BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0190 (PAB0190) DE:ATP-dependent RNA helicase, EIF-4A FAMILY
         (752 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||D75219 ATP-dependent RNA helicase, eif-4a family PAB0190 - ...  1465  0.0
pir||D71203 probable ATP-dependent RNA helicase - Pyrococcus hor...  1146  0.0
gi|11499053 ATP-dependent RNA helicase, putative [Archaeoglobus ...   699  0.0
pir||E69055 ATP-dependent RNA helicase, eIF-4A family - Methanob...   611  e-173
pir||H64487 eIF-4A family probable ATP-dependent RNA helicase ho...   608  e-173
sp|Q58900|YF05_METJA PUTATIVE ATP-DEPENDENT RNA HELICASE MJ1505 ...   607  e-172
gb|AAG20456.1| (AE005118) ATP-dependent RNA helicase homolog eIF...   548  e-155
emb|CAC12619.1| (AL445067) RNA helicase (RIG-I) related protein ...   342  6e-93
gb|AAC62691.1| (AF083071) ATP-dependent RNA helicase [Cenarchaeu...   303  6e-81
pir||T31323 ATP-dependent RNA helicase, eIF-4A family - Cenarcha...   294  2e-78
pir||T39190 probable ATP-dependent RNA helicase - fission yeast ...   242  1e-62
gb|AAF55897.1| (AE003735) CG7922 gene product [Drosophila melano...   235  2e-60
gb|AAF79368.1|AC007887_27 (AC007887) F15O4.40 [Arabidopsis thali...   205  2e-51
gi|6322192 Mph1p [Saccharomyces cerevisiae] >gi|731905|sp|P40562...   192  1e-47
pir||C71203 probable DNA excision repair protein - Pyrococcus ho...   157  4e-37
gi|7657516 RNA helicase [Homo sapiens] >gi|4405795|gb|AAD19826.1...   155  2e-36
pir||C72622 hypothetical protein APE1436 - Aeropyrum pernix (str...   153  8e-36
gi|11545922 melanoma differentiation associated protein-5 [Homo ...   143  9e-33
gb|AAK41026.1| RNA helicase (ATP dependent)/eIF4A (eiF4A) [Sulfo...   141  3e-32
emb|CAB57574.1| (Y18930) ATP-dependent RNA helicase, eIF-4A fami...   141  3e-32
gb|AAG09428.1|AF181119_1 (AF181119) RNA helicase [Sus scrofa]         132  1e-29
dbj|BAB13818.1| (AK021416) unnamed protein product [Homo sapiens]     131  2e-29
gi|11499994 DNA repair protein, putative [Archaeoglobus fulgidus...   119  1e-25
sp|Q09884|YC9A_SCHPO HYPOTHETICAL HELICASE C584.10C IN CHROMOSOM...   113  6e-24
pir||T32534 hypothetical protein F15B10.2 - Caenorhabditis elega...   111  2e-23
gi|4885217 excision repair cross-complementing rodent repair def...    98  5e-19
sp|Q92889|XPF_HUMAN DNA-REPAIR PROTEIN COMPLEMENTING XP-F CELL (...    98  5e-19
gb|AAB07689.1| (U64315) DNA repair endonuclease subunit [Homo sa...    95  3e-18
dbj|BAA89229.1| (AB017635) ERCC4 [Cricetulus griseus]                  91  5e-17
gb|AAC03240.1| (AC004155) ERCC4_MOUSE [Mus musculus]                   89  2e-16
gi|7657064 excision repair cross-complementing rodent repair def...    89  2e-16
pir||T46312 hypothetical protein DKFZp434J1111.1 - human (fragme...    87  5e-16
gi|11526480 RNA helicase [Homo sapiens]                                86  1e-15
gb|AAF01274.1|AF160500_1 (AF160500) repair endonuclease [Arabido...    83  1e-14
dbj|BAA28847.1| (AB009461) MUS38 [Neurospora crassa]                   82  2e-14
gb|AAF81910.1|AF277377_1 (AF277377) 5' repair endonuclease [Arab...    80  7e-14
gb|AAF45938.1| (AE003430) mei-9 gene product [Drosophila melanog...    77  6e-13
sp|Q24087|MEI9_DROME MEI-9 PROTEIN (MEIOTIC-9 PROTEIN) >gi|21336...    75  2e-12
emb|CAB70217.1| (AL033535) Similarity to Yeast DNA repair protei...    75  3e-12
pir||T18568 hypothetical protein VF13D12L.2 - Caenorhabditis ele...    75  3e-12
dbj|BAB13422.1| (AB046816) KIAA1596 protein [Homo sapiens]             75  4e-12
dbj|BAA31233.1| (D89592) rhlE [Vibrio alginolyticus]                   72  3e-11
pir||B72707 hypothetical protein APE1073 - Aeropyrum pernix (str...    72  3e-11
sp|P42305|DEAD_BACSU COLD-SHOCK DEAD-BOX PROTEIN A HOMOLOG (ATP-...    71  3e-11
gi|6325235 UV endonuclease; Rad1p [Saccharomyces cerevisiae] >gi...    70  7e-11

