BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0139 (lysS) DE:lysyl-tRNA synthetase (lysS)
         (526 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

sp|Q9V270|SYK_PYRAB LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...  1097  0.0
sp|O57963|SYK_PYRHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   965  0.0
sp|O83650|SYK_TREPA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   402  e-111
pir||C64367 hypothetical protein MJ0539 - Methanococcus jannaschii    382  e-105
sp|Q57959|SYK_METJA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   381  e-104
sp|O51603|SYK_BORBU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   380  e-104
sp|O30522|SYK_METMP LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   353  4e-96
gi|11498815 lysyl-tRNA synthetase (lysS) [Archaeoglobus fulgidus...   333  3e-90
sp|O27585|SYK_METTH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   332  8e-90
sp|P57677|SYK_THEAC LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   298  8e-80
gb|AAG20183.1| (AE005095) lysyl-tRNA synthetase; LysS [Halobacte...   267  2e-70
sp|Q9X895|SYK_STRCO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   252  5e-66
sp|Q9YFT9|SYK_AERPE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   229  8e-59
sp|O74059|SYK_CERSY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   186  6e-46
sp|Q9ZDF8|SYK_RICPR LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   150  3e-35

>sp|Q9V270|SYK_PYRAB LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7450808|pir||A75210 lysyl-tRNA synthetase (lyss)
           PAB0139 - Pyrococcus abyssi  (strain Orsay)
           >gi|5457637|emb|CAB49128.1| (AJ248283) lysyl-tRNA
           synthetase (lysS) [Pyrococcus abyssi]
           Length = 526
           
 Score = 1097 bits (2807), Expect = 0.0
 Identities = 526/526 (100%), Positives = 526/526 (100%)

Query: 1   MVIVVHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGY 60
           MVIVVHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGY
Sbjct: 1   MVIVVHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGY 60

Query: 61  EVRHIHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKE 120
           EVRHIHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKE
Sbjct: 61  EVRHIHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKE 120

Query: 121 LGIEVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYC 180
           LGIEVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYC
Sbjct: 121 LGIEVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYC 180

Query: 181 PEHRKEAEIIEWDGEWKVKYRCPEGHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAG 240
           PEHRKEAEIIEWDGEWKVKYRCPEGHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAG
Sbjct: 181 PEHRKEAEIIEWDGEWKVKYRCPEGHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAG 240

Query: 241 KDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVL 300
           KDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVL
Sbjct: 241 KDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVL 300

Query: 301 EPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEELKRTYELS 360
           EPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEELKRTYELS
Sbjct: 301 EPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEELKRTYELS 360

Query: 361 NPRIPNRLIAQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDIERIRLRIRLA 420
           NPRIPNRLIAQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDIERIRLRIRLA
Sbjct: 361 NPRIPNRLIAQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDIERIRLRIRLA 420

Query: 421 KNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESKSTFSVDELNNVLFEVAK 480
           KNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESKSTFSVDELNNVLFEVAK
Sbjct: 421 KNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESKSTFSVDELNNVLFEVAK 480

Query: 481 KRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRRLRLEG 526
           KRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRRLRLEG
Sbjct: 481 KRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRRLRLEG 526


>sp|O57963|SYK_PYRHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7450803|pir||A71246 lysine--tRNA ligase (EC 6.1.1.6)
           - Pyrococcus horikoshii >gi|3256613|dbj|BAA29296.1|
           (AP000001) 523aa long hypothetical lysyl-tRNA synthetase
           [Pyrococcus horikoshii]
           Length = 523
           
 Score =  965 bits (2467), Expect = 0.0
 Identities = 440/523 (84%), Positives = 492/523 (93%)

Query: 4   VVHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVR 63
           +VHWADY+ADKIIRERGEK++YVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVR
Sbjct: 1   MVHWADYIADKIIRERGEKEKYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVR 60

Query: 64  HIHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELGI 123
           HIHMWDDYDRFRKVPRNVP EWK+YLGMP+SEVPDPWGCH+SYAEHFM KFE EV++LGI
Sbjct: 61  HIHMWDDYDRFRKVPRNVPQEWKDYLGMPISEVPDPWGCHESYAEHFMRKFEEEVEKLGI 120

Query: 124 EVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYCPEH 183
           EV+FLYASELYKRGEYSEEIR AFE ++KIMEILNKYREIAKQPPLPENWWPAMVYCPEH
Sbjct: 121 EVDFLYASELYKRGEYSEEIRLAFEKRDKIMEILNKYREIAKQPPLPENWWPAMVYCPEH 180

Query: 184 RKEAEIIEWDGEWKVKYRCPEGHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAGKDH 243
           R+EAEIIEWDG WKVKY+CPEGHEGWVDIRSGNVKLRWRVDWPMRW+HF VDFEPAGKDH
Sbjct: 181 RREAEIIEWDGGWKVKYKCPEGHEGWVDIRSGNVKLRWRVDWPMRWSHFGVDFEPAGKDH 240

Query: 244 LAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVLEPG 303
           L AGSSYDTGKEIIK +YGKEAP+SLMYEFVGIKG+KGKMSGSKGNVILLSDLYEVLEPG
Sbjct: 241 LVAGSSYDTGKEIIKEVYGKEAPLSLMYEFVGIKGQKGKMSGSKGNVILLSDLYEVLEPG 300

Query: 304 LVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEELKRTYELSNPR 363
           LVRFIYARHRPNKEI+IDLG+G+LNLYDEFDKVERIYFGVE  KGD EEL+RTYELS P+
Sbjct: 301 LVRFIYARHRPNKEIKIDLGLGILNLYDEFDKVERIYFGVEGGKGDDEELRRTYELSMPK 360

Query: 364 IPNRLIAQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDIERIRLRIRLAKNW 423
            P RL+AQAPFRFLAVLVQ+PHL E+ II+VL  QGH+P++L +ED+ER++LRI LA+NW
Sbjct: 361 KPERLVAQAPFRFLAVLVQLPHLTEEDIINVLIKQGHIPRDLSKEDVERVKLRINLARNW 420

Query: 424 VEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESKSTFSVDELNNVLFEVAKKRG 483
           V+KYAP+ VKFSIL +PP++E+ E VREAM EVA+W+E+   FSV+E NN+LFEVAK+RG
Sbjct: 421 VKKYAPEDVKFSILEKPPEVEVSEDVREAMNEVAEWLENHEEFSVEEFNNILFEVAKRRG 480

Query: 484 ISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRRLRLEG 526
           ISS+EWFSTLY+LFIGKERGPRLASFLASLD+ FV++RLRLEG
Sbjct: 481 ISSREWFSTLYRLFIGKERGPRLASFLASLDRSFVIKRLRLEG 523


