BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0189 (imp1) DE:Hypothetical myo-inositol monophosphosphatase (254 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||C75219 probable myo-inositol monophosphosphatase PAB0189 - ... 496 e-140 pir||E71203 hypothetical protein PH1897 - Pyrococcus horikoshii ... 403 e-111 sp|Q57573|Y109_METJA HYPOTHETICAL PROTEIN MJ0109 >gi|2128130|pir... 244 6e-64 pir||D69216 extragenic suppressor protein SuhB homolog - Methano... 140 1e-32 pir||E64414 hypothetical protein MJ0917 - Methanococcus jannaschii 128 7e-29 gb|AAB98922.1| (U67535) conserved hypothetical protein [Methanoc... 128 7e-29 pir||C70470 myo-inositol-1(or 4)-monophosphatase - Aquifex aeoli... 116 2e-25 gb|AAF26973.1|AC018363_18 (AC018363) putative myo-inositol monop... 114 1e-24 gi|11499949 extragenic suppressor (suhB) [Archaeoglobus fulgidus... 108 9e-23 sp|O33832|SUHB_THEMA EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG ... 106 4e-22 pir||E72255 hypothetical protein TM1415 - Thermotoga maritima (s... 106 4e-22 pir||D82285 inositol monophosphate family protein VC0745 [import... 104 1e-21 sp|P22783|SUHB_ECOLI EXTRAGENIC SUPPRESSOR PROTEIN SUHB >gi|7429... 102 5e-21 pir||A35158 suppressor protein suhB - Escherichia coli >gi|14789... 101 1e-20 sp|P54926|MYO1_LYCES MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE 1 (IMP... 99 3e-20 gb|AAK42564.1| Inositol monophosphosphatase, putative (imp3) [Su... 99 5e-20 sp|P54928|MYO3_LYCES MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE 3 (IMP... 99 5e-20 gb|AAF49561.1| (AE003529) CG17029 gene product [Drosophila melan... 98 1e-19 sp|P54927|MYO2_LYCES MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE 2 (IMP... 97 2e-19 pir||C83169 extragenic suppressor protein SuhB PA3818 [imported]... 95 9e-19 sp|O49071|MYOP_MESCR MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE (IMPAS... 92 8e-18 pir||D72564 probable myo-inositol-1(or 4)-monophosphatase APE179... 91 1e-17 pir||E82554 extragenic supressor XF2476 [imported] - Xylella fas... 89 4e-17 sp|P44333|SUHB_HAEIN EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG ... 87 2e-16 gb|AAF51694.1| (AE003594) CG9389 gene product [Drosophila melano... 87 3e-16 pir||F81092 extragenic suppressor protein SuhB NMB1347 [imported... 85 8e-16 pir||B81848 inositol monophosphate family protein NMA1559 [impor... 85 1e-15 dbj|BAB06354.1| (AP001516) myo-inositol-1(or 4)-monophosphatase ... 80 3e-14 sp|O07203|SUHB_MYCTU EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG ... 79 4e-14 pir||G81026 inositol monophosphatase family protein NMB1924 [imp... 79 6e-14 pir||D81971 hypothetical protein NMA0529 [imported] - Neisseria ... 79 6e-14 sp|Q45499|SUHB_BACSU EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG ... 78 1e-13 pir||T08560 hypothetical protein T22F8.20 - Arabidopsis thaliana... 77 2e-13 gi|7657236 inositol(myo)-1(or 4)-monophosphatase 2 [Homo sapiens... 76 3e-13 gb|AAF07824.1|AF200432_1 (AF200432) brain myo-inositol monophosp... 76 3e-13 gb|AAD50453.1|AF170704_3 (AF170704) SpcA [Streptomyces spectabilis] 76 5e-13 sp|P74158|SUHB_SYNY3 EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG ... 75 8e-13 gb|AAF51693.1| (AE003594) CG9391 gene product [Drosophila melano... 73 3e-12 gb|AAD21685.1| (AC004793) Contains similarity to gi|1653332 extr... 73 4e-12 gb|AAF49559.1| (AE003529) CG17027 gene product [Drosophila melan... 72 6e-12 gb|AAF63339.1|AF244574_2 (AF244574) myo-inositol-1-monophosphota... 72 7e-12 sp|P46813|SUHB_MYCLE EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG ... 71 1e-11 gb|AAB94817.1| (AF005905) inositol monophosphate phosphatase [My... 71 1e-11 pir||S24343 myo-inositol-1(or 4)-monophosphatase (EC 3.1.3.25) -... 71 1e-11 sp|P29219|MYOP_XENLA MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE (IMPAS... 71 1e-11 sp|P20456|MYOP_BOVIN MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE (IMPAS... 70 3e-11 sp|O55023|MYOP_MOUSE MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE (IMPAS... 70 3e-11 gb|AAF49562.1| (AE003529) CG17026 gene product [Drosophila melan... 69 6e-11 >pir||C75219 probable myo-inositol monophosphosphatase PAB0189 - Pyrococcus abyssi (strain Orsay) >gi|5457711|emb|CAB49202.1| (AJ248283) hypothetical myo-inositol monophosphosphatase [Pyrococcus abyssi] Length = 254 Score = 496 bits (1264), Expect = e-140 Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 1 MSVKAWRKIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKA 60 MSVKAWRKIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKA Sbjct: 1 MSVKAWRKIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKA 60 Query: 61 LGVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPV 120 LGVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPV Sbjct: 61 LGVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPV 120 Query: 121 VKKLYEGIPGQGAYLNGQRIKVRKLGEKPSISFYTRGKGIELLNHVKRTRTLGAIALELA 180 VKKLYEGIPGQGAYLNGQRIKVRKLGEKPSISFYTRGKGIELLNHVKRTRTLGAIALELA Sbjct: 121 VKKLYEGIPGQGAYLNGQRIKVRKLGEKPSISFYTRGKGIELLNHVKRTRTLGAIALELA 180 Query: 181 YLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVN 240 YLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVN Sbjct: 181 YLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVN 240 Query: 241 DEELLKMVLSLIEK 254 DEELLKMVLSLIEK Sbjct: 241 DEELLKMVLSLIEK 254 >pir||E71203 hypothetical protein PH1897 - Pyrococcus horikoshii >gi|3258337|dbj|BAA31020.1| (AP000007) 254aa long hypothetical protein [Pyrococcus horikoshii] Length = 254 Score = 403 bits (1024), Expect = e-111 Identities = 188/254 (74%), Positives = 234/254 (92%) Query: 1 MSVKAWRKIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKA 60 MSVK WRKIA+DII DFD N+MPLFG+ +A ET+ ISPSGDETKVVDKVAEN+++SKFK Sbjct: 1 MSVKTWRKIAIDIIRDFDHNIMPLFGNPKASETISISPSGDETKVVDKVAENIIISKFKD 60 Query: 61 LGVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPV 120 LGVN+VSEE+G I+QGS+YTV++DPLDGSYNFI+GIPFFA+SVAIF ++P+YAFIYEP+ Sbjct: 61 LGVNVVSEEIGRIDQGSDYTVVVDPLDGSYNFINGIPFFAVSVAIFHEKDPIYAFIYEPI 120 Query: 121 VKKLYEGIPGQGAYLNGQRIKVRKLGEKPSISFYTRGKGIELLNHVKRTRTLGAIALELA 180 V++LYEGIPG+G+YLNG++IKVR+L EKPSISFYT+GKG ++++ VKRTRTLGAIALELA Sbjct: 121 VERLYEGIPGKGSYLNGEKIKVRELAEKPSISFYTKGKGTKIIDKVKRTRTLGAIALELA 180 Query: 181 YLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVN 240 YLARGALD VVDIRNYLRPTDIAAGV+IA+EAGA+VKD +G ++E++FSAT+KVN++A N Sbjct: 181 YLARGALDAVVDIRNYLRPTDIAAGVVIAREAGAIVKDLDGKDVEITFSATEKVNIIAAN 240 Query: 241 DEELLKMVLSLIEK 254 +EELL+ +L IEK Sbjct: 241 NEELLETILRSIEK 254 >sp|Q57573|Y109_METJA HYPOTHETICAL PROTEIN MJ0109 >gi|2128130|pir||E64313 hypothetical protein MJ0109 - Methanococcus jannaschii >gi|11513829|pdb|1DK4|A Chain A, Crystal Structure Of Mj0109 Gene Product Inositol Monophosphatase >gi|11513830|pdb|1DK4|B Chain B, Crystal Structure Of Mj0109 Gene Product Inositol Monophosphatase >gi|1498875|gb|AAB98091.1| (U67468) extragenic suppressor (suhB) [Methanococcus jannaschii] Length = 252 Score = 244 bits (617), Expect = 6e-64 Identities = 116/250 (46%), Positives = 165/250 (65%), Gaps = 3/250 (1%) Query: 6 WRKIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKALGVNI 65 W +I +I + ++ ++P FG VG SPSGDET++ DK++E++ + K+L VNI Sbjct: 3 WDEIGKNIAKEIEKEILPYFGRKDKSYVVGTSPSGDETEIFDKISEDIALKYLKSLNVNI 62 Query: 66 VSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLY 125 VSEE+GVI+ SE+TV+IDP+DGS+NFI+GIPFFA +FK EP Y YE + K Y Sbjct: 63 VSEELGVIDNSSEWTVVIDPIDGSFNFINGIPFFAFCFGVFKNNEPYYGLTYEFLTKSFY 122 Query: 126 EGIPGQGAYLNGQRIKVRKLGEKPSISFYTRGKGIE---LLNHVKRTRTLGAIALELAYL 182 E G+GAYLNG++IKV+ + Y K I+ L N VKR R GA LE+ Y+ Sbjct: 123 EAYKGKGAYLNGRKIKVKDFNPNNIVISYYPSKKIDLEKLRNKVKRVRIFGAFGLEMCYV 182 Query: 183 ARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVNDE 242 A+G LD V D+R +R DIA+ II KEAGAL+ D NGDE++ +ATD++N++ N + Sbjct: 183 AKGTLDAVFDVRPKVRAVDIASSYIICKEAGALITDENGDELKFDLNATDRLNIIVANSK 242 Query: 243 ELLKMVLSLI 252 E+L ++L L+ Sbjct: 243 EMLDIILDLL 252 >pir||D69216 extragenic suppressor protein SuhB homolog - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621964|gb|AAB85369.1| (AE000863) extragenic suppressor protein SuhB homolog [Methanobacterium thermoautotrophicum] Length = 280 Score = 140 bits (350), Expect = 1e-32 Identities = 93/270 (34%), Positives = 144/270 (52%), Gaps = 22/270 (8%) Query: 6 WRKIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKALG--V 63 W+ +A+ + ++ V PL G AGE + + G TK++D VAE+ V ++ G V Sbjct: 9 WKGVAVRMAEQVERAVSPLVGTEDAGEIIKMGADGTPTKLIDLVAEDEAVGVLESTGRPV 68 Query: 64 NIVSEEMGVIEQGSE-----YTVLIDPLDGSYNFISGIPFFALSVAIFK----GEEPVYA 114 I+SEE+GV+ SE ++DPLDG+ N I IPF+ +SVA+ + G P Sbjct: 69 TIISEEIGVLHINSEGDEPGIIFVVDPLDGTSNAIRNIPFYGISVAVAERHPDGAAPTLN 128 Query: 115 FIYEPVVKK-----LYEGIPGQGAYLNGQRIKVRKLGEKPSIS-----FYTRGKGIELLN 164 + VK LY I GQGA+LN + I S + TR + ++ + Sbjct: 129 NVLMGFVKNFATGDLYWAIKGQGAFLNEKAISSSSQSSLDRTSLGAFIYGTRFRRVDSIC 188 Query: 165 HV-KRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDE 223 V +R R LG++ALELAY+A G+ D +D+R LR DIAA +I +EAG +V + G E Sbjct: 189 RVIRRMRILGSVALELAYVASGSYDAFMDLRENLRIVDIAASKLIVEEAGGVVTNERGGE 248 Query: 224 IEVSFSATDKVNLVAVNDEELLKMVLSLIE 253 I+ + + +LVA + EL + ++ +E Sbjct: 249 IDGLLNVKARTSLVAAGNLELHEKIMQTLE 278 >pir||E64414 hypothetical protein MJ0917 - Methanococcus jannaschii Length = 574 Score = 128 bits (318), Expect = 7e-29 Identities = 87/286 (30%), Positives = 150/286 (52%), Gaps = 43/286 (15%) Query: 8 KIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKF-KALGVNIV 66 KIA+ +I++ D+ + PL G +A E V I G TK +D +AEN+ ++ K G ++ Sbjct: 8 KIAMKVIDEIDKKIKPLIGWEKADEVVKIGADGTPTKRIDVIAENMAINILEKFSGGILI 67 Query: 67 SEEMG--VIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAI--FKGEEP----------- 111 SEE+G V+ EY ++DP+DG+YN + IP ++ S+A+ KGE+ Sbjct: 68 SEEIGLKVVGDELEYIFILDPIDGTYNALKSIPIYSTSIAVAKIKGEDKKLIRENINNID 127 Query: 112 -VYAFI---------YEPVVKKL-----YEGIPGQGAYL--NGQRIKVRKLGEKP----S 150 + +FI Y +VK L Y I G+G++L +G++IK+ K S Sbjct: 128 WIKSFIANKYTINDLYVGIVKNLATGDLYYAIKGEGSFLEKDGEKIKIETKNIKDLKEAS 187 Query: 151 ISFYTRGKGIELLNHVK-----RTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAG 205 + + G +LL +K R R G++ALE+ Y+ GALD +++ R DIA Sbjct: 188 VGLFVYGLSNDLLEFLKERKVRRVRLFGSMALEMCYVVSGALDAYINVNENSRLCDIAGA 247 Query: 206 VIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVNDEELLKMVLSL 251 +I +E A+V + NG + + ++ +L+ V+++ L K +++L Sbjct: 248 YVICREGNAIVTNKNGKPLNMKLHLMERTSLI-VSNKYLHKKLIAL 292 >gb|AAB98922.1| (U67535) conserved hypothetical protein [Methanococcus jannaschii] Length = 574 Score = 128 bits (318), Expect = 7e-29 Identities = 87/286 (30%), Positives = 150/286 (52%), Gaps = 43/286 (15%) Query: 8 KIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKF-KALGVNIV 66 KIA+ +I++ D+ + PL G +A E V I G TK +D +AEN+ ++ K G ++ Sbjct: 8 KIAMKVIDEIDKKIKPLIGWEKADEVVKIGADGTPTKRIDVIAENMAINILEKFSGGILI 67 Query: 67 SEEMG--VIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAI--FKGEEP----------- 111 SEE+G V+ EY ++DP+DG+YN + IP ++ S+A+ KGE+ Sbjct: 68 SEEIGLKVVGDELEYIFILDPIDGTYNALKSIPIYSTSIAVAKIKGEDKKLIRENINNID 127 Query: 112 -VYAFI---------YEPVVKKL-----YEGIPGQGAYL--NGQRIKVRKLGEKP----S 150 + +FI Y +VK L Y I G+G++L +G++IK+ K S Sbjct: 128 WIKSFIANKYTINDLYVGIVKNLATGDLYYAIKGEGSFLEKDGEKIKIETKNIKDLKEAS 187 Query: 151 ISFYTRGKGIELLNHVK-----RTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAG 205 + + G +LL +K R R G++ALE+ Y+ GALD +++ R DIA Sbjct: 188 VGLFVYGLSNDLLEFLKERKVRRVRLFGSMALEMCYVVSGALDAYINVNENSRLCDIAGA 247 Query: 206 VIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVNDEELLKMVLSL 251 +I +E A+V + NG + + ++ +L+ V+++ L K +++L Sbjct: 248 YVICREGNAIVTNKNGKPLNMKLHLMERTSLI-VSNKYLHKKLIAL 292 >pir||C70470 myo-inositol-1(or 4)-monophosphatase - Aquifex aeolicus >gi|2984224|gb|AAC07753.1| (AE000766) myo-inositol-1(or 4)-monophosphatase [Aquifex aeolicus] Length = 264 Score = 116 bits (288), Expect = 2e-25 Identities = 75/192 (39%), Positives = 102/192 (53%), Gaps = 21/192 (10%) Query: 41 DETKVVDKVAEN---VVVSKFKALGVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIP 97 D VDK +E V+ KF +V EEMG GSEY IDPLDG+ N+I+G P Sbjct: 41 DFVSYVDKTSEERIKEVILKFFP-DHEVVGEEMGAEGSGSEYRWFIDPLDGTKNYINGFP 99 Query: 98 FFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVR-------------- 143 FA+SV + KGEEP+ +Y P KLY G G GAY+NG+RIKV+ Sbjct: 100 IFAVSVGLVKGEEPIVGAVYLPYFDKLYWGAKGLGAYVNGKRIKVKDNESLKHAGVVYGF 159 Query: 144 KLGEKPSISFYTRGKGIELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIA 203 + IS Y ++ V R GA A++L +A G DG+++ ++P DI Sbjct: 160 PSRSRRDISIYL-NIFKDVFYEVGSMRRPGAAAVDLCMVAEGIFDGMMEFE--MKPWDIT 216 Query: 204 AGVIIAKEAGAL 215 AG++I KEAG + Sbjct: 217 AGLVILKEAGGV 228 >gb|AAF26973.1|AC018363_18 (AC018363) putative myo-inositol monophosphatase [Arabidopsis thaliana] Length = 271 Score = 114 bits (282), Expect = 1e-24 Identities = 71/201 (35%), Positives = 110/201 (54%), Gaps = 21/201 (10%) Query: 47 DKVAENVVVSKFKALGVN--IVSEE----MGVIEQGSEYTVLIDPLDGSYNFISGIPFFA 100 DK E +V + K L N + EE GV E E T ++DPLDG+ NF+ G PF Sbjct: 48 DKGCEELVFNHLKQLFPNHKFIGEETTAAFGVTELTDEPTWIVDPLDGTTNFVHGFPFVC 107 Query: 101 LSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEKPSISFYT----- 155 +S+ + G+ PV +Y P++++L+ G+ G+GA+LNG+RIKV E + T Sbjct: 108 VSIGLTIGKVPVVGVVYNPIMEELFTGVQGKGAFLNGKRIKVSAQSELLTALLVTEAGTK 167 Query: 156 RGKGI---------ELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGV 206 R K LL V+ R G+ AL+L +A G +D ++ + P DIAAG+ Sbjct: 168 RDKATLDDTTNRINSLLTKVRSLRMSGSCALDLCGVACGRVDIFYEL-GFGGPWDIAAGI 226 Query: 207 IIAKEAGALVKDSNGDEIEVS 227 +I KEAG L+ D +G +++++ Sbjct: 227 VIVKEAGGLIFDPSGKDLDIT 247 >gi|11499949 extragenic suppressor (suhB) [Archaeoglobus fulgidus] >gi|7445379|pir||D69546 extragenic suppressor (suhB) homolog - Archaeoglobus fulgidus >gi|2650719|gb|AAB91288.1| (AE001112) extragenic suppressor (suhB) [Archaeoglobus fulgidus] Length = 252 Score = 108 bits (266), Expect = 9e-23 Identities = 78/228 (34%), Positives = 121/228 (52%), Gaps = 16/228 (7%) Query: 34 VGISPSGDETKVVDKVAENVVVSKFKALGVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFI 93 VG+ G TK D+VAE+ + + V +V+EE GV+ +G + V +DPLDG++N Sbjct: 