BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0184 (PAB0184) DE:PROBABLE MONOOXYGENASE
         (407 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75218 probable monooxygenase PAB0184 - Pyrococcus abyssi (...   806  0.0
pir||F72254 hypothetical protein TM1433 - Thermotoga maritima (s...   328  5e-89
pir||C75144 sarcosine oxidase, chain alpha (soxa) PAB0212 - Pyro...   190  2e-47
pir||H71183 probable D-nopaline dehydrogenase - Pyrococcus horik...   183  3e-45
gi|11497889 sarcosine oxidase, subunit alpha (soxA) [Archaeoglob...   173  4e-42
emb|CAB88983.1| (AL353864) putative oxidoreductase. [Streptomyce...   142  8e-33
pir||A83461 hypothetical protein PA1488 [imported] - Pseudomonas...   125  7e-28
pir||D71016 probable thioredoxin reductase - Pyrococcus horikosh...    94  2e-18
sp|O18480|DLHD_MANSE DIHYDROLIPOAMIDE DEHYDROGENASE (E3) >gi|226...    94  3e-18
pir||D75116 thioredoxin reductase (trxb) PAB0500 - Pyrococcus ab...    92  8e-18
pir||B82969 sarcosine oxidase alpha subunit PA5418 [imported] - ...    91  2e-17
pir||H72322 thioredoxin reductase - Thermotoga maritima (strain ...    87  4e-16
pir||D83627 alkyl hydroperoxide reductase subunit F PA0140 [impo...    85  1e-15
emb|CAC11966.1| (AL445065) NADH peroxidase related protein [Ther...    83  7e-15
sp|P80880|TRXB_BACSU THIOREDOXIN REDUCTASE (TRXR) (GENERAL STRES...    82  1e-14
pir||T34868 probable glutamate synthase small chain - Streptomyc...    82  1e-14
emb|CAC12113.1| (AL445066) probable thioredoxin reductase [Therm...    80  5e-14
sp|O32823|TRXB_LISMO THIOREDOXIN REDUCTASE (TRXR) >gi|2246749|gb...    79  1e-13
pir||F72705 probable thioredoxin reductase APE1061 - Aeropyrum p...    78  2e-13
dbj|BAB07290.1| (AP001519) thioredoxin reductase (NADPH) [Bacill...    78  2e-13
gi|11499149 thioredoxin reductase (trxB) [Archaeoglobus fulgidus...    78  2e-13
gi|11498012 NADH oxidase (noxA-3) [Archaeoglobus fulgidus] >gi|7...    77  3e-13
emb|CAA11554.1| (AJ223804) 2-oxoglutarate dehydrogenase, E3 subu...    77  4e-13
pir||B75551 glutamate synthase, small subunit - Deinococcus radi...    77  4e-13
gb|AAF34796.1|AF228640_1 (AF228640) lipoamide dehydrogenase prec...    77  4e-13
sp|O06465|AHPF_XANCH ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi...    76  7e-13
pir||B75024 glutamate synthase small chain. PAB1214 - Pyrococcus...    76  9e-13
emb|CAB60740.1| (Y18636) thioredoxine reductase [Staphylococcus ...    76  9e-13
pir||F82936 thioredoxin reductase UU074 [imported] - Ureaplasma ...    75  1e-12
pir||H82668 subunit F of alkyl hydroperoxide reductase XF1531 [i...    75  1e-12
gb|AAG17888.1| (AF295339) dihydrolipoamide dehydrogenase precurs...    75  2e-12
pir||G70655 probable small subunit of NADH-dependent glutamate s...    74  3e-12
sp|O05204|AHPF_STAAU ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi...    74  3e-12
pir||D71076 probable glutamate synthase small chain - Pyrococcus...    74  3e-12
sp|P09832|GLTD_ECOLI GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN (GLU...    74  3e-12
dbj|BAA21091.1| (D86223) glutamate synthase [Pyrococcus sp.]           73  5e-12
gi|11497870 NADH oxidase (noxA-1) [Archaeoglobus fulgidus] >gi|7...    73  5e-12
dbj|BAB05342.1| (AP001512) unknown conserved protein [Bacillus h...    73  5e-12
pir||A49911 NADH oxidase (hydrogen peroxide-forming) (EC 1.6.-.-...    73  6e-12
sp|O82864|AHPF_PSEPU ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi...    73  6e-12
pir||H75052 NADH oxidase (noxa-1) PAB0936 - Pyrococcus abyssi (s...    73  6e-12
pir||G64491 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Methano...    72  1e-11
gi|4557525 dihydrolipoamide dehydrogenase precursor; E3 componen...    72  1e-11
gb|AAB01381.1| (L13761) dihydrolipoamide dehydrogenase [Homo sap...    72  1e-11
emb|CAB57297.1| (AJ243598) NADH oxidase [Sulfolobus solfataricus]      72  1e-11
gb|AAF21029.1|AF208523_2 (AF208523) HcnB [Pseudomonas aeruginosa]      72  1e-11
gb|AAF34795.1|AF228639_1 (AF228639) lipoamide dehydrogenase prec...    72  1e-11
gb|AAF79529.1|AC023673_17 (AC023673) F21D18.28 [Arabidopsis thal...    72  1e-11
pir||G83370 hydrogen cyanide synthase HcnB PA2194 [imported] - P...    72  1e-11
gb|AAG21579.1|AC051631_2 (AC051631) lipoamide dehydrogenase, put...    72  1e-11
sp|P09623|DLDH_PIG DIHYDROLIPOAMIDE DEHYDROGENASE, MITOCHONDRIAL...    71  2e-11
gb|AAA35764.1| (J03620) dihydrolipoamide dehydrogenase precursor...    71  2e-11
pir||E69194 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Methano...    71  2e-11
pir||H71171 probable NADH oxidase - Pyrococcus horikoshii >gi|32...    71  2e-11
sp|P50970|DLDH_ZYMMO DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONEN...    71  2e-11
gi|11498007 NADH oxidase (noxA-2) [Archaeoglobus fulgidus] >gi|7...    71  2e-11
emb|CAA11546.1| (AJ223781) thioredoxin reductase [Staphylococcus...    71  2e-11
pir||D72382 hypothetical protein TM0395 - Thermotoga maritima (s...    71  2e-11
gb|AAD52148.1|AF129406_2 (AF129406) alkyl hydroperoxide reductas...    71  2e-11
gb|AAK42391.1| Thioredoxin reductase (trxB-1) [Sulfolobus solfat...    71  3e-11
pir||D71200 probable glutamate synthase small chain - Pyrococcus...    71  3e-11
sp|P75531|TRXB_MYCPN THIOREDOXIN REDUCTASE (TRXR) >gi|2146661|pi...    70  5e-11
pir||D35156 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Eubacte...    70  5e-11
gb|AAK42805.1| Mercuric reductase (Hg(II) reductase) (merA) [Sul...    70  5e-11
gb|AAA19188.1| (U10552) acetoin dehydrogenase [Klebsiella pneumo...    70  5e-11
pir||JC4793 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Klebsi...    70  5e-11
sp|P50971|TRXB_EUBAC THIOREDOXIN REDUCTASE (TRXR) >gi|1353197|gb...    70  5e-11
sp|O66790|TRXB_AQUAE THIOREDOXIN REDUCTASE (TRXR) >gi|7427756|pi...    69  7e-11
pir||T06332 ferric leghemoglobin reductase isoenzyme 2 precursor...    69  9e-11

>pir||C75218 probable monooxygenase PAB0184 - Pyrococcus abyssi (strain Orsay)
           >gi|5457703|emb|CAB49194.1| (AJ248283) PROBABLE
           MONOOXYGENASE [Pyrococcus abyssi]
           Length = 407
           
 Score =  806 bits (2059), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60
           MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP
Sbjct: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60

Query: 61  EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120
           EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH
Sbjct: 61  EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120

Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180
           AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA
Sbjct: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180

Query: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF 240
           VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF
Sbjct: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF 240

Query: 241 WVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLV 300
           WVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLV
Sbjct: 241 WVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLV 300

Query: 301 DYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIKGENVRFVVPHYLSGDRDVWIYLRVSRP 360
           DYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIKGENVRFVVPHYLSGDRDVWIYLRVSRP
Sbjct: 301 DYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIKGENVRFVVPHYLSGDRDVWIYLRVSRP 360

Query: 361 MEDVRLEMPEIGKRMRLPIVKPSEMIRIKLRGKDVKGVDKITVRVVK 407
           MEDVRLEMPEIGKRMRLPIVKPSEMIRIKLRGKDVKGVDKITVRVVK
Sbjct: 361 MEDVRLEMPEIGKRMRLPIVKPSEMIRIKLRGKDVKGVDKITVRVVK 407


>pir||F72254 hypothetical protein TM1433 - Thermotoga maritima (strain MSB8)
           >gi|4981998|gb|AAD36503.1|AE001795_6 (AE001795)
           oxidoreductase, putative [Thermotoga maritima]
           Length = 403
           
 Score =  328 bits (833), Expect = 5e-89
 Identities = 184/406 (45%), Positives = 263/406 (64%), Gaps = 13/406 (3%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62
           DV VIG G AGMAAA+KA+E G  V+L++ ++  GGIL QCIH GFG+HYF++ELTGPE+
Sbjct: 4   DVMVIGAGAAGMAAALKAKEEGAEVLLVERDERTGGILNQCIHNGFGLHYFRQELTGPEY 63

Query: 63  AYKLMNRLRDVEVR--TSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120
           A +   ++  + +R  T+A V  +      ++R+ +++  GIEE+    ++YA GARER 
Sbjct: 64  AERFQEKMEKMGIRALTNAYVKRVE-----DRRVILVTEQGIEEVEVGALVYATGARERP 118

Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180
              + I GDR +GIFTAG AQ L++I   +PG+  LI+GSGD+GLIMARR  LEG  V  
Sbjct: 119 FGSLMIPGDRPSGIFTAGVAQRLINIENRLPGKRALILGSGDIGLIMARRLTLEGMEVVG 178

Query: 181 VIELMPYPGGLARNVM-ILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239
           V+E +PY GGL RNV+  L D+NIPLYLS  VVE+RG+ R++ V + KVDE  R IP TE
Sbjct: 179 VVERLPYAGGLLRNVIQCLEDYNIPLYLSSTVVEVRGRERLEEVVVAKVDEQFRPIPRTE 238

Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDL 299
               VDT+++S GLIP V+L+  + V  +P++ G  V++  +T+   IF AGN  VI DL
Sbjct: 239 RVFKVDTLVLSVGLIPQVELIENL-VVKNPTSRGVGVSNIGQTSRDWIFSAGNCTVIFDL 297

Query: 300 VDYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIKGENVRFVVPHYLSGDRDVWIYLRVSR 359
           VDYV  +GE A   A +F+  +  R +   R   G+NV  V P + +    + +YLRV +
Sbjct: 298 VDYVSYEGETAGRYAAKFVKGEIPREKIPVR--PGKNVMVVHPIWYTPAEPLTLYLRVKK 355

Query: 360 PMEDVRLEMPEIGKRMRLPIVKPSEMIRIKLRGKDVKGVDKITVRV 405
           PME  RL +    +      + PSEM+R+K+  +D++G+D+I V V
Sbjct: 356 PMEKGRLVVGRFAREFE--DLVPSEMLRVKISDRDLEGLDEIVVSV 399


>pir||C75144 sarcosine oxidase, chain alpha (soxa) PAB0212 - Pyrococcus abyssi
           (strain Orsay) >gi|5457744|emb|CAB49234.1| (AJ248284)
           sarcosine oxidase, subunit alpha (soxA) [Pyrococcus
           abyssi]
           Length = 481
           
 Score =  190 bits (479), Expect = 2e-47
 Identities = 119/318 (37%), Positives = 177/318 (55%), Gaps = 10/318 (3%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62
           D+ VIGGGPAGM AAI A + G  V+LIDEN  LGG L +  H  FG       + G + 
Sbjct: 121 DIIVIGGGPAGMMAAISAHDAGAKVVLIDENPMLGGQLVKQTHKFFGKRSQFAGVRGVKI 180

Query: 63  AYKLMNRL--RDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120
           A  L N +  R++EV      V I    + +  + +   S + E+  + II A GA E+ 
Sbjct: 181 AEILENEVKKRNIEVFLQTSAVGIFQDGNEKIVVGIRKESELIELHGRAIIVATGAMEK- 239

Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180
              +    + + GI+ AG  QTLM+ YG+ PG + LIVG+G+VGLI+A +    G +V+A
Sbjct: 240 --SVPFENNDLPGIYGAGAIQTLMNTYGVKPGEKALIVGAGNVGLILAYQLIQAGVKVEA 297

Query: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF 240
           ++E MP  GG   +   +    +P+   H ++   GK +V+R  + ++DEN R IPGTE 
Sbjct: 298 IVEAMPKIGGYFVHAAKVRRLGVPILTRHTILRAEGKEKVERAIVAQIDENWRPIPGTEK 357

Query: 241 WVDVDTVIISAGLIPNVKLLTKVGVAID--PSTGGPIV--NDRLETTVPGIFVAGNALVI 296
             DVD + I+ GL P+++LL + G  I      GG +   ++ LETTV GIFVAG+   I
Sbjct: 358 IFDVDLIAIAVGLRPSIELLQQAGCQIRYVRELGGHVAVRDEWLETTVRGIFVAGDTAGI 417

Query: 297 NDLVDYVVEQGELAAEGA 314
            +    ++E G++A   A
Sbjct: 418 EEATTAMLE-GKIAGIAA 434


>pir||H71183 probable D-nopaline dehydrogenase - Pyrococcus horikoshii
           >gi|3258180|dbj|BAA30863.1| (AP000007) 482aa long
           hypothetical D-nopaline dehydrogenase [Pyrococcus
           horikoshii]
           Length = 482
           
 Score =  183 bits (460), Expect = 3e-45
 Identities = 122/338 (36%), Positives = 185/338 (54%), Gaps = 14/338 (4%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62
           D+ V+GGGPAGM AAI A + G  VILIDE+  LGG L +  H  FG       + G + 
Sbjct: 122 DIIVVGGGPAGMMAAISASDTGAKVILIDESPMLGGQLVKQTHKFFGKRDQFAGIRGIKI 181

Query: 63  AYKLMNRLRDVE-VRTSARVVEIINYSDIEKRLK--VISPSGIEEIRAKTIIYAAGARER 119
           A  L   +   E ++   R   +  + D E++L   V   + + E + K +I A GA E+
Sbjct: 182 AEILRREIEKRENIKAYLRTSAVGIFQDGEEKLVIGVRKENELIEFKGKAVIVATGAMEK 241

Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179
               I    + + GI+ AG  QTLM+ YGI PG + LIVG+G+VGLI+A +      +V+
Sbjct: 242 ---TIPFENNDLPGIYGAGAIQTLMNTYGIKPGEKALIVGAGNVGLILAYQLLQANVQVQ 298

Query: 180 AVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239
           A++E MP  GG   +   +    +P+   H +++  G+ +V+R  + ++DEN   IPGTE
Sbjct: 299 AIVEAMPKIGGYFVHAAKVRRLGVPILTRHTILKAEGEEKVERAIVAEIDENWNPIPGTE 358

Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAID--PSTGGPI-VNDR-LETTVPGIFVAGNALV 295
              DVD + I+ GL P+++LL + G  I      GG + V DR +ETTV GIFVAG+   
Sbjct: 359 KIFDVDLIAIAVGLRPSIELLQQAGCQIKYVRELGGHVPVRDRWMETTVKGIFVAGDTAG 418

Query: 296 INDLVDYVVEQGELAAEGAKEFIDNDGIRSRKWTRLIK 333
           I +    ++E G++A   A   +   GI   +W + I+
Sbjct: 419 IEEATTAMLE-GKIAGLAAALRL---GIAGEEWVKEIE 452


>gi|11497889 sarcosine oxidase, subunit alpha (soxA) [Archaeoglobus fulgidus]
           >gi|7482953|pir||A69284 coenzyme F420--quinone
           oxidoreductase (EC 1.6.5.-) 56K chain - Archaeoglobus
           fulgidus >gi|2650363|gb|AAB90959.1| (AE001086) sarcosine
           oxidase, subunit alpha (soxA) [Archaeoglobus fulgidus]
           Length = 534
           
 Score =  173 bits (433), Expect = 4e-42
 Identities = 115/332 (34%), Positives = 174/332 (51%), Gaps = 11/332 (3%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62
           DV VIGGGP GM+AAI A + G  V+L+DEN +LGG L +  H  FG    +    G + 
Sbjct: 171 DVLVIGGGPGGMSAAINAGKYGAKVLLVDENPFLGGQLVKQTHRFFGSAKERAGTRGIKI 230

Query: 63  AYKL---MNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119
           A  L   +N + +VEVR   RV  I N      +        +  I+AK I+ A GA ER
Sbjct: 231 AGILEEELNSIENVEVRRETRVFGIYNGEAGAYQRLNDDEGKLLRIKAKKIVVATGAYER 290

Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179
                    + + G++ AG  QTLM++YGI PG   LIVGSG+VGLI+  +    G  V 
Sbjct: 291 TLI---FENNDLPGVYGAGGVQTLMNVYGIKPGNMGLIVGSGNVGLILTYQLMQAGVNVA 347

Query: 180 AVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239
           A++E MP  GG   +   +    +P+Y+ H +++  G+  V+   I ++D+  + IPGTE
Sbjct: 348 AIVEAMPRIGGYFVHAAKVRRLGVPIYVRHTILKAIGRKSVEGAVIAQLDDRWQPIPGTE 407

Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAID--PSTGG--PIVNDRLETTVPGIFVAGNALV 295
             +  D + ++ GL P  +LL + G  +   P  GG  P+     ET+V G++VAG+   
Sbjct: 408 KEIKCDFICVAVGLSPTHELLYQAGCEMKFVPELGGIVPLRTRFNETSVKGLYVAGDVAG 467

Query: 296 INDLVDYVVEQGELAAEGAKEFIDNDGIRSRK 327
           I +    ++E G +A   A   +   G  ++K
Sbjct: 468 IEEATAAIME-GRIAGIHAAVTLGYGGEEAKK 498


>emb|CAB88983.1| (AL353864) putative oxidoreductase. [Streptomyces coelicolor A3(2)]
           Length = 416
           
 Score =  142 bits (354), Expect = 8e-33
 Identities = 111/401 (27%), Positives = 175/401 (42%), Gaps = 25/401 (6%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62
           DV V+G GPAG+ AA +    G  V+L++     GG+   C H GFG       LTGP  
Sbjct: 7   DVLVVGAGPAGLTAAARLARTGARVVLLEREQSPGGVPRHCAHRGFGDR--PHALTGPAH 64

Query: 63  AYKLMNRLRDVEVRTSARVVEIINYSDIE--KRLKVISPSGIEEIRAKTIIYAAGARERH 120
           A      L D   R  A +   +   D    + L  + P G E + A+ ++ A GARER 
Sbjct: 65  A----RLLADAAARAGADLRTGVTALDWAGPRALTTVGPRGAETLAARAVVLATGARERP 120

Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180
                + G R AG++T GE Q  + +YG   G   +IVG+  V    A      GA V A
Sbjct: 121 RAARLVPGTRPAGVYTTGELQQAVHLYGQHIGTRAVIVGAEGVSHAAADTVRAAGADVLA 180

Query: 181 VI-ELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239
           ++ EL   P   A  +        P+    KV E+ G+GR+  V++       R   G  
Sbjct: 181 LVTELPQAPAAPAWALAARLRHRTPVLTGTKVTELLGRGRLSGVRV-------RHRDGRS 233

Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDL 299
             +  DTV+ +   +P+ +L  +  + +DP T GP V+  L T+ PG+F  G+ L   + 
Sbjct: 234 TVLACDTVVFTGDFVPDHELARRGALTLDPGTRGPAVDGALRTSRPGVFAVGSVLHAVES 293

Query: 300 VDYVVEQGELAAEGAKEFI-DNDGIRSRKW---TRLIKGENVRFVVPHYLSGDRDVWIYL 355
                 +G  AA   + ++ D        W     L+ G  +  + P+ ++ D  +   L
Sbjct: 294 AATAAREGAHAATAVRRWLQDGTDPGDPYWPGGVPLLAGPPLLRIAPNRVTPDDRLPYLL 353

Query: 356 RVSRPMEDVRLEMPEIGK-----RMRLPIVKPSEMIRIKLR 391
           R + P+    L + + G+     R  L    P   +++  R
Sbjct: 354 RTAVPLSHPALYVTQDGRPLHRERFHLGTAVPHRPLKLTAR 394


>pir||A83461 hypothetical protein PA1488 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9947442|gb|AAG04877.1|AE004577_12
           (AE004577) hypothetical protein [Pseudomonas aeruginosa]
           Length = 412
           
 Score =  125 bits (312), Expect = 7e-28
 Identities = 86/295 (29%), Positives = 140/295 (47%), Gaps = 14/295 (4%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDEND-YLGGILPQCIHPGFGIHYFKEELTGPE 61
           DVA++G GPAG+AAAI+ R  G++ + + E D   GGI   C HP FG+      LTGP 
Sbjct: 8   DVAIVGSGPAGLAAAIELRRQGVARVCVLERDGEAGGIPRHCAHPPFGLREHGRLLTGPA 67

Query: 62  FAYKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119
           +A + + +     V++R    VV +         L++ +P G   +RA  ++ A GARE 
Sbjct: 68  YAQRNVEQAERAGVDIRLRHSVVALAAAG----LLQLATPEGPRSLRATRVLLATGARET 123

Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179
                 + GDR  G+   G  Q  + + G+ P    LIVG+  V L         G R  
Sbjct: 124 PRSARLLGGDRPLGVINTGALQAYLYLQGLKPFERPLIVGTELVSLSAVMSCRRAGIRPV 183

Query: 180 AVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTE 239
           A++E            +      +P++ S +++EI G+GRV+  ++   D  +  I    
Sbjct: 184 AMLERNARATARWPLSLFPRLCGVPMHFSSELLEIEGRGRVEAARVRLGDGRVERIA--- 240

Query: 240 FWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNAL 294
                D +++S   +P   L+    + +DP++GGP ++     + P  F AGN L
Sbjct: 241 ----CDGILLSGRFVPESSLVRLSHLELDPASGGPRIDQFGRCSDPAYFAAGNLL 291


>pir||D71016 probable thioredoxin reductase - Pyrococcus horikoshii
           >gi|3257849|dbj|BAA30532.1| (AP000006) 336aa long
           hypothetical thioredoxin reductase [Pyrococcus
           horikoshii]
           Length = 336
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 100/337 (29%), Positives = 153/337 (44%), Gaps = 47/337 (13%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGG--ILPQCI--HPGFGIHYFKEE 56
           ++DV +IG GPAG  AAI A   GL  I+I ++  LGG   +   I  +PGF      E 
Sbjct: 23  VWDVIIIGAGPAGYTAAIYAARFGLDTIIITKD--LGGNMAITDLIENYPGF-----PEG 75

Query: 57  LTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLK------VISPSGIEEIRAKTI 110
           ++G E + K+ ++++   V     + E+I     E          V+  +  +E +AKTI
Sbjct: 76  ISGSELSKKMYDQVKKYGVEVI--IDEVIRIDPAECAYYEGPCNFVVKTANGKEYKAKTI 133

Query: 111 IYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYG-IMPGREILIVGSGDVGLIMAR 169
           I A GA  R   ++ + G++    FT           G +  G+E+++VG G+  L  A 
Sbjct: 134 IIAVGAEPR---KLNVPGEKE---FTGRGVSYCATCDGPLFVGKEVIVVGGGNTALQEAL 187

Query: 170 RFALEGARVKAVIELMPYPGGLARNVMILND----FNIPLYLSHKVVEIRGKGRVQRV-- 223
                G +V  V     +     R   IL D      IP  L+  V EI+G  +V+ V  
Sbjct: 188 YLHSIGVKVTLVHRRDKF-----RADKILQDRFKQAGIPAILNTVVTEIKGTNKVESVVL 242

Query: 224 KIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETT 283
           K VK  E + +         VD V I  G  P    +  +G+  +   G   V+  + T 
Sbjct: 243 KNVKTGETVEK--------KVDGVFIFIGYEPKTDFVKHLGITDE--YGYIPVDMYMRTK 292

Query: 284 VPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFIDN 320
           VPGIF AG+   +   +   V QG +AA  AKEFI++
Sbjct: 293 VPGIFAAGDITNVFKQIAVAVGQGAIAANSAKEFIES 329


>sp|O18480|DLHD_MANSE DIHYDROLIPOAMIDE DEHYDROGENASE (E3) >gi|2267131|gb|AAB88282.1|
           (AF008586) dihydrolipoamide dehydrogenase [Manduca
           sexta]
           Length = 497
           
 Score = 94.0 bits (230), Expect = 3e-18
 Identities = 96/351 (27%), Positives = 164/351 (46%), Gaps = 54/351 (15%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------------- 47
           D+ VIG GP G  AAIKA +LG+ V+ +++   LGG    C++ G               
Sbjct: 32  DLVVIGAGPGGYVAAIKAAQLGMKVVSVEKEPSLGG---TCLNVGCIPSKALLHNTHLYH 88

Query: 48  FGIHYFKE---ELTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLK----VISPS 100
              H FK    E    +F +K M   +   V+     + ++   +  K ++    +++P+
Sbjct: 89  MAKHDFKHRGIETGEVKFNFKAMMDYKVNAVKALTGGIAMLFQKNKVKLVRGAGTIVAPN 148

Query: 101 --------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPG 152
                   G+E +  K I+ A G+ E   F  G+T D    I T+  A +L  +      
Sbjct: 149 KVEVKGEKGVETVNTKNILIATGS-EVTPFP-GVTFDE-KQIITSTGALSLESV-----P 200

Query: 153 REILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNI------PLY 206
           +++L++G+G +GL +   +   GA V A IE +   GG+  ++ +  D+ I         
Sbjct: 201 KKMLVIGAGVIGLELGSVYQRLGADVTA-IEFLGSIGGIGIDMEVSKDYRILAKQGMKFK 259

Query: 207 LSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTKVG 264
           L  KV+ ++ +G   +V+ V ++       G +  +D D V+IS G  P  K   L KVG
Sbjct: 260 LETKVLGVKKEGSTVKVEDVSIE---GAKGGNKETMDCDVVLISIGRRPYTKDLGLDKVG 316

Query: 265 VAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAK 315
           +A+D   G   VN++ +TTVPGI+  G+ +    L     ++G +  EG K
Sbjct: 317 IALD-DRGRVPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIK 366


>pir||D75116 thioredoxin reductase (trxb) PAB0500 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458156|emb|CAB49645.1| (AJ248285)
           thioredoxin reductase (trxB) [Pyrococcus abyssi]
           Length = 345
           
 Score = 92.4 bits (226), Expect = 8e-18
 Identities = 100/334 (29%), Positives = 151/334 (44%), Gaps = 41/334 (12%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGG--ILPQCI--HPGFGIHYFKEE 56
           ++DV +IG GPAG  AAI A   GL  I+I ++  LGG   +   I  +PGF      E 
Sbjct: 32  VWDVIIIGAGPAGYTAAIYAARFGLDTIIITKD--LGGNMAITDLIENYPGF-----PEG 84

Query: 57  LTGPEFAYKLMNRLRDVEVRTSARVVEIIN-----YSDIEKRLKVISPSGIEEIRAKTII 111
           ++G E A ++   ++   V      V  I+     Y +   + +V + +G +E + KTII
Sbjct: 85  ISGSELAKRMYEHVKKYGVDVIFDEVVRIDPAECAYYEGPCQFEVKTANG-KEYKGKTII 143

Query: 112 YAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYG-IMPGREILIVGSGDVGLIMARR 170
            A GA  R   ++ + G++    FT           G +  G+E+++VG G+  L  A  
Sbjct: 144 IAVGAEPR---KLHVPGEKE---FTGRGVSYCATCDGPLFVGKEVIVVGGGNTALQEALY 197

Query: 171 FALEGARVKAVIELMPYPGGLARNVMILND----FNIPLYLSHKVVEIRGKGRVQRVKIV 226
               G +V  V     +     R   IL D      IP  L+  V EIRG  +V+ V + 
Sbjct: 198 LHSIGVKVTLVHRRDKF-----RADKILQDRLKQAGIPTILNTVVTEIRGTNKVESVVLK 252

Query: 227 KVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPG 286
            V        G  F   VD V I  G  P    +  +G+  +   G   V+  + T VPG
Sbjct: 253 NVKT------GETFEKKVDGVFIFIGYEPKTDFVKHLGITDE--YGYIKVDMYMRTKVPG 304

Query: 287 IFVAGNALVINDLVDYVVEQGELAAEGAKEFIDN 320
           IF AG+   +   +   V QG +AA  AKEFI++
Sbjct: 305 IFAAGDITNVFKQIAVAVGQGAIAANSAKEFIES 338


>pir||B82969 sarcosine oxidase alpha subunit PA5418 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9951745|gb|AAG08803.1|AE004954_5 (AE004954)
           sarcosine oxidase alpha subunit [Pseudomonas aeruginosa]
           Length = 1005
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 81/301 (26%), Positives = 130/301 (42%), Gaps = 40/301 (13%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEF 62
           DV V+G GPAG+AAA+ A   G  VIL DE +  GG L             +E L G   
Sbjct: 172 DVLVVGAGPAGLAAALAAARSGARVILADEQEEFGGSLLDT----------RETLDGKPA 221

Query: 63  AYKLMNRLRDVE--------VRTSARVVEIINYSDIEKR----LKVISPSG-----IEEI 105
           A  + + + +++         R++       N+  I +R    L  ++P G     +  +
Sbjct: 222 AEWVADAVAELQGLPEVILLPRSTVNGYHDHNFLTIHERRTDHLGEVAPLGQVRQRVHRV 281

Query: 106 RAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGL 165
           RAK ++ AAGA ER    +    + + G   AG   T +  YG+ PG+++++  + D   
Sbjct: 282 RAKRVVLAAGAHER---PLVYGNNDLPGNMLAGAVSTYVRRYGVAPGKKLVLATNNDYAY 338

Query: 166 IMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKI 225
            +A  +   G +V A+ +    P G    V       + +     V+E RG  RV   K+
Sbjct: 339 RVALDWQEAGLQVVAIADARANPRG--EWVEEARQRGMRVITGSSVIEARGGKRVSGAKV 396

Query: 226 VKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVP 285
            ++D       G E W+D D +  S G  P V L + +G       G P   + +   VP
Sbjct: 397 ARIDLQAMRASGGE-WLDCDLIASSGGYSPVVHLASHLG-------GKPEWREEILAFVP 448

Query: 286 G 286
           G
Sbjct: 449 G 449


>pir||H72322 thioredoxin reductase - Thermotoga maritima (strain MSB8)
           >gi|4981404|gb|AAD35951.1|AE001753_7 (AE001753)
           thioredoxin reductase [Thermotoga maritima]
           Length = 317
           
 Score = 87.0 bits (212), Expect = 4e-16
 Identities = 88/318 (27%), Positives = 146/318 (45%), Gaps = 28/318 (8%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILID---ENDYLGGILPQCIHPGFGIHYFKEELT 58
           YD+ V+GGGPAG+ +AI AR  GLSV++++   E  Y+        +PGF        ++
Sbjct: 18  YDIVVVGGGPAGLTSAIYARRAGLSVLVVEKAIEGGYVNLTHLVENYPGF------PAIS 71

Query: 59  GPEFAYKLMNRLRDVEVRT-SARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117
           G E A K             +A VV++    +++   KV+     + I A  +I A GA 
Sbjct: 72  GEELASKFKEHAEKFGADIYNAEVVKL----EVQGDKKVVELDDGKRIEAPVVIVATGAN 127

Query: 118 ERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177
            +   ++ + G++    F  G +        +  G+++++VG GD     +   +    +
Sbjct: 128 PK---KLNVPGEK--EFFGKGVSYCATCDGYLFAGKDVIVVGGGDSACDESIFLSNIVNK 182

Query: 178 VKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPG 237
           +  +  L            +LN+  I +  +  V EIRGK +V+ V I    EN++   G
Sbjct: 183 ITMIQLLETLTAAKVLQERVLNNPKIEVIYNSTVREIRGKDKVEEVVI----ENVK--TG 236

Query: 238 TEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVIN 297
               +  D V I  GL PN KLL  + V +DP  G  I ++ +ET+V GI+  G+    N
Sbjct: 237 ETKVLKADGVFIFIGLDPNSKLLEGL-VELDP-YGYVITDENMETSVKGIYAVGDVRKKN 294

Query: 298 -DLVDYVVEQGELAAEGA 314
              +   V  G +A E A
Sbjct: 295 LRQIVTAVADGAIAVEHA 312


>pir||D83627 alkyl hydroperoxide reductase subunit F PA0140 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9945970|gb|AAG03530.1|AE004452_2 (AE004452) alkyl
           hydroperoxide reductase subunit F [Pseudomonas
           aeruginosa]
           Length = 521
           
 Score = 85.0 bits (207), Expect = 1e-15
 Identities = 81/304 (26%), Positives = 144/304 (46%), Gaps = 33/304 (10%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           +DV V+GGGPAG AAAI A   G+   +  E  + G +L       F      +E  GP+
Sbjct: 212 FDVLVVGGGPAGAAAAIYAARKGIRTGVAAER-FGGQVLDTMAIENF---ISVQETEGPK 267

Query: 62  FAYKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119
            A  L   +R  +V++    R  +++   +  +  +V   SG   ++AKT+I A GAR R
Sbjct: 268 LARALEEHVRHYEVDIMNLQRASKLVPAKNAGELHEVRFESG-GSLKAKTLILATGARWR 326

Query: 120 HAFEIGITGD---RVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176
              E+G+ G+   +  G+              +  G+ + ++G G+ G+      A++ A
Sbjct: 327 ---EMGVPGEQEYKAKGVCFCPHCDG-----PLFKGKRVAVIGGGNSGV----EAAIDLA 374

Query: 177 RVKAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENL 232
            + A + L+ +   L  + ++        N+ +  S    E++G G+ +   +V  D N 
Sbjct: 375 GIVAHVTLLEFDSKLRADAVLQRKLYSLPNVEVITSALTSEVKGDGQ-KVTGLVYKDRNS 433

Query: 233 REIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292
            E       ++++ + +  GL+PN + L K  V + P  G  IV+ R ET++PGIF AG+
Sbjct: 434 EEFKS----IELEGIFVQIGLLPNTEWL-KGSVELSP-RGEIIVDARGETSLPGIFAAGD 487

Query: 293 ALVI 296
              +
Sbjct: 488 VTTV 491


>emb|CAC11966.1| (AL445065) NADH peroxidase related protein [Thermoplasma
           acidophilum]
           Length = 435
           
 Score = 82.7 bits (201), Expect = 7e-15
 Identities = 81/309 (26%), Positives = 147/309 (47%), Gaps = 42/309 (13%)

Query: 3   DVAVIGGGPAGMAAAIKARELG--LSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60
           D+ VIGGG AGMAAA KA+ +    +V +I+   ++     +C     GI YF + + G 
Sbjct: 2   DIVVIGGGAAGMAAASKAKRVNKDANVTVIESGSFVS--YAEC-----GIPYFLQGIVGK 54

Query: 61  EFAYKLMNRLRDVEVRTSARVVEIINYSDIEK----RLKVISPSGIEEIRAKTIIYAAGA 116
             A  L++    +E  T  R +++I    ++K     L ++  +G   ++   +I A G+
Sbjct: 55  --AEDLLH--YPLEEFTEKRGIKVITGRVVKKIDTASLSLVLDNG-SAVKFDRLIIATGS 109

Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPG-REILIVGSGDVGLIMARRFALEG 175
           R R      I     +G+F     ++ + +   + G R I I+G+G +G+ +A      G
Sbjct: 110 RPR------IPDGIASGVFGLRSLESAIRLKEAIDGSRTITIIGAGVLGVELASTLTEAG 163

Query: 176 ARVKAVIELMPYPGGLARNV-MILNDF---NIPLYLSHKVVEIRGKGRVQRVKIVKVDEN 231
            RVK + +       L  ++  ILND+    + +  S   VEI+ KG         VD++
Sbjct: 164 KRVKVISKYDRVMPQLDPDMGKILNDYFSSKVEVEFSSTPVEIK-KGEDGFAVKTTVDDH 222

Query: 232 LREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAG 291
           +            D VI + G++PN  +    G+ +D   G  I ++ +ET++PGI+ AG
Sbjct: 223 VS-----------DVVIAAVGIVPNSNIAVDAGIKVD-QRGAIITDEHMETSIPGIYAAG 270

Query: 292 NALVINDLV 300
           +   + +++
Sbjct: 271 DVATVKNII 279


>sp|P80880|TRXB_BACSU THIOREDOXIN REDUCTASE (TRXR) (GENERAL STRESS PROTEIN 35) (GSP35)
           >gi|7427754|pir||A69727 thioredoxin reductase (NADPH)
           (EC 1.6.4.5) - Bacillus subtilis
           >gi|1945648|emb|CAB08055.1| (Z94043) hypothetical
           protein [Bacillus subtilis] >gi|2635992|emb|CAB15484.1|
           (Z99121) thioredoxin reductase [Bacillus subtilis]
           Length = 316
           
 Score = 81.9 bits (199), Expect = 1e-14
 Identities = 89/333 (26%), Positives = 151/333 (44%), Gaps = 46/333 (13%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQC----IHPGFGIHYFKEE 56
           +YDV +IG GPAGM AA+      LS ++I E    GG +        +PGF      E 
Sbjct: 6   IYDVIIIGAGPAGMTAAVYTSRANLSTLMI-ERGIPGGQMANTEDVENYPGF------ES 58