>sp|O83650|SYK_TREPA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7450805|pir||C71299 lysine--tRNA ligase (EC 6.1.1.6)
           (lysS-1) - syphilis spirochete
           >gi|3322943|gb|AAC65618.1| (AE001239) lysyl-tRNA
           synthetase (lysS-1) [Treponema pallidum]
           Length = 528
           
 Score =  402 bits (1022), Expect = e-111
 Identities = 208/515 (40%), Positives = 317/515 (61%), Gaps = 18/515 (3%)

Query: 5   VHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRH 64
           +HWAD VA KII+ER + D+Y   SGITPSG VH+GNFRE+ +  +V  ALRD+G  VR 
Sbjct: 8   LHWADKVAHKIIKERADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRDQGKSVRF 67

Query: 65  IHMWDDYDRFRKVPRNVPP--EWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELG 122
           +H WDDYD FR++P NVP   E K+Y+ MP++ VPDP+   DSYA H   + E  + E+G
Sbjct: 68  VHSWDDYDVFRRIPDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIESALPEVG 127

Query: 123 IEVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYCPE 182
           I  E++Y S+ Y+ G Y++EI+ A + + +I  ILN+YR+  +Q  +   +WP  V+C  
Sbjct: 128 IYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQAILNEYRD--EQHKISGTYWPVSVFCTA 185

Query: 183 HRKEAEIIE-WDGEWKVKYRCPEGHEGWVDIRSGN-VKLRWRVDWPMRWAHFDVDFEPAG 240
             K+   ++ WD  W ++Y C  GH   VD+R  + VKL WRVDW MRW+   V FEPAG
Sbjct: 186 CHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVVFEPAG 245

Query: 241 KDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVL 300
           KDH + G S+DT + I   IY   AP+S  Y+F+G+KG  GKMS S G V+ L D+ EV 
Sbjct: 246 KDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRDVLEVY 305

Query: 301 EPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEEL--KRTYE 358
           +P ++R+++   RPN E  I   + +L +Y+++DK ER+ +G+  AK + E +  KR YE
Sbjct: 306 QPEVLRYLFVSTRPNTEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRHKRIYE 365

Query: 359 LSNPR-IPNRLIAQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDIERIRLRI 417
           LS  R +P  +  Q PFR +  ++Q+   D   +++  +       ++ ++ IER   R 
Sbjct: 366 LSQVRGMPPCISYQVPFRHVCNILQINSGDISAVLAFFS-------DIHKDQIERFVRRC 418

Query: 418 RLAKNWV-EKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESKS-TFSVDELNNVL 475
           + A NW+ +  APD  KF++  +  ++ +   + EA+  +   +  ++   S  EL+  L
Sbjct: 419 QCAWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAEL 478

Query: 476 FEVAKKRGISSKEWFSTLYKLFIGKERGPRLASFL 510
           + VA++  + SKE F+ LY++ IGK +GPRLA F+
Sbjct: 479 YAVARQIPVGSKELFTALYQVLIGKNQGPRLAGFM 513


>pir||C64367 hypothetical protein MJ0539 - Methanococcus jannaschii
           Length = 534
           
 Score =  382 bits (971), Expect = e-105
 Identities = 208/538 (38%), Positives = 321/538 (59%), Gaps = 26/538 (4%)

Query: 4   VVHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVR 63
           ++HWAD +A+K+I ER + D+Y+V SGITPSG++HVGN RE  TA  +   L +KG E  
Sbjct: 4   IMHWADVIAEKLIEER-KADKYIVASGITPSGHIHVGNARETLTADAIYKGLINKGVEAE 62

Query: 64  HIHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELGI 123
            I + D YD  RK+   +P E+++Y+GMP+SE+P P GC +SYAEHF+  +   + +LG+
Sbjct: 63  LIFIADTYDPLRKLYPFLPKEFEQYIGMPLSEIPCPEGCCESYAEHFLRPYLESLDDLGV 122

Query: 124 EVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYCPEH 183
           E+    A E YK+G Y E+I+ A + +EKIMEILNK+R      PLP++WWP  + C   
Sbjct: 123 ELTTYRADENYKKGLYDEKIKIALDNREKIMEILNKFR----ANPLPDDWWPINIVCENC 178

Query: 184 RK-EAEIIEWDGE-WKVKYRCPE-GHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAG 240
            K + ++I++D E  ++ YRC   G E  V    G  KL WRVDWP RW+ F+V  EP G
Sbjct: 179 GKLKTKVIKYDSEKEEITYRCEICGFENTVKPYKGRAKLPWRVDWPARWSIFNVTIEPMG 238

Query: 241 KDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIK-GEKG-KMSGSKGNVILLSDLYE 298
           KDH AAG SYDTG  I K IY    P  ++YE++ +K G+K   MS SKG V  + D   
Sbjct: 239 KDHAAAGGSYDTGVLIAKEIYNYIPPKKVVYEWIQLKVGDKAIPMSSSKGVVFAVKDWTN 298

Query: 299 VLEPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVED---AKGDVEELKR 355
           +  P ++RF+  R +P K I  DL   + +L DE+D++E  YF  +D      + +E  R
Sbjct: 299 IAHPEILRFLLLRSKPTKHIDFDL-KKIPDLVDEYDRLEDFYFNNKDKDELSEEEQEKIR 357

Query: 356 TYELSNPRIPNRLIAQAPFRFLAVLVQMPHLDE------DGIISVLTNQGHVPKELERED 409
            YELS P+IP       P+RF +++ Q+ + +E      + +  +L    +   +++   
Sbjct: 358 IYELSTPKIPETKPFVIPYRFCSIIAQLTYDEEKEDINMERVFEILRRNNYSIDDIDEFS 417

Query: 410 IERIRLRIRLAKNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESK---STF 466
           +++++ R+ +A+NW  KY     K  I+ E    EI E +++  +E  K+   K   + F
Sbjct: 418 MKKLKDRLLMARNWALKYGE---KLVIISEDEAKEIYEKLKDKQKEWIKYFAEKLKTAEF 474

Query: 467 SVDELNNVLFEVAKKRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRRLRL 524
               L+ ++++ AK+ G++ ++ F   Y + +GK+ GP+L +FLA+L KDFV+RR  L
Sbjct: 475 DALNLHELIYQTAKELGLNPRDAFQASYMILLGKKYGPKLGAFLATLGKDFVIRRYSL 532


>sp|Q57959|SYK_METJA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|2826296|gb|AAB98532.1| (U67503) tRNA synthetase,
           putative [Methanococcus jannaschii]
           Length = 530
           
 Score =  381 bits (968), Expect = e-104
 Identities = 208/537 (38%), Positives = 320/537 (58%), Gaps = 26/537 (4%)

Query: 5   VHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRH 64
           +HWAD +A+K+I ER + D+Y+V SGITPSG++HVGN RE  TA  +   L +KG E   
Sbjct: 1   MHWADVIAEKLIEER-KADKYIVASGITPSGHIHVGNARETLTADAIYKGLINKGVEAEL 59

