BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0184 (PAB0184) DE:PROBABLE MONOOXYGENASE (407 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||C75218 probable monooxygenase PAB0184 - Pyrococcus abyssi (... 806 0.0 pir||F72254 hypothetical protein TM1433 - Thermotoga maritima (s... 328 5e-89 pir||C75144 sarcosine oxidase, chain alpha (soxa) PAB0212 - Pyro... 190 2e-47 pir||H71183 probable D-nopaline dehydrogenase - Pyrococcus horik... 183 3e-45 gi|11497889 sarcosine oxidase, subunit alpha (soxA) [Archaeoglob... 173 4e-42 emb|CAB88983.1| (AL353864) putative oxidoreductase. [Streptomyce... 142 8e-33 pir||A83461 hypothetical protein PA1488 [imported] - Pseudomonas... 125 7e-28 pir||D71016 probable thioredoxin reductase - Pyrococcus horikosh... 94 2e-18 sp|O18480|DLHD_MANSE DIHYDROLIPOAMIDE DEHYDROGENASE (E3) >gi|226... 94 3e-18 pir||D75116 thioredoxin reductase (trxb) PAB0500 - Pyrococcus ab... 92 8e-18 pir||B82969 sarcosine oxidase alpha subunit PA5418 [imported] - ... 91 2e-17 pir||H72322 thioredoxin reductase - Thermotoga maritima (strain ... 87 4e-16 pir||D83627 alkyl hydroperoxide reductase subunit F PA0140 [impo... 85 1e-15 emb|CAC11966.1| (AL445065) NADH peroxidase related protein [Ther... 83 7e-15 sp|P80880|TRXB_BACSU THIOREDOXIN REDUCTASE (TRXR) (GENERAL STRES... 82 1e-14 pir||T34868 probable glutamate synthase small chain - Streptomyc... 82 1e-14 emb|CAC12113.1| (AL445066) probable thioredoxin reductase [Therm... 80 5e-14 sp|O32823|TRXB_LISMO THIOREDOXIN REDUCTASE (TRXR) >gi|2246749|gb... 79 1e-13 pir||F72705 probable thioredoxin reductase APE1061 - Aeropyrum p... 78 2e-13 dbj|BAB07290.1| (AP001519) thioredoxin reductase (NADPH) [Bacill... 78 2e-13 gi|11499149 thioredoxin reductase (trxB) [Archaeoglobus fulgidus... 78 2e-13 gi|11498012 NADH oxidase (noxA-3) [Archaeoglobus fulgidus] >gi|7... 77 3e-13 emb|CAA11554.1| (AJ223804) 2-oxoglutarate dehydrogenase, E3 subu... 77 4e-13 pir||B75551 glutamate synthase, small subunit - Deinococcus radi... 77 4e-13 gb|AAF34796.1|AF228640_1 (AF228640) lipoamide dehydrogenase prec... 77 4e-13 sp|O06465|AHPF_XANCH ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi... 76 7e-13 pir||B75024 glutamate synthase small chain. PAB1214 - Pyrococcus... 76 9e-13 emb|CAB60740.1| (Y18636) thioredoxine reductase [Staphylococcus ... 76 9e-13 pir||F82936 thioredoxin reductase UU074 [imported] - Ureaplasma ... 75 1e-12 pir||H82668 subunit F of alkyl hydroperoxide reductase XF1531 [i... 75 1e-12 gb|AAG17888.1| (AF295339) dihydrolipoamide dehydrogenase precurs... 75 2e-12 pir||G70655 probable small subunit of NADH-dependent glutamate s... 74 3e-12 sp|O05204|AHPF_STAAU ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi... 74 3e-12 pir||D71076 probable glutamate synthase small chain - Pyrococcus... 74 3e-12 sp|P09832|GLTD_ECOLI GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN (GLU... 74 3e-12 dbj|BAA21091.1| (D86223) glutamate synthase [Pyrococcus sp.] 73 5e-12 gi|11497870 NADH oxidase (noxA-1) [Archaeoglobus fulgidus] >gi|7... 73 5e-12 dbj|BAB05342.1| (AP001512) unknown conserved protein [Bacillus h... 73 5e-12 pir||A49911 NADH oxidase (hydrogen peroxide-forming) (EC 1.6.-.-... 73 6e-12 sp|O82864|AHPF_PSEPU ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi... 73 6e-12 pir||H75052 NADH oxidase (noxa-1) PAB0936 - Pyrococcus abyssi (s... 73 6e-12 pir||G64491 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Methano... 72 1e-11 gi|4557525 dihydrolipoamide dehydrogenase precursor; E3 componen... 72 1e-11 gb|AAB01381.1| (L13761) dihydrolipoamide dehydrogenase [Homo sap... 72 1e-11 emb|CAB57297.1| (AJ243598) NADH oxidase [Sulfolobus solfataricus] 72 1e-11 gb|AAF21029.1|AF208523_2 (AF208523) HcnB [Pseudomonas aeruginosa] 72 1e-11 gb|AAF34795.1|AF228639_1 (AF228639) lipoamide dehydrogenase prec... 72 1e-11 gb|AAF79529.1|AC023673_17 (AC023673) F21D18.28 [Arabidopsis thal... 72 1e-11 pir||G83370 hydrogen cyanide synthase HcnB PA2194 [imported] - P... 72 1e-11 gb|AAG21579.1|AC051631_2 (AC051631) lipoamide dehydrogenase, put... 72 1e-11 sp|P09623|DLDH_PIG DIHYDROLIPOAMIDE DEHYDROGENASE, MITOCHONDRIAL... 71 2e-11 gb|AAA35764.1| (J03620) dihydrolipoamide dehydrogenase precursor... 71 2e-11 pir||E69194 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Methano... 71 2e-11 pir||H71171 probable NADH oxidase - Pyrococcus horikoshii >gi|32... 71 2e-11 sp|P50970|DLDH_ZYMMO DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONEN... 71 2e-11 gi|11498007 NADH oxidase (noxA-2) [Archaeoglobus fulgidus] >gi|7... 71 2e-11 emb|CAA11546.1| (AJ223781) thioredoxin reductase [Staphylococcus... 71 2e-11 pir||D72382 hypothetical protein TM0395 - Thermotoga maritima (s... 71 2e-11 gb|AAD52148.1|AF129406_2 (AF129406) alkyl hydroperoxide reductas... 71 2e-11 gb|AAK42391.1| Thioredoxin reductase (trxB-1) [Sulfolobus solfat... 71 3e-11 pir||D71200 probable glutamate synthase small chain - Pyrococcus... 71 3e-11 sp|P75531|TRXB_MYCPN THIOREDOXIN REDUCTASE (TRXR) >gi|2146661|pi... 70 5e-11 pir||D35156 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Eubacte... 70 5e-11 gb|AAK42805.1| Mercuric reductase (Hg(II) reductase) (merA) [Sul... 70 5e-11 gb|AAA19188.1| (U10552) acetoin dehydrogenase [Klebsiella pneumo... 70 5e-11 pir||JC4793 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Klebsi... 70 5e-11 sp|P50971|TRXB_EUBAC THIOREDOXIN REDUCTASE (TRXR) >gi|1353197|gb... 70 5e-11 sp|O66790|TRXB_AQUAE THIOREDOXIN REDUCTASE (TRXR) >gi|7427756|pi... 69 7e-11 pir||T06332 ferric leghemoglobin reductase isoenzyme 2 precursor... 69 9e-11 >pir||C75218 probable monooxygenase PAB0184 - Pyrococcus abyssi (strain Orsay) >gi|5457703|emb|CAB49194.1| (AJ248283) PROBABLE MONOOXYGENASE [Pyrococcus abyssi] Length = 407 Score = 806 bits (2059), Expect = 0.0 Identities = 407/407 (100%), Positives = 407/407 (100%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP Sbjct: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60 Query: 61 EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120 EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH Sbjct: 61 EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120 Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA Sbjct: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180 Query: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF 240 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF Sbjct: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF 240 Query: 241 WVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLV 300 WVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLV Sbjct: 241 WVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLV 300 Query: 301 DYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIKGENVRFVVPHYLSGDRDVWIYLRVSRP 360 DYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIKGENVRFVVPHYLSGDRDVWIYLRVSRP Sbjct: 301 DYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIKGENVRFVVPHYLSGDRDVWIYLRVSRP 360 Query: 361 MEDVRLEMPEIGKRMRLPIVKPSEMIRIKLRGKDVKGVDKITVRVVK 407 MEDVRLEMPEIGKRMRLPIVKPSEMIRIKLRGKDVKGVDKITVRVVK Sbjct: 361 MEDVRLEMPEIGKRMRLPIVKPSEMIRIKLRGKDVKGVDKITVRVVK 407 >pir||F72254 hypothetical protein TM1433 - Thermotoga maritima (strain MSB8) >gi|4981998|gb|AAD36503.1|AE001795_6 (AE001795) oxidoreductase, putative [Thermotoga maritima] Length = 403 Score = 328 bits (833), Expect = 5e-89 Identities = 184/406 (45%), Positives = 263/406 (64%), Gaps = 13/406 (3%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62 DV VIG G AGMAAA+KA+E G V+L++ ++ GGIL QCIH GFG+HYF++ELTGPE+ Sbjct: 4 DVMVIGAGAAGMAAALKAKEEGAEVLLVERDERTGGILNQCIHNGFGLHYFRQELTGPEY 63 Query: 63 AYKLMNRLRDVEVR--TSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120 A + ++ + +R T+A V + ++R+ +++ GIEE+ ++YA GARER Sbjct: 64 AERFQEKMEKMGIRALTNAYVKRVE-----DRRVILVTEQGIEEVEVGALVYATGARERP 118 Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180 + I GDR +GIFTAG AQ L++I +PG+ LI+GSGD+GLIMARR LEG V Sbjct: 119 FGSLMIPGDRPSGIFTAGVAQRLINIENRLPGKRALILGSGDIGLIMARRLTLEGMEVVG 178 Query: 181 VIELMPYPGGLARNVM-ILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239 V+E +PY GGL RNV+ L D+NIPLYLS VVE+RG+ R++ V + KVDE R IP TE Sbjct: 179 VVERLPYAGGLLRNVIQCLEDYNIPLYLSSTVVEVRGRERLEEVVVAKVDEQFRPIPRTE 238 Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDL 299 VDT+++S GLIP V+L+ + V +P++ G V++ +T+ IF AGN VI DL Sbjct: 239 RVFKVDTLVLSVGLIPQVELIENL-VVKNPTSRGVGVSNIGQTSRDWIFSAGNCTVIFDL 297 Query: 300 VDYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIKGENVRFVVPHYLSGDRDVWIYLRVSR 359 VDYV +GE A A +F+ + R + R G+NV V P + + + +YLRV + Sbjct: 298 VDYVSYEGETAGRYAAKFVKGEIPREKIPVR--PGKNVMVVHPIWYTPAEPLTLYLRVKK 355 Query: 360 PMEDVRLEMPEIGKRMRLPIVKPSEMIRIKLRGKDVKGVDKITVRV 405 PME RL + + + PSEM+R+K+ +D++G+D+I V V Sbjct: 356 PMEKGRLVVGRFAREFE--DLVPSEMLRVKISDRDLEGLDEIVVSV 399 >pir||C75144 sarcosine oxidase, chain alpha (soxa) PAB0212 - Pyrococcus abyssi (strain Orsay) >gi|5457744|emb|CAB49234.1| (AJ248284) sarcosine oxidase, subunit alpha (soxA) [Pyrococcus abyssi] Length = 481 Score = 190 bits (479), Expect = 2e-47 Identities = 119/318 (37%), Positives = 177/318 (55%), Gaps = 10/318 (3%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62 D+ VIGGGPAGM AAI A + G V+LIDEN LGG L + H FG + G + Sbjct: 121 DIIVIGGGPAGMMAAISAHDAGAKVVLIDENPMLGGQLVKQTHKFFGKRSQFAGVRGVKI 180 Query: 63 AYKLMNRL--RDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120 A L N + R++EV V I + + + + S + E+ + II A GA E+ Sbjct: 181 AEILENEVKKRNIEVFLQTSAVGIFQDGNEKIVVGIRKESELIELHGRAIIVATGAMEK- 239 Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180 + + + GI+ AG QTLM+ YG+ PG + LIVG+G+VGLI+A + G +V+A Sbjct: 240 --SVPFENNDLPGIYGAGAIQTLMNTYGVKPGEKALIVGAGNVGLILAYQLIQAGVKVEA 297 Query: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF 240 ++E MP GG + + +P+ H ++ GK +V+R + ++DEN R IPGTE Sbjct: 298 IVEAMPKIGGYFVHAAKVRRLGVPILTRHTILRAEGKEKVERAIVAQIDENWRPIPGTEK 357 Query: 241 WVDVDTVIISAGLIPNVKLLTKVGVAID--PSTGGPIV--NDRLETTVPGIFVAGNALVI 296 DVD + I+ GL P+++LL + G I GG + ++ LETTV GIFVAG+ I Sbjct: 358 IFDVDLIAIAVGLRPSIELLQQAGCQIRYVRELGGHVAVRDEWLETTVRGIFVAGDTAGI 417 Query: 297 NDLVDYVVEQGELAAEGA 314 + ++E G++A A Sbjct: 418 EEATTAMLE-GKIAGIAA 434 >pir||H71183 probable D-nopaline dehydrogenase - Pyrococcus horikoshii >gi|3258180|dbj|BAA30863.1| (AP000007) 482aa long hypothetical D-nopaline dehydrogenase [Pyrococcus horikoshii] Length = 482 Score = 183 bits (460), Expect = 3e-45 Identities = 122/338 (36%), Positives = 185/338 (54%), Gaps = 14/338 (4%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62 D+ V+GGGPAGM AAI A + G VILIDE+ LGG L + H FG + G + Sbjct: 122 DIIVVGGGPAGMMAAISASDTGAKVILIDESPMLGGQLVKQTHKFFGKRDQFAGIRGIKI 181 Query: 63 AYKLMNRLRDVE-VRTSARVVEIINYSDIEKRLK--VISPSGIEEIRAKTIIYAAGARER 119 A L + E ++ R + + D E++L V + + E + K +I A GA E+ Sbjct: 182 AEILRREIEKRENIKAYLRTSAVGIFQDGEEKLVIGVRKENELIEFKGKAVIVATGAMEK 241 Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179 I + + GI+ AG QTLM+ YGI PG + LIVG+G+VGLI+A + +V+ Sbjct: 242 ---TIPFENNDLPGIYGAGAIQTLMNTYGIKPGEKALIVGAGNVGLILAYQLLQANVQVQ 298 Query: 180 AVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239 A++E MP GG + + +P+ H +++ G+ +V+R + ++DEN IPGTE Sbjct: 299 AIVEAMPKIGGYFVHAAKVRRLGVPILTRHTILKAEGEEKVERAIVAEIDENWNPIPGTE 358 Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAID--PSTGGPI-VNDR-LETTVPGIFVAGNALV 295 DVD + I+ GL P+++LL + G I GG + V DR +ETTV GIFVAG+ Sbjct: 359 KIFDVDLIAIAVGLRPSIELLQQAGCQIKYVRELGGHVPVRDRWMETTVKGIFVAGDTAG 418 Query: 296 INDLVDYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIK 333 I + ++E G++A A + GI +W + I+ Sbjct: 419 IEEATTAMLE-GKIAGLAAALRL---GIAGEEWVKEIE 452 >gi|11497889 sarcosine oxidase, subunit alpha (soxA) [Archaeoglobus fulgidus] >gi|7482953|pir||A69284 coenzyme F420--quinone oxidoreductase (EC 1.6.5.