Query: 57  LTGPEFAYKLMNRLRDVEVRTS-ARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAG 115
           + GPE + K+    +      +   + E+I+     K  KV+  +G +E +A+ +I AAG
Sbjct: 59  ILGPELSNKMFEHAKKFGAEYAYGDIKEVID----GKEYKVVK-AGSKEYKARAVIIAAG 113

Query: 116 ARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGL---IMARRFA 172
           A  +   +IG+ G++  G    G +   +       G+E+++VG GD  +   +   RFA
Sbjct: 114 AEYK---KIGVPGEKELG--GRGVSYCAVCDGAFFKGKELVVVGGGDSAVEEGVYLTRFA 168

Query: 173 LEGARVKAVIELMPYPGGLARNVMILNDFN---IPLYLSHKVVEIRGK-GRVQRVKIVKV 228
            +   V    +L       A++++    F+   +    +  V EI  + G+V  V +V  
Sbjct: 169 SKVTIVHRRDKLR------AQSILQARAFDNEKVDFLWNKTVKEIHEENGKVGNVTLVDT 222

Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288
                 + G E     D V I  G++P  K    +G+  +   G    NDR+ET V GIF
Sbjct: 223 ------VTGEESEFKTDGVFIYIGMLPLSKPFENLGITNE--EGYIETNDRMETKVEGIF 274

Query: 289 VAGN--ALVINDLVDYVVEQGELAAEGAKEFID 319
            AG+     +  +V      G +AA+  + +++
Sbjct: 275 AAGDIREKSLRQIVT-ATGDGSIAAQSVQHYVE 306


>pir||T34868 probable glutamate synthase small chain - Streptomyces coelicolor
           >gi|5738513|emb|CAB52860.1| (AL109849) putative
           glutamate synthase small subunit [Streptomyces
           coelicolor A3(2)]
           Length = 487
           
 Score = 81.9 bits (199), Expect = 1e-14
 Identities = 91/347 (26%), Positives = 143/347 (40%), Gaps = 57/347 (16%)

Query: 4   VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           VAVIG GPAG+AAA +    G +V + +  D +GG+L       +GI  FK E       
Sbjct: 147 VAVIGSGPAGLAAAQQLTRAGHTVAVYERADRVGGLLR------YGIPEFKMEKRHINRR 200

Query: 64  YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHAFE 123
            + M R      RT   +   +  +D++KR   +             + AAG+    A +
Sbjct: 201 IEQM-RAEGTRFRTGVEIGRDLKATDLKKRYDAV-------------VIAAGSTT--ARD 244

Query: 124 IGITGDRVAGIFTAGE----AQTLMDIYGIMP-----GREILIVGSGDVGLIMARRFALE 174
           + + G  + GI  A E    A  + +   + P     G+ ++++G GD G         +
Sbjct: 245 LPVPGRELNGIHQAMEYLPLANKVQEGDYVAPPITAEGKHVVVIGGGDTGADCVGTAHRQ 304

Query: 175 GARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRV----------- 223
           GA     +E+MP PG   R+ +       P+          G  RV  V           
Sbjct: 305 GAASVTQLEIMPRPGE-ERDAVRQPWPTFPMLYKVTSAHEEGGERVYAVSTTHFEGDEDG 363

Query: 224 --------KIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK---LLTKVGVAIDPSTG 272
                   ++  VD  L   PGTE  +    V ++ G     K   L+ + G+ +D    
Sbjct: 364 NVQWLHMSEVEFVDGKLTSKPGTERKIPAQLVTLAMGFTGTDKDNGLVDQFGLELDER-- 421

Query: 273 GPIVNDR-LETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318
           G I  D   +T VPG+FVAG+A     L+ + + +G  AA GA  F+
Sbjct: 422 GNIARDADFQTNVPGVFVAGDAGRGQSLIVWAIAEGRSAARGADRFL 468


>emb|CAC12113.1| (AL445066) probable thioredoxin reductase [Thermoplasma
           acidophilum]
           Length = 319
           
 Score = 80.0 bits (194), Expect = 5e-14
 Identities = 78/292 (26%), Positives = 130/292 (43%), Gaps = 21/292 (7%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           +DV ++G G AG +AA+ A   G SV ++D+    GG+  +   P    +   + + G E
Sbjct: 17  FDVVIVGAGAAGFSAAVYAARSGFSVAILDK-AVAGGLTAEA--PLVENYLGFKSIVGSE 73

Query: 62  FAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVIS-PSGIEEIRAKTIIYAAGARERH 120
            A     +L        A++ E +    I+K        +  +   AK +I   G   +H
Sbjct: 74  LA-----KLFADHAANYAKIREGVEVRSIKKTQGGFDIETNDDTYHAKYVIITTGTTHKH 128

Query: 121 AFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVKA 180
              +G+ G+  +  F  G +        +  G+ ++ +G G+ G I A   + E  +   
Sbjct: 129 ---LGVKGE--SEYFGKGTSYCSTCDGYLFKGKRVVTIGGGNSGAIAAISMS-EYVKNVT 182

Query: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEF 240
           +IE MP        V  +   NIP  ++ +V EI G G+  +V  VK  +      G E 
Sbjct: 183 IIEYMPKYMCENAYVQEIKKRNIPYIMNAQVTEIVGDGK--KVTGVKYKD---RTTGEEK 237

Query: 241 WVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292
            ++ D V I  GLIP    L   GV +D   G  +V+ R  T+VPG++ AG+
Sbjct: 238 LIETDGVFIYVGLIPQTSFLKDSGVKLD-ERGYIVVDSRQRTSVPGVYAAGD 288


>sp|O32823|TRXB_LISMO THIOREDOXIN REDUCTASE (TRXR) >gi|2246749|gb|AAB63804.1| (AF009622)
           thioredoxin reductase [Listeria monocytogenes]
           Length = 319
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 82/331 (24%), Positives = 140/331 (41%), Gaps = 42/331 (12%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCI----HPGFGIHYFKEE 56
           +YDV +IG GPAGM AA+      L  ++I E    GG +        +PGF      + 
Sbjct: 7   IYDVIIIGAGPAGMTAALYTSRADLDTLMI-ERGVPGGQMVNTAEVENYPGF------DS 59

Query: 57  LTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIE-----KRLKVISPSGIEEIRAKTII 111
           + GP+ + K+++  +      +        Y DI+     K  K ++ +G +  +A+ II
Sbjct: 60  ILGPDLSDKMLSGAKQFGAEYA--------YGDIKEVVDGKEFKTVT-AGSKTYKARAII 110

Query: 112 YAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRF 171
            A GA  R   ++G  G+    +   G +   +        RE+++VG GD  +      
Sbjct: 111 IATGAEHR---KLGAAGEE--ELSGRGVSYCAVCDGAFFKNRELIVVGGGDSAVEEGTYL 165

Query: 172 ALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKG-RVQRVKIVKVDE 230
                +V  V                  D  +    +  V EI G G +V   K+V    
Sbjct: 166 TRYADKVTIVHRRDKLRAQQILQDRAFKDEKVDFIWNSTVEEIVGDGKKVTGAKLVST-- 223

Query: 231 NLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVA 290
               + G+E  + VD V I  GL+P  K    +G+  D   G  + ++ + T +PGIF A
Sbjct: 224 ----VDGSESIMPVDGVFIYVGLVPLTKAFLNLGITDD--EGYIVTDEEMRTNLPGIFAA 277

Query: 291 GN--ALVINDLVDYVVEQGELAAEGAKEFID 319
           G+  A  +  +V      G LA + A+++++
Sbjct: 278 GDVRAKSLRQIVT-ATGDGGLAGQNAQKYVE 307


>pir||F72705 probable thioredoxin reductase APE1061 - Aeropyrum pernix  (strain
           K1) >gi|5104731|dbj|BAA80046.1| (AP000060) 343aa long
           hypothetical thioredoxin reductase [Aeropyrum pernix]
           Length = 343
           
 Score = 78.0 bits (189), Expect = 2e-13
 Identities = 91/346 (26%), Positives = 157/346 (45%), Gaps = 53/346 (15%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQC----IHPGFGIHYFKEEL 57
           YD  ++G GPAG++AAI      +S +++  +  +GG L        +PG G        
Sbjct: 25  YDTVIVGAGPAGLSAAIYTTRFLMSTLIVSMD--VGGQLNLTNWIDDYPGMG-------- 74

Query: 58  TGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKR----LKVISPSGIEEIRAKTIIYA 113
            G E A KL+   +       A++V  +    +++       V    G+ E++A+T+I A
Sbjct: 75  -GLE-ASKLVESFKSHAEMFGAKIVTGVQVKTVDRLDDGWFLVRGSRGL-EVKARTVILA 131

Query: 114 AGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGRE-ILIVGSGDVGLIMARRFA 172
            G+R R   ++G+ G+  A +   G +   +    +  G++ +++VG GD         A
Sbjct: 132 VGSRRR---KLGVPGE--AELAGRGVSYCSVCDAPLFKGKDAVVVVGGGD--------SA 178

Query: 173 LEGARVKA----VIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVK 224
           LEGA + +     + L+    G       + +     NI   L   V EIRG+ RV+ V 
Sbjct: 179 LEGALLLSGYVGKVYLVHRRQGFRAKPFYVEEARKKPNIEFILDSIVTEIRGRDRVESV- 237

Query: 225 IVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTV 284
           +VK      ++ G E  + VD + I  G  P  +L   +G+  D S G  +V++ + T++
Sbjct: 238 VVK-----NKVTGEEKELRVDGIFIEIGSEPPKELFEAIGLETD-SMGNVVVDEWMRTSI 291

Query: 285 PGIFVAGNALVINDLVDYVV---EQGELAAEGAKEFIDNDGIRSRK 327
           PGIF AG+   +      VV     G +AA  A  ++   G+   K
Sbjct: 292 PGIFAAGDCTSMWPGFRQVVTAAAMGAVAAYSAYTYLQEKGLYKPK 337


>dbj|BAB07290.1| (AP001519) thioredoxin reductase (NADPH) [Bacillus halodurans]
           Length = 315
           
 Score = 78.0 bits (189), Expect = 2e-13
 Identities = 79/327 (24%), Positives = 144/327 (43%), Gaps = 34/327 (10%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQC----IHPGFGIHYFKEE 56
           +YDV + G GPAGM AA+      LS +++ E    GG +        +PGF      + 
Sbjct: 7   VYDVVIAGAGPAGMTAAVYTSRANLSTVMV-ERGVPGGQMANTEDVENYPGF------DH 59

Query: 57  LTGPEFAYKLMNRLRDVEVRTS-ARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAG 115
           + GPE + K+    +      +   + EII+  D++     +  +G +E +A+ +I A G
Sbjct: 60  ILGPELSTKMFEHAKKFGAEYAYGDIKEIIDQGDLK-----LVKAGNKEYKARAVIVATG 114

Query: 116 ARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEG 175
           A  +   ++G+ G++   +   G +   +       G+E+++VG GD  +  A       
Sbjct: 115 AEYK---KLGVPGEK--ELSGRGVSYCAVCDGAFFKGKELVVVGGGDSAVEEAVYLTRFA 169

Query: 176 ARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRG-KGRVQRVKIVKVDENLRE 234
           ++V  +                 ++  I     H V +I G  G+V  V I    E+ + 
Sbjct: 170 SKVTIIHRRDQLRAQKILQQRAFDNDKIEFIWDHVVKQINGTDGKVSSVTI----EHAKT 225

Query: 235 IPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNA- 293
               +F    D V I  G++P  + +  + +  D   G  + N+ +ET+VPGIF AG+  
Sbjct: 226 GEQQDF--KTDGVFIYIGMLPLNEAVKNLNILND--EGYIVTNEEMETSVPGIFAAGDVR 281

Query: 294 -LVINDLVDYVVEQGELAAEGAKEFID 319
              +  +V      G LAA+  + +I+
Sbjct: 282 EKSLRQIVT-ATGDGSLAAQNVQHYIE 307


>gi|11499149 thioredoxin reductase (trxB) [Archaeoglobus fulgidus]
           >gi|7427758|pir||A69444 thioredoxin reductase (NADPH)
           (EC 1.6.4.5) - Archaeoglobus fulgidus
           >gi|2649006|gb|AAB89692.1| (AE000995) thioredoxin
           reductase (trxB) [Archaeoglobus fulgidus]
           Length = 300
           
 Score = 77.6 bits (188), Expect = 2e-13
 Identities = 80/299 (26%), Positives = 138/299 (45%), Gaps = 35/299 (11%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGI-LPQCI--HPGFGIHYFKEEL 57
           MYDVA+IGGGPAG+ AA+ +   GL  +  +  D +  + L   I  +PGF       E 
Sbjct: 1   MYDVAIIGGGPAGLTAALYSARYGLKTVFFETVDPVSQLSLAAKIENYPGF-------EG 53

Query: 58  TGPEFAYKLMNRLRDVEVRTSA--RVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAG 115
           +G E    L+ ++++  V+  A  ++ ++       +   VI+  G  E  AK II A G
Sbjct: 54  SGME----LLEKMKEQAVKAGAEWKLEKVERVERNGETFTVIAEGG--EYEAKAIIVATG 107

Query: 116 ARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEG 175
            + +   E GI G+  +     G +           G+++++ GSG   +  A      G
Sbjct: 108 GKHK---EAGIEGE--SAFIGRGVSYCATCDGNFFRGKKVIVYGSGKEAIEDAIYLHDIG 162

Query: 176 ARVKAVIELMPYPGGLARNVMI--LNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLR 233
             V  V      P   A   ++  +    IP++ S  + +I G G+V+  K+V  +   +
Sbjct: 163 CEVTIVSRT---PSFRAEKALVEEVEKRGIPVHYSTTIRKIIGSGKVE--KVVAYNREKK 217

Query: 234 EIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292
           E    EF ++ D + ++ G+ P   ++ ++GV  D S G   V+    T V G+F AG+
Sbjct: 218 E----EFEIEADGIFVAIGMRPATDVVAELGVERD-SMGYIKVDKEQRTNVEGVFAAGD 271


>gi|11498012 NADH oxidase (noxA-3) [Archaeoglobus fulgidus]
           >gi|7483900|pir||H69299 NADH oxidase (noxA-3) homolog -
           Archaeoglobus fulgidus >gi|2650233|gb|AAB90837.1|
           (AE001077) NADH oxidase (noxA-3) [Archaeoglobus
           fulgidus]
           Length = 551
           
 Score = 77.3 bits (187), Expect = 3e-13
 Identities = 78/309 (25%), Positives = 145/309 (46%), Gaps = 26/309 (8%)

Query: 3   DVAVIGGGPAGMAAA--IKARELGLSVILIDENDYLGGILPQCIHPGF------GIHYFK 54
           +V VIGGG AG+ AA  I+ ++   S+ +++   Y+   L +C  P +       +   +
Sbjct: 2   NVVVIGGGAAGLKAASRIRRKDGDASITVVEAGKYVS--LGRCGLPYYVGGLVHEVDNLR 59

Query: 55  EELTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAA 114
           E   G         +L++++V T     EI       K +K++     +E+    ++ A 
Sbjct: 60  ETTYGAVRDEAYFKKLKNIDVLTETVATEI---DRSRKTVKIVRNGSEDELNYDYLVIAT 116

Query: 115 GARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALE 174
           GAR       GI  + V  + +A EA+ +++++      + +++G+G +GL  A   AL+
Sbjct: 117 GARPAKPPIEGIEAEGVVTLTSAEEAEKIIEMWE-EGAEKAVVIGAGFIGLESAE--ALK 173

Query: 175 GARVKA-VIELMPY--PGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDEN 231
              ++  VIE+M    P  L R + +L    +  +L  K V +    RV+  KIV  D+ 
Sbjct: 174 NLDMEVTVIEMMDRVAPAMLDREMAVL----VENHLREKGVNVVTSTRVE--KIVSQDDK 227

Query: 232 LREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAG 291
           +R +         D V+++ G+ PN +L  K G+ I   TG   V++ + T+   I+  G
Sbjct: 228 VRAVIANGKEYPADVVVVATGIKPNSELAEKAGLKIG-ETGAIWVDEYMRTSDESIYAGG 286

Query: 292 NALVINDLV 300
           + +    LV
Sbjct: 287 DCVETTCLV 295


>emb|CAA11554.1| (AJ223804) 2-oxoglutarate dehydrogenase, E3 subunit [Arabidopsis
           thaliana]
           Length = 472
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 95/363 (26%), Positives = 153/363 (41%), Gaps = 61/363 (16%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54
           DV +IGGGP G  AAIKA +LGL    I++   LGG    C++ G           H + 
Sbjct: 10  DVVIIGGGPGGYVAAIKAAQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 66

Query: 55  E----------ELTGPEFAYKLMNRLRDVEVRTSARVVE------IINYSDIEKRLKVIS 98
           E          +++  E     M   +D  V+   R VE       +NY  ++   K +S
Sbjct: 67  EAKHVFANHGVKVSSVEVDLPAMLAQKDTAVKNLTRGVEGLFKKNKVNY--VKGYGKFLS 124

Query: 99  PSGIE---------EIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
           PS +           ++ K II A G+  +     GIT D    + + G A +L +I   
Sbjct: 125 PSEVSVDTIDGENVVVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLTEI--- 178

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAV---IELMPYPGGLARNVM--ILNDFNIP 204
              ++++++G+G +GL M   +   G+ V  V    +++P   G  R      L    + 
Sbjct: 179 --PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAADIVPAMDGEIRKQFQRSLEKQKMK 236

Query: 205 LYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVG 264
             L  KVV +   G   ++ IV+  E      G +  ++ D V++SAG  P    L    
Sbjct: 237 FMLKTKVVGVDSSGDGVKL-IVEPAEG-----GEQTTLEADVVLVSAGRTPFTSGLDLEK 290

Query: 265 VAIDPSTGGPI-VNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDN 320
           + ++   GG I VN+R  T V G++  G+ +    L     E G    E   G    +D 
Sbjct: 291 IGVETDKGGRILVNERFSTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDY 350

Query: 321 DGI 323
           D +
Sbjct: 351 DKV 353


>pir||B75551 glutamate synthase, small subunit - Deinococcus radiodurans
           (strain R1) >gi|6457850|gb|AAF09769.1|AE001880_6
           (AE001880) glutamate synthase, small subunit
           [Deinococcus radiodurans]
           Length = 488
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 91/353 (25%), Positives = 149/353 (41%), Gaps = 40/353 (11%)

Query: 4   VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           VAV+G GPAG+AAA +    G  V + ++ND +GG++       +GI  FK + +  +  
Sbjct: 146 VAVVGSGPAGLAAAQQLARAGHDVTVFEKNDRVGGLV------RYGIPDFKLDKSHIDRR 199

Query: 64  YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKV-ISPSGIEEIRAKTIIYAAGARERHAF 122
            + M +   V  RT   V +    S I    K  ++P+ + E +   ++ A G+      
Sbjct: 200 IEQM-QAEGVTFRTGVLVGDWDENSKITNLSKERVTPAELRE-QFDAVVLAGGSETPR-- 255

