W S+ +G M + VEL +++
Sbjct: 333 STLNTGKIWGYTIGTICVAIASKMGSSMLAARILKMPWSDSLVVGSLMSCKGLVELIVLN 392
Query: 338 TAMAAGVAGSDVLTVAMTMVFLTTLITPIMLR 369
++ G+ + ++ + M +TT +T M +
Sbjct: 393 IGLSTGILNETIFSMFVFMAVITTFVTTPMTK 424
>pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thaliana
>gi|4454039|emb|CAA23036.1| (AL035394) putative
Na+/H+-exchanging protein [Arabidopsis thaliana]
>gi|7269218|emb|CAB79325.1| (AL161559) putative
Na+/H+-exchanging protein [Arabidopsis thaliana]
Length = 820
Score = 108 bits (268), Expect = 9e-23
Identities = 87/397 (21%), Positives = 185/397 (45%), Gaps = 38/397 (9%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLI--------------ERNEII 49
+L + ++L + +L ++ QP V+ +I+ G+++G + ++
Sbjct: 34 ILQICIVLLLTRLLAFLLRPLRQPRVIAEIVGGILLGPSALGKSTKFINTVFPPKSLTVL 93
Query: 50 VEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAY--------- 100
ANLG++ LFL GLE D + KR G+ ++ +A G+ F+ G ++
Sbjct: 94 DTLANLGLIFFLFLVGLELDPKSLKRTGKRALSIALAGITLPFVLGIGTSFALRSSIADG 153
Query: 101 ----PFFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILIL 156
PF F G ++ T+ + ++L E+ L T G L+AA V+DV ++L
Sbjct: 154 ASKAPFLVF-----MGVALSITAFPVLARILAEIKLLTTDIGKIALSAAAVNDVAAWILL 208
Query: 157 TIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAI 216
+ +++ EGS + V L GF+ +++ ++ + +R + +
Sbjct: 209 ALAVALSGEGSSPLTSLW-VFLSGCGFVLFCIFVVQPGIKLIAKRCPEGEPVNELYVCCT 267
Query: 217 VFLVLFA-YLAEHLNLASILGAYLIGLSIGQT-SYKKRIEGPMNVIGYSIFIPVFFVEVG 274
+ +VL A ++ + + + ++ GA++IG+ + ++ + + + +F+P++FV G
Sbjct: 268 LGIVLAASFVTDFIGIHALFGAFVIGVIFPKEGNFANALVEKVEDLVSGLFLPLYFVSSG 327
Query: 275 MRIDPRFLFEAKTFAFLYAVF--AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVE 332
++ + + A+++ L V A K+IG L + K S+ +G M + VE
Sbjct: 328 LKTNVATIQGAQSWGLLVLVIFNACFGKIIGTVLVSLYCKVPLDQSLALGFLMNTKGLVE 387
Query: 333 LAMISTAMAAGVAGSDVLTVAMTM-VFLTTLITPIML 368
L +++ GV + + + M +F T + TP++L
Sbjct: 388 LIVLNIGKDRGVLNDQIFAIMVLMAIFTTFMTTPLVL 424
>dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabidopsis thaliana]
Length = 810
Score = 108 bits (268), Expect = 9e-23
Identities = 91/396 (22%), Positives = 186/396 (45%), Gaps = 29/396 (7%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG-LLIERNEIIVE----------- 51
+L + +++ + ++ ++ QP V+ ++I G+++G L+ R++ ++
Sbjct: 35 ILQIVIVIVLTRVLAYLLRPLRQPRVIAEVIGGIMLGPSLLGRSKAFLDAVFPKKSLTVL 94
Query: 52 --FANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGF--------LIAYP 101
ANLG+L LFLAGLE D + +R G+ ++ +A G+ F G I+
Sbjct: 95 ETLANLGLLFFLFLAGLEIDTKALRRTGKKALGIALAGITLPFALGIGSSFVLKATISKG 154
Query: 102 FFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVIS 161
+ G ++ T+ + ++L EL L T+ G ++AA V+DV ++L + I+
Sbjct: 155 VNSTAFLVFMGVALSITAFPVLARILAELKLLTTEIGRLAMSAAAVNDVAAWILLALAIA 214
Query: 162 MLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVL 221
L + V + V L F+ ++ P + + RR + + E T A + +VL
Sbjct: 215 -LSGSNTSPLVSLWVFLSGCAFVIGASFIIPPIFRWISRRCHEGEPIEETYICATLAVVL 273
Query: 222 F-AYLAEHLNLASILGAYLIGLSIGQTS-YKKRIEGPMNVIGYSIFIPVFFVEVGMRIDP 279
++ + + + S+ GA+++G+ I + + + + + +F+P++FV G++ +
Sbjct: 274 VCGFITDAIGIHSMFGAFVVGVLIPKEGPFAGALVEKVEDLVSGLFLPLYFVASGLKTNV 333
Query: 280 RFLFEAKTFAFLYAV--FAMISKVIGCGLGAYLS-KFDWRTSIKIGIGMIPRLGVELAMI 336
+ A+++ L V A K++G LG L+ K R +I +G M + VEL ++
Sbjct: 334 ATIQGAQSWGLLVLVTATACFGKILGT-LGVSLAFKIPMREAITLGFLMNTKGLVELIVL 392
Query: 337 STAMAAGVAGSDVLTVAMTMVFLTTLITPIMLRKTY 372
+ V + + M TT IT ++ Y
Sbjct: 393 NIGKDRKVLNDQTFAIMVLMALFTTFITTPVVMAVY 428
>dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arabidopsis thaliana]
Length = 800
Score = 108 bits (266), Expect = 2e-22
Identities = 88/397 (22%), Positives = 183/397 (45%), Gaps = 38/397 (9%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG------------LLIERNEIIV- 50
+L + L++ +L + + QP V+ +II G+++G + + + V
Sbjct: 36 ILQIVLVVVFTRLLAYFLKPLKQPRVIAEIIGGILLGPSALGRSKAYLDTIFPKKSLTVL 95
Query: 51 -EFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAY--------- 100
AN+G+L LFL GLE DF K+ G+ S+L+A G+ F+ G ++
Sbjct: 96 DTLANIGLLFFLFLVGLELDFAAIKKTGKKSLLIAIAGISLPFIVGVGTSFVLSATISKG 155
Query: 101 ----PFFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILIL 156
PF F G ++ T+ + ++L EL L T G ++AA V+DV ++L
Sbjct: 156 VDQLPFIVF-----MGVALSITAFPVLARILAELKLLTTDIGRMAMSAAGVNDVAAWILL 210
Query: 157 TIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVD-LPESTTSFA 215
+ I++ +G+ V V VLL GF+ + ++ + RR + + + E
Sbjct: 211 ALAIALSGDGTSPL-VSVWVLLCGTGFVIFAVVAIKPLLAYMARRCPEGEPVKELYVCVT 269
Query: 216 IVFLVLFAYLAEHLNLASILGAYLIGLSIGQTS-YKKRIEGPMNVIGYSIFIPVFFVEVG 274
+ ++ +++ + + + ++ GA+++G+ + + + + + + + +P++F G
Sbjct: 270 LTVVLAASFVTDTIGIHALFGAFVVGIVAPKEGPFCRILTEKIEDLVSGLLLPLYFAASG 329
Query: 275 MRIDPRFLFEAKTFAFLYAVF--AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVE 332
++ D + A+++ L V K++G + L K +R ++ +G M + VE
Sbjct: 330 LKTDVTTIRGAQSWGLLVLVILTTCFGKIVGTVGSSMLCKVPFREAVTLGFLMNTKGLVE 389
Query: 333 LAMISTAMAAGVAGSDVLTVAMTMVFLTTLI-TPIML 368
L +++ V + + M TT I TPI++
Sbjct: 390 LIVLNIGKDRKVLNDQAFAILVLMALFTTFITTPIVM 426
>gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus]
>gi|7451786|pir||A69277 Na+/H+ antiporter (napA-1)
homolog - Archaeoglobus fulgidus
>gi|2650426|gb|AAB91016.1| (AE001091) Na+/H+ antiporter
(napA-1) [Archaeoglobus fulgidus]
Length = 377
Score = 107 bits (264), Expect = 3e-22
Identities = 91/379 (24%), Positives = 174/379 (45%), Gaps = 20/379 (5%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLG 56
+E +AL+ A +S + ++ P+V+ +I+ G+I G+ +I +E + + G
Sbjct: 4 VEQFATIALISLTAFISPLIADKLRVPVVVLEIVLGMIFGVSFLNVIYASEWLSFLSLFG 63
Query: 57 VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLYGAIMT 116
++ L+FLAGLE D + + G +VA FA +A G L Y I+T
Sbjct: 64 LIFLMFLAGLEIDADVVLKSGHLKRVVA----FFALSLALSVALTAL-MGLNLFYAIILT 118
Query: 117 PTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEV 176
+V + V VL E+G + G + A+V D + +L+I Y +
Sbjct: 119 NVAVGVVVSVLREIGLEKEDFGQLNIVTALVSDFSTMFLLSIYF------ITGYLQVAFA 172
Query: 177 LLEVAGFLAVFLYLGPVV--MENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASI 234
L + FLA + + V+ + R + E ++ ++LF L+ L + +I
Sbjct: 173 FLIILVFLAAYRFGKLVIWHFPDFISRWFSDEPSEIGVRGSLAIMILFVGLSSLLGVEAI 232
Query: 235 LGAYLIGLSIGQT-SYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYA 293
LGA+L G+ + T K++ + +G+ FIP+FF++ G ++ + F+
Sbjct: 233 LGAFLAGVLLSITFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELN--ITQAGEGIGFILL 290
Query: 294 VFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVA 353
+ A+ V G + S F R +I +G+ +L + +A ++ +++GV T
Sbjct: 291 LLAVSVAVKGIPSLIFASNFGLRRAISMGMLQSTKLSLTIAGVAIGVSSGVITEFESTAL 350
Query: 354 MTMVFLTTLITPIMLRKTY 372
+T ++ L++P + R Y
Sbjct: 351 VTFTIISCLLSPTLFRFLY 369
>gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]
Length = 391
Score = 102 bits (251), Expect = 9e-21
Identities = 86/375 (22%), Positives = 169/375 (44%), Gaps = 21/375 (5%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL--------------LIERNEII 49
L +++ + +A++ + +++ P ++G+++AG+I+G LI N I
Sbjct: 8 LFDVSIFILLAEILSSLVQKYGLPKLIGELLAGMIIGPYALGSLLNQLLGFPLIGINSYI 67
Query: 50 VEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTAL 109
A V++L+F +GLE K G L A+ G L F + F +AL
Sbjct: 68 EFLAEFSVILLIFASGLEHGIAPIKSSGILGFLGATFGALLPFFAAYYFYISSFGLDSAL 127
Query: 110 LYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVH 169
+ G M TS++ ++ E GKL+ K ++++A DDV+ +L+L++VI++L+ S
Sbjct: 128 ILGTAMGATSLAAVASIIEE-GKLKGKGINFMVSSAAADDVVDLLLLSVVIAILQGESTS 186
Query: 170 YDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHL 229
I ++ + V L + +++ + R+S + E F + L L L
Sbjct: 187 VTSISLKIIALVVIWVVILVVSIILIPKITDRISDKYIEE----FPLAVLFGLTLLMVSL 242
Query: 230 NLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFL-FEAKTF 288
+ I+ A++ G++ + +I+ + + S+F P+FFV +G ++ L
Sbjct: 243 GYSPIISAFVAGVAFANSVKNSKIKEISSTL-LSVFGPLFFVYIGAEVNFLTLNLNTVIL 301
Query: 289 AFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSD 348
+ A I K +G A + + + + +GM+PR L + S ++ +
Sbjct: 302 SLELTAIATIFKWLGIFPFALAYLRNAKAANTVALGMVPRGETGLVIASLGLSYNALNQE 361
Query: 349 VLTVAMTMVFLTTLI 363
+ M TTLI
Sbjct: 362 EFEGIVFMSIFTTLI 376
>pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis
>gi|2226151|emb|CAA74453.1| (Y14080) hypothetical
protein [Bacillus subtilis] >gi|2633321|emb|CAB12825.1|
(Z99109) similar to Na+/H+ antiporter [Bacillus
subtilis]
Length = 408
Score = 101 bits (249), Expect = 1e-20
Identities = 83/353 (23%), Positives = 165/353 (46%), Gaps = 14/353 (3%)
Query: 28 IVLGQIIA------GVIMGLLIERNEIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSI 81
IVLG ++ G+I I+ +EII F +GVL LLF GLE + + G+
Sbjct: 37 IVLGMLVGPHAPKMGIIDLTFIQSSEIIEFFGRMGVLFLLFYLGLEFSVGKLIKSGKSIA 96
Query: 82 LVASVGVLFAFLFGFLIAY-PFFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGAT 140
+ ++ +L F G L + F F L+ ++T +S +I KVL++L + E
Sbjct: 97 VGGTIYILINFSLGLLYGFITGFSFLEVLILAGVITISSSAIVAKVLVDLKRTANPETEL 156
Query: 141 ILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFR 200
IL + +D+ + L++V ++ + + +L G++ +F ++ + +
Sbjct: 157 ILGIIMFEDIFLAVYLSVVSGLILGDATSVGSALLSILIAFGYMLLF-FIAARKLPPLLN 215
Query: 201 RLSKVDLPESTTSFAIVFLVLF--AYLAEHLNLASILGAYLIGLSIGQTSYKKRIEGPMN 258
+L +D+ + ++F LF A +E +++A +GA L+GL +T + RIE +
Sbjct: 216 KL--LDIRSNEVFIIVIFAALFFIAGFSETIHVAEAIGALLLGLVFSETEHSDRIE-HLV 272
Query: 259 VIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTS 318
V F +FF G+ IDP L EA A + ++ I + + + S
Sbjct: 273 VPFRDFFGAMFFFSFGLSIDPFSLGEAVWLALGAVILTILGNFIAGMVAGRRAGLSHKAS 332
Query: 319 IKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLTTLITPIMLRKT 371
IG+ ++ R + + + +A G++ + + A V + ++ P++ +++
Sbjct: 333 SNIGLTIVSRGEFSIIVANLGIAGGLSAT-LKPFAALYVLILAILGPLVTKES 384
>dbj|BAA06982.1| (D32253) MagA [Magnetospirillum sp.]
