BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0154 (tldD) DE:TLDD PROTEIN (452 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Ors... 908 0.0 pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii >gi|3256... 689 0.0 sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir... 350 2e-95 sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|... 321 1e-86 pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii 321 1e-86 pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (st... 290 2e-77 gi|11498263 conserved hypothetical protein [Archaeoglobus fulgid... 290 2e-77 pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii ... 281 1e-74 pir||G75033 hypothetical protein PAB1547 - Pyrococcus abyssi (st... 260 3e-68 pir||D71135 tldD-related protein PH0848 - Pyrococcus horikoshii ... 254 2e-66 pir||D72762 hypothetical protein APE0089 - Aeropyrum pernix (str... 252 6e-66 gb|AAK40965.1| Zn-dependent protease, tldD protein homolog, puta... 238 1e-61 emb|CAB57642.1| (Y18930) hypothetical protein [Sulfolobus solfat... 238 1e-61 sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD p... 231 1e-59 pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (gr... 223 3e-57 sp|P73754|Y863_SYNY3 HYPOTHETICAL 50.4 KD PROTEIN SLR0863 >gi|74... 220 2e-56 gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum] 219 5e-56 pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07... 217 2e-55 pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa ... 215 8e-55 sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13... 215 8e-55 pir||D72342 tldD protein - Thermotoga maritima (strain MSB8) >gi... 209 5e-53 pir||D83086 conserved hypothetical protein PA4474 [imported] - P... 205 9e-52 sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG 199 7e-50 pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria ... 191 1e-47 pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningit... 191 1e-47 emb|CAC11942.1| (AL445065) conserved hypothetical protein [Therm... 185 9e-46 gb|AAK41402.1| Conserved hypothetical protein [Sulfolobus solfat... 182 6e-45 pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment) 173 5e-42 dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity... 158 1e-37 sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|74... 153 4e-36 pir||E70461 pmbA protein - Aquifex aeolicus >gi|2984159|gb|AAC07... 144 2e-33 pir||B83330 hypothetical protein PA2529 [imported] - Pseudomonas... 136 4e-31 pir||E72342 pmbA-related protein - Thermotoga maritima (strain M... 133 4e-30 pir||D70703 tldD homolog Rv2315c - Mycobacterium tuberculosis (s... 125 7e-28 pir||T36780 hypothetical protein SCI28.10 - Streptomyces coelico... 116 6e-25 gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis] 113 4e-24 pir||B71249 hypothetical protein PH0249 - Pyrococcus horikoshii ... 111 1e-23 pir||B69009 conserved hypothetical protein MTH1070 - Methanobact... 110 3e-23 sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||... 102 6e-21 pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus aby... 100 3e-20 pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (st... 99 9e-20 pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (gr... 97 5e-19 sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C6418... 96 6e-19 pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aerugin... 94 3e-18 sp|P57191|PMBA_BUCAI PMBA PROTEIN HOMOLOG >gi|10038774|dbj|BAB12... 93 7e-18 pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii ... 89 8e-17 pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (st... 88 2e-16 pir||D81151 pmbA protein NMB0839 [imported] - Neisseria meningit... 84 3e-15 pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii ... 83 5e-15 pir||H81869 hypothetical protein NMA1048 [imported] - Neisseria ... 81 3e-14 pir||S75708 hypothetical protein sll0887 - Synechocystis sp. (st... 80 4e-14 dbj|BAB05756.1| (AP001514) unknown conserved protein in others [... 80 7e-14 pir||B75180 antibiotic/peptide maturation related protein PAB195... 77 4e-13 pir||I64173 hypothetical protein HI1653 - Haemophilus influenzae... 76 6e-13 sp|Q57684|Y231_METJA HYPOTHETICAL PROTEIN MJ0231 >gi|2128001|pir... 76 1e-12 emb|CAC11943.1| (AL445065) conserved hypothetical protein [Therm... 75 2e-12 gi|11498264 antibiotic maturation protein (pmbA) [Archaeoglobus ... 75 2e-12 gb|AAF65318.1|AF234655_1 (AF234655) LmbIH [Streptomyces lincolne... 69 8e-11 >pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Orsay) >gi|5457661|emb|CAB49152.1| (AJ248283) TLDD PROTEIN [Pyrococcus abyssi] Length = 452 Score = 908 bits (2320), Expect = 0.0 Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 1 MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWGF 60 MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWGF Sbjct: 1 MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWGF 60 Query: 61 ASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL 120 ASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL Sbjct: 61 ASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL 120 Query: 121 EVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW 180 EVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW Sbjct: 121 EVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW 180 Query: 181 KSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG 240 KSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG Sbjct: 181 KSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG 240 Query: 241 HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD 300 HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD Sbjct: 241 HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD 300 Query: 301 GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV 360 GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV Sbjct: 301 GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV 360 Query: 361 YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420 YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK Sbjct: 361 YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420 Query: 421 IEFPGFCGKGQWVPVDDGGPHVLVKAIVGGRE 452 IEFPGFCGKGQWVPVDDGGPHVLVKAIVGGRE Sbjct: 421 IEFPGFCGKGQWVPVDDGGPHVLVKAIVGGRE 452 >pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii >gi|3256635|dbj|BAA29318.1| (AP000001) 504aa long hypothetical tldd protein [Pyrococcus horikoshii] Length = 504 Score = 689 bits (1759), Expect = 0.0 Identities = 321/454 (70%), Positives = 387/454 (84%), Gaps = 2/454 (0%) Query: 1 MIDELRNLIEKYSN--EVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW 58 MIDE+ ++EKYS+ E+KFMDIR E+ YTE T+ENGKVE +E+N E G+GVRVLINGW Sbjct: 51 MIDEILKVLEKYSSSSEIKFMDIRMESIEYTELTIENGKVENLENNGERGVGVRVLINGW 110 Query: 59 GFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKL 118 GFASTNDL+K+E+ +K AIK+AKVS +Y +P+E +KQ D+DLEEK KL Sbjct: 111 GFASTNDLTKIEEIVKTAIKMAKVSRISTSVYTRDPIEDNVEVKQGIKLKDIDLEEKVKL 170 Query: 119 GLEVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT 178 G+EV M++R+ IKT +FSYSD + +K+YL+SEGS+IE+ VPR+Y S+S+VA+ + MQT Sbjct: 171 GVEVNNMLKRENIKTRKFSYSDIIVKKLYLSSEGSIIESTVPRVYLSISSVAKFSGKMQT 230 Query: 179 YWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEA 238 YWKSFGGT GWE+VE +DF +WANF+S KA+SLLSARSPPSGEM +IMDPELAGVFIHEA Sbjct: 231 YWKSFGGTGGWEIVEKIDFEHWANFVSKKAVSLLSARSPPSGEMQVIMDPELAGVFIHEA 290 Query: 239 LGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298 LGHA EAD+V+Q ESIL+GM+GK+I EELTV+DDPTLPGKFGSY+YDDEG+PGKRVEII Sbjct: 291 LGHASEADAVKQEESILAGMLGKRIAVEELTVVDDPTLPGKFGSYIYDDEGIPGKRVEII 350 Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358 +DGVL+NYLNDRETS LNL PNGHGRAQSY+HVPLVRMSNTYI PG+W EE+ +EVKF Sbjct: 351 RDGVLVNYLNDRETSSLLNLEPNGHGRAQSYSHVPLVRMSNTYIEPGDWRFEEILDEVKF 410 Query: 359 GVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418 GVYMIGDKGGQVD+A+G+FMF AKEGY+++ GEIK +RDV +SGNIL L+EIKA+G D Sbjct: 411 GVYMIGDKGGQVDVASGNFMFAAKEGYLVENGEIKGHLRDVALSGNILSALREIKAIGND 470 Query: 419 LKIEFPGFCGKGQWVPVDDGGPHVLVKAIVGGRE 452 LKIEFPGFCGKGQWVPVDDGGPHVL KAIVGG E Sbjct: 471 LKIEFPGFCGKGQWVPVDDGGPHVLTKAIVGGLE 504 >sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir||C69214 zinc metalloproteinase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621948|gb|AAB85354.1| (AE000862) zinc metalloproteinase [Methanobacterium thermoautotrophicum] Length = 454 Score = 350 bits (889), Expect = 2e-95 Identities = 193/451 (42%), Positives = 277/451 (60%), Gaps = 6/451 (1%) Query: 3 DELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFA 61 D L +++ + V++ DIR + + +++GK++ V+S G +RVL NG WGFA Sbjct: 6 DYLGSILMDIEDRVEYADIRAGTSRTSSILMKDGKLQEVKSGRASGFRIRVLRNGSWGFA 65 Query: 62 STNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLE 121 T++ S+L + AIK+ +V + G P K +++ + DV EK +L + Sbjct: 66 FTDEPSRLGEMALKAIKMTGSLRGDVQVGSGAPSVDKTMVRSSRPPSDVPAAEKRELVSD 125 Query: 122 VEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWK 181 D + ++ SY D + +LNSEGS+IE R+ L+AVA +Q K Sbjct: 126 AHHAASVDGVVSTTVSYVDMESSSAFLNSEGSLIEMAETRVALFLNAVASDGSGIQFGHK 185 Query: 182 SFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGH 241 S GGT G+E++E D KA+ LL A PPSG I+ DPEL GVFIHEALGH Sbjct: 186 SCGGTGGFEILEREDIEELGRRTGEKAVRLLKASPPPSGRFDIVTDPELTGVFIHEALGH 245 Query: 242 AVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDG 301 A EAD + QG+SIL G +G+KI SE +T+IDDPT+ G FGSY YD EG+ ++++G Sbjct: 246 AAEADLILQGDSILEGKLGEKIASEGVTIIDDPTIDG-FGSYSYDAEGVRAAETVLVENG 304 Query: 302 VLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVY 361 VL + LN RET+ L L P+G+ R+ + P+VRMSNTY+ PG+ + +E+ E+++ GVY Sbjct: 305 VLTSLLNSRETAFKLGLEPSGNARS-AIGDQPIVRMSNTYLKPGDLSFDELIEDIRNGVY 363 Query: 362 MIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKI 421 + G +GGQVD G F F A E + I++GEI E V+DV +SGN+L+TLK + VG D ++ Sbjct: 364 LRGSRGGQVDTGKGIFQFNAAESFRIQDGEIAEPVKDVSLSGNVLETLKNVDGVGSDFRL 423 Query: 422 EFPGFCGK-GQWVPVDDGGPHVLVK-AIVGG 450 GFCGK GQ VPV DGGPHV ++ A+VGG Sbjct: 424 GI-GFCGKSGQSVPVGDGGPHVRIRNAMVGG 453 >sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|AAB99001.1| (U67542) conserved hypothetical protein [Methanococcus jannaschii] Length = 451 Score = 321 bits (814), Expect = 1e-86 Identities = 189/451 (41%), Positives = 277/451 (60%), Gaps = 18/451 (3%) Query: 9 IEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLI-NGWGFASTNDLS 67 IEK + DIR T+++GK+E + S G+ VRVL NGWGF ++N +S Sbjct: 7 IEKLLEVGDYADIRINFGESNTITLKDGKIEEISSGFGNGVAVRVLYKNGWGFVTSNIVS 66 Query: 68 K--LEDTIKMAIKLAKVSN--AEVPLYVGNPVEGKAIIKQKKDF-----LDVDLEEKTKL 118 + +E I A K+AK+SN +E + + + KAII K DVD+EEK ++ Sbjct: 67 EEEIEKLINKAYKMAKISNEYSEKEIILK---DYKAIIDNYKMIGKINPTDVDIEEKKEI 123 Query: 119 GLEVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT 178 ++ K + +KIK+ SYSD ++I++ SEGS IE + R ++ VA+ +Q Sbjct: 124 IIDTYKNMTDEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNCVAKENGNLQ- 182 Query: 179 YWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEA 238 Y G G+E ++ N A ++AL LL A+ P G+ +I+DPELAGVFIHEA Sbjct: 183 YGAERTGGFGFEKIKDNYLNL-ALEAKNRALRLLKAKPCPKGKFKVILDPELAGVFIHEA 241 Query: 239 LGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298 +GHA EAD V Q +S+ +G+++GSE +TVIDD T+ G FGSY YDDEG+ GK+ II Sbjct: 242 VGHASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYKYDDEGVEGKKTVII 301 Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358 ++G+L YL+ RET+ ++ G+GRA+ + P+VRMSNT+I PG+W+ EE+ E+ K Sbjct: 302 ENGILKTYLHSRETAGRMDAELTGNGRAEG-LNKPIVRMSNTFIKPGDWSFEELLEDTKE 360 Query: 359 GVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418 G+++ G +GGQVD G F F A E Y+I+ GE+ + ++D G+SG ILD L ++ AV +D Sbjct: 361 GIFLKGSRGGQVDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGEILDILFKVDAVTKD 420 Query: 419 LKIEFPGFCGK-GQWVPVDDGGPHVLVKAIV 448 ++ G+CGK GQ VPV DGG V A V Sbjct: 421 FELSV-GYCGKDGQSVPVGDGGGCVRTIATV 450 >pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii Length = 451 Score = 321 bits (813), Expect = 1e-86 Identities = 189/449 (42%), Positives = 274/449 (60%), Gaps = 14/449 (3%) Query: 9 IEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLI-NGWGFASTNDLS 67 IEK + DIR T+++GK+E + S G+ VRVL NGWGF ++N +S Sbjct: 7 IEKLLEVGDYADIRINFGESNTITLKDGKIEEISSGFGNGVAVRVLYKNGWGFVTSNIVS 66 Query: 68 K--LEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDF-----LDVDLEEKTKLGL 120 + +E I A K+AK+SN E + KAII K DVD+EEK ++ + Sbjct: 67 EEEIEKLINKAYKMAKISN-EYSEKEXILKDYKAIIDNYKMIGKINPTDVDIEEKKEIII 125 Query: 121 EVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW 180 + K + +KIK+ SYSD ++I++ SEGS IE + R ++ VA+ +Q Y Sbjct: 126 DTYKNMTDEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNCVAKENGNLQ-YG 184 Query: 181 KSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG 240 G G+E ++ N A ++AL LL A+ P G+ +I+DPELAGVFIHEA+G Sbjct: 185 AERTGGFGFEKIKDNYLNL-ALEAKNRALRLLKAKPCPKGKFKVILDPELAGVFIHEAVG 243 Query: 241 HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD 300 HA EAD V Q +S+ +G+++GSE +TVIDD T+ G FGSY YDDEG+ GK+ II++ Sbjct: 244 HASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYKYDDEGVEGKKTVIIEN 303 Query: 301 GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV 360 G+L YL+ RET+ ++ G+GRA+ + P+VRMSNT+I PG+W+ EE+ E+ K G+ Sbjct: 304 GILKTYLHSRETAGRMDAELTGNGRAEG-LNKPIVRMSNTFIKPGDWSFEELLEDTKEGI 362 Query: 361 YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420 ++ G +GGQVD G F F A E Y+I+ GE+ + ++D G+SG ILD L ++ AV +D + Sbjct: 363 FLKGSRGGQVDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGEILDILFKVDAVTKDFE 422 Query: 421 IEFPGFCGK-GQWVPVDDGGPHVLVKAIV 448 + G+CGK GQ VPV DGG V A V Sbjct: 423 LSV-GYCGKDGQSVPVGDGGGCVRTIATV 450 >pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (strain Orsay) >gi|5458032|emb|CAB49522.1| (AJ248284) TLDD RELATED PROTEIN [Pyrococcus abyssi] Length = 458 Score = 290 bits (735), Expect = 2e-77 Identities = 167/436 (38%), Positives = 253/436 (57%), Gaps = 13/436 (2%) Query: 15 EVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTI 73 + +++++R+E+ T T+++G G+ +RVL NG WGF+ST+DLSKLE+ I Sbjct: 19 KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAI 78 Query: 74 KMAIKLAKVSNA----EVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRD 129 K A KLAK ++ ++ L PVE K K +VD+EEK K E+EK+++ D Sbjct: 79 KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKED 138 Query: 130 K-IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGT-V 187 + +K+ Y D +KI L +EG+ IE ++ S+ + + S G Sbjct: 139 ETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDY 198 Query: 188 GWELVESVDFNYWA-NFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246 GWEL+ + N + + K S L+ +P GE P++ P + G+ HEALGH EAD Sbjct: 199 GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEAD 258 Query: 247 SVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNY 306 S ++GK+I E +T+ + + G FG+ YDDEG+P K + II++G+L Sbjct: 259 LTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEI 315 Query: 307 LNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDK 366 + +RE + N+ PNGH RAQ Y + P++RM NT PG+W+ EEM E++KFG Y++ + Sbjct: 316 MLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFR 375 Query: 367 GGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGF 426 GGQ + N +F G +EGY+I+ GEI E +RD I+G ++ LK+I AVG+D IE GF Sbjct: 376 GGQAQL-NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIE-TGF 433 Query: 427 CGKGQWVPVDDGGPHV 442 CGKGQ V GGPH+ Sbjct: 434 CGKGQIAFVSSGGPHM 449 >gi|11498263 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|3123065|sp|O29602|Y655_ARCFU HYPOTHETICAL PROTEIN AF0655 >gi|7429834|pir||G69331 conserved hypothetical protein AF0655 - Archaeoglobus fulgidus >gi|2649963|gb|AAB90585.1| (AE001059) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 425 Score = 290 bits (735), Expect = 2e-77 Identities = 180/441 (40%), Positives = 264/441 (59%), Gaps = 23/441 (5%) Query: 16 VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTN--DLSKLEDT 72 ++F DIR + +ENGK+E N+ G RVL NG WG N D L Sbjct: 1 MRFWDIRRVENVSLNLQLENGKLEKPRYNKSTSKGFRVLKNGFWGIFEGNVADDEGLRQA 60 Query: 73 IKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIK 132 K A E+ +G+ ++ K+D D+ +EEK +L ++EK+IR D Sbjct: 61 EKNAFTQGDGDIEEIA------TKGRYRMRVKRDPQDMSIEEKVELLKDLEKIIR-DVCV 113 Query: 133 TSRFSYSDFVTRKI--YLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWE 190 +++ Y F R++ Y +S GS +E V R S+ V + + Q K G+E Sbjct: 114 STKLVY--FENRRVLQYRDSCGSEVEYEVLRTGVSIMGVGKGRSL-QFLSKRQMRVGGYE 170 Query: 191 LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQ 250 +++ VD + I L++A +PPSGEM ++MD LAGVF+HEA GHAVEAD V Q Sbjct: 171 VLDGVDEKAYE--IVEVLPKLVNALAPPSGEMSVVMDSSLAGVFVHEAFGHAVEADHVLQ 228 Query: 251 GESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDR 310 G ++L G + +K+ E +T+IDDPTLP +FG + +DDEG+ ++ I++DGVL ++L+ R Sbjct: 229 GATVLKGRLNEKVADESVTIIDDPTLP-EFGFFPFDDEGVRAEKKVIVEDGVLKSFLHSR 287 Query: 311 ETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV 370 ET+K L V G+ R+Q VP+VRMSNTYI ++ +E+ EE + GVY++G +GG+ Sbjct: 288 ETAKKLGGVA-GNARSQG-VDVPIVRMSNTYIDTHHYSFDELLEECRDGVYLVGSRGGET 345 Query: 371 DIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFCGK- 429 + A G F F A+ GY+IK GE+ E VRDV +SGN L+ L+ +K +GR+++ + PGFCGK Sbjct: 346 NPATGYFHFNAQYGYLIKNGELAEMVRDVSLSGNTLEILRNVK-IGREIEFD-PGFCGKA 403 Query: 430 GQWVPVDDGGPHVLVKAIVGG 450 GQ VPV DG P VL +A VGG Sbjct: 404 GQLVPVSDGSPPVLCRATVGG 424 >pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii >gi|3257986|dbj|BAA30669.1| (AP000006) 458aa long hypothetical protein [Pyrococcus horikoshii] Length = 458 Score = 281 bits (711), Expect = 1e-74 Identities = 161/436 (36%), Positives = 249/436 (56%), Gaps = 13/436 (2%) Query: 15 EVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTI 73 + +++++R+E+ T +++G G+ +RVL+NG WGF+ST++L K+E+ I Sbjct: 19 KAEYIELRYEDIKRTALNLKDGVFVNFTEKLNRGVAIRVLVNGAWGFSSTSELDKVEEAI 78 Query: 74 KMAIKLAKVSNA----EVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRD 129 K A KLAKV++ ++ L PVE K K +VD+EEK E+E +++ D Sbjct: 79 KEAYKLAKVASETKKEKIKLAEIKPVEDFVKSKMKIKPREVDIEEKINHLKELENLLKED 138 Query: 130 K-IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGT-V 187 K +K+ Y D +KI L +EG+ IE ++ + + + + G Sbjct: 139 KAVKSVNIRYEDGGGQKILLTNEGTKIEWDYNYLWQGVYVTGKEDGKLAMARDTIGAVDY 198 Query: 188 GWELVESVDFNYWA-NFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246 GWEL+ + N + I K S L +P GE P++ P + G+ HEALGH EAD Sbjct: 199 GWELMTEKEPNEKVRDRILRKLHSQLKGITPKRGEFPVVAGPIIVGIIAHEALGHLAEAD 258 Query: 247 SVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNY 306 S ++GK+I E +T+ + + G FG+ YDDEG+P + + II++G+L Sbjct: 259 LTMN--SPFKDLLGKQIAPEYVTM-SERHVEGGFGNDKYDDEGVPVRDIHIIENGILKEI 315 Query: 307 LNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDK 366 + +RE + N+ PNGH RAQ Y + P++RM NT PG+W+ EEM E++KFG Y++ + Sbjct: 316 MLNREYATKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFR 375 Query: 367 GGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGF 426 GGQ + N +F G +EGY+I+ GEI E +RD I+G ++ LK+I AVG+D IE GF Sbjct: 376 GGQAQL-NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKITAVGKDFGIEV-GF 433 Query: 427 CGKGQWVPVDDGGPHV 442 CGKGQ V GGPH+ Sbjct: 434 CGKGQTAFVSSGGPHM 449 >pir||G75033 hypothetical protein PAB1547 - Pyrococcus abyssi (strain Orsay) >gi|5458677|emb|CAB50164.1| (AJ248287) hypothetical protein [Pyrococcus abyssi] Length = 473 Score = 260 bits (657), Expect = 3e-68 Identities = 154/451 (34%), Positives = 258/451 (57%), Gaps = 22/451 (4%) Query: 18 FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSK--LEDTIK 74 + + RFE T +++NG +G++ + GIG+RVL++G GFASTN L+K + +T++ Sbjct: 19 YAEARFEEKQGTSLSMKNGVPQGMQLLSDRGIGIRVLVDGGMGFASTNILTKESIVETVQ 78 Query: 75 MAIKLAKVSNA--EVPLYVGNPVEGKAI--IKQKKDFLDVDLEEKTKLGLEVEKMIRRDK 130 A+KLAK ++ + P+ + +K KKDF DV EEK +L ++E+ + Sbjct: 79 RAVKLAKSASKLRKEPIKFSDEYFHNVYYEVKMKKDFRDVPPEEKLELLKKIEEEVLSTN 138 Query: 131 IKTSR--FSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVA-RSADIMQTYWKSFGGTV 187 +K +YSD V KI++NSE +V+E+V+PR+ + V + Q + S + Sbjct: 139 VKVPMRYLAYSDHVWHKIFVNSENAVVESVIPRVSVMYNLVVYEEGQMEQAPFVSRAFSG 198 Query: 188 GWELVESVD-FNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246 G EL+E + + + + + + PP G++ +++ PE+AG+ +HE++GH E D Sbjct: 199 GLELIEKDEPWERAKKEVETLKRIITEGKKPPEGKVDLVISPEVAGIAVHESVGHPYELD 258 Query: 247 SVRQGESILSG-------MIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIK 299 + E+ +G M+G++IGSE +TVIDDPT+P +G Y+YDDEG+ + +I+ Sbjct: 259 RIMGREAAQAGESFVKPDMLGERIGSEVVTVIDDPTIPNSWGFYLYDDEGVKARPRYLIR 318 Query: 300 DGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFG 359 +G++ +L +RE + L L N RA +Y P+VRM+NTY+APG+++ EE+ E++K G Sbjct: 319 NGIITEFLMNREYAAKLGLRSNAAARAINYNREPIVRMANTYLAPGDYSFEELIEDIKLG 378 Query: 360 VYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDL 419 VYM+ +D + +E Y+I+ GEIK V+ + + AVG+++ Sbjct: 379 VYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKHPVKRPILEITTRGLWSSVDAVGKEV 438 Query: 420 KIEFPGFCGK---GQWVPVDDGGPHVLVKAI 447 + PG CGK GQ VPV GG H ++ I Sbjct: 439 EFH-PGTCGKGEPGQGVPVWMGGAHARLRDI 468 >pir||D71135 tldD-related protein PH0848 - Pyrococcus horikoshii >gi|3257259|dbj|BAA29942.1| (AP000003) 481aa long hypothetical protein [Pyrococcus horikoshii] Length = 481 Score = 254 bits (642), Expect = 2e-66 Identities = 156/453 (34%), Positives = 253/453 (55%), Gaps = 26/453 (5%) Query: 18 FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSK--LEDTIK 74 + + RFE ++NG EG+E + GIGVRVL+NG GFASTN L+K + +T+K Sbjct: 27 YAEARFEEKQGISLAMKNGIPEGMEILSDKGIGVRVLVNGGMGFASTNVLTKESIAETVK 86 Query: 75 MAIKLAKVSNA--EVPLYVGNPVEGKAI--IKQKKDFLDVDLEEKTKLGLEVEKMIRRDK 130 A+KLAK ++ + P+ +K KKDF DV EEK +L ++E+ + Sbjct: 87 RAVKLAKAASKLRKEPITFSEEDFHNVYYEVKMKKDFRDVSPEEKLELLKKIEEEVTSTN 146 Query: 131 IKTSR--FSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT---YWKSFGG 185 + +YSD V K+++NSE + IE+++PR+ + V M+ ++F G Sbjct: 147 VNVPMRYIAYSDHVWHKVFMNSENAKIESLIPRVSVMYNLVVFENGQMEQAPFIQRAFSG 206 Query: 186 TVGWELVESVD-FNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVE 244 G EL+E + + + + + + P G++ +I+ PE+AG+ +HE++GH E Sbjct: 207 --GLELIEKDEPWERAKREVETLRKIITEGKRSPEGKVDVIISPEVAGIAVHESVGHPYE 264 Query: 245 ADSVRQGESILSG-------MIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEI 297 D + E+ +G M+G++IGSE +TVIDDPT+P +G Y+YDDEG+ + + Sbjct: 265 LDRIMGREAAQAGESFVKPEMLGERIGSEVVTVIDDPTIPNSWGFYLYDDEGVKARPRYL 324 Query: 298 IKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVK 357 I++G++ +L +RE + L L N RA +Y P+VRM+NTY+APG+++ EE+ E+VK Sbjct: 325 IRNGIITEFLMNREYAAKLGLRSNAAARAINYNREPIVRMANTYLAPGDYSFEELIEDVK 384 Query: 358 FGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGR 417 GVYM+ +D + +E Y+I+ GEIK V+ + + AVG+ Sbjct: 385 LGVYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKHPVKRPILEITTRGLWSSVDAVGK 444 Query: 418 DLKIEFPGFCGK---GQWVPVDDGGPHVLVKAI 447 +++ + G CGK GQ VPV GG H ++ I Sbjct: 445 EVEF-YAGTCGKGEPGQGVPVWMGGAHARLRDI 476 >pir||D72762 hypothetical protein APE0089 - Aeropyrum pernix (strain K1) >gi|5103477|dbj|BAA78998.1| (AP000058) 489aa long hypothetical protein [Aeropyrum pernix] Length = 489 Score = 252 bits (637), Expect = 6e-66 Identities = 159/462 (34%), Positives = 248/462 (53%), Gaps = 20/462 (4%) Query: 5 LRNLIEKYSNE-VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFAS 62 L L+EK ++ + + RF + V N +V G E G+ RV+++G GFAS Sbjct: 26 LEKLVEKALDKGASYAEARFHARLGDSVLVVNDRVVGGGFEIEEGVAFRVIVDGALGFAS 85 Query: 63 TNDLSK--LEDTIKMAIKLAKVSNAEVPLYVGNPVE--GKA--IIKQKKDFLDVDLEEKT 116 T+ LS+ L+ + A+ +A+ S+ VG E G+A +K KKDF +++LE+K Sbjct: 86 TSLLSEESLDSVVDHAVSIARSSSRGFRKKVGMSEERLGQAQYSLKVKKDFRNLELEDKA 145 Query: 117 KLGLEVEKMIRRDKI--KTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSAD 174 + LE K + + K FSYSD + K+ + S+G IE+++PR+ + A D Sbjct: 146 SIVLEYSKSLESKSVDLKAKTFSYSDVLEAKLIITSDGGNIESIIPRVSIFYNIAAEHGD 205 Query: 175 IMQTYWKSFGGTVGWELVESVDF-NYWANFISSKALSLLSARSPPSGEMPIIMDPELAGV 233 W G+ G ELV + + + ++S ++L+ A P G M +I+ PE+ G+ Sbjct: 206 RRANKWGHLAGSGGLELVGELGLESMLKDDVNSLEVNLVKAEPSPKGVMDVIISPEIVGL 265 Query: 234 FIHEALGHAVEADSVRQGESILSGM-----IGKKIGSEELTVIDDPTLPGKFGSYVYDDE 288 +HE++GH EAD V E+ +G+ + +IGS ++TV DDPT+PG +G Y+YDDE Sbjct: 266 ALHESIGHPSEADRVMGREAAQAGLSYRMWLDGRIGSSKVTVADDPTVPGSYGFYLYDDE 325 Query: 289 GLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWT 348 +P + +I G L L+ R T+ + + NG RA +Y P+VRMSNTY+ PG+ Sbjct: 326 AVPARERILINKGELAELLHSRTTAYSFGVQSNGAARAMNYRSEPIVRMSNTYLKPGDMR 385 Query: 349 LEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDT 408 EE+ E+VK G+YM +D + E Y+IK G I + VRD + Sbjct: 386 FEELLEDVKEGIYMKSYMEWNIDEFRLVARYVGLEAYLIKNGRIVKPVRDTVLEIPTESF 445 Query: 409 LKEIKAVGRDLKIEFPGFCGKG---QWVPVDDGGPHVLVKAI 447 +I VG+DL+ + G CGKG Q +PV GGPHV V+ + Sbjct: 446 YSKIDGVGKDLRF-YAGICGKGEPPQPLPVWMGGPHVRVRDV 486 >gb|AAK40965.1| Zn-dependent protease, tldD protein homolog, putative (tldD) [Sulfolobus solfataricus] Length = 443 Score = 238 bits (600), Expect = 1e-61 Identities = 154/439 (35%), Positives = 238/439 (54%), Gaps = 18/439 (4%) Query: 18 FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN-GWGFASTNDLSK--LEDTIK 74 F DIR+E I E T+ + + V + G +RV+ N WGF +T+ +++ +EDTI Sbjct: 15 FADIRYERVIANEVTITEDR-KYVSHGVDEGYSIRVIYNRNWGFKATDKITENEIEDTIN 73 Query: 75 MAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTS 134 +V+ +P GK I K +++ ++ DL K+ +V + IK+ Sbjct: 74 