33 VGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVF-VALDPLDGTFNAT 91 Query: 94 SGIPFFALSVAIF---KGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEK-- 148 GIP +++S+ K ++ + ++Y Y GAY NG+RI+V E Sbjct: 92 RGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYA-DSSGAYRNGERIEVSDAEELYC 150 Query: 149 PSISFYTRGKGIELLNHVKRTRTLGAIALELAYLARGALDGVVDIR--NYLRPTDIAAGV 206 +I +Y K KR R G+ A EL + A G+ D +DIR LR D AAGV Sbjct: 151 NAIIYYPDRK-----FPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGV 205 Query: 207 IIAKEAGALVKDSNGDEI-EVSFSATDKVNLVAVNDEELLKMVLSLIE 253 IA++AG V + +G+ + F +++N+VA N E+L +L LI+ Sbjct: 206 FIAEKAGGKVTELDGESLGNKKFDMQERLNIVAAN-EKLHPKLLELIK 252 >sp|O33832|SUHB_THEMA EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG >gi|11278812|pir||T50642 myo-inositol-1(or 4)-monophosphatase homolog [imported] - Thermotoga maritima >gi|2330879|emb|CAA04517.1| (AJ001073) hypothetical protein [Thermotoga maritima] Length = 256 Score = 106 bits (261), Expect = 4e-22 Identities = 74/219 (33%), Positives = 123/219 (55%), Gaps = 17/219 (7%) Query: 46 VDKVAENVVVSKFKAL--GVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSV 103 +D+ A+ ++V + + NI++EE G+ E+G + IDP+DG+ NF+ G+P F++S+ Sbjct: 41 IDREAQRMIVDEIRKFFPDENIMAEE-GIFEKGDRLWI-IDPIDGTINFVHGLPNFSISL 98 Query: 104 AIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRK-------LGEKPSISFYTR 156 A + E ++ P + + G GA+ NG+RI+V + +G S +T Sbjct: 99 AYVENGEVKLGVVHAPALNETLYAEEGSGAFFNGERIRVSENASLEECVGSTGSYVDFT- 157 Query: 157 GKGIELL-NHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGAL 215 GK IE + +R R LG+ AL AY+ G +D V R + P DIAAG+II KEAG + Sbjct: 158 GKFIERMEKRTRRIRILGSAALNAAYVGAGRVDFFVTWR--INPWDIAAGLIIVKEAGGM 215 Query: 216 VKDSNGDEIEVSFSATDKVNLVAVNDEELLKMVLSLIEK 254 V D +G E +FS + ++D E++K+V ++E+ Sbjct: 216 VTDFSGKEAN-AFSKNFIFSNGLIHD-EVVKVVNEVVEE 252 >pir||E72255 hypothetical protein TM1415 - Thermotoga maritima (strain MSB8) >gi|4981980|gb|AAD36486.1|AE001794_2 (AE001794) inositol monophosphatase family protein, putative [Thermotoga maritima] Length = 232 Score = 106 bits (261), Expect = 4e-22 Identities = 74/219 (33%), Positives = 123/219 (55%), Gaps = 17/219 (7%) Query: 46 VDKVAENVVVSKFKAL--GVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSV 103 +D+ A+ ++V + + NI++EE G+ E+G + IDP+DG+ NF+ G+P F++S+ Sbjct: 17 IDREAQRMIVDEIRKFFPDENIMAEE-GIFEKGDRLWI-IDPIDGTINFVHGLPNFSISL 74 Query: 104 AIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRK-------LGEKPSISFYTR 156 A + E ++ P + + G GA+ NG+RI+V + +G S +T Sbjct: 75 AYVENGEVKLGVVHAPALNETLYAEEGSGAFFNGERIRVSENASLEECVGSTGSYVDFT- 133 Query: 157 GKGIELL-NHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGAL 215 GK IE + +R R LG+ AL AY+ G +D V R + P DIAAG+II KEAG + Sbjct: 134 GKFIERMEKRTRRIRILGSAALNAAYVGAGRVDFFVTWR--INPWDIAAGLIIVKEAGGM 191 Query: 216 VKDSNGDEIEVSFSATDKVNLVAVNDEELLKMVLSLIEK 254 V D +G E +FS + ++D E++K+V ++E+ Sbjct: 192 VTDFSGKEAN-AFSKNFIFSNGLIHD-EVVKVVNEVVEE 228 >pir||D82285 inositol monophosphate family protein VC0745 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655190|gb|AAF93910.1| (AE004160) inositol monophosphate family protein [Vibrio cholerae] Length = 288 Score = 104 bits (256), Expect = 1e-21 Identities = 75/200 (37%), Positives = 115/200 (57%), Gaps = 20/200 (10%) Query: 39 SGDETKVVDKVAENVVVSKFKALGVN--IVSEEMGVIE-QGSEYTVLIDPLDGSYNFISG 95 S D VDK AE ++VS K+ I++EE G+IE + E +IDPLDG+ NF+ G Sbjct: 57 SNDFVTNVDKEAEAIIVSTIKSSYPEHCIIAEEGGLIEGKDKEVQWIIDPLDGTTNFVKG 116 Query: 96 IPFFALSVAI-FKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKL----GEKPS 150 P FA+S+A+ F+G+ V A +Y+P+ +L+ G GA LN RI+V+ + G + Sbjct: 117 FPHFAVSIAVRFRGKTEV-ACVYDPMTNELFTAQRGAGAQLNNARIRVQPIKDLQGAVLA 175 Query: 151 ISFYTRGKG-----IELLN----HVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTD 201 +F + K +++L+ R G+ AL+L YLA +DG ++ L+P D Sbjct: 176 TAFPFKQKQHSESFMKILSAMFVECADFRRTGSAALDLCYLAANRVDGYFELG--LKPWD 233 Query: 202 IAAGVIIAKEAGALVKDSNG 221 +AAG +IA+EAGA+V D G Sbjct: 234 MAAGELIAREAGAIVTDFAG 253 >sp|P22783|SUHB_ECOLI EXTRAGENIC SUPPRESSOR PROTEIN SUHB >gi|7429923|pir||D65030 myo-inositol-1(or 4)-monophosphatase (EC 3.1.3.25) [validated] - Escherichia coli >gi|1788882|gb|AAC75586.1| (AE000339) enhances synthesis of sigma32 in mutant; extragenic suppressor, may modulate RNAse III lethal action [Escherichia coli K12] >gi|1799941|dbj|BAA16427.1| (D90883) EXTRAGENIC SUPPRESSOR PROTEIN SUHB. [Escherichia coli] >gi|1799950|dbj|BAA16435.1| (D90884) EXTRAGENIC SUPPRESSOR PROTEIN SUHB. [Escherichia coli] Length = 267 Score = 102 bits (251), Expect = 5e-21 Identities = 76/201 (37%), Positives = 109/201 (53%), Gaps = 22/201 (10%) Query: 39 SGDETKVVDKVAENVVVSKFKALGVN--IVSEEMGVIEQGSEYTV--LIDPLDGSYNFIS 94 S D VDK AE V++ + I++EE G +E G++ V +IDPLDG+ NFI Sbjct: 36 SNDFVTNVDKAAEAVIIDTIRKSYPQHTIITEESGELE-GTDQDVQWVIDPLDGTTNFIK 94 Query: 95 GIPFFALSVAI-FKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIK---VRKL-GEKP 149 +P FA+S+A+ KG V A +Y+P+ +L+ GQGA LNG R++ R L G Sbjct: 95 RLPHFAVSIAVRIKGRTEV-AVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTIL 153 Query: 150 SISFYTRGKGI---------ELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPT 200 + F + K +L N R G+ AL+LAY+A G +DG +I LRP Sbjct: 154 ATGFPFKAKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIG--LRPW 211 Query: 201 DIAAGVIIAKEAGALVKDSNG 221 D AAG ++ +EAG +V D G Sbjct: 212 DFAAGELLVREAGGIVSDFTG 232 >pir||A35158 suppressor protein suhB - Escherichia coli >gi|147899|gb|AAA67506.1| (M34828) extragenic suppressor [Escherichia coli] Length = 267 Score = 101 bits (248), Expect = 1e-20 Identities = 76/201 (37%), Positives = 108/201 (52%), Gaps = 22/201 (10%) Query: 39 SGDETKVVDKVAENVVVSKFKALGVN--IVSEEMGVIEQGSEYTV--LIDPLDGSYNFIS 94 S D VDK AE V++ + I++EE G +E G++ V +IDPLDG+ NFI Sbjct: 36 SNDFVTNVDKAAEAVIIDTIRKSYPQHTIITEESGELE-GTDQDVQWVIDPLDGTTNFIK 94 Query: 95 GIPFFALSVAI-FKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRI---KVRKL-GEKP 149 +P FA+S+A+ KG V A +Y+P+ +L+ GQGA LNG R+ R L G Sbjct: 95 RLPHFAVSIAVRIKGRTEV-AVVYDPMRNELFTATRGQGAQLNGYRLLGSTARDLDGTIL 153 Query: 150 SISFYTRGKGI---------ELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPT 200 + F + K +L N R G+ AL+LAY+A G +DG +I LRP Sbjct: 154 ATGFPFKAKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIG--LRPW 211 Query: 201 DIAAGVIIAKEAGALVKDSNG 221 D AAG ++ +EAG +V D G Sbjct: 212 DFAAGELLVREAGGIVSDFTG 232 >sp|P54926|MYO1_LYCES MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE 1 (IMPASE 1) (IMP 1) (INOSITOL MONOPHOSPHATASE 1) >gi|1098977|gb|AAB19030.1| (U39444) myo-inositol monophosphatase 1 [Lycopersicon esculentum] Length = 273 Score = 99.5 bits (244), Expect = 3e-20 Identities = 62/201 (30%), Positives = 106/201 (51%), Gaps = 21/201 (10%) Query: 47 DKVAENVVVSKFKAL--GVNIVSEEM----GVIEQGSEYTVLIDPLDGSYNFISGIPFFA 100 DK E+++ + K + EE G + E T ++DP+DG+ NF+ G P Sbjct: 48 DKACEDLIFNHLKQHFPSHKFIGEETSAATGDFDLTDEPTWIVDPVDGTTNFVHGFPSVC 107 Query: 101 LSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGE------------- 147 +S+ + G+ P +Y+P++ +L+ GI G+GAYLNG+ IKV E Sbjct: 108 VSIGLTIGKIPTVGVVYDPIIDELFTGINGKGAYLNGKPIKVSSQSELVKSLLGTEVGTT 167 Query: 148 KPSISFYTRGKGI-ELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGV 206 + +++ T + I LL V+ R G+ AL+L ++A G L+ + + Y P D+A G Sbjct: 168 RDNLTVETTTRRINNLLFKVRSLRMCGSCALDLCWVACGRLE-LFYLIGYGGPWDVAGGA 226 Query: 207 IIAKEAGALVKDSNGDEIEVS 227 +I KEAG ++ D +G E +++ Sbjct: 227 VIVKEAGGVLFDPSGSEFDIT 247 >gb|AAK42564.1| Inositol monophosphosphatase, putative (imp3) [Sulfolobus solfataricus] Length = 264 Score = 99.1 bits (243), Expect = 5e-20 Identities = 73/231 (31%), Positives = 116/231 (49%), Gaps = 19/231 (8%) Query: 39 SGDETKVVDKVAENVVVSKFKALGVNI--VSEEMGVIEQGS--EYTVLIDPLDGSYNFIS 94 +GD T+V+DK +E + G+ VSEE GV + +Y LIDPLDGS NF+ Sbjct: 33 AGDTTRVIDKKSEEYIFQLLNDTGLKFKFVSEESGVRVPSNSYDYVALIDPLDGSNNFVL 92 Query: 95 GIPFFALSVAIFKGE-----EPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEKP 149 G+P++++SVAI+ + + F+ + K+Y AYLNG +K +G P Sbjct: 93 GVPWYSISVAIYGKSSNSLLDSLGGFVSHISIDKIY-SYDTSSAYLNGNPLKAEIIGNSP 151 Query: 150 S----ISFYTRG--KGIELLNHVK--RTRTLGAIALELAYLARGALDGVVDIRNYLRPTD 201 S F RG K +++L+ +K + R+ G+ +L++ G DIR LR D Sbjct: 152 SNVVITYFDERGIDKILKVLSALKGYKIRSFGSASLDMILTCMGKAKLYFDIRGKLRNVD 211 Query: 202 IAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVN-DEELLKMVLSL 251 IAA K ++ NG EI K++ + V+ D+ L+K + S+ Sbjct: 212 IAASANFCKRLNSIPSTLNGKEISSGIDDIYKIDEIIVSRDQSLMKNLYSI 262 >sp|P54928|MYO3_LYCES MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE 3 (IMPASE 3) (IMP 3) (INOSITOL MONOPHOSPHATASE 3) >gi|7445377|pir||T07795 myo-inositol-1(or 4)-monophosphatase (EC 3.1.3.25) isoform 3 - tomato >gi|1098971|gb|AAB19031.1| (U39059) myo-inositol monophosphatase 3 [Lycopersicon esculentum] Length = 268 Score = 99.1 bits (243), Expect = 5e-20 Identities = 64/201 (31%), Positives = 99/201 (48%), Gaps = 21/201 (10%) Query: 47 DKVAENVVVSKFKAL--GVNIVSEEM----GVIEQGSEYTVLIDPLDGSYNFISGIPFFA 100 DK E+ + + K + EE G E E T ++DPLDG+ NF+ G PF Sbjct: 48 DKACEDFIFNHLKQRFPSHKFIGEETTAACGNFELTDEPTWIVDPLDGTTNFVHGFPFVC 107 Query: 101 LSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGE------------- 147 +S+ + ++P +Y P++ +L+ GI G+GA+LNG+ IKV E Sbjct: 108 VSIGLTIEKKPTVGVVYNPIIDELFTGIDGKGAFLNGKPIKVSSQSELVKALLATEAGTN 167 Query: 148 -KPSISFYTRGKGIELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGV 206 + T G+ LL V+ R G+ AL L +A G LD ++ + P D+A G Sbjct: 168 RDKLVVDATTGRINSLLFKVRSLRMCGSCALNLCGVACGRLDLFYEL-EFGGPWDVAGGA 226 Query: 207 IIAKEAGALVKDSNGDEIEVS 227 +I KEAG V D +G E +++ Sbjct: 227 VIVKEAGGFVFDPSGSEFDLT 247 >gb|AAF49561.1| (AE003529) CG17029 gene product [Drosophila melanogaster] Length = 284 Score = 97.5 bits (239), Expect = 1e-19 Identities = 81/237 (34%), Positives = 114/237 (47%), Gaps = 32/237 (13%) Query: 41 DETKVVDKVAENVVVSKFKAL---GVNIVSEEMGVIEQGSEYTV----LIDPLDGSYNFI 93 D V DK E+++ A + I EE V ++ +E T +IDP+DG+ NFI Sbjct: 47 DLVTVYDKQIEDILTEGLVAAFPESLIIGEEESAVSQRQAELTDAPTWIIDPIDGTTNFI 106 Query: 94 SGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGE-KPSIS 152 IP +SV + +E V IY P +L+ G GAYLNG+ I K+ K ++ Sbjct: 107 HRIPHCCISVGLAINKELVVGIIYNPPANELFSAYKGHGAYLNGEPIHTSKVTTIKQAVI 166 Query: 153 FY---------TRGKGIELL----NHVKRTRTLGAIALELAYLARGALDG--VVDIRNYL 197 Y R K ++ L ++ TR G+ AL L Y+A G D V D L Sbjct: 167 AYEISLIHAAGVRDKNVKRLYKMASNATGTRCFGSAALTLCYVATGQCDAYHVED----L 222 Query: 198 RPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVNDEELLKMVLSLIEK 254 +P DIAAG II EAG V ++G + +V K + V EL K V+SLIE+ Sbjct: 223 KPWDIAAGAIILTEAGGTVCHTSGSKFDVM-----KPDCVCAATPELAKNVISLIEE 274 >sp|P54927|MYO2_LYCES MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE 2 (IMPASE 2) (IMP 2) (INOSITOL MONOPHOSPHATASE 2) >gi|7445378|pir||T07800 myo-inositol-1(or 4)-monophosphatase (EC 3.1.3.25) isoform 2 [validated] - tomato >gi|1098975|gb|AAB19029.1| (U39443) myo-inositol monophosphatase 2 [Lycopersicon esculentum] Length = 265 Score = 97.1 bits (238), Expect = 2e-19 Identities = 59/183 (32%), Positives = 94/183 (51%), Gaps = 15/183 (8%) Query: 59 KALGVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYE 118 K +G + G E E T ++DPLDG+ NF+ G PF +S+ + ++PV +Y Sbjct: 61 KFIGEETTAAASGNFELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIEKKPVVGVVYN 120 Query: 119 PVVKKLYEGIPGQGAYLNGQRIKVRK--------------LGEKPSISFYTRGKGIELLN 164 P++ +L+ I G+GA+LNG+ I+V +I T G+ ++ Sbjct: 121 PIIDELFTAIYGRGAFLNGKSIRVSSESQLVKALVATEVGTNRDKAIVDATTGRINRVIF 180 Query: 165 HVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEI 224 V+ R G+ AL L +A G LD +I + P D+AAG +I EAG LV D +G E Sbjct: 181 KVRSLRMSGSCALNLCGVACGRLDLFYEI-EFGGPWDVAAGALIVIEAGGLVLDPSGSEF 239 Query: 225 EVS 227 +++ Sbjct: 240 DLT 242 >pir||C83169 extragenic suppressor protein SuhB PA3818 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949992|gb|AAG07205.1|AE004799_11 (AE004799) extragenic suppressor protein SuhB [Pseudomonas aeruginosa] Length = 271 Score = 94.8 bits (232), Expect = 9e-19 Identities = 81/233 (34%), Positives = 123/233 (52%), Gaps = 28/233 (12%) Query: 41 DETKVVDKVAENVVVSKF-KALGVN-IVSEEMGVIE---QGSEYTVLIDPLDGSYNFISG 95 D VD+ AE +V+ KA + I+ EE G IE +G++Y +IDPLDG+ NFI G Sbjct: 38 DYVTEVDRAAEQTIVAALRKAYPTHAIMGEEGGFIEGSGEGADYLWVIDPLDGTTNFIHG 97 Query: 96 IPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKV--RKL--GEKPSI 151 +P FA+S+A +A + +PV ++ + G+GA LNG+R++V RK G Sbjct: 98 VPHFAVSIACKYKGRLEHAVVLDPVRQEEFTASRGRGAALNGRRLRVSGRKSLEGALLGT 157 Query: 152 SFYTRGKGIELL-NHVKRTRTL----------GAIALELAYLARGALDGVVDIRNYLRPT 200 F R I+ L N++ R+L GA +L+LAY+A G D + L Sbjct: 158 GFPFRDNQIDNLDNYLNMFRSLVGQTAGIRRAGAASLDLAYVAAGRYDAFWEFG--LSEW 215 Query: 201 DIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVNDEELLKMVLSLIE 253 D+AAG ++ +EAG LV D G S +K ++VA N + K +L+ I+ Sbjct: 216 DMAAGALLVQEAGGLVSDFTG-----SHEFLEKGHIVAGN-TKCFKALLTTIQ 262 >sp|O49071|MYOP_MESCR MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE (IMPASE) (IMP) (INOSITOL MONOPHOSPHATASE) >gi|7445376|pir||T12205 myo-inositol-1(or 4)-monophosphatase (EC 3.1.3.25) - common ice plant >gi|2708322|gb|AAB92418.1| (AF037220) inositol monophosphatase [Mesembryanthemum crystallinum] Length = 270 Score = 91.7 bits (224), Expect = 8e-18 Identities = 61/201 (30%), Positives = 99/201 (48%), Gaps = 21/201 (10%) Query: 47 DKVAENVVVSKFKALGVN--IVSEEM----GVIEQGSEYTVLIDPLDGSYNFISGIPFFA 100 DK E+++ + K N + EE G E E T ++DPLDG+ NF+ G PF Sbjct: 48 DKSCEDIIFNCLKQQYPNHKFIGEETTAAYGATELTDEPTWIVDPLDGTTNFVHGFPFVC 107 Query: 101 LSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEKPSISFYT----- 155 +S+ + G+ P +Y P++ +L+ G+ QGA+LNG I V E + T Sbjct: 108 VSIGLTIGKVPTVGVVYNPIMNELFTGVRRQGAFLNGVPIHVSSKDELVNCLLVTEVGTK 167 Query: 156 RGKGI---------ELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGV 206 R K LL V+ R G+ AL+L +A G D + + Y D+ AG+ Sbjct: 168 RDKSTVDATTNRINGLLFKVRSIRMAGSCALDLCGIACGRADLMYE-NGYGGAWDVTAGI 226 Query: 207 IIAKEAGALVKDSNGDEIEVS 227 +I +EAG ++ D +G + +++ Sbjct: 227 VIVEEAGGVIFDPSGKDFDIT 247 >pir||D72564 probable myo-inositol-1(or 4)-monophosphatase APE1798 - Aeropyrum pernix (strain K1) >gi|5105488|dbj|BAA80801.1| (AP000062) 