BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0155 (tldE) DE:PMBA PROTEIN (TLDE PROTEIN)
         (427 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus aby...   846  0.0
pir||B71249 hypothetical protein PH0249 - Pyrococcus horikoshii ...   571  e-162
sp|Q57684|Y231_METJA HYPOTHETICAL PROTEIN MJ0231 >gi|2128001|pir...   180  3e-44
pir||B69009 conserved hypothetical protein MTH1070 - Methanobact...   168  1e-40
gi|11498264 antibiotic maturation protein (pmbA) [Archaeoglobus ...   162  7e-39
pir||B75180 antibiotic/peptide maturation related protein PAB195...   120  4e-26
sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir...   113  3e-24
emb|CAB57641.1| (Y18930) hypothetical protein [Sulfolobus solfat...   111  2e-23
gb|AAK40966.1| Zn-dependent protease, tldE protein homolog, puta...   111  2e-23
pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii >gi|3256...   110  3e-23
pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii            109  4e-23
sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|...   109  6e-23
pir||E70461 pmbA protein - Aquifex aeolicus >gi|2984159|gb|AAC07...   106  5e-22
pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii ...   104  1e-21
pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Ors...   100  3e-20
pir||E72342 pmbA-related protein - Thermotoga maritima (strain M...   100  5e-20
pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (st...    98  3e-19
sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG                              93  5e-18
pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii ...    91  2e-17
gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum]                89  1e-16
gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis]          88  2e-16
pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria ...    87  3e-16
pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningit...    87  4e-16
pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (st...    87  5e-16
sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13...    85  2e-15
pir||S75708 hypothetical protein sll0887 - Synechocystis sp. (st...    83  4e-15
pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07...    83  7e-15
gi|11498263 conserved hypothetical protein [Archaeoglobus fulgid...    83  7e-15
pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (st...    82  1e-14
pir||D83086 conserved hypothetical protein PA4474 [imported] - P...    81  2e-14
pir||D72342 tldD protein - Thermotoga maritima (strain MSB8) >gi...    79  1e-13
sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD p...    79  1e-13
pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii ...    78  1e-13
pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (gr...    76  5e-13
dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity...    76  7e-13
sp|P57191|PMBA_BUCAI PMBA PROTEIN HOMOLOG >gi|10038774|dbj|BAB12...    75  2e-12
pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa ...    73  5e-12
sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C6418...    71  2e-11
sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||...    70  4e-11
pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aerugin...    70  4e-11
pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment)         70  5e-11

>pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus abyssi  (strain
           Orsay) >gi|5457662|emb|CAB49153.1| (AJ248283) PMBA
           PROTEIN (TLDE PROTEIN) [Pyrococcus abyssi]
           Length = 427
           
 Score =  846 bits (2163), Expect = 0.0
 Identities = 427/427 (100%), Positives = 427/427 (100%)

Query: 1   MREDVEKLIKILEGSNLNLEWEIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLT 60
           MREDVEKLIKILEGSNLNLEWEIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLT
Sbjct: 1   MREDVEKLIKILEGSNLNLEWEIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLT 60

Query: 61  QGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKIRNL 120
           QGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKIRNL
Sbjct: 61  QGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKIRNL 120

Query: 121 STEEIVEYGTELVDVPPNAEASIGLSTSERGIMNSNGTEGREERTLLAFGLYVFEKSKGT 180
           STEEIVEYGTELVDVPPNAEASIGLSTSERGIMNSNGTEGREERTLLAFGLYVFEKSKGT
Sbjct: 121 STEEIVEYGTELVDVPPNAEASIGLSTSERGIMNSNGTEGREERTLLAFGLYVFEKSKGT 180

Query: 181 GSYSKSFRRLPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFLP 240
           GSYSKSFRRLPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFLP
Sbjct: 181 GSYSKSFRRLPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFLP 240

Query: 241 NVSARNVYLKRSRFTELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGI 300
           NVSARNVYLKRSRFTELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGI
Sbjct: 241 NVSARNVYLKRSRFTELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGI 300

Query: 301 LSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIMISPGNDEQDEGIFIRGIYGEHT 360
           LSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIMISPGNDEQDEGIFIRGIYGEHT
Sbjct: 301 LSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIMISPGNDEQDEGIFIRGIYGEHT 360

Query: 361 ANSVSGDFSLNVDLGYVVRGGEIRPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFASPKI 420
           ANSVSGDFSLNVDLGYVVRGGEIRPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFASPKI
Sbjct: 361 ANSVSGDFSLNVDLGYVVRGGEIRPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFASPKI 420

Query: 421 TTVGKIV 427
           TTVGKIV
Sbjct: 421 TTVGKIV 427


>pir||B71249 hypothetical protein PH0249 - Pyrococcus horikoshii
           >gi|3256638|dbj|BAA29321.1| (AP000001) 426aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 426
           
 Score =  571 bits (1456), Expect = e-162
 Identities = 270/425 (63%), Positives = 349/425 (81%), Gaps = 2/425 (0%)

Query: 3   EDVEKLIKILEGSNLNLEWEIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLTQG 62
           +DVEKL+KIL+  + ++EWEIYW  +SS S KFRKIR+ E+ER ++ VS GIGLR+L  G
Sbjct: 4   DDVEKLVKILK--SFDVEWEIYWESASSLSLKFRKIRRAEIERSTYRVSSGIGLRILVGG 61

Query: 63  KIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKIRNLST 122
           KIGFSY+SGS+F++++LE LVKRA KIAK++G+ YP FPVP K+P++RGLYD +I +LS 
Sbjct: 62  KIGFSYLSGSDFSKDELELLVKRALKIAKISGTEYPAFPVPGKYPSIRGLYDKRIVDLSI 121

Query: 123 EEIVEYGTELVDVPPNAEASIGLSTSERGIMNSNGTEGREERTLLAFGLYVFEKSKGTGS 182
           E++  YGTELV++    EASIG ST  RGIMNSNG EG E R+LL  GLY +EK KG+GS
Sbjct: 122 EDLSYYGTELVNIEVFGEASIGTSTGIRGIMNSNGVEGSENRSLLTLGLYAYEKGKGSGS 181

Query: 183 YSKSFRRLPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFLPNV 242
           Y KSFR LP +E  +E ++E A++EF++S +A+K+EKY GEII+EPKA+ S LSIF+PNV
Sbjct: 182 YGKSFRVLPDMEKVVEEIKETAMFEFKLSREAKKIEKYEGEIIIEPKALISFLSIFVPNV 241

Query: 243 SARNVYLKRSRFTELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILS 302
           SA++VY+KRSRF  LG+EV+S   +IIDDPT++ G+ SYSFDGEGNPG+RKFIIK+G+L+
Sbjct: 242 SAKSVYMKRSRFERLGVEVSSESFSIIDDPTIDEGLGSYSFDGEGNPGMRKFIIKDGVLT 301

Query: 303 SFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIMISPGNDEQDEGIFIRGIYGEHTAN 362
           SFL+DQKYG L+GIGSTGNA R YSSQP I  SN++I  GN+  DEGIFIR +YGEHTAN
Sbjct: 302 SFLSDQKYGSLLGIGSTGNAIRSYSSQPIIDSSNLLIPSGNETLDEGIFIRSVYGEHTAN 361

Query: 363 SVSGDFSLNVDLGYVVRGGEIRPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFASPKITT 422
            ++GDFSLN++LGY+V    ++PFKGNM+VGN+FEMLKNVT+I K +EILD F +PKITT
Sbjct: 362 PITGDFSLNIELGYIVNNRGVKPFKGNMIVGNIFEMLKNVTSIDKNVEILDDFIAPKITT 421

Query: 423 VGKIV 427
            G+IV
Sbjct: 422 WGRIV 426


>sp|Q57684|Y231_METJA HYPOTHETICAL PROTEIN MJ0231 >gi|2128001|pir||H64328 hypothetical
           protein MJ0231 - Methanococcus jannaschii
           >gi|1590966|gb|AAB98219.1| (U67479) pmbA protein (pmbA)
           [Methanococcus jannaschii]
           Length = 416
           
 Score =  180 bits (451), Expect = 3e-44
 Identities = 135/434 (31%), Positives = 219/434 (50%), Gaps = 30/434 (6%)

Query: 4   DVEKLIKILEGSNLNLEWEIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLTQGK 63
           D+EKLIKI  G     E E+ +  S   S     +    V+     +S GIG+RV+  GK
Sbjct: 2   DLEKLIKI--GEKEGFETEVLFVKSYEVSVD---LDGKSVDSFQTGISYGIGVRVIKDGK 56

Query: 64  IGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKIRNLSTE 123
           +GF+Y +  +      E +V +A K   +    Y  F  P+K+   +G++  +I +L  E
Sbjct: 57  VGFAYANKFD------ENIVYKAMK--NLVEDKYTEFAHPQKYKEPKGMFYKEILDLDEE 108

Query: 124 EIVEYGTELVDVPPNAEASI--GLSTSERG---IMNSNGTEGREERTLLAFGLYVFEKSK 178
           +++E    + D+  +  A +  G  + E G   ++NSNG +  E+ T  +  + +     
Sbjct: 109 KLLEDLITMRDIALDNNAIVLSGGVSKEVGYARLINSNGVDVEEQDTYFSAAISIMYD-- 166

Query: 179 GTGSYSKSFRRLPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIF 238
           G  SY    R       ++E +  +AL +    S   K   Y G I+L P+A+  +LS  
Sbjct: 167 GETSYECRTRHNI---FDVEEISYRAL-DLAKKSANGKAISYKGNIVLSPRALYDLLSYT 222

Query: 239 L-PNVSARNVYLKRSRFT-ELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFII 296
           L P  SA NV   RS    ++G ++    +TIIDD T++  + S   DGEG    +  ++
Sbjct: 223 LMPAFSAENVQRDRSVLKGKIGEQIFGENITIIDDGTLDYALYSSKCDGEGTATQKTVLV 282

Query: 297 KEGILSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIMISPGN---DEQDEGIFIR 353
           + G+L ++L D K  +  G  STGNASRGY S P +SP+N +I       D+ DE ++I 
Sbjct: 283 ENGVLKNYLYDIKRANREGKTSTGNASRGYRSLPYVSPTNFIIKETKNSLDDFDEYVYIN 342

Query: 354 GIYGEHTANSVSGDFSLNVDLGYVVRGGEIRPFKGNMLVGNVFEMLKNVTNIGKEIEILD 413
           G+ G HT+N ++GDF++ +   Y  + G+I P K  M  GN+FEM K    +  ++E   
Sbjct: 343 GVIGSHTSNPITGDFAVEIQNSYYYKNGKIIPIKRGMFGGNIFEMFKEAIPL-NDVEQRG 401

Query: 414 GFASPKITTVGKIV 427
              SP +   G+I+
Sbjct: 402 KLISPSVVFKGEII 415


>pir||B69009 conserved hypothetical protein MTH1070 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622168|gb|AAB85559.1| (AE000877) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 430
           
 Score =  168 bits (420), Expect = 1e-40
 Identities = 117/395 (29%), Positives = 193/395 (48%), Gaps = 17/395 (4%)

Query: 37  KIRKVEVER-----GSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAK 91
           K  +VE++R     G  E   GIG+R+L +G++GF+Y S  +   +   R+  +  ++A 
Sbjct: 27  KTLEVEIQRDLIDFGKIESMTGIGIRILKEGRMGFAYTSDPDGV-DVAVRMAAQNLQLAD 85

Query: 92  VAGSIYPGFPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTELVD--VPPNAEASIGLSTSE 149
              +   GF  P  +P+V+G++D    +L  E+ VE    +++  +    + + G  T+ 
Sbjct: 86  PDENF--GFSEPSTYPSVKGIHDRSFDDLEVEDSVEMAGRMINRVLEEGCKPTSGGFTAS 143

Query: 150 R---GIMNSNGTEGREERTLLAFGLYVFEKSKGTGSYSKSFRRLPKLESEIEGVREKALW 206
           R    I+NS G E     T  +  + V     G  + +       KL+   E V  +A  
Sbjct: 144 RIETFILNSEGVEESSSSTGFSAHISVTAGENGMKTTAYESDSSCKLDINPEWVAGRACR 203

Query: 207 EFEMSSKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTE-LGIEVASGG 265
               S   R +E      +L+  A A +L  F    SA NV   RS   + +G +V   G
Sbjct: 204 IARDSMGGRSIESGRIPAVLDYHAAAGLLGTFAGAFSADNVQRGRSVLADRIGSQVTGEG 263

