BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0151 (purF) DE:amidophosphoribosyltransferase (purF)
(447 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75212 amidophosphoribosyltransferase (EC 2.4.2.14) PAB0151... 905 0.0
sp|O57979|PUR1_PYRHO AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 746 0.0
sp|Q57657|PUR1_METJA PROBABLE AMIDOPHOSPHORIBOSYLTRANSFERASE (GL... 420 e-116
gi|11498479 amidophosphoribosyltransferase (purF) [Archaeoglobus... 419 e-116
dbj|BAB04349.1| (AP001509) phosphoribosylpyrophosphate amidotran... 400 e-110
sp|O26742|PUR1_METTH AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 398 e-110
sp|P00497|PUR1_BACSU AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 393 e-108
pdb|1AO0|A Chain A, Glutamine Phosphoribosylpyrophosphate (Prpp)... 386 e-106
gb|AAD00109.1| (U64826) glutamine phosphoribosylpyrophosphate am... 386 e-106
pdb|1GPH|1 Chain 1, Glutamine Phosphoribosylpyrophosphate (Prpp)... 385 e-106
gb|AAD26498.1|AC007195_12 (AC007195) amidophosphoribosyltransfer... 382 e-105
pir||S52622 amidophosphoribosyltransferase (EC 2.4.2.14) 1 precu... 379 e-104
pir||A72277 amidophosphoribosyltransferase (EC 2.4.2.14) TM1247 ... 379 e-104
emb|CAC12366.1| (AL445067) probable amidophosphoribosyltransfera... 378 e-104
pir||A75545 amidophosphoribosyltransferase (EC 2.4.2.14) DR0220 ... 377 e-103
pir||S52621 amidophosphoribosyltransferase - Arabidopsis thalian... 375 e-103
pir||T05294 amidophosphoribosyltransferase (EC 2.4.2.14) 2 precu... 375 e-103
pir||T51702 amidophosphoribosyltransferase (EC 2.4.2.14) [import... 373 e-102
sp|O06626|PUR1_MYCTU AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 364 e-99
gb|AAC24007.1| (AF071862) phosphoribosylpyrophosphate amidotrans... 364 1e-99
pir||T06087 amidophosphoribosyltransferase (EC 2.4.2.14) T9A14.1... 363 3e-99
emb|CAB96578.1| (AJ278609) phosphoribosyl pyrophosphate amidotra... 362 4e-99
sp|P52418|PUR1_SOYBN AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 360 1e-98
sp|Q55038|PUR1_SYNP7 AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 360 3e-98
gb|AAG19793.1| (AE005064) amidophosphoribosyl-pyrophosphate amid... 360 3e-98
sp|Q55621|PUR1_SYNY3 AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 355 6e-97
sp|P52419|PUR1_VIGAC AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 351 7e-96
sp|Q50028|PUR1_MYCLE AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 350 2e-95
pir||A70401 amidophosphoribosyltransferase (EC 2.4.2.14) purF [s... 350 2e-95
gb|AAF18277.1| (AF088897) amidophosphoribosyltransferase [Zymomo... 349 3e-95
dbj|BAA89439.1| (AB003158) amidophosphoribosyl transferase [Cory... 348 6e-95
emb|CAA62633.1| (X91252) amidophosphoribosyltransferase [Coryneb... 346 2e-94
sp|P28173|PUR1_CHICK AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 343 2e-93
gb|AAF54163.1| (AE003676) Prat gene product [Drosophila melanoga... 342 5e-93
gb|AAK40941.1| Amidophosphoribosyltransferase (glutamine phospho... 340 1e-92
emb|CAB57669.1| (Y18930) amidophosphoribosyltransferase (ATASE),... 340 1e-92
sp|Q27601|PUR1_DROME AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 339 3e-92
gb|AAF50639.2| (AE003561) CG10078 gene product [alt 1] [Drosophi... 329 4e-89
sp|P77935|PUR1_RHIET AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 324 9e-88
gi|4505979 phosphoribosyl pyrophosphate amidotransferase [Homo s... 324 1e-87
pir||A53342 amidophosphoribosyltransferase (EC 2.4.2.14) precurs... 324 2e-87
sp|P35433|PUR1_RAT AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLU... 322 5e-87
pir||C81438 amidophosphoribosyltransferase (EC 2.4.2.14) Cj0196c... 320 2e-86
sp|P43854|PUR1_HAEIN AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE P... 303 3e-81
pir||C82618 amidophosphoribosyltransferase XF1949 [imported] - X... 301 1e-80
pir||G83256 amidophosphoribosyltransferase PA3108 [imported] - P... 298 1e-79
gb|AAF68406.1|AF237920_1 (AF237920) amidophosphoribosyltransfera... 295 6e-79
pir||A81170 amidophosphoribosyltransferase (EC 2.4.2.14) NMB0690... 293 4e-78
pir||G81935 amidophosphoribosyltransferase (EC 2.4.2.14) NMA0892... 289 3e-77
pir||T24422 amidophosphoribosyltransferase (EC 2.4.2.14) [simila... 288 7e-77
pir||F82253 amidophosphoribosyltransferase VC1004 [imported] - V... 282 7e-75
sp|P00496|PUR1_ECOLI AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE P... 277 2e-73
pdb|1ECF|B Chain B, Escherichia Coli Glutamine Phosphoribosylpyr... 277 2e-73
emb|CAA30971.1| (X12423) amidophosphoribosyltransferase [Escheri... 275 7e-73
sp|P41390|PUR1_SCHPO AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE P... 264 1e-69
emb|CAA23613.1| (V00322) reading frame purF [Escherichia coli] >... 259 6e-68
gi|6323958 phosphoribosylpyrophosphate amidotransferase; Ade4p [... 259 6e-68
sp|Q12698|PUR1_SACKL AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE P... 258 1e-67
gb|AAA24453.1| (M26893) amidophosphoribosyltransferase (EC 2.4.2... 257 2e-67
gb|AAA34403.1| (K02203) amidophosphoribosyltransferase [Saccharo... 252 6e-66
gi|11435995 phosphoribosyl pyrophosphate amidotransferase [Homo ... 250 2e-65
gb|AAK40942.1| Amidophosphoribosyltransferase (glutamine phospho... 215 1e-54
emb|CAB57667.1| (Y18930) amidophosphoribosyltransferase (ATASE),... 215 1e-54
dbj|BAA16166.1| (D90863) AMIDOPHOSPHORIBOSYLTRANSFERASE (EC 2.4.... 153 3e-36
dbj|BAB13799.1| (AB031231) glutamine phosphoribosylpyrophosphate... 153 4e-36
sp|Q51342|PUR1_PSEAE AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE P... 152 1e-35
sp|P35853|PUR1_LACCA AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (G... 126 4e-28
gb|AAK40710.1| Glutamine-fructose-6-phosphate transaminase (isom... 93 7e-18
sp|Q56275|GLMS_THIFE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 91 2e-17
sp|O84823|GLMS_CHLTR GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 91 2e-17
pir||D71248 glutamine--fructose-6-phosphate transaminase (isomer... 89 1e-16
sp|O57981|GLMS_PYRHO GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 88 2e-16
pir||H82022 glutamine--fructose-6-phosphate transaminase (isomer... 87 3e-16
pir||B81246 glutamine--fructose-6-phosphate transaminase (isomer... 87 4e-16
pir||G75092 asparagine synthase (glutamine-hydrolyzing) (EC 6.3.... 86 7e-16
sp|O86781|GLMS_STRCO GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 86 9e-16
pir||B81729 glutamine--fructose-6-phosphate transaminase (isomer... 85 1e-15
sp|O26273|GLMS_METTH GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 85 2e-15
gi|9631669 PBCV-1 glucosamine synthetase [Paramecium bursaria Ch... 84 3e-15
sp|Q56213|GLMS_THETH GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 83 8e-15
pir||F82951 glucosamine--fructose-6-phosphate aminotransferase P... 82 2e-14
pir||F75212 glutamine--fructose-6-phosphate transaminase (isomer... 81 2e-14
sp|O68956|GLMS_MYCSM GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 81 3e-14
pir||A72592 glutamine--fructose-6-phosphate transaminase (isomer... 80 4e-14
emb|CAB87226.1| (AL163641) glucosamine-fructose-6-phosphate amin... 80 4e-14
sp|Q9YCQ6|GLMS_AERPE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 80 4e-14
sp|P25195|NODM_RHIME GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 80 7e-14
sp|P72720|GLMS_SYNY3 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 80 7e-14
sp|Q9WXZ5|GLMS_THEMA GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 79 1e-13
gb|AAF09884.1|AE001891_3 (AE001891) glucosamine--fructose-6-phos... 79 1e-13
pir||A75536 glutamine--fructose-6-phosphate transaminase (isomer... 79 1e-13
pir||A82844 glucosamine--fructose-6-phosphate aminotransferase X... 78 2e-13
sp|P08633|NODM_RHILV GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 78 3e-13
sp|Q9Z6U0|GLMS_CHLPN GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 76 1e-12
pir||B81528 glutamine--fructose-6-phosphate transaminase (isomer... 76 1e-12
sp|O68280|GLMS_NOSS9 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 75 2e-12
sp|P39754|GLMS_BACSU GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 74 4e-12
sp|O06253|GLMS_MYCTU GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 73 5e-12
emb|CAA04007.1| (AJ000333) glmS [Mycobacterium tuberculosis] 73 5e-12
sp|O26060|GLMS_HELPY GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 73 5e-12
sp|P40831|GLMS_MYCLE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 73 7e-12
emb|CAA25785.1| (X01631) gluS protein [Escherichia coli] 72 1e-11
gb|AAA62080.1| (L10328) glutamine amidotransferase [Escherichia ... 72 1e-11
sp|P17169|GLMS_ECOLI GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 72 1e-11
pdb|1GDO|B Chain B, Glutaminase Domain Of Glucosamine 6-Phosphat... 72 1e-11
sp|O66648|GLMS_AQUAE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 72 1e-11
sp|Q9ZJ94|GLMS_HELPJ GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRAN... 71 2e-11
dbj|BAB03987.1| (AP001507) L-glutamine-D-fructose-6-phosphate am... 71 2e-11
gb|AAG18649.1| (AE004970) glutamine-fructose-6-phosphate transam... 71 2e-11
pir||C81281 glutamine--fructose-6-phosphate transaminase (isomer... 71 3e-11
pir||G71050 asparagine synthase (glutamine-hydrolyzing) (EC 6.3.... 70 4e-11
>pir||B75212 amidophosphoribosyltransferase (EC 2.4.2.14) PAB0151 precursor
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5457654|emb|CAB49145.1| (AJ248283)
amidophosphoribosyltransferase (purF) [Pyrococcus
abyssi]
Length = 447
Score = 905 bits (2313), Expect = 0.0
Identities = 447/447 (100%), Positives = 447/447 (100%)
Query: 1 MAKVRGMREKCGIFGVSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSE 60
MAKVRGMREKCGIFGVSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSE
Sbjct: 1 MAKVRGMREKCGIFGVSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSE 60
Query: 61 VFDENSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYE 120
VFDENSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYE
Sbjct: 61 VFDENSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYE 120
Query: 121 GMGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDP 180
GMGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDP
Sbjct: 121 GMGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDP 180
Query: 181 VGFRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVIDGESYESKVLAREKHAYCV 240
VGFRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVIDGESYESKVLAREKHAYCV
Sbjct: 181 VGFRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVIDGESYESKVLAREKHAYCV 240
Query: 241 FEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGI 300
FEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGI
Sbjct: 241 FEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGI 300
Query: 301 PYMEGLIKNRYIGRTFIMPSGRGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVK 360
PYMEGLIKNRYIGRTFIMPSGRGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVK
Sbjct: 301 PYMEGLIKNRYIGRTFIMPSGRGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVK 360
Query: 361 MLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIE 420
MLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIE
Sbjct: 361 MLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIE 420
Query: 421 GLKRAVGTKNLCMACLTGEYPEWAFNF 447
GLKRAVGTKNLCMACLTGEYPEWAFNF
Sbjct: 421 GLKRAVGTKNLCMACLTGEYPEWAFNF 447
>sp|O57979|PUR1_PYRHO AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|7433951|pir||A71248
amidophosphoribosyltransferase (EC 2.4.2.14) PH0240
precursor [similarity] - Pyrococcus horikoshii
>gi|3256629|dbj|BAA29312.1| (AP000001) 449aa long
hypothetical amidophosphoribosyltransferase [Pyrococcus
horikoshii]
Length = 449
Score = 746 bits (1904), Expect = 0.0
Identities = 358/442 (80%), Positives = 396/442 (88%), Gaps = 1/442 (0%)
Query: 7 MREKCGIFGVSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSEVFDENS 66
M+EKCGIFG S+DA +KTYYGL+ALQHRGQEGAGISVW+G IRT+KGHGLVSEVF S
Sbjct: 6 MKEKCGIFGAYSQDATKKTYYGLMALQHRGQEGAGISVWDGDIRTVKGHGLVSEVFKGGS 65
Query: 67 LN-LASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIK 125
+ L N IGHVRYSTSGSLSEVQPLEV CCGY+++IAHNGTLTNF+PLRR YE G K
Sbjct: 66 IRRLNGNPVIGHVRYSTSGSLSEVQPLEVECCGYKVSIAHNGTLTNFLPLRRFYESRGFK 125
Query: 126 FHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFRP 185
F SS+DTEVI +SFLNHYS++KDEFEAM RVFEEVKGAYS+L+LF+GK+IA RDPVGFRP
Sbjct: 126 FRSSIDTEVIAVSFLNHYSELKDEFEAMSRVFEEVKGAYSVLMLFNGKLIAVRDPVGFRP 185
Query: 186 LVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVIDGESYESKVLAREKHAYCVFEYIY 245
L FG GDGYYF+SEDSALRMF RDV PGEV V+ ESK++ R +HAYCVFEYIY
Sbjct: 186 LSFGAGDGYYFSSEDSALRMFCTNIRDVSPGEVIVVKDGEAESKIVGRSEHAYCVFEYIY 245
Query: 246 FARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEG 305
FARPDS +NGI+VY ARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEG
Sbjct: 246 FARPDSIINGISVYWARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEG 305
Query: 306 LIKNRYIGRTFIMPSGRGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDA 365
LIKNRYIGRTFIMPSGR +KV+LKLSPV+EV+ G+R+VLVDDSIVRGTTM IVKMLRDA
Sbjct: 306 LIKNRYIGRTFIMPSGREIKVRLKLSPVKEVIKGRRIVLVDDSIVRGTTMKNIVKMLRDA 365
Query: 366 GAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRA 425
GAREVHVRIASPPIRYPCYMGIDIPTRHELIAAW+SIE+I+KEIGADSLAYLS+EGLKRA
Sbjct: 366 GAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWKSIEEIKKEIGADSLAYLSVEGLKRA 425
Query: 426 VGTKNLCMACLTGEYPEWAFNF 447
+GT LCMACLTG YPEWAF+F
Sbjct: 426 IGTDKLCMACLTGNYPEWAFDF 447
>sp|Q57657|PUR1_METJA PROBABLE AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|2127755|pir||E64325
amidophosphoribosyltransferase (EC 2.4.2.14) MJ0204
[similarity] - Methanococcus jannaschii
>gi|1590947|gb|AAB98188.1| (U67476)
amidophosphoribosyltransferase (purF) [Methanococcus
jannaschii]
Length = 471
Score = 420 bits (1067), Expect = e-116
Identities = 236/458 (51%), Positives = 303/458 (65%), Gaps = 27/458 (5%)
Query: 11 CGIFGVSSEDAV---RKTYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEVFDENS 66
CGIFG+ S + + +K YYGL ALQHRGQEGAGI+ +G+ I K GLV++VF +
Sbjct: 2 CGIFGIYSYERLNVAKKIYYGLFALQHRGQEGAGIATSDGKNIHYYKNIGLVTDVFKNET 61
Query: 67 L-NLASNIAIGHVRYSTSG--SLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMG 123
L NL I IGHVRYST+G ++ QP V+ +AIAHNG L N LRR E G
Sbjct: 62 LQNLFGYIGIGHVRYSTTGGKAVENCQPFVVKSSFGNIAIAHNGDLVNSDELRRELEMKG 121
Query: 124 IKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGF 183
F SS D+EVI + + D+ EA++ +++ GAYS+LI+F+ +IA RDP GF
Sbjct: 122 HIFTSSTDSEVIAQLLVRELLKTSDKIEAIKNTLKKLVGAYSLLIMFNDSLIAVRDPWGF 181
Query: 184 RPLVFGEGDG-YYFASEDSALRMFGLE-TRDVLPGEVFVI-DGESYESKV---------- 230
+PL G + Y +SED AL E +D+ PGE+ I DGE K+
Sbjct: 182 KPLCIGRDESNIYISSEDCALTTLDAEFVKDIEPGEIIEIKDGEIISHKLDYGVSEYNPV 241
Query: 231 -----LAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPD 285
A C+FEY+YFARPDST++GI+VY R R+G LA+E P + DVV +PD
Sbjct: 242 NVDVPCIYRGAATCMFEYVYFARPDSTIDGISVYKVRKRIGKILAKEHPVDADVVSPIPD 301
Query: 286 SGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVV 343
SG T ALGF+ ESGIPY EGLIKNRY+GRTFI+PS R L V+LKLSPV+ V+ GKRVV
Sbjct: 302 SGVTFALGFSEESGIPYYEGLIKNRYVGRTFILPSQNERELAVRLKLSPVKSVLEGKRVV 361
Query: 344 LVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIE 403
LVDDSIVRGTT RIV M+R AGA+EVH+RI P I PCY GID+ T+ ELIA+ ++ E
Sbjct: 362 LVDDSIVRGTTSRRIVNMVRKAGAKEVHLRIGCPKIISPCYYGIDMATKKELIASNKTEE 421
Query: 404 DIRKEIGADSLAYLSIEGLKRAVGTKNLCMACLTGEYP 441
+I K IG DS+ YLS+EGL +A+G K+LC+AC+TG+YP
Sbjct: 422 EIGKAIGVDSIGYLSLEGLVKAIGRKDLCLACVTGKYP 459
>gi|11498479 amidophosphoribosyltransferase (purF) [Archaeoglobus fulgidus]
>gi|6647705|sp|O29388|PUR1_ARCFU PROBABLE
AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|7433953|pir||A69359
amidophosphoribosyltransferase (EC 2.4.2.14) AF0873
[similarity] - Archaeoglobus fulgidus
>gi|2649729|gb|AAB90366.1| (AE001044)
amidophosphoribosyltransferase (purF) [Archaeoglobus
fulgidus]
Length = 457
Score = 419 bits (1065), Expect = e-116
Identities = 235/446 (52%), Positives = 294/446 (65%), Gaps = 15/446 (3%)
Query: 11 CGIFGVSSED---AVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSEVF-DENS 66
CG+ G+ D A R YY L +LQHRGQE AGI+ ++ IR +G GLV+EVF DE+
Sbjct: 2 CGVVGIYHPDGELAPRLAYYSLFSLQHRGQESAGIASFDNHIRQKRGMGLVTEVFNDEDF 61
Query: 67 LNLASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
LA IGHVRYST+G L QP V+ +A+AHNG L N+ LR E G
Sbjct: 62 ELLAGKSVIGHVRYSTTGRSRLENAQPFVVKSKAGYIAVAHNGNLVNYSQLRNELENEGR 121
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFR 184
F + DTEVI + D A+ R+ E + G+Y++ +L D +I RDP+GF+
Sbjct: 122 VFTTDSDTEVISQLLSKFLIEEGDIINALERLNESLVGSYTMTMLVDDAVIGYRDPLGFK 181
Query: 185 PLVFGE-GDGYYFASEDSALRMFGLE-TRDVLPGEVFVI-DGESYESKVLAREKHAYCVF 241
PL G DGY SE A+ G E RDV PG+ +I DGE K+ E+ A C+F
Sbjct: 182 PLCVGRIDDGYVICSESCAIDALGGEFIRDVQPGKAAIIKDGELEFVKIAKSERRAVCIF 241
Query: 242 EYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIP 301
EYIYFARPDS ++GI+VY AR MG LARESP E D V AVPDSG TAA+G+A ESG+P
Sbjct: 242 EYIYFARPDSIIDGISVYKARSEMGKVLARESPVEADFVSAVPDSGITAAIGYAQESGLP 301
Query: 302 YMEGLIKNRYIGRTFIMP--SGRGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIV 359
Y EGLIKNRY+GRTFIMP S R V+LK++ VRE V G+RVVLVDDSIVRGTT RIV
Sbjct: 302 YFEGLIKNRYVGRTFIMPVQSLRETSVRLKVNVVRENVRGRRVVLVDDSIVRGTTSRRIV 361
Query: 360 KMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSI 419
+M++DAGA+EVH+RI SPPI PCY GID+ +R ELIAA ++E+I + G DSLAYLS+
Sbjct: 362 QMIKDAGAKEVHMRIGSPPIIAPCYFGIDMKSREELIAASHTVEEIGRIFGTDSLAYLSL 421
Query: 420 EGL----KRAVGTKNLCMACLTGEYP 441
EGL +RA G + C+ACLT +YP
Sbjct: 422 EGLLEAVRRAGGKRGYCLACLTSKYP 447
>dbj|BAB04349.1| (AP001509) phosphoribosylpyrophosphate amidotransferase [Bacillus
halodurans]
Length = 473
Score = 400 bits (1017), Expect = e-110
Identities = 224/457 (49%), Positives = 305/457 (66%), Gaps = 20/457 (4%)
Query: 2 AKVRGMREKCGIFGV-SSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTI-KGHGLVS 59
A+++G+ E+CG+F + EDA + YYGL +LQHRGQEGAGI V +G ++ KG GLV+
Sbjct: 3 AEIKGLNEECGVFAIWGHEDAAQVAYYGLHSLQHRGQEGAGIVVTDGHQLSVHKGLGLVN 62
Query: 60 EVFDENSLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLR 116
+VF+ + + L A+GHVRY+T+G + VQPL R LAIAHNG L N L+
Sbjct: 63 DVFNPDIFDSLKGKAAVGHVRYATAGGGGYANVQPLVFRSQIGSLAIAHNGNLVNANHLK 122
Query: 117 RLYEGMGIKFHSSVDTEVIG-ISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKII 175
E G F S+ DTEV+ + + Y ++++ ++ + +KGAY+ ++ + +++
Sbjct: 123 NQLENQGSIFQSTSDTEVLAHLIKRSGYHHIREQLKSSLSM---LKGAYAFAVMTERELM 179
Query: 176 AARDPVGFRPLVFGE-GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAR 233
A DP G RPL G G+ Y ASE A + G E R+V PGE+ I+ + S+
Sbjct: 180 VALDPNGLRPLSIGRLGEAYVVASETCAFDVIGAEYVREVEPGELVTINDDGLTSERFVG 239
Query: 234 EK-HAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAAL 292
E A C EY+YFARPDS ++ INV+ AR +G +LA E+P E DVV VPDS +AA+
Sbjct: 240 EAARAICSMEYVYFARPDSNVDTINVHTARKNLGKQLAIEAPVEADVVTGVPDSSISAAI 299
Query: 293 GFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIV 350
G+A +SGIPY GLIKNRY+GRTFI PS R VK+KLS VR VV GKRVV++DDSIV
Sbjct: 300 GYAEQSGIPYELGLIKNRYVGRTFIQPSQALREQGVKMKLSAVRGVVEGKRVVMIDDSIV 359
Query: 351 RGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIG 410
RGTT RIV MLR+AGA+EVHVRI++PPI++PC+ GID T+ ELIAA SIE++RK++G
Sbjct: 360 RGTTSRRIVNMLREAGAKEVHVRISAPPIKHPCFYGIDTSTKEELIAATHSIEEMRKQMG 419
Query: 411 ADSLAYLSIEGLKRAVGTKN------LCMACLTGEYP 441
ADSL++LS+EGL + VG N C+AC TG+YP
Sbjct: 420 ADSLSFLSLEGLVKGVGRSNEVSSCGQCLACFTGQYP 456
>sp|O26742|PUR1_METTH AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|7433952|pir||H69185
amidophosphoribosyltransferase (EC 2.4.2.14) MTH646
precursor [similarity] - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621728|gb|AAB85151.1| (AE000845)
amidophosphoribosyltransferase [Methanobacterium
thermoautotrophicum]
Length = 474
Score = 398 bits (1011), Expect = e-110
Identities = 217/450 (48%), Positives = 290/450 (64%), Gaps = 15/450 (3%)
Query: 7 MREKCGIFGVSSED----AVRKTYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEV 61
+R+KCGI G+ S+D + YY L ALQHRGQE AGIS +NG I T +G GLV +V
Sbjct: 7 VRDKCGIVGIYSQDKKTGVASQIYYALYALQHRGQESAGISTFNGNDILTHRGMGLVCDV 66
Query: 62 FDENSLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRL 118
F+ L L N+ IGHVRYST+G + QP G ++AIAHNG + N + LR
Sbjct: 67 FNPEKLEELKGNVGIGHVRYSTTGESRIENSQPFWSEFQGGKIAIAHNGDIINSMELREE 126
Query: 119 YEGMGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAAR 178
E G F S+ D+EVI Y + + +++RV E++ G+YS+++L + + R
Sbjct: 127 LEEEGHNFVSTTDSEVICHLLSREYDEKPNMIYSIKRVSEQLVGSYSLVVLLNQDLYVVR 186
Query: 179 DPVGFRPLVFG-EGDGYYFASEDSALRMFGLE-TRDVLPGEVFVID-GESYESKVLAREK 235
DPVG +PL F +G ASE A + G E RDV PGE+ ++ G+SY +
Sbjct: 187 DPVGIKPLAFARKGSTQIVASETVAFDVIGAEHVRDVQPGEILHLNRGKSYWVANAPNTR 246
Query: 236 HAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFA 295
A+C+FEY+YFARPDS ++G NVY R +G L RE PA DVV+ VPDS AA+G++
Sbjct: 247 RAHCMFEYVYFARPDSVIDGRNVYRVRLNIGEALYREHPANADVVVPVPDSSIPAAIGYS 306
Query: 296 HESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGT 353
SGIPY EGLIKNRY+GRTFIMP+ R VKLK++P+R + GKR+VL+DDSIVRGT
Sbjct: 307 RASGIPYGEGLIKNRYVGRTFIMPTQEERETAVKLKMNPIRSELEGKRIVLIDDSIVRGT 366
Query: 354 TMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADS 413
T ++ ++RDAGA E+H+RI PPI+ PCY GI + T+ ELIA+ R++E+IR+ IG DS
Sbjct: 367 TSRALIDIIRDAGAEEIHLRIGCPPIKSPCYYGIAMATKKELIASTRNVEEIRRIIGVDS 426
Query: 414 LAYLSIEGLKRAVGTKN--LCMACLTGEYP 441
L YLSIE L +G K LC CL G+YP
Sbjct: 427 LGYLSIESLVECIGIKKGFLCTGCLDGDYP 456
>sp|P00497|PUR1_BACSU AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|66592|pir||XQBS
amidophosphoribosyltransferase (EC 2.4.2.14) purF
precursor [validated] - Bacillus subtilis
>gi|143370|gb|AAA22680.1| (J02732)
phosphoribosylpyrophosphate amidotransferase (PUR-F; EC
2.4.2.14) [Bacillus subtilis]
>gi|2632963|emb|CAB12469.1| (Z99107)
phosphoribosylpyrophosphate amidotransferase [Bacillus
subtilis]
Length = 476
Score = 393 bits (1000), Expect = e-108
Identities = 226/460 (49%), Positives = 303/460 (65%), Gaps = 23/460 (5%)
Query: 1 MAKVRGMREKCGIFGV-SSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLV 58
+A+++G+ E+CG+FG+ E+A + TYYGL +LQHRGQEGAGI +G ++ KG GL+
Sbjct: 2 LAEIKGLNEECGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLI 61
Query: 59 SEVFDENSLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGY-ELAIAHNGTLTNFIP 114
+EVF L+ + AIGHVRY+T+G VQPL R LA+AHNG L N
Sbjct: 62 TEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQ 121
Query: 115 LRRLYEGMGIKFHSSVDTEVIG--ISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDG 172
L++ E G F +S DTEV+ I H++ +KD+ ++ +KGAY+ LI+ +
Sbjct: 122 LKQQLENQGSIFQTSSDTEVLAHLIKRSGHFT-LKDQ---IKNSLSMLKGAYAFLIMTET 177
Query: 173 KIIAARDPVGFRPLVFGE-GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKV 230
++I A DP G RPL G GD Y ASE A + G R+V PGE+ +I+ E +S+
Sbjct: 178 EMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSER 237
Query: 231 LARE-KHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRT 289
+ + C EYIYF+RPDS ++GINV+ AR +G LA+ES E DVV VPDS +
Sbjct: 238 FSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSIS 297
Query: 290 AALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDD 347
AA+G+A +GIPY GLIKNRY+GRTFI PS R V++KLS VR VV GKRVV+VDD
Sbjct: 298 AAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDD 357
Query: 348 SIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRK 407
SIVRGTT RIV MLR+AGA EVHV+I+SPPI +PC+ GID T ELIA+ S+ +IR+
Sbjct: 358 SIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVGEIRQ 417
Query: 408 EIGADSLAYLSIEGLKRAVGTK------NLCMACLTGEYP 441
EIGAD+L++LS+EGL + +G K C+AC TG+YP
Sbjct: 418 EIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYP 457
>pdb|1AO0|A Chain A, Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase From B. Subtilis Complexed With Adp And
Gmp >gi|2624598|pdb|1AO0|B Chain B, Glutamine
Phosphoribosylpyrophosphate (Prpp) Amidotransferase From
B. Subtilis Complexed With Adp And Gmp
>gi|2624599|pdb|1AO0|C Chain C, Glutamine
Phosphoribosylpyrophosphate (Prpp) Amidotransferase From
B. Subtilis Complexed With Adp And Gmp
>gi|2624600|pdb|1AO0|D Chain D, Glutamine
Phosphoribosylpyrophosphate (Prpp) Amidotransferase From
B. Subtilis Complexed With Adp And Gmp
Length = 459
Score = 386 bits (981), Expect = e-106
Identities = 224/450 (49%), Positives = 295/450 (64%), Gaps = 23/450 (5%)
Query: 11 CGIFGV-SSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDENSLN 68
CG+FG+ E+A + TYYGL +LQHRGQEGAGI +G ++ KG GL++EVF L+
Sbjct: 1 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELS 60
Query: 69 -LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGY-ELAIAHNGTLTNFIPLRRLYEGMGI 124
+ AIGHVRY+T+G VQPL R LA+AHNG L N L++ E G
Sbjct: 61 KVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGS 120
Query: 125 KFHSSVDTEVIG--ISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVG 182
F +S DTEV+ I H++ +KD+ ++ +KGAY+ LI+ + ++I A DP G
Sbjct: 121 IFQTSSDTEVLAHLIKRSGHFT-LKDQ---IKNSLSMLKGAYAFLIMTETEMIVALDPNG 176
Query: 183 FRPLVFGE-GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLARE-KHAYC 239
RPL G GD Y ASE A + G R+V PGE+ +I+ E +S+ + + C
Sbjct: 177 LRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSIC 236
Query: 240 VFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESG 299
EYIYF+RPDS ++GINV+ AR +G LA+ES E DVV VPDS +AA+G+A +G
Sbjct: 237 SMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATG 296
Query: 300 IPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTR 357
IPY GLIKNRY+GRTFI PS R V++KLS VR VV GKRVV+VDDSIVRGTT R
Sbjct: 297 IPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRR 356
Query: 358 IVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYL 417
IV MLR+AGA EVHV+I+SPPI +PC+ GID T ELIA+ S+E+IR+EIGAD+L++L
Sbjct: 357 IVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVEEIRQEIGADTLSFL 416
Query: 418 SIEGLKRAVGTK------NLCMACLTGEYP 441
S+EGL + +G K C+AC TG+YP
Sbjct: 417 SVEGLLKGIGRKYDDSNCGQCLACFTGKYP 446
>gb|AAD00109.1| (U64826) glutamine phosphoribosylpyrophosphate amidotransferase
[Streptomyces lividans] >gi|5918488|emb|CAB56366.1|
(AL118514) amidophosphoribosyltransferase [Streptomyces
coelicolor A3(2)]
Length = 530
Score = 386 bits (980), Expect = e-106
Identities = 216/461 (46%), Positives = 295/461 (63%), Gaps = 27/461 (5%)
Query: 5 RGMREKCGIFGV--SSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEV 61
+G ++ CG+FGV E+ + TY+GL ALQHRGQE AGI+V NG +I K GLVS+V
Sbjct: 39 KGPQDACGVFGVWAPGEEVAKLTYFGLYALQHRGQESAGIAVSNGSQILVFKDMGLVSQV 98
Query: 62 FDENSL-NLASNIAIGHVRYSTSGSL--SEVQPLEVRCCGYELAIAHNGTLTNFIPLRRL 118
FDE SL +L +IA+GH RYST+G+ QP +A+ HNG L N L L
Sbjct: 99 FDETSLGSLQGHIAVGHARYSTTGASVWENAQPTFRATAQGSIALGHNGNLVNTAQLAGL 158
Query: 119 Y------EGMGIKFHSSVDTEVIGISFLNHYSQVKDEF------EAMRRVFEEVKGAYSI 166
+G + ++ DT++I QV D+ EA +V +V+GA+S+
Sbjct: 159 VADLPKQDGRSTRVAATNDTDLITALLAG---QVDDDGKPLTVEEAAGKVLPQVRGAFSL 215
Query: 167 LILFDGKIIAARDPVGFRPLVFGEGD-GYYFASEDSALRMFGLE-TRDVLPGEVFVIDGE 224
+ + + + AARDP G RPLV G + G+ ASE +AL + G R++ PGE ID
Sbjct: 216 VFMDEHTLYAARDPQGIRPLVLGRLERGWVVASESAALDICGASYVREIEPGEFVAIDEN 275
Query: 225 SYESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVP 284
+ A K CVFEY+Y ARPD+ + G NVY +R MG +LA+E+PAE D+VIA P
Sbjct: 276 GLRTSRFAEAKPKGCVFEYVYLARPDTDIAGRNVYLSRVEMGRKLAKEAPAEADLVIATP 335
Query: 285 DSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRV 342
+SG AA+G+A SGIP+ GL+KN Y+GRTFI PS R L ++LKL+P++EV+ GKR+
Sbjct: 336 ESGTPAAIGYAEASGIPFGNGLVKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIKGKRL 395