268aa long hypothetical myo-inositol-1(or 4)-monophosphatase [Aeropyrum pernix] Length = 268 Score = 91.3 bits (223), Expect = 1e-17 Identities = 84/250 (33%), Positives = 123/250 (48%), Gaps = 35/250 (14%) Query: 24 LFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKA-LG-VNIVSEEMG-VIEQGSEYT 80 L D E +G SG ET V DK AE+ ++ + LG V ++SEE G V + S+ Sbjct: 22 LLRDLACSEDLGRVVSG-ETTVADKRAEDYILDLLRRELGQVQVISEEAGGVASKTSDAP 80 Query: 81 V-LIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIP-----GQGAY 134 + L+DPLDGS N++S I + ++SVA +P I V +Y G+P G+G Y Sbjct: 81 IALVDPLDGSTNYLSCITWCSVSVAF---ADPRSGEILAGSVAPVYAGMPVSFARGKGCY 137 Query: 135 LNGQRIKVRKLGEKPSI-----SFYTRGKG--------IELLNHVKR---TRTLGAIALE 178 G ++ E PSI S Y G I L V+R R+LG+ ALE Sbjct: 138 HGGLKV------EDPSIRGSIISVYVDEPGAIESVAGAIGRLKGVRRDFKVRSLGSAALE 191 Query: 179 LAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVA 238 LAY A G + D+R LR D+AA V +E G +V D++G + + ++V V Sbjct: 192 LAYTAIGYIAVFADLRARLRNIDVAAAVGAVRECGGVVTDAHGQPLRIGVWRVERVGSVV 251 Query: 239 VNDEELLKMV 248 + +E L + Sbjct: 252 ASLDEALARI 261 >pir||E82554 extragenic supressor XF2476 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9107673|gb|AAF85274.1|AE004055_12 (AE004055) extragenic supressor [Xylella fastidiosa] Length = 275 Score = 89.3 bits (218), Expect = 4e-17 Identities = 68/217 (31%), Positives = 109/217 (49%), Gaps = 21/217 (9%) Query: 41 DETKVVDKVAENVVVSKFKAL--GVNIVSEEMGVIEQGSEYTV-LIDPLDGSYNFISGIP 97 D VD++AE V+V + K I+ EE G+ QG+ + +IDPLDG+ N++ G P Sbjct: 39 DYASDVDEMAEKVIVKELKRAYPEYGILGEEGGL--QGNHRIMWVIDPLDGTSNYLRGFP 96 Query: 98 FFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKL----GEKPSISF 153 + +S+A+ + EP A I++P+ +L+ G GA LN ++I+V G + F Sbjct: 97 HYCISIALVENGEPTDAVIFDPLRNELFTASRGAGAILNERKIRVANRKDLNGTMLNTGF 156 Query: 154 YTRGKG---------IELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAA 204 R + LL + R G+ AL+LAY+A G D + ++ D+AA Sbjct: 157 SPRERSRAHAQLKCVDALLMQAEDIRRSGSAALDLAYVACGRADAYFEAG--IKVWDVAA 214 Query: 205 GVIIAKEAGALVKDSNG-DEIEVSFSATDKVNLVAVN 240 G+++ +EAG V D G D + + LVA N Sbjct: 215 GMLLVREAGGYVCDFKGADAPRMDDKGPESCQLVAGN 251 >sp|P44333|SUHB_HAEIN EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG >gi|1074073|pir||F64103 suppressor protein suhB - Haemophilus influenzae (strain Rd KW20) >gi|1573958|gb|AAC22595.1| (U32775) extragenic suppressor (suhB) [Haemophilus influenzae Rd] Length = 267 Score = 87.4 bits (213), Expect = 2e-16 Identities = 67/234 (28%), Positives = 115/234 (48%), Gaps = 27/234 (11%) Query: 1 MSVKAWRKIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKA 60 ++++A RK I ++++ DA GI+ D VDK +E ++ + Sbjct: 7 IAIRAARKAGNVIAKNYERR------DAIESTQKGIN---DYVTNVDKASEAEIIEVIRK 57 Query: 61 LGVN--IVSEEMGVIE-QGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIY 117 + I++EE G IE + S+ +IDPLDG+ NF++G+P F++S+A+ +Y Sbjct: 58 SYPDHTIITEETGAIEGKDSDVQWIIDPLDGTRNFMTGLPHFSVSIAVRVKNRTEVGVVY 117 Query: 118 EPVVKKLYEGIPGQGAYLNGQRIKVRKLGE-------------KPSISFYTRGKGIELLN 164 +P+ +L+ + G+GA LN R++V E +P + L+ Sbjct: 118 DPIRNELFTAVRGEGAKLNEVRLRVDSKREIQGSILATGFPFKQPKLMPAQFAMMNALIE 177 Query: 165 HVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKD 218 R G+ AL+L Y+A +DG ++ L+ D AAG +I +EAG LV D Sbjct: 178 DAADFRRTGSAALDLCYVASNRIDGYFEMG--LKAWDCAAGDLIVREAGGLVCD 229 >gb|AAF51694.1| (AE003594) CG9389 gene product [Drosophila melanogaster] Length = 596 Score = 86.6 bits (211), Expect = 3e-16 Identities = 56/177 (31%), Positives = 90/177 (50%), Gaps = 18/177 (10%) Query: 65 IVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKL 124 I E G++ + T +IDP+DG+ NF+ P++ +SVA +E + IY P +K + Sbjct: 344 ISKSETGMVTLTDDPTWIIDPIDGTMNFVHHFPYYCISVAYLVNQETQFGIIYNPPMKNM 403 Query: 125 YEGIPGQGAYLNGQRIKV---RKLGEKPSISFYTRGKGIELLNH---------VKRT--- 169 Y G+GA +NG+ I+ L + Y+ G E N VK+T Sbjct: 404 YTAQLGKGAQMNGEMIRTTGQTNLSAAMVLQEYSSGSN-EARNQVATENSQRLVKKTHAM 462 Query: 170 RTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEV 226 R++G+ A+ LA +A G D + L D+AAG +I EAG +V D G+E+++ Sbjct: 463 RSIGSSAMCLAMVASGVADAFYNFG--LHVWDMAAGALIVTEAGGVVMDPAGEELDI 517 >pir||F81092 extragenic suppressor protein SuhB NMB1347 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226591|gb|AAF41721.1| (AE002483) extragenic suppressor protein SuhB [Neisseria meningitidis MC58] Length = 261 Score = 85.0 bits (207), Expect = 8e-16 Identities = 69/219 (31%), Positives = 111/219 (50%), Gaps = 23/219 (10%) Query: 46 VDKVAENVVVSKFKALGVN--IVSEEMGVI-EQGSEYTVLIDPLDGSYNFISGIPFFALS 102 VD+ +E ++V K + I EE G + +EY +IDPLDG+ NF+ G P +A+S Sbjct: 43 VDRNSEIILVEALKEAYPHHKITCEESGSHGKAAAEYEWIIDPLDGTTNFLHGHPQYAIS 102 Query: 103 VAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEK---------PSISF 153 +A+ A +Y P +Y G+GA LN +RI+V E P + Sbjct: 103 MALLHKGVLQEALVYAPERNDVYMASRGKGALLNDRRIRVSNRIELNRCLIGTGFPVVDQ 162 Query: 154 YTRGKGIELL-NHVKRT---RTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIA 209 K + +L + + +T R GA +L+L +A G DG + L+P DIAAG +I Sbjct: 163 SMMDKYLAILKDFLAKTAGGRREGAASLDLCAVATGRFDGFFEFN--LKPWDIAAGALIV 220 Query: 210 KEAGALVKDSNGDEIEVSFSATDKVNLVAVNDEELLKMV 248 +EAG +V D +G++ + ++VA N + L +M+ Sbjct: 221 QEAGGIVTDMSGED-----GWLESGDIVAANPKVLAQML 254 >pir||B81848 inositol monophosphate family protein NMA1559 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7380200|emb|CAB84786.1| (AL162756) inositol monophosphate family protein [Neisseria meningitidis Z2491] Length = 261 Score = 84.7 bits (206), Expect = 1e-15 Identities = 69/219 (31%), Positives = 111/219 (50%), Gaps = 23/219 (10%) Query: 46 VDKVAENVVVSKFKALGVN--IVSEEMGVI-EQGSEYTVLIDPLDGSYNFISGIPFFALS 102 VD+ +E ++V K + I EE G + +EY +IDPLDG+ NF+ G P +A+S Sbjct: 43 VDRNSEIILVEALKEAYPHHKITCEESGSHGKAAAEYEWIIDPLDGTTNFLHGHPQYAIS 102 Query: 103 VAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEK---------PSISF 153 +A+ A +Y P +Y G+GA LN +RI+V E P + Sbjct: 103 MALLHKGVLQEALVYAPERNDVYMASRGKGALLNDRRIRVSNRIELNRCLIGTGFPVVDQ 162 Query: 154 YTRGKGIELL-NHVKRT---RTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIA 209 K + +L + + +T R GA +L+L +A G DG + L+P DIAAG +I Sbjct: 163 SMMDKYLVILKDFLAKTAGGRREGAASLDLCAVATGRFDGFFEFN--LKPWDIAAGALIV 220 Query: 210 KEAGALVKDSNGDEIEVSFSATDKVNLVAVNDEELLKMV 248 +EAG +V D +G++ + ++VA N + L +M+ Sbjct: 221 QEAGGIVTDMSGED-----GWLESGDIVAANPKVLAQML 254 >dbj|BAB06354.1| (AP001516) myo-inositol-1(or 4)-monophosphatase [Bacillus halodurans] Length = 267 Score = 79.6 bits (193), Expect = 3e-14 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 20/160 (12%) Query: 82 LIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIK 141 +IDP+DG+ NF+ FA+SV +F IY+ + +++ + G+GAY+ ++K Sbjct: 88 IIDPIDGTMNFVHSQYHFAISVGVFHDGVGKVGIIYDVMNDEMFYAVQGEGAYVRDTKLK 147 Query: 142 ---------------VRKLGEKPSISFYTRGKGIELLNHVKRTRTLGAIALELAYLARGA 186 R L E+ + RG+ L+ V+ R+ G+ ALELAY+A G Sbjct: 148 TITTSSVNESVVGVNARWLVEQRA---PFRGELERLVRDVRGVRSFGSAALELAYVAAGR 204 Query: 187 LDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEV 226 LDG V ++ L P D AAG ++ E G + G+E+ + Sbjct: 205 LDGYVSLK--LSPWDYAAGKVLLAEVGGTITTLQGEELSL 242 >sp|O07203|SUHB_MYCTU EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG >gi|7429927|pir||H70530 probable extragenic suppressor protein SuhB - Mycobacterium tuberculosis (strain H37RV) >gi|2181992|emb|CAB09491.1| (Z96072) suhB [Mycobacterium tuberculosis] Length = 290 Score = 79.2 bits (192), Expect = 4e-14 Identities = 68/220 (30%), Positives = 101/220 (45%), Gaps = 29/220 (13%) Query: 24 LFGDARAGETVGI----SPSGDETKVVDKVAENVVVSKFKAL--GVNIVSEEMG-----V 72 +FG +RAG+ G S D VVD E ++ + L G I+ EE G Sbjct: 33 VFGISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPILGEEGGGPADVT 92 Query: 73 IEQGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQG 132 T ++DP+DG+ NF+ GIP +A+S+ G V + + + +Y G G Sbjct: 93 ATPSDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLG 152 Query: 133 AYLNGQR------------IKVRKLGEKPSISFYTRGKGIELLNH----VKRTRTLGAIA 176 A+L +R + + LG S R K ELL H V+ R +G+ A Sbjct: 153 AHLTDERGRHVLRCTGVDELSMALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAA 212 Query: 177 LELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALV 216 L+L +A G LD + + ++ D AAG +IA EAGA V Sbjct: 213 LDLCMVAAGRLDAYYE--HGVQVWDCAAGALIAAEAGARV 250 >pir||G81026 inositol monophosphatase family protein NMB1924 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7227181|gb|AAF42253.1| (AE002541) inositol monophosphatase family protein [Neisseria meningitidis MC58] Length = 231 Score = 78.8 bits (191), Expect = 6e-14 Identities = 56/176 (31%), Positives = 86/176 (48%), Gaps = 20/176 (11%) Query: 65 IVSEEMGVIEQ--------GSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFI 116 ++ EEM EQ G + ++DP+DG+ NF++G+P FA+SVA + I Sbjct: 25 MLGEEMSRQEQSALWEQYSGEKGLWIVDPIDGTNNFVNGLPHFAVSVAFVRNGRAELGVI 84 Query: 117 YEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEK-------PSISFYTRGK---GIELLNHV 166 Y PV + + GQGA+LNG R+ +R + +K I + GK + L Sbjct: 85 YNPVSGECFYAERGQGAFLNGTRLPLRLVDKKLNEAIAGVEIKYLRSGKLSSRMSTLAPF 144 Query: 167 KRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGD 222 R++G+ L+ YLA G D V + + D AAG +I +EAG + GD Sbjct: 145 GTIRSMGSSTLDWCYLACGRYD--VYVHGGQKLWDYAAGALIFEEAGGRLTTLEGD 198 >pir||D81971 hypothetical protein NMA0529 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379271|emb|CAB83821.1| (AL162753) hypothetical protein NMA0529 [Neisseria meningitidis Z2491] Length = 264 Score = 78.8 bits (191), Expect = 6e-14 Identities = 56/176 (31%), Positives = 86/176 (48%), Gaps = 20/176 (11%) Query: 65 IVSEEMGVIEQ--------GSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFI 116 ++ EEM EQ G + ++DP+DG+ NF++G+P FA+SVA + I Sbjct: 58 MLGEEMSRQEQSALWEQYSGEKGLWIVDPIDGTNNFVNGLPHFAVSVAFVRNGRAELGVI 117 Query: 117 YEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEK-------PSISFYTRGK---GIELLNHV 166 Y PV + + GQGA+LNG R+ +R + +K I + GK + L Sbjct: 118 YNPVSGECFYAERGQGAFLNGTRLPLRLVDKKLNEAIAGVEIKYLRSGKLSSRMSTLAPF 177 Query: 167 KRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGD 222 R++G+ L+ YLA G D V + + D AAG +I +EAG + GD Sbjct: 178 GTIRSMGSSTLDWCYLACGRYD--VYVHGGQKLWDYAAGALIFEEAGGRLTTLEGD 231 >sp|Q45499|SUHB_BACSU EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG >gi|7429926|pir||E69864 myo-inositol-1(or 4)-monophosphatase homolog yktC - Bacillus subtilis >gi|2633838|emb|CAB13340.1| (Z99111) similar to myo-inositol-1(or 4)-monophosphatase [Bacillus subtilis] >gi|3282150|gb|AAC24940.1| (AF012285) unknown [Bacillus subtilis] Length = 265 Score = 77.6 bits (188), Expect = 1e-13 Identities = 58/193 (30%), Positives = 94/193 (48%), Gaps = 18/193 (9%) Query: 46 VDKVAENVVVSKFKAL--GVNIVSEE-MGVIEQGSEYTV-LIDPLDGSYNFISGIPFFAL 101 +DK E + + + G I+ EE G E V +IDP+DG+ NF+ FA+ Sbjct: 45 IDKETEKFFIDRIQETFPGHRILGEEGQGDKIHSLEGVVWIIDPIDGTMNFVHQQRNFAI 104 Query: 102 SVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIK------VRKLGEKPSISFYT 155 S+ IF+ E IY+ V +LY G+GAY+N ++ + + + ++ T Sbjct: 105 SIGIFENGEGKIGLIYDVVHDELYHAFSGRGAYMNETKLAPLKETVIEEAILAINATWVT 164 Query: 156 RGKGIE------LLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIA 209 + I+ L+ V+ TR+ G+ ALELA +A G +D + +R L P D AAG ++ Sbjct: 165 ENRRIDQSVLAPLVKRVRGTRSYGSAALELANVAAGRIDAYITMR--LAPWDYAAGCVLL 222 Query: 210 KEAGALVKDSNGD 222 E G G+ Sbjct: 223 NEVGGTYTTIEGE 235 >pir||T08560 hypothetical protein T22F8.20 - Arabidopsis thaliana >gi|4914424|emb|CAB43627.1| (AL050351) Inositol monophosphatase-like protein [Arabidopsis thaliana] >gi|7270895|emb|CAB80575.1| (AL161594) Inositol monophosphatase-like protein [Arabidopsis thaliana] Length = 286 Score = 76.9 bits (186), Expect = 2e-13 Identities = 63/225 (28%), Positives = 106/225 (47%), Gaps = 18/225 (8%) Query: 45 VVDKVAENVVVSK-FKALGVN-IVSEEMG--VIEQGSEYTVLIDPLDGSYNFISGIPFFA 100 + D++AE +VS F+ L + I EE G E+ ++Y ++DP+DG+ +FI+G P F Sbjct: 62 IADQMAEEAMVSIIFQNLPSHAIYGEEKGWRCKEESADYVWVLDPIDGTKSFITGKPVFG 121 Query: 101 LSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEKPSISFYTRG--- 157 +A+ +P+ I +P++K+ + G+ G+ LNG+ I R + YT Sbjct: 122 TLIALLYKGKPILGLIDQPILKERWIGMNGRRTKLNGEDISTRSCPKLSQAYLYTTSPHL 181 Query: 158 ------KGIELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKE 211 K + + G A LA G +D V++ + L+P D A V + + Sbjct: 182 FSEEAEKAYSRVRDKVKVPLYGCDCYAYALLASGFVDLVIE--SGLKPYDFLALVPVIEG 239 Query: 212 AGALVKDSNGDEI--EVSFSA-TDKVNLVAVNDEELLKMVLSLIE 253 AG + D G E S SA N+VA D ++ + L +E Sbjct: 240 AGGTITDWTGKRFLWEASSSAVATSFNVVAAGDSDIHQQALESLE 284 >gi|7657236 inositol(myo)-1(or 4)-monophosphatase 2 [Homo sapiens] >gi|11424912|ref|XP_008727.1| inositol(myo)-1(or 4)-monophosphatase 2 [Homo sapiens] >gi|3914095|sp|O14732|MYO2_HUMAN MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE 2 (IMPASE 2) (IMP 2) (INOSITOL MONOPHOSPHATASE 2) (MYO-INOSITOL MONOPHOSPHATASE A2) >gi|2406666|gb|AAB70915.1| (AF014398) myo-inositol monophosphatase 2 [Homo sapiens] >gi|5163488|gb|AAD40683.1| (AF157102) myo-inositol monophosphatase 2 [Homo sapiens] Length = 288 Score = 76.5 bits (185), Expect = 3e-13 Identities = 54/191 (28%), Positives = 93/191 (48%), Gaps = 26/191 (13%) Query: 80 TVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQR 139 T +IDP+DG+ NF+ P A+S+ +E + IY ++LY G G+GA+ NGQR Sbjct: 97 TWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQR 156 Query: 140 IKV------------RKLGEK---PSISFYTRGKGIELLNHVKR--TRTLGAIALELAYL 182 ++V ++G K ++ + +E L H K R +G+ L L +L Sbjct: 157 LRVSGETDLSKALVLTEIGPKRDPATLKLFL--SNMERLLHAKAHGVRVIGSSTLALCHL 214 Query: 183 ARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVNDE 242 A GA D L D+AA +I +EAG +V D++G +++ +VA + Sbjct: 215 ASGAADAYYQFG--LHCWDLAAATVIIREAGGIVIDTSGGPLDLM-----ACRVVAASTR 267 Query: 243 ELLKMVLSLIE 253 E+ ++ ++ Sbjct: 268 EMAMLIAQALQ 278 >gb|AAF07824.1|AF200432_1 (AF200432) brain myo-inositol monophosphatase A2b; IMPase A2b [Homo sapiens] Length = 261 Score = 76.5 bits (185), Expect = 3e-13 Identities = 54/191 (28%), Positives = 93/191 (48%), Gaps = 26/191 (13%) Query: 80 TVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQR 139 T +IDP+DG+ NF+ P A+S+ +E + IY ++LY G G+GA+ NGQR Sbjct: 70 TWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQR 129 Query: 140 