BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0154 (tldD) DE:TLDD PROTEIN
         (452 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Ors...   908  0.0
pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii >gi|3256...   689  0.0
sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir...   350  2e-95
sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|...   321  1e-86
pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii            321  1e-86
pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (st...   290  2e-77
gi|11498263 conserved hypothetical protein [Archaeoglobus fulgid...   290  2e-77
pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii ...   281  1e-74
pir||G75033 hypothetical protein PAB1547 - Pyrococcus abyssi (st...   260  3e-68
pir||D71135 tldD-related protein PH0848 - Pyrococcus horikoshii ...   254  2e-66
pir||D72762 hypothetical protein APE0089 - Aeropyrum pernix (str...   252  6e-66
gb|AAK40965.1| Zn-dependent protease, tldD protein homolog, puta...   238  1e-61
emb|CAB57642.1| (Y18930) hypothetical protein [Sulfolobus solfat...   238  1e-61
sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD p...   231  1e-59
pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (gr...   223  3e-57
sp|P73754|Y863_SYNY3 HYPOTHETICAL 50.4 KD PROTEIN SLR0863 >gi|74...   220  2e-56
gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum]               219  5e-56
pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07...   217  2e-55
pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa ...   215  8e-55
sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13...   215  8e-55
pir||D72342 tldD protein - Thermotoga maritima (strain MSB8) >gi...   209  5e-53
pir||D83086 conserved hypothetical protein PA4474 [imported] - P...   205  9e-52
sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG                             199  7e-50
pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria ...   191  1e-47
pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningit...   191  1e-47
emb|CAC11942.1| (AL445065) conserved hypothetical protein [Therm...   185  9e-46
gb|AAK41402.1| Conserved hypothetical protein [Sulfolobus solfat...   182  6e-45
pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment)        173  5e-42
dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity...   158  1e-37
sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|74...   153  4e-36
pir||E70461 pmbA protein - Aquifex aeolicus >gi|2984159|gb|AAC07...   144  2e-33
pir||B83330 hypothetical protein PA2529 [imported] - Pseudomonas...   136  4e-31
pir||E72342 pmbA-related protein - Thermotoga maritima (strain M...   133  4e-30
pir||D70703 tldD homolog Rv2315c - Mycobacterium tuberculosis (s...   125  7e-28
pir||T36780 hypothetical protein SCI28.10 - Streptomyces coelico...   116  6e-25
gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis]         113  4e-24
pir||B71249 hypothetical protein PH0249 - Pyrococcus horikoshii ...   111  1e-23
pir||B69009 conserved hypothetical protein MTH1070 - Methanobact...   110  3e-23
sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||...   102  6e-21
pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus aby...   100  3e-20
pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (st...    99  9e-20
pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (gr...    97  5e-19
sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C6418...    96  6e-19
pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aerugin...    94  3e-18
sp|P57191|PMBA_BUCAI PMBA PROTEIN HOMOLOG >gi|10038774|dbj|BAB12...    93  7e-18
pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii ...    89  8e-17
pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (st...    88  2e-16
pir||D81151 pmbA protein NMB0839 [imported] - Neisseria meningit...    84  3e-15
pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii ...    83  5e-15
pir||H81869 hypothetical protein NMA1048 [imported] - Neisseria ...    81  3e-14
pir||S75708 hypothetical protein sll0887 - Synechocystis sp. (st...    80  4e-14
dbj|BAB05756.1| (AP001514) unknown conserved protein in others [...    80  7e-14
pir||B75180 antibiotic/peptide maturation related protein PAB195...    77  4e-13
pir||I64173 hypothetical protein HI1653 - Haemophilus influenzae...    76  6e-13
sp|Q57684|Y231_METJA HYPOTHETICAL PROTEIN MJ0231 >gi|2128001|pir...    76  1e-12
emb|CAC11943.1| (AL445065) conserved hypothetical protein [Therm...    75  2e-12
gi|11498264 antibiotic maturation protein (pmbA) [Archaeoglobus ...    75  2e-12
gb|AAF65318.1|AF234655_1 (AF234655) LmbIH [Streptomyces lincolne...    69  8e-11

>pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Orsay)
           >gi|5457661|emb|CAB49152.1| (AJ248283) TLDD PROTEIN
           [Pyrococcus abyssi]
           Length = 452
           
 Score =  908 bits (2320), Expect = 0.0
 Identities = 452/452 (100%), Positives = 452/452 (100%)

Query: 1   MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWGF 60
           MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWGF
Sbjct: 1   MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWGF 60

Query: 61  ASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL 120
           ASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL
Sbjct: 61  ASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL 120

Query: 121 EVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW 180
           EVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW
Sbjct: 121 EVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW 180

Query: 181 KSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG 240
           KSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG
Sbjct: 181 KSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG 240

Query: 241 HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD 300
           HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD
Sbjct: 241 HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD 300

Query: 301 GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV 360
           GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV
Sbjct: 301 GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV 360

Query: 361 YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420
           YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK
Sbjct: 361 YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420

Query: 421 IEFPGFCGKGQWVPVDDGGPHVLVKAIVGGRE 452
           IEFPGFCGKGQWVPVDDGGPHVLVKAIVGGRE
Sbjct: 421 IEFPGFCGKGQWVPVDDGGPHVLVKAIVGGRE 452


>pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii
           >gi|3256635|dbj|BAA29318.1| (AP000001) 504aa long
           hypothetical tldd protein [Pyrococcus horikoshii]
           Length = 504
           
 Score =  689 bits (1759), Expect = 0.0
 Identities = 321/454 (70%), Positives = 387/454 (84%), Gaps = 2/454 (0%)

Query: 1   MIDELRNLIEKYSN--EVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW 58
           MIDE+  ++EKYS+  E+KFMDIR E+  YTE T+ENGKVE +E+N E G+GVRVLINGW
Sbjct: 51  MIDEILKVLEKYSSSSEIKFMDIRMESIEYTELTIENGKVENLENNGERGVGVRVLINGW 110

Query: 59  GFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKL 118
           GFASTNDL+K+E+ +K AIK+AKVS     +Y  +P+E    +KQ     D+DLEEK KL
Sbjct: 111 GFASTNDLTKIEEIVKTAIKMAKVSRISTSVYTRDPIEDNVEVKQGIKLKDIDLEEKVKL 170

Query: 119 GLEVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT 178
           G+EV  M++R+ IKT +FSYSD + +K+YL+SEGS+IE+ VPR+Y S+S+VA+ +  MQT
Sbjct: 171 GVEVNNMLKRENIKTRKFSYSDIIVKKLYLSSEGSIIESTVPRVYLSISSVAKFSGKMQT 230

Query: 179 YWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEA 238
           YWKSFGGT GWE+VE +DF +WANF+S KA+SLLSARSPPSGEM +IMDPELAGVFIHEA
Sbjct: 231 YWKSFGGTGGWEIVEKIDFEHWANFVSKKAVSLLSARSPPSGEMQVIMDPELAGVFIHEA 290

Query: 239 LGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298
           LGHA EAD+V+Q ESIL+GM+GK+I  EELTV+DDPTLPGKFGSY+YDDEG+PGKRVEII
Sbjct: 291 LGHASEADAVKQEESILAGMLGKRIAVEELTVVDDPTLPGKFGSYIYDDEGIPGKRVEII 350

Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358
           +DGVL+NYLNDRETS  LNL PNGHGRAQSY+HVPLVRMSNTYI PG+W  EE+ +EVKF
Sbjct: 351 RDGVLVNYLNDRETSSLLNLEPNGHGRAQSYSHVPLVRMSNTYIEPGDWRFEEILDEVKF 410

Query: 359 GVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418
           GVYMIGDKGGQVD+A+G+FMF AKEGY+++ GEIK  +RDV +SGNIL  L+EIKA+G D
Sbjct: 411 GVYMIGDKGGQVDVASGNFMFAAKEGYLVENGEIKGHLRDVALSGNILSALREIKAIGND 470

Query: 419 LKIEFPGFCGKGQWVPVDDGGPHVLVKAIVGGRE 452
           LKIEFPGFCGKGQWVPVDDGGPHVL KAIVGG E
Sbjct: 471 LKIEFPGFCGKGQWVPVDDGGPHVLTKAIVGGLE 504


>sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir||C69214 zinc
           metalloproteinase - Methanobacterium thermoautotrophicum
           (strain Delta H) >gi|2621948|gb|AAB85354.1| (AE000862)
           zinc metalloproteinase [Methanobacterium
           thermoautotrophicum]
           Length = 454
           
 Score =  350 bits (889), Expect = 2e-95
 Identities = 193/451 (42%), Positives = 277/451 (60%), Gaps = 6/451 (1%)

Query: 3   DELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFA 61
           D L +++    + V++ DIR   +  +   +++GK++ V+S    G  +RVL NG WGFA
Sbjct: 6   DYLGSILMDIEDRVEYADIRAGTSRTSSILMKDGKLQEVKSGRASGFRIRVLRNGSWGFA 65

Query: 62  STNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLE 121
            T++ S+L +    AIK+      +V +  G P   K +++  +   DV   EK +L  +
Sbjct: 66  FTDEPSRLGEMALKAIKMTGSLRGDVQVGSGAPSVDKTMVRSSRPPSDVPAAEKRELVSD 125

Query: 122 VEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWK 181
                  D + ++  SY D  +   +LNSEGS+IE    R+   L+AVA     +Q   K
Sbjct: 126 AHHAASVDGVVSTTVSYVDMESSSAFLNSEGSLIEMAETRVALFLNAVASDGSGIQFGHK 185

Query: 182 SFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGH 241
           S GGT G+E++E  D          KA+ LL A  PPSG   I+ DPEL GVFIHEALGH
Sbjct: 186 SCGGTGGFEILEREDIEELGRRTGEKAVRLLKASPPPSGRFDIVTDPELTGVFIHEALGH 245

Query: 242 AVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDG 301
           A EAD + QG+SIL G +G+KI SE +T+IDDPT+ G FGSY YD EG+      ++++G
Sbjct: 246 AAEADLILQGDSILEGKLGEKIASEGVTIIDDPTIDG-FGSYSYDAEGVRAAETVLVENG 304

Query: 302 VLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVY 361
           VL + LN RET+  L L P+G+ R+ +    P+VRMSNTY+ PG+ + +E+ E+++ GVY
Sbjct: 305 VLTSLLNSRETAFKLGLEPSGNARS-AIGDQPIVRMSNTYLKPGDLSFDELIEDIRNGVY 363

Query: 362 MIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKI 421
           + G +GGQVD   G F F A E + I++GEI E V+DV +SGN+L+TLK +  VG D ++
Sbjct: 364 LRGSRGGQVDTGKGIFQFNAAESFRIQDGEIAEPVKDVSLSGNVLETLKNVDGVGSDFRL 423

Query: 422 EFPGFCGK-GQWVPVDDGGPHVLVK-AIVGG 450
              GFCGK GQ VPV DGGPHV ++ A+VGG
Sbjct: 424 GI-GFCGKSGQSVPVGDGGPHVRIRNAMVGG 453


>sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|AAB99001.1| (U67542)
           conserved hypothetical protein [Methanococcus
           jannaschii]
           Length = 451
           
 Score =  321 bits (814), Expect = 1e-86
 Identities = 189/451 (41%), Positives = 277/451 (60%), Gaps = 18/451 (3%)

Query: 9   IEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLI-NGWGFASTNDLS 67
           IEK      + DIR         T+++GK+E + S    G+ VRVL  NGWGF ++N +S
Sbjct: 7   IEKLLEVGDYADIRINFGESNTITLKDGKIEEISSGFGNGVAVRVLYKNGWGFVTSNIVS 66

Query: 68  K--LEDTIKMAIKLAKVSN--AEVPLYVGNPVEGKAIIKQKKDF-----LDVDLEEKTKL 118
           +  +E  I  A K+AK+SN  +E  + +    + KAII   K        DVD+EEK ++
Sbjct: 67  EEEIEKLINKAYKMAKISNEYSEKEIILK---DYKAIIDNYKMIGKINPTDVDIEEKKEI 123

Query: 119 GLEVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT 178
            ++  K +  +KIK+   SYSD   ++I++ SEGS IE  + R    ++ VA+    +Q 
Sbjct: 124 IIDTYKNMTDEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNCVAKENGNLQ- 182

Query: 179 YWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEA 238
           Y     G  G+E ++    N  A    ++AL LL A+  P G+  +I+DPELAGVFIHEA
Sbjct: 183 YGAERTGGFGFEKIKDNYLNL-ALEAKNRALRLLKAKPCPKGKFKVILDPELAGVFIHEA 241

Query: 239 LGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298
           +GHA EAD V Q +S+    +G+++GSE +TVIDD T+ G FGSY YDDEG+ GK+  II
Sbjct: 242 VGHASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYKYDDEGVEGKKTVII 301

Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358
           ++G+L  YL+ RET+  ++    G+GRA+   + P+VRMSNT+I PG+W+ EE+ E+ K 
Sbjct: 302 ENGILKTYLHSRETAGRMDAELTGNGRAEG-LNKPIVRMSNTFIKPGDWSFEELLEDTKE 360

Query: 359 GVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418
           G+++ G +GGQVD   G F F A E Y+I+ GE+ + ++D G+SG ILD L ++ AV +D
Sbjct: 361 GIFLKGSRGGQVDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGEILDILFKVDAVTKD 420

Query: 419 LKIEFPGFCGK-GQWVPVDDGGPHVLVKAIV 448
            ++   G+CGK GQ VPV DGG  V   A V
Sbjct: 421 FELSV-GYCGKDGQSVPVGDGGGCVRTIATV 450


>pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii
           Length = 451
           
 Score =  321 bits (813), Expect = 1e-86
 Identities = 189/449 (42%), Positives = 274/449 (60%), Gaps = 14/449 (3%)

Query: 9   IEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLI-NGWGFASTNDLS 67
           IEK      + DIR         T+++GK+E + S    G+ VRVL  NGWGF ++N +S
Sbjct: 7   IEKLLEVGDYADIRINFGESNTITLKDGKIEEISSGFGNGVAVRVLYKNGWGFVTSNIVS 66

Query: 68  K--LEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDF-----LDVDLEEKTKLGL 120
           +  +E  I  A K+AK+SN E         + KAII   K        DVD+EEK ++ +
Sbjct: 67  EEEIEKLINKAYKMAKISN-EYSEKEXILKDYKAIIDNYKMIGKINPTDVDIEEKKEIII 125

Query: 121 EVEKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW 180
           +  K +  +KIK+   SYSD   ++I++ SEGS IE  + R    ++ VA+    +Q Y 
Sbjct: 126 DTYKNMTDEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNCVAKENGNLQ-YG 184

Query: 181 KSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG 240
               G  G+E ++    N  A    ++AL LL A+  P G+  +I+DPELAGVFIHEA+G
Sbjct: 185 AERTGGFGFEKIKDNYLNL-ALEAKNRALRLLKAKPCPKGKFKVILDPELAGVFIHEAVG 243

Query: 241 HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD 300
           HA EAD V Q +S+    +G+++GSE +TVIDD T+ G FGSY YDDEG+ GK+  II++
Sbjct: 244 HASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYKYDDEGVEGKKTVIIEN 303

Query: 301 GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV 360
           G+L  YL+ RET+  ++    G+GRA+   + P+VRMSNT+I PG+W+ EE+ E+ K G+
Sbjct: 304 GILKTYLHSRETAGRMDAELTGNGRAEG-LNKPIVRMSNTFIKPGDWSFEELLEDTKEGI 362

Query: 361 YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420
           ++ G +GGQVD   G F F A E Y+I+ GE+ + ++D G+SG ILD L ++ AV +D +
Sbjct: 363 FLKGSRGGQVDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGEILDILFKVDAVTKDFE 422

Query: 421 IEFPGFCGK-GQWVPVDDGGPHVLVKAIV 448
           +   G+CGK GQ VPV DGG  V   A V
Sbjct: 423 LSV-GYCGKDGQSVPVGDGGGCVRTIATV 450


>pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (strain Orsay)
           >gi|5458032|emb|CAB49522.1| (AJ248284) TLDD RELATED
           PROTEIN [Pyrococcus abyssi]
           Length = 458
           
 Score =  290 bits (735), Expect = 2e-77
 Identities = 167/436 (38%), Positives = 253/436 (57%), Gaps = 13/436 (2%)

Query: 15  EVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTI 73
           + +++++R+E+   T  T+++G           G+ +RVL NG WGF+ST+DLSKLE+ I
Sbjct: 19  KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAI 78

Query: 74  KMAIKLAKVSNA----EVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRD 129
           K A KLAK ++     ++ L    PVE     K K    +VD+EEK K   E+EK+++ D
Sbjct: 79  KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKED 138

Query: 130 K-IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGT-V 187
           + +K+    Y D   +KI L +EG+ IE     ++ S+    +    +     S G    
Sbjct: 139 ETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDY 198

Query: 188 GWELVESVDFNYWA-NFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246
           GWEL+   + N    + +  K  S L+  +P  GE P++  P + G+  HEALGH  EAD
Sbjct: 199 GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEAD 258

Query: 247 SVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNY 306
                 S    ++GK+I  E +T+  +  + G FG+  YDDEG+P K + II++G+L   
Sbjct: 259 LTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEI 315

Query: 307 LNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDK 366
           + +RE +   N+ PNGH RAQ Y + P++RM NT   PG+W+ EEM E++KFG Y++  +
Sbjct: 316 MLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFR 375

Query: 367 GGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGF 426
           GGQ  + N +F  G +EGY+I+ GEI E +RD  I+G  ++ LK+I AVG+D  IE  GF
Sbjct: 376 GGQAQL-NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIE-TGF 433

Query: 427 CGKGQWVPVDDGGPHV 442
           CGKGQ   V  GGPH+
Sbjct: 434 CGKGQIAFVSSGGPHM 449


>gi|11498263 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|3123065|sp|O29602|Y655_ARCFU HYPOTHETICAL PROTEIN
           AF0655 >gi|7429834|pir||G69331 conserved hypothetical
           protein AF0655 - Archaeoglobus fulgidus
           >gi|2649963|gb|AAB90585.1| (AE001059) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 425
           