Query: 266 LTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRG 325
           L++ DD T+EGG+ S  FDGEG P  R  ++++GIL  ++ +          STGN  RG
Sbjct: 264 LSVYDDGTLEGGLGSAPFDGEGTPSQRTALVEDGILRGYMHNIYTASKGRADSTGNGLRG 323

Query: 326 YSSQPSISPSNIMISPGND---EQDEGIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGGE 382
           Y   P++S +N ++   +    +   GIF+  + G HTAN +SGDFS+  +  ++   GE
Sbjct: 324 YMEVPAVSTTNFILEFDSTVPLDDFRGIFVTDVLGAHTANPISGDFSVEANNAFMADSGE 383

Query: 383 IRPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFAS 417
             P K  ML GN+FE++  V++   E   + GF +
Sbjct: 384 FTPVKKAMLSGNIFELMMKVSSTDLERRQVGGFVT 418


>gi|11498264 antibiotic maturation protein (pmbA) [Archaeoglobus fulgidus]
           >gi|7429843|pir||H69331 hypothetical protein AF0656 -
           Archaeoglobus fulgidus >gi|2649962|gb|AAB90584.1|
           (AE001059) antibiotic maturation protein (pmbA)
           [Archaeoglobus fulgidus]
           Length = 391
           
 Score =  162 bits (406), Expect = 7e-39
 Identities = 139/395 (35%), Positives = 204/395 (51%), Gaps = 41/395 (10%)

Query: 19  LEWEIYWGVSSSSSFKFR-KIRKVEVERGSFE-----VSGGIGLRVLTQGKIGFSYISGS 72
           +EWE+         F++R K    E+E G  +     V      RV+ +G++GF+  S  
Sbjct: 1   MEWEV---------FEYRTKGIMAEIEAGRLKIVSSYVDKSFSARVILKGRVGFASAS-- 49

Query: 73  NFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTEL 132
             TR++   L   A KIA+++      FP  K   +V+G+YD ++    +E I+E    L
Sbjct: 50  --TRDEALSL---AEKIARISEDELEDFPNEKP-ASVKGIYDKRVEEADSELIMEEFERL 103

Query: 133 ---VDVPPNAEASIGLSTSERGIMNSNGTEGREERTLLAFGLYVFEKSKGTGSYSKSFRR 189
              V+    A A+I  +  E  I NS G + RE+ T  +  + V    +G  +Y     R
Sbjct: 104 RSAVEKANIASATIEHAVEEVRITNSFGLDSREKST--SSSMIVEAVFEGGSAYEVCGSR 161

Query: 190 LPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFL-PNVSARNVY 248
              +E +IEG  +KA      S+KA K+E    ++IL+P AV  +LS  L P++SA NV 
Sbjct: 162 --SIELDIEGAAKKAEELAVDSAKAIKIEGGTYDVILQPIAVHQLLSNTLYPSLSAENVE 219

Query: 249 LKRSRFTELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQ 308
             RS    LG E   G +T+IDDPTVEGG+ S  FD EG    + F+I  G++ S+  D 
Sbjct: 220 KGRS-VIRLGDEF--GRITVIDDPTVEGGLMSCGFDDEGVSARKTFLIDNGVVRSYYTDW 276

Query: 309 KYGHLIGIGSTGNASR-GYSSQPSISPSNIMISPGNDEQDEGIFIRGIYGEHTANSVSGD 367
           K+    G+  TGN  R   SS P+   SN+++   + + D  + I  + G HTAN VSGD
Sbjct: 277 KHSKKYGV--TGNGFRLEESSFPAPMVSNVVLEVDDADDDNCLTIHSLIGSHTANPVSGD 334

Query: 368 FSLNVDLGYVVRGGEIRPFKGNMLVGNVFEMLKNV 402
           FSL  +  Y    GE +  KG M+ GNVFE+LK V
Sbjct: 335 FSLECNNAYF---GE-KAVKGAMIYGNVFELLKKV 365


>pir||B75180 antibiotic/peptide maturation related protein PAB1956 - Pyrococcus
           abyssi (strain Orsay) >gi|5458031|emb|CAB49521.1|
           (AJ248284) ANTIBIOTIC/PEPTIDE MATURATION related protein
           [Pyrococcus abyssi]
           Length = 448
           
 Score =  120 bits (297), Expect = 4e-26
 Identities = 101/387 (26%), Positives = 183/387 (47%), Gaps = 23/387 (5%)

Query: 42  EVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKV--AGSIYPG 99
           E+  G+  +     +R +   ++G + I   +  +E++++ ++ A K+AK+      +  
Sbjct: 39  EISMGATRIEKVTIIRGIKDKRVGIAIIDTDS--KEEVKKAIEEAAKMAKLNTPDEKWSS 96

Query: 100 FPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTELVDVP----PN---AEASIGLSTSERGI 152
            P P K+     + +D ++++STE +VE+ T  + +     PN   A  S G S +E  I
Sbjct: 97  LPSPGKYREKPKVSED-LKSVSTETLVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEI 155

Query: 153 MNSNGTEGREE-RTLLAFGLYVFEKSKGTGSYSKSFRRLPKLESEIEGVREKALWEFEMS 211
            NS G    +E  +   F  +V +K          F     LE ++EGV  + L   + +
Sbjct: 156 FNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWA 215

Query: 212 SKARKLEKYNGEIILEPKAVASILSIFL-PNVSARNVYLKRSRFTE-LGIEVASGGLTII 269
              ++ +     +I  P A++ +LS  L P  S   +  K +   + +G +VAS  +TI 
Sbjct: 216 YNVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIY 275

Query: 270 DDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGY-SS 328
           DD   E  I     DGEG P  +  +I+EGI   F+ D  +  + G  STG+  R +   
Sbjct: 276 DDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGG 335

Query: 329 QPSISPSNIMISPGNDEQDE-------GIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGG 381
             SI  ++ +I  G  E  E       G  + G+ G H++N  +G+F++  +  Y++  G
Sbjct: 336 GVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDG 395

Query: 382 EIRPFKGNMLVGNVFEMLKNVTNIGKE 408
           E+      ++ GNV+E+LK  T + K+
Sbjct: 396 EVVGSTVFLIAGNVYELLKQATEVSKD 422


>sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir||C69214 zinc
           metalloproteinase - Methanobacterium thermoautotrophicum
           (strain Delta H) >gi|2621948|gb|AAB85354.1| (AE000862)
           zinc metalloproteinase [Methanobacterium
           thermoautotrophicum]
           Length = 454
           
 Score =  113 bits (281), Expect = 3e-24
 Identities = 126/447 (28%), Positives = 192/447 (42%), Gaps = 52/447 (11%)

Query: 1   MREDVEKLIKILEGSNLNLEW-EIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVL 59
           M  D + L  IL      +E+ +I  G S +SS   +  +  EV+ G    + G  +RVL
Sbjct: 1   MEIDTDYLGSILMDIEDRVEYADIRAGTSRTSSILMKDGKLQEVKSGR---ASGFRIRVL 57

Query: 60  TQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKIRN 119
             G  GF++        ++  RL + A K  K+ GS+     V    P+V        R 
Sbjct: 58  RNGSWGFAFT-------DEPSRLGEMALKAIKMTGSLRGDVQVGSGAPSVDKTMVRSSRP 110

Query: 120 LSTEEIVEYGTELVDVPPNAEASIGLST--------SERGIMNSNGT--EGREERTLLAF 169
            S     E    + D    A     +ST        S    +NS G+  E  E R  L  
Sbjct: 111 PSDVPAAEKRELVSDAHHAASVDGVVSTTVSYVDMESSSAFLNSEGSLIEMAETRVALFL 170

Query: 170 --------GLYVFEKS-KGTGSYSKSFRRLPKLESEIEGVR--EKALWEFEMSSKARKLE 218
                   G+    KS  GTG     F  L + + E  G R  EKA+       KA    
Sbjct: 171 NAVASDGSGIQFGHKSCGGTGG----FEILEREDIEELGRRTGEKAV----RLLKASPPP 222

Query: 219 KYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTE--LGIEVASGGLTIIDDPTVEG 276
               +I+ +P+     +   L + +  ++ L+     E  LG ++AS G+TIIDDPT++G
Sbjct: 223 SGRFDIVTDPELTGVFIHEALGHAAEADLILQGDSILEGKLGEKIASEGVTIIDDPTIDG 282

Query: 277 GINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSN 336
              SYS+D EG       +++ G+L+S L  ++    +G+  +GNA      QP +  SN
Sbjct: 283 -FGSYSYDAEGVRAAETVLVENGVLTSLLNSRETAFKLGLEPSGNARSAIGDQPIVRMSN 341

Query: 337 IMISPGNDEQDE-------GIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGGEI-RPFKG 388
             + PG+   DE       G+++RG  G    ++  G F  N    + ++ GEI  P K 
Sbjct: 342 TYLKPGDLSFDELIEDIRNGVYLRGSRGGQ-VDTGKGIFQFNAAESFRIQDGEIAEPVKD 400

Query: 389 NMLVGNVFEMLKNVTNIGKEIEILDGF 415
             L GNV E LKNV  +G +  +  GF
Sbjct: 401 VSLSGNVLETLKNVDGVGSDFRLGIGF 427


>emb|CAB57641.1| (Y18930) hypothetical protein [Sulfolobus solfataricus]
           Length = 419
           
 Score =  111 bits (275), Expect = 2e-23
 Identities = 102/404 (25%), Positives = 190/404 (46%), Gaps = 27/404 (6%)

Query: 37  KIRKVEVERGSFEV-----SGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAK 91
           K+R+  + +  F V       G G+R++ +      Y  G  +T++  + +++ A KIAK
Sbjct: 22  KMREYTIAKDKFYVPIIVEETGYGIRLIDE-----KYRIGYIYTKKLNDNVLEEALKIAK 76

Query: 92  VAGSIYPGFPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTELVDVPPNAEASIGLSTSERG 151
           +  S      +P K P V+ + +++I     ++ ++   EL +      AS      E  
Sbjct: 77  LGESDKANI-LPSKQP-VKRINENQINEDVVQDTIKDLIELEEKVNLTSASASAINYEVS 134

Query: 152 IMNSNGTEGREERTLLAFGLYVFEKSKGTGSYSKSFRRLPKLESEIEGVREKALWEFEMS 211
           I N+ G E  E+R +L+      + +     Y    +R  K+   +E ++   + + ++ 
Sbjct: 135 IFNTEGVEVSEKRGVLSVQASANDGNNSPEIYEYLIKRDSKIS--LEKLKASIIEKVKIM 192

Query: 212 SKARKLEKYNGEIILEPKAVASILSIFLPNV-SARNVYLKRSRFTELGIEVASGGLTIID 270
            K  +++    ++    KA+ S+ S   P++ SARN Y + S F +LG E+ +  L IID
Sbjct: 193 KKKERIDPKGYDVTFTQKALDSLFSSLFPSLFSARNFYKETSPF-KLG-ELVNENLEIID 250

Query: 271 DPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASR------ 324
           DP  +    S SFD EGNP     +I+ G++   L +  +   + + +T +ASR      
Sbjct: 251 DPLNQSLPFSRSFDDEGNPSRVSKVIESGLVKRPLTNTYWATRMSVENTSSASRNLDWVV 310

Query: 325 -GYSSQPSISPSNIMISPGNDE---QDEGIFIRGIYGEHTANSVSGDFSLNVDLGYVVRG 380
             Y   P +  SNI+    N E   ++  + +  + G  TA+  SG+FSL  ++ ++ R 
Sbjct: 311 PSYFIPPHVDFSNIIFDYKNTESNIEENSVIVDQLEGIDTADLSSGNFSLVANVSWLNRK 370

Query: 381 GEIRPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFASPKITTVG 424
            E    +  ++ GN+ ++LKN+ +  K IE      S K+   G
Sbjct: 371 DEKIGLEELLITGNLKQLLKNIVSTSKNIENYGKVVSGKLKVRG 414


>gb|AAK40966.1| Zn-dependent protease, tldE protein homolog, putative (tldE)
           [Sulfolobus solfataricus]
           Length = 419
           
 Score =  111 bits (275), Expect = 2e-23
 Identities = 102/404 (25%), Positives = 190/404 (46%), Gaps = 27/404 (6%)

Query: 37  KIRKVEVERGSFEV-----SGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAK 91
           K+R+  + +  F V       G G+R++ +      Y  G  +T++  + +++ A KIAK
Sbjct: 22  KMREYTIAKDKFYVPIIVEETGYGIRLIDE-----KYRIGYIYTKKLNDNVLEEALKIAK 76