Length = 434
Score = 100 bits (247), Expect = 3e-20
Identities = 84/373 (22%), Positives = 174/373 (46%), Gaps = 14/373 (3%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVLM 59
L A++ A L G + R QP V+G I+AGV++G L+ + + A GVLM
Sbjct: 8 LTYAAIVALAAVLCGGMMTRLKQPAVVGYILAGVVLGPSGFGLVSNRDAVATLAEFGVLM 67
Query: 60 LLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMTPT 118
LLF+ G++ D F V + +I + + + L+ + + G A++ G + +
Sbjct: 68 LLFVIGMKLDIIRFLEVWKTAIFTTVLQIAGSVGTALLLRHGLGWSLGLAVVLGCAVAVS 127
Query: 119 SVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLL 178
S ++ +KVL +L T G T L + D+ + ++ ++ S + + D + V+L
Sbjct: 128 STAVVIKVLESSDELDTPVGRTTLGILIAQDMAVVPMMLVLESFETKALLPAD-MARVVL 186
Query: 179 EVAGFLAVFLYLGPVVME-NVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGA 237
V + +F +L ++ + RLS+ + T + + A ++ L+L+ GA
Sbjct: 187 SVLFLVLLFWWLSKRRIDLPITARLSRDS--DLATLSTLAWCFGTAAISGVLDLSPAYGA 244
Query: 238 YLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAM 297
+L G+ +G ++ + + IG S+ + VFF+ +G+ +D +F++ K + + AM
Sbjct: 245 FLGGVVLGNSAQRDMLLKRAQPIG-SVLLMVFFLSIGLLLDFKFIW--KNLGTVLTLLAM 301
Query: 298 IS--KVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMT 355
++ K L++ DW ++ G+ + + T A + + + +
Sbjct: 302 VTLFKTALNVTALRLARQDWPSAFLAGVALAQIGEFSFLLAETGKAVKLISAQETKLVVA 361
Query: 356 MVFLTTLITPIML 368
+ L+ +++P L
Sbjct: 362 VTVLSLVLSPFWL 374
>pir||C71934 glutathione-regulated potassium-efflux system protein -
Helicobacter pylori (strain J99)
>gi|4154959|gb|AAD06004.1| (AE001476)
GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN
[Helicobacter pylori J99]
Length = 416
Score = 100 bits (246), Expect = 3e-20
Identities = 67/305 (21%), Positives = 152/305 (48%), Gaps = 18/305 (5%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIERNE--IIVEFANLGVLMLL 61
+++ L LAV G ++ + P+++G I G ++ + N+ ++ + G++ L+
Sbjct: 8 IVIAGLWLAVG--FGIFLKKLDMPVIIGYICTGTVLAAFFKINDFNLLSDIGEFGIVFLM 65
Query: 62 FLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAY------PFFDFGTALLYGAIM 115
F+ G+E +F++ K + + ++ + V+ L FL+ Y P F +L+ G +
Sbjct: 66 FMIGIEFNFDKLKSIKQEVLVFGLLQVVLCALIAFLLGYFVLGLSPIF----SLVLGMGL 121
Query: 116 TPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVE 175
+ +S +I +K + +L T G + + + D+ I +L +++++L H ++++
Sbjct: 122 SLSSTAIVLKFFEDSKQLSTPMGKSAVGILIFQDIAAIPML-LILTILGSKDSHVNLLIL 180
Query: 176 VLLEVAGFLAVFLYL-GPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASI 234
L AG + + L L G + + LPE +V + A L+ +
Sbjct: 181 KTLISAGIILILLLLPGKKGANLILEQAKDTRLPEIFIGTVLVIVCSAAGLSHFFGFSMS 240
Query: 235 LGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAV 294
LGA+++G++I ++ YK ++ + ++F+ +FF+ +GM+I+ F E K F ++ +
Sbjct: 241 LGAFIVGMAISKSRYKINVQEEFAQL-KNLFLALFFITIGMQINVSFFME-KFFVVIFLL 298
Query: 295 FAMIS 299
++S
Sbjct: 299 ILVMS 303
>pir||A81330 probable glutathione-regulated potassium-efflux system protein
Cj1231 [imported] - Campylobacter jejuni (strain NCTC
11168) >gi|6968664|emb|CAB73485.1| (AL139077) putative
glutathione-regulated potassium-efflux system protein
[Campylobacter jejuni]
Length = 541
Score = 100 bits (246), Expect = 3e-20
Identities = 79/376 (21%), Positives = 162/376 (43%), Gaps = 6/376 (1%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL--IERNEIIVEFANLGVLMLL 61
L + + +A+A + +F++F P ++G I AG I+ + + I A G++ L+
Sbjct: 5 LEIFLITVAIAIVLNVIFKKFEIPTIIGYIAAGEIISEIYHLSGKGEITHIAEFGIVFLM 64
Query: 62 FLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFG--TALLYGAIMTPTS 119
F GLE F+ + + L S+ +L L+A G +A + G + +S
Sbjct: 65 FTIGLEFSFKHLMAMKQEVFLNGSLQMLTCGFVFMLLAIGILGLGDKSATIVGFALALSS 124
Query: 120 VSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLE 179
++ +K+L + G + + G L + D+ I +L +V ++ L+
Sbjct: 125 TAVVLKILNDNGDINEQYGRKALGILLFQDIAVIPLLLLVDIFSSNNQNIEKLLFTSLIS 184
Query: 180 VAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYL 239
+ + ++G +++ +FR + E S + ++ ++LA + + LGA++
Sbjct: 185 ALILITLLFFIGKYLVDRIFRLIIHTSSQEIFISTVLFMVIGASFLANYFGFSYSLGAFI 244
Query: 240 IGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMIS 299
G I +T YK +IE + + + + +FF+ VGM+I + + F + +++
Sbjct: 245 AGALIAETKYKHKIEADL-IPFRDLLLGLFFITVGMQIQLDVVAQ-NWFLIIVLTLLVMA 302
Query: 300 KVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFL 359
G G R ++K + LA+ S A + + + + L
Sbjct: 303 LKFGIVFGFLFLYTKKRVALKTAFAIAQIGEFALAIFSLLQAKNMLDIKTSQILIVVSIL 362
Query: 360 TTLITPIMLRKTYIIT 375
T +ITP +L IT
Sbjct: 363 TMIITPFILNNIRKIT 378
>pir||G64578 glutathione-regulated potassium-efflux system protein -
Helicobacter pylori (strain 26695)
>gi|2313582|gb|AAD07539.1| (AE000562)
glutathione-regulated potassium-efflux system protein
(kefB) [Helicobacter pylori 26695]
Length = 416
Score = 95.2 bits (233), Expect = 1e-18
Identities = 82/398 (20%), Positives = 183/398 (45%), Gaps = 43/398 (10%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIERNE--IIVEFANLGVLMLL 61
+++ L LAV G ++ + P+++G I G ++ + N+ ++ + G++ L+
Sbjct: 8 IVIAGLWLAVG--FGIFLKKLDMPVIIGYICTGTVLAAFFKINDFDLLSDIGEFGIVFLM 65
Query: 62 FLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAY------PFFDFGTALLYGAIM 115
F+ G+E +F++ K + + ++ + V+ L FL+ Y P F +L+ G +
Sbjct: 66 FMIGIEFNFDKLKSIKQEVLVFGLLQVVLCALIAFLLGYFVLGLSPIF----SLVLGMGL 121
Query: 116 TPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVE 175
+ +S +I +K + +L T G + + + D+ I +L +++++L + ++++
Sbjct: 122 SLSSTAIVLKFFEDSKQLSTPMGKSAVGILIFQDIAAIPML-LILTILGSKDSNVNLLIL 180
Query: 176 VLLEVAGFLAVFLYL-GPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASI 234
AG + V L L G + + LPE +V + A L+ +
Sbjct: 181 KTFISAGIILVLLLLPGKKGANLILEQAKDTRLPEIFIGTILVIVCSAAGLSHFFGFSMS 240
Query: 235 LGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAV 294
LGA+++G++I ++ YK ++ + ++F+ +FF+ +GM+I+ F E K F ++ +
Sbjct: 241 LGAFIVGMAISKSRYKINVQEEFAQL-KNLFLALFFITIGMQINVSFFME-KFFVVIFLL 298
Query: 295 FAMISKVIGCGLGAYLSKF-DWRTSIKIGIGMI----------------------PRLGV 331
++ + A L F D +T+IK + + + G+
Sbjct: 299 ILVMGFKTAI-IYALLRFFRDAKTAIKTALSLAQIGEFSFVIFLNSGSHQLFNLQEKKGI 357
Query: 332 ELAMISTAMAAGVAGSDVLTVAMTMVFLTTLITPIMLR 369
L + +A +D+ + + MV + L TP +L+
Sbjct: 358 -LGFLHQKNILNIAQNDIHQLLILMVVFSMLATPFILK 394
>gb|AAF69026.1| (AF182516) unknown [Pseudomonas putida]
Length = 390
Score = 95.2 bits (233), Expect = 1e-18
Identities = 89/373 (23%), Positives = 176/373 (46%), Gaps = 16/373 (4%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVLM 59
+ +LA++L V + +R V G ++AG+++G L+ + + + +GV+M
Sbjct: 5 VFLLAVVLLVP-----LAQRLKMGAVPGYLLAGILIGPSVFGLLGNPDNVARLSEMGVVM 59
Query: 60 LLFLAGLESDFEEFKRVGRPSILVASVGV-LFAFLFGFLIAYPFFDFG--TALLYGAIMT 116
LLF+ GLE + + R V S+ V L A L G L+A+ FD A++ G +
Sbjct: 60 LLFVIGLELSPKRLWTMRRALFGVGSLQVGLTAVLLG-LLAFWLFDQSKPAAIVLGLGLA 118
Query: 117 PTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEV 176
+S + ++VL E L G +A + D+ I ++ +V + + S + +
Sbjct: 119 LSSTAFGLQVLAERKDLGKPHGRMAVAILLFQDIAAIPLIAVVPLLGGDVSTADEGAWPL 178
Query: 177 LLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILG 236
L V G + V + G ++ +F+ LPE +T+ A++ ++ A+L EH+ ++ LG
Sbjct: 179 LAVVVG-IGVLIVFGRYLLTPIFKWTVGSGLPELSTATALLVVLGTAWLMEHVGVSMALG 237
Query: 237 AYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAF-LYAVF 295
A+L G+ + ++ ++ +E + I +F+ +FFV VGM D R LF L +
Sbjct: 238 AFLAGVLMAESPFRHELETQIEPI-KGLFLGLFFVGVGMSADLRLLFGMPLMVLGLTLLL 296
Query: 296 AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMT 355
I + GLG + + ++ +G+ + + A+ V V + +
Sbjct: 297 VAIKLPLLYGLGRTMGGLNKSQALCLGVVLASGGEFXFVVFKLALEHQVLTQAVHDLLVL 356
Query: 356 MVFLTTLITPIML 368
+ L+ + P+++
Sbjct: 357 AITLSMAVVPLVM 369
>pir||B82056 glutathione-regulated potassium-efflux system protein KefB VC2606
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9657194|gb|AAF95747.1| (AE004327)
glutathione-regulated potassium-efflux system protein
KefB [Vibrio cholerae]
Length = 656
Score = 93.6 bits (229), Expect = 3e-18
Identities = 92/369 (24%), Positives = 176/369 (46%), Gaps = 18/369 (4%)
Query: 9 LMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVLMLLFLA 64
+ L+ A ++ + +R VLG ++AG+ +G LI + I+ FA GV++LLFL
Sbjct: 70 VFLSAAVIAVPLAQRAGLGSVLGYLLAGIAIGPWGLGLIRDVQAIMHFAEFGVVLLLFLI 129
Query: 65 GLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMTPTSVSIT 123
GLE + ++ + P + + V+ +AY + +AL+ G + +S +I
Sbjct: 130 GLELNPKKLWNLRGPILGLGGAQVVVTTAVLSSVAYLLGVSWQSALVIGMALALSSTAIA 189
Query: 124 VKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEVAGF 183
++V+ E G RT+ G + A + D+ I +L ++ + S + L + G
Sbjct: 190 LRVIEEHGLTRTEAGQSGFAVLLFQDIAVIPMLALLPILAGNSSGDW----LNALWMTGG 245
Query: 184 LAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLS 243
+A L G ++ +FR ++ + E T A++ +V A L + + L+ LG +L G+
Sbjct: 246 IAALLLGGHFLLNPLFRYIALSGVRELFTVAALLLVVGIALLMQKVGLSMALGTFLAGVI 305
Query: 244 IGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISKVIG 303
+ ++ ++ +E ++ + + +FF+ VGM +D L L + A++ VI
Sbjct: 306 LAESEFRHELEIAIDPF-KGLLLGLFFISVGMAVDVGLLLVKP----LQIMLAVLGLVIV 360
Query: 304 CGLGAYLSKFDWRTSIKIGIGMIPRL--GVELAMI--STAMAAGVAGSDVLTVAMTMVFL 359
GL YL T K M L G E A + + A A G+ + ++ + +V L
Sbjct: 361 KGLVLYLLARLSGTVAKARSKMAAILSQGGEFAFVIFTAASAEGLLTASQVSFLLVVVSL 420
Query: 360 TTLITPIML 368