 Score =  290 bits (735), Expect = 2e-77
 Identities = 180/441 (40%), Positives = 264/441 (59%), Gaps = 23/441 (5%)

Query: 16  VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTN--DLSKLEDT 72
           ++F DIR    +     +ENGK+E    N+    G RVL NG WG    N  D   L   
Sbjct: 1   MRFWDIRRVENVSLNLQLENGKLEKPRYNKSTSKGFRVLKNGFWGIFEGNVADDEGLRQA 60

Query: 73  IKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIK 132
            K A         E+        +G+  ++ K+D  D+ +EEK +L  ++EK+IR D   
Sbjct: 61  EKNAFTQGDGDIEEIA------TKGRYRMRVKRDPQDMSIEEKVELLKDLEKIIR-DVCV 113

Query: 133 TSRFSYSDFVTRKI--YLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWE 190
           +++  Y  F  R++  Y +S GS +E  V R   S+  V +   + Q   K      G+E
Sbjct: 114 STKLVY--FENRRVLQYRDSCGSEVEYEVLRTGVSIMGVGKGRSL-QFLSKRQMRVGGYE 170

Query: 191 LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQ 250
           +++ VD   +   I      L++A +PPSGEM ++MD  LAGVF+HEA GHAVEAD V Q
Sbjct: 171 VLDGVDEKAYE--IVEVLPKLVNALAPPSGEMSVVMDSSLAGVFVHEAFGHAVEADHVLQ 228

Query: 251 GESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDR 310
           G ++L G + +K+  E +T+IDDPTLP +FG + +DDEG+  ++  I++DGVL ++L+ R
Sbjct: 229 GATVLKGRLNEKVADESVTIIDDPTLP-EFGFFPFDDEGVRAEKKVIVEDGVLKSFLHSR 287

Query: 311 ETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV 370
           ET+K L  V  G+ R+Q    VP+VRMSNTYI    ++ +E+ EE + GVY++G +GG+ 
Sbjct: 288 ETAKKLGGVA-GNARSQG-VDVPIVRMSNTYIDTHHYSFDELLEECRDGVYLVGSRGGET 345

Query: 371 DIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFCGK- 429
           + A G F F A+ GY+IK GE+ E VRDV +SGN L+ L+ +K +GR+++ + PGFCGK 
Sbjct: 346 NPATGYFHFNAQYGYLIKNGELAEMVRDVSLSGNTLEILRNVK-IGREIEFD-PGFCGKA 403

Query: 430 GQWVPVDDGGPHVLVKAIVGG 450
           GQ VPV DG P VL +A VGG
Sbjct: 404 GQLVPVSDGSPPVLCRATVGG 424


>pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii
           >gi|3257986|dbj|BAA30669.1| (AP000006) 458aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 458
           
 Score =  281 bits (711), Expect = 1e-74
 Identities = 161/436 (36%), Positives = 249/436 (56%), Gaps = 13/436 (2%)

Query: 15  EVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTI 73
           + +++++R+E+   T   +++G           G+ +RVL+NG WGF+ST++L K+E+ I
Sbjct: 19  KAEYIELRYEDIKRTALNLKDGVFVNFTEKLNRGVAIRVLVNGAWGFSSTSELDKVEEAI 78

Query: 74  KMAIKLAKVSNA----EVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRD 129
           K A KLAKV++     ++ L    PVE     K K    +VD+EEK     E+E +++ D
Sbjct: 79  KEAYKLAKVASETKKEKIKLAEIKPVEDFVKSKMKIKPREVDIEEKINHLKELENLLKED 138

Query: 130 K-IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGT-V 187
           K +K+    Y D   +KI L +EG+ IE     ++  +    +    +     + G    
Sbjct: 139 KAVKSVNIRYEDGGGQKILLTNEGTKIEWDYNYLWQGVYVTGKEDGKLAMARDTIGAVDY 198

Query: 188 GWELVESVDFNYWA-NFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246
           GWEL+   + N    + I  K  S L   +P  GE P++  P + G+  HEALGH  EAD
Sbjct: 199 GWELMTEKEPNEKVRDRILRKLHSQLKGITPKRGEFPVVAGPIIVGIIAHEALGHLAEAD 258

Query: 247 SVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNY 306
                 S    ++GK+I  E +T+  +  + G FG+  YDDEG+P + + II++G+L   
Sbjct: 259 LTMN--SPFKDLLGKQIAPEYVTM-SERHVEGGFGNDKYDDEGVPVRDIHIIENGILKEI 315

Query: 307 LNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDK 366
           + +RE +   N+ PNGH RAQ Y + P++RM NT   PG+W+ EEM E++KFG Y++  +
Sbjct: 316 MLNREYATKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFR 375

Query: 367 GGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGF 426
           GGQ  + N +F  G +EGY+I+ GEI E +RD  I+G  ++ LK+I AVG+D  IE  GF
Sbjct: 376 GGQAQL-NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKITAVGKDFGIEV-GF 433

Query: 427 CGKGQWVPVDDGGPHV 442
           CGKGQ   V  GGPH+
Sbjct: 434 CGKGQTAFVSSGGPHM 449


>pir||G75033 hypothetical protein PAB1547 - Pyrococcus abyssi (strain Orsay)
           >gi|5458677|emb|CAB50164.1| (AJ248287) hypothetical
           protein [Pyrococcus abyssi]
           Length = 473
           
 Score =  260 bits (657), Expect = 3e-68
 Identities = 154/451 (34%), Positives = 258/451 (57%), Gaps = 22/451 (4%)

Query: 18  FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSK--LEDTIK 74
           + + RFE    T  +++NG  +G++   + GIG+RVL++G  GFASTN L+K  + +T++
Sbjct: 19  YAEARFEEKQGTSLSMKNGVPQGMQLLSDRGIGIRVLVDGGMGFASTNILTKESIVETVQ 78

Query: 75  MAIKLAKVSNA--EVPLYVGNPVEGKAI--IKQKKDFLDVDLEEKTKLGLEVEKMIRRDK 130
            A+KLAK ++   + P+   +         +K KKDF DV  EEK +L  ++E+ +    
Sbjct: 79  RAVKLAKSASKLRKEPIKFSDEYFHNVYYEVKMKKDFRDVPPEEKLELLKKIEEEVLSTN 138

Query: 131 IKTSR--FSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVA-RSADIMQTYWKSFGGTV 187
           +K      +YSD V  KI++NSE +V+E+V+PR+    + V      + Q  + S   + 
Sbjct: 139 VKVPMRYLAYSDHVWHKIFVNSENAVVESVIPRVSVMYNLVVYEEGQMEQAPFVSRAFSG 198

Query: 188 GWELVESVD-FNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246
           G EL+E  + +      + +    +   + PP G++ +++ PE+AG+ +HE++GH  E D
Sbjct: 199 GLELIEKDEPWERAKKEVETLKRIITEGKKPPEGKVDLVISPEVAGIAVHESVGHPYELD 258

Query: 247 SVRQGESILSG-------MIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIK 299
            +   E+  +G       M+G++IGSE +TVIDDPT+P  +G Y+YDDEG+  +   +I+
Sbjct: 259 RIMGREAAQAGESFVKPDMLGERIGSEVVTVIDDPTIPNSWGFYLYDDEGVKARPRYLIR 318

Query: 300 DGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFG 359
           +G++  +L +RE +  L L  N   RA +Y   P+VRM+NTY+APG+++ EE+ E++K G
Sbjct: 319 NGIITEFLMNREYAAKLGLRSNAAARAINYNREPIVRMANTYLAPGDYSFEELIEDIKLG 378

Query: 360 VYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDL 419
           VYM+      +D       +  +E Y+I+ GEIK  V+   +          + AVG+++
Sbjct: 379 VYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKHPVKRPILEITTRGLWSSVDAVGKEV 438

Query: 420 KIEFPGFCGK---GQWVPVDDGGPHVLVKAI 447
           +   PG CGK   GQ VPV  GG H  ++ I
Sbjct: 439 EFH-PGTCGKGEPGQGVPVWMGGAHARLRDI 468


>pir||D71135 tldD-related protein PH0848 - Pyrococcus horikoshii
           >gi|3257259|dbj|BAA29942.1| (AP000003) 481aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 481
           
 Score =  254 bits (642), Expect = 2e-66
 Identities = 156/453 (34%), Positives = 253/453 (55%), Gaps = 26/453 (5%)

Query: 18  FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSK--LEDTIK 74
           + + RFE        ++NG  EG+E   + GIGVRVL+NG  GFASTN L+K  + +T+K
Sbjct: 27  YAEARFEEKQGISLAMKNGIPEGMEILSDKGIGVRVLVNGGMGFASTNVLTKESIAETVK 86

Query: 75  MAIKLAKVSNA--EVPLYVGNPVEGKAI--IKQKKDFLDVDLEEKTKLGLEVEKMIRRDK 130
            A+KLAK ++   + P+             +K KKDF DV  EEK +L  ++E+ +    
Sbjct: 87  RAVKLAKAASKLRKEPITFSEEDFHNVYYEVKMKKDFRDVSPEEKLELLKKIEEEVTSTN 146

Query: 131 IKTSR--FSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT---YWKSFGG 185
           +       +YSD V  K+++NSE + IE+++PR+    + V      M+      ++F G
Sbjct: 147 VNVPMRYIAYSDHVWHKVFMNSENAKIESLIPRVSVMYNLVVFENGQMEQAPFIQRAFSG 206

Query: 186 TVGWELVESVD-FNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVE 244
             G EL+E  + +      + +    +   +  P G++ +I+ PE+AG+ +HE++GH  E
Sbjct: 207 --GLELIEKDEPWERAKREVETLRKIITEGKRSPEGKVDVIISPEVAGIAVHESVGHPYE 264

Query: 245 ADSVRQGESILSG-------MIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEI 297
            D +   E+  +G       M+G++IGSE +TVIDDPT+P  +G Y+YDDEG+  +   +
Sbjct: 265 LDRIMGREAAQAGESFVKPEMLGERIGSEVVTVIDDPTIPNSWGFYLYDDEGVKARPRYL 324

Query: 298 IKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVK 357
           I++G++  +L +RE +  L L  N   RA +Y   P+VRM+NTY+APG+++ EE+ E+VK
Sbjct: 325 IRNGIITEFLMNREYAAKLGLRSNAAARAINYNREPIVRMANTYLAPGDYSFEELIEDVK 384

Query: 358 FGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGR 417
            GVYM+      +D       +  +E Y+I+ GEIK  V+   +          + AVG+
Sbjct: 385 LGVYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKHPVKRPILEITTRGLWSSVDAVGK 444

Query: 418 DLKIEFPGFCGK---GQWVPVDDGGPHVLVKAI 447
           +++  + G CGK   GQ VPV  GG H  ++ I
Sbjct: 445 EVEF-YAGTCGKGEPGQGVPVWMGGAHARLRDI 476


>pir||D72762 hypothetical protein APE0089 - Aeropyrum pernix (strain K1)
           >gi|5103477|dbj|BAA78998.1| (AP000058) 489aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 489
           
 Score =  252 bits (637), Expect = 6e-66
 Identities = 159/462 (34%), Positives = 248/462 (53%), Gaps = 20/462 (4%)

Query: 5   LRNLIEKYSNE-VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFAS 62
           L  L+EK  ++   + + RF   +     V N +V G     E G+  RV+++G  GFAS
Sbjct: 26  LEKLVEKALDKGASYAEARFHARLGDSVLVVNDRVVGGGFEIEEGVAFRVIVDGALGFAS 85

Query: 63  TNDLSK--LEDTIKMAIKLAKVSNAEVPLYVGNPVE--GKA--IIKQKKDFLDVDLEEKT 116
           T+ LS+  L+  +  A+ +A+ S+      VG   E  G+A   +K KKDF +++LE+K 
Sbjct: 86  TSLLSEESLDSVVDHAVSIARSSSRGFRKKVGMSEERLGQAQYSLKVKKDFRNLELEDKA 145

Query: 117 KLGLEVEKMIRRDKI--KTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSAD 174
            + LE  K +    +  K   FSYSD +  K+ + S+G  IE+++PR+    +  A   D
Sbjct: 146 SIVLEYSKSLESKSVDLKAKTFSYSDVLEAKLIITSDGGNIESIIPRVSIFYNIAAEHGD 205

Query: 175 IMQTYWKSFGGTVGWELVESVDF-NYWANFISSKALSLLSARSPPSGEMPIIMDPELAGV 233
                W    G+ G ELV  +   +   + ++S  ++L+ A   P G M +I+ PE+ G+
Sbjct: 206 RRANKWGHLAGSGGLELVGELGLESMLKDDVNSLEVNLVKAEPSPKGVMDVIISPEIVGL 265

Query: 234 FIHEALGHAVEADSVRQGESILSGM-----IGKKIGSEELTVIDDPTLPGKFGSYVYDDE 288
            +HE++GH  EAD V   E+  +G+     +  +IGS ++TV DDPT+PG +G Y+YDDE
Sbjct: 266 ALHESIGHPSEADRVMGREAAQAGLSYRMWLDGRIGSSKVTVADDPTVPGSYGFYLYDDE 325

Query: 289 GLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWT 348
            +P +   +I  G L   L+ R T+ +  +  NG  RA +Y   P+VRMSNTY+ PG+  
Sbjct: 326 AVPARERILINKGELAELLHSRTTAYSFGVQSNGAARAMNYRSEPIVRMSNTYLKPGDMR 385

Query: 349 LEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDT 408
            EE+ E+VK G+YM       +D       +   E Y+IK G I + VRD  +       
Sbjct: 386 FEELLEDVKEGIYMKSYMEWNIDEFRLVARYVGLEAYLIKNGRIVKPVRDTVLEIPTESF 445

Query: 409 LKEIKAVGRDLKIEFPGFCGKG---QWVPVDDGGPHVLVKAI 447
             +I  VG+DL+  + G CGKG   Q +PV  GGPHV V+ +
Sbjct: 446 YSKIDGVGKDLRF-YAGICGKGEPPQPLPVWMGGPHVRVRDV 486


>gb|AAK40965.1| Zn-dependent protease, tldD protein homolog, putative (tldD)
           [Sulfolobus solfataricus]
           Length = 443
           
 Score =  238 bits (600), Expect = 1e-61
 Identities = 154/439 (35%), Positives = 238/439 (54%), Gaps = 18/439 (4%)

Query: 18  FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN-GWGFASTNDLSK--LEDTIK 74
           F DIR+E  I  E T+   + + V    + G  +RV+ N  WGF +T+ +++  +EDTI 
Sbjct: 15  FADIRYERVIANEVTITEDR-KYVSHGVDEGYSIRVIYNRNWGFKATDKITENEIEDTIN 73

Query: 75  MAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTS 134
                 +V+   +P        GK I K +++ ++ DL    K+  +V  +     IK+ 
Sbjct: 74  HIYGDERVNIVYLPSKHDTIKIGKDINKNEEEKIN-DLH---KVASQVNTL--HPSIKSY 127

Query: 135 RFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVES 194
              Y D +  K Y +SE   I         S+  VAR  D+     +     +G+ + + 
Sbjct: 128 SIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAREGDVTVEVSEILSTQMGY-IFDV 186

Query: 195 VDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESI 254
            D N     +  + ++ L   +P +GE P+I+ PE+ G+F HEA+GH  EAD    G   
Sbjct: 187 FDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVGIFTHEAIGHLSEADVTLNGS-- 244

Query: 255 LSGMIGKKIGSEELTVIDDPTLPGKFGSYVY-DDEGLPGKRVEIIKDGVLLNYLNDRETS 313
           L  +  K+IG E L + D P +     S VY DDEG+ G+ V+II++G+L  ++ DR  S
Sbjct: 245 LYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGREVKIIENGILKEFMTDRYYS 304

Query: 314 KALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIA 373
             L   P G+ RAQSY +  L+RM NTY+ PG+ +L E+FE +K G Y++   GG+   +
Sbjct: 305 AYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELFEGIKEGYYLVSPIGGETS-S 363

Query: 374 NGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFCGK-GQW 432
           NG+F F  +EGY ++  EIKE +R++GISGN + TL  I+ + +D  +   GFC K GQ 
Sbjct: 364 NGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEMISKDFGMS-SGFCEKNGQT 422

Query: 433 VPVDDGGPHVLVKAI-VGG 450
           V V +GGPH+ VK + VGG
Sbjct: 423 VQVSNGGPHIKVKKLKVGG 441


>emb|CAB57642.1| (Y18930) hypothetical protein [Sulfolobus solfataricus]
           Length = 443
           
 Score =  238 bits (600), Expect = 1e-61
 Identities = 154/439 (35%), Positives = 238/439 (54%), Gaps = 18/439 (4%)

Query: 18  FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN-GWGFASTNDLSK--LEDTIK 74
           F DIR+E  I  E T+   + + V    + G  +RV+ N  WGF +T+ +++  +EDTI 
Sbjct: 15  FADIRYERVIANEVTITEDR-KYVSHGVDEGYSIRVIYNRNWGFKATDKITENEIEDTIN 73

Query: 75  MAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTS 134
                 +V+   +P        GK I K +++ ++ DL    K+  +V  +     IK+ 
Sbjct: 74  HIYGDERVNIVYLPSKHDTIKIGKDINKNEEEKIN-DLH---KVASQVNTL--HPSIKSY 127

Query: 135 RFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVES 194
              Y D +  K Y +SE   I         S+  VAR  D+     +     +G+ + + 
Sbjct: 128 SIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAREGDVTVEVSEILSTQMGY-IFDV 186

Query: 195 VDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESI 254
            D N     +  + ++ L   +P +GE P+I+ PE+ G+F HEA+GH  EAD    G   
Sbjct: 187 FDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVGIFTHEAIGHLSEADVTLNGS-- 244

Query: 255 LSGMIGKKIGSEELTVIDDPTLPGKFGSYVY-DDEGLPGKRVEIIKDGVLLNYLNDRETS 313
           L  +  K+IG E L + D P +     S VY DDEG+ G+ V+II++G+L  ++ DR  S
Sbjct: 245 LYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGREVKIIENGILKEFMTDRYYS 304