Query: 92  VAGSIYPGFPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTELVDVPPNAEASIGLSTSERG 151
           +  S      +P K P V+ + +++I     ++ ++   EL +      AS      E  
Sbjct: 77  LGESDKANI-LPSKQP-VKRINENQINEDVVQDTIKDLIELEEKVNLTSASASAINYEVS 134

Query: 152 IMNSNGTEGREERTLLAFGLYVFEKSKGTGSYSKSFRRLPKLESEIEGVREKALWEFEMS 211
           I N+ G E  E+R +L+      + +     Y    +R  K+   +E ++   + + ++ 
Sbjct: 135 IFNTEGVEVSEKRGVLSVQASANDGNNSPEIYEYLIKRDSKIS--LEKLKASIIEKVKIM 192

Query: 212 SKARKLEKYNGEIILEPKAVASILSIFLPNV-SARNVYLKRSRFTELGIEVASGGLTIID 270
            K  +++    ++    KA+ S+ S   P++ SARN Y + S F +LG E+ +  L IID
Sbjct: 193 KKKERIDPKGYDVTFTQKALDSLFSSLFPSLFSARNFYKETSPF-KLG-ELVNENLEIID 250

Query: 271 DPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASR------ 324
           DP  +    S SFD EGNP     +I+ G++   L +  +   + + +T +ASR      
Sbjct: 251 DPLNQSLPFSRSFDDEGNPSRVSKVIESGLVKRPLTNTYWATRMSVENTSSASRNLDWVV 310

Query: 325 -GYSSQPSISPSNIMISPGNDE---QDEGIFIRGIYGEHTANSVSGDFSLNVDLGYVVRG 380
             Y   P +  SNI+    N E   ++  + +  + G  TA+  SG+FSL  ++ ++ R 
Sbjct: 311 PSYFIPPHVDFSNIIFDYKNTESNIEENSVIVDQLEGIDTADLSSGNFSLVANVSWLNRK 370

Query: 381 GEIRPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFASPKITTVG 424
            E    +  ++ GN+ ++LKN+ +  K IE      S K+   G
Sbjct: 371 DEKIGLEELLITGNLKQLLKNIVSTSKNIENYGKVVSGKLKVRG 414


>pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii
           >gi|3256635|dbj|BAA29318.1| (AP000001) 504aa long
           hypothetical tldd protein [Pyrococcus horikoshii]
           Length = 504
           
 Score =  110 bits (272), Expect = 3e-23
 Identities = 116/445 (26%), Positives = 201/445 (45%), Gaps = 61/445 (13%)

Query: 5   VEKLIKILEGSNLNLEWEIYWGVSSSSSFKFRKIRKVEVERGSFEVSGG----------- 53
           +++++K+LE              SSSS  KF  IR   +E     +  G           
Sbjct: 52  IDEILKVLEK------------YSSSSEIKFMDIRMESIEYTELTIENGKVENLENNGER 99

Query: 54  -IGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAG---SIYPGFPVPKKFPNV 109
            +G+RVL  G   + + S ++ T+  +E +VK A K+AKV+    S+Y   P+       
Sbjct: 100 GVGVRVLING---WGFASTNDLTK--IEEIVKTAIKMAKVSRISTSVYTRDPIEDNVEVK 154

Query: 110 RGLYDDKIRNLSTEEIVEYGTELVDVPPNAEASIGLSTSERGIMNSN--GTEGRE-ERTL 166
           +G+   K++++  EE V+ G E+ ++           +    I+      +EG   E T+
Sbjct: 155 QGI---KLKDIDLEEKVKLGVEVNNMLKRENIKTRKFSYSDIIVKKLYLSSEGSIIESTV 211

Query: 167 LAFGLYVFEKSKGTG---SYSKSFRRLPKLESEIEGVREKALWEFEMSSKARKLEKYNG- 222
               L +   +K +G   +Y KSF      E  +E + +   W   +S KA  L      
Sbjct: 212 PRVYLSISSVAKFSGKMQTYWKSFGGTGGWEI-VEKI-DFEHWANFVSKKAVSLLSARSP 269

Query: 223 -----EIILEPKAVASILSIFLPNVSARNVYLKRSRFTE--LGIEVASGGLTIIDDPTVE 275
                ++I++P+     +   L + S  +   +        LG  +A   LT++DDPT+ 
Sbjct: 270 PSGEMQVIMDPELAGVFIHEALGHASEADAVKQEESILAGMLGKRIAVEELTVVDDPTLP 329

Query: 276 GGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNA-SRGYSSQPSISP 334
           G   SY +D EG PG R  II++G+L ++L D++   L+ +   G+  ++ YS  P +  
Sbjct: 330 GKFGSYIYDDEGIPGKRVEIIRDGVLVNYLNDRETSSLLNLEPNGHGRAQSYSHVPLVRM 389

Query: 335 SNIMISPGN-------DEQDEGIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGGEIR-PF 386
           SN  I PG+       DE   G+++ G  G    +  SG+F      GY+V  GEI+   
Sbjct: 390 SNTYIEPGDWRFEEILDEVKFGVYMIGDKGGQ-VDVASGNFMFAAKEGYLVENGEIKGHL 448

Query: 387 KGNMLVGNVFEMLKNVTNIGKEIEI 411
           +   L GN+   L+ +  IG +++I
Sbjct: 449 RDVALSGNILSALREIKAIGNDLKI 473


>pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii
           Length = 451
           
 Score =  109 bits (271), Expect = 4e-23
 Identities = 107/436 (24%), Positives = 199/436 (45%), Gaps = 36/436 (8%)

Query: 3   EDVEKLIKILEGSNLNLEWEIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLTQG 62
           E +EKL+++ + +++ + +    G S++ + K  KI ++    G+     G+ +RVL   
Sbjct: 5   EKIEKLLEVGDYADIRINF----GESNTITLKDGKIEEISSGFGN-----GVAVRVLY-- 53

Query: 63  KIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYD--DKIRNL 120
           K G+ +++ +  + E++E+L+ +AYK+AK++        + K +  +   Y    KI N 
Sbjct: 54  KNGWGFVTSNIVSEEEIEKLINKAYKMAKISNEYSEKEXILKDYKAIIDNYKMIGKI-NP 112

Query: 121 STEEIVEYGTELVDVPPNAE----ASIGLSTSE----RGIMNSNGTEGREERTLLAFGLY 172
           +  +I E    ++D   N       SI +S S+    R  M S G+    E T     + 
Sbjct: 113 TDVDIEEKKEIIIDTYKNMTDEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMN 172

Query: 173 VFEKSKGTGSYSKSFRR---LPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPK 229
              K  G   Y           K++     +  +A        KA+   K   ++IL+P+
Sbjct: 173 CVAKENGNLQYGAERTGGFGFEKIKDNYLNLALEAKNRALRLLKAKPCPKGKFKVILDPE 232

Query: 230 AVASILSIFLPNVSARNVYLKRSRF--TELGIEVASGGLTIIDDPTVEGGINSYSFDGEG 287
                +   + + S  ++ L+       +LG  V S  +T+IDD T+EG   SY +D EG
Sbjct: 233 LAGVFIHEAVGHASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYKYDDEG 292

Query: 288 NPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIMISPGN---- 343
             G +  II+ GIL ++L  ++    +    TGN      ++P +  SN  I PG+    
Sbjct: 293 VEGKKTVIIENGILKTYLHSRETAGRMDAELTGNGRAEGLNKPIVRMSNTFIKPGDWSFE 352

Query: 344 ---DEQDEGIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGGEI-RPFKGNMLVGNVFEML 399
              ++  EGIF++G  G    ++  G F  +    Y++  GE+ +  K   L G + ++L
Sbjct: 353 ELLEDTKEGIFLKGSRGGQ-VDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGEILDIL 411

Query: 400 KNVTNIGKEIEILDGF 415
             V  + K+ E+  G+
Sbjct: 412 FKVDAVTKDFELSVGY 427


>sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|AAB99001.1| (U67542)
           conserved hypothetical protein [Methanococcus
           jannaschii]
           Length = 451
           
 Score =  109 bits (270), Expect = 6e-23
 Identities = 107/436 (24%), Positives = 199/436 (45%), Gaps = 36/436 (8%)

Query: 3   EDVEKLIKILEGSNLNLEWEIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLTQG 62
           E +EKL+++ + +++ + +    G S++ + K  KI ++    G+     G+ +RVL   
Sbjct: 5   EKIEKLLEVGDYADIRINF----GESNTITLKDGKIEEISSGFGN-----GVAVRVLY-- 53

Query: 63  KIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYD--DKIRNL 120
           K G+ +++ +  + E++E+L+ +AYK+AK++        + K +  +   Y    KI N 
Sbjct: 54  KNGWGFVTSNIVSEEEIEKLINKAYKMAKISNEYSEKEIILKDYKAIIDNYKMIGKI-NP 112

Query: 121 STEEIVEYGTELVDVPPNAE----ASIGLSTSE----RGIMNSNGTEGREERTLLAFGLY 172
           +  +I E    ++D   N       SI +S S+    R  M S G+    E T     + 
Sbjct: 113 TDVDIEEKKEIIIDTYKNMTDEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMN 172

Query: 173 VFEKSKGTGSYSKSFRR---LPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPK 229
              K  G   Y           K++     +  +A        KA+   K   ++IL+P+
Sbjct: 173 CVAKENGNLQYGAERTGGFGFEKIKDNYLNLALEAKNRALRLLKAKPCPKGKFKVILDPE 232

Query: 230 AVASILSIFLPNVSARNVYLKRSRF--TELGIEVASGGLTIIDDPTVEGGINSYSFDGEG 287
                +   + + S  ++ L+       +LG  V S  +T+IDD T+EG   SY +D EG
Sbjct: 233 LAGVFIHEAVGHASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYKYDDEG 292

Query: 288 NPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIMISPGN---- 343
             G +  II+ GIL ++L  ++    +    TGN      ++P +  SN  I PG+    
Sbjct: 293 VEGKKTVIIENGILKTYLHSRETAGRMDAELTGNGRAEGLNKPIVRMSNTFIKPGDWSFE 352

Query: 344 ---DEQDEGIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGGEI-RPFKGNMLVGNVFEML 399
              ++  EGIF++G  G    ++  G F  +    Y++  GE+ +  K   L G + ++L
Sbjct: 353 ELLEDTKEGIFLKGSRGGQ-VDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGEILDIL 411

Query: 400 KNVTNIGKEIEILDGF 415
             V  + K+ E+  G+
Sbjct: 412 FKVDAVTKDFELSVGY 427


>pir||E70461 pmbA protein - Aquifex aeolicus >gi|2984159|gb|AAC07693.1|
           (AE000761) peptide maturation [Aquifex aeolicus]
           Length = 441
           
 Score =  106 bits (262), Expect = 5e-22
 Identities = 96/415 (23%), Positives = 181/415 (43%), Gaps = 34/415 (8%)

Query: 35  FRKIRKVEVERGSFEVSG-------GIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAY 87
           F +++K+++E  + +V         GIG+RVL   ++GFSY S      E+++  V++A 
Sbjct: 22  FERVKKLKIEVSNEQVENVSSSEERGIGIRVLKDKRLGFSYTSFLG--EEEIKDTVEKAM 79

Query: 88  KIAKVAGSIYP-GFPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTELVDVPPNAEASI-GL 145
           ++ ++       GF    K      +YD++  ++  +E +E   ++       +  I G+
Sbjct: 80  EMCEIQEPDEANGFIEKLKPSKAVSVYDEESLSIPLQEKMEIPVKMEKYAKELDKRIVGV 139

Query: 146 STS-------ERGIMNSNGTEGREERTLLAFGLYVFEKSKGTGSYSKSFRRLPKLES-EI 197
             S       E    NS G E     T     +          + S  FR   +L++   
Sbjct: 140 RKSTLTEVEFEVRSFNSFGVEFGYRGTSYTSMIATLGTENDDSAISWEFRGARRLKNLNW 199

Query: 198 EGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFLP----NVSARNVYLKRSR 253
           + + E A+++          E  +  ++   ++ A +L  F P    +   +   L + +
Sbjct: 200 KSMVEDAVFKTVNLLHPSPFETRSMPVVFFRESFAMLLDAFSPMFLGDYLVKGKTLLKDK 259

Query: 254 FTELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHL 313
             E+   VAS  +T++DD ++E G +++ +D EG P  +  +I +G+   FL        
Sbjct: 260 VNEI---VASEKITLVDDGSMEEGFSTFPYDAEGVPTRKNLLIDKGVFKGFLHSLYTARK 316