>pir||D75219 ATP-dependent RNA helicase, eif-4a family PAB0190 - Pyrococcus
           abyssi (strain Orsay) >gi|5457712|emb|CAB49203.1|
           (AJ248283) ATP-dependent RNA helicase, EIF-4A FAMILY
           [Pyrococcus abyssi]
           Length = 752
           
 Score = 1465 bits (3751), Expect = 0.0
 Identities = 752/752 (100%), Positives = 752/752 (100%)

Query: 1   MNTMYLRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGKVLM 60
           MNTMYLRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGKVLM
Sbjct: 1   MNTMYLRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGKVLM 60

Query: 61  LAPTKPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLL 120
           LAPTKPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLL
Sbjct: 61  LAPTKPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLL 120

Query: 121 TGKINLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVL 180
           TGKINLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVL
Sbjct: 121 TGKINLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVL 180

Query: 181 RNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAG 240
           RNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAG
Sbjct: 181 RNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAG 240

Query: 241 LIESASADLPKKEILRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSAL 300
           LIESASADLPKKEILRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSAL
Sbjct: 241 LIESASADLPKKEILRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSAL 300

Query: 301 RVYLKKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLS 360
           RVYLKKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLS
Sbjct: 301 RVYLKKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLS 360

Query: 361 KKENSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFAR 420
           KKENSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFAR
Sbjct: 361 KKENSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFAR 420

Query: 421 GEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTR 480
           GEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTR
Sbjct: 421 GEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTR 480

Query: 481 DEAYYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREG 540
           DEAYYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREG
Sbjct: 481 DEAYYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREG 540

Query: 541 VKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRL 600
           VKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRL
Sbjct: 541 VKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRL 600

Query: 601 FDQVKRLKDSYPRPVVIVEGQLYGIRNVHPNAIRGAIASIVIDFGVPIIFSSNPEETANY 660
           FDQVKRLKDSYPRPVVIVEGQLYGIRNVHPNAIRGAIASIVIDFGVPIIFSSNPEETANY
Sbjct: 601 FDQVKRLKDSYPRPVVIVEGQLYGIRNVHPNAIRGAIASIVIDFGVPIIFSSNPEETANY 660

Query: 661 IFFMARREQEERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSVERVF 720
           IFFMARREQEERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSVERVF
Sbjct: 661 IFFMARREQEERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSVERVF 720

Query: 721 TASVPELMKVEGIGEKIAREIRRVITSPYTED 752
           TASVPELMKVEGIGEKIAREIRRVITSPYTED
Sbjct: 721 TASVPELMKVEGIGEKIAREIRRVITSPYTED 752


>pir||D71203 probable ATP-dependent RNA helicase - Pyrococcus horikoshii
           >gi|3258336|dbj|BAA31019.1| (AP000007) 650aa long
           hypothetical ATP-dependent RNA helicase [Pyrococcus
           horikoshii]
           Length = 650
           
 Score = 1146 bits (2931), Expect = 0.0
 Identities = 566/655 (86%), Positives = 626/655 (95%), Gaps = 5/655 (0%)

Query: 1   MNTMYLRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGKVLM 60
           MN MY+RK+LLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRL+KYGGKVLM
Sbjct: 1   MNLMYIRKDLLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLDKYGGKVLM 60