Query: 65  IHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELGIE 124
           I + D YD  RK+   +P E+++Y+GMP+SE+P P GC +SYAEHF+  +   + +LG+E
Sbjct: 60  IFIADTYDPLRKLYPFLPKEFEQYIGMPLSEIPCPEGCCESYAEHFLRPYLESLDDLGVE 119

Query: 125 VEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYCPEHR 184
           +    A E YK+G Y E+I+ A + +EKIMEILNK+R      PLP++WWP  + C    
Sbjct: 120 LTTYRADENYKKGLYDEKIKIALDNREKIMEILNKFR----ANPLPDDWWPINIVCENCG 175

Query: 185 K-EAEIIEWDGE-WKVKYRCPE-GHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAGK 241
           K + ++I++D E  ++ YRC   G E  V    G  KL WRVDWP RW+ F+V  EP GK
Sbjct: 176 KLKTKVIKYDSEKEEITYRCEICGFENTVKPYKGRAKLPWRVDWPARWSIFNVTIEPMGK 235

Query: 242 DHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIK-GEKG-KMSGSKGNVILLSDLYEV 299
           DH AAG SYDTG  I K IY    P  ++YE++ +K G+K   MS SKG V  + D   +
Sbjct: 236 DHAAAGGSYDTGVLIAKEIYNYIPPKKVVYEWIQLKVGDKAIPMSSSKGVVFAVKDWTNI 295

Query: 300 LEPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVED---AKGDVEELKRT 356
             P ++RF+  R +P K I  DL   + +L DE+D++E  YF  +D      + +E  R 
Sbjct: 296 AHPEILRFLLLRSKPTKHIDFDL-KKIPDLVDEYDRLEDFYFNNKDKDELSEEEQEKIRI 354

Query: 357 YELSNPRIPNRLIAQAPFRFLAVLVQMPHLDE------DGIISVLTNQGHVPKELEREDI 410
           YELS P+IP       P+RF +++ Q+ + +E      + +  +L    +   +++   +
Sbjct: 355 YELSTPKIPETKPFVIPYRFCSIIAQLTYDEEKEDINMERVFEILRRNNYSIDDIDEFSM 414

Query: 411 ERIRLRIRLAKNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESK---STFS 467
           ++++ R+ +A+NW  KY     K  I+ E    EI E +++  +E  K+   K   + F 
Sbjct: 415 KKLKDRLLMARNWALKYGE---KLVIISEDEAKEIYEKLKDKQKEWIKYFAEKLKTAEFD 471

Query: 468 VDELNNVLFEVAKKRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRRLRL 524
              L+ ++++ AK+ G++ ++ F   Y + +GK+ GP+L +FLA+L KDFV+RR  L
Sbjct: 472 ALNLHELIYQTAKELGLNPRDAFQASYMILLGKKYGPKLGAFLATLGKDFVIRRYSL 528


>sp|O51603|SYK_BORBU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7450804|pir||B70182 lysine--tRNA ligase (EC 6.1.1.6)
           - Lyme disease spirochete >gi|2688588|gb|AAC67006.1|
           (AE001167) lysyl-tRNA synthetase [Borrelia burgdorferi]
           Length = 521
           
 Score =  380 bits (965), Expect = e-104
 Identities = 201/521 (38%), Positives = 319/521 (60%), Gaps = 24/521 (4%)

Query: 6   HWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRHI 65
           HWAD+ A+KI +E+G K+ Y V SGITPSG VH+GNFRE+ +  +V  ALRD G +VR I
Sbjct: 5   HWADFYAEKIKKEKGPKNLYTVASGITPSGTVHIGNFREVISVDLVARALRDSGSKVRFI 64

Query: 66  HMWDDYDRFRKVPRNVPPE--WKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELGI 123
           + WD+YD FRKVP+N+P +     YL   ++ VPD      SYA     +FE+ +  +GI
Sbjct: 65  YSWDNYDVFRKVPKNMPEQELLTTYLRQAITRVPDTRSHKTSYARANEIEFEKYLPVVGI 124

Query: 124 EVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYCPE- 182
             EF+  S+ Y    Y+ +I+ A + K+++ E LN+YR       L ENW+P  V+C + 
Sbjct: 125 NPEFIDQSKQYTSNAYASQIKFALDHKKELSEALNEYR----TSKLEENWYPISVFCTKC 180

Query: 183 HRKEAEIIEWDGEWKVKYRCPEGHEGWVDIR-SGNVKLRWRVDWPMRWAHFDVDFEPAGK 241
           +R    +  +D  + V+Y C  G++  +DIR +  +KL WR+DWPMRW +  VDFEPAGK
Sbjct: 181 NRDTTTVNNYDNHYSVEYSCECGNQESLDIRTTWAIKLPWRIDWPMRWKYEKVDFEPAGK 240

Query: 242 DHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVLE 301
           DH ++G S+DT K I+K   G   P++  Y+F+ IKG  GK+S S G+VI L D+ EV  
Sbjct: 241 DHHSSGGSFDTSKNIVKIFQG-SPPVTFQYDFISIKGRGGKISSSSGDVISLKDVLEVYT 299

Query: 302 PGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEE-LKRTYELS 360
           P + RF++A  +PN E  I   + ++ +Y+++DK ERIY+GVED K + +   KR YELS
Sbjct: 300 PEVTRFLFAATKPNTEFSISFDLDVIKIYEDYDKFERIYYGVEDVKEEKKRAFKRIYELS 359

Query: 361 NPRIPNRLIA-QAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDIERIRLRIRL 419
            P +P++ I  Q  FR L+V+ Q+   + + I++ L       K ++ +  +++  +I  
Sbjct: 360 QPYMPSKRIPYQVGFRHLSVISQIFENNINKILNYL-------KNVQEDQKDKLINKINC 412

Query: 420 AKNWVEKYAPDSVKFSILPEPPKIEI-DESVREAMEEVAKWIESKSTFSV---DELNNVL 475
           A NW+  +AP+  KFS+  +   +EI +E+ ++A+ E+  ++  K  F V    ++ N +
Sbjct: 413 AINWIRDFAPEDFKFSLRSKFDNMEILEENSKKAINELLDFL--KKNFEVATEQDIQNEI 470

Query: 476 FEVAKKRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKD 516
           ++++++  I    +F  +YK+ I KE+GP+LA F+  +  D
Sbjct: 471 YKISRENNIEPALFFKQIYKILIDKEKGPKLAGFIKIIGID 511


>sp|O30522|SYK_METMP LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|11280297|pir||T46975 lysine--tRNA ligase (EC
           6.1.1.6) [validated] - Methanococcus maripaludis
           >gi|2645489|gb|AAB87410.1| (AF009824) lysyl-tRNA
           synthetase [Methanococcus maripaludis]
           Length = 533
           