Query: 343 VLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSI 402
V+VDDSIVRG T +V+MLR+AGA E+H+RI+SPP+++PC+ GID TR ELIA S+
Sbjct: 396 VVVDDSIVRGNTQRALVRMLREAGAAEIHIRISSPPVKWPCFFGIDFATRAELIANGMSV 455
Query: 403 EDIRKEIGADSLAYLSIEGLKRA--VGTKNLCMACLTGEYP 441
E+I +GADSLAY+SI+G+ A + NLC AC GEYP
Sbjct: 456 EEIGTSMGADSLAYISIDGMIEATTIAKPNLCRACFDGEYP 496
>pdb|1GPH|1 Chain 1, Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase (E.C.2.4.2.14) >gi|576139|pdb|1GPH|2
Chain 2, Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase (E.C.2.4.2.14) >gi|576140|pdb|1GPH|3
Chain 3, Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase (E.C.2.4.2.14) >gi|576141|pdb|1GPH|4
Chain 4, Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase (E.C.2.4.2.14)
Length = 465
Score = 385 bits (978), Expect = e-106
Identities = 223/450 (49%), Positives = 295/450 (65%), Gaps = 23/450 (5%)
Query: 11 CGIFGV-SSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDENSLN 68
CG+FG+ E+A + TYYGL +LQHRGQEGAGI +G ++ KG GL++EVF L+
Sbjct: 1 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELS 60
Query: 69 -LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGY-ELAIAHNGTLTNFIPLRRLYEGMGI 124
+ AIGHVRY+T+G VQPL R LA+AHNG L N L++ E G
Sbjct: 61 KVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGS 120
Query: 125 KFHSSVDTEVIG--ISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVG 182
F +S DTEV+ I H++ +KD+ ++ +KGAY+ LI+ + ++I A DP G
Sbjct: 121 IFQTSSDTEVLAHLIKRSGHFT-LKDQ---IKNSLSMLKGAYAFLIMTETEMIVALDPNG 176
Query: 183 FRPLVFGE-GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLARE-KHAYC 239
RPL G GD Y ASE A + G R+V PGE+ +I+ E +S+ + + C
Sbjct: 177 LRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSIC 236
Query: 240 VFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESG 299
EYIYF+RPDS ++GINV+ AR +G LA+ES E DVV VPDS +AA+G+A +G
Sbjct: 237 SMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATG 296
Query: 300 IPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTR 357
IPY GLIKNRY+GRTFI PS R V++KLS VR VV GKRVV+VDDSIVRGTT R
Sbjct: 297 IPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRR 356
Query: 358 IVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYL 417
IV MLR+AGA EVHV+I+SPPI +PC+ GID T ELIA+ S+++IR+EIGAD+L++L
Sbjct: 357 IVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFL 416
Query: 418 SIEGLKRAVGTK------NLCMACLTGEYP 441
S+EGL + +G K C+AC TG+YP
Sbjct: 417 SVEGLLKGIGRKYDDSNCGQCLACFTGKYP 446
>gb|AAD26498.1|AC007195_12 (AC007195) amidophosphoribosyltransferase [Arabidopsis thaliana]
Length = 566
Score = 382 bits (971), Expect = e-105
Identities = 221/448 (49%), Positives = 300/448 (66%), Gaps = 16/448 (3%)
Query: 8 REKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGISVWNGR--IRTIKGHGLVSEVFDE 64
RE+CG+ G+ + +A R Y L ALQHRGQEGAGI + ++TI G GLVSEVF+E
Sbjct: 88 REECGVVGIYGDPEASRLCYLALHALQHRGQEGAGIVTVSPEKVLQTITGVGLVSEVFNE 147
Query: 65 NSLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
+ L+ L AIGHVRYST+G+ L VQP + +AHNG L N+ LR + E
Sbjct: 148 SKLDQLPGEFAIGHVRYSTAGASMLKNVQPFVAGYRFGSIGVAHNGNLVNYKTLRAMLEE 207
Query: 122 MGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPV 181
G F++S DTEV+ L S+ + F + E+++GAYS++ + + K++A RDP
Sbjct: 208 NGSIFNTSSDTEVV--LHLIAISKARPFFMRIIDACEKLQGAYSMVFVTEDKLVAVRDPY 265
Query: 182 GFRPLVFGE--GDGYYFASEDSALRMF-GLETRDVLPGEVFVIDGESYESKVLARE-KHA 237
GFRPLV G FASE AL + R+V PGEV V+D + +S+ L + +
Sbjct: 266 GFRPLVMGRRSNGAVVFASETCALDLIEATYEREVYPGEVLVVDKDGVKSQCLMPKFEPK 325
Query: 238 YCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHE 297
C+FE+IYF+ P+S + G +VY +R+ G LA ESP E DVVIAVPDSG AALG+A +
Sbjct: 326 QCIFEHIYFSLPNSIVFGRSVYESRHVFGEILATESPVECDVVIAVPDSGVVAALGYAAK 385
Query: 298 SGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTM 355
SG+P+ +GLI++ Y+GRTFI PS R VKLKLSPVR V+ GKRVV+VDDSIVRGTT
Sbjct: 386 SGVPFQQGLIRSHYVGRTFIEPSQKIRDFGVKLKLSPVRGVLEGKRVVVVDDSIVRGTTS 445
Query: 356 TRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLA 415
++IV++LR+AGA+EVH+RIASPPI CY G+D P+ ELI+ S+E+I + IG+DSLA
Sbjct: 446 SKIVRLLREAGAKEVHMRIASPPIVASCYYGVDTPSSEELISNRLSVEEINEFIGSDSLA 505
Query: 416 YLSIEGLKRAVG--TKNLCMACLTGEYP 441
+LS + LK+ +G +K+ C AC TG+YP
Sbjct: 506 FLSFDTLKKHLGKDSKSFCYACFTGDYP 533
>pir||S52622 amidophosphoribosyltransferase (EC 2.4.2.14) 1 precursor -
Arabidopsis thaliana >gi|469193|dbj|BAA06023.1| (D28868)
amidophosphoribosyltransferase [Arabidopsis thaliana]
Length = 511
Score = 379 bits (964), Expect = e-104
Identities = 220/448 (49%), Positives = 299/448 (66%), Gaps = 16/448 (3%)
Query: 8 REKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGISVWNGR--IRTIKGHGLVSEVFDE 64
RE+CG+ G+ + +A R Y L ALQHRGQEGAGI + ++TI G GLVSEVF+E
Sbjct: 33 REECGVVGIYGDPEASRLFYLALHALQHRGQEGAGIVTVSPEKVLQTITGVGLVSEVFNE 92
Query: 65 NSLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
+ L+ L AI HVRYST+G+ L VQP + +AHNG L N+ LR + E
Sbjct: 93 SKLDQLPGEFAIAHVRYSTAGASMLKNVQPFVAGYRFGSIGVAHNGNLVNYKTLRAMLEE 152
Query: 122 MGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPV 181
G F++S DTEV+ L S+ + F + E+++GAYS++ + + K++A RDP
Sbjct: 153 NGSIFNTSSDTEVV--LHLIAISKARPFFMRIIDACEKLQGAYSMVFVTEDKLVAVRDPY 210
Query: 182 GFRPLVFGE--GDGYYFASEDSALRMF-GLETRDVLPGEVFVIDGESYESKVLARE-KHA 237
GFRPLV G FASE AL + R+V PGEV V+D + +S+ L + +
Sbjct: 211 GFRPLVMGRRSNGAVVFASETCALDLIEATYEREVYPGEVLVVDKDGVKSQCLMPKFEPK 270
Query: 238 YCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHE 297
C+FE+IYF+ P+S + G +VY +R+ G LA ESP E DVVIAVPDSG AALG+A +
Sbjct: 271 QCIFEHIYFSLPNSIVFGRSVYESRHVFGEILATESPVECDVVIAVPDSGVVAALGYAAK 330
Query: 298 SGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTM 355
SG+P+ +GLI++ Y+GRTFI PS R VKLKLSPVR V+ GKRVV+VDDSIVRGTT
Sbjct: 331 SGVPFQQGLIRSHYVGRTFIEPSQKIRDFGVKLKLSPVRGVLEGKRVVVVDDSIVRGTTS 390
Query: 356 TRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLA 415
++IV++LR+AGA+EVH+RIASPPI CY G+D P+ ELI+ S+E+I + IG+DSLA
Sbjct: 391 SKIVRLLREAGAKEVHMRIASPPIVASCYYGVDTPSSEELISNRLSVEEINEFIGSDSLA 450
Query: 416 YLSIEGLKRAVG--TKNLCMACLTGEYP 441
+LS + LK+ +G +K+ C AC TG+YP
Sbjct: 451 FLSFDTLKKHLGKDSKSFCYACFTGDYP 478
>pir||A72277 amidophosphoribosyltransferase (EC 2.4.2.14) TM1247 [similarity] -
Thermotoga maritima (strain MSB8)
>gi|4981802|gb|AAD36322.1|AE001780_6 (AE001780)
amidophosphoribosyltransferase [Thermotoga maritima]
Length = 431
Score = 379 bits (963), Expect = e-104
Identities = 212/434 (48%), Positives = 288/434 (65%), Gaps = 11/434 (2%)
Query: 11 CGIFGV-SSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSEVFDENSLNL 69
CGI GV + +DA + L+ LQHRGQE G+ V +TIKG GLV V E+
Sbjct: 2 CGIAGVWNVKDAFSVLHDVLLGLQHRGQESVGVVV--DGFKTIKGKGLVDTVLTEDRWED 59
Query: 70 ASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFHSS 129
A IGHVRYST+GSL ++QP+ LAIAHNG + N + + G F SS
Sbjct: 60 AEK-GIGHVRYSTAGSLEDIQPIVAFTRKGRLAIAHNGNIPNGEKWIEMLKEKGAVFQSS 118
Query: 130 VDTEVIGISFLNHYSQVKDEF-EAMRRVFEEVKGAYSILILFDGKIIAARDPVGFRPLVF 188
+D+EV FL+ S + + E++ + ++V AYS+LIL + + AARDP G RPL +
Sbjct: 119 LDSEV----FLHLISMSEGDLKESIVKALKKVPLAYSLLILHEEFLAAARDPYGVRPLFY 174
Query: 189 GE-GDGYYFASEDSALRMFGLETRDVLP-GEVFVIDGESYESKVLAREKHAYCVFEYIYF 246
G+ GDG ASED+AL+ G+E + +P G V + E+ ++++ +C FE+IYF
Sbjct: 175 GKYGDGIVVASEDAALKAIGVEDIEEVPSGTVVFFSNKGTETVRFSKKEKRFCSFEFIYF 234
Query: 247 ARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGL 306
ARPDS +V+ ARYRMG EL RE+P E DVV+ V DSG + A+GF+ SGIP GL
Sbjct: 235 ARPDSHFLDQSVHIARYRMGEELYRENPIEADVVVPVLDSGLSGAMGFSSASGIPLDIGL 294
Query: 307 IKNRYIGRTFIMPSGRGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAG 366
++NRY+GR+FIMP R VK KL P+ +VV+GKRVV++DDSIVRGTTM IVK+LR+AG
Sbjct: 295 MRNRYVGRSFIMPVDREKIVKKKLVPIEDVVSGKRVVVIDDSIVRGTTMGIIVKILREAG 354
Query: 367 AREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRAV 426
A+EVHV I SPP+R+PC+ GID + EL+A R++E+++K + ADSL YLS+EGLKRA+
Sbjct: 355 AKEVHVGIHSPPVRFPCFYGIDTARKKELVAGERAVEEVKKIVNADSLFYLSLEGLKRAI 414
Query: 427 GTKNLCMACLTGEY 440
G LC+AC +GEY
Sbjct: 415 GRSELCVACFSGEY 428
>emb|CAC12366.1| (AL445067) probable amidophosphoribosyltransferase [Thermoplasma
acidophilum]
Length = 474
Score = 378 bits (960), Expect = e-104
Identities = 209/446 (46%), Positives = 289/446 (63%), Gaps = 16/446 (3%)
Query: 9 EKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIK-GHGLVSEVFDENS 66
E C + G +A L LQHRGQE AG++V++GR +K G GLV++VF+ +
Sbjct: 18 EDCAVVGFKGRINAYEPIITALRTLQHRGQESAGMAVFDGRKTVLKKGRGLVTDVFNPAT 77
Query: 67 LNLASNIAIGHVRYSTSGSLSEVQ--PLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
++ + +GH RYST+GS + P + ++++HNG + N L+ + G+
Sbjct: 78 DSIKGKVGVGHTRYSTAGSKDVIDAGPFVINSQVGFISLSHNGEIVNADELKEEMKKEGV 137
Query: 125 KFHSSVDTEVIGISFLNHYSQ--VKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVG 182
F S DTEV+ + S+ +K FE ++GAY+ + + ++ A RDP G
Sbjct: 138 NFQSDSDTEVLLAELSRNISKYGLKKGFEVSMNT---LRGAYACAVGINDRLFAMRDPNG 194
Query: 183 FRPLVFGEG-DGYYFASEDSAL-RMFGLETRDVLPGEVFVIDGESYESKVLAR-EKHAYC 239
RPL+ G+ DGY ASE A+ + G R+V PGEV + + ++ L EK A+C
Sbjct: 195 IRPLIVGKNADGYIIASESCAIDALDGTIIRNVEPGEVVELTDDGLKTIALHEGEKTAHC 254
Query: 240 VFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESG 299
+FEY+YF+RPDST++GINVY AR +MG+ LA+ESP E D+VI VPDSGR+ A+GF+ +SG
Sbjct: 255 MFEYVYFSRPDSTIDGINVYMARVKMGMMLAKESPVEADMVIPVPDSGRSQAIGFSMQSG 314
Query: 300 IPYMEGLIKNRYIGRTFIMP--SGRGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTR 357
IPY EGL+KNRY RTFIMP S R ++LKL+PVREV++GKR+VLVDDSIVRG TM
Sbjct: 315 IPYTEGLMKNRYSERTFIMPTQSDRKAAIRLKLNPVREVISGKRIVLVDDSIVRGNTMRF 374
Query: 358 IVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYL 417
IV M+R GA+EVHVRI SP I PCY G+D+ T+ + IA ++ +I EIGADSLA+L
Sbjct: 375 IVSMMRKYGAKEVHVRIGSPHIIAPCYFGVDMKTKDQFIARGKTDAEINSEIGADSLAFL 434
Query: 418 SIEGLKRAVG--TKNLCMACLTGEYP 441
SI+GLK A+G NLC+ CLTG YP
Sbjct: 435 SIDGLKEAIGLDENNLCLGCLTGTYP 460
>pir||A75545 amidophosphoribosyltransferase (EC 2.4.2.14) DR0220 precursor
[similarity] - Deinococcus radiodurans (strain R1)
>gi|6457891|gb|AAF09806.1|AE001884_1 (AE001884)
amidophosphoribosyltransferase [Deinococcus radiodurans]
Length = 477
Score = 377 bits (958), Expect = e-103
Identities = 216/449 (48%), Positives = 287/449 (63%), Gaps = 18/449 (4%)
Query: 8 REKCGIFGVSS---EDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFD 63
RE+CG+FG+ S D TY GL ALQHRGQE AG+ V +G R K GLV++VFD
Sbjct: 16 REECGVFGIYSAQPNDLAWLTYLGLFALQHRGQEAAGMCVSDGDRFHVEKDLGLVTQVFD 75
Query: 64 ENSLN----LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRR 117
E L+ + ++IGHVRYST+GS QPL R L +AHNG N + +RR
Sbjct: 76 ERRLDSVRLAGAQVSIGHVRYSTTGSNLRFNAQPLTTRTNKGILGMAHNGNFVNALEVRR 135
Query: 118 LYEGMGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAA 177
G F ++ D+EV+ ++ + S++ D EA + ++G Y+ +++ +++
Sbjct: 136 EMLEEGALFATTNDSEVM-LNLIARESRM-DLVEATAAAMQRLRGGYACVLMSRSQLLGF 193
Query: 178 RDPVGFRPLVFG--EGDGYYFASEDSALRMFGLET-RDVLPGEVFVIDGESYESKVLARE 234
RDP G RPLV G E + ASE AL G RDV PGE+ ID E S ++
Sbjct: 194 RDPHGVRPLVIGQREDGAWVLASEPCALYAIGARLIRDVAPGELVWIDREGLHSLMVEAR 253
Query: 235 KHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGF 294
+ C FE+IYFAR DS L+GI+ + +R RMG +LARE P E D+V+ VPDSG AA+G+
Sbjct: 254 QPTPCSFEWIYFARSDSQLDGIDTHESRIRMGQQLAREKPVEADIVVPVPDSGIGAAIGY 313
Query: 295 AHESGIPYMEGLIKNRYIGRTFIMPS--GRGLKVKLKLSPVREVVNGKRVVLVDDSIVRG 352
A ESGIP+ GL KN Y GRTFI P+ R LKVK+KLSP V GKRVVLVDDSIVRG
Sbjct: 314 ARESGIPFDYGLYKNPYAGRTFIAPTQEARELKVKMKLSPT-SAVRGKRVVLVDDSIVRG 372
Query: 353 TTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGAD 412
TT +IV +LRDAGA EVH R++SPPI +PC+ GID R EL+A+ S+++IR IGAD
Sbjct: 373 TTSRQIVNLLRDAGATEVHFRVSSPPITHPCFYGIDTAARKELVASTHSVDEIRDLIGAD 432
Query: 413 SLAYLSIEGLKRAVGTKNLCMACLTGEYP 441
+LA++S +GL++A+G LC AC TG+YP
Sbjct: 433 TLAFISEQGLRKAIGGPGLCSACFTGDYP 461
>pir||S52621 amidophosphoribosyltransferase - Arabidopsis thaliana
>gi|469195|dbj|BAA06024.1| (D28869)
amidophosphoribosyltransferase [Arabidopsis thaliana]
Length = 548
Score = 375 bits (953), Expect = e-103
Identities = 220/448 (49%), Positives = 299/448 (66%), Gaps = 16/448 (3%)
Query: 8 REKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGI-SVWNGRI-RTIKGHGLVSEVFDE 64
RE+CG+ G+ + +A R Y L ALQHRGQEGAGI +V ++ +TI G GLVSEVF E
Sbjct: 71 REECGVVGIYGDSEASRLCYLALHALQHRGQEGAGIVTVSKDKVLQTITGVGLVSEVFSE 130
Query: 65 NSLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
+ L+ L +IAIGHVRYST+GS L VQP + +AHNG L N+ LR E
Sbjct: 131 SKLDQLPGDIAIGHVRYSTAGSSMLKNVQPFVAGYRFGSVGVAHNGNLVNYTKLRADLEE 190
Query: 122 MGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPV 181
G F++S DTEV+ L S+ + F + E+++GAYS++ + + K++A RDP
Sbjct: 191 NGSIFNTSSDTEVV--LHLIAISKARPFFMRIVDACEKLQGAYSMVFVTEDKLVAVRDPH 248
Query: 182 GFRPLVFGE--GDGYYFASEDSALRMF-GLETRDVLPGEVFVIDGESYESKVLA-REKHA 237
GFRPLV G FASE AL + R+V PGEV V+D + + + L +
Sbjct: 249 GFRPLVMGRRSNGAVVFASETCALDLIEATYEREVYPGEVLVVDKDGVKCQCLMPHPEPK 308
Query: 238 YCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHE 297
C+FE+IYF+ P+S + G +VY +R+ G LA ESP + DVVIAVPDSG AALG+A +
Sbjct: 309 QCIFEHIYFSLPNSIVFGRSVYESRHVFGEILATESPVDCDVVIAVPDSGVVAALGYAAK 368
Query: 298 SGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTM 355
+G+ + +GLI++ Y+GRTFI PS R VKLKLSPVR V+ GKRVV+VDDSIVRGTT
Sbjct: 369 AGVAFQQGLIRSHYVGRTFIEPSQKIRDFGVKLKLSPVRGVLEGKRVVVVDDSIVRGTTS 428
Query: 356 TRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLA 415
++IV++LR+AGA+EVH+RIASPPI CY G+D P+ +ELI+ S+++IR IG DSLA
Sbjct: 429 SKIVRLLREAGAKEVHMRIASPPIIASCYYGVDTPSSNELISNRMSVDEIRDYIGCDSLA 488
Query: 416 YLSIEGLKRAVG--TKNLCMACLTGEYP 441
+LS E LK+ +G +++ C AC TG+YP
Sbjct: 489 FLSFETLKKHLGEDSRSFCYACFTGDYP 516
>pir||T05294 amidophosphoribosyltransferase (EC 2.4.2.14) 2 precursor -
Arabidopsis thaliana >gi|3096943|emb|CAA18853.1|
(AL023094) amidophosphoribosyltransferase 2 precursor
[Arabidopsis thaliana] >gi|7270425|emb|CAB80191.1|
(AL161586) amidophosphoribosyltransferase 2 precursor
[Arabidopsis thaliana]
Length = 561
Score = 375 bits (953), Expect = e-103
Identities = 220/448 (49%), Positives = 299/448 (66%), Gaps = 16/448 (3%)
Query: 8 REKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGI-SVWNGRI-RTIKGHGLVSEVFDE 64
RE+CG+ G+ + +A R Y L ALQHRGQEGAGI +V ++ +TI G GLVSEVF E
Sbjct: 84 REECGVVGIYGDSEASRLCYLALHALQHRGQEGAGIVTVSKDKVLQTITGVGLVSEVFSE 143
Query: 65 NSLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
+ L+ L +IAIGHVRYST+GS L VQP + +AHNG L N+ LR E
Sbjct: 144 SKLDQLPGDIAIGHVRYSTAGSSMLKNVQPFVAGYRFGSVGVAHNGNLVNYTKLRADLEE 203
Query: 122 MGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPV 181
G F++S DTEV+ L S+ + F + E+++GAYS++ + + K++A RDP
Sbjct: 204 NGSIFNTSSDTEVV--LHLIAISKARPFFMRIVDACEKLQGAYSMVFVTEDKLVAVRDPH 261
Query: 182 GFRPLVFGE--GDGYYFASEDSALRMF-GLETRDVLPGEVFVIDGESYESKVLA-REKHA 237
GFRPLV G FASE AL + R+V PGEV V+D + + + L +
Sbjct: 262 GFRPLVMGRRSNGAVVFASETCALDLIEATYEREVYPGEVLVVDKDGVKCQCLMPHPEPK 321
Query: 238 YCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHE 297
C+FE+IYF+ P+S + G +VY +R+ G LA ESP + DVVIAVPDSG AALG+A +
Sbjct: 322 QCIFEHIYFSLPNSIVFGRSVYESRHVFGEILATESPVDCDVVIAVPDSGVVAALGYAAK 381
Query: 298 SGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTM 355
+G+ + +GLI++ Y+GRTFI PS R VKLKLSPVR V+ GKRVV+VDDSIVRGTT
Sbjct: 382 AGVAFQQGLIRSHYVGRTFIEPSQKIRDFGVKLKLSPVRGVLEGKRVVVVDDSIVRGTTS 441
Query: 356 TRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLA 415
++IV++LR+AGA+EVH+RIASPPI CY G+D P+ +ELI+ S+++IR IG DSLA
Sbjct: 442 SKIVRLLREAGAKEVHMRIASPPIIASCYYGVDTPSSNELISNRMSVDEIRDYIGCDSLA 501
Query: 416 YLSIEGLKRAVG--TKNLCMACLTGEYP 441
+LS E LK+ +G +++ C AC TG+YP
Sbjct: 502 FLSFETLKKHLGEDSRSFCYACFTGDYP 529
>pir||T51702 amidophosphoribosyltransferase (EC 2.4.2.14) [imported] -
Lactococcus lactis >gi|4097534|gb|AAD12627.1| (U64311)
phosphoribosylpyrophosphate amidotransferase
[Lactococcus lactis]
Length = 506
Score = 373 bits (947), Expect = e-102
Identities = 220/460 (47%), Positives = 290/460 (62%), Gaps = 20/460 (4%)
Query: 3 KVRGMREKCGIFGV-SSEDAVRKTYYGLIALQHRGQEGAGISVWN-GRIRTIKGHGLVSE 60
+ + + E+CG+FGV DA R TY+GL ALQHRGQEGAGI V N G++ +G GLV+E
Sbjct: 38 EAKTLNEECGLFGVWGHPDAARLTYFGLHALQHRGQEGAGILVNNNGKLNRHRGLGLVTE 97
Query: 61 VF--DENSLNLASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLR 116
VF +++ L + AIGHVRY+T+GS ++ +QP + L +AHNG LTN LR
Sbjct: 98 VFRHEKDLEELTGSSAIGHVRYATAGSANINNIQPFQFEFHDGSLGLAHNGNLTNAQSLR 157
Query: 117 RLYEGMGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEE---VKGAYSILILFDGK 173
E G F S+ DTE+ L H + E M RV E VKG ++ LI+ +
Sbjct: 158 CELEKSGAIFSSNSDTEI-----LMHLIRRSHHPEFMGRVKEALNTVKGGFAYLIMTENS 212
Query: 174 IIAARDPVGFRPLVFGE--GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGES-YESK 229
I+AA DP GFRPL G+ ASE A + G +DV PGE+ I+ + + +
Sbjct: 213 IVAALDPNGFRPLSIGKMSNGALVVASETCAFDVVGATWIQDVQPGEIIEINDDGIHVDQ 272
Query: 230 VLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRT 289
C EYIYFARPDS + G+NV+ AR R G LA+E+ + D+VI VP+S +
Sbjct: 273 FTDSTNMTICSMEYIYFARPDSNIAGVNVHTARKRSGKILAQEAKIDADIVIGVPNSSLS 332
Query: 290 AALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDD 347
AA G+A ESG+PY GLIKN+Y+ RTFI P+ R V++KLS VR VV GKRV++VDD
Sbjct: 333 AASGYAEESGLPYEMGLIKNQYVARTFIQPTQELREQGVRMKLSAVRGVVEGKRVIMVDD 392
Query: 348 SIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRK 407
SIVRGTT RIVK+L+DAGA EVHV IASP ++YPC+ GIDI R ELIAA + ++IR+
Sbjct: 393 SIVRGTTSRRIVKLLKDAGAAEVHVAIASPALKYPCFYGIDIQDRDELIAATHTTDEIRE 452
Query: 408 EIGADSLAYLSIEGLKRAVGTKNLCMACLTGEYPEWAFNF 447
IGADSL YLS GL A+G LC++ GEYP +++
Sbjct: 453 AIGADSLTYLSQSGLVEAIGHDKLCLSYFDGEYPTPLYDY 492
>sp|O06626|PUR1_MYCTU AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|7433957|pir||A70537
amidophosphoribosyltransferase (EC 2.4.2.14) purF
precursor [similarity] - Mycobacterium tuberculosis
(strain H37RV) >gi|2117274|emb|CAB09103.1| (Z95618) purF
[Mycobacterium tuberculosis]
Length = 527
Score = 364 bits (925), Expect = e-99
Identities = 208/457 (45%), Positives = 285/457 (61%), Gaps = 24/457 (5%)
Query: 8 REKCGIFGV--SSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDE 64
RE+CG+FGV ED + TYYGL ALQHRGQE AGI+V +G ++ K GLVS+VFDE
Sbjct: 32 REECGVFGVWAPGEDVAKLTYYGLYALQHRGQEAAGIAVADGSQVLVFKDLGLVSQVFDE 91
Query: 65 NSLN-LASNIAIGHVRYSTSGSLS--EVQPL-EVRCCGYELAIAHNGTLTNFIPLRRLYE 120
+L + ++AIGH RYST+G + QP+ G +A+ HNG L N L
Sbjct: 92 QTLAAMQGHVAIGHCRYSTTGDTTWENAQPVFRNTAAGTGVALGHNGNLVNAAALAARAR 151
Query: 121 GMGI-----KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKII 175
G+ ++ D++++G + L H + +A + V+GA+ + + + +
Sbjct: 152 DAGLIATRCPAPATTDSDILG-ALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDENTLY 210
Query: 176 AARDPVGFRPLVFGEGD-GYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAR 233
A RDP G RPL G D G+ ASE +AL + G RD+ PGE+ ID + S A
Sbjct: 211 ACRDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLAIDADGVRSTRFAN 270
Query: 234 EKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALG 293
CVFEY+Y ARPDST+ G +V+ AR +G LARE P E D+VI VP+SG AA+G
Sbjct: 271 PTPKGCVFEYVYLARPDSTIAGRSVHAARVEIGRRLARECPVEADLVIGVPESGTPAAVG 330
Query: 294 FAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVR 351
+A ESG+PY +GL+KN Y+GRTFI PS R L ++LKL+P++EV+ GKR+++VDDSIVR
Sbjct: 331 YAQESGVPYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVR 390
Query: 352 GTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIED-----IR 406
G T +V+MLR+AGA E+HVRIASPP+++PC+ GID P+ ELIA ED +R
Sbjct: 391 GNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVENEDEMLEAVR 450
Query: 407 KEIGADSLAYLSIEGLKRA--VGTKNLCMACLTGEYP 441
IGAD+L Y+S+ G+ A T LC AC G+YP
Sbjct: 451 HAIGADTLGYISLRGMVAASEQPTSRLCTACFDGKYP 487
>gb|AAC24007.1| (AF071862) phosphoribosylpyrophosphate amidotransferase [Vigna
unguiculata]
Length = 567
Score = 364 bits (924), Expect = 1e-99
Identities = 214/449 (47%), Positives = 292/449 (64%), Gaps = 19/449 (4%)
Query: 8 REKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGI-SVWNGRIRTIKGHGLVSEVFDEN 65
RE+CG+ G+ + +A R L ALQHRGQEGAGI +V N + T+ G GLVS+VFDE
Sbjct: 76 REECGVVGIYGDPEASRLCSLALHALQHRGQEGAGIVAVDNNVLHTVNGVGLVSDVFDET 135
Query: 66 SLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGM 122
L+ L + AIGHVRYST+G L VQP +A++HNG N+ LR E
Sbjct: 136 KLSQLPGSCAIGHVRYSTAGHSRLCNVQPFVAGYRFGSVAVSHNGNFVNYRSLRAKLEDN 195
Query: 123 GIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRV--FEEVKGAYSILILFDGKIIAARDP 180
G F+++ DT+V+ L+ + K +R V E +KGAYS++ L + K++A +DP
Sbjct: 196 GSIFNTTSDTDVV----LHLIATSKHRPFLLRIVDACENLKGAYSLVFLTEDKLVAVKDP 251
Query: 181 VGFRPLVFGE--GDGYYFASEDSALRMF-GLETRDVLPGEVFVIDGESYESKVLAREKHA 237
GFRPLV G FASE AL + R+V PGEV V+D +S L
Sbjct: 252 FGFRPLVMGRRSNGAVVFASETCALDLIEATYEREVNPGEVVVVDHTGIQSLCLVTHPEP 311
Query: 238 -YCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAH 296
C+FE+IYFA P+S + G +VY +R + G LA ESP E DVVIAVPDSG AALG+A
Sbjct: 312 KQCIFEHIYFALPNSVVFGRSVYESRRKFGEILATESPVECDVVIAVPDSGVVAALGYAA 371
Query: 297 ESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTT 354
++G+P+ +GLI++ Y+GRTFI PS R VKLKL PVR V+ GKRVV+VD+SIVRGTT
Sbjct: 372 KAGVPFQQGLIRSHYVGRTFIEPSQKIRDFGVKLKLFPVRGVLEGKRVVVVDESIVRGTT 431
Query: 355 MTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSL 414
+++IV+++++AGA+EVH+RIA PPI CY G+D P++ ELI+ S+E+IR+ IG+DSL
Sbjct: 432 LSKIVRLIKEAGAKEVHMRIACPPIVGSCYYGVDTPSKEELISNRMSVEEIREFIGSDSL 491
Query: 415 AYLSIEGLKRAV--GTKNLCMACLTGEYP 441
A+L ++ LKR + N C AC +G+YP
Sbjct: 492 AFLPLDTLKRLLEDDAPNYCYACFSGKYP 520
>pir||T06087 amidophosphoribosyltransferase (EC 2.4.2.14) T9A14.160 precursor
[similarity] - Arabidopsis thaliana
>gi|4490340|emb|CAB38622.1| (AL035656)
amidophosphoribosyltransferase-like protein [Arabidopsis
thaliana] >gi|7270871|emb|CAB80551.1| (AL161594)
amidophosphoribosyltransferase-like protein [Arabidopsis
thaliana]
Length = 532
Score = 363 bits (921), Expect = 3e-99
Identities = 213/450 (47%), Positives = 286/450 (63%), Gaps = 17/450 (3%)
Query: 7 MREKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEVFDE 64
+ E+CG+ G+ + +A R +Y L ALQHRGQEGAGI N + +I G GLVS+VF E
Sbjct: 73 LHEECGVVGIHGDPEASRLSYLALHALQHRGQEGAGIVAANQNGLESITGVGLVSDVFTE 132
Query: 65 NSLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
+ LN L +IAIGHVRYSTSG+ L VQP C LA+AHNG N+ L+ E
Sbjct: 133 SKLNNLPGDIAIGHVRYSTSGASMLKNVQPFIASCKLGSLAVAHNGNFVNYKQLKTKLEE 192
Query: 122 MGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPV 181
MG F +S DTE++ L S+ K + E+++GAYS++ +F+ K+IA RDP
Sbjct: 193 MGSIFITSSDTELV--LHLIAKSKAKTFLLRVIDACEKLRGAYSMVFVFEDKLIAVRDPF 250
Query: 182 GFRPLVFGE--GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKV--LAREKH 236
GFRPLV G FASE AL + R+V PGE+ V+D +S + ++ +
Sbjct: 251 GFRPLVMGRRSNGAVVFASETCALDLIDATYEREVCPGEIVVVDRNHGDSSMFMISHPEQ 310
Query: 237 AYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAH 296
CVFE+ YF++P+S + G +VY R G LA +P + DVVIAVPDSG AALG+A
Sbjct: 311 KQCVFEHGYFSQPNSIVFGRSVYETRRMYGEILATVAPVDCDVVIAVPDSGTVAALGYAA 370
Query: 297 ESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTT 354
++G+P+ GL+++ Y RTFI P+ R VK+KLSPVR V+ GKRVV+VDDSIVRGTT
Sbjct: 371 KAGVPFQIGLLRSHYAKRTFIEPTQEIRDFAVKVKLSPVRAVLEGKRVVVVDDSIVRGTT 430
Query: 355 MTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSL 414
+IV+MLRDAGA+EVH+RIA PP+ CY G+D P ELI++ S+E I+K I DSL
Sbjct: 431 SLKIVRMLRDAGAKEVHMRIALPPMIASCYYGVDTPRSQELISSKMSVEAIQKHINCDSL 490
Query: 415 AYLSIEGLKRAVG---TKNLCMACLTGEYP 441
A+L ++ LK G + C AC TG+YP
Sbjct: 491 AFLPLDSLKGVYGPVESHRYCYACFTGKYP 520
>emb|CAB96578.1| (AJ278609) phosphoribosyl pyrophosphate amidotransferease
[Mycobacterium smegmatis]
Length = 511
Score = 362 bits (920), Expect = 4e-99
Identities = 211/459 (45%), Positives = 286/459 (61%), Gaps = 26/459 (5%)
Query: 8 REKCGIFGV--SSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDE 64
RE+CG+FGV E+ + TYYGL ALQHRGQE AGI+V +G ++ K GLVS+VFDE
Sbjct: 14 REECGVFGVWAPGEEVAKLTYYGLYALQHRGQEAAGIAVADGSQVLVFKDLGLVSQVFDE 73
Query: 65 NSLN-LASNIAIGHVRYSTSGSLS--EVQPL-EVRCCGYELAIAHNGTLTNFIPLRRLYE 120
+L + ++A+GH RYST+GS + QP+ G +A+ HNG L N L
Sbjct: 74 QTLAAMPGHVAVGHCRYSTTGSTTWENAQPVFRNTAAGTGVALGHNGNLVNTAELAARAR 133
Query: 121 GMGIKF-----HSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKII 175
G+ ++ D++++G + L H + +A + V+GA+ + + + +
Sbjct: 134 DNGLIELKGGPAATTDSDILG-ALLAHGAADATLEQAALELLPTVRGAFCLTFMDENTLY 192
Query: 176 AARDPVGFRPLVFGEGD-GYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAR 233
AARDP G RPL G D G+ ASE +AL + G RD+ PGE+ ID + S A
Sbjct: 193 AARDPHGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLAIDADGVRSTRFAN 252
Query: 234 EKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALG 293
+ CVFEY+Y ARPDSTL G +V+ R +G LARE P E D+VI VP+SG AA+G
Sbjct: 253 PEPKGCVFEYVYLARPDSTLVGRSVHATRVDIGRRLAREHPVEADLVIGVPESGTPAAVG 312
Query: 294 FAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVR 351
+A ESGIP+ +GL+KN Y+GRTFI PS R L ++LKL+P+REV+ GKR+++VDDSIVR
Sbjct: 313 YAQESGIPFGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLREVIRGKRLIVVDDSIVR 372
Query: 352 GTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRS-------IED 404
G T +V+MLR+AGA EVHVRIASPP+R+PC+ GID T ELIA S +E
Sbjct: 373 GNTQRALVRMLREAGALEVHVRIASPPVRWPCFYGIDFATPAELIANAASQEHEGEMLEA 432
Query: 405 IRKEIGADSLAYLSIEGLKRAV--GTKNLCMACLTGEYP 441
+R IGADSL Y+S +G+ A LC AC G+YP
Sbjct: 433 VRHAIGADSLGYISQQGMIAATEQPASRLCSACFDGKYP 471
>sp|P52418|PUR1_SOYBN AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPAT) >gi|7433948|pir||T07158
amidophosphoribosyltransferase (EC 2.4.2.14) precursor -
soybean >gi|438899|gb|AAA73943.1| (L23833) glutamine
phosphoribosylpyrophosphate amidotransferase [Glycine
max]
Length = 569
Score = 360 bits (915), Expect = 1e-98
Identities = 214/450 (47%), Positives = 293/450 (64%), Gaps = 20/450 (4%)
Query: 8 REKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGI-SVWNGRIRTIKGHGLVSEVFDEN 65
RE+CG+ G+ + +A R L ALQHRGQEGAGI +V + ++++ G GLVS+VF+++
Sbjct: 78 REECGVVGIYGDPEASRLCSLALHALQHRGQEGAGIVAVHDNHLQSVTGVGLVSDVFEQS 137
Query: 66 SLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLR-RLYEG 121
L+ L AIGHVRYST+G L VQP +A+AHNG N+ LR RL
Sbjct: 138 KLSRLPGTSAIGHVRYSTAGQSMLKNVQPFLADYRFAAVAVAHNGNFVNYRSLRARLEHN 197
Query: 122 MGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRV--FEEVKGAYSILILFDGKIIAARD 179
G F+++ DTEV+ L+ + K +R V E ++GAYS++ + + K++A RD
Sbjct: 198 NGSIFNTTSDTEVV----LHLIATSKHRPFLLRIVDACEHLQGAYSLVFVTEDKLVAVRD 253
Query: 180 PVGFRPLVFGE--GDGYYFASEDSALRMF-GLETRDVLPGEVFVIDGESYESKVL-AREK 235
P GFRPLV G ASE AL + R+V PGEV V+D +S L + +
Sbjct: 254 PFGFRPLVMGRRTNGAVVLASETCALDLIEATYEREVYPGEVIVVDHTGIQSLCLVSHPE 313
Query: 236 HAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFA 295
C+FE+IYFA P+S + G +VY +R + G LA ESP E DVVIAVPDSG AALG+A
Sbjct: 314 PKQCIFEHIYFALPNSVVFGRSVYESRKKFGEILASESPVECDVVIAVPDSGVVAALGYA 373
Query: 296 HESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGT 353
++G+P+ +GLI++ Y+GRTFI PS R VKLKLSPV V+ GKRVV+VDDSIVRGT
Sbjct: 374 AKAGVPFQQGLIRSHYVGRTFIEPSQKIRDFGVKLKLSPVHAVLEGKRVVVVDDSIVRGT 433
Query: 354 TMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADS 413
T ++IV++L++AGA+EVH+RIA PPI CY G+D P+ ELI+ S+E+IRK IG+DS
Sbjct: 434 TSSKIVRLLKEAGAKEVHMRIACPPIVASCYYGVDTPSSEELISNRMSVEEIRKFIGSDS 493
Query: 414 LAYLSIEGLKRAVG--TKNLCMACLTGEYP 441
LA+L ++ LK +G N C AC +G+YP
Sbjct: 494 LAFLPLDKLKTLLGDDALNYCYACFSGKYP 523
>sp|Q55038|PUR1_SYNP7 AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|7433955|pir||S77612
amidophosphoribosyltransferase (EC 2.4.2.14) precursor -
Synechococcus sp. (strain PCC 7942)
>gi|974612|gb|AAA75107.1| (U33211) glutamine PRPP
amidotransferase [Synechococcus sp.]