Query: 61  LAPTKPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLL 120
           LAPTKPLVLQHAETFRKFF LPPEKIVALTGE+SP+ERV+AW RAKV+IATPQT+ENDLL
Sbjct: 61  LAPTKPLVLQHAETFRKFFTLPPEKIVALTGEISPNERVRAWARAKVVIATPQTIENDLL 120

Query: 121 TGKINLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVL 180
            G+I+LEDV L+IFDEAHRAVGNYAYVYIA+EYL QAKNPHVIGLTASPGS+ EKI+EVL
Sbjct: 121 VGRISLEDVTLIIFDEAHRAVGNYAYVYIAKEYLKQAKNPHVIGLTASPGSTPEKIMEVL 180

Query: 181 RNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAG 240
           RNLGIEHIEYRSENSPDVKPYVQGIKFEW+KVELP LYKEVRKLLRDMLRDSLKPLAEAG
Sbjct: 181 RNLGIEHIEYRSENSPDVKPYVQGIKFEWVKVELPELYKEVRKLLRDMLRDSLKPLAEAG 240

Query: 241 LIESASADLPKKEILRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSAL 300
           L++S SAD+PKKEILRAGQIINEE AKGNHDLRKLLLFHAMALKLHHAIELLETQGLSAL
Sbjct: 241 LLDSTSADIPKKEILRAGQIINEEMAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSAL 300

Query: 301 RVYLKKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLS 360
           RVYLK+LYEEAK GSTRASKELFLD+RMKKALALLIQAKELGIDHPKMEVLK L++EQL 
Sbjct: 301 RVYLKRLYEEAKAGSTRASKELFLDKRMKKALALLIQAKELGIDHPKMEVLKGLIREQLK 360

Query: 361 KKENSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFAR 420
           +KENSKIIVFTNYRETA+KVVEEL K+GIKA+RFVGQA++ENDRGMSQ+EQKLILD+FAR
Sbjct: 361 RKENSKIIVFTNYRETAKKVVEELMKDGIKARRFVGQASRENDRGMSQKEQKLILDAFAR 420

Query: 421 GEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTR 480
            EFNVLVATSVGEEGLDVPEVDLV+FYEPVPSAIRSVQRRGRTGRQKPGRVVIL+AQGTR
Sbjct: 421 SEFNVLVATSVGEEGLDVPEVDLVIFYEPVPSAIRSVQRRGRTGRQKPGRVVILMAQGTR 480

Query: 481 DEAYYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREG 540
           DEAYYWSS+ KE+ MRETIRMVSQ +++E+QLSLESYVK++  +E++ E+K     E  G
Sbjct: 481 DEAYYWSSRQKEKIMRETIRMVSQMVRKERQLSLESYVKREVNEEIKEEKK-----ETGG 535

Query: 541 VKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRL 600
           +KVV+DSRELRSEVVK+LKTLG+KIEV+TLDVGDYI+S++VAIERKSANDFIQSIIDGRL
Sbjct: 536 IKVVIDSRELRSEVVKKLKTLGIKIEVRTLDVGDYIVSEDVAIERKSANDFIQSIIDGRL 595

Query: 601 FDQVKRLKDSYPRPVVIVEGQLYGIRNVHPNAIRGAIASIVIDFGVPIIFSSNPE 655
           FDQVKRLK++YPRPV+I+EGQLYGIRNVHPNAIRGAIASIV+DFGVP+IFSS+ +
Sbjct: 596 FDQVKRLKEAYPRPVIIIEGQLYGIRNVHPNAIRGAIASIVLDFGVPVIFSSSSD 650


>gi|11499053 ATP-dependent RNA helicase, putative [Archaeoglobus fulgidus]
           >gi|7428313|pir||A69432 ATP-dependent RNA helicase
           homolog - Archaeoglobus fulgidus
           >gi|2649107|gb|AAB89786.1| (AE001002) ATP-dependent RNA
           helicase, putative [Archaeoglobus fulgidus]
           Length = 741
           
 Score =  699 bits (1784), Expect = 0.0
 Identities = 370/749 (49%), Positives = 517/749 (68%), Gaps = 28/749 (3%)