Query: 314 IGIGSTGNASRG-YSSQPSISPSNIMISPGN-------DEQDEGIFIRGIYGEHTANSVS 365
                TGN+ RG Y   PS   +N  +  GN          DE   +  + G HT +++S
Sbjct: 317 SSQEPTGNSVRGSYKELPSSGTTNFYLEKGNLSFEELLSYYDEVFLVLEVMGLHTVDTIS 376

Query: 366 GDFSLNVDLGYVVRGGEIRPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFASPKI 420
           GDFSL        +G + +  +G  + GN+ ++LKNV  +G ++       SP +
Sbjct: 377 GDFSLGCSGILYKKGKKDKTVRGITVAGNILDLLKNVEEVGNDLTFYGSVGSPSV 431


>pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii
           >gi|3257987|dbj|BAA30670.1| (AP000006) 445aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 445
           
 Score =  104 bits (258), Expect = 1e-21
 Identities = 90/387 (23%), Positives = 177/387 (45%), Gaps = 23/387 (5%)

Query: 42  EVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAG--SIYPG 99
           E+  G+  +S    +R +   +IG S +   N ++E +++ ++ A K+A++      +  
Sbjct: 36  EISMGTTRMSTITIVRGIKDNRIGISIVD--NDSKEDVKKAIEEAAKMARLNNPDDKWKS 93

Query: 100 FPVPKKFPNVRGLYDDKIRNLSTEEIVEY---GTELV-DVPPN---AEASIGLSTSERGI 152
            P P K+   +   +++++  STE +      G +L  +  PN   A  S G S SE  I
Sbjct: 94  LPEPGKYRE-KPKVNEELKEASTETLASMVIKGIQLARESDPNVTVAGGSAGASWSEFSI 152

Query: 153 MNSNGTEGREERTLL-AFGLYVFEKSKGTGSYSKSFRRLPKLESEIEGVREKALWEFEMS 211
            NS+G    +E      F  +V +K          F     L  ++E +  + +   + +
Sbjct: 153 ANSHGVNVTQEYGHAHVFFEFVGKKEGVVTPGIFEFDIKDNLNLDVESIVNRGIERVKWA 212

Query: 212 SKARKLEKYNGEIILEPKAVASILSIFL-PNVSARNVYLKRSRFTE-LGIEVASGGLTII 269
            K ++ +     +I  P A++ +    L P  S   +  K +   + +G ++AS  +TI 
Sbjct: 213 YKVKEAKNEEAPVIFSPWAISGLFHYALFPAFSGERLIKKTTPLADKVGEKIASDVITIY 272

Query: 270 DDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGY-SS 328
           DD   E  +     DGEG P  +  +I+ G+   F+ D  +  + G  STG+  R +   
Sbjct: 273 DDTFHELSVVKAIADGEGVPTRKTMLIENGVFKGFIWDNYWAKVYGTESTGHGQRDWRGG 332

Query: 329 QPSISPSNIMISPGNDEQDE-------GIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGG 381
             +I  ++ +I  G    +E       G  + G+ G H++N  +G+F+++ +  Y++  G
Sbjct: 333 GVTIGLNSAVIENGKRSLEEMIQDIKHGYLVEGVQGAHSSNPDNGNFAISANPAYLIEDG 392

Query: 382 EIRPFKGNMLVGNVFEMLKNVTNIGKE 408
           EI      ++  N++E+LK  + + KE
Sbjct: 393 EIAGSTVFLVASNIYELLKQASEVSKE 419


>pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Orsay)
           >gi|5457661|emb|CAB49152.1| (AJ248283) TLDD PROTEIN
           [Pyrococcus abyssi]
           Length = 452
           
 Score =  100 bits (247), Expect = 3e-20
 Identities = 112/400 (28%), Positives = 190/400 (47%), Gaps = 43/400 (10%)

Query: 40  KVEVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGS---I 96
           KVE    + EV  GIG+RVL  G   + + S ++ ++  LE  +K A K+AKV+ +   +
Sbjct: 37  KVEGVESNEEV--GIGVRVLING---WGFASTNDLSK--LEDTIKMAIKLAKVSNAEVPL 89

Query: 97  YPGFPVPKKFPNVRGLYDDK--IRNLSTEEIVEYGTELV-----DVPPNAEASIGLSTSE 149
           Y G PV  K      +   K    ++  EE  + G E+      D    +  S     + 
Sbjct: 90  YVGNPVEGK-----AIIKQKKDFLDVDLEEKTKLGLEVEKMIRRDKIKTSRFSYSDFVTR 144

Query: 150 RGIMNSNGTEGREERTLLAFGLYVFEKSKGT-GSYSKSFRRLPKLESEIEGVREKALWEF 208
           +  +NS G+        + F L    +S     +Y KSF      E  +E V +   W  
Sbjct: 145 KIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGTVGWEL-VESV-DFNYWAN 202

Query: 209 EMSSKARKL----EKYNGE--IILEPKAVASILSIFLPN-VSARNVYLKRSRFTEL-GIE 260
            +SSKA  L       +GE  II++P+     +   L + V A +V    S  + + G +
Sbjct: 203 FISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEADSVRQGESILSGMIGKK 262

Query: 261 VASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTG 320
           + S  LT+IDDPT+ G   SY +D EG PG R  IIK+G+L ++L D++    + +   G
Sbjct: 263 IGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNYLNDRETSKALNLVPNG 322

Query: 321 NA-SRGYSSQPSISPSNIMISPGN-------DEQDEGIFIRGIYGEHTANSVSGDFSLNV 372
           +  ++ Y+  P +  SN  I+PG        +E   G+++ G  G    +  +G F    
Sbjct: 323 HGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDKGGQ-VDIANGSFMFGA 381

Query: 373 DLGYVVRGGEIRPFKGNM-LVGNVFEMLKNVTNIGKEIEI 411
             GY+++ GEI+    ++ + GN+ + LK +  +G++++I
Sbjct: 382 KEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKI 421


>pir||E72342 pmbA-related protein - Thermotoga maritima (strain MSB8)
           >gi|4981252|gb|AAD35809.1|AE001743_11 (AE001743)
           pmbA-related protein [Thermotoga maritima]
           Length = 435
           
 Score = 99.8 bits (245), Expect = 5e-20
 Identities = 75/251 (29%), Positives = 122/251 (47%), Gaps = 18/251 (7%)

Query: 180 TGSYSKSFRRLPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFL 239
           +GS+ +  R    L  E  G R        + SK     KY   +++   A+  ++ +F+
Sbjct: 183 SGSWYELARTPEDLNPEEIGKRAAEEAISLIGSKTIPSGKY--PVLMRNTALLDLMEMFI 240

Query: 240 PNVSARNVYLKRSRFT-ELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKE 298
           P +SA NV    S    +LG +V +  ++I D P    G++S  FD EG P   KF+++ 
Sbjct: 241 PMISAENVQKNLSPLKGKLGEQVGNPAVSIKDLPYHPKGLSSTPFDDEGVPTTEKFVLEN 300

Query: 299 GILSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIMISPGN-------DEQDEGIF 351
           G+L +FL + K     G+  TGN   G      I P N+M+ PG         E D G+ 
Sbjct: 301 GVLKTFLHNLKTARKEGVEPTGNGFVG-----GIRPVNLMLMPGEKSFEELLKEMDRGVV 355

Query: 352 IRGIYGEHT-ANSVSGDFSLNVDLGYVVRGGEIRPFKGNMLV-GNVFEMLKNVTNIGKEI 409
           I  + G H  ANS+SG+FSL    GY V  GEI     ++ + GN  ++L+ +  +G ++
Sbjct: 356 ITEVEGMHAGANSISGEFSLFAK-GYWVENGEIAHGVEDITISGNFLDLLRKIVLVGNDV 414

Query: 410 EILDGFASPKI 420
           ++     +P +
Sbjct: 415 KVSQHTIAPSV 425


>pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (strain PCC 6803)
           >gi|1652621|dbj|BAA17541.1| (D90907) PmbA protein
           [Synechocystis sp.]
           Length = 427
           
 Score = 97.5 bits (239), Expect = 3e-19
 Identities = 115/428 (26%), Positives = 189/428 (43%), Gaps = 51/428 (11%)

Query: 22  EIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLER 81
           E+Y+  S S    F   R  ++E    E   G+ LR+   G+ G +   G      + E 
Sbjct: 21  EVYYSRSFSRPVFFEANRLKQLESSESE---GVALRLWKNGQAGLAVAYGP----VEPEI 73

Query: 82  LVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKI-RNLSTEEIVEYG--------TEL 132
           LV++A  +A    ++ P  P P +F   R  Y + +  ++S E+++++G        +E 
Sbjct: 74  LVEKALALA----ALNP--PNPPRFTAPRQDYRESLGEDVSVEQLIDWGQTAIASLRSEF 127

Query: 133 VDVPPNAEASIGLSTSERGIMNSNGTEGR-EERTL-LAFGLYVFEKSKGTGSYS-KSFRR 189
            +V  + E  +  ST    ++NS G +    ER+L   FG+           Y  +  R 
Sbjct: 128 AEVLCSGE--LACSTDSTRLINSEGLDCTWTERSLSYYFGVEWIRGEDFLAIYDGEQCRG 185

Query: 190 LPKLESEIEGVREKALW-EFEMSSKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVY 248
              +   +E +R++ LW E     +  K+      I+L   A + +       +  + V 
Sbjct: 186 QTNVGQVVENLRQRLLWVEVNQQIQGGKMP-----ILLTSGAASLLWDTVGEALHGQRVA 240

Query: 249 LKRSRFTE-LGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLAD 307
              S + E LG  VA   L I  DPT         FD EG+   +  +IK G ++ F  D
Sbjct: 241 EDSSPWAEKLGQTVAIEELNISQDPTAIPF--DCPFDDEGSRTQKLALIKNGKIAQFYTD 298

Query: 308 QKYGHLIGIGSTGNASR---GYSSQPSISPSNIMISPGNDEQDE-------GIFIRGIYG 357
            +    +G  +TGN  R   G + QP +   N++I+PG    D+       G+ +  I G
Sbjct: 299 HETAEKLGTTTTGNGFRPSLGSAPQPGLV--NMLITPGTASFDQLLKKLGNGLVVDQILG 356

Query: 358 EHTANSVSGDFSLNVDLGYVVRGGEIR-PFKGNMLVGNVFEMLKNVTNIGKEIEILDGFA 416
                 +SGDFS+NVDLGY V+ GEI    K  M+ GN++E+L  +  +G +       A
Sbjct: 357 GGA--DISGDFSINVDLGYRVQNGEITGRVKDTMVSGNIYELLNQIIALGSDRRWQGSCA 414

Query: 417 SPKITTVG 424
           +P I   G
Sbjct: 415 TPSIILDG 422


>sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG
           Length = 482
           
 Score = 93.2 bits (228), Expect = 5e-18
 Identities = 107/431 (24%), Positives = 188/431 (42%), Gaps = 44/431 (10%)

Query: 15  SNLNLEW-EIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLTQGKIGFSYISGSN 73
           S+ N+++ ++Y+ +S   S+    +    ++ GSF +  G+G+R ++  K GF+Y    N
Sbjct: 28  SHRNIDYADLYFQLSQDESWV---LEDGIIKEGSFHIDRGVGVRAVSGEKTGFAYADQIN 84

Query: 74  FTREQLERLVKRAYKIAKVA-GSIYPGFPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTEL 132
                L++  +    IA+V  G++          P  R    + + +L+ E+ +E    L
Sbjct: 85  LA--SLQQCAEAVKGIAQVKQGNLISPSAFNVVNPIARYAAINPLESLTKEKKIEL-LHL 141

Query: 133 VDVPPNAE--------ASIGLSTSERGIMNSNGTEGREERTLLAFGLYVFEKSKGT---G 181
           VD    AE        AS+     E  IM ++GT   + R L+   + V  +  G    G
Sbjct: 142 VDRTARAEDHRVTKVSASLSSVYEEVLIMATDGTLAADIRPLVRLSISVLVEENGKRERG 201

Query: 182 SYSKSFR-RLPKLESEIEGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASI-LSIFL 239
           S     R  L      ++G     L+  E   +A      N   +  P  +  + L    
Sbjct: 202 SCGSGGRFGLDWFFEVVDGDIRAVLFAKEAVRQAL----VNLSAVAAPAGLMPVVLGAGW 257