-) 56K chain - Archaeoglobus fulgidus >gi|2650363|gb|AAB90959.1| (AE001086) sarcosine oxidase, subunit alpha (soxA) [Archaeoglobus fulgidus] Length = 534 Score = 173 bits (433), Expect = 4e-42 Identities = 115/332 (34%), Positives = 174/332 (51%), Gaps = 11/332 (3%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62 DV VIGGGP GM+AAI A + G V+L+DEN +LGG L + H FG + G + Sbjct: 171 DVLVIGGGPGGMSAAINAGKYGAKVLLVDENPFLGGQLVKQTHRFFGSAKERAGTRGIKI 230 Query: 63 AYKL---MNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119 A L +N + +VEVR RV I N + + I+AK I+ A GA ER Sbjct: 231 AGILEEELNSIENVEVRRETRVFGIYNGEAGAYQRLNDDEGKLLRIKAKKIVVATGAYER 290 Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179 + + G++ AG QTLM++YGI PG LIVGSG+VGLI+ + G V Sbjct: 291 TLI---FENNDLPGVYGAGGVQTLMNVYGIKPGNMGLIVGSGNVGLILTYQLMQAGVNVA 347 Query: 180 AVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239 A++E MP GG + + +P+Y+ H +++ G+ V+ I ++D+ + IPGTE Sbjct: 348 AIVEAMPRIGGYFVHAAKVRRLGVPIYVRHTILKAIGRKSVEGAVIAQLDDRWQPIPGTE 407 Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAID--PSTGG--PIVNDRLETTVPGIFVAGNALV 295 + D + ++ GL P +LL + G + P GG P+ ET+V G++VAG+ Sbjct: 408 KEIKCDFICVAVGLSPTHELLYQAGCEMKFVPELGGIVPLRTRFNETSVKGLYVAGDVAG 467 Query: 296 INDLVDYVVEQGELAAEGAKEFIDNDGIRSRK 327 I + ++E G +A A + G ++K Sbjct: 468 IEEATAAIME-GRIAGIHAAVTLGYGGEEAKK 498 >emb|CAB88983.1| (AL353864) putative oxidoreductase. [Streptomyces coelicolor A3(2)] Length = 416 Score = 142 bits (354), Expect = 8e-33 Identities = 111/401 (27%), Positives = 175/401 (42%), Gaps = 25/401 (6%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62 DV V+G GPAG+ AA + G V+L++ GG+ C H GFG LTGP Sbjct: 7 DVLVVGAGPAGLTAAARLARTGARVVLLEREQSPGGVPRHCAHRGFGDR--PHALTGPAH 64 Query: 63 AYKLMNRLRDVEVRTSARVVEIINYSDIE--KRLKVISPSGIEEIRAKTIIYAAGARERH 120 A L D R A + + D + L + P G E + A+ ++ A GARER Sbjct: 65 A----RLLADAAARAGADLRTGVTALDWAGPRALTTVGPRGAETLAARAVVLATGARERP 120 Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180 + G R AG++T GE Q + +YG G +IVG+ V A GA V A Sbjct: 121 RAARLVPGTRPAGVYTTGELQQAVHLYGQHIGTRAVIVGAEGVSHAAADTVRAAGADVLA 180 Query: 181 VI-ELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239 ++ EL P A + P+ KV E+ G+GR+ V++ R G Sbjct: 181 LVTELPQAPAAPAWALAARLRHRTPVLTGTKVTELLGRGRLSGVRV-------RHRDGRS 233 Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDL 299 + DTV+ + +P+ +L + + +DP T GP V+ L T+ PG+F G+ L + Sbjct: 234 TVLACDTVVFTGDFVPDHELARRGALTLDPGTRGPAVDGALRTSRPGVFAVGSVLHAVES 293 Query: 300 VDYVVEQGELAAEGAKEFI-DNDGIRSRKW---TRLIKGENVRFVVPHYLSGDRDVWIYL 355 +G AA + ++ D W L+ G + + P+ ++ D + L Sbjct: 294 AATAAREGAHAATAVRRWLQDGTDPGDPYWPGGVPLLAGPPLLRIAPNRVTPDDRLPYLL 353 Query: 356 RVSRPMEDVRLEMPEIGK-----RMRLPIVKPSEMIRIKLR 391 R + P+ L + + G+ R L P +++ R Sbjct: 354 RTAVPLSHPALYVTQDGRPLHRERFHLGTAVPHRPLKLTAR 394 >pir||A83461 hypothetical protein PA1488 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9947442|gb|AAG04877.1|AE004577_12 (AE004577) hypothetical protein [Pseudomonas aeruginosa] Length = 412 Score = 125 bits (312), Expect = 7e-28 Identities = 86/295 (29%), Positives = 140/295 (47%), Gaps = 14/295 (4%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDEND-YLGGILPQCIHPGFGIHYFKEELTGPE 61 DVA++G GPAG+AAAI+ R G++ + + E D GGI C HP FG+ LTGP Sbjct: 8 DVAIVGSGPAGLAAAIELRRQGVARVCVLERDGEAGGIPRHCAHPPFGLREHGRLLTGPA 67 Query: 62 FAYKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119 +A + + + V++R VV + L++ +P G +RA ++ A GARE Sbjct: 68 YAQRNVEQAERAGVDIRLRHSVVALAAAG----LLQLATPEGPRSLRATRVLLATGARET 123 Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179 + GDR G+ G Q + + G+ P LIVG+ V L G R Sbjct: 124 PRSARLLGGDRPLGVINTGALQAYLYLQGLKPFERPLIVGTELVSLSAVMSCRRAGIRPV 183 Query: 180 AVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239 A++E + +P++ S +++EI G+GRV+ ++ D + I Sbjct: 184 AMLERNARATARWPLSLFPRLCGVPMHFSSELLEIEGRGRVEAARVRLGDGRVERIA--- 240 Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNAL 294 D +++S +P L+ + +DP++GGP ++ + P F AGN L Sbjct: 241 ----CDGILLSGRFVPESSLVRLSHLELDPASGGPRIDQFGRCSDPAYFAAGNLL 291 >pir||D71016 probable thioredoxin reductase - Pyrococcus horikoshii >gi|3257849|dbj|BAA30532.1| (AP000006) 336aa long hypothetical thioredoxin reductase [Pyrococcus horikoshii] Length = 336 Score = 94.4 bits (231), Expect = 2e-18 Identities = 100/337 (29%), Positives = 153/337 (44%), Gaps = 47/337 (13%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGG--ILPQCI--HPGFGIHYFKEE 56 ++DV +IG GPAG AAI A GL I+I ++ LGG + I +PGF E Sbjct: 23 VWDVIIIGAGPAGYTAAIYAARFGLDTIIITKD--LGGNMAITDLIENYPGF-----PEG 75 Query: 57 LTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLK------VISPSGIEEIRAKTI 110 ++G E + K+ ++++ V + E+I E V+ + +E +AKTI Sbjct: 76 ISGSELSKKMYDQVKKYGVEVI--IDEVIRIDPAECAYYEGPCNFVVKTANGKEYKAKTI 133 Query: 111 IYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYG-IMPGREILIVGSGDVGLIMAR 169 I A GA R ++ + G++ FT G + G+E+++VG G+ L A Sbjct: 134 IIAVGAEPR---KLNVPGEKE---FTGRGVSYCATCDGPLFVGKEVIVVGGGNTALQEAL 187 Query: 170 RFALEGARVKAVIELMPYPGGLARNVMILND----FNIPLYLSHKVVEIRGKGRVQRV-- 223 G +V V + R IL D IP L+ V EI+G +V+ V Sbjct: 188 YLHSIGVKVTLVHRRDKF-----RADKILQDRFKQAGIPAILNTVVTEIKGTNKVESVVL 242 Query: 224 KIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETT 283 K VK E + + VD V I G P + +G+ + G V+ + T Sbjct: 243 KNVKTGETVEK--------KVDGVFIFIGYEPKTDFVKHLGITDE--YGYIPVDMYMRTK 292 Query: 284 VPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFIDN 320 VPGIF AG+ + + V QG +AA AKEFI++ Sbjct: 293 VPGIFAAGDITNVFKQIAVAVGQGAIAANSAKEFIES 329 >sp|O18480|DLHD_MANSE DIHYDROLIPOAMIDE DEHYDROGENASE (E3) >gi|2267131|gb|AAB88282.1| (AF008586) dihydrolipoamide dehydrogenase [Manduca sexta] Length = 497 Score = 94.0 bits (230), Expect = 3e-18 Identities = 96/351 (27%), Positives = 164/351 (46%), Gaps = 54/351 (15%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------------- 47 D+ VIG GP G AAIKA +LG+ V+ +++ LGG C++ G Sbjct: 32 DLVVIGAGPGGYVAAIKAAQLGMKVVSVEKEPSLGG---TCLNVGCIPSKALLHNTHLYH 88 Query: 48 FGIHYFKE---ELTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLK----VISPS 100 H FK E +F +K M + V+ + ++ + K ++ +++P+ Sbjct: 89 MAKHDFKHRGIETGEVKFNFKAMMDYKVNAVKALTGGIAMLFQKNKVKLVRGAGTIVAPN 148 Query: 101 --------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPG 152 G+E + K I+ A G+ E F G+T D I T+ A +L + Sbjct: 149 KVEVKGEKGVETVNTKNILIATGS-EVTPFP-GVTFDE-KQIITSTGALSLESV-----P 200 Query: 153 REILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNI------PLY 206 +++L++G+G +GL + + GA V A IE + GG+ ++ + D+ I Sbjct: 201 KKMLVIGAGVIGLELGSVYQRLGADVTA-IEFLGSIGGIGIDMEVSKDYRILAKQGMKFK 259 Query: 207 LSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTKVG 264 L KV+ ++ +G +V+ V ++ G + +D D V+IS G P K L KVG Sbjct: 260 LETKVLGVKKEGSTVKVEDVSIE---GAKGGNKETMDCDVVLISIGRRPYTKDLGLDKVG 316 Query: 265 VAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAK 315 +A+D G VN++ +TTVPGI+ G+ + L ++G + EG K Sbjct: 317 IALD-DRGRVPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK 366 >pir||D75116 thioredoxin reductase (trxb) PAB0500 - Pyrococcus abyssi (strain Orsay) >gi|5458156|emb|CAB49645.1| (AJ248285) thioredoxin reductase (trxB) [Pyrococcus abyssi] Length = 345 Score = 92.4 bits (226), Expect = 8e-18 Identities = 100/334 (29%), Positives = 151/334 (44%), Gaps = 41/334 (12%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGG--ILPQCI--HPGFGIHYFKEE 56 ++DV +IG GPAG AAI A GL I+I ++ LGG + I +PGF E Sbjct: 32 VWDVIIIGAGPAGYTAAIYAARFGLDTIIITKD--LGGNMAITDLIENYPGF-----PEG 84 Query: 57 LTGPEFAYKLMNRLRDVEVRTSARVVEIIN-----YSDIEKRLKVISPSGIEEIRAKTII 111 ++G E A ++ ++ V V I+ Y + + +V + +G +E + KTII Sbjct: 85 ISGSELAKRMYEHVKKYGVDVIFDEVVRIDPAECAYYEGPCQFEVKTANG-KEYKGKTII 143 Query: 112 YAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYG-IMPGREILIVGSGDVGLIMARR 170 A GA R ++ + G++ FT G + G+E+++VG G+ L A Sbjct: 144 IAVGAEPR---KLHVPGEKE---FTGRGVSYCATCDGPLFVGKEVIVVGGGNTALQEALY 197 Query: 171 FALEGARVKAVIELMPYPGGLARNVMILND----FNIPLYLSHKVVEIRGKGRVQRVKIV 226 G +V V + R IL D IP L+ V EIRG +V+ V + Sbjct: 198 LHSIGVKVTLVHRRDKF-----RADKILQDRLKQAGIPTILNTVVTEIRGTNKVESVVLK 252 Query: 227 KVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPG 286 V G F VD V I G P + +G+ + G V+ + T VPG Sbjct: 253 NVKT------GETFEKKVDGVFIFIGYEPKTDFVKHLGITDE--YGYIKVDMYMRTKVPG 304 Query: 287 IFVAGNALVINDLVDYVVEQGELAAEGAKEFIDN 320 IF AG+ + + V QG +AA AKEFI++ Sbjct: 305 IFAAGDITNVFKQIAVAVGQGAIAANSAKEFIES 338 >pir||B82969 sarcosine oxidase alpha subunit PA5418 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951745|gb|AAG08803.1|AE004954_5 (AE004954) sarcosine oxidase alpha subunit [Pseudomonas aeruginosa] Length = 1005 Score = 91.3 bits (223), Expect = 2e-17 Identities = 81/301 (26%), Positives = 130/301 (42%), Gaps = 40/301 (13%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62 DV V+G GPAG+AAA+ A G VIL DE + GG L +E L G Sbjct: 172 DVLVVGAGPAGLAAALAAARSGARVILADEQEEFGGSLLDT----------RETLDGKPA 221 Query: 63 AYKLMNRLRDVE--------VRTSARVVEIINYSDIEKR----LKVISPSG-----IEEI 105 A + + + +++ R++ N+ I +R L ++P G + + Sbjct: 222 AEWVADAVAELQGLPEVILLPRSTVNGYHDHNFLTIHERRTDHLGEVAPLGQVRQRVHRV 281 Query: 106 RAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGL 165 RAK ++ AAGA ER + + + G AG T + YG+ PG+++++ + D Sbjct: 282 RAKRVVLAAGAHER---PLVYGNNDLPGNMLAGAVSTYVRRYGVAPGKKLVLATNNDYAY 338 Query: 166 IMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKI 225 +A + G +V A+ + P G V + + V+E RG RV K+ Sbjct: 339 RVALDWQEAGLQVVAIADARANPRG--EWVEEARQRGMRVITGSSVIEARGGKRVSGAKV 396 Query: 226 VKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVP 285 ++D G E W+D D + S G P V L + +G G P + + VP Sbjct: 397 ARIDLQAMRASGGE-WLDCDLIASSGGYSPVVHLASHLG-------GKPEWREEILAFVP 448 Query: 286 G 286 G Sbjct: 449 G 449 >pir||H72322 thioredoxin reductase - Thermotoga maritima (strain MSB8) >gi|4981404|gb|AAD35951.1|AE001753_7 (AE001753) thioredoxin reductase [Thermotoga maritima] Length = 317 Score = 87.0 bits (212), Expect = 4e-16 Identities = 88/318 (27%), Positives = 146/318 (45%), Gaps = 28/318 (8%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILID---ENDYLGGILPQCIHPGFGIHYFKEELT 58 YD+ V+GGGPAG+ +AI AR GLSV++++ E Y+ +PGF ++ Sbjct: 18 YDIVVVGGGPAGLTSAIYARRAGLSVLVVEKAIEGGYVNLTHLVENYPGF------PAIS 71 Query: 59 GPEFAYKLMNRLRDVEVRT-SARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117 G E A K +A VV++ +++ KV+ + I A +I A GA Sbjct: 72 GEELASKFKEHAEKFGADIYNAEVVKL----EVQGDKKVVELDDGKRIEAPVVIVATGAN 127 Query: 118 ERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177 + ++ + G++ F G + + G+++++VG GD + + + Sbjct: 128 PK---KLNVPGEK--EFFGKGVSYCATCDGYLFAGKDVIVVGGGDSACDESIFLSNIVNK 182 Query: 178 VKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPG 237 + + L +LN+ I + + V EIRGK +V+ V I EN++ G Sbjct: 183 ITMIQLLETLTAAKVLQERVLNNPKIEVIYNSTVREIRGKDKVEEVVI----ENVK--TG 236 Query: 238 TEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVIN 297 + D V I GL PN KLL + V +DP G I ++ +ET+V GI+ G+ N Sbjct: 237 ETKVLKADGVFIFIGLDPNSKLLEGL-VELDP-YGYVITDENMETSVKGIYAVGDVRKKN 294 Query: 298 -DLVDYVVEQGELAAEGA 314 + V G +A E A Sbjct: 295 LRQIVTAVADGAIAVEHA 312 >pir||D83627 alkyl hydroperoxide reductase subunit F PA0140 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9945970|gb|AAG03530.1|AE004452_2 (AE004452) alkyl hydroperoxide reductase subunit F [Pseudomonas aeruginosa] Length = 521 Score = 85.0 bits (207), Expect = 1e-15 Identities = 81/304 (26%), Positives = 144/304 (46%), Gaps = 33/304 (10%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 +DV V+GGGPAG AAAI A G+ + E + G +L F +E GP+ Sbjct: 212 FDVLVVGGGPAGAAAAIYAARKGIRTGVAAER-FGGQVLDTMAIENF---ISVQETEGPK 267 Query: 62 FAYKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119 A L +R +V++ R +++ + + +V SG ++AKT+I A GAR R Sbjct: 268 LARALEEHVRHYEVDIMNLQRASKLVPAKNAGELHEVRFESG-GSLKAKTLILATGARWR 326 Query: 120 HAFEIGITGD---RVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176 E+G+ G+ + G+ + G+ + ++G G+ G+ A++ A Sbjct: 327 ---EMGVPGEQEYKAKGVCFCPHCDG-----PLFKGKRVAVIGGGNSGV----EAAIDLA 374 Query: 177 RVKAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENL 232 + A + L+ + L + ++ N+ + S E++G G+ + +V D N Sbjct: 375 GIVAHVTLLEFDSKLRADAVLQRKLYSLPNVEVITSALTSEVKGDGQ-KVTGLVYKDRNS 433 Query: 233 REIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292 E ++++ + + GL+PN + L K V + P G IV+ R ET++PGIF AG+ Sbjct: 434 EEFKS----IELEGIFVQIGLLPNTEWL-KGSVELSP-RGEIIVDARGETSLPGIFAAGD 487 Query: 293 ALVI 296 + Sbjct: 488 VTTV 491 >emb|CAC11966.1| (AL445065) NADH peroxidase related protein [Thermoplasma acidophilum] Length = 435 Score = 82.7 bits (201), Expect = 7e-15 Identities = 81/309 (26%), Positives = 147/309 (47%), Gaps = 42/309 (13%) Query: 3 DVAVIGGGPAGMAAAIKARELG--LSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60 D+ VIGGG AGMAAA KA+ + +V +I+ ++ +C GI YF + + G Sbjct: 2 DIVVIGGGAAGMAAASKAKRVNKDANVTVIESGSFVS--YAEC-----GIPYFLQGIVGK 54 Query: 61 EFAYKLMNRLRDVEVRTSARVVEIINYSDIEK----RLKVISPSGIEEIRAKTIIYAAGA 116 A L++ +E T R +++I ++K L ++ +G ++ +I A G+ Sbjct: 55 --AEDLLH--YPLEEFTEKRGIKVITGRVVKKIDTASLSLVLDNG-SAVKFDRLIIATGS 109 Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPG-REILIVGSGDVGLIMARRFALEG 175 R R I +G+F ++ + + + G R I I+G+G +G+ +A G Sbjct: 110 RPR------IPDGIASGVFGLRSLESAIRLKEAIDGSRTITIIGAGVLGVELASTLTEAG 163 Query: 176 ARVKAVIELMPYPGGLARNV-MILNDF---NIPLYLSHKVVEIRGKGRVQRVKIVKVDEN 231 RVK + + L ++ ILND+ + + S VEI+ KG VD++ Sbjct: 164 KRVKVISKYDRVMPQLDPDMGKILNDYFSSKVEVEFSSTPVEIK-KGEDGFAVKTTVDDH 222 Query: 232 LREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAG 291 + D VI + G++PN + G+ +D G I ++ +ET++PGI+ AG Sbjct: 223 VS-----------DVVIAAVGIVPNSNIAVDAGIKVD-QRGAIITDEHMETSIPGIYAAG 270 Query: 292 NALVINDLV 300 + + +++ Sbjct: 271 DVATVKNII 279 >sp|P80880|TRXB_BACSU THIOREDOXIN REDUCTASE (TRXR) (GENERAL STRESS PROTEIN 