Query: 6   LRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGKVLMLAPTK 65
           +++  ++ R+YQ  I A    +N L+V+PTGLGKT IA ++   RL    GKVL LAPTK
Sbjct: 9   IKENTIERRMYQISIAATALTKNTLVVIPTGLGKTTIAALVIASRLLNEDGKVLFLAPTK 68

Query: 66  PLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTGKIN 125
           PLV QHA   ++   +  E+IV+L+GEV P +R + W +A+++++TPQ VENDLL G+I+
Sbjct: 69  PLVEQHARFLKRVLKV--EEIVSLSGEVPPEKRKELWEKARIVVSTPQVVENDLLAGRIS 126

Query: 126 LEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVLRNLGI 185
           LEDV+LV+FDEAHRAVGNYAYV+IA+EYL  AK P ++ +TASPGS  E+I+EV++NLGI
Sbjct: 127 LEDVILVVFDEAHRAVGNYAYVFIAKEYLRTAKKPLILAMTASPGSDPERIMEVIQNLGI 186

Query: 186 EHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAGLIESA 245
           E IE R+E   DV PYV   + EWIKV++P   KEV++ L++ ++   K L E  +    
Sbjct: 187 EAIEVRTEWDSDVAPYVGKKRIEWIKVDIPEEMKEVKERLKECIKIRFKRLRELWI--EV 244

Query: 246 SADLPKKEILRAGQIINEETAKG-NHDLRKLLLFHAMALKLHHAIELLETQGLSALRVYL 304
             +  K+++L   + +  E A   + ++ + L   A  +KL HA+EL+ETQG+ A++ YL
Sbjct: 245 PENSSKRDLLALQEALQAEAASSQSSEIFEALSILAEIMKLQHAVELIETQGVKAVKSYL 304

Query: 305 KKLYEEAKT-GSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKKE 363
           +KL  EA + G ++A+K +  D   KKA+  L + K   ++HPK+E LKE++KEQ  K  
Sbjct: 305 RKLVREATSKGGSKAAKSIVGDPIFKKAVIALSKCK---VEHPKLEKLKEILKEQFEKNP 361

Query: 364 NSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFARGEF 423
           +S++IVFTNYR++A  +V EL+     AK FVGQA+++ND+GM Q+EQ   +D F RG +
Sbjct: 362 DSRVIVFTNYRDSAEMLVNELSPLFPVAK-FVGQASRDNDKGMRQKEQIETIDKFRRGVY 420

Query: 424 NVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEA 483
            VLVATSVGEEGLD+P  DLVVFYE VPS IR++QR+GRTGR + GR+V+L+ +GTRDEA
Sbjct: 421 KVLVATSVGEEGLDIPSTDLVVFYEAVPSEIRAIQRKGRTGRGREGRIVVLVTKGTRDEA 480

Query: 484 YYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREGVKV 543
           YY+SS  KER+M + I  + + I R KQ S+  YV                  E  G+KV
Sbjct: 481 YYYSSMKKERKMYDKILEIKRIIDR-KQRSIGDYVLP----------------EETGIKV 523

Query: 544 VVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIID-GRLFD 602
           +VDSRELRSEVVK L+ +G KIE++ L+V DY++SD VA+ERK+  DF+ SII   RLF 
Sbjct: 524 IVDSRELRSEVVKHLREIGAKIEIRNLEVADYVVSDRVAVERKTVEDFLNSIIQKERLFS 583

Query: 603 QVKRLKDSYPRPVVIVEGQLYGIRNVHPNAIRGAIASIVIDFGVPIIFSSNPEETANYIF 662
           QV RLK +Y RPV+I+EG+ +    VHPNA+RGAIAS++IDFG+P++ SSN  ETA  IF
Sbjct: 584 QVARLKSAYSRPVIIIEGENFYRGGVHPNAVRGAIASLIIDFGIPVLRSSNARETAELIF 643

Query: 663 FMARREQEERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSVERVFTA 722
            MARREQEER+R V     K   TL + Q  IV ++ +V   +A+ LL +F ++E + TA
Sbjct: 644 AMARREQEERKRGVVEHTAKTKRTLKDEQEYIVSAISNVGNVIARNLLDYFQTIENIATA 703