+ + TP++L
Sbjct: 421 SMVTTPLLL 429
>pir||D71642 glutathione-regulated potassium-efflux system protein kefb (kefB)
RP810 - Rickettsia prowazekii
>gi|3861337|emb|CAA15236.1| (AJ235273)
GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN
KEFB (kefB) [Rickettsia prowazekii]
Length = 575
Score = 93.2 bits (228), Expect = 4e-18
Identities = 88/374 (23%), Positives = 173/374 (45%), Gaps = 14/374 (3%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG---LLIERNEIIVEFANLGVLML 60
L+ + ++L A + +RF VLG +IAG +G L I + LGV+ L
Sbjct: 6 LINVIILLGTAVFIVAILKRFRLSPVLGYLIAGAAIGDHGLKIVTYDQTKLLGELGVVFL 65
Query: 61 LFLAGLESDFEEFKRVGRPSILVASVGVL-FAFLFGFLIAYPFFDFGTALLYGAIMTPTS 119
LF GLE FE K + R + S+ VL A + + + A++ G + +S
Sbjct: 66 LFAIGLELSFERLKAMRRYVFGLGSLQVLTTAIVIAGAMVLIDGNSSAAIITGGGLALSS 125
Query: 120 VSITVKVLMELGKLRTKEGATILAAAVVDD--VLGILILTIVISMLREGSVHYDVIVEVL 177
++ ++V+ E T+ G LA ++ D V+ +L++ +++ + S+ + + L
Sbjct: 126 TALVMQVIDENRSQSTQIGRISLAILLLQDLAVVPLLVIVPLLASNNKASLAVALGIAFL 185
Query: 178 LEVAGFLAVFLYLGPVVMENVFRRLSKV--DLPESTTSFAIVFLVLFAYLAEHLNLASIL 235
V L +F+ +G V++ VF +S + E S ++ ++ A+ E L+ L
Sbjct: 186 KAVTALLTIFI-VGRVLLRPVFSFISSESNNTSELPISMTLLIVLSAAWATETFGLSLAL 244
Query: 236 GAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVF 295
GA++ G+ + +T ++ + E + S+F+ +FF+ VGM ID ++E + ++
Sbjct: 245 GAFVAGVLVAETEFRLQAEESIYPF-KSLFLGLFFMTVGMNIDALEMYEKISHILTLSIA 303
Query: 296 AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMI--STAMAAGVAGSDVLTVA 353
+ K + + A+ F + + G++ G E I S +GV +
Sbjct: 304 LICIKTL--IITAFCILFGFNKGVAFYSGLLLSQGGEFGFILFSLGKDSGVLEESTADIL 361
Query: 354 MTMVFLTTLITPIM 367
+ +V T +TP++
Sbjct: 362 LLVVTFTMALTPLL 375
>pir||C83496 glutathione-regulated potassium-efflux system protein KefB PA1207
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9947134|gb|AAG04596.1|AE004550_12 (AE004550)
glutathione-regulated potassium-efflux system protein
KefB [Pseudomonas aeruginosa]
Length = 613
Score = 93.2 bits (228), Expect = 4e-18
Identities = 85/359 (23%), Positives = 171/359 (46%), Gaps = 18/359 (5%)
Query: 22 ERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVLMLLFLAGLESDFEEFKRVG 77
+R VLG ++AGV++G L++ E + + + +GV++LLF+ GLE V
Sbjct: 26 KRLQLGAVLGYLLAGVLIGPSVLGLVDNPESVAQISEMGVVLLLFIIGLELSPRRLW-VM 84
Query: 78 RPSILVASVGVLFAFLFGFLI---AYPFFD--FGTALLYGAIMTPTSVSITVKVLMELGK 132
R S+ VG+L L G +I A FD +A++ G + +S + +++L E +
Sbjct: 85 RKSVF--GVGLLQVLLTGLVIGTVALVGFDQPVNSAVVLGLGLALSSTAFGLQILAERKE 142
Query: 133 LRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGP 192
L G A + D+ I ++ ++ + S + L+V G +A + G
Sbjct: 143 LTQPHGRLAFAILLFQDIAAIPLIAMIPLLSGAHSDAGGSELTQTLKVVGSIAAVVVGGR 202
Query: 193 VVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQTSYKKR 252
++ VFR +++ L + +T+ A++ ++ A L E ++ LGA+L GL + + Y+
Sbjct: 203 YLLRPVFRIVAQTKLQDMSTATALLVVMGTALLMELAGVSMALGAFLAGLLLADSEYRHE 262
Query: 253 IEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISKV-IGCGLGAYLS 311
+E + + + +FF+ VGM D L ++ V + K + +G
Sbjct: 263 LEAQIEPF-KGLLLGLFFISVGMSADISLLLKSPWMVLGLTVLLIALKAPVLYFVGRISG 321
Query: 312 KFDWRTSIKIGIGMIPRLGVELAMISTAMA--AGVAGSDVLTVAMTMVFLTTLITPIML 368
D +++++G+ + G E A + MA G+ +D+ + + + L+ +TP+++
Sbjct: 322 GLDKASALRLGV--VLAAGGEFAFVVFKMARDQGLFQNDLHNLLVLSITLSMALTPLLV 378
>sp|P44933|KEFX_HAEIN GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN (K(+)/H(+)
ANTIPORTER) >gi|1075164|pir||A64102
glutathione-regulated potassium efflux system protein
kefC homolog - Haemophilus influenzae (strain Rd KW20)
>gi|1573928|gb|AAC22568.1| (U32772)
glutathione-regulated potassium efflux system protein
(kefC) [Haemophilus influenzae Rd]
Length = 618
Score = 92.4 bits (226), Expect = 7e-18
Identities = 90/382 (23%), Positives = 175/382 (45%), Gaps = 28/382 (7%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLG 56
M+ +++LA + + L F+R VLG ++AG ++G +++ +V A LG
Sbjct: 10 MKVVILLASSVTIVPL----FKRLGLGSVLGYLVAGCLIGPSVFGIVQEPTAVVHLAELG 65
Query: 57 VLMLLFLAGLESDFEEFKRV-----GRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLY 111
V+M LF+ GLE E + GR + V G L F +L+ + +
Sbjct: 66 VVMFLFIIGLEMYPERLWAMRKAIFGRGLLQVGLCGCLLTFSGIYLLG---LTKEVSFIA 122
Query: 112 GAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISML---REGSV 168
G T +S +I ++ L E G T +G +++ + +D+ + +L V + +E +
Sbjct: 123 GMGFTLSSTAIVMQSLEERGLTSTSKGQRVISTLIFEDIAIVPLLASVAFLAPHSKEATP 182
Query: 169 HYD-VIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAE 227
H D V + + L L V G +M +FR +SK + E T+ A++ ++ A E
Sbjct: 183 HTDWVSIGIALSAVVGLIV---TGKWLMNPLFRLISKARIREMMTAGALLVVLGAALAME 239
Query: 228 HLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKT 287
L+ +GA++ G+ + +++++ ++E + + + +FF+ VGM +D +F
Sbjct: 240 IGGLSMAMGAFVAGVMMSESAFRHQLEADIEPF-RGLLLGLFFMGVGMSLDLHLVFNHWI 298
Query: 288 FAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMI--STAMAAGVA 345
++ K + A +++ D R + IG + G E A + S A A V
Sbjct: 299 LLLGIVFLYILGKASAVYIIARITRLDHREA--IGRMSLMAHGGEFAFVLFSAAATAEVI 356
Query: 346 GSDVLTVAMTMVFLTTLITPIM 367
++ V ++ L +PI+
Sbjct: 357 SNEEQATFTAAVIISMLFSPII 378
>sp|P45522|KEFB_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN KEFB
(K(+)/H(+) ANTIPORTER) (NEM-ACTIVATABLE K+/H+
ANTIPORTER) >gi|7444645|pir||A65129
glutathione-regulated potassium-efflux system protein
kefB - Escherichia coli (strain K-12)
>gi|606284|gb|AAA58147.1| (U18997) ORF_f601 [Escherichia
coli] >gi|1789749|gb|AAC76375.1| (AE000411) K+ efflux;
NEM-activable K+/H+ antiporter [Escherichia coli K12]
Length = 601
Score = 92.1 bits (225), Expect = 1e-17
Identities = 86/371 (23%), Positives = 181/371 (48%), Gaps = 14/371 (3%)
Query: 6 MLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVLMLL 61
+L L AVA + + R VLG ++AG+ +G I + I+ F+ LGV+ L+
Sbjct: 11 VLFLFAAVAAVP--LASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLM 68
Query: 62 FLAGLESDFEEFKRVGRPSILVASVGVLF-AFLFGFLIAYPFFDFGTALLYGAIMTPTSV 120
F+ GLE + + ++ R V + VL A L L+ F + A++ G + +S
Sbjct: 69 FIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAMSST 128
Query: 121 SITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEV 180
++ ++++ E G R++ G + + D+ I L +V + H+D ++V ++V
Sbjct: 129 AMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFD-WMKVGMKV 187
Query: 181 AGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLI 240
F+ + L G ++ VFR ++ + E T+ ++ ++ A + L L+ LG ++
Sbjct: 188 LAFVGM-LIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIA 246
Query: 241 GLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISK 300
G+ + ++ Y+ +E ++ + + +FF+ VGM ++ L+ + + V + K
Sbjct: 247 GVLLAESEYRHELETAIDPF-KGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVK 305
Query: 301 VIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMI--STAMAAGVAGSDVLTVAMTMVF 358
++ L A L + R+S ++ + G E A + STA + + D + + + V
Sbjct: 306 ILVLYLLARL--YGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVT 363
Query: 359 LTTLITPIMLR 369
L+ + TP++++
Sbjct: 364 LSMMTTPLLMK 374
>pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus
>gi|2983090|gb|AAC06696.1| (AE000689) NA(+)/H(+)
antiporter [Aquifex aeolicus]
Length = 387
Score = 92.1 bits (225), Expect = 1e-17
Identities = 95/384 (24%), Positives = 181/384 (46%), Gaps = 44/384 (11%)
Query: 9 LMLAVAKLSGWVFERFNQ----PIVLGQIIAGVIMGLL---IERNEIIVEFANLGVLMLL 61
L L + LS ++ F++ P+ +G++I G+++G I+ EI+ ++ G L+L+
Sbjct: 11 LFLIIVFLSAFLAPLFSRILRMPVPVGELIFGILIGNFFVGIQVPEILNFLSDFGFLLLM 70
Query: 62 FLAGLESDFEEFKRVGRP--SILVASVGVLF--AFLFGFLIAYPFFDFGTALLYGAIMTP 117
FLAGLE DF ++ + ++ ++ V ++F AF+FG L+ GTA I++
Sbjct: 71 FLAGLELDFNLIEKADKKQNAVYISYVLLIFLSAFVFGILLG-----IGTA--PAIILSL 123
Query: 118 TSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVL 177
S+ + V L ++ L +L V +++ +L LT++ +L H+ V ++
Sbjct: 124 ISLGLMVATLKDMSVLEEPFAKKVLLIGVFGEIISLLALTLMEKLL-----HFHGFVSLI 178
Query: 178 LEVAGFLAVF-------LYLGPVVM---ENVFRRLSKVDLPESTTSFAIVFLV----LFA 223
E+ G + VF YL +++ + RL+ + P + +FL+ +FA
Sbjct: 179 KEL-GVIFVFFFSFFLGFYLTRLLVWWYPEIVNRLTYEEDPSALGIRLSLFLMFTSSIFA 237
Query: 224 YLAEHLNLASILGAYLIGLSIGQ-TSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFL 282
LA + S+LGA++ G+ KK +E ++ IGY IP+FF++ GM ++ L
Sbjct: 238 KLA---GIESVLGAFMAGVVFSYFIREKKDLEEKLSSIGYGFLIPIFFIKTGMGMEVAGL 294
Query: 283 FEAKTF-AFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMA 341
A F F++ F + ++I L+ F + S G+ + + +A I A
Sbjct: 295 NLAILFKVFIFLAFMLFVRLIP-SFVLLLAGFSLKDSFTAGLLLSYPFTLMVAGIEIARR 353
Query: 342 AGVAGSDVLTVAMTMVFLTTLITP 365
G + ++L+ P
Sbjct: 354 GGALDEETALALFLTAAFSSLVFP 377
>sp|P03819|KEFC_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN KEFC
(K(+)/H(+) ANTIPORTER) >gi|2145008|pir||QQECRD
glutathione-regulated potassium efflux system protein
kefC [validated] - Escherichia coli
>gi|41875|emb|CAA40066.1| (X56742) KefC potassium efflux
system [Escherichia coli] >gi|216472|dbj|BAA01323.1|
(D10483) kefc potassium efflux system [Escherichia coli]
>gi|1786232|gb|AAC73158.1| (AE000115) K+ efflux
antiporter, glutathione-regulated [Escherichia coli K12]
Length = 620
Score = 91.7 bits (224), Expect = 1e-17
Identities = 79/291 (27%), Positives = 133/291 (45%), Gaps = 13/291 (4%)