IKV------------RKLGEK---PSISFYTRGKGIELLNHVKR--TRTLGAIALELAYL 182 ++V ++G K ++ + +E L H K R +G+ L L +L Sbjct: 130 LRVSGETDLSKALVLTEIGPKRDPATLKLFL--SNMERLLHAKAHGVRVIGSSTLALCHL 187 Query: 183 ARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVNDE 242 A GA D L D+AA +I +EAG +V D++G +++ +VA + Sbjct: 188 ASGAADAYYQFG--LHCWDLAAATVIIREAGGIVIDTSGGPLDLM-----ACRVVAASTR 240 Query: 243 ELLKMVLSLIE 253 E+ ++ ++ Sbjct: 241 EMAMLIAQALQ 251 >gb|AAD50453.1|AF170704_3 (AF170704) SpcA [Streptomyces spectabilis] Length = 264 Score = 75.7 bits (183), Expect = 5e-13 Identities = 59/199 (29%), Positives = 93/199 (46%), Gaps = 16/199 (8%) Query: 37 SPSGDETKVVDKVAENVVVSKFKALGVN--IVSEEMGVIEQGSEYTVLIDPLDGSYNFIS 94 S + D D+ +E VV A + I+ EE G GS +IDPLDG+ NF+S Sbjct: 42 SSAKDLVTAFDRGSEACVVEILTAARPDDGILGEEGGERPGGSGVRWVIDPLDGTANFVS 101 Query: 95 GIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNG------------QRIKV 142 G P F +S+A + +Y+P ++ + I G+GA +G Q + Sbjct: 102 GYPAFVVSIAAERAGRTEVGVVYDPSRRETFTAIRGRGAARDGLPLTVSGAERLEQALVS 161 Query: 143 RKLGEKPSISFYTRGKGIELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDI 202 P+ ++ V+ R+ G+ AL+L ++A G LD + + R D Sbjct: 162 TGFSSDPATRDRQAALAARVVARVRDIRSSGSAALDLCWVAAGRLDAYYE--SGTRLWDR 219 Query: 203 AAGVIIAKEAGALVKDSNG 221 AAG +IA+EAGA V ++G Sbjct: 220 AAGALIAEEAGAWVGGADG 238 >sp|P74158|SUHB_SYNY3 EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG >gi|7429924|pir||S75686 suppressor protein suhB - Synechocystis sp. (strain PCC 6803) >gi|1653332|dbj|BAA18247.1| (D90912) extragenic suppressor SuhB [Synechocystis sp.] Length = 287 Score = 74.9 bits (181), Expect = 8e-13 Identities = 62/241 (25%), Positives = 112/241 (45%), Gaps = 20/241 (8%) Query: 3 VKAWRKIALDIINDFDQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKALG 62 ++ W +IA + + + L+G + + G +GD D+ AE +++ K Sbjct: 14 LQTWLEIATEAVLAAGAEIFSLWGKVQQIQEKG--RAGDLVTEADRQAEAIILEIIKRRC 71 Query: 63 VN--IVSEEMGVIEQ-GSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEP 119 + I++EE G + Q + + IDPLDG+ NF P +S+ + + P +Y P Sbjct: 72 PDHAILAEESGQLGQVDNPFCWAIDPLDGTTNFAHSYPVSCVSIGLLIQDIPTVGVVYNP 131 Query: 120 VVKKLYEGIPGQGAYLNGQRIKVRKLGEKPSISF-----YTRGKGIE-------LLNHVK 167 ++L+ GA LN + I+V Y R K ++ L H+ Sbjct: 132 FRQELFRAATSLGATLNRRPIQVSTTASLDKSLLVTGFAYDRVKTLDNNYPEFCYLTHLT 191 Query: 168 R-TRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEV 226 + R G+ A++L +A G LDG + + P D+AAG++I +EAG +V + +++ Sbjct: 192 QGVRRSGSAAIDLIDVACGRLDGYWE--RGINPWDMAAGIVIVREAGGIVSAYDCSPLDL 249 Query: 227 S 227 S Sbjct: 250 S 250 >gb|AAF51693.1| (AE003594) CG9391 gene product [Drosophila melanogaster] Length = 278 Score = 73.4 bits (177), Expect = 3e-12 Identities = 53/182 (29%), Positives = 88/182 (48%), Gaps = 16/182 (8%) Query: 59 KALGVNIVSEEMGVIEQGSEYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYE 118 K +G S GV + E T +IDP+DG+ NF+ P +SV + + +Y Sbjct: 68 KFIGEEESSGAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYN 127 Query: 119 PVVKKLYEGIPGQGAYLNGQRIKV---RKLGEKPSISFY--TRGKGIELLNH-------- 165 P++++ + G GA+ NG+RI V ++LG+ S + TR + + H Sbjct: 128 PILEQRFTARRGHGAFYNGRRIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEKMAK 187 Query: 166 -VKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEI 224 R LG+ AL ++ +A GA D + + D+ AG +I +EAG +V D G E Sbjct: 188 KAHGLRVLGSAALNMSMVALGAADANYEFG--IHAWDVCAGDLIVREAGGVVIDPAGGEF 245 Query: 225 EV 226 ++ Sbjct: 246 DI 247 >gb|AAD21685.1| (AC004793) Contains similarity to gi|1653332 extragenic suppressor (SuhB) from Synechocystis sp. gb|D90912 and is a member of the Inositol monophophatase family PF|00459. EST gb|AA597395 comes from this gene. [Arabidopsis thaliana] Length = 353 Score = 72.6 bits (175), Expect = 4e-12 Identities = 68/226 (30%), Positives = 104/226 (45%), Gaps = 38/226 (16%) Query: 45 VVDKVAENVVVSKFKALGVN--IVSEEMGVI-EQGSEYTVLIDPLDGSYNFISGIPFFAL 101 + DK +E ++ K + I+ EE G+I + S+Y IDPLDG+ NF G P FA+ Sbjct: 95 ITDKASEAAILEVVKKNFSDHLILGEEGGIIGDSSSDYLWCIDPLDGTTNFAHGYPSFAV 154 Query: 102 SVAIFKGEEPVYAFIYEPV------VKKLYEGIPGQGAYLNGQRIKVRK----------- 144 SV + P A + E V + + G GA NGQ+I V K Sbjct: 155 SVGVLYRGNPAAASVVEFVGGPMCWNTRTFSATAGGGALCNGQKIHVSKTDAVERALLIT 214 Query: 145 -LGEKPSISFYTRGKGIELLNHVKR-TRTLGAIALELAYLARGALDGVVDIRNYLRPTDI 202 G + ++ T + + V R R LGA A+++ ++A G + + R L+P D+ Sbjct: 215 GFGYEHDDAWSTNMELFKEFTDVSRGVRRLGAAAVDMCHVALGIAESYWEYR--LKPWDM 272 Query: 203 AAGVI----------IAKEAGALVKDSNGDEIEVSFSATDKVNLVA 238 AAGV+ I +EAG V +G + FS D+ LV+ Sbjct: 273 AAGVLSLIHVRKWTQIVEEAGGAVTRMDGGK----FSVFDRSVLVS 314 >gb|AAF49559.1| (AE003529) CG17027 gene product [Drosophila melanogaster] Length = 288 Score = 72.2 bits (174), Expect = 6e-12 Identities = 59/192 (30%), Positives = 87/192 (44%), Gaps = 27/192 (14%) Query: 80 TVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQR 139 T +IDP+DG+ NFI IP +S+ + ++ V I PV KKL+ GQGA+ NG+ Sbjct: 93 TWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVINNPVQKKLFTTKLGQGAFCNGKP 152 Query: 140 IKVRKLGEKPSISFYTRGKGIELLN-------HVKRTRTLG----------AIALELAYL 182 I V S+ + LL+ H+KR +G + EL + Sbjct: 153 IHVSSC---ESVKDANVAYEVSLLHVHSVANKHIKRIYHVGLNARRLVAYSCVVDELCMV 209 Query: 183 ARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVNDE 242 A G LD Y P D AAG ++ KEAG +V G ++ K +L+ E Sbjct: 210 AAGNLDAFYIEDMY--PWDCAAGSLLVKEAGGVVTHPFGGPFDIM-----KPDLICAGTE 262 Query: 243 ELLKMVLSLIEK 254 +L K + L+ K Sbjct: 263 KLRKEIEDLLRK 274 >gb|AAF63339.1|AF244574_2 (AF244574) myo-inositol-1-monophosphotase [Streptomyces spectabilis] Length = 265 Score = 71.8 bits (173), Expect = 7e-12 Identities = 57/194 (29%), Positives = 91/194 (46%), Gaps = 16/194 (8%) Query: 37 SPSGDETKVVDKVAENVVVSKFKALGVN--IVSEEMGVIEQGSEYTVLIDPLDGSYNFIS 94 S + D D+ +E VV A + I+ EE G GS +IDPLDG+ NF+S Sbjct: 42 SSAKDLVTAFDRRSEACVVEILTAARPDDGILGEEGGERPGGSGVRWVIDPLDGTANFVS 101 Query: 95 GIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNG------------QRIKV 142 G P F +S+A + +++P ++ + I G+GA +G Q + Sbjct: 102 GYPAFVVSIAAEREGRTEAGVVHDPSRRETFTAIRGRGAARDGLPLTVSGAERLEQALVS 161 Query: 143 RKLGEKPSISFYTRGKGIELLNHVKRTRTLGAIALELAYLARGALDGVVDIRNYLRPTDI 202 P+ +++ V+ R+ G+ AL+L ++A G LD + + R D Sbjct: 162 TGFSSDPATRDRQAALAARVVSRVRDIRSSGSAALDLCWVAAGRLDAYYE--SDTRLWDR 219 Query: 203 AAGVIIAKEAGALV 216 AAG +IA+EAGA V Sbjct: 220 AAGALIAEEAGAWV 233 >sp|P46813|SUHB_MYCLE EXTRAGENIC SUPPRESSOR PROTEIN SUHB HOMOLOG >gi|699191|gb|AAA62956.1| (U15181) myo-inositol-1(OR 4)-monophosphatase [Mycobacterium leprae] Length = 291 Score = 71.4 bits (172), Expect = 1e-11 Identities = 61/215 (28%), Positives = 97/215 (44%), Gaps = 25/215 (11%) Query: 26 GDARAGETVGISPSGDETKVVDKVAENVVVSKFKAL--GVNIVSEEMG-----VIEQGSE 78 G A G S D VVD E ++ + L G +I+ EE G Sbjct: 39 GAAGGGAVRAKSTPTDPVTVVDTETERLLRDRLAQLRPGDSILGEEGGGPADLTATPADT 98 Query: 79 YTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQ 138 T ++DP+DG+ NF+ GIP +A+SVA V + E V +++ G GA++ + Sbjct: 99 VTWVLDPIDGTVNFVYGIPAYAVSVAAQVDGVSVAGAVAEVVAGRVHSAASGLGAHVTDE 158 Query: 139 -RIKVRKLGEKPSISFYTRGKGI---------------ELLNHVKRTRTLGAIALELAYL 182 ++V + +S G G ++L V+ R +G+ AL+L + Sbjct: 159 