BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0146 (PAB0146) DE:MULTIDRUG RESISTANCE PROTEIN
(387 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75211 multidrug resistance protein PAB0146 - Pyrococcus ab... 767 0.0
pir||B71247 hypothetical protein PH0233 - Pyrococcus horikoshii ... 623 e-177
gi|11498923 multidrug resistance protein [Archaeoglobus fulgidus... 105 8e-22
pir||S74875 quinolone resistance protein norA - Synechocystis sp... 104 2e-21
dbj|BAB03956.1| (AP001507) multidrug-efflux transporter [Bacillu... 102 7e-21
pir||G64494 quinolone resistance protein norA homolog - Methanoc... 98 2e-19
pir||B70065 antibiotic resistance protein homolog ywoG - Bacillu... 85 2e-15
sp|P39637|YWFA_BACSU HYPOTHETICAL 44.5 KD PROTEIN IN ROCC-PTA IN... 83 5e-15
pir||D71112 hypothetical protein PH0667 - Pyrococcus horikoshii ... 83 5e-15
emb|CAA07482.1| (AJ007367) multi-drug resistance efflux pump [St... 81 2e-14
pir||H65004 hypothetical protein b2322 - Escherichia coli (strai... 80 4e-14
dbj|BAA75389.1| (AB013375) YhcA [Bacillus halodurans] 79 8e-14
dbj|BAB04273.1| (AP001508) multidrug resistance protein (efflux ... 79 8e-14
pir||E75048 multidrug resistance protein PAB0913 - Pyrococcus ab... 78 1e-13
gb|AAF18272.1| (AF088897) transcriptional regulatory protein [Zy... 77 3e-13
gb|AAD10060.1| (AF113952) multidrug-efflux transporter [Campylob... 75 1e-12
pir||D81282 probable efflux protein Cj1375 [imported] - Campylob... 75 1e-12
dbj|BAB06311.1| (AP001516) unknown conserved protein [Bacillus h... 75 1e-12
pir||E75290 probable multidrug-efflux transporter - Deinococcus ... 73 6e-12
sp|P25744|YCEE_ECOLI HYPOTHETICAL 43.9 KDA PROTEIN IN MSYB-HTRB ... 72 1e-11
pir||T45544 hypothetical protein 3 [imported] - Klebsiella pneum... 70 4e-11
pir||C82644 transcription regulator XF1749 [imported] - Xylella ... 70 4e-11
dbj|BAB05798.1| (AP001514) unknown conserved protein in others [... 70 5e-11
>pir||B75211 multidrug resistance protein PAB0146 - Pyrococcus abyssi (strain
Orsay) >gi|5457646|emb|CAB49137.1| (AJ248283) MULTIDRUG
RESISTANCE PROTEIN [Pyrococcus abyssi]
Length = 387
Score = 767 bits (1960), Expect = 0.0
Identities = 387/387 (100%), Positives = 387/387 (100%)
Query: 1 MLKNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGY 60
MLKNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGY
Sbjct: 1 MLKNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGY 60
Query: 61 IGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAV 120
IGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAV
Sbjct: 61 IGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAV 120
Query: 121 DLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLV 180
DLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLV
Sbjct: 121 DLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLV 180
Query: 181 WREVGEIKVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFLPALYKVSGLGQSV 240
WREVGEIKVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFLPALYKVSGLGQSV
Sbjct: 181 WREVGEIKVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFLPALYKVSGLGQSV 240
Query: 241 FGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAA 300
FGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAA
Sbjct: 241 FGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAA 300
Query: 301 ISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRGYEGV 360
ISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRGYEGV
Sbjct: 301 ISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRGYEGV 360
Query: 361 FPVISILPLISIAMAHIPLLWGRNDEG 387
FPVISILPLISIAMAHIPLLWGRNDEG
Sbjct: 361 FPVISILPLISIAMAHIPLLWGRNDEG 387
>pir||B71247 hypothetical protein PH0233 - Pyrococcus horikoshii
>gi|3256622|dbj|BAA29305.1| (AP000001) 387aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 387
Score = 623 bits (1589), Expect = e-177
Identities = 297/386 (76%), Positives = 345/386 (88%)
Query: 1 MLKNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGY 60
ML++LWFLNFST FFFLGIS+LNPLISPYAITLGA+PFLVG+VAGV SG+SL SKL GGY
Sbjct: 1 MLRDLWFLNFSTLFFFLGISVLNPLISPYAITLGAEPFLVGLVAGVTSGVSLVSKLFGGY 60
Query: 61 IGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAV 120
IGD+GYRFHAMFLGN+LGI SG+ YI SA+ SI +FA+GRA+HG MGIFFPSSLSSAV
Sbjct: 61 IGDRGYRFHAMFLGNILGIISGVFYIISAMFHSIFIFAIGRAIHGVGMGIFFPSSLSSAV 120
Query: 121 DLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLV 180
DLAPKGRVGEALGWRGMMFSLGNI+GP IGGF+SD+FGF AF +I+FS++GAIFVL V
Sbjct: 121 DLAPKGRVGEALGWRGMMFSLGNIIGPGIGGFVSDRFGFVSAFLLAILFSIIGAIFVLAV 180
Query: 181 WREVGEIKVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFLPALYKVSGLGQSV 240
WREVGEIK +K EE SGYREL++ FFI+ACLSLFFIS+AYSGVVTFLPALYKVSGLGQ +
Sbjct: 181 WREVGEIKFEKREERSGYRELIRVFFITACLSLFFISVAYSGVVTFLPALYKVSGLGQGI 240
Query: 241 FGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAA 300
FGLYMMIMG++SF RVVGGRSAD+ GPIPV R+GV I ++Y LL+KFKFPP+SY+ A
Sbjct: 241 FGLYMMIMGVSSFLTRVVGGRSADRFGPIPVARIGVGMILISYALLVKFKFPPHSYLVAF 300
Query: 301 ISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRGYEGV 360
ISGAGFGL+ PALQYMALAKLPG+IRTMGSSIYTMFFDLGMLSGQVGLG VAQ+ GYEGV
Sbjct: 301 ISGAGFGLTYPALQYMALAKLPGRIRTMGSSIYTMFFDLGMLSGQVGLGYVAQLSGYEGV 360
Query: 361 FPVISILPLISIAMAHIPLLWGRNDE 386
FPV+++LPL+S+ + +IP++W +E
Sbjct: 361 FPVVALLPLLSLLIVNIPVIWRDKNE 386
>gi|11498923 multidrug resistance protein [Archaeoglobus fulgidus]
>gi|7483887|pir||D69415 multidrug resistance protein
homolog - Archaeoglobus fulgidus
>gi|2649251|gb|AAB89920.1| (AE001012) multidrug
resistance protein [Archaeoglobus fulgidus]
Length = 371
Score = 105 bits (260), Expect = 8e-22
Identities = 92/365 (25%), Positives = 163/365 (44%), Gaps = 17/365 (4%)
Query: 8 LNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIGDKGYR 67
L S FF + +S + P+I YA +LGA FL AGV + + G + + R
Sbjct: 4 LILSGFFAYASLSCVIPIIPSYASSLGASVFLSAFAAGVFALFPAIAMTPFGMLSEVYGR 63
Query: 68 FHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDLAPKGR 127
+ G V + + LLY+ S+ + ++VF+ R +HG ++ PS + D++ + R
Sbjct: 64 RRFLVAGAVTSLLASLLYLQSS-TAELLVFS--RTLHGLGSALYIPSINALVADISEESR 120
Query: 128 VGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWREVGEI 187
GEA+G LG GP GGF+SD FG F ++VFS + V VG
Sbjct: 121 RGEAMGKLQTALMLGFFAGPLAGGFVSDFFGVKAVFLLALVFSAAALVPV------VGVR 174
Query: 188 KVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTF--LPALYKVSGLGQSVFGLYM 245
+ K E ++ + P ++ ++ F+ MA + +P + Q GL +
Sbjct: 175 ERSKGGEIG--KQFIFPRKLAPLFAVMFVGMATGSSLALFAIPFYAPELNISQQQAGLLV 232
Query: 246 MIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAAISGAG 305
++ L S +RV G AD+ G +G+ L K F P ++++ + GAG
Sbjct: 233 AVLFLFSAIIRVPAGILADRAGRNVTALLGMVVTGLGLFSAFKPDF-PFLFLASLLCGAG 291
Query: 306 FGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRGYEGVFPVIS 365
G+ A+ + A + + MG + + G+ +G G +A ++ + +++
Sbjct: 292 NGIVNTAV-FAAASDYENRGYAMG--VANTVLNAGIFAGTTLAGFMAGFLSFQSMMLILA 348
Query: 366 ILPLI 370
L+
Sbjct: 349 AATLL 353
>pir||S74875 quinolone resistance protein norA - Synechocystis sp. (strain PCC
6803) >gi|1652918|dbj|BAA17836.1| (D90909) quinolene
resistance protein NorA [Synechocystis sp.]