35) (GSP35) >gi|7427754|pir||A69727 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Bacillus subtilis >gi|1945648|emb|CAB08055.1| (Z94043) hypothetical protein [Bacillus subtilis] >gi|2635992|emb|CAB15484.1| (Z99121) thioredoxin reductase [Bacillus subtilis] Length = 316 Score = 81.9 bits (199), Expect = 1e-14 Identities = 89/333 (26%), Positives = 151/333 (44%), Gaps = 46/333 (13%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQC----IHPGFGIHYFKEE 56 +YDV +IG GPAGM AA+ LS ++I E GG + +PGF E Sbjct: 6 IYDVIIIGAGPAGMTAAVYTSRANLSTLMI-ERGIPGGQMANTEDVENYPGF------ES 58 Query: 57 LTGPEFAYKLMNRLRDVEVRTS-ARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAG 115 + GPE + K+ + + + E+I+ K KV+ +G +E +A+ +I AAG Sbjct: 59 ILGPELSNKMFEHAKKFGAEYAYGDIKEVID----GKEYKVVK-AGSKEYKARAVIIAAG 113 Query: 116 ARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGL---IMARRFA 172 A + +IG+ G++ G G + + G+E+++VG GD + + RFA Sbjct: 114 AEYK---KIGVPGEKELG--GRGVSYCAVCDGAFFKGKELVVVGGGDSAVEEGVYLTRFA 168 Query: 173 LEGARVKAVIELMPYPGGLARNVMILNDFN---IPLYLSHKVVEIRGK-GRVQRVKIVKV 228 + V +L A++++ F+ + + V EI + G+V V +V Sbjct: 169 SKVTIVHRRDKLR------AQSILQARAFDNEKVDFLWNKTVKEIHEENGKVGNVTLVDT 222 Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288 + G E D V I G++P K +G+ + G NDR+ET V GIF Sbjct: 223 ------VTGEESEFKTDGVFIYIGMLPLSKPFENLGITNE--EGYIETNDRMETKVEGIF 274 Query: 289 VAGN--ALVINDLVDYVVEQGELAAEGAKEFID 319 AG+ + +V G +AA+ + +++ Sbjct: 275 AAGDIREKSLRQIVT-ATGDGSIAAQSVQHYVE 306 >pir||T34868 probable glutamate synthase small chain - Streptomyces coelicolor >gi|5738513|emb|CAB52860.1| (AL109849) putative glutamate synthase small subunit [Streptomyces coelicolor A3(2)] Length = 487 Score = 81.9 bits (199), Expect = 1e-14 Identities = 91/347 (26%), Positives = 143/347 (40%), Gaps = 57/347 (16%) Query: 4 VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 VAVIG GPAG+AAA + G +V + + D +GG+L +GI FK E Sbjct: 147 VAVIGSGPAGLAAAQQLTRAGHTVAVYERADRVGGLLR------YGIPEFKMEKRHINRR 200 Query: 64 YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHAFE 123 + M R RT + + +D++KR + + AAG+ A + Sbjct: 201 IEQM-RAEGTRFRTGVEIGRDLKATDLKKRYDAV-------------VIAAGSTT--ARD 244 Query: 124 IGITGDRVAGIFTAGE----AQTLMDIYGIMP-----GREILIVGSGDVGLIMARRFALE 174 + + G + GI A E A + + + P G+ ++++G GD G + Sbjct: 245 LPVPGRELNGIHQAMEYLPLANKVQEGDYVAPPITAEGKHVVVIGGGDTGADCVGTAHRQ 304 Query: 175 GARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRV----------- 223 GA +E+MP PG R+ + P+ G RV V Sbjct: 305 GAASVTQLEIMPRPGE-ERDAVRQPWPTFPMLYKVTSAHEEGGERVYAVSTTHFEGDEDG 363 Query: 224 --------KIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK---LLTKVGVAIDPSTG 272 ++ VD L PGTE + V ++ G K L+ + G+ +D Sbjct: 364 NVQWLHMSEVEFVDGKLTSKPGTERKIPAQLVTLAMGFTGTDKDNGLVDQFGLELDER-- 421 Query: 273 GPIVNDR-LETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318 G I D +T VPG+FVAG+A L+ + + +G AA GA F+ Sbjct: 422 GNIARDADFQTNVPGVFVAGDAGRGQSLIVWAIAEGRSAARGADRFL 468 >emb|CAC12113.1| (AL445066) probable thioredoxin reductase [Thermoplasma acidophilum] Length = 319 Score = 80.0 bits (194), Expect = 5e-14 Identities = 78/292 (26%), Positives = 130/292 (43%), Gaps = 21/292 (7%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 +DV ++G G AG +AA+ A G SV ++D+ GG+ + P + + + G E Sbjct: 17 FDVVIVGAGAAGFSAAVYAARSGFSVAILDK-AVAGGLTAEA--PLVENYLGFKSIVGSE 73 Query: 62 FAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVIS-PSGIEEIRAKTIIYAAGARERH 120 A +L A++ E + I+K + + AK +I G +H Sbjct: 74 LA-----KLFADHAANYAKIREGVEVRSIKKTQGGFDIETNDDTYHAKYVIITTGTTHKH 128 Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180 +G+ G+ + F G + + G+ ++ +G G+ G I A + E + Sbjct: 129 ---LGVKGE--SEYFGKGTSYCSTCDGYLFKGKRVVTIGGGNSGAIAAISMS-EYVKNVT 182 Query: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF 240 +IE MP V + NIP ++ +V EI G G+ +V VK + G E Sbjct: 183 IIEYMPKYMCENAYVQEIKKRNIPYIMNAQVTEIVGDGK--KVTGVKYKD---RTTGEEK 237 Query: 241 WVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292 ++ D V I GLIP L GV +D G +V+ R T+VPG++ AG+ Sbjct: 238 LIETDGVFIYVGLIPQTSFLKDSGVKLD-ERGYIVVDSRQRTSVPGVYAAGD 288 >sp|O32823|TRXB_LISMO THIOREDOXIN REDUCTASE (TRXR) >gi|2246749|gb|AAB63804.1| (AF009622) thioredoxin reductase [Listeria monocytogenes] Length = 319 Score = 78.8 bits (191), Expect = 1e-13 Identities = 82/331 (24%), Positives = 140/331 (41%), Gaps = 42/331 (12%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCI----HPGFGIHYFKEE 56 +YDV +IG GPAGM AA+ L ++I E GG + +PGF + Sbjct: 7 IYDVIIIGAGPAGMTAALYTSRADLDTLMI-ERGVPGGQMVNTAEVENYPGF------DS 59 Query: 57 LTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIE-----KRLKVISPSGIEEIRAKTII 111 + GP+ + K+++ + + Y DI+ K K ++ +G + +A+ II Sbjct: 60 ILGPDLSDKMLSGAKQFGAEYA--------YGDIKEVVDGKEFKTVT-AGSKTYKARAII 110 Query: 112 YAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRF 171 A GA R ++G G+ + G + + RE+++VG GD + Sbjct: 111 IATGAEHR---KLGAAGEE--ELSGRGVSYCAVCDGAFFKNRELIVVGGGDSAVEEGTYL 165 Query: 172 ALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKG-RVQRVKIVKVDE 230 +V V D + + V EI G G +V K+V Sbjct: 166 TRYADKVTIVHRRDKLRAQQILQDRAFKDEKVDFIWNSTVEEIVGDGKKVTGAKLVST-- 223 Query: 231 NLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVA 290 + G+E + VD V I GL+P K +G+ D G + ++ + T +PGIF A Sbjct: 224 ----VDGSESIMPVDGVFIYVGLVPLTKAFLNLGITDD--EGYIVTDEEMRTNLPGIFAA 277 Query: 291 GN--ALVINDLVDYVVEQGELAAEGAKEFID 319 G+ A + +V G LA + A+++++ Sbjct: 278 GDVRAKSLRQIVT-ATGDGGLAGQNAQKYVE 307 >pir||F72705 probable thioredoxin reductase APE1061 - Aeropyrum pernix (strain K1) >gi|5104731|dbj|BAA80046.1| (AP000060) 343aa long hypothetical thioredoxin reductase [Aeropyrum pernix] Length = 343 Score = 78.0 bits (189), Expect = 2e-13 Identities = 91/346 (26%), Positives = 157/346 (45%), Gaps = 53/346 (15%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQC----IHPGFGIHYFKEEL 57 YD ++G GPAG++AAI +S +++ + +GG L +PG G Sbjct: 25 YDTVIVGAGPAGLSAAIYTTRFLMSTLIVSMD--VGGQLNLTNWIDDYPGMG-------- 74 Query: 58 TGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKR----LKVISPSGIEEIRAKTIIYA 113 G E A KL+ + A++V + +++ V G+ E++A+T+I A Sbjct: 75 -GLE-ASKLVESFKSHAEMFGAKIVTGVQVKTVDRLDDGWFLVRGSRGL-EVKARTVILA 131 Query: 114 AGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGRE-ILIVGSGDVGLIMARRFA 172 G+R R ++G+ G+ A + G + + + G++ +++VG GD A Sbjct: 132 VGSRRR---KLGVPGE--AELAGRGVSYCSVCDAPLFKGKDAVVVVGGGD--------SA 178 Query: 173 LEGARVKA----VIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVK 224 LEGA + + + L+ G + + NI L V EIRG+ RV+ V Sbjct: 179 LEGALLLSGYVGKVYLVHRRQGFRAKPFYVEEARKKPNIEFILDSIVTEIRGRDRVESV- 237 Query: 225 IVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTV 284 +VK ++ G E + VD + I G P +L +G+ D S G +V++ + T++ Sbjct: 238 VVK-----NKVTGEEKELRVDGIFIEIGSEPPKELFEAIGLETD-SMGNVVVDEWMRTSI 291 Query: 285 PGIFVAGNALVINDLVDYVV---EQGELAAEGAKEFIDNDGIRSRK 327 PGIF AG+ + VV G +AA A ++ G+ K Sbjct: 292 PGIFAAGDCTSMWPGFRQVVTAAAMGAVAAYSAYTYLQEKGLYKPK 337 >dbj|BAB07290.1| (AP001519) thioredoxin reductase (NADPH) [Bacillus halodurans] Length = 315 Score = 78.0 bits (189), Expect = 2e-13 Identities = 79/327 (24%), Positives = 144/327 (43%), Gaps = 34/327 (10%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQC----IHPGFGIHYFKEE 56 +YDV + G GPAGM AA+ LS +++ E GG + +PGF + Sbjct: 7 VYDVVIAGAGPAGMTAAVYTSRANLSTVMV-ERGVPGGQMANTEDVENYPGF------DH 59 Query: 57 LTGPEFAYKLMNRLRDVEVRTS-ARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAG 115 + GPE + K+ + + + EII+ D++ + +G +E +A+ +I A G Sbjct: 60 ILGPELSTKMFEHAKKFGAEYAYGDIKEIIDQGDLK-----LVKAGNKEYKARAVIVATG 114 Query: 116 ARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEG 175 A + ++G+ G++ + G + + G+E+++VG GD + A Sbjct: 115 AEYK---KLGVPGEK--ELSGRGVSYCAVCDGAFFKGKELVVVGGGDSAVEEAVYLTRFA 169 Query: 176 ARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRG-KGRVQRVKIVKVDENLRE 234 ++V + ++ I H V +I G G+V V I E+ + Sbjct: 170 SKVTIIHRRDQLRAQKILQQRAFDNDKIEFIWDHVVKQINGTDGKVSSVTI----EHAKT 225 Query: 235 IPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNA- 293 +F D V I G++P + + + + D G + N+ +ET+VPGIF AG+ Sbjct: 226 GEQQDF--KTDGVFIYIGMLPLNEAVKNLNILND--EGYIVTNEEMETSVPGIFAAGDVR 281 Query: 294 -LVINDLVDYVVEQGELAAEGAKEFID 319 + +V G LAA+ + +I+ Sbjct: 282 EKSLRQIVT-ATGDGSLAAQNVQHYIE 307 >gi|11499149 thioredoxin reductase (trxB) [Archaeoglobus fulgidus] >gi|7427758|pir||A69444 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Archaeoglobus fulgidus >gi|2649006|gb|AAB89692.1| (AE000995) thioredoxin reductase (trxB) [Archaeoglobus fulgidus] Length = 300 Score = 77.6 bits (188), Expect = 2e-13 Identities = 80/299 (26%), Positives = 138/299 (45%), Gaps = 35/299 (11%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGI-LPQCI--HPGFGIHYFKEEL 57 MYDVA+IGGGPAG+ AA+ + GL + + D + + L I +PGF E Sbjct: 1 MYDVAIIGGGPAGLTAALYSARYGLKTVFFETVDPVSQLSLAAKIENYPGF-------EG 53 Query: 58 TGPEFAYKLMNRLRDVEVRTSA--RVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAG 115 +G E L+ ++++ V+ A ++ ++ + VI+ G E AK II A G Sbjct: 54 SGME----LLEKMKEQAVKAGAEWKLEKVERVERNGETFTVIAEGG--EYEAKAIIVATG 107 Query: 116 ARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEG 175 + + E GI G+ + G + G+++++ GSG + A G Sbjct: 108 GKHK---EAGIEGE--SAFIGRGVSYCATCDGNFFRGKKVIVYGSGKEAIEDAIYLHDIG 162 Query: 176 ARVKAVIELMPYPGGLARNVMI--LNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLR 233 V V P A ++ + IP++ S + +I G G+V+ K+V + + Sbjct: 163 CEVTIVSRT---PSFRAEKALVEEVEKRGIPVHYSTTIRKIIGSGKVE--KVVAYNREKK 217 Query: 234 EIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292 E EF ++ D + ++ G+ P ++ ++GV D S G V+ T V G+F AG+ Sbjct: 218 E----EFEIEADGIFVAIGMRPATDVVAELGVERD-SMGYIKVDKEQRTNVEGVFAAGD 271 >gi|11498012 NADH oxidase (noxA-3) [Archaeoglobus fulgidus] >gi|7483900|pir||H69299 NADH oxidase (noxA-3) homolog - Archaeoglobus fulgidus >gi|2650233|gb|AAB90837.1| (AE001077) NADH oxidase (noxA-3) [Archaeoglobus fulgidus] Length = 551 Score = 77.3 bits (187), Expect = 3e-13 Identities = 78/309 (25%), Positives = 145/309 (46%), Gaps = 26/309 (8%) Query: 3 DVAVIGGGPAGMAAA--IKARELGLSVILIDENDYLGGILPQCIHPGF------GIHYFK 54 +V VIGGG AG+ AA I+ ++ S+ +++ Y+ L +C P + + + Sbjct: 2 NVVVIGGGAAGLKAASRIRRKDGDASITVVEAGKYVS--LGRCGLPYYVGGLVHEVDNLR 59 Query: 55 EELTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAA 114 E G +L++++V T EI K +K++ +E+ ++ A Sbjct: 60 ETTYGAVRDEAYFKKLKNIDVLTETVATEI---DRSRKTVKIVRNGSEDELNYDYLVIAT 116 Query: 115 GARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALE 174 GAR GI + V + +A EA+ +++++ + +++G+G +GL A AL+ Sbjct: 117 GARPAKPPIEGIEAEGVVTLTSAEEAEKIIEMWE-EGAEKAVVIGAGFIGLESAE--ALK 173 Query: 175 GARVKA-VIELMPY--PGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDEN 231 ++ VIE+M P L R + +L + +L K V + RV+ KIV D+ Sbjct: 174 NLDMEVTVIEMMDRVAPAMLDREMAVL----VENHLREKGVNVVTSTRVE--KIVSQDDK 227 Query: 232 LREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAG 291 +R + D V+++ G+ PN +L K G+ I TG V++ + T+ I+ G Sbjct: 228 VRAVIANGKEYPADVVVVATGIKPNSELAEKAGLKIG-ETGAIWVDEYMRTSDESIYAGG 286 Query: 292 NALVINDLV 300 + + LV Sbjct: 287 DCVETTCLV 295 >emb|CAA11554.1| (AJ223804) 2-oxoglutarate dehydrogenase, E3 subunit [Arabidopsis thaliana] Length = 472 Score = 76.9 bits (186), Expect = 4e-13 Identities = 95/363 (26%), Positives = 153/363 (41%), Gaps = 61/363 (16%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54 DV +IGGGP G AAIKA +LGL I++ LGG C++ G H + Sbjct: 10 DVVIIGGGPGGYVAAIKAAQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 66 Query: 55 E----------ELTGPEFAYKLMNRLRDVEVRTSARVVE------IINYSDIEKRLKVIS 98 E +++ E M +D V+ R VE +NY ++ K +S Sbjct: 67 EAKHVFANHGVKVSSVEVDLPAMLAQKDTAVKNLTRGVEGLFKKNKVNY--VKGYGKFLS 124 Query: 99 PSGIE---------EIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 PS + ++ K II A G+ + GIT D + + G A +L +I Sbjct: 125 PSEVSVDTIDGENVVVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLTEI--- 178 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAV---IELMPYPGGLARNVM--ILNDFNIP 204 ++++++G+G +GL M + G+ V V +++P G R L + Sbjct: 179 --PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAADIVPAMDGEIRKQFQRSLEKQKMK 236 Query: 205 LYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVG 264 L KVV + G ++ IV+ E G + ++ D V++SAG P L Sbjct: 237 FMLKTKVVGVDSSGDGVKL-IVEPAEG-----GEQTTLEADVVLVSAGRTPFTSGLDLEK 290 Query: 265 VAIDPSTGGPI-VNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDN 320 + ++ GG I VN+R T V G++ G+ + L E G E G +D Sbjct: 291 IGVETDKGGRILVNERFSTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDY 350 Query: 321 DGI 323 D + Sbjct: 351 DKV 353 >pir||B75551 glutamate synthase, small subunit - Deinococcus radiodurans (strain R1) >gi|6457850|gb|AAF09769.1|AE001880_6 (AE001880) glutamate synthase, small subunit [Deinococcus radiodurans] Length = 488 Score = 76.9 bits (186), Expect = 4e-13 Identities = 91/353 (25%), Positives = 149/353 (41%), Gaps = 40/353 (11%) Query: 4 VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 VAV+G GPAG+AAA + G V + ++ND +GG++ +GI FK + + + Sbjct: 146 VAVVGSGPAGLAAAQQLARAGHDVTVFEKNDRVGGLV------RYGIPDFKLDKSHIDRR 199 Query: 64 YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKV-ISPSGIEEIRAKTIIYAAGARERHAF 122 + M + V RT V + S I K ++P+ + E + ++ A G+ Sbjct: 200 IEQM-QAEGVTFRTGVLVGDWDENSKITNLSKERVTPAELRE-QFDAVVLAGGSETPR-- 255 Query: 123 EIGITGDRVAGIFTAGEAQTLMDIYGI---------MPGREILIVGSGDVGLIMARRFAL 173 ++ G + GI A E + G+ ++++G GD G Sbjct: 256 DLPAPGRELNGIHYAMEFLPQQNRVNAGDKFKGQIRADGKHVVVIGGGDTGSDCVGTSNR 315 Query: 174 EGARVKAVIELMPYPGGLARNVMILNDFNIPL--YLSHKVVEIR----------GK-GRV 220 GA E+MP P + + + L SH+ +R GK G+V Sbjct: 316 HGAAGVTQFEVMPQPPEQENKPLTWPYWPMKLRTSTSHEEGAVREFAIATKEFIGKGGKV 375 Query: 221 QRVKIVKV---DENLREIPGTEFWVDVDTVIISAGLI-PNVKLLTKVGVAIDPS---TGG 273 V+ V+V D L EIPG+E D V+++ G P +L GV DP G Sbjct: 376 TGVRTVRVEMKDGKLEEIPGSEETHKADLVLLAMGFTNPMQSVLDAFGVDKDPRGNVLAG 435 Query: 274 PIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFIDNDGIRSR 326 + T+VPG+F AG+ LV + + +G AA +F+ + + R Sbjct: 436 TEEHGGYLTSVPGVFAAGDMRRGQSLVVWAIREGRQAARAVDQFLMGESVLPR 488 >gb|AAF34796.1|AF228640_1 (AF228640) lipoamide dehydrogenase precursor [Arabidopsis thaliana] Length = 507 Score = 76.9 bits (186), Expect = 4e-13 Identities = 95/363 (26%), Positives = 153/363 (41%), Gaps = 61/363 (16%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54 DV +IGGGP G AAIKA +LGL I++ LGG C++ G H + Sbjct: 45 DVVIIGGGPGGYVAAIKAAQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 101 Query: 55 E----------ELTGPEFAYKLMNRLRDVEVRTSARVVE------IINYSDIEKRLKVIS 98 E +++ E M +D V+ R VE +NY ++ K +S Sbjct: 102 EAKHVFANHGVKVSSVEVDLPAMLAQKDTAVKNLTRGVEGLFKKNKVNY--VKGYGKFLS 159 Query: 99 PSGIE---------EIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 PS + ++ K II A G+ + GIT D + + G A +L +I Sbjct: 160 PSEVSVDTIDGENVVVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLTEI--- 213 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAV---IELMPYPGGLARNVM--ILNDFNIP 204 ++++++G+G +GL M + G+ V V +++P G R L + Sbjct: 214 --PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAADIVPAMDGEIRKQFQRSLEKQKMK 271 Query: 205 LYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVG 264 L KVV + G ++ IV+ E G + ++ D V++SAG P L Sbjct: 272 FMLKTKVVGVDSSGDGVKL-IVEPAEG-----GEQTTLEADVVLVSAGRTPFTSGLDLEK 325 Query: 265 VAIDPSTGGPI-VNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDN 320 + ++ GG I VN+R T V G++ G+ + L E G E G +D Sbjct: 326 IGVETDKGGRILVNERFSTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDY 385 Query: 321 DGI 323 D + Sbjct: 386 DKV 388 >sp|O06465|AHPF_XANCH ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi|2098747|gb|AAC45426.1| (U94336) alkyl hydroperoxide reductase subunit F [Xanthomonas campestris] Length = 530 Score = 76.1 bits (184), Expect = 7e-13 Identities = 77/301 (25%), Positives = 141/301 (46%), Gaps = 28/301 (9%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 +DV V+GGGPAG AAA+ A G+ + E + G +L F E GP+ Sbjct: 213 FDVLVVGGGPAGSAAAVYAARKGIRTGVAAER-FGGQVLDTMSIENF---ISVPETEGPK 268 Query: 62 FAYKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119 A L +R DV++ R ++I + + +++ +G +++KT+I + GAR R Sbjct: 269 MAAALEQHVRQYDVDIMNLQRAEQLIP-AGADGLIEIKLANG-ASLKSKTVILSTGARWR 326 Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179 G + G+ + G+ + ++G G+ G+ A++ A + Sbjct: 327 QMNVPGEDQYKNKGVAYCPHCDG-----PLFKGKRVAVIGGGNSGV----EAAIDLAGIV 377 Query: 180 AVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREI 235 A + L+ + L + ++ N+ + S + E+ G G+ + +V D +I Sbjct: 378 AHVTLVEFDDKLRADEVLQRKLRSLHNVRIITSAQTTEVLGDGQ-KVTGLVYKDRTGGDI 436 Query: 236 PGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALV 295 ++++ V + GL+PN + L + VA+ P G IV+DR +T VPG+F AG+A Sbjct: 437 Q----HIELEGVFVQIGLLPNTEFL-RGTVALSP-RGEIIVDDRGQTDVPGVFAAGDATT 490 Query: 296 I 296 + Sbjct: 491 V 491 >pir||B75024 glutamate synthase small chain. PAB1214 - Pyrococcus abyssi (strain Orsay) >gi|5459146|emb|CAB50632.1| (AJ248288) GLUTAMATE SYNTHASE SMALL CHAIN. [Pyrococcus abyssi] Length = 475 Score = 75.7 bits (183), Expect = 9e-13 Identities = 93/345 (26%), Positives = 148/345 (41%), Gaps = 60/345 (17%) Query: 4 VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 VAVIG GPAG+ A + ++G V + + GG+L +GI F+ E Sbjct: 157 VAVIGAGPAGLTCAAELAKMGYEVTIFEALHEPGGVL------AYGIPEFR---LPKEIL 207 Query: 64 YKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHA 121 K + +L+ VE++T V + P +EE A I AG + Sbjct: 208 RKELKKLKFLGVEIKTDHIVGRTVTI-----------PELLEEYDAIFISTGAGTPKL-- 254 Query: 122 FEIGITGDRVAGIFTAGEAQT---LMDIY-------GIMPGREILIVGSGDVGLIMARRF 171 + I G + GI++A E T LM Y I+ G+ ++++G+G+ + AR Sbjct: 255 --LKIPGINLNGIYSANEFLTRINLMKAYKFPEYDTPIVVGKRVIVIGAGNTAMDAARSA 312 Query: 172 ALEGARVKAVIELMPYPGG------LARNVMILNDFNIPLYLSHKVVEIRG--KGRVQRV 223 GA V ++ Y G V + + VE G +GRV+ V Sbjct: 313 LRLGAEV-----IIAYRRGKEDMTARIEEVQHAKEEGVKFMFFVNPVEFIGDEEGRVKAV 367 Query: 224 KIVKV-------DENLREIPGTEFW--VDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGP 274 K K+ R+I GT + V+ DTVII+ G PN K+L + + G Sbjct: 368 KFEKMKPLEERDKRGKRKIVGTGEYITVEADTVIIAIGQTPN-KILWRTTPGLKVREDGT 426 Query: 275 -IVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318 IV++ L T++PG+F G+A+ V + G AA+ E++ Sbjct: 427 IIVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHEYL 471 >emb|CAB60740.1| (Y18636) thioredoxine reductase [Staphylococcus aureus] Length = 311 Score = 75.7 bits (183), Expect = 9e-13 Identities = 88/334 (26%), Positives = 144/334 (42%), Gaps = 48/334 (14%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIH----PGFGIHYFKEEL 57 +D+A+IG GPAGM AA+ A L ++I E GG + PGF E + Sbjct: 6 FDIAIIGAGPAGMTAAVYASRANLKTVMI-ERGIPGGQMANTEEVENFPGF------EMI 58 Query: 58 TGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEK-----RLKVISPSGIEEIRAKTIIY 112 TGP+ + K+ + + + Y DI+ KVI+ G +E+ AK +I Sbjct: 59 TGPDLSTKMFEHAK--------KFGAVYQYGDIKSVEDKGEYKVIN-FGNKELTAKAVII 109 Query: 113 AAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGL---IMAR 169 A GA + +IG+ G++ G G + + + + ++G GD + Sbjct: 110 ATGAEYK---KIGVPGEQELG--GRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLT 164 Query: 170 RFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGK-GRVQRVKIVKV 228 +FA + V EL + ++ ND I SH + I K G+V V + Sbjct: 165 KFADKVTIVHRRDELRAQ--RILQDRAFKND-KIDFIWSHTLKSINEKDGKVGSVTLTST 221 Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288 + G+E + D V I G+ P +G+ D G + D + T+VPGIF Sbjct: 222 KD------GSEETHEADGVFIYIGMKPLTAPFKDLGITND--VGYIVTKDDMTTSVPGIF 273 Query: 289 VAGNA--LVINDLVDYVVEQGELAAEGAKEFIDN 320 AG+ + +V G +AA+ A E+I++ Sbjct: 274 AAGDVRDKGLRQIVT-ATGDGSIAAQSAAEYIEH 306 >pir||F82936 thioredoxin reductase UU074 [imported] - Ureaplasma urealyticum >gi|6899025|gb|AAF30479.1|AE002107_3 (AE002107) thioredoxin reductase [Ureaplasma urealyticum] Length = 309 Score = 75.3 bits (182), Expect = 1e-12 Identities = 85/333 (25%), Positives = 144/333 (42%), Gaps = 48/333 (14%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGG--ILPQCIHPGFGIHYFKEELT 58 +YD+ +IG GPAG+AAA+ A+ GL+VI++ E + GG L + GI+ + Sbjct: 5 VYDLVIIGAGPAGLAAAVYAKRSGLNVIIV-EKQFPGGKIALTSNVENYLGIN----SIP 59 Query: 59 GPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARE 118 GPE AYK+ ++ ++ V + I+ + K++K+ + + + KT+I A G Sbjct: 60 GPELAYKMYEQVLNLNVSIIYEAADEISLKEKYKKIKLTT----QTLITKTVIIATGTEN 115 Query: 119 RHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARV 178 R +G GI + + + ++GSG+ + A A V Sbjct: 116 RRLNILGELEFENKGISYCAICDG-----PLYKNKAVSVIGSGNSAVEEAIYLATIAKEV 170 Query: 179 KAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGT 238 + + + N NI +Y + + E G ++ +K + N Sbjct: 171 HLIANKPQFKAEQQLVQIANNTPNIKIYYNKQTFEFFGHQFLEGLKFRDLITN------- 223 Query: 239 EFWVDVDTVIISA-----GLIPNVKLLTKVGVAIDPSTGGPIVNDR-LETTVPGIFVAGN 292 +V T+ I A GL+P+ + + I G I D+ ++T+V GIF AG Sbjct: 224 ----EVTTLNIEANFTFIGLLPS--RINTNNLCIFNEVNGFITTDKNMQTSVCGIFAAG- 276 Query: 293 ALVINDLVDYVVEQ-------GELAAEGAKEFI 318 D+VD V Q G +AA AKE+I Sbjct: 277 -----DIVDKNVRQIATATNDGVIAALYAKEYI 304 >pir||H82668 subunit F of alkyl hydroperoxide reductase XF1531 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9106569|gb|AAF84340.1|AE003983_2 (AE003983) subunit F of alkyl hydroperoxide reductase [Xylella fastidiosa] Length = 571 Score = 75.3 bits (182), Expect = 1e-12 Identities = 78/307 (25%), Positives = 136/307 (43%), Gaps = 40/307 (13%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 +DV V+G GPAG AAA+ A G+ L+ E + G +L F E GP Sbjct: 254 FDVLVVGAGPAGTAAAVYAARKGVRTGLVAER-FGGQVLDTMTIENF---ISVPETDGPR 309 Query: 62 FAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIR--------AKTIIYA 113 L LR E V+I+N +E L +G E+R ++T+I + Sbjct: 310 MVAALEQHLRQYE-------VDIMNLQRVE-TLVPAGENGFIEVRLASGASLSSRTVILS 361 Query: 114 AGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFAL 173 GAR R G R G+ + G+ + ++G G+ G+ A+ Sbjct: 362 TGARWRQMNVPGEDEYRNKGVAYCPHCDG-----PLFKGKRVAVIGGGNSGV----EAAI 412 Query: 174 EGARVKAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVD 229 + A + + + L+ + L + ++ N+ + + + E+RG G+ + +V VD Sbjct: 413 DLAGIASYVTLLEFDTKLRADEVLQRKLRSMSNVEVIMGAQTTEVRGDGK-KVTGLVYVD 471 Query: 230 ENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFV 289 + G F + ++ V + GL+PN + L K V + P G +V++ T++PG+F Sbjct: 472 RS----TGGSFTLALEGVFVQIGLLPNTEWL-KGRVELSP-RGEIVVDECGHTSLPGVFA 525 Query: 290 AGNALVI 296 AG+A + Sbjct: 526 AGDATTV 532 >gb|AAG17888.1| (AF295339) dihydrolipoamide dehydrogenase precursor [Solanum tuberosum] Length = 504 Score = 74.9 bits (181), Expect = 2e-12 Identities = 96/362 (26%), Positives = 148/362 (40%), Gaps = 63/362 (17%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54 DV VIGGGP G AAIKA +LGL I++ LGG C++ G H F Sbjct: 42 DVVVIGGGPGGYVAAIKAAQLGLKTTCIEKRGTLGG---TCLNVGCIPSKALLHSSHMFH 98 Query: 55 E----------ELTGPEFAYKLMNRLRDVEVRTSARVVE------IINYSDIEKRLKVIS 98 E + + E M +D V R +E +NY ++ K +S Sbjct: 99 EAQHSFANHGVKFSSVEVDLPAMMGQKDKAVSNLTRGIEGLFKKNKVNY--VKGYGKFLS 156 Query: 99 PS---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 PS G ++ K II A G+ + GIT D + + G A L +I Sbjct: 157 PSEISVDTVEGGNSVVKGKNIIIATGSDVKGL--PGITIDEKKIVSSTG-ALALTEI--- 210 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAV---IELMPYPGGLARNVM--ILNDFNIP 204 + ++++G+G +GL M + G+ V V +++P G R L + Sbjct: 211 --PKRLVVIGAGYIGLEMGSVWGRLGSEVTVVEFASDIVPTMDGEVRKQFQRALEKQKMK 268 Query: 205 LYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTK 262 L+ KVV + G ++ + G + ++ D V++SAG +P L Sbjct: 269 FMLNTKVVSVDATGDGVKLTLEP------SAGGDQTILEADVVLVSAGRVPFTSGLGLDT 322 Query: 263 VGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFID 319 +GV D G +VN+R T VPG+ G+ + L E G E G + +D Sbjct: 323 IGVETD-KAGRILVNERFATNVPGVHAIGDVIPGPMLAHKAEEDGVACVEFIAGKEGHVD 381 Query: 320 ND 321 D Sbjct: 382 YD 383 >pir||G70655 probable small subunit of NADH-dependent glutamate synthase - Mycobacterium tuberculosis (strain H37RV) >gi|1781098|emb|CAB06232.1| (Z83864) gltD [Mycobacterium tuberculosis] Length = 488 Score = 74.1 bits (179), Expect = 3e-12 Identities = 85/349 (24%), Positives = 143/349 (40%), Gaps = 59/349 (16%) Query: 4 VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 VAV+G GPAG+AAA + G +V + + D +GG+L +GI FK E + Sbjct: 147 VAVVGSGPAGLAAAQQLTRAGHTVTVFEREDRIGGLLR------YGIPEFKMEKRHLDRR 200 Query: 64 YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAK--TIIYAAGARERHA 121 M R E R V I+ E++RA ++ A GA Sbjct: 201 LDQM-RSEGTEFRPGVNVGVDIS---------------AEKLRADFDAVVLAGGATAWR- 243 Query: 122 FEIGITGDRVAGIFTA----------GEAQTLMDIYGIMP----GREILIVGSGDVGLIM 167 E+ I G + G+ A E ++D G P G++++I+G GD G Sbjct: 244 -ELPIPGRELEGVHQAMEFLPWANRVQEGDDVLDEDGQPPITAKGKKVVIIGGGDTGADC 302 Query: 168 ARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLS-------HKVVEIRGK--- 217 +GA E+MP P + + +S +V + + Sbjct: 303 LGTVHRQGAIAVHQFEIMPRPPDARAESTPWPTYPLMYRVSAAHEEGGERVFSVNTEAFV 362 Query: 218 ---GRVQRVK---IVKVDENLREIPGTEFWVDVDTVIISAGLI--PNVKLLTKVGVAIDP 269 GRV ++ + +D ++ G++F ++ D V+++ G + LLT +GV Sbjct: 363 GTDGRVSALRAHEVTMLDGKFVKVEGSDFELEADLVLLAMGFVGPERAGLLTDLGVKFT- 421 Query: 270 STGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318 G D +T+VPG+FVAG+ L+ + + +G AA ++ Sbjct: 422 ERGNVARGDDFDTSVPGVFVAGDMGRGQSLIVWAIAEGRAAAAAVDRYL 470 >sp|O05204|AHPF_STAAU ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi|1916317|gb|AAB51152.1| (U92441) alkyl hydroperoxide reductase subunit F [Staphylococcus aureus] Length = 507 Score = 74.1 bits (179), Expect = 3e-12 Identities = 80/300 (26%), Positives = 140/300 (46%), Gaps = 37/300 (12%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYF--KEELTG 59 YDV ++GGGPA +AAI GL ++ D +GG ++ GI F +E TG Sbjct: 206 YDVLIVGGGPASGSAAIYTARKGLRTGIV--ADRIGG----QVNDTAGIENFITVKETTG 259 Query: 60 PEFAYKLMNRL--RDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117 