Query: 123 EIGITGDRVAGIFTAGEAQTLMDIYGI---------MPGREILIVGSGDVGLIMARRFAL 173
           ++   G  + GI  A E     +               G+ ++++G GD G         
Sbjct: 256 DLPAPGRELNGIHYAMEFLPQQNRVNAGDKFKGQIRADGKHVVVIGGGDTGSDCVGTSNR 315

Query: 174 EGARVKAVIELMPYPGGLARNVMILNDFNIPL--YLSHKVVEIR----------GK-GRV 220
            GA      E+MP P       +    + + L    SH+   +R          GK G+V
Sbjct: 316 HGAAGVTQFEVMPQPPEQENKPLTWPYWPMKLRTSTSHEEGAVREFAIATKEFIGKGGKV 375

Query: 221 QRVKIVKV---DENLREIPGTEFWVDVDTVIISAGLI-PNVKLLTKVGVAIDPS---TGG 273
             V+ V+V   D  L EIPG+E     D V+++ G   P   +L   GV  DP      G
Sbjct: 376 TGVRTVRVEMKDGKLEEIPGSEETHKADLVLLAMGFTNPMQSVLDAFGVDKDPRGNVLAG 435

Query: 274 PIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFIDNDGIRSR 326
              +    T+VPG+F AG+      LV + + +G  AA    +F+  + +  R
Sbjct: 436 TEEHGGYLTSVPGVFAAGDMRRGQSLVVWAIREGRQAARAVDQFLMGESVLPR 488


>gb|AAF34796.1|AF228640_1 (AF228640) lipoamide dehydrogenase precursor [Arabidopsis thaliana]
           Length = 507
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 95/363 (26%), Positives = 153/363 (41%), Gaps = 61/363 (16%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54
           DV +IGGGP G  AAIKA +LGL    I++   LGG    C++ G           H + 
Sbjct: 45  DVVIIGGGPGGYVAAIKAAQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 101

Query: 55  E----------ELTGPEFAYKLMNRLRDVEVRTSARVVE------IINYSDIEKRLKVIS 98
           E          +++  E     M   +D  V+   R VE       +NY  ++   K +S
Sbjct: 102 EAKHVFANHGVKVSSVEVDLPAMLAQKDTAVKNLTRGVEGLFKKNKVNY--VKGYGKFLS 159

Query: 99  PSGIE---------EIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
           PS +           ++ K II A G+  +     GIT D    + + G A +L +I   
Sbjct: 160 PSEVSVDTIDGENVVVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLTEI--- 213

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAV---IELMPYPGGLARNVM--ILNDFNIP 204
              ++++++G+G +GL M   +   G+ V  V    +++P   G  R      L    + 
Sbjct: 214 --PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAADIVPAMDGEIRKQFQRSLEKQKMK 271

Query: 205 LYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVG 264
             L  KVV +   G   ++ IV+  E      G +  ++ D V++SAG  P    L    
Sbjct: 272 FMLKTKVVGVDSSGDGVKL-IVEPAEG-----GEQTTLEADVVLVSAGRTPFTSGLDLEK 325

Query: 265 VAIDPSTGGPI-VNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDN 320
           + ++   GG I VN+R  T V G++  G+ +    L     E G    E   G    +D 
Sbjct: 326 IGVETDKGGRILVNERFSTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDY 385

Query: 321 DGI 323
           D +
Sbjct: 386 DKV 388


>sp|O06465|AHPF_XANCH ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi|2098747|gb|AAC45426.1|
           (U94336) alkyl hydroperoxide reductase subunit F
           [Xanthomonas campestris]
           Length = 530
           
 Score = 76.1 bits (184), Expect = 7e-13
 Identities = 77/301 (25%), Positives = 141/301 (46%), Gaps = 28/301 (9%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           +DV V+GGGPAG AAA+ A   G+   +  E  + G +L       F       E  GP+
Sbjct: 213 FDVLVVGGGPAGSAAAVYAARKGIRTGVAAER-FGGQVLDTMSIENF---ISVPETEGPK 268

Query: 62  FAYKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119
            A  L   +R  DV++    R  ++I  +  +  +++   +G   +++KT+I + GAR R
Sbjct: 269 MAAALEQHVRQYDVDIMNLQRAEQLIP-AGADGLIEIKLANG-ASLKSKTVILSTGARWR 326

Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179
                G    +  G+              +  G+ + ++G G+ G+      A++ A + 
Sbjct: 327 QMNVPGEDQYKNKGVAYCPHCDG-----PLFKGKRVAVIGGGNSGV----EAAIDLAGIV 377

Query: 180 AVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREI 235
           A + L+ +   L  + ++        N+ +  S +  E+ G G+ +   +V  D    +I
Sbjct: 378 AHVTLVEFDDKLRADEVLQRKLRSLHNVRIITSAQTTEVLGDGQ-KVTGLVYKDRTGGDI 436

Query: 236 PGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALV 295
                 ++++ V +  GL+PN + L +  VA+ P  G  IV+DR +T VPG+F AG+A  
Sbjct: 437 Q----HIELEGVFVQIGLLPNTEFL-RGTVALSP-RGEIIVDDRGQTDVPGVFAAGDATT 490

Query: 296 I 296
           +
Sbjct: 491 V 491


>pir||B75024 glutamate synthase small chain. PAB1214 - Pyrococcus abyssi
           (strain Orsay) >gi|5459146|emb|CAB50632.1| (AJ248288)
           GLUTAMATE SYNTHASE SMALL CHAIN. [Pyrococcus abyssi]
           Length = 475
           
 Score = 75.7 bits (183), Expect = 9e-13
 Identities = 93/345 (26%), Positives = 148/345 (41%), Gaps = 60/345 (17%)

Query: 4   VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           VAVIG GPAG+  A +  ++G  V + +     GG+L       +GI  F+      E  
Sbjct: 157 VAVIGAGPAGLTCAAELAKMGYEVTIFEALHEPGGVL------AYGIPEFR---LPKEIL 207

Query: 64  YKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHA 121
            K + +L+   VE++T   V   +             P  +EE  A  I   AG  +   
Sbjct: 208 RKELKKLKFLGVEIKTDHIVGRTVTI-----------PELLEEYDAIFISTGAGTPKL-- 254

Query: 122 FEIGITGDRVAGIFTAGEAQT---LMDIY-------GIMPGREILIVGSGDVGLIMARRF 171
             + I G  + GI++A E  T   LM  Y        I+ G+ ++++G+G+  +  AR  
Sbjct: 255 --LKIPGINLNGIYSANEFLTRINLMKAYKFPEYDTPIVVGKRVIVIGAGNTAMDAARSA 312

Query: 172 ALEGARVKAVIELMPYPGG------LARNVMILNDFNIPLYLSHKVVEIRG--KGRVQRV 223
              GA V     ++ Y  G          V    +  +        VE  G  +GRV+ V
Sbjct: 313 LRLGAEV-----IIAYRRGKEDMTARIEEVQHAKEEGVKFMFFVNPVEFIGDEEGRVKAV 367

Query: 224 KIVKV-------DENLREIPGTEFW--VDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGP 274
           K  K+           R+I GT  +  V+ DTVII+ G  PN K+L +    +     G 
Sbjct: 368 KFEKMKPLEERDKRGKRKIVGTGEYITVEADTVIIAIGQTPN-KILWRTTPGLKVREDGT 426

Query: 275 -IVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318
            IV++ L T++PG+F  G+A+     V   +  G  AA+   E++
Sbjct: 427 IIVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHEYL 471


>emb|CAB60740.1| (Y18636) thioredoxine reductase [Staphylococcus aureus]
           Length = 311
           
 Score = 75.7 bits (183), Expect = 9e-13
 Identities = 88/334 (26%), Positives = 144/334 (42%), Gaps = 48/334 (14%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIH----PGFGIHYFKEEL 57
           +D+A+IG GPAGM AA+ A    L  ++I E    GG +         PGF      E +
Sbjct: 6   FDIAIIGAGPAGMTAAVYASRANLKTVMI-ERGIPGGQMANTEEVENFPGF------EMI 58

Query: 58  TGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEK-----RLKVISPSGIEEIRAKTIIY 112
           TGP+ + K+    +        +   +  Y DI+        KVI+  G +E+ AK +I 
Sbjct: 59  TGPDLSTKMFEHAK--------KFGAVYQYGDIKSVEDKGEYKVIN-FGNKELTAKAVII 109

Query: 113 AAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGL---IMAR 169
           A GA  +   +IG+ G++  G    G +   +        + + ++G GD  +       
Sbjct: 110 ATGAEYK---KIGVPGEQELG--GRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLT 164

Query: 170 RFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGK-GRVQRVKIVKV 228
           +FA +   V    EL      + ++    ND  I    SH +  I  K G+V  V +   
Sbjct: 165 KFADKVTIVHRRDELRAQ--RILQDRAFKND-KIDFIWSHTLKSINEKDGKVGSVTLTST 221

Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288
            +      G+E   + D V I  G+ P       +G+  D   G  +  D + T+VPGIF
Sbjct: 222 KD------GSEETHEADGVFIYIGMKPLTAPFKDLGITND--VGYIVTKDDMTTSVPGIF 273

Query: 289 VAGNA--LVINDLVDYVVEQGELAAEGAKEFIDN 320
            AG+     +  +V      G +AA+ A E+I++
Sbjct: 274 AAGDVRDKGLRQIVT-ATGDGSIAAQSAAEYIEH 306


>pir||F82936 thioredoxin reductase UU074 [imported] - Ureaplasma urealyticum
           >gi|6899025|gb|AAF30479.1|AE002107_3 (AE002107)
           thioredoxin reductase [Ureaplasma urealyticum]
           Length = 309
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 85/333 (25%), Positives = 144/333 (42%), Gaps = 48/333 (14%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGG--ILPQCIHPGFGIHYFKEELT 58
           +YD+ +IG GPAG+AAA+ A+  GL+VI++ E  + GG   L   +    GI+     + 
Sbjct: 5   VYDLVIIGAGPAGLAAAVYAKRSGLNVIIV-EKQFPGGKIALTSNVENYLGIN----SIP 59

Query: 59  GPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARE 118
           GPE AYK+  ++ ++ V       + I+  +  K++K+ +    + +  KT+I A G   
Sbjct: 60  GPELAYKMYEQVLNLNVSIIYEAADEISLKEKYKKIKLTT----QTLITKTVIIATGTEN 115

Query: 119 RHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARV 178
           R    +G       GI              +   + + ++GSG+  +  A   A     V
Sbjct: 116 RRLNILGELEFENKGISYCAICDG-----PLYKNKAVSVIGSGNSAVEEAIYLATIAKEV 170

Query: 179 KAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGT 238
             +     +        +  N  NI +Y + +  E  G   ++ +K   +  N       
Sbjct: 171 HLIANKPQFKAEQQLVQIANNTPNIKIYYNKQTFEFFGHQFLEGLKFRDLITN------- 223

Query: 239 EFWVDVDTVIISA-----GLIPNVKLLTKVGVAIDPSTGGPIVNDR-LETTVPGIFVAGN 292
               +V T+ I A     GL+P+   +    + I     G I  D+ ++T+V GIF AG 
Sbjct: 224 ----EVTTLNIEANFTFIGLLPS--RINTNNLCIFNEVNGFITTDKNMQTSVCGIFAAG- 276

Query: 293 ALVINDLVDYVVEQ-------GELAAEGAKEFI 318
                D+VD  V Q       G +AA  AKE+I
Sbjct: 277 -----DIVDKNVRQIATATNDGVIAALYAKEYI 304


>pir||H82668 subunit F of alkyl hydroperoxide reductase XF1531 [imported] -
           Xylella fastidiosa (strain 9a5c)
           >gi|9106569|gb|AAF84340.1|AE003983_2 (AE003983) subunit
           F of alkyl hydroperoxide reductase [Xylella fastidiosa]
           Length = 571
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 78/307 (25%), Positives = 136/307 (43%), Gaps = 40/307 (13%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           +DV V+G GPAG AAA+ A   G+   L+ E  + G +L       F       E  GP 
Sbjct: 254 FDVLVVGAGPAGTAAAVYAARKGVRTGLVAER-FGGQVLDTMTIENF---ISVPETDGPR 309

Query: 62  FAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIR--------AKTIIYA 113
               L   LR  E       V+I+N   +E  L     +G  E+R        ++T+I +
Sbjct: 310 MVAALEQHLRQYE-------VDIMNLQRVE-TLVPAGENGFIEVRLASGASLSSRTVILS 361

Query: 114 AGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFAL 173
            GAR R     G    R  G+              +  G+ + ++G G+ G+      A+
Sbjct: 362 TGARWRQMNVPGEDEYRNKGVAYCPHCDG-----PLFKGKRVAVIGGGNSGV----EAAI 412

Query: 174 EGARVKAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVD 229
           + A + + + L+ +   L  + ++        N+ + +  +  E+RG G+ +   +V VD
Sbjct: 413 DLAGIASYVTLLEFDTKLRADEVLQRKLRSMSNVEVIMGAQTTEVRGDGK-KVTGLVYVD 471

Query: 230 ENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFV 289
            +     G  F + ++ V +  GL+PN + L K  V + P  G  +V++   T++PG+F 
Sbjct: 472 RS----TGGSFTLALEGVFVQIGLLPNTEWL-KGRVELSP-RGEIVVDECGHTSLPGVFA 525

Query: 290 AGNALVI 296
           AG+A  +
Sbjct: 526 AGDATTV 532


>gb|AAG17888.1| (AF295339) dihydrolipoamide dehydrogenase precursor [Solanum
           tuberosum]
           Length = 504
           
 Score = 74.9 bits (181), Expect = 2e-12
 Identities = 96/362 (26%), Positives = 148/362 (40%), Gaps = 63/362 (17%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54
           DV VIGGGP G  AAIKA +LGL    I++   LGG    C++ G           H F 
Sbjct: 42  DVVVIGGGPGGYVAAIKAAQLGLKTTCIEKRGTLGG---TCLNVGCIPSKALLHSSHMFH 98

Query: 55  E----------ELTGPEFAYKLMNRLRDVEVRTSARVVE------IINYSDIEKRLKVIS 98
           E          + +  E     M   +D  V    R +E       +NY  ++   K +S
Sbjct: 99  EAQHSFANHGVKFSSVEVDLPAMMGQKDKAVSNLTRGIEGLFKKNKVNY--VKGYGKFLS 156

Query: 99  PS---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
           PS         G   ++ K II A G+  +     GIT D    + + G A  L +I   
Sbjct: 157 PSEISVDTVEGGNSVVKGKNIIIATGSDVKGL--PGITIDEKKIVSSTG-ALALTEI--- 210

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAV---IELMPYPGGLARNVM--ILNDFNIP 204
              + ++++G+G +GL M   +   G+ V  V    +++P   G  R      L    + 
Sbjct: 211 --PKRLVVIGAGYIGLEMGSVWGRLGSEVTVVEFASDIVPTMDGEVRKQFQRALEKQKMK 268

Query: 205 LYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTK 262
             L+ KVV +   G   ++ +           G +  ++ D V++SAG +P      L  
Sbjct: 269 FMLNTKVVSVDATGDGVKLTLEP------SAGGDQTILEADVVLVSAGRVPFTSGLGLDT 322

Query: 263 VGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFID 319
           +GV  D   G  +VN+R  T VPG+   G+ +    L     E G    E   G +  +D
Sbjct: 323 IGVETD-KAGRILVNERFATNVPGVHAIGDVIPGPMLAHKAEEDGVACVEFIAGKEGHVD 381

Query: 320 ND 321
            D
Sbjct: 382 YD 383


>pir||G70655 probable small subunit of NADH-dependent glutamate synthase -
           Mycobacterium tuberculosis (strain H37RV)
           >gi|1781098|emb|CAB06232.1| (Z83864) gltD [Mycobacterium
           tuberculosis]
           Length = 488
           
 Score = 74.1 bits (179), Expect = 3e-12
 Identities = 85/349 (24%), Positives = 143/349 (40%), Gaps = 59/349 (16%)

Query: 4   VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           VAV+G GPAG+AAA +    G +V + +  D +GG+L       +GI  FK E    +  
Sbjct: 147 VAVVGSGPAGLAAAQQLTRAGHTVTVFEREDRIGGLLR------YGIPEFKMEKRHLDRR 200

Query: 64  YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAK--TIIYAAGARERHA 121
              M R    E R    V   I+                E++RA    ++ A GA     
Sbjct: 201 LDQM-RSEGTEFRPGVNVGVDIS---------------AEKLRADFDAVVLAGGATAWR- 243

Query: 122 FEIGITGDRVAGIFTA----------GEAQTLMDIYGIMP----GREILIVGSGDVGLIM 167
            E+ I G  + G+  A           E   ++D  G  P    G++++I+G GD G   
Sbjct: 244 -ELPIPGRELEGVHQAMEFLPWANRVQEGDDVLDEDGQPPITAKGKKVVIIGGGDTGADC 302

Query: 168 ARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLS-------HKVVEIRGK--- 217
                 +GA      E+MP P            + +   +S        +V  +  +   
Sbjct: 303 LGTVHRQGAIAVHQFEIMPRPPDARAESTPWPTYPLMYRVSAAHEEGGERVFSVNTEAFV 362

Query: 218 ---GRVQRVK---IVKVDENLREIPGTEFWVDVDTVIISAGLI--PNVKLLTKVGVAIDP 269
              GRV  ++   +  +D    ++ G++F ++ D V+++ G +      LLT +GV    
Sbjct: 363 GTDGRVSALRAHEVTMLDGKFVKVEGSDFELEADLVLLAMGFVGPERAGLLTDLGVKFT- 421

Query: 270 STGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318
             G     D  +T+VPG+FVAG+      L+ + + +G  AA     ++
Sbjct: 422 ERGNVARGDDFDTSVPGVFVAGDMGRGQSLIVWAIAEGRAAAAAVDRYL 470


>sp|O05204|AHPF_STAAU ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi|1916317|gb|AAB51152.1|
           (U92441) alkyl hydroperoxide reductase subunit F
           [Staphylococcus aureus]
           Length = 507
           
 Score = 74.1 bits (179), Expect = 3e-12
 Identities = 80/300 (26%), Positives = 140/300 (46%), Gaps = 37/300 (12%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYF--KEELTG 59
           YDV ++GGGPA  +AAI     GL   ++   D +GG     ++   GI  F   +E TG
Sbjct: 206 YDVLIVGGGPASGSAAIYTARKGLRTGIV--ADRIGG----QVNDTAGIENFITVKETTG 259

Query: 60  PEFAYKLMNRL--RDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117
            EF+  L   +   D++  T  R  +I      ++ +KV   +G   + +KT+I A GA 
Sbjct: 260 SEFSSNLAAHIDQYDIDAMTGIRATDI---EKTDEAIKVTLENG-AVLESKTVIIATGAG 315

Query: 118 ERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177
            R   ++ I G+    +   G A        +   +++ ++G G+ G+      A++ A 
Sbjct: 316 WR---KLNIPGEE--QLINKGVAFCPHCDGPLFENKDVAVIGGGNSGV----EAAIDLAG 366