 Score =  353 bits (895), Expect = 4e-96
 Identities = 201/543 (37%), Positives = 304/543 (55%), Gaps = 35/543 (6%)

Query: 5   VHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRH 64
           +HWAD  ++KI+++R  ++ YVV SGITPSG++H+GN RE  TA  V   +  KG E + 
Sbjct: 1   MHWADATSEKIMKKRNAEE-YVVSSGITPSGHIHIGNARETLTADAVYKGMLKKGAEAKL 59

Query: 65  IHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELGIE 124
           I + DDYD  RK+   +P E+++Y+GMP+SE+P P GC  SYA+HF+  F   +++LG+E
Sbjct: 60  IFIADDYDPLRKLYPFLPKEFEKYIGMPLSEIPCPQGCCKSYADHFLMPFLNSLEDLGVE 119

Query: 125 VEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYCPEHR 184
           +    A+E YK G Y+E I  A E + KI E+L+ YR    + PL +NW+P  V C +  
Sbjct: 120 ITTHRANECYKAGMYNEAIITALENRLKIKELLDSYR----KEPLADNWYPLNVVCEKCG 175

Query: 185 K--EAEIIEWDGEWK-VKYRCPEGHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAGK 241
           K  E ++  ++ E K + Y C  G E  V   +G  KL WRVDWP RW  F V  EP GK
Sbjct: 176 KMHETKVTSYNSEDKTITYVCKCGFENTVQPFNGIGKLPWRVDWPARWNIFGVTAEPMGK 235

Query: 242 DHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIK-GEKG-KMSGSKGNVILLSDLYEV 299
           DH A+G SYDTG +I + I+  +AP  ++YE++ +K G+K   MS S G V  + D  E+
Sbjct: 236 DHAASGGSYDTGIKIARQIFNYQAPEKMVYEWIQLKIGDKAMPMSSSSGVVFAVKDWTEI 295

Query: 300 LEPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGV------EDAKGDVEEL 353
             P ++RF+  + +P K I  DL   + NL D++D++ER YF +      E+   +  E 
Sbjct: 296 CHPEVLRFLILKGKPTKHIDFDL-KAISNLVDDYDELERKYFELIEKQKTEELNDNENEK 354

Query: 354 KRTYELSNPRIPNRLIAQAPFRFLAVLVQM------PHLDEDGIISVLTNQGHVPKELER 407
              YEL  P+IP RL  Q  +RF +++ Q+        +D + +  +L   G+ P E   
Sbjct: 355 ISLYELVTPKIPERLPLQVAYRFCSIIAQIALDKETQKIDMERVFDILGRNGYNPAEFSE 414

Query: 408 EDIERIRLRIRLAKNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESKS--- 464
            D  R+  R+ ++K W   Y  +      L      +  E      EE   W+++ S   
Sbjct: 415 YDKSRLEKRLYMSKKWASDYGEN------LEINDFEQAKEQYETLSEEQKAWLKAFSKEV 468

Query: 465 ---TFSVDELNNVLFEVAKKRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRR 521
                  + ++ +++E A K  ++ KE F   YK+ +GK  GP+L SFLASL K+FV+ R
Sbjct: 469 ENIEIDANTIHELMYETATKLNLAPKEAFVASYKILLGKNYGPKLGSFLASLKKEFVIGR 528

Query: 522 LRL 524
             L
Sbjct: 529 FNL 531


>gi|11498815 lysyl-tRNA synthetase (lysS) [Archaeoglobus fulgidus]
           >gi|3183169|sp|O29052|SYK_ARCFU LYSYL-TRNA SYNTHETASE
           (LYSINE--TRNA LIGASE) (LYSRS) >gi|7450807|pir||G69401
           lysyl-tRNA synthetase (lysS) homolog - Archaeoglobus
           fulgidus >gi|2649372|gb|AAB90029.1| (AE001020)
           lysyl-tRNA synthetase (lysS) [Archaeoglobus fulgidus]
           Length = 493
           
 Score =  333 bits (845), Expect = 3e-90
 Identities = 183/521 (35%), Positives = 296/521 (56%), Gaps = 33/521 (6%)

Query: 5   VHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRH 64
           +HWAD +A  +++     + + + +GI+PSG++H+GN RE+ TA  +  AL D G E + 
Sbjct: 1   MHWADVIAADLLKR---SNSHRIATGISPSGHIHLGNLREMVTADAIRRALLDAGGEAKI 57

Query: 65  IHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELGIE 124
           +++ DD+D  R+    +P E++ Y+GMP+ ++PDP GCHDSY+EHF++ F   ++ LGI 
Sbjct: 58  VYIADDFDPLRRRYPFLPEEYENYVGMPLCKIPDPEGCHDSYSEHFLQPFLESLEILGIP 117

Query: 125 VEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYCPE-- 182
           VE   A ++Y  G Y    R A + +++I  I+    E+  +  L E W+P M  C    
Sbjct: 118 VEVRRAYQMYSEGLYENNTRIALKRRDEIARII---AEVTGR-ELEERWYPFMPLCENCG 173

Query: 183 HRKEAEIIEWDGEWKVKYRCPEGHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAGKD 242
                 +  +D  W + Y C  GH G V    G  KL WRVDW  RW    +  EP GKD
Sbjct: 174 RINSTRVTSFDENW-IYYECDCGHSGRVGYVGGG-KLTWRVDWAARWQILSITCEPFGKD 231

Query: 243 HLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVLEP 302
           H AAG SYDTG  I + I+  E P  + YE++ +KG KG M  SKG V+ + ++ EV+ P
Sbjct: 232 HAAAGGSYDTGVRIAREIFDYEPPYPVPYEWIHLKG-KGAMKSSKGIVLPVREMVEVIPP 290

Query: 303 GLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEELKRTYELSNP 362
            +VR+I  R +P + I  D G+GLL+L +EF++               +E  R+ ELS  
Sbjct: 291 EIVRYITIRVKPERHIEFDPGLGLLDLVEEFEE-------------KFKEKDRSVELS-- 335

Query: 363 RIPNRLIAQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDIERIRLRIRLAKN 422
            +   + +  PFR L V+ Q+ + D +  + ++   G+   ++ R D+ER   R++ A+ 
Sbjct: 336 LVGEVVYSDVPFRHLIVVGQIANWDLEKALEIIERTGYTVDDVTRRDVER---RLKYARK 392

Query: 423 WVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESKSTFSVDELNNVLFEVAKKR 482
           W+EKYAPD++KF I PE    E  E  ++ +   A+ +  +S    +E++ ++++V+K+ 
Sbjct: 393 WLEKYAPDNIKFEI-PEKVTAEFSEEEKKFLRAYAERL--RSDMKPEEIHTLVYDVSKEV 449

Query: 483 GISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRRLR 523
           GI S + F  +YK  +GK  GPR+  F+ SL  ++V  R++
Sbjct: 450 GIKSSKAFQAIYKAILGKTYGPRVGYFIKSLGVEWVRERIK 490