HIYGDERVNIVYLPSKHDTIKIGKDINKNEEEKIN-DLH---KVASQVNTL--HPSIKSY 127 Query: 135 RFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVES 194 Y D + K Y +SE I S+ VAR D+ + +G+ + + Sbjct: 128 SIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAREGDVTVEVSEILSTQMGY-IFDV 186 Query: 195 VDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESI 254 D N + + ++ L +P +GE P+I+ PE+ G+F HEA+GH EAD G Sbjct: 187 FDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVGIFTHEAIGHLSEADVTLNGS-- 244 Query: 255 LSGMIGKKIGSEELTVIDDPTLPGKFGSYVY-DDEGLPGKRVEIIKDGVLLNYLNDRETS 313 L + K+IG E L + D P + S VY DDEG+ G+ V+II++G+L ++ DR S Sbjct: 245 LYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGREVKIIENGILKEFMTDRYYS 304 Query: 314 KALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIA 373 L P G+ RAQSY + L+RM NTY+ PG+ +L E+FE +K G Y++ GG+ + Sbjct: 305 AYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELFEGIKEGYYLVSPIGGETS-S 363 Query: 374 NGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFCGK-GQW 432 NG+F F +EGY ++ EIKE +R++GISGN + TL I+ + +D + GFC K GQ Sbjct: 364 NGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEMISKDFGMS-SGFCEKNGQT 422 Query: 433 VPVDDGGPHVLVKAI-VGG 450 V V +GGPH+ VK + VGG Sbjct: 423 VQVSNGGPHIKVKKLKVGG 441 >emb|CAB57642.1| (Y18930) hypothetical protein [Sulfolobus solfataricus] Length = 443 Score = 238 bits (600), Expect = 1e-61 Identities = 154/439 (35%), Positives = 238/439 (54%), Gaps = 18/439 (4%) Query: 18 FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN-GWGFASTNDLSK--LEDTIK 74 F DIR+E I E T+ + + V + G +RV+ N WGF +T+ +++ +EDTI Sbjct: 15 FADIRYERVIANEVTITEDR-KYVSHGVDEGYSIRVIYNRNWGFKATDKITENEIEDTIN 73 Query: 75 MAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTS 134 +V+ +P GK I K +++ ++ DL K+ +V + IK+ Sbjct: 74 HIYGDERVNIVYLPSKHDTIKIGKDINKNEEEKIN-DLH---KVASQVNTL--HPSIKSY 127 Query: 135 RFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVES 194 Y D + K Y +SE I S+ VAR D+ + +G+ + + Sbjct: 128 SIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAREGDVTVEVSEILSTQMGY-IFDV 186 Query: 195 VDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESI 254 D N + + ++ L +P +GE P+I+ PE+ G+F HEA+GH EAD G Sbjct: 187 FDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVGIFTHEAIGHLSEADVTLNGS-- 244 Query: 255 LSGMIGKKIGSEELTVIDDPTLPGKFGSYVY-DDEGLPGKRVEIIKDGVLLNYLNDRETS 313 L + K+IG E L + D P + S VY DDEG+ G+ V+II++G+L ++ DR S Sbjct: 245 LYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGREVKIIENGILKEFMTDRYYS 304 Query: 314 KALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIA 373 L P G+ RAQSY + L+RM NTY+ PG+ +L E+FE +K G Y++ GG+ + Sbjct: 305 AYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELFEGIKEGYYLVSPIGGETS-S 363 Query: 374 NGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFCGK-GQW 432 NG+F F +EGY ++ EIKE +R++GISGN + TL I+ + +D + GFC K GQ Sbjct: 364 NGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEMISKDFGMS-SGFCEKNGQT 422 Query: 433 VPVDDGGPHVLVKAI-VGG 450 V V +GGPH+ VK + VGG Sbjct: 423 VQVSNGGPHIKVKKLKVGG 441 >sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD protein - Escherichia coli (strain K-12) >gi|606183|gb|AAA58046.1| (U18997) ORF_f481 [Escherichia coli] >gi|1732437|dbj|BAA07913.1| (D44451) TldD protein [Escherichia coli] >gi|1789640|gb|AAC76276.1| (AE000403) suppresses inhibitory activity of CsrA [Escherichia coli K12] Length = 481 Score = 231 bits (584), Expect = 1e-59 Identities = 141/444 (31%), Positives = 239/444 (53%), Gaps = 14/444 (3%) Query: 20 DIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKLEDTIKMA 76 D+ F+++ + + +E+ ++ N + G+GVR + G+ +A L LE + + A Sbjct: 37 DLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAA 96 Query: 77 IKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRR--DKIKTS 134 + + S +G VE + + EEK + V+K+ R +++ Sbjct: 97 RTIVRDSGDGKVQTLG-AVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEV 155 Query: 135 RFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWE---- 190 S S + ++G++ V P + S+S + + GG G+E Sbjct: 156 TASLSGVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLA 215 Query: 191 -LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVR 249 L V + WA AL LSA + P+G MP+++ GV +HEA+GH +E D R Sbjct: 216 DLDGEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNR 275 Query: 250 QGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLND 309 +G S+ SG +G+ + SE TV+DD T+ + GS DDEG PG+ +I++G+L Y+ D Sbjct: 276 RGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQD 335 Query: 310 RETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQ 369 + ++ + + P G+GR +SYAH+P+ RM+NTY+ PG+ T +E+ E V++G+Y GGQ Sbjct: 336 KLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQ 395 Query: 370 VDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIE-FPGFCG 428 VDI +G F+F E Y+I+ G++ + V+ + G+ ++T+++I VG DLK++ G CG Sbjct: 396 VDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCG 455 Query: 429 K-GQWVPVDDGGPHVLVKAI-VGG 450 K GQ +PV G P + V + VGG Sbjct: 456 KEGQSLPVGVGQPTLKVDNLTVGG 479 >pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9654844|gb|AAF93595.1| (AE004129) tldD protein [Vibrio cholerae] Length = 481 Score = 223 bits (563), Expect = 3e-57 Identities = 142/465 (30%), Positives = 248/465 (52%), Gaps = 38/465 (8%) Query: 13 SNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKL 69 + ++ + DI F+++ + +E+ ++ N + G+GVR + G+ ++ L L Sbjct: 30 TRQIDYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAYSDQIQLEGL 89 Query: 70 EDTIKMAIKLAK---------VSNAEVPLYVG--NPVEGKAIIKQKKDFLDVDLEEKTKL 118 + + A +A+ A+ P + G NP+E + ++KT+L Sbjct: 90 KQSAIAARGIAQQGQNLTVQAFKRAQHPAFYGAHNPLESW------------EKQQKTEL 137 Query: 119 GLEVEKMIRRDK--IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIM 176 +++ IR + I S S + + ++G+ + P + S+S +A+ D Sbjct: 138 LKQLDAYIRTKEPLITEVSVSLSGVHEQILVAATDGTYAGDIRPLVRLSISVLAQKGDRR 197 Query: 177 QTYWKSFGGTVGW------ELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPEL 230 + GG G+ E + + F++ A+ +AL L A + P+G MP+++ Sbjct: 198 ERGSAGGGGRFGYDYFLQEEAGQKIAFSF-ADEAIRQALVNLEAVAAPAGTMPVVLGSGW 256 Query: 231 AGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGL 290 GV +HEA+GH +E D R+G S+ +G +GKK+ S+ T++DD TL GS DDEG+ Sbjct: 257 PGVLLHEAVGHGLEGDFNRKGSSVFAGKVGKKVTSDLCTIVDDGTLKDLRGSLNVDDEGV 316 Query: 291 PGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLE 350 G+ +I+ G+L Y+ D+ ++ + + P G+GR +SYAH+P+ RM+NTY+ PGE T E Sbjct: 317 SGQYNVLIEKGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPE 376 Query: 351 EMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLK 410 E+ VK G+Y GGQVDI +G F+F A E Y+I+ G+I ++ + G+ ++ ++ Sbjct: 377 EIIASVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIENGKITRPIKGATLIGSGIEAMQ 436 Query: 411 EIKAVGRDLKIE-FPGFCGK-GQWVPVDDGGPHVLVKAI-VGGRE 452 ++ VG DL ++ G CGK GQ VPV G P + + A+ VGG E Sbjct: 437 QVSMVGNDLALDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGTE 481 >sp|P73754|Y863_SYNY3 HYPOTHETICAL 50.4 KD PROTEIN SLR0863 >gi|7429837|pir||S74845 tldD homolog slr0863 - Synechocystis sp. (strain PCC 6803) >gi|1652888|dbj|BAA17806.1| (D90909) hypothetical protein [Synechocystis sp.] Length = 463 Score = 220 bits (556), Expect = 2e-56 Identities = 146/455 (32%), Positives = 238/455 (52%), Gaps = 14/455 (3%) Query: 5 LRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFAST 63 L LI +Y ++ F+ IR E + T+ ++ + +VE + +G VRV G WGFAS Sbjct: 10 LPELIGRYQSQADFISIRLEQSEGTQISLRSDQVETLSEGIAMGGQVRVCHQGGWGFASF 69 Query: 64 NDLSKLEDTIKMAIKLAK-VSNAEVPLYVGNPVEGKAIIKQK-KDFLDVDLEEKTKLGLE 121 N +L ++ AI A+ + + E L +PV+ I KD + L +K L Sbjct: 70 NRWEQLRQRLEEAIAAARLIGDDETLLAPIDPVQQTFINPLTGKDPRQISLADKKALCDH 129 Query: 122 VEKMIR--RDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTY 179 ++R DKI T+ YSD + SEG+++E + +A A+ + +Q Sbjct: 130 YNDLLRGTSDKITTTHVRYSDSQQTVLLATSEGTLLEQCWWDLEMRFAATAKDGNGVQVG 189 Query: 180 WKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEAL 239 ++ G G+ +E++D + +A+ L+ + P+++DP L G+F+HEA Sbjct: 190 RETTGSRRGYGDLENLD--QVVQGAAQRAVKALTLPTVQGKTYPVVIDPILTGLFVHEAF 247 Query: 240 GHAVEADSVRQGESILSGM-IGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298 GH EAD + + L M +G++ G EL + D PG GSY +DDEG+P ++I Sbjct: 248 GHLSEADMLYENPDFLEVMSLGRRFGPPELQIFDGAAPPGHRGSYGFDDEGVPASTTQLI 307 Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358 KDG L+ L+ RET+ L P G+ R +Y + P+VRM+NT+I GE + + + ++ Sbjct: 308 KDGELVGRLHSRETAGKLGEKPTGNARCLNYHYPPIVRMTNTWIGRGETPVANLLDGIEE 367 Query: 359 GVYMIGDKGGQVDIANGS-FMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGR 417 G+Y GG + NG F F A E ++I+ G++ E V+DV +SGN+ TL I+A+ Sbjct: 368 GIYAQNWLGG---MTNGEMFTFSAGEAWMIRHGQLAEPVKDVTLSGNVFKTLANIEAIAD 424 Query: 418 DLKIEFPGFCGKG--QWVPVDDGGPHVLVKAIVGG 450 D + G CGKG + V GGP + ++ +V G Sbjct: 425 DFYWDESGGCGKGGQNGLAVGCGGPSLRIRDVVVG 459 >gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum] Length = 479 Score = 219 bits (552), Expect = 5e-56 Identities = 139/425 (32%), Positives = 230/425 (53%), Gaps = 9/425 (2%) Query: 34 ENGKVEGVESNEEVGIGVR-VLINGWGFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVG 92 +NG+++ + G G+R V + G+A ++D+S L I+ A +A V + Sbjct: 53 DNGRLKQATYDTSQGFGLRAVKDDAVGYAHSSDVS-LPALIRAADAVAAVRGGYSGSFSA 111 Query: 93 NPVEGKAIIKQKKDFLDVD-LEEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTRKIY--LN 149 P + + LD E K KL E++ +R + + S + T ++ L Sbjct: 112 PPPHTNVRLYGDDNPLDAPGFETKVKLLAEIDAYLRDKDPRVRQVSVTLGATWQVVEILR 171 Query: 150 SEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGW-ELVESVDFNYWANFISSKA 208 +G + P + ++S VA D ++ K +GG G+ E +ES ++ A+ +A Sbjct: 172 PDGESYRDIRPLVRVNISVVAGQGDRQESGSKGYGGRAGYAEFIESKNWRDAADGALREA 231 Query: 209 LSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEEL 268 L L + P+GEM +++ GV +HEA+GH +E D R+ S +G++G+++ ++ + Sbjct: 232 LVNLESIPAPAGEMDVVLGAGWPGVMLHEAVGHGLEGDFNRKRTSAFAGLMGRQVAAKGV 291 Query: 269 TVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQS 328 TV+DD T+ + GS DDEG P R +I+DG+L+ Y+ DR+ ++ +N+ P G+GR Q Sbjct: 292 TVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGILVGYMQDRQNARLMNMKPTGNGRRQG 351 Query: 329 YAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIK 388 YAHVP+ RM+NTY+ G+ E+ VK GV+ GGQVDI +G ++F E Y I+ Sbjct: 352 YAHVPMPRMTNTYMLAGDRDPAEILASVKNGVFAANFGGGQVDITSGKYVFQCTEAYKIE 411 Query: 389 EGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFP-GFCGK-GQWVPVDDGGPHVLVKA 446 G+I ++ + GN L I+ +G DL ++ G CGK GQ VPV G P +L++ Sbjct: 412 NGKIGAPLKGAMLIGNGPTDLHRIRMIGNDLALDTGIGTCGKNGQGVPVGVGQPSLLMER 471 Query: 447 I-VGG 450 I VGG Sbjct: 472 ITVGG 476 >pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07784.1| (AE000768) TldD protein [Aquifex aeolicus] Length = 404 Score = 217 bits (548), Expect = 2e-55 Identities = 126/387 (32%), Positives = 210/387 (53%), Gaps = 12/387 (3%) Query: 17 KFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING---WGFASTNDLSKLEDTI 73 ++ +I +E + T +E+ K++ V + G+G+R++ NG +G+ + L++ Sbjct: 19 EYGEIFYEKSRTTRMHLEDRKIDKVTHGYDEGVGLRLIKNGKTYYGYTTNPTFENLKELA 78 Query: 74 KMAIKLAKVSNAEVPLYVGNP-VEG--KAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDK 130 K+ + P+ +G ++G + +I K+ L E + + DK Sbjct: 79 KILAR----GEGHGPVAIGKRYIQGYTEVLIDPDKESLKFRAEILRRADEKARSF--GDK 132 Query: 131 IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWE 190 IK D + +N+ G E R+ F + VA + +Q ++S GG G+E Sbjct: 133 IKQVLAVLMDKTREIMVINTLGETAEDTQKRVVFFVEVVASDGETLQRGYESLGGRRGFE 192 Query: 191 LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQ 250 + A + +AL +LSA+ P+G ++M + G IHEA+GH +EAD V+Q Sbjct: 193 IFNETPPEVIAEKAAKRALLMLSAKPAPAGTFTVVMSSQAGGTMIHEAVGHGLEADLVQQ 252 Query: 251 GESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDR 310 G S+ +G +G+K+ SE +TVIDD TLP GS+ DDEG+P +R +IKDGVL+ Y+ DR Sbjct: 253 GLSVYAGKLGEKVASELVTVIDDATLPYHNGSFTVDDEGVPAQRKVLIKDGVLVGYMYDR 312 Query: 311 ETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV 370 + + G+GR QSYAH+P+VRM+NT+I G+ E++ ++ K GV ++ GG+V Sbjct: 313 LRAMKDGVESTGNGRRQSYAHIPIVRMTNTFIDKGQDNPEDIIKDTKKGVLVVKMGGGEV 372 Query: 371 DIANGSFMFGAKEGYIIKEGEIKEQVR 397 + G F+F EGY+I+ GEI +R Sbjct: 373 NTVTGDFVFEVMEGYMIENGEITYPIR 399 >pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9106089|gb|AAF83937.1|AE003949_1 (AE003949) TldD protein [Xylella fastidiosa] Length = 485 Score = 215 bits (542), Expect = 8e-55 Identities = 138/455 (30%), Positives = 246/455 (53%), Gaps = 24/455 (5%) Query: 16 VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTIK 74 V F D+ F++ +++E+G V+ + E G+GVR + GFA ++D+++ + ++ Sbjct: 36 VDFGDLYFQHARRESWSIEDGIVKDGTHSIEQGVGVRAISGEKTGFAYSDDINR-DALLE 94 Query: 75 MAIKLAKVSNAEVPLYVGNPVEGK--AIIKQKKDF-----LD----VDLEEKTKLGLEVE 123 A +S + G+ V+G ++ Q+++ LD +D EK + V+ Sbjct: 95 AAYAARAISRSP-----GDGVQGTHAVLLHQERELCLYPALDPVGGMDNAEKIAVMRRVD 149 Query: 124 KMIRR--DKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWK 181 +++R ++ + S V + S+G + V P + ++ + ++ + Sbjct: 150 QLLRAADPRVTQVMVNLSGGVDVVLIARSDGVLAADVRPLVRLNVQVIVEGHGRRESGYA 209 Query: 182 SFGGTVGW-ELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG 240 GG G+ EL +A +AL L A P+G MP+++ GV +HEA+G Sbjct: 210 GGGGRYGYAELFADGRPEAFAREALRQALVNLEAIPAPAGVMPVVLGAGWPGVLLHEAVG 269 Query: 241 HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD 300 H +E D R+G S+ +G IG+++ S +T++DD TL G+ GS DDEG P + +I+D Sbjct: 270 HGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPTQCTTLIED 329 Query: 301 GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV 360 GVL+ Y+ D ++ + + G+GR +S+AH+ + RM+NTY+ G + EEM VK G+ Sbjct: 330 GVLVGYMQDTLNARLMGVASTGNGRRESFAHLTMPRMTNTYMRAGVHSREEMIRSVKKGL 389 Query: 361 YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420 Y + GGQVDI +G ++F A E Y+I++G + ++ + GN +T++ ++ +G DL Sbjct: 390 YAVNFGGGQVDITSGKYVFSATEAYLIEDGRVTAPIKGATLIGNGPETMQRVRMIGDDLA 449 Query: 421 IEF-PGFCGK-GQWVPVDDGGPHVLVKAI-VGGRE 452 ++ G CGK GQ VPV G P +L+ + VGG + Sbjct: 450 LDAGVGVCGKDGQSVPVGVGQPSLLIDGLTVGGTQ 484 >sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13101.1| (AP001119) tldD protein [Buchnera sp. APS] Length = 483 Score = 215 bits (542), Expect = 8e-55 Identities = 140/469 (29%), Positives = 241/469 (50%), Gaps = 38/469 (8%) Query: 8 LIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVL---INGWGFASTN 64 L E + ++ + D+ F++ I+ + +EN ++ + + GIGVR + G+ ++ Sbjct: 25 LEELCTRQLDYGDLYFQSHIHESWILENSIIKEGNYHSDAGIGVRAIRGESTGFAYSDQI 84 Query: 65 DLSKLEDTIKMA--IKLAKVSNAEV--------PLYVG-NPVEGKAIIKQKKDFLDVDLE 113 L L + K A I L K S P+Y NP+EG + Sbjct: 85 SLDSLRRSTKKAHSIILTKGSGKTKTLSKKTIEPIYKNVNPLEG------------FSSK 132 Query: 114 EKTKLGLEVEKMIRR--DKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVAR 171 EKT L + R ++ S + + + +++G+++ + P I FS+S + Sbjct: 133 EKTDLLYRANYIARSLDHRVIEVNASLTGSYEQILVASTDGNLVSDIRPSIQFSISVLVE 192 Query: 172 SADIMQTYWKSFGGTVGWELVESVD-------FNYWANFISSKALSLLSARSPPSGEMPI 224 + G + + D ++W+ AL LS++ SG P+ Sbjct: 193 DHGKRERGRSGGGSRTDYNFFLNQDDSSKEIRIDHWSKEAVRIALLNLSSKEALSGTFPV 252 Query: 225 IMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYV 284 ++ GV +HEA+GH +E D R+G SI + MIGKK+ SE T+IDD T+ + GS Sbjct: 253 VLGSGWPGVLLHEAIGHGLEGDFNRKGTSIFTNMIGKKVASELCTIIDDGTIKNQRGSLS 312 Query: 285 YDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAP 344 DDEG PG++ +I++G+L Y+ D+ ++ + + G+GR +SY+ +P+ RM+NTY+ Sbjct: 313 IDDEGTPGQKNILIENGILKKYMQDKLNARLMGVKSTGNGRRESYSCLPMPRMTNTYMLS 372 Query: 345 GEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGN 404 G+ L+++ + V +G+Y + GGQVDI +G F+F E Y+IK G+I +++ + G+ Sbjct: 373 GKSKLDDIIKSVDYGIYAVNFSGGQVDITSGKFVFSTSEAYLIKNGKIVTPIKNTTLIGS 432 Query: 405 ILDTLKEIKAVGRDLKI-EFPGFCGK-GQWVPVDDGGPHV-LVKAIVGG 450 L+ +++I VG DLK+ E G CGK GQ +PV G P + L +GG Sbjct: 433 GLEVMQKISMVGDDLKMDEGMGICGKDGQNIPVGIGQPSMKLENLTIGG 481 >pir||D72342 tldD protein - Thermotoga maritima (strain MSB8) >gi|4981251|gb|AAD35808.1|AE001743_10 (AE001743) tldD protein [Thermotoga maritima] Length = 499 Score = 209 bits (527), Expect = 5e-53 Identities = 142/445 (31%), Positives = 227/445 (50%), Gaps = 16/445 (3%) Query: 18 FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWG-FASTNDLSKLEDTIKMA 76 F ++ FE + +++GK+E S E VG+G+R + +A TNDLS+ E+ I +A Sbjct: 58 FAELFFERKYENRYELKDGKIEQATSGEIVGVGIRGFLGTKAVYAYTNDLSR-ENLINVA 116 Query: 77 IKLAKV---SNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDK--- 130 K+ + + E + N + K ++ + EKT ++K K Sbjct: 117 KKVGEALGETKVEDLTFNFNRTKRK---ERHVVLIPPAQVEKTDKVSVMKKAYYAAKNYS 173 Query: 131 --IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVG 188 IK Y D+ + NSEG+ E R ++AVA +++ + G +G Sbjct: 174 ELIKQVVVWYWDYDQEILVANSEGTWAEDRRVRTRLMINAVAEKDGVLERGFYGPGAGMG 233 Query: 189 WELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSV 248 +E + +D A + A ++ A P+G+M +++ GV HEA+GH +EA SV Sbjct: 234 FEFFDRIDVEEAAKKAARIAARMVEAEPAPAGKMTVVIANGFGGVIFHEAVGHGLEATSV 293 Query: 249 RQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLN 308 +G S+ +G +G+K+ +E ++ +DD T+P +GS DDEG P +R +I GVL+ YL Sbjct: 294 AKGASVFAGKLGQKVAAECVSAVDDATIPNGWGSANVDDEGTPTQRTLLIDKGVLVGYLV 353 Query: 309 DRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGG 368 D+ + + + G GR Q Y P RMSNT+I PG++ EE+ ++G+Y GG Sbjct: 354 DKLGERRMGMKSTGSGRRQDYTFPPTSRMSNTFILPGDYHPEEIIAATEYGLYAKTMGGG 413 Query: 369 QVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFCG 428 V+ A G F F E Y+I++G I + VR + G + +++I VG DL + G CG Sbjct: 414 SVNPATGEFNFAVSEAYLIEKGRITKPVRGATLIGKGHEIIQKIDMVGNDLARD-QGMCG 472 Query: 429 K-GQWVPVDDGGPHVLVKAI-VGGR 451 VP D G P + VK I VGGR Sbjct: 473 SFSGSVPADVGQPTIRVKEIVVGGR 497 >pir||D83086 conserved hypothetical protein PA4474 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950711|gb|AAG07862.1|AE004861_3 (AE004861) conserved hypothetical protein [Pseudomonas aeruginosa] Length = 480 Score = 205 bits (516), Expect = 9e-52 Identities = 144/463 (31%), Positives = 238/463 (51%), Gaps = 19/463 (4%) Query: 2 IDELRNLIEKYSNE-VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WG 59 +D L ++ + + + D+ F++ + + +E+G V+ N + G+GVR G Sbjct: 20 LDSLPGILHELNGPGIDAADLYFQSQVSESWMLEDGIVKEGSFNLDQGVGVRAQSGEKTG 79 Query: 60 FASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQK----KDFLDV-DLEE 114 FA +N ++ E + A+ +S A G+ KA++ + ++ LDV E Sbjct: 80 FAYSNAITA-EALKQAAVAARSISRAGQN---GSVQAFKAVVPARLYAGENPLDVLSRAE 135 Query: 115 KTKLGLEVEKMIRR--DKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARS 172 K +L +++ R +I+ S + + + S+GS+ + P + F++S + Sbjct: 136 KVELLKQIDAATRALDPRIQQVTVSMAGVWEQILVAASDGSLAADIRPLVRFNVSVIVEQ 195 Query: 173 ADIMQTYWKSFGGTVGWE--LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPEL 230 + GG + L E Y A +AL L A P+G +P++M Sbjct: 196 NGRRERGGHGGGGRTDYRYFLQEDRAMGY-AREALRQALVNLEAIPAPAGTLPVVMGAGW 254 Query: 231 AGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGL 290 +GV +HEA+GH +E D R+G S SG +G+K+ S T++DD TL G+ GS DDEG Sbjct: 255 SGVLLHEAVGHGLEGDFNRKGSSAYSGRVGEKVASSLCTIVDDGTLAGRRGSLSVDDEGT 314 Query: 291 PGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLE 350 P +I++GVL Y+ D+ ++ + + G+GR +SYAH+P+ RM+NTY+ GE + Sbjct: 315 PSNCNVLIENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLAGESDPQ 374 Query: 351 EMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLK 410 E+ V+ G+Y GGQVDI +G F+F E Y+I+ G I V+ + GN + + Sbjct: 375 EIIASVEKGIYCANLGGGQVDITSGKFVFSTSEAYLIENGRITTPVKGATLIGNGPEAMS 434 Query: 411 EIKAVGRDLKIEF-PGFCGK-GQWVPVDDGGPHVLVKAI-VGG 450 + VG DL ++ G CGK GQ VPV G P + + AI VGG Sbjct: 435 RVSMVGNDLALDSGVGTCGKDGQSVPVGVGQPTLKIDAITVGG 477 >sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG Length = 482 Score = 199 bits (500), Expect = 7e-50 Identities = 133/464 (28%), Positives = 243/464 (51%), Gaps = 21/464 (4%) Query: 5 LRNLIEKYSNE-VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGF 60 L N+ + S+ + + D+ F+ + + +E+G ++ + + G+GVR + G+ + Sbjct: 20 LLNIFDIMSHRNIDYADLYFQLSQDESWVLEDGIIKEGSFHIDRGVGVRAVSGEKTGFAY 79 Query: 61 ASTNDLSKLEDTIKMAIKLAKVSNAEV----PLYVGNPVEGKAIIKQKKDFLDVDLEEKT 116 A +L+ L+ + +A+V + V NP+ A I + E+K Sbjct: 80 ADQINLASLQQCAEAVKGIAQVKQGNLISPSAFNVVNPIARYAAINPLESLTK---EKKI 136 Query: 117 KLGLEVEKMIRRDKIKTSRFS--YSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSAD 174 +L V++ R + + ++ S S + + ++G++ + P + S+S + Sbjct: 137 ELLHLVDRTARAEDHRVTKVSASLSSVYEEVLIMATDGTLAADIRPLVRLSISVLVEENG 196 Query: 175 IMQTYWKSFGGTVGWE-LVESVDFNYWANFISSKA----LSLLSARSPPSGEMPIIMDPE 229 + GG G + E VD + A + +A L LSA + P+G MP+++ Sbjct: 197 KRERGSCGSGGRFGLDWFFEVVDGDIRAVLFAKEAVRQALVNLSAVAAPAGLMPVVLGAG 256 Query: 230 LAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEG 289 GV +HEA+GH +E D R+ S+ +G IG+++ S T++DD T+ + GS DDEG Sbjct: 257 WPGVLLHEAVGHGLEGDFNRKESSLFTGKIGEQVTSPLCTIVDDGTIENRRGSLTIDDEG 316 Query: 290 LPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTL 349 +P + +IKDG+L Y+ D+ ++ + + G+GR +SYAH+P+ RM+NTY+ G+ Sbjct: 317 VPSQCNVLIKDGILQGYMQDKMNARLMGVSTTGNGRRESYAHLPMPRMTNTYMLAGQSQF 376 Query: 350 EEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTL 409 +++ VK G+Y GGQVDI +G F+F E Y+I++G+I + V+ + G+ ++ + Sbjct: 377 DDLIASVKQGIYAPHFGGGQVDITSGKFVFSTSEAYLIEKGKITKPVKGATLIGSGIEVM 436 Query: 410 KEIKAVGRDLKIEFP-GFCGK-GQWVPVDDGGPHVLVKAI-VGG 450 ++I V +++ G CGK GQ VPV G P + + I VGG Sbjct: 437 QKISMVADKSELDLGIGVCGKEGQSVPVGVGQPALKIDEITVGG 480 >pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379119|emb|CAB83668.1| (AL162752) TLDD protein homolog [Neisseria meningitidis Z2491] Length = 480 Score = 191 bits (481), Expect = 1e-47 Identities = 127/450 (28%), Positives = 225/450 (49%), Gaps = 16/450 (3%) Query: 13 SNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKL 69 ++ V + DI + T Y + +E G V+ G+GVR + + +A + + + Sbjct: 32 AHHVDYADIYCQRTAYESWHLEEGIVKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDSI 91 Query: 70 EDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRR- 128 + + A++ + +V + + GK + +D K L +VE + + Sbjct: 92 NRSAR-AVRAIGAAGGKVSAKMPSETRGKPVCSASDPIAGLDSAAKVALLNKVEAIAKAA 150 Query: 129 DKIKTSRFSYSDFVTRKIYL-NSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTV 187 D + +YL +G + P + +++ +A+ + + S GG Sbjct: 151 DPRIVQVMAGLTCEYDMVYLARLDGKHAADIRPMVRLNVTVIAKQGERREQ--GSAGGGG 208 Query: 188 GWELVESVDFNYWANFISS---KALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVE 244 ++L D N F+ + +AL+ L +R P+GEM +++ GV +HEA+GH +E Sbjct: 209 RYDLAY-FDENLVRQFVDAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLE 267 Query: 245 ADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLL 304 D R+G S+ SG IG+++ ++ +TV+D + G+ GS DDEG +R +I+DG+L+ Sbjct: 268 GDFNRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILV 327 Query: 305 NYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIG 364 Y+ D ++ G+GR +SYA P+ RM+NT++ G + EE+ + G+Y + Sbjct: 328 GYMQDETNARLTGTQSTGNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVN 387 Query: 365 DKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEF- 423 GGQVDI +G F+F A E + ++ G ++ V+ I GN + LK + +G D ++ Sbjct: 388 FGGGQVDITSGKFVFSASEAWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSG 447 Query: 424 PGFCGK-GQWVPVDDGGPHVLVKA--IVGG 450 G CGK GQ VPV G P + + A VGG Sbjct: 448 VGVCGKEGQSVPVGVGQPTLRIDAGLTVGG 477 >pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7227328|gb|AAF42385.1| (AE002556) tldD protein [Neisseria meningitidis MC58] Length = 480 Score = 191 bits (480), Expect = 1e-47 Identities = 122/447 (27%), Positives = 220/447 (48%), Gaps = 10/447 (2%) Query: 13 SNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKL 69 ++ V + DI + T Y + +E G V+ G+GVR + + +A + + + Sbjct: 32 AHHVDYADIYCQRTAYESWHLEEGIVKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDSI 91 Query: 70 EDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRR- 128 + + A++ + +V + + GK + +D K L +VE + + Sbjct: 92 NRSAR-AVRAIGAAGGKVSAKMPSETRGKPVCSASDPIAGLDSAAKVALLNKVEAIAKAA 150 Query: 129 DKIKTSRFSYSDFVTRKIYL-NSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTV 187 D + +YL +G + P + +++ +A+ + + GG Sbjct: 151 DPRIVQVMAGLTCEYDMVYLARLDGKHAADIRPMVRLNVTVIAKQGERREQGSAGGGGRY 210 Query: 188 GWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADS 247 + + + + +AL+ L +R P+GEM +++ GV +HEA+GH +E D Sbjct: 211 DLAYFDENLVHRFVDAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLEGDF 270 Query: 248 VRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYL 307 R+G S+ SG IG+++ ++ +TV+D + G+ GS DDEG +R +I+DG+L+ Y+ Sbjct: 271 NRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILVGYM 330 Query: 308 NDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKG 367 D ++ G+GR +SYA P+ RM+NT++ G + EE+ + G+Y + G Sbjct: 331 QDETNARLTGTQSTGNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVNFGG 390 Query: 368 GQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEF-PGF 426 GQVDI +G F+F A E + ++ G ++ V+ I GN + LK + +G D ++ G Sbjct: 391 GQVDITSGKFVFSASEAWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSGVGV 450 Query: 427 CGK-GQWVPVDDGGPHVLVKA--IVGG 450 CGK GQ VPV G P + + A VGG Sbjct: 451 CGKEGQSVPVGVGQPTLRIDAGLTVGG 477 >emb|CAC11942.1| (AL445065) conserved hypothetical protein [Thermoplasma acidophilum] Length = 455 Score = 185 bits (465), Expect = 9e-46 Identities = 127/453 (28%), Positives = 218/453 (48%), Gaps = 16/453 (3%) Query: 5 LRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING--WGFAS 62 L +++ ++ F D RF + NG+ + + + G +RV+ + + Sbjct: 2 LDRILDYAGSKSAFADARFMEIEGRGAVIRNGEFDESLYSNDSGYAIRVVNDSIAMAYVD 61 Query: 63 TNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEV 122 + D K+ + A+ L + +Y G + D L + + E Sbjct: 62 SEDWDKVRAVVDDAV-LRSRRPGKNRIYRGRSEKASWSEIGSDHVRDHSLGDMIAILKEA 120 Query: 123 EKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKS 182 + + ++ S + SD ++Y N++GS +E RI+F+ D + + Sbjct: 121 DSVAEEANVRIS--ALSDRFVHQVYENTDGSHVEGTYSRIFFNYLVGVSENDRYEQSSEE 178 Query: 183 FGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHA 242 FG T G++ + + S ++ A S G +I+ PE++G+ HE+ GH Sbjct: 179 FGWTGGYDAFDFKTISETMKNDVSNLREIILAPSVEPGNFDVIVGPEISGIVAHESAGHP 238 Query: 243 VEADSVRQGESILSG---MIGK----KIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRV 295 E D + E+ L+G + GK +IGSE+++VIDDPTL G +G Y+YDDEG+ ++ Sbjct: 239 TEYDRIAGREAALAGESFLTGKTFPYRIGSEKVSVIDDPTLKGSYGYYLYDDEGVRARKR 298 Query: 296 EIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEE 355 + ++G +L +RE++ + NG GR+ S+ PL RMS TYI PG+++ EE+FE Sbjct: 299 YLYRNGYTSEFLINRESAAWIGQESNGSGRSSSWDMEPLARMSTTYIEPGDYSFEELFEG 358 Query: 356 VKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAV 415 V G+Y+ +D + + KE Y I+ G+IK +VR + N + + AV Sbjct: 359 VHRGIYIKSFTEWNIDDIRFNERYVGKEAYYIENGDIKGRVRRPILETNTIKFYSAVDAV 418 Query: 416 GRDLKIEFPGFCGKG---QWVPVDDGGPHVLVK 445 G+DL G CGKG Q V V GGPH+ ++ Sbjct: 419 GKDLHFS-AGICGKGDPEQGVEVWMGGPHMRLR 450 >gb|AAK41402.1| Conserved hypothetical protein [Sulfolobus solfataricus] Length = 458 Score = 182 bits (458), Expect = 6e-45 Identities = 138/457 (30%), Positives = 227/457 (49%), Gaps = 22/457 (4%) Query: 4 ELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFAS 62 +L++L +K+ ++++R + NG++ G + G VR +G FAS Sbjct: 3 DLQSLYDKF--RYPYVEVRRHIVSTFGMSFLNGRLMGSFRFTDDGYSVRYYKDGVLYFAS 60 Query: 63 TNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEV 122 +N+ + L + K K+ E L P EG +K+ K F + ++EK + Sbjct: 61 SNNPNDLLSSNKEY----KIEGWESGLDNTEPKEGSYEVKEGKPFDLMSVDEKISFFKNL 116 Query: 123 EKMIRRDK-IKTSRFSYSDFVTRK-IYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW 180 + ++ + +K+ F Y + + K I +N GS I VPR+Y ++ V + T + Sbjct: 117 YEAVKDFRSVKSVSFFYDESIEEKEIIVN--GSRIVGRVPRLYVGMNLVLNENNRTATAF 174 Query: 181 KSFGGTVGWELVESVDFN-YWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEAL 239 GG+ G E++E ++ N + + S L +S +++ L G+ HE++ Sbjct: 175 YELGGSGGLEVLERMNLNEVVVDKVRSVTEVLAKGKSFGERTTDVVLSNMLTGIMAHESV 234 Query: 240 GHAVEADSV------RQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGK 293 GH EAD V + G S L+ + +IGS+ +TVIDDPT+P G Y DDEG+ + Sbjct: 235 GHPFEADRVLGREFAQAGLSYLAELKDNRIGSDVVTVIDDPTIPNSGGYYTTDDEGVEAR 294 Query: 294 RVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMF 353 +IKDG + YL +R +S N+ NG RA ++ PL+RMSNT+ PG T +E+ Sbjct: 295 PKYLIKDGKVNEYLQNRFSSSKFNVKSNGSARAANFDREPLIRMSNTFFKPGNMTFDELL 354 Query: 354 EEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIK 413 E+VK GVY+ +D + E Y IK G+I + V G + LK + Sbjct: 355 EDVKEGVYIKSYMEWNIDDMRLGQRYVGLEAYEIKNGKIGDPVLFPVFQGKTTELLKAVD 414 Query: 414 AVGRDLKIEFPGFCGKG---QWVPVDDGGPHVLVKAI 447 AV L + +PG CGKG Q +PV GGP++ ++ + Sbjct: 415 AVDNTL-VFYPGTCGKGDPDQGIPVWLGGPNMRLRNV 450 >pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment) Length = 313 Score = 173 bits (433), Expect = 5e-42 Identities = 105/314 (33%), Positives = 169/314 (53%), Gaps = 16/314 (5%) Query: 148 LNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVESVDFNYWANFISS- 206 L +G + P + ++S VA D ++ K +GG G+ +FN A+ ++ Sbjct: 2 LRPDGESYRDIRPLVRVNISVVAGQGDRQESGSKGYGGRAGY-----AEFNLRASNLART 56 Query: 207 ------KALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIG 260 +AL L + P+GEM +++ GV +HEA+GH +E D R+ S SG++G Sbjct: 57 PPTALREALVNLESIPAPAGEMDVVLGAGWPGVMLHEAVGHGLEGDFNRKRTSAFSGLMG 116 Query: 261 KKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVP 320 +++ ++ +TV+DD T+ + GS DDEG P R +I+DG+L+ Y+ DR+ ++ +N+ P Sbjct: 117 RQVAAKGVTVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGILVGYMQDRQNARLMNMKP 176 Query: 321 NGHGRAQSYAHVPLVRMSNTYIAPG-EWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMF 379 G+ A+ YAHVP+ RM+NTY+ G + + VK GGQVDI +G ++ Sbjct: 177 TGNAAARRYAHVPMPRMTNTYMLRGRSRSGRGVLASVKNAASRANFGGGQVDITSGKYVS 236 Query: 380 GAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFP-GFCGK-GQWVPVDD 437 E Y + G+ + GN L I+ +G DL ++ G CGK GQ VPV Sbjct: 237 QCTEAYKSENGKSGGPAEGRMLIGNGPTDLHRIRMIGNDLALDTGIGTCGKNGQGVPVGV 296 Query: 438 GGPHVLVKAI-VGG 450 G P +L++ I VGG Sbjct: 297 GQPSLLMERITVGG 310 >dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity of the cabon storage regulator (CsrA) [Bacillus halodurans] Length = 432 Score = 158 bits (395), Expect = 1e-37 Identities = 95/257 (36%), Positives = 136/257 (51%), Gaps = 8/257 (3%) Query: 192 VESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQG 251 V+ D + ++ A+ L AR PSG +I+ P A HE +GH +EAD Sbjct: 170 VQEEDLQELVLYTANAAMEKLDARPFPSGSYALILGPLAAPGIFHEVVGHGLEADIASIP 229 Query: 252 ESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRE 311 +S +G +G E++T+IDDPT G GSY DDEG ++ +I+ G ++NYL+ Sbjct: 230 QSAFHQRLGAMVGCEKVTIIDDPTKEGLPGSYSLDDEGTIAQQTTLIEKGRVVNYLSHLH 289 Query: 312 TSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVD 371 T NGHGR +Y H+PLVRMSNT++ PG EEM + + G+Y+ G V+ Sbjct: 290 TGHP----TNGHGRVINYQHLPLVRMSNTFLLPGTDDPEEMVSDTEVGLYVKKAINGDVN 345 Query: 372 IANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKI--EFPGFCGK 429 + G F EGY+I++G+I + + G+ L+ I VG D I E G CGK Sbjct: 346 MITGEFEIHVAEGYLIEKGQITSPILPTTLKGDGQKLLQSIDRVGNDFAIHSEVRGGCGK 405 Query: 430 -GQW-VPVDDGGPHVLV 444 GQ +PV G P V V Sbjct: 406 LGQSPLPVSAGSPTVRV 422 >sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|7429840|pir||S75512 hypothetical protein slr1322 - Synechocystis sp. (strain PCC 6803) >gi|1653157|dbj|BAA18073.1| (D90911) hypothetical protein [Synechocystis sp.] Length = 489 Score = 153 bits (383), Expect = 4e-36 Identities = 123/447 (27%), Positives = 196/447 (43%), Gaps = 15/447 (3%) Query: 18 FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN-GWGFASTNDLS------KLE 70 F++ E Y E+ + + G GVRV G + STND+S LE Sbjct: 45 FVEFFLEKVNYVSCLAEDDAITSLTPRLSSGCGVRVYKGKGDCYVSTNDISFNGLRTALE 104 Query: 71 DTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLD--VDLEEKTKLGLEVEKMIRR 128 + + + VP + A K+K +L ++E + + L + + Sbjct: 105 KGLSILGLTLPAGQSFVPELNLEMLRDYAGAKEKDQWLHRCSPMQEMSDILLGANQKLDH 164 Query: 129 --DKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGT 186 ++ R +Y + S+G+ + S + + K G T Sbjct: 165 YASHAQSRRAAYFRDWQEVLVAASDGTFARDIRLTQSVGFSLFCADGEHRTSIGKRSGDT 224 Query: 187 VGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246 + + + D A ++ A +L A SG PIIM + GV HEA GH +E Sbjct: 225 SNPDYLRTWDAETSAQEVAESAGKMLYADYVESGNYPIIMANQFGGVIFHEACGHLLETT 284 Query: 247 SVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNY 306 + + G+KI E LT D+ FG+ DDEG+P +R +I++G+L N+ Sbjct: 285 QIEHKTTPFLDKKGEKIAHENLTAWDEGLTDNAFGTIDMDDEGMPTQRTLLIENGILKNF 344 Query: 307 LNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDK 366 + DR S G GR QSYA+ RM NTYIAPG ++++++F V+ G+Y Sbjct: 345 IADRTGSIRTGHPRTGSGRRQSYAYAAASRMRNTYIAPGNYSVDDIFNSVEKGIYCKQMG 404 Query: 367 GGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGF 426 GG V A G F F E Y+++ G++ + ++ + G + + +I +DL + GF Sbjct: 405 GGSVG-ATGEFNFAVSEAYLVENGKLTKPLKGATLIGTATEIMNKISMSSQDLGLA-AGF 462 Query: 427 CGK-GQWVPVDDGGPHVLVKAI-VGGR 451 CG V V G PH+ V I VGGR Sbjct: 463 CGSVSGSVYVTVGQPHIKVDGITVGGR 489 >pir||E70461 pmbA protein - Aquifex aeolicus >gi|2984159|gb|AAC07693.1| (AE000761) peptide maturation [Aquifex aeolicus] Length = 441 Score = 144 bits (359), Expect = 2e-33 Identities = 117/466 (25%), Positives = 224/466 (47%), Gaps = 44/466 (9%) Query: 2 IDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GW 58 +D L NL++KY ++ FE + V N +VE V S+EE GIG+RVL + G+ Sbjct: 1 MDNLENLVKKYIKPGYEYEVFFERVKKLKIEVSNEQVENVSSSEERGIGIRVLKDKRLGF 60 Query: 59 GFASTNDLSKLEDTIKMAIKLAKVSNA-EVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTK 117 + S +++DT++ A+++ ++ E ++ KA+ ++ L + L+EK + Sbjct: 61 SYTSFLGEEEIKDTVEKAMEMCEIQEPDEANGFIEKLKPSKAVSVYDEESLSIPLQEKME 120 Query: 118 LGLEVEKMIRR-DK----IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARS 172 + +++EK + DK ++ S + +F R NS G + F + + Sbjct: 121 IPVKMEKYAKELDKRIVGVRKSTLTEVEFEVRSF--NSFG---------VEFGYRGTSYT 169 Query: 173 ADIMQTYWKSFGGTVGWEL-----VESVDFNYWANFISSKALSLLSARSPPSGEMPIIMD 227 + I ++ + WE ++++++ K ++LL + MP++ Sbjct: 170 SMIATLGTENDDSAISWEFRGARRLKNLNWKSMVEDAVFKTVNLLHPSPFETRSMPVVFF 229 Query: 228 PELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDD 287 E + + +A D + +G+++L + + + SE++T++DD ++ F ++ YD Sbjct: 230 RESFAMLL-DAFSPMFLGDYLVKGKTLLKDKVNEIVASEKITLVDDGSMEEGFSTFPYDA 288 Query: 288 EGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEW 347 EG+P ++ +I GV +L+ T++ + P G+ SY +P +N Y+ G Sbjct: 289 EGVPTRKNLLIDKGVFKGFLHSLYTARKSSQEPTGNSVRGSYKELPSSGTTNFYLEKGNL 348 Query: 348 TLEEM---FEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGN 404 + EE+ ++EV + ++G VD +G F G G + K+G+ + VR + ++GN Sbjct: 349 SFEELLSYYDEVFLVLEVMGLH--TVDTISGDFSLGC-SGILYKKGKKDKTVRGITVAGN 405 Query: 405 ILDTLKEIKAVGRDLKIEFPGFCGKGQWVPVDDGGPHVLVKAIVGG 450 ILD LK ++ VG DL F G G P VLVK + G Sbjct: 406 ILDLLKNVEEVGNDLT-----FYG-------SVGSPSVLVKKLTLG 439 >pir||B83330 hypothetical protein PA2529 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9948585|gb|AAG05917.1|AE004680_5 (AE004680) hypothetical protein [Pseudomonas aeruginosa] Length = 477 Score = 136 bits (340), Expect = 4e-31 Identities = 125/456 (27%), Positives = 213/456 (46%), Gaps = 30/456 (6%) Query: 1 MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW-G 59 MID L++ + +F +R+ +V E +++ G + V +NG Sbjct: 1 MIDPLKHRFAALRSRAEFHSLRYVQRSGEYLSVRRNVSEPPHFSQDRGAMLCVRLNGVEA 60 Query: 60 FASTNDLSK------LEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQ-KKDFLDVDL 112 +A+TNDLS LE + A ++A+ + +V P G++ + +D L Sbjct: 61 YAATNDLSAAGLQAALEQAERQAERIARHALFDVRGLP--PASGRSQYRSPNQDAPFPSL 118 Query: 113 EEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTRK--IYLNSEGSVIETVVPRIYFSLSAVA 170 E +L E + RD+ + +S V+R+ +YLNS G+ +Y S A Sbjct: 119 AECYELLAEESAKVPRDE-RLVNWSVFLEVSRQEQLYLNSAGAEQYHEQRFVYPGASVTA 177 Query: 171 RSADIMQTYWKSFGG-----TVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPII 225 QT +SFGG G E++E + A I+ +AL LL+A + PSG ++ Sbjct: 178 YDGHDSQT--RSFGGHHAGQQGGAEVIERLGLVGAAPRIADQALQLLAAPNTPSGRCDLL 235 Query: 226 MDPELAGVFIHEALGHAVEADSVRQGESILSGM-------IGK-KIGSEELTVIDDPTLP 277 + P+ + IHE++GH +E D + E +G G+ + GS L V DP +P Sbjct: 236 LMPDQMILQIHESIGHPLELDRILGDERNYAGTSFIKTEDFGRYQYGSSLLNVSFDPEIP 295 Query: 278 GKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRM 337 + SY DD+G P ++ +I++G LL L + L + RA S+ P+ RM Sbjct: 296 EELASYRQDDDGSPARKEYLIREGRLLRPLGGALSQHRSGLEGVANSRASSWNRAPIDRM 355 Query: 338 SNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVR 397 +N + PG+ + ++ ++ GV M ++ +D A F FG + G +I++GE+K V+ Sbjct: 356 ANLNLEPGDKSFAQLVAGIERGVLMSYNRSWSIDDARNKFQFGCEWGQLIEDGELKGVVK 415 Query: 398 DVGISGNILDTLKEIKAVGRDLKIEFPG--FCGKGQ 431 + G + + AVG E G +CGKG+ Sbjct: 416 NPNYRGISAQFWRNLSAVGDAGTFEVLGTPYCGKGE 451 >pir||E72342 pmbA-related protein - Thermotoga maritima (strain MSB8) >gi|4981252|gb|AAD35809.1|AE001743_11 (AE001743) pmbA-related protein [Thermotoga maritima] Length = 435 Score = 133 bits (331), Expect = 4e-30 Identities = 111/428 (25%), Positives = 206/428 (47%), Gaps = 28/428 (6%) Query: 3 DELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFA 61 D L L +K EV+ I F T + NG ++ + + ++VL +G G Sbjct: 8 DRLFALAKKNGVEVQ---ISFLETREFSLRLANGDLDQYTDAGKFNVEIKVLKDGKTGTF 64 Query: 62 STNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLD----VDLEEKTK 117 T L E + A+ +V ++E Y EG ++ + ++ + ++EK Sbjct: 65 RTQVLENPEKCFEEALSNLQVKDSEEKEYF---FEGGKEYREMETYVGRFEKLSVKEKMD 121 Query: 118 LGLEVEKMIRRDK--IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADI 175 + + + +D+ + Y D V +KI N+ G +E+ + + A+AR A+ Sbjct: 122 MAKKAHESAAKDERVVMVPTVMYKDMVIKKIITNTLGLDVESQMDGGFLFAMAIARDANP 181 Query: 176 MQTYWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFI 235 W T E ++ + +A+SL+ +++ PSG+ P++M A + + Sbjct: 182 RSGSWYELARTP-----EDLNPEEIGKRAAEEAISLIGSKTIPSGKYPVLMR-NTALLDL 235 Query: 236 HEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRV 295 E + A++V++ S L G +G+++G+ +++ D P P S +DDEG+P Sbjct: 236 MEMFIPMISAENVQKNLSPLKGKLGEQVGNPAVSIKDLPYHPKGLSSTPFDDEGVPTTEK 295 Query: 296 EIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEE 355 ++++GVL +L++ +T++ + P G+G V +R N + PGE + EE+ +E Sbjct: 296 FVLENGVLKTFLHNLKTARKEGVEPTGNG------FVGGIRPVNLMLMPGEKSFEELLKE 349 Query: 356 VKFGVYMIGDKG--GQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIK 413 + GV + +G + +G F AK GY ++ GEI V D+ ISGN LD L++I