Query: 314 KALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIA 373
             L   P G+ RAQSY +  L+RM NTY+ PG+ +L E+FE +K G Y++   GG+   +
Sbjct: 305 AYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELFEGIKEGYYLVSPIGGETS-S 363

Query: 374 NGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFCGK-GQW 432
           NG+F F  +EGY ++  EIKE +R++GISGN + TL  I+ + +D  +   GFC K GQ 
Sbjct: 364 NGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEMISKDFGMS-SGFCEKNGQT 422

Query: 433 VPVDDGGPHVLVKAI-VGG 450
           V V +GGPH+ VK + VGG
Sbjct: 423 VQVSNGGPHIKVKKLKVGG 441


>sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD protein - Escherichia
           coli (strain K-12) >gi|606183|gb|AAA58046.1| (U18997)
           ORF_f481 [Escherichia coli] >gi|1732437|dbj|BAA07913.1|
           (D44451) TldD protein [Escherichia coli]
           >gi|1789640|gb|AAC76276.1| (AE000403) suppresses
           inhibitory activity of CsrA [Escherichia coli K12]
           Length = 481
           
 Score =  231 bits (584), Expect = 1e-59
 Identities = 141/444 (31%), Positives = 239/444 (53%), Gaps = 14/444 (3%)

Query: 20  DIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKLEDTIKMA 76
           D+ F+++ +  + +E+  ++    N + G+GVR +     G+ +A    L  LE + + A
Sbjct: 37  DLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAA 96

Query: 77  IKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRR--DKIKTS 134
             + + S       +G  VE   +         +  EEK  +   V+K+ R    +++  
Sbjct: 97  RTIVRDSGDGKVQTLG-AVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEV 155

Query: 135 RFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWE---- 190
             S S      +   ++G++   V P +  S+S +       +      GG  G+E    
Sbjct: 156 TASLSGVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLA 215

Query: 191 -LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVR 249
            L   V  + WA      AL  LSA + P+G MP+++     GV +HEA+GH +E D  R
Sbjct: 216 DLDGEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNR 275

Query: 250 QGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLND 309
           +G S+ SG +G+ + SE  TV+DD T+  + GS   DDEG PG+   +I++G+L  Y+ D
Sbjct: 276 RGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQD 335

Query: 310 RETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQ 369
           +  ++ + + P G+GR +SYAH+P+ RM+NTY+ PG+ T +E+ E V++G+Y     GGQ
Sbjct: 336 KLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQ 395

Query: 370 VDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIE-FPGFCG 428
           VDI +G F+F   E Y+I+ G++ + V+   + G+ ++T+++I  VG DLK++   G CG
Sbjct: 396 VDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCG 455

Query: 429 K-GQWVPVDDGGPHVLVKAI-VGG 450
           K GQ +PV  G P + V  + VGG
Sbjct: 456 KEGQSLPVGVGQPTLKVDNLTVGG 479


>pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9654844|gb|AAF93595.1| (AE004129) tldD
           protein [Vibrio cholerae]
           Length = 481
           
 Score =  223 bits (563), Expect = 3e-57
 Identities = 142/465 (30%), Positives = 248/465 (52%), Gaps = 38/465 (8%)

Query: 13  SNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKL 69
           + ++ + DI F+++ +    +E+  ++    N + G+GVR +     G+ ++    L  L
Sbjct: 30  TRQIDYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAYSDQIQLEGL 89

Query: 70  EDTIKMAIKLAK---------VSNAEVPLYVG--NPVEGKAIIKQKKDFLDVDLEEKTKL 118
           + +   A  +A+            A+ P + G  NP+E              + ++KT+L
Sbjct: 90  KQSAIAARGIAQQGQNLTVQAFKRAQHPAFYGAHNPLESW------------EKQQKTEL 137

Query: 119 GLEVEKMIRRDK--IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIM 176
             +++  IR  +  I     S S    + +   ++G+    + P +  S+S +A+  D  
Sbjct: 138 LKQLDAYIRTKEPLITEVSVSLSGVHEQILVAATDGTYAGDIRPLVRLSISVLAQKGDRR 197

Query: 177 QTYWKSFGGTVGW------ELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPEL 230
           +      GG  G+      E  + + F++ A+    +AL  L A + P+G MP+++    
Sbjct: 198 ERGSAGGGGRFGYDYFLQEEAGQKIAFSF-ADEAIRQALVNLEAVAAPAGTMPVVLGSGW 256

Query: 231 AGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGL 290
            GV +HEA+GH +E D  R+G S+ +G +GKK+ S+  T++DD TL    GS   DDEG+
Sbjct: 257 PGVLLHEAVGHGLEGDFNRKGSSVFAGKVGKKVTSDLCTIVDDGTLKDLRGSLNVDDEGV 316

Query: 291 PGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLE 350
            G+   +I+ G+L  Y+ D+  ++ + + P G+GR +SYAH+P+ RM+NTY+ PGE T E
Sbjct: 317 SGQYNVLIEKGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPE 376

Query: 351 EMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLK 410
           E+   VK G+Y     GGQVDI +G F+F A E Y+I+ G+I   ++   + G+ ++ ++
Sbjct: 377 EIIASVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIENGKITRPIKGATLIGSGIEAMQ 436

Query: 411 EIKAVGRDLKIE-FPGFCGK-GQWVPVDDGGPHVLVKAI-VGGRE 452
           ++  VG DL ++   G CGK GQ VPV  G P + + A+ VGG E
Sbjct: 437 QVSMVGNDLALDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGTE 481


>sp|P73754|Y863_SYNY3 HYPOTHETICAL 50.4 KD PROTEIN SLR0863 >gi|7429837|pir||S74845 tldD
           homolog slr0863 - Synechocystis sp. (strain PCC 6803)
           >gi|1652888|dbj|BAA17806.1| (D90909) hypothetical
           protein [Synechocystis sp.]
           Length = 463
           
 Score =  220 bits (556), Expect = 2e-56
 Identities = 146/455 (32%), Positives = 238/455 (52%), Gaps = 14/455 (3%)

Query: 5   LRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFAST 63
           L  LI +Y ++  F+ IR E +  T+ ++ + +VE +     +G  VRV   G WGFAS 
Sbjct: 10  LPELIGRYQSQADFISIRLEQSEGTQISLRSDQVETLSEGIAMGGQVRVCHQGGWGFASF 69

Query: 64  NDLSKLEDTIKMAIKLAK-VSNAEVPLYVGNPVEGKAIIKQK-KDFLDVDLEEKTKLGLE 121
           N   +L   ++ AI  A+ + + E  L   +PV+   I     KD   + L +K  L   
Sbjct: 70  NRWEQLRQRLEEAIAAARLIGDDETLLAPIDPVQQTFINPLTGKDPRQISLADKKALCDH 129

Query: 122 VEKMIR--RDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTY 179
              ++R   DKI T+   YSD     +   SEG+++E     +    +A A+  + +Q  
Sbjct: 130 YNDLLRGTSDKITTTHVRYSDSQQTVLLATSEGTLLEQCWWDLEMRFAATAKDGNGVQVG 189

Query: 180 WKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEAL 239
            ++ G   G+  +E++D        + +A+  L+  +      P+++DP L G+F+HEA 
Sbjct: 190 RETTGSRRGYGDLENLD--QVVQGAAQRAVKALTLPTVQGKTYPVVIDPILTGLFVHEAF 247

Query: 240 GHAVEADSVRQGESILSGM-IGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298
           GH  EAD + +    L  M +G++ G  EL + D    PG  GSY +DDEG+P    ++I
Sbjct: 248 GHLSEADMLYENPDFLEVMSLGRRFGPPELQIFDGAAPPGHRGSYGFDDEGVPASTTQLI 307

Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358
           KDG L+  L+ RET+  L   P G+ R  +Y + P+VRM+NT+I  GE  +  + + ++ 
Sbjct: 308 KDGELVGRLHSRETAGKLGEKPTGNARCLNYHYPPIVRMTNTWIGRGETPVANLLDGIEE 367

Query: 359 GVYMIGDKGGQVDIANGS-FMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGR 417
           G+Y     GG   + NG  F F A E ++I+ G++ E V+DV +SGN+  TL  I+A+  
Sbjct: 368 GIYAQNWLGG---MTNGEMFTFSAGEAWMIRHGQLAEPVKDVTLSGNVFKTLANIEAIAD 424

Query: 418 DLKIEFPGFCGKG--QWVPVDDGGPHVLVKAIVGG 450
           D   +  G CGKG    + V  GGP + ++ +V G
Sbjct: 425 DFYWDESGGCGKGGQNGLAVGCGGPSLRIRDVVVG 459


>gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum]
           Length = 479
           
 Score =  219 bits (552), Expect = 5e-56
 Identities = 139/425 (32%), Positives = 230/425 (53%), Gaps = 9/425 (2%)

Query: 34  ENGKVEGVESNEEVGIGVR-VLINGWGFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVG 92
           +NG+++    +   G G+R V  +  G+A ++D+S L   I+ A  +A V       +  
Sbjct: 53  DNGRLKQATYDTSQGFGLRAVKDDAVGYAHSSDVS-LPALIRAADAVAAVRGGYSGSFSA 111

Query: 93  NPVEGKAIIKQKKDFLDVD-LEEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTRKIY--LN 149
            P      +    + LD    E K KL  E++  +R    +  + S +   T ++   L 
Sbjct: 112 PPPHTNVRLYGDDNPLDAPGFETKVKLLAEIDAYLRDKDPRVRQVSVTLGATWQVVEILR 171

Query: 150 SEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGW-ELVESVDFNYWANFISSKA 208
            +G     + P +  ++S VA   D  ++  K +GG  G+ E +ES ++   A+    +A
Sbjct: 172 PDGESYRDIRPLVRVNISVVAGQGDRQESGSKGYGGRAGYAEFIESKNWRDAADGALREA 231

Query: 209 LSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEEL 268
           L  L +   P+GEM +++     GV +HEA+GH +E D  R+  S  +G++G+++ ++ +
Sbjct: 232 LVNLESIPAPAGEMDVVLGAGWPGVMLHEAVGHGLEGDFNRKRTSAFAGLMGRQVAAKGV 291

Query: 269 TVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQS 328
           TV+DD T+  + GS   DDEG P  R  +I+DG+L+ Y+ DR+ ++ +N+ P G+GR Q 
Sbjct: 292 TVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGILVGYMQDRQNARLMNMKPTGNGRRQG 351

Query: 329 YAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIK 388
           YAHVP+ RM+NTY+  G+    E+   VK GV+     GGQVDI +G ++F   E Y I+
Sbjct: 352 YAHVPMPRMTNTYMLAGDRDPAEILASVKNGVFAANFGGGQVDITSGKYVFQCTEAYKIE 411

Query: 389 EGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFP-GFCGK-GQWVPVDDGGPHVLVKA 446
            G+I   ++   + GN    L  I+ +G DL ++   G CGK GQ VPV  G P +L++ 
Sbjct: 412 NGKIGAPLKGAMLIGNGPTDLHRIRMIGNDLALDTGIGTCGKNGQGVPVGVGQPSLLMER 471

Query: 447 I-VGG 450
           I VGG
Sbjct: 472 ITVGG 476


>pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07784.1|
           (AE000768) TldD protein [Aquifex aeolicus]
           Length = 404
           
 Score =  217 bits (548), Expect = 2e-55
 Identities = 126/387 (32%), Positives = 210/387 (53%), Gaps = 12/387 (3%)

Query: 17  KFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING---WGFASTNDLSKLEDTI 73
           ++ +I +E +  T   +E+ K++ V    + G+G+R++ NG   +G+ +      L++  
Sbjct: 19  EYGEIFYEKSRTTRMHLEDRKIDKVTHGYDEGVGLRLIKNGKTYYGYTTNPTFENLKELA 78

Query: 74  KMAIKLAKVSNAEVPLYVGNP-VEG--KAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDK 130
           K+  +         P+ +G   ++G  + +I   K+ L    E   +   +       DK
Sbjct: 79  KILAR----GEGHGPVAIGKRYIQGYTEVLIDPDKESLKFRAEILRRADEKARSF--GDK 132

Query: 131 IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWE 190
           IK       D     + +N+ G   E    R+ F +  VA   + +Q  ++S GG  G+E
Sbjct: 133 IKQVLAVLMDKTREIMVINTLGETAEDTQKRVVFFVEVVASDGETLQRGYESLGGRRGFE 192

Query: 191 LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQ 250
           +         A   + +AL +LSA+  P+G   ++M  +  G  IHEA+GH +EAD V+Q
Sbjct: 193 IFNETPPEVIAEKAAKRALLMLSAKPAPAGTFTVVMSSQAGGTMIHEAVGHGLEADLVQQ 252

Query: 251 GESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDR 310
           G S+ +G +G+K+ SE +TVIDD TLP   GS+  DDEG+P +R  +IKDGVL+ Y+ DR
Sbjct: 253 GLSVYAGKLGEKVASELVTVIDDATLPYHNGSFTVDDEGVPAQRKVLIKDGVLVGYMYDR 312

Query: 311 ETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV 370
             +    +   G+GR QSYAH+P+VRM+NT+I  G+   E++ ++ K GV ++   GG+V
Sbjct: 313 LRAMKDGVESTGNGRRQSYAHIPIVRMTNTFIDKGQDNPEDIIKDTKKGVLVVKMGGGEV 372

Query: 371 DIANGSFMFGAKEGYIIKEGEIKEQVR 397
           +   G F+F   EGY+I+ GEI   +R
Sbjct: 373 NTVTGDFVFEVMEGYMIENGEITYPIR 399


>pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa (strain 9a5c)
           >gi|9106089|gb|AAF83937.1|AE003949_1 (AE003949) TldD
           protein [Xylella fastidiosa]
           Length = 485
           
 Score =  215 bits (542), Expect = 8e-55
 Identities = 138/455 (30%), Positives = 246/455 (53%), Gaps = 24/455 (5%)

Query: 16  VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTIK 74
           V F D+ F++     +++E+G V+    + E G+GVR +     GFA ++D+++ +  ++
Sbjct: 36  VDFGDLYFQHARRESWSIEDGIVKDGTHSIEQGVGVRAISGEKTGFAYSDDINR-DALLE 94

Query: 75  MAIKLAKVSNAEVPLYVGNPVEGK--AIIKQKKDF-----LD----VDLEEKTKLGLEVE 123
            A     +S +      G+ V+G    ++ Q+++      LD    +D  EK  +   V+
Sbjct: 95  AAYAARAISRSP-----GDGVQGTHAVLLHQERELCLYPALDPVGGMDNAEKIAVMRRVD 149

Query: 124 KMIRR--DKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWK 181
           +++R    ++     + S  V   +   S+G +   V P +  ++  +       ++ + 
Sbjct: 150 QLLRAADPRVTQVMVNLSGGVDVVLIARSDGVLAADVRPLVRLNVQVIVEGHGRRESGYA 209

Query: 182 SFGGTVGW-ELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALG 240
             GG  G+ EL        +A     +AL  L A   P+G MP+++     GV +HEA+G
Sbjct: 210 GGGGRYGYAELFADGRPEAFAREALRQALVNLEAIPAPAGVMPVVLGAGWPGVLLHEAVG 269

Query: 241 HAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKD 300
           H +E D  R+G S+ +G IG+++ S  +T++DD TL G+ GS   DDEG P +   +I+D
Sbjct: 270 HGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPTQCTTLIED 329

Query: 301 GVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGV 360
           GVL+ Y+ D   ++ + +   G+GR +S+AH+ + RM+NTY+  G  + EEM   VK G+
Sbjct: 330 GVLVGYMQDTLNARLMGVASTGNGRRESFAHLTMPRMTNTYMRAGVHSREEMIRSVKKGL 389

Query: 361 YMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420
           Y +   GGQVDI +G ++F A E Y+I++G +   ++   + GN  +T++ ++ +G DL 
Sbjct: 390 YAVNFGGGQVDITSGKYVFSATEAYLIEDGRVTAPIKGATLIGNGPETMQRVRMIGDDLA 449

Query: 421 IEF-PGFCGK-GQWVPVDDGGPHVLVKAI-VGGRE 452
           ++   G CGK GQ VPV  G P +L+  + VGG +
Sbjct: 450 LDAGVGVCGKDGQSVPVGVGQPSLLIDGLTVGGTQ 484


>sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13101.1| (AP001119) tldD
           protein [Buchnera sp. APS]
           Length = 483
           
 Score =  215 bits (542), Expect = 8e-55
 Identities = 140/469 (29%), Positives = 241/469 (50%), Gaps = 38/469 (8%)

Query: 8   LIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVL---INGWGFASTN 64
           L E  + ++ + D+ F++ I+  + +EN  ++    + + GIGVR +     G+ ++   
Sbjct: 25  LEELCTRQLDYGDLYFQSHIHESWILENSIIKEGNYHSDAGIGVRAIRGESTGFAYSDQI 84

Query: 65  DLSKLEDTIKMA--IKLAKVSNAEV--------PLYVG-NPVEGKAIIKQKKDFLDVDLE 113
            L  L  + K A  I L K S            P+Y   NP+EG               +
Sbjct: 85  SLDSLRRSTKKAHSIILTKGSGKTKTLSKKTIEPIYKNVNPLEG------------FSSK 132

Query: 114 EKTKLGLEVEKMIRR--DKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVAR 171
           EKT L      + R    ++     S +    + +  +++G+++  + P I FS+S +  
Sbjct: 133 EKTDLLYRANYIARSLDHRVIEVNASLTGSYEQILVASTDGNLVSDIRPSIQFSISVLVE 192

Query: 172 SADIMQTYWKSFGGTVGWELVESVD-------FNYWANFISSKALSLLSARSPPSGEMPI 224
                +      G    +    + D        ++W+      AL  LS++   SG  P+
Sbjct: 193 DHGKRERGRSGGGSRTDYNFFLNQDDSSKEIRIDHWSKEAVRIALLNLSSKEALSGTFPV 252

Query: 225 IMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYV 284
           ++     GV +HEA+GH +E D  R+G SI + MIGKK+ SE  T+IDD T+  + GS  
Sbjct: 253 VLGSGWPGVLLHEAIGHGLEGDFNRKGTSIFTNMIGKKVASELCTIIDDGTIKNQRGSLS 312