Query: 178 VKAVIELMPYPGGL-ARNVM---ILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLR 233
           +   + L  +   L A NV+   + +  N+ +  + K  E+ G+  V  ++   ++    
Sbjct: 367 IVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMN---- 422

Query: 234 EIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDR-LETTVPGIFVAGN 292
              G E  +++D + +  GL+PN   L     A++ +  G IV DR   T VPGIF AG+
Sbjct: 423 --TGEEHLLNLDGIFVQIGLLPNTSWLND---AVELNERGEIVIDRNNNTNVPGIFAAGD 477


>pir||D71076 probable glutamate synthase small chain - Pyrococcus horikoshii
           >gi|3257287|dbj|BAA29970.1| (AP000004) 472aa long
           hypothetical glutamate synthase small chain [Pyrococcus
           horikoshii]
           Length = 472
           
 Score = 74.1 bits (179), Expect = 3e-12
 Identities = 92/342 (26%), Positives = 152/342 (43%), Gaps = 55/342 (16%)

Query: 4   VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           VAV+G GPAG+  A +  ++G  V + +     GG+L       +GI  F+      +  
Sbjct: 151 VAVVGAGPAGLTCAGELAKMGYKVTIFEALHKPGGVL------AYGIPEFRLPKEILDHE 204

Query: 64  YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHAFE 123
            K +  L  VE+RT   V + +   ++           ++E  A  I   AG  +     
Sbjct: 205 LKKLKML-GVEIRTDHVVGKTVTLDEL-----------LQEYDAVFIGTGAGTPKL---- 248

Query: 124 IGITGDRVAGIFTAGEAQT---LMDIYG-------IMPGREILIVGSGDVGLIMARRFAL 173
           + I G  +  I++A E  T   LM  Y        I  G++++++G+G+  +  AR    
Sbjct: 249 LNIPGILLDRIYSANEFLTRINLMKAYEFPEYDTPIAVGKKVIVIGAGNTAMDAARSALR 308

Query: 174 EGARVKAVIELMPYPGG----LARNVMILN--DFNIPLYLSHKVVEIRG--KGRVQRVKI 225
            GA V      + Y  G     AR   I +  +  +      + VE  G   GRV+ VK 
Sbjct: 309 LGAEVT-----IAYRRGREDMTAREEEIKHAEEEGVKFEFFLQPVEFIGDENGRVKAVKF 363

Query: 226 VKV-------DENLREIPGTEFWV--DVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIV 276
            +         +  R+I GT  +V  + DTVII+ GL PN K++T+ G       G  +V
Sbjct: 364 ERTKPLEERDSKGKRKIVGTGEYVTLEADTVIIAIGLEPN-KIITEDGRLKTNPDGTIVV 422

Query: 277 NDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318
           ++ L T++PG+F  G+A+     V   +  G+ AA+   E+I
Sbjct: 423 DENLMTSIPGVFAGGDAIRGEATVILAMGDGKRAAKAIDEYI 464


>sp|P09832|GLTD_ECOLI GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN (GLUTAMATE SYNTHASE BETA
           SUBUNIT) (NADPH-GOGAT) (GLTS BETA CHAIN)
           >gi|7448188|pir||G65112 glutamate synthase (NADPH) (EC
           1.4.1.13) small chain - Escherichia coli
           >gi|606152|gb|AAA58015.1| (U18997) glutamate synthase,
           small subunit [Escherichia coli]
           >gi|1789606|gb|AAC76245.1| (AE000400) glutamate
           synthase, small subunit [Escherichia coli K12]
           Length = 472
           
 Score = 73.7 bits (178), Expect = 3e-12
 Identities = 85/352 (24%), Positives = 149/352 (42%), Gaps = 65/352 (18%)

Query: 4   VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           VA+IG GPAG+A A      G+  ++ D +  +GG+L       FGI  FK E       
Sbjct: 149 VAIIGAGPAGLACADVLTRNGVKAVVFDRHPEIGGLLT------FGIPAFKLE------- 195

Query: 64  YKLMNRLRDVEVRTSARVVEIINYSDIEKRL--KVISPSGIEEIRAKTIIYAAGARERHA 121
                     EV T  R  EI     IE +L  +V     ++++ +       G     +
Sbjct: 196 ---------KEVMTRRR--EIFTGMGIEFKLNTEVGRDVQLDDLLSDYDAVFLGVGTYQS 244

Query: 122 FEIGITGDRVAGIFTA------------GEAQTLMDIYGIMPGREILIVGSGDVGLIMAR 169
              G+  +   G++ A            G  +T  + +  M G+ ++++G GD  +   R
Sbjct: 245 MRGGLENEDADGVYAALPFLIANTKQLMGFGETRDEPFVSMEGKRVVVLGGGDTAMDCVR 304

Query: 170 RFALEGAR-----VKAVIELMPYPGGLARNVMILNDFNIPLYLSHKV--VEIRGKGRVQR 222
               +GA+      +   E MP   G  R V    +  +    + +   +E+ G G+V  
Sbjct: 305 TSVRQGAKHVTCAYRRDEENMP---GSRREVKNAREEGVEFKFNVQPLGIEVNGNGKVSG 361

Query: 223 VKIVKVD---------ENLREIPGTEFWVDVDTVIISAGLIP-NVKLLTKVGVAIDPSTG 272
           VK+V+ +              + G+E  V  D VI++ G  P N++ L K  V +D  + 
Sbjct: 362 VKMVRTEMGEPDAKGRRRAEIVAGSEHIVPADAVIMAFGFRPHNMEWLAKHSVELD--SQ 419

Query: 273 GPIV-----NDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFID 319
           G I+     ++  +T+ P IF  G+ +  +DLV   + +G  AA+G   +++
Sbjct: 420 GRIIAPEGSDNAFQTSNPKIFAGGDIVRGSDLVVTAIAEGRKAADGIMNWLE 471


>dbj|BAA21091.1| (D86223) glutamate synthase [Pyrococcus sp.]
           Length = 481
           
 Score = 73.4 bits (177), Expect = 5e-12
 Identities = 91/339 (26%), Positives = 145/339 (41%), Gaps = 50/339 (14%)

Query: 4   VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           VA+IG GPAG+ AA +  +LG  V + +     GG+L       +GI  F+      E  
Sbjct: 159 VAIIGAGPAGLTAAGELAKLGYDVTIYEALHEPGGVLM------YGIPEFR---LPKEIV 209

Query: 64  YKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHA 121
            K + +LR   V++ T   V   +   ++           ++E  A  I   AG      
Sbjct: 210 NKEIEKLRKLGVKILTDHVVGRTVTIEEL-----------LQEYDAVFIGSGAGTPRL-- 256

Query: 122 FEIGITGDRVAGIFTAGEAQT---LMDIY-------GIMPGREILIVGSGDVGLIMARRF 171
             I   G  + GI+TA E  T   LM  Y        +  G++++++G+G+  +  AR  
Sbjct: 257 --INAPGINLNGIYTANEFLTRVNLMKAYLFPEYDTPVYVGKKVIVIGAGNTAMDAARSA 314

Query: 172 ALEGARVKAVIELMPYP-GGLARNVMILNDFNIPLYLSHKVVEIRG--KGRVQRVKIVK- 227
              GA V                 V    +  I        VE  G   GRV+ VK  K 
Sbjct: 315 RRFGAEVTIAYRRGEEDVSAREEEVEHAKEEGIKFVYFVNPVEFIGDENGRVKAVKFEKM 374

Query: 228 --VDE----NLREIPGTEFWV--DVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDR 279
             +DE      R+I GT  +V  + DTVII+ G  PN  ++   G+ ++   G  +V++ 
Sbjct: 375 KALDERDARGKRKIVGTGEYVTLEADTVIIAIGKHPNRLIINTPGLKVE--RGKIVVDEN 432

Query: 280 LETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318
           L T++PG+F  G+A+     V   +  G  AA+   E++
Sbjct: 433 LMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHEYL 471


>gi|11497870 NADH oxidase (noxA-1) [Archaeoglobus fulgidus]
           >gi|7447165|pir||F69281 NADH oxidase (noxA-1) homolog -
           Archaeoglobus fulgidus >gi|2650383|gb|AAB90976.1|
           (AE001088) NADH oxidase (noxA-1) [Archaeoglobus
           fulgidus]
           Length = 439
           
 Score = 73.4 bits (177), Expect = 5e-12
 Identities = 85/307 (27%), Positives = 134/307 (42%), Gaps = 53/307 (17%)

Query: 4   VAVIGGGPAGMAAA--IKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFK------- 54
           VA+IGGG AGM+AA  +KA      V + +++ ++        H   GI +F        
Sbjct: 3   VAIIGGGAAGMSAASRVKALRPNWDVKVFEKSRWVS-------HAPCGIPFFVGGAVEKF 55

Query: 55  EELTGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAA 114
           +EL   +  Y    R R ++V T+ARVVEI      E RL V             +++A 
Sbjct: 56  DELCAYDIDY--FKRERGIDVHTNARVVEI-----EEGRLTVDEGGKEASYEWDKLLFAT 108

Query: 115 GARERHAFEIGITGDRVAGIFTAGEAQTLMDI-YGIMPGREILIVGSGDVGLIMARRFAL 173
           G++   A  + + G+ + G+    + +    +    M    +++VGSG +G+ MA     
Sbjct: 109 GSK---AVRLNVEGENLEGVIYVDDIENAERVKIEAMKVDNVVVVGSGYIGVEMADAITR 165

Query: 174 EGARVKAVIELM-----PYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKV 228
            G  V  VIE+M      Y   +A  +    +  + L LS KV    GK RV+     KV
Sbjct: 166 LGKNV-TVIEVMERPLPEYDAEIAAIIKSEMEKYVNLRLSEKVTAFEGKDRVE-----KV 219

Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKL---LTKVGVAIDPSTGGPIVNDRLETTVP 285
             N  E P        +  II+ G+ PN  L     ++GV      G    N R+ET+  
Sbjct: 220 VTNKGEYP-------CELAIIAVGVAPNTDLAKGFVELGV-----KGAIRTNSRMETSRE 267

Query: 286 GIFVAGN 292
            ++ AG+
Sbjct: 268 NVYAAGD 274


>dbj|BAB05342.1| (AP001512) unknown conserved protein [Bacillus halodurans]
           Length = 322
           
 Score = 73.4 bits (177), Expect = 5e-12
 Identities = 78/325 (24%), Positives = 138/325 (42%), Gaps = 35/325 (10%)

Query: 4   VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           V ++GGGP G+AAAI  +  GL  ++I++++ +  I     H  F     K E+    F 
Sbjct: 6   VIIVGGGPCGLAAAIALQNEGLKPLVIEKDNIVSAIHRYPTHQTFFSTSEKLEIGQVPFL 65

Query: 64  --------------YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKT 109
                         Y+ + + + + V    RV+++    D      V++         K 
Sbjct: 66  TEERKPKRSQALVYYREVVKRKQIRVNPFERVIKVTKQED--GTFYVVTSK--RTYHCKQ 121

Query: 110 IIYAAGARERHAFEIGITGDRVAGIF-TAGEAQTLMDIYGIMPGREILIVGSGDVGLIMA 168
           ++ A G  + H   +G+ G+ +  +F    EA    D       ++++++G  +  +  A
Sbjct: 122 VVIATGYYD-HPNSLGVPGEDLPHVFHYFKEAHPYFD-------QDVVVIGGKNSAVDAA 173

Query: 169 RRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKV 228
                 GARV  +     Y   +     IL +F     ++H  V++  + +V+R+   +V
Sbjct: 174 LELEKAGARVTVLYRGDTYSDSV--KPWILPEF--VSLVNHDKVKMVFRAQVKRITASEV 229

Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVN-DRLETTVPGI 287
           +    E  G       D V    G  P+   L  +GVAID  TG PI + + +ET V GI
Sbjct: 230 E---YETQGERKAARADFVFAMIGYHPDHNFLKTMGVAIDHDTGRPIHDPETMETNVEGI 286

Query: 288 FVAGNALVINDLVDYVVEQGELAAE 312
           F+AG     N+  +  +E G    E
Sbjct: 287 FIAGVIAAGNNANEIFIENGRFHGE 311


>pir||A49911 NADH oxidase (hydrogen peroxide-forming) (EC 1.6.-.-) -
           Amphibacillus xylanus >gi|216220|dbj|BAA33809.1|
           (AB018435) NADH oxidase [Amphibacillus xylanus]
           Length = 509
           
 Score = 73.0 bits (176), Expect = 6e-12
 Identities = 80/299 (26%), Positives = 138/299 (45%), Gaps = 36/299 (12%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYF--KEELTG 59
           +DV VIGGGPAG ++AI A   G+ V +I   D  GG +   +    GI  F   +   G
Sbjct: 209 FDVLVIGGGPAGASSAIYAARKGIRVGII--ADRFGGQVMDTL----GIENFIGTKYTEG 262

Query: 60  PEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKR-LKVISPSGIEEIRAKTIIYAAGARE 118
           P+   ++   + +  +     V++ +   +IEK+ L  +       +++KTII A GAR 
Sbjct: 263 PKLISEIEQHVNEYNI----DVMKGLRAHNIEKKDLFEVQLDNGAVLKSKTIILATGARW 318

Query: 119 RHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARV 178
           R   +IG+ G++       G A        +  G+ + +VG G+ G+      AL+ A +
Sbjct: 319 R---DIGVPGEK--EYKNKGVAYCTHCDAPLFEGKHVAVVGGGNSGI----ESALDLAGI 369

Query: 179 KAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENLRE 234
              + +  +   L  + ++        N+ + L+ +  EI G   V+ +  +    N   
Sbjct: 370 VKHVTVFEFMSELKADAVLQERLRSLPNVDVILNAQTTEITGDETVKGISYIDRTTN--- 426

Query: 235 IPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRL-ETTVPGIFVAGN 292
               E  V++    I  GL PN + L   G  ++ +  G IV D+  +T+VPGIF AG+
Sbjct: 427 ---EEKHVELQGAFIQIGLAPNTEWL---GDTVERNQIGEIVIDKKGQTSVPGIFAAGD 479


>sp|O82864|AHPF_PSEPU ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F >gi|3298356|dbj|BAA31469.1|
           (AB010689) AhpF [Pseudomonas putida]
           Length = 520
           
 Score = 73.0 bits (176), Expect = 6e-12
 Identities = 76/301 (25%), Positives = 136/301 (44%), Gaps = 28/301 (9%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           +DV V+GGGPAG AAAI A   G+   +  E  + G +L       F      +E  GP+
Sbjct: 212 FDVLVVGGGPAGAAAAIYAARKGIRTGVAAER-FGGQVLDTLAIENF---ISVQETEGPK 267

Query: 62  FAYKLMNRLR--DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARER 119
            A  L   ++  DV++    R   +I  +  E  L  +  +G   ++AKT+I A GAR R
Sbjct: 268 LATALEEHVKQYDVDIMNLQRGEALIPAA--EGGLHEVRLAGGASLKAKTVILATGARWR 325

Query: 120 HAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARVK 179
                G    R  G+              +  G+ + ++G G+ G+      A++ A + 
Sbjct: 326 EMNVPGEQEYRGRGVAYCPHCDG-----PLFKGKRVAVIGGGNSGV----EAAIDLAGIV 376

Query: 180 AVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREI 235
           A + L+ +   L  + ++        N+ +  S    E+ G G  ++V  ++  +   + 
Sbjct: 377 AQVTLIEFDSQLRADAVLQRKLRSLPNVNVITSALTTEVLGNG--EKVTGLRYKDRSTD- 433

Query: 236 PGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALV 295
              +  V ++ + +  GL+PN   L K  V + P  G  IV+ + +T++PG+F AG+   
Sbjct: 434 --EQHEVALEGIFVQIGLLPNTDWL-KGTVELSP-RGEIIVDAKGQTSIPGVFAAGDVTT 489

Query: 296 I 296
           +
Sbjct: 490 V 490


>pir||H75052 NADH oxidase (noxa-1) PAB0936 - Pyrococcus abyssi (strain Orsay)
           >gi|5458830|emb|CAB50317.1| (AJ248287) NADH oxidase
           (noxA-1) [Pyrococcus abyssi]
           Length = 446
           
 Score = 73.0 bits (176), Expect = 6e-12
 Identities = 77/306 (25%), Positives = 137/306 (44%), Gaps = 48/306 (15%)

Query: 4   VAVIGGGPAGMAAAIKARELG--LSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           V +IGGG AGM+AA + + L     V + +  +++        H   GI Y  E ++  E
Sbjct: 10  VVIIGGGAAGMSAASRVKRLKPEWDVKVFEATEWVS-------HAPCGIPYVVEGISPTE 62

Query: 62  FAYKLMN-------RLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAA 114
              KLM+       + R +++  +A V+E+         ++V    G +      +++A 
Sbjct: 63  ---KLMHYPPEVFIKKRGIDLHLNAEVIEVDT-----GYVRVREKDGEKSYEWDYLVFAN 114

Query: 115 GARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGR---EILIVGSGDVGLIMARRF 171
           GA  +      I G  + G+FTA      + I   M      +++IVG G +GL MA  F
Sbjct: 115 GASPQVP---AIEGVDLKGVFTADLPPDAVAIREYMEKNRVEDVVIVGGGYIGLEMAEAF 171

Query: 172 ALEGARVKAVIE-----LMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIV 226
             +G RV  ++         +   +   +      ++ L L   V+ I GK RV++V + 
Sbjct: 172 VAQGKRVTMIVRGERILRRSFDKEVTDIIEEKLKQHVNLRLQEIVLRIEGKDRVEKV-VT 230

Query: 227 KVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPG 286
              E              D VI++ G+ PN++L  ++GV I   TG    N++++T+V  
Sbjct: 231 DAGE-----------YRADLVILATGIKPNIELARQLGVRIG-ETGAIWTNEKMQTSVEN 278

Query: 287 IFVAGN 292
           ++ AG+
Sbjct: 279 VYAAGD 284


>pir||G64491 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Methanococcus
           jannaschii >gi|1592167|gb|AAB99556.1| (U67594)
           thioredoxin reductase (trxB) [Methanococcus jannaschii]
           Length = 301
           
 Score = 72.2 bits (174), Expect = 1e-11
 Identities = 73/298 (24%), Positives = 131/298 (43%), Gaps = 33/298 (11%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCI---HPGFGIHYFKEEL 57
           ++D  +IG GP G+ A I A    L+ + I++ +  G I    I   +PGF      EE+
Sbjct: 2   IHDTIIIGAGPGGLTAGIYAMRGKLNALCIEKENAGGRIAEAGIVENYPGF------EEI 55

Query: 58  TGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117
            G E A K  N     + +      E+I     E+  KVI+ +   E   KTI+ A G +
Sbjct: 56  RGYELAEKFKNHAE--KFKLPIIYDEVIKIETKERPFKVITKN--SEYLTKTIVIATGTK 111