Query: 240 PNVSARNVY----------LKRSRFT-ELGIEVASGGLTIIDDPTVEGGINSYSFDGEGN 288
           P V                 + S FT ++G +V S   TI+DD T+E    S + D EG 
Sbjct: 258 PGVLLHEAVGHGLEGDFNRKESSLFTGKIGEQVTSPLCTIVDDGTIENRRGSLTIDDEGV 317

Query: 289 PGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASR-GYSSQPSISPSNIMISPGNDEQD 347
           P     +IK+GIL  ++ D+    L+G+ +TGN  R  Y+  P    +N  +  G  + D
Sbjct: 318 PSQCNVLIKDGILQGYMQDKMNARLMGVSTTGNGRRESYAHLPMPRMTNTYMLAGQSQFD 377

Query: 348 EGI--FIRGIYGEH----TANSVSGDFSLNVDLGYVVRGGEI-RPFKGNMLVGNVFEMLK 400
           + I    +GIY  H      +  SG F  +    Y++  G+I +P KG  L+G+  E+++
Sbjct: 378 DLIASVKQGIYAPHFGGGQVDITSGKFVFSTSEAYLIEKGKITKPVKGATLIGSGIEVMQ 437

Query: 401 NVTNIGKEIEI 411
            ++ +  + E+
Sbjct: 438 KISMVADKSEL 448


>pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii
           >gi|3257986|dbj|BAA30669.1| (AP000006) 458aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 458
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 100/396 (25%), Positives = 172/396 (43%), Gaps = 39/396 (9%)

Query: 49  EVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPN 108
           +++ G+ +RVL  G  GFS    S    +++E  +K AYK+AKVA           +   
Sbjct: 48  KLNRGVAIRVLVNGAWGFS----STSELDKVEEAIKEAYKLAKVASETKKEKIKLAEIKP 103

Query: 109 VRGLYDDKI----RNLSTEEIVEYGTELVDVPPNAEA--SIGLSTSERG----IMNSNGT 158
           V      K+    R +  EE + +  EL ++    +A  S+ +   + G    ++ + GT
Sbjct: 104 VEDFVKSKMKIKPREVDIEEKINHLKELENLLKEDKAVKSVNIRYEDGGGQKILLTNEGT 163

Query: 159 EGREERTLLAFGLYVFEKSKGT--------GSYSKSFRRLPKLESEIEGVREKALWEFEM 210
           +   +   L  G+YV  K  G         G+    +  + + E   E VR++ L +   
Sbjct: 164 KIEWDYNYLWQGVYVTGKEDGKLAMARDTIGAVDYGWELMTEKEPN-EKVRDRILRKLHS 222

Query: 211 SSKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTELGIEVASGGLTIID 270
             K    ++    ++  P  V  I    L +++  ++ +       LG ++A   +T+  
Sbjct: 223 QLKGITPKRGEFPVVAGPIIVGIIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTM-S 281

Query: 271 DPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNA-SRGYSSQ 329
           +  VEGG  +  +D EG P     II+ GIL   + +++Y     +   G+A ++ Y   
Sbjct: 282 ERHVEGGFGNDKYDDEGVPVRDIHIIENGILKEIMLNREYATKFNMEPNGHARAQDYRYP 341

Query: 330 PSISPSNIMISPGN---DEQDEGIFIRGIY------GEHTANSVSGDFSLNVDLGYVVRG 380
           P I   N +  PG+   +E  E I   G Y      G+   NS    F + +  GYV+R 
Sbjct: 342 PIIRMRNTVFEPGDWSFEEMIEDIKF-GYYLVDFRGGQAQLNSA---FQVGIQEGYVIRN 397

Query: 381 GEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEILDGF 415
           GEI  P +   + G   E LK +T +GK+  I  GF
Sbjct: 398 GEIAEPIRDTSITGVAIEALKKITAVGKDFGIEVGF 433


>gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum]
           Length = 479
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 103/426 (24%), Positives = 178/426 (41%), Gaps = 44/426 (10%)

Query: 22  EIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLER 81
           E++   S + +  F   R   +++ +++ S G GLR +    +G+++ S  +     L  
Sbjct: 39  ELFLEYSQTEALMFDNGR---LKQATYDTSQGFGLRAVKDDAVGYAHSSDVS-----LPA 90

Query: 82  LVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKIRNLSTEE-----IVEYGTELVDVP 136
           L++ A  +A V G     F  P    NVR   DD   +    E     + E    L D  
Sbjct: 91  LIRAADAVAAVRGGYSGSFSAPPPHTNVRLYGDDNPLDAPGFETKVKLLAEIDAYLRDKD 150

Query: 137 PNAE---ASIGLSTSERGIMNSNGTEGREERTLLAFGLYVF--------EKSKGTGSYS- 184
           P       ++G +     I+  +G   R+ R L+   + V           SKG G  + 
Sbjct: 151 PRVRQVSVTLGATWQVVEILRPDGESYRDIRPLVRVNISVVAGQGDRQESGSKGYGGRAG 210

Query: 185 -KSFRRLPKLESEIEGVREKALWEFE-MSSKARKLEKYNGEIILEPKAVASILSIFLPNV 242
              F          +G   +AL   E + + A +++     ++L       +L   + + 
Sbjct: 211 YAEFIESKNWRDAADGALREALVNLESIPAPAGEMD-----VVLGAGWPGVMLHEAVGHG 265

Query: 243 SARNVYLKR-SRFTEL-GIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGI 300
              +   KR S F  L G +VA+ G+T++DD T+     S S D EG P  R  +I++GI
Sbjct: 266 LEGDFNRKRTSAFAGLMGRQVAAKGVTVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGI 325

Query: 301 LSSFLADQKYGHLIGIGSTGNASR-GYSSQPSISPSNIMISPGNDEQDE-------GIFI 352
           L  ++ D++   L+ +  TGN  R GY+  P    +N  +  G+ +  E       G+F 
Sbjct: 326 LVGYMQDRQNARLMNMKPTGNGRRQGYAHVPMPRMTNTYMLAGDRDPAEILASVKNGVFA 385

Query: 353 RGIYGEHTANSVSGDFSLNVDLGYVVRGGEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEI 411
              +G    +  SG +       Y +  G+I  P KG ML+GN    L  +  IG ++ +
Sbjct: 386 AN-FGGGQVDITSGKYVFQCTEAYKIENGKIGAPLKGAMLIGNGPTDLHRIRMIGNDLAL 444

Query: 412 LDGFAS 417
             G  +
Sbjct: 445 DTGIGT 450


>gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis]
           Length = 448
           
 Score = 87.8 bits (214), Expect = 2e-16
 Identities = 95/386 (24%), Positives = 164/386 (41%), Gaps = 71/386 (18%)

Query: 54  IGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLY 113
           IGLR+    +   + +S S+F++E L+ LV+RA  +A+ A                    
Sbjct: 56  IGLRLFIGHRS--ASVSSSDFSKEALDALVERAVAMAREAP------------------- 94

Query: 114 DDKIRNLSTEEIVEYGT-------ELVDVPPNAEASIGLSTSER-----GIMNSNGTEGR 161
           +D+   L+ +E++  GT       +  ++ P     + L   +      GI NS G    
Sbjct: 95  EDRWAGLAPKELLMQGTAPEIESDDGKEIAPAVLRELALKAEDAARSVDGITNSEGASAS 154

Query: 162 EERTLLAFGLYV-FEKSKGTGSYSKSF-------------------RRLPKLES-EIEGV 200
             RT+ A      F +   + SY  S                    R    L++ E+ G 
Sbjct: 155 AGRTIFALATSEGFTRGSSSSSYGCSACVIAGQGVNMQRDYDFHATRYFEDLDAAELIGT 214

Query: 201 R--EKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTE-L 257
           R  E+ +     +    +++     II +P+  +  LS  +  +S   +  K S   + L
Sbjct: 215 RAAERTIARLNPT----RIDSGQMPIIFDPRVGSGFLSYLIQGISGGAITRKTSFLLDSL 270

Query: 258 GIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIG 317
           G  V + G+TI +DP  + GI S +FDGEG P     II +G L+ +L D      +G+ 
Sbjct: 271 GKPVFNEGITIKEDPWRKRGIASRAFDGEGLPTKPNNIIDKGRLNGWLLDSAAARQLGMT 330

Query: 318 STGNASRGYSSQPSISPSNIMISPGNDEQDE-------GIFIRGIYGEHTANSVSGDFSL 370
            TG+A RG    PS   +N+ +  G    +E       GI++  + G    N ++GD+S 
Sbjct: 331 PTGHARRGVGGPPSTGTANLYLEAGKVTPEELMSDIKLGIYVTEMIGS-GVNMITGDYSR 389

Query: 371 NVDLGYVVRGGEI-RPFKGNMLVGNV 395
               G+++R G++  P     + GN+
Sbjct: 390 GAS-GFIIRDGQLAEPVAEITVAGNL 414


>pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria meningitidis
           (group A strain Z2491) >gi|7379119|emb|CAB83668.1|
           (AL162752) TLDD protein homolog [Neisseria meningitidis
           Z2491]
           Length = 480
           
 Score = 87.4 bits (213), Expect = 3e-16
 Identities = 98/401 (24%), Positives = 172/401 (42%), Gaps = 39/401 (9%)

Query: 43  VERGSFEVSGGIGLRVLTQGKIGFSY-----ISGSNFTREQLERLVKRAYKIAKVAGSIY 97
           V+ GSF+++ G+G+R ++  K  F+Y     I   N +   +  +     K++    S  
Sbjct: 57  VKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDSINRSARAVRAIGAAGGKVSAKMPSET 116

Query: 98  PGFPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTELVDVPPNAEASIGLSTSERGIMNS-- 155
            G PV      + GL  D    ++    VE   +  D P   +   GL+     +  +  
Sbjct: 117 RGKPVCSASDPIAGL--DSAAKVALLNKVEAIAKAAD-PRIVQVMAGLTCEYDMVYLARL 173

Query: 156 NGTEGREERTLLAFGLYVFEK---------SKGTGSYSKSFRRLPKLESEIEGVREKALW 206
           +G    + R ++   + V  K         + G G Y  ++     +   ++   ++AL 
Sbjct: 174 DGKHAADIRPMVRLNVTVIAKQGERREQGSAGGGGRYDLAYFDENLVRQFVDAAVKQALT 233

Query: 207 EFEMS-SKARKLEKYNGE----IILEPKAVASILSIFLPNVSARNVYLKRSRFTELGIEV 261
             E   + A ++    G     ++L       +   F  N    +V+  R     +G  V
Sbjct: 234 NLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLEGDF--NRKGTSVFSGR-----IGERV 286

Query: 262 ASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGN 321
           A+ G+T++D   + G   S + D EGN   R  +I++GIL  ++ D+    L G  STGN
Sbjct: 287 AAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILVGYMQDETNARLTGTQSTGN 346

Query: 322 ASR-GYSSQPSISPSNIMISPGNDEQDEGI--FIRGIY----GEHTANSVSGDFSLNVDL 374
             R  Y+S P    +N  +  G+ E +E I    +GIY    G    +  SG F  +   
Sbjct: 347 GRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVNFGGGQVDITSGKFVFSASE 406

Query: 375 GYVVRGGEIR-PFKGNMLVGNVFEMLKNVTNIGKEIEILDG 414
            + V GG ++ P KG  ++GN  E+LK+V+ IG +  +  G
Sbjct: 407 AWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSG 447


>pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningitidis  (group B
           strain MD58) >gi|7227328|gb|AAF42385.1| (AE002556) tldD
           protein [Neisseria meningitidis MC58]
           Length = 480
           
 Score = 87.0 bits (212), Expect = 4e-16
 Identities = 98/401 (24%), Positives = 172/401 (42%), Gaps = 39/401 (9%)

Query: 43  VERGSFEVSGGIGLRVLTQGKIGFSY-----ISGSNFTREQLERLVKRAYKIAKVAGSIY 97
           V+ GSF+++ G+G+R ++  K  F+Y     I   N +   +  +     K++    S  
Sbjct: 57  VKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDSINRSARAVRAIGAAGGKVSAKMPSET 116

Query: 98  PGFPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTELVDVPPNAEASIGLSTSERGIMNS-- 155
            G PV      + GL  D    ++    VE   +  D P   +   GL+     +  +  
Sbjct: 117 RGKPVCSASDPIAGL--DSAAKVALLNKVEAIAKAAD-PRIVQVMAGLTCEYDMVYLARL 173

Query: 156 NGTEGREERTLLAFGLYVFEK---------SKGTGSYSKSFRRLPKLESEIEGVREKALW 206
           +G    + R ++   + V  K         + G G Y  ++     +   ++   ++AL 
Sbjct: 174 DGKHAADIRPMVRLNVTVIAKQGERREQGSAGGGGRYDLAYFDENLVHRFVDAAVKQALT 233