Length = 418
Score = 104 bits (257), Expect = 2e-21
Identities = 100/384 (26%), Positives = 172/384 (44%), Gaps = 25/384 (6%)
Query: 3 KNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIG 62
K L S F+L ++ L P + YA +GA VG + G + L S++ G +
Sbjct: 16 KTFALLFASVLMFWLSLTALLPTLPMYAQDVGATKQQVGWIMGSFALGLLGSRIWIGQLV 75
Query: 63 DKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDL 122
D+ R A+ +G ++ + L Y+ +A G++M RA HG + + S VDL
Sbjct: 76 DRRGRKIAIVIGALVVALAPLGYLLTATVGALMAI---RAFHGICLAAYTTGYNSLVVDL 132
Query: 123 APKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWR 182
+P + GE +G+ + +G GPA+G +IS G+ F +S S+LG I ++L +
Sbjct: 133 SPPQQRGEIIGYMSLAVPIGMGFGPAVGAYISQSIGYEFLFIAS---SLLGFISLVLALQ 189
Query: 183 EVGEIKVDKHEEHSGYRELLKPFFISACLS----------LFFISMAYSGVVTFLPALYK 232
D+ + + +P I L+ L I + + + TFLP +
Sbjct: 190 VRENRPPDQSSAEDVFGDRPRPRSIGKLLTSRSMAVPTLVLLLIGLLFGNLATFLPLFVR 249
Query: 233 VSGLGQSVFGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLL-LLKFKF 291
L + G++ + +ASF R+ G AD G + + G + YLL ++
Sbjct: 250 EIDLA-TYAGVFYSVAAIASFVPRLFLGSLADTYGR----GLFIVGSLICYLLSMVCLAQ 304
Query: 292 PPNSY---ISAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGL 348
NS+ +AA+ GAG G+ LP + + + R S+ FD G+ +
Sbjct: 305 ADNSWELLTAAALEGAGSGILLPTTIALISDRSSLEERGRVFSVCMSGFDGGIAIAAPIM 364
Query: 349 GLVAQVRGYEGVFPVISILPLISI 372
G++ ++ GY VF + L L +I
Sbjct: 365 GVLNEIFGYRHVFWLSGGLALAAI 388
>dbj|BAB03956.1| (AP001507) multidrug-efflux transporter [Bacillus halodurans]
Length = 387
Score = 102 bits (252), Expect = 7e-21
Identities = 89/348 (25%), Positives = 163/348 (46%), Gaps = 15/348 (4%)
Query: 16 FLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIGDKGYRFHAMFLGN 75
F+ I P+I+PYA++LGA LVG + + S ++ +IGG+ D+ R +++G
Sbjct: 13 FIDTFIQLPIITPYALSLGASETLVGGIVAIYSLANMVGNIIGGHWVDRFGRKRMLYMG- 71
Query: 76 VLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDLAPKGRVGEALGWR 135
+L + LL A +G + FA R +HG A G+ P++ + D A + + + +
Sbjct: 72 MLAVGGVLLLYPLAQTGGQLFFA--RLLHGLAGGVLIPAAFALIGDQAKARQSRKPMAFA 129
Query: 136 GMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWREVGE-IKVDKHEE 194
G + I GPAIGG ++ + F I+ ++L + V L + V E +K +
Sbjct: 130 GASIGIAAITGPAIGGILAAQSRTEYVF---ILVAILFFLSVGLTIKFVPESMKATSRQR 186
Query: 195 ----HSGYRELLKPF-FISACLSLFFISMAYSGVVTFLPALYKVSGLGQSVFGLYMMIMG 249
H G LLK + ACL+ F + ++ + LP L GL + G+ + I G
Sbjct: 187 VSWGHVG--PLLKNVSLMQACLAAFALMVSNGTLAFALPLLVTQLGLTSAATGMLLSIYG 244
Query: 250 LASFFMRVVG-GRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAAISGAGFGL 308
+ + F+ + + ++L P ++ +G+ I ++ +LL + + G GF
Sbjct: 245 ITALFIFITPLNKVYERLYPGRLVVLGLGLIGVSLMLLSFIHTLSLAVVLMVTYGIGFAF 304
Query: 309 SLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRG 356
P++ M + R I+ F LG+++G G+V ++ G
Sbjct: 305 VFPSMNQMVSTASQDEDRGKAYGIFYAVFSLGVVAGSFISGVVTELLG 352
>pir||G64494 quinolone resistance protein norA homolog - Methanococcus
jannaschii >gi|1592184|gb|AAB99579.1| (U67596)
multidrug-efflux transporter (bmr1) [Methanococcus
jannaschii]
Length = 386
Score = 97.9 bits (240), Expect = 2e-19
Identities = 87/378 (23%), Positives = 166/378 (43%), Gaps = 18/378 (4%)
Query: 3 KNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIG 62
KN++ + +TF LG+ + P+++ YA TLGA +G++ G + +++ G +
Sbjct: 6 KNVFVIWITTFTTMLGVGFIAPIMAIYAQTLGATNLEIGLIFGSFALARTVAQIPVGVLS 65
Query: 63 DKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDL 122
D + + G S L+Y +++ F + R G P + S +
Sbjct: 66 DIYGKKFFIVCGTFFYGVSTLMY---NFVSTVLGFLIVRIFTGIFSAFVTPVAGSYIAAI 122
Query: 123 APKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWR 182
APK R+GE +G +LG +GP IGG ++D +G M F+ LG + ++ +
Sbjct: 123 APKTRLGEYMGIFNSAITLGFGIGPFIGGILADMYGIKMPFY---FCGFLGILAAIISYM 179
Query: 183 EVGEIKVDKHEEHSGYRELLKPFFISACLSLFFIS---------MAYSGVVTFLPALYKV 233
++ +I +K++E +++ F + F S M +G+ +L ALY +
Sbjct: 180 KLEDIVFNKNKEKIDVKKISTLFSFEFLKNRNFSSSFIINVSNVMINAGIYAYL-ALYAI 238
Query: 234 S-GLGQSVFGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFP 292
+ + S G + + + ++ G+ DKLG I +I +G+ I LL
Sbjct: 239 NYNITISQVGFMIALTNILMALLQRSFGKLYDKLGNIMII-IGIFIISFGMYLLSTSTTF 297
Query: 293 PNSYISAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVA 352
S I G +S A +A+ +P + ++T ++GM G V G +A
Sbjct: 298 LTILASLTIIAVGSSISSTATTSLAVKDIPTHRKGEAMGLFTTSINIGMFIGAVSFGFLA 357
Query: 353 QVRGYEGVFPVISILPLI 370
+ G ++ +I ++
Sbjct: 358 DILGIANMYKFSAIFSIV 375
>pir||B70065 antibiotic resistance protein homolog ywoG - Bacillus subtilis
>gi|1684651|emb|CAB05383.1| (Z82987) unknown similar to
quinolon resistance protein NorA [Bacillus subtilis]