Query: 118 ERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177
            +   ++G+  D+  G        T+ D +  +  +E++++G     ++ A    L+   
Sbjct: 112 PK---KLGLNEDKFIG--RGISYCTMCDAFFYL-NKEVIVIGRDTPAIMSA--INLKDIA 163

Query: 178 VKAVIELMPYPGGLARNVM---ILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLRE 234
            K ++         A ++M   +    N+ +  + K +EI G+ R + VKI         
Sbjct: 164 KKVIVITDKSELKAAESIMLDKLKEANNVEIIYNAKPLEIVGEERAEGVKI--------S 215

Query: 235 IPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292
           + G E  +  D + IS G +PN + L   G+ +D   G    ++   T + GI+  G+
Sbjct: 216 VNGKEEIIKADGIFISLGHVPNTEFLKDSGIELD-KKGFIKTDENCRTNIDGIYAVGD 272


>gi|4557525 dihydrolipoamide dehydrogenase precursor; E3 component of pyruvate
           dehydrogenase [Homo sapiens]
           >gi|118674|sp|P09622|DLDH_HUMAN DIHYDROLIPOAMIDE
           DEHYDROGENASE, MITOCHONDRIAL PRECURSOR
           >gi|66123|pir||DEHULP dihydrolipoamide dehydrogenase (EC
           1.8.1.4) precursor - human >gi|307137|gb|AAA59527.1|
           (J03490) lipoamide dehydrogenase precursor old gene name
           'LAD' [Homo sapiens]
           Length = 509
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 89/355 (25%), Positives = 158/355 (44%), Gaps = 65/355 (18%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF--------GIHYFK 54
           DV VIG GP G  AAIKA +LG   + I++N+ LGG    C++ G           HY+ 
Sbjct: 43  DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG---TCLNVGCIPSKALLNNSHYY- 98

Query: 55  EELTGPEFAYK-------LMNRLRDVEVRTSA---------------RVVEIINYSDIEK 92
               G +FA +        +N  + +E +++A               +VV +  Y  I  
Sbjct: 99  HMAHGTDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITG 158

Query: 93  RLKVI---SPSGIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
           + +V    +  G + I  K I+ A G+ E   F  GIT D    + + G A +L  +   
Sbjct: 159 KNQVTATKADGGTQVIDTKNILIATGS-EVTPFP-GITIDEDTIVSSTG-ALSLKKV--- 212

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSH 209
               +++++G+G +G+ +   +   GA V AV E + + GG+  ++ I  +F        
Sbjct: 213 --PEKMVVIGAGVIGVELGSVWQRLGADVTAV-EFLGHVGGVGIDMEISKNF-------Q 262

Query: 210 KVVEIRGKGRVQRVKIV--------KVDENLREIPGTEFWV-DVDTVIISAGLIPNVKL- 259
           ++++ +G       K+         K+D ++    G +  V   D +++  G  P  K  
Sbjct: 263 RILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNL 322

Query: 260 -LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEG 313
            L ++G+ +DP    P VN R +T +P I+  G+ +    L     ++G +  EG
Sbjct: 323 GLEELGIELDPRGRIP-VNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEG 376


>gb|AAB01381.1| (L13761) dihydrolipoamide dehydrogenase [Homo sapiens]
           Length = 511
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 89/355 (25%), Positives = 158/355 (44%), Gaps = 65/355 (18%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF--------GIHYFK 54
           DV VIG GP G  AAIKA +LG   + I++N+ LGG    C++ G           HY+ 
Sbjct: 43  DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG---TCLNVGCIPSKALLNNSHYY- 98

Query: 55  EELTGPEFAYK-------LMNRLRDVEVRTSA---------------RVVEIINYSDIEK 92
               G +FA +        +N  + +E +++A               +VV +  Y  I  
Sbjct: 99  HMAHGTDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITG 158

Query: 93  RLKVI---SPSGIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
           + +V    +  G + I  K I+ A G+ E   F  GIT D    + + G A +L  +   
Sbjct: 159 KNQVTATKADGGTQVIDTKNILIATGS-EVTPFP-GITIDEDTIVSSTG-ALSLKKV--- 212

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSH 209
               +++++G+G +G+ +   +   GA V AV E + + GG+  ++ I  +F        
Sbjct: 213 --PEKMVVIGAGVIGVELGSVWQRLGADVTAV-EFLGHVGGVGIDMEISKNF-------Q 262

Query: 210 KVVEIRGKGRVQRVKIV--------KVDENLREIPGTEFWV-DVDTVIISAGLIPNVKL- 259
           ++++ +G       K+         K+D ++    G +  V   D +++  G  P  K  
Sbjct: 263 RILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNL 322

Query: 260 -LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEG 313
            L ++G+ +DP    P VN R +T +P I+  G+ +    L     ++G +  EG
Sbjct: 323 GLEELGIELDPRGRIP-VNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEG 376


>emb|CAB57297.1| (AJ243598) NADH oxidase [Sulfolobus solfataricus]
           Length = 332
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 87/304 (28%), Positives = 136/304 (44%), Gaps = 39/304 (12%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           YD+ VIGGGP G+     A    +  +LID  D LGG L   ++P   I Y    L G +
Sbjct: 4   YDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVS-LYPE-KIVYDVGGLAGIQ 61

Query: 62  FAYKLMNRL--------RDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYA 113
            AY+L  RL         D++V   A ++E  N +        I  +     + KTI  A
Sbjct: 62  -AYELAQRLIEQAKMFGPDIKVNELADMIEKTNDN------MWIVKTDKATYKTKTIFIA 114

Query: 114 AGARERHAFEIGITGD---RVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARR 170
           AG  +     +G  G+      G++     +   +      G+ +LIVG GD     A  
Sbjct: 115 AGIGKIVPSRLGAKGEIEYENRGVYYTVRRKKDFE------GKRVLIVGGGD----SAVD 164

Query: 171 FALEGARVKAVIELMPYPGGL-ARNVMILNDFNIP-LYLSHKVVEIRGKGRVQRVKIVKV 228
           +AL  A V   + L+     L A    +   F +  +Y+ H++ E++G G      I+  
Sbjct: 165 WALTLAPVAKSVTLIHRRDQLRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAII-F 223

Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288
           D   +E    E  +DVD+VIIS G   ++  + K GV +       +VN R+ET +PG++
Sbjct: 224 DNRTKE----EKVLDVDSVIISIGYKGDLGNIPKWGVTM--KGRDIVVNGRMETNLPGVY 277

Query: 289 VAGN 292
             G+
Sbjct: 278 AGGD 281


>gb|AAF21029.1|AF208523_2 (AF208523) HcnB [Pseudomonas aeruginosa]
           Length = 464
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 77/316 (24%), Positives = 132/316 (41%), Gaps = 43/316 (13%)

Query: 6   VIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQ-CIHPGFGIHYFKEELTGPEFAY 64
           ++GGG AGMAAAI+    G+  +L DE    GG++ +  +  G    Y     T      
Sbjct: 7   IVGGGSAGMAAAIELARRGVPCVLFDEASRPGGVVYRGPLRAGVDPAYLGARYT------ 60

Query: 65  KLMNRLR--------DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGA 116
           +++ +LR         +++R ++RVV      D ++ + +     + E+    ++ A G 
Sbjct: 61  RMLEKLRRDFSACAGHIDLRLNSRVVG----GDGQRLMVLDEAERLHEVEYSHLLLATGC 116

Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176
            ER    +   G  + G+   G  Q  +    + P  + LI GSG +  ++A +    G 
Sbjct: 117 HER---SVRFPGWTLPGVMLLGGLQLQIKSGVVKPLGDTLIAGSGPLLPLVACQLHAAGV 173

Query: 177 RVKAVIELMPYPGGLARNVMILND-----------------FNIPLYLSHKVVEIRGKGR 219
           RV  V E   + G +AR  + L +                   IPL+    VVE  G G 
Sbjct: 174 RVAGVYEACAF-GRMARESLALLNKPQLFLDGLSMLGYLKLNGIPLHYGWGVVEASGDGE 232

Query: 220 VQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPI---V 276
           +  V +   DE  R        V   T+ +  G IP  +L  ++G+    S  G +    
Sbjct: 233 LTEVTVAPYDEEWRPDLENARPVKASTLAVGYGFIPRTQLSQQLGLEHGFSDDGYLRAEC 292

Query: 277 NDRLETTVPGIFVAGN 292
           N   +++ P I +AG+
Sbjct: 293 NVWQQSSQPHIHLAGD 308


>gb|AAF34795.1|AF228639_1 (AF228639) lipoamide dehydrogenase precursor [Arabidopsis thaliana]
           Length = 497
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 91/362 (25%), Positives = 151/362 (41%), Gaps = 59/362 (16%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54
           DV +IGGGP G  AAIKA +LGL    I++   LGG    C++ G           H + 
Sbjct: 35  DVVIIGGGPGGYVAAIKASQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 91

Query: 55  E----------ELTGPEFAYKLMNRLRDVEVRTSARVVEII----NYSDIEKRLKVISPS 100
           E          +++  E     M   +D  V+   R +E +      + ++   K ISP+
Sbjct: 92  EAKHSFANHGIKVSSVEVDLPAMLAQKDNAVKNLTRGIEGLFKKNKVTYVKGYGKFISPN 151

Query: 101 ---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMP 151
                    G   ++ K II A G+  +     GIT D    + + G A +L ++     
Sbjct: 152 EVSVETIDGGNTIVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLSEV----- 203

Query: 152 GREILIVGSGDVGLIMARRFALEGARVKAVI---ELMPYPGGLARNVM--ILNDFNIPLY 206
            ++++++G+G +GL M   +   G+ V  V    +++P   G  R      L    +   
Sbjct: 204 PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAGDIVPSMDGEIRKQFQRSLEKQKMKFM 263

Query: 207 LSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTKVG 264
           L  KVV +       ++ +   +       G +  ++ D V++SAG  P      L K+G
Sbjct: 264 LKTKVVSVDSSSDGVKLTVEPAE------GGEQSILEADVVLVSAGRTPFTSGLDLEKIG 317

Query: 265 VAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDND 321
           V  D   G  +VNDR  + VPG++  G+ +    L     E G    E   G    +D D
Sbjct: 318 VETD-KAGRILVNDRFLSNVPGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDYD 376

Query: 322 GI 323
            +
Sbjct: 377 KV 378


>gb|AAF79529.1|AC023673_17 (AC023673) F21D18.28 [Arabidopsis thaliana]
           Length = 505
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 91/362 (25%), Positives = 151/362 (41%), Gaps = 59/362 (16%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54
           DV +IGGGP G  AAIKA +LGL    I++   LGG    C++ G           H + 
Sbjct: 43  DVVIIGGGPGGYVAAIKASQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 99

Query: 55  E----------ELTGPEFAYKLMNRLRDVEVRTSARVVEII----NYSDIEKRLKVISPS 100
           E          +++  E     M   +D  V+   R +E +      + ++   K ISP+
Sbjct: 100 EAKHSFANHGIKVSSVEVDLPAMLAQKDNAVKNLTRGIEGLFKKNKVTYVKGYGKFISPN 159

Query: 101 ---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMP 151
                    G   ++ K II A G+  +     GIT D    + + G A +L ++     
Sbjct: 160 EVSVETIDGGNTIVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLSEV----- 211

Query: 152 GREILIVGSGDVGLIMARRFALEGARVKAVI---ELMPYPGGLARNVM--ILNDFNIPLY 206
            ++++++G+G +GL M   +   G+ V  V    +++P   G  R      L    +   
Sbjct: 212 PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAGDIVPSMDGEIRKQFQRSLEKQKMKFM 271

Query: 207 LSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTKVG 264
           L  KVV +       ++ +   +       G +  ++ D V++SAG  P      L K+G
Sbjct: 272 LKTKVVSVDSSSDGVKLTVEPAE------GGEQSILEADVVLVSAGRTPFTSGLDLEKIG 325

Query: 265 VAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDND 321
           V  D   G  +VNDR  + VPG++  G+ +    L     E G    E   G    +D D
Sbjct: 326 VETD-KAGRILVNDRFLSNVPGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDYD 384

Query: 322 GI 323
            +
Sbjct: 385 KV 386


>pir||G83370 hydrogen cyanide synthase HcnB PA2194 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9948216|gb|AAG05582.1|AE004646_3 (AE004646) hydrogen
           cyanide synthase HcnB [Pseudomonas aeruginosa]
           Length = 464
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 77/316 (24%), Positives = 132/316 (41%), Gaps = 43/316 (13%)

Query: 6   VIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQ-CIHPGFGIHYFKEELTGPEFAY 64
           ++GGG AGMAAAI+    G+  +L DE    GG++ +  +  G    Y     T      
Sbjct: 7   IVGGGSAGMAAAIELARRGVPCVLFDEASRPGGVVYRGPLRAGVDPAYLGARYT------ 60

Query: 65  KLMNRLR--------DVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGA 116
           +++ +LR         +++R ++RVV      D ++ + +     + E+    ++ A G 
Sbjct: 61  RMLEKLRRDFSACAGHIDLRLNSRVVG----GDGQRLMVLDEAERLHEVEYSHLLLATGC 116

Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176
            ER    +   G  + G+   G  Q  +    + P  + LI GSG +  ++A +    G 
Sbjct: 117 HER---SVPFPGWTLPGVMLLGGLQLQIKSGVVKPLGDTLIAGSGPLLPLVACQLHAAGV 173

Query: 177 RVKAVIELMPYPGGLARNVMILND-----------------FNIPLYLSHKVVEIRGKGR 219
           RV  V E   + G +AR  + L +                   IPL+    VVE  G G 
Sbjct: 174 RVAGVYEACAF-GRMARESLALLNKPQLFLDGLSMLGYLKLNGIPLHYGWGVVEASGDGE 232

Query: 220 VQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPI---V 276
           +  V +   DE  R        V   T+ +  G IP  +L  ++G+    S  G +    
Sbjct: 233 LTEVTVAPYDEEWRPDLENARPVKASTLAVGYGFIPRTQLSQQLGLEHGFSDDGYLRAEC 292

Query: 277 NDRLETTVPGIFVAGN 292
           N   +++ P I +AG+
Sbjct: 293 NVWQQSSQPHIHLAGD 308


>gb|AAG21579.1|AC051631_2 (AC051631) lipoamide dehydrogenase, putative; 44693-46402
           [Arabidopsis thaliana]
           Length = 507
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 91/362 (25%), Positives = 151/362 (41%), Gaps = 59/362 (16%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54
           DV +IGGGP G  AAIKA +LGL    I++   LGG    C++ G           H + 
Sbjct: 45  DVVIIGGGPGGYVAAIKASQLGLKTTCIEKRGALGG---TCLNVGCIPSKALLHSSHMYH 101

Query: 55  E----------ELTGPEFAYKLMNRLRDVEVRTSARVVEII----NYSDIEKRLKVISPS 100
           E          +++  E     M   +D  V+   R +E +      + ++   K ISP+
Sbjct: 102 EAKHSFANHGIKVSSVEVDLPAMLAQKDNAVKNLTRGIEGLFKKNKVTYVKGYGKFISPN 161

Query: 101 ---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMP 151
                    G   ++ K II A G+  +     GIT D    + + G A +L ++     
Sbjct: 162 EVSVETIDGGNTIVKGKHIIVATGSDVKSL--PGITIDEKKIVSSTG-ALSLSEV----- 213

Query: 152 GREILIVGSGDVGLIMARRFALEGARVKAVI---ELMPYPGGLARNVM--ILNDFNIPLY 206
            ++++++G+G +GL M   +   G+ V  V    +++P   G  R      L    +   
Sbjct: 214 PKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAGDIVPSMDGEIRKQFQRSLEKQKMKFM 273

Query: 207 LSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVK--LLTKVG 264
           L  KVV +       ++ +   +       G +  ++ D V++SAG  P      L K+G
Sbjct: 274 LKTKVVSVDSSSDGVKLTVEPAE------GGEQSILEADVVLVSAGRTPFTSGLDLEKIG 327

Query: 265 VAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE---GAKEFIDND 321
           V  D   G  +VNDR  + VPG++  G+ +    L     E G    E   G    +D D
Sbjct: 328 VETD-KAGRILVNDRFLSNVPGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDYD 386

Query: 322 GI 323
            +
Sbjct: 387 KV 388


>sp|P09623|DLDH_PIG DIHYDROLIPOAMIDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR
           >gi|66122|pir||DEPGLP dihydrolipoamide dehydrogenase (EC
           1.8.1.4) precursor - pig >gi|164539|gb|AAA31069.1|
           (J03489) lipoamide dehydrogenase precursor [Sus scrofa]
           Length = 509
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 87/355 (24%), Positives = 158/355 (44%), Gaps = 65/355 (18%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF--------GIHYFK 54
           DV VIG GP G  AAIKA +LG   + I++N+ LGG    C++ G           HY+ 
Sbjct: 43  DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG---TCLNVGCIPSKALLNNSHYY- 98

Query: 55  EELTGPEFAYK-------LMNRLRDVEVRTSA---------------RVVEIINYSDIEK 92
               G +FA +        +N  + +E +++A               +VV +  Y  I  
Sbjct: 99  HMAHGKDFASRGIEMSEVRLNLEKMMEQKSNAVKALTGGIAHLFKQNKVVRVNGYGKITG 158

Query: 93  RLKVI---SPSGIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
           + +V    +    E I  K I+ A G+ E   F  GIT D    + + G A +L  +   
Sbjct: 159 KNQVTATKADGSTEVINTKNILIATGS-EVTPFP-GITIDEDTVVSSTG-ALSLKKV--- 212

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSH 209
               +++++G+G +G+ +   +   GA V AV EL+ + GG+  ++ +  +F        
Sbjct: 213 --PEKMVVIGAGVIGVELGSVWQRLGADVTAV-ELLGHVGGIGIDMEVSKNF-------Q 262

Query: 210 KVVEIRGKGRVQRVKIV--------KVDENLREIPGTEFWV-DVDTVIISAGLIPNVKL- 259
           ++++ +G       K++         +D ++    G +  V   D +++  G  P  +  
Sbjct: 263 RILQKQGFKFKLNTKVIGATKKSDGNIDVSIEAASGGKAEVITCDVLLVCIGRRPFTQNL 322

Query: 260 -LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEG 313
            L ++G+ +DP    P VN R +T +P I+  G+ +    L     ++G +  EG
Sbjct: 323 GLEELGIELDPRGRIP-VNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEG 376


>gb|AAA35764.1| (J03620) dihydrolipoamide dehydrogenase precursor [Homo sapiens]
           Length = 509
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 89/355 (25%), Positives = 158/355 (44%), Gaps = 65/355 (18%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF--------GIHYFK 54
           DV VIG GP G  AAIKA +LG   + I++N+ LGG    C++ G           HY+ 
Sbjct: 43  DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG---TCLNVGCIPSKALLNNSHYY- 98

Query: 55  EELTGPEFAYK-------LMNRLRDVEVRTSA---------------RVVEIINYSDIEK 92
               G +FA +        +N  + +E +++A               +VV +  Y  I  
Sbjct: 99  HMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYRKITG 158