Sbjct: 350 MDRGVVITEVEGMHAGANSISGEFSLFAK-GYWVENGEIAHGVEDITISGNFLDLLRKIV 408 Query: 414 AVGRDLKI 421 VG D+K+ Sbjct: 409 LVGNDVKV 416 >pir||D70703 tldD homolog Rv2315c - Mycobacterium tuberculosis (strain H37RV) >gi|1524285|emb|CAB02052.1| (Z79702) hypothetical protein Rv2315c [Mycobacterium tuberculosis] Length = 505 Score = 125 bits (312), Expect = 7e-28 Identities = 122/461 (26%), Positives = 203/461 (43%), Gaps = 35/461 (7%) Query: 20 DIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSK--LEDTIKMA 76 D+R + +G++E + E+G+ VRV++ G WGFAS +L+ T + A Sbjct: 36 DLRVHRISTEIIQLRDGELETAVISRELGLAVRVIVAGTWGFASHAELAPDVAAATARHA 95 Query: 77 IKLAKVS---NAEVPLYVGNPV--EGKAIIKQKKDFLDVDLEEKTKLGLEVE-KMIRRDK 130 + +A V N E PV + + + + D V EK + + +++ D Sbjct: 96 VHVATVLAALNTERVRLAPEPVYTDAEWVSNYRIDPFGVPASEKIAVLRDYSGRLLDADG 155 Query: 131 IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSA-----DIMQTYWKSFGG 185 I S + + Y ++ GS I R+ L AVA + + M+T Sbjct: 156 IDHVSASLNAVKEQTFYADTFGSSITQQRVRLLPCLDAVAVDSAAGNFESMRTLAPPTAR 215 Query: 186 TVGWELVESVDFNYWANFISSKALSLLSARSPPS---GEMPIIMDPELAGVFIHEALGHA 242 GWE+V + W + ++ L PS G +++DP + IHE++GHA Sbjct: 216 --GWEVVAGDEIWNWTDELAQLPSLLAEKVRAPSVMPGPTDLVIDPTNLWLTIHESIGHA 273 Query: 243 VEADSVRQGESILSGM-------IGK-KIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKR 294 E D E+ +G +G + GS + V D T + YDDEG+ + Sbjct: 274 TEYDRAIGYEAAYAGTSFATPDKLGTLRYGSPVMNVTADRTAEFGLATVGYDDEGVAAQS 333 Query: 295 VEIIKDGVLLNYLNDRETSKALNLV-PNGHGRAQSYAHVPLVRMSNTYIAPG--EWTLEE 351 ++++DGV + Y DR + L NG A S HVP+ RM+N + PG + + + Sbjct: 334 WDLVRDGVFVGYQLDRAFAPRLGEPRSNGCSYADSPHHVPIQRMANISLQPGIEDLSTAD 393 Query: 352 MFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKE 411 + V G+Y++GDK +D+ +F F + + I+ G++ Q+RDV + D Sbjct: 394 LIGRVDDGIYIVGDKSWSIDMQRYNFQFTGQRFFRIRGGQLYGQLRDVAYQSSTTDFWNA 453 Query: 412 IKAVGRDLKIEFPGF--CGK---GQWVPVDDGGPHVLVKAI 447 ++AVG G CGK GQ V G P L + + Sbjct: 454 MEAVGGPSTWRMGGAINCGKAQPGQVAAVSHGCPSALFRGV 494 >pir||T36780 hypothetical protein SCI28.10 - Streptomyces coelicolor (fragment) >gi|5525068|emb|CAB50884.1| (AL096844) hypothetical protein [Streptomyces coelicolor A3(2)] Length = 435 Score = 116 bits (287), Expect = 6e-25 Identities = 110/405 (27%), Positives = 184/405 (45%), Gaps = 38/405 (9%) Query: 20 DIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTIKMA-- 76 D R E + + + + G ++G VRV+ G WGFAS DL+ L+ K+A Sbjct: 34 DFRLERVRNASWRLRDARPAGSSDTTDLGYAVRVVHGGTWGFASGVDLT-LDAAAKVASQ 92 Query: 77 -IKLAKVSNAEVPLYVGN---------PVEG-KAIIKQKK--DFLDVDLEEKTKLGLEVE 123 + +AK+S A+V G+ PV K+ I + F D ++ L Sbjct: 93 AVAMAKLS-AQVIKAAGSDERVELAAEPVHADKSWISAYEIDPFSVPDADKAALLADWSA 151 Query: 124 KMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVA-----RSADIMQT 178 +++ D + S K Y ++ G+V R++ L+AV+ D M+T Sbjct: 152 RLLAADGVDHVDASLLTVHENKFYADTAGTVTTQQRVRLHPVLTAVSVDDSSGEFDSMRT 211 Query: 179 YWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPP--SGEMPIIMDPELAGVFIH 236 G GWE + +++ + L R+P +G +++DP + IH Sbjct: 212 LAPPAGR--GWEYLTGTGWDWDSELAEIPELLAEKMRAPSVEAGLYDLVVDPSNLWLTIH 269 Query: 237 EALGHAVEADSVRQGESILSG-------MIGK-KIGSEELTVIDDPTLPGKFGSYVYDDE 288 E++GHA E D E+ +G +GK + GSE + V D T + YDDE Sbjct: 270 ESIGHATELDRALGYEAAYAGTSFATFDQLGKLRYGSELMNVTGDRTAEHGLATVGYDDE 329 Query: 289 GLPGKRVEIIKDGVLLNYLNDRETSKALNLV-PNGHGRAQSYAHVPLVRMSNTYIA--PG 345 G+ G+ +++KDG L+ Y DR ++ NG A S AHVP+ RM+N + PG Sbjct: 330 GVEGQSWDLVKDGTLVGYQLDRRIARLTGFERSNGCAYADSPAHVPVQRMANVSLLPDPG 389 Query: 346 EWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEG 390 + E++ V G+Y++GD+ +D+ +F F + + I+ G Sbjct: 390 GLSTEDLIGGVDRGIYVVGDRSWSIDMQRYNFQFTGQRFFRIENG 434 >gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis] Length = 448 Score = 113 bits (280), Expect = 4e-24 Identities = 106/407 (26%), Positives = 185/407 (45%), Gaps = 26/407 (6%) Query: 20 DIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWGFA-STNDLSK--LEDTIKMA 76 D+ F + +V G++E V +E IG+R+ I + S++D SK L+ ++ A Sbjct: 27 DVVFVQGQSQDISVRLGQLEDVGRSEGAEIGLRLFIGHRSASVSSSDFSKEALDALVERA 86 Query: 77 IKLAKVSNAEVPLYVGNP-----VEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKI 131 + +A+ A + G ++G A + D ++ +L L+ E R Sbjct: 87 VAMAR--EAPEDRWAGLAPKELLMQGTAPEIESDDGKEIAPAVLRELALKAEDAARSVDG 144 Query: 132 KTSRFSYSDFVTRKIYL--NSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGW 189 T+ S R I+ SEG + S +A MQ + F T + Sbjct: 145 ITNSEGASASAGRTIFALATSEGFTRGSSSSSYGCSACVIAGQGVNMQRDY-DFHATRYF 203 Query: 190 ELVESVDFNYWANFISSKALSLLSARSPP----SGEMPIIMDPELAGVFIHEALGHAVEA 245 E +++ A I ++A AR P SG+MPII DP + F+ + + Sbjct: 204 EDLDA------AELIGTRAAERTIARLNPTRIDSGQMPIIFDPRVGSGFLSYLI-QGISG 256 Query: 246 DSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLN 305 ++ + S L +GK + +E +T+ +DP S +D EGLP K II G L Sbjct: 257 GAITRKTSFLLDSLGKPVFNEGITIKEDPWRKRGIASRAFDGEGLPTKPNNIIDKGRLNG 316 Query: 306 YLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGD 365 +L D ++ L + P GH R + P +N Y+ G+ T EE+ ++K G+Y+ Sbjct: 317 WLLDSAAARQLGMTPTGHAR-RGVGGPPSTGTANLYLEAGKVTPEELMSDIKLGIYVTEM 375 Query: 366 KGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEI 412 G V++ G + GA G+II++G++ E V ++ ++GN+ D ++ Sbjct: 376 IGSGVNMITGDYSRGA-SGFIIRDGQLAEPVAEITVAGNLKDIFMQM 421 >pir||B71249 hypothetical protein PH0249 - Pyrococcus horikoshii >gi|3256638|dbj|BAA29321.1| (AP000001) 426aa long hypothetical protein [Pyrococcus horikoshii] Length = 426 Score = 111 bits (276), Expect = 1e-23 Identities = 120/436 (27%), Positives = 198/436 (44%), Gaps = 54/436 (12%) Query: 9 IEKYSNEVKFMDIRFENTIYTEFT---------VENGKVEGVESNEEVGIGVRVLING-- 57 +EK +K D+ +E IY E + ++E GIG+R+L+ G Sbjct: 6 VEKLVKILKSFDVEWE--IYWESASSLSLKFRKIRRAEIERSTYRVSSGIGLRILVGGKI 63 Query: 58 -WGFASTNDLSK--LEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQ---KKDFLDVD 111 + + S +D SK LE +K A+K+AK+S E P + PV GK + K +D+ Sbjct: 64 GFSYLSGSDFSKDELELLVKRALKIAKISGTEYPAF---PVPGKYPSIRGLYDKRIVDLS 120 Query: 112 LEEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTR---KIYLNSEGSVIETVVPRIYFSLSA 168 +E+ + G E+ + F + T + +NS G +E R +L Sbjct: 121 IEDLSYYGTEL--------VNIEVFGEASIGTSTGIRGIMNSNG--VEGSENRSLLTLGL 170 Query: 169 VA-RSADIMQTYWKSFGGTVGWE-LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIM 226 A +Y KSF E +VE + F S+ A+ E II+ Sbjct: 171 YAYEKGKGSGSYGKSFRVLPDMEKVVEEIKETAMFEFKLSR-----EAKKIEKYEGEIII 225 Query: 227 DPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYD 286 +P+ F+ + + V A SV S +G ++ SE ++IDDPT+ GSY +D Sbjct: 226 EPKALISFLSIFVPN-VSAKSVYMKRSRFE-RLGVEVSSESFSIIDDPTIDEGLGSYSFD 283 Query: 287 DEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGE 346 EG PG R IIKDGVL ++L+D++ L + G+ +SY+ P++ SN I G Sbjct: 284 GEGNPGMRKFIIKDGVLTSFLSDQKYGSLLGIGSTGNA-IRSYSSQPIIDSSNLLIPSGN 342 Query: 347 WTLEEMFEEVKFGVYMIGDKGGQ-VDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNI 405 TL+E G+++ G + G F + GYI+ +K ++ I GNI Sbjct: 343 ETLDE-------GIFIRSVYGEHTANPITGDFSLNIELGYIVNNRGVKPFKGNM-IVGNI 394 Query: 406 LDTLKEIKAVGRDLKI 421 + LK + ++ ++++I Sbjct: 395 FEMLKNVTSIDKNVEI 410 >pir||B69009 conserved hypothetical protein MTH1070 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622168|gb|AAB85559.1| (AE000877) conserved protein [Methanobacterium thermoautotrophicum] Length = 430 Score = 110 bits (273), Expect = 3e-23 Identities = 96/414 (23%), Positives = 190/414 (45%), Gaps = 33/414 (7%) Query: 8 LIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDL 66 + E Y K +++ + + ++ GK+E + GIG+R+L G GFA T+D Sbjct: 18 MAEVYIEREKTLEVEIQRDL-----IDFGKIESM-----TGIGIRILKEGRMGFAYTSDP 67 Query: 67 SKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIK-QKKDFLDVDLEEKTKLGLEVEKM 125 ++ ++MA + ++++ + P ++ + F D+++E+ ++ + Sbjct: 68 DGVDVAVRMAAQNLQLADPDENFGFSEPSTYPSVKGIHDRSFDDLEVEDSVEMAGRMINR 127 Query: 126 IRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGG 185 + + K + ++ LNSEG + S S+ SA I T ++ Sbjct: 128 VLEEGCKPTSGGFTASRIETFILNSEG---------VEESSSSTGFSAHISVTAGENGMK 178 Query: 186 TVGWELVESVDFNYWANFISSKALSL----LSARSPPSGEMPIIMDPELAGVFIHEALGH 241 T +E S + +++ +A + + RS SG +P ++D A + G Sbjct: 179 TTAYESDSSCKLDINPEWVAGRACRIARDSMGGRSIESGRIPAVLDYHAAAGLLGTFAG- 237 Query: 242 AVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDG 301 A AD+V++G S+L+ IG ++ E L+V DD TL G GS +D EG P +R +++DG Sbjct: 238 AFSADNVQRGRSVLADRIGSQVTGEGLSVYDDGTLEGGLGSAPFDGEGTPSQRTALVEDG 297 Query: 302 VLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVY 361 +L Y+++ T+ G+G + Y VP V +N + E+ ++ + G++ Sbjct: 298 ILRGYMHNIYTASKGRADSTGNG-LRGYMEVPAVSTTNFIL---EFDSTVPLDDFR-GIF 352 Query: 362 MIGDKGGQ-VDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKA 414 + G + +G F A ++ GE V+ +SGNI + + ++ + Sbjct: 353 VTDVLGAHTANPISGDFSVEANNAFMADSGEF-TPVKKAMLSGNIFELMMKVSS 405 >sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||S13730 pmbA protein - Escherichia coli >gi|42440|emb|CAA38091.1| (X54152) pmbA is involved in the production of antibiotic MccB17 [Escherichia coli] >gi|537077|gb|AAA97132.1| (U14003) pmbA gene product [Escherichia coli] >gi|1732440|dbj|BAA07915.1| (D44452) TldE protein [Escherichia coli] >gi|1790682|gb|AAC77192.1| (AE000494) maturation of antibiotic MccB17, see tld genes [Escherichia coli K12] Length = 450 Score = 102 bits (253), Expect = 6e-21 Identities = 110/430 (25%), Positives = 192/430 (44%), Gaps = 27/430 (6%) Query: 9 IEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLI-NGWGFASTNDLS 67 +E S + ++ T + G+VE VE N + +G+ V N G AS+ DLS Sbjct: 26 LELASGKSDGAEVAVSKTTGISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLS 85 Query: 68 K--LEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFL---DVDLEEKTKLGLEV 122 + T++ A+ +A+ ++ + V + E A D +V +E +L Sbjct: 86 PQAIARTVQAALDIARYTSPDPCAGVADK-ELLAFDAPDLDLFHPAEVSPDEAIELAARA 144 Query: 123 EKM-IRRDK--IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTY 179 E+ ++ DK T S++ K++ NS G + R S +A M+ Sbjct: 145 EQAALQADKRITNTEGGSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDME-- 202 Query: 180 WKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELA-GVFIHEA 238 + + T+G + + + + + LS LS R + + P+I E+A G+F H Sbjct: 203 -RDYAYTIGRAMSDLQTPEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGH-- 259 Query: 239 LGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298 L A+ SV + + L +GK+I + LT+ + P L S +D EG+ +R +II Sbjct: 260 LVGAIAGGSVYRKSTFLLDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDII 319 Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358 KDG+L +L +++ L L GH + N IA + E+M +E+ Sbjct: 320 KDGILTQWLLTSYSARKLGLKSTGHAGG----------IHNWRIAGQGLSFEQMLKEMGT 369 Query: 359 GVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418 G+ + G V G + GA G+ ++ GEI+ V ++ I+GN+ D + I VG D Sbjct: 370 GLVVTELMGQGVSAITGDYSRGA-AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGND 428 Query: 419 LKIEFPGFCG 428 ++ CG Sbjct: 429 IETRSNIQCG 438 >pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus abyssi (strain Orsay) >gi|5457662|emb|CAB49153.1| (AJ248283) PMBA PROTEIN (TLDE PROTEIN) [Pyrococcus abyssi] Length = 427 Score = 100 bits (247), Expect = 3e-20 Identities = 112/400 (28%), Positives = 190/400 (47%), Gaps = 43/400 (10%) Query: 37 KVEGVESNEEV--GIGVRVLING---WGFASTNDLSK--LEDTIKMAIKLAKVSNAEVPL 89 KVE + EV GIG+RVL G + + S ++ ++ LE +K A K+AKV+ + + Sbjct: 40 KVEVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGS---I 96 Query: 90 YVGNPVEGK-----AIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTR 144 Y G PV K + K ++ EE + G E+ D + S + Sbjct: 97 YPGFPVPKKFPNVRGLYDDK--IRNLSTEEIVEYGTELV-----DVPPNAEASIGLSTSE 149 Query: 145 KIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWEL-VESV-DFNYWAN 202 + +NS G+ + F L +S +Y KSF E +E V + W Sbjct: 150 RGIMNSNGTEGREERTLLAFGLYVFEKSKGT-GSYSKSFRRLPKLESEIEGVREKALWEF 208 Query: 203 FISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKK 262 +SSKA L +GE II++P+ + L + V A +V S + + G + Sbjct: 209 EMSSKARKL----EKYNGE--IILEPKAVASILSIFLPN-VSARNVYLKRSRFTEL-GIE 260 Query: 263 IGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNG 322 + S LT+IDDPT+ G SY +D EG PG R IIK+G+L ++L D++ + + G Sbjct: 261 VASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTG 320 Query: 323 HGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQ-VDIANGSFMFGA 381 + ++ Y+ P + SN I+PG +E G+++ G G + +G F Sbjct: 321 NA-SRGYSSQPSISPSNIMISPGN-------DEQDEGIFIRGIYGEHTANSVSGDFSLNV 372 Query: 382 KEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKI 421 GY+++ GEI+ ++ + GN+ + LK + +G++++I Sbjct: 373 DLGYVVRGGEIRPFKGNM-LVGNVFEMLKNVTNIGKEIEI 411 >pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (strain PCC 6803) >gi|1652621|dbj|BAA17541.1| (D90907) PmbA protein [Synechocystis sp.] Length = 427 