>gi|2636170|emb|CAB15662.1| (Z99122) similar to
antibiotic resistance protein [Bacillus subtilis]
Length = 396
Score = 84.7 bits (206), Expect = 2e-15
Identities = 70/278 (25%), Positives = 120/278 (42%), Gaps = 16/278 (5%)
Query: 106 FAMGIFFP--SSLSSAV--DLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGM 161
F GI+F ++++ A+ D+ P R GE LG+ M +L +GP +G + F +
Sbjct: 107 FFQGIWFSILTTVTGAIAADIIPAKRRGEGLGYFAMSMNLAMAIGPFLGLNLMRVVSFPV 166
Query: 162 AFFSSIVFSVLGAIFVLLVWREVGEIKVDKHEEHSGYRELLKPFFISACLSL----FFIS 217
F + +F V G + L+ ++ K + +R F L + FIS
Sbjct: 167 FFTAFALFMVAGLLVSFLI-----KVPQSKDSGTTVFRFAFSDMFEKGALKIATVGLFIS 221
Query: 218 MAYSGVVTFLPALYKVSGLGQSVFGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVS 277
YS V ++L K L + G + + + R G+ DK+GP VI +
Sbjct: 222 FCYSTVTSYLSVFAKSVDLSD-ISGYFFVCFAVTMMIARPFTGKLFDKVGPGIVIYPSIL 280
Query: 278 GIFLAYLLLLKFKFPPNSYI-SAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMF 336
IF L +L F + S A+ G G+G +P +Q +A+ K P ++ + F
Sbjct: 281 -IFSVGLCMLSFTHSGLMLLLSGAVIGLGYGSIVPCMQTLAIQKSPAHRSGFATATFFTF 339
Query: 337 FDLGMLSGQVGLGLVAQVRGYEGVFPVISILPLISIAM 374
FD G+ G GL G+ ++ + LI++ +
Sbjct: 340 FDSGIAVGSYVFGLFVASAGFSAIYLTAGLFVLIALLL 377
>sp|P39637|YWFA_BACSU HYPOTHETICAL 44.5 KD PROTEIN IN ROCC-PTA INTERGENIC REGION
>gi|629086|pir||S39734 chloramphenicol resistance
homolog ywfA - Bacillus subtilis
>gi|414003|emb|CAA51635.1| (X73124) ipa-79d [Bacillus
subtilis] >gi|2636311|emb|CAB15802.1| (Z99123) alternate
gene name: ipa-79d~similar to chloramphenicol resistance
[Bacillus subtilis]
Length = 412
Score = 83.1 bits (202), Expect = 5e-15
Identities = 98/390 (25%), Positives = 174/390 (44%), Gaps = 51/390 (13%)
Query: 24 PLISPYAITLGA----------KPFLVGVVAGVASGISLFSKLIGGY------------- 60
PL+ A+T+G P L + +S +S+ + I Y
Sbjct: 16 PLLLALALTMGVFAAGSEELVISPLLPDLAKAFSSDVSVLALSISIYGVMIFIGAPLLVP 75
Query: 61 IGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAV 120
+GDK R ++ G ++ I ++ AL+ +I F LGRA+ G A G F P++ +
Sbjct: 76 LGDKYSRELSLLAGLMIFIIGTVI---CALAQNIFFFFLGRALSGLAAGAFVPTAYAVVG 132
Query: 121 DLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLV 180
D P G+ +G +SL I G +G FI + F+ +F+++G + VLL+
Sbjct: 133 DRVPYTYRGKVMGLIVSSWSLALIFGVPLGSFIGGVLHWRWTFW---IFALMGVLVVLLI 189
Query: 181 WREVGEIKVDKH------EEHSG-YRELLKPFFISACLSLFFISM-AYSGVVTFLPA-LY 231
E+ K+ EE +G +R+ LK + +++ F +M + G+ +FL L
Sbjct: 190 LLEMRRHAQHKNSGKEEIEEPAGTFRDALKVPRVPVYITITFCNMIGFYGMYSFLGTYLQ 249
Query: 232 KVSGLGQSVFGLYMMIMGLASFFMRVVGGRSADKLGPIP--VIRVGVSGIFLAYLLLLKF 289
V G + GL++MI G+ F M V+ G+ AD++G + +I +GV + LA L
Sbjct: 250 DVFTGGNTAAGLFIMIYGI-GFSMSVITGKIADRIGKMRSLLIALGVISVLLACL----- 303
Query: 290 KFPPNSYI----SAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQ 345
+ P S S I G L++ L + L+ + R Y++ +L + G
Sbjct: 304 PYAPASMFLLIASLFIWGLMQSLTVTLLSTI-LSDCSERHRGKVMVFYSLASNLAVTLGS 362
Query: 346 VGLGLVAQVRGYEGVFPVISILPLISIAMA 375
+G V GY V + + + ++ ++
Sbjct: 363 ALMGPVYVAYGYAAVGLICAAITVLGFVLS 392
>pir||D71112 hypothetical protein PH0667 - Pyrococcus horikoshii
>gi|3257075|dbj|BAA29758.1| (AP000003) 413aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 413
Score = 83.1 bits (202), Expect = 5e-15
Identities = 90/385 (23%), Positives = 161/385 (41%), Gaps = 26/385 (6%)
Query: 3 KNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIG 62
+N+ F FF L I P ++ Y +G FLVG+++ + + S + GY+
Sbjct: 29 RNITFFAIGMFFANLAWGIGYPYLTVYMKIIGGTMFLVGLLSVIYNLTSAIFQYPFGYLS 88
Query: 63 DK-GYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVD 121
DK G R + LG +FSG Y+ + ++ R G F P+ + +
Sbjct: 89 DKIGKRKPFIILGV---LFSGTTYVLVIFISTPILLLSLRGTQGALGASFAPAHSALISE 145
Query: 122 LAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLV- 180
L+ RVG G+ + ++G +VG +GG+I K G AF ++ + S++ +F+ V
Sbjct: 146 LST--RVGSMFGFFNFVENMGFMVGNFLGGYIVKKVGIKSAFLATSIVSLVSILFLTQVK 203
Query: 181 -----WREVGEI-------KVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFLP 228
+ +G + +K E S ++L + A ++M SG V
Sbjct: 204 ERERKKKNIGSFLPIREGRESEKVEMKSSAFKMLMKGELGAFYLSVLLAMIASGEVYATV 263
Query: 229 ALYKVSGLGQSVFGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLK 288
+Y G+ G + I LA+ ++ GR DK G ++ + G L + +
Sbjct: 264 PVYFQEKFGEEFVGFLLGIDSLAAALGSLLIGRLIDKYGEKVFYKLAILGYILTF---IG 320
Query: 289 FKFPPNSYISAAI---SGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQ 345
+ + I A + SG + + + ++P + R G + LG + G
Sbjct: 321 YAWATTIIIMALVSLLSGVKWAMITSSASTYVARRVPHRERGQGMGLLNTMMTLGWVIGP 380
Query: 346 VGLGLVAQVRGYEGVFPVISILPLI 370
+ GL+A G+ V + LPLI