Length = 493
Score = 360 bits (913), Expect = 3e-98
Identities = 202/450 (44%), Positives = 282/450 (61%), Gaps = 17/450 (3%)
Query: 9 EKCGIFGVSS--EDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDEN 65
E CG+F + + E+ R Y+GL ALQHRGQE AGI+V+ G R+ K GLVS+VFD
Sbjct: 25 EACGVFALYAPGEEVARMAYFGLYALQHRGQESAGIAVFEGDRVMLHKDMGLVSQVFDPE 84
Query: 66 SLN-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGM 122
L L ++A+GH RYST+GS ++ QP + +A+AHNG L N + LR+
Sbjct: 85 ILQQLQGSLAVGHTRYSTTGSSRIANAQPALLETRLGPVALAHNGNLVNTVELRQELLAK 144
Query: 123 GIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVG 182
+ ++ D+E+I + + ++ +D A+ +GA+S+ I + RDP G
Sbjct: 145 NHELTTTTDSELIAFAIMEAVAEGQDWRGAIESACRRSQGAFSLTIGTPEALYGTRDPNG 204
Query: 183 FRPLVFG--EGDG---YYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAREKH 236
RPLV G E +G Y +SE L + G + RD+ PGE+ I ES A
Sbjct: 205 IRPLVLGTLESNGQTRYVLSSETCGLDIIGADYVRDIAPGEMVRITDAGLESWTWAEAPQ 264
Query: 237 A-YCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFA 295
CVFE IYFARPDS +G ++Y R R+G LA+E+PA+ D+V+ VPDSG AA+GF+
Sbjct: 265 PKLCVFEMIYFARPDSLFHGESLYSYRRRIGQRLAKEAPADVDLVLGVPDSGIPAAIGFS 324
Query: 296 HESGIPYMEGLIKNRYIGRTFIMP--SGRGLKVKLKLSPVREVVNGKRVVLVDDSIVRGT 353
GIPY EGLIKNRY+GRTFI P S R +++KL+P+++V+ GKR+ ++DDSIVRGT
Sbjct: 325 EALGIPYAEGLIKNRYVGRTFIQPTQSMRETGIRMKLNPLKDVLAGKRIAIIDDSIVRGT 384
Query: 354 TMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADS 413
T ++VK LRDAGA EVH+RI+SPP+ +PC+ GID T+ +LIAA RS+ +I ++IG DS
Sbjct: 385 TSRKLVKALRDAGATEVHMRISSPPVTHPCFYGIDTDTQDQLIAATRSVSEITEQIGVDS 444
Query: 414 LAYLSIEGLKRAV--GTKNLCMACLTGEYP 441
LAYL+ +G+ A N C AC G YP
Sbjct: 445 LAYLTEQGMLEATRESIGNFCTACFNGRYP 474
>gb|AAG19793.1| (AE005064) amidophosphoribosyl-pyrophosphate amidotransferase; PurF
[Halobacterium sp. NRC-1]
Length = 490
Score = 360 bits (913), Expect = 3e-98
Identities = 209/453 (46%), Positives = 278/453 (61%), Gaps = 21/453 (4%)
Query: 9 EKCGIFG--VSSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDEN 65
EKCG+ G +S+ DA TYY L ALQHRGQE AGI +G + G GLV + FDE
Sbjct: 16 EKCGVVGASLSARDAALPTYYALYALQHRGQESAGIVAHDGFQQHQHVGMGLVGDAFDEA 75
Query: 66 SLN-LASNIAIGHVRYSTSGSLSE--VQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGM 122
++ L + AIGHVRY T+GS+ + QP V G L ++HNG L N LR
Sbjct: 76 DIDALHGSAAIGHVRYPTAGSVDKSCAQPFSVSFKGGALGLSHNGNLVNADELRADLAAS 135
Query: 123 GIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVG 182
G F S DTEVI + D +A+ R E + G+YS+ I+ D ++ RDP G
Sbjct: 136 GHAFTSDGDTEVIAHDLARNLLDA-DLVDAVERTMERIHGSYSLTIMHDDTVLGVRDPRG 194
Query: 183 FRPLVFGE-GDGYYFASEDSALRMFGLET-RDVLPGEVFVID--GESYESKVLA-REKHA 237
RPLV G DGY ASE +A+ G + RDV PGE V+D G + + L R+ A
Sbjct: 195 NRPLVLGTVEDGYVIASESAAIDTIGGDVVRDVRPGEAIVLDDDGTGFSAHQLVDRDTTA 254
Query: 238 YCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHE 297
+C FEY+YFARPDS ++ VY R +G +L E+ E DVV+ VPDSGR A G+A
Sbjct: 255 HCFFEYVYFARPDSVIDDELVYEVRRNLGRQLWHETGVESDVVVPVPDSGRAFASGYADA 314
Query: 298 -----SGIPYMEGLIKNRYIGRTFIMPS--GRGLKVKLKLSPVREVVNGKRVVLVDDSIV 350
S + + EGL+KNRY+GRTFIMP+ R V+LKL+P++ V G+ V ++DDSIV
Sbjct: 315 ATEDGSDVEFAEGLMKNRYVGRTFIMPTQEARERAVRLKLNPIKSTVEGQSVTIIDDSIV 374
Query: 351 RGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIG 410
RGTT +++V ++RDAGA EVHVRI +P I+ PCY GID+ TR ELIAA R+ ++I EIG
Sbjct: 375 RGTTSSQLVDLVRDAGATEVHVRIGAPQIQAPCYFGIDMATREELIAADRTADEIAAEIG 434
Query: 411 ADSLAYLSIEGLKRAVGTK--NLCMACLTGEYP 441
ADSL+YL + + A+G ++C C+TG YP
Sbjct: 435 ADSLSYLPLSAVTAAIGKSEADMCAGCVTGAYP 467
>sp|Q55621|PUR1_SYNY3 AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|7433956|pir||S76280
amidophosphoribosyltransferase (EC 2.4.2.14) precursor
[similarity] - Synechocystis sp. (strain PCC 6803)
>gi|1001507|dbj|BAA10132.1| (D64000)
amidophosphoribosyltransferase [Synechocystis sp.]
Length = 495
Score = 355 bits (901), Expect = 6e-97
Identities = 209/450 (46%), Positives = 279/450 (61%), Gaps = 17/450 (3%)
Query: 9 EKCGIFGV-SSEDAVRK-TYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEVFDEN 65
E CG+FG+ + E+AV K TY+GL ALQHRGQE AGI+ + G + K GLVS+VF E+
Sbjct: 27 EACGVFGIYAPEEAVAKLTYFGLYALQHRGQESAGIATFAGTTVHCHKDMGLVSQVFQES 86
Query: 66 SLN-LASNIAIGHVRYSTSGSLSEV--QPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGM 122
LN + +A+GH RYST+GS V QP + LA+AHNG L N LR
Sbjct: 87 KLNEMVGTLAVGHTRYSTTGSSHRVNAQPAVLPTRLGPLALAHNGNLVNTNQLREALAER 146
Query: 123 GIK-FHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPV 181
G + F ++ D+E+I ++ N + KD E GAYS++I II RDP
Sbjct: 147 GCEDFVTTTDSEMIAVAIANEVDKGKDWVEGTIAALTLCAGAYSLVIGTPEGIIGVRDPH 206
Query: 182 GFRPLVFG----EGDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAREK- 235
G RPLV G E Y ASE AL + G R V GE+ I S LA
Sbjct: 207 GIRPLVIGVLEEETPRYVLASETCALDIIGATYVRTVEAGELVHITESGLVSHRLAESAD 266
Query: 236 HAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFA 295
CVFE IYF+RPDS +N ++Y R R+G LA+ESP + D+V+ VPDSG AA+GF+
Sbjct: 267 RKLCVFEMIYFSRPDSVVNDESLYTYRMRIGKHLAKESPVDADLVMGVPDSGIPAAIGFS 326
Query: 296 HESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGT 353
SGIPY EGLIKNRY+GRTFI P+ R +++KL+P+++V+ GKR+++VDDSIVRGT
Sbjct: 327 QASGIPYAEGLIKNRYVGRTFIQPTQHMREHGIRMKLNPLKDVLAGKRIIIVDDSIVRGT 386
Query: 354 TMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADS 413
T +IV+ LR+AGA EVH+RI+SPP+ +PC+ GID ++ +LIAA ++ +I ++I DS
Sbjct: 387 TSRKIVRALREAGATEVHMRISSPPVTHPCFYGIDTDSQDQLIAARLTVAEIAEQIEVDS 446
Query: 414 LAYLSIEGLKRAVG--TKNLCMACLTGEYP 441
LAYLS EG+ G + C AC G YP
Sbjct: 447 LAYLSQEGMLLCTGEDISHFCSACFNGRYP 476
>sp|P52419|PUR1_VIGAC AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPAT) >gi|7433959|pir||T10792
amidophosphoribosyltransferase (EC 2.4.2.14) precursor -
moth bean (fragment) >gi|439105|gb|AAA73944.1| (L23834)
glutamine phosphoribosylpyrophosphate amidotransferase
[Vigna aconitifolia]
Length = 485
Score = 351 bits (892), Expect = 7e-96
Identities = 212/449 (47%), Positives = 289/449 (64%), Gaps = 20/449 (4%)
Query: 8 REKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGI-SVWNGRIRTIKGHGLVSEVFDEN 65
RE+CG+ G+ + +A R L ALQHRGQEGAGI +V + + G GLVS+VF+E
Sbjct: 16 REECGVVGIYGDPEASRLCSLALHALQHRGQEGAGIVAVHDNLFHQVNGVGLVSDVFNEA 75
Query: 66 SLN-LASNIAIGHVRYSTSG--SLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGM 122
L+ L + AIGHVRYST+G L VQP +A+AHNG N+ LR E
Sbjct: 76 KLSELPGSCAIGHVRYSTAGHSKLVNVQPFVAGYRFGSVAVAHNGNFVNYRSLRAKLEDN 135
Query: 123 GIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRV--FEEVKGAYSILILFDGKIIAARDP 180
G F+++ DTEV+ L+ + K +R V E +KGAYS++ L + K++A RD
Sbjct: 136 GSIFNTTSDTEVV----LHLIATSKHRPFLLRVVDACENLKGAYSLVFLTEDKLVAVRD- 190
Query: 181 VGFRPLVFG--EGDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLA-REKH 236
GFRPLV G + FASE AL + R+V PGEV V+D +S L ++
Sbjct: 191 FGFRPLVMGRRKNGAVVFASETCALDLIDATYEREVNPGEVVVVDHTGIQSLCLVTHQEP 250
Query: 237 AYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAH 296
C+FE+IYFA P+S + G +VY +R + G LA ESP E DVVIAVPDSG AALG+A
Sbjct: 251 KQCIFEHIYFALPNSVVFGRSVYESRRKFGEILATESPVECDVVIAVPDSGVVAALGYAA 310
Query: 297 ESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTT 354
++G+P+ +GLI++ ++GRTFI PS R VKLKL PVR V+ GKRVV+VDDSIVRGTT
Sbjct: 311 KAGVPFQQGLIRSHHVGRTFIEPSQKIRDFGVKLKLFPVRGVLEGKRVVVVDDSIVRGTT 370
Query: 355 MTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSL 414
++IV+++++AGA+EVH+RIA PPI CY G+D P++ ELI+ +E+IRK IG+DSL
Sbjct: 371 SSKIVRLIKEAGAKEVHMRIACPPIVASCYYGVDTPSKEELISNRMDVEEIRKFIGSDSL 430
Query: 415 AYLSIEGLKRAV--GTKNLCMACLTGEYP 441
A+L ++ LK + N C AC +G+YP
Sbjct: 431 AFLPLDTLKSLLEDDAPNYCYACFSGKYP 459
>sp|Q50028|PUR1_MYCLE AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|699224|gb|AAA62988.1| (U15182)
amino-phosphoribosyl transferase precursor
[Mycobacterium leprae] >gi|2076639|emb|CAB08437.1|
(Z95151) PurF [Mycobacterium leprae]
Length = 556
Score = 350 bits (888), Expect = 2e-95
Identities = 202/457 (44%), Positives = 280/457 (61%), Gaps = 24/457 (5%)
Query: 8 REKCGIFGV--SSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDE 64
RE+CG+FGV E + TY+GL ALQHRGQE AGI+V +G ++ K GLVS+VFDE
Sbjct: 55 REECGVFGVWAPGELVAKLTYFGLYALQHRGQEAAGIAVADGSQVLVFKDLGLVSQVFDE 114
Query: 65 NSLN-LASNIAIGHVRYSTSGSLS--EVQPLEVR-CCGYELAIAHNGTLTNFIPLRRLYE 120
+L + ++AIGH RYST+G + QP+ G +A+ HNG L N L
Sbjct: 115 QTLAAMEGHVAIGHCRYSTTGDTTWENAQPVFRNIAAGSGVALGHNGNLVNTAELAARAR 174
Query: 121 GMGI-----KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKII 175
G+ ++ D++++G + L H + +A + V+GA+ + + + +
Sbjct: 175 DAGLIAKRCPAPATTDSDILG-ALLAHGAADSTLEQAALELLPTVRGAFCLTFMDENTLY 233
Query: 176 AARDPVGFRPLVFGEGD-GYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAR 233
A RDP G RPL G D G+ ASE + L + G RD+ PGE+ ID + S A
Sbjct: 234 ACRDPYGVRPLSLGRLDRGWVVASETAGLDIVGASFVRDIEPGELLAIDADGVRSTRFAN 293
Query: 234 EKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALG 293
CVFEY+Y ARPDSTL G +V+ R +G LARE P E D+VI VP+SG AA+G
Sbjct: 294 PTPKGCVFEYVYLARPDSTLAGRSVHGTRVEIGRRLARECPVEADLVIGVPESGTPAAVG 353
Query: 294 FAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVR 351
+A ESGI Y +GL+KN Y+GRTFI PS R L ++LKL+P++EV+ GKR+++VDDS+VR
Sbjct: 354 YAQESGISYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSVVR 413
Query: 352 GTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIA-----AWRSIEDIR 406
G T +V+MLR+AGA E+HVRIASPP+++PC+ GID P+ ELIA +E +R
Sbjct: 414 GNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANVVADEEEMLEAVR 473
Query: 407 KEIGADSLAYLSIEGLKRA--VGTKNLCMACLTGEYP 441
+ IGAD+L Y+S+ G+ A LC AC G YP
Sbjct: 474 QGIGADTLGYISLRGMIAASEQPASRLCYACFDGRYP 510
>pir||A70401 amidophosphoribosyltransferase (EC 2.4.2.14) purF [similarity] -
Aquifex aeolicus >gi|2983634|gb|AAC07202.1| (AE000727)
amidophosphoribosyltransferase [Aquifex aeolicus]
Length = 465
Score = 350 bits (888), Expect = 2e-95
Identities = 209/452 (46%), Positives = 279/452 (61%), Gaps = 21/452 (4%)
Query: 11 CGIFGV-SSEDAVRKTYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEVFDENSLN 68
CG+ GV +S A + +LQHRGQE GIS + + I T+K G V E + L
Sbjct: 2 CGVAGVFNSPYAAEYALLMIYSLQHRGQESVGISSSDEKEIYTVKKPGRVLEAIKKEDLE 61
Query: 69 -LASNIAIGHVRYSTSGSLS--EVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIK 125
L +IAI HVRYST+G+ QPL ++A+ HNG L NF+ LR+ E GIK
Sbjct: 62 KLKGSIAIAHVRYSTAGNAGGFNAQPLVRETPLGKVAVVHNGNLVNFLTLRKELEDKGIK 121
Query: 126 FHSSVDTEVI------GISFLNH----YSQVKDEFEAMRRVFEEVKGAYSILILFDGKII 175
F+ + D+E+ G +++ + + KD + VKGAYS++ LF K++
Sbjct: 122 FNYNSDSELFLALLEEGRTYIPEGVTLHPEDKDFLPYIFYALSRVKGAYSLIYLFRDKLV 181
Query: 176 AARDPVGFRPLVFG-EGDGYYFASEDSALRMFGLET-RDVLPGEVFVIDGESYES-KVLA 232
ARDP GFRPL G + + ASE A + E R+V PGEV VID + S ++ +
Sbjct: 182 VARDPYGFRPLALGRKKNTILVASESCAFDILEAEFWREVKPGEVLVIDKKGKRSYRIFS 241
Query: 233 REKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAAL 292
+ A C+FE++YF+RPDS + G VY R MG +LARE E DVVI VPDSG AL
Sbjct: 242 SPRKAMCIFEFVYFSRPDSYIFGDWVYNVRKEMGRQLAREDNIEADVVIPVPDSGVVPAL 301
Query: 293 GFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIV 350
G+A E G+P+ GLI+N Y+GR+FI P+ R L+V +KLSP R V+ GKRV+++DDS+V
Sbjct: 302 GYAEEKGLPFEYGLIRNHYVGRSFIEPTPELRNLRVLMKLSPNRAVLQGKRVIVIDDSLV 361
Query: 351 RGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIG 410
RGTT RIV MLR AGA+E+H+RIASPP+ PCY GID PT+ ELIA IEDI K IG
Sbjct: 362 RGTTSKRIVSMLRRAGAKEIHMRIASPPVVGPCYYGIDTPTKEELIANKMPIEDIAKFIG 421
Query: 411 ADSLAYLSIEGLKRAVG-TKNLCMACLTGEYP 441
DSL YLS+EGL++ V ++ C AC + YP
Sbjct: 422 VDSLKYLSLEGLRKCVDKPEDFCDACFSLNYP 453
>gb|AAF18277.1| (AF088897) amidophosphoribosyltransferase [Zymomonas mobilis]
Length = 508
Score = 349 bits (887), Expect = 3e-95
Identities = 201/454 (44%), Positives = 288/454 (63%), Gaps = 24/454 (5%)
Query: 7 MREKCGIFGVSSED-AVRKTYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEVFDE 64
+ E+CG+FG+ D A GL ALQHRGQE AGI+ W+G+ + + G V+ FD
Sbjct: 33 LHEECGVFGIWGADTAAAVVALGLHALQHRGQEAAGITSWDGKNFHSRRAVGHVAGNFDR 92
Query: 65 NSL--NLASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYE 120
+ +L + AIGHVRY+T+G+ L VQPL AIAHNG ++N LR
Sbjct: 93 DDAIRSLPGSCAIGHVRYATTGASTLCNVQPLYAELVSGGFAIAHNGNISNAETLRHQLV 152
Query: 121 GMGIKFHSSVDTE-VIGISFLNHYSQVKDEF-EAMRRVFEEVKGAYSILILFDGKIIAAR 178
G F S+ DTE +I + + Y + D F +A++ +V+GAYS++ L +IA
Sbjct: 153 RHGSIFQSTSDTETIIHLVATSSYRSLLDRFIDALK----QVEGAYSLVCLTPEGMIACG 208
Query: 179 DPVGFRPLVFGE-GDGYYFASEDSALRMFG-LETRDVLPGEVFVIDGESYES-KVLAREK 235
DP+G RPLV G+ G+ + ASE AL + G R V PGE+ +I + +S ++K
Sbjct: 209 DPLGIRPLVLGKVGETFVVASETVALDIIGGTYIRQVEPGELIIISEKGLQSIHPFKKQK 268
Query: 236 HAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFA 295
C+FE++YF+RPDS + +VY R +G+ELARE+P + D+VI VPDSG AA+G+A
Sbjct: 269 PRPCIFEHVYFSRPDSLIGSTSVYSVRKSIGIELARENPVDADMVIPVPDSGTPAAIGYA 328
Query: 296 HESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGT 353
+S +P+ G+I++ Y+GRTFI P R L VKLK + R ++ GK++VLVDDSIVRGT
Sbjct: 329 QQSSLPFELGIIRSHYVGRTFIQPGDQVRHLGVKLKHNANRALIKGKKLVLVDDSIVRGT 388
Query: 354 TMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADS 413
T +I++MLRDAGA+E+H+RIASPP R+ C+ G+D P R +L+AA ++E + + IGADS
Sbjct: 389 TSVKIIRMLRDAGAKEIHLRIASPPTRHSCFYGVDTPERAKLLAAKMTVEQMAEYIGADS 448
Query: 414 LAYLSIEGLKRAVGTK-------NLCMACLTGEY 440
LA++S++GL RAVG + C AC TG Y
Sbjct: 449 LAFISMDGLYRAVGEEARNDAQPQYCDACFTGAY 482
>dbj|BAA89439.1| (AB003158) amidophosphoribosyl transferase [Corynebacterium
ammoniagenes]
Length = 490
Score = 348 bits (884), Expect = 6e-95
Identities = 205/458 (44%), Positives = 283/458 (61%), Gaps = 26/458 (5%)
Query: 8 REKCGIFGV--SSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDE 64
RE+CG+FGV ED TY+GL ALQHRGQE AGI V +G R+ K GLVS +FDE
Sbjct: 12 REECGVFGVWAPGEDVATLTYFGLFALQHRGQEAAGIGVGDGDRLVVFKDMGLVSNIFDE 71
Query: 65 NSLN-LASNIAIGHVRYSTSGSL--SEVQPL-EVRCCGYELAIAHNGTLTNFIPLRRLYE 120
+ LN L ++ +GH RYST+G S VQP+ G ++A+ HNG L N+ LR
Sbjct: 72 SILNSLHGSVGVGHTRYSTAGGKEWSNVQPMFNTTSNGVDIALCHNGNLVNYQELRDEAV 131
Query: 121 GMGI--KFHSSVDTEVIGISFLNH-YSQVKDEFEAMRRVFEEVKGAYSILILFDGKII-A 176
+G+ + S+ +I + L H + F+A +++ +KGA+ L DGK + A
Sbjct: 132 ALGLYRENEKSLSDSMIMTALLAHGVGEGNSVFDAAKQLLPSIKGAFC-LTFTDGKTLYA 190
Query: 177 ARDPVGFRPLVFGE-GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLARE 234
ARDP G RPLV G G+ ASE AL + G + R+V PGE+ ++ S+ A
Sbjct: 191 ARDPHGVRPLVIGRLAQGWVVASETCALDIVGAQFIREVEPGELISVNEAGIHSEKFAEP 250
Query: 235 KHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPA-EGDVVIAVPDSGRTAALG 293
K CVFEY+Y ARPD+ + G NV+ R +G LA+ PA E D+VI VP+SG AA+G
Sbjct: 251 KRQGCVFEYVYLARPDTVIKGRNVHATRVDIGRALAKSHPAPEADMVIPVPESGNPAAVG 310
Query: 294 FAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVR 351
+A ESG+ + GL+KN Y+GRTFI P+ R L ++LKL+P+REV+ GK +V+VDDSIVR
Sbjct: 311 YARESGLTFAHGLVKNAYVGRTFIQPTQTLRQLGIRLKLNPLREVIEGKSLVVVDDSIVR 370
Query: 352 GTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIED------- 404
G T +V+MLR+AGA EVHVRIASPP+++PC+ GID + ELIA + +D
Sbjct: 371 GNTQRALVRMLREAGAAEVHVRIASPPVKWPCFYGIDFASPGELIANIKPSDDPQVVTDA 430
Query: 405 IRKEIGADSLAYLSIEGLKRAV--GTKNLCMACLTGEY 440
+ + IGADSL ++S++ + A +LC AC G Y
Sbjct: 431 VCEAIGADSLGFVSVDEMVEATHQPINSLCTACFDGNY 468
>emb|CAA62633.1| (X91252) amidophosphoribosyltransferase [Corynebacterium
ammoniagenes]
Length = 490
Score = 346 bits (879), Expect = 2e-94
Identities = 204/458 (44%), Positives = 282/458 (61%), Gaps = 26/458 (5%)
Query: 8 REKCGIFGV--SSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDE 64
RE+CG+FGV ED TY+GL ALQHRGQE AGI V +G R+ K GLVS +FDE
Sbjct: 12 REECGVFGVWAPGEDVATLTYFGLFALQHRGQEAAGIGVGDGDRLVVFKNMGLVSNIFDE 71
Query: 65 NSLN-LASNIAIGHVRYSTSGSL--SEVQPL-EVRCCGYELAIAHNGTLTNFIPLRRLYE 120
+ LN L ++ +GH RYST+G S VQP+ G ++A+ HNG L N+ LR
Sbjct: 72 SILNSLHGSVGVGHTRYSTAGGKEWSNVQPMFNTTSNGVDIALCHNGNLVNYQELRDEAV 131
Query: 121 GMGI--KFHSSVDTEVIGISFLNH-YSQVKDEFEAMRRVFEEVKGAYSILILFDGKII-A 176
+G+ + S+ +I + L H + F+A +++ +KGA+ L DGK + A
Sbjct: 132 ALGLYRENEKSLSDSMIMTALLAHGVGEGNSVFDAAKQLLPSIKGAFC-LTFTDGKTLYA 190
Query: 177 ARDPVGFRPLVFGE-GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLARE 234
ARDP G RPLV G G+ ASE AL + + R+V PGE+ ++ S+ A
Sbjct: 191 ARDPHGVRPLVIGRLAQGWVVASETCALDIVSAQFIREVEPGELISVNEAGIHSEKFAEP 250
Query: 235 KHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPA-EGDVVIAVPDSGRTAALG 293
K CVFEY+Y ARPD+ + G NV+ R +G LA+ PA E D+VI VP+SG AA+G
Sbjct: 251 KRQGCVFEYVYLARPDTVIKGRNVHATRVDIGRALAKSHPAPEADMVIPVPESGNPAAVG 310
Query: 294 FAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVR 351
+A ESG+ + GL+KN Y+GRTFI P+ R L ++LKL+P+REV+ GK +V+VDDSIVR
Sbjct: 311 YARESGLTFAHGLVKNAYVGRTFIQPTQTLRQLGIRLKLNPLREVIEGKSLVVVDDSIVR 370
Query: 352 GTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIED------- 404
G T +V+MLR+AGA EVHVRIASPP+++PC+ GID + ELIA + +D
Sbjct: 371 GNTQRALVRMLREAGAAEVHVRIASPPVKWPCFYGIDFASPGELIANIKPSDDPQVVTDA 430
Query: 405 IRKEIGADSLAYLSIEGLKRAV--GTKNLCMACLTGEY 440
+ + IGADSL ++S++ + A +LC AC G Y
Sbjct: 431 VCEAIGADSLGFVSVDEMVEATHQPINSLCTACFDGNY 468
>sp|P28173|PUR1_CHICK AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPAT) >gi|104529|pir||A38337
amidophosphoribosyltransferase (EC 2.4.2.14) precursor -
chicken >gi|211825|gb|AAA62736.1| (M60069) glutamine
phosphoribosylpyrophosphate amidotransferase [Gallus
gallus]
Length = 510
Score = 343 bits (871), Expect = 2e-93
Identities = 211/504 (41%), Positives = 282/504 (55%), Gaps = 66/504 (13%)
Query: 6 GMREKCGIFGVSSE-------DAVRKTYYGLIALQHRGQEGAGISVWNGR----IRTIKG 54
G+RE+CG+FG + D GL+ LQHRGQE AGI +G + KG
Sbjct: 7 GIREECGVFGCIAAGVWPTELDVPHVITLGLVGLQHRGQESAGIVTSDGESSQAFKVHKG 66
Query: 55 HGLVSEVFDENSLN--LASNIAIGHVRYSTSG--SLSEVQPLEVRCCGYELAIAHNGTLT 110
GL++ VF+ +SL SN+ IGH RYSTSG L QP V ++A+AHNG LT
Sbjct: 67 MGLINHVFNADSLKKLYVSNLGIGHTRYSTSGISELQNCQPFVVETLHGKIAVAHNGELT 126
Query: 111 NFIPLRRLYEGMGIKFHSSVDTEVIG--ISFLN--HYSQVKDEFEAMRRVFEEVKGAYSI 166
N + LRR G+ +S D+E+I ++F D ++ + E +YS+
Sbjct: 127 NAVRLRRKLMRHGVGLSTSSDSELITQLLAFTPPLENDDTADWVARIKNLMNETPTSYSL 186
Query: 167 LILFDGKIIAARDPVGFRPLVFG----------------EGDGYYFASEDSALRMFGLET 210
LI+ I A RDP G RPL G E +G+ +SE + G E
Sbjct: 187 LIMHKDIIYAVRDPYGNRPLCIGRLIPVGDINGKGKDNSETEGWVVSSESCSFLSIGAEY 246
Query: 211 -RDVLPGEVFVIDGESYES-KVLAR---EKHAYCVFEYIYFARPDSTLNGINVYCARYRM 265
R+VLPGE+ I ++ V+ R + A+C+FEY+YFARPDS G VY R R
Sbjct: 247 YREVLPGEIVKISRYDVQTLDVVPRPEGDPSAFCIFEYVYFARPDSIFEGQMVYSVRRRC 306
Query: 266 GVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGR--G 323
G +LA E+P E D+V VP+S AALG+A + G+PY+E L KNRY+GRTFI P+ R
Sbjct: 307 GQQLAIEAPVEADLVSTVPESATPAALGYAQKCGLPYVEVLCKNRYVGRTFIQPNMRLRQ 366
Query: 324 LKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPC 383
L V K + + GKRVV++DDSIVRG T++ I+K+LR++GA+EVH+R+ASPPIR+PC
Sbjct: 367 LGVAKKFGVLSDNFKGKRVVIIDDSIVRGNTISPIIKLLRESGAKEVHIRVASPPIRFPC 426
Query: 384 YMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGL--------------------- 422
YMGI+IPT+ ELIA D+ IGADS+ YLS+EGL
Sbjct: 427 YMGINIPTKEELIANRPEFHDLANYIGADSVVYLSVEGLVSSVQESIKARKENENSLKTQ 486
Query: 423 KRAVGTKNLCMACLTGEYP---EW 443
K VG C ACLTG+YP EW
Sbjct: 487 KSRVGKIGHCTACLTGDYPVELEW 510
>gb|AAF54163.1| (AE003676) Prat gene product [Drosophila melanogaster]
Length = 511
Score = 342 bits (868), Expect = 5e-93
Identities = 212/494 (42%), Positives = 282/494 (56%), Gaps = 57/494 (11%)
Query: 3 KVRGMREKCGIFGV-------SSEDAVRKTYYGLIALQHRGQEGAGISVWNGR----IRT 51
++ G+ +CG+FG + D GL+ALQHRGQE AGI+ G+
Sbjct: 11 ELTGLTHECGVFGAIACGDWPTQMDIAHVICLGLVALQHRGQESAGIATSEGKCSKNFNV 70
Query: 52 IKGHGLVSEVFDENSLN-LASNIAIGHVRYSTSGSLSEV--QPLEVRCCGYELAIAHNGT 108