Score = 99.1 bits (243), Expect = 9e-20 Identities = 97/394 (24%), Positives = 180/394 (45%), Gaps = 31/394 (7%) Query: 34 ENGKVEGVESNEEVGIGVRVLINGW-GFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVG 92 E +++ +ES+E G+ +R+ NG G A + E ++ A+ LA ++ P + Sbjct: 35 EANRLKQLESSESEGVALRLWKNGQAGLAVAYGPVEPEILVEKALALAALNPPNPPRFTA 94 Query: 93 NPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIK---TSRFSYSDFVTRKIYLN 149 + + + + DV +E+ G +R + + + + S TR I N Sbjct: 95 PRQDYRESLGE-----DVSVEQLIDWGQTAIASLRSEFAEVLCSGELACSTDSTRLI--N 147 Query: 150 SEGSVIETVVPRI--YFSLSAVARSADIMQTY--WKSFGGTVGWELVESVDFNYWANFIS 205 SEG + YF + + R D + Y + G T ++VE+ + Sbjct: 148 SEGLDCTWTERSLSYYFGVEWI-RGEDFLAIYDGEQCRGQTNVGQVVEN---------LR 197 Query: 206 SKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGS 265 + L + + G+MPI++ A + + + +G A+ V + S + +G+ + Sbjct: 198 QRLLWVEVNQQIQGGKMPILLTSGAASL-LWDTVGEALHGQRVAEDSSPWAEKLGQTVAI 256 Query: 266 EELTVIDDPT-LPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHG 324 EEL + DPT +P +DDEG +++ +IK+G + + D ET++ L G+G Sbjct: 257 EELNISQDPTAIPF---DCPFDDEGSRTQKLALIKNGKIAQFYTDHETAEKLGTTTTGNG 313 Query: 325 RAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEG 384 S P + N I PG + +++ +++ G+ + GG DI +G F G Sbjct: 314 FRPSLGSAPQPGLVNMLITPGTASFDQLLKKLGNGLVVDQILGGGADI-SGDFSINVDLG 372 Query: 385 YIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418 Y ++ GEI +V+D +SGNI + L +I A+G D Sbjct: 373 YRVQNGEITGRVKDTMVSGNIYELLNQIIALGSD 406 >pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657118|gb|AAF95676.1| (AE004322) pmbA protein [Vibrio cholerae] Length = 447 Score = 96.7 bits (237), Expect = 5e-19 Identities = 102/401 (25%), Positives = 183/401 (45%), Gaps = 40/401 (9%) Query: 37 KVEGVESNEEVGIGVRVLINGW-GFASTNDLSK--LEDTIKMAIKLAKVSNAEVPLYVGN 93 +VE VE N + +G+ V G AST+DLS+ + T+ A+ +A+ ++A+ Y G Sbjct: 50 EVENVEFNSDGALGITVYRGQRKGSASTSDLSEKAIRQTVLAALDIAQYTSADP--YAG- 106 Query: 94 PVEGKAIIKQKKDFLDV--------DLEEKTKLGLEVEKMIRRDKIKTSRF-SYSDFVTR 144 P + ++++ D LD+ D+ + + E + KIK S SY Sbjct: 107 PAPKELMVQEIPD-LDLFHPDEPNPDVAAQIAIAAERAALGYSKKIKQSDGGSYDSHYGV 165 Query: 145 KIYLNSEGSVIETVVPRIYFSLSAVA--RSADIMQTYWKSFGGTVG--WELVESVDFNYW 200 ++Y NS G + R S S + R+ ++ + Y + W ESV Sbjct: 166 RVYGNSHGLLASYASSRHSISCSVIGEGRNGEMERDYSYTVARHRDDLWT-PESVGLQAA 224 Query: 201 ANFISSKALSLLSARSPPSGEMPIIMDPELA-GVFIHEALGHAVEADSVRQGESILSGMI 259 N +S L + +G+ P++ ++A G+ H + A+ ++ + S L + Sbjct: 225 ENTVSR-----LDPQKLKTGQFPVMFAADVATGLIGHLVM--AISGGNLYRKSSFLLDHL 277 Query: 260 GKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLV 319 GK I + + P + S +D EG+ + +EII DGVL YL ++ +N+ Sbjct: 278 GKTILPTWFNISERPHVMRGLASSPFDSEGVRTQDLEIITDGVLATYLLTSYAARKMNMT 337 Query: 320 PNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMF 379 P GH + N Y+ ++M +E+ G+ + G V++ G + Sbjct: 338 PTGHAGG----------IHNWYVKSTGQNYQQMLKELGTGLLVTEVMGQGVNVVTGDYSR 387 Query: 380 GAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420 GA G+ ++ GEIK V ++ I+GN+ L++I AVG D++ Sbjct: 388 GA-AGFWVENGEIKYPVSEITIAGNLKQMLQQIVAVGSDIE 427 >sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C64186 pmbA protein - Haemophilus influenzae (strain Rd KW20) >gi|1574709|gb|AAC22807.1| (U32795) pmbA protein (pmbA) [Haemophilus influenzae Rd] Length = 451 Score = 96.3 bits (236), Expect = 6e-19 Identities = 94/393 (23%), Positives = 190/393 (47%), Gaps = 24/393 (6%) Query: 37 KVEGVESNEEVGIGVRVLINGW-GFASTNDLSK--LEDTIKMAIKLAKVSNAE--VPLYV 91 ++E VE + +G+ V + G AST+DLS+ +++ ++ A+ +AK ++ + L Sbjct: 54 EIENVEFTNDGALGISVYMGQQKGNASTSDLSESAIKNAVEAALAIAKYTSPDDCTGLAD 113 Query: 92 GNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKM-IRRDK--IKTSRFSYSDFVTRKIYL 148 + + A + D+D+++ T+L L+ E+ ++ D+ I ++ S++ K+Y Sbjct: 114 KDLMAFDAPDLELYHAADIDVDKATELALQAEQAALQADERIINSNGASFNSHTGVKVYG 173 Query: 149 NSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVESVDFNYWANFISSKA 208 NS G + + R S S + D ++ ++ T+ E + + + K Sbjct: 174 NSHGMLQSYLSSRYSLSCSVIGGVEDALENDYEY---TISREFDKLQSPIWVGENCAKKV 230 Query: 209 LSLLSARSPPSGEMPIIMDPELA-GVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEE 267 +S L+ + + E+P+I ++A G+ H A A+ S+ + S L +GK++ + Sbjct: 231 VSRLNPQKLSTREVPVIFLNDVATGIISHFAA--AISGGSLYRKSSFLLDHLGKQVLPDW 288 Query: 268 LTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQ 327 ++ + P L + S +D EG+ + EI+++G+L YL + K L + GH Sbjct: 289 FSISERPHLLRRLASTPFDSEGVRTQDREIVENGILQTYLVTSYSGKKLGMSSTGHAGG- 347 Query: 328 SYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYII 387 H LV+ + T L + ++ G+ + G V+I G + GA G+ + Sbjct: 348 --IHNWLVKPNLT------GGLTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGA-SGFWV 398 Query: 388 KEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420 + GEI+ V ++ I+G + D LK + AV D++ Sbjct: 399 ENGEIQYPVAEITIAGQLQDMLKNMLAVADDIE 431 >pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950709|gb|AAG07860.1|AE004861_1 (AE004861) PmbA protein [Pseudomonas aeruginosa] Length = 449 Score = 94.0 bits (230), Expect = 3e-18 Identities = 95/406 (23%), Positives = 180/406 (43%), Gaps = 41/406 (10%) Query: 32 TVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKLEDTIKMAIKLAKVSNAEVP 88 +V G+VE VE N + G G+ + G S + + +T+ A+ +A+ ++ + Sbjct: 48 SVRQGEVETVEFNRDQGFGITLYAGQRKGSASTSATGEAAIRETVAAALAIARHTSEDEC 107 Query: 89 LYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTR---- 144 + + ++ ++DL L E + + R + + F+ VT+ Sbjct: 108 AGLADAA------LMARELPELDLYHPWSLSPE-QAVERALACEAAAFAADKRVTKADGT 160 Query: 145 --------KIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT-YWKSFGGTVGWELVESV 195 ++Y NS G + R S +A MQ YW G L + Sbjct: 161 TLNTHQGCRVYGNSHGFIGGYASTRHSLSCVMIAEGEGQMQRDYWYDVNRR-GEALASAE 219 Query: 196 DFNYWANFISSKALSLLSARSPPSGEMPIIMDPELA-GVFIHEALGHAVEADSVRQGESI 254 A + +A S L AR + E+P++ PE+A G+F H LG A+ S+ + S Sbjct: 220 SIGRRA---AERAASRLGARPVQTAEVPVLFAPEIAVGLFGH-FLG-AISGGSLYRKSSF 274 Query: 255 LSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSK 314 L G +G+++ E L++ + P L G GS +D +GL +++G L++Y+ + + Sbjct: 275 LEGALGQRLFPEWLSIDERPHLVGALGSASFDSDGLATYAKPFVENGELVSYVLGTYSGR 334 Query: 315 ALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIAN 374 L L + + N +++ G+ + ++ G+ + G V++ Sbjct: 335 KLGLPSTANAGG----------VHNLFVSHGDEDQAALIRRMERGLLVTELMGQGVNLVT 384 Query: 375 GSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420 G + GA GY ++ GEI+ V++V I+ N+ D + I AVG+D++ Sbjct: 385 GDYSRGAA-GYWVENGEIQFPVQEVTIAANLRDLFRRIVAVGKDIE 429 >sp|P57191|PMBA_BUCAI PMBA PROTEIN HOMOLOG >gi|10038774|dbj|BAB12809.1| (AP001118) pmbA protein [Buchnera sp. APS] Length = 446 Score = 92.8 bits (227), Expect = 7e-18 Identities = 97/429 (22%), Positives = 197/429 (45%), Gaps = 27/429 (6%) Query: 1 MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN-GWG 59 +++ ++N ++ N +++ + TI V N VE VE N + G+ + V G Sbjct: 14 LVNTVKNTLKLSKNINASVEVFIKKTIGISVNVRNNVVENVEFNSDGGLFITVYNKFSKG 73 Query: 60 FASTNDLS--KLEDTIKMAIKLAKVSNAEVPLYVGNP-VEGKAIIKQKKDFL---DVDLE 113 S+ D S +++ + +AI ++K S+++ + G P ++ + D + ++E Sbjct: 74 SVSSKDFSIKNIKNMLDIAINISKYSSSD--FFSGLPDIKFLCFHSMELDLFHPWEFNIE 131 Query: 114 EKTKLGLEVEKM-IRRDK-IKTSRFSY-SDFVTRKIYLNSEGSVIETVVPRIYFSLSAVA 170 K+ + EK DK I S S+ + T ++ NS G + + R +A Sbjct: 132 NAIKMSILSEKSAFESDKRIVNSEGSFLNSHTTINVFGNSLGVLEKYKSTRYSNYTCMIA 191 Query: 171 RSADIMQTYWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPEL 230 + + MQ + F ++ + + + + +A+S L +R + PII E+ Sbjct: 192 KDKNSMQ---RDFDYSLSRRIDDLIKPEILGQKTAKRAISRLGSRKIQTMRSPIIFSSEI 248 Query: 231 AGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGL 290 + +F L A+ D+V Q + L + KI + L + ++P L GS +D+EG+ Sbjct: 249 SHMFFSH-LASAISGDNVYQKSTFLINDLKMKIFPDWLDIEENPHLKRGLGSKPFDNEGV 307 Query: 291 PGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLE 350 + IIK G+L +L + ++ L L G+ + N ++ + E Sbjct: 308 ATEIKYIIKAGILQTWLLNCYNARKLKLDSTGNCGG----------IHNWLVSNQNISFE 357 Query: 351 EMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLK 410 E+ +++ G+ + G VDI NG++ GA G+ +++G+I + ++ ISGN+ + Sbjct: 358 ELLKKMDQGILVTELMGQGVDIINGNYSRGA-VGFWVEKGKISYPINEITISGNLRNMWN 416 Query: 411 EIKAVGRDL 419 I ++ D+ Sbjct: 417 NIVSISSDV 425 >pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii >gi|3257260|dbj|BAA29943.1| (AP000003) 443aa long hypothetical protein [Pyrococcus horikoshii] Length = 443 Score = 89.3 bits (218), Expect = 8e-17 Identities = 64/212 (30%), Positives = 114/212 (53%), Gaps = 17/212 (8%) Query: 214 ARSP---PSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTV 270 AR+P P G +I DP LA + +G A A +V G S + + +K+ SE +T+ Sbjct: 212 ARNPEQGPEGRFDVIFDP-LAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEIVTI 270 Query: 271 IDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYA 330 D LP + + +DDEG+P K +I G+L YL + +K +GR ++ A Sbjct: 271 KDVGNLPNGYATRKFDDEGVPTKETILIHKGILKTYLFNTSLAKK-------YGR-ETTA 322 Query: 331 HVPLV--RMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV-DIANGSFMFGAKEG-YI 386 + L+ R N + PG++T +E+F+EVK G+Y+ + + G F ++G ++ Sbjct: 323 NAGLIAPRAWNIVLEPGDYTKDELFQEVKKGIYITNVWYTRFQNYMTGDFSTIPRDGIFL 382 Query: 387 IKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418 I+ GE+K +R++ +S N+L L+ + A+ ++ Sbjct: 383 IENGELK-PIRNIRVSDNMLRILQNVVALSKE 413 >pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (strain Orsay) >gi|5458676|emb|CAB50163.1| (AJ248287) hypothetical protein [Pyrococcus abyssi] Length = 443 Score = 87.8 bits (214), Expect = 2e-16 Identities = 63/212 (29%), Positives = 115/212 (53%), Gaps = 17/212 (8%) Query: 214 ARSP---PSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTV 270 AR+P P G+ +I DP LA + +G A A +V G S + + +K+ SE +T+ Sbjct: 212 ARNPEQGPEGKFDVIFDP-LAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEVVTI 270 Query: 271 IDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYA 330 D LP +G+ +DDEG+P + +I+ G L YL + +K +G+ ++ A Sbjct: 271 KDIGNLPNGYGTRKFDDEGVPTRETVLIERGTLKTYLFNTSLAKK-------YGK-ETTA 322 Query: 331 HVPLV--RMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV-DIANGSFMFGAKEG-YI 386 + L+ R N + PG++T +E+F+EVK G+Y+ + + G F ++G ++ Sbjct: 323 NAGLISPRAWNIVLEPGDYTKDELFQEVKRGIYITNVWYTRFQNYMTGDFSTIPRDGIFL 382 Query: 387 IKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418 I+ GE+K +R++ +S N+L L+ I + ++ Sbjct: 383 IENGELK-PIRNIRVSDNMLRILQNIVGLTKE 413 >pir||D81151 pmbA protein NMB0839 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226074|gb|AAF41250.1| (AE002437) pmbA protein [Neisseria meningitidis MC58] Length = 443 Score = 83.9 bits (204), Expect = 3e-15 Identities = 92/413 (22%), Positives = 179/413 (43%), Gaps = 41/413 (9%) Query: 23 FENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW-GFASTNDLSK--LEDTIKMAIKL 79 F ++ +V G++E +E ++ + + V + G AST D S+ L+DT+K AI + Sbjct: 33 FSESLGQSVSVRLGEIEQIEFQQDKSLDITVYVGKRKGRASTADFSEKALQDTVKAAIDI 92 Query: 80 AKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL----------EVEKMIRRD 129 A+ + + + + I + + DL+ + +GL E E++ + Sbjct: 93 ARHTAEDGCAGLADACLMAKHIGDPDLYHEWDLDTEAAVGLAKQCEQAALNEDERIENSE 152 Query: 130 --KIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT-YW-KSFGG 185 ++T + Y +Y N+ G S S VA + MQ YW S Sbjct: 153 GAAVQTGHYQY-------VYGNTHGFAAHRQGTHHSISCSVVAADENGMQRDYWYDSACR 205 Query: 186 TVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEA 245 + E++ + + L L +RS P+G P++ D ++G I +G A+ Sbjct: 206 HPDMDSPETI-----GQTAARRTLRRLGSRSIPTGSYPVLFDTTVSGGLIGHLVG-ALSG 259 Query: 246 DSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLN 305 ++ + S L IGKK+ + L + ++P +P F S +D EG+ +I++G++ Sbjct: 260 GALYRQSSFLIDSIGKKVLPDFLNLREEPHIPRSFRSSYFDAEGVATAPRFVIQNGIVEG 319 Query: 306 YLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGD 365 Y +++ L + G+ AH N Y+ T ++ +E+ G+ + Sbjct: 320 YFLSSYSARKLGMQTTGNAGG---AH-------NLYLNHTHETQSDLLKEMGTGLLVTEL 369 Query: 366 KGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418 G + G + GA G+ ++ G I V ++ ++G + D ++I V D Sbjct: 370 MGQGANTITGDYSRGA-AGFWVENGVIAYPVHEITVAGRLQDMYRDIVGVADD 421 >pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii >gi|3257987|dbj|BAA30670.1| (AP000006) 445aa long hypothetical protein [Pyrococcus horikoshii] Length = 445 Score = 83.5 bits (203), Expect = 5e-15 Identities = 52/199 (26%), Positives = 97/199 (48%), Gaps = 2/199 (1%) Query: 221 EMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKF 280 E P+I P H AL A + + + + L+ +G+KI S+ +T+ DD Sbjct: 222 EAPVIFSPWAISGLFHYALFPAFSGERLIKKTTPLADKVGEKIASDVITIYDDTFHELSV 281 Query: 281 GSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNT 340 + D EG+P ++ +I++GV ++ D +K GHG+ + +++ Sbjct: 282 VKAIADGEGVPTRKTMLIENGVFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVTIGLNSA 341 Query: 341 