Query: 3 TLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERNEIIVEFANLGVL 58
TL+ + L A L + R VLG +IAG I+G L+ E I+ FA +GV+
Sbjct: 5 TLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVV 64
Query: 59 MLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFG----TALLYGAI 114
++LF+ GLE D + R+ + V G L + G L+ G A L G
Sbjct: 65 LMLFIIGLELDPQ---RLWKLRAAVFGCGALQMVICGGLLGLFCMLLGLRWQVAELIGMT 121
Query: 115 MTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGI-LILTIVISMLREGSVHYDVI 173
+ +S +I ++ + E + T+ G + A + D+ I L+ I + S
Sbjct: 122 LALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAF 181
Query: 174 VEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLAS 233
L+VAG L + + LG V R +++ L E ++ A+ + F L E + L+
Sbjct: 182 ALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSM 241
Query: 234 ILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFE 284
+GA+L G+ + + Y+ +E + + + +FF+ VGM ID L E
Sbjct: 242 AMGAFLAGVLLASSEYRHALESDIEPF-KGLLLGLFFIGVGMSIDFGTLLE 291
>pir||G75431 probable Na+/H+ antiporter - Deinococcus radiodurans (strain R1)
>gi|6458886|gb|AAF10721.1|AE001964_5 (AE001964) Na+/H+
antiporter, putative [Deinococcus radiodurans]
Length = 383
Score = 90.9 bits (222), Expect = 2e-17
Identities = 90/348 (25%), Positives = 170/348 (47%), Gaps = 25/348 (7%)
Query: 33 IIAGVIMGLLIERNEIIVEF----ANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGV 88
++AG+ +G + ++ +F A +G ++LLF+ GLE +E + + + + + +
Sbjct: 35 LMAGIGLGTFMHLDDTAEKFIHTGAEIGAILLLFILGLEYTSDELRTNLKANRQIGLIDL 94
Query: 89 LFAF----LFGFLIAYPFFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAA 144
F + G L+ P + +L G I TS I K+L +LG+L +E ILA
Sbjct: 95 ALNFTPGVVAGALLGLPPLAW---VLLGGITFLTSSGIASKILSDLGRLGNRETPIILAV 151
Query: 145 AVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSK 204
V++DV+ L +V ++L GS+ V V + L + F F + +V R+
Sbjct: 152 CVIEDVVMAFYLPVVAALLIGGSL-LSVGVNLALALTAFGVTFFL--AMRYGHVLSRVLN 208
Query: 205 VDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSI-GQTSYKKRIE-GPMNVIGY 262
V E+ + +++ A A+ L +++ +GA+L+G+++ G+ +++ R + P+
Sbjct: 209 VPSDETLLLGVLGLVLVVAGAADLLKVSAAIGAFLVGIALSGEVAHRARQQIEPLR---- 264
Query: 263 SIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIG 322
+F VFF+ G+++D + E A L AV I+K + GA + R + G
Sbjct: 265 DLFAAVFFLFFGLQLDLAEVPEVLLPAALLAVVTSITKFLVGWYGARRAGVQSRGRYRAG 324
Query: 323 IGMIPRLGVELAMISTAMAAGVAGSDVL-TVAMTMVFLTTLITPIMLR 369
+I R E +++ + G+A VL +A V LT +I P++ R
Sbjct: 325 TTLIAR--GEFSILIAGLGLGLA--PVLGPLAAVYVLLTAIIGPVLAR 368
>pir||G75282 probable glutathione-regulated potassium-efflux system protein KefB
- Deinococcus radiodurans (strain R1)
>gi|6460182|gb|AAF11914.1|AE002067_6 (AE002067)
glutathione-regulated potassium-efflux system protein
KefB, putative [Deinococcus radiodurans]
Length = 575
Score = 90.5 bits (221), Expect = 3e-17
Identities = 96/380 (25%), Positives = 176/380 (46%), Gaps = 31/380 (8%)
Query: 7 LALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVLMLLF 62
L L+L VA + + R ++G + AGV+ G +I+ +I + +GV++LLF
Sbjct: 39 LTLLLLVAGATAFASFRLGLVPIIGFLFAGVLAGPSALGIIDDPALIGAASEIGVMLLLF 98
Query: 63 LAGLESDFEEFKRVGRPSILVASVGVLF--AFLFGFLIAYPFFDFGTALLYGAIMTPTSV 120
G+E ++ R+ R + + VL A + G L+A+ A+ G +++ +S
Sbjct: 99 TIGIEFSLDKLARIFRLIFVGGGLQVLLTVAAVTGVLLAFG-VSLPNAVFTGFLLSLSST 157
Query: 121 SITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEV 180
+I K+L G + + G L + D L ++++ +++ ML +V LL+
Sbjct: 158 AIVTKILESRGGVGSPTGQASLGILIFQD-LAVVVMVLLVPMLAGQGGGAGGLVVALLKA 216
Query: 181 AGFLAVFLYLG----PVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILG 236
G +A L L P ++E V R S+ ST S AYL ++ LG
Sbjct: 217 GGIVAAVLLLARRVVPKLLEVVARTCSQEIFLLSTLSLCFA----TAYLTSLAGVSLALG 272
Query: 237 AYLIGLSIGQTSYKKRIEG---PMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAF-LY 292
A+L GL + ++ + ++ G P+ + +F FF+ VG+++D FL+
Sbjct: 273 AFLAGLLVSESRFGQQAFGEILPLQI----LFSAAFFLSVGLQLDLGFLWTHLPLVLGAV 328
Query: 293 AVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLG-VELAMISTAMAAGVAGSDV-L 350
AVFA++ K + L L F T+ G ++ ++G + S+ A G++ + +
Sbjct: 329 AVFAVL-KALAAALSVRLLGFPLATAAATG-WLLAQVGEFSFVLESSGRALGLSPAGLGE 386
Query: 351 TVAMTMVFLTTL---ITPIM 367
T T + T L +TP+M
Sbjct: 387 TGTQTFIAATVLLMALTPVM 406
>pir||H81265 probable transmembrane transport protein Cj1684c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6969099|emb|CAB73670.1| (AL139079) putative
transmembrane transport protein [Campylobacter jejuni]
Length = 391
Score = 88.2 bits (215), Expect = 1e-16
Identities = 91/384 (23%), Positives = 172/384 (44%), Gaps = 34/384 (8%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL--IERNEIIVEFANLGVL 58
++ L+++AL L S + + P+ +II G I+ I ++E AN+G
Sbjct: 14 LKILIVIALCLL---FSPHIAKILRLPLSATEIILGAIIAHFGFIGKSENFALLANVGFY 70
Query: 59 MLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLYGAIMTPT 118
L+F+AG+E + F + + +A + FL L ++ + FG +L++ I+
Sbjct: 71 YLMFIAGMEVNLRAFFNMDKE---IAKKSFFYIFLLYALSSFIVWIFGLSLVFVIIIPVM 127
Query: 119 SVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLL 178
SV + + + GK ++ A + + V+ I++LTI + LREG+ DV +L
Sbjct: 128 SVGLLSLLFKDFGKECYWLNIAMIVATLAE-VISIVLLTIAGAFLREGTGIIDVAQSIL- 185
Query: 179 EVAGFLAVFL---YLGPVVMENVF---RRLSKVDLP-----ESTTSFAIVFLVLFAYLAE 227
+L +FL LG ++ +F +L V +P E F + +L
Sbjct: 186 ----YLNIFLGLCLLGFKMLGVLFWWYPQLKVVLMPWEDKNEKDIRFCMAIFILIIVAMV 241
Query: 228 HLNLASILGAYLIGLSIGQT-SYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAK 286
L +LG+++ G I +KK +E ++ G+ IP+FF+ +G D + + + K
Sbjct: 242 ITKLEIVLGSFIAGSFIATFFDHKKDLEHKLSTFGHGFLIPIFFIHIGSTFDLKMILDYK 301
Query: 287 TF--AFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGV 344
AFL +F M+ I C +L + ++ I G+ + L ++ G
Sbjct: 302 IVLQAFL-LMFVMVGLRILCA-SVFLKRIGFKNMILFGLSH----SMPLTLLIATATLGY 355
Query: 345 AGSDVLTVAMTMVFLTTLITPIML 368
+G + + + LT L I++
Sbjct: 356 SGKVIDEKLYSALILTALFEAIIV 379
>pir||B69146 gluthatione-regulated K+/H+ antiporter - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621417|gb|AAB84864.1| (AE000821)
gluthatione-regulated K+/H+ antiporter [Methanobacterium
thermoautotrophicum]
Length = 512
Score = 87.4 bits (213), Expect = 2e-16
Identities = 80/346 (23%), Positives = 146/346 (42%), Gaps = 20/346 (5%)
Query: 27 PIVLGQIIAGVIMGLLIERNEIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASV 86
P VLG + +G I L A LGV++LLF GLE E F R +++ ++
Sbjct: 8 PSVLGAVSSGSIESL-----------AELGVILLLFTIGLEMSAERFGEFRRTALIGGTL 56
Query: 87 GV-LFAFLFGFLIAYPFFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAA 145
+ L + L G A+ G +++ +S ++ +KVL + + G LA
Sbjct: 57 QICLTVSVVTILTMVLGLSPGKAVFLGFLISLSSTAVVLKVLQDFHETEAPHGQASLAIL 116
Query: 146 VVDDVLGI-LILTIVISMLREGSVHYDV--IVEVLLEVAGFLAVFLYLGPVVMENVFRRL 202
+ DV + +ILT+ G V D + LL L +G V++ +F +
Sbjct: 117 IFQDVAAVPMILTVPFL----GGVVGDPSSALGTLLTAGAVLPWEPCIGKVLVPRLFDVV 172
Query: 203 SKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGY 262
+ E I+ +L + L+ LGA+L+G + T Y R +G +
Sbjct: 173 AATGSREIFLLTVILVCASVTWLTGEVGLSPALGAFLVGSIVANTEYAHRAQGTILPF-Q 231
Query: 263 SIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIG 322
+F+ FFV +GM +D RF + L + ++ KV+ L ++ + R + +G
Sbjct: 232 EVFLSFFFVSLGMLLDLRFFLDHIYLIVLAVIGVLMIKVVMNSLVGFVMGYSARVVVLLG 291
Query: 323 IGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLTTLITPIML 368
+ + + T + G+ +++ +T ITP ++
Sbjct: 292 LVLAQIGEFSFILSETGLRYGLMDRLTFQAFLSVSLITMAITPFLI 337
>gb|AAD01191.1| (AF003382) KEA1 [Arabidopsis thaliana]
Length = 618
Score = 87.0 bits (212), Expect = 3e-16
Identities = 87/362 (24%), Positives = 174/362 (48%), Gaps = 38/362 (10%)
Query: 29 VLGQIIAGVIMG---LLIERN----EIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSI 81
VLG + AG+++G L I RN I EF GV++LLF GLE E + +
Sbjct: 40 VLGYLAAGILIGPYGLSIIRNVHGTRAIAEF---GVVLLLFNIGLELSVERLSSMKKYVF 96
Query: 82 LVASVGVLF-AFLFGFLIAYPFFDFG-TALLYGAIMTPTSVSITVKVLMELGKLRTKEGA 139
+ S VL A + G L Y G A++ G + +S ++ ++VL E G+ ++ G
Sbjct: 97 GLGSAQVLVTAAVVGLLAHYVAGQAGPAAIVIGNGLALSSTAVVLQVLQERGESTSRHGR 156
Query: 140 TILAAAVVDDVLGILILTIVISMLR----EGSVHYDVIVEVL----LEVAGFLAVFLYLG 191
+ + D L +++L I+I ++ +G + + I E L ++ A + + G
Sbjct: 157 ASFSVLLFQD-LAVVVLLILIPLISPNSSKGGIGFQAIAEALGLAAVKAAVAITAIIAGG 215
Query: 192 PVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQTSYKK 251
+++ +++++++ E ++ ++ ++ + L L+ LGA+L GL + +T +
Sbjct: 216 RLLLRPIYKQIAENRNAEIFSANTLLVILGTSLLTARAGLSMALGAFLAGLLLAETEFSL 275
Query: 252 RIEGPMNVIGY-SIFIPVFFVEVGMRIDPRFLFE-----AKTFAFLYAVFAMISKVIGCG 305
++E ++ Y + + +FF+ VGM IDP+ L T L M+ ++G
Sbjct: 276 QVES--DIAPYRGLLLGLFFMTVGMSIDPKLLLSNFPVIVGTLGLLIVGKTMLVVIMGKL 333
Query: 306 LGAYLSKFDWRTSIKIGIGMIPRLGVELAMIS--TAMAAGVAGSDVLTVAMTMVFLTTLI 363
G + ++I++G+ + P G E A ++ A+ G+ + ++ +V ++ I
Sbjct: 334 FGISII-----SAIRVGLLLAP--GGEFAFVAFGEAVNQGIMSPQLSSLLFLVVGISMAI 386
Query: 364 TP 365
TP
Sbjct: 387 TP 388
>gb|AAF78418.1|AC009273_24 (AC009273) Identical to K efflux antiporter mRNA from Arabidopsis
thaliana gb|AF003382. It contains a TrkA potassium
uptake protein PF|02080 domain. ESTs gb|T44799,
gb|AA395270 and gb|AI997899 come from this gene
Length = 618
Score = 86.2 bits (210), Expect = 6e-16
Identities = 87/362 (24%), Positives = 173/362 (47%), Gaps = 38/362 (10%)