KG G++S +F+++S+ L N+ IGH RYST+G V QP EV LA+AHNG
Sbjct: 71 HKGMGMISTLFNDDSMKKLRGNLGIGHTRYSTAGGSGVVNCQPFEVHTTHGALALAHNGE 130
Query: 109 LTNFIPLRR--LYEGMGIKFHSSVDTEVIGISFLNHYSQVKD----EFEAMRRVFEEVKG 162
L N LRR L G+G+ HS D+E+I S V + + A R F +
Sbjct: 131 LVNNESLRREVLARGVGLSTHS--DSELIAQSLCCAPEDVSELDGPNWPARIRHFMMLAP 188
Query: 163 -AYSILILFDGKIIAARDPVGFRPLVFGE---------------GDGYYFASEDSALRMF 206
+YS++I+ KI A RD G RPL G+ DG+ +SE
Sbjct: 189 LSYSLVIMLKDKIYAVRDTYGNRPLCIGKIVPINAGHGNNLDTPADGWVVSSESCGFLSI 248
Query: 207 GLE-TRDVLPGEVFVIDGESYESKVLAR----EKHAYCVFEYIYFARPDSTLNGINVYCA 261
G R+V PGE+ + Y + + ++ A+C+FEY+YFAR DS G VY
Sbjct: 249 GARYVREVEPGEIVELSRSGYRTVDIVERPDFKRMAFCIFEYVYFARGDSIFEGQMVYTV 308
Query: 262 RYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG 321
R + G +L RE+P E D+V +VP+SG AA G+A ESGI + E L +NRY+GRTFI PS
Sbjct: 309 RLQCGRQLWREAPVEADIVSSVPESGTAAAHGYARESGIEFAEVLCRNRYVGRTFIQPST 368
Query: 322 R--GLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPI 379
R L V K + E V GKR+VL+DDSIVRG T+ I+K+LRDAGAREVH+RIASPP+
Sbjct: 369 RLRQLGVAKKFGALSENVAGKRLVLIDDSIVRGNTIGPIIKLLRDAGAREVHIRIASPPL 428
Query: 380 RYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRAVGTKNL-------- 431
+YPCYMGI+IPTR ELIA + + + + +GADSLAYLS+EGL AV K+
Sbjct: 429 QYPCYMGINIPTREELIANKLNPDQLARHVGADSLAYLSVEGLVEAVQLKHRDAGDSKSK 488
Query: 432 ----CMACLTGEYP 441
C ACLTGEYP
Sbjct: 489 GTGHCTACLTGEYP 502
>gb|AAK40941.1| Amidophosphoribosyltransferase (glutamine
phosphoribosylpyrophosphate amidotransferase) (ATase)
(GPAT) (purF-1) [Sulfolobus solfataricus]
Length = 450
Score = 340 bits (864), Expect = 1e-92
Identities = 205/447 (45%), Positives = 275/447 (60%), Gaps = 28/447 (6%)
Query: 7 MREKCGIFGVSS--EDAVRKTYYGLIALQHRGQEGAGIS-VWNGRIRTIKGHGLVSEVFD 63
+R+KCG+F VSS E ++ G+ LQHRGQE AGI+ NG I TIKG GLV EVF
Sbjct: 4 IRDKCGVFAVSSPKEVNIQLVVEGIRLLQHRGQESAGIAYAENGEILTIKGSGLVDEVFK 63
Query: 64 ENSLNLASNIAIGHVRYSTSG--SLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
EN LN IGHVRYSTSG S+ E QPL ++ +A NGT++N+
Sbjct: 64 EN-LNKFIKNGIGHVRYSTSGKSSIEEAQPLG----DSKIVVAFNGTISNYYQFGSF--- 115
Query: 122 MGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILF-DGKIIAARDP 180
VDTE I F + + ++ + V G YS+ IL D +I+ RDP
Sbjct: 116 -------RVDTEFI-YKFFKQKLAFRSIPDTVKEFMKVVDGGYSVAILLNDEEIVVFRDP 167
Query: 181 VGFRPLVFGEGDGYYF-ASEDSALRMFGLET-RDVLPGEVFVI-DGESYESKVLAREK-H 236
GF P+V G +G +SEDS +R G + +LP E+ ++ +G+ KV+ EK +
Sbjct: 168 KGFHPVVLGFLEGSLIVSSEDSVIRQLGGSVLKHILPSEMIIMKNGKILYDKVIYEEKNY 227
Query: 237 AYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAH 296
A C FEYIYFARPDS ++G +VY AR R+G LA + PA GD+V+ VPDS R ALGF+
Sbjct: 228 ATCSFEYIYFARPDSNIDGHSVYLARIRLGELLAEKHPANGDIVVPVPDSSRPIALGFSR 287
Query: 297 ESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTT 354
+S IP E L++ R+FIMP+ R ++ K V + V GKR+VL+DDSIVRG T
Sbjct: 288 KSHIPLEEPLVRTISSVRSFIMPTQDKRNEVLEEKFGVVADAVRGKRIVLIDDSIVRGNT 347
Query: 355 MTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSL 414
M RI+ MLR AGA+E+HVRI SP I+YPCYMGID P R ELIA +S ++I E+ ADS+
Sbjct: 348 MKRIITMLRKAGAKEIHVRIGSPMIKYPCYMGIDFPKREELIAHNKSEKEIGNELNADSI 407
Query: 415 AYLSIEGLKRAVGTKNLCMACLTGEYP 441
+LS+E + + +G ++LC AC +G YP
Sbjct: 408 EFLSVEEMLQGIGRRDLCNACFSGIYP 434
>emb|CAB57669.1| (Y18930) amidophosphoribosyltransferase (ATASE), (glutamine
phosphoribosylpyrophosphate amidotransferase)
[Sulfolobus solfataricus]
Length = 450
Score = 340 bits (864), Expect = 1e-92
Identities = 205/447 (45%), Positives = 275/447 (60%), Gaps = 28/447 (6%)
Query: 7 MREKCGIFGVSS--EDAVRKTYYGLIALQHRGQEGAGIS-VWNGRIRTIKGHGLVSEVFD 63
+R+KCG+F VSS E ++ G+ LQHRGQE AGI+ NG I TIKG GLV EVF
Sbjct: 4 IRDKCGVFAVSSPKEVNIQLVVEGIRLLQHRGQESAGIAYAENGEILTIKGSGLVDEVFK 63
Query: 64 ENSLNLASNIAIGHVRYSTSG--SLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
EN LN IGHVRYSTSG S+ E QPL ++ +A NGT++N+
Sbjct: 64 EN-LNKFIKNGIGHVRYSTSGKSSIEEAQPLG----DSKIVVAFNGTISNYYQFGSF--- 115
Query: 122 MGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILF-DGKIIAARDP 180
VDTE I F + + ++ + V G YS+ IL D +I+ RDP
Sbjct: 116 -------RVDTEFI-YKFFKQKLAFRSIPDTVKEFMKVVDGGYSVAILLNDEEIVVFRDP 167
Query: 181 VGFRPLVFGEGDGYYF-ASEDSALRMFGLET-RDVLPGEVFVI-DGESYESKVLAREK-H 236
GF P+V G +G +SEDS +R G + +LP E+ ++ +G+ KV+ EK +
Sbjct: 168 KGFHPVVLGFLEGSLIVSSEDSVIRQLGGSVLKHILPSEMIIMKNGKILYDKVIYEEKNY 227
Query: 237 AYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAH 296
A C FEYIYFARPDS ++G +VY AR R+G LA + PA GD+V+ VPDS R ALGF+
Sbjct: 228 ATCSFEYIYFARPDSNIDGHSVYLARIRLGELLAEKHPANGDIVVPVPDSSRPIALGFSR 287
Query: 297 ESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTT 354
+S IP E L++ R+FIMP+ R ++ K V + V GKR+VL+DDSIVRG T
Sbjct: 288 KSHIPLEEPLVRTISSVRSFIMPTQDKRNEVLEEKFGVVADAVRGKRIVLIDDSIVRGNT 347
Query: 355 MTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSL 414
M RI+ MLR AGA+E+HVRI SP I+YPCYMGID P R ELIA +S ++I E+ ADS+
Sbjct: 348 MKRIITMLRKAGAKEIHVRIGSPMIKYPCYMGIDFPKREELIAHNKSEKEIGNELNADSI 407
Query: 415 AYLSIEGLKRAVGTKNLCMACLTGEYP 441
+LS+E + + +G ++LC AC +G YP
Sbjct: 408 EFLSVEEMLQGIGRRDLCNACFSGIYP 434
>sp|Q27601|PUR1_DROME AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPAT) >gi|1085154|pir||S47860
amidophosphoribosyltransferase (EC 2.4.2.14) precursor -
fruit fly (Drosophila melanogaster)
>gi|3213199|gb|AAC39084.1| (AF017096)
prophosphoribosylamidotransferase [Drosophila
melanogaster]
Length = 511
Score = 339 bits (861), Expect = 3e-92
Identities = 211/494 (42%), Positives = 281/494 (56%), Gaps = 57/494 (11%)
Query: 3 KVRGMREKCGIFGV-------SSEDAVRKTYYGLIALQHRGQEGAGISVWNGR----IRT 51
++ G+ +CG+FG + D GL+ALQHRGQE AGI+ G+
Sbjct: 11 ELTGLTHECGVFGAIACGDWPTQMDIAHVICLGLVALQHRGQESAGIATSEGKCSKNFNV 70
Query: 52 IKGHGLVSEVFDENSLN-LASNIAIGHVRYSTSGSLSEV--QPLEVRCCGYELAIAHNGT 108
KG G++S +F+++S+ L N+ IGH RYST+G V QP V LA+AHNG
Sbjct: 71 HKGMGMISTLFNDDSMKKLRGNLGIGHTRYSTAGGSGVVNCQPFVVHTTHGALALAHNGE 130
Query: 109 LTNFIPLRR--LYEGMGIKFHSSVDTEVIGISFLNHYSQVKD----EFEAMRRVFEEVKG 162
L N LRR L G+G+ HS D+E+I S V + + A R F +
Sbjct: 131 LVNNESLRREVLARGVGLSSHS--DSELIAQSLCCAPEDVSELDGPNWPARIRHFMMLAP 188
Query: 163 -AYSILILFDGKIIAARDPVGFRPLVFGE---------------GDGYYFASEDSALRMF 206
+YS++I+ KI A RD G RPL G+ DG+ +SE
Sbjct: 189 LSYSLVIMLKDKIYAVRDTYGNRPLCIGKIVPINAGHGNNLDTPADGWVVSSESCGFLSI 248
Query: 207 GLE-TRDVLPGEVFVIDGESYESKVLAR----EKHAYCVFEYIYFARPDSTLNGINVYCA 261
G R+V PGE+ + Y + + ++ A+C+FEY+YFAR DS G VY
Sbjct: 249 GARYVREVEPGEIVELSRSGYRTVDIVERPDFKRMAFCIFEYVYFARGDSIFEGQMVYTV 308
Query: 262 RYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG 321
R + G +L RE+P E D+V +VP+SG AA G+A ESGI + E L +NRY+GRTFI PS
Sbjct: 309 RLQCGRQLWREAPVEADIVSSVPESGTAAAHGYARESGIEFAEVLCRNRYVGRTFIQPST 368
Query: 322 R--GLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPI 379
R L V K + E V GKR+VL+DDSIVRG T+ I+K+LRDAGAREVH+RIASPP+
Sbjct: 369 RLRQLGVAKKFGALSENVAGKRLVLIDDSIVRGNTIGPIIKLLRDAGAREVHIRIASPPL 428
Query: 380 RYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRAVGTKNL-------- 431
+YPCYMGI+IPTR ELIA + + + + +GADSLAYLS+EGL AV K+
Sbjct: 429 QYPCYMGINIPTREELIANKLNPDQLARHVGADSLAYLSVEGLVEAVQLKHRDAGDSKSK 488
Query: 432 ----CMACLTGEYP 441
C ACLTGEYP
Sbjct: 489 GTGHCTACLTGEYP 502
>gb|AAF50639.2| (AE003561) CG10078 gene product [alt 1] [Drosophila melanogaster]
>gi|10728097|gb|AAF50638.2| (AE003561) CG10078 gene
product [alt 2] [Drosophila melanogaster]
Length = 470
Score = 329 bits (835), Expect = 4e-89
Identities = 202/459 (44%), Positives = 267/459 (58%), Gaps = 47/459 (10%)
Query: 28 GLIALQHRGQEGAGISVWNGR----IRTIKGHGLVSEVFDENSLN-LASNIAIGHVRYST 82
GL+ALQHRGQE AGI G+ KG G+++ +F++ ++ L N+ IGH RYST
Sbjct: 5 GLVALQHRGQESAGIVTSLGKSSKNFSVHKGMGMINNLFNDEAIRKLKGNLGIGHTRYST 64
Query: 83 SGSLSEV--QPLEVRCCGYELAIAHNGTLTNFIPLRR--LYEGMGIKFHSSVDTEVIGIS 138
+ + V QP V LAIAHNG L N LRR L G+G+ HS D+E+I S
Sbjct: 65 AAASEVVNCQPFVVHTAHGALAIAHNGELVNCESLRREVLERGVGLSTHS--DSELIAQS 122
Query: 139 FLNHYSQVKDE----FEAMRRVFEEVKG-AYSILILFDGKIIAARDPVGFRPLVFGE--- 190
V + + A R F + +YS++++ KI A RD G RPL G+
Sbjct: 123 LCCAPEDVSEHDGPNWPARIRHFMTLAPLSYSLVVMHKDKIYAVRDSYGNRPLCLGKIVP 182
Query: 191 ------------GDGYYFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAR---- 233
+G+ +SE G R+V PGE+ + Y + +
Sbjct: 183 VDAGHANINDQLAEGWVVSSESCGFLSIGARYVREVEPGEIIELSRNGYRTVDIVERPDY 242
Query: 234 EKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALG 293
++ A+C+FEY+YFAR DS G VY AR + G +LARESP + D+V +VP+SG AA G
Sbjct: 243 KRMAFCIFEYVYFARSDSMFEGQMVYSARLQCGRQLARESPLDADLVSSVPESGTAAAHG 302
Query: 294 FAHESGIPYMEGLIKNRYIGRTFIMPSGR--GLKVKLKLSPVREVVNGKRVVLVDDSIVR 351
+A ESG+P+ E L KNRY+GRTFI PS R L V K + + V GKR+VLVDDSIVR
Sbjct: 303 YARESGLPFGEVLCKNRYVGRTFIQPSTRLRQLGVAKKFGALAQNVEGKRIVLVDDSIVR 362
Query: 352 GTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGA 411
G T+ I+K+LRDAGA EVH+RIASPP++YPCYMGI+IPTR ELIA + + + +GA
Sbjct: 363 GNTIGPIIKLLRDAGATEVHIRIASPPLQYPCYMGINIPTREELIANKLNADQLADHVGA 422
Query: 412 DSLAYLSIEGLKRAVGTK---------NLCMACLTGEYP 441
DSLAYLS+EGL +AV C ACLTGEYP
Sbjct: 423 DSLAYLSVEGLVKAVQMNKAHVNPLKAGYCTACLTGEYP 461
>sp|P77935|PUR1_RHIET AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|1498756|gb|AAB06461.1| (U65392)
amidophosphoribosyltransferase PurF [Rhizobium etli]
Length = 498
Score = 324 bits (823), Expect = 9e-88
Identities = 212/464 (45%), Positives = 283/464 (60%), Gaps = 34/464 (7%)
Query: 7 MREKCGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGH-GLVSEVFDE 64
+ E+CG+FG+ DA T GL ALQHRGQE AGI ++G+ + H GLV + +
Sbjct: 18 LHEECGVFGILGHPDAAALTALGLHALQHRGQEAAGIVSFDGKRFYQERHMGLVGDHYT- 76
Query: 65 NSLNLA---SNIAIGHVRYSTSGSLS--EVQPLEVRCCGYELAIAHNGTLTNFIPLRRLY 119
N + LA +I+IGH RYST+G ++ VQPL +AIAHNG TN + LRR
Sbjct: 77 NPMTLARLPGSISIGHTRYSTTGEVAMRNVQPLFAELEEGGIAIAHNGNFTNGLTLRRQI 136
Query: 120 EGMGIKFHSSVDTEVI-GISFLNHYSQVKDEF-EAMRRVFEEVKGAYSILILFDGKIIAA 177
G S+ DTEV+ + + ++ D F +A+R +++G YS+L + K+IAA
Sbjct: 137 IATGAICQSTSDTEVVLHLIARSRHASTSDRFIDAIR----QMEGGYSMLAMTRTKLIAA 192
Query: 178 RDPVGFRPLVFGEGDGY-YFASEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAREK 235
P G RPLV GE DG F SE AL + G + RDV GEV + + + S + K
Sbjct: 193 SHPTGIRPLVMGELDGKPIFCSETCALDIIGAKFIRDVENGEVIICEIQPDGSISIDARK 252
Query: 236 HA------YCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRT 289
+ C+FEY+YFARPDS + G NVY R MG+ LA+ESP + DVV+ VPD G +
Sbjct: 253 PSKPQPERLCLFEYVYFARPDSVVGGRNVYTTRKNMGMNLAKESPVDADVVVPVPDGGTS 312
Query: 290 AALGFAHESGIP--YMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLV 345
AA G+A ESGIP Y G+I+N Y+GRTFI P+ R VKLK S R ++ GKRVVLV
Sbjct: 313 AAGGYAQESGIPFEYEYGIIRNHYVGRTFIEPTQQIRAFGVKLKHSANRAMIEGKRVVLV 372
Query: 346 DDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIA-AWRSIED 404
DDSIVRGTT +IV+M+R+AGAREVH+R+ASP I + + G PT +L+A + +E
Sbjct: 373 DDSIVRGTTSLKIVQMIREAGAREVHIRVASPMIFFRDFYGSIRPTPDKLLANQYADVEA 432
Query: 405 IRKEIGADSLAYLSIEGLKRAVGTKNLCMA-------CLTGEYP 441
+ K IGADSLA+LSI GL RAVG ++ A TG+YP
Sbjct: 433 MAKYIGADSLAFLSINGLYRAVGGEDRNPARPQFTDHYFTGDYP 476
>gi|4505979 phosphoribosyl pyrophosphate amidotransferase [Homo sapiens]
>gi|548638|sp|Q06203|PUR1_HUMAN
AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPAT) >gi|219459|dbj|BAA02903.1| (D13757)
amidophosphoribosyltransferase [Homo sapiens]
Length = 517
Score = 324 bits (822), Expect = 1e-87
Identities = 202/511 (39%), Positives = 284/511 (55%), Gaps = 73/511 (14%)
Query: 6 GMREKCGIFGVSSE-------DAVRKTYYGLIALQHRGQEGAGISVWNGR----IRTIKG 54
G+RE+CG+FG + D GL+ LQHRGQE AGI +G ++ KG
Sbjct: 7 GIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKG 66
Query: 55 HGLVSEVFDENSLN--LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLT 110
GLV+ VF E++L SN+ IGH RY+T+G L QP V ++A+AHNG L
Sbjct: 67 MGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELV 126
Query: 111 NFIPLRRLYEGMGIKFHSSVDTEVIGISFLNHYSQVKDE----FEAMRRVFEEVKGAYSI 166
N LR+ GI +S D+E+I Q +D+ ++ + +E AYS+
Sbjct: 127 NAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPTAYSL 186
Query: 167 LILFDGKIIAARDPVGFRPLVFG----------------EGDGYYFASEDSALRMFGLET 210
LI+ I A RDP G RPL G E +G+ +SE + G
Sbjct: 187 LIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARY 246
Query: 211 -RDVLPGEVFVIDGESYES-KVLAREKH---AYCVFEYIYFARPDSTLNGINVYCARYRM 265
R+VLPGE+ I + ++ +++R + A+C+FEY+YFARPDS VY RYR
Sbjct: 247 YREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRC 306
Query: 266 GVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGR--G 323
G +LA E+P + D+V VP+S AAL +A + G+PY+E L KNRY+GRTFI P+ R
Sbjct: 307 GQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQ 366
Query: 324 LKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPC 383
L V K + + GKR+VLVDDSIVRG T++ I+K+L+++GA+EVH+R+ASPPI+YPC
Sbjct: 367 LGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPC 426
Query: 384 YMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRAV--GTK------------ 429
+MGI+IPT+ ELIA + + + +GA+S+ YLS+EGL +V G K
Sbjct: 427 FMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKEKKHDIM 486
Query: 430 --------------NLCMACLTGEYP---EW 443
C ACLTG+YP EW
Sbjct: 487 IQENGNGLECFEKSGHCTACLTGKYPVELEW 517
>pir||A53342 amidophosphoribosyltransferase (EC 2.4.2.14) precursor - human
>gi|404861|gb|AAC27345.1| (U00238) glutamine PRPP
amidotransferase [Homo sapiens]
Length = 517
Score = 324 bits (821), Expect = 2e-87
Identities = 201/511 (39%), Positives = 284/511 (55%), Gaps = 73/511 (14%)
Query: 6 GMREKCGIFGVSSE-------DAVRKTYYGLIALQHRGQEGAGISVWNGR----IRTIKG 54
G+RE+CG+FG + D GL+ LQHRGQE AGI +G ++ KG
Sbjct: 7 GIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKG 66
Query: 55 HGLVSEVFDENSLN--LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLT 110
GLV+ VF E++L SN+ IGH RY+T+G L QP V ++A+AHNG L
Sbjct: 67 MGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELV 126
Query: 111 NFIPLRRLYEGMGIKFHSSVDTEVIGISFLNHYSQVKDE----FEAMRRVFEEVKGAYSI 166
N LR+ GI +S D+E+I Q +D+ ++ + +E AYS+
Sbjct: 127 NAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPTAYSL 186
Query: 167 LILFDGKIIAARDPVGFRPLVFG----------------EGDGYYFASEDSALRMFGLET 210
LI+ I A RDP G RPL G E +G+ +SE + G
Sbjct: 187 LIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARY 246
Query: 211 -RDVLPGEVFVIDGESYES-KVLAREKH---AYCVFEYIYFARPDSTLNGINVYCARYRM 265
R+VLPGE+ I + ++ +++R + A+C+FEY+YFARPDS VY RYR
Sbjct: 247 YREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRC 306
Query: 266 GVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGR--G 323
G +LA E+P + D+V VP+S AAL +A + G+PY+E L KNRY+GRTFI P+ R
Sbjct: 307 GQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQ 366
Query: 324 LKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPC 383
L + K + + GKR+VLVDDSIVRG T++ I+K+L+++GA+EVH+R+ASPPI+YPC
Sbjct: 367 LGIAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPC 426
Query: 384 YMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRAV--GTK------------ 429
+MGI+IPT+ ELIA + + + +GA+S+ YLS+EGL +V G K
Sbjct: 427 FMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKEKKHDIM 486
Query: 430 --------------NLCMACLTGEYP---EW 443
C ACLTG+YP EW
Sbjct: 487 IQENGNGLECFEKSGHCTACLTGKYPVELEW 517
>sp|P35433|PUR1_RAT AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPAT) >gi|476864|pir||A46088
amidophosphoribosyltransferase (EC 2.4.2.14) precursor
[validated] - rat >gi|466353|dbj|BAA01626.1| (D10853)
amidophosphoribosyltransferase [Rattus norvegicus]
Length = 517
Score = 322 bits (817), Expect = 5e-87
Identities = 199/511 (38%), Positives = 280/511 (53%), Gaps = 73/511 (14%)
Query: 6 GMREKCGIFGVSSE-------DAVRKTYYGLIALQHRGQEGAGISVWNG----RIRTIKG 54
G+RE+CG+FG + D GL+ LQHRGQE AGI +G + R KG
Sbjct: 7 GIREECGVFGCIASGDWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPKFRVHKG 66
Query: 55 HGLVSEVFDENSLN--LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLT 110
GLV+ VF E++L SN+ IGH RY+T+G L QP V ++A+AHNG L
Sbjct: 67 MGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELV 126
Query: 111 NFIPLRRLYEGMGIKFHSSVDTEVIGISFLNHYSQVKDE----FEAMRRVFEEVKGAYSI 166
N LR+ GI +S D+E+I Q +D+ ++ + +E AYS+
Sbjct: 127 NAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPAAYSL 186
Query: 167 LILFDGKIIAARDPVGFRPLVFG----------------EGDGYYFASEDSALRMFGLE- 209
+I+ I A RDP G RPL G E +G+ +SE + G
Sbjct: 187 VIMHRDVIYAVRDPYGNRPLCIGRLMPVSDINDKEKKSSETEGWVVSSESCSFLSIGARY 246
Query: 210 TRDVLPGEVFVIDGESYESKVLAREKH----AYCVFEYIYFARPDSTLNGINVYCARYRM 265
+V PGE+ I + + + A+C+FEY+YFARPDS VY RYR
Sbjct: 247 CHEVKPGEIVEISRHGVRTLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQMVYTVRYRC 306
Query: 266 GVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGR--G 323
G +LA E+P E D+V VP+S AALG+A + G+PY+E L KNRY+GRTFI P+ R
Sbjct: 307 GQQLAVEAPVEADLVSTVPESATPAALGYATKCGLPYVEVLCKNRYVGRTFIQPNMRLRQ 366
Query: 324 LKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPC 383
L V K + + GKR+VL+DDSIVRG T++ I+K+L+++GA+EVH+R+ASPPI++PC
Sbjct: 367 LGVAKKFGVLSDNFKGKRIVLIDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKHPC 426
Query: 384 YMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGL-----------KRAVGTKNL- 431
+MGI+IPT+ ELIA E + + +GA+S+ YLS+EGL K+ V +++
Sbjct: 427 FMGINIPTKEELIANKPEFEYLAEYLGANSVVYLSVEGLVSSVQQEIKFKKQKVKKRDIT 486
Query: 432 ----------------CMACLTGEYP---EW 443
C ACLTG+YP EW
Sbjct: 487 IQENGNGLEYFEKTGHCTACLTGQYPVDLEW 517
>pir||C81438 amidophosphoribosyltransferase (EC 2.4.2.14) Cj0196c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6967689|emb|CAB72679.1| (AL139074)
amidophosphoribosyltransferase [Campylobacter jejuni]
Length = 445
Score = 320 bits (812), Expect = 2e-86
Identities = 191/445 (42%), Positives = 277/445 (61%), Gaps = 19/445 (4%)
Query: 11 CGIFGV-SSEDAVRKTYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEVFDENSLN 68
C + GV +S++A YY L A+QHRGQE +GISV NG+ I+TIK G VS++F+ ++L
Sbjct: 2 CAVVGVINSKNASTYAYYALFAMQHRGQEASGISVSNGKNIKTIKAKGEVSQIFNPDNLK 61
Query: 69 -LASNIAIGHVRYSTSG--SLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIK 125
L IAIGH RYST+G SL++ QP+ ++A+AHNG L N +R G
Sbjct: 62 TLEGEIAIGHNRYSTAGNSSLNDAQPIAATSVLGDIALAHNGNLVNKEEVRSRLIQDGAI 121
Query: 126 FHSSVDTE-VIGISFLNHYSQVKDEF-EAMRRVFEEVKGAYSILILFDGKIIAARDPVGF 183
F +++DTE V+ + + +KD F E+++ E GAY ++ K+ RDP G
Sbjct: 122 FQTNMDTENVVHLIARSKQESLKDRFIESLK----ECIGAYCFVLASKDKLYVVRDPHGV 177
Query: 184 RPLVFG--EGDGYYFASEDSALRMFGLE-TRDVLPGE--VFVIDGESYESKVLAREKHAY 238
RPL G + GY ASE A + E RDV PGE +F + +ES L +
Sbjct: 178 RPLSLGRLKDGGYIVASETCAFDLIEAEFIRDVKPGEMLIFTQGNDKFESIELFSQTPRI 237
Query: 239 CVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHES 298
C FEYIYFARPDS + G +VY R +MG LA++ + D V+ VPDSG +AA+GFA
Sbjct: 238 CAFEYIYFARPDSIVEGKSVYEVRKKMGEALAKKFAYKADFVVPVPDSGVSAAIGFAQYL 297
Query: 299 GIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMT 356
IP +++N Y+GRTFI P+ R LKVKLKL+P+R+V+ GK +V++DDS+VRGTT
Sbjct: 298 QIPLEMAIVRNHYVGRTFIEPTQELRNLKVKLKLNPMRKVLEGKEIVVIDDSLVRGTTSK 357
Query: 357 RIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAY 416
+I+ +LR AGA ++H+ IA P I++P GID PT ELI+A ++ E++R+ + AD+L++
Sbjct: 358 KIISLLRAAGASKIHLAIACPEIKFPDTYGIDTPTFEELISANKNAEEVREYVEADTLSF 417
Query: 417 LSIEGLKRAVG-TKNLCMACLTGEY 440
LSIE L +++G + + G+Y
Sbjct: 418 LSIEELTQSIGDERKYSLISFDGDY 442
>sp|P43854|PUR1_HAEIN AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|1073836|pir||I64189
amidophosphoribosyltransferase (EC 2.4.2.14) HI1207
[similarity] - Haemophilus influenzae (strain Rd KW20)
>gi|1574137|gb|AAC22861.1| (U32800)
amidophosphoribosyltransferase (purF) [Haemophilus
influenzae Rd]