Query: 723 SVPELMKVEGIGEKIAREIRRVITSPYTE 751
              EL KV  +G+KIA+ IRRV+T+PY+E
Sbjct: 704 DEEELAKVPKVGKKIAKRIRRVMTTPYSE 732


>pir||E69055 ATP-dependent RNA helicase, eIF-4A family - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622527|gb|AAB85892.1| (AE000903) ATP-dependent RNA
           helicase, eIF-4A family  [Methanobacterium
           thermoautotrophicum]
           Length = 738
           
 Score =  611 bits (1558), Expect = e-173
 Identities = 327/749 (43%), Positives = 493/749 (65%), Gaps = 37/749 (4%)

Query: 6   LRKELLQPRLYQELIYAKC-KERNCLIVLPTGLGKTIIAMMIADYRLNKY-GGKVLMLAP 63
           ++ E ++ R YQ+L+ A   ++ N +IV PT LGKT++A+++A  RL KY G KVL+L+P
Sbjct: 10  IKPEKIEARTYQQLLAADVIRKGNSMIVAPTALGKTVVAVLVAAERLRKYRGSKVLILSP 69

Query: 64  TKPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTGK 123
           +KPL +QH E+FR+F         +LTG + P ER + W ++++I ATPQTVE+D+L G+
Sbjct: 70  SKPLAIQHEESFREFMLAT---CTSLTGSIKPEERKERWIKSQIISATPQTVESDILAGR 126

Query: 124 INLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVLRNL 183
            +L DV L++FDE HRAVG+Y+YV++A  Y+  A++P ++GLTASPG+ ++KI  V  NL
Sbjct: 127 YDLRDVSLIVFDECHRAVGSYSYVFLASNYIQNARHPLILGLTASPGADEDKIKTVCENL 186

Query: 184 GIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAGLIE 243
            +  +  ++E  PDV+PY++ IK EW+KV +    +++R+LLR +L++ LK L   G+I+
Sbjct: 187 FMNEVVVKTEGDPDVRPYLKPIKIEWVKVRMTPELEDIRELLRKVLKNRLKMLKNLGVID 246

Query: 244 SASADLPKKEILRAGQIINEETAKGNHDLR---KLLLFHAMALKLHHAIELLETQGLSAL 300
           + S  + KK++L+A   +    A+     R   + +   A  + + HA+ELLETQG+  L
Sbjct: 247 TIS--VGKKDLLKARGRVQNRIARSTSPPRACYRAISLLASCINVEHALELLETQGIRPL 304

Query: 301 RVYLKKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLS 360
             YL +L E+     T+A+K L  D    +A+ L  +A   G++HPK++ L E++K +L 
Sbjct: 305 HQYLLRLKEK----KTKAAKGLLADPDFTRAMHLTRRAMMSGVEHPKLDRLMEILKREL- 359

Query: 361 KKENSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFAR 420
           K + ++IIVFT +R+T  ++ +   +EGI A +F GQ ++  ++G++Q++Q+ I+ SF  
Sbjct: 360 KGDEARIIVFTQFRDTLEEIYQRCKREGINAVKFYGQNSRSGEKGLTQKQQRDIIKSFRM 419

Query: 421 GEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTR 480
           G  +VL++TSV EEG+D+P VDLVV YEPVPS IR +QRRGRTGR++ GR+V+LI + TR
Sbjct: 420 GNHDVLLSTSVAEEGIDIPSVDLVVMYEPVPSEIRMIQRRGRTGRKRKGRMVVLITEKTR 479

Query: 481 DEAYYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREG 540
           DEAYY+SS  KER M+E +R  S              V  +    ME           EG
Sbjct: 480 DEAYYYSSIRKERSMKENLRGGS--------------VNVEVNPIME--------PSGEG 517

Query: 541 VKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRL 600
             +  DSRE+ S V++ LK +GV  E+K L VGDY IS++  IERK+  DFI SIID RL
Sbjct: 518 PFIYADSREVNSRVLRELKKIGVDFELKPLAVGDYQISEDTIIERKTTQDFIGSIIDKRL 577