EF+ L + D++ T R +I ++ +KV +G + +KT+I A GA Sbjct: 260 SEFSSNLAAHIDQYDIDAMTGIRATDI---EKTDEAIKVTLENG-AVLESKTVIIATGAG 315 Query: 118 ERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177 R ++ I G+ + G A + +++ ++G G+ G+ A++ A Sbjct: 316 WR---KLNIPGEE--QLINKGVAFCPHCDGPLFENKDVAVIGGGNSGV----EAAIDLAG 366 Query: 178 VKAVIELMPYPGGL-ARNVM---ILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLR 233 + + L + L A NV+ + + N+ + + K E+ G+ V ++ ++ Sbjct: 367 IVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMN---- 422 Query: 234 EIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDR-LETTVPGIFVAGN 292 G E +++D + + GL+PN L A++ + G IV DR T VPGIF AG+ Sbjct: 423 --TGEEHLLNLDGIFVQIGLLPNTSWLND---AVELNERGEIVIDRNNNTNVPGIFAAGD 477 >pir||D71076 probable glutamate synthase small chain - Pyrococcus horikoshii >gi|3257287|dbj|BAA29970.1| (AP000004) 472aa long hypothetical glutamate synthase small chain [Pyrococcus horikoshii] Length = 472 Score = 74.1 bits (179), Expect = 3e-12 Identities = 92/342 (26%), Positives = 152/342 (43%), Gaps = 55/342 (16%) Query: 4 VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 VAV+G GPAG+ A + ++G V + + GG+L +GI F+ + Sbjct: 151 VAVVGAGPAGLTCAGELAKMGYKVTIFEALHKPGGVL------AYGIPEFRLPKEILDHE 204 Query: 64 YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHAFE 123 K + L VE+RT V + + ++ ++E A I AG + Sbjct: 205 LKKLKML-GVEIRTDHVVGKTVTLDEL-----------LQEYDAVFIGTGAGTPKL---- 248 Query: 124 IGITGDRVAGIFTAGEAQT---LMDIYG-------IMPGREILIVGSGDVGLIMARRFAL 173 + I G + I++A E T LM Y I G++++++G+G+ + AR Sbjct: 249 LNIPGILLDRIYSANEFLTRINLMKAYEFPEYDTPIAVGKKVIVIGAGNTAMDAARSALR 308 Query: 174 EGARVKAVIELMPYPGG----LARNVMILN--DFNIPLYLSHKVVEIRG--KGRVQRVKI 225 GA V + Y G AR I + + + + VE G GRV+ VK Sbjct: 309 LGAEVT-----IAYRRGREDMTAREEEIKHAEEEGVKFEFFLQPVEFIGDENGRVKAVKF 363 Query: 226 VKV-------DENLREIPGTEFWV--DVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIV 276 + + R+I GT +V + DTVII+ GL PN K++T+ G G +V Sbjct: 364 ERTKPLEERDSKGKRKIVGTGEYVTLEADTVIIAIGLEPN-KIITEDGRLKTNPDGTIVV 422 Query: 277 NDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318 ++ L T++PG+F G+A+ V + G+ AA+ E+I Sbjct: 423 DENLMTSIPGVFAGGDAIRGEATVILAMGDGKRAAKAIDEYI 464 >sp|P09832|GLTD_ECOLI GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN (GLUTAMATE SYNTHASE BETA SUBUNIT) (NADPH-GOGAT) (GLTS BETA CHAIN) >gi|7448188|pir||G65112 glutamate synthase (NADPH) (EC 1.4.1.13) small chain - Escherichia coli >gi|606152|gb|AAA58015.1| (U18997) glutamate synthase, small subunit [Escherichia coli] >gi|1789606|gb|AAC76245.1| (AE000400) glutamate synthase, small subunit [Escherichia coli K12] Length = 472 Score = 73.7 bits (178), Expect = 3e-12 Identities = 85/352 (24%), Positives = 149/352 (42%), Gaps = 65/352 (18%) Query: 4 VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 VA+IG GPAG+A A G+ ++ D + +GG+L FGI FK E Sbjct: 149 VAIIGAGPAGLACADVLTRNGVKAVVFDRHPEIGGLLT------FGIPAFKLE------- 195 Query: 64 YKLMNRLRDVEVRTSARVVEIINYSDIEKRL--KVISPSGIEEIRAKTIIYAAGARERHA 121 EV T R EI IE +L +V ++++ + G + Sbjct: 196 ---------KEVMTRRR--EIFTGMGIEFKLNTEVGRDVQLDDLLSDYDAVFLGVGTYQS 244 Query: 122 FEIGITGDRVAGIFTA------------GEAQTLMDIYGIMPGREILIVGSGDVGLIMAR 169 G+ + G++ A G +T + + M G+ ++++G GD + R Sbjct: 245 MRGGLENEDADGVYAALPFLIANTKQLMGFGETRDEPFVSMEGKRVVVLGGGDTAMDCVR 304 Query: 170 RFALEGAR-----VKAVIELMPYPGGLARNVMILNDFNIPLYLSHKV--VEIRGKGRVQR 222 +GA+ + E MP G R V + + + + +E+ G G+V Sbjct: 305 TSVRQGAKHVTCAYRRDEENMP---GSRREVKNAREEGVEFKFNVQPLGIEVNGNGKVSG 361 Query: 223 VKIVKVD---------ENLREIPGTEFWVDVDTVIISAGLIP-NVKLLTKVGVAIDPSTG 272 VK+V+ + + G+E V D VI++ G P N++ L K V +D + Sbjct: 362 VKMVRTEMGEPDAKGRRRAEIVAGSEHIVPADAVIMAFGFRPHNMEWLAKHSVELD--SQ 419 Query: 273 GPIV-----NDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFID 319 G I+ ++ +T+ P IF G+ + +DLV + +G AA+G +++ Sbjct: 420 GRIIAPEGSDNAFQTSNPKIFAGGDIVRGSDLVVTAIAEGRKAADGIMNWLE 471 >dbj|BAA21091.1| (D86223) glutamate synthase [Pyrococcus sp.] Length = 481 Score = 73.4 bits (177), Expect = 5e-12 Identities = 91/339 (26%), Positives = 145/339 (41%), Gaps = 50/339 (14%) Query: 4 VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 VA+IG GPAG+ AA + +LG V + + GG+L +GI F+ E Sbjct: 159 VAIIGAGPAGLTAAGELAKLGYDVTIYEALHEPGGVLM------YGIPEFR---LPKEIV 209 Query: 64 YKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHA 121 K + +LR V++ T V + ++ ++E A I AG Sbjct: 210 NKEIEKLRKLGVKILTDHVVGRTVTIEEL-----------LQEYDAVFIGSGAGTPRL-- 256 Query: 122 FEIGITGDRVAGIFTAGEAQT---LMDIY-------GIMPGREILIVGSGDVGLIMARRF 171 I G + GI+TA E T LM Y + G++++++G+G+ + AR Sbjct: 257 --INAPGINLNGIYTANEFLTRVNLMKAYLFPEYDTPVYVGKKVIVIGAGNTAMDAARSA 314 Query: 172 ALEGARVKAVIELMPYP-GGLARNVMILNDFNIPLYLSHKVVEIRG--KGRVQRVKIVK- 227 GA V V + I VE G GRV+ VK K Sbjct: 315 RRFGAEVTIAYRRGEEDVSAREEEVEHAKEEGIKFVYFVNPVEFIGDENGRVKAVKFEKM 374 Query: 228 --VDE----NLREIPGTEFWV--DVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDR 279 +DE R+I GT +V + DTVII+ G PN ++ G+ ++ G +V++ Sbjct: 375 KALDERDARGKRKIVGTGEYVTLEADTVIIAIGKHPNRLIINTPGLKVE--RGKIVVDEN 432 Query: 280 LETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318 L T++PG+F G+A+ V + G AA+ E++ Sbjct: 433 LMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHEYL 471 >gi|11497870 NADH oxidase (noxA-1) [Archaeoglobus fulgidus] >gi|7447165|pir||F69281 NADH oxidase (noxA-1) homolog - Archaeoglobus fulgidus >gi|2650383|gb|AAB90976.1| (AE001088) NADH oxidase (noxA-1) [Archaeoglobus fulgidus] Length = 439 Score = 73.4 bits (177), Expect = 5e-12 Identities = 85/307 (27%), Positives = 134/307 (42%), Gaps = 53/307 (17%) Query: 4 VAVIGGGPAGMAAA--IKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFK------- 54 VA+IGGG AGM+AA +KA V + +++ ++ H GI +F Sbjct: 3 VAIIGGGAAGMSAASRVKALRPNWDVKVFEKSRWVS-------HAPCGIPFFVGGAVEKF 55 Query: 55 EELTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAA 114 +EL + Y R R ++V T+ARVVEI E RL V +++A Sbjct: 56 DELCAYDIDY--FKRERGIDVHTNARVVEI-----EEGRLTVDEGGKEASYEWDKLLFAT 108 Query: 115 GARERHAFEIGITGDRVAGIFTAGEAQTLMDI-YGIMPGREILIVGSGDVGLIMARRFAL 173 G++ A + + G+ + G+ + + + M +++VGSG +G+ MA Sbjct: 109 GSK---AVRLNVEGENLEGVIYVDDIENAERVKIEAMKVDNVVVVGSGYIGVEMADAITR 165 Query: 174 EGARVKAVIELM-----PYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKV 228 G V VIE+M Y +A + + + L LS KV GK RV+ KV Sbjct: 166 LGKNV-TVIEVMERPLPEYDAEIAAIIKSEMEKYVNLRLSEKVTAFEGKDRVE-----KV 219 Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKL---LTKVGVAIDPSTGGPIVNDRLETTVP 285 N E P + II+ G+ PN L ++GV G N R+ET+ Sbjct: 220 VTNKGEYP-------CELAIIAVGVAPNTDLAKGFVELGV-----KGAIRTNSRMETSRE 267 Query: 286 GIFVAGN 292 ++ AG+ Sbjct: 268 NVYAAGD 274 >dbj|BAB05342.1| (AP001512) unknown conserved protein [Bacillus halodurans] Length = 322 Score = 73.4 bits (177), Expect = 5e-12 Identities = 78/325 (24%), Positives = 138/325 (42%), Gaps = 35/325 (10%) Query: 4 VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 V ++GGGP G+AAAI + GL ++I++++ + I H F K E+ F Sbjct: 6 VIIVGGGPCGLAAAIALQNEGLKPLVIEKDNIVSAIHRYPTHQTFFSTSEKLEIGQVPFL 65 Query: 64 --------------YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKT 109 Y+ + + + + V RV+++ D V++ K Sbjct: 66 TEERKPKRSQALVYYREVVKRKQIRVNPFERVIKVTKQED--GTFYVVTSK--RTYHCKQ 121 Query: 110 IIYAAGARERHAFEIGITGDRVAGIF-TAGEAQTLMDIYGIMPGREILIVGSGDVGLIMA 168 ++ A G + H +G+ G+ + +F EA D ++++++G + + A Sbjct: 122 VVIATGYYD-HPNSLGVPGEDLPHVFHYFKEAHPYFD-------QDVVVIGGKNSAVDAA 173 Query: 169 RRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKV 228 GARV + Y + IL +F ++H V++ + +V+R+ +V Sbjct: 174 LELEKAGARVTVLYRGDTYSDSV--KPWILPEF--VSLVNHDKVKMVFRAQVKRITASEV 229 Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVN-DRLETTVPGI 287 + E G D V G P+ L +GVAID TG PI + + +ET V GI Sbjct: 230 E---YETQGERKAARADFVFAMIGYHPDHNFLKTMGVAIDHDTGRPIHDPETMETNVEGI 286 Query: 288 FVAGNALVINDLVDYVVEQGELAAE 312 F+AG N+ + +E G E Sbjct: 287 FIAGVIAAGNNANEIFIENGRFHGE 311 >pir||A49911 NADH oxidase (hydrogen peroxide-forming) (EC 1.6.-.-) - Amphibacillus xylanus >gi|216220|dbj|BAA33809.1| (AB018435) NADH oxidase [Amphibacillus xylanus] Length = 509 Score = 73.0 bits (176), Expect = 6e-12 Identities = 80/299 (26%), Positives = 138/299 (45%), Gaps = 36/299 (12%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYF--KEELTG 59 +DV VIGGGPAG ++AI A G+ V +I D GG + + GI F + G Sbjct: 209 FDVLVIGGGPAGASSAIYAARKGIRVGII--ADRFGGQVMDTL----GIENFIGTKYTEG 262 Query: 60 PEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKR-LKVISPSGIEEIRAKTIIYAAGARE 118 P+ ++ + + + V++ + +IEK+ L + +++KTII A GAR Sbjct: 263 PKLISEIEQHVNEYNI----DVMKGLRAHNIEKKDLFEVQLDNGAVLKSKTIILATGARW 318 Query: 119 RHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARV 178 R +IG+ G++ G A + G+ + +VG G+ G+ AL+ A + Sbjct: 319 R---DIGVPGEK--EYKNKGVAYCTHCDAPLFEGKHVAVVGGGNSGI----ESALDLAGI 369 Query: 179 KAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENLRE 234 + + + L + ++ N+ + L+ + EI G V+ + + N Sbjct: 370 VKHVTVFEFMSELKADAVLQERLRSLPNVDVILNAQTTEITGDETVKGISYIDRTTN--- 426 Query: 235 IPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRL-ETTVPGIFVAGN 292 E V++ I GL PN + L G ++ + G IV D+ +T+VPGIF AG+ Sbjct: 427 ---EEKHVELQGAFIQIGLAPNTEWL---GDTVERNQIGEIVIDKKGQTSVPGIFAAGD 479 >sp|O82864|AHPF_PSEPU ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi|3298356|dbj|BAA31469.1| (AB010689) AhpF [Pseudomonas putida] Length = 520 Score = 73.0 bits (176), Expect = 6e-12 Identities = 76/301 (25%), Positives = 136/301 (44%), Gaps = 28/301 (9%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 +DV V+GGGPAG AAAI A G+ + E + G +L F +E GP+ Sbjct: 212 FDVLVVGGGPAGAAAAIYAARKGIRTGVAAER-FGGQVLDTLAIENF---ISVQETEGPK 267 Query: 62 FAYKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119 A L ++ DV++ R +I + E L + +G ++AKT+I A GAR R Sbjct: 268 LATALEEHVKQYDVDIMNLQRGEALIPAA--EGGLHEVRLAGGASLKAKTVILATGARWR 325 Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179 G R G+ + G+ + ++G G+ G+ A++ A + Sbjct: 326 EMNVPGEQEYRGRGVAYCPHCDG-----PLFKGKRVAVIGGGNSGV----EAAIDLAGIV 376 Query: 180 AVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREI 235 A + L+ + L + ++ N+ + S E+ G G ++V ++ + + Sbjct: 377 AQVTLIEFDSQLRADAVLQRKLRSLPNVNVITSALTTEVLGNG--EKVTGLRYKDRSTD- 433 Query: 236 PGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALV 295 + V ++ + + GL+PN L K V + P G IV+ + +T++PG+F AG+ Sbjct: 434 --EQHEVALEGIFVQIGLLPNTDWL-KGTVELSP-RGEIIVDAKGQTSIPGVFAAGDVTT 489 Query: 296 I 296 + Sbjct: 490 V 490 >pir||H75052 NADH oxidase (noxa-1) PAB0936 - Pyrococcus abyssi (strain Orsay) >gi|5458830|emb|CAB50317.1| (AJ248287) NADH oxidase (noxA-1) [Pyrococcus abyssi] Length = 446 Score = 73.0 bits (176), Expect = 6e-12 Identities = 77/306 (25%), Positives = 137/306 (44%), Gaps = 48/306 (15%) Query: 4 VAVIGGGPAGMAAAIKARELG--LSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 V +IGGG AGM+AA + + L V + + +++ H GI Y E ++ E Sbjct: 10 VVIIGGGAAGMSAASRVKRLKPEWDVKVFEATEWVS-------HAPCGIPYVVEGISPTE 62 Query: 62 FAYKLMN-------RLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAA 114 KLM+ + R +++ +A V+E+ ++V G + +++A Sbjct: 63 ---KLMHYPPEVFIKKRGIDLHLNAEVIEVDT-----GYVRVREKDGEKSYEWDYLVFAN 114 Query: 115 GARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGR---EILIVGSGDVGLIMARRF 171 GA + I G + G+FTA + I M +++IVG G +GL MA F Sbjct: 115 GASPQVP---AIEGVDLKGVFTADLPPDAVAIREYMEKNRVEDVVIVGGGYIGLEMAEAF 171 Query: 172 ALEGARVKAVIE-----LMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIV 226 +G RV ++ + + + ++ L L V+ I GK RV++V + Sbjct: 172 VAQGKRVTMIVRGERILRRSFDKEVTDIIEEKLKQHVNLRLQEIVLRIEGKDRVEKV-VT 230 Query: 227 KVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPG 286 E D VI++ G+ PN++L ++GV I TG N++++T+V Sbjct: 231 DAGE-----------YRADLVILATGIKPNIELARQLGVRIG-ETGAIWTNEKMQTSVEN 278 Query: 287 IFVAGN 292 ++ AG+ Sbjct: 279 VYAAGD 284 >pir||G64491 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Methanococcus jannaschii >gi|1592167|gb|AAB99556.1| (U67594) thioredoxin reductase (trxB) [Methanococcus jannaschii] Length = 301 Score = 72.2 bits (174), Expect = 1e-11 Identities = 73/298 (24%), Positives = 131/298 (43%), Gaps = 33/298 (11%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCI---HPGFGIHYFKEEL 57 ++D +IG GP G+ A I A L+ + I++ + G I I +PGF EE+ Sbjct: 2 IHDTIIIGAGPGGLTAGIYAMRGKLNALCIEKENAGGRIAEAGIVENYPGF------EEI 55 Query: 58 TGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117 G E A K N + + E+I E+ KVI+ + E KTI+ A G + Sbjct: 56 RGYELAEKFKNHAE--KFKLPIIYDEVIKIETKERPFKVITKN--SEYLTKTIVIATGTK 111 Query: 118 ERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177 + ++G+ D+ G T+ D + + +E++++G ++ A L+ Sbjct: 112 PK---KLGLNEDKFIG--RGISYCTMCDAFFYL-NKEVIVIGRDTPAIMSA--INLKDIA 163 Query: 178 VKAVIELMPYPGGLARNVM---ILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLRE 234 K ++ A ++M + N+ + + K +EI G+ R + VKI Sbjct: 164 