Query: 285 YDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAP 344
            DDEG PG++  +I++G+L  Y+ D+  ++ + +   G+GR +SY+ +P+ RM+NTY+  
Sbjct: 313 IDDEGTPGQKNILIENGILKKYMQDKLNARLMGVKSTGNGRRESYSCLPMPRMTNTYMLS 372

Query: 345 GEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGN 404
           G+  L+++ + V +G+Y +   GGQVDI +G F+F   E Y+IK G+I   +++  + G+
Sbjct: 373 GKSKLDDIIKSVDYGIYAVNFSGGQVDITSGKFVFSTSEAYLIKNGKIVTPIKNTTLIGS 432

Query: 405 ILDTLKEIKAVGRDLKI-EFPGFCGK-GQWVPVDDGGPHV-LVKAIVGG 450
            L+ +++I  VG DLK+ E  G CGK GQ +PV  G P + L    +GG
Sbjct: 433 GLEVMQKISMVGDDLKMDEGMGICGKDGQNIPVGIGQPSMKLENLTIGG 481


>pir||D72342 tldD protein - Thermotoga maritima (strain MSB8)
           >gi|4981251|gb|AAD35808.1|AE001743_10 (AE001743) tldD
           protein [Thermotoga maritima]
           Length = 499
           
 Score =  209 bits (527), Expect = 5e-53
 Identities = 142/445 (31%), Positives = 227/445 (50%), Gaps = 16/445 (3%)

Query: 18  FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWG-FASTNDLSKLEDTIKMA 76
           F ++ FE      + +++GK+E   S E VG+G+R  +     +A TNDLS+ E+ I +A
Sbjct: 58  FAELFFERKYENRYELKDGKIEQATSGEIVGVGIRGFLGTKAVYAYTNDLSR-ENLINVA 116

Query: 77  IKLAKV---SNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDK--- 130
            K+ +    +  E   +  N  + K   ++    +     EKT     ++K     K   
Sbjct: 117 KKVGEALGETKVEDLTFNFNRTKRK---ERHVVLIPPAQVEKTDKVSVMKKAYYAAKNYS 173

Query: 131 --IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVG 188
             IK     Y D+    +  NSEG+  E    R    ++AVA    +++  +   G  +G
Sbjct: 174 ELIKQVVVWYWDYDQEILVANSEGTWAEDRRVRTRLMINAVAEKDGVLERGFYGPGAGMG 233

Query: 189 WELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSV 248
           +E  + +D    A   +  A  ++ A   P+G+M +++     GV  HEA+GH +EA SV
Sbjct: 234 FEFFDRIDVEEAAKKAARIAARMVEAEPAPAGKMTVVIANGFGGVIFHEAVGHGLEATSV 293

Query: 249 RQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLN 308
            +G S+ +G +G+K+ +E ++ +DD T+P  +GS   DDEG P +R  +I  GVL+ YL 
Sbjct: 294 AKGASVFAGKLGQKVAAECVSAVDDATIPNGWGSANVDDEGTPTQRTLLIDKGVLVGYLV 353

Query: 309 DRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGG 368
           D+   + + +   G GR Q Y   P  RMSNT+I PG++  EE+    ++G+Y     GG
Sbjct: 354 DKLGERRMGMKSTGSGRRQDYTFPPTSRMSNTFILPGDYHPEEIIAATEYGLYAKTMGGG 413

Query: 369 QVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFCG 428
            V+ A G F F   E Y+I++G I + VR   + G   + +++I  VG DL  +  G CG
Sbjct: 414 SVNPATGEFNFAVSEAYLIEKGRITKPVRGATLIGKGHEIIQKIDMVGNDLARD-QGMCG 472

Query: 429 K-GQWVPVDDGGPHVLVKAI-VGGR 451
                VP D G P + VK I VGGR
Sbjct: 473 SFSGSVPADVGQPTIRVKEIVVGGR 497


>pir||D83086 conserved hypothetical protein PA4474 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9950711|gb|AAG07862.1|AE004861_3 (AE004861)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 480
           
 Score =  205 bits (516), Expect = 9e-52
 Identities = 144/463 (31%), Positives = 238/463 (51%), Gaps = 19/463 (4%)

Query: 2   IDELRNLIEKYSNE-VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WG 59
           +D L  ++ + +   +   D+ F++ +   + +E+G V+    N + G+GVR       G
Sbjct: 20  LDSLPGILHELNGPGIDAADLYFQSQVSESWMLEDGIVKEGSFNLDQGVGVRAQSGEKTG 79

Query: 60  FASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQK----KDFLDV-DLEE 114
           FA +N ++  E   + A+    +S A      G+    KA++  +    ++ LDV    E
Sbjct: 80  FAYSNAITA-EALKQAAVAARSISRAGQN---GSVQAFKAVVPARLYAGENPLDVLSRAE 135

Query: 115 KTKLGLEVEKMIRR--DKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARS 172
           K +L  +++   R    +I+    S +    + +   S+GS+   + P + F++S +   
Sbjct: 136 KVELLKQIDAATRALDPRIQQVTVSMAGVWEQILVAASDGSLAADIRPLVRFNVSVIVEQ 195

Query: 173 ADIMQTYWKSFGGTVGWE--LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPEL 230
               +      GG   +   L E     Y A     +AL  L A   P+G +P++M    
Sbjct: 196 NGRRERGGHGGGGRTDYRYFLQEDRAMGY-AREALRQALVNLEAIPAPAGTLPVVMGAGW 254

Query: 231 AGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGL 290
           +GV +HEA+GH +E D  R+G S  SG +G+K+ S   T++DD TL G+ GS   DDEG 
Sbjct: 255 SGVLLHEAVGHGLEGDFNRKGSSAYSGRVGEKVASSLCTIVDDGTLAGRRGSLSVDDEGT 314

Query: 291 PGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLE 350
           P     +I++GVL  Y+ D+  ++ + +   G+GR +SYAH+P+ RM+NTY+  GE   +
Sbjct: 315 PSNCNVLIENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLAGESDPQ 374

Query: 351 EMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLK 410
           E+   V+ G+Y     GGQVDI +G F+F   E Y+I+ G I   V+   + GN  + + 
Sbjct: 375 EIIASVEKGIYCANLGGGQVDITSGKFVFSTSEAYLIENGRITTPVKGATLIGNGPEAMS 434

Query: 411 EIKAVGRDLKIEF-PGFCGK-GQWVPVDDGGPHVLVKAI-VGG 450
            +  VG DL ++   G CGK GQ VPV  G P + + AI VGG
Sbjct: 435 RVSMVGNDLALDSGVGTCGKDGQSVPVGVGQPTLKIDAITVGG 477


>sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG
           Length = 482
           
 Score =  199 bits (500), Expect = 7e-50
 Identities = 133/464 (28%), Positives = 243/464 (51%), Gaps = 21/464 (4%)

Query: 5   LRNLIEKYSNE-VKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGF 60
           L N+ +  S+  + + D+ F+ +    + +E+G ++    + + G+GVR +     G+ +
Sbjct: 20  LLNIFDIMSHRNIDYADLYFQLSQDESWVLEDGIIKEGSFHIDRGVGVRAVSGEKTGFAY 79

Query: 61  ASTNDLSKLEDTIKMAIKLAKVSNAEV----PLYVGNPVEGKAIIKQKKDFLDVDLEEKT 116
           A   +L+ L+   +    +A+V    +       V NP+   A I   +       E+K 
Sbjct: 80  ADQINLASLQQCAEAVKGIAQVKQGNLISPSAFNVVNPIARYAAINPLESLTK---EKKI 136

Query: 117 KLGLEVEKMIRRDKIKTSRFS--YSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSAD 174
           +L   V++  R +  + ++ S   S      + + ++G++   + P +  S+S +     
Sbjct: 137 ELLHLVDRTARAEDHRVTKVSASLSSVYEEVLIMATDGTLAADIRPLVRLSISVLVEENG 196

Query: 175 IMQTYWKSFGGTVGWE-LVESVDFNYWANFISSKA----LSLLSARSPPSGEMPIIMDPE 229
             +      GG  G +   E VD +  A   + +A    L  LSA + P+G MP+++   
Sbjct: 197 KRERGSCGSGGRFGLDWFFEVVDGDIRAVLFAKEAVRQALVNLSAVAAPAGLMPVVLGAG 256

Query: 230 LAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEG 289
             GV +HEA+GH +E D  R+  S+ +G IG+++ S   T++DD T+  + GS   DDEG
Sbjct: 257 WPGVLLHEAVGHGLEGDFNRKESSLFTGKIGEQVTSPLCTIVDDGTIENRRGSLTIDDEG 316

Query: 290 LPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTL 349
           +P +   +IKDG+L  Y+ D+  ++ + +   G+GR +SYAH+P+ RM+NTY+  G+   
Sbjct: 317 VPSQCNVLIKDGILQGYMQDKMNARLMGVSTTGNGRRESYAHLPMPRMTNTYMLAGQSQF 376

Query: 350 EEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTL 409
           +++   VK G+Y     GGQVDI +G F+F   E Y+I++G+I + V+   + G+ ++ +
Sbjct: 377 DDLIASVKQGIYAPHFGGGQVDITSGKFVFSTSEAYLIEKGKITKPVKGATLIGSGIEVM 436

Query: 410 KEIKAVGRDLKIEFP-GFCGK-GQWVPVDDGGPHVLVKAI-VGG 450
           ++I  V    +++   G CGK GQ VPV  G P + +  I VGG
Sbjct: 437 QKISMVADKSELDLGIGVCGKEGQSVPVGVGQPALKIDEITVGG 480


>pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria meningitidis
           (group A strain Z2491) >gi|7379119|emb|CAB83668.1|
           (AL162752) TLDD protein homolog [Neisseria meningitidis
           Z2491]
           Length = 480
           
 Score =  191 bits (481), Expect = 1e-47
 Identities = 127/450 (28%), Positives = 225/450 (49%), Gaps = 16/450 (3%)

Query: 13  SNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKL 69
           ++ V + DI  + T Y  + +E G V+        G+GVR +      + +A +  +  +
Sbjct: 32  AHHVDYADIYCQRTAYESWHLEEGIVKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDSI 91

Query: 70  EDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRR- 128
             + + A++    +  +V   + +   GK +         +D   K  L  +VE + +  
Sbjct: 92  NRSAR-AVRAIGAAGGKVSAKMPSETRGKPVCSASDPIAGLDSAAKVALLNKVEAIAKAA 150

Query: 129 DKIKTSRFSYSDFVTRKIYL-NSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTV 187
           D       +        +YL   +G     + P +  +++ +A+  +  +    S GG  
Sbjct: 151 DPRIVQVMAGLTCEYDMVYLARLDGKHAADIRPMVRLNVTVIAKQGERREQ--GSAGGGG 208

Query: 188 GWELVESVDFNYWANFISS---KALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVE 244
            ++L    D N    F+ +   +AL+ L +R  P+GEM +++     GV +HEA+GH +E
Sbjct: 209 RYDLAY-FDENLVRQFVDAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLE 267

Query: 245 ADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLL 304
            D  R+G S+ SG IG+++ ++ +TV+D   + G+ GS   DDEG   +R  +I+DG+L+
Sbjct: 268 GDFNRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILV 327

Query: 305 NYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIG 364
            Y+ D   ++       G+GR +SYA  P+ RM+NT++  G +  EE+   +  G+Y + 
Sbjct: 328 GYMQDETNARLTGTQSTGNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVN 387

Query: 365 DKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEF- 423
             GGQVDI +G F+F A E + ++ G ++  V+   I GN  + LK +  +G D  ++  
Sbjct: 388 FGGGQVDITSGKFVFSASEAWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSG 447

Query: 424 PGFCGK-GQWVPVDDGGPHVLVKA--IVGG 450
            G CGK GQ VPV  G P + + A   VGG
Sbjct: 448 VGVCGKEGQSVPVGVGQPTLRIDAGLTVGG 477


>pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningitidis  (group B
           strain MD58) >gi|7227328|gb|AAF42385.1| (AE002556) tldD
           protein [Neisseria meningitidis MC58]
           Length = 480
           
 Score =  191 bits (480), Expect = 1e-47
 Identities = 122/447 (27%), Positives = 220/447 (48%), Gaps = 10/447 (2%)

Query: 13  SNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKL 69
           ++ V + DI  + T Y  + +E G V+        G+GVR +      + +A +  +  +
Sbjct: 32  AHHVDYADIYCQRTAYESWHLEEGIVKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDSI 91

Query: 70  EDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRR- 128
             + + A++    +  +V   + +   GK +         +D   K  L  +VE + +  
Sbjct: 92  NRSAR-AVRAIGAAGGKVSAKMPSETRGKPVCSASDPIAGLDSAAKVALLNKVEAIAKAA 150

Query: 129 DKIKTSRFSYSDFVTRKIYL-NSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTV 187
           D       +        +YL   +G     + P +  +++ +A+  +  +      GG  
Sbjct: 151 DPRIVQVMAGLTCEYDMVYLARLDGKHAADIRPMVRLNVTVIAKQGERREQGSAGGGGRY 210

Query: 188 GWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADS 247
                +    + + +    +AL+ L +R  P+GEM +++     GV +HEA+GH +E D 
Sbjct: 211 DLAYFDENLVHRFVDAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLEGDF 270

Query: 248 VRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYL 307
            R+G S+ SG IG+++ ++ +TV+D   + G+ GS   DDEG   +R  +I+DG+L+ Y+
Sbjct: 271 NRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILVGYM 330

Query: 308 NDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKG 367
            D   ++       G+GR +SYA  P+ RM+NT++  G +  EE+   +  G+Y +   G
Sbjct: 331 QDETNARLTGTQSTGNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVNFGG 390

Query: 368 GQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEF-PGF 426
           GQVDI +G F+F A E + ++ G ++  V+   I GN  + LK +  +G D  ++   G 
Sbjct: 391 GQVDITSGKFVFSASEAWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSGVGV 450

Query: 427 CGK-GQWVPVDDGGPHVLVKA--IVGG 450
           CGK GQ VPV  G P + + A   VGG
Sbjct: 451 CGKEGQSVPVGVGQPTLRIDAGLTVGG 477


>emb|CAC11942.1| (AL445065) conserved hypothetical protein [Thermoplasma
           acidophilum]
           Length = 455
           
 Score =  185 bits (465), Expect = 9e-46
 Identities = 127/453 (28%), Positives = 218/453 (48%), Gaps = 16/453 (3%)

Query: 5   LRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING--WGFAS 62
           L  +++   ++  F D RF         + NG+ +    + + G  +RV+ +     +  
Sbjct: 2   LDRILDYAGSKSAFADARFMEIEGRGAVIRNGEFDESLYSNDSGYAIRVVNDSIAMAYVD 61

Query: 63  TNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEV 122
           + D  K+   +  A+ L      +  +Y G   +            D  L +   +  E 
Sbjct: 62  SEDWDKVRAVVDDAV-LRSRRPGKNRIYRGRSEKASWSEIGSDHVRDHSLGDMIAILKEA 120

Query: 123 EKMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKS 182
           + +     ++ S  + SD    ++Y N++GS +E    RI+F+        D  +   + 
Sbjct: 121 DSVAEEANVRIS--ALSDRFVHQVYENTDGSHVEGTYSRIFFNYLVGVSENDRYEQSSEE 178

Query: 183 FGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHA 242
           FG T G++  +    +       S    ++ A S   G   +I+ PE++G+  HE+ GH 
Sbjct: 179 FGWTGGYDAFDFKTISETMKNDVSNLREIILAPSVEPGNFDVIVGPEISGIVAHESAGHP 238

Query: 243 VEADSVRQGESILSG---MIGK----KIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRV 295
            E D +   E+ L+G   + GK    +IGSE+++VIDDPTL G +G Y+YDDEG+  ++ 
Sbjct: 239 TEYDRIAGREAALAGESFLTGKTFPYRIGSEKVSVIDDPTLKGSYGYYLYDDEGVRARKR 298

Query: 296 EIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEE 355
            + ++G    +L +RE++  +    NG GR+ S+   PL RMS TYI PG+++ EE+FE 
Sbjct: 299 YLYRNGYTSEFLINRESAAWIGQESNGSGRSSSWDMEPLARMSTTYIEPGDYSFEELFEG 358

Query: 356 VKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAV 415
           V  G+Y+       +D    +  +  KE Y I+ G+IK +VR   +  N +     + AV
Sbjct: 359 VHRGIYIKSFTEWNIDDIRFNERYVGKEAYYIENGDIKGRVRRPILETNTIKFYSAVDAV 418

Query: 416 GRDLKIEFPGFCGKG---QWVPVDDGGPHVLVK 445
           G+DL     G CGKG   Q V V  GGPH+ ++
Sbjct: 419 GKDLHFS-AGICGKGDPEQGVEVWMGGPHMRLR 450


>gb|AAK41402.1| Conserved hypothetical protein [Sulfolobus solfataricus]
           Length = 458
           
 Score =  182 bits (458), Expect = 6e-45
 Identities = 138/457 (30%), Positives = 227/457 (49%), Gaps = 22/457 (4%)

Query: 4   ELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFAS 62
           +L++L +K+     ++++R         +  NG++ G     + G  VR   +G   FAS
Sbjct: 3   DLQSLYDKF--RYPYVEVRRHIVSTFGMSFLNGRLMGSFRFTDDGYSVRYYKDGVLYFAS 60

Query: 63  TNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEV 122
           +N+ + L  + K      K+   E  L    P EG   +K+ K F  + ++EK      +
Sbjct: 61  SNNPNDLLSSNKEY----KIEGWESGLDNTEPKEGSYEVKEGKPFDLMSVDEKISFFKNL 116

Query: 123 EKMIRRDK-IKTSRFSYSDFVTRK-IYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYW 180
            + ++  + +K+  F Y + +  K I +N  GS I   VPR+Y  ++ V    +   T +
Sbjct: 117 YEAVKDFRSVKSVSFFYDESIEEKEIIVN--GSRIVGRVPRLYVGMNLVLNENNRTATAF 174