Query: 601 FDQVKRLKDSYPRPVVIVEGQLYGIRNVHPNAIRGAIASIVIDFGVPIIFSSNPEETANY 660
           + Q + +  ++ RPV+I+EG       ++P+A+RGA+A++ +DFG+P+I + + E+TA  
Sbjct: 578 YKQAREMVKNFKRPVMIIEGDDLYSGFINPDAVRGALAAVAVDFGIPVIPTRSAEDTAAM 637

Query: 661 IFFMARREQEERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSVERVF 720
           I  +A REQ E R ++RVR +KK LTL E+Q  IVESLP++ +  A+RLL+ FGSVE V 
Sbjct: 638 IRRIAIREQREGRPDMRVRTDKKPLTLREKQLFIVESLPNIGSKYAERLLEAFGSVEGVM 697

Query: 721 TASVPELMKVEGIGEKIAREIRRVITSPY 749
            AS  EL  VEGIG K A EIRRVI + +
Sbjct: 698 NASEKELRSVEGIGAKRASEIRRVIEAEF 726


>pir||H64487 eIF-4A family probable ATP-dependent RNA helicase homolog -
           Methanococcus jannaschii
           Length = 784
           
 Score =  608 bits (1552), Expect = e-173
 Identities = 338/800 (42%), Positives = 519/800 (64%), Gaps = 76/800 (9%)

Query: 3   TMYLRKELLQP-----RLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGK 57
           TM++   L++P     RLYQ++I A   ++  L VL TGLGKT IA+++    L K  GK
Sbjct: 6   TMFIEHPLIKPKTLEARLYQQIIAANALKKKTLCVLSTGLGKTAIAILVIAGILTKKDGK 65

Query: 58  VLMLAPTKPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVEN 117
           VL+LAP++PLV QH    ++  N+  +KI+ALTG++ P +R + + + K+ IATPQ +EN
Sbjct: 66  VLILAPSRPLVEQHYNRLKQVLNIDEDKIIALTGKIQPKKRAELYKKGKIFIATPQVIEN 125

Query: 118 DLLTGKINLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKIL 177
           D++ G+IN+++ +L+I DEAH   G++AY ++A+++ ++    H++GLTASPGS  +K++
Sbjct: 126 DIIAGRINVDEFILLIADEAHHTTGDHAYAFVAKKFKDKC---HILGLTASPGSDIDKVM 182

Query: 178 EVLRNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLA 237
           E+  NLGIEH+E R+E+  DVKPY+  +K   I+++LP  +K   KL+ + L++ LK L 
Sbjct: 183 EICENLGIEHVEVRTEDDEDVKPYIAKVKLIPIRIDLPNEFKRALKLINEALKERLKILK 242

Query: 238 EAGLIESASADLPKKEILRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGL 297
           +AG+I S  AD+ K E++     +     +  ++L K+    + ALKL HA ELLE+QG 
Sbjct: 243 DAGVINSI-ADVTKTELIELNNKLFSYDEEVKYELIKVC---SEALKLMHAKELLESQGK 298

Query: 298 SALRVYLKKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKE 357
           S    Y+ KL  +     T+++K +  D ++++A+ LL+++    ++HPK+  + ++VK 
Sbjct: 299 SVFLNYINKLSMQ----RTKSAKSIVNDEKVREAVNLLMKS---DVEHPKLGKVVDMVKN 351

Query: 358 QLSKKENSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDS 417
            L K ++ +II+F  YR+T  K+V  LT+ GIKA RF+GQA KE  +GMSQ+EQ   ++ 
Sbjct: 352 ILEKNKDERIIIFAQYRDTVEKIVNLLTQNGIKAIRFIGQANKEG-KGMSQKEQIEAIER 410

Query: 418 FARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQ 477
           F + E +VLV+TSV EEG+D+P V+ ++FYEPVPS IR +QRRGR  R + G+V +LIA+
Sbjct: 411 FKK-EGSVLVSTSVSEEGIDIPSVNYIIFYEPVPSEIRFIQRRGRAMRGEGGKVYVLIAK 469