Query: 29 VLGQIIAGVIMG---LLIERN----EIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSI 81
VLG + AG+++G L I RN I EF GV+ LLF GLE E + +
Sbjct: 40 VLGYLAAGILIGPYGLSIIRNVHGTRAIAEF---GVVFLLFNIGLELSVERLSSMKKYVF 96
Query: 82 LVASVGVLF-AFLFGFLIAYPFFDFG-TALLYGAIMTPTSVSITVKVLMELGKLRTKEGA 139
+ S VL A + G L Y G A++ G + +S ++ ++VL E G+ ++ G
Sbjct: 97 GLGSAQVLVTAAVVGLLAHYVAGQAGPAAIVIGNGLALSSTAVVLQVLQERGESTSRHGR 156
Query: 140 TILAAAVVDDVLGILILTIVISMLR----EGSVHYDVIVEVL----LEVAGFLAVFLYLG 191
+ + D L +++L I+I ++ +G + + I E L ++ A + + G
Sbjct: 157 ASFSVLLFQD-LAVVVLLILIPLISPNSSKGGIGFQAIAEALGLAAVKAAVAITAIIAGG 215
Query: 192 PVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQTSYKK 251
+++ +++++++ E ++ ++ ++ + L L+ LGA+L GL + +T +
Sbjct: 216 RLLLRPIYKQIAENRNAEIFSANTLLVILGTSLLTARAGLSMALGAFLAGLLLAETEFSL 275
Query: 252 RIEGPMNVIGY-SIFIPVFFVEVGMRIDPRFLFE-----AKTFAFLYAVFAMISKVIGCG 305
++E ++ Y + + +FF+ VGM IDP+ L T L M+ ++G
Sbjct: 276 QVES--DIAPYRGLLLGLFFMTVGMSIDPKLLLSNFPVIVGTLGLLIVGKTMLVVIMGKL 333
Query: 306 LGAYLSKFDWRTSIKIGIGMIPRLGVELAMIS--TAMAAGVAGSDVLTVAMTMVFLTTLI 363
G + ++I++G+ + P G E A ++ A+ G+ + ++ +V ++ I
Sbjct: 334 FGISII-----SAIRVGLLLAP--GGEFAFVAFGEAVNQGIMSPQLSSLLFLVVGISMAI 386
Query: 364 TP 365
TP
Sbjct: 387 TP 388
>pir||F70591 probable kefB protein - Mycobacterium tuberculosis (strain H37RV)
>gi|2072703|emb|CAB08337.1| (Z95121) kefB [Mycobacterium
tuberculosis]
Length = 385
Score = 83.9 bits (204), Expect = 3e-15
Identities = 93/376 (24%), Positives = 169/376 (44%), Gaps = 18/376 (4%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL-----LIERNEIIVEFANLGVL 58
L L ++LAV + G V RF + ++AG+ +G + E I A +GV+
Sbjct: 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67
Query: 59 MLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLYGAIMTPT 118
+LL GLE EF R + A V ++ G + + G A+L A +T
Sbjct: 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127
Query: 119 SVS-ITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVL 177
S S + ++L +L +L +E +L+ V++D L + + +GS + +V +
Sbjct: 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGS-WLEAVVGMT 186
Query: 178 LEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGA 237
+ +A L F +V R ++ D + + L++ A +AE L+ ++ +GA
Sbjct: 187 VAIAALLGAFA-ASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAA-VAESLHASAAVGA 244
Query: 238 YLIGLSI-GQTSYKKR-IEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVF 295
+L+GL++ G+T+ + R + P+ +F +FF+ +G+ +DP L A A
Sbjct: 245 FLVGLTLTGETADRARMVLTPLR----DLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300
Query: 296 AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMT 355
+KV A R ++ G ++ R L +I AG + V +A
Sbjct: 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIG---LAGASIPGVAALATA 357
Query: 356 MVFLTTLITPIMLRKT 371
VF+ ++ PI+ R T
Sbjct: 358 YVFVMAIVGPILARYT 373
>pir||T01227 glutathione-regulated potassium-efflux system protein kefB homolog
F6N23.15 - Arabidopsis thaliana
>gi|3047127|gb|AAC13638.1| (AF058919) F6N23.15 gene
product [Arabidopsis thaliana]
>gi|7267402|emb|CAB80872.1| (AL161472) putative
potassium/H+ antiporter [Arabidopsis thaliana]
Length = 617
Score = 83.5 bits (203), Expect = 4e-15
Identities = 84/348 (24%), Positives = 165/348 (47%), Gaps = 30/348 (8%)
Query: 29 VLGQIIAGVIMG---LLIERN----EIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSI 81
VLG + AG+++G L I RN + I EF GV+ LLF GLE E + +
Sbjct: 48 VLGYLAAGILIGPYGLSIIRNVHGTKAIAEF---GVVFLLFNIGLELSVERLSSMKKYVF 104
Query: 82 LVASVGVLF-AFLFGFLIAYPFFDFG-TALLYGAIMTPTSVSITVKVLMELGKLRTKEGA 139
+ S VL A + G + Y G A++ G + +S ++ ++VL E G+ ++ G
Sbjct: 105 GLGSAQVLVTAAVIGLITHYVAGQAGPAAIVIGNGLALSSTAVVLQVLQERGESTSRHGR 164
Query: 140 TILAAAVVDDVLGILILTIVISMLR----EGSVHYDVIVEVL----LEVAGFLAVFLYLG 191
+ + D L +++L I+I ++ +G + + I E L ++ A + + G
Sbjct: 165 ATFSVLLFQD-LAVVVLLILIPLISPNSSKGGIGFQAIAEALGLAAIKAAVAITGIIAGG 223
Query: 192 PVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQTSYKK 251
+++ +++++++ E ++ ++ ++ + L L+ LGA+L GL + +T +
Sbjct: 224 RLLLRPIYKQIAENRNAEIFSANTLLVILGTSLLTARAGLSMALGAFLAGLLLAETEFSL 283
Query: 252 RIEGPMNVIGY-SIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISKVIGCGLGAYL 310
++E ++ Y + + +FF+ VGM IDP+ L ++ K I + L
Sbjct: 284 QVES--DIAPYRGLLLGLFFMTVGMSIDPKLLLANFPLIMGTLGLLLVGKTILVVIIGKL 341
Query: 311 SKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMTMVF 358
+++++G+ + P G E A + A G A + V+ M VF
Sbjct: 342 FGISIISAVRVGLLLAP--GGEFAFV----AFGEAVNQVIIYMMISVF 383
>dbj|BAB11240.1| (AB010074) potassium/proton antiporter-like protein [Arabidopsis
thaliana]
Length = 562
Score = 83.1 bits (202), Expect = 5e-15
Identities = 79/376 (21%), Positives = 163/376 (43%), Gaps = 18/376 (4%)
Query: 7 LALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERNEIIVEFANLGVLMLLF 62
L +++ A + G VF QP+++G ++AG I+G I + A GV+ LLF
Sbjct: 158 LVVIIVFAAIGGIVFSCLGQPVIVGYLLAGSIIGPGGLKFISEMVQVETVAQFGVVFLLF 217
Query: 63 LAGLESDFEEFKRVGRPSILVASVG-VLFAFLFGFLIAYPFFDFGTALLYGAIMTPTSVS 121
GLE + K VG ++L + VL FL G + GA ++ +S +
Sbjct: 218 ALGLEFSMTKLKVVGPVAVLGGLLQIVLLMFLCGVTALLCGARLSEGIFVGAFLSMSSTA 277
Query: 122 ITVKVLMELGKLRTKEGATILAAAVVDD-VLGILILTIVISMLREGSVHYDVIVEVLLEV 180
+ VK L+E + G + + D V+G+L + + G + + + LL +
Sbjct: 278 VVVKFLVERNSTSSLHGQVTIGILIFQDCVVGLLFALLPVLGGNSGLLQGIISMGKLLLI 337
Query: 181 AGFLAVFLYLGPVVMENVFRRLSK--VDLPESTTSF----AIVFLVLFAYLAEHLNLASI 234
L+++L + ++ + R K + L T A+ F +L A+ ++ L L+
Sbjct: 338 ---LSIYLTVASLLTWSFVPRFLKLMIQLSSQTNELYQLAAVAFCLLSAWCSDKLGLSLE 394
Query: 235 LGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAV 294
LG+++ G+ + T + + + ++ F +GM I+ FL+ +
Sbjct: 395 LGSFVAGVMLSTTEFAQHTLEQVLILNSGRFC-FASTCIGMLINVHFLWNHVDILLASVI 453
Query: 295 FAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLG-VELAMISTAMAAGVAGSDVLTVA 353
++ K + +++ R S +G+ ++ ++G ++S A V + +
Sbjct: 454 LVIVIKTAIAAVVVKAFRYNMRISFHVGV-LLAQIGEFAFVLLSRASNLHVIEGKMYLLL 512
Query: 354 MTMVFLTTLITPIMLR 369
+ L+ + TP++ +
Sbjct: 513 LGTTALSLVTTPLLFK 528
>gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]
Length = 505
Score = 82.7 bits (201), Expect = 6e-15
Identities = 92/382 (24%), Positives = 175/382 (45%), Gaps = 27/382 (7%)
Query: 3 TLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVL 58
+LL L +ML AK+S +F R +G I+ G+++G +I+ NEII +LG++
Sbjct: 8 SLLYLGIMLIAAKISEEIFRRIGLVTFVGPILMGILLGNGVFGVIQINEIISFITSLGIV 67
Query: 59 MLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFL--FGFLIAYPFFDFGTALLYGAIMT 116
LLFLAG EEF RP+ V +L + + L+A F L+ +
Sbjct: 68 FLLFLAGA----EEFNVENRPNANVFLAVILESIIPFSVILVAIYIIGFKNYLILIVPLA 123
Query: 117 PTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEV 176
+S ++LM++ K+ + ++ V +L +I I+ ++L + S I+E+
Sbjct: 124 MSSAGPLSRMLMDV-KISDNRISNLIFQQV---ILIEIIFVILFAILLKTSEILITIIEI 179
Query: 177 LLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILG 236
L V F +F ++E + ++ E + AI+ ++ YLAE S +
Sbjct: 180 FL-VFAFTIMFGRTLAKILEKIEYYFKAREI-EFASLIAIILII--GYLAELYKFNSAIS 235
Query: 237 AYLIGLSIGQTSYKKRIE--GPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAV 294
A+ +G+ + + K R E ++ Y F P+FF+ +G+ + A F
Sbjct: 236 AFFLGILL-KDYLKDRPELLERLHAFTYGFFEPLFFLGIGLYVTK---INASIILFSLLF 291
Query: 295 FAMISKVIGCGLGAYLSKFDWRTSIKI-GIGMIPRLGVELAMISTAMAAGVAGSDVLTVA 353
F++I + L ++S KI G + GV+ +++ T + G + + +
Sbjct: 292 FSLI--IASKFLAGFISSKILNIKGKINGFATSVKGGVDSSLLLTGLTLGYINEFMYSFS 349
Query: 354 MTMVFLTTLITPIMLRKTYIIT 375
+ + L+ LI P++ + + I+
Sbjct: 350 ILAISLSALIVPLLFQINFKIS 371
>pir||B81225 glutathione-regulated potassium-efflux system protein NMB0209
[imported] - Neisseria meningitidis (group B strain
MD58) >gi|7225431|gb|AAF40666.1| (AE002378)
glutathione-regulated potassium-efflux system protein
[Neisseria meningitidis MC58]
Length = 658
Score = 82.7 bits (201), Expect = 6e-15
Identities = 73/373 (19%), Positives = 160/373 (42%), Gaps = 9/373 (2%)
Query: 3 TLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERNEIIVEFANLGVL 58
+L + ++L V+ ++ + +FN P +LG ++ G + G LI ++ +G++
Sbjct: 5 SLAPIVIVLLVSVITVILCRKFNIPSMLGYLLVGFLAGPGMLSLIPKSHATDYLGEIGIV 64
Query: 59 MLLFLAGLESDFEEFKRVGRPSILVAS--VGVLFAFLFGFLIAYPFFDFGTALLYGAIMT 116
L+F GLE + + + R + VG+ + G L+ F A +
Sbjct: 65 FLMFSIGLEFSLPKLRAMRRLVFGLGGLQVGITMLSVMGILMLTGV-PFNWAFAVSGALA 123
Query: 117 PTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVH-YDVIVE 175
+S +I ++L E +L G + ++ D+ + ++ ++ ++ G + + +
Sbjct: 124 MSSTAIVSRILSEKTELGQPHGQMAMGVLLMQDIAVVPLMILIPALAGGGDGNIWAALGL 183
Query: 176 VLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASIL 235
++ L + ++G +M FR ++K E ++ + AYL E L+ L
Sbjct: 184 AFAKMLLTLGLLFFVGSKIMSRWFRMVAKRKSSELFMINVLLVTLGVAYLTELEGLSMAL 243
Query: 236 GAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVF 295
GA++ G+ + +T Y+ ++E + I + FF+ VGM++D + L +
Sbjct: 244 GAFVAGMLLSETEYRFQVEDDIRPF-RDILLGFFFITVGMKLDIQALIGGWRQVLMLLAM 302
Query: 296 AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMT 355
++ K + A+ K S+K + + M++ A + + A
Sbjct: 303 LLVLKALVVFAIAFKMKHSVGDSLKTALYLAQGGEFGFVMLAIAGQLDMVSPEWEQAATA 362
Query: 356 MVFLTTLITPIML 368
V L+ +I P +L
Sbjct: 363 AVLLSMIIAPFLL 375
>pir||C81997 probable glutathione-regulated potassium-efflux system protein
NMA0060 [imported] - Neisseria meningitidis (group A