Sbjct: 381 LIGGLIADNFGF-SVMLYSTTLPLI 404
>emb|CAA07482.1| (AJ007367) multi-drug resistance efflux pump [Streptococcus
pneumoniae]
Length = 399
Score = 81.1 bits (197), Expect = 2e-14
Identities = 102/380 (26%), Positives = 152/380 (39%), Gaps = 27/380 (7%)
Query: 2 LKNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKL----I 57
L+ WF NF T IS++ P + + LG V AG+A +S S I
Sbjct: 10 LRIAWFGNFLTG---ASISLVVPFMPIFVENLGVGSQQVAFYAGLAISVSAISAALFSPI 66
Query: 58 GGYIGDKGYRFHAMF-LGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSL 116
G + DK R M G + I G L + I + R ++G G F P++
Sbjct: 67 WGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYWLIFL----RLLNGVFAG-FVPNAT 121
Query: 117 SSAVDLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIF 176
+ PK + G ALG G + GP IGGFI++ FG F F L AI
Sbjct: 122 ALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAELFGIRTVFLLVGSFLFLAAIL 181
Query: 177 VLLVWREVGEIKVDKHEEHSGYRELLKP-----FFISACLSLFFISMAYSGVVTFLPALY 231
+ +E + + E+ +EL ++ L+ F I + + L ALY
Sbjct: 182 TICFIKE--DFQPVAKEKAIPTKELFTSVKYPYLLLNLFLTSFVIQFSAQSIGPIL-ALY 238
Query: 232 KVSGLGQS-----VFGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLL 286
V LGQ+ V GL + MG +S V G+ DK+G ++ V + YLL
Sbjct: 239 -VRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDKVGNHRLLVVAQFYSVIIYLLC 297
Query: 287 LKFKFPPNSYISAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQV 346
P + + G G G +P + + P + + +FF LG + G +
Sbjct: 298 ANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPKAGISRVFAFNQVFFYLGGVVGPM 357
Query: 347 GLGLVAQVRGYEGVFPVISI 366
VA GY VF S+
Sbjct: 358 AGSAVAGQFGYHAVFYATSL 377
>pir||H65004 hypothetical protein b2322 - Escherichia coli (strain K-12)
>gi|1684786|gb|AAB36528.1| (U76961) unknown [Escherichia
coli] >gi|1788662|gb|AAC75382.1| (AE000321) putative
transport protein [Escherichia coli K12]
>gi|1799715|dbj|BAA16179.1| (D90863) similar to
[SwissProt Accession Number P37621] [Escherichia coli]
Length = 392
Score = 80.0 bits (194), Expect = 4e-14
Identities = 90/376 (23%), Positives = 165/376 (42%), Gaps = 16/376 (4%)
Query: 4 NLWFLNFSTFFFFLGISILNPLISPYAI-TLGAKPFLVGVVAGVASGISLFSKLIGGYIG 62
+L+ + F+ F ++ + + P+I + LG +VG+ G+ ++ ++ G +
Sbjct: 16 SLFRIAFAVFLTYMTVGLPLPVIPLFVHHELGYGNTMVGIAVGIQFLATVLTRGYAGRLA 75
Query: 63 DK-GYRFHAMFLGNVLGIFSGLLYIASALSGS----IMVFALGRAVHGFAMGIFFPSSLS 117
D+ G + A+ G+ G L +A+ L S + +GR + GF +L+
Sbjct: 76 DQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVVGRLILGFGESQLLTGALT 135
Query: 118 SAVDLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFV 177
+ + G+ + W GM VG +G I +GF +++V VL
Sbjct: 136 WGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSHYGFAALAITTMVLPVLAWACN 195
Query: 178 LLVWREVGEIKVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFLPALYKVSGLG 237
V R+V + ++ S + KP L L + ++ + TF+ +LY S G
Sbjct: 196 GTV-RKVPALAGERPSLWSVVGLIWKP-----GLGLALQGVGFAVIGTFV-SLYFAS-KG 247
Query: 238 QSVFGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYI 297
++ G + G A MRV+ G D+ G + V V + + LLL + +
Sbjct: 248 WAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAPGAWVALA 307
Query: 298 SAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGM-LSGQVGLGLVAQVRG 356
AA++GAG L PAL + ++P ++R Y F D+ + +SG + G++A G
Sbjct: 308 GAALTGAGCSLIFPALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLA-GMLATTFG 366
Query: 357 YEGVFPVISILPLISI 372
Y VF +I ++ I
Sbjct: 367 YSSVFLAGAISAVLGI 382
>dbj|BAA75389.1| (AB013375) YhcA [Bacillus halodurans]
Length = 475
Score = 79.2 bits (192), Expect = 8e-14
Identities = 94/391 (24%), Positives = 158/391 (40%), Gaps = 44/391 (11%)
Query: 10 FSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIGDKGYRFH 69
F +F L S+LNP I A G V + + + GY+GDK +
Sbjct: 17 FGSFTMILNNSMLNPAIPQLMNVFEADAVATGWVITIFMVAMGMTMPLTGYLGDKIGKKE 76
Query: 70 AMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDLAPKGRVG 129
A LG LGIF L + ALS ++ + R + G G+ P S++ D P+ G
Sbjct: 77 AYILG--LGIFV-LGSLLGALSWNLPSLIVFRGLQGIGGGVMMPLSMTLIFDAFPRNERG 133
Query: 130 EALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWREV---GE 186
A G G+ + +GP +GGFI + + F +I F +LG I ++ ++ G+
Sbjct: 134 LATGVWGVASMMAPTIGPTLGGFIVETSNWKYLFLVNIPFGLLGIIAAVIYLPKIARSGQ 193
Query: 187 IKVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFLPALYKVSGLGQSVFGLYMM 246
IK+D+ F++ ++ + ++ L + + G+ ++
Sbjct: 194 IKLDR-------------------WGFLFVTAGVGSILLAFGRMSDLTHLTEWINGVLLL 234
Query: 247 IMGLASFFMRVVGGRSADKLGPIPVIRV----------GVS------GIFLAYLLLLK-F 289
+ L + V R+ L + + R+ G+S GIFL LLL + +
Sbjct: 235 LGALCLYVFVQVEKRAEQPLLDLSLFRIPAYSLSIWVAGISSIGLFAGIFLVPLLLQQVY 294