Query: 181 KSFGGTVGWELVESVDFN-YWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEAL 239
              GG+ G E++E ++ N    + + S    L   +S       +++   L G+  HE++
Sbjct: 175 YELGGSGGLEVLERMNLNEVVVDKVRSVTEVLAKGKSFGERTTDVVLSNMLTGIMAHESV 234

Query: 240 GHAVEADSV------RQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGK 293
           GH  EAD V      + G S L+ +   +IGS+ +TVIDDPT+P   G Y  DDEG+  +
Sbjct: 235 GHPFEADRVLGREFAQAGLSYLAELKDNRIGSDVVTVIDDPTIPNSGGYYTTDDEGVEAR 294

Query: 294 RVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMF 353
              +IKDG +  YL +R +S   N+  NG  RA ++   PL+RMSNT+  PG  T +E+ 
Sbjct: 295 PKYLIKDGKVNEYLQNRFSSSKFNVKSNGSARAANFDREPLIRMSNTFFKPGNMTFDELL 354

Query: 354 EEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIK 413
           E+VK GVY+       +D       +   E Y IK G+I + V      G   + LK + 
Sbjct: 355 EDVKEGVYIKSYMEWNIDDMRLGQRYVGLEAYEIKNGKIGDPVLFPVFQGKTTELLKAVD 414

Query: 414 AVGRDLKIEFPGFCGKG---QWVPVDDGGPHVLVKAI 447
           AV   L + +PG CGKG   Q +PV  GGP++ ++ +
Sbjct: 415 AVDNTL-VFYPGTCGKGDPDQGIPVWLGGPNMRLRNV 450


>pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment)
           Length = 313
           
 Score =  173 bits (433), Expect = 5e-42
 Identities = 105/314 (33%), Positives = 169/314 (53%), Gaps = 16/314 (5%)

Query: 148 LNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVESVDFNYWANFISS- 206
           L  +G     + P +  ++S VA   D  ++  K +GG  G+      +FN  A+ ++  
Sbjct: 2   LRPDGESYRDIRPLVRVNISVVAGQGDRQESGSKGYGGRAGY-----AEFNLRASNLART 56

Query: 207 ------KALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIG 260
                 +AL  L +   P+GEM +++     GV +HEA+GH +E D  R+  S  SG++G
Sbjct: 57  PPTALREALVNLESIPAPAGEMDVVLGAGWPGVMLHEAVGHGLEGDFNRKRTSAFSGLMG 116

Query: 261 KKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVP 320
           +++ ++ +TV+DD T+  + GS   DDEG P  R  +I+DG+L+ Y+ DR+ ++ +N+ P
Sbjct: 117 RQVAAKGVTVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGILVGYMQDRQNARLMNMKP 176

Query: 321 NGHGRAQSYAHVPLVRMSNTYIAPG-EWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMF 379
            G+  A+ YAHVP+ RM+NTY+  G   +   +   VK         GGQVDI +G ++ 
Sbjct: 177 TGNAAARRYAHVPMPRMTNTYMLRGRSRSGRGVLASVKNAASRANFGGGQVDITSGKYVS 236

Query: 380 GAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFP-GFCGK-GQWVPVDD 437
              E Y  + G+         + GN    L  I+ +G DL ++   G CGK GQ VPV  
Sbjct: 237 QCTEAYKSENGKSGGPAEGRMLIGNGPTDLHRIRMIGNDLALDTGIGTCGKNGQGVPVGV 296

Query: 438 GGPHVLVKAI-VGG 450
           G P +L++ I VGG
Sbjct: 297 GQPSLLMERITVGG 310


>dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity of the cabon
           storage regulator (CsrA) [Bacillus halodurans]
           Length = 432
           
 Score =  158 bits (395), Expect = 1e-37
 Identities = 95/257 (36%), Positives = 136/257 (51%), Gaps = 8/257 (3%)

Query: 192 VESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQG 251
           V+  D      + ++ A+  L AR  PSG   +I+ P  A    HE +GH +EAD     
Sbjct: 170 VQEEDLQELVLYTANAAMEKLDARPFPSGSYALILGPLAAPGIFHEVVGHGLEADIASIP 229

Query: 252 ESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRE 311
           +S     +G  +G E++T+IDDPT  G  GSY  DDEG   ++  +I+ G ++NYL+   
Sbjct: 230 QSAFHQRLGAMVGCEKVTIIDDPTKEGLPGSYSLDDEGTIAQQTTLIEKGRVVNYLSHLH 289

Query: 312 TSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVD 371
           T        NGHGR  +Y H+PLVRMSNT++ PG    EEM  + + G+Y+     G V+
Sbjct: 290 TGHP----TNGHGRVINYQHLPLVRMSNTFLLPGTDDPEEMVSDTEVGLYVKKAINGDVN 345

Query: 372 IANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKI--EFPGFCGK 429
           +  G F     EGY+I++G+I   +    + G+    L+ I  VG D  I  E  G CGK
Sbjct: 346 MITGEFEIHVAEGYLIEKGQITSPILPTTLKGDGQKLLQSIDRVGNDFAIHSEVRGGCGK 405

Query: 430 -GQW-VPVDDGGPHVLV 444
            GQ  +PV  G P V V
Sbjct: 406 LGQSPLPVSAGSPTVRV 422


>sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|7429840|pir||S75512
           hypothetical protein slr1322 - Synechocystis sp. (strain
           PCC 6803) >gi|1653157|dbj|BAA18073.1| (D90911)
           hypothetical protein [Synechocystis sp.]
           Length = 489
           
 Score =  153 bits (383), Expect = 4e-36
 Identities = 123/447 (27%), Positives = 196/447 (43%), Gaps = 15/447 (3%)

Query: 18  FMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN-GWGFASTNDLS------KLE 70
           F++   E   Y     E+  +  +      G GVRV    G  + STND+S       LE
Sbjct: 45  FVEFFLEKVNYVSCLAEDDAITSLTPRLSSGCGVRVYKGKGDCYVSTNDISFNGLRTALE 104

Query: 71  DTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLD--VDLEEKTKLGLEVEKMIRR 128
             + +         + VP      +   A  K+K  +L     ++E + + L   + +  
Sbjct: 105 KGLSILGLTLPAGQSFVPELNLEMLRDYAGAKEKDQWLHRCSPMQEMSDILLGANQKLDH 164

Query: 129 --DKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGT 186
                ++ R +Y       +   S+G+    +        S      +   +  K  G T
Sbjct: 165 YASHAQSRRAAYFRDWQEVLVAASDGTFARDIRLTQSVGFSLFCADGEHRTSIGKRSGDT 224

Query: 187 VGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246
              + + + D    A  ++  A  +L A    SG  PIIM  +  GV  HEA GH +E  
Sbjct: 225 SNPDYLRTWDAETSAQEVAESAGKMLYADYVESGNYPIIMANQFGGVIFHEACGHLLETT 284

Query: 247 SVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNY 306
            +    +      G+KI  E LT  D+      FG+   DDEG+P +R  +I++G+L N+
Sbjct: 285 QIEHKTTPFLDKKGEKIAHENLTAWDEGLTDNAFGTIDMDDEGMPTQRTLLIENGILKNF 344

Query: 307 LNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDK 366
           + DR  S        G GR QSYA+    RM NTYIAPG ++++++F  V+ G+Y     
Sbjct: 345 IADRTGSIRTGHPRTGSGRRQSYAYAAASRMRNTYIAPGNYSVDDIFNSVEKGIYCKQMG 404

Query: 367 GGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGF 426
           GG V  A G F F   E Y+++ G++ + ++   + G   + + +I    +DL +   GF
Sbjct: 405 GGSVG-ATGEFNFAVSEAYLVENGKLTKPLKGATLIGTATEIMNKISMSSQDLGLA-AGF 462

Query: 427 CGK-GQWVPVDDGGPHVLVKAI-VGGR 451
           CG     V V  G PH+ V  I VGGR
Sbjct: 463 CGSVSGSVYVTVGQPHIKVDGITVGGR 489


>pir||E70461 pmbA protein - Aquifex aeolicus >gi|2984159|gb|AAC07693.1|
           (AE000761) peptide maturation [Aquifex aeolicus]
           Length = 441
           
 Score =  144 bits (359), Expect = 2e-33
 Identities = 117/466 (25%), Positives = 224/466 (47%), Gaps = 44/466 (9%)

Query: 2   IDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN---GW 58
           +D L NL++KY       ++ FE     +  V N +VE V S+EE GIG+RVL +   G+
Sbjct: 1   MDNLENLVKKYIKPGYEYEVFFERVKKLKIEVSNEQVENVSSSEERGIGIRVLKDKRLGF 60

Query: 59  GFASTNDLSKLEDTIKMAIKLAKVSNA-EVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTK 117
            + S     +++DT++ A+++ ++    E   ++      KA+    ++ L + L+EK +
Sbjct: 61  SYTSFLGEEEIKDTVEKAMEMCEIQEPDEANGFIEKLKPSKAVSVYDEESLSIPLQEKME 120

Query: 118 LGLEVEKMIRR-DK----IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARS 172
           + +++EK  +  DK    ++ S  +  +F  R    NS G         + F     + +
Sbjct: 121 IPVKMEKYAKELDKRIVGVRKSTLTEVEFEVRSF--NSFG---------VEFGYRGTSYT 169

Query: 173 ADIMQTYWKSFGGTVGWEL-----VESVDFNYWANFISSKALSLLSARSPPSGEMPIIMD 227
           + I     ++    + WE      ++++++         K ++LL      +  MP++  
Sbjct: 170 SMIATLGTENDDSAISWEFRGARRLKNLNWKSMVEDAVFKTVNLLHPSPFETRSMPVVFF 229

Query: 228 PELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDD 287
            E   + + +A       D + +G+++L   + + + SE++T++DD ++   F ++ YD 
Sbjct: 230 RESFAMLL-DAFSPMFLGDYLVKGKTLLKDKVNEIVASEKITLVDDGSMEEGFSTFPYDA 288

Query: 288 EGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEW 347
           EG+P ++  +I  GV   +L+   T++  +  P G+    SY  +P    +N Y+  G  
Sbjct: 289 EGVPTRKNLLIDKGVFKGFLHSLYTARKSSQEPTGNSVRGSYKELPSSGTTNFYLEKGNL 348

Query: 348 TLEEM---FEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGN 404
           + EE+   ++EV   + ++G     VD  +G F  G   G + K+G+  + VR + ++GN
Sbjct: 349 SFEELLSYYDEVFLVLEVMGLH--TVDTISGDFSLGC-SGILYKKGKKDKTVRGITVAGN 405

Query: 405 ILDTLKEIKAVGRDLKIEFPGFCGKGQWVPVDDGGPHVLVKAIVGG 450
           ILD LK ++ VG DL      F G         G P VLVK +  G
Sbjct: 406 ILDLLKNVEEVGNDLT-----FYG-------SVGSPSVLVKKLTLG 439


>pir||B83330 hypothetical protein PA2529 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9948585|gb|AAG05917.1|AE004680_5
           (AE004680) hypothetical protein [Pseudomonas aeruginosa]
           Length = 477
           
 Score =  136 bits (340), Expect = 4e-31
 Identities = 125/456 (27%), Positives = 213/456 (46%), Gaps = 30/456 (6%)

Query: 1   MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW-G 59
           MID L++      +  +F  +R+        +V     E    +++ G  + V +NG   
Sbjct: 1   MIDPLKHRFAALRSRAEFHSLRYVQRSGEYLSVRRNVSEPPHFSQDRGAMLCVRLNGVEA 60

Query: 60  FASTNDLSK------LEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQ-KKDFLDVDL 112
           +A+TNDLS       LE   + A ++A+ +  +V      P  G++  +   +D     L
Sbjct: 61  YAATNDLSAAGLQAALEQAERQAERIARHALFDVRGLP--PASGRSQYRSPNQDAPFPSL 118

Query: 113 EEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTRK--IYLNSEGSVIETVVPRIYFSLSAVA 170
            E  +L  E    + RD+ +   +S    V+R+  +YLNS G+        +Y   S  A
Sbjct: 119 AECYELLAEESAKVPRDE-RLVNWSVFLEVSRQEQLYLNSAGAEQYHEQRFVYPGASVTA 177

Query: 171 RSADIMQTYWKSFGG-----TVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPII 225
                 QT  +SFGG       G E++E +     A  I+ +AL LL+A + PSG   ++
Sbjct: 178 YDGHDSQT--RSFGGHHAGQQGGAEVIERLGLVGAAPRIADQALQLLAAPNTPSGRCDLL 235

Query: 226 MDPELAGVFIHEALGHAVEADSVRQGESILSGM-------IGK-KIGSEELTVIDDPTLP 277
           + P+   + IHE++GH +E D +   E   +G         G+ + GS  L V  DP +P
Sbjct: 236 LMPDQMILQIHESIGHPLELDRILGDERNYAGTSFIKTEDFGRYQYGSSLLNVSFDPEIP 295

Query: 278 GKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRM 337
            +  SY  DD+G P ++  +I++G LL  L    +     L    + RA S+   P+ RM
Sbjct: 296 EELASYRQDDDGSPARKEYLIREGRLLRPLGGALSQHRSGLEGVANSRASSWNRAPIDRM 355

Query: 338 SNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVR 397
           +N  + PG+ +  ++   ++ GV M  ++   +D A   F FG + G +I++GE+K  V+
Sbjct: 356 ANLNLEPGDKSFAQLVAGIERGVLMSYNRSWSIDDARNKFQFGCEWGQLIEDGELKGVVK 415

Query: 398 DVGISGNILDTLKEIKAVGRDLKIEFPG--FCGKGQ 431
           +    G      + + AVG     E  G  +CGKG+
Sbjct: 416 NPNYRGISAQFWRNLSAVGDAGTFEVLGTPYCGKGE 451


>pir||E72342 pmbA-related protein - Thermotoga maritima (strain MSB8)
           >gi|4981252|gb|AAD35809.1|AE001743_11 (AE001743)
           pmbA-related protein [Thermotoga maritima]
           Length = 435
           
 Score =  133 bits (331), Expect = 4e-30
 Identities = 111/428 (25%), Positives = 206/428 (47%), Gaps = 28/428 (6%)

Query: 3   DELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFA 61
           D L  L +K   EV+   I F  T      + NG ++      +  + ++VL +G  G  
Sbjct: 8   DRLFALAKKNGVEVQ---ISFLETREFSLRLANGDLDQYTDAGKFNVEIKVLKDGKTGTF 64

Query: 62  STNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLD----VDLEEKTK 117
            T  L   E   + A+   +V ++E   Y     EG    ++ + ++     + ++EK  
Sbjct: 65  RTQVLENPEKCFEEALSNLQVKDSEEKEYF---FEGGKEYREMETYVGRFEKLSVKEKMD 121

Query: 118 LGLEVEKMIRRDK--IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADI 175
           +  +  +   +D+  +      Y D V +KI  N+ G  +E+ +   +    A+AR A+ 
Sbjct: 122 MAKKAHESAAKDERVVMVPTVMYKDMVIKKIITNTLGLDVESQMDGGFLFAMAIARDANP 181

Query: 176 MQTYWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFI 235
               W     T      E ++        + +A+SL+ +++ PSG+ P++M    A + +
Sbjct: 182 RSGSWYELARTP-----EDLNPEEIGKRAAEEAISLIGSKTIPSGKYPVLMR-NTALLDL 235

Query: 236 HEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRV 295
            E     + A++V++  S L G +G+++G+  +++ D P  P    S  +DDEG+P    
Sbjct: 236 MEMFIPMISAENVQKNLSPLKGKLGEQVGNPAVSIKDLPYHPKGLSSTPFDDEGVPTTEK 295

Query: 296 EIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEE 355
            ++++GVL  +L++ +T++   + P G+G       V  +R  N  + PGE + EE+ +E
Sbjct: 296 FVLENGVLKTFLHNLKTARKEGVEPTGNG------FVGGIRPVNLMLMPGEKSFEELLKE 349

Query: 356 VKFGVYMIGDKG--GQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIK 413
           +  GV +   +G     +  +G F   AK GY ++ GEI   V D+ ISGN LD L++I 
Sbjct: 350 MDRGVVITEVEGMHAGANSISGEFSLFAK-GYWVENGEIAHGVEDITISGNFLDLLRKIV 408

Query: 414 AVGRDLKI 421
            VG D+K+
Sbjct: 409 LVGNDVKV 416


>pir||D70703 tldD homolog Rv2315c - Mycobacterium tuberculosis (strain H37RV)
           >gi|1524285|emb|CAB02052.1| (Z79702) hypothetical
           protein Rv2315c [Mycobacterium tuberculosis]
           Length = 505
           
 Score =  125 bits (312), Expect = 7e-28
 Identities = 122/461 (26%), Positives = 203/461 (43%), Gaps = 35/461 (7%)

Query: 20  DIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSK--LEDTIKMA 76
           D+R          + +G++E    + E+G+ VRV++ G WGFAS  +L+      T + A
Sbjct: 36  DLRVHRISTEIIQLRDGELETAVISRELGLAVRVIVAGTWGFASHAELAPDVAAATARHA 95

Query: 77  IKLAKVS---NAEVPLYVGNPV--EGKAIIKQKKDFLDVDLEEKTKLGLEVE-KMIRRDK 130
           + +A V    N E       PV  + + +   + D   V   EK  +  +   +++  D 
Sbjct: 96  VHVATVLAALNTERVRLAPEPVYTDAEWVSNYRIDPFGVPASEKIAVLRDYSGRLLDADG 155

Query: 131 IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSA-----DIMQTYWKSFGG 185
           I     S +    +  Y ++ GS I     R+   L AVA  +     + M+T       
Sbjct: 156 IDHVSASLNAVKEQTFYADTFGSSITQQRVRLLPCLDAVAVDSAAGNFESMRTLAPPTAR 215

Query: 186 TVGWELVESVDFNYWANFISSKALSLLSARSPPS---GEMPIIMDPELAGVFIHEALGHA 242
             GWE+V   +   W + ++     L      PS   G   +++DP    + IHE++GHA
Sbjct: 216 --GWEVVAGDEIWNWTDELAQLPSLLAEKVRAPSVMPGPTDLVIDPTNLWLTIHESIGHA 273