KKVIVITDKSELKAAESIMLDKLKEANNVEIIYNAKPLEIVGEERAEGVKI--------S 215 Query: 235 IPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292 + G E + D + IS G +PN + L G+ +D G ++ T + GI+ G+ Sbjct: 216 VNGKEEIIKADGIFISLGHVPNTEFLKDSGIELD-KKGFIKTDENCRTNIDGIYAVGD 272 >gi|4557525 dihydrolipoamide dehydrogenase precursor; E3 component of pyruvate dehydrogenase [Homo sapiens] >gi|118674|sp|P09622|DLDH_HUMAN DIHYDROLIPOAMIDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR >gi|66123|pir||DEHULP dihydrolipoamide dehydrogenase (EC 1.8.1.4) precursor - human >gi|307137|gb|AAA59527.1| (J03490) lipoamide dehydrogenase precursor old gene name 'LAD' [Homo sapiens] Length = 509 Score = 71.8 bits (173), Expect = 1e-11 Identities = 89/355 (25%), Positives = 158/355 (44%), Gaps = 65/355 (18%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF--------GIHYFK 54 DV VIG GP G AAIKA +LG + I++N+ LGG C++ G HY+ Sbjct: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG---TCLNVGCIPSKALLNNSHYY- 98 Query: 55 EELTGPEFAYK-------LMNRLRDVEVRTSA---------------RVVEIINYSDIEK 92 G +FA + +N + +E +++A +VV + Y I Sbjct: 99 HMAHGTDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITG 158 Query: 93 RLKVI---SPSGIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 + +V + G + I K I+ A G+ E F GIT D + + G A +L + Sbjct: 159 KNQVTATKADGGTQVIDTKNILIATGS-EVTPFP-GITIDEDTIVSSTG-ALSLKKV--- 212 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSH 209 +++++G+G +G+ + + GA V AV E + + GG+ ++ I +F Sbjct: 213 --PEKMVVIGAGVIGVELGSVWQRLGADVTAV-EFLGHVGGVGIDMEISKNF-------Q 262 Query: 210 KVVEIRGKGRVQRVKIV--------KVDENLREIPGTEFWV-DVDTVIISAGLIPNVKL- 259 ++++ +G K+ K+D ++ G + V D +++ G P K Sbjct: 263 RILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNL 322 Query: 260 -LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEG 313 L ++G+ +DP P VN R +T +P I+ G+ + L ++G + EG Sbjct: 323 GLEELGIELDPRGRIP-VNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEG 376 >gb|AAB01381.1| (L13761) dihydrolipoamide dehydrogenase [Homo sapiens] Length = 511 Score = 71.8 bits (173), Expect = 1e-11 Identities = 89/355 (25%), Positives = 158/355 (44%), Gaps = 65/355 (18%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF--------GIHYFK 54 DV VIG GP G AAIKA +LG + I++N+ LGG C++ G HY+ Sbjct: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG---TCLNVGCIPSKALLNNSHYY- 98 Query: 55 EELTGPEFAYK-------LMNRLRDVEVRTSA---------------RVVEIINYSDIEK 92 G +FA + +N + +E +++A +VV + Y I Sbjct: 99 HMAHGTDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITG 158 Query: 93 RLKVI---SPSGIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 + +V + G + I K I+ A G+ E F GIT D + + G A +L + Sbjct: 159 KNQVTATKADGGTQVIDTKNILIATGS-EVTPFP-GITIDEDTIVSSTG-ALSLKKV--- 212 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSH 209 +++++G+G +G+ + + GA V AV E + + GG+ ++ I +F Sbjct: 213 --PEKMVVIGAGVIGVELGSVWQRLGADVTAV-EFLGHVGGVGIDMEISKNF-------Q 262 Query: 210 KVVEIRGKGRVQRVKIV--------KVDENLREIPGTEFWV-DVDTVIISAGLIPNVKL- 259 ++++ +G K+ K+D ++ G + V D +++ G P K Sbjct: 263 RILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNL 322 Query: 260 -LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEG 313 L ++G+ +DP P VN R +T +P I+ G+ + L ++G + EG Sbjct: 323 GLEELGIELDPRGRIP-VNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEG 376 >emb|CAB57297.1| (AJ243598) NADH oxidase [Sulfolobus solfataricus] Length = 332 Score = 71.8 bits (173), Expect = 1e-11 Identities = 87/304 (28%), Positives = 136/304 (44%), Gaps = 39/304 (12%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 YD+ VIGGGP G+ A + +LID D LGG L ++P I Y L G + Sbjct: 4 YDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVS-LYPE-KIVYDVGGLAGIQ 61 Query: 62 FAYKLMNRL--------RDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYA 113 AY+L RL D++V A ++E N + I + + KTI A Sbjct: 62 -AYELAQRLIEQAKMFGPDIKVNELADMIEKTNDN------MWIVKTDKATYKTKTIFIA 114 Query: 114 AGARERHAFEIGITGD---RVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARR 170 AG + +G G+ G++ + + G+ +LIVG GD A Sbjct: 115 AGIGKIVPSRLGAKGEIEYENRGVYYTVRRKKDFE------GKRVLIVGGGD----SAVD 164 Query: 171 FALEGARVKAVIELMPYPGGL-ARNVMILNDFNIP-LYLSHKVVEIRGKGRVQRVKIVKV 228 +AL A V + L+ L A + F + +Y+ H++ E++G G I+ Sbjct: 165 WALTLAPVAKSVTLIHRRDQLRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAII-F 223 Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288 D +E E +DVD+VIIS G ++ + K GV + +VN R+ET +PG++ Sbjct: 224 DNRTKE----EKVLDVDSVIISIGYKGDLGNIPKWGVTM--KGRDIVVNGRMETNLPGVY 277 Query: 289 VAGN 292 G+ Sbjct: 278 AGGD 281 >gb|AAF21029.1|AF208523_2 (AF208523) HcnB [Pseudomonas aeruginosa] Length = 464 Score = 71.8 bits (173), Expect = 1e-11 Identities = 77/316 (24%), Positives = 132/316 (41%), Gaps = 43/316 (13%) Query: 6 VIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQ-CIHPGFGIHYFKEELTGPEFAY 64 ++GGG AGMAAAI+ G+ +L DE GG++ + + G Y T Sbjct: 7 IVGGGSAGMAAAIELARRGVPCVLFDEASRPGGVVYRGPLRAGVDPAYLGARYT------ 60 Query: 65 KLMNRLR--------DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGA 116 +++ +LR +++R ++RVV D ++ + + + E+ ++ A G Sbjct: 61 RMLEKLRRDFSACAGHIDLRLNSRVVG----GDGQRLMVLDEAERLHEVEYSHLLLATGC 116 Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176 ER + G + G+ G Q + + P + LI GSG + ++A + G Sbjct: 117 HER---SVRFPGWTLPGVMLLGGLQLQIKSGVVKPLGDTLIAGSGPLLPLVACQLHAAGV 173 Query: 177 RVKAVIELMPYPGGLARNVMILND-----------------FNIPLYLSHKVVEIRGKGR 219 RV V E + G +AR + L + IPL+ VVE G G Sbjct: 174 RVAGVYEACAF-GRMARESLALLNKPQLFLDGLSMLGYLKLNGIPLHYGWGVVEASGDGE 232 Query: 220 VQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPI---V 276 + V + DE R V T+ + G IP +L ++G+ S G + Sbjct: 233 LTEVTVAPYDEEWRPDLENARPVKASTLAVGYGFIPRTQLSQQLGLEHGFSDDGYLRAEC 292 Query: 277 NDRLETTVPGIFVAGN 292 N +++ P I +AG+ Sbjct: 293 NVWQQSSQPHIHLAGD 308 >gb|AAF34795.1|AF228639_1 (AF228639) lipoamide dehydrogenase precursor [Arabidopsis thaliana] Length = 497 Score = 71.8 bits (173), Expect = 1e-11 Identities = 91/362 (25%), Positives = 151/362 (41%), Gaps = 59/362 (16%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54 DV +IGGGP G AAIKA +LGL I++ LGG C++ G H + Sbjct: 35 DVVIIGGGPGGYVAAIKASQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 91 Query: 55 E----------ELTGPEFAYKLMNRLRDVEVRTSARVVEII----NYSDIEKRLKVISPS 100 E +++ E M +D V+ R +E + + ++ K ISP+ Sbjct: 92 EAKHSFANHGIKVSSVEVDLPAMLAQKDNAVKNLTRGIEGLFKKNKVTYVKGYGKFISPN 151 Query: 101 ---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMP 151 G ++ K II A G+ + GIT D + + G A +L ++ Sbjct: 152 EVSVETIDGGNTIVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLSEV----- 203 Query: 152 GREILIVGSGDVGLIMARRFALEGARVKAVI---ELMPYPGGLARNVM--ILNDFNIPLY 206 ++++++G+G +GL M + G+ V V +++P G R L + Sbjct: 204 PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAGDIVPSMDGEIRKQFQRSLEKQKMKFM 263 Query: 207 LSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTKVG 264 L KVV + ++ + + G + ++ D V++SAG P L K+G Sbjct: 264 LKTKVVSVDSSSDGVKLTVEPAE------GGEQSILEADVVLVSAGRTPFTSGLDLEKIG 317 Query: 265 VAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDND 321 V D G +VNDR + VPG++ G+ + L E G E G +D D Sbjct: 318 VETD-KAGRILVNDRFLSNVPGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDYD 376 Query: 322 GI 323 + Sbjct: 377 KV 378 >gb|AAF79529.1|AC023673_17 (AC023673) F21D18.28 [Arabidopsis thaliana] Length = 505 Score = 71.8 bits (173), Expect = 1e-11 Identities = 91/362 (25%), Positives = 151/362 (41%), Gaps = 59/362 (16%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54 DV +IGGGP G AAIKA +LGL I++ LGG C++ G H + Sbjct: 43 DVVIIGGGPGGYVAAIKASQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 99 Query: 55 E----------ELTGPEFAYKLMNRLRDVEVRTSARVVEII----NYSDIEKRLKVISPS 100 E +++ E M +D V+ R +E + + ++ K ISP+ Sbjct: 100 EAKHSFANHGIKVSSVEVDLPAMLAQKDNAVKNLTRGIEGLFKKNKVTYVKGYGKFISPN 159 Query: 101 ---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMP 151 G ++ K II A G+ + GIT D + + G A +L ++ Sbjct: 160 EVSVETIDGGNTIVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLSEV----- 211 Query: 152 GREILIVGSGDVGLIMARRFALEGARVKAVI---ELMPYPGGLARNVM--ILNDFNIPLY 206 ++++++G+G +GL M + G+ V V +++P G R L + Sbjct: 212 PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAGDIVPSMDGEIRKQFQRSLEKQKMKFM 271 Query: 207 LSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTKVG 264 L KVV + ++ + + G + ++ D V++SAG P L K+G Sbjct: 272 LKTKVVSVDSSSDGVKLTVEPAE------GGEQSILEADVVLVSAGRTPFTSGLDLEKIG 325 Query: 265 VAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDND 321 V D G +VNDR + VPG++ G+ + L E G E G +D D Sbjct: 326 VETD-KAGRILVNDRFLSNVPGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDYD 384 Query: 322 GI 323 + Sbjct: 385 KV 386 >pir||G83370 hydrogen cyanide synthase HcnB PA2194 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9948216|gb|AAG05582.1|AE004646_3 (AE004646) hydrogen cyanide synthase HcnB [Pseudomonas aeruginosa] Length = 464 Score = 71.8 bits (173), Expect = 1e-11 Identities = 77/316 (24%), Positives = 132/316 (41%), Gaps = 43/316 (13%) Query: 6 VIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQ-CIHPGFGIHYFKEELTGPEFAY 64 ++GGG AGMAAAI+ G+ +L DE GG++ + + G Y T Sbjct: 7 IVGGGSAGMAAAIELARRGVPCVLFDEASRPGGVVYRGPLRAGVDPAYLGARYT------ 60 Query: 65 KLMNRLR--------DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGA 116 +++ +LR +++R ++RVV D ++ + + + E+ ++ A G Sbjct: 61 RMLEKLRRDFSACAGHIDLRLNSRVVG----GDGQRLMVLDEAERLHEVEYSHLLLATGC 116 Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176 ER + G + G+ G Q + + P + LI GSG + ++A + G Sbjct: 117 HER---SVPFPGWTLPGVMLLGGLQLQIKSGVVKPLGDTLIAGSGPLLPLVACQLHAAGV 173 Query: 177 RVKAVIELMPYPGGLARNVMILND-----------------FNIPLYLSHKVVEIRGKGR 219 RV V E + G +AR + L + IPL+ VVE G G Sbjct: 174 RVAGVYEACAF-GRMARESLALLNKPQLFLDGLSMLGYLKLNGIPLHYGWGVVEASGDGE 232 Query: 220 VQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPI---V 276 + V + DE R V T+ + G IP +L ++G+ S G + Sbjct: 233 LTEVTVAPYDEEWRPDLENARPVKASTLAVGYGFIPRTQLSQQLGLEHGFSDDGYLRAEC 292 Query: 277 NDRLETTVPGIFVAGN 292 N +++ P I +AG+ Sbjct: 293 NVWQQSSQPHIHLAGD 308 >gb|AAG21579.1|AC051631_2 (AC051631) lipoamide dehydrogenase, putative; 44693-46402 [Arabidopsis thaliana] Length = 507 Score = 71.8 bits (173), Expect = 1e-11 Identities = 91/362 (25%), Positives = 151/362 (41%), Gaps = 59/362 (16%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54 DV +IGGGP G AAIKA +LGL I++ LGG C++ G H + Sbjct: 45 DVVIIGGGPGGYVAAIKASQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 101 Query: 55 E----------ELTGPEFAYKLMNRLRDVEVRTSARVVEII----NYSDIEKRLKVISPS 100 E +++ E M +D V+ R +E + + ++ K ISP+ Sbjct: 102 EAKHSFANHGIKVSSVEVDLPAMLAQKDNAVKNLTRGIEGLFKKNKVTYVKGYGKFISPN 161 Query: 101 ---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMP 151 G ++ K II A G+ + GIT D + + G A +L ++ Sbjct: 162 EVSVETIDGGNTIVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLSEV----- 213 Query: 152 GREILIVGSGDVGLIMARRFALEGARVKAVI---ELMPYPGGLARNVM--ILNDFNIPLY 206 ++++++G+G +GL M + G+ V V +++P G R L + Sbjct: 214 PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAGDIVPSMDGEIRKQFQRSLEKQKMKFM 273 Query: 207 LSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTKVG 264 L KVV + ++ + + G + ++ D V++SAG P L K+G Sbjct: 274 LKTKVVSVDSSSDGVKLTVEPAE------GGEQSILEADVVLVSAGRTPFTSGLDLEKIG 327 Query: 265 VAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDND 321 V D G +VNDR + VPG++ G+ + L E G E G +D D Sbjct: 328 VETD-KAGRILVNDRFLSNVPGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDYD 386 Query: 322 GI 323 + Sbjct: 387 KV 388 >sp|P09623|DLDH_PIG DIHYDROLIPOAMIDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR >gi|66122|pir||DEPGLP dihydrolipoamide dehydrogenase (EC 1.8.1.4) precursor - pig >gi|164539|gb|AAA31069.1| (J03489) lipoamide dehydrogenase precursor [Sus scrofa] Length = 509 Score = 71.4 bits (172), Expect = 2e-11 Identities = 87/355 (24%), Positives = 158/355 (44%), Gaps = 65/355 (18%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF--------GIHYFK 54 DV VIG GP G AAIKA +LG + I++N+ LGG C++ G HY+ Sbjct: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG---TCLNVGCIPSKALLNNSHYY- 98 Query: 55 EELTGPEFAYK-------LMNRLRDVEVRTSA---------------RVVEIINYSDIEK 92 G +FA + +N + +E +++A +VV + Y I Sbjct: 99 HMAHGKDFASRGIEMSEVRLNLEKMMEQKSNAVKALTGGIAHLFKQNKVVRVNGYGKITG 158 Query: 93 RLKVI---SPSGIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 + +V + E I K I+ A G+ E F GIT D + + G A +L + Sbjct: 159 KNQVTATKADGSTEVINTKNILIATGS-EVTPFP-GITIDEDTVVSSTG-ALSLKKV--- 212 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSH 209 +++++G+G +G+ + + GA V AV EL+ + GG+ ++ + +F Sbjct: 213 --PEKMVVIGAGVIGVELGSVWQRLGADVTAV-ELLGHVGGIGIDMEVSKNF-------Q 262 Query: 210 KVVEIRGKGRVQRVKIV--------KVDENLREIPGTEFWV-DVDTVIISAGLIPNVKL- 259 ++++ +G K++ +D ++ G + V D +++ G P + Sbjct: 263 RILQKQGFKFKLNTKVIGATKKSDGNIDVSIEAASGGKAEVITCDVLLVCIGRRPFTQNL 