YIAPGEWTLEEMFEEVKFGVYMIGDKGG-QVDIANGSFMFGAKEGYIIKEGEIKEQVRDV 399 I G+ +LEEM +++K G + G +G + NG+F A Y+I++GEI + Sbjct: 342 VIENGKRSLEEMIQDIKHGYLVEGVQGAHSSNPDNGNFAISANPAYLIEDGEIAGSTVFL 401 Query: 400 GISGNILDTLKEIKAVGRD 418 ++ NI + LK+ V ++ Sbjct: 402 -VASNIYELLKQASEVSKE 419 >pir||H81869 hypothetical protein NMA1048 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379746|emb|CAB84314.1| (AL162755) hypothetical protein NMA1048 [Neisseria meningitidis Z2491] Length = 443 Score = 80.8 bits (196), Expect = 3e-14 Identities = 90/413 (21%), Positives = 177/413 (42%), Gaps = 41/413 (9%) Query: 23 FENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW-GFASTNDLSK--LEDTIKMAIKL 79 F ++ +V G++E +E ++ + + V + G A T D S+ L DT++ A + Sbjct: 33 FSESLGQSVSVRLGEIEQIEFQQDKSLDITVYVGKRKGRAGTADFSEQALRDTVRAAADI 92 Query: 80 AKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL----------EVEKMIRRD 129 A+ + + + +P I + + DL+ + +GL E E++ + Sbjct: 93 ARHTAEDGCAGLADPELMAQHIGDPDLYHEWDLDTEAAVGLAKQCEQAALNEDERIENSE 152 Query: 130 --KIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT-YW-KSFGG 185 ++T + Y +Y N+ G S S VA + MQ YW S Sbjct: 153 GAAVQTGHYQY-------VYGNTYGFAAHRQSTHHSISCSVVAADENGMQRDYWYDSACR 205 Query: 186 TVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEA 245 + E++ + + L L +RS P+G P++ D ++G I +G A+ Sbjct: 206 HPDMDSPETI-----GQTAARRTLRRLGSRSIPTGNYPVLFDTTVSGGLIGHLVG-ALSG 259 Query: 246 DSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLN 305 ++ + S L IGKK+ + L + ++P +P F S +D EG+ +I++G++ Sbjct: 260 GALYRQSSFLIDSIGKKVLPDFLNLREEPHIPRSFRSSYFDAEGVATAPRFVIQNGIVEG 319 Query: 306 YLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGD 365 Y +++ L + G+ AH N Y+ T ++ +E+ G+ + Sbjct: 320 YFLSSYSARKLGMQTTGNAGG---AH-------NLYLNHTHETQSDLLKEMGTGLLVTEL 369 Query: 366 KGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418 G + G + GA G+ ++ G I V ++ ++G + D ++I V D Sbjct: 370 MGQGANTITGDYSRGA-AGFWVENGVIAYPVHEITVAGRLQDMYRDIVGVADD 421 >pir||S75708 hypothetical protein sll0887 - Synechocystis sp. (strain PCC 6803) >gi|1001203|dbj|BAA10443.1| (D64003) hypothetical protein [Synechocystis sp.] Length = 446 Score = 80.4 bits (195), Expect = 4e-14 Identities = 95/411 (23%), Positives = 178/411 (43%), Gaps = 30/411 (7%) Query: 33 VENGKVEGVESNEEVGIGVRVLINGWGFASTNDLSKLEDTIKMAIKLAKVSNAEVPLY-- 90 V++G+ + VE++ + VRV W ++ D + I LA + AE + Sbjct: 37 VDSGEPKQVEASNRASVIVRV----WNEKGLVGVTSTTDLDQAGISLALETAAEASAFGI 92 Query: 91 VGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTSRF---------SYSDF 141 N + + + D+ E +G + +++ ++ + S+ Sbjct: 93 TDNIPDFSPEAQVPIGGAENDVAEPAPMGDLITTLVKAEQDLLASHPAITGVPYNGLSEQ 152 Query: 142 VTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVESVDFNYWA 201 T + YLNS G+ + R Y S+ +R+ + + + +L S+D + Sbjct: 153 TTERFYLNSAGA--KRYECRSYASIYLYSRAEQEGKKPRSAGEMKISRDLA-SLDIDGCL 209 Query: 202 NFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSG-MIG 260 + K LS L R P+G+ ++ A + + A + A S+ +S+ + +G Sbjct: 210 QTVKEKTLSHLDYRPIPTGKYTVVFSAR-AFLSLLGAFSNLYNAQSILDKQSLATKETLG 268 Query: 261 KKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVP 320 I SE L V DD PG + +D EG P +RV+IIK+GVL L+ T+K + P Sbjct: 269 TAIASELLCVSDDALHPGNISAERFDGEGTPTRRVDIIKNGVLTGLLHSAGTAKRFDTQP 328 Query: 321 NGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMF--EEVKFGVYM--IGDKGGQVDIANGS 376 GH S V ++ Y E T E+ + ++ + VY+ + V+ GS Sbjct: 329 TGHANIGSKITVG----AHFYHVYSEKTAEKSYSLDQAENVVYIDKLQALHAGVNSLQGS 384 Query: 377 FMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFC 427 F +G+++ +GE K+ + ++G+ L+ LK I + + ++ G C Sbjct: 385 FSL-PFDGWLVNKGE-KQSIDAATVAGDFLEVLKTIVYLEPEAEVTPGGVC 433 >dbj|BAB05756.1| (AP001514) unknown conserved protein in others [Bacillus halodurans] Length = 419 Score = 79.6 bits (193), Expect = 7e-14 Identities = 53/182 (29%), Positives = 90/182 (49%), Gaps = 3/182 (1%) Query: 237 EALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVE 296 +ALG+ AD++ + L M GK+I S T+ D LP S +DDEG+ + + Sbjct: 216 KALGNLFIADTIDRSVPALWKMKGKRIASTVFTLKDQAHLPQSIASSPFDDEGVLSQDIT 275 Query: 297 IIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEV 356 I+ G + L+ ++ + + NG +S+ P ++ +N + PG + E + +E+ Sbjct: 276 ILAKGTFQHALHSITSASKHHQISNGRAYRKSFDLAPKIQYTNLLVEPGTRSTENLLKEM 335 Query: 357 KFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVG 416 K G + GQ I G MF A +G+ I EG+ E++ V I + L+ I AV Sbjct: 336 KTGFLINRSFDGQ--IIAGRLMFKA-DGWKIHEGQRVERISRVRIEAPLFQMLRSIVAVA 392 Query: 417 RD 418 +D Sbjct: 393 KD 394 >pir||B75180 antibiotic/peptide maturation related protein PAB1956 - Pyrococcus abyssi (strain Orsay) >gi|5458031|emb|CAB49521.1| (AJ248284) ANTIBIOTIC/PEPTIDE MATURATION related protein [Pyrococcus abyssi] Length = 448 Score = 76.9 bits (186), Expect = 4e-13 Identities = 92/426 (21%), Positives = 175/426 (40%), Gaps = 19/426 (4%) Query: 2 IDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVE-GVESNEEVGI--GVRVLINGW 58 ++EL EK+ +E++ + R E VE ++ G E+V I G++ G Sbjct: 7 MEELIKYGEKFFDELEIVVRRSRGI---EVNVELNEISMGATRIEKVTIIRGIKDKRVGI 63 Query: 59 GFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQK--KDFLDVDLEEKT 116 T+ +++ I+ A K+AK++ + + P GK K K +D V E Sbjct: 64 AIIDTDSKEEVKKAIEEAAKMAKLNTPDEK-WSSLPSPGKYREKPKVSEDLKSVSTETLV 122 Query: 117 KLGLEVEKMIRRD--KIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSAD 174 + K+ R + + S NS+G + + V + Sbjct: 123 EFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEG 182 Query: 175 IMQTYWKSFGGTVGWEL-VESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGV 233 ++ F EL VE V N + + + + E +I P Sbjct: 183 VVTPGIFDFDAKDNLELDVEGV-----VNRGLERVKWAYNVKEAKNEETTVIFGPWAISG 237 Query: 234 FIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGK 293 + AL A + + + + L+ +G+K+ S+ +T+ DD + D EG+P + Sbjct: 238 LLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTR 297 Query: 294 RVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMF 353 +V +I++G+ ++ D +K GHG+ + +++ I G+ L E+ Sbjct: 298 KVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEII 357 Query: 354 EEVKFGVYMIGDKGG-QVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEI 412 E+K G + G +G + NG+F A Y+I++GE+ + I+GN+ + LK+ Sbjct: 358 GEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFL-IAGNVYELLKQA 416 Query: 413 KAVGRD 418 V +D Sbjct: 417 TEVSKD 422 >pir||I64173 hypothetical protein HI1653 - Haemophilus influenzae (strain Rd KW20) Length = 122 Score = 76.5 bits (185), Expect = 6e-13 Identities = 43/118 (36%), Positives = 70/118 (58%), Gaps = 3/118 (2%) Query: 336 RMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQ 395 RM+NTY+ G+ +++ VK G+Y GGQVDI +G F+F E Y+I++G+I + Sbjct: 3 RMTNTYMLAGQSQFDDLIASVKQGIYAPHFGGGQVDITSGKFVFSTSEAYLIEKGKITKP 62 Query: 396 VRDVGISGNILDTLKEIKAVGRDLKIEFP-GFCGK-GQWVPVDDGGPHVLVKAI-VGG 450 V+ + G+ ++ +++I V +++ G CGK GQ VPV G P + + I VGG Sbjct: 63 VKGATLIGSGIEVMQKISMVADKSELDLGIGVCGKEGQSVPVGVGQPALKIDEITVGG 120 >sp|Q57684|Y231_METJA HYPOTHETICAL PROTEIN MJ0231 >gi|2128001|pir||H64328 hypothetical protein MJ0231 - Methanococcus jannaschii >gi|1590966|gb|AAB98219.1| (U67479) pmbA protein (pmbA) [Methanococcus jannaschii] Length = 416 Score = 75.7 bits (183), Expect = 1e-12 Identities = 103/414 (24%), Positives = 179/414 (42%), Gaps = 31/414 (7%) Query: 4 ELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW-GFAS 62 +L LI+ E ++ F + ++ V+ ++ GIGVRV+ +G GFA Sbjct: 2 DLEKLIKIGEKEGFETEVLFVKSYEVSVDLDGKSVDSFQTGISYGIGVRVIKDGKVGFAY 61 Query: 63 TNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEV 122 N E+ + A+K + E K + K+ LD+D EEK LE Sbjct: 62 ANKFD--ENIVYKAMKNLVEDKYTEFAHPQKYKEPKGMFY--KEILDLD-EEKL---LED 113 Query: 123 EKMIRRDKIKTSRFSYSDFVTRKI----YLNSEGSVIETVVPRIYFSLSAVARSADIMQT 178 +R + + S V++++ +NS G +E YFS + IM Sbjct: 114 LITMRDIALDNNAIVLSGGVSKEVGYARLINSNGVDVEE--QDTYFSAAI-----SIMYD 166 Query: 179 YWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEA 238 S+ + + + +Y A ++ K+ + + S + I++ P + Sbjct: 167 GETSYECRTRHNIFDVEEISYRALDLAKKSANGKAI----SYKGNIVLSPRALYDLLSYT 222 Query: 239 LGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298 L A A++V++ S+L G IG++I E +T+IDD TL S D EG ++ ++ Sbjct: 223 LMPAFSAENVQRDRSVLKGKIGEQIFGENITIIDDGTLDYALYSSKCDGEGTATQKTVLV 282 Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358 ++GVL NYL D + + G+ ++ Y +P V +N I + +L++ F+E Sbjct: 283 ENGVLKNYLYDIKRANREGKTSTGNA-SRGYRSLPYVSPTNFIIKETKNSLDD-FDEY-- 338 Query: 359 GVYMIGDKGGQV-DIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKE 411 VY+ G G + G F + Y K G+I R + GNI + KE Sbjct: 339 -VYINGVIGSHTSNPITGDFAVEIQNSYYYKNGKIIPIKRGM-FGGNIFEMFKE 390 >emb|CAC11943.1| (AL445065) conserved hypothetical protein [Thermoplasma acidophilum] Length = 430 Score = 74.9 bits (181), Expect = 2e-12 Identities = 58/201 (28%), Positives = 96/201 (46%), Gaps = 9/201 (4%) Query: 220 GEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGK 279 G +I+ P AG I +A A +V G S L +G++I + + + DDPT Sbjct: 208 GHYDVILAPMAAGNIITSG-SYAFSAHTVISGLSFLQDSMGRQIAAPMVNLYDDPTDTAG 266 Query: 280 FGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSN 339 V+D+EG RV II+ GVL YL+ T++ +N G+ A + Sbjct: 267 MAYRVFDEEGTATSRVPIIEHGVLNTYLHSTSTARYMNTETTGN------AGIISPEAWQ 320 Query: 340 TYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV-DIANGSFMFGAKEG-YIIKEGEIKEQVR 397 + G+ + EE+ + + GV++ + D NG F ++G Y I+ GEI E Sbjct: 321 LEMDGGDASAEELISDTREGVFIRNSWYLRFQDYRNGVFSTVPRDGVYYIRNGEIAEAWD 380 Query: 398 DVGISGNILDTLKEIKAVGRD 418 + IS +I + LK+I A+ ++ Sbjct: 381 GIRISDSIPEILKKISALSKE 401 >gi|11498264 antibiotic maturation protein (pmbA) [Archaeoglobus fulgidus] >gi|7429843|pir||H69331 hypothetical protein AF0656 - Archaeoglobus fulgidus >gi|2649962|gb|AAB90584.1| (AE001059) antibiotic maturation protein (pmbA) [Archaeoglobus fulgidus] Length = 391 Score = 74.5 bits (180), Expect = 2e-12 Identities = 93/394 (23%), Positives = 166/394 (41%), Gaps = 57/394 (14%) Query: 33 VENGKVEGVESNEEVGIGVRVLINGW-GFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYV 91 +E G+++ V S + RV++ G GFAS S ++ + +A K+A++S E+ + Sbjct: 17 IEAGRLKIVSSYVDKSFSARVILKGRVGFASA---STRDEALSLAEKIARISEDELEDFP 73 Query: 92 GN-PVEGKAIIKQKKDFLDVDL--EEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTRKIYL 148 P K I ++ + D +L EE +L VEK Sbjct: 74 NEKPASVKGIYDKRVEEADSELIMEEFERLRSAVEKA----------------------- 110 Query: 149 NSEGSVIETVVPRIY----FSLSAVARSADIMQTYWKSFGGTVGWELVES----VDFNYW 200 N + IE V + F L + +S F G +E+ S +D Sbjct: 111 NIASATIEHAVEEVRITNSFGLDSREKSTSSSMIVEAVFEGGSAYEVCGSRSIELDIEGA 170 Query: 201 ANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIG 260 A A+ A G +I+ P + L ++ A++V +G S++ +G Sbjct: 171 AKKAEELAVDSAKAIKIEGGTYDVILQPIAVHQLLSNTLYPSLSAENVEKGRSVIR--LG 228 Query: 261 KKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVP 320 + G +TVIDDPT+ G S +DDEG+ ++ +I +GV+ +Y D + SK + Sbjct: 229 DEFG--RITVIDDPTVEGGLMSCGFDDEGVSARKTFLIDNGVVRSYYTDWKHSKKYGVTG 286 Query: 321 NGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVY-MIGDKGGQVDIANGSFMF 379 NG +S P+V SN + +++ ++ ++ +IG + +G F Sbjct: 287 NGFRLEESSFPAPMV--SNVVL-----EVDDADDDNCLTIHSLIGSH--TANPVSGDFSL 337 Query: 380 GAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIK 413 Y GE + V+ I GN+ + LK+++ Sbjct: 338 ECNNAYF---GE--KAVKGAMIYGNVFELLKKVE 366 >gb|AAF65318.1|AF234655_1 (AF234655) LmbIH [Streptomyces lincolnensis] Length = 199 Score = 69.5 bits (167), Expect = 8e-11 Identities = 49/170 (28%), Positives = 78/170 (45%), Gaps = 3/170 (1%) Query: 264 GSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGH 323 GSE ++V+ DPT G G+ +DDEG P +I+ G L+ L+ R + A Sbjct: 1 GSEHVSVVADPTGTGA-GATPWDDEGTPTAAAPLIERGTLVGLLSSRTVAAASGRPLTAA 59 Query: 324 GRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKE 383 G A +PLVRM+N + PG T +++ + + G+ + G+ +D F F + Sbjct: 60 GARAEGAALPLVRMTNVNLLPGSGTEQDLLDTMGEGLLLTGNHSFSIDDHREVFHFTCEL 119 Query: 384 GYIIKEGEIKEQVRDVGISGNILDTLKEIKAVG--RDLKIEFPGFCGKGQ 431 + I+ G+ E +R G LD + V + FC KGQ Sbjct: 120 AWRIRGGQRVEPLRGPRYHGRTLDFWRSCAHVAGPEAWTMHSVTFCMKGQ 169 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.316 0.138 0.395 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 171487902 Number of Sequences: 2977 Number of extensions: 7576424 Number of successful extensions: 18092 Number of sequences better than 1.0e-10: 58 Number of HSP's better than 0.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 17930 Number of HSP's gapped (non-prelim): 60 length of query: 452 length of database: 189,106,746 effective HSP length: 57 effective length of query: 395 effective length of database: 154,992,987 effective search space: 61222229865 effective search space used: 61222229865 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 166 (69.1 bits)