Query: 207 EFEMS-SKARKLEKYNGE----IILEPKAVASILSIFLPNVSARNVYLKRSRFTELGIEV 261
             E   + A ++    G     ++L       +   F  N    +V+  R     +G  V
Sbjct: 234 NLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLEGDF--NRKGTSVFSGR-----IGERV 286

Query: 262 ASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGN 321
           A+ G+T++D   + G   S + D EGN   R  +I++GIL  ++ D+    L G  STGN
Sbjct: 287 AAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILVGYMQDETNARLTGTQSTGN 346

Query: 322 ASR-GYSSQPSISPSNIMISPGNDEQDEGI--FIRGIY----GEHTANSVSGDFSLNVDL 374
             R  Y+S P    +N  +  G+ E +E I    +GIY    G    +  SG F  +   
Sbjct: 347 GRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVNFGGGQVDITSGKFVFSASE 406

Query: 375 GYVVRGGEIR-PFKGNMLVGNVFEMLKNVTNIGKEIEILDG 414
            + V GG ++ P KG  ++GN  E+LK+V+ IG +  +  G
Sbjct: 407 AWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSG 447


>pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (strain Orsay)
           >gi|5458032|emb|CAB49522.1| (AJ248284) TLDD RELATED
           PROTEIN [Pyrococcus abyssi]
           Length = 458
           
 Score = 86.6 bits (211), Expect = 5e-16
 Identities = 98/396 (24%), Positives = 169/396 (41%), Gaps = 39/396 (9%)

Query: 49  EVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPN 108
           +++ G+ +RVL  G  GFS  S  +    +LE  +K AYK+AK A           +   
Sbjct: 48  KLNRGVAIRVLANGAWGFSSTSDLS----KLEEAIKEAYKLAKSASETKKEKIELAEIKP 103

Query: 109 VRGLYDDKI----RNLSTEEIVEYGTELVDVPPNAEA--SIGLSTSERG----IMNSNGT 158
           V      K+    R +  EE V++ TEL  +    E   S+ +   + G    ++ + GT
Sbjct: 104 VEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGT 163

Query: 159 EGREERTLLAFGLYVFEKSKGT--------GSYSKSFRRLPKLESEIEGVREKALWEFEM 210
               +   L   +YV  K +G         G+    +  + + E   E V+++ L +   
Sbjct: 164 RIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDYGWELMTEKEPN-EKVKDRLLRKLHS 222

Query: 211 SSKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTELGIEVASGGLTIID 270
                  ++    ++  P  V  I    L +++  ++ +       LG ++A   +T+  
Sbjct: 223 QLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTM-S 281

Query: 271 DPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNA-SRGYSSQ 329
           +  VEGG  +  +D EG P     II+ GIL   + +++Y     +   G+A ++ Y   
Sbjct: 282 ERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYP 341

Query: 330 PSISPSNIMISPGN---DEQDEGIFIRGIY------GEHTANSVSGDFSLNVDLGYVVRG 380
           P I   N +  PG+   +E  E I   G Y      G+   NS    F + +  GYV+R 
Sbjct: 342 PIIRMRNTVFEPGDWSFEEMIEDIKF-GYYLVDFRGGQAQLNSA---FQVGIQEGYVIRN 397

Query: 381 GEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEILDGF 415
           GEI  P +   + G   E LK ++ +GK+  I  GF
Sbjct: 398 GEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGF 433


>sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13101.1| (AP001119) tldD
           protein [Buchnera sp. APS]
           Length = 483
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 52/168 (30%), Positives = 89/168 (52%), Gaps = 12/168 (7%)

Query: 257 LGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGI 316
           +G +VAS   TIIDD T++    S S D EG PG +  +I+ GIL  ++ D+    L+G+
Sbjct: 287 IGKKVASELCTIIDDGTIKNQRGSLSIDDEGTPGQKNILIENGILKKYMQDKLNARLMGV 346

Query: 317 GSTGNASR-GYSSQPSISPSNIMISPGNDEQDEGIFIRGI-YGEHTAN-------SVSGD 367
            STGN  R  YS  P    +N  +  G  + D+   I+ + YG +  N         SG 
Sbjct: 347 KSTGNGRRESYSCLPMPRMTNTYMLSGKSKLDD--IIKSVDYGIYAVNFSGGQVDITSGK 404

Query: 368 FSLNVDLGYVVRGGEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEILDG 414
           F  +    Y+++ G+I  P K   L+G+  E+++ ++ +G ++++ +G
Sbjct: 405 FVFSTSEAYLIKNGKIVTPIKNTTLIGSGLEVMQKISMVGDDLKMDEG 452


>pir||S75708 hypothetical protein sll0887 - Synechocystis sp. (strain PCC 6803)
           >gi|1001203|dbj|BAA10443.1| (D64003) hypothetical
           protein [Synechocystis sp.]
           Length = 446
           
 Score = 83.5 bits (203), Expect = 4e-15
 Identities = 83/298 (27%), Positives = 131/298 (43%), Gaps = 22/298 (7%)

Query: 144 GLS--TSERGIMNSNGTEGREERTLLAFGLYVFEKSKGTGSYS----KSFRRLPKLESE- 196
           GLS  T+ER  +NS G +  E R+  +  LY   + +G    S    K  R L  L+ + 
Sbjct: 148 GLSEQTTERFYLNSAGAKRYECRSYASIYLYSRAEQEGKKPRSAGEMKISRDLASLDIDG 207

Query: 197 -IEGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFT 255
            ++ V+EK L   +     R +      ++   +A  S+L  F    +A+++  K+S  T
Sbjct: 208 CLQTVKEKTLSHLDY----RPIPTGKYTVVFSARAFLSLLGAFSNLYNAQSILDKQSLAT 263

Query: 256 E--LGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHL 313
           +  LG  +AS  L + DD    G I++  FDGEG P  R  IIK G+L+  L        
Sbjct: 264 KETLGTAIASELLCVSDDALHPGNISAERFDGEGTPTRRVDIIKNGVLTGLLHSAGTAKR 323

Query: 314 IGIGSTGNASRGYSSQPS------ISPSNIMISPGNDEQDEGIFIRGIYGEHT-ANSVSG 366
                TG+A+ G             S      S   D+ +  ++I  +   H   NS+ G
Sbjct: 324 FDTQPTGHANIGSKITVGAHFYHVYSEKTAEKSYSLDQAENVVYIDKLQALHAGVNSLQG 383

Query: 367 DFSLNVDLGYVVRGGEIRPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFASPKITTVG 424
            FSL  D G++V  GE +      + G+  E+LK +  +  E E+  G   P +   G
Sbjct: 384 SFSLPFD-GWLVNKGEKQSIDAATVAGDFLEVLKTIVYLEPEAEVTPGGVCPLVWVEG 440


>pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07784.1|
           (AE000768) TldD protein [Aquifex aeolicus]
           Length = 404
           
 Score = 82.7 bits (201), Expect = 7e-15
 Identities = 99/391 (25%), Positives = 177/391 (44%), Gaps = 28/391 (7%)

Query: 22  EIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTR-EQLE 80
           EI++  S ++       +  +V  G  E   G+GLR++  GK  + Y +   F   ++L 
Sbjct: 22  EIFYEKSRTTRMHLEDRKIDKVTHGYDE---GVGLRLIKNGKTYYGYTTNPTFENLKELA 78

Query: 81  RLVKRAYKIAKVA-GSIY-PGFPVPKKFPNVRGL-YDDKIRNLSTEEIVEYGTELVDVPP 137
           +++ R      VA G  Y  G+      P+   L +  +I   + E+   +G ++  V  
Sbjct: 79  KILARGEGHGPVAIGKRYIQGYTEVLIDPDKESLKFRAEILRRADEKARSFGDKIKQVL- 137

Query: 138 NAEASIGLSTSERGIMNSNGTEGREERTLLAFGLYVFEKSKGT---GSYSKSFRRLPKLE 194
              A +   T E  ++N+ G    + +  + F + V      T   G  S   RR  ++ 
Sbjct: 138 ---AVLMDKTREIMVINTLGETAEDTQKRVVFFVEVVASDGETLQRGYESLGGRRGFEIF 194

Query: 195 SEI--EGVREKALWEFEMSSKARKLEKYNGEIILEPKAVASILSIFLPN-VSARNVYLKR 251
           +E   E + EKA     +   A+        +++  +A  +++   + + + A  V    
Sbjct: 195 NETPPEVIAEKAAKRALLMLSAKPAPAGTFTVVMSSQAGGTMIHEAVGHGLEADLVQQGL 254

Query: 252 SRFT-ELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKY 310
           S +  +LG +VAS  +T+IDD T+     S++ D EG P  RK +IK+G+L  ++ D+  
Sbjct: 255 SVYAGKLGEKVASELVTVIDDATLPYHNGSFTVDDEGVPAQRKVLIKDGVLVGYMYDRLR 314

Query: 311 GHLIGIGSTGNASR-GYSSQPSISPSNIMISPGNDEQDE-------GIFIRGIYGEHTAN 362
               G+ STGN  R  Y+  P +  +N  I  G D  ++       G+ +  + G    N
Sbjct: 315 AMKDGVESTGNGRRQSYAHIPIVRMTNTFIDKGQDNPEDIIKDTKKGVLVVKM-GGGEVN 373

Query: 363 SVSGDFSLNVDLGYVVRGGEIR-PFKGNMLV 392
           +V+GDF   V  GY++  GEI  P +G  L+
Sbjct: 374 TVTGDFVFEVMEGYMIENGEITYPIRGATLI 404


>gi|11498263 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|3123065|sp|O29602|Y655_ARCFU HYPOTHETICAL PROTEIN
           AF0655 >gi|7429834|pir||G69331 conserved hypothetical
           protein AF0655 - Archaeoglobus fulgidus
           >gi|2649963|gb|AAB90585.1| (AE001059) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 425
           
 Score = 82.7 bits (201), Expect = 7e-15
 Identities = 94/317 (29%), Positives = 148/317 (46%), Gaps = 26/317 (8%)

Query: 118 RNLSTEEIVEYGTELVDVPPNAEASIGLSTSE-RGIMNSNGTEGRE-ERTLLAFGLYVFE 175
           +++S EE VE   +L  +  +   S  L   E R ++    + G E E  +L  G+ +  
Sbjct: 90  QDMSIEEKVELLKDLEKIIRDVCVSTKLVYFENRRVLQYRDSCGSEVEYEVLRTGVSIMG 149

Query: 176 KSKGTGSYSKSFRRLPKLESEI-EGVREKALWEFEMSSK-ARKLEKYNGEI-ILEPKAVA 232
             KG      S R++     E+ +GV EKA    E+  K    L   +GE+ ++   ++A
Sbjct: 150 VGKGRSLQFLSKRQMRVGGYEVLDGVDEKAYEIVEVLPKLVNALAPPSGEMSVVMDSSLA 209

Query: 233 SIL--SIFLPNVSARNVY----LKRSRFTELGIEVASGGLTIIDDPTVEGGINSYSFDGE 286
            +     F   V A +V     + + R  E   +VA   +TIIDDPT+      + FD E
Sbjct: 210 GVFVHEAFGHAVEADHVLQGATVLKGRLNE---KVADESVTIIDDPTLPE-FGFFPFDDE 265

Query: 287 GNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIMISPGNDEQ 346
           G    +K I+++G+L SFL  ++    +G G  GNA       P +  SN  I   +   
Sbjct: 266 GVRAEKKVIVEDGVLKSFLHSRETAKKLG-GVAGNARSQGVDVPIVRMSNTYIDTHHYSF 324

Query: 347 DE-------GIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGGEIRPFKGNM-LVGNVFEM 398
           DE       G+++ G  G  T N  +G F  N   GY+++ GE+     ++ L GN  E+
Sbjct: 325 DELLEECRDGVYLVGSRGGET-NPATGYFHFNAQYGYLIKNGELAEMVRDVSLSGNTLEI 383

Query: 399 LKNVTNIGKEIEILDGF 415
           L+NV  IG+EIE   GF
Sbjct: 384 LRNV-KIGREIEFDPGF 399


>pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (strain Orsay)
           >gi|5458676|emb|CAB50163.1| (AJ248287) hypothetical
           protein [Pyrococcus abyssi]
           Length = 443
           
 Score = 81.9 bits (199), Expect = 1e-14
 Identities = 73/268 (27%), Positives = 124/268 (46%), Gaps = 20/268 (7%)