322 Query: 260 -LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEG 313 L ++G+ +DP P VN R +T +P I+ G+ + L ++G + EG Sbjct: 323 GLEELGIELDPRGRIP-VNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEG 376 >gb|AAA35764.1| (J03620) dihydrolipoamide dehydrogenase precursor [Homo sapiens] Length = 509 Score = 71.4 bits (172), Expect = 2e-11 Identities = 89/355 (25%), Positives = 158/355 (44%), Gaps = 65/355 (18%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF--------GIHYFK 54 DV VIG GP G AAIKA +LG + I++N+ LGG C++ G HY+ Sbjct: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG---TCLNVGCIPSKALLNNSHYY- 98 Query: 55 EELTGPEFAYK-------LMNRLRDVEVRTSA---------------RVVEIINYSDIEK 92 G +FA + +N + +E +++A +VV + Y I Sbjct: 99 HMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYRKITG 158 Query: 93 RLKVI---SPSGIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 + +V + G + I K I+ A G+ E F GIT D + + G A +L + Sbjct: 159 KNQVTATKADGGTQVIDTKNILIATGS-EVTPFP-GITIDEDTIVSSTG-ALSLKKV--- 212 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSH 209 +++++G+G +G+ + + GA V AV E + + GG+ ++ I +F Sbjct: 213 --PEKMVVIGAGVIGVELGSVWQRLGADVTAV-EFLGHVGGVGIDMEISKNF-------Q 262 Query: 210 KVVEIRGKGRVQRVKIV--------KVDENLREIPGTEFWV-DVDTVIISAGLIPNVKL- 259 ++++ +G K+ K+D ++ G + V D +++ G P K Sbjct: 263 RILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNL 322 Query: 260 -LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEG 313 L ++G+ +DP P VN R +T +P I+ G+ + L ++G + EG Sbjct: 323 GLEELGIELDPRGRIP-VNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEG 376 >pir||E69194 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621795|gb|AAB85213.1| (AE000850) thioredoxin reductase [Methanobacterium thermoautotrophicum] Length = 303 Score = 71.4 bits (172), Expect = 2e-11 Identities = 79/298 (26%), Positives = 133/298 (44%), Gaps = 35/298 (11%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDY--LGGILPQC-IHPGFGIHYFKEELT 58 YD+ VIG GPAG+ A I G SV+++D+ LG +P +PGF E + Sbjct: 5 YDMIVIGAGPAGLTAGIYGGRQGSSVLMLDKGPAGGLGLEVPMMENYPGF------EMIA 58 Query: 59 GPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARE 118 G K+ + V A + E+ +IEK + + A II+A G++ Sbjct: 59 GMSLVTKMKKQATAV-----AELREMEEVKEIEKGDVFTVKTSRDTYTASAIIFATGSKH 113 Query: 119 RHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARV 178 R ++G+ G+ + G + GR++L+VG G+ A + A+ + Sbjct: 114 R---QLGVPGEN--DLLGRGVCYCATCDGPLYKGRKVLMVGGGN----SAAQEAVFLKNI 164 Query: 179 KAVIELMPYPGGLARNVMI---LNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREI 235 + ++ L + + L + IP+ + V EI G RV+ V I + Sbjct: 165 GCDVSIVHRRDELRADKYLQDKLREMEIPVIWNSVVKEIGGDERVEEVII------HNRV 218 Query: 236 PGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLE-TTVPGIFVAGN 292 G + + VD V I+ G P +L +GV +D GG I+ D+ + T VP ++ AG+ Sbjct: 219 TGRDETLKVDGVFIAIGEEPLNQLAVDLGVEVD--KGGYIITDKFQRTNVPLVYAAGD 274 >pir||H71171 probable NADH oxidase - Pyrococcus horikoshii >gi|3256978|dbj|BAA29661.1| (AP000002) 445aa long hypothetical NADH oxidase [Pyrococcus horikoshii] Length = 445 Score = 71.4 bits (172), Expect = 2e-11 Identities = 73/303 (24%), Positives = 140/303 (46%), Gaps = 42/303 (13%) Query: 4 VAVIGGGPAGMAAAIKARELG--LSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 V +IGGG AGM+AA + + L V + + +++ H GI Y E L+ P+ Sbjct: 9 VVIIGGGAAGMSAASRVKRLKPEWDVKVFEATEWVS-------HAPCGIPYVVEGLSTPD 61 Query: 62 ----FAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117 + ++ + R +++ +A V+E+ ++V G + +++A GA Sbjct: 62 KLMYYPPEVFIKKRGIDLHLNAEVIEVDT-----GYVRVRENGGEKSYEWDYLVFANGAS 116 Query: 118 ERHAFEIGITGDRVAGIFTAG---EAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALE 174 + I G + G+FTA +A + + ++I+G G +G+ MA FA + Sbjct: 117 PQVP---AIEGVNLKGVFTADLPPDALAIREYMEKYKVENVVIIGGGYIGIEMAEAFAAQ 173 Query: 175 GARVKAVI--ELMPYPGGLARNVMILND---FNIPLYLSHKVVEIRGKGRVQRVKIVKVD 229 G V ++ E + IL + ++ L L ++I G+ RV++V + Sbjct: 174 GKNVTMIVRGERVLRRSFDKEVTDILEEKLKKHVNLRLQEITMKIEGEERVEKV-VTDAG 232 Query: 230 ENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFV 289 E E+ VI++ G+ PN++L ++GV I TG N++++T+V ++ Sbjct: 233 EYKAEL-----------VILATGIKPNIELAKQLGVRIG-ETGAIWTNEKMQTSVENVYA 280 Query: 290 AGN 292 AG+ Sbjct: 281 AGD 283 >sp|P50970|DLDH_ZYMMO DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONENT OF PYRUVATE AND 2-OXOGLUTARATE DEHYDROGENASES COMPLEXES) >gi|1747421|emb|CAA57734.1| (X82291) dihydrolipoamide dehydrogenase [Zymomonas mobilis] >gi|2995393|emb|CAA63810.1| (X93605) dihydrolipoamide dehydrogenase [Zymomonas mobilis] Length = 466 Score = 71.0 bits (171), Expect = 2e-11 Identities = 93/355 (26%), Positives = 161/355 (45%), Gaps = 72/355 (20%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG-------------- 47 +D+ V+GGGP G AAI+A +L L V L+ E +LGGI C++ G Sbjct: 5 FDLIVLGGGPGGYVAAIRAAQLNLKVALV-ERVHLGGI---CLNWGCIPTKSLLRSAEVY 60 Query: 48 --------FGIHYFKEELTGPEFAY-KLMNRLRDVEVRTSARVVEIINYSDIE------- 91 +G+ FK P+F K++ R R+V R ++ V ++ + +E Sbjct: 61 HEMQNAEAYGLTSFK-----PDFDLDKIIARSREVAARLASGVKTLLRKNKVEVISGVGQ 115 Query: 92 ----KRLKVISPSGIEEI-RAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDI 146 ++++V + G E+I AK II A GAR R + G + A + Sbjct: 116 LTGNQQMRVETTEGEEKILEAKDIIIATGARARQLPNVHSDGKHIWTYHHALKPPA---- 171 Query: 147 YGIMPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLY 206 MP +++L++GSG +G+ A +A GA V +++E P ++ + D + Y Sbjct: 172 ---MP-KKLLVIGSGAIGIEFASLYADFGAEV-SIVEHAP-------QILPMEDAEVSAY 219 Query: 207 LSHKVVEIRGKGRVQRVKIVKV---DENL-REIPGTEFWVDVDT---VIISAGLIPNVKL 259 ++ K + RG + + + + DE + EI G + V + I++ G++ NV+ Sbjct: 220 VA-KAFKKRGIRILTQSALQNLTPDDEGVTAEIAGADGKVTKERFSHAIVAIGVVANVEN 278 Query: 260 --LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE 312 L K+G+ +D G V+ T V ++ G+ L QG +AAE Sbjct: 279 IGLDKLGIKLD--RGFIAVDGFGRTNVDHVWAIGDVAGAPCLAHKASHQGVIAAE 331 >gi|11498007 NADH oxidase (noxA-2) [Archaeoglobus fulgidus] >gi|7447164|pir||C69299 NADH oxidase (noxA-2) homolog - Archaeoglobus fulgidus >gi|2650234|gb|AAB90838.1| (AE001077) NADH oxidase (noxA-2) [Archaeoglobus fulgidus] Length = 436 Score = 71.0 bits (171), Expect = 2e-11 Identities = 75/296 (25%), Positives = 134/296 (44%), Gaps = 31/296 (10%) Query: 4 VAVIGGGPAGMAAA--IKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 V VIGGG AGM+AA +KA + V + +E +++ H GI Y E L+ P Sbjct: 3 VVVIGGGAAGMSAASRVKALQPEWEVTVFEETNFVS-------HAPCGIPYVVEGLSDPS 55 Query: 62 ----FAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117 + + R +++ +A+VVE + ++VI + ++ A GA Sbjct: 56 HLMYYPPEFFREKRGIDLHINAKVVEA-----GDGFVRVIEDGQEKTYEWDKLVIATGAL 110 Query: 118 ERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177 + G+ + V + +A L + + ++IVG+G VG+ MA A G + Sbjct: 111 PKTPPFEGLELENVFTVRHPVQAAELRE--AVEKAENVVIVGAGYVGVEMAEAAAARGKK 168 Query: 178 VKAVIELMPYP-GGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIP 236 V V+E + P L R+V L + HK+ E ++V+ + D +R++ Sbjct: 169 V-TVVEFLDQPLPNLDRDVADL--------VKHKLEEKVNLRLGEKVEAFEGDGAVRKVV 219 Query: 237 GTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292 + D VI++ G+ N + ++G I TG + R++T+V +F AG+ Sbjct: 220 TDKGEYPADVVIVATGVKANTAIAEQIGCKIG-ETGAIWTDSRMQTSVENVFAAGD 274 >emb|CAA11546.1| (AJ223781) thioredoxin reductase [Staphylococcus aureus] Length = 311 Score = 71.0 bits (171), Expect = 2e-11 Identities = 86/334 (25%), Positives = 142/334 (41%), Gaps = 48/334 (14%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIH----PGFGIHYFKEEL 57 +D+A+IG GPAGM AA+ A L ++I E GG + PGF E + Sbjct: 6 FDIAIIGAGPAGMTAAVYASRANLKTVMI-ERGIPGGQMANTEEVENFPGF------EMI 58 Query: 58 TGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEK-----RLKVISPSGIEEIRAKTIIY 112 TGP+ + K+ + + + Y DI+ KVI+ G +E+ AK +I Sbjct: 59 TGPDLSTKMFEHAK--------KFGAVYQYGDIKSVEDKGEYKVIN-FGNKELTAKAVII 109 Query: 113 AAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGL---IMAR 169 A GA + +IG+ G++ G G + + + + ++G GD + Sbjct: 110 ATGAGYK---KIGVPGEQELG--GRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLT 164 Query: 170 RFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGK-GRVQRVKIVKV 228 +FA + V EL + ++ ND I SH + I K G+V V + Sbjct: 165 KFADKVTIVHRRDELRAQ--RILQDRAFKND-KIDFIWSHTLKSINEKDGKVGSVTLTST 221 Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288 + G+E + D V I G+ P +G+ D G + D + T+VPGIF Sbjct: 222 KD------GSEETHEADGVFIYIGMKPLTAPFKDLGITND--VGYIVTKDDMTTSVPGIF 273 Query: 289 VAGNA--LVINDLVDYVVEQGELAAEGAKEFIDN 320 AG+ + +V G +AA+ +I++ Sbjct: 274 AAGDVRDKGLRQIVT-ATGDGSIAAQSTSGYIEH 306 >pir||D72382 hypothetical protein TM0395 - Thermotoga maritima (strain MSB8) >gi|4980899|gb|AAD35480.1|AE001719_6 (AE001719) NADH oxidase, putative [Thermotoga maritima] Length = 425 Score = 71.0 bits (171), Expect = 2e-11 Identities = 78/313 (24%), Positives = 143/313 (44%), Gaps = 49/313 (15%) Query: 6 VIGGGPAGMAAAIKARELGLS--VILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 ++G GPAG+ A RE+ ++LI Y+G P + ++T + Sbjct: 5 IVGSGPAGLNAIEAIREVDKEGEILLITAEKYVGYSRPLITY------LLGRKVTEEKMY 58 Query: 64 YKLMNRLRD--VEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHA 121 Y+ + LR+ V+++ + RV ++I + V++ SG EEIR ++ A G + Sbjct: 59 YRTEDYLREMRVDIKPATRVEKVI-----PEEKTVVTDSG-EEIRYDKLLIATGGKPFVP 112 Query: 122 FEIGITGDRVAGIFTAGEAQTLMDIY-GIMPGREILIVGSGDVGLIMARRFALEGARVKA 180 G+TG + FT E + ++ Y +E +++G G +GL +A Sbjct: 113 NIEGLTGKKGVFTFTTWEDEEKVEKYIEENDVKEAVVLGGGLIGL----------KTTEA 162 Query: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEI-------RGKGRVQRVKIVKV--DEN 231 ++EL G+ ++ L D + + K EI G + +VKV D+ Sbjct: 163 LMEL-----GVKVTIVELADRILSVTFDRKASEIITEALKKEGCSVITNDTVVKVNGDDT 217 Query: 232 LREI---PGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288 + + G E + ++I+ G+ PNV+ L G+ I+ G +VN+++ET V G++ Sbjct: 218 VSSVVLKSGKE--IPTKLLVIAIGVKPNVEFLKDSGIEINR---GIVVNEKMETNVEGVY 272 Query: 289 VAGNALVINDLVD 301 AG+ DL+D Sbjct: 273 AAGDCTEFYDLID 285 >gb|AAD52148.1|AF129406_2 (AF129406) alkyl hydroperoxide reductase subunit F [Bacteroides fragilis] Length = 516 Score = 71.0 bits (171), Expect = 2e-11 Identities = 81/328 (24%), Positives = 143/328 (42%), Gaps = 39/328 (11%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 YDV V GGGPAG AAAI + GL+V +I E +GG + + + G TG + Sbjct: 212 YDVIVAGGGPAGSAAAIYSARKGLNVAVIAER--IGGQVKETV--GIENLISVPSTTGSQ 267 Query: 62 FAYKLMNRLRDVEVRTSARVVEIINYSDIEK-----RLKVISPSGIEEIRAKTIIYAAGA 116 A L + S ++++ + IEK + KV++ G E A +I A GA Sbjct: 268 LADNLKTHM-------SQYPIDLLEHRQIEKIELDGKDKVLTAKGGERFSAPAVIVATGA 320 Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176 R ++ + G+ A G A G+++ +VG G+ G+ A++ A Sbjct: 321 SWR---KLNVPGE--AEYIGRGVAFCPHCDGPFYKGKQVAVVGGGNSGI----EAAIDLA 371 Query: 177 RVKAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENL 232 + + + ++ + L + ++ N+ + + + E+ G G +V ++V + Sbjct: 372 GICSKVTVLEFMDELKADQVLQEKLKSLPNVEVLVHSQTTEVVGNG--DKVTGIRVKDRK 429 Query: 233 REIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVND-RLETTVPGIFVAG 291 E E + +D + + GL+ N + V ++ + G IV D T VPGI+ AG Sbjct: 430 TE---EERVISLDGIFVQIGLVANSGIFRDV---VEVNRPGEIVIDAHCRTNVPGIYAAG 483 Query: 292 NALVINDLVDYVVEQGELAAEGAKEFID 319 + + ++ GE A F D Sbjct: 484 DVSTV-PYKQIIIAMGEGAKAALAAFED 510 >gb|AAK42391.1| Thioredoxin reductase (trxB-1) [Sulfolobus solfataricus] Length = 332 Score = 70.6 bits (170), Expect = 3e-11 Identities = 84/303 (27%), Positives = 133/303 (43%), Gaps = 37/303 (12%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 YD+ VIGGGP G+ A + +LID D LGG L ++P I Y L G + Sbjct: 4 YDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVS-LYPE-KIVYDVGGLAGIQ 61 Query: 62 FAYKLMNRL--------RDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYA 113 AY+L RL D++V A ++E N + I + + KTI A Sbjct: 62 -AYELAQRLIEQAKMFGPDIKVNELADMIEKTNDN------MWIVKTDKATYKTKTIFIA 114 Query: 114 AGARERHAFEIGITGD---RVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARR 170 AG + +G G+ G++ + + G+ +LIVG GD + A Sbjct: 115 AGIGKIVPSRLGAKGEIEYENRGVYYTVRRKKDFE------GKRVLIVGGGDSAVDWALT 168 Query: 171 FALEGARVKAVIELMPYPGGLARNVMILNDFNIP-LYLSHKVVEIRGKGRVQRVKIVKVD 229 A K+V + A + F + +Y+ H++ E++G G I+ D Sbjct: 169 LA---PVAKSVTLIHRRDQFRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAII-FD 224 Query: 230 ENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFV 289 +E E +DVD+VIIS G ++ + K GV + +VN R+ET +PG++ Sbjct: 225 NRTKE----EKVLDVDSVIISIGYKGDLGNIPKWGVTM--KGRDIVVNGRMETNLPGVYA 278 Query: 290 AGN 292 G+ Sbjct: 279 GGD 281 >pir||D71200 probable glutamate synthase small chain - Pyrococcus horikoshii >gi|3258312|dbj|BAA30995.1| (AP000007) 476aa long hypothetical glutamate synthase small chain [Pyrococcus horikoshii] Length = 476 Score = 70.6 bits (170), Expect = 3e-11 Identities = 92/343 (26%), Positives = 147/343 (42%), Gaps = 56/343 (16%) Query: 4 VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63 VAVIG GPAG+ A + ++G V + + GG+L +GI PEF Sbjct: 157 