Length = 505
Score = 303 bits (767), Expect = 3e-81
Identities = 189/467 (40%), Positives = 272/467 (57%), Gaps = 38/467 (8%)
Query: 11 CGIFGVSSEDAVRKTYYG-LIALQHRGQEGAGISVWN--GRIRTIKGHGLVSEVF-DENS 66
CGI G+ S+ V ++ Y L LQHRGQ+ AGI + R R K +GLVS+VF E+
Sbjct: 2 CGIVGIVSQSPVNESIYAALTLLQHRGQDAAGIVTVDDENRFRLRKANGLVSDVFHQEHM 61
Query: 67 LNLASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLR-RLYEGMG 123
L L N +GHVRY T+GS +SE QP V Y + + HNG LTN + L+ ++++
Sbjct: 62 LRLQGNAGLGHVRYPTAGSSSVSEAQPFYVNS-PYGVTLVHNGNLTNSVELKEKVFKTAR 120
Query: 124 IKFHSSVDTEVIGISFLNHYSQV-------KDEFEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+E++ NH + +D F A+R+ ++V+GAY+ L + G ++
Sbjct: 121 RHVNTNSDSELLLNILANHLDHIPQDHLDPQDIFYAVRKTHKDVRGAYACLAMIIGHGMV 180
Query: 176 AARDPVGFRPLVFGEGD-----GYYFASEDSALRMFGLE-TRDVLPGEVFVI--DGESYE 227
A RDP G RPLV G+ + Y FASE AL + G E RD+ GE + DGE Y
Sbjct: 181 AFRDPFGIRPLVLGKREENGKTDYMFASETVALDIVGFEFVRDIAAGEAVYVTFDGELYS 240
Query: 228 SKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEG-------DVV 280
+ C+FEY+YFARPDST++G++VY AR MG +L ++ E DVV
Sbjct: 241 QQCAESAVLNPCIFEYVYFARPDSTIDGVSVYAARVHMGEKLGQKIAKEWADEIDNIDVV 300
Query: 281 IAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMP--SGRGLKVKLKLSPVREVVN 338
I VP++ AL A G PY +G +KNRY+GRTFIMP + R V+ KL+ ++
Sbjct: 301 IPVPETSTDIALQIARVLGKPYRQGFVKNRYVGRTFIMPGQAQRISSVRRKLNTIKAEFK 360
Query: 339 GKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAA 398
K V+LVDDSIVRGTT +IV+M R AGA++++ A+P IRYP GID+P+R ELIA
Sbjct: 361 DKNVLLVDDSIVRGTTSEQIVEMARSAGAKKIYFASAAPEIRYPNVYGIDMPSRDELIAY 420
Query: 399 WRSIEDIRKEIGADSLAYLSIEGLKRAVGTKNLCM-----ACLTGEY 440
R++++I + IG D L + + L +V +N + + TGEY
Sbjct: 421 GRNVDEIAELIGVDKLIFQDLTALTESVQLENPAIQGFDCSVFTGEY 467
>pir||C82618 amidophosphoribosyltransferase XF1949 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9107049|gb|AAF84751.1|AE004014_5 (AE004014)
amidophosphoribosyltransferase [Xylella fastidiosa]
Length = 485
Score = 301 bits (762), Expect = 1e-80
Identities = 193/467 (41%), Positives = 271/467 (57%), Gaps = 43/467 (9%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDENSLN 68
CGI G V +++ + Y GL LQHRGQ+ AGI+ +G R+R K +GLV +VFDE +
Sbjct: 2 CGILGIVGNQNVAGQLYDGLTVLQHRGQDAAGIATASGTRLRVQKANGLVRDVFDEQRMA 61
Query: 69 LASN-IAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPL-RRLYEGMGI 124
+ I I H RY T+GS + E QP V Y +A+AHNG L N L ++++E
Sbjct: 62 VLDGCIGIAHCRYPTAGSEGMDEAQPFYVNS-PYGIALAHNGNLINTEALHQQVFEADRR 120
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDE---------FEAMRRVFEEVKGAYSILILFDGK-I 174
++ D+EV+ LN ++ D A+ V KG Y+++ + G +
Sbjct: 121 NINTDSDSEVL----LNVFAYELDAQRMLTPEAAIRAVAGVHRRCKGGYAVVSMILGLGL 176
Query: 175 IAARDPVGFRPLVFG-----EGDGYYFASEDSALRMFG-LETRDVLPGEVFVID--GESY 226
+A RDP G RPLV G EGD Y ASE +AL + G + RDV PGE VI GE +
Sbjct: 177 VAFRDPHGIRPLVLGKRVHTEGDEYMVASESAALDILGFIRIRDVRPGEAVVITARGELF 236
Query: 227 ESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARE-----SPAEGDVVI 281
HA C+FEY+YFARPDS ++ I+V+ AR RMGV+L + + D +I
Sbjct: 237 SEVCATPTNHAPCIFEYVYFARPDSMIDNISVHKARMRMGVKLGEKILRLRPNHDIDTII 296
Query: 282 AVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGRGLKVKL---KLSPVREVVN 338
+PD+ R AAL ++ G+ Y EG +KNRY+GRTFIMP G+G +VK KL+P+
Sbjct: 297 PIPDTSRDAALEISNVLGVKYREGFVKNRYVGRTFIMP-GQGERVKSVRRKLNPIHLEFR 355
Query: 339 GKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAA 398
+ V+L+DDSIVRGTT +IV+M+RDAGAR+V++ A+PP+RYP GID+P ELIA
Sbjct: 356 NRVVLLIDDSIVRGTTSRQIVQMVRDAGARKVYLASAAPPVRYPNVYGIDMPAADELIAH 415
Query: 399 WRSIEDIRKEIGADSLAYLSIEGLKRAV-----GTKNLCMACLTGEY 440
R+ ++I+ +G D L Y +E L+ AV K +C G Y
Sbjct: 416 DRTEQEIQSLLGCDWLIYQDLEDLENAVREGNQEIKQFDSSCFNGHY 462
>pir||G83256 amidophosphoribosyltransferase PA3108 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949219|gb|AAG06496.1|AE004735_3 (AE004735)
amidophosphoribosyltransferase [Pseudomonas aeruginosa]
Length = 501
Score = 298 bits (754), Expect = 1e-79
Identities = 191/447 (42%), Positives = 263/447 (58%), Gaps = 32/447 (7%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGI-SVWNGRIRTIKGHGLVSEVFDENSLN 68
CGI G+ + V + Y L LQHRGQ+ AGI + + ++ K +GLV +VF + +
Sbjct: 2 CGIVGIVGKSNVNQALYDALTVLQHRGQDAAGIVTCHDDKLYLRKDNGLVRDVFQQRHMQ 61
Query: 69 -LASNIAIGHVRYSTSGSLS--EVQPLEVRCCGYELAIAHNGTLTNFIPL-RRLYEGMGI 124
L ++ IGHVRY T+GS S E QP V Y + +AHNG LTN L + +YE
Sbjct: 62 RLIGSVGIGHVRYPTAGSSSSAEAQPFYVNS-PYGITLAHNGNLTNVEQLAKEIYESDLR 120
Query: 125 KFHSSVDTEVIGISFLNHYSQVK--------DEFEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+EV+ ++ H V+ D F A+ V + G Y+++ + G I+
Sbjct: 121 HVNTNSDSEVL-LNVFAHELAVRNKLQPTEEDIFAAVSCVHDRCVGGYAVVAMITGHGIV 179
Query: 176 AARDPVGFRPLVFGE-----GDGYYFASEDSALRMFGLET-RDVLPGEVFVI--DGESYE 227
RDP RP+VFG+ G Y ASE AL + G RD+ PGE I +G+ Y
Sbjct: 180 GFRDPNAIRPIVFGQRHTENGVEYMIASESVALDVLGFTLIRDLAPGEAVYITEEGKLYT 239
Query: 228 SKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELA----RESPAEG-DVVIA 282
+ K+A C+FE++Y ARPDS ++GI+VY AR RMG +LA RE P DVVI
Sbjct: 240 RQCAKAPKYAPCIFEHVYLARPDSIMDGISVYKARLRMGEKLADKILRERPDHDIDVVIP 299
Query: 283 VPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMP--SGRGLKVKLKLSPVREVVNGK 340
+PD+ RTAAL A+ G+ + EG +KNRYIGRTFIMP + R V+ KL+ + GK
Sbjct: 300 IPDTSRTAALELANRLGVKFREGFVKNRYIGRTFIMPGQAARKKSVRQKLNAIELEFRGK 359
Query: 341 RVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWR 400
V+LVDDSIVRGTT +I++M R+AGA+ V+ A+P +RYP GID+P+ HELIA R
Sbjct: 360 NVMLVDDSIVRGTTCKQIIQMAREAGAKNVYFCSAAPAVRYPNVYGIDMPSAHELIAHNR 419
Query: 401 SIEDIRKEIGADSLAYLSIEGLKRAVG 427
S ED+ K IGAD L Y + L AVG
Sbjct: 420 STEDVSKLIGADWLVYQDLPDLIDAVG 446
>gb|AAF68406.1|AF237920_1 (AF237920) amidophosphoribosyltransferase [Pasteurella multocida]
Length = 504
Score = 295 bits (748), Expect = 6e-79
Identities = 184/452 (40%), Positives = 262/452 (57%), Gaps = 34/452 (7%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVWN--GRIRTIKGHGLVSEVFDE-NS 66
CGI G+ S+ V ++ Y L LQHRGQ+ AGI + R R K +GLVS+VF++ +
Sbjct: 2 CGIVGIVSQSPVNQSIYDALTLLQHRGQDAAGIVTVDDENRFRLRKANGLVSDVFEQVHM 61
Query: 67 LNLASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLR-RLYEGMG 123
L L N IGHVRY T+GS +SE QP V Y L + HNG LTN L+ +L+
Sbjct: 62 LRLQGNAGIGHVRYPTAGSSSVSEAQPFYVNS-PYGLTLVHNGNLTNSSELKEKLFRLAR 120
Query: 124 IKFHSSVDTEVIGISFLNHYSQVK-------DEFEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+E++ NH + D F A+++ ++++GAY+ + + G ++
Sbjct: 121 RHVNTNSDSELLLNILANHLDHFEKYQLDPQDVFSAVKQTHQDIRGAYACIAMIIGHGMV 180
Query: 176 AARDPVGFRPLVFGEGDG-----YYFASEDSALRMFGLE-TRDVLPGEVFVI--DGESYE 227
A RDP G RPLV G+ + Y FASE AL G E RDV PGE + +GE Y
Sbjct: 181 AFRDPNGIRPLVLGKREENGKTEYMFASESIALDTVGFEFVRDVQPGEAIYVTFEGEMYA 240
Query: 228 SKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEG------DVVI 281
+ + C+FEY+YFARPDS ++G++VY AR MG L + E DVVI
Sbjct: 241 QQCADKPTLTPCIFEYVYFARPDSCIDGVSVYAARVHMGQRLGEKIAREWADVDDIDVVI 300
Query: 282 AVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGRGLKV---KLKLSPVREVVN 338
VP++ AL A PY +G +KNRY+GRTFIMP G+ L+V + KL+ +
Sbjct: 301 PVPETSNDIALRIARVLNKPYRQGFVKNRYVGRTFIMP-GQALRVSSVRRKLNTIASEFK 359
Query: 339 GKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAA 398
K V+LVDDSIVRGTT +IV+M R AGA++++ A+P IRYP GID+PT++ELIA
Sbjct: 360 DKNVLLVDDSIVRGTTSEQIVEMARAAGAKKIYFASAAPEIRYPNVYGIDMPTKNELIAY 419
Query: 399 WRSIEDIRKEIGADSLAYLSIEGLKRAVGTKN 430
R +++I IG D L + ++ L +V +N
Sbjct: 420 GRDVDEIANLIGVDKLIFQDLDALTGSVQQEN 451
>pir||A81170 amidophosphoribosyltransferase (EC 2.4.2.14) NMB0690 [similarity] -
Neisseria meningitidis (group B strain MD58)
>gi|7225918|gb|AAF41108.1| (AE002423)
amidophosphoribosyltransferase [Neisseria meningitidis
MC58]
Length = 514
Score = 293 bits (741), Expect = 4e-78
Identities = 199/459 (43%), Positives = 261/459 (56%), Gaps = 43/459 (9%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVF-DENSL 67
CG+ G+ S + V + Y GL LQHRGQ+ AGI+ G KG G+V EVF N
Sbjct: 2 CGVLGLVSHEPVNQLLYDGLQMLQHRGQDAAGIATAEGGTFHMHKGKGMVREVFRTRNMR 61
Query: 68 NLASNIAIGHVRYSTSG---SLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
+L N I HVRY T+G S +E QP V + + +AHNG LTN LYE +
Sbjct: 62 DLTGNAGIAHVRYPTAGNAGSSAEAQPFYVSS-PFGIVLAHNGNLTN---TAELYENVCN 117
Query: 125 KF----HSSVDTEVIGISFLN------------HYSQVKDEFEAMRRVFEEVKGAYSILI 168
K ++S D+EV+ F + H + F A+ +V V+GAY ++
Sbjct: 118 KHLRHVNTSSDSEVLLNVFAHELRREVSKNADPHRLNADNIFNAVAQVHRLVRGAYGVIA 177
Query: 169 LFDGK-IIAARDPVGFRPLVFG-----EG-DGYYFASEDSALRMFGLET-RDVLPGE-VF 219
+ G ++A RDP G RPLV G EG Y ASE A + RD+ PGE VF
Sbjct: 178 MIAGYGMLAFRDPYGIRPLVLGSQTDSEGRKSYAVASESVAFNALTYDLERDIRPGEAVF 237
Query: 220 V-IDGESYESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELA----RESP 274
V DG + R K + C+FEY+YFARPDS ++G++VY +R MGV LA RE P
Sbjct: 238 VGFDGTMIARQCSDRAKLSPCLFEYVYFARPDSVIDGVSVYQSRLDMGVSLAEKIKRELP 297
Query: 275 AEG-DVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMP--SGRGLKVKLKLS 331
+G DVV+ +PD+ R +A+ A PY EGLIKNRYIGRTFIMP + R V+ KLS
Sbjct: 298 VDGIDVVMPIPDTSRPSAMELAVHLDKPYREGLIKNRYIGRTFIMPGQATRKKSVRQKLS 357
Query: 332 PVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPT 391
P+ GK V+LVDDSIVRGTT IV+M+R AGAR+V++ A+P +RYP GID+PT
Sbjct: 358 PMETEFAGKSVLLVDDSIVRGTTSREIVEMVRAAGARKVYIASAAPEVRYPNVYGIDMPT 417
Query: 392 RHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRAVGTKN 430
R ELIA RS +I EIGAD + + + L+ V N
Sbjct: 418 REELIANGRSAAEIAAEIGADGIVFQDLGDLEAVVKALN 456
>pir||G81935 amidophosphoribosyltransferase (EC 2.4.2.14) NMA0892 [similarity] -
Neisseria meningitidis (group A strain Z2491)
>gi|7379607|emb|CAB84172.1| (AL162754) putative
amidophosphoribosyltransferase [Neisseria meningitidis
Z2491]
Length = 514
Score = 289 bits (733), Expect = 3e-77
Identities = 198/459 (43%), Positives = 259/459 (56%), Gaps = 43/459 (9%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVF-DENSL 67
CG+ G+ S + V + Y GL LQHRGQ+ AGI+ G KG G+V EVF N
Sbjct: 2 CGVLGLVSHEPVNQLLYDGLQMLQHRGQDAAGIATAEGGTFHMHKGKGMVREVFRTRNMR 61
Query: 68 NLASNIAIGHVRYSTSG---SLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
+L N I HVRY T+G S +E QP V + + +AHNG LTN LYE +
Sbjct: 62 DLVGNAGIAHVRYPTAGNAGSSAEAQPFYVSS-PFGIVLAHNGNLTN---TAELYENVCN 117
Query: 125 KF----HSSVDTEVIGISFLN------------HYSQVKDEFEAMRRVFEEVKGAYSILI 168
K ++S D+EV+ F + H + F A+ V V GAY ++
Sbjct: 118 KHLRHVNTSSDSEVLLNVFAHELRREVSKNADPHRLNADNIFNAVAEVHRLVHGAYGVVA 177
Query: 169 LFDGK-IIAARDPVGFRPLVFG-----EG-DGYYFASEDSALRMFGLET-RDVLPGE-VF 219
+ G ++A RDP G RPLV G EG Y ASE A + RD+ PGE VF
Sbjct: 178 MIAGYGMLAFRDPYGIRPLVLGSQTDSEGRKSYAVASESVAFNALAYDLERDIRPGEAVF 237
Query: 220 V-IDGESYESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELA----RESP 274
V DG + + K + C+FEY+YFARPDS ++G++VY +R MGV LA RE P
Sbjct: 238 VGFDGTIIARQCSDKAKLSPCLFEYVYFARPDSVIDGVSVYQSRLDMGVSLAEKIKRELP 297
Query: 275 AEG-DVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMP--SGRGLKVKLKLS 331
+G DVV+ +PD+ R +A+ A PY EGLIKNRYIGRTFIMP + R V+ KLS
Sbjct: 298 VDGIDVVMPIPDTSRPSAMELAVHLKKPYREGLIKNRYIGRTFIMPGQATRKKSVRQKLS 357
Query: 332 PVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPT 391
P+ GK V+LVDDSIVRGTT IV+M+R AGAR+V++ A+P +RYP GID+PT
Sbjct: 358 PMETEFAGKSVLLVDDSIVRGTTSREIVEMVRAAGARKVYIASAAPEVRYPNVYGIDMPT 417
Query: 392 RHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRAVGTKN 430
R ELIA RS +I EIGAD + + + L+ V N
Sbjct: 418 REELIANGRSAAEIAAEIGADGIVFQDLGDLEAVVKALN 456
>pir||T24422 amidophosphoribosyltransferase (EC 2.4.2.14) [similarity] -
Caenorhabditis elegans >gi|3879338|emb|CAA84723.1|
(Z35663) Amidophosphoribosyltransferase (glutamine
phosphoribosylpyrophosphate amidotransferase), contains
similarity to Pfam domain: PF00156 (Phosphoribosyl
transferase domain), Score=15.0, E-value=0.0005, N=1;
PF00310 (Glutamine amidotransferases cla>
Length = 480
Score = 288 bits (730), Expect = 7e-77
Identities = 182/474 (38%), Positives = 267/474 (55%), Gaps = 43/474 (9%)
Query: 11 CGIFGVSS----EDAVRKTYYGLIALQHRGQEGAGI----SVWNGRIRTIKGHGLVSEVF 62
CGIFG+ + E GL ALQHRG E G+ + + IKGHGLV +V
Sbjct: 2 CGIFGIVAAGNYEHLNVLAANGLAALQHRGTESTGLVGSDGITRDHVEIIKGHGLVRDVI 61
Query: 63 DENSLNLAS--NIAIGHVRYSTSGS----LSEVQPLEVRCCGYELAIAHNGTLTNFIPLR 116
E++++ + +I IGH RYST+G ++ VQP V +AIAHNG L + R
Sbjct: 62 TEDNISRMNGQSIIIGHNRYSTAGKKKSGINCVQPFVVYTAMGTVAIAHNGELVDAKQKR 121
Query: 117 R--LYEGMGIKFHSSVD------TEVIGISFLNHYSQ-VKDEFEAMRRVFEEVKGAYSIL 167
+ L+EG+G+ + + + I ++ Y Q + D + + +YS+L
Sbjct: 122 KEVLHEGVGLSTDTDSELIAQMIAKAIALNVKCKYGQEMGDITRELAVTMSALNMSYSLL 181
Query: 168 ILFDGKIIAARDPVGFRPLVFG-------EGDGYYFASEDSALRMFGLETRDVLPGEVFV 220
++ ++ A RDP G RPL G + + +SE A +V PGE+
Sbjct: 182 VMTFDRLYAIRDPFGNRPLCVGTVYSKNGNPEAFIASSESCAFPANAKLDFEVRPGEIVE 241
Query: 221 IDGESYES--KVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGD 278
+ +S ++ A C+FEY+YFAR DS + G V R G +A E E D
Sbjct: 242 LSTGGIKSVWQMKPNTPLAMCIFEYVYFARNDSEIEGQQVQTVREECGKTMALEDDLEAD 301
Query: 279 VVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREV 336
+V VPDS +AA+G+A +SGI Y L +N Y+GR+FI P+ R +K+K +++
Sbjct: 302 IVGNVPDSSLSAAIGYASQSGITYEPVLHRNSYVGRSFIEPNDEMRQNAIKMKFGVLKKK 361
Query: 337 VNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELI 396
++G+R+VLVDDSIVRG TM +VKMLRDAGA+EVH+RIASPP+++PC+MGI+IPT ELI
Sbjct: 362 IHGQRIVLVDDSIVRGNTMRTLVKMLRDAGAKEVHLRIASPPVKFPCFMGINIPTTKELI 421
Query: 397 AAWRSIEDIRKEIGADSLAYLSIEGLKRAVG---------TKNLCMACLTGEYP 441
AA ++I +I + +GADS+ YLS++GL +V + C ACLTG+YP
Sbjct: 422 AAEKTIPEICQFVGADSVRYLSVDGLVSSVQKGIERAANFSPGHCTACLTGKYP 475
>pir||F82253 amidophosphoribosyltransferase VC1004 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9655467|gb|AAF94165.1|
(AE004182) amidophosphoribosyltransferase [Vibrio
cholerae]
Length = 504
Score = 282 bits (713), Expect = 7e-75
Identities = 182/448 (40%), Positives = 255/448 (56%), Gaps = 29/448 (6%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGI-SVWNGRIRTIKGHGLVSEVFDENSLN 68
CGI G+ V ++ Y L LQHRGQ+ AGI ++ + R R K +GLV +VF+ +
Sbjct: 2 CGIVGIVGTTPVNQSIYDALTVLQHRGQDAAGICTIESNRFRLRKANGLVRDVFEAKHMQ 61
Query: 69 -LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLR-RLYEGMGI 124
L N+ IGHVRY T+GS SE QP V + + +AHNG LTN +R +L+E
Sbjct: 62 RLQGNVGIGHVRYPTAGSSSASEAQPFYVNS-PFGITLAHNGNLTNANQVRQKLFEKDRR 120
Query: 125 KFHSSVDTEVIGISFLNHYSQVK------DEFEAMRRVFEEVKGAYSILILFDGK-IIAA 177
+++ D+EV+ + VK D F A+ V ++GAY++ + G +IA
Sbjct: 121 HVNTTSDSEVLLNVLAHEIDTVKGNVTADDVFRAISNVHRTIRGAYAVAAMIIGHGMIAF 180
Query: 178 RDPVGFRPLVFGEGD-----GYYFASEDSALRMFGLE-TRDVLPGEVF--VIDGESYESK 229
RDP G RPL G+ + Y ASE AL G + RDV PGE DGE Y +
Sbjct: 181 RDPHGIRPLCLGKREVNGQLEYMVASESVALDAVGFDFVRDVAPGEAIYATFDGELYTKQ 240
Query: 230 VLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARE-----SPAEGDVVIAVP 284
C+FE++YFARPDS ++ I+VY AR MG L S + DVVI +P
Sbjct: 241 CADNPALNPCIFEFVYFARPDSFIDKISVYSARVEMGKRLGERIKNDYSDLDIDVVIPIP 300
Query: 285 DSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGRGLK--VKLKLSPVREVVNGKRV 342
++ AL A PY +G +KNRY+GRTFIMP + K V+ KL+ +R K V
Sbjct: 301 ETSCDIALQIAQAIDKPYRQGFVKNRYVGRTFIMPGQQQRKKSVRRKLNAIRSEFKDKNV 360
Query: 343 VLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSI 402
+LVDDSIVRGTT +I++M RD+GA++V++ A+P IR+P GID+P+ +ELIA R
Sbjct: 361 LLVDDSIVRGTTSEQIIEMARDSGAKKVYIVSAAPEIRFPNVYGIDMPSANELIAHGRDN 420
Query: 403 EDIRKEIGADSLAYLSIEGLKRAVGTKN 430
+ I K+IGAD+L + ++E L AV N
Sbjct: 421 DAICKQIGADALIFQTLEDLVEAVRCGN 448
>sp|P00496|PUR1_ECOLI AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|7427943|pir||XQEC
amidophosphoribosyltransferase (EC 2.4.2.14) [validated]
- Escherichia coli >gi|1788651|gb|AAC75372.1| (AE000320)
amidophosphoribosyltransferase = PRPP amidotransferase
[Escherichia coli K12]
Length = 505
Score = 277 bits (701), Expect = 2e-73
Identities = 184/451 (40%), Positives = 255/451 (55%), Gaps = 32/451 (7%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVW--NGRIRTIKGHGLVSEVFDENSL 67
CGI G++ V ++ Y L LQHRGQ+ AGI N R K +GLVS+VF+ +
Sbjct: 2 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANGLVSDVFEARHM 61
Query: 68 N-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRR-LYEGMG 123
L N+ IGHVRY T+GS SE QP V Y + +AHNG LTN LR+ L+E
Sbjct: 62 QRLQGNMGIGHVRYPTAGSSSASEAQPFYVNS-PYGITLAHNGNLTNAHELRKKLFEEKR 120
Query: 124 IKFHSSVDTEVIGISFLN------HYSQVKDE-FEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+E++ F + HY D F A+ ++GAY+ + + G ++
Sbjct: 121 RHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMV 180
Query: 176 AARDPVGFRPLVFGEGD------GYYFASEDSALRMFGLE-TRDVLPGEVFVI--DGESY 226
A RDP G RPLV G+ D Y ASE AL G + RDV PGE I +G+ +
Sbjct: 181 AFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLGFDFLRDVAPGEAIYITEEGQLF 240
Query: 227 ESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEG-----DVVI 281
+ C+FEY+YFARPDS ++ I+VY AR MG +L + E DVVI
Sbjct: 241 TRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARVNMGTKLGEKIAREWEDLDIDVVI 300
Query: 282 AVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNG 339
+P++ AL A G PY +G +KNRY+GRTFIMP R V+ KL+ R
Sbjct: 301 PIPETSCDIALEIARILGKPYRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRD 360
Query: 340 KRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAW 399
K V+LVDDSIVRGTT +I++M R+AGA++V++ A+P IR+P GID+P+ ELIA
Sbjct: 361 KNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHG 420
Query: 400 RSIEDIRKEIGADSLAYLSIEGLKRAVGTKN 430
R +++IR+ IGAD L + + L AV +N
Sbjct: 421 REVDEIRQIIGADGLIFQDLNDLIDAVRAEN 451
>pdb|1ECF|B Chain B, Escherichia Coli Glutamine Phosphoribosylpyrophosphate
(Prpp) Amidotransferase >gi|1943560|pdb|1ECG|B Chain B,
Don Inactivated Escherichia Coli Glutamine
Phosphoribosylpyrophosphate (Prpp) Amidotransferase
>gi|3114340|pdb|1ECC|A Chain A, Escherichia Coli
Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase Complexed With Mn-Cprpp And
5-Oxo-Norleucine >gi|3114341|pdb|1ECC|B Chain B,
Escherichia Coli Glutamine Phosphoribosylpyrophosphate
(Prpp) Amidotransferase Complexed With Mn-Cprpp And
5-Oxo-Norleucine >gi|3114342|pdb|1ECJ|A Chain A,
Escherichia Coli Glutamine Phosphoribosylpyrophosphate
(Prpp) Amidotransferase Complexed With 2 Amp Per
Tetramer >gi|3114343|pdb|1ECJ|B Chain B, Escherichia
Coli Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase Complexed With 2 Amp Per Tetramer
>gi|3114344|pdb|1ECJ|C Chain C, Escherichia Coli
Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase Complexed With 2 Amp Per Tetramer
>gi|3114345|pdb|1ECJ|D Chain D, Escherichia Coli
Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase Complexed With 2 Amp Per Tetramer
>gi|1943557|pdb|1ECF|A Chain A, Escherichia Coli
Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase >gi|1943559|pdb|1ECG|A Chain A, Don
Inactivated Escherichia Coli Glutamine
Phosphoribosylpyrophosphate (Prpp) Amidotransferase
>gi|3114338|pdb|1ECB|C Chain C, Escherichia Coli
Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase Complexed With 2 Gmp, 1 Mg Per Subunit
>gi|3114336|pdb|1ECB|A Chain A, Escherichia Coli
Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase Complexed With 2 Gmp, 1 Mg Per Subunit
>gi|3114339|pdb|1ECB|D Chain D, Escherichia Coli
Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase Complexed With 2 Gmp, 1 Mg Per Subunit
>gi|3114337|pdb|1ECB|B Chain B, Escherichia Coli
Glutamine Phosphoribosylpyrophosphate (Prpp)
Amidotransferase Complexed With 2 Gmp, 1 Mg Per Subunit
>gi|1799693|dbj|BAA16158.1| (D90862)
AMIDOPHOSPHORIBOSYLTRANSFERASE (EC 2.4.2.14) (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE).