>sp|O27585|SYK_METTH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7450806|pir||G69072 conserved hypothetical protein
           MTH1542 - Methanobacterium thermoautotrophicum (strain
           Delta H) >gi|2622662|gb|AAB86016.1| (AE000914) conserved
           protein [Methanobacterium thermoautotrophicum]
           Length = 544
           
 Score =  332 bits (841), Expect = 8e-90
 Identities = 186/537 (34%), Positives = 304/537 (55%), Gaps = 23/537 (4%)

Query: 1   MVIVVHWADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGY 60
           ++ + HW + +AD++ +ER + + +VV SG + SG +H+GN  ++F A  +  +L+  G+
Sbjct: 18  VISLKHWIERIADEL-KER-DVEEHVVASGTSISGSIHIGNSCDVFIASSIAKSLKKDGF 75

Query: 61  EVRHIHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKE 120
           + R + + DD+D  RKVP  +P  +++YLG+P S +P P GC +S+ EHF   F   ++ 
Sbjct: 76  KSRTVWIADDHDPLRKVPYPLPESYEKYLGVPYSMIPCPEGCCESFVEHFQRPFLEALER 135

Query: 121 LGIEVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYC 180
             I VE    + +Y  G Y++ IR + E   +I EI N++R+     PL ++W P    C
Sbjct: 136 FRIGVEHYSGARMYTEGLYNDYIRTSLERAPEIREIFNRFRD----RPLRDDWLPYNPIC 191

Query: 181 PE--HRKEAEIIEWDGEWKVKYRCPEGHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEP 238
            +       E  ++ G+  V+YRC  G +G +DI+SG  KL WRV+W  RW    V  EP
Sbjct: 192 EKCGRVNTTEAYDFSGD-TVRYRCECGFDGEMDIKSGLGKLTWRVEWAARWKILGVTCEP 250

Query: 239 AGKDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNVILLSDLYE 298
            GKDH A+G SYD    I + I+   AP  + YE++ ++GE   MS S+G         E
Sbjct: 251 FGKDHAASGGSYDVSSIISEEIFDYPAPYPVPYEWITLRGE--AMSKSRGVFFTPGQWLE 308

Query: 299 VLEPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEE--LKRT 356
           +  P  + +   R +P K    +  M  L+L D+FD+ ERIY+G+EDA  + EE  L+  
Sbjct: 309 IGPPESLNYFIFRSKPMKHKDFNPDMPFLDLMDQFDRTERIYYGMEDAASEKEEQKLRNI 368

Query: 357 YELSNPRIPNRLIAQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKE--------LERE 408
           Y +S       L  +  +RF+ V  Q+   D + +  +L     +P+E        L  +
Sbjct: 369 YRVSMIE-EFDLPLRPSYRFMTVACQIAGDDPERLYDILRRNSQLPEELMDLELDQLTDK 427

Query: 409 DIERIRLRIRLAKNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESKSTFSV 468
            +E++  RI   KNW+  YAP+ VKF +  E P +E+ E   + +++VA  +ES+   S 
Sbjct: 428 QLEQLNERIENVKNWLRLYAPEFVKFQVQEELPDVELSEPQLKFLQDVADLMESRE-MSA 486

Query: 469 DELNNVLFEVAKKRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRRLRLE 525
           +EL++ ++ + ++ G+  ++ F  +Y++ IGK+ GPR ASFL SL++DFV+RRLRLE
Sbjct: 487 EELHDEMYSILRRHGLKPQKAFQAIYRVLIGKKMGPRAASFLLSLERDFVIRRLRLE 543


>sp|P57677|SYK_THEAC LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|10640474|emb|CAC12288.1| (AL445066) lysyl-tRNA
           synthetase (lysS) related protein [Thermoplasma
           acidophilum]
           Length = 507
           
 Score =  298 bits (756), Expect = 8e-80
 Identities = 177/514 (34%), Positives = 280/514 (54%), Gaps = 21/514 (4%)

Query: 12  ADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRHIHMWDDY 71
           AD ++++     R  V +GI+PSG +HVGN RE+ T  I+  A+  +G E   I++ DD 
Sbjct: 7   ADALVKDLSGPQR--VSTGISPSGPIHVGNMREILTGDILFKAITKRGLESDFIYLCDDM 64

Query: 72  DRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELGIEVEFLYAS 131
           D  RKV   +  +++ Y+G P+  +P P G    Y+++++E F R +KE  I    +  S
Sbjct: 65  DPLRKVYPFLSKDYERYVGQPLKNIPAPQGA-GKYSDYYLEPFVRVMKEANIPARVIKTS 123

Query: 132 ELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYCPEHRK--EAEI 189
           +LY+ G  ++    A   +EKI +IL    E      +  +++P    C +  +     +
Sbjct: 124 DLYESGMLAQACDIAINNREKIKDIL----ETVSGRKIEGDFYPYEPLCEKCGRISTTHV 179

Query: 190 IEWDGEWKVKYRCPEGHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAGKDHLAAGSS 249
           I +   +  +Y C  GH G+ DIR    K+ WRV+WP +W    V  EP GKDH A G S
Sbjct: 180 ISYSYPY-AEYACKCGHHGFADIRKAEGKMPWRVEWPAKWFALKVTVEPFGKDHGAPGGS 238

Query: 250 YDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVLEPGLVRFIY 309
           YDTG+ I + ++G E P+ LMYE + +KG KG M  S G  I  S++ EV+ P L+R++ 
Sbjct: 239 YDTGRRIAREVFGIEPPVPLMYERIILKG-KGAMHSSTGLAIAASEIMEVIPPDLLRYMI 297

Query: 310 ARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEELKRTYELSNPRIPNRLI 369
           AR  P + I  D GMG+L L DE +K++  YF    +  + +     Y L N    +R  
Sbjct: 298 ARVNPGRHIDFDPGMGILALSDELEKLQDAYFENRASLDEDQAAMVEYSLVN---KDRKP 354

Query: 370 AQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDIERIRLRIRLAKNWVEKYAP 429
               FR L  LVQ+   +++ + +V   Q   P +    D    R  I  A+ W+E+YAP
Sbjct: 355 YPVDFRHLVTLVQIYRTEDEILRAVKKGQ---PSDFIEAD---FRKEIEYARRWLERYAP 408

Query: 430 DSVKFSILPEPPKIEIDESVREAMEEVAKWIESKSTFSVDELNNVLFEVAKKRGISSKEW 489
           +SVKF ILP   KIE+ +S    + +    IE    ++ + +++ ++E+++K   + +  
Sbjct: 409 ESVKFRILPVDQKIELSDSDLAILSDFLNGIED-MPWNSESIHDRIYEISQKFKTNPESV 467