Query: 93  RLKVI---SPSGIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
           + +V    +  G + I  K I+ A G+ E   F  GIT D    + + G A +L  +   
Sbjct: 159 KNQVTATKADGGTQVIDTKNILIATGS-EVTPFP-GITIDEDTIVSSTG-ALSLKKV--- 212

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSH 209
               +++++G+G +G+ +   +   GA V AV E + + GG+  ++ I  +F        
Sbjct: 213 --PEKMVVIGAGVIGVELGSVWQRLGADVTAV-EFLGHVGGVGIDMEISKNF-------Q 262

Query: 210 KVVEIRGKGRVQRVKIV--------KVDENLREIPGTEFWV-DVDTVIISAGLIPNVKL- 259
           ++++ +G       K+         K+D ++    G +  V   D +++  G  P  K  
Sbjct: 263 RILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNL 322

Query: 260 -LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEG 313
            L ++G+ +DP    P VN R +T +P I+  G+ +    L     ++G +  EG
Sbjct: 323 GLEELGIELDPRGRIP-VNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEG 376


>pir||E69194 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621795|gb|AAB85213.1| (AE000850) thioredoxin
           reductase [Methanobacterium thermoautotrophicum]
           Length = 303
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 79/298 (26%), Positives = 133/298 (44%), Gaps = 35/298 (11%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDY--LGGILPQC-IHPGFGIHYFKEELT 58
           YD+ VIG GPAG+ A I     G SV+++D+     LG  +P    +PGF      E + 
Sbjct: 5   YDMIVIGAGPAGLTAGIYGGRQGSSVLMLDKGPAGGLGLEVPMMENYPGF------EMIA 58

Query: 59  GPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARE 118
           G     K+  +   V     A + E+    +IEK       +  +   A  II+A G++ 
Sbjct: 59  GMSLVTKMKKQATAV-----AELREMEEVKEIEKGDVFTVKTSRDTYTASAIIFATGSKH 113

Query: 119 RHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGARV 178
           R   ++G+ G+    +   G          +  GR++L+VG G+     A + A+    +
Sbjct: 114 R---QLGVPGEN--DLLGRGVCYCATCDGPLYKGRKVLMVGGGN----SAAQEAVFLKNI 164

Query: 179 KAVIELMPYPGGLARNVMI---LNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREI 235
              + ++     L  +  +   L +  IP+  +  V EI G  RV+ V I         +
Sbjct: 165 GCDVSIVHRRDELRADKYLQDKLREMEIPVIWNSVVKEIGGDERVEEVII------HNRV 218

Query: 236 PGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLE-TTVPGIFVAGN 292
            G +  + VD V I+ G  P  +L   +GV +D   GG I+ D+ + T VP ++ AG+
Sbjct: 219 TGRDETLKVDGVFIAIGEEPLNQLAVDLGVEVD--KGGYIITDKFQRTNVPLVYAAGD 274


>pir||H71171 probable NADH oxidase - Pyrococcus horikoshii
           >gi|3256978|dbj|BAA29661.1| (AP000002) 445aa long
           hypothetical NADH oxidase [Pyrococcus horikoshii]
           Length = 445
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 73/303 (24%), Positives = 140/303 (46%), Gaps = 42/303 (13%)

Query: 4   VAVIGGGPAGMAAAIKARELG--LSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           V +IGGG AGM+AA + + L     V + +  +++        H   GI Y  E L+ P+
Sbjct: 9   VVIIGGGAAGMSAASRVKRLKPEWDVKVFEATEWVS-------HAPCGIPYVVEGLSTPD 61

Query: 62  ----FAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117
               +  ++  + R +++  +A V+E+         ++V    G +      +++A GA 
Sbjct: 62  KLMYYPPEVFIKKRGIDLHLNAEVIEVDT-----GYVRVRENGGEKSYEWDYLVFANGAS 116

Query: 118 ERHAFEIGITGDRVAGIFTAG---EAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALE 174
            +      I G  + G+FTA    +A  + +         ++I+G G +G+ MA  FA +
Sbjct: 117 PQVP---AIEGVNLKGVFTADLPPDALAIREYMEKYKVENVVIIGGGYIGIEMAEAFAAQ 173

Query: 175 GARVKAVI--ELMPYPGGLARNVMILND---FNIPLYLSHKVVEIRGKGRVQRVKIVKVD 229
           G  V  ++  E +           IL +    ++ L L    ++I G+ RV++V +    
Sbjct: 174 GKNVTMIVRGERVLRRSFDKEVTDILEEKLKKHVNLRLQEITMKIEGEERVEKV-VTDAG 232

Query: 230 ENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFV 289
           E   E+           VI++ G+ PN++L  ++GV I   TG    N++++T+V  ++ 
Sbjct: 233 EYKAEL-----------VILATGIKPNIELAKQLGVRIG-ETGAIWTNEKMQTSVENVYA 280

Query: 290 AGN 292
           AG+
Sbjct: 281 AGD 283


>sp|P50970|DLDH_ZYMMO DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONENT OF PYRUVATE AND
           2-OXOGLUTARATE DEHYDROGENASES COMPLEXES)
           >gi|1747421|emb|CAA57734.1| (X82291) dihydrolipoamide
           dehydrogenase [Zymomonas mobilis]
           >gi|2995393|emb|CAA63810.1| (X93605) dihydrolipoamide
           dehydrogenase [Zymomonas mobilis]
           Length = 466
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 93/355 (26%), Positives = 161/355 (45%), Gaps = 72/355 (20%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG-------------- 47
           +D+ V+GGGP G  AAI+A +L L V L+ E  +LGGI   C++ G              
Sbjct: 5   FDLIVLGGGPGGYVAAIRAAQLNLKVALV-ERVHLGGI---CLNWGCIPTKSLLRSAEVY 60

Query: 48  --------FGIHYFKEELTGPEFAY-KLMNRLRDVEVRTSARVVEIINYSDIE------- 91
                   +G+  FK     P+F   K++ R R+V  R ++ V  ++  + +E       
Sbjct: 61  HEMQNAEAYGLTSFK-----PDFDLDKIIARSREVAARLASGVKTLLRKNKVEVISGVGQ 115

Query: 92  ----KRLKVISPSGIEEI-RAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDI 146
               ++++V +  G E+I  AK II A GAR R    +   G  +     A +       
Sbjct: 116 LTGNQQMRVETTEGEEKILEAKDIIIATGARARQLPNVHSDGKHIWTYHHALKPPA---- 171

Query: 147 YGIMPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLY 206
              MP +++L++GSG +G+  A  +A  GA V +++E  P        ++ + D  +  Y
Sbjct: 172 ---MP-KKLLVIGSGAIGIEFASLYADFGAEV-SIVEHAP-------QILPMEDAEVSAY 219

Query: 207 LSHKVVEIRGKGRVQRVKIVKV---DENL-REIPGTEFWVDVDT---VIISAGLIPNVKL 259
           ++ K  + RG   + +  +  +   DE +  EI G +  V  +     I++ G++ NV+ 
Sbjct: 220 VA-KAFKKRGIRILTQSALQNLTPDDEGVTAEIAGADGKVTKERFSHAIVAIGVVANVEN 278

Query: 260 --LTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE 312
             L K+G+ +D   G   V+    T V  ++  G+      L      QG +AAE
Sbjct: 279 IGLDKLGIKLD--RGFIAVDGFGRTNVDHVWAIGDVAGAPCLAHKASHQGVIAAE 331


>gi|11498007 NADH oxidase (noxA-2) [Archaeoglobus fulgidus]
           >gi|7447164|pir||C69299 NADH oxidase (noxA-2) homolog -
           Archaeoglobus fulgidus >gi|2650234|gb|AAB90838.1|
           (AE001077) NADH oxidase (noxA-2) [Archaeoglobus
           fulgidus]
           Length = 436
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 75/296 (25%), Positives = 134/296 (44%), Gaps = 31/296 (10%)

Query: 4   VAVIGGGPAGMAAA--IKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           V VIGGG AGM+AA  +KA +    V + +E +++        H   GI Y  E L+ P 
Sbjct: 3   VVVIGGGAAGMSAASRVKALQPEWEVTVFEETNFVS-------HAPCGIPYVVEGLSDPS 55

Query: 62  ----FAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGAR 117
               +  +     R +++  +A+VVE       +  ++VI     +      ++ A GA 
Sbjct: 56  HLMYYPPEFFREKRGIDLHINAKVVEA-----GDGFVRVIEDGQEKTYEWDKLVIATGAL 110

Query: 118 ERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177
            +     G+  + V  +    +A  L +   +     ++IVG+G VG+ MA   A  G +
Sbjct: 111 PKTPPFEGLELENVFTVRHPVQAAELRE--AVEKAENVVIVGAGYVGVEMAEAAAARGKK 168

Query: 178 VKAVIELMPYP-GGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIP 236
           V  V+E +  P   L R+V  L        + HK+ E       ++V+  + D  +R++ 
Sbjct: 169 V-TVVEFLDQPLPNLDRDVADL--------VKHKLEEKVNLRLGEKVEAFEGDGAVRKVV 219

Query: 237 GTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGN 292
             +     D VI++ G+  N  +  ++G  I   TG    + R++T+V  +F AG+
Sbjct: 220 TDKGEYPADVVIVATGVKANTAIAEQIGCKIG-ETGAIWTDSRMQTSVENVFAAGD 274


>emb|CAA11546.1| (AJ223781) thioredoxin reductase [Staphylococcus aureus]
           Length = 311
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 86/334 (25%), Positives = 142/334 (41%), Gaps = 48/334 (14%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIH----PGFGIHYFKEEL 57
           +D+A+IG GPAGM AA+ A    L  ++I E    GG +         PGF      E +
Sbjct: 6   FDIAIIGAGPAGMTAAVYASRANLKTVMI-ERGIPGGQMANTEEVENFPGF------EMI 58

Query: 58  TGPEFAYKLMNRLRDVEVRTSARVVEIINYSDIEK-----RLKVISPSGIEEIRAKTIIY 112
           TGP+ + K+    +        +   +  Y DI+        KVI+  G +E+ AK +I 
Sbjct: 59  TGPDLSTKMFEHAK--------KFGAVYQYGDIKSVEDKGEYKVIN-FGNKELTAKAVII 109

Query: 113 AAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGL---IMAR 169
           A GA  +   +IG+ G++  G    G +   +        + + ++G GD  +       
Sbjct: 110 ATGAGYK---KIGVPGEQELG--GRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLT 164

Query: 170 RFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGK-GRVQRVKIVKV 228
           +FA +   V    EL      + ++    ND  I    SH +  I  K G+V  V +   
Sbjct: 165 KFADKVTIVHRRDELRAQ--RILQDRAFKND-KIDFIWSHTLKSINEKDGKVGSVTLTST 221

Query: 229 DENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288
            +      G+E   + D V I  G+ P       +G+  D   G  +  D + T+VPGIF
Sbjct: 222 KD------GSEETHEADGVFIYIGMKPLTAPFKDLGITND--VGYIVTKDDMTTSVPGIF 273

Query: 289 VAGNA--LVINDLVDYVVEQGELAAEGAKEFIDN 320
            AG+     +  +V      G +AA+    +I++
Sbjct: 274 AAGDVRDKGLRQIVT-ATGDGSIAAQSTSGYIEH 306


>pir||D72382 hypothetical protein TM0395 - Thermotoga maritima (strain MSB8)
           >gi|4980899|gb|AAD35480.1|AE001719_6 (AE001719) NADH
           oxidase, putative [Thermotoga maritima]
           Length = 425
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 78/313 (24%), Positives = 143/313 (44%), Gaps = 49/313 (15%)

Query: 6   VIGGGPAGMAAAIKARELGLS--VILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           ++G GPAG+ A    RE+     ++LI    Y+G   P   +          ++T  +  
Sbjct: 5   IVGSGPAGLNAIEAIREVDKEGEILLITAEKYVGYSRPLITY------LLGRKVTEEKMY 58

Query: 64  YKLMNRLRD--VEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHA 121
           Y+  + LR+  V+++ + RV ++I      +   V++ SG EEIR   ++ A G +    
Sbjct: 59  YRTEDYLREMRVDIKPATRVEKVI-----PEEKTVVTDSG-EEIRYDKLLIATGGKPFVP 112

Query: 122 FEIGITGDRVAGIFTAGEAQTLMDIY-GIMPGREILIVGSGDVGLIMARRFALEGARVKA 180
              G+TG +    FT  E +  ++ Y      +E +++G G +GL             +A
Sbjct: 113 NIEGLTGKKGVFTFTTWEDEEKVEKYIEENDVKEAVVLGGGLIGL----------KTTEA 162

Query: 181 VIELMPYPGGLARNVMILNDFNIPLYLSHKVVEI-------RGKGRVQRVKIVKV--DEN 231
           ++EL     G+   ++ L D  + +    K  EI        G   +    +VKV  D+ 
Sbjct: 163 LMEL-----GVKVTIVELADRILSVTFDRKASEIITEALKKEGCSVITNDTVVKVNGDDT 217

Query: 232 LREI---PGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIF 288
           +  +    G E  +    ++I+ G+ PNV+ L   G+ I+    G +VN+++ET V G++
Sbjct: 218 VSSVVLKSGKE--IPTKLLVIAIGVKPNVEFLKDSGIEINR---GIVVNEKMETNVEGVY 272

Query: 289 VAGNALVINDLVD 301
            AG+     DL+D
Sbjct: 273 AAGDCTEFYDLID 285


>gb|AAD52148.1|AF129406_2 (AF129406) alkyl hydroperoxide reductase subunit F [Bacteroides
           fragilis]
           Length = 516
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 81/328 (24%), Positives = 143/328 (42%), Gaps = 39/328 (11%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           YDV V GGGPAG AAAI +   GL+V +I E   +GG + + +  G          TG +
Sbjct: 212 YDVIVAGGGPAGSAAAIYSARKGLNVAVIAER--IGGQVKETV--GIENLISVPSTTGSQ 267

Query: 62  FAYKLMNRLRDVEVRTSARVVEIINYSDIEK-----RLKVISPSGIEEIRAKTIIYAAGA 116
            A  L   +       S   ++++ +  IEK     + KV++  G E   A  +I A GA
Sbjct: 268 LADNLKTHM-------SQYPIDLLEHRQIEKIELDGKDKVLTAKGGERFSAPAVIVATGA 320

Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176
             R   ++ + G+  A     G A           G+++ +VG G+ G+      A++ A
Sbjct: 321 SWR---KLNVPGE--AEYIGRGVAFCPHCDGPFYKGKQVAVVGGGNSGI----EAAIDLA 371

Query: 177 RVKAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVKVDENL 232
            + + + ++ +   L  + ++        N+ + +  +  E+ G G   +V  ++V +  
Sbjct: 372 GICSKVTVLEFMDELKADQVLQEKLKSLPNVEVLVHSQTTEVVGNG--DKVTGIRVKDRK 429

Query: 233 REIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVND-RLETTVPGIFVAG 291
            E    E  + +D + +  GL+ N  +   V   ++ +  G IV D    T VPGI+ AG
Sbjct: 430 TE---EERVISLDGIFVQIGLVANSGIFRDV---VEVNRPGEIVIDAHCRTNVPGIYAAG 483

Query: 292 NALVINDLVDYVVEQGELAAEGAKEFID 319
           +   +      ++  GE A      F D
Sbjct: 484 DVSTV-PYKQIIIAMGEGAKAALAAFED 510


>gb|AAK42391.1| Thioredoxin reductase (trxB-1) [Sulfolobus solfataricus]
           Length = 332
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 84/303 (27%), Positives = 133/303 (43%), Gaps = 37/303 (12%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           YD+ VIGGGP G+     A    +  +LID  D LGG L   ++P   I Y    L G +
Sbjct: 4   YDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVS-LYPE-KIVYDVGGLAGIQ 61

Query: 62  FAYKLMNRL--------RDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYA 113
            AY+L  RL         D++V   A ++E  N +        I  +     + KTI  A
Sbjct: 62  -AYELAQRLIEQAKMFGPDIKVNELADMIEKTNDN------MWIVKTDKATYKTKTIFIA 114

Query: 114 AGARERHAFEIGITGD---RVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARR 170
           AG  +     +G  G+      G++     +   +      G+ +LIVG GD  +  A  
Sbjct: 115 AGIGKIVPSRLGAKGEIEYENRGVYYTVRRKKDFE------GKRVLIVGGGDSAVDWALT 168

Query: 171 FALEGARVKAVIELMPYPGGLARNVMILNDFNIP-LYLSHKVVEIRGKGRVQRVKIVKVD 229
            A      K+V  +       A    +   F +  +Y+ H++ E++G G      I+  D
Sbjct: 169 LA---PVAKSVTLIHRRDQFRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAII-FD 224

Query: 230 ENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFV 289
              +E    E  +DVD+VIIS G   ++  + K GV +       +VN R+ET +PG++ 
Sbjct: 225 NRTKE----EKVLDVDSVIISIGYKGDLGNIPKWGVTM--KGRDIVVNGRMETNLPGVYA 278

Query: 290 AGN 292
            G+
Sbjct: 279 GGD 281


>pir||D71200 probable glutamate synthase small chain - Pyrococcus horikoshii
           >gi|3258312|dbj|BAA30995.1| (AP000007) 476aa long
           hypothetical glutamate synthase small chain [Pyrococcus
           horikoshii]
           Length = 476
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 92/343 (26%), Positives = 147/343 (42%), Gaps = 56/343 (16%)

Query: 4   VAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPEFA 63
           VAVIG GPAG+  A +  ++G  V + +     GG+L       +GI         PEF 
Sbjct: 157 VAVIGAGPAGLTCAAELAKMGYDVTIYEALHEPGGVL------AYGI---------PEF- 200

Query: 64  YKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERHAFE 123
            +L   +   E++  + +   I    I  R   I P  ++E  A  I   AG  +     
Sbjct: 201 -RLPKEILRKELKKLSILGVKIKTDHIVGRTVTI-PELLKEYDAIFIGTGAGTPKL---- 254

Query: 124 IGITGDRVAGIFTAGEAQT---LMDIY-------GIMPGREILIVGSGDVGLIMARRFAL 173
           + I G  + GI++A E  T   LM  Y        I+ G+ ++++G+G+  +  AR    
Sbjct: 255 LKIPGINLNGIYSANEFLTRINLMKAYKFPEYDTPIIVGKRVIVIGAGNTAMDAARSALR 314

Query: 174 EGARVKAVIELMPYPGG------LARNVMILNDFNIPLYLSHKVVEIRG--KGRVQRVKI 225
            GA V     ++ Y  G          V    +  +        VE  G   GRV+ VK 
Sbjct: 315 LGAEV-----IIAYRRGEEDMTARIEEVQHAKEEGVKFMFFVNPVEFIGDENGRVKAVKF 369