[Escherichia coli]
Length = 504
Score = 277 bits (701), Expect = 2e-73
Identities = 184/451 (40%), Positives = 255/451 (55%), Gaps = 32/451 (7%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVW--NGRIRTIKGHGLVSEVFDENSL 67
CGI G++ V ++ Y L LQHRGQ+ AGI N R K +GLVS+VF+ +
Sbjct: 1 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANGLVSDVFEARHM 60
Query: 68 N-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRR-LYEGMG 123
L N+ IGHVRY T+GS SE QP V Y + +AHNG LTN LR+ L+E
Sbjct: 61 QRLQGNMGIGHVRYPTAGSSSASEAQPFYVNS-PYGITLAHNGNLTNAHELRKKLFEEKR 119
Query: 124 IKFHSSVDTEVIGISFLN------HYSQVKDE-FEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+E++ F + HY D F A+ ++GAY+ + + G ++
Sbjct: 120 RHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMV 179
Query: 176 AARDPVGFRPLVFGEGD------GYYFASEDSALRMFGLE-TRDVLPGEVFVI--DGESY 226
A RDP G RPLV G+ D Y ASE AL G + RDV PGE I +G+ +
Sbjct: 180 AFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLGFDFLRDVAPGEAIYITEEGQLF 239
Query: 227 ESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEG-----DVVI 281
+ C+FEY+YFARPDS ++ I+VY AR MG +L + E DVVI
Sbjct: 240 TRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARVNMGTKLGEKIAREWEDLDIDVVI 299
Query: 282 AVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNG 339
+P++ AL A G PY +G +KNRY+GRTFIMP R V+ KL+ R
Sbjct: 300 PIPETSCDIALEIARILGKPYRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRD 359
Query: 340 KRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAW 399
K V+LVDDSIVRGTT +I++M R+AGA++V++ A+P IR+P GID+P+ ELIA
Sbjct: 360 KNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHG 419
Query: 400 RSIEDIRKEIGADSLAYLSIEGLKRAVGTKN 430
R +++IR+ IGAD L + + L AV +N
Sbjct: 420 REVDEIRQIIGADGLIFQDLNDLIDAVRAEN 450
>emb|CAA30971.1| (X12423) amidophosphoribosyltransferase [Escherichia coli]
Length = 505
Score = 275 bits (696), Expect = 7e-73
Identities = 183/451 (40%), Positives = 254/451 (55%), Gaps = 32/451 (7%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVW--NGRIRTIKGHGLVSEVFDENSL 67
CGI G++ V ++ Y L LQHRGQ+ AGI N R K +GLVS+VF+ +
Sbjct: 2 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANGLVSDVFEARHM 61
Query: 68 N-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRR-LYEGMG 123
L N+ IGHVRY T+GS SE QP V Y + +AHNG LTN LR+ L+E
Sbjct: 62 QRLQGNMGIGHVRYPTAGSSSASEAQPFYVNS-PYGITLAHNGNLTNAHELRKKLFEEKR 120
Query: 124 IKFHSSVDTEVIGISFLN------HYSQVKDE-FEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+E++ F + HY D F A+ ++GAY+ + + G ++
Sbjct: 121 RHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMV 180
Query: 176 AARDPVGFRPLVFGEGD------GYYFASEDSALRMFGLE-TRDVLPGEVFVI--DGESY 226
A RDP G RPLV G+ D Y ASE AL G + RDV PGE I +G+ +
Sbjct: 181 AFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLGFDFLRDVAPGEAIYITEEGQLF 240
Query: 227 ESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEG-----DVVI 281
+ C+FEY+YFARPDS ++ I+VY AR MG +L + E DVVI
Sbjct: 241 TRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARVNMGTKLGEKIAREWEDLDIDVVI 300
Query: 282 AVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNG 339
+P++ AL A G PY +G +KNRY+GRTFIMP R V+ KL+ R
Sbjct: 301 PIPETSCDIALEIARILGKPYRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRD 360
Query: 340 KRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAW 399
K V+LVDDSIVRGTT +I++M R+ GA++V++ A+P IR+P GID+P+ ELIA
Sbjct: 361 KNVLLVDDSIVRGTTSEQIIEMARERGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHG 420
Query: 400 RSIEDIRKEIGADSLAYLSIEGLKRAVGTKN 430
R +++IR+ IGAD L + + L AV +N
Sbjct: 421 REVDEIRQIIGADGLIFQDLNDLIDAVRAEN 451
>sp|P41390|PUR1_SCHPO AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
>gi|629904|pir||S43526 amidophosphoribosyltransferase
(EC 2.4.2.14) - fission yeast (Schizosaccharomyces
pombe) >gi|410512|emb|CAA51034.1| (X72293) PRPP
amidotransferase [Schizosaccharomyces pombe]
>gi|2330811|emb|CAB11280.1| (Z98602)
amidophosphoribosyltransferase [Schizosaccharomyces
pombe]
Length = 533
Score = 264 bits (668), Expect = 1e-69
Identities = 182/483 (37%), Positives = 255/483 (52%), Gaps = 57/483 (11%)
Query: 11 CGIFGVSSED----AVRKTYYGLIALQHRGQEGAGISVWN--GRIRTIKGHGLVSEVFDE 64
CGI + D A + Y GL +LQHRGQ+ AGI GR+ KG G+V++VF +
Sbjct: 2 CGILALMLADPHQQACPEIYEGLYSLQHRGQDAAGIVTAGNKGRLYQCKGSGMVADVFSQ 61
Query: 65 NSLN-LASNIAIGHVRYSTSGSL--SEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
+ L L ++ IGH+RY T+GS SE QP V Y L + HNG L N LRR +
Sbjct: 62 HQLRQLVGSMGIGHLRYPTAGSCAHSEAQPFYVNS-PYGLVLGHNGNLINGPELRRFLD- 119
Query: 122 MGIKFHSSVDTEVIGISFLNHYS-----------QVKDEFEAMRRVFEEVKGAYSILILF 170
+ H V+T LN ++ D FEA+R V++ V G Y+ + +
Sbjct: 120 --TEAHRHVNTGSDSELLLNIFAYELQRLDKFRINENDIFEALRNVYDRVNGGYACVAMI 177
Query: 171 DGK-IIAARDPVGFRPLVFGE-----GDGYYFASEDSALRMFGLET-RDVLPGEVFVIDG 223
G ++ RDP G RPLV GE G Y ASE L FG T RD+ PGE I
Sbjct: 178 AGLGVLGFRDPNGIRPLVIGERDTPEGKDYMLASESVVLTQFGYRTFRDIRPGECVFIRR 237
Query: 224 ESYES-------------KVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELA 270
+ E ++L + +FEY+YFARPDS ++G++VY +R MG +LA
Sbjct: 238 SNREDILAGFRGPRLFSRQILPCLRFTPDIFEYVYFARPDSVIDGLSVYQSRLNMGEKLA 297
Query: 271 R--------ESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG- 321
+ + D VI VPDS RT+AL A + +PY+E IKNRYIGRTFIMP
Sbjct: 298 HTIMKRFGPDYMEKIDAVIPVPDSARTSALALAQTAQLPYVEAFIKNRYIGRTFIMPGQQ 357
Query: 322 -RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIR 380
R V+ KL+ + K V++VDDSIVRGTT IV+M R++GA+ V++ +P I
Sbjct: 358 IRRKSVRRKLNVQPQEFFDKNVLIVDDSIVRGTTSREIVQMARESGAKNVYLASCAPMIT 417
Query: 381 YPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRAVGTKNLC---MACLT 437
+P GID+ +LIA ++ +++ + I AD + Y ++E L + T L + T
Sbjct: 418 HPHVYGIDLADCKDLIAYGKTEDEVAEAISADGVIYQTLEDLLDSCRTAELTEFEVGLFT 477
Query: 438 GEY 440
GEY
Sbjct: 478 GEY 480
>emb|CAA23613.1| (V00322) reading frame purF [Escherichia coli]
>gi|147416|gb|AAA24452.1| (J01666)
amidophosphoribosyltransferase (EC 2.4.2.14)
[Escherichia coli]
Length = 504
Score = 259 bits (654), Expect = 6e-68
Identities = 173/450 (38%), Positives = 252/450 (55%), Gaps = 31/450 (6%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVW--NGRIRTIKGHGLVSEVFDENSL 67
CGI G++ V ++ Y L LQHRGQ+ AGI N R++K + LVS+VF+ +
Sbjct: 2 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRSLKANALVSDVFEARHM 61
Query: 68 N-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRR-LYEGMG 123
L N+ IGHVRY T+GS SE QP V Y + +AHNG LTN LR+ L+E
Sbjct: 62 QRLQGNMGIGHVRYPTAGSSSASEAQPFYVNS-PYGITLAHNGNLTNAHELRKKLFEEKR 120
Query: 124 IKFHSSVDTEVIGISFLN------HYSQVKDE-FEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+E++ F + HY D F A+ ++GAY+ + + G ++
Sbjct: 121 RHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMV 180
Query: 176 AARDPVGFRPLVFGEGD------GYYFASED-SALRMFGLETRDVLPGEVFVID-GESYE 227
A RDP G RPLV G+ D Y ASE ++R + +++ + G+ +
Sbjct: 181 AFRDPNGIRPLVLGKRDIDENRTEYMVASESVGSIRWALISCVTSRRARIYITEEGQLFT 240
Query: 228 SKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEG-----DVVIA 282
+ C+FEY+YFARPDS ++ I+VY AR MG ++ + E DVVI
Sbjct: 241 RQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARANMGTKVGEKIAREWEDLDIDVVIP 300
Query: 283 VPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGK 340
+P++ AL A G PY +G +KNRY+GRTFIMP R V+ KL+ R K
Sbjct: 301 IPETSCDIALEIARILGKPYRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRDK 360
Query: 341 RVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWR 400
V+LVDDSIVRGTT +I++M R+AGA++V++ A+P IR+P GID+P+ ELIA R
Sbjct: 361 NVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHGR 420
Query: 401 SIEDIRKEIGADSLAYLSIEGLKRAVGTKN 430
+++IR+ IGAD L + + L AV +N
Sbjct: 421 EVDEIRQIIGADGLIFQDLNDLIDAVRAEN 450
>gi|6323958 phosphoribosylpyrophosphate amidotransferase; Ade4p [Saccharomyces
cerevisiae] >gi|1346913|sp|P04046|PUR1_YEAST
AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
>gi|1076995|pir||S53970 amidophosphoribosyltransferase
(EC 2.4.2.14) - yeast (Saccharomyces cerevisiae)
>gi|798942|emb|CAA89133.1| (Z49212) Ade4p [Saccharomyces
cerevisiae]
Length = 510
Score = 259 bits (654), Expect = 6e-68
Identities = 174/452 (38%), Positives = 244/452 (53%), Gaps = 44/452 (9%)
Query: 11 CGIFGV----SSEDAVRKTYYGLIALQHRGQEGAGISVWN--GRIRTIKGHGLVSEVFDE 64
CGI G+ + + G I LQHRGQ+ AGI+ GRI KG+G+ +VF +
Sbjct: 2 CGILGIVLANQTTPVAPELCDGCIFLQHRGQDAAGIATCGSRGRIYQCKGNGMARDVFTQ 61
Query: 65 NSLN-LASNIAIGHVRYSTSGSL--SEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEG 121
++ LA ++ I H+RY T+GS SE QP V Y + +AHNG L N L+R
Sbjct: 62 QRVSGLAGSMGIAHLRYPTAGSSANSEAQPFYVNS-PYGINLAHNGNLVNTASLKRY--- 117
Query: 122 MGIKFHSSVDTEVIGISFLNHYSQV-----------KDEFEAMRRVFEEVKGAYSILILF 170
M H ++T+ LN ++ +D F A+ V+ +G Y+ + L
Sbjct: 118 MDEDVHRHINTDSDSELLLNIFAAELEKHNKYRVNNEDVFHALEGVYRLCRGGYACVGLL 177
Query: 171 DG-KIIAARDPVGFRPLVFGEGDG------YYFASEDSALRMFGL-ETRDVLPGEVFVID 222
G + RDP G RPL+FGE + Y ASE + + RD+ PGE +I
Sbjct: 178 AGFALFGFRDPNGIRPLLFGERENPDGTKDYMLASESVVFKAHNFTKYRDLKPGEAVIIP 237
Query: 223 -----GESYESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARE----- 272
GE +V+ + +FEY+YFARPDS L+GI+VY R MG +LA
Sbjct: 238 KNCSKGEPEFKQVVPINSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGSKLAENILKQL 297
Query: 273 SPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGRGL--KVKLKL 330
P + DVVI VPD+ RT AL A+ G PY EG +KNRY+GRTFIMP+ R V+ KL
Sbjct: 298 KPEDIDVVIPVPDTARTCALECANVLGKPYREGFVKNRYVGRTFIMPNQRERVSSVRRKL 357
Query: 331 SPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIP 390
+P+ GK+V++VDDSIVRGTT IV M +++GA +V+ A+P IRY GID+
Sbjct: 358 NPMESEFKGKKVLIVDDSIVRGTTSKEIVNMAKESGATKVYFASAAPAIRYNHIYGIDLT 417
Query: 391 TRHELIAAWRSIEDIRKEIGADSLAYLSIEGL 422
LIA R+ E++ + IG + + Y S+E L
Sbjct: 418 DTKNLIAYNRTDEEVAEVIGCERVIYQSLEDL 449
>sp|Q12698|PUR1_SACKL AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
>gi|987516|gb|AAA75450.1| (U32992) glutamine
phosphoribosylpyrophosphate amidotransferase
[Saccharomyces kluyveri]
Length = 510
Score = 258 bits (652), Expect = 1e-67
Identities = 167/449 (37%), Positives = 254/449 (56%), Gaps = 38/449 (8%)
Query: 11 CGIFGVSSED----AVRKTYYGLIALQHRGQEGAGISVWN--GRIRTIKGHGLVSEVFDE 64
CGI G++ D + + G + LQHRGQ+ AG++ GR+ KG+G+ +VF +
Sbjct: 2 CGILGIALADQSSVVAPELFDGSLFLQHRGQDAAGMATCGERGRLYQCKGNGMARDVFTQ 61
Query: 65 NSLN-LASNIAIGHVRYSTSGSL--SEVQPLEVRCCGYELAIAHNGTLTNFIPLRR-LYE 120
+ ++ L ++ I H+RY T+GS SE QP V Y + ++HNGTL N + LR L E
Sbjct: 62 HRMSGLVGSMGIAHLRYPTAGSCANSEAQPFYVNS-PYGICLSHNGTLVNTLSLRSYLDE 120
Query: 121 GMGIKFHSSVDTEVIGISFL------NHYSQVKDE-FEAMRRVFEEVKGAYSILILFDG- 172
+ ++ D+E++ F N Y D+ F A+ V+ + +G Y+ + + G
Sbjct: 121 VVHRHINTDSDSELLLNVFAAELERHNKYRVNNDDIFHALEGVYRQCRGGYACVGMLAGY 180
Query: 173 KIIAARDPVGFRPLVFGEG---DG---YYFASEDSALRMFGLET-RDVLPGEVFVIDGES 225
+ RDP G RPL+FGE DG Y ASE L+ RD+ PGE +I +
Sbjct: 181 SLFGFRDPNGIRPLLFGERVNPDGTKDYMLASESVVLKAHNFNKFRDLKPGEAVIIPKDC 240
Query: 226 YESK-----VLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARE-----SPA 275
+ + V+ + +FEY+YFARPDS L+GI+VY R +MG++LA P
Sbjct: 241 NKQEPEFRQVVPTNSYRPDLFEYVYFARPDSVLDGISVYHTRLQMGIKLAENVKKVVDPD 300
Query: 276 EGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPV 333
E DVV++VPD+ RT AL A+ PY E +KNRY+GRTFIMP+ R V+ KL+P+
Sbjct: 301 EIDVVVSVPDTARTCALQCANHLNKPYREAFVKNRYVGRTFIMPNQKERVSSVRRKLNPM 360
Query: 334 REVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRH 393
KRV++VDDSIVRGTT I+ M +++GA +V+ A+P IR+ GID+
Sbjct: 361 DFEFKDKRVLIVDDSIVRGTTSKEIINMAKESGATKVYFASAAPAIRFNHIYGIDLADTK 420
Query: 394 ELIAAWRSIEDIRKEIGADSLAYLSIEGL 422
+L+A R+ +++ +E+G + + Y S+E L
Sbjct: 421 QLVAYNRTTDEVAQELGCEKVIYQSLEDL 449
>gb|AAA24453.1| (M26893) amidophosphoribosyltransferase (EC 2.4.2.14) [Escherichia
coli]
Length = 504
Score = 257 bits (650), Expect = 2e-67
Identities = 172/450 (38%), Positives = 252/450 (55%), Gaps = 31/450 (6%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVW--NGRIRTIKGHGLVSEVFDENSL 67
CGI G++ V ++ Y L LQHRGQ+ AGI N R++K + LVS+VF+ +
Sbjct: 2 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRSLKANALVSDVFEARHM 61
Query: 68 N-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRR-LYEGMG 123
L N+ IGHVRY T+GS SE QP V Y + +AHNG LTN LR+ L+E
Sbjct: 62 QRLQGNMGIGHVRYPTAGSSSASEAQPFYVNS-PYGITLAHNGNLTNAHELRKKLFEEKR 120
Query: 124 IKFHSSVDTEVIGISFLN------HYSQVKDE-FEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+E++ F + HY D F A+ ++GAY+ + + G ++
Sbjct: 121 RHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMV 180
Query: 176 AARDPVGFRPLVFGEGD------GYYFASED-SALRMFGLETRDVLPGEVFVID-GESYE 227
A RDP G RPLV G+ D Y ASE ++R + +++ + G+ +
Sbjct: 181 AFRDPNGIRPLVLGKRDIDENRTEYMVASESVGSIRWALISCVTSRRARIYITEEGQLFT 240
Query: 228 SKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEG-----DVVIA 282
+ C+FEY+YFARPDS ++ I+VY AR MG ++ + E DVVI
Sbjct: 241 RQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARANMGTKVGEKIAREWEDLDIDVVIP 300
Query: 283 VPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGK 340
+P++ AL A G PY +G +KNRY+GRTFI+P R V+ KL+ R K
Sbjct: 301 IPETSCDIALEIARILGKPYRQGFVKNRYVGRTFIIPGQQLRRKSVRRKLNANRAEFRDK 360
Query: 341 RVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWR 400
V+LVDDSIVRGTT +I++M R+AGA++V++ A+P IR+P GID+P+ ELIA R
Sbjct: 361 NVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHGR 420
Query: 401 SIEDIRKEIGADSLAYLSIEGLKRAVGTKN 430
+++IR+ IGAD L + + L AV +N
Sbjct: 421 EVDEIRQIIGADGLIFQDLNDLIDAVRAEN 450
>gb|AAA34403.1| (K02203) amidophosphoribosyltransferase [Saccharomyces cerevisiae]
>gi|171011|gb|AAA34404.1| (M74309)
amidophosphoribosyltransferase [Saccharomyces
cerevisiae]
Length = 510
Score = 252 bits (637), Expect = 6e-66
Identities = 171/452 (37%), Positives = 242/452 (52%), Gaps = 44/452 (9%)
Query: 11 CGIFGV----SSEDAVRKTYYGLIALQHRGQEGAGISVWN--GRIRTIKGHGLVSEVFDE 64
CGI G+ + + G I LQHRGQ+ AGI+ GR+ KG+G+ +VF +
Sbjct: 2 CGILGIVLANQTTPVAPELCDGCIFLQHRGQDAAGIATCGSRGRVCQCKGNGMARDVFTQ 61
Query: 65 NSLNLASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGM 122
LA ++ I H+RY T G + E QP V Y + +AHNG L N L+R M
Sbjct: 62 RVSGLAGSMGIAHLRYPTPGLRLILEAQPFYVNS-PYGINLAHNGNLVNTASLKRY---M 117
Query: 123 GIKFHSSVDTEVIGISFLNHYS---------QVKDE---FEAMRRVFEEVKGAYSILILF 170
H ++T+ LN ++ +V +E A+ V+ +G Y+ + L
Sbjct: 118 DEDVHRHINTDSDSELLLNIFAAELEKHNKYRVNNEDGFSNALEGVYRLCRGGYACVGLL 177
Query: 171 DG-KIIAARDPVGFRPLVFGEGDG------YYFASEDSALRMFGL-ETRDVLPGEVFVID 222
G + RDP G RPL+FGE + Y ASE + + RD+ PGE +I
Sbjct: 178 AGFALFGFRDPNGIRPLLFGERENPDGTKDYMLASESVVFKAHNFTKYRDLKPGEAGIIP 237
Query: 223 -----GESYESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARE----- 272
GE +V+ + +FEY+YFARPDS L+GI+VY R MG +LA+
Sbjct: 238 KNCSKGEPEFKQVVPINSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGSKLAQNILKQL 297
Query: 273 SPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSGRGL--KVKLKL 330
P + DVVI VPD+ RT AL A+ G PY EG +KNRY+GRTFIMP+ R V+ KL
Sbjct: 298 KPEDIDVVIPVPDTARTCALECANVLGKPYREGFVKNRYVGRTFIMPNQRERVSSVRRKL 357
Query: 331 SPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGIDIP 390
+P+ GK+V++VDDSIVRGTT IV M +++GA +V+ A+P IRY GID+
Sbjct: 358 NPMESEFKGKKVLIVDDSIVRGTTSKEIVNMAKESGATKVYFASAAPAIRYNHIYGIDLT 417
Query: 391 TRHELIAAWRSIEDIRKEIGADSLAYLSIEGL 422
LIA R+ E++ + IG + + Y S+E L
Sbjct: 418 DTKNLIAYNRTDEEVAEVIGCERVIYQSLEDL 449
>gi|11435995 phosphoribosyl pyrophosphate amidotransferase [Homo sapiens]
Length = 450
Score = 250 bits (632), Expect = 2e-65
Identities = 158/405 (39%), Positives = 225/405 (55%), Gaps = 42/405 (10%)
Query: 6 GMREKCGIFGVSSE-------DAVRKTYYGLIALQHRGQEGAGISVWNGR----IRTIKG 54
G+RE+CG+FG + D GL+ LQHRGQE AGI +G ++ KG
Sbjct: 46 GIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKG 105
Query: 55 HGLVSEVFDENSLN--LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLT 110
GLV+ VF E++L SN+ IGH RY+T+G L QP V ++A+AHNG L
Sbjct: 106 MGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELV 165
Query: 111 NFIPLRRLYEGMGIKFHSSVDTEVIGISFLNHYSQVKDE----FEAMRRVFEEVKGAYSI 166
N LR+ GI +S D+E+I Q +D+ ++ + +E AYS+
Sbjct: 166 NAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPTAYSL 225
Query: 167 LILFDGKIIAARDPVGFRPLVFG----------------EGDGYYFASEDSALRMFGLET 210
LI+ I A RDP G RPL G E +G+ +SE + G
Sbjct: 226 LIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARY 285
Query: 211 -RDVLPGEVFVIDGESYES-KVLAREKH---AYCVFEYIYFARPDSTLNGINVYCARYRM 265
R+VLPGE+ I + ++ +++R + A+C+FEY+YFARPDS VY RYR
Sbjct: 286 YREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRC 345
Query: 266 GVELARESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMPSG--RG 323
G +LA E+P + D+V VP+S AAL +A + G+PY+E L KNRY+GRTFI P+ R
Sbjct: 346 GQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQ 405
Query: 324 LKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAR 368
L V K + + GKR+VLVDDSIVRG T++ I+K+L+++GA+
Sbjct: 406 LGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAK 450
>gb|AAK40942.1| Amidophosphoribosyltransferase (glutamine
phosphoribosylpyrophosphate amidotransferase) (ATase)
(GPAT) (purF-2) [Sulfolobus solfataricus]
Length = 404
Score = 215 bits (541), Expect = 1e-54
Identities = 148/442 (33%), Positives = 228/442 (51%), Gaps = 56/442 (12%)
Query: 12 GIFGVSSEDAV----RKTYYGLIALQHRGQEGAGISVWNGRIRTI-KGHGLVSEVFDENS 66
GI G+ + D V R YYGLI LQHRG +GI++ N + K + E +
Sbjct: 6 GILGILAFDDVWNVSRFLYYGLIGLQHRGYSKSGIAILNKQRNIFTKLENVAPEDLEIKD 65
Query: 67 LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
LN + I +R S Y + I NG +
Sbjct: 66 LNGWAGIGYAGIRNS-----------------YPITI-DNGAIV---------------- 91
Query: 127 HSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYS-ILILFDGKIIAARDPVGFRP 185
VD + + LNH + + +++K S I I DG++IA RD +G +P
Sbjct: 92 ---VDGMIDDNNVLNHVIREPEN------AIDDIKKPISFIAISKDGQLIAYRDELGLKP 142
Query: 186 LVFGEGDGYYFA---SEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAREKHAYCVF 241
L G G G+ A SE +++ + G E R++ PGE+ ++D ESK + + +YC
Sbjct: 143 LSIG-GFGFDLAVISSEPTSMFVIGAEFKREINPGELVIVDKYHIESKQVRIPRKSYCTI 201
Query: 242 EYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIP 301
EY+Y AR DS +N +Y R ++G ELA E P D VI VP++ A+G++ + IP
Sbjct: 202 EYVYQARIDSMINEREIYDLRVKIGEELALEYPINADSVIGVPETALPFAIGYSKKLNIP 261
Query: 302 YMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIV 359
G + RT + + + V+LKL+P++ V GKR++L+DDS+V GTT+ +
Sbjct: 262 LDLGFTRTGSPIRTMLSSDAFLKIVGVQLKLNPIKSAVKGKRIILIDDSMVTGTTLKNTI 321
Query: 360 KMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSI 419
LR GA+E+HV I SP + C G+++P ELI+A + E I + +GADS+ +LSI
Sbjct: 322 FNLRKLGAKEIHVLIGSPKLVSQCPYGVEVPDEKELISANLNDETIARVLGADSIHWLSI 381
Query: 420 EGLKRAVGTKNLCMACLTGEYP 441
EGL +A+G ++LC+ C+T +YP
Sbjct: 382 EGLFKAIGHRDLCLGCMTKKYP 403
>emb|CAB57667.1| (Y18930) amidophosphoribosyltransferase (ATASE), (glutamine
phosphoribosylpyrophosphate amidotransferase)
[Sulfolobus solfataricus]
Length = 404
Score = 215 bits (541), Expect = 1e-54
Identities = 148/442 (33%), Positives = 228/442 (51%), Gaps = 56/442 (12%)
Query: 12 GIFGVSSEDAV----RKTYYGLIALQHRGQEGAGISVWNGRIRTI-KGHGLVSEVFDENS 66
GI G+ + D V R YYGLI LQHRG +GI++ N + K + E +
Sbjct: 6 GILGILAFDDVWNVSRFLYYGLIGLQHRGYSKSGIAILNKQRNIFTKLENVAPEDLEIKD 65
Query: 67 LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
LN + I +R S Y + I NG +
Sbjct: 66 LNGWAGIGYAGIRNS-----------------YPITI-DNGAIV---------------- 91
Query: 127 HSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYS-ILILFDGKIIAARDPVGFRP 185
VD + + LNH + + +++K S I I DG++IA RD +G +P
Sbjct: 92 ---VDGMIDDNNVLNHVIREPEN------AIDDIKKPISFIAISKDGQLIAYRDELGLKP 142
Query: 186 LVFGEGDGYYFA---SEDSALRMFGLE-TRDVLPGEVFVIDGESYESKVLAREKHAYCVF 241
L G G G+ A SE +++ + G E R++ PGE+ ++D ESK + + +YC
Sbjct: 143 LSIG-GFGFDLAVISSEPTSMFVIGAEFKREINPGELVIVDKYHIESKQVRIPRKSYCTI 201
Query: 242 EYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGRTAALGFAHESGIP 301
EY+Y AR DS +N +Y R ++G ELA E P D VI VP++ A+G++ + IP
Sbjct: 202 EYVYQARIDSMINEREIYDLRVKIGEELALEYPINADSVIGVPETALPFAIGYSKKLNIP 261
Query: 302 YMEGLIKNRYIGRTFIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIV 359
G + RT + + + V+LKL+P++ V GKR++L+DDS+V GTT+ +
Sbjct: 262 LDLGFTRTGSPIRTMLSSDAFLKIVGVQLKLNPIKSAVKGKRIILIDDSMVTGTTLKNTI 321
Query: 360 KMLRDAGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRSIEDIRKEIGADSLAYLSI 419
LR GA+E+HV I SP + C G+++P ELI+A + E I + +GADS+ +LSI
Sbjct: 322 FNLRKLGAKEIHVLIGSPKLVSQCPYGVEVPDEKELISANLNDETIARVLGADSIHWLSI 381
Query: 420 EGLKRAVGTKNLCMACLTGEYP 441
EGL +A+G ++LC+ C+T +YP
Sbjct: 382 EGLFKAIGHRDLCLGCMTKKYP 403
>dbj|BAA16166.1| (D90863) AMIDOPHOSPHORIBOSYLTRANSFERASE (EC 2.4.2.14) (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE).