Query: 152 IMNSNGTEGREERTLLAFGLYVFEKSKGTGSYSKSFRRLPKLESEIEGVREKALWEFEMS 211
           +  SNG E  +E T +   +  F     +G  + S R L K + E  G +   + +   +
Sbjct: 155 LTTSNGVEAFDEGTGIEISVRAFIGDLESGHGTNSVRVLKKFDPESAGRKAGEIAKMARN 214

Query: 212 SKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFT-ELGIEVASGGLTIID 270
            +     K+  ++I +P A A++LS      SA  V    S F  +L  +VAS  +TI D
Sbjct: 215 PEQGPEGKF--DVIFDPLAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEVVTIKD 272

Query: 271 DPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGYSSQP 330
              +  G  +  FD EG P     +I+ G L ++L +       G  +T NA        
Sbjct: 273 IGNLPNGYGTRKFDDEGVPTRETVLIERGTLKTYLFNTSLAKKYGKETTANAG------- 325

Query: 331 SISPS--NIMISPGNDEQDE-------GIFIRGIYGEHTANSVSGDFS-LNVDLGYVVRG 380
            ISP   NI++ PG+  +DE       GI+I  ++     N ++GDFS +  D  +++  
Sbjct: 326 LISPRAWNIVLEPGDYTKDELFQEVKRGIYITNVWYTRFQNYMTGDFSTIPRDGIFLIEN 385

Query: 381 GEIRPFKGNMLVGNVFEMLKNVTNIGKE 408
           GE++P +   +  N+  +L+N+  + KE
Sbjct: 386 GELKPIRNIRVSDNMLRILQNIVGLTKE 413


>pir||D83086 conserved hypothetical protein PA4474 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9950711|gb|AAG07862.1|AE004861_3 (AE004861)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 480
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 96/395 (24%), Positives = 167/395 (41%), Gaps = 26/395 (6%)

Query: 43  VERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVA--GSIYP-G 99
           V+ GSF +  G+G+R  +  K GF+Y +    T E L++    A  I++    GS+    
Sbjct: 57  VKEGSFNLDQGVGVRAQSGEKTGFAYSNA--ITAEALKQAAVAARSISRAGQNGSVQAFK 114

Query: 100 FPVPKKFPNVRGLYDDKIRNLSTEEI--VEYGTELVDVPPNAEASIGLSTSERGIM--NS 155
             VP +        D   R    E +  ++  T  +D P   + ++ ++     I+   S
Sbjct: 115 AVVPARLYAGENPLDVLSRAEKVELLKQIDAATRALD-PRIQQVTVSMAGVWEQILVAAS 173

Query: 156 NGTEGREERTLLAFGLYVFEKSKGT------GSYSKSFRRLPKLESEIEGVREKALWEFE 209
           +G+   + R L+ F + V  +  G       G   ++  R    E    G   +AL +  
Sbjct: 174 DGSLAADIRPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLQEDRAMGYAREALRQAL 233

Query: 210 MSSKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTE--LGIEVASGGLT 267
           ++ +A         +++       +L   + +    +   K S      +G +VAS   T
Sbjct: 234 VNLEAIPAPAGTLPVVMGAGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRVGEKVASSLCT 293

Query: 268 IIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASR-GY 326
           I+DD T+ G   S S D EG P     +I+ G+L  ++ D+    L+G+  TGN  R  Y
Sbjct: 294 IVDDGTLAGRRGSLSVDDEGTPSNCNVLIENGVLKGYMQDKLNARLMGVARTGNGRRESY 353

Query: 327 SSQPSISPSNIMISPGNDEQDEGI--FIRGIY----GEHTANSVSGDFSLNVDLGYVVRG 380
           +  P    +N  +  G  +  E I    +GIY    G    +  SG F  +    Y++  
Sbjct: 354 AHLPMPRMTNTYMLAGESDPQEIIASVEKGIYCANLGGGQVDITSGKFVFSTSEAYLIEN 413

Query: 381 GEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEILDG 414
           G I  P KG  L+GN  E +  V+ +G ++ +  G
Sbjct: 414 GRITTPVKGATLIGNGPEAMSRVSMVGNDLALDSG 448


>pir||D72342 tldD protein - Thermotoga maritima (strain MSB8)
           >gi|4981251|gb|AAD35808.1|AE001743_10 (AE001743) tldD
           protein [Thermotoga maritima]
           Length = 499
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 49/162 (30%), Positives = 86/162 (52%), Gaps = 8/162 (4%)

Query: 256 ELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIG 315
           +LG +VA+  ++ +DD T+  G  S + D EG P  R  +I +G+L  +L D+     +G
Sbjct: 303 KLGQKVAAECVSAVDDATIPNGWGSANVDDEGTPTQRTLLIDKGVLVGYLVDKLGERRMG 362

Query: 316 IGSTGNASR-GYSSQPSISPSNIMISPGNDEQDEGIFIR--GIY----GEHTANSVSGDF 368
           + STG+  R  Y+  P+   SN  I PG+   +E I     G+Y    G  + N  +G+F
Sbjct: 363 MKSTGSGRRQDYTFPPTSRMSNTFILPGDYHPEEIIAATEYGLYAKTMGGGSVNPATGEF 422

Query: 369 SLNVDLGYVVRGGEI-RPFKGNMLVGNVFEMLKNVTNIGKEI 409
           +  V   Y++  G I +P +G  L+G   E+++ +  +G ++
Sbjct: 423 NFAVSEAYLIEKGRITKPVRGATLIGKGHEIIQKIDMVGNDL 464


>sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD protein - Escherichia
           coli (strain K-12) >gi|606183|gb|AAA58046.1| (U18997)
           ORF_f481 [Escherichia coli] >gi|1732437|dbj|BAA07913.1|
           (D44451) TldD protein [Escherichia coli]
           >gi|1789640|gb|AAC76276.1| (AE000403) suppresses
           inhibitory activity of CsrA [Escherichia coli K12]
           Length = 481
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 89/411 (21%), Positives = 168/411 (40%), Gaps = 54/411 (13%)

Query: 43  VERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPV 102
           ++ GS+ +  G+G+R ++  K GF+Y      +   LE+  + A  I + +G    G   
Sbjct: 55  IKDGSYNIDQGVGVRAISGEKTGFAY--ADQISLLALEQSAQAARTIVRDSGD---GKVQ 109

Query: 103 PKKFPNVRGLYD--DKIRNLSTEEIVEYGTELVDVPPNAEASIGLSTSERG-------IM 153
                    LY   D ++++S EE ++    +  V   A+  +   T+          + 
Sbjct: 110 TLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVA 169

Query: 154 NSNGTEGREERTLLAFGLYVFEK---------SKGTGSYSKSFRRLPKLESEIEGVREKA 204
            ++GT   + R L+   + V  +         S G G +   F       ++++G     
Sbjct: 170 ATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEF-----FLADLDGEVRAD 224

Query: 205 LWEFEMSSKARKLEKYNGEIILEPKAVASI-LSIFLPNVSARNV--YLKRSRFTELGIEV 261
            W    + +A ++   N   +  P     + L    P V       +     F   G  V
Sbjct: 225 AW----AKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSV 280

Query: 262 ASGGL---------TIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGH 312
            SG +         T++DD T+     S + D EG PG    +I+ GIL  ++ D+    
Sbjct: 281 FSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNAR 340

Query: 313 LIGIGSTGNASR-GYSSQPSISPSNIMISPGNDEQDE-------GIFIRGIYGEHTANSV 364
           L+G+  TGN  R  Y+  P    +N  + PG     E       GI+    +G    +  
Sbjct: 341 LMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPN-FGGGQVDIT 399

Query: 365 SGDFSLNVDLGYVVRGGEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEILDG 414
           SG F  +    Y++  G++ +P KG  L+G+  E ++ ++ +G ++++ +G
Sbjct: 400 SGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNG 450


>pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii
           >gi|3257260|dbj|BAA29943.1| (AP000003) 443aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 443
           
 Score = 78.4 bits (190), Expect = 1e-13
 Identities = 72/268 (26%), Positives = 124/268 (45%), Gaps = 20/268 (7%)

Query: 152 IMNSNGTEGREERTLLAFGLYVFEKSKGTGSYSKSFRRLPKLESEIEGVREKALWEFEMS 211
           +  SN  E  +E T +   +  F     +G  + S R L K + E  G +   + +   +
Sbjct: 155 LTTSNDVEAFDEGTGIEISVRAFIGDLESGHGTNSVRVLKKFDPESAGRKAGEIAKLARN 214

Query: 212 SKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFT-ELGIEVASGGLTIID 270
            +     ++  ++I +P A A++LS      SA  V    S F  +L  +VAS  +TI D
Sbjct: 215 PEQGPEGRF--DVIFDPLAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEIVTIKD 272

Query: 271 DPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGYSSQP 330
              +  G  +  FD EG P     +I +GIL ++L +       G  +T NA        
Sbjct: 273 VGNLPNGYATRKFDDEGVPTKETILIHKGILKTYLFNTSLAKKYGRETTANAG------- 325

Query: 331 SISPS--NIMISPGNDEQDE-------GIFIRGIYGEHTANSVSGDFS-LNVDLGYVVRG 380
            I+P   NI++ PG+  +DE       GI+I  ++     N ++GDFS +  D  +++  
Sbjct: 326 LIAPRAWNIVLEPGDYTKDELFQEVKKGIYITNVWYTRFQNYMTGDFSTIPRDGIFLIEN 385

Query: 381 GEIRPFKGNMLVGNVFEMLKNVTNIGKE 408
           GE++P +   +  N+  +L+NV  + KE
Sbjct: 386 GELKPIRNIRVSDNMLRILQNVVALSKE 413


>pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9654844|gb|AAF93595.1| (AE004129) tldD
           protein [Vibrio cholerae]
           Length = 481
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 50/164 (30%), Positives = 84/164 (50%), Gaps = 8/164 (4%)

Query: 256 ELGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIG 315
           ++G +V S   TI+DD T++    S + D EG  G    +I++GIL  ++ D+    L+G
Sbjct: 284 KVGKKVTSDLCTIVDDGTLKDLRGSLNVDDEGVSGQYNVLIEKGILKGYIQDKLNARLMG 343

Query: 316 IGSTGNASR-GYSSQPSISPSNIMISPGNDEQDEGI--FIRGIY----GEHTANSVSGDF 368
           +  TGN  R  Y+  P    +N  + PG    +E I    +GIY    G    +  SG F
Sbjct: 344 VAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPEEIIASVKKGIYAPNFGGGQVDITSGKF 403

Query: 369 SLNVDLGYVVRGGEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEI 411
             +    Y++  G+I RP KG  L+G+  E ++ V+ +G ++ +
Sbjct: 404 VFSASEAYLIENGKITRPIKGATLIGSGIEAMQQVSMVGNDLAL 447


>dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity of the cabon
           storage regulator (CsrA) [Bacillus halodurans]
           Length = 432
           
 Score = 76.1 bits (184), Expect = 7e-13
 Identities = 73/274 (26%), Positives = 129/274 (46%), Gaps = 23/274 (8%)

Query: 155 SNGTEGREE-RTLLAFGLYVFEKSKGTGSYSKSFRR-LPKLESEIEGVREKALWEFEMSS 212
           ++ +E +E+ RT      Y+  + +G    S   R  L  +  + E ++E  L+    + 
Sbjct: 128 TSSSELKEDIRTCFMLDFYITVQKEGRTKQSNLTRSWLSPINVQEEDLQELVLYTANAAM 187

Query: 213 K---ARKLEKYNGEIILEPKAVASIL-SIFLPNVSARNVYLKRSRFTE-LGIEVASGGLT 267
           +   AR     +  +IL P A   I   +    + A    + +S F + LG  V    +T
Sbjct: 188 EKLDARPFPSGSYALILGPLAAPGIFHEVVGHGLEADIASIPQSAFHQRLGAMVGCEKVT 247

Query: 268 IIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGH-LIGIGSTGNASRGY 326
           IIDDPT EG   SYS D EG    +  +I++G + ++L+    GH   G G   N    Y
Sbjct: 248 IIDDPTKEGLPGSYSLDDEGTIAQQTTLIEKGRVVNYLSHLHTGHPTNGHGRVIN----Y 303

Query: 327 SSQPSISPSNIMISPGNDEQDE-------GIFI-RGIYGEHTANSVSGDFSLNVDLGYVV 378
              P +  SN  + PG D+ +E       G+++ + I G+   N ++G+F ++V  GY++
Sbjct: 304 QHLPLVRMSNTFLLPGTDDPEEMVSDTEVGLYVKKAINGD--VNMITGEFEIHVAEGYLI 361