Query: 226 VKV-------DENLREIPGTEFWVDV--DTVIISAGLIPNVKLLTKVGVAIDPSTGGPI- 275
            K+           R+I GT  +V V  DTV+I+ G  PN +++ K    +     G I 
Sbjct: 370 EKMKPLEERDSRGKRKIIGTGEYVTVETDTVVIAIGQTPN-RIIWKTTPGLKVRENGTIV 428

Query: 276 VNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGAKEFI 318
           V++ L T++PG+F  G+A+     V   +  G  AA+   E++
Sbjct: 429 VDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHEYL 471


>sp|P75531|TRXB_MYCPN THIOREDOXIN REDUCTASE (TRXR) >gi|2146661|pir||S73917 thioredoxin
           reductase (NADPH) (EC 1.6.4.5) - Mycoplasma pneumoniae
           (strain ATCC 29342) >gi|1674293|gb|AAB96239.1|
           (AE000058) thioredoxin reductase [Mycoplasma pneumoniae]
           >gi|2231181|gb|AAC45451.1| (U51988) thioredoxin
           reductase K04_orf315 [Mycoplasma pneumoniae]
           Length = 315
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 71/301 (23%), Positives = 142/301 (46%), Gaps = 36/301 (11%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCI---HPGFGIHYFKEEL 57
           +YDVA++G GPAG+AA I  +   L++ +I+ +   G ++   I   +PG+      + +
Sbjct: 15  IYDVAIVGAGPAGIAAGIYGKRANLNLAIIEGSTPGGKVVKTNIVENYPGY------KSI 68

Query: 58  TGPEFAYKLMNRLRDVE-VRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGA 116
           TGP+   ++ N L D+E     A ++++   +D      ++       + AKT+IYA G 
Sbjct: 69  TGPDLGLEMYNHLIDLEPTFFYANLIKLDKAAD----TFILYLDDKTVVFAKTVIYATGM 124

Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGA 176
            ER   ++G+   +    +  G +   +    +   + + +VG G+     A + AL  A
Sbjct: 125 LER---KLGVA--KEDHFYGKGISYCAICDGSLYKDQVVGVVGGGN----SAIQEALYLA 175

Query: 177 RVKAVIELMPYPGGLARNVMILNDF----NIPLYLSHKVVEIRGKGRVQRVKIVK-VDEN 231
            +   + L+    G   +   LN      N+  +L++ V E+ G   +  + +   +D +
Sbjct: 176 SMAKTVHLIHRREGFRADETALNKLRNLPNVVFHLNYTVKELLGNNTLNGIVLQNTLDHS 235

Query: 232 LREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAG 291
            ++I       D++ V    G     K +  + + +DP  G  I N+++ET++ G+F AG
Sbjct: 236 TKQI-------DLNCVFPYIGFESITKPVEHLNLKLDPQ-GFLITNEQMETSLKGLFAAG 287

Query: 292 N 292
           +
Sbjct: 288 D 288


>pir||D35156 thioredoxin reductase (NADPH) (EC 1.6.4.5) - Eubacterium
           acidaminophilum
           Length = 315
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 82/328 (25%), Positives = 145/328 (44%), Gaps = 30/328 (9%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60
           +YD+A+IG GPAG+AAA+      +  I+I+     G I+    H          E TGP
Sbjct: 4   VYDLAIIGSGPAGLAAALYGARAKMKTIMIEGQKVGGQIV--ITHEVANYPGSVREATGP 61

Query: 61  EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120
               ++  +  +     + +V++ I   D++ ++KVI      E +AK++I A GA  R 
Sbjct: 62  SLIERMEEQANEF---GAEKVMDKIVDVDLDGKIKVIKGEK-AEYKAKSVILATGAAPRL 117

Query: 121 A---FEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177
           A    E  +TG  V+   T  +A    D+       E+ +VG GD  +  A   A    +
Sbjct: 118 AGCPGEQELTGKGVSYCATC-DADFFEDM-------EVFVVGGGDTAVEEAMYLAKFARK 169

Query: 178 VKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPG 237
           V  V          +       +  +    +  + EI+G G V+      V +NL     
Sbjct: 170 VTIVHRRDELRAAKSIQEKAFKNPKLDFMWNSAIEEIKGDGIVESA----VFKNLVTGET 225

Query: 238 TEFWVDVDT----VIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNA 293
           TE++ + +     + +  G IP   +  K  + +D   G  I +D ++T V G+F AG+ 
Sbjct: 226 TEYFANEEDGTFGIFVFIGYIPKSDVF-KGKITLD-DAGYIITDDNMKTNVDGVFAAGDI 283

Query: 294 LV--INDLVDYVVEQGELAAEGAKEFID 319
            V  +  +V    + G +AA  A+++++
Sbjct: 284 RVKSLRQVVTACAD-GAIAATQAEKYVE 310


>gb|AAK42805.1| Mercuric reductase (Hg(II) reductase) (merA) [Sulfolobus
           solfataricus]
           Length = 453
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 87/346 (25%), Positives = 149/346 (42%), Gaps = 61/346 (17%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGF----------GI 50
           M D+ +IG G AG AA I+A ELG+  +++   + +GG    C++ G            +
Sbjct: 1   MEDLVIIGYGAAGFAALIRANELGIKPVVVGYGE-IGG---TCVNVGCVPSKRMLRIGEL 56

Query: 51  HYFKEELTG----PEFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRL---KVISPSGI- 102
           + +  ++ G    PEF     ++   V      +  ++IN  DI+ ++      SP+ + 
Sbjct: 57  YNYSSKVIGKKLFPEFFQAFQDKAEIVNSLRKEKYEDVINSYDIKLKIGKAYFTSPNAVK 116

Query: 103 ---EEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREI---L 156
              E I AK  I A G+         I G    G +T  EA        + P + I    
Sbjct: 117 VNGEIIEAKKFIIATGSSPNIP---NIKGLTEVGFWTNVEA--------LSPDKTISSLA 165

Query: 157 IVGSGDVGLIMARRFALEGARV-------KAVIELMPYPGGLARNVMILNDFNIPLYLSH 209
           I+G   + L  A+ +   G          + + +  P      +N +  ND +IP++ + 
Sbjct: 166 IIGGRALALEFAQMYKRLGVDTTILQRSGRILPDWEPEISLSVKNYLEEND-SIPIFTNV 224

Query: 210 KVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKL-LTKVGVAID 268
           +V E+R KG   ++ +    E           V+ D ++++ G  PNV L L   G+ ++
Sbjct: 225 RVKEVR-KGNGGKIIVTDKGE-----------VEADEILLATGRKPNVDLNLDAAGIELN 272

Query: 269 PSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAEGA 314
              GG  VN+ L T+ P +F AG+ +    L      QG +AAE A
Sbjct: 273 -DKGGIKVNEELRTSNPNVFAAGDVIGGPMLEALAGRQGSIAAENA 317


>gb|AAA19188.1| (U10552) acetoin dehydrogenase [Klebsiella pneumoniae]
           Length = 439
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 87/350 (24%), Positives = 147/350 (41%), Gaps = 63/350 (18%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           YDV +IGGGP G  AAI+A +LGL  +L+ E  +LGGI   C++  +G    K  L G E
Sbjct: 5   YDVLIIGGGPGGYVAAIRAGQLGLRTVLV-EKQHLGGI---CLN--WGCIPTKALLHGAE 58

Query: 62  FAY--------------------KLMNRLRDVEVRTSARVVEIINYSDIE-----KRLKV 96
            A+                    KL+   R V  + +A V  ++  + +       RL+ 
Sbjct: 59  VAHTITHASQLGISVGEVNVDLQKLVQFSRTVSQQLTAGVAYLLKKNGVRVIDGTARLRG 118

Query: 97  ISPSGIE-------EIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
                +E       + RA  +I A GAR R    I   G+ +   F A   + L      
Sbjct: 119 KGQITVEDARGEARDYRADHVILATGARPRALPGIAPDGEHIWTYFEALRPKLL------ 172

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYL-- 207
              + +LI+GSG +G+  A  +   G +V  V         LA  ++ + D  +   +  
Sbjct: 173 --PKSLLIIGSGAIGVEFASLYNDLGCKVTLV--------ELASQILPVEDAEVSAAVRK 222

Query: 208 --SHKVVEIRGKGRVQRVKIVKVDENLR---EIPGTEFWVDVDTVIISAGLIPNVKLLTK 262
               + ++I  +  V +V++   D  +R      G E+  DV+ V+++ G+ PN++ L  
Sbjct: 223 SFEKRGIQIHTQTLVTQVQL--TDTGVRCTLNNTGGEYSQDVERVLLAVGVQPNIEDLGL 280

Query: 263 VGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE 312
             + ++   G    +    T V G++  G+      L      +G L  E
Sbjct: 281 ETLGVELDRGFIKTDAACRTNVFGLYAIGDVAGPPCLAHKASHEGVLCVE 330


>pir||JC4793 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Klebsiella pneumoniae
           >gi|945058|gb|AAB40885.1| (U30887) dihydrolipoamide
           dehydrogenase [Klebsiella pneumoniae]
           Length = 465
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 87/350 (24%), Positives = 147/350 (41%), Gaps = 63/350 (18%)

Query: 2   YDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGPE 61
           YDV +IGGGP G  AAI+A +LGL  +L+ E  +LGGI   C++  +G    K  L G E
Sbjct: 5   YDVLIIGGGPGGYVAAIRAGQLGLRTVLV-EKQHLGGI---CLN--WGCIPTKALLHGAE 58

Query: 62  FAY--------------------KLMNRLRDVEVRTSARVVEIINYSDIE-----KRLKV 96
            A+                    KL+   R V  + +A V  ++  + +       RL+ 
Sbjct: 59  VAHTITHASQLGISVGEVNVDLQKLVQFSRTVSQQLTAGVAYLLKKNGVRVIDGTARLRG 118

Query: 97  ISPSGIE-------EIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
                +E       + RA  +I A GAR R    I   G+ +   F A   + L      
Sbjct: 119 KGQITVEDARGEARDYRADHVILATGARPRALPGIAPDGEHIWTYFEALRPKLL------ 172

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAVIELMPYPGGLARNVMILNDFNIPLYL-- 207
              + +LI+GSG +G+  A  +   G +V  V         LA  ++ + D  +   +  
Sbjct: 173 --PKSLLIIGSGAIGVEFASLYNDLGCKVTLV--------ELASQILPVEDAEVSAAVRK 222

Query: 208 --SHKVVEIRGKGRVQRVKIVKVDENLR---EIPGTEFWVDVDTVIISAGLIPNVKLLTK 262
               + ++I  +  V +V++   D  +R      G E+  DV+ V+++ G+ PN++ L  
Sbjct: 223 SFEKRGIQIHTQTLVTQVQL--TDTGVRCTLNNTGGEYSQDVERVLLAVGVQPNIEDLGL 280

Query: 263 VGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE 312
             + ++   G    +    T V G++  G+      L      +G L  E
Sbjct: 281 ETLGVELDRGFIKTDAACRTNVFGLYAIGDVAGPPCLAHKASHEGVLCVE 330


>sp|P50971|TRXB_EUBAC THIOREDOXIN REDUCTASE (TRXR) >gi|1353197|gb|AAB93303.1| (L04500)
           thioredoxin reductase [Eubacterium acidaminophilum]
           Length = 315
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 82/328 (25%), Positives = 145/328 (44%), Gaps = 30/328 (9%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPGFGIHYFKEELTGP 60
           +YD+A+IG GPAG+AAA+      +  I+I+     G I+    H          E TGP
Sbjct: 4   VYDLAIIGSGPAGLAAALYGARAKMKTIMIEGQKVGGQIV--ITHEVANYPGSVREATGP 61

Query: 61  EFAYKLMNRLRDVEVRTSARVVEIINYSDIEKRLKVISPSGIEEIRAKTIIYAAGARERH 120
               ++  +  +     + +V++ I   D++ ++KVI      E +AK++I A GA  R 
Sbjct: 62  SLIERMEEQANEF---GAEKVMDKIVDVDLDGKIKVIKGEK-AEYKAKSVILATGAAPRL 117

Query: 121 A---FEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMARRFALEGAR 177
           A    E  +TG  V+   T  +A    D+       E+ +VG GD  +  A   A    +
Sbjct: 118 AGCPGEQELTGKGVSYCATC-DADFFEDM-------EVFVVGGGDTAVEEAMYLAKFARK 169

Query: 178 VKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVKIVKVDENLREIPG 237
           V  V          +       +  +    +  + EI+G G V+      V +NL     
Sbjct: 170 VTIVHRRDELRAAKSIQEKAFKNPKLDFMWNSAIEEIKGDGIVESA----VFKNLVTGET 225

Query: 238 TEFWVDVDT----VIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTVPGIFVAGNA 293
           TE++ + +     + +  G IP   +  K  + +D   G  I +D ++T V G+F AG+ 
Sbjct: 226 TEYFANEEDGTFGIFVFIGYIPKSDVF-KGKITLD-DAGYIITDDNMKTNVEGVFAAGDI 283

Query: 294 LV--INDLVDYVVEQGELAAEGAKEFID 319
            V  +  +V    + G +AA  A+++++
Sbjct: 284 RVKSLRQVVTACAD-GAIAATQAEKYVE 310


>sp|O66790|TRXB_AQUAE THIOREDOXIN REDUCTASE (TRXR) >gi|7427756|pir||B70345 thioredoxin
           reductase (NADPH) (EC 1.6.4.5) - Aquifex aeolicus
           >gi|2983154|gb|AAC06756.1| (AE000693) thioredoxin
           reductase [Aquifex aeolicus]
           Length = 323
           
 Score = 69.5 bits (167), Expect = 7e-11
 Identities = 91/343 (26%), Positives = 143/343 (41%), Gaps = 54/343 (15%)

Query: 1   MYDVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGI-LPQCI--HPGFGIHYFKEEL 57
           +YDV +IG GPAG  AAI     G   +++   +  G + + Q I  +PG         +
Sbjct: 12  VYDVIIIGAGPAGTTAAIYTARAGWKTLVLYRAEADGALGVTQKIENYPG---------V 62

Query: 58  TGPEFAYKLMNRLRDVEVRTSARVVE-IINYSDIEKRLKVISPSGIEEIRAKTIIYAAGA 116
            GP   Y+L+  +R+      A  V   +  +D+    K +      E R KTII A+GA
Sbjct: 63  PGPLSGYELLKIMREQAKSFGAEFVRGKVIATDLNSDPKKVYTIDGREFRGKTIIVASGA 122

Query: 117 RERHAFEIGITGDRVAGIFTAGEAQTLMDIYGIMPGREILIVGSGDVGLIMAR---RFA- 172
            ER     G       G+   G              + + ++G  D  +  A    RFA 
Sbjct: 123 MERANKFKGEEEFLGRGVSYCGVCDA-----AFFKDQPVAVIGDDDYAIEEAEFIARFAN 177

Query: 173 -----LEGARVKAVIELMPYPGGLARNVMILNDFNIPLYLSHKVVEIRGKGRVQRVK--- 224
                + G+++KA  E++ +   L          N+ + L H+ +EI G   V+ +K   
Sbjct: 178 KVFFVVPGSKIKAPPEVIEHFEKLP---------NVEILLRHRPIEIVGDQVVKGIKLKD 228

Query: 225 IVKVDENLREIPGTEFWVDVDTVIISAGLIPNVKLLTKVGVAIDPSTGGPIVNDRLETTV 284
           + K +E L E+ G          I   G  P+V  L  +G          +VN+ + T+V
Sbjct: 229 LEKKEEKLLEVNG--------VFIFLGGTKPSVDFL--MGQVEMTEGDCIVVNEEMMTSV 278

Query: 285 PGIFVAGNALVINDLVDYVVEQGELAAEGAKEFIDNDGIRSRK 327
           PG+F AG+ L  N++   VV     AA G K  +  D   S K
Sbjct: 279 PGVFAAGDVL-CNEVKQAVV----AAAMGCKAALAVDKFLSGK 316


>pir||T06332 ferric leghemoglobin reductase isoenzyme 2 precursor - soybean
           >gi|3309269|gb|AAC26053.1| (AF074940) ferric
           leghemoglobin reductase-2 precursor [Glycine max]
           Length = 500
           
 Score = 69.1 bits (166), Expect = 9e-11
 Identities = 91/350 (26%), Positives = 144/350 (41%), Gaps = 60/350 (17%)

Query: 3   DVAVIGGGPAGMAAAIKARELGLSVILIDENDYLGGILPQCIHPG--------FGIHYFK 54
           DV VIGGGP G  AAIKA +LGL    I++   LGG    C++ G           H + 
Sbjct: 38  DVVVIGGGPGGYVAAIKAAQLGLKTTCIEKRGTLGG---TCLNVGCIPSKALLHSSHMYH 94

Query: 55  E----------ELTGPEFAYKLMNRLRDVEVRTSARVVE------IINYSDIEKRLKVIS 98
           E          + +  E     M   +D  V    + +E       +NY  ++   K++S
Sbjct: 95  EAKHAFANHGVKFSSVEVDLPAMMAQKDKAVSNLTKGIEGLFKKNKVNY--VKGYGKLVS 152

Query: 99  PS---------GIEEIRAKTIIYAAGARERHAFEIGITGDRVAGIFTAGEAQTLMDIYGI 149
           PS         G   ++ K II A G+  +     GIT D    + + G A  L +I   
Sbjct: 153 PSEVSVDTTEGGNTVVKGKHIIIATGSDVKSL--PGITIDEKKVVSSTG-ALALTEI--- 206

Query: 150 MPGREILIVGSGDVGLIMARRFALEGARVKAV---IELMPYPGGLARNVM--ILNDFNIP 204
              + ++++G+G +GL M   +   G+ +  V    E++P      R      L    + 
Sbjct: 207 --PKRLIVIGAGYIGLEMGSVWGRLGSEITVVEFASEIVPTMDAEVRKQFQRSLEKQGMK 264

Query: 205 LYLSHKVVEIRGKGRVQRVKIVKVDENLREIPGTEFWVDVDTVIISAGLIP-NVKL-LTK 262
             L  KVV +   G   ++ +           G +  ++ D V++SAG  P   +L L K
Sbjct: 265 FKLKTKVVGVDTSGDGVKLTLEPA------AGGDQTTLEADVVLVSAGRTPFTAELGLDK 318

Query: 263 VGVAIDPSTGGPIVNDRLETTVPGIFVAGNALVINDLVDYVVEQGELAAE 312
           +GV  D   G  +VN+R  T V G++  G+ +    L     E G    E
Sbjct: 319 IGVETD-KIGRILVNERFATNVSGVYAIGDVIPGPMLAHKAEEDGVACVE 367


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.322    0.144    0.412 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 150757199
Number of Sequences: 2977
Number of extensions: 6597085
Number of successful extensions: 19328
Number of sequences better than 1.0e-10: 69
Number of HSP's better than  0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 19141
Number of HSP's gapped (non-prelim): 76
length of query: 407
length of database: 189,106,746
effective HSP length: 55
effective length of query: 352
effective length of database: 156,189,961
effective search space: 54978866272
effective search space used: 54978866272
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 166 (69.1 bits)