Query: 490 FSTLYKLFIGKERGPRLASFLASLDKDFVVRRLR 523
           F+  Y++FIGK+RGPRL  FL +L KDFV  R+R
Sbjct: 468 FTLFYRVFIGKDRGPRLGYFLFNLGKDFVRERIR 501


>gb|AAG20183.1| (AE005095) lysyl-tRNA synthetase; LysS [Halobacterium sp. NRC-1]
           Length = 548
           
 Score =  267 bits (676), Expect = 2e-70
 Identities = 170/550 (30%), Positives = 279/550 (49%), Gaps = 49/550 (8%)

Query: 7   WADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRHIH 66
           WAD  AD+++ +   ++  V++ GI+PSG  H+GN  E+   Y V   LR++G+EVR + 
Sbjct: 18  WADAAADRVL-DGDPEEPIVIKGGISPSGVPHLGNMNEIMRGYFVAAVLRERGHEVRQVF 76

Query: 67  MWDDYDRFRKVPRNVPPEWKEY--------------LGMPVSEVPDPWGCHDSYAEHFME 112
             DD D  R +PR +     E               LG P +E+PDP+GC DSY  HF  
Sbjct: 77  TSDDRDPLRGLPRKLADLDGEVVALGDVNAGALGQNLGAPYTEIPDPFGCCDSYGAHFSN 136

Query: 113 KFEREVKELGIEVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPEN 172
             +     LG++VE +  +E Y  G + E  R   E      ++L +Y++   +  +P N
Sbjct: 137 LIQSSADRLGVDVEMVSNTETYANGGFEEVTRYLLEHVTAARDVLGEYQDKVDEEYVPFN 196

Query: 173 WWPAMVYCPEHRKEAEIIEWDGEWKVKYRCPE-----------GHEGWVDIRSGNVKLRW 221
             P    C +  +    ++ D    V+Y C +           GHEG   +R G  KL W
Sbjct: 197 --PICEACGKVTETVTDVDADA-GTVEYVCTDMDAGDQTIEGCGHEGTATLREG--KLPW 251

Query: 222 RVDWPMRWAHFDVDFEPAGKDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKG 281
           R +WP +W    VD+EP GKDH  A  S+ +G +I + + G E P  ++YE+  + GE  
Sbjct: 252 RFEWPAQWRTLGVDYEPFGKDH--AEGSWPSGTDISRNVLGDEPPTPMVYEWFTLDGE-- 307

Query: 282 KMSGSKGNVILLSDLYEVLEPGLVRFIYARH-RPNKEIRIDLGMGLLNLYDEFDKVERIY 340
             S S G+VIL+ D+  +LE  +VR+ +++  R  ++  I+    L  L DEFD++ER+Y
Sbjct: 308 PFSSSAGHVILVQDVLALLELPVVRYFFSKDPRRARDFSIE---HLDQLVDEFDRMERVY 364

Query: 341 FG--VEDAKGDVEELKRTYELSNPRIPNRLIAQAPFRFLAVLVQMPHLDEDGII--SVLT 396
           FG   + ++ + E   R Y L    I    + + PF F AVL     + ED  +   +  
Sbjct: 365 FGEAADASEDERERAARVYPLLVDDIDADRV-RIPFTFAAVL----GMTEDSALREEIAR 419

Query: 397 NQGHVPKELEREDIERIRLRIRLAKNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEV 456
            +GH+P + + + +     R+  A+ W  +   +        E P  + D++   A++E+
Sbjct: 420 REGHIPADADADTVADALTRVERAREWARRTNNEFNYRLARAEIPAHDFDDATAAALDEL 479

Query: 457 AKWIESKSTFSVDELNNVLFEVAKKRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKD 516
           A +++ +     + L   ++E AK+  I    +F+  Y+LF  +++GP+L  FLA LD++
Sbjct: 480 AAFLDDEDP-DGEALQGEIYEAAKRHDIDIGAFFAAGYRLFFDEDQGPKLGPFLAKLDRE 538

Query: 517 FVVRRLRLEG 526
           FVV RLR EG
Sbjct: 539 FVVTRLRREG 548


>sp|Q9X895|SYK_STRCO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7480963|pir||T36123 probable lysyl-tRNA synthetase -
           Streptomyces coelicolor  (fragment)
           >gi|4678917|emb|CAB41289.1| (AL049707) putative
           lysyl-tRNA synthetase [Streptomyces coelicolor A3(2)]
           Length = 545
           
 Score =  252 bits (638), Expect = 5e-66
 Identities = 170/546 (31%), Positives = 269/546 (49%), Gaps = 60/546 (10%)

Query: 26  VVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRHIHMWDDYDRFRKVPRNVP--- 82
           VV SG++PSG +H+GN RE+ T ++V   +R +G+EVRH+  WDDYDR+RKVP  VP   
Sbjct: 1   VVASGLSPSGPIHLGNLREVMTPHLVADEVRRRGHEVRHLISWDDYDRYRKVPAGVPGVD 60

Query: 83  PEWKEYLGMPVSEVPDPWGC-HDSYAEHFMEKFEREVKELGIEVEFLYASELYKRGEYSE 141
             W E++G P++ VP P G  H ++AEHF       + E+G+E + +  +  Y  G Y E
Sbjct: 61  ESWAEHIGKPLTSVPAPKGSPHPNWAEHFKAAMVDSLAEMGVEFDGISQTAQYTSGVYRE 120

Query: 142 EIRKAFEGKEKIMEILNKYR-----EIAKQPPLPE----------------------NWW 174
           +I  A + +  I  IL++YR         Q PL E                       ++
Sbjct: 121 QILHAMKHRRDIDAILDQYRTKKAPAKKSQKPLDEAELEAAEGSGAAAEDDGSSGSAGYF 180

Query: 175 PAMVYCPEHRKEAEIIEW--DGEWKVKYRCPE-GHEGWVDIRSGN-VKLRWRVDWPMRWA 230
           P   YC    K+   +    D   ++ Y C   G    V +   N  KL W+VDWPMRWA
Sbjct: 181 PYKPYCGNCEKDLTTVTAYDDDSTELTYACTACGFSETVRLSEFNRGKLVWKVDWPMRWA 240

Query: 231 HFDVDFEPAGKDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKGNV 290
           +  V FEP+G DH + GSS+  G +I+  I+G E P+  MY FVGI G   KMS SKG V
Sbjct: 241 YEGVVFEPSGVDHSSPGSSFQVGGQIV-GIFGGEQPIGPMYAFVGISG-MAKMSSSKGGV 298

Query: 291 ILLSDLYEVLEPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDV 350
              +D  +++EP L+R++YAR RPN+  +I     +  LYDE+D+++           D 
Sbjct: 299 PTPADALKIMEPQLLRWLYARRRPNQSFKIAFDQEIQRLYDEWDRLDAKVADGSALPADA 358