Query: 290 KFPPNSYISAAISGAGF-GLSLPALQYMALAKLPGKIRTMGSSIYTM-FFDLGMLSGQVG 347
+ P + A F GL++ M + P I T G I + F LG L + G
Sbjct: 295 DYGPIMTGLVFLPSALFTGLTMSIGGRMLDKRGPSGIMTAGMMIAAVGTFALGYLHLETG 354
Query: 348 LGLVAQVRGYEGVFPVISILPLISIAMAHIP 378
L + GV ++ +P + M IP
Sbjct: 355 LWYIFAWMAIRGVGMGLTTMPATTTGMNAIP 385
>dbj|BAB04273.1| (AP001508) multidrug resistance protein (efflux transporter)
[Bacillus halodurans]
Length = 474
Score = 79.2 bits (192), Expect = 8e-14
Identities = 94/391 (24%), Positives = 158/391 (40%), Gaps = 44/391 (11%)
Query: 10 FSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIGDKGYRFH 69
F +F L S+LNP I A G V + + + GY+GDK +
Sbjct: 16 FGSFTMILNNSMLNPAIPQLMNVFEADAVATGWVITIFMVAMGMTMPLTGYLGDKIGKKE 75
Query: 70 AMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDLAPKGRVG 129
A LG LGIF L + ALS ++ + R + G G+ P S++ D P+ G
Sbjct: 76 AYILG--LGIFV-LGSLLGALSWNLPSLIVFRGLQGIGGGVMMPLSMTLIFDAFPRNERG 132
Query: 130 EALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWREV---GE 186
A G G+ + +GP +GGFI + + F +I F +LG I ++ ++ G+
Sbjct: 133 LATGVWGVASMMAPTIGPTLGGFIVETSNWKYLFLVNIPFGLLGIIAAVIYLPKIARSGQ 192
Query: 187 IKVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFLPALYKVSGLGQSVFGLYMM 246
IK+D+ F++ ++ + ++ L + + G+ ++
Sbjct: 193 IKLDR-------------------WGFLFVTAGVGSILLAFGRMSDLTHLTEWINGVLLL 233
Query: 247 IMGLASFFMRVVGGRSADKLGPIPVIRV----------GVS------GIFLAYLLLLK-F 289
+ L + V R+ L + + R+ G+S GIFL LLL + +
Sbjct: 234 LGALCLYVFVQVEKRAEQPLLDLSLFRIPAYSLSIWVAGISSIGLFAGIFLVPLLLQQVY 293
Query: 290 KFPPNSYISAAISGAGF-GLSLPALQYMALAKLPGKIRTMGSSIYTM-FFDLGMLSGQVG 347
+ P + A F GL++ M + P I T G I + F LG L + G
Sbjct: 294 DYGPIMTGLVFLPSALFTGLTMSIGGRMLDKRGPSGIMTAGMMIAAVGTFALGYLHLETG 353
Query: 348 LGLVAQVRGYEGVFPVISILPLISIAMAHIP 378
L + GV ++ +P + M IP
Sbjct: 354 LWYIFAWMAIRGVGMGLTTMPATTTGMNAIP 384
>pir||E75048 multidrug resistance protein PAB0913 - Pyrococcus abyssi (strain
Orsay) >gi|5458795|emb|CAB50282.1| (AJ248287) multidrug
resistance protein [Pyrococcus abyssi]
Length = 410
Score = 78.4 bits (190), Expect = 1e-13
Identities = 91/379 (24%), Positives = 154/379 (40%), Gaps = 35/379 (9%)
Query: 1 MLKNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGY 60
M KN+ FF + P + Y +G FLVG+++ V + S + GY
Sbjct: 24 MRKNILMFAIGMFFADFAWGLGFPYLGVYMKLIGGTMFLVGLLSVVYNLTSTIFQYPFGY 83
Query: 61 IGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAV 120
+ DK + + +L SG Y AL S ++ RA G P+ +
Sbjct: 84 LSDKTGKRKPFIILGILA--SGTTYGLVALITSPILLLGLRAFQGALGASLAPAHSALIS 141
Query: 121 DLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLV 180
+L+P R+G G+ G + +LG + G GG+I G M F + + S++G +F+L +
Sbjct: 142 ELSP--RIGSMFGFFGFVENLGFMAGNFAGGYIVKTLGMKMMFIITSLVSLIGILFLLKI 199
Query: 181 WREVGE----------IKVDKHEEHSGYRELLKPFFISACLSLFFI----SMAYSGVVTF 226
+E G +K + + +E+ + L +F++ +M SG V
Sbjct: 200 -KERGRAKAGGDRLIIVKEGRESDRVELKEIAFKKLMKGRLGIFYVAVLLAMIASGAVYA 258
Query: 227 LPALYKVSGLGQSVFGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSG---IFLAY 283
++Y G+ G I L++ ++ GR DK G R+ + G F+ Y
Sbjct: 259 TVSVYFEEKFGEEFVGYLFGIDSLSAALSALIIGRLIDKYGEKLFFRLSLVGYIITFMGY 318
Query: 284 LLLLKFKFPPNSYISAAISGAGFGLSLPAL-----QYMALAKLPGKIRTMGSSIYTMFFD 338
L NS I A+ GL L Y+A ++P R G +
Sbjct: 319 AL-------ANSVIIMALISILSGLKWTMLTNSSSTYVA-RRVPTSERGQGMGLLNTMMT 370
Query: 339 LGMLSGQVGLGLVAQVRGY 357
LG + G + G++A G+
Sbjct: 371 LGWVIGPLIGGILADNFGF 389
>gb|AAF18272.1| (AF088897) transcriptional regulatory protein [Zymomonas mobilis]
Length = 406
Score = 77.3 bits (187), Expect = 3e-13
Identities = 90/383 (23%), Positives = 170/383 (43%), Gaps = 33/383 (8%)
Query: 16 FLGISILNPLISPYAITLGAKPFLVGVVAGVASGIS-----LFSKLIGGYIGDKGYRFHA 70
F+ +S+L P+ I+ G AG A IS L S L+ + KG+ +
Sbjct: 39 FMPVSLLTPVAKALQISEGQ--------AGQAISISGVFAVLTSLLMPSFT--KGFNRKS 88
Query: 71 MFLG-NVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDLAPKGRVG 129
+ LG + IFSGL+ + + + ++F +GRA+ G +G F+ S++ A+ L K V
Sbjct: 89 LLLGLTAMMIFSGLVV---SFAPNYLIFMVGRALIGVVIGGFWSMSVAIAMRLVEKHHVP 145
Query: 130 EALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWREVGEIKV 189
AL +L +V G F+ G+ AFF I ++ A+F+ L++ + +
Sbjct: 146 RALAIFNGGNALATVVAAPAGSFLGGLIGWRGAFFCIIPIAL--AVFIWLIY-SLPSLPD 202
Query: 190 DKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFL----PALYKVSGLGQSVFGLYM 245
+ E +LK + + ++++ G T P L ++ S L +
Sbjct: 203 ENKAERGTVLSILK--YPVVATGMMADTLSFMGQFTLFTNVRPFLETITDTDISTLSLIL 260
Query: 246 MIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAAI--SG 303
++MGLA F ++ G K G P++ +G + +F++ L +L F +++ +AAI