[Escherichia coli]
Length = 292
Score = 153 bits (384), Expect = 3e-36
Identities = 111/290 (38%), Positives = 154/290 (52%), Gaps = 25/290 (8%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVW--NGRIRTIKGHGLVSEVFDENSL 67
CGI G++ V ++ Y L LQHRGQ+ AGI N R K +GLVS+VF+ +
Sbjct: 1 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANGLVSDVFEARHM 60
Query: 68 N-LASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRR-LYEGMG 123
L N+ IGHVRY T+GS SE QP V Y + +AHNG LTN LR+ L+E
Sbjct: 61 QRLQGNMGIGHVRYPTAGSSSASEAQPFYVNS-PYGITLAHNGNLTNAHELRKKLFEEKR 119
Query: 124 IKFHSSVDTEVIGISFLN------HYSQVKDE-FEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+E++ F + HY D F A+ ++GAY+ + + G ++
Sbjct: 120 RHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMV 179
Query: 176 AARDPVGFRPLVFGEGD------GYYFASEDSALRMFGLE-TRDVLPGEVFVI--DGESY 226
A RDP G RPLV G+ D Y ASE AL G + RDV PGE I +G+ +
Sbjct: 180 AFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLGFDFLRDVAPGEAIYITEEGQLF 239
Query: 227 ESKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAE 276
+ C+FEY+YFARPDS ++ I+VY AR MG +L + E
Sbjct: 240 TRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARVNMGTKLGEKIARE 289
>dbj|BAB13799.1| (AB031231) glutamine phosphoribosylpyrophosphate amidotransferase
[Pseudomonas aeruginosa]
Length = 281
Score = 153 bits (383), Expect = 4e-36
Identities = 106/282 (37%), Positives = 155/282 (54%), Gaps = 25/282 (8%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGI-SVWNGRIRTIKGHGLVSEVFDENSLN 68
CGI G+ + V + Y L LQHRGQ+ AGI + + ++ K +GLV +VF + +
Sbjct: 2 CGIVGIVGKSNVNQALYDALTVLQHRGQDAAGIVTCHDDKLYLRKDNGLVRDVFQQRHMQ 61
Query: 69 -LASNIAIGHVRYSTSGSLS--EVQPLEVRCCGYELAIAHNGTLTNFIPL-RRLYEGMGI 124
L ++ IGHVRY T+GS S E QP V Y + +AHNG LTN L + +YE
Sbjct: 62 RLIGSVGIGHVRYPTAGSSSSAEAQPFYVNS-PYGITLAHNGNLTNVEQLAKEIYESDLR 120
Query: 125 KFHSSVDTEVIGISFLNHYSQVK--------DEFEAMRRVFEEVKGAYSILILFDGK-II 175
+++ D+EV+ ++ H V+ D F A+ V + G Y+++ + G I+
Sbjct: 121 HVNTNSDSEVL-LNVFAHELAVRNKLQPTEEDIFAAVSCVHDRCVGGYAVVAMITGHGIV 179
Query: 176 AARDPVGFRPLVFGE-----GDGYYFASEDSALRMFGLET-RDVLPGEVFVI--DGESYE 227
RDP RP+VFG+ G Y ASE AL + G RD+ PGE I +G+ Y
Sbjct: 180 GFRDPNAIRPIVFGQRHTENGVEYMIASESVALDVLGFTLIRDLAPGEAVYITEEGKLYT 239
Query: 228 SKVLAREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVEL 269
+ K+A C+FE++Y ARPDS ++GI+VY AR RMG +L
Sbjct: 240 RQCAKAPKYAPCIFEHVYLARPDSIMDGISVYKARLRMGEKL 281
>sp|Q51342|PUR1_PSEAE AMIDOPHOSPHORIBOSYLTRANSFERASE (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|607831|gb|AAA83434.1| (U10904) glutamine
phosphoribosylpyrophosphate amidotransferase
[Pseudomonas aeruginosa]
Length = 216
Score = 152 bits (379), Expect = 1e-35
Identities = 82/159 (51%), Positives = 106/159 (66%), Gaps = 2/159 (1%)
Query: 271 RESPAEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKNRYIGRTFIMP--SGRGLKVKL 328
R S + DVVI +PD+ RTA L A+ G+ + EG +KNRYIGRTFIMP + R V+
Sbjct: 3 RASDHDIDVVIPIPDTSRTARLELANRLGVKFREGFVKNRYIGRTFIMPGQAARKKSVRQ 62
Query: 329 KLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRDAGAREVHVRIASPPIRYPCYMGID 388
KL+ + GK V+LVDDSIVRGTT +I++M R+AGA+ V+ A+P +RYP GID
Sbjct: 63 KLNAIELEFRGKNVMLVDDSIVRGTTCKQIIQMAREAGAKNVYFCSAAPAVRYPNVYGID 122
Query: 389 IPTRHELIAAWRSIEDIRKEIGADSLAYLSIEGLKRAVG 427
+P+ HELIA RS ED+ K IGAD L Y + L AVG
Sbjct: 123 MPSAHELIAHNRSTEDVSKLIGADWLVYQDLPDLIDAVG 161
>sp|P35853|PUR1_LACCA AMIDOPHOSPHORIBOSYLTRANSFERASE PRECURSOR (GLUTAMINE
PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE)
(GPATASE) >gi|625915|pir||PC1136
amidophosphoribosyltransferase (EC 2.4.2.14) precursor -
Lactobacillus casei (fragment) >gi|551881|gb|AAC36948.1|
(M85265) amidophosphoribosyltransferase [Lactobacillus
casei]
Length = 194
Score = 126 bits (314), Expect = 4e-28
Identities = 80/191 (41%), Positives = 106/191 (54%), Gaps = 8/191 (4%)
Query: 5 RGMREKCGIFGV-SSEDAVRKTYYGLIALQHRGQEGAGI-SVWNGRIRTIKGHGLVSEVF 62
+G+ E+CG+FGV + +A T+ GL LQHRGQEGAGI + +R G GL+SEVF
Sbjct: 6 KGLNEECGVFGVWGNPNAASITHLGLHTLQHRGQEGAGIVGLTKDGMRRHYGLGLLSEVF 65
Query: 63 DENS--LNLASNIAIGHVRYSTSGS--LSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRL 118
L A+GHVRYST+G L +QPL R +A+AHNG LTN I LRR
Sbjct: 66 TNTDQLTPLIGRAALGHVRYSTAGGRVLENIQPLLFRFSDEAIALAHNGNLTNAISLRRQ 125
Query: 119 YEGMGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAAR 178
E G F S+ DTEV+ Q ++ EV G ++ ++L + + AA
Sbjct: 126 LEDQGAIFQSTSDTEVLMHLIRRQVGQ--PWLTQLKTALNEVHGGFAFVLLTEHGLYAAV 183
Query: 179 DPVGFRPLVFG 189
DP GFRP+V G
Sbjct: 184 DPHGFRPMVVG 194
>gb|AAK40710.1| Glutamine-fructose-6-phosphate transaminase (isomerizing) (glmS-1)
[Sulfolobus solfataricus]
Length = 591
Score = 92.8 bits (227), Expect = 7e-18
Identities = 67/223 (30%), Positives = 108/223 (48%), Gaps = 19/223 (8%)
Query: 11 CGIFGVSSEDAVRKTYYGLIA----LQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDEN 65
CGI G+ S + +++ L++RG + G++ +G + K G V EV +
Sbjct: 2 CGIIGIVSNKESNRLAELVVSCLNRLEYRGYDSVGVAALSGGNLEVRKAKGTVEEVVRKK 61
Query: 66 SLNLASNIA-IGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
++ S A +GH R++T G+ ++ C +A+ HNGT+ NF LR + +G
Sbjct: 62 NIKELSGYAFLGHTRWATHGAPTDYNAHPHTDCINNIAVIHNGTIRNFKELRDELQALGH 121
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGK---IIAARDPV 181
KF S DTEVI + + D F+A R + ++G+Y++L + G+ A RD
Sbjct: 122 KFKSETDTEVIPHMMEEYMKRGMDTFQAFRSAIKNIQGSYAVLAIVKGERRIFFAKRD-- 179
Query: 182 GFRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVIDGE 224
PLV G GD F + D + F TR V + + DGE
Sbjct: 180 --NPLVIGLGDDKTFVASD--IPSFLPYTRKV----IVISDGE 214
>sp|Q56275|GLMS_THIFE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|11259069|pir||T45493 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) glmS
[similarity] - Thiobacillus ferrooxidans
>gi|2654003|gb|AAC21670.1| (AF032884) glucosamine
synthase [Acidithiobacillus ferrooxidans]
Length = 611
Score = 91.3 bits (223), Expect = 2e-17
Identities = 73/218 (33%), Positives = 108/218 (49%), Gaps = 21/218 (9%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNG-----RIRTIKGHGLVSEVFDE 64
CGI G VS D V GL L++RG + AG+++ R+R++ ++ E
Sbjct: 2 CGIVGGVSKTDLVPMILEGLQRLEYRGYDSAGLAILGADADLLRVRSVGRVAELTAAVVE 61
Query: 65 NSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
L + IGH R++T G + E + ++A+ HNG + NF LR E G
Sbjct: 62 RGLQ--GQVGIGHTRWATHGGVRECNAHPM-ISHEQIAVVHNGIIENFHALRAHLEAAGY 118
Query: 125 KFHSSVDTEVIGISFLNHYSQ-VKDEFEAMRRVFEEVKGAYSILILFDG---KIIAARDP 180
F S DTEVI ++HY Q D F A RR +++GAY+I ++ G + AR
Sbjct: 119 TFTSETDTEVIA-HLVHHYRQTAPDLFAATRRAVGDLRGAYAIAVISSGDPETVCVAR-- 175
Query: 181 VGFRPLVFGEGDGYYFASEDSAL-----RMFGLETRDV 213
+G L+ DG+YFAS+ +AL R+ LE DV
Sbjct: 176 MGCPLLLGVADDGHYFASDVAALLPVTRRVLYLEDGDV 213
>sp|O84823|GLMS_CHLTR GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434171|pir||B71467 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) - Chlamydia
trachomatis (serotype D, strain UW3/Cx)
>gi|3329285|gb|AAC68413.1| (AE001354)
Glucosamine-Fructose-6-P Aminotransferase [Chlamydia
trachomatis]
Length = 606
Score = 91.3 bits (223), Expect = 2e-17
Identities = 68/237 (28%), Positives = 108/237 (44%), Gaps = 7/237 (2%)
Query: 11 CGIFGVSSE-DAVRKTYYGLIALQHRGQEGAGISVW-NGRIRTIKGHGLVSEVFDENSLN 68
CGIFG E +AV GL L++RG + AGI+ GR+ K G VS++ S +
Sbjct: 2 CGIFGYLGEKNAVPLVLEGLSKLEYRGYDSAGIATLVEGRLFVEKAVGPVSQLCSAVSSD 61
Query: 69 LASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFHS 128
+ S AIGH R++T G S A+ HNG + NF L+ E G+ F S
Sbjct: 62 IHSQAAIGHTRWATHGEPSRFNAHPHVDMDASCALVHNGIIENFQKLKEELEEQGVVFSS 121
Query: 129 SVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFRPLVF 188
DTEVI F Y + +D ++ + ++G+++ ++ PL+
Sbjct: 122 DTDTEVIVQLFARRYKETRDLIQSFSWTLKRLQGSFACALMHQDHPEVLLCAAHESPLIL 181
Query: 189 GEGDGYYFASED-SALRMFGLETRDVLPGEVFVI----DGESYESKVLAREKHAYCV 240
G G+ F S D A + T+ + GE+ V+ E+Y ++ +K C+
Sbjct: 182 GLGEDEVFISSDIHAFLKYSGCTQTLASGELAVLRIGKSIETYNFELARIQKEVRCI 238
>pir||D71248 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) PH0243 [similarity] - Pyrococcus horikoshii
>gi|3256632|dbj|BAA29315.1| (AP000001) 601aa long
hypothetical glutamine--fructose-6-phosphate
aminotransferase [Pyrococcus horikoshii]
Length = 601
Score = 88.9 bits (217), Expect = 1e-16
Identities = 73/226 (32%), Positives = 108/226 (47%), Gaps = 19/226 (8%)
Query: 7 MREKCGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISV-WNGRIRTIKGHGLVSEVFDE 64
M CGI G + A GL L++RG + AGI+ + G+I KG G + E+ +
Sbjct: 1 MENVCGIIGYIGPRKASDVIVEGLKRLEYRGYDSAGIATCYEGKIFIKKGAGKIDELVKK 60
Query: 65 -NSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMG 123
N L L NI IGH R++T G ++ C ++ + HNG + NF L+R G
Sbjct: 61 LNFLELPGNIGIGHTRWATHGIPNDTNAHPHTDCTGKIVVVHNGIIENFQELKRELLKRG 120
Query: 124 IKFHSSVDTEVIGISFLNHYSQVKDEFE-AMRRVFEEVKGAYSILILF----DGKIIAAR 178
F S DTEVI + ++ FE A R ++G+Y++++LF + IA +
Sbjct: 121 HVFRSDTDTEVIA-HLIEENLRITGNFEDAFRMSLLRLRGSYALVVLFADDPERLYIARK 179
Query: 179 DPVGFRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVIDGE 224
D PL+ G G G F + D + F TR VF+ DGE
Sbjct: 180 D----SPLIIGIGKGEMFMASD--IPAFLAYTRRA----VFLDDGE 215
>sp|O57981|GLMS_PYRHO GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
Length = 598
Score = 87.8 bits (214), Expect = 2e-16
Identities = 72/222 (32%), Positives = 107/222 (47%), Gaps = 19/222 (8%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISV-WNGRIRTIKGHGLVSEVFDE-NSL 67
CGI G + A GL L++RG + AGI+ + G+I KG G + E+ + N L
Sbjct: 2 CGIIGYIGPRKASDVIVEGLKRLEYRGYDSAGIATCYEGKIFIKKGAGKIDELVKKLNFL 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
L NI IGH R++T G ++ C ++ + HNG + NF L+R G F
Sbjct: 62 ELPGNIGIGHTRWATHGIPNDTNAHPHTDCTGKIVVVHNGIIENFQELKRELLKRGHVFR 121
Query: 128 SSVDTEVIGISFLNHYSQVKDEFE-AMRRVFEEVKGAYSILILF----DGKIIAARDPVG 182
S DTEVI + ++ FE A R ++G+Y++++LF + IA +D
Sbjct: 122 SDTDTEVIA-HLIEENLRITGNFEDAFRMSLLRLRGSYALVVLFADDPERLYIARKD--- 177
Query: 183 FRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVIDGE 224
PL+ G G G F + D + F TR VF+ DGE
Sbjct: 178 -SPLIIGIGKGEMFMASD--IPAFLAYTRRA----VFLDDGE 212
>pir||H82022 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) NMA0276 [similarity] - Neisseria meningitidis
(group A strain Z2491) >gi|7379038|emb|CAB83584.1|
(AL162752) glucosamine--fructose-6-phosphate
aminotransferase [isomerizing] [Neisseria meningitidis
Z2491]
Length = 612
Score = 87.4 bits (213), Expect = 3e-16
Identities = 67/219 (30%), Positives = 112/219 (50%), Gaps = 11/219 (5%)
Query: 11 CGIFGV--SSEDAVRKTYYGLIALQHRGQEGAGISV-WNGRIRTIKGHGLVSEVFDE-NS 66
CGI G + + V GL L++RG + +GI+V +G+I+ ++ G V + D
Sbjct: 2 CGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIKRVRRVGRVQLMEDAARE 61
Query: 67 LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
++ I IGH R++T G ++E G +A+ HNG + NF R+ EG+G +F
Sbjct: 62 KGISGGIGIGHTRWATHGGVTEPNA-HPHISGGMIAVVHNGIIENFESERKRLEGLGYRF 120
Query: 127 HSSVDTEVIGISFLNHYSQVKDE-FEAMRRVFEEVKGAYSILILFDGK---IIAARDPVG 182
S DTEVI S + Y+Q + FEA++ + GAY+I ++ K ++ AR +G
Sbjct: 121 ESQTDTEVIAHSINHEYAQNGGKLFEAVQEAVKRFHGAYAIAVIAQDKPDELVVAR--MG 178
Query: 183 FRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVI 221
LV D + AS+ SA+ F + G++ ++
Sbjct: 179 CPLLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALL 217
>pir||B81246 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) NMB0031 [similarity] - Neisseria meningitidis
(group B strain MD58) >gi|7225250|gb|AAF40502.1|
(AE002361) glucosamine--fructose-6-phosphate
aminotransferase (isomerizing) [Neisseria meningitidis
MC58]
Length = 612
Score = 87.0 bits (212), Expect = 4e-16
Identities = 67/219 (30%), Positives = 111/219 (50%), Gaps = 11/219 (5%)
Query: 11 CGIFGV--SSEDAVRKTYYGLIALQHRGQEGAGISV-WNGRIRTIKGHGLVSEVFDE-NS 66
CGI G + + V GL L++RG + +GI+V +G+I+ ++ G V + D
Sbjct: 2 CGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIKRVRRVGRVQLMEDAARE 61
Query: 67 LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
++ I IGH R++T G ++E G +A+ HNG + NF R+ EG+G +F
Sbjct: 62 KGISGGIGIGHTRWATHGGVTEPNA-HPHISGGMIAVVHNGIIENFESERKRLEGLGYRF 120
Query: 127 HSSVDTEVIGISFLNHYSQVKDE-FEAMRRVFEEVKGAYSILILFDGK---IIAARDPVG 182
S DTEVI S + Y+Q FEA++ + GAY+I ++ K ++ AR +G
Sbjct: 121 ESQTDTEVIAHSINHEYAQNGGRLFEAVQEAVKRFHGAYAIAVIAQDKPDELVVAR--MG 178
Query: 183 FRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVI 221
LV D + AS+ SA+ F + G++ ++
Sbjct: 179 CPLLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALL 217
>pir||G75092 asparagine synthase (glutamine-hydrolyzing) (EC 6.3.5.4) PAB0750
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5458556|emb|CAB50044.1| (AJ248286) asparagine
synthetase, putative [Pyrococcus abyssi]
Length = 479
Score = 86.2 bits (210), Expect = 7e-16
Identities = 69/212 (32%), Positives = 103/212 (48%), Gaps = 22/212 (10%)
Query: 12 GIFGVSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSEVFDENSLNLAS 71
G F VS EDA++ G +HRG + G W+ R L S+ F + S
Sbjct: 6 GGFNVSREDAIKIINLG----KHRGPDSFGF--WSER------QMLKSDNFSDVSEIEGG 53
Query: 72 NIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFHSSVD 131
IA+ R + +GS S QP E+ + HNG + N LR+ G+ F + VD
Sbjct: 54 EIALIQCRLAMTGSKSYTQPFY-----NEIILVHNGEIYNHESLRKYLIERGVAFETDVD 108
Query: 132 TEVIG--ISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFRPLVFG 189
+EVI + +L ++K E EA++ + ++G Y++ F+GK RDP+G RPL +
Sbjct: 109 SEVILRLLEYLVFDRKLKVE-EAIKLSMKMLRGDYAVAFFFNGKFYLFRDPLGVRPLYYS 167
Query: 190 EGDGYYFASEDSALRMFGLETRDVLPGEVFVI 221
+FASE L G + VLPGE+ I
Sbjct: 168 SRG--HFASEKKVLWGLGEDAEPVLPGEIVSI 197
>sp|O86781|GLMS_STRCO GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7479247|pir||T35569 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) SC6G4.18
[similarity] - Streptomyces coelicolor
>gi|3449252|emb|CAA20396.1| (AL031317)
glucosamine--fructose-6-phosphate aminotransfera se
[Streptomyces coelicolor A3(2)]
Length = 615
Score = 85.8 bits (209), Expect = 9e-16
Identities = 69/212 (32%), Positives = 103/212 (48%), Gaps = 14/212 (6%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVW-NGRIRTIKGHGLVSEVFDENSLN 68
CGI G V + A+ GL L++RG + AG++V +G + T K G + + E S +
Sbjct: 2 CGIVGYVGPQSALDVVMAGLKRLEYRGYDSAGVAVLADGGLATAKRAGKLVNLDKELSEH 61
Query: 69 L--ASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
A+ IGH R++T G ++ +A+ HNG + NF PLR G +
Sbjct: 62 PLPAAATGIGHTRWATHGGPTDANAHPHLDNAGRVAVVHNGIIENFAPLRAELAERGHEL 121
Query: 127 HSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILF----DGKIIAARDPVG 182
S DTEV+ YS D EAMR V ++GA++++ + D + A R+
Sbjct: 122 PSETDTEVVAHLLAEEYSACADLAEAMRLVCGRLEGAFTLVAVHADAPDVVVGARRN--- 178
Query: 183 FRPLVFGEGDGYYFASEDSALRMFGLETRDVL 214
PLV G G+G YF + D A F TRD +
Sbjct: 179 -SPLVVGVGEGEYFLASDVA--AFIAHTRDAV 207
>pir||B81729 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) TC0203 [similarity] - Chlamydia muridarum
(strain Nigg) >gi|7190240|gb|AAF39075.1| (AE002287)
glucosamine--fructose-6-phosphate aminotransferase
(isomerizing) [Chlamydia muridarum]
Length = 606
Score = 85.4 bits (208), Expect = 1e-15
Identities = 64/237 (27%), Positives = 109/237 (45%), Gaps = 7/237 (2%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGIS-VWNGRIRTIKGHGLVSEVFDENSLN 68
CGIFG + +AV GL L++RG + AGI+ + + K G VS++ + S +
Sbjct: 2 CGIFGYLGQRNAVPLVLEGLSKLEYRGYDSAGIAALTKDHLFVEKSVGPVSQLCSKVSSD 61
Query: 69 LASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFHS 128
+ S +AIGH R++T G S A+ HNG + NF LR G++F S
Sbjct: 62 MHSQVAIGHTRWATHGEPSRFNAHPHVDMYESCALVHNGIIENFQTLREDLSSKGVEFSS 121
Query: 129 SVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFRPLVF 188
DTEVI F + Y + D ++ ++++G+++ ++ PL+
Sbjct: 122 DTDTEVIVQLFASRYRETGDLVQSFSWTLKQLQGSFACALVHQDHPEILLCATYESPLIL 181
Query: 189 GEGDGYYFASED-SALRMFGLETRDVLPGEVFVI----DGESYESKVLAREKHAYCV 240
G G+ F S D A + + + + GE+ V+ E Y ++ +K C+
Sbjct: 182 GLGEEEVFISSDVHAFLKYSCQIQTLASGELAVLRIGRPVEIYNFELSRIQKEVRCI 238
>sp|O26273|GLMS_METTH GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434168|pir||G69095 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621214|gb|AAB84677.1| (AE000805)
glutamine-fructose-6-phosphate transaminase
[Methanobacterium thermoautotrophicum]
Length = 590
Score = 84.7 bits (206), Expect = 2e-15
Identities = 63/215 (29%), Positives = 102/215 (47%), Gaps = 12/215 (5%)
Query: 32 LQHRGQEGAGISVWNGRIRTIKGHGLVSEVFDENSL-NLASNIAIGHVRYSTSGSLSEVQ 90
L++RG + GI+ + IR K G + EV E L +L + I HVR++T G +
Sbjct: 25 LEYRGYDSVGIATSDPMIRIKKDSGKIDEVDAELDLADLPGTMGIAHVRWATHGLPTAEN 84
Query: 91 PLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFHSSVDTEVIGISFLNHYSQVKDEF 150
C E+A+ HNG + N++ ++ E G F S DTEVI + + D
Sbjct: 85 AHPHTDCSGEIAVVHNGIIENYLEVKEELESEGHIFRSETDTEVIPHLIEKYMDEGMDLE 144
Query: 151 EAMRRVFEEVKGAYSILILFD---GKIIAARDPVGFRPLVFGEGDGYYF-ASEDSALRMF 206
A +++GAY+I + G+I+ AR PL+ G G+G YF AS+ A+
Sbjct: 145 AATATALRKLRGAYAIAAVSSREPGRIVGARKE---SPLIVGVGEGEYFLASDVPAILNH 201
Query: 207 GLETRDVLPGEVFVIDGE----SYESKVLAREKHA 237
+ GE+ ++DG+ E + +E H+
Sbjct: 202 TSRVIYLDDGEMVILDGDLRVTDMEGNTVEKEVHS 236
>gi|9631669 PBCV-1 glucosamine synthetase [Paramecium bursaria Chlorella virus
1] >gi|7461867|pir||T17590 probable
glutamine--fructose-6-phosphate transaminase
(isomerizing) (EC 2.6.1.16) - Chlorella virus PBCV-1
>gi|1131444|gb|AAC96468.1| (U42580) PBCV-1 glucosamine
synthetase [Paramecium bursaria Chlorella virus 1]
Length = 595
Score = 83.9 bits (204), Expect = 3e-15
Identities = 67/208 (32%), Positives = 109/208 (52%), Gaps = 24/208 (11%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNG----RIRTIKGHGLVSEVFDEN 65
CGIFG VS+ +++ + G+ L++RG + GI+ +G RIR+I G + +
Sbjct: 2 CGIFGAVSNNNSIEVSIKGIQKLEYRGYDSCGIAYTDGGAIERIRSIDG----IDDLRKK 57
Query: 66 SLNLASNIAIGHVRYSTSG--SLSEVQPLEVRC---CGYELAIAHNGTLTNFIPLRRLYE 120
++ +S +AI H R+ST+G S+ P R C +A+ HNG + N+ +R+
Sbjct: 58 TITESSPVAIAHSRWSTTGIPSVVNAHPHISRGTSGCESRIAVVHNGIIENYQQIRKYLI 117
Query: 121 GMGIKFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILF---DGKIIAA 177
+G F S DTEVI + Y+ + ++ + +KG+Y+I ++ GKI+ A
Sbjct: 118 NLGYTFDSQTDTEVIAHLIDSQYN--GNILHTVQMAVKHLKGSYAIAVMCHKESGKIVVA 175
Query: 178 RDPVGFRPLVFGEG-DG-YYFASEDSAL 203
+ PLV G G DG YY AS+ AL
Sbjct: 176 KQK---SPLVLGIGSDGAYYIASDVLAL 200
>sp|Q56213|GLMS_THETH GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|2145506|pir||S69793 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) - Thermus
aquaticus >gi|1184044|gb|AAA86988.1| (U17352)
L-glutamine:D-fructose-6-P amidotransferase precursor
[Thermus thermophilus]
Length = 604
Score = 82.7 bits (201), Expect = 8e-15
Identities = 60/195 (30%), Positives = 98/195 (49%), Gaps = 10/195 (5%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEVFDE-NSL 67
CGI G V +A GL L++RG + AGI+V ++ +K G +S + +
Sbjct: 2 CGIVGYVGFRNATDVLLDGLRRLEYRGYDSAGIAVRTPEGLKVVKRSGKLSSLAEAVGKT 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
L + IGH R++T G+ ++ +A+ HNG N++ L+ E G +F
Sbjct: 62 PLQGALGIGHTRWATHGAPTDPNAHPHTTEDGRIALIHNGIFENYLELKEALEARGHRFR 121
Query: 128 SSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDG--KIIAARDPVGFRP 185
S DTEV ++ L + D EA+R + V+GAY++++ + +I+AAR P
Sbjct: 122 SETDTEV--LAHLLEETYRGDLLEALREALKAVRGAYAVVVAHEDHEEIVAART---VSP 176
Query: 186 LVFGEGDGYYFASED 200
LV G G+G F + D
Sbjct: 177 LVVGLGEGENFLASD 191
>pir||F82951 glucosamine--fructose-6-phosphate aminotransferase PA5549
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9951889|gb|AAG08934.1|AE004967_5 (AE004967)
glucosamine--fructose-6-phosphate aminotransferase
[Pseudomonas aeruginosa]
Length = 611
Score = 81.5 bits (198), Expect = 2e-14
Identities = 67/203 (33%), Positives = 106/203 (52%), Gaps = 14/203 (6%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVWN--GRIRTIKGHGLVSEVFDENS- 66
CGI G +E + GL L++RG + AG++V++ GR++ + G V+ + + +
Sbjct: 2 CGIVGAIAERNITPILIEGLKRLEYRGYDSAGVAVFDNEGRLQRCRRVGKVASLEEGLAG 61
Query: 67 LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
L + I H R++T G+ +E E+A+ HNG + N PLR +G+G F
Sbjct: 62 TPLLGRLGIAHTRWATHGAPTEGNA-HPHFSSDEVAVVHNGIIENHEPLRERLKGLGYVF 120
Query: 127 HSSVDTEVIGISFLNHYSQ-VKDEFEAMRRVFEEVKGAYSILILF---DGKIIAARDPVG 182
S DTEVI + L+H Q + D A++ +E+ GAY + ++ +I+AAR
Sbjct: 121 TSQTDTEVI-VHLLHHKLQSIGDLTLALKDAVKELHGAYGLAVISAAQPDRIVAARSG-- 177
Query: 183 FRPLVFGEGDGYYF-ASEDSALR 204
PLV G G G F AS+ ALR
Sbjct: 178 -SPLVIGLGLGENFLASDQLALR 199
>pir||F75212 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) PAB2201 - Pyrococcus abyssi (strain Orsay)
>gi|5457658|emb|CAB49149.1| (AJ248283)
Glucosamine--fructose-6-phosphate aminotransferase
[Pyrococcus abyssi]
Length = 598
Score = 81.1 bits (197), Expect = 2e-14
Identities = 69/222 (31%), Positives = 106/222 (47%), Gaps = 19/222 (8%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWN-GRIRTIKGHGLVSEVFDE-NSL 67
CGI G + A GL L++RG + AGI+ + GRI KG G + E+ N
Sbjct: 2 CGIIGYIGPRKASPIIVEGLKRLEYRGYDSAGIATSHEGRILIKKGAGKIDELAKRLNFT 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
+L NI IGH R++T G ++ C ++ + HNG + NF L+ G F
Sbjct: 62 DLPGNIGIGHTRWATHGIPNDTNAHPHTDCTGKIVVVHNGIIENFQELKEELLRQGHVFR 121
Query: 128 SSVDTEVIGISFLNHYSQVKDEFE-AMRRVFEEVKGAYSILILF----DGKIIAARDPVG 182
S DTEVI + ++ FE A R ++G+++++++F + IA +D
Sbjct: 122 SDTDTEVIA-HLIEENLRITGNFEDAFRLSLLRLRGSFALVVMFADDPERLYIARKD--- 177
Query: 183 FRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVIDGE 224
PL+ G G+G F + D + F TR VF+ DGE
Sbjct: 178 -SPLIIGIGNGEMFIASD--IPAFLPYTRKA----VFLDDGE 212
>sp|O68956|GLMS_MYCSM GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|3065833|gb|AAC14295.1| (AF058788)
L-glutamine:D-fructose-6-phosphate amidotransferase
[Mycobacterium smegmatis]
Length = 628
Score = 80.8 bits (196), Expect = 3e-14
Identities = 80/297 (26%), Positives = 124/297 (40%), Gaps = 25/297 (8%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVWNGR----IRTIKGH-----GLVSE 60
CGI G R L +++RG + AGI++ +G +R G ++E
Sbjct: 2 CGIVGYVGHRPARDIVVDALRRMEYRGYDSAGIALIDGNGGLTVRRRAGRLANLEATLAE 61
Query: 61 VFDENSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYE 120
+ L + +GH R++T G ++ R ++A+ HNG + NF PLR E
Sbjct: 62 TDSNDGDGLGGSTGLGHTRWATHGRPTDRNAHPHRDAAGKIAVVHNGIIENFAPLRAELE 121
Query: 121 GMGIKFHSSVDTEVIGISFLNHYSQ--VKDEFEA-MRRVFEEVKGAYSILILF---DGKI 174
G++F S DTEV Y+Q +F A + V + ++G ++++ G I
Sbjct: 122 AAGVEFASDTDTEVAVHLVARQYTQGDTAGDFPASVLAVLQRLEGHFTLVFASADDPGTI 181
Query: 175 IAARDPVGFRPLVFGEGDGYYFASEDSALRMFGLETRDVL---PGEVFVIDGESYESKVL 231
+AAR PLV G GDG F D A F TRD + + V+ + Y
Sbjct: 182 VAARRST---PLVLGIGDGEMFVGSDVA--AFIEHTRDAVELGQDQAVVLTADGYRITDF 236
Query: 232 AREKHAYCVFEYIYFARPDSTLNGINVYCARYRMGVELARESPAEGDVVIAVPDSGR 288
A H ++ F D LN Y M E+A + A D ++ D R
Sbjct: 237 AGNDHLEAGRDFREF-HIDWDLNAAEKGGYDYFMLKEIAEQPSAVADTLLGHFDKNR 292
>pir||A72592 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) APE1205 [similarity] - Aeropyrum pernix
(strain K1) >gi|5104877|dbj|BAA80191.1| (AP000061) 625aa
long hypothetical glucosamine--fructose-6-phosphate
aminotransferase [Aeropyrum pernix]
Length = 625
Score = 80.4 bits (195), Expect = 4e-14
Identities = 58/200 (29%), Positives = 93/200 (46%), Gaps = 14/200 (7%)
Query: 11 CGIFGVS---SEDAVRKTYYGLIALQHRGQEGAGISVWN--GRIRTIKGHGLVSEVFDEN 65
CGI G++ GL L++RG + G++V GR+ K G + EV
Sbjct: 10 CGIIGLAFAEGNSVAGALVRGLKRLEYRGYDSMGVAVIEPPGRLVVRKAAGKIGEVVRRT 69
Query: 66 S-LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
L+L + IGH R++T G ++V CG +A+ HNG + N+ LRR E G
Sbjct: 70 GVLSLRGRVGIGHTRWATHGPPNDVNAHPHTDCGGRVAVVHNGVIRNYASLRRELEARGH 129
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGF- 183
+ S DTE++ + + EA+ + ++G+Y++ +L G+ D V F
Sbjct: 130 RLVSETDTELVAHLIEEYLGRGYSFLEALSLLGRVLRGSYALALLHLGE----PDKVYFL 185
Query: 184 ---RPLVFGEGDGYYFASED 200
PLV G G+G + D
Sbjct: 186 RYKSPLVVGLGEGVNAVASD 205
>emb|CAB87226.1| (AL163641) glucosamine-fructose-6-phosphate aminotransferase
[Streptomyces coelicolor A3(2)]
Length = 605
Score = 80.4 bits (195), Expect = 4e-14
Identities = 58/199 (29%), Positives = 94/199 (47%), Gaps = 12/199 (6%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNGR---IRTIKGHGLVSEVFDENS 66
CGI G + D GL L++RG + AGI V + + +R +K G V ++ +
Sbjct: 2 CGIVGYIGKRDVAPLLLEGLQRLEYRGYDSAGIVVTSPKAAGLRMVKAKGRVRDLEAKVP 61
Query: 67 LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
I H R++T G+ S+V ++A+ HNG + N LRR E G++F
Sbjct: 62 ARFKGTTGIAHTRWATHGAPSDVNAHPHMSADNKVAVVHNGIIDNAADLRRKLEADGVEF 121
Query: 127 HSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILIL---FDGKIIAARDPVGF 183
S DTEV + L S+ + + +R ++G Y I ++ F +I+ AR+
Sbjct: 122 LSETDTEV--LVHLIARSEAEKLEDKVRETLRVIEGTYGIAVMHADFPERIVVARNG--- 176
Query: 184 RPLVFGEGDGYYFASEDSA 202
P+V G G+ F + D A
Sbjct: 177 SPVVLGIGEKEMFVASDIA 195
>sp|Q9YCQ6|GLMS_AERPE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
Length = 617
Score = 80.4 bits (195), Expect = 4e-14
Identities = 58/200 (29%), Positives = 93/200 (46%), Gaps = 14/200 (7%)
Query: 11 CGIFGVS---SEDAVRKTYYGLIALQHRGQEGAGISVWN--GRIRTIKGHGLVSEVFDEN 65
CGI G++ GL L++RG + G++V GR+ K G + EV
Sbjct: 2 CGIIGLAFAEGNSVAGALVRGLKRLEYRGYDSMGVAVIEPPGRLVVRKAAGKIGEVVRRT 61
Query: 66 S-LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
L+L + IGH R++T G ++V CG +A+ HNG + N+ LRR E G
Sbjct: 62 GVLSLRGRVGIGHTRWATHGPPNDVNAHPHTDCGGRVAVVHNGVIRNYASLRRELEARGH 121
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGF- 183
+ S DTE++ + + EA+ + ++G+Y++ +L G+ D V F
Sbjct: 122 RLVSETDTELVAHLIEEYLGRGYSFLEALSLLGRVLRGSYALALLHLGE----PDKVYFL 177
Query: 184 ---RPLVFGEGDGYYFASED 200
PLV G G+G + D
Sbjct: 178 RYKSPLVVGLGEGVNAVASD 197
>sp|P25195|NODM_RHIME GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(GFAT) (NODULATION PROTEIN M) >gi|95201|pir||S16561
glutamine--fructose-6-phosphate transaminase
(isomerizing) (EC 2.6.1.16) - Rhizobium meliloti
>gi|46332|emb|CAA41485.1| (X58632)
glucosamine--fructose-6-phosphate aminotransferase
(isomerizing) [Sinorhizobium meliloti]
>gi|228195|prf||1718309A nodM gene [Rhizobium meliloti]
Length = 605
Score = 79.6 bits (193), Expect = 7e-14
Identities = 63/218 (28%), Positives = 103/218 (46%), Gaps = 13/218 (5%)
Query: 11 CGIFGVSSEDAV-RKTYYGLIALQHRGQEGAGISVWN-GRIRTIKGHGLVSEVFDE-NSL 67
CGI G+ V + L L++RG + AG++ + G ++ + G + + ++
Sbjct: 2 CGIVGIVGHQPVSERLVEALEPLEYRGYDSAGVATMDAGTLQRRRAEGKLGNLREKLKEA 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
L+ I I H R++T G+ +E G +A+ HNG + NF L+ G +F
Sbjct: 62 PLSGTIGIAHTRWATHGAPTERNAHPHFTEG--VAVVHNGIIENFAELKDELAAGGAEFQ 119
Query: 128 SSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFD---GKIIAARDPVGFR 184
+ DTEV+ + EAM + + VKGAY++ +LF+ I+AAR
Sbjct: 120 TETDTEVVAHLLAKYRRDGLGRREAMHAMLKRVKGAYALAVLFEDDPSTIMAART----G 175
Query: 185 PLVFGEGDGYYFASEDS-ALRMFGLETRDVLPGEVFVI 221
PL G G+G F D+ AL F E ++ G+ VI
Sbjct: 176 PLAIGHGNGEMFLGSDAIALAPFTNEITYLIDGDWAVI 213
>sp|P72720|GLMS_SYNY3 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434158|pir||S74575 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) -
Synechocystis sp. (strain PCC 6803)
>gi|1651800|dbj|BAA16727.1| (D90900)
L-glutamine:D-fructose-6-P amidotransferase
[Synechocystis sp.]