Query: 243 VEADSVRQGESILSGM-------IGK-KIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKR 294
            E D     E+  +G        +G  + GS  + V  D T      +  YDDEG+  + 
Sbjct: 274 TEYDRAIGYEAAYAGTSFATPDKLGTLRYGSPVMNVTADRTAEFGLATVGYDDEGVAAQS 333

Query: 295 VEIIKDGVLLNYLNDRETSKALNLV-PNGHGRAQSYAHVPLVRMSNTYIAPG--EWTLEE 351
            ++++DGV + Y  DR  +  L     NG   A S  HVP+ RM+N  + PG  + +  +
Sbjct: 334 WDLVRDGVFVGYQLDRAFAPRLGEPRSNGCSYADSPHHVPIQRMANISLQPGIEDLSTAD 393

Query: 352 MFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKE 411
           +   V  G+Y++GDK   +D+   +F F  +  + I+ G++  Q+RDV    +  D    
Sbjct: 394 LIGRVDDGIYIVGDKSWSIDMQRYNFQFTGQRFFRIRGGQLYGQLRDVAYQSSTTDFWNA 453

Query: 412 IKAVGRDLKIEFPGF--CGK---GQWVPVDDGGPHVLVKAI 447
           ++AVG        G   CGK   GQ   V  G P  L + +
Sbjct: 454 MEAVGGPSTWRMGGAINCGKAQPGQVAAVSHGCPSALFRGV 494


>pir||T36780 hypothetical protein SCI28.10 - Streptomyces coelicolor  (fragment)
           >gi|5525068|emb|CAB50884.1| (AL096844) hypothetical
           protein [Streptomyces coelicolor A3(2)]
           Length = 435
           
 Score =  116 bits (287), Expect = 6e-25
 Identities = 110/405 (27%), Positives = 184/405 (45%), Gaps = 38/405 (9%)

Query: 20  DIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTIKMA-- 76
           D R E      + + + +  G     ++G  VRV+  G WGFAS  DL+ L+   K+A  
Sbjct: 34  DFRLERVRNASWRLRDARPAGSSDTTDLGYAVRVVHGGTWGFASGVDLT-LDAAAKVASQ 92

Query: 77  -IKLAKVSNAEVPLYVGN---------PVEG-KAIIKQKK--DFLDVDLEEKTKLGLEVE 123
            + +AK+S A+V    G+         PV   K+ I   +   F   D ++   L     
Sbjct: 93  AVAMAKLS-AQVIKAAGSDERVELAAEPVHADKSWISAYEIDPFSVPDADKAALLADWSA 151

Query: 124 KMIRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVA-----RSADIMQT 178
           +++  D +     S       K Y ++ G+V      R++  L+AV+        D M+T
Sbjct: 152 RLLAADGVDHVDASLLTVHENKFYADTAGTVTTQQRVRLHPVLTAVSVDDSSGEFDSMRT 211

Query: 179 YWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPP--SGEMPIIMDPELAGVFIH 236
                G   GWE +    +++ +       L     R+P   +G   +++DP    + IH
Sbjct: 212 LAPPAGR--GWEYLTGTGWDWDSELAEIPELLAEKMRAPSVEAGLYDLVVDPSNLWLTIH 269

Query: 237 EALGHAVEADSVRQGESILSG-------MIGK-KIGSEELTVIDDPTLPGKFGSYVYDDE 288
           E++GHA E D     E+  +G        +GK + GSE + V  D T      +  YDDE
Sbjct: 270 ESIGHATELDRALGYEAAYAGTSFATFDQLGKLRYGSELMNVTGDRTAEHGLATVGYDDE 329

Query: 289 GLPGKRVEIIKDGVLLNYLNDRETSKALNLV-PNGHGRAQSYAHVPLVRMSNTYIA--PG 345
           G+ G+  +++KDG L+ Y  DR  ++       NG   A S AHVP+ RM+N  +   PG
Sbjct: 330 GVEGQSWDLVKDGTLVGYQLDRRIARLTGFERSNGCAYADSPAHVPVQRMANVSLLPDPG 389

Query: 346 EWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEG 390
             + E++   V  G+Y++GD+   +D+   +F F  +  + I+ G
Sbjct: 390 GLSTEDLIGGVDRGIYVVGDRSWSIDMQRYNFQFTGQRFFRIENG 434


>gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis]
           Length = 448
           
 Score =  113 bits (280), Expect = 4e-24
 Identities = 106/407 (26%), Positives = 185/407 (45%), Gaps = 26/407 (6%)

Query: 20  DIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGWGFA-STNDLSK--LEDTIKMA 76
           D+ F      + +V  G++E V  +E   IG+R+ I     + S++D SK  L+  ++ A
Sbjct: 27  DVVFVQGQSQDISVRLGQLEDVGRSEGAEIGLRLFIGHRSASVSSSDFSKEALDALVERA 86

Query: 77  IKLAKVSNAEVPLYVGNP-----VEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKI 131
           + +A+   A    + G       ++G A   +  D  ++      +L L+ E   R    
Sbjct: 87  VAMAR--EAPEDRWAGLAPKELLMQGTAPEIESDDGKEIAPAVLRELALKAEDAARSVDG 144

Query: 132 KTSRFSYSDFVTRKIYL--NSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGW 189
            T+    S    R I+    SEG    +       S   +A     MQ  +  F  T  +
Sbjct: 145 ITNSEGASASAGRTIFALATSEGFTRGSSSSSYGCSACVIAGQGVNMQRDY-DFHATRYF 203

Query: 190 ELVESVDFNYWANFISSKALSLLSARSPP----SGEMPIIMDPELAGVFIHEALGHAVEA 245
           E +++      A  I ++A     AR  P    SG+MPII DP +   F+   +   +  
Sbjct: 204 EDLDA------AELIGTRAAERTIARLNPTRIDSGQMPIIFDPRVGSGFLSYLI-QGISG 256

Query: 246 DSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLN 305
            ++ +  S L   +GK + +E +T+ +DP       S  +D EGLP K   II  G L  
Sbjct: 257 GAITRKTSFLLDSLGKPVFNEGITIKEDPWRKRGIASRAFDGEGLPTKPNNIIDKGRLNG 316

Query: 306 YLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGD 365
           +L D   ++ L + P GH R +     P    +N Y+  G+ T EE+  ++K G+Y+   
Sbjct: 317 WLLDSAAARQLGMTPTGHAR-RGVGGPPSTGTANLYLEAGKVTPEELMSDIKLGIYVTEM 375

Query: 366 KGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEI 412
            G  V++  G +  GA  G+II++G++ E V ++ ++GN+ D   ++
Sbjct: 376 IGSGVNMITGDYSRGA-SGFIIRDGQLAEPVAEITVAGNLKDIFMQM 421


>pir||B71249 hypothetical protein PH0249 - Pyrococcus horikoshii
           >gi|3256638|dbj|BAA29321.1| (AP000001) 426aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 426
           
 Score =  111 bits (276), Expect = 1e-23
 Identities = 120/436 (27%), Positives = 198/436 (44%), Gaps = 54/436 (12%)

Query: 9   IEKYSNEVKFMDIRFENTIYTEFT---------VENGKVEGVESNEEVGIGVRVLING-- 57
           +EK    +K  D+ +E  IY E           +   ++E        GIG+R+L+ G  
Sbjct: 6   VEKLVKILKSFDVEWE--IYWESASSLSLKFRKIRRAEIERSTYRVSSGIGLRILVGGKI 63

Query: 58  -WGFASTNDLSK--LEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQ---KKDFLDVD 111
            + + S +D SK  LE  +K A+K+AK+S  E P +   PV GK    +    K  +D+ 
Sbjct: 64  GFSYLSGSDFSKDELELLVKRALKIAKISGTEYPAF---PVPGKYPSIRGLYDKRIVDLS 120

Query: 112 LEEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTR---KIYLNSEGSVIETVVPRIYFSLSA 168
           +E+ +  G E+        +    F  +   T    +  +NS G  +E    R   +L  
Sbjct: 121 IEDLSYYGTEL--------VNIEVFGEASIGTSTGIRGIMNSNG--VEGSENRSLLTLGL 170

Query: 169 VA-RSADIMQTYWKSFGGTVGWE-LVESVDFNYWANFISSKALSLLSARSPPSGEMPIIM 226
            A        +Y KSF      E +VE +       F  S+      A+     E  II+
Sbjct: 171 YAYEKGKGSGSYGKSFRVLPDMEKVVEEIKETAMFEFKLSR-----EAKKIEKYEGEIII 225

Query: 227 DPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYD 286
           +P+    F+   + + V A SV    S     +G ++ SE  ++IDDPT+    GSY +D
Sbjct: 226 EPKALISFLSIFVPN-VSAKSVYMKRSRFE-RLGVEVSSESFSIIDDPTIDEGLGSYSFD 283

Query: 287 DEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGE 346
            EG PG R  IIKDGVL ++L+D++    L +   G+   +SY+  P++  SN  I  G 
Sbjct: 284 GEGNPGMRKFIIKDGVLTSFLSDQKYGSLLGIGSTGNA-IRSYSSQPIIDSSNLLIPSGN 342

Query: 347 WTLEEMFEEVKFGVYMIGDKGGQ-VDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNI 405
            TL+E       G+++    G    +   G F    + GYI+    +K    ++ I GNI
Sbjct: 343 ETLDE-------GIFIRSVYGEHTANPITGDFSLNIELGYIVNNRGVKPFKGNM-IVGNI 394

Query: 406 LDTLKEIKAVGRDLKI 421
            + LK + ++ ++++I
Sbjct: 395 FEMLKNVTSIDKNVEI 410


>pir||B69009 conserved hypothetical protein MTH1070 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622168|gb|AAB85559.1| (AE000877) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 430
           
 Score =  110 bits (273), Expect = 3e-23
 Identities = 96/414 (23%), Positives = 190/414 (45%), Gaps = 33/414 (7%)

Query: 8   LIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDL 66
           + E Y    K +++  +  +     ++ GK+E +      GIG+R+L  G  GFA T+D 
Sbjct: 18  MAEVYIEREKTLEVEIQRDL-----IDFGKIESM-----TGIGIRILKEGRMGFAYTSDP 67

Query: 67  SKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIK-QKKDFLDVDLEEKTKLGLEVEKM 125
             ++  ++MA +  ++++ +       P    ++     + F D+++E+  ++   +   
Sbjct: 68  DGVDVAVRMAAQNLQLADPDENFGFSEPSTYPSVKGIHDRSFDDLEVEDSVEMAGRMINR 127

Query: 126 IRRDKIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGG 185
           +  +  K +   ++        LNSEG         +  S S+   SA I  T  ++   
Sbjct: 128 VLEEGCKPTSGGFTASRIETFILNSEG---------VEESSSSTGFSAHISVTAGENGMK 178

Query: 186 TVGWELVESVDFNYWANFISSKALSL----LSARSPPSGEMPIIMDPELAGVFIHEALGH 241
           T  +E   S   +    +++ +A  +    +  RS  SG +P ++D   A   +    G 
Sbjct: 179 TTAYESDSSCKLDINPEWVAGRACRIARDSMGGRSIESGRIPAVLDYHAAAGLLGTFAG- 237

Query: 242 AVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDG 301
           A  AD+V++G S+L+  IG ++  E L+V DD TL G  GS  +D EG P +R  +++DG
Sbjct: 238 AFSADNVQRGRSVLADRIGSQVTGEGLSVYDDGTLEGGLGSAPFDGEGTPSQRTALVEDG 297

Query: 302 VLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVY 361
           +L  Y+++  T+        G+G  + Y  VP V  +N  +   E+      ++ + G++
Sbjct: 298 ILRGYMHNIYTASKGRADSTGNG-LRGYMEVPAVSTTNFIL---EFDSTVPLDDFR-GIF 352

Query: 362 MIGDKGGQ-VDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKA 414
           +    G    +  +G F   A   ++   GE    V+   +SGNI + + ++ +
Sbjct: 353 VTDVLGAHTANPISGDFSVEANNAFMADSGEF-TPVKKAMLSGNIFELMMKVSS 405


>sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||S13730 pmbA protein -
           Escherichia coli >gi|42440|emb|CAA38091.1| (X54152) pmbA
           is involved in the  production of antibiotic MccB17
           [Escherichia coli] >gi|537077|gb|AAA97132.1| (U14003)
           pmbA gene product [Escherichia coli]
           >gi|1732440|dbj|BAA07915.1| (D44452) TldE protein
           [Escherichia coli] >gi|1790682|gb|AAC77192.1| (AE000494)
           maturation of antibiotic MccB17, see tld genes
           [Escherichia coli K12]
           Length = 450
           
 Score =  102 bits (253), Expect = 6e-21
 Identities = 110/430 (25%), Positives = 192/430 (44%), Gaps = 27/430 (6%)

Query: 9   IEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLI-NGWGFASTNDLS 67
           +E  S +    ++    T     +   G+VE VE N +  +G+ V   N  G AS+ DLS
Sbjct: 26  LELASGKSDGAEVAVSKTTGISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLS 85

Query: 68  K--LEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFL---DVDLEEKTKLGLEV 122
              +  T++ A+ +A+ ++ +    V +  E  A      D     +V  +E  +L    
Sbjct: 86  PQAIARTVQAALDIARYTSPDPCAGVADK-ELLAFDAPDLDLFHPAEVSPDEAIELAARA 144

Query: 123 EKM-IRRDK--IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTY 179
           E+  ++ DK    T   S++     K++ NS G +      R   S   +A     M+  
Sbjct: 145 EQAALQADKRITNTEGGSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDME-- 202

Query: 180 WKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELA-GVFIHEA 238
            + +  T+G  + +     +     + + LS LS R   + + P+I   E+A G+F H  
Sbjct: 203 -RDYAYTIGRAMSDLQTPEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGH-- 259

Query: 239 LGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298
           L  A+   SV +  + L   +GK+I  + LT+ + P L     S  +D EG+  +R +II
Sbjct: 260 LVGAIAGGSVYRKSTFLLDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDII 319

Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358
           KDG+L  +L    +++ L L   GH             + N  IA    + E+M +E+  
Sbjct: 320 KDGILTQWLLTSYSARKLGLKSTGHAGG----------IHNWRIAGQGLSFEQMLKEMGT 369

Query: 359 GVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418
           G+ +    G  V    G +  GA  G+ ++ GEI+  V ++ I+GN+ D  + I  VG D
Sbjct: 370 GLVVTELMGQGVSAITGDYSRGA-AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGND 428

Query: 419 LKIEFPGFCG 428
           ++      CG
Sbjct: 429 IETRSNIQCG 438


>pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus abyssi  (strain
           Orsay) >gi|5457662|emb|CAB49153.1| (AJ248283) PMBA
           PROTEIN (TLDE PROTEIN) [Pyrococcus abyssi]
           Length = 427
           
 Score =  100 bits (247), Expect = 3e-20
 Identities = 112/400 (28%), Positives = 190/400 (47%), Gaps = 43/400 (10%)

Query: 37  KVEGVESNEEV--GIGVRVLING---WGFASTNDLSK--LEDTIKMAIKLAKVSNAEVPL 89
           KVE    + EV  GIG+RVL  G   + + S ++ ++  LE  +K A K+AKV+ +   +
Sbjct: 40  KVEVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGS---I 96

Query: 90  YVGNPVEGK-----AIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTR 144
           Y G PV  K      +   K    ++  EE  + G E+      D    +  S     + 
Sbjct: 97  YPGFPVPKKFPNVRGLYDDK--IRNLSTEEIVEYGTELV-----DVPPNAEASIGLSTSE 149

Query: 145 KIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWEL-VESV-DFNYWAN 202
           +  +NS G+        + F L    +S     +Y KSF      E  +E V +   W  
Sbjct: 150 RGIMNSNGTEGREERTLLAFGLYVFEKSKGT-GSYSKSFRRLPKLESEIEGVREKALWEF 208

Query: 203 FISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKK 262
            +SSKA  L       +GE  II++P+     +   L + V A +V    S  + + G +
Sbjct: 209 EMSSKARKL----EKYNGE--IILEPKAVASILSIFLPN-VSARNVYLKRSRFTEL-GIE 260

Query: 263 IGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNG 322
           + S  LT+IDDPT+ G   SY +D EG PG R  IIK+G+L ++L D++    + +   G
Sbjct: 261 VASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTG 320

Query: 323 HGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQ-VDIANGSFMFGA 381
           +  ++ Y+  P +  SN  I+PG        +E   G+++ G  G    +  +G F    
Sbjct: 321 NA-SRGYSSQPSISPSNIMISPGN-------DEQDEGIFIRGIYGEHTANSVSGDFSLNV 372

Query: 382 KEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKI 421
             GY+++ GEI+    ++ + GN+ + LK +  +G++++I
Sbjct: 373 DLGYVVRGGEIRPFKGNM-LVGNVFEMLKNVTNIGKEIEI 411


>pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (strain PCC 6803)
           >gi|1652621|dbj|BAA17541.1| (D90907) PmbA protein
           [Synechocystis sp.]
           Length = 427
           
 Score = 99.1 bits (243), Expect = 9e-20
 Identities = 97/394 (24%), Positives = 180/394 (45%), Gaps = 31/394 (7%)

Query: 34  ENGKVEGVESNEEVGIGVRVLINGW-GFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVG 92
           E  +++ +ES+E  G+ +R+  NG  G A      + E  ++ A+ LA ++    P +  
Sbjct: 35  EANRLKQLESSESEGVALRLWKNGQAGLAVAYGPVEPEILVEKALALAALNPPNPPRFTA 94

Query: 93  NPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIK---TSRFSYSDFVTRKIYLN 149
              + +  + +     DV +E+    G      +R +  +   +   + S   TR I  N
Sbjct: 95  PRQDYRESLGE-----DVSVEQLIDWGQTAIASLRSEFAEVLCSGELACSTDSTRLI--N 147

Query: 150 SEGSVIETVVPRI--YFSLSAVARSADIMQTY--WKSFGGTVGWELVESVDFNYWANFIS 205
           SEG         +  YF +  + R  D +  Y   +  G T   ++VE+         + 
Sbjct: 148 SEGLDCTWTERSLSYYFGVEWI-RGEDFLAIYDGEQCRGQTNVGQVVEN---------LR 197