Sbjct: 261 LMMGLAGFIGTILIGTFL-KRGTYPIL-IG-TPLFMSVLAILLILFGKSAFFAAAILMLW 317
Query: 304 AGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRGYEGVFPV 363
F S P + LA+ + +G + L + + G++ +GY+ F
Sbjct: 318 GFFATSAPVGWWTWLAQTLPQKAEVGGGLMVAVIQLAITLARPVPGVIFDTKGYQATFIT 377
Query: 364 ISILPLISIAMAHIPLLWGRNDE 386
+ + +I+ A + R D+
Sbjct: 378 SAFILVIASLFAFLTAGIRRKDK 400
>gb|AAD10060.1| (AF113952) multidrug-efflux transporter [Campylobacter jejuni]
Length = 431
Score = 75.3 bits (182), Expect = 1e-12
Identities = 94/387 (24%), Positives = 167/387 (42%), Gaps = 25/387 (6%)
Query: 1 MLKNLWFLNFSTFFFFLGISILNPLISPYAITL-GAKPFLVGVVAGVASGISLFSKLIGG 59
ML N+ L+F F G+ I+ P++S YA+ L GA FLVG++ GV + + ++ G
Sbjct: 1 MLNNVLPLSFIVGTRFFGLFIVLPVLSLYALKLEGANEFLVGLLVGVYALTQMILQMPFG 60
Query: 60 YIGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGF-AMGIFFPSSLSS 118
+ DK R M +G ++ I L+ + + +I LGR + G A+G + +S
Sbjct: 61 ILSDKIGRKKTMLIGLIIFIIGSLI---CSFAENIYTMLLGRMLQGAGAIGAVATAMISD 117
Query: 119 AVDLAPKGRVGEALG-WRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFV 177
+ +G+ +G + G+ F+ ++ P +S K+G F S S+L I +
Sbjct: 118 FITEENRGKAMAVMGSFIGLSFAASMVISP----LMSAKWGLSSLFDLSAALSLLCIILL 173
Query: 178 LLVWREVGEIKVDKHEEHSGYRELLKPFFISAC-LSLFFISMAYSGVVTFLP-ALYKVSG 235
V + E K+ E + + L+K ++ L+ F M S +P L K G
Sbjct: 174 YTVVPK--ENKITHENEKTPFFHLIKQKNLALMNLTNFMQKMLMSIAFLSIPIILVKHLG 231
Query: 236 LGQSVFGLYMMIMGLASFFMRVVGGRSADKLG-PIPVIRVGVSGIFLAYLLLLKFKFPPN 294
+ +A F G +K G ++ +G+ L+YL
Sbjct: 232 FASDKLWIVYSASMVAGFIAMGFAGSLGEKRGLAKQILLLGIVFFILSYLFFAFSNSIDF 291
Query: 295 SYISAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQV 354
I+ I GF L P +Q + A K+ G+++ +F G +G G++
Sbjct: 292 FIIAVVIFFIGFNLHEPIMQ--SCASKFCKVHEKGAAL-GLFNAFGYGGSFIG-GIIG-- 345
Query: 355 RGYEGVFPVISILPLISIAMAHIPLLW 381
G+F + L L++I + + L+W
Sbjct: 346 ----GIFLHLDTLNLLAIILVILALIW 368
>pir||D81282 probable efflux protein Cj1375 [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6968809|emb|CAB73802.1|
(AL139078) putative efflux protein [Campylobacter
jejuni]
Length = 431
Score = 75.3 bits (182), Expect = 1e-12
Identities = 94/387 (24%), Positives = 167/387 (42%), Gaps = 25/387 (6%)
Query: 1 MLKNLWFLNFSTFFFFLGISILNPLISPYAITL-GAKPFLVGVVAGVASGISLFSKLIGG 59
ML N+ L+F F G+ I+ P++S YA+ L GA FLVG++ GV + + ++ G
Sbjct: 1 MLNNVLPLSFIVGTRFFGLFIVLPVLSLYALKLEGANEFLVGLLVGVYALTQMILQMPFG 60
Query: 60 YIGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGF-AMGIFFPSSLSS 118
+ DK R M +G ++ I L+ + + +I LGR + G A+G + +S
Sbjct: 61 ILSDKIGRKKTMLIGLIIFIIGSLI---CSFAENIYTMLLGRMLQGAGAIGAVATAMISD 117
Query: 119 AVDLAPKGRVGEALG-WRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFV 177
+ +G+ +G + G+ F+ ++ P +S K+G F S S+L I +
Sbjct: 118 FITEENRGKAMAVMGSFIGLSFAASMVISP----LMSAKWGLSSLFDLSAALSLLCIILL 173
Query: 178 LLVWREVGEIKVDKHEEHSGYRELLKPFFISAC-LSLFFISMAYSGVVTFLP-ALYKVSG 235
V + E K+ E + + L+K ++ L+ F M S +P L K G
Sbjct: 174 YTVVPK--ENKITHENEKTPFFHLIKQKNLALMNLTNFMQKMLMSIAFLSIPIILVKHLG 231
Query: 236 LGQSVFGLYMMIMGLASFFMRVVGGRSADKLG-PIPVIRVGVSGIFLAYLLLLKFKFPPN 294
+ +A F G +K G ++ +G+ L+YL
Sbjct: 232 FASDKLWIVYSASMVAGFIAMGFAGSLGEKKGLAKQILLLGIVFFILSYLFFAFSNSIDF 291
Query: 295 SYISAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQV 354
I+ I GF L P +Q + A K+ G+++ +F G +G G++
Sbjct: 292 FIIAVVIFFIGFNLHEPIMQ--SCASKFCKVHEKGAAL-GLFNAFGYGGSFIG-GIIG-- 345
Query: 355 RGYEGVFPVISILPLISIAMAHIPLLW 381
G+F + L L++I + + L+W
Sbjct: 346 ----GIFLHLDTLNLLAIILVILALIW 368
>dbj|BAB06311.1| (AP001516) unknown conserved protein [Bacillus halodurans]
Length = 409
Score = 74.9 bits (181), Expect = 1e-12
Identities = 92/383 (24%), Positives = 156/383 (40%), Gaps = 19/383 (4%)
Query: 3 KNLWFLNFSTFFFFLGISILNPLISPYAITLGAK-PFLVGVVAGVASGIS-----LFSKL 56
+NL+ L F ++++ P + Y LG P V + AG+ + LFS L
Sbjct: 6 RNLYILVVCQFLVVSAMTMIIPFLPLYLQELGVTDPSEVSLWAGIIFAANFLTAFLFSPL 65
Query: 57 IGGYIGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSL 116
G + + G + + GL A G + + L R ++G G F P+S+
Sbjct: 66 WSRLADRYGRKMMILRSGFGMALIIGLTGFAQ---GPLSLLCL-RLLNGVISG-FIPASI 120
Query: 117 SSAVDLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIF 176
PK + G ALG+ G I GP IGG ++ FG+ M FF + + + A+
Sbjct: 121 GLVATNTPKEKAGYALGFLQAGAVSGGICGPLIGGIMAQAFGYRMIFFLTGLCIFIAALV 180
Query: 177 VLLVWRE--VGEIKVDKHEEHSGYREL--LKPFFISACLSLFFISMAYSGVVTFLPALYK 232
VLL E K +K ++++ ++P F S + +F I A GV + +
Sbjct: 181 VLLFVNEQFTPNPKEEKTNTWGEFKKITAIRPIF-SLYVVVFLIQFAVMGVNPLISLFVE 239
Query: 233 --VSGLGQSVF-GLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKF 289