VAVIGAGPAGLTCAAELAKMGYDVTIYEALHEPGGVL------AYGI---------PEF- 200 Query: 64 YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHAFE 123 +L + E++ + + I I R I P ++E A I AG + Sbjct: 201 -RLPKEILRKELKKLSILGVKIKTDHIVGRTVTI-PELLKEYDAIFIGTGAGTPKL---- 254 Query: 124 IGITGDRVAGIFTAGEAQT---LMDIY-------GIMPGREILIVGSGDVGLIMARRFAL 173 + I G + GI++A E T LM Y I+ G+ ++++G+G+ + AR Sbjct: 255 LKIPGINLNGIYSANEFLTRINLMKAYKFPEYDTPIIVGKRVIVIGAGNTAMDAARSALR 314 Query: 174 EGARVKAVIELMPYPGG------LARNVMILNDFNIPLYLSHKVVEIRG--KGRVQRVKI 225 GA V ++ Y G V + + VE G GRV+ VK Sbjct: 315 LGAEV-----IIAYRRGEEDMTARIEEVQHAKEEGVKFMFFVNPVEFIGDENGRVKAVKF 369 Query: 226 VKV-------DENLREIPGTEFWVDV--DTVIISAGLIPNVKLLTKVGVAIDPSTGGPI- 275 K+ R+I GT +V V DTV+I+ G PN +++ K + G I Sbjct: 370 EKMKPLEERDSRGKRKIIGTGEYVTVETDTVVIAIGQTPN-RIIWKTTPGLKVRENGTIV 428 Query: 276 VNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318 V++ L T++PG+F G+A+ V + G AA+ E++ Sbjct: 429 VDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHEYL 471 >sp|P75531|TRXB_MYCPN THIOREDOXIN REDUCTASE (TRXR) >gi|2146661|pir||S73917 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1674293|gb|AAB96239.1| (AE000058) thioredoxin reductase [Mycoplasma pneumoniae] >gi|2231181|gb|AAC45451.1| (U51988) thioredoxin reductase K04_orf315 [Mycoplasma pneumoniae] Length = 315 Score = 69.9 bits (168), Expect = 5e-11 Identities = 71/301 (23%), Positives = 142/301 (46%), Gaps = 36/301 (11%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCI---HPGFGIHYFKEEL 57 +YDVA++G GPAG+AA I + L++ +I+ + G ++ I +PG+ + + Sbjct: 15 IYDVAIVGAGPAGIAAGIYGKRANLNLAIIEGSTPGGKVVKTNIVENYPGY------KSI 68 Query: 58 TGPEFAYKLMNRLRDVE-VRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGA 116 TGP+ ++ N L D+E A ++++ +D ++ + AKT+IYA G Sbjct: 69 TGPDLGLEMYNHLIDLEPTFFYANLIKLDKAAD----TFILYLDDKTVVFAKTVIYATGM 124 Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176 ER ++G+ + + G + + + + + +VG G+ A + AL A Sbjct: 125 LER---KLGVA--KEDHFYGKGISYCAICDGSLYKDQVVGVVGGGN----SAIQEALYLA 175 Query: 177 RVKAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVK-VDEN 231 + + L+ G + LN N+ +L++ V E+ G + + + +D + Sbjct: 176 SMAKTVHLIHRREGFRADETALNKLRNLPNVVFHLNYTVKELLGNNTLNGIVLQNTLDHS 235 Query: 232 LREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAG 291 ++I D++ V G K + + + +DP G I N+++ET++ G+F AG Sbjct: 236 TKQI-------DLNCVFPYIGFESITKPVEHLNLKLDPQ-GFLITNEQMETSLKGLFAAG 287 Query: 292 N 292 + Sbjct: 288 D 288 >pir||D35156 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Eubacterium acidaminophilum Length = 315 Score = 69.9 bits (168), Expect = 5e-11 Identities = 82/328 (25%), Positives = 145/328 (44%), Gaps = 30/328 (9%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60 +YD+A+IG GPAG+AAA+ + I+I+ G I+ H E TGP Sbjct: 4 VYDLAIIGSGPAGLAAALYGARAKMKTIMIEGQKVGGQIV--ITHEVANYPGSVREATGP 61 Query: 61 EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120 ++ + + + +V++ I D++ ++KVI E +AK++I A GA R Sbjct: 62 SLIERMEEQANEF---GAEKVMDKIVDVDLDGKIKVIKGEK-AEYKAKSVILATGAAPRL 117 Query: 121 A---FEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177 A E +TG V+ T +A D+ E+ +VG GD + A A + Sbjct: 118 AGCPGEQELTGKGVSYCATC-DADFFEDM-------EVFVVGGGDTAVEEAMYLAKFARK 169 Query: 178 VKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPG 237 V V + + + + + EI+G G V+ V +NL Sbjct: 170 VTIVHRRDELRAAKSIQEKAFKNPKLDFMWNSAIEEIKGDGIVESA----VFKNLVTGET 225 Query: 238 TEFWVDVDT----VIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNA 293 TE++ + + + + G IP + K + +D G I +D ++T V G+F AG+ Sbjct: 226 TEYFANEEDGTFGIFVFIGYIPKSDVF-KGKITLD-DAGYIITDDNMKTNVDGVFAAGDI 283 Query: 294 LV--INDLVDYVVEQGELAAEGAKEFID 319 V + +V + G +AA A+++++ Sbjct: 284 RVKSLRQVVTACAD-GAIAATQAEKYVE 310 >gb|AAK42805.1| Mercuric reductase (Hg(II) reductase) (merA) [Sulfolobus solfataricus] Length = 453 Score = 69.9 bits (168), Expect = 5e-11 Identities = 87/346 (25%), Positives = 149/346 (42%), Gaps = 61/346 (17%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF----------GI 50 M D+ +IG G AG AA I+A ELG+ +++ + +GG C++ G + Sbjct: 1 MEDLVIIGYGAAGFAALIRANELGIKPVVVGYGE-IGG---TCVNVGCVPSKRMLRIGEL 56 Query: 51 HYFKEELTG----PEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRL---KVISPSGI- 102 + + ++ G PEF ++ V + ++IN DI+ ++ SP+ + Sbjct: 57 YNYSSKVIGKKLFPEFFQAFQDKAEIVNSLRKEKYEDVINSYDIKLKIGKAYFTSPNAVK 116 Query: 103 ---EEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREI---L 156 E I AK I A G+ I G G +T EA + P + I Sbjct: 117 VNGEIIEAKKFIIATGSSPNIP---NIKGLTEVGFWTNVEA--------LSPDKTISSLA 165 Query: 157 IVGSGDVGLIMARRFALEGARV-------KAVIELMPYPGGLARNVMILNDFNIPLYLSH 209 I+G + L A+ + G + + + P +N + ND +IP++ + Sbjct: 166 IIGGRALALEFAQMYKRLGVDTTILQRSGRILPDWEPEISLSVKNYLEEND-SIPIFTNV 224 Query: 210 KVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKL-LTKVGVAID 268 +V E+R KG ++ + E V+ D ++++ G PNV L L G+ ++ Sbjct: 225 RVKEVR-KGNGGKIIVTDKGE-----------VEADEILLATGRKPNVDLNLDAAGIELN 272 Query: 269 PSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGA 314 GG VN+ L T+ P +F AG+ + L QG +AAE A Sbjct: 273 -DKGGIKVNEELRTSNPNVFAAGDVIGGPMLEALAGRQGSIAAENA 317 >gb|AAA19188.1| (U10552) acetoin dehydrogenase [Klebsiella pneumoniae] Length = 439 Score = 69.9 bits (168), Expect = 5e-11 Identities = 87/350 (24%), Positives = 147/350 (41%), Gaps = 63/350 (18%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 YDV +IGGGP G AAI+A +LGL +L+ E +LGGI C++ +G K L G E Sbjct: 5 YDVLIIGGGPGGYVAAIRAGQLGLRTVLV-EKQHLGGI---CLN--WGCIPTKALLHGAE 58 Query: 62 FAY--------------------KLMNRLRDVEVRTSARVVEIINYSDIE-----KRLKV 96 A+ KL+ R V + +A V ++ + + RL+ Sbjct: 59 VAHTITHASQLGISVGEVNVDLQKLVQFSRTVSQQLTAGVAYLLKKNGVRVIDGTARLRG 118 Query: 97 ISPSGIE-------EIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 +E + RA +I A GAR R I G+ + F A + L Sbjct: 119 KGQITVEDARGEARDYRADHVILATGARPRALPGIAPDGEHIWTYFEALRPKLL------ 172 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYL-- 207 + +LI+GSG +G+ A + G +V V LA ++ + D + + Sbjct: 173 --PKSLLIIGSGAIGVEFASLYNDLGCKVTLV--------ELASQILPVEDAEVSAAVRK 222 Query: 208 --SHKVVEIRGKGRVQRVKIVKVDENLR---EIPGTEFWVDVDTVIISAGLIPNVKLLTK 262 + ++I + V +V++ D +R G E+ DV+ V+++ G+ PN++ L Sbjct: 223 SFEKRGIQIHTQTLVTQVQL--TDTGVRCTLNNTGGEYSQDVERVLLAVGVQPNIEDLGL 280 Query: 263 VGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE 312 + ++ G + T V G++ G+ L +G L E Sbjct: 281 ETLGVELDRGFIKTDAACRTNVFGLYAIGDVAGPPCLAHKASHEGVLCVE 330 >pir||JC4793 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Klebsiella pneumoniae >gi|945058|gb|AAB40885.1| (U30887) dihydrolipoamide dehydrogenase [Klebsiella pneumoniae] Length = 465 Score = 69.9 bits (168), Expect = 5e-11 Identities = 87/350 (24%), Positives = 147/350 (41%), Gaps = 63/350 (18%) Query: 2 YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61 YDV +IGGGP G AAI+A +LGL +L+ E +LGGI C++ +G K L G E Sbjct: 5 YDVLIIGGGPGGYVAAIRAGQLGLRTVLV-EKQHLGGI---CLN--WGCIPTKALLHGAE 58 Query: 62 FAY--------------------KLMNRLRDVEVRTSARVVEIINYSDIE-----KRLKV 96 A+ KL+ R V + +A V ++ + + RL+ Sbjct: 59 VAHTITHASQLGISVGEVNVDLQKLVQFSRTVSQQLTAGVAYLLKKNGVRVIDGTARLRG 118 Query: 97 ISPSGIE-------EIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 +E + RA +I A GAR R I G+ + F A + L Sbjct: 119 KGQITVEDARGEARDYRADHVILATGARPRALPGIAPDGEHIWTYFEALRPKLL------ 172 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYL-- 207 + +LI+GSG +G+ A + G +V V LA ++ + D + + Sbjct: 173 --PKSLLIIGSGAIGVEFASLYNDLGCKVTLV--------ELASQILPVEDAEVSAAVRK 222 Query: 208 --SHKVVEIRGKGRVQRVKIVKVDENLR---EIPGTEFWVDVDTVIISAGLIPNVKLLTK 262 + ++I + V +V++ D +R G E+ DV+ V+++ G+ PN++ L Sbjct: 223 SFEKRGIQIHTQTLVTQVQL--TDTGVRCTLNNTGGEYSQDVERVLLAVGVQPNIEDLGL 280 Query: 263 VGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE 312 + ++ G + T V G++ G+ L +G L E Sbjct: 281 ETLGVELDRGFIKTDAACRTNVFGLYAIGDVAGPPCLAHKASHEGVLCVE 330 >sp|P50971|TRXB_EUBAC THIOREDOXIN REDUCTASE (TRXR) >gi|1353197|gb|AAB93303.1| (L04500) thioredoxin reductase [Eubacterium acidaminophilum] Length = 315 Score = 69.9 bits (168), Expect = 5e-11 Identities = 82/328 (25%), Positives = 145/328 (44%), Gaps = 30/328 (9%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60 +YD+A+IG GPAG+AAA+ + I+I+ G I+ H E TGP Sbjct: 4 VYDLAIIGSGPAGLAAALYGARAKMKTIMIEGQKVGGQIV--ITHEVANYPGSVREATGP 61 Query: 61 EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120 ++ + + + +V++ I D++ ++KVI E +AK++I A GA R Sbjct: 62 SLIERMEEQANEF---GAEKVMDKIVDVDLDGKIKVIKGEK-AEYKAKSVILATGAAPRL 117 Query: 121 A---FEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177 A E +TG V+ T +A D+ E+ +VG GD + A A + Sbjct: 118 AGCPGEQELTGKGVSYCATC-DADFFEDM-------EVFVVGGGDTAVEEAMYLAKFARK 169 Query: 178 VKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPG 237 V V + + + + + EI+G G V+ V +NL Sbjct: 170 VTIVHRRDELRAAKSIQEKAFKNPKLDFMWNSAIEEIKGDGIVESA----VFKNLVTGET 225 Query: 238 TEFWVDVDT----VIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNA 293 TE++ + + + + G IP + K + +D G I +D ++T V G+F AG+ Sbjct: 226 TEYFANEEDGTFGIFVFIGYIPKSDVF-KGKITLD-DAGYIITDDNMKTNVEGVFAAGDI 283 Query: 294 LV--INDLVDYVVEQGELAAEGAKEFID 319 V + +V + G +AA A+++++ Sbjct: 284 RVKSLRQVVTACAD-GAIAATQAEKYVE 310 >sp|O66790|TRXB_AQUAE THIOREDOXIN REDUCTASE (TRXR) >gi|7427756|pir||B70345 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Aquifex aeolicus >gi|2983154|gb|AAC06756.1| (AE000693) thioredoxin reductase [Aquifex aeolicus] Length = 323 Score = 69.5 bits (167), Expect = 7e-11 Identities = 91/343 (26%), Positives = 143/343 (41%), Gaps = 54/343 (15%) Query: 1 MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGI-LPQCI--HPGFGIHYFKEEL 57 +YDV +IG GPAG AAI G +++ + G + + Q I +PG + Sbjct: 12 VYDVIIIGAGPAGTTAAIYTARAGWKTLVLYRAEADGALGVTQKIENYPG---------V 62 Query: 58 TGPEFAYKLMNRLRDVEVRTSARVVE-IINYSDIEKRLKVISPSGIEEIRAKTIIYAAGA 116 GP Y+L+ +R+ A V + +D+ K + E R KTII A+GA Sbjct: 63 PGPLSGYELLKIMREQAKSFGAEFVRGKVIATDLNSDPKKVYTIDGREFRGKTIIVASGA 122 Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMAR---RFA- 172 ER G G+ G + + ++G D + A RFA Sbjct: 123 MERANKFKGEEEFLGRGVSYCGVCDA-----AFFKDQPVAVIGDDDYAIEEAEFIARFAN 177 Query: 173 -----LEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVK--- 224 + G+++KA E++ + L N+ + L H+ +EI G V+ +K Sbjct: 178 KVFFVVPGSKIKAPPEVIEHFEKLP---------NVEILLRHRPIEIVGDQVVKGIKLKD 228 Query: 225 IVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTV 284 + K +E L E+ G I G P+V L +G +VN+ + T+V Sbjct: 229 LEKKEEKLLEVNG--------VFIFLGGTKPSVDFL--MGQVEMTEGDCIVVNEEMMTSV 278 Query: 285 PGIFVAGNALVINDLVDYVVEQGELAAEGAKEFIDNDGIRSRK 327 PG+F AG+ L N++ VV AA G K + D S K Sbjct: 279 PGVFAAGDVL-CNEVKQAVV----AAAMGCKAALAVDKFLSGK 316 >pir||T06332 ferric leghemoglobin reductase isoenzyme 2 precursor - soybean >gi|3309269|gb|AAC26053.1| (AF074940) ferric leghemoglobin reductase-2 precursor [Glycine max] Length = 500 Score = 69.1 bits (166), Expect = 9e-11 Identities = 91/350 (26%), Positives = 144/350 (41%), Gaps = 60/350 (17%) Query: 3 DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54 DV VIGGGP G AAIKA +LGL I++ LGG C++ G H + Sbjct: 38 DVVVIGGGPGGYVAAIKAAQLGLKTTCIEKRGTLGG---TCLNVGCIPSKALLHSSHMYH 94 Query: 55 E----------ELTGPEFAYKLMNRLRDVEVRTSARVVE------IINYSDIEKRLKVIS 98 E + + E M +D V + +E +NY ++ K++S Sbjct: 95 EAKHAFANHGVKFSSVEVDLPAMMAQKDKAVSNLTKGIEGLFKKNKVNY--VKGYGKLVS 152 Query: 99 PS---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149 PS G ++ K II A G+ + GIT D + + G A L +I Sbjct: 153 PSEVSVDTTEGGNTVVKGKHIIIATGSDVKSL--PGITIDEKKVVSSTG-ALALTEI--- 206 Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAV---IELMPYPGGLARNVM--ILNDFNIP 204 + ++++G+G +GL M + G+ + V E++P R L + Sbjct: 207 --PKRLIVIGAGYIGLEMGSVWGRLGSEITVVEFASEIVPTMDAEVRKQFQRSLEKQGMK 264 Query: 205 LYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIP-NVKL-LTK 262 L KVV + G ++ + G + ++ D V++SAG P +L L K Sbjct: 265 FKLKTKVVGVDTSGDGVKLTLEPA------AGGDQTTLEADVVLVSAGRTPFTAELGLDK 318 Query: 263 VGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE 312 +GV D G +VN+R T V G++ G+ + L E G E Sbjct: 319 IGVETD-KIGRILVNERFATNVSGVYAIGDVIPGPMLAHKAEEDGVACVE 367 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.322 0.144 0.412 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 150757199 Number of Sequences: 2977 Number of extensions: 6597085 Number of successful extensions: 19328 Number of sequences better than 1.0e-10: 69 Number of HSP's better than 0.0 without gapping: 5 Number of HSP's successfully gapped in prelim test: 64 Number of HSP's that attempted gapping in prelim test: 19141 Number of HSP's gapped (non-prelim): 76 length of query: 407 length of database: 189,106,746 effective HSP length: 55 effective length of query: 352 effective length of database: 156,189,961 effective search space: 54978866272 effective search space used: 54978866272 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.9 bits) S2: 166 (69.1 bits)