Query: 351 EELKRTYELSNPRIPNRLIAQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDI 410
               R    +   +P R     P+R LA +  +    ED  + +L   G +        +
Sbjct: 359 AAHARAVGTAAGELP-RTPRPLPYRTLASVADITAGHEDQALRIL---GELDPANPIASL 414

Query: 411 ERIRLRIRLAKNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIES--KSTFSV 468
           +  R R   A+ W+  + P   + +I+ + P  E+ +S+ E   +  + +       +S+
Sbjct: 415 DEARPRYDKAEAWINTHVPADQR-TIVRQEPDAELLKSLDEPSRQSLRLLLDGLADHWSL 473

Query: 469 DELNNVLFEVAKKRG----------------ISSKEWFSTLYKLFIGKERGPRLASFLAS 512
           D L + ++ V K +                  + + +F+ LY L +G++ GPRL + L +
Sbjct: 474 DGLTHHVYGVPKVQAGFPADATPKELPPEIKTAQRTFFALLYHLLVGRDTGPRLPTLLLA 533

Query: 513 LDKDFV 518
           + +D V
Sbjct: 534 VGQDRV 539


>sp|Q9YFT9|SYK_AERPE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7450809|pir||F72771 probable lysyl-tRNA Synthetase
           APE0161 - Aeropyrum pernix  (strain K1)
           >gi|5103551|dbj|BAA79072.1| (AP000058) 562aa long
           hypothetical lysyl-tRNA Synthetase [Aeropyrum pernix]
           Length = 562
           
 Score =  229 bits (577), Expect = 8e-59
 Identities = 172/552 (31%), Positives = 271/552 (48%), Gaps = 54/552 (9%)

Query: 5   VHWADYVADKI---IRERGEKDRYVVESGITPSGYVHVGNFR-ELFTAYIVGHALRDKGY 60
           VHW D +  ++   ++ RG KD Y+   G++ SG  H+G  R E+     V   L  +G+
Sbjct: 20  VHWVDKLVAELEAKLQNRG-KDEYIFNGGLSVSGLQHIGRLRGEVLLGEAVRRELEKRGF 78

Query: 61  EVRH------IHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKF 114
            V+       +  W   D  R+   + P   + Y+G P+  VPDP GCH S+ +HF   F
Sbjct: 79  RVKQLLTLYTVDPWKGKDEQRREFPD-PKAAERYVGWPLDRVPDPKGCHASWVDHFWSDF 137

Query: 115 EREVKELGI----EVEFLYASELYKRGEYSEEIRK-AFEGKEKIMEILNKYREIAKQPPL 169
              +   G+    ++E +   ELYK G   E I       +++I  ++NKYR    + P 
Sbjct: 138 GPYI---GVFTDGKIEVVTTRELYK-GRLKEFITTMVLPRRDEIRRVINKYRG---RKPY 190

Query: 170 PENWWPAMVYCPEHRK--EAEIIEWDGEWKVKYRCPE-GHEGWVDIRSGNVKLRWRVDWP 226
            E W P    C    +    E +E  G  +V+YRC   G++G   I     KL WR++W 
Sbjct: 191 QEGWIPLEPRCARCGRIDSTEALEILGGERVRYRCSYCGYQGESSIEDS--KLNWRIEWA 248

Query: 227 MRWAHFDVDFEPAGKDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIK--GEKGKMS 284
             W    VDFEP GKDH   G S D+  E+ + + G E P  + YE+V ++  G +  MS
Sbjct: 249 GVWWSLGVDFEPYGKDHATPGGSRDSAAELAR-LLGFEPPEGVWYEWVSLRAGGREADMS 307

Query: 285 GSKGNVILLSDLYEVLEPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVE 344
            S    I   +  ++  P ++RFIY  H P + + +DL   + + Y ++ + ERIYFG+E
Sbjct: 308 SSGFTGITPREWLDIAHPQILRFIYFLHPPTRRVVVDLS-EIPSYYSQYYRAERIYFGIE 366

Query: 345 DAKGDVEE---LKRTYELSNP-RIPNRLIAQAPFRFLAVLVQM---PHLDEDGI--ISVL 395
           +A   VEE   L RTYELS+P   P +  +Q P+   A++ Q+     L  DG+  +   
Sbjct: 367 EA-STVEETRYLARTYELSHPSNPPAKPPSQIPYSHAAIVAQVVGPERLWTDGLERLKRA 425

Query: 396 TNQGHVPKELEREDIERIRLRIRLAKNWVEKYAPDSVKFSILPEPPKIEIDESVR-EAME 454
              GH     +   I   +  +  A  W  +YAP  +KF I   PP+  +    + + +E
Sbjct: 426 GLLGH-----DEYSIRWAKELLEKAYKWARRYAPKHLKFEIPDSPPEDALRRIEKPDLLE 480

Query: 455 EVAKWIESKSTFSVDELNNVLFEVAKKRGISSKE---WFSTLYKLFIGKERGPRLASFLA 511
           ++A+ +ES   +S + +   L E  +  G+SS E   ++   Y   +G+  GPR A  L+
Sbjct: 481 KLAEVLESVEEWSEERIKQALVEFGE--GMSSSERRRFYRDFYLAIVGRPEGPRAAPLLS 538

Query: 512 SLDKDFVVRRLR 523
            +D+ FVV RLR
Sbjct: 539 LMDRGFVVDRLR 550


>sp|O74059|SYK_CERSY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|11280298|pir||T31311 lysine--tRNA ligase (EC
           6.1.1.6) - Cenarchaeum symbiosum
           >gi|3599397|gb|AAC62702.1| (AF083072) lysyl tRNA
           synthetase [Cenarchaeum symbiosum]
           Length = 524
           
 Score =  186 bits (467), Expect = 6e-46
 Identities = 155/540 (28%), Positives = 241/540 (43%), Gaps = 50/540 (9%)

Query: 7   WADYVADKII-RERG---EKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRDKGYEV 62
           W D +A +++ RE     + +   VESG+  SG  H+G+  +   AY VG A+ D G+  
Sbjct: 9   WIDKLAHELVEREEALGRDTEMINVESGLGASGIPHMGSLGDAVRAYGVGLAVGDMGHSF 68

Query: 63  RHIHMWDDYDRFRKVPRNVPPEWKEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELG 122
           R I  +DD D  RKVP  +P   +E++  PVS +PDP+GCHDSY  H        +  LG
Sbjct: 69  RLIAYFDDLDGLRKVPEGMPSSLEEHIARPVSAIPDPYGCHDSYGMHMSGLLLEGLDALG 128

Query: 123 IEVEFLYASELYKRGEYSEEIRKAFEGKEKIMEILNKYREIAKQPPLPENWWPAMVYCPE 182
           IE +F  A + Y+ G  +E+I +       I E   K  E+  Q     +  P    C +
Sbjct: 129 IEYDFRRARDTYRDGLLAEQIHRILSNSSVIGE---KIAEMVGQEKFRSS-LPYFAVCEQ 184