Length = 631
Score = 79.6 bits (193), Expect = 7e-14
Identities = 60/203 (29%), Positives = 100/203 (48%), Gaps = 17/203 (8%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGIS-VWNGRIRTIKGHGLVSEVFD--ENS 66
CGI G + ++ AV GL L++RG + AGI+ V G+I +++ G + + + EN
Sbjct: 2 CGIVGYIGTQTAVNILIEGLERLEYRGYDSAGIATVTEGKIESVRAKGKLFNLKEKLENH 61
Query: 67 LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
N S + IGH R++T G E +A+ NG + N+ LR + G +F
Sbjct: 62 SNF-SRLGIGHTRWATHGKPEEHNAHPHLDNQQRIAVVQNGIIENYQTLRDQLKEKGYQF 120
Query: 127 HSSVDTEVIGISFLNHYSQVKDE------FEAMRRVFEEVKGAYSILIL---FDGKIIAA 177
+S DTEVI I + + + EA+ + +++GA++I +L ++I A
Sbjct: 121 YSETDTEVIPILIADILKDLPSDDPDEALLEAIGKAVHQLEGAFAIAVLDAHCPEQLIVA 180
Query: 178 RDPVGFRPLVFGEGDGYYFASED 200
R PL+ G G G +F + D
Sbjct: 181 RQQA---PLILGFGQGEFFCASD 200
>sp|Q9WXZ5|GLMS_THEMA GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434166|pir||B72412 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) TM0148
[similarity] - Thermotoga maritima (strain MSB8)
>gi|4980641|gb|AAD35241.1|AE001700_5 (AE001700)
glucosamine--fructose-6-phosphate aminotransferase,
isomerizing [Thermotoga maritima]
Length = 606
Score = 78.8 bits (191), Expect = 1e-13
Identities = 71/245 (28%), Positives = 115/245 (45%), Gaps = 25/245 (10%)
Query: 11 CGIFGVSSEDA-VRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSEVFD--ENSL 67
CGI G+ E+ + L L++RG + AGI+ K G + + + + L
Sbjct: 2 CGIVGMVGENLKLEDLVTSLQKLEYRGYDSAGIAYLGDSFGVYKKKGRIDVLKNGLKQKL 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
N + I H R++T G +++ C E+A+ HNG + N+ +R E G F
Sbjct: 62 NDRFFVGIAHTRWATHGEPNDMNAHPHMDCKEEIAVVHNGIIENYREIREFLEQRGHVFS 121
Query: 128 SSVDTEVIGISFLNHYSQVKDEFE-----AMRRVFEEVKGAYSILILFDG---KIIAARD 179
S DTEVI V++EFE A+ + +++KGAY+I ++ I+AAR
Sbjct: 122 SETDTEVIA-------HLVEEEFEGDLLDAVLKAVKKLKGAYAIAVVHKNVPDTIVAARK 174
Query: 180 PVGFRPLVFGEGDGY-YFASEDSALRMFGLETRDVLPGEVFVI--DG-ESYESKVLAREK 235
PLV G G G AS+ + L F + + G+V V+ DG E Y + + +++
Sbjct: 175 G---SPLVAGIGSGVGILASDVTPLLRFTKDVVFLEDGDVMVLRKDGFEIYNTDGVKQQR 231
Query: 236 HAYCV 240
Y V
Sbjct: 232 RVYHV 236
>gb|AAF09884.1|AE001891_3 (AE001891) glucosamine--fructose-6-phosphate aminotransferase
(isomerizing) [Deinococcus radiodurans]
Length = 642
Score = 78.8 bits (191), Expect = 1e-13
Identities = 60/222 (27%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTI--KGHGLVSEVFDENSL 67
CGI G + A GL L++RG + AG++V +G + K L + D +
Sbjct: 38 CGIVGYIGPRQAQDVLLSGLSKLEYRGYDSAGVAVGDGACIAVRKKAGKLANLAGDLQAA 97
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
L+ + IGH R++T G ++ + + HNG + N++PL+ G F
Sbjct: 98 PLSGSFGIGHTRWATHGLPNDRNSHPHTTEDGRIVLVHNGIIENYLPLKEELLARGHTFK 157
Query: 128 SSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILI--LFDGKIIAARDPVGFRP 185
S D+EV+ Y + EA++ +V+GAY++++ + +I+AAR P
Sbjct: 158 SDTDSEVVAHLIEEAYQGNLE--EAVQAALAQVRGAYALVVTHVDHREIVAART---VSP 212
Query: 186 LVFGEGDGYYF-ASEDSALRMFGLETRDVLPGEVFVIDGESY 226
LV G G+G F AS+ AL + + ++ G++ ++ + Y
Sbjct: 213 LVMGVGEGEMFLASDVPALLAYTRQMVFLMDGDMVILSDDGY 254
>pir||A75536 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) DR0302 [similarity] - Deinococcus radiodurans
(strain R1)
Length = 606
Score = 78.8 bits (191), Expect = 1e-13
Identities = 60/222 (27%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTI--KGHGLVSEVFDENSL 67
CGI G + A GL L++RG + AG++V +G + K L + D +
Sbjct: 2 CGIVGYIGPRQAQDVLLSGLSKLEYRGYDSAGVAVGDGACIAVRKKAGKLANLAGDLQAA 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
L+ + IGH R++T G ++ + + HNG + N++PL+ G F
Sbjct: 62 PLSGSFGIGHTRWATHGLPNDRNSHPHTTEDGRIVLVHNGIIENYLPLKEELLARGHTFK 121
Query: 128 SSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILI--LFDGKIIAARDPVGFRP 185
S D+EV+ Y + EA++ +V+GAY++++ + +I+AAR P
Sbjct: 122 SDTDSEVVAHLIEEAYQGNLE--EAVQAALAQVRGAYALVVTHVDHREIVAART---VSP 176
Query: 186 LVFGEGDGYYF-ASEDSALRMFGLETRDVLPGEVFVIDGESY 226
LV G G+G F AS+ AL + + ++ G++ ++ + Y
Sbjct: 177 LVMGVGEGEMFLASDVPALLAYTRQMVFLMDGDMVILSDDGY 218
>pir||A82844 glucosamine--fructose-6-phosphate aminotransferase XF0141
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9104927|gb|AAF82954.1|AE003867_8 (AE003867)
glucosamine--fructose-6-phosphate aminotransferase
[Xylella fastidiosa]
Length = 609
Score = 78.0 bits (189), Expect = 2e-13
Identities = 63/223 (28%), Positives = 106/223 (47%), Gaps = 17/223 (7%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVW-NGRIRTIKGHGLVSEV-FDENSL 67
CGI G ++ D V GL L++RG + +GI+V +G IR ++ G V+E+
Sbjct: 2 CGIVGAIAGRDVVPVLIEGLKRLEYRGYDSSGIAVLESGSIRRVRRTGRVAEMAVAATQE 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
+++ IGH R++T G ++E G + + HNG + N R +G F
Sbjct: 62 GFTASLGIGHTRWATHGGVTEANAHPHVSHG--VVLVHNGIIENHEVQRERLSALGYVFQ 119
Query: 128 SSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDG---KIIAARDPVGFR 184
S DTEVI H Q D A++ + + G Y++ ++ + + + AR
Sbjct: 120 SQTDTEVIAHLIHYHMQQGDDLLGALQCAVKALTGIYALAVMSEAEPERFVCARMGC--- 176
Query: 185 PLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVIDGESYE 227
PL+ G GDG + + D + + TR V +F+ DG++ E
Sbjct: 177 PLLIGIGDGEHLVASDISAVI--QATRQV----IFLEDGDTAE 213
>sp|P08633|NODM_RHILV GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(GFAT) (NODULATION PROTEIN M) >gi|78031|pir||S01040
glutamine--fructose-6-phosphate transaminase
(isomerizing) (EC 2.6.1.16) - Rhizobium leguminosarum
bv. viciae plasmid pRL1JI >gi|46221|emb|CAA68626.1|
(Y00548) nodM [Rhizobium leguminosarum]
Length = 608
Score = 77.6 bits (188), Expect = 3e-13
Identities = 66/238 (27%), Positives = 108/238 (44%), Gaps = 17/238 (7%)
Query: 11 CGIFGVSSEDAV-RKTYYGLIALQHRGQEGAGIS-VWNGRIRTIKGHGLVSEVFDE-NSL 67
CGI G+ V + L L++RG + +G++ ++ G + + G + +
Sbjct: 2 CGIVGIVGHKPVSERLIEALGRLEYRGYDSSGVATIFEGELHRRRAEGKLGNLKTRLKEA 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
L+ + I H R++T G+ +E G +A+ HNG + NF L+ +G KF
Sbjct: 62 PLSGTVGIAHTRWATHGAPTECNAHPHFTDG--VAVVHNGIIENFSKLKDALAEVGTKFQ 119
Query: 128 SSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFD---GKIIAARDPVGFR 184
+ DTEVI EAM + + V+GA+++ ILF+ I+ AR+
Sbjct: 120 TDTDTEVIAHLLTKFRRDGMGCLEAMHAMLKCVEGAFALAILFEDDPATIMVARNG---P 176
Query: 185 PLVFGEGDGYYFASEDS-ALRMFGLETRDVLPGEVFVIDGES-----YESKVLAREKH 236
PLV G GDG F D+ AL F + + G+ V+ S E V+ R +H
Sbjct: 177 PLVIGHGDGEMFLGSDAIALAPFTNDITYLNDGDWAVVGKTSVQVFDIEGNVVTRPRH 234
>sp|Q9Z6U0|GLMS_CHLPN GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434170|pir||E72012 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) -
Chlamydophila pneumoniae (strain CWL029)
>gi|4377293|gb|AAD19104.1| (AE001677)
Glucosamine-Fructose-6-P Aminotransferase [Chlamydophila
pneumoniae CWL029]
Length = 609
Score = 75.7 bits (183), Expect = 1e-12
Identities = 67/227 (29%), Positives = 102/227 (44%), Gaps = 11/227 (4%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGIS-VWNGRIRTIKGHGLVSEV---FDEN 65
CGIFG + ++D V GL L++RG + AG++ V + K G V E+ F E
Sbjct: 2 CGIFGYLGNQDGVSIVLEGLAKLEYRGYDSAGLAAVVEQELFIRKTVGRVQELSNLFQER 61
Query: 66 SLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIK 125
+ AS IGH R++T G +E+ G A+ HNG + NF LRR GI
Sbjct: 62 EIPTAS--VIGHTRWATHGVPTEINAHPHVDEGRSCAVVHNGIIENFKELRRELTAQGIS 119
Query: 126 FHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFRP 185
F S D+E+I F +Y + +D + + +++G+ + ++ P
Sbjct: 120 FASDTDSEIIVQLFSLYYQESQDLVFSFCQTLAQLRGSVACALIHKDHPHTILCASQESP 179
Query: 186 LVFGEGDGYYFASEDSALRMFGLETR--DVLPGEVFVIDGESYESKV 230
L+ G G F + DS R F TR L F I + E +V
Sbjct: 180 LILGLGKEETFIASDS--RAFFKYTRHSQALASGEFAIVSQGKEPEV 224
>pir||B81528 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) CP0892 [similarity] - Chlamydophila pneumoniae
(strain AR39) >gi|7189804|gb|AAF38679.1| (AE002247)
glucosamine--fructose-6-phosphate aminotransferase
(isomerizing) [Chlamydophila pneumoniae AR39]
>gi|8979342|dbj|BAA99176.1| (AP002548)
glucosamine-fructose-6-P aminotransferase [Chlamydophila
pneumoniae J138]
Length = 609
Score = 75.7 bits (183), Expect = 1e-12
Identities = 67/227 (29%), Positives = 102/227 (44%), Gaps = 11/227 (4%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGIS-VWNGRIRTIKGHGLVSEV---FDEN 65
CGIFG + ++D V GL L++RG + AG++ V + K G V E+ F E
Sbjct: 2 CGIFGYLGNQDGVSIVLEGLAKLEYRGYDSAGLAAVVEQELFIRKTVGRVQELSNLFQER 61
Query: 66 SLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIK 125
+ AS IGH R++T G +E+ G A+ HNG + NF LRR GI
Sbjct: 62 EIPTAS--VIGHTRWATHGVPTEINAHPHVDEGRSCAVVHNGIIENFKELRRELTAQGIS 119
Query: 126 FHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFRP 185
F S D+E+I F +Y + +D + + +++G+ + ++ P
Sbjct: 120 FASDTDSEIIVQLFSLYYQESQDLVFSFCQTLAQLRGSVACALIHKDHPHTILCASQESP 179
Query: 186 LVFGEGDGYYFASEDSALRMFGLETR--DVLPGEVFVIDGESYESKV 230
L+ G G F + DS R F TR L F I + E +V
Sbjct: 180 LILGLGKEETFIASDS--RAFFKYTRHSQALASGEFAIVSQGKEPEV 224
>sp|O68280|GLMS_NOSS9 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|3169799|gb|AAC17973.1| (AF028734)
glutamine-fructose-6-P-aminotransferase; NodM [Nostoc
PCC9229]
Length = 627
Score = 74.9 bits (181), Expect = 2e-12
Identities = 63/219 (28%), Positives = 101/219 (45%), Gaps = 18/219 (8%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGIS-VWNGRIRTIKGHGLVSEVFDENSL- 67
CGI G + ++ A GL L++RG + AGI+ VW G I ++ G + + + L
Sbjct: 2 CGIVGYIGTQAATDILLAGLEKLEYRGYDSAGIATVWEGEINCVRAKGKLHNLRSKLELI 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
+ I IGH R++T G E +A+ NG + N+ LR + G F
Sbjct: 62 ETPAQIGIGHTRWATHGKPEEYNAHPHVDTAMPVAV-QNGIIENYRELREELKAKGHVFR 120
Query: 128 SSVDTEVIG------ISFLNHYSQVKDEFEAMRRVFEEVKGAYSILIL---FDGKIIAAR 178
S DTEVI + + S D EA+ + ++GA+++ ++ + ++I R
Sbjct: 121 SETDTEVIPHLIAEILKNFSASSSSSDFLEAVSQAVNRLEGAFALAVVCADYPDELIVVR 180
Query: 179 DPVGFRPLVFGEGDGYYFASEDSALRMFGLETRDVLPGE 217
PLV G G G +F + D+ + TR VLP E
Sbjct: 181 QQA---PLVIGFGQGEFFCASDTPAIV--AYTRAVLPLE 214
>sp|P39754|GLMS_BACSU GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434161|pir||B69633 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) glmS -
Bacillus subtilis >gi|726480|gb|AAA64224.1| (U21932)
L-glutamine-D-fructose-6-phosphate amidotransferase
[Bacillus subtilis] >gi|2632445|emb|CAB11954.1| (Z99104)
L-glutamine-D-fructose-6-phosphate amidotransferase
[Bacillus subtilis] >gi|2632463|emb|CAB11971.1| (Z99105)
L-glutamine-D-fructose-6-phosphate amidotransferase
[Bacillus subtilis] >gi|3599596|dbj|BAA33071.1|
(AB006424) L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDO
TRANSFERASE [Bacillus subtilis]
Length = 600
Score = 73.7 bits (178), Expect = 4e-12
Identities = 78/324 (24%), Positives = 141/324 (43%), Gaps = 35/324 (10%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEVFDENSLN 68
CGI G + DA GL L++RG + AGI+V N + I K G ++++ + N
Sbjct: 2 CGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEQGIHVFKEKGRIADLREVVDAN 61
Query: 69 LASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFHS 128
+ + IGH R++T G S + + + HNG + N++ L++ Y ++ S
Sbjct: 62 VEAKAGIGHTRWATHGEPSYLNAHPHQSALGRFTLVHNGVIENYVQLKQEYL-QDVELKS 120
Query: 129 SVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDG----KIIAARDPVGFR 184
DTEV+ + + EA R+ +KG+Y+I LFD I A++
Sbjct: 121 DTDTEVVVQVIEQFVNGGLETEEAFRKTLTLLKGSYAI-ALFDNDNRETIFVAKNK---S 176
Query: 185 PLVFGEGDGY-YFASEDSALRMFGLETRDVLPGEVFVIDGESYESKVLAREKHAYCVFEY 243
PL+ G GD + AS+ A+ E +++ E+ ++ + +V+ + +
Sbjct: 177 PLLVGLGDTFNVVASDAMAMLQVTNEYVELMDKEMVIVT----DDQVVIKNLDGDVITRA 232
Query: 244 IYFARPDST-----------LNGINVYCARYRMGVELARESPAE----GDVVIAVPDSGR 288
Y A D++ L + R ++ ++ + GD+ AV ++ R
Sbjct: 233 SYIAELDASDIEKGTYPHYMLKETDEQPVVMRKIIQTYQDENGKLSVPGDIAAAVAEADR 292
Query: 289 TAALGFAHESGIPYMEGLIKNRYI 312
+G G Y GL+ +YI
Sbjct: 293 IYIIG----CGTSYHAGLVGKQYI 312
>sp|O06253|GLMS_MYCTU GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434157|pir||B70976 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) -
Mycobacterium tuberculosis (strain H37RV)
>gi|2104357|emb|CAB08685.1| (Z95389) glmS [Mycobacterium
tuberculosis] >gi|2388656|gb|AAB69988.1| (AF002814)
L-glutamine:D-fructose-6-phosphate amidotransferase
[Mycobacterium tuberculosis]
Length = 624
Score = 73.4 bits (177), Expect = 5e-12
Identities = 57/204 (27%), Positives = 95/204 (45%), Gaps = 15/204 (7%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHG-----LVSEVFDE 64
CGI G V A L +++RG + +GI++ +G T++ L V +
Sbjct: 2 CGIVGYVGRRPAYVVVMDALRRMEYRGYDSSGIALVDGGTLTVRRRAGRLANLEEAVAEM 61
Query: 65 NSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
S L+ +GH R++T G ++ R ++A+ HNG + NF LRR E G+
Sbjct: 62 PSTALSGTTGLGHTRWATHGRPTDRNAHPHRDAAGKIAVVHNGIIENFAVLRRELETAGV 121
Query: 125 KFHSSVDTEVIG--ISFLNHYSQVKDEF-EAMRRVFEEVKGAYSILIL---FDGKIIAAR 178
+F S DTEV ++ + + D+F ++ V ++G ++++ G ++AAR
Sbjct: 122 EFASDTDTEVAAHLVARAYRHGETADDFVGSVLAVLRRLEGHFTLVFANADDPGTLVAAR 181
Query: 179 DPVGFRPLVFGEGDGYYFASEDSA 202
PLV G GD F D A
Sbjct: 182 RST---PLVLGIGDNEMFVGSDVA 202
>emb|CAA04007.1| (AJ000333) glmS [Mycobacterium tuberculosis]
Length = 813
Score = 73.4 bits (177), Expect = 5e-12
Identities = 57/204 (27%), Positives = 95/204 (45%), Gaps = 15/204 (7%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHG-----LVSEVFDE 64
CGI G V A L +++RG + +GI++ +G T++ L V +
Sbjct: 191 CGIVGYVGRRPAYVVVMDALRRMEYRGYDSSGIALVDGGTLTVRRRAGRLANLEEAVAEM 250
Query: 65 NSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
S L+ +GH R++T G ++ R ++A+ HNG + NF LRR E G+
Sbjct: 251 PSTALSGTTGLGHTRWATHGRPTDRNAHPHRDAAGKIAVVHNGIIENFAVLRRELETAGV 310
Query: 125 KFHSSVDTEVIG--ISFLNHYSQVKDEF-EAMRRVFEEVKGAYSILIL---FDGKIIAAR 178
+F S DTEV ++ + + D+F ++ V ++G ++++ G ++AAR
Sbjct: 311 EFASDTDTEVAAHLVARAYRHGETADDFVGSVLAVLRRLEGHFTLVFANADDPGTLVAAR 370
Query: 179 DPVGFRPLVFGEGDGYYFASEDSA 202
PLV G GD F D A
Sbjct: 371 RST---PLVLGIGDNEMFVGSDVA 391
>sp|O26060|GLMS_HELPY GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434160|pir||D64711 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) - Helicobacter
pylori (strain 26695) >gi|2314711|gb|AAD08570.1|
(AE000651) glucosamine fructose-6-phosphate
aminotransferase (isomerizing) (glmS) [Helicobacter
pylori 26695]
Length = 597
Score = 73.4 bits (177), Expect = 5e-12
Identities = 61/200 (30%), Positives = 91/200 (45%), Gaps = 11/200 (5%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVW-NGRIRTIKGHGLVSEVFDE--NS 66
CGI G + + GL L++RG + AG++V N R+ K G + + E N
Sbjct: 2 CGIVGYIGDSEKKSVLLEGLKELEYRGYDSAGLAVLSNDRLEVFKTQGKLENLKLELKNK 61
Query: 67 LNLASNIAIGHVRYSTSG--SLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
L ++I H R++T G S + P LA+ HNG + N+ L++ E G
Sbjct: 62 EFLDFGVSIAHTRWATHGKPSSANAHPHFTE----NLALVHNGIIENYASLKKELENKGH 117
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFR 184
F S DTEVI D +A + +KG+Y+IL+L +
Sbjct: 118 AFLSQTDTEVIAHLLEETLKSESDLLKAFEKSISLLKGSYAILMLHKRAKESLFYAKSSS 177
Query: 185 PLVFGEG-DGYYFASEDSAL 203
PLV G+G +G +FAS S L
Sbjct: 178 PLVVGKGKEGVFFASSLSVL 197
>sp|P40831|GLMS_MYCLE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|2145872|pir||S72993 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) -
Mycobacterium leprae >gi|467125|gb|AAA17307.1| (U00020)
glmS; L-Glucosamine:D-fructose-6-phosphate
aminotransferase; B229_C3_238 [Mycobacterium leprae]
Length = 625
Score = 73.0 bits (176), Expect = 7e-12
Identities = 61/212 (28%), Positives = 97/212 (44%), Gaps = 29/212 (13%)
Query: 6 GMREKCGIFGVSSEDAVRKTYYGLIALQHRGQEGAGISVWNG---------RIRTIKGHG 56
G R CG+ DA+R+ +++RG + +GI++ NG R R +
Sbjct: 9 GQRPACGVV----MDALRR-------MEYRGYDSSGIALINGSAKSGNLTVRRRAGRLSN 57
Query: 57 LVSEVFDENSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLR 116
L S + + +LA N+ +GH+R++T G ++ R ++A+ HNG + NF LR
Sbjct: 58 LESVLAEMVPASLAGNVGLGHIRWATHGRPTDRNAHPHRDATGKIAVVHNGIIENFPSLR 117
Query: 117 RLYEGMGIKFHSSVDTEVIGISFLNHY---SQVKDEFEAMRRVFEEVKGAYSILIL---F 170
E G++F S DTEV Y D ++ V ++G ++++
Sbjct: 118 HELEIAGVEFVSDTDTEVAVHLVAQAYCAGETAGDFVGSVLAVLRRLQGHFTLVFANADE 177
Query: 171 DGKIIAARDPVGFRPLVFGEGDGYYFASEDSA 202
G I+AAR PLV G GDG F D A
Sbjct: 178 PGTIVAARRST---PLVLGIGDGEMFVGSDVA 206
>emb|CAA25785.1| (X01631) gluS protein [Escherichia coli]
Length = 609
Score = 72.2 bits (174), Expect = 1e-11
Identities = 60/199 (30%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNG-----RIRTIKGHGLVSEVFDE 64
CGI G ++ D GL L++RG + AG++V + R+R + ++++ +E
Sbjct: 2 CGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEE 61
Query: 65 NSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
+ L+ + IA H R++T G SEV + + HNG + N PLR + G
Sbjct: 62 HPLHGGTGIA--HTRWATHGEPSEVNAHPH--VSEHIVVVHNGIIENHEPLREELKARGY 117
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILIL---FDGKIIAARDPV 181
F S DTEVI Q EA+ R +++GAY +I+ ++AAR
Sbjct: 118 TFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSG- 176
Query: 182 GFRPLVFGEGDGYYFASED 200
PLV G G G F + D
Sbjct: 177 --SPLVIGLGMGENFIASD 193
>gb|AAA62080.1| (L10328) glutamine amidotransferase [Escherichia coli]
Length = 609
Score = 72.2 bits (174), Expect = 1e-11
Identities = 60/199 (30%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNG-----RIRTIKGHGLVSEVFDE 64
CGI G ++ D GL L++RG + AG++V + R+R + ++++ +E
Sbjct: 2 CGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEE 61
Query: 65 NSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
+ L+ + IA H R++T G SEV + + HNG + N PLR + G
Sbjct: 62 HPLHGGTGIA--HTRWATHGEPSEVNAHPH--VSEHIVVVHNGIIENHEPLREELKARGY 117
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILIL---FDGKIIAARDPV 181
F S DTEVI Q EA+ R +++GAY +I+ ++AAR
Sbjct: 118 TFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSG- 176
Query: 182 GFRPLVFGEGDGYYFASED 200
PLV G G G F + D
Sbjct: 177 --SPLVIGLGMGENFIASD 193
>sp|P17169|GLMS_ECOLI GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7427965|pir||XNECGM glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) - Escherichia
coli >gi|1790167|gb|AAC76752.1| (AE000450)
L-glutamine:D-fructose-6-phosphate aminotransferase
[Escherichia coli K12]
Length = 609
Score = 72.2 bits (174), Expect = 1e-11
Identities = 60/199 (30%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNG-----RIRTIKGHGLVSEVFDE 64
CGI G ++ D GL L++RG + AG++V + R+R + ++++ +E
Sbjct: 2 CGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEE 61
Query: 65 NSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
+ L+ + IA H R++T G SEV + + HNG + N PLR + G
Sbjct: 62 HPLHGGTGIA--HTRWATHGEPSEVNAHPH--VSEHIVVVHNGIIENHEPLREELKARGY 117
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILIL---FDGKIIAARDPV 181
F S DTEVI Q EA+ R +++GAY +I+ ++AAR
Sbjct: 118 TFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSG- 176
Query: 182 GFRPLVFGEGDGYYFASED 200
PLV G G G F + D
Sbjct: 177 --SPLVIGLGMGENFIASD 193
>pdb|1GDO|B Chain B, Glutaminase Domain Of Glucosamine 6-Phosphate Synthase
Complexed With Glutamate >gi|1827667|pdb|1GDO|D Chain D,
Glutaminase Domain Of Glucosamine 6-Phosphate Synthase
Complexed With Glutamate >gi|1827658|pdb|1GMS|C Chain C,
Glutaminase Domain Of Glucosamine 6-Phosphate Synthase
Complexed With L-Glu Hydroxamate >gi|1827660|pdb|1GMS|G
Chain G, Glutaminase Domain Of Glucosamine 6-Phosphate
Synthase Complexed With L-Glu Hydroxamate
>gi|1827661|pdb|1GDO|A Chain A, Glutaminase Domain Of
Glucosamine 6-Phosphate Synthase Complexed With
Glutamate >gi|1827665|pdb|1GDO|C Chain C, Glutaminase
Domain Of Glucosamine 6-Phosphate Synthase Complexed
With Glutamate >gi|1827657|pdb|1GMS|A Chain A,
Glutaminase Domain Of Glucosamine 6-Phosphate Synthase
Complexed With L-Glu Hydroxamate >gi|1827659|pdb|1GMS|E
Chain E, Glutaminase Domain Of Glucosamine 6-Phosphate
Synthase Complexed With L-Glu Hydroxamate
Length = 240
Score = 72.2 bits (174), Expect = 1e-11
Identities = 60/199 (30%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNG-----RIRTIKGHGLVSEVFDE 64
CGI G ++ D GL L++RG + AG++V + R+R + ++++ +E
Sbjct: 1 CGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEE 60
Query: 65 NSLNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
+ L+ + IA H R++T G SEV + + HNG + N PLR + G
Sbjct: 61 HPLHGGTGIA--HTRWATHGEPSEVNAHPH--VSEHIVVVHNGIIENHEPLREELKARGY 116
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILIL---FDGKIIAARDPV 181
F S DTEVI Q EA+ R +++GAY +I+ ++AAR
Sbjct: 117 TFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSG- 175
Query: 182 GFRPLVFGEGDGYYFASED 200
PLV G G G F + D
Sbjct: 176 --SPLVIGLGMGENFIASD 192
>sp|O66648|GLMS_AQUAE GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434169|pir||D70327 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) - Aquifex
aeolicus >gi|2982997|gb|AAC06609.1| (AE000683)
glucosamine-fructose-6-phosphate aminotransferase
[Aquifex aeolicus]
Length = 592
Score = 72.2 bits (174), Expect = 1e-11
Identities = 52/196 (26%), Positives = 93/196 (46%), Gaps = 11/196 (5%)
Query: 11 CGIFGVSSEDAVRKTYYGLIA-LQHRGQEGAGIS-VWNGRIRTIKGHGLVSEVFDEN-SL 67
CGI G D G + L++RG + AG++ + +G++ K G + E+
Sbjct: 2 CGIVGYVGRDLALPIVLGALERLEYRGYDSAGVALIEDGKLIVEKKKGKIRELVKALWGK 61
Query: 68 NLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFH 127
+ + IGH R++T G ++ E A+ HNG + N++ L+ + G+KF
Sbjct: 62 DYKAKTGIGHTRWATHGKPTDENAHPHTDEKGEFAVVHNGIIENYLELKEELKKEGVKFR 121
Query: 128 SSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILF---DGKIIAARDPVGFR 184
S DTEVI +Y D EA+ + +++KGA++ ++ ++I +
Sbjct: 122 SETDTEVIAHLIAKNYR--GDLLEAVLKTVKKLKGAFAFAVITVHEPNRLIGVKQG---S 176
Query: 185 PLVFGEGDGYYFASED 200
PL+ G G+G F + D
Sbjct: 177 PLIVGLGEGENFLASD 192
>sp|Q9ZJ94|GLMS_HELPJ GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]
(HEXOSEPHOSPHATE AMINOTRANSFERASE)
(D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE) (GFAT)
(L-GLUTAMINE-D-FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE)
(GLUCOSAMINE-6-PHOSPHATE SYNTHASE)
>gi|7434159|pir||H71809 glutamine--fructose-6-phosphate
transaminase (isomerizing) (EC 2.6.1.16) - Helicobacter
pylori (strain J99) >gi|4156041|gb|AAD06999.1|
(AE001564) glutamine fructose-6-phosphate
aminotransferase [Helicobacter pylori J99]
Length = 597
Score = 71.4 bits (172), Expect = 2e-11
Identities = 59/200 (29%), Positives = 91/200 (45%), Gaps = 11/200 (5%)
Query: 11 CGIFGVSSEDAVRKTYY-GLIALQHRGQEGAGISVWNG-RIRTIKGHGLVSEVFDE--NS 66
CGI G + + GL L++RG + AG++V + R+ K G + + E N
Sbjct: 2 CGIVGYIGDSEKKSILLEGLKELEYRGYDSAGLAVLSANRLEVFKTQGKLENLRTELKNK 61
Query: 67 LNLASNIAIGHVRYSTSG--SLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGI 124
L ++I H R++T G S + P LA+ HNG + N+ L++ E G
Sbjct: 62 EFLNFGVSIAHTRWATHGKPSSANAHPHFTE----NLALVHNGIIENYASLKKELENKGH 117
Query: 125 KFHSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFR 184
F S DTEVI D +A + +KG+Y+IL+L +
Sbjct: 118 AFLSQTDTEVIAHLLEETLKSEGDLLKAFEKSISLLKGSYAILMLHKRAKESLFYAKSSS 177
Query: 185 PLVFGEG-DGYYFASEDSAL 203
PL+ G+G +G +FAS S L
Sbjct: 178 PLIVGKGKEGVFFASSLSVL 197
>dbj|BAB03987.1| (AP001507) L-glutamine-D-fructose-6-phosphate amidotransferase
[Bacillus halodurans]
Length = 600
Score = 71.4 bits (172), Expect = 2e-11
Identities = 59/225 (26%), Positives = 99/225 (43%), Gaps = 6/225 (2%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNGR-IRTIKGHGLVSEVFDENSLN 68
CGI G + +EDA GL L++RG + AGI+V + K G ++ + +
Sbjct: 2 CGIVGYIGTEDAKEILLKGLEKLEYRGYDSAGIAVATEEGVHIFKEKGRIATLREVVDQG 61
Query: 69 LASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFHS 128
+ S + IGH R++T G S+V + I HNG + N+ L+R Y + S
Sbjct: 62 VKSTVGIGHTRWATHGEPSKVNAHPHQSESSRFTIVHNGVIENYEQLKRDYL-QAVTLQS 120
Query: 129 SVDTEVIGISFLNHYSQVKDEFE-AMRRVFEEVKGAYSILILFDGKIIAARDPVGFRPLV 187
DTEV+ + + + E A R +KG+Y+I +L PL+
Sbjct: 121 DTDTEVV-VQLVERFVHEGQSVEAAFRHTLSLLKGSYAIALLDKKDTDTIYVGKNKSPLL 179
Query: 188 FGEGDGY-YFASEDSALRMFGLETRDVLPGEVFVIDGESYESKVL 231
G DG AS+ A+ + +++ E+ ++ + K L
Sbjct: 180 VGVQDGVNVVASDAMAMLQVTDQFLEIMDEEIVIVTKDDVTIKTL 224
>gb|AAG18649.1| (AE004970) glutamine-fructose-6-phosphate transaminase; GlmS
[Halobacterium sp. NRC-1]
Length = 601
Score = 71.4 bits (172), Expect = 2e-11
Identities = 57/196 (29%), Positives = 90/196 (45%), Gaps = 12/196 (6%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSEVFDENSLNL 69
CGI G + ++ R + GL L++RG + AGI++ G ++ H EV D +
Sbjct: 2 CGITGYIGTDPTGRIVHEGLQNLEYRGYDSAGIALAGGGSLSV--HKTGGEVGDLPVPSR 59
Query: 70 ASNI-AIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKFHS 128
IGH R+ST G + C ++A+ HNG + N+ L + FHS
Sbjct: 60 EDGTRGIGHTRWSTHGEPTRENAHPHTDCTGDVAVVHNGIIENYAALADELRADHV-FHS 118
Query: 129 SVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILIL---FDGKIIAARDPVGFRP 185
DTEV+ H + A++R E + G+Y++ I DG ++A D P
Sbjct: 119 DTDTEVVPHLIETHLADGVSLLTAVQRTTERLTGSYALAITAAGHDGIVVARSD----SP 174
Query: 186 LVFGEGDGYYFASEDS 201
L+ G GD F + D+
Sbjct: 175 LLLGHGDTGTFVASDA 190
>pir||C81281 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC
2.6.1.16) Cj1366c [similarity] - Campylobacter jejuni
(strain NCTC 11168) >gi|6968800|emb|CAB73793.1|
(AL139078) glucosamine--fructose-6-phosphate
aminotransferase (isomerizing) [Campylobacter jejuni]
Length = 598
Score = 71.0 bits (171), Expect = 3e-11
Identities = 55/205 (26%), Positives = 99/205 (47%), Gaps = 21/205 (10%)
Query: 11 CGIFG-VSSEDAVRKTYYGLIALQHRGQEGAGISVWN-GRIRTIKGHGLVSEVFDE--NS 66
CGI G + + + + GL L++RG + AG++V G + K G + + ++ +
Sbjct: 2 CGIVGYIGNNEKKQIILNGLKELEYRGYDSAGMAVMQEGELSFFKAVGKLENLANKCTDF 61
Query: 67 LNLASNIAIGHVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
+ AIGH R++T G +E+ G + HNG + N+ ++ E G+ F
Sbjct: 62 ESQGYGFAIGHTRWATHGKPTEINAHPH--LGQYSCVIHNGIIENYKEIKDKLEKEGVSF 119
Query: 127 HSSVDTEVIGISFLNHYSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDP------ 180
S DTEVI + Y++ FEA ++ +E++GA++ L ++ +DP
Sbjct: 120 LSQTDTEVI-VQLFEFYARNLGVFEAWQKTIKELRGAFATL------LVTKKDPNHVYFA 172
Query: 181 VGFRPLVFGEGDG--YYFASEDSAL 203
PL+ G+ +YF+S D+ L
Sbjct: 173 KNAAPLIIGKNANKEWYFSSGDAPL 197
>pir||G71050 asparagine synthase (glutamine-hydrolyzing) (EC 6.3.5.4) PH1102
[similarity] - Pyrococcus horikoshii
>gi|3257518|dbj|BAA30201.1| (AP000005) 480aa long
hypothetical asparagine synthetase [Pyrococcus
horikoshii]
Length = 480
Score = 70.2 bits (169), Expect = 4e-11
Identities = 60/217 (27%), Positives = 96/217 (43%), Gaps = 32/217 (14%)
Query: 12 GIFGVSSEDAVRKTYYGLIALQHRGQEGAGISVWNGRIRTIKGHGLVSEVFDENSLNLAS 71
G F + +++ +R G +HRG + G VW+ R EV + +
Sbjct: 6 GGFKLYTDEIIRIIELG----KHRGPDSFG--VWSER-----------EVIKSSDFSALE 48
Query: 72 NIAIG-----HVRYSTSGSLSEVQPLEVRCCGYELAIAHNGTLTNFIPLRRLYEGMGIKF 126
+ G R + +GS QP E+A+ HNG + N LR GI F
Sbjct: 49 EVKGGDKVLIQCRLAMTGSKEYTQPFY-----NEIALVHNGEIYNHEKLRAYLVERGISF 103
Query: 127 HSSVDTEVIGISFLNH--YSQVKDEFEAMRRVFEEVKGAYSILILFDGKIIAARDPVGFR 184
S VD+EVI + L + + + + A++++ ++G Y++ ++GK RDP+G R
Sbjct: 104 ESDVDSEVI-LRLLEYLLFDRNLSPWNAIKKLMWMLRGDYAVAFHYNGKFYLFRDPLGIR 162
Query: 185 PLVFGEGDGYYFASEDSALRMFGLETRDVLPGEVFVI 221
PL + +F SE L G E V+PGE I
Sbjct: 163 PLYYSSQG--HFGSEKKVLWGLGEEATPVMPGEAVEI 197
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.322 0.141 0.416
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 165711484
Number of Sequences: 2977
Number of extensions: 7069106
Number of successful extensions: 14299
Number of sequences better than 1.0e-10: 114
Number of HSP's better than 0.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 13716
Number of HSP's gapped (non-prelim): 123
length of query: 447
length of database: 189,106,746
effective HSP length: 54
effective length of query: 393
effective length of database: 156,788,448
effective search space: 61617860064
effective search space used: 61617860064
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 166 (69.1 bits)