VSG+ ++F GL + G A+ + G+ +DK G V+ + G + +
Sbjct: 240 ELVSGVNVALFAGLAISATGFANMLSSMQLGKLSDKAGAHHVLFFCLLGTVIFMIPQAFV 299
Query: 290 KFPPNSYISAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLG 349
+ + G G LPA + P + + T LG + G G
Sbjct: 300 QQLWQLIVLRFFVGLSLGGLLPAANALVRMHAPKGMESRTYGFSTSALYLGNMVGPTVGG 359
Query: 350 LVAQVRGYEGVFPVISILPLISI 372
V G G+F + + L+++
Sbjct: 360 AVVATVGIRGLFLISAFTLLLTV 382
>pir||E75290 probable multidrug-efflux transporter - Deinococcus radiodurans
(strain R1) >gi|6460114|gb|AAF11851.1|AE002062_4
(AE002062) multidrug-efflux transporter, putative
[Deinococcus radiodurans]
Length = 410
Score = 73.0 bits (176), Expect = 6e-12
Identities = 85/360 (23%), Positives = 146/360 (39%), Gaps = 27/360 (7%)
Query: 6 WFLNFSTFFFFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIGDKG 65
W + + F+G+ +++P++ LGA P V ++ G+ L G IG K
Sbjct: 32 WAVTAACLIAFMGVGVVDPILPEIGRQLGATPTQVELLFTSYLGVMAVMTLFAGNIGAKL 91
Query: 66 YRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDLAPK 125
R +G LG+ + L A LSGSI A+ R G +F P++L + LA
Sbjct: 92 GRKRVALIG--LGLIA-LFAAACGLSGSIPALAVFRGGWGLGSALFTPTAL--VLLLALI 146
Query: 126 GRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWREVG 185
G +A+ LG +GP +GG + + FF + +L A+ + + +V
Sbjct: 147 GHAEKAIMRYEAAIGLGMSMGPLLGGVLG-SHSWRFPFFGAATLMLL-ALASVAAFVKVP 204
Query: 186 EIKVDKHEEHSGYRELLKPFFISACLSLFFISMAYSGVVTFLPALYKVSGLGQSVFGLYM 245
E K +R +P F++ L+ + ++ + P +S L
Sbjct: 205 ESKEPPRPIGDVFRAYTRPAFLAVGLTGLLYYFGFFLLLGYTPLFLHLSTLN-------- 256
Query: 246 MIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAAI---- 301
+GL F ++ G + KL + + RV S + + L L F + A+
Sbjct: 257 --LGLMFFGWGILLGLGSTKLAEVLLRRVKASNVVMGALAGLTIIFALLGFAPFAVGVKV 314
Query: 302 -----SGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRG 356
SG FGL L +++ ++ R +S Y LG + V GL+A+ G
Sbjct: 315 GLVVLSGVLFGLMNATLTTLSV-EVSHMPRPTATSAYNFLRWLGAAAAPVSSGLIAEHLG 373
>sp|P25744|YCEE_ECOLI HYPOTHETICAL 43.9 KDA PROTEIN IN MSYB-HTRB INTERGENIC REGION (ORF1)
>gi|95972|pir||B42290 probable membrane protein b1053 -
Escherichia coli >gi|42029|emb|CAA42562.1| (X59939) ORF1
[Escherichia coli] >gi|1787291|gb|AAC74137.1| (AE000206)
putative transport protein [Escherichia coli K12]
>gi|4062627|dbj|BAA35851.1| (D90742) Probable integral
membrane protein. [Escherichia coli]
>gi|4062636|dbj|BAA35862.1| (D90743) Probable integral
membrane protein. [Escherichia coli]
Length = 408
Score = 71.8 bits (173), Expect = 1e-11
Identities = 88/378 (23%), Positives = 156/378 (40%), Gaps = 26/378 (6%)
Query: 3 KNLWFLNFSTFFFFLGISILNPLISPYAITLGAKPF-LVGVVAGVASGIS-LFSKLI--- 57
+NL F S++ P + Y LG + + +G+ I+ LFS +
Sbjct: 14 RNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPF 73
Query: 58 -GGYIGDKGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSL 116
GG KG + M L + LG+ G++ + L+ +I F + RA+ G +G F P++
Sbjct: 74 WGGLADRKGRKL--MLLRSALGM--GIVMVLMGLAQNIWQFLILRALLGL-LGGFVPNAN 128
Query: 117 SSAVDLAPKGRVGEALGWRGMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIF 176
+ P+ + G ALG G ++GP GG ++D +G FF + +L
Sbjct: 129 ALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFV 188
Query: 177 VLLVWREVGEIKVDKHEEH--SGYRELLKPFFISACLSLFFISMAYSGVVTFLPALY--- 231
L RE + K H L P + + I +G + + LY
Sbjct: 189 TLFCIREKFQPVSKKEMLHMREVVTSLKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRE 248
Query: 232 ---KVSGLGQSVFGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLK 288
VS + + G+ + G+A+ G+ D++GP ++ ++ + + LLL+
Sbjct: 249 LAGNVSNVA-FISGMIASVPGVAALLSAPRLGKLGDRIGPEKIL---ITALIFSVLLLIP 304
Query: 289 FKF---PPNSYISAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQ 345
+ P I + GA G LPA+Q + + +I S F D+G ++G
Sbjct: 305 MSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGP 364
Query: 346 VGLGLVAQVRGYEGVFPV 363
+ ++ G+ VF V
Sbjct: 365 LMGAAISANYGFRAVFLV 382
>pir||T45544 hypothetical protein 3 [imported] - Klebsiella pneumoniae
transposon Tn5711 >gi|3758825|emb|CAA09859.1| (AJ011907)
hypothetical protein [Klebsiella pneumoniae]
Length = 404
Score = 70.2 bits (169), Expect = 4e-11
Identities = 79/375 (21%), Positives = 153/375 (40%), Gaps = 12/375 (3%)
Query: 5 LWFLNFSTFFFFLGISILNPLISPY-AITLGAKPFLVGVVAGVASGISLFSKLIGGYIGD 63
+W + + + +++ L+ + A TLGA ++G++ G+A +L K+ G I D
Sbjct: 15 VWVVGCVSLLMDISSEMIHSLLPLFMATTLGASVLVIGLIEGLAEATALIVKVFSGVISD 74
Query: 64 -KGYRFHAMFLGNVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDL 122
G R LG LG S L+ ++ SG ++ R GI + D+
Sbjct: 75 WLGKRKGLALLGYGLGALSKPLFAIASSSGMVLT---ARLTDRLGKGIRGRPRDALVADV 131