Query: 183 HRK--EAEIIEWDGE-WKVKYRCPE-----------GHEGWVDIRSGNVKLRWRVDWPMR 228
             K   AE +E+  +  KV+YRC +           GHEG  D      KL W+V++  R
Sbjct: 185 CGKMYTAESVEYLADSRKVRYRCGDAEVGGRKIAGCGHEGEADTGGAGGKLAWKVEFAAR 244

Query: 229 WAHFDVDFEPAGKDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYEFVGIKGEKGKMSGSKG 288
           W  FDV FE  GKD +    S      +   I     P    YE    KG K K+S S G
Sbjct: 245 WQAFDVRFEAYGKDIM---DSVRINDWVSDEILSSPHPHHTRYEMFLDKGGK-KISKSSG 300

Query: 289 NVILLSDLYEVLEP-GLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAK 347
           NV+          P  ++  +Y R    +E+ ++    + +L DE+  ++R YF      
Sbjct: 301 NVVTPQKWLRYGTPQSILLLMYKRITGARELGLE---DVPSLMDEYGDLQREYFAGGGRG 357

Query: 348 GDVEELKRTYELSNPRIPNRLIAQAPFRFLAVLVQMPHLDEDG----IISVLTNQGHVPK 403
           G   E K         +        P     +LV++  L  +     +   L   G +  
Sbjct: 358 GKAREAKNRGLFEYTNLLEAQEGPRPHAGYRLLVELSRLFRENRTERVTKKLVEYGVI-- 415

Query: 404 ELEREDIERIRLRIRLAKNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESK 463
           +     IER+   I LA N    YA D        E  ++E+D + R A+ E+A+ + S 
Sbjct: 416 DGPSPGIERL---IALAGN----YADDMYS----AERTEVELDGATRGALSELAEMLGSA 464

Query: 464 STFSVDELNNVLFEVAKKRGISSKEWFSTLYKLFIGKERGPRLASFLASLDKDFVVRRLR 523
                  L +V++ VAK  G+  +++F  LY++ +    GPR+  F+  + ++ V   +R
Sbjct: 465 PE---GGLQDVIYGVAKSHGVPPRDFFKALYRIILDASSGPRIGPFIEDIGREKVAGMIR 521


>sp|Q9ZDF8|SYK_RICPR LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7467883|pir||D71694 lysine--tRNA ligase (EC 6.1.1.6)
           (lysS) RP371 - Rickettsia prowazekii
           >gi|3860930|emb|CAA14830.1| (AJ235271) LYSYL-tRNA
           SYNTHETASE (lysS) [Rickettsia prowazekii]
           Length = 528
           
 Score =  150 bits (376), Expect = 3e-35
 Identities = 134/513 (26%), Positives = 228/513 (44%), Gaps = 35/513 (6%)

Query: 8   ADYVADKIIRERGEKDRYVVESGITPSGYVHVGNFRELFTAYIVGHALRD-KGYEVRHIH 66
           A  + D +  +  EK   + E+G  PSG  H+G F E     +V  A         + I 
Sbjct: 19  AKKILDSLNGKAPEKGYILFETGYGPSGLPHIGTFAENARMVMVQKAFEQLSDIPTKLIC 78

Query: 67  MWDDYDRFRKVPRNVP-PEW-KEYLGMPVSEVPDPWGCHDSYAEHFMEKFEREVKELGIE 124
             DD D  RKVP N+P PE   +Y+ MP++ +PDP+G   SY  +   K    + + G +
Sbjct: 79  FSDDMDGLRKVPSNIPHPEMVAQYMDMPLTSIPDPFGKCKSYGHYMNAKLCAFLDKFGFK 138

Query: 125 VEFLYASELYKRGEYSEEIRKAFEGKEKIMEI-LNKYREIAKQPPLPENWWPAMVYCPEH 183
            EF  ++  YK G + E + +  E  ++IM + L  +R+  K       + P M  CP+ 
Sbjct: 139 YEFYSSTNCYKAGMFDEMLIRVLEKYDEIMALMLPTFRDERKT-----TYAPFMPICPKT 193

Query: 184 RK--EAEIIEWDGE-WKVKYRCPEGHEGWVDIRSGNVKLRWRVDWPMRWAHFDVDFEPAG 240
            K  +  I +WD +   V Y+  +G++  V +  G+ KL+W+ D+ MRWA   VD+E  G
Sbjct: 194 GKVLQVPIEKWDAKAGTVSYKDEDGNDVEVPVTGGHCKLQWKPDFGMRWAALKVDYEMYG 253

Query: 241 KDHLAAGSSYDTGKEIIKAIYGKEAPMSLMYE-FVGIKGEKGKMSGSKGNVILLSD-LYE 298
           KDHLA    Y    EI + + GK  P+   YE F+   GE  K+S S+GN I + D L  
Sbjct: 254 KDHLANSRLY---SEICRILGGK-PPVQFCYELFLDANGE--KISKSRGNSISVDDWLKY 307

Query: 299 VLEPGLVRFIYARHRPNKEIRIDLGMGLLNLYDEFDKVERIYFGVEDAKGDVEELKRTYE 358
                +  F+Y      K +  DL   +    DE+  + + Y   ED           Y 
Sbjct: 308 ASVESIALFMYKNPARAKRLFFDL---IPKNVDEYITLNQKYHLEEDMV--TRFANPVYH 362

Query: 359 LSNPRIPNRLIAQAPFRFLAVLVQMPHLDEDGIISVLTNQGHVPKELEREDIERIRLRIR 418
           + +  +P        +  L  L  + +  +  ++     + + PK           L   
Sbjct: 363 IHHGNVPKIETFGLTYSLLLNLTAVCNTSDKSVLWGFITK-YEPKATPNTSTYLDHL-TE 420

Query: 419 LAKNWVEKYAPDSVKFSILPEPPKIEIDESVREAMEEVAKWIESKSTFSVDELNNVLFEV 478
            A  +   +      + ++ E  KI I   + + +  ++   E +S      +   ++++
Sbjct: 421 FAIRYYNDFIQTHKSYLVVSEKHKI-ILHDILDMLSNISDQTEEES------IQKAIYDI 473

Query: 479 AKKRGISS-KEWFSTLYKLFIGKERGPRLASFL 510
             K G  + + +F  LY++ +G+  GPRL +F+
Sbjct: 474 GMKSGYENLRYYFKDLYQILLGQNEGPRLGTFI 506


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.140    0.431 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 212412843
Number of Sequences: 2977
Number of extensions: 9889628
Number of successful extensions: 24858
Number of sequences better than 1.0e-10: 15
Number of HSP's better than  0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 24762
Number of HSP's gapped (non-prelim): 15
length of query: 526
length of database: 189,106,746
effective HSP length: 53
effective length of query: 473
effective length of database: 157,386,935
effective search space: 74444020255
effective search space used: 74444020255
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 167 (69.5 bits)