strain Z2491) >gi|7378833|emb|CAB83376.1| (AL162752)
putative transmembrane transport protein [Neisseria
meningitidis Z2491]
Length = 658
Score = 82.7 bits (201), Expect = 6e-15
Identities = 74/373 (19%), Positives = 160/373 (42%), Gaps = 9/373 (2%)
Query: 3 TLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERNEIIVEFANLGVL 58
+L + ++L V+ ++ + +FN P +LG ++ G + G LI ++ +G++
Sbjct: 5 SLAPIVIVLLVSVITVILCRKFNIPSMLGYLLVGFLAGPGMLSLIPKSHATDYLGEIGIV 64
Query: 59 MLLFLAGLESDFEEFKRVGRPSILVAS--VGVLFAFLFGFLIAYPFFDFGTALLYGAIMT 116
L+F GLE + + + R + VGV + G L+ F A +
Sbjct: 65 FLMFSIGLEFSLPKLRAMRRLVFGLGGLQVGVTMLSVMGILMLTGV-PFNWAFAVSGALA 123
Query: 117 PTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVH-YDVIVE 175
+S +I ++L E +L G + ++ D+ + ++ ++ ++ G + + +
Sbjct: 124 MSSTAIVSRILSEKTELGQPHGQMAMGVLLMQDIAVVPLMILIPALAGGGDGNIWAALGL 183
Query: 176 VLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASIL 235
++ L + ++G +M FR ++K E ++ + AYL E L+ L
Sbjct: 184 AFAKMLLTLGLLFFVGSKIMSRWFRMVAKRKSSELFMINVLLVTLGVAYLTELEGLSMAL 243
Query: 236 GAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVF 295
GA++ G+ + +T Y+ ++E + I + FF+ VGM++D + L +
Sbjct: 244 GAFVAGMLLSETEYRFQVEDDIRPF-RDILLGFFFITVGMKLDIQALIGGWRQVLMLLAM 302
Query: 296 AMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAMT 355
++ K + A+ K S+K + + M++ A + + A
Sbjct: 303 LLVLKALVVFAIAFKMKHSVGDSLKTALYLAQGGEFGFVMLAIAGQLDMVSLEWEQAATA 362
Query: 356 MVFLTTLITPIML 368
V L+ +I P +L
Sbjct: 363 AVLLSMIIAPFLL 375
>emb|CAB76285.1| (AL158057) putative transmembrane transport protein. [Streptomyces
coelicolor A3(2)]
Length = 446
Score = 81.1 bits (197), Expect = 2e-14
Identities = 89/385 (23%), Positives = 167/385 (43%), Gaps = 21/385 (5%)
Query: 2 ETLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG------LLIERNEIIVEFANL 55
+TLL + A + R P + ++AG+++G +L+E + L
Sbjct: 5 DTLLAMGGAFVAAAFLARLGGRIGLPTIPLFMLAGILLGPHTPGFVLVEDAHDFEMLSAL 64
Query: 56 GVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLF----AFLFGFLIAYPFFDFGTALLY 111
G+++LLF GLE ++ + G+ + + +L FGF++ + + AL+
Sbjct: 65 GLVLLLFYLGLEFHLDDLRSGGKRLLTAGGIYLLLNVGAGLGFGFVLGWGVRE---ALVL 121
Query: 112 GAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYD 171
++ +S +I K+L++LG++ E IL VV+D+ L L + ++ D
Sbjct: 122 AGVLGISSSAIVTKILIDLGRIGRPETRLILGVIVVEDIFLALYLAALQPVISGAHGVAD 181
Query: 172 VIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNL 231
++ + GFL V V R + D SF + VL A ++E L +
Sbjct: 182 TALQA-GKAFGFLLVLAAAARYGTRLVGRLIHTRDNELLVISF-LGAAVLVAGVSEVLGV 239
Query: 232 ASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFL 291
A +GA+++GL + T RI ++ + F +FF G+ IDP L
Sbjct: 240 ADAIGAFMVGLILAGTPSGPRIRELVHPL-RDAFAAIFFFAFGLAIDPGDLASVAGPVAA 298
Query: 292 YAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLT 351
A ++ ++ A + + + +I ++ R E A+I AMAAG AG D
Sbjct: 299 AAALTVVMNIVAGLCVARVYHYGSEPAAEIATTLVAR--GEFALILAAMAAG-AGLDAQL 355
Query: 352 VAMT--MVFLTTLITPIMLRKTYII 374
V + ++ PI+ + +++
Sbjct: 356 APFIAGYVLVLAVLGPIVAGRAHVL 380
>emb|CAB44437.1| (AJ242913) glutathione-gated K efflux system [Klebsiella aerogenes]
Length = 621
Score = 79.6 bits (193), Expect = 5e-14
Identities = 73/287 (25%), Positives = 132/287 (45%), Gaps = 17/287 (5%)
Query: 3 TLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERNEIIVEFANLGVL 58
TL+ + L A L + VLG +IAG I+G L+ E I+ FA +GV+
Sbjct: 5 TLIQALIYLGAAALIVPIASVLGLGSVLGYLIAGCIIGPWALRLVNDAEAILHFAEIGVV 64
Query: 59 MLLFLAGLESDFEEFKRVGRPSIL------VASVGVLFAFLFGFLIAYPFFDFGTALLYG 112
++L GLE D + ++ R S+ + + GVL LF L+ + A L G
Sbjct: 65 LMLVAMGLELDPQRLWKL-RASVFDGGALQMVACGVLIG-LFCMLLG---LRWQVAELIG 119
Query: 113 AIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGI-LILTIVISMLREGSVHYD 171
+ +S +I ++ + E ++ G + A + D+ I L+ I + G+
Sbjct: 120 MTLALSSTAIAMQAMNERNLTVSQMGRSAFAVLLFQDIAAIPLVAMIPLLAASGGATSLM 179
Query: 172 VIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNL 231
L+VA LA+ + LG + + R +++ L E ++ A + L E + L
Sbjct: 180 AFALSALKVAAALALVVVLGRYLTRPLLRFVARSGLREVFSAVACSWSSALGLLLEEVGL 239
Query: 232 ASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRID 278
+ +GA+L G+ + + Y+ +E + + + + +FF+ VGM ID
Sbjct: 240 SMAMGAFLAGVLLASSEYRHALENDIEPV-KGLLLGLFFIGVGMSID 285
>gb|AAD03448.1| (AF118223) contains similarity several bacterial
glutathione-regulated potassium efflux system proteins
[Arabidopsis thaliana]
Length = 735
Score = 78.8 bits (191), Expect = 9e-14
Identities = 77/352 (21%), Positives = 155/352 (43%), Gaps = 34/352 (9%)
Query: 29 VLGQIIAGVIM---GLLIERNEIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVAS 85
+LG AGV++ GL+ ++ V + G+L LLF GLE K + +
Sbjct: 123 ILGFFFAGVVLNQFGLIRNLTDVKV-LSEWGILFLLFEMGLELSLARLKALAK------- 174
Query: 86 VGVLFAFLFGFLIAYPFFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAA 145
FAF G L A++ GA ++ +S + +++L E G+L T+ G+ L
Sbjct: 175 ----FAFGMG-LTQVNIRSIDEAVVIGAALSLSSSAFVLQLLAEKGELPTRFGSATLGIL 229
Query: 146 VVDDVLGI---LILTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRL 202
++ D+ + +IL ++ S G + ++ + + G L + G + +F +
Sbjct: 230 LLQDIAVVPLLVILPVLESQDIGGESIWPMLAKESAKALGGLGILSLGGKFFLRRIFEVV 289
Query: 203 SKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGY 262
++ E+ + ++ + + + + L + LGA+L G + +T+++ +IE +
Sbjct: 290 AETRSSEAFVALCLLTVAGTSLVTQWLGFSDTLGAFLAGALLAETNFRTQIEADIRPF-R 348
Query: 263 SIFIPVFFVEVGMRIDPRFLFE-----AKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRT 317
+ + +FFV G ID LF L + +I IG +G + +
Sbjct: 349 GLLLGLFFVTTGTSIDMEVLFREWPNVLSLLGGLIVIKTLIITAIGPRVGLTIQE----- 403
Query: 318 SIKIGIGMIPRLGVELAMI--STAMAAGVAGSDVLTVAMTMVFLTTLITPIM 367
+ +G + G E A + S A GV +++ + + +V L+ +TP +
Sbjct: 404 --SVRVGFLLSQGGEFAFVVFSLANRLGVLPNELNKLLIIVVVLSMALTPYL 453
>pir||T36239 probable integral membrane efflux protein - Streptomyces coelicolor
>gi|4582390|emb|CAB40337.1| (AL049573) putative integral
membrane efflux protein [Streptomyces coelicolor A3(2)]
Length = 404
Score = 78.8 bits (191), Expect = 9e-14
Identities = 95/380 (25%), Positives = 167/380 (43%), Gaps = 46/380 (12%)
Query: 7 LALMLAVAKLSGWVFE----RFNQPIVLGQIIAGVIMGLLI----ERNEIIVEFANLGVL 58
L L+LA A L+ + R P+V+ +I G++MG + ++++ A+LG+
Sbjct: 7 LVLILAAAVLAPLLVHATGRRVRVPLVIFEISLGIVMGPDVLGWARPDDVVDTLADLGLS 66
Query: 59 MLLFLAGLESDFEEFK-RVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLYGAIMTP 117
ML+FLAG E DF + R S+ V ++ L++ D A + G +T
Sbjct: 67 MLIFLAGYEIDFAAVRGDTLRRSLWSWPVALVAGIALALLVSGG--DVFEAFVIGTALTS 124
Query: 118 TSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVL 177
T++ + +L + G+LR + G I A V + ++ + +++S R L
Sbjct: 125 TTLGTVLPMLRDSGELRGRFGTVISAFGAVGEFGPVIAVALLLSGRRPAE------SAAL 178
Query: 178 LEVAGFL---AVFLYLGPVVMENVFRRLSKVDLPES---TTSFAIVFLVLFAYLAEHLNL 231
L G + AVF L P F RL++ L S F ++ L LAE L
Sbjct: 179 LAAFGAITTAAVFWALRP--RPPWFARLTERTLHTSGQFAVRFVMLLLACMLGLAEVFGL 236
Query: 232 ASILGAYLIG------LSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRI-------D 278
+LGA+ G L + + G + +G+ +P+F+V G+ D
Sbjct: 237 DVLLGAFAAGVLTRLVLLRAAPASSGEVLGKVEAMGFGFLVPLFYVVTGIEFDLAALLHD 296
Query: 279 PRFLFEAKTFAFLY------AVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVE 332
P L F L+ V+ + + +G G A L+ F T + + + I +GV+
Sbjct: 297 PGALLLVPGFLLLFLLVHGGPVYLLAPRDLGRGDRAALALFT-STCLPLVVA-ITTIGVD 354
Query: 333 LAMISTAMAAGVAGSDVLTV 352
+I+T AA + G+ +++V
Sbjct: 355 QELIATDRAASLVGAAMVSV 374
>sp|P39830|YBAL_ECOLI HYPOTHETICAL 59.4 KD PROTEIN IN GSK-FSR INTERGENIC REGION
>gi|7444646|pir||E64778 probable membrane protein ybaL -
Escherichia coli >gi|1773160|gb|AAB40232.1| (U82664)
similar to Y. enterocolitica RosB [Escherichia coli]
>gi|1786685|gb|AAC73580.1| (AE000154) putative transport
protein [Escherichia coli K12]
Length = 558
Score = 75.3 bits (182), Expect = 1e-12
Identities = 78/374 (20%), Positives = 156/374 (40%), Gaps = 23/374 (6%)
Query: 11 LAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL----IERNEIIVEFANLGVLMLLFLAGL 66
L +A + G + + ++G ++AGV+ G + ++ E A LGV++L+F GL
Sbjct: 15 LVLAFILGMLANKLRISPLVGYLLAGVLAGPFTPGFVADTKLAPELAELGVILLMFGVGL 74
Query: 67 ESDFEEFKRVGRPSILVASVGVLFAFLFGF-LIAYPFFDFGTALLYGAIMTPTSVSITVK 125
++ V +I A + A L G L A + T +++G ++ S + ++
Sbjct: 75 HFSLKDLMAVKAIAIPGAIAQIAVATLLGMALSAVLGWSLMTGIVFGLCLSTASTVVLLR 134
Query: 126 VLMELGKLRTKEGATILAAAVVDD---VLGILILTIVISMLREGSVHYDVIVE----VLL 178
L E + ++ G + +V+D VL +++L V M+ +G V + + +
Sbjct: 135 ALEERQLIDSQRGQIAIGWLIVEDLVMVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIG 194
Query: 179 EVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLA-EHLNLASILGA 237
+V F+A+ + +G ++ + R + E T + + A+ A E +++ LGA
Sbjct: 195 KVIAFIAIMMLVGRRLVPWIMARSAATGSRELFTLSVLALALGVAFGAVELFDVSFALGA 254
Query: 238 YLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAM 297
+ G+ + ++ R + F +FFV VGM DP L + +
Sbjct: 255 FFAGMVLNESELSHRAAHDTLPL-RDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIIL 313
Query: 298 ISKVIGCGLGAYLSKFDWRTSIKIGIGM---------IPRLGVELAMISTAMAAGVAGSD 348
K + L RT++ I + + LG+ L ++ A V
Sbjct: 314 FGKSLAAFFLVRLFGHSQRTALTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGA 373
Query: 349 VLTVAMTMVFLTTL 362
+L++ + V L
Sbjct: 374 ILSIMLNPVLFALL 387