Query: 123 APKGRVGEALGWRGMMFSLGNIVGP--AIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLV 180
P G A G R + ++G +GP A+G + + F F+ +++ ++ + L
Sbjct: 132 TPPELRGAAFGLRQSLDTIGAFLGPLLAVGLMLLWQDDFRAIFWVAVIPGLMAVALLFLG 191
Query: 181 WREVGEIKVDKHE---EHSGYRELLKPFFISACLSLFFISMAYSGVVTFLPALYKVSGLG 237
E V K + + L + + L F +S FL + +
Sbjct: 192 LHEPRTAVVHKRTNPVSRANLKRLGQSTWWVIALGGIFTLARFS--EAFLVLRAQEVHIP 249
Query: 238 QSVFGLYMMIMGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYI 297
++ L M+ M L F G+ AD++ ++++G+ + +A ++L I
Sbjct: 250 LALIPLVMVAMNLLYSFSAYPFGKLADRMSHRHLLQLGLVVLVVADIVLALSTHWVGVLI 309
Query: 298 SAAISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRGY 357
A+ G G++ L M P +R ++++ + +L G GL+ G
Sbjct: 310 GVALWGVHMGMTQGLLAAMIADSSPADLRGTAYGLFSLVSGVALLLASAGAGLLWTTWGS 369
Query: 358 EGVFPVISILPLISI 372
E F + + LI++
Sbjct: 370 ESTFIAGAAICLITL 384
>pir||C82644 transcription regulator XF1749 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9106819|gb|AAF84558.1|AE003997_14
(AE003997) transcriptional regulator [Xylella
fastidiosa]
Length = 409
Score = 70.2 bits (169), Expect = 4e-11
Identities = 79/360 (21%), Positives = 146/360 (39%), Gaps = 21/360 (5%)
Query: 16 FLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIGDKGYRFHAMFLGN 75
FL +S+L P+ +T G + + A SLF + G + K + LG
Sbjct: 44 FLPVSLLTPMARDLQVTEGMTGQGIAISGAFAVLTSLFISALAGSLNRK-----TLLLGL 98
Query: 76 VLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDLAPKGRVGEALGWR 135
L + G+ AL+ + ++ LGRA+ G +G F+ S ++A+ + PK V AL
Sbjct: 99 TLAM--GVSGAIVALAPNYAIYMLGRALIGVVVGGFWSMSAATAIRMVPKRDVPRALAIV 156
Query: 136 GMMFSLGNIVGPAIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWREVGEIKVDKHEEH 195
+L +V +G ++S G+ AF + S+ + L W+ +
Sbjct: 157 NGGNALATVVAAPMGAYLSTVIGWRGAFLCLVPVSL-----IALAWQWKTLPSMPAAARA 211
Query: 196 SGYRELLK-------PFFISACLSLFFISMAYSGVVTFL-PALYKVSGLGQSVFGLYMMI 247
G ++ K P + L+ + M G+ T++ P L V+ + + L++++
Sbjct: 212 PGIGQVFKVFTLFKHPGVVVGMLASSLLFMGQFGLFTYVRPFLETVTNVHGATISLFLLV 271
Query: 248 MGLASFFMRVVGGRSADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAAISGAGFG 307
+G A F V+ GR + +I + V A L+ + A+ G G
Sbjct: 272 LGAAGFIGTVLIGRVLQRSFYQTMIVIPVLMALTALALIAFGSSVAIVLVLLALWGL-TG 330
Query: 308 LSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRGYEGVFPVISIL 367
S P + +AK+ K G ++ + + G G++ GY F ++L
Sbjct: 331 TSAPVGWWAWIAKVFPKDAEAGGGLFVAVVQMSIALGSTVGGILFDHSGYRTTFVASAVL 390
>dbj|BAB05798.1| (AP001514) unknown conserved protein in others [Bacillus
halodurans]
Length = 392
Score = 69.9 bits (168), Expect = 5e-11
Identities = 82/376 (21%), Positives = 150/376 (39%), Gaps = 25/376 (6%)
Query: 15 FFLGISILNPLISPYAITLGAKPFLVGVVAGVASGISLFSKLIGGYIGDKGYRFHAMFLG 74
+F SILN +I + TLGA +G++ G ++F + G I K + +
Sbjct: 20 YFSANSILNVIIPLQSGTLGASNTTIGIIMGAYLFTTMFFRPWAGQIIQKHGPIKVLRII 79
Query: 75 NVLGIFSGLLYIASALSGSIMVFALGRAVHGFAMGIFFPSSLSSAVDLAPKGRVGEALGW 134
++ + +LY + L G + R + G + F + +D P+ + +
Sbjct: 80 LMINGVALILYTFTGLGG----YLAARMLQGVSTAFFSMALQIGIIDALPEKDRSQGISL 135
Query: 135 RGMMFSLGNIVGP--AIGGFISDKFGFGMAFFSSIVFSVLGAIFVLLVWREVGEIKVDKH 192
+ + I+GP A+G + +D + +I S + + + + K
Sbjct: 136 YSLFSYIPGIIGPMLALGIWQTDDMSYFTFVMIAIAASTILFGYSAKMDNDQSAANHIKQ 195
Query: 193 EEH--SGYRELLKPFFISACLSLFFI-SMAYSGVVTFLPALYKVSGLGQSVFGLYMMIMG 249
E+ + +L+K F+ C L + S+ + V TF+P LY V L G+Y+MIM
Sbjct: 196 RENIFKSFNQLVKNPFLFKCSVLMLVASIIFGAVTTFIP-LYAVQ-LEDGNAGIYLMIMA 253
Query: 250 LASFFMRVVGGR---------SADKLGPIPVIRVGVSGIFLAYLLLLKFKFPPNSYISAA 300
F R + S +G + ++ +G + + + F Y+ A
Sbjct: 254 ATVVFARFTLRKKIPSDGKWHSTFMMGTMFLLAIGTQCVSFSITGGVAF-----FYLGAI 308
Query: 301 ISGAGFGLSLPALQYMALAKLPGKIRTMGSSIYTMFFDLGMLSGQVGLGLVAQVRGYEGV 360
G + P L LP R + ++ DLG+ G V +G VA + Y +
Sbjct: 309 FIGIAQAIIYPTLTTYLTFVLPQTNRNVLIGLFIAMADLGVSLGGVIMGPVADLFSYSSM 368
Query: 361 FPVISILPLISIAMAH 376
+ V S+L + AH
Sbjct: 369 YMVCSVLGAAMVLFAH 384
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.329 0.147 0.444
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 139669464
Number of Sequences: 2977
Number of extensions: 5932416
Number of successful extensions: 21154
Number of sequences better than 1.0e-10: 23
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 21098
Number of HSP's gapped (non-prelim): 36
length of query: 387
length of database: 189,106,746
effective HSP length: 51
effective length of query: 336
effective length of database: 158,583,909
effective search space: 53284193424
effective search space used: 53284193424
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.8 bits)
S2: 166 (69.1 bits)