YGVQVLRCSAVDDLSMALLGTGFAYSVVRRAAQAALLAQMLPVVRDVRRIGSAALDLCMV 218 Query: 183 ARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVK 217 A G LD + + ++ D AAG +IA EAGA V+ Sbjct: 219 AAGQLDAYYE--HEVQVWDCAAGALIAAEAGACVQ 251 >gb|AAB94817.1| (AF005905) inositol monophosphate phosphatase [Mycobacterium smegmatis] Length = 276 Score = 71.4 bits (172), Expect = 1e-11 Identities = 58/222 (26%), Positives = 99/222 (44%), Gaps = 22/222 (9%) Query: 18 DQNVMPLFGDARAGETVGISPSGDETKVVDKVAENVVVSKFKALGVNIVSEEMGVIEQGS 77 D +P RA V + T+V + VV + +A G+ + EE G S Sbjct: 24 DAASVPFVAGHRADSAVRKQGNDFATEVDLAIERQVVRALTEATGIGVHGEEFGGEPIDS 83 Query: 78 EYTVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNG 137 ++DP+DG++N+ +G P A+ + + EPV + P + Y + G Y +G Sbjct: 84 PLVWVLDPIDGTFNYAAGSPMAAILLGLLADGEPVAGLTWLPFTGEKYSALVGGPLYSDG 143 Query: 138 QRIKVRKLGEK---------PSISFYTRGK-----GIELLNHV----KRTRTLGAIALEL 179 + LG + + +RG+ +E+L ++ R R GA ++L Sbjct: 144 K--PCPPLGSPTLADSIIGIQTFNIDSRGRFPGRYRVEVLANLSRVCSRVRMHGATGVDL 201 Query: 180 AYLARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNG 221 AY+A G L G + +++ D AAGV + + AG +V D G Sbjct: 202 AYVAAGILGGAISFGHHI--WDHAAGVALVRAAGGVVTDLTG 241 >pir||S24343 myo-inositol-1(or 4)-monophosphatase (EC 3.1.3.25) - African clawed frog >gi|64854|emb|CAA46486.1| (X65513) inositol monophosphatase [Xenopus laevis] Length = 284 Score = 71.0 bits (171), Expect = 1e-11 Identities = 57/210 (27%), Positives = 95/210 (45%), Gaps = 29/210 (13%) Query: 36 ISPSGDETKVVDKVAENVVVS-KFKALGVNIVSEEMGVIEQGSEYTV----LIDPLDGSY 90 ++P+ T KV E ++ S K K + + EE GS T +IDP+DG+ Sbjct: 40 LAPADLVTATDQKVEEMIISSIKEKYPSHSFIGEESVAAGAGSTLTDNPTWIIDPIDGTT 99 Query: 91 NFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKV-------- 142 NF+ PF A+S+ ++ + +Y V K+Y G G+G++ NGQ+++V Sbjct: 100 NFVHRFPFVAVSIGFAVHKQVEFGVVYSCVEDKMYTGRKGKGSFCNGQKLQVSGQKDITK 159 Query: 143 ----RKLGEKPSISFYTRGKGIELLN-------HVKRTRTLGAIALELAYLARGALDGVV 191 +LG + F K + L N + R +G A+ + +A G D Sbjct: 160 SMIITELGSNRNPEFI---KTVSLSNMERLLCIPIHGIRAVGTAAVNMCLVATGGADAYY 216 Query: 192 DIRNYLRPTDIAAGVIIAKEAGALVKDSNG 221 ++ L D+AA +I EAG + D+ G Sbjct: 217 EMG--LHCWDMAAASVIVTEAGGTILDATG 244 >sp|P29219|MYOP_XENLA MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE (IMPASE) (IMP) (INOSITOL MONOPHOSPHATASE) Length = 285 Score = 71.0 bits (171), Expect = 1e-11 Identities = 57/210 (27%), Positives = 95/210 (45%), Gaps = 29/210 (13%) Query: 36 ISPSGDETKVVDKVAENVVVS-KFKALGVNIVSEEMGVIEQGSEYTV----LIDPLDGSY 90 ++P+ T KV E ++ S K K + + EE GS T +IDP+DG+ Sbjct: 40 LAPADLVTATDQKVEEMIISSIKEKYPSHSFIGEESVAAGAGSTLTDNPTWIIDPIDGTT 99 Query: 91 NFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKV-------- 142 NF+ PF A+S+ ++ + +Y V K+Y G G+G++ NGQ+++V Sbjct: 100 NFVHRFPFVAVSIGFAVHKQVEFGVVYSCVEDKMYTGRKGKGSFCNGQKLQVSGQKDITK 159 Query: 143 ----RKLGEKPSISFYTRGKGIELLN-------HVKRTRTLGAIALELAYLARGALDGVV 191 +LG + F K + L N + R +G A+ + +A G D Sbjct: 160 SMIITELGSNRNPEFI---KTVSLSNMERLLCIPIHGIRAVGTAAVNMCLVATGGADAYY 216 Query: 192 DIRNYLRPTDIAAGVIIAKEAGALVKDSNG 221 ++ L D+AA +I EAG + D+ G Sbjct: 217 EMG--LHCWDMAAASVIVTEAGGTILDATG 244 >sp|P20456|MYOP_BOVIN MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE (IMPASE) (IMP) (INOSITOL MONOPHOSPHATASE) (LITHIUM-SENSITIVE MYO-INOSITOL MONOPHOSPHATASE A1) >gi|108813|pir||A35223 myo-inositol-1(or 4)-monophosphatase (EC 3.1.3.25) - bovine >gi|163225|gb|AAA30589.1| (J05394) inositol monophosphatase [Bos taurus] Length = 277 Score = 69.9 bits (168), Expect = 3e-11 Identities = 57/211 (27%), Positives = 98/211 (46%), Gaps = 24/211 (11%) Query: 37 SPSGDETKVVDKVAENVVVS-KFKALGVNIVSEEMGVIEQGS----EYTVLIDPLDGSYN 91 SP+ T KV + ++ S K K + + EE + S T +IDP+DG+ N Sbjct: 38 SPADLVTATDQKVEKMLITSIKEKYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTN 97 Query: 92 FISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRKLGEKPSI 151 F+ G PF A+S+ ++ + +Y + K+Y G G+GA+ NGQ+++V E + Sbjct: 98 FVHGFPFVAVSIGFVVNKKMEFGIVYSCLEDKMYTGRKGKGAFCNGQKLQVSH-QEDITK 156 Query: 152 SFYTRGKGIE--------LLNHVKR--------TRTLGAIALELAYLARGALDGVVDIRN 195 S G +L++++R R +G AL + +A GA D ++ Sbjct: 157 SLLVTELGSSRTPETVRIILSNIERLLCLPIHGIRGVGTAALNMCLVAAGAADAYYEMG- 215 Query: 196 YLRPTDIAAGVIIAKEAGALVKDSNGDEIEV 226 + D+A II EAG ++ D G ++ Sbjct: 216 -IHCWDVAGAGIIVTEAGGVLLDVTGGPFDL 245 >sp|O55023|MYOP_MOUSE MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE (IMPASE) (IMP) (INOSITOL MONOPHOSPHATASE) (LITHIUM-SENSITIVE MYO-INOSITOL MONOPHOSPHATASE A1) >gi|2801801|gb|AAB97469.1| (AF042730) lithium-sensitive myo-inositol monophosphatase A1 [Mus musculus] Length = 277 Score = 69.9 bits (168), Expect = 3e-11 Identities = 60/238 (25%), Positives = 103/238 (43%), Gaps = 28/238 (11%) Query: 37 SPSGDETKVVDKVAENVVVSKFKALGV--NIVSEEMGVIEQGSEYTV----LIDPLDGSY 90 S D V D+ E +++S K + + EE + + +T IDP+DG+ Sbjct: 37 SSPADLVTVTDQKVEKMLMSSIKEKYPCHSFIGEESVAAGEKTVFTESPTWFIDPIDGTT 96 Query: 91 NFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQRIKVRK------ 144 NF+ PF A+S+ +E + +Y V K+Y G G+GA+ NGQ+++V + Sbjct: 97 NFVHRFPFVAVSIGFLVNKEMEFGIVYSCVEDKMYTGRKGKGAFCNGQKLQVSQQEDITK 156 Query: 145 ------LGE--KPSISFYTRGKGIELLN-HVKRTRTLGAIALELAYLARGALDGVVDIRN 195 LG KP +L + + R++G A+ + +A G D ++ Sbjct: 157 SLLVTELGSSRKPETLRIVLSNMEKLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMG- 215 Query: 196 YLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVNDEELLKMVLSLIE 253 + D+A II EAG ++ D G ++ ++A N L K + IE Sbjct: 216 -IHCWDMAGAGIIVTEAGGVLMDVTGGPFDLM-----SRRIIAANSITLAKRIAKEIE 267 >gb|AAF49562.1| (AE003529) CG17026 gene product [Drosophila melanogaster] Length = 284 Score = 68.7 bits (165), Expect = 6e-11 Identities = 58/193 (30%), Positives = 85/193 (43%), Gaps = 29/193 (15%) Query: 80 TVLIDPLDGSYNFISGIPFFALSVAIFKGEEPVYAFIYEPVVKKLYEGIPGQGAYLNGQR 139 T +IDP+DG+ NFI IP ++S+ + ++ V + P KLY GQGA+ NG+ Sbjct: 93 TWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVVNNPAQNKLYTAKLGQGAFCNGKP 152 Query: 140 IKVRK--------------LGEKPSISFYTRGKGIELLNHV----KRTRTLGAIALELAY 181 I+V L P I R K I+ + HV +R A+ L Sbjct: 153 IQVSSCEHLNDANVAYEVCLLHAPKI----RNKHIKRIYHVGSNARRLLAYSAVVDSLCM 208 Query: 182 LARGALDGVVDIRNYLRPTDIAAGVIIAKEAGALVKDSNGDEIEVSFSATDKVNLVAVND 241 +A G LD Y P D AAG ++ +EAG +V G ++ K +L+ Sbjct: 209 VAAGNLDAFHIEDMY--PWDCAAGYLLIREAGGVVTHPYGGPFDIM-----KPDLICAGT 261 Query: 242 EELLKMVLSLIEK 254 E L + LI K Sbjct: 262 ETLRAEIEHLIRK 274 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.317 0.139 0.381 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88993280 Number of Sequences: 2977 Number of extensions: 3741032 Number of successful extensions: 9682 Number of sequences better than 1.0e-10: 48 Number of HSP's better than 0.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 9612 Number of HSP's gapped (non-prelim): 50 length of query: 254 length of database: 189,106,746 effective HSP length: 58 effective length of query: 196 effective length of database: 154,394,500 effective search space: 30261322000 effective search space used: 30261322000 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 164 (68.3 bits)