Query: 206 SKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGS 265
            + L +   +    G+MPI++    A + + + +G A+    V +  S  +  +G+ +  
Sbjct: 198 QRLLWVEVNQQIQGGKMPILLTSGAASL-LWDTVGEALHGQRVAEDSSPWAEKLGQTVAI 256

Query: 266 EELTVIDDPT-LPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHG 324
           EEL +  DPT +P       +DDEG   +++ +IK+G +  +  D ET++ L     G+G
Sbjct: 257 EELNISQDPTAIPF---DCPFDDEGSRTQKLALIKNGKIAQFYTDHETAEKLGTTTTGNG 313

Query: 325 RAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEG 384
              S    P   + N  I PG  + +++ +++  G+ +    GG  DI +G F      G
Sbjct: 314 FRPSLGSAPQPGLVNMLITPGTASFDQLLKKLGNGLVVDQILGGGADI-SGDFSINVDLG 372

Query: 385 YIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418
           Y ++ GEI  +V+D  +SGNI + L +I A+G D
Sbjct: 373 YRVQNGEITGRVKDTMVSGNIYELLNQIIALGSD 406


>pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9657118|gb|AAF95676.1| (AE004322) pmbA
           protein [Vibrio cholerae]
           Length = 447
           
 Score = 96.7 bits (237), Expect = 5e-19
 Identities = 102/401 (25%), Positives = 183/401 (45%), Gaps = 40/401 (9%)

Query: 37  KVEGVESNEEVGIGVRVLINGW-GFASTNDLSK--LEDTIKMAIKLAKVSNAEVPLYVGN 93
           +VE VE N +  +G+ V      G AST+DLS+  +  T+  A+ +A+ ++A+   Y G 
Sbjct: 50  EVENVEFNSDGALGITVYRGQRKGSASTSDLSEKAIRQTVLAALDIAQYTSADP--YAG- 106

Query: 94  PVEGKAIIKQKKDFLDV--------DLEEKTKLGLEVEKMIRRDKIKTSRF-SYSDFVTR 144
           P   + ++++  D LD+        D+  +  +  E   +    KIK S   SY      
Sbjct: 107 PAPKELMVQEIPD-LDLFHPDEPNPDVAAQIAIAAERAALGYSKKIKQSDGGSYDSHYGV 165

Query: 145 KIYLNSEGSVIETVVPRIYFSLSAVA--RSADIMQTYWKSFGGTVG--WELVESVDFNYW 200
           ++Y NS G +      R   S S +   R+ ++ + Y  +        W   ESV     
Sbjct: 166 RVYGNSHGLLASYASSRHSISCSVIGEGRNGEMERDYSYTVARHRDDLWT-PESVGLQAA 224

Query: 201 ANFISSKALSLLSARSPPSGEMPIIMDPELA-GVFIHEALGHAVEADSVRQGESILSGMI 259
            N +S      L  +   +G+ P++   ++A G+  H  +  A+   ++ +  S L   +
Sbjct: 225 ENTVSR-----LDPQKLKTGQFPVMFAADVATGLIGHLVM--AISGGNLYRKSSFLLDHL 277

Query: 260 GKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLV 319
           GK I      + + P +     S  +D EG+  + +EII DGVL  YL     ++ +N+ 
Sbjct: 278 GKTILPTWFNISERPHVMRGLASSPFDSEGVRTQDLEIITDGVLATYLLTSYAARKMNMT 337

Query: 320 PNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMF 379
           P GH             + N Y+       ++M +E+  G+ +    G  V++  G +  
Sbjct: 338 PTGHAGG----------IHNWYVKSTGQNYQQMLKELGTGLLVTEVMGQGVNVVTGDYSR 387

Query: 380 GAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420
           GA  G+ ++ GEIK  V ++ I+GN+   L++I AVG D++
Sbjct: 388 GA-AGFWVENGEIKYPVSEITIAGNLKQMLQQIVAVGSDIE 427


>sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C64186 pmbA protein -
           Haemophilus influenzae (strain Rd KW20)
           >gi|1574709|gb|AAC22807.1| (U32795) pmbA protein (pmbA)
           [Haemophilus influenzae Rd]
           Length = 451
           
 Score = 96.3 bits (236), Expect = 6e-19
 Identities = 94/393 (23%), Positives = 190/393 (47%), Gaps = 24/393 (6%)

Query: 37  KVEGVESNEEVGIGVRVLINGW-GFASTNDLSK--LEDTIKMAIKLAKVSNAE--VPLYV 91
           ++E VE   +  +G+ V +    G AST+DLS+  +++ ++ A+ +AK ++ +    L  
Sbjct: 54  EIENVEFTNDGALGISVYMGQQKGNASTSDLSESAIKNAVEAALAIAKYTSPDDCTGLAD 113

Query: 92  GNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKM-IRRDK--IKTSRFSYSDFVTRKIYL 148
            + +   A   +     D+D+++ T+L L+ E+  ++ D+  I ++  S++     K+Y 
Sbjct: 114 KDLMAFDAPDLELYHAADIDVDKATELALQAEQAALQADERIINSNGASFNSHTGVKVYG 173

Query: 149 NSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVESVDFNYWANFISSKA 208
           NS G +   +  R   S S +    D ++  ++    T+  E  +     +     + K 
Sbjct: 174 NSHGMLQSYLSSRYSLSCSVIGGVEDALENDYEY---TISREFDKLQSPIWVGENCAKKV 230

Query: 209 LSLLSARSPPSGEMPIIMDPELA-GVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEE 267
           +S L+ +   + E+P+I   ++A G+  H A   A+   S+ +  S L   +GK++  + 
Sbjct: 231 VSRLNPQKLSTREVPVIFLNDVATGIISHFAA--AISGGSLYRKSSFLLDHLGKQVLPDW 288

Query: 268 LTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQ 327
            ++ + P L  +  S  +D EG+  +  EI+++G+L  YL    + K L +   GH    
Sbjct: 289 FSISERPHLLRRLASTPFDSEGVRTQDREIVENGILQTYLVTSYSGKKLGMSSTGHAGG- 347

Query: 328 SYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYII 387
              H  LV+ + T        L  +  ++  G+ +    G  V+I  G +  GA  G+ +
Sbjct: 348 --IHNWLVKPNLT------GGLTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGA-SGFWV 398

Query: 388 KEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420
           + GEI+  V ++ I+G + D LK + AV  D++
Sbjct: 399 ENGEIQYPVAEITIAGQLQDMLKNMLAVADDIE 431


>pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aeruginosa  (strain
           PAO1) >gi|9950709|gb|AAG07860.1|AE004861_1 (AE004861)
           PmbA protein [Pseudomonas aeruginosa]
           Length = 449
           
 Score = 94.0 bits (230), Expect = 3e-18
 Identities = 95/406 (23%), Positives = 180/406 (43%), Gaps = 41/406 (10%)

Query: 32  TVENGKVEGVESNEEVGIGVRVLIN---GWGFASTNDLSKLEDTIKMAIKLAKVSNAEVP 88
           +V  G+VE VE N + G G+ +      G    S    + + +T+  A+ +A+ ++ +  
Sbjct: 48  SVRQGEVETVEFNRDQGFGITLYAGQRKGSASTSATGEAAIRETVAAALAIARHTSEDEC 107

Query: 89  LYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTR---- 144
             + +           ++  ++DL     L  E + + R    + + F+    VT+    
Sbjct: 108 AGLADAA------LMARELPELDLYHPWSLSPE-QAVERALACEAAAFAADKRVTKADGT 160

Query: 145 --------KIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT-YWKSFGGTVGWELVESV 195
                   ++Y NS G +      R   S   +A     MQ  YW       G  L  + 
Sbjct: 161 TLNTHQGCRVYGNSHGFIGGYASTRHSLSCVMIAEGEGQMQRDYWYDVNRR-GEALASAE 219

Query: 196 DFNYWANFISSKALSLLSARSPPSGEMPIIMDPELA-GVFIHEALGHAVEADSVRQGESI 254
                A   + +A S L AR   + E+P++  PE+A G+F H  LG A+   S+ +  S 
Sbjct: 220 SIGRRA---AERAASRLGARPVQTAEVPVLFAPEIAVGLFGH-FLG-AISGGSLYRKSSF 274

Query: 255 LSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSK 314
           L G +G+++  E L++ + P L G  GS  +D +GL       +++G L++Y+    + +
Sbjct: 275 LEGALGQRLFPEWLSIDERPHLVGALGSASFDSDGLATYAKPFVENGELVSYVLGTYSGR 334

Query: 315 ALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIAN 374
            L L    +             + N +++ G+     +   ++ G+ +    G  V++  
Sbjct: 335 KLGLPSTANAGG----------VHNLFVSHGDEDQAALIRRMERGLLVTELMGQGVNLVT 384

Query: 375 GSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLK 420
           G +  GA  GY ++ GEI+  V++V I+ N+ D  + I AVG+D++
Sbjct: 385 GDYSRGAA-GYWVENGEIQFPVQEVTIAANLRDLFRRIVAVGKDIE 429


>sp|P57191|PMBA_BUCAI PMBA PROTEIN HOMOLOG >gi|10038774|dbj|BAB12809.1| (AP001118) pmbA
           protein [Buchnera sp. APS]
           Length = 446
           
 Score = 92.8 bits (227), Expect = 7e-18
 Identities = 97/429 (22%), Positives = 197/429 (45%), Gaps = 27/429 (6%)

Query: 1   MIDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLIN-GWG 59
           +++ ++N ++   N    +++  + TI     V N  VE VE N + G+ + V      G
Sbjct: 14  LVNTVKNTLKLSKNINASVEVFIKKTIGISVNVRNNVVENVEFNSDGGLFITVYNKFSKG 73

Query: 60  FASTNDLS--KLEDTIKMAIKLAKVSNAEVPLYVGNP-VEGKAIIKQKKDFL---DVDLE 113
             S+ D S   +++ + +AI ++K S+++   + G P ++       + D     + ++E
Sbjct: 74  SVSSKDFSIKNIKNMLDIAINISKYSSSD--FFSGLPDIKFLCFHSMELDLFHPWEFNIE 131

Query: 114 EKTKLGLEVEKM-IRRDK-IKTSRFSY-SDFVTRKIYLNSEGSVIETVVPRIYFSLSAVA 170
              K+ +  EK     DK I  S  S+ +   T  ++ NS G + +    R       +A
Sbjct: 132 NAIKMSILSEKSAFESDKRIVNSEGSFLNSHTTINVFGNSLGVLEKYKSTRYSNYTCMIA 191

Query: 171 RSADIMQTYWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPEL 230
           +  + MQ   + F  ++   + + +         + +A+S L +R   +   PII   E+
Sbjct: 192 KDKNSMQ---RDFDYSLSRRIDDLIKPEILGQKTAKRAISRLGSRKIQTMRSPIIFSSEI 248

Query: 231 AGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGL 290
           + +F    L  A+  D+V Q  + L   +  KI  + L + ++P L    GS  +D+EG+
Sbjct: 249 SHMFFSH-LASAISGDNVYQKSTFLINDLKMKIFPDWLDIEENPHLKRGLGSKPFDNEGV 307

Query: 291 PGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLE 350
             +   IIK G+L  +L +   ++ L L   G+             + N  ++    + E
Sbjct: 308 ATEIKYIIKAGILQTWLLNCYNARKLKLDSTGNCGG----------IHNWLVSNQNISFE 357

Query: 351 EMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLK 410
           E+ +++  G+ +    G  VDI NG++  GA  G+ +++G+I   + ++ ISGN+ +   
Sbjct: 358 ELLKKMDQGILVTELMGQGVDIINGNYSRGA-VGFWVEKGKISYPINEITISGNLRNMWN 416

Query: 411 EIKAVGRDL 419
            I ++  D+
Sbjct: 417 NIVSISSDV 425


>pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii
           >gi|3257260|dbj|BAA29943.1| (AP000003) 443aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 443
           
 Score = 89.3 bits (218), Expect = 8e-17
 Identities = 64/212 (30%), Positives = 114/212 (53%), Gaps = 17/212 (8%)

Query: 214 ARSP---PSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTV 270
           AR+P   P G   +I DP LA   +   +G A  A +V  G S  +  + +K+ SE +T+
Sbjct: 212 ARNPEQGPEGRFDVIFDP-LAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEIVTI 270

Query: 271 IDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYA 330
            D   LP  + +  +DDEG+P K   +I  G+L  YL +   +K        +GR ++ A
Sbjct: 271 KDVGNLPNGYATRKFDDEGVPTKETILIHKGILKTYLFNTSLAKK-------YGR-ETTA 322

Query: 331 HVPLV--RMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV-DIANGSFMFGAKEG-YI 386
           +  L+  R  N  + PG++T +E+F+EVK G+Y+      +  +   G F    ++G ++
Sbjct: 323 NAGLIAPRAWNIVLEPGDYTKDELFQEVKKGIYITNVWYTRFQNYMTGDFSTIPRDGIFL 382

Query: 387 IKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418
           I+ GE+K  +R++ +S N+L  L+ + A+ ++
Sbjct: 383 IENGELK-PIRNIRVSDNMLRILQNVVALSKE 413


>pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (strain Orsay)
           >gi|5458676|emb|CAB50163.1| (AJ248287) hypothetical
           protein [Pyrococcus abyssi]
           Length = 443
           
 Score = 87.8 bits (214), Expect = 2e-16
 Identities = 63/212 (29%), Positives = 115/212 (53%), Gaps = 17/212 (8%)

Query: 214 ARSP---PSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTV 270
           AR+P   P G+  +I DP LA   +   +G A  A +V  G S  +  + +K+ SE +T+
Sbjct: 212 ARNPEQGPEGKFDVIFDP-LAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEVVTI 270

Query: 271 IDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYA 330
            D   LP  +G+  +DDEG+P +   +I+ G L  YL +   +K        +G+ ++ A
Sbjct: 271 KDIGNLPNGYGTRKFDDEGVPTRETVLIERGTLKTYLFNTSLAKK-------YGK-ETTA 322

Query: 331 HVPLV--RMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV-DIANGSFMFGAKEG-YI 386
           +  L+  R  N  + PG++T +E+F+EVK G+Y+      +  +   G F    ++G ++
Sbjct: 323 NAGLISPRAWNIVLEPGDYTKDELFQEVKRGIYITNVWYTRFQNYMTGDFSTIPRDGIFL 382

Query: 387 IKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418
           I+ GE+K  +R++ +S N+L  L+ I  + ++
Sbjct: 383 IENGELK-PIRNIRVSDNMLRILQNIVGLTKE 413


>pir||D81151 pmbA protein NMB0839 [imported] - Neisseria meningitidis  (group B
           strain MD58) >gi|7226074|gb|AAF41250.1| (AE002437) pmbA
           protein [Neisseria meningitidis MC58]
           Length = 443
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 92/413 (22%), Positives = 179/413 (43%), Gaps = 41/413 (9%)

Query: 23  FENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW-GFASTNDLSK--LEDTIKMAIKL 79
           F  ++    +V  G++E +E  ++  + + V +    G AST D S+  L+DT+K AI +
Sbjct: 33  FSESLGQSVSVRLGEIEQIEFQQDKSLDITVYVGKRKGRASTADFSEKALQDTVKAAIDI 92

Query: 80  AKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL----------EVEKMIRRD 129
           A+ +  +    + +       I     + + DL+ +  +GL          E E++   +
Sbjct: 93  ARHTAEDGCAGLADACLMAKHIGDPDLYHEWDLDTEAAVGLAKQCEQAALNEDERIENSE 152

Query: 130 --KIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT-YW-KSFGG 185
              ++T  + Y       +Y N+ G            S S VA   + MQ  YW  S   
Sbjct: 153 GAAVQTGHYQY-------VYGNTHGFAAHRQGTHHSISCSVVAADENGMQRDYWYDSACR 205

Query: 186 TVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEA 245
               +  E++         + + L  L +RS P+G  P++ D  ++G  I   +G A+  
Sbjct: 206 HPDMDSPETI-----GQTAARRTLRRLGSRSIPTGSYPVLFDTTVSGGLIGHLVG-ALSG 259

Query: 246 DSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLN 305
            ++ +  S L   IGKK+  + L + ++P +P  F S  +D EG+      +I++G++  
Sbjct: 260 GALYRQSSFLIDSIGKKVLPDFLNLREEPHIPRSFRSSYFDAEGVATAPRFVIQNGIVEG 319

Query: 306 YLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGD 365
           Y     +++ L +   G+      AH       N Y+     T  ++ +E+  G+ +   
Sbjct: 320 YFLSSYSARKLGMQTTGNAGG---AH-------NLYLNHTHETQSDLLKEMGTGLLVTEL 369

Query: 366 KGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418
            G   +   G +  GA  G+ ++ G I   V ++ ++G + D  ++I  V  D
Sbjct: 370 MGQGANTITGDYSRGA-AGFWVENGVIAYPVHEITVAGRLQDMYRDIVGVADD 421


>pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii
           >gi|3257987|dbj|BAA30670.1| (AP000006) 445aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 445
           
 Score = 83.5 bits (203), Expect = 5e-15
 Identities = 52/199 (26%), Positives = 97/199 (48%), Gaps = 2/199 (1%)

Query: 221 EMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKF 280
           E P+I  P       H AL  A   + + +  + L+  +G+KI S+ +T+ DD       
Sbjct: 222 EAPVIFSPWAISGLFHYALFPAFSGERLIKKTTPLADKVGEKIASDVITIYDDTFHELSV 281

Query: 281 GSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNT 340
              + D EG+P ++  +I++GV   ++ D   +K       GHG+         + +++ 
Sbjct: 282 VKAIADGEGVPTRKTMLIENGVFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVTIGLNSA 341

Query: 341 YIAPGEWTLEEMFEEVKFGVYMIGDKGG-QVDIANGSFMFGAKEGYIIKEGEIKEQVRDV 399
            I  G+ +LEEM +++K G  + G +G    +  NG+F   A   Y+I++GEI      +
Sbjct: 342 VIENGKRSLEEMIQDIKHGYLVEGVQGAHSSNPDNGNFAISANPAYLIEDGEIAGSTVFL 401