>emb|CAC12310.1| (AL445066) Na+/H+ antiporter related protein [Thermoplasma
acidophilum]
Length = 381
Score = 75.3 bits (182), Expect = 1e-12
Identities = 84/368 (22%), Positives = 168/368 (44%), Gaps = 23/368 (6%)
Query: 16 LSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLGVLMLLFLAGLESDFE 71
L G + +RF P V+ I++G+I+G +I ++ I + ++ + ++ G+E++ E
Sbjct: 2 LLGVLLDRFRIPEVVAYIVSGIIVGAGVLRIIMPSQTISDIESISLFFIILSIGVEANTE 61
Query: 72 EFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFG--TALLYGAIMTPTSVSITVKVLME 129
+ SIL G +F + G + FG + + ++ S+SI +LM+
Sbjct: 62 YIYGNLKRSILFTISGFIFPMILGLAVLNFISPFGFIPSFVVSLSVSVPSISIISVLLMK 121
Query: 130 LGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLY 189
L+ G IL++ V+ D++ ++L+ + ++ + +A F +
Sbjct: 122 YDLLKVNGGRLILSSVVLTDIVAFIMLSATTENVYHVLESLGFVILFFVVIAIFDIIIRR 181
Query: 190 LGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQTS- 248
+M + +R K ++ S I+ +L + + E + + +LG++ G+ I + S
Sbjct: 182 RAIGIMAWIEKREEKTNMEYILFSMIIIAGLLVSIIFEVIGITYVLGSFFAGILIHEASV 241
Query: 249 ---YKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISKVIGCG 305
Y + + + I S FIP+FF G+ + F FL A+ +I V G
Sbjct: 242 GEKYHRILVNTLKRINDSFFIPLFFSIAGISV--VFPHLDTFIIFLPALIVII--VSGTL 297
Query: 306 LGAYLSKFDWR-----TSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVA-MTMVFL 359
L LSK R T++ + +G +GV +A I A G+ S ++A + V +
Sbjct: 298 LNYALSKRFIRSITPLTTMSV-LGGRGAVGVIIAAI--AYDTGIITSIQYSLAILGTVLI 354
Query: 360 TTLITPIM 367
+ +ITP++
Sbjct: 355 SLIITPLI 362
>pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum pernix (strain K1)
>gi|5106130|dbj|BAA81441.1| (AP000064) 412aa long
hypothetical Na+/H+ antiporter [Aeropyrum pernix]
Length = 412
Score = 74.9 bits (181), Expect = 1e-12
Identities = 71/336 (21%), Positives = 146/336 (43%), Gaps = 23/336 (6%)
Query: 34 IAGVIMGLL-----IERNEIIVEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGV 88
+ +IMG + ++ E++ A +G +LLF+AG E D + + +++VA V
Sbjct: 84 VVEIIMGAMLAFWGVKSTEVLTLLAAIGANLLLFMAGSEIDLALLRSILPQAVIVALVSA 143
Query: 89 LFAF-LFGFLIAYPFFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVV 147
L L L Y ++L+ A ++ TSV++T +L +R++ G LA+A++
Sbjct: 144 LAPLALTALLHVYLGLSLTSSLVILASLSATSVALTYLLLSSYRLVRSRLGQLALASAML 203
Query: 148 DDVLGILILTIVISMLREGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDL 207
D+ G+++L I + + Y VI+ L +++ + RL
Sbjct: 204 LDLSGMIMLNIATASISPSLAFYIVIL---------------LAALLLYPLLPRLGGAPF 248
Query: 208 PESTTSFAIVFLVLFAYLAEHLNLASILGAYLIGLSIGQT-SYKKRIEGPMNVIGYSIFI 266
E+ + +++ +L++ + + S+L ++++G+ +T + ++ + + F
Sbjct: 249 -EAEIRLITMTVIILGFLSDFVGVHSVLTSFILGVIASETVRTRVQLREKLESLATGFFT 307
Query: 267 PVFFVEVGMRIDPRFLFEAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMI 326
P FF+ GM IDP A V +++ L+ R+S+
Sbjct: 308 PFFFIASGMSIDPGIPLHYVALALAGGVALALARTYTVYFYFRLTGSSRRSSLIAASSTA 367
Query: 327 PRLGVELAMISTAMAAGVAGSDVLTVAMTMVFLTTL 362
L V + S G+ S + +V + +V T L
Sbjct: 368 MLLTVTIIAASVGFQLGLLDSLMYSVLVWIVVGTIL 403
>pir||F69201 conserved hypothetical protein MTH760 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621849|gb|AAB85263.1| (AE000854) Na+/H+-exchanging
protein:Na+/H+ antiporter [Methanobacterium
thermoautotrophicum]
Length = 399
Score = 74.1 bits (179), Expect = 2e-12
Identities = 80/387 (20%), Positives = 175/387 (44%), Gaps = 28/387 (7%)
Query: 7 LALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERN--EIIVEFANLGVLML 60
+A+++ + L VF R P +LG +I G+++G LI ++ +I + + ++++
Sbjct: 8 VAVIILLGLLFNRVFTRARLPGILGMLILGILIGPHGLNLISKSIMDISPDLRVIALIII 67
Query: 61 LFLAGLESDFEEFKRVGRPSILVASV-----GVLFAFLFGFLIAYPFFDFGTALLYGAIM 115
L AG + E ++VG ++ ++ + G+ +++ P + G + G ++
Sbjct: 68 LLRAGFGINLESLRKVGMTAVKMSFIPDVFEGLAVMVASHYILGLPIIEAG---ILGFVI 124
Query: 116 TPTSVSITVKVLMEL--GKLRTKEG--ATILAAAVVDDVLGILILTIVISMLREGSVH-- 169
S ++ V ++ ++ T +G IL A VDDV+ I + ++ + + + V+
Sbjct: 125 AAVSPAVIVPQMLSFIERRMGTAKGIPTIILTGASVDDVVSITLFSVFLGIYQGQQVNLL 184
Query: 170 ---YDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLA 226
V + +L + G LA+ L L + R K + AI+ + ++
Sbjct: 185 VEAIGVPLSILTGITGGLALGLALVYLFRRFEIRNTEKTLI---ILGAAILLKNMGDLIS 241
Query: 227 EHLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPV-FFVEVGMRIDPRFLFEA 285
+L +A+++G ++GL I + + ++ IF + FV VG ++D R +F
Sbjct: 242 TYLPIAALVGVMVVGLVILERMPETGLKLSEKFNKVWIFAEILLFVLVGAQVDVRLIFHV 301
Query: 286 KTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGV- 344
++ + IG L + + + + IP+ V+ A+ + +AAGV
Sbjct: 302 GLLGLAVITAGLMVRSIGVLLSLKGTDLNLKEKVFCISAYIPKATVQAAIGAIPLAAGVA 361
Query: 345 AGSDVLTVAMTMVFLTTLITPIMLRKT 371
AG +L +A+ + T + + ++ T
Sbjct: 362 AGETILAMAVLAILFTAPLGSLAVKWT 388
>pir||F82595 glutathione-regulated potassium efflux system protein XF2140
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9107273|gb|AAF84939.1|AE004028_7 (AE004028)
cation:proton antiporter [Xylella fastidiosa]
Length = 572
Score = 73.7 bits (178), Expect = 3e-12
Identities = 89/393 (22%), Positives = 176/393 (44%), Gaps = 48/393 (12%)
Query: 6 MLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL----IERNEIIVEFANLGVLMLL 61
++A+ L++A + G + +R ++G ++AG+ +G + +I + + LGV++L+
Sbjct: 10 IIAVGLSLAFVLGALAQRLKLSPLVGYLVAGICVGPFTPGFVADQQIANQLSELGVMLLM 69
Query: 62 FLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMTPTSV 120
F GL E+ V +I A V + A L G+ +A+ + +++G ++ S
Sbjct: 70 FGVGLHFSLEDLLEVKAIAIPGALVQIAAATLLGWGLAWTMGWPMVQGVVFGLALSVAST 129
Query: 121 SITVKVLMELGKLRTKEGATILAAAVVDD---VLGILILTIVISMLR------------- 164
+ ++ L E + T+ G + +V+D VL +++L + ML
Sbjct: 130 VVLLRALEERRLIDTQRGRIAVGWLIVEDLVMVLALVLLPALAQMLNGNESVAAHTPNGS 189
Query: 165 -EGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFA 223
+G+ + LL++AGF+AV L +G V+ +++ E T + + A
Sbjct: 190 SDGNAMLTALGWTLLKMAGFVAVMLVVGRRVIPWSLEKVAATGSRELFTLAVLGIALGVA 249
Query: 224 Y-LAEHLNLASILGAYLIGLSI--GQTSYKKRIEG-PMNVIGYSIFIPVFFVEVGMRIDP 279
+ A+ ++ LGA+ G+ + +TS+ + P+ F +FFV VGM +P
Sbjct: 250 FGSAKLFGVSFALGAFFAGMVLKGSETSHAAATDSLPLR----DAFAVLFFVAVGMLFNP 305
Query: 280 RFLFEAKTFAFLYAVFAMISKVIGCGLGAYL--SKFDWRTSIKIGIG-----------MI 326
L E L + ++ IG A+L F TS + I ++
Sbjct: 306 AILIEHP----LQVLATFLTITIGKSAAAFLIVRAFGHPTSTALTISTSLAQIGEFSFIL 361
Query: 327 PRLGVELAMI-STAMAAGVAGSDVLTVAMTMVF 358
LG++LA++ T +AG+ + +A +F
Sbjct: 362 AGLGIQLAILPETGRDLILAGALLSIIANPFLF 394
>gb|AAD30610.1|AC007153_2 (AC007153) similar to Na/H antiporter proteins [Arabidopsis
thaliana]
Length = 855
Score = 73.4 bits (177), Expect = 4e-12
Identities = 80/385 (20%), Positives = 163/385 (41%), Gaps = 39/385 (10%)
Query: 11 LAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIE-----------------RNEIIVE-F 52
L VA LS V +P+ L +A ++ GLL R +++E F
Sbjct: 58 LFVANLSYRVLYYLTRPLYLPPFVAQILCGLLFSPSVLGNTRFIIAHVFPYRFTMVLETF 117
Query: 53 ANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFG-FLIAYPFFDFGTALLY 111
ANL ++ +FL GL D + +++A G+L A G FL P ++
Sbjct: 118 ANLALVYNIFLLGLGMDLRMVRITELKPVIIAFTGLLVALPVGAFLYYLPGNGHPDKIIS 177
Query: 112 GAIMTPTSVSIT-----VKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREG 166
G + +++ T ++L +L LR+ G T + AA+V D+ ++L + +
Sbjct: 178 GCVFWSVALACTNFPDLARILADLKLLRSDMGRTAMCAAIVTDLCTWVLLVFGFASFSKS 237
Query: 167 SVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLA 226
++ V++ A F+ + +++ + +F + K +VL +
Sbjct: 238 GTWNKMMPFVIITTAIFVLLCIFVIRPGIAWIFAKTVKAG-----------GVVLCGLIT 286
Query: 227 EHLNLASILGAYLIGLSIGQTS-YKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFL--F 283
+ + SI GA+L GLSI + IE ++ I +P+F++ G+R D F+ F
Sbjct: 287 DACGVHSITGAFLFGLSIPHDHIIRNMIEEKLHDFLSGILMPLFYIICGLRADIGFMLQF 346
Query: 284 EAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAG 343
K + + + K++ + + R + IG M + + L +++
Sbjct: 347 TDKFMMVVVICSSFLVKIVTTVITSLFMHIPMRDAFAIGALMNTKGTLSLVVLNAGRDTK 406
Query: 344 VAGSDVLT-VAMTMVFLTTLITPIM 367
S + T + + ++ ++ ++ P++
Sbjct: 407 ALDSPMYTHMTIALLVMSLVVEPLL 431
>pir||E82956 probable potassium efflux transporter PA5518 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9951855|gb|AAG08903.1|AE004964_6 (AE004964) probable
potassium efflux transporter [Pseudomonas aeruginosa]
Length = 567
Score = 73.0 bits (176), Expect = 5e-12
Identities = 82/324 (25%), Positives = 144/324 (44%), Gaps = 25/324 (7%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL----IERNEIIVEFANLGVLM 59
L LA +A L G + R ++G ++AGV+ G + + E A LGV++
Sbjct: 7 LTTLAAGFVLAFLFGALANRLRISPLVGYLLAGVLAGPFTPGYVADQALSQEIAELGVIL 66
Query: 60 LLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMTPT 118
L+F GL ++ V +I A V + A L G +A + FG L++G ++
Sbjct: 67 LMFGVGLHFSLKDLLSVKAIAIPGALVQIGVATLLGIGLAKLLGWSFGGGLVFGLSLSVA 126
Query: 119 SVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDV------ 172
S + ++ L + L TK G + +V+D+ ++LT+V+ G++
Sbjct: 127 STVVLLRALEQRQLLDTKRGRIAIGWLIVEDL--AMVLTLVLLPALAGTLGGKTDGGDAG 184
Query: 173 ----IVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAY-LAE 227
++ L +VA F+A+ ++ G V+ V R++ E T + + AY A
Sbjct: 185 LLWPLLITLGKVAAFVALMIFGGRRVVPWVLERIAASGSRELFTLAVLAIALGIAYGSAV 244
Query: 228 HLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGY-SIFIPVFFVEVGMRIDPRFLFEAK 286
++ LGA+ G+ + ++ E N + F +FFV VGM +P L +
Sbjct: 245 LFGVSFALGAFFAGMILNESELSH--EAAENSLPLRDAFAVLFFVSVGMLFNPMILLQEP 302