Query: 379 RGGEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEI 411
             G+I  P     L G+  ++L+++  +G +  I
Sbjct: 362 EKGQITSPILPTTLKGDGQKLLQSIDRVGNDFAI 395


>sp|P57191|PMBA_BUCAI PMBA PROTEIN HOMOLOG >gi|10038774|dbj|BAB12809.1| (AP001118) pmbA
           protein [Buchnera sp. APS]
           Length = 446
           
 Score = 74.9 bits (181), Expect = 2e-12
 Identities = 101/433 (23%), Positives = 179/433 (41%), Gaps = 51/433 (11%)

Query: 5   VEKLIKILEGSNLNLEWEIYWGVSSSSSFKFRKIRKVEVERGSFEVSGGIGLRVLTQGKI 64
           V+  +K+ +  N ++E  I   +  S +     +R   VE   F   GG+ + V    K 
Sbjct: 18  VKNTLKLSKNINASVEVFIKKTIGISVN-----VRNNVVENVEFNSDGGLFITVYN--KF 70

Query: 65  GFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPNVRGLYDDKIRNLSTEE 124
               +S  +F+ + ++ ++  A  I+K + S +             GL D K     + E
Sbjct: 71  SKGSVSSKDFSIKNIKNMLDIAINISKYSSSDF-----------FSGLPDIKFLCFHSME 119

Query: 125 IVEYGTELVDVPPNAEASI----GLSTSERGIMNSNGTEGREERTLLAFG--LYVFEKSK 178
           +  +     ++    + SI        S++ I+NS G+      T+  FG  L V EK K
Sbjct: 120 LDLFHPWEFNIENAIKMSILSEKSAFESDKRIVNSEGSFLNSHTTINVFGNSLGVLEKYK 179

Query: 179 GTG-------------------SYSKSFRRLPKLESEIEGVREKALWEFEMSSKARKLEK 219
            T                     YS S R    ++ EI G +        + S  RK++ 
Sbjct: 180 STRYSNYTCMIAKDKNSMQRDFDYSLSRRIDDLIKPEILGQKTAKRAISRLGS--RKIQT 237

Query: 220 YNGEIILEPKAVASILSIFLPNVSARNVYLKRS-RFTELGIEVASGGLTIIDDPTVEGGI 278
               II   +      S     +S  NVY K +    +L +++    L I ++P ++ G+
Sbjct: 238 MRSPIIFSSEISHMFFSHLASAISGDNVYQKSTFLINDLKMKIFPDWLDIEENPHLKRGL 297

Query: 279 NSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGYSSQPSISPSNIM 338
            S  FD EG     K+IIK GIL ++L +      + + STGN   G      +S  NI 
Sbjct: 298 GSKPFDNEGVATEIKYIIKAGILQTWLLNCYNARKLKLDSTGNC--GGIHNWLVSNQNIS 355

Query: 339 ISPGNDEQDEGIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGGEIR-PFKGNMLVGNVFE 397
                 + D+GI +  + G+   + ++G++S    +G+ V  G+I  P     + GN+  
Sbjct: 356 FEELLKKMDQGILVTELMGQ-GVDIINGNYSRGA-VGFWVEKGKISYPINEITISGNLRN 413

Query: 398 MLKNVTNIGKEIE 410
           M  N+ +I  +++
Sbjct: 414 MWNNIVSISSDVD 426


>pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa (strain 9a5c)
           >gi|9106089|gb|AAF83937.1|AE003949_1 (AE003949) TldD
           protein [Xylella fastidiosa]
           Length = 485
           
 Score = 73.4 bits (177), Expect = 5e-12
 Identities = 46/163 (28%), Positives = 82/163 (50%), Gaps = 8/163 (4%)

Query: 257 LGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGI 316
           +G  VAS G+TI+DD T++G   S + D EG P     +I++G+L  ++ D     L+G+
Sbjct: 288 IGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPTQCTTLIEDGVLVGYMQDTLNARLMGV 347

Query: 317 GSTGNASR---GYSSQPSISPSNIMISPGNDEQDEGIFIRGIY----GEHTANSVSGDFS 369
            STGN  R    + + P ++ + +     + E+      +G+Y    G    +  SG + 
Sbjct: 348 ASTGNGRRESFAHLTMPRMTNTYMRAGVHSREEMIRSVKKGLYAVNFGGGQVDITSGKYV 407

Query: 370 LNVDLGYVVRGGEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEI 411
            +    Y++  G +  P KG  L+GN  E ++ V  IG ++ +
Sbjct: 408 FSATEAYLIEDGRVTAPIKGATLIGNGPETMQRVRMIGDDLAL 450


>sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C64186 pmbA protein -
           Haemophilus influenzae (strain Rd KW20)
           >gi|1574709|gb|AAC22807.1| (U32795) pmbA protein (pmbA)
           [Haemophilus influenzae Rd]
           Length = 451
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 93/400 (23%), Positives = 163/400 (40%), Gaps = 47/400 (11%)

Query: 39  RKVEVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYP 98
           R  E+E   F   G +G+ V    + G +  S S+ +   ++  V+ A  IAK       
Sbjct: 51  RLQEIENVEFTNDGALGISVYMGQQKGNA--STSDLSESAIKNAVEAALAIAKYTSP--- 105

Query: 99  GFPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTELVDVPPNAEASI-----GLSTSERGIM 153
                    +  GL D  +      ++  Y    +DV    E ++      L   ER I+
Sbjct: 106 --------DDCTGLADKDLMAFDAPDLELYHAADIDVDKATELALQAEQAALQADER-II 156

Query: 154 NSNGTEGREERTLLAFG-LYVFEKSKGTGSYSKSFRRLPKLESEIEGVRE---------- 202
           NSNG        +  +G  +   +S  +  YS S   +  +E  +E   E          
Sbjct: 157 NSNGASFNSHTGVKVYGNSHGMLQSYLSSRYSLSCSVIGGVEDALENDYEYTISREFDKL 216

Query: 203 -KALWEFEMSSKA-------RKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRF 254
              +W  E  +K        +KL      +I        I+S F   +S  ++Y K S  
Sbjct: 217 QSPIWVGENCAKKVVSRLNPQKLSTREVPVIFLNDVATGIISHFAAAISGGSLYRKSSFL 276

Query: 255 TE-LGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHL 313
            + LG +V     +I + P +   + S  FD EG     + I++ GIL ++L     G  
Sbjct: 277 LDHLGKQVLPDWFSISERPHLLRRLASTPFDSEGVRTQDREIVENGILQTYLVTSYSGKK 336

Query: 314 IGIGSTGNAS--RGYSSQPSISPSNIMISPGNDEQDEGIFIRGIYGEHTANSVSGDFSLN 371
           +G+ STG+A     +  +P+++     ++    +   G+ +  + G+   N V+GD+S  
Sbjct: 337 LGMSSTGHAGGIHNWLVKPNLTGG---LTALLRQMGTGLLVTDVMGQ-GVNIVTGDYSRG 392

Query: 372 VDLGYVVRGGEIR-PFKGNMLVGNVFEMLKNVTNIGKEIE 410
              G+ V  GEI+ P     + G + +MLKN+  +  +IE
Sbjct: 393 AS-GFWVENGEIQYPVAEITIAGQLQDMLKNMLAVADDIE 431


>sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||S13730 pmbA protein -
           Escherichia coli >gi|42440|emb|CAA38091.1| (X54152) pmbA
           is involved in the  production of antibiotic MccB17
           [Escherichia coli] >gi|537077|gb|AAA97132.1| (U14003)
           pmbA gene product [Escherichia coli]
           >gi|1732440|dbj|BAA07915.1| (D44452) TldE protein
           [Escherichia coli] >gi|1790682|gb|AAC77192.1| (AE000494)
           maturation of antibiotic MccB17, see tld genes
           [Escherichia coli K12]
           Length = 450
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 53/198 (26%), Positives = 94/198 (46%), Gaps = 6/198 (3%)

Query: 215 RKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTE-LGIEVASGGLTIIDDPT 273
           RKL      +I   +    +    +  ++  +VY K +   + LG ++    LTI + P 
Sbjct: 237 RKLSTMKAPVIFANEVATGLFGHLVGAIAGGSVYRKSTFLLDSLGKQILPDWLTIEEHPH 296

Query: 274 VEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGYSSQPSIS 333
           +  G+ S  FD EG    R+ IIK+GIL+ +L        +G+ STG+A  G      I+
Sbjct: 297 LLKGLASTPFDSEGVRTERRDIIKDGILTQWLLTSYSARKLGLKSTGHA--GGIHNWRIA 354

Query: 334 PSNIMISPGNDEQDEGIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGGEIR-PFKGNMLV 392
              +       E   G+ +  + G+   ++++GD+S     G+ V  GEI+ P     + 
Sbjct: 355 GQGLSFEQMLKEMGTGLVVTELMGQ-GVSAITGDYSRGA-AGFWVENGEIQYPVSEITIA 412

Query: 393 GNVFEMLKNVTNIGKEIE 410
           GN+ +M +N+  +G +IE
Sbjct: 413 GNLKDMWRNIVTVGNDIE 430


>pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aeruginosa  (strain
           PAO1) >gi|9950709|gb|AAG07860.1|AE004861_1 (AE004861)
           PmbA protein [Pseudomonas aeruginosa]
           Length = 449
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 64/269 (23%), Positives = 118/269 (43%), Gaps = 24/269 (8%)

Query: 154 NSNGTEGREERTLLAFGLYVFEKSKGT--GSYSKSFRRLPKLESEIEGVREKALWEFEMS 211
           NS+G  G    T  +    +  + +G     Y     R  +  +  E +  +A       
Sbjct: 173 NSHGFIGGYASTRHSLSCVMIAEGEGQMQRDYWYDVNRRGEALASAESIGRRAAERAASR 232

Query: 212 SKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTE--LGIEVASGGLTII 269
             AR ++     ++  P+    +   FL  +S  ++Y ++S F E  LG  +    L+I 
Sbjct: 233 LGARPVQTAEVPVLFAPEIAVGLFGHFLGAISGGSLY-RKSSFLEGALGQRLFPEWLSID 291

Query: 270 DDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGYSSQ 329
           + P + G + S SFD +G     K  ++ G L S++     G  +G+ ST NA       
Sbjct: 292 ERPHLVGALGSASFDSDGLATYAKPFVENGELVSYVLGTYSGRKLGLPSTANAG------ 345

Query: 330 PSISPSNIMISPGNDEQ-------DEGIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGGE 382
                 N+ +S G+++Q       + G+ +  + G+   N V+GD+S     GY V  GE
Sbjct: 346 ---GVHNLFVSHGDEDQAALIRRMERGLLVTELMGQ-GVNLVTGDYSRGA-AGYWVENGE 400

Query: 383 IR-PFKGNMLVGNVFEMLKNVTNIGKEIE 410
           I+ P +   +  N+ ++ + +  +GK+IE
Sbjct: 401 IQFPVQEVTIAANLRDLFRRIVAVGKDIE 429


>pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment)
           Length = 313
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 47/170 (27%), Positives = 79/170 (45%), Gaps = 9/170 (5%)

Query: 257 LGIEVASGGLTIIDDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGI 316
           +G +VA+ G+T++DD T+     S S D EG P  R  +I++GIL  ++ D++   L+ +
Sbjct: 115 MGRQVAAKGVTVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGILVGYMQDRQNARLMNM 174

Query: 317 GSTGN-ASRGYSSQPSISPSNIMISPGNDEQDEGIFI-------RGIYGEHTANSVSGDF 368
             TGN A+R Y+  P    +N  +  G      G+         R  +G    +  SG +
Sbjct: 175 KPTGNAAARRYAHVPMPRMTNTYMLRGRSRSGRGVLASVKNAASRANFGGGQVDITSGKY 234

Query: 369 SLNVDLGYVVRGGEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEILDGFAS 417
                  Y    G+   P +G ML+GN    L  +  IG ++ +  G  +
Sbjct: 235 VSQCTEAYKSENGKSGGPAEGRMLIGNGPTDLHRIRMIGNDLALDTGIGT 284


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.315    0.137    0.383 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 163390276
Number of Sequences: 2977
Number of extensions: 7309949
Number of successful extensions: 12846
Number of sequences better than 1.0e-10: 41
Number of HSP's better than  0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 12768
Number of HSP's gapped (non-prelim): 53
length of query: 427
length of database: 189,106,746
effective HSP length: 59
effective length of query: 368
effective length of database: 153,796,013
effective search space: 56596932784
effective search space used: 56596932784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (21.9 bits)
S2: 166 (69.1 bits)