Query: 400 GISGNILDTLKEIKAVGRD 418
            ++ NI + LK+   V ++
Sbjct: 402 -VASNIYELLKQASEVSKE 419


>pir||H81869 hypothetical protein NMA1048 [imported] - Neisseria meningitidis
           (group A strain Z2491) >gi|7379746|emb|CAB84314.1|
           (AL162755) hypothetical protein NMA1048 [Neisseria
           meningitidis Z2491]
           Length = 443
           
 Score = 80.8 bits (196), Expect = 3e-14
 Identities = 90/413 (21%), Positives = 177/413 (42%), Gaps = 41/413 (9%)

Query: 23  FENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW-GFASTNDLSK--LEDTIKMAIKL 79
           F  ++    +V  G++E +E  ++  + + V +    G A T D S+  L DT++ A  +
Sbjct: 33  FSESLGQSVSVRLGEIEQIEFQQDKSLDITVYVGKRKGRAGTADFSEQALRDTVRAAADI 92

Query: 80  AKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGL----------EVEKMIRRD 129
           A+ +  +    + +P      I     + + DL+ +  +GL          E E++   +
Sbjct: 93  ARHTAEDGCAGLADPELMAQHIGDPDLYHEWDLDTEAAVGLAKQCEQAALNEDERIENSE 152

Query: 130 --KIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQT-YW-KSFGG 185
              ++T  + Y       +Y N+ G            S S VA   + MQ  YW  S   
Sbjct: 153 GAAVQTGHYQY-------VYGNTYGFAAHRQSTHHSISCSVVAADENGMQRDYWYDSACR 205

Query: 186 TVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEA 245
               +  E++         + + L  L +RS P+G  P++ D  ++G  I   +G A+  
Sbjct: 206 HPDMDSPETI-----GQTAARRTLRRLGSRSIPTGNYPVLFDTTVSGGLIGHLVG-ALSG 259

Query: 246 DSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLN 305
            ++ +  S L   IGKK+  + L + ++P +P  F S  +D EG+      +I++G++  
Sbjct: 260 GALYRQSSFLIDSIGKKVLPDFLNLREEPHIPRSFRSSYFDAEGVATAPRFVIQNGIVEG 319

Query: 306 YLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGD 365
           Y     +++ L +   G+      AH       N Y+     T  ++ +E+  G+ +   
Sbjct: 320 YFLSSYSARKLGMQTTGNAGG---AH-------NLYLNHTHETQSDLLKEMGTGLLVTEL 369

Query: 366 KGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRD 418
            G   +   G +  GA  G+ ++ G I   V ++ ++G + D  ++I  V  D
Sbjct: 370 MGQGANTITGDYSRGA-AGFWVENGVIAYPVHEITVAGRLQDMYRDIVGVADD 421


>pir||S75708 hypothetical protein sll0887 - Synechocystis sp. (strain PCC 6803)
           >gi|1001203|dbj|BAA10443.1| (D64003) hypothetical
           protein [Synechocystis sp.]
           Length = 446
           
 Score = 80.4 bits (195), Expect = 4e-14
 Identities = 95/411 (23%), Positives = 178/411 (43%), Gaps = 30/411 (7%)

Query: 33  VENGKVEGVESNEEVGIGVRVLINGWGFASTNDLSKLEDTIKMAIKLAKVSNAEVPLY-- 90
           V++G+ + VE++    + VRV    W       ++   D  +  I LA  + AE   +  
Sbjct: 37  VDSGEPKQVEASNRASVIVRV----WNEKGLVGVTSTTDLDQAGISLALETAAEASAFGI 92

Query: 91  VGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTSRF---------SYSDF 141
             N  +     +      + D+ E   +G  +  +++ ++   +             S+ 
Sbjct: 93  TDNIPDFSPEAQVPIGGAENDVAEPAPMGDLITTLVKAEQDLLASHPAITGVPYNGLSEQ 152

Query: 142 VTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWELVESVDFNYWA 201
            T + YLNS G+  +    R Y S+   +R+    +    +    +  +L  S+D +   
Sbjct: 153 TTERFYLNSAGA--KRYECRSYASIYLYSRAEQEGKKPRSAGEMKISRDLA-SLDIDGCL 209

Query: 202 NFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSG-MIG 260
             +  K LS L  R  P+G+  ++     A + +  A  +   A S+   +S+ +   +G
Sbjct: 210 QTVKEKTLSHLDYRPIPTGKYTVVFSAR-AFLSLLGAFSNLYNAQSILDKQSLATKETLG 268

Query: 261 KKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVP 320
             I SE L V DD   PG   +  +D EG P +RV+IIK+GVL   L+   T+K  +  P
Sbjct: 269 TAIASELLCVSDDALHPGNISAERFDGEGTPTRRVDIIKNGVLTGLLHSAGTAKRFDTQP 328

Query: 321 NGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMF--EEVKFGVYM--IGDKGGQVDIANGS 376
            GH    S   V     ++ Y    E T E+ +  ++ +  VY+  +      V+   GS
Sbjct: 329 TGHANIGSKITVG----AHFYHVYSEKTAEKSYSLDQAENVVYIDKLQALHAGVNSLQGS 384

Query: 377 FMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGFC 427
           F     +G+++ +GE K+ +    ++G+ L+ LK I  +  + ++   G C
Sbjct: 385 FSL-PFDGWLVNKGE-KQSIDAATVAGDFLEVLKTIVYLEPEAEVTPGGVC 433


>dbj|BAB05756.1| (AP001514) unknown conserved protein in others [Bacillus
           halodurans]
           Length = 419
           
 Score = 79.6 bits (193), Expect = 7e-14
 Identities = 53/182 (29%), Positives = 90/182 (49%), Gaps = 3/182 (1%)

Query: 237 EALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVE 296
           +ALG+   AD++ +    L  M GK+I S   T+ D   LP    S  +DDEG+  + + 
Sbjct: 216 KALGNLFIADTIDRSVPALWKMKGKRIASTVFTLKDQAHLPQSIASSPFDDEGVLSQDIT 275

Query: 297 IIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEV 356
           I+  G   + L+   ++   + + NG    +S+   P ++ +N  + PG  + E + +E+
Sbjct: 276 ILAKGTFQHALHSITSASKHHQISNGRAYRKSFDLAPKIQYTNLLVEPGTRSTENLLKEM 335

Query: 357 KFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVG 416
           K G  +     GQ  I  G  MF A +G+ I EG+  E++  V I   +   L+ I AV 
Sbjct: 336 KTGFLINRSFDGQ--IIAGRLMFKA-DGWKIHEGQRVERISRVRIEAPLFQMLRSIVAVA 392

Query: 417 RD 418
           +D
Sbjct: 393 KD 394


>pir||B75180 antibiotic/peptide maturation related protein PAB1956 - Pyrococcus
           abyssi (strain Orsay) >gi|5458031|emb|CAB49521.1|
           (AJ248284) ANTIBIOTIC/PEPTIDE MATURATION related protein
           [Pyrococcus abyssi]
           Length = 448
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 92/426 (21%), Positives = 175/426 (40%), Gaps = 19/426 (4%)

Query: 2   IDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVE-GVESNEEVGI--GVRVLINGW 58
           ++EL    EK+ +E++ +  R       E  VE  ++  G    E+V I  G++    G 
Sbjct: 7   MEELIKYGEKFFDELEIVVRRSRGI---EVNVELNEISMGATRIEKVTIIRGIKDKRVGI 63

Query: 59  GFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQK--KDFLDVDLEEKT 116
               T+   +++  I+ A K+AK++  +   +   P  GK   K K  +D   V  E   
Sbjct: 64  AIIDTDSKEEVKKAIEEAAKMAKLNTPDEK-WSSLPSPGKYREKPKVSEDLKSVSTETLV 122

Query: 117 KLGLEVEKMIRRD--KIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSAD 174
           +      K+ R     +  +  S           NS+G  +       +     V +   
Sbjct: 123 EFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEG 182

Query: 175 IMQTYWKSFGGTVGWEL-VESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGV 233
           ++      F      EL VE V      N    +     + +   + E  +I  P     
Sbjct: 183 VVTPGIFDFDAKDNLELDVEGV-----VNRGLERVKWAYNVKEAKNEETTVIFGPWAISG 237

Query: 234 FIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGK 293
            +  AL  A   + + +  + L+  +G+K+ S+ +T+ DD          + D EG+P +
Sbjct: 238 LLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTR 297

Query: 294 RVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMF 353
           +V +I++G+   ++ D   +K       GHG+         + +++  I  G+  L E+ 
Sbjct: 298 KVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEII 357

Query: 354 EEVKFGVYMIGDKGG-QVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEI 412
            E+K G  + G +G    +  NG+F   A   Y+I++GE+      + I+GN+ + LK+ 
Sbjct: 358 GEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFL-IAGNVYELLKQA 416

Query: 413 KAVGRD 418
             V +D
Sbjct: 417 TEVSKD 422


>pir||I64173 hypothetical protein HI1653 - Haemophilus influenzae (strain Rd
           KW20)
           Length = 122
           
 Score = 76.5 bits (185), Expect = 6e-13
 Identities = 43/118 (36%), Positives = 70/118 (58%), Gaps = 3/118 (2%)

Query: 336 RMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKEGYIIKEGEIKEQ 395
           RM+NTY+  G+   +++   VK G+Y     GGQVDI +G F+F   E Y+I++G+I + 
Sbjct: 3   RMTNTYMLAGQSQFDDLIASVKQGIYAPHFGGGQVDITSGKFVFSTSEAYLIEKGKITKP 62

Query: 396 VRDVGISGNILDTLKEIKAVGRDLKIEFP-GFCGK-GQWVPVDDGGPHVLVKAI-VGG 450
           V+   + G+ ++ +++I  V    +++   G CGK GQ VPV  G P + +  I VGG
Sbjct: 63  VKGATLIGSGIEVMQKISMVADKSELDLGIGVCGKEGQSVPVGVGQPALKIDEITVGG 120


>sp|Q57684|Y231_METJA HYPOTHETICAL PROTEIN MJ0231 >gi|2128001|pir||H64328 hypothetical
           protein MJ0231 - Methanococcus jannaschii
           >gi|1590966|gb|AAB98219.1| (U67479) pmbA protein (pmbA)
           [Methanococcus jannaschii]
           Length = 416
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 103/414 (24%), Positives = 179/414 (42%), Gaps = 31/414 (7%)

Query: 4   ELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLINGW-GFAS 62
           +L  LI+    E    ++ F  +      ++   V+  ++    GIGVRV+ +G  GFA 
Sbjct: 2   DLEKLIKIGEKEGFETEVLFVKSYEVSVDLDGKSVDSFQTGISYGIGVRVIKDGKVGFAY 61

Query: 63  TNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEV 122
            N     E+ +  A+K           +     E K +    K+ LD+D EEK    LE 
Sbjct: 62  ANKFD--ENIVYKAMKNLVEDKYTEFAHPQKYKEPKGMFY--KEILDLD-EEKL---LED 113

Query: 123 EKMIRRDKIKTSRFSYSDFVTRKI----YLNSEGSVIETVVPRIYFSLSAVARSADIMQT 178
              +R   +  +    S  V++++     +NS G  +E      YFS +       IM  
Sbjct: 114 LITMRDIALDNNAIVLSGGVSKEVGYARLINSNGVDVEE--QDTYFSAAI-----SIMYD 166

Query: 179 YWKSFGGTVGWELVESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEA 238
              S+       + +  + +Y A  ++ K+ +  +     S +  I++ P      +   
Sbjct: 167 GETSYECRTRHNIFDVEEISYRALDLAKKSANGKAI----SYKGNIVLSPRALYDLLSYT 222

Query: 239 LGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEII 298
           L  A  A++V++  S+L G IG++I  E +T+IDD TL     S   D EG   ++  ++
Sbjct: 223 LMPAFSAENVQRDRSVLKGKIGEQIFGENITIIDDGTLDYALYSSKCDGEGTATQKTVLV 282

Query: 299 KDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKF 358
           ++GVL NYL D + +        G+  ++ Y  +P V  +N  I   + +L++ F+E   
Sbjct: 283 ENGVLKNYLYDIKRANREGKTSTGNA-SRGYRSLPYVSPTNFIIKETKNSLDD-FDEY-- 338

Query: 359 GVYMIGDKGGQV-DIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKE 411
            VY+ G  G    +   G F    +  Y  K G+I    R +   GNI +  KE
Sbjct: 339 -VYINGVIGSHTSNPITGDFAVEIQNSYYYKNGKIIPIKRGM-FGGNIFEMFKE 390


>emb|CAC11943.1| (AL445065) conserved hypothetical protein [Thermoplasma
           acidophilum]
           Length = 430
           
 Score = 74.9 bits (181), Expect = 2e-12
 Identities = 58/201 (28%), Positives = 96/201 (46%), Gaps = 9/201 (4%)

Query: 220 GEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGK 279
           G   +I+ P  AG  I     +A  A +V  G S L   +G++I +  + + DDPT    
Sbjct: 208 GHYDVILAPMAAGNIITSG-SYAFSAHTVISGLSFLQDSMGRQIAAPMVNLYDDPTDTAG 266

Query: 280 FGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSN 339
               V+D+EG    RV II+ GVL  YL+   T++ +N    G+      A +       
Sbjct: 267 MAYRVFDEEGTATSRVPIIEHGVLNTYLHSTSTARYMNTETTGN------AGIISPEAWQ 320

Query: 340 TYIAPGEWTLEEMFEEVKFGVYMIGDKGGQV-DIANGSFMFGAKEG-YIIKEGEIKEQVR 397
             +  G+ + EE+  + + GV++      +  D  NG F    ++G Y I+ GEI E   
Sbjct: 321 LEMDGGDASAEELISDTREGVFIRNSWYLRFQDYRNGVFSTVPRDGVYYIRNGEIAEAWD 380

Query: 398 DVGISGNILDTLKEIKAVGRD 418
            + IS +I + LK+I A+ ++
Sbjct: 381 GIRISDSIPEILKKISALSKE 401


>gi|11498264 antibiotic maturation protein (pmbA) [Archaeoglobus fulgidus]
           >gi|7429843|pir||H69331 hypothetical protein AF0656 -
           Archaeoglobus fulgidus >gi|2649962|gb|AAB90584.1|
           (AE001059) antibiotic maturation protein (pmbA)
           [Archaeoglobus fulgidus]
           Length = 391
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 93/394 (23%), Positives = 166/394 (41%), Gaps = 57/394 (14%)

Query: 33  VENGKVEGVESNEEVGIGVRVLINGW-GFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYV 91
           +E G+++ V S  +     RV++ G  GFAS    S  ++ + +A K+A++S  E+  + 
Sbjct: 17  IEAGRLKIVSSYVDKSFSARVILKGRVGFASA---STRDEALSLAEKIARISEDELEDFP 73

Query: 92  GN-PVEGKAIIKQKKDFLDVDL--EEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTRKIYL 148
              P   K I  ++ +  D +L  EE  +L   VEK                        
Sbjct: 74  NEKPASVKGIYDKRVEEADSELIMEEFERLRSAVEKA----------------------- 110

Query: 149 NSEGSVIETVVPRIY----FSLSAVARSADIMQTYWKSFGGTVGWELVES----VDFNYW 200
           N   + IE  V  +     F L +  +S          F G   +E+  S    +D    
Sbjct: 111 NIASATIEHAVEEVRITNSFGLDSREKSTSSSMIVEAVFEGGSAYEVCGSRSIELDIEGA 170

Query: 201 ANFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIG 260
           A      A+    A     G   +I+ P      +   L  ++ A++V +G S++   +G
Sbjct: 171 AKKAEELAVDSAKAIKIEGGTYDVILQPIAVHQLLSNTLYPSLSAENVEKGRSVIR--LG 228

Query: 261 KKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVP 320
            + G   +TVIDDPT+ G   S  +DDEG+  ++  +I +GV+ +Y  D + SK   +  
Sbjct: 229 DEFG--RITVIDDPTVEGGLMSCGFDDEGVSARKTFLIDNGVVRSYYTDWKHSKKYGVTG 286

Query: 321 NGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVY-MIGDKGGQVDIANGSFMF 379
           NG    +S    P+V  SN  +      +++  ++    ++ +IG      +  +G F  
Sbjct: 287 NGFRLEESSFPAPMV--SNVVL-----EVDDADDDNCLTIHSLIGSH--TANPVSGDFSL 337

Query: 380 GAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIK 413
                Y    GE  + V+   I GN+ + LK+++
Sbjct: 338 ECNNAYF---GE--KAVKGAMIYGNVFELLKKVE 366


>gb|AAF65318.1|AF234655_1 (AF234655) LmbIH [Streptomyces lincolnensis]
           Length = 199
           
 Score = 69.5 bits (167), Expect = 8e-11
 Identities = 49/170 (28%), Positives = 78/170 (45%), Gaps = 3/170 (1%)

Query: 264 GSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNGH 323
           GSE ++V+ DPT  G  G+  +DDEG P     +I+ G L+  L+ R  + A        
Sbjct: 1   GSEHVSVVADPTGTGA-GATPWDDEGTPTAAAPLIERGTLVGLLSSRTVAAASGRPLTAA 59

Query: 324 GRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQVDIANGSFMFGAKE 383
           G     A +PLVRM+N  + PG  T +++ + +  G+ + G+    +D     F F  + 
Sbjct: 60  GARAEGAALPLVRMTNVNLLPGSGTEQDLLDTMGEGLLLTGNHSFSIDDHREVFHFTCEL 119

Query: 384 GYIIKEGEIKEQVRDVGISGNILDTLKEIKAVG--RDLKIEFPGFCGKGQ 431
            + I+ G+  E +R     G  LD  +    V       +    FC KGQ
Sbjct: 120 AWRIRGGQRVEPLRGPRYHGRTLDFWRSCAHVAGPEAWTMHSVTFCMKGQ 169


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.316    0.138    0.395 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 171487902
Number of Sequences: 2977
Number of extensions: 7576424
Number of successful extensions: 18092
Number of sequences better than 1.0e-10: 58
Number of HSP's better than  0.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 17930
Number of HSP's gapped (non-prelim): 60
length of query: 452
length of database: 189,106,746
effective HSP length: 57
effective length of query: 395
effective length of database: 154,992,987
effective search space: 61222229865
effective search space used: 61222229865
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)