Query: 287 TFAFLYAVFAMISKVIGCGLGAYL 310
+ A F +I V G + AYL
Sbjct: 303 --LTVLATFLVI--VFGKSVAAYL 322
>pir||JC5342 Na+/H+ antiporter cdu2 - Clostridium difficile
>gi|1770129|emb|CAA63558.1| (X92982) cdu2 [Clostridium
difficile] >gi|1770130|emb|CAA63559.1| (X92982) cdu2
[Clostridium difficile]
Length = 313
Score = 71.8 bits (173), Expect = 1e-11
Identities = 71/302 (23%), Positives = 141/302 (46%), Gaps = 26/302 (8%)
Query: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERN--EIIVEFANLGV 57
L LAL+ + SG +F+R P +LG ++ G+I+G LI+ + +I + + +
Sbjct: 2 LTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNLIDNSILDISSDLRKIAL 61
Query: 58 LMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGTALLYGAIM-- 115
+++L AGL D + K+VGRP++L+ + F + G ++ P G ++L A+M
Sbjct: 62 IIILTRAGLSLDINDLKKVGRPAVLMCFIPATFE-IIGMIVLAPKL-LGVSILEAAVMGA 119
Query: 116 -----TPTSVSITVKVLMELGKLRTKE-GATILAAAVVDDVLGILILTIVISMLREGSVH 169
+P + + LME G K +LA +DD+ I++ T+ + + S+
Sbjct: 120 VVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDIFVIVMFTVFTGLAQGNSIS 179
Query: 170 YDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLV--LFAYLAE 227
+++ + + + +G + + F+++ D + +I FL+ L L
Sbjct: 180 AISFLQIPVSIILGVIAGAVIG-ICLAVFFKKVHMRDSAKGVLLLSISFLMISLETALEG 238
Query: 228 HLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYS-IFIP---VFFVEVGMRIDPRFLF 283
+ + +L IG+ + K R+ I YS +++ + FV VG +D + F
Sbjct: 239 IVPFSGLLAVMSIGIFL---QIKYRVVARRLSIKYSKLWVGAEILLFVLVGATVDISYAF 295
Query: 284 EA 285
+A
Sbjct: 296 KA 297
>pir||T35102 probable transmembrane transport protein - Streptomyces coelicolor
>gi|2995290|emb|CAA18319.1| (AL022268) putative
transmembrane transport protein [Streptomyces coelicolor
A3(2)]
Length = 411
Score = 71.8 bits (173), Expect = 1e-11
Identities = 80/337 (23%), Positives = 152/337 (44%), Gaps = 29/337 (8%)
Query: 47 EIIVEFANLGVLMLLFLAGLE---SDFEEFKRVGRPSILV-----ASVGVLFAFLFGFLI 98
E + A +GV++LL + GLE SD + P+ LV A G + A L G+
Sbjct: 55 EFVATGAEIGVILLLLMLGLEYTASDLVTNLKSHYPAGLVDCALNAVPGAVAALLMGWGP 114
Query: 99 AYPFFDFGTALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTI 158
A++ + +S + KVL +LG++ +E IL+ V++D+ + L I
Sbjct: 115 V-------AAVVLAGVTWISSSGVIAKVLGDLGRVGNRETPVILSVLVLEDLAMAVYLPI 167
Query: 159 VISMLR-EGSVHYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIV 217
V +++ G + + + V L AG L +F+ V + R D PE +
Sbjct: 168 VTALVAGAGLMTGSITLAVALAAAG-LVLFV---AVRYGRLISRFVSSDDPEKLLLVVLG 223
Query: 218 FLVLFAYLAEHLNLASILGAYLIGLSI-GQTSYKKRIEGPMNVIG--YSIFIPVFFVEVG 274
+L A +A+ L +++ +GA+L+G+++ G+ + EG ++ +F VFFV G
Sbjct: 224 LTILVAGVAQQLQVSAAVGAFLVGIALSGEVA-----EGAHTLLSPLRDLFAAVFFVFFG 278
Query: 275 MRIDPRFLFEAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELA 334
+ DP + A A+ ++K+ A + + + G ++ R +
Sbjct: 279 LHTDPASIPPVLLPALALALLTAVTKIATGYWAARRAGISVKGRWRAGGALVARGEFSIV 338
Query: 335 MISTAMAAGVAGSDVLTVAMTMVFLTTLITPIMLRKT 371
+ A++AG+ S + +A V + ++ P+ R T
Sbjct: 339 IAGLAVSAGIEPS-LGPLATAYVLILVVLGPLTARFT 374
>gb|AAC60780.1| (U46859) RosB [Yersinia enterocolitica (type 0:8)]
Length = 563
Score = 70.2 bits (169), Expect = 4e-11
Identities = 77/375 (20%), Positives = 158/375 (41%), Gaps = 25/375 (6%)
Query: 11 LAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL----IERNEIIVEFANLGVLMLLFLAGL 66
L +A L G + R ++G + AGV+ G + + E A +GV++L+F GL
Sbjct: 15 LVLAFLLGSLAHRLRSSPLVGYLAAGVLAGPFTPGFVADTSLAPELAEIGVILLMFGVGL 74
Query: 67 ESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMTPTSVSITVK 125
++ V +I A + A L G +++ +D T ++G ++ S + ++
Sbjct: 75 HFSLKDLLAVKAIAIPGAVAQIAVATLLGMGLSHLLGWDLMTGFVFGLCLSTASTVVLLR 134
Query: 126 VLMELGKLRTKEGATILAAAVVDDVLGILILTIVIS----MLREGSVHYDVIVEVLL--- 178
L E + ++ G + ++V+D+ +L L ++ + M E + + E+ +
Sbjct: 135 ALEERQLIDSQRGQIAIGRSIVEDLAMVLTLVLLPAFAGVMGNETTSLSQLFTELAITIG 194
Query: 179 EVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHL-NLASILGA 237
+V F+ + + +G ++ + + + E T +V + AY A L +++ LGA
Sbjct: 195 KVIAFITLMIVVGRRLVPWILAKTASTGSRELFTLAVLVLALGIAYGAVGLFDVSFALGA 254
Query: 238 YLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAK----------T 287
+ G+ + ++ R + F +FFV VGM DP L
Sbjct: 255 FFAGMVLNESELSHRAAQDTLPL-RDAFAVLFFVSVGMLFDPMILLREPLAVLASLAIII 313
Query: 288 FAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGS 347
F A F ++ + + WR S+ + ++ LG+ L ++S V
Sbjct: 314 FGKSAAAFILVRMFGHSNVYSTHHFCPWRKSVNLPF-ILAGLGISLGLMSEHGRNLVLAG 372
Query: 348 DVLTVAMTMVFLTTL 362
+L++ + + T L
Sbjct: 373 AILSIMLNPLLFTLL 387
>dbj|BAB07757.1| (AP001520) Na+/H+ antiporter [Bacillus halodurans]
Length = 490
Score = 70.2 bits (169), Expect = 4e-11
Identities = 82/383 (21%), Positives = 174/383 (45%), Gaps = 30/383 (7%)
Query: 2 ETLLMLA-LMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANL- 55
+T+++LA L+ V ++ R P ++ I+ G+++G LI + FA L
Sbjct: 6 DTIILLAGLLFIVGVITAKFSTRLGVPALVLFILVGMLVGSDGLGLIHFDFSQAHFAQLI 65
Query: 56 ---GVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLF-----AFLFGFLIAYPFFDFGT 107
++++LF GL++ ++ + V PS+ +A+ GVL A +++ + +
Sbjct: 66 GIFALVIILFEGGLQTKWKTVQSVAVPSLSLATFGVLITSTLVAVAAKYVLGVSWLE--- 122
Query: 108 ALLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGS 167
A L+GAI+ T + VL E ++ + T+ A + +D + + + +I ++ GS
Sbjct: 123 AYLFGAIVGSTDAAAVFAVLKE-QNIKDRLATTLEAESGTNDPMAVFLTLSLIELITIGS 181
Query: 168 VH-YDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPES--TTSFAIVFLVLFAY 224
++ + L ++ L + LG + ++ +K++L S FA+ F +L
Sbjct: 182 MNPLHLFGSFLWQMGAGLILGFGLGKLGSYSI----NKINLDSSGLYPVFALAFALLTYS 237
Query: 225 LAEHLNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIP-VFFVEVGMRIDPRFLF 283
+ + + +L Y+ L IG R G++ + + F+ +G+ + P LF
Sbjct: 238 VTAMIGASGLLAVYVAALVIGNQDLTYRHSIFRFNEGFAWMMQMLMFIILGLLVFPNQLF 297
Query: 284 EAKTF---AFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAM 340
EA F L + ++++ + L +FDW+ + + + R V + + + M
Sbjct: 298 EASIFIKGILLSLILMLVARPVAVFLTTIKMRFDWKEKLFLSWAGL-RGAVPIVLATFPM 356
Query: 341 AAGVAGSDVLTVAMTMVFLTTLI 363
AG+ S + + V LT+ +
Sbjct: 357 TAGLENSPLFFNVVFFVVLTSAL 379
>gb|AAA84962.1| (U37008) KefC [Myxococcus xanthus]
Length = 598
Score = 69.9 bits (168), Expect = 5e-11
Identities = 67/298 (22%), Positives = 127/298 (42%), Gaps = 12/298 (4%)
Query: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERNEIIVEFANLG 56
M L + LA L+ + R VLG + G ++G LI E I A LG
Sbjct: 1 MSFLQQALVFLAAVVLADPLSRRLGLGSVLGYLAGGAVIGPWGLKLISDVEHIFHVAELG 60
Query: 57 VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIA----YPFFDFGTALLYG 112
V++LL LE + R + VLF G L+A +G A++ G
Sbjct: 61 VVVLLLFVSLELQTSRLWALRRSVFGLGGAQVLFT---GALLASVGLLCSLTWGAAIVTG 117
Query: 113 AIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDV 172
++ +S + +++L+E +L T G + D+ + +L ++ + G+
Sbjct: 118 FGLSLSSTAFALQLLVERNRLTTPYGQLAFGILLFQDLAVVPLLALLPLLGDGGAPSPGT 177
Query: 173 IVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLA 232
+ +LL+ G L + G ++ FR ++ E T+ A++ +V A + + L+
Sbjct: 178 VWLLLLKDVGVLLAEVLSGRYLVRPAFRAVAATHRQELFTATALLLVVATASVINAVGLS 237
Query: 233 SILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAF 290
L A L G+ + + Y+ +E + + + +FF+ VGM ++ + + F
Sbjct: 238 MGLAASLAGVLLADSEYRHELEADLAPF-KGLLMGLFFISVGMTVNLSLILQKPLLVF 294
>pir||H71848 probable na+/h+ antiporter - Helicobacter pylori (strain J99)
>gi|4155698|gb|AAD06681.1| (AE001538) putative NA+/H+
ANTIPORTER [Helicobacter pylori J99]
Length = 383
Score = 69.1 bits (166), Expect = 8e-11
Identities = 75/294 (25%), Positives = 135/294 (45%), Gaps = 32/294 (10%)
Query: 8 ALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLL--IERNEIIVEFANLGVLMLLFLAG 65
AL++ + ++ +V PI + +I+ G + + IE + + +G L L+FL G
Sbjct: 9 ALIMLLIVIAPYVSRISRLPITVVEILFGSVGAYVGFIEPTKGFEIMSEIGFLFLMFLCG 68
Query: 66 LESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPF-FDFGTALLYGAIMTPTSVSITV 124
LE + FK++G V+ + +FA+L LI Y F +L I I++
Sbjct: 69 LEVEIYLFKKLG-----VSLLKRIFAYL---LILYTLSFILTFSLNLEPIFMVIFPIISL 120
Query: 125 KVLMELGKLRTKEGA---TILAAAVVDDVLGILILTIVISMLREGSVHYDVIVEVLLEVA 181
++M L K KE +L V+ ++L I L +V + G + D+I ++
Sbjct: 121 GMIMTLVKDYRKEILWLDLVLKVGVIGELLSIFGLVVVDGVYSHG-LGVDLIKDL----- 174
Query: 182 GFLAVFLYLGPVVMENV------FRRLSKVDLPEST-----TSFAIVFLVLFAYLAEHLN 230
G L VFL L V + F L +P+S+ F+++ + L
Sbjct: 175 GILIVFLILIIVAFQIFKTLFWWFPHLKLFVMPKSSQFNQDVRFSLMLFFSLVAIVVWLK 234
Query: 231 LASILGAYLIGLSIGQT-SYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLF 283
+ +LGA+L GL + +K + +N +G+ F+P+FF+ VG +D + +F
Sbjct: 235 IEMVLGAFLAGLVVSTFFPHKSELIHKLNDVGFGFFVPLFFIHVGSTLDLKLVF 288
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.331 0.146 0.413
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 116044066
Number of Sequences: 2977
Number of extensions: 4538859
Number of successful extensions: 17500
Number of sequences better than 1.0e-10: 76
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 17264
Number of HSP's gapped (non-prelim): 91
length of query: 375
length of database: 189,106,746
effective HSP length: 55
effective length of query: 320
effective length of database: 156,189,961
effective search space: 49980787520
effective search space used: 49980787520
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.9 bits)
S2: 166 (69.1 bits)