Query: 478 GTRDEAYYWSSKHKERQM-----------------------RETIRMVSQAIKREKQLSL 514
           GT DEAYY S+ +KER+M                       +E I+  ++ IK EK++  
Sbjct: 470 GTADEAYYRSALYKEREMKRLLKNMCYLLNKRLQKKFEEKSKEEIKEETEEIK-EKEIES 528

Query: 515 ESYVKKDTEKEMER--------------EEKEERKGE-----------REGVKVVVDSRE 549
           ++ VK++T++E E+              E KE  K E           ++ +K++VD RE
Sbjct: 529 KTAVKEETKEEEEKTKKPVTILDFIKQIEVKERSKSEEDKIKQEIKIPKKPIKIIVDVRE 588

Query: 550 LRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRLKD 609
               + K L      IE+KTL+VGDY++SD V +ERK+A DF+ SIID RLF Q+K LK 
Sbjct: 589 --KNMAKLLHNY-ANIELKTLEVGDYVLSDRVVVERKTAEDFVNSIIDKRLFSQLKNLK- 644

Query: 610 SYPRPVVIVEGQLYGIRNVHPNAIRGAIASIVIDFGVPIIFSSNPEETANYIFFMARREQ 669
              +P++IVEG+ +    +H NA++GAI SI++DFG+PIIF+ N EETA+ +  +A +EQ
Sbjct: 645 KVEKPLLIVEGENFS--RLHENALKGAILSIILDFGIPIIFTKNAEETADLLIKIAEKEQ 702

Query: 670 EERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSVERVFTASVPELMK 729
            + +R V VR  K A++L E+Q+ IVESLP V   LA+RLLKHF +VE VFTA   ELMK
Sbjct: 703 IKEKRTVMVRYGKTAMSLKEQQKFIVESLPDVGGALAERLLKHFKTVENVFTAKEEELMK 762

Query: 730 VEGIGEKIAREIRRVITSPY 749
           VEG+G++ A++IR V+T+ Y
Sbjct: 763 VEGVGKERAKKIREVLTAEY 782


>sp|Q58900|YF05_METJA PUTATIVE ATP-DEPENDENT RNA HELICASE MJ1505
           >gi|2826423|gb|AAB99518.1| (U67591) ATP dependent RNA
           helicase, putative  [Methanococcus jannaschii]
           Length = 778
           
 Score =  607 bits (1549), Expect = e-172
 Identities = 335/792 (42%), Positives = 516/792 (64%), Gaps = 71/792 (8%)

Query: 6   LRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGKVLMLAPTK 65
           ++ + L+ RLYQ++I A   ++  L VL TGLGKT IA+++    L K  GKVL+LAP++
Sbjct: 8   IKPKTLEARLYQQIIAANALKKKTLCVLSTGLGKTAIAILVIAGILTKKDGKVLILAPSR 67

Query: 66  PLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTGKIN 125
           PLV QH    ++  N+  +KI+ALTG++ P +R + + + K+ IATPQ +END++ G+IN
Sbjct: 68  PLVEQHYNRLKQVLNIDEDKIIALTGKIQPKKRAELYKKGKIFIATPQVIENDIIAGRIN 127

Query: 126 LEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVLRNLGI 185
           +++ +L+I DEAH   G++AY ++A+++ ++    H++GLTASPGS  +K++E+  NLGI
Sbjct: 128 VDEFILLIADEAHHTTGDHAYAFVAKKFKDKC---HILGLTASPGSDIDKVMEICENLGI 184

Query: 186 EHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAGLIESA 245
           EH+E R+E+  DVKPY+  +K   I+++LP  +K   KL+ + L++ LK L +AG+I S 
Sbjct: 185 EHVEVRTEDDEDVKPYIAKVKLIPIRIDLPNEFKRALKLINEALKERLKILKDAGVINSI 244

Query: 246 SADLPKKEILRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSALRVYLK 305
            AD+ K E++     +     +  ++L K+    + ALKL HA ELLE+QG S    Y+ 
Sbjct: 245 -ADVTKTELIELNNKLFSYDEEVKYELIKVC---SEALKLMHAKELLESQGKSVFLNYIN 300

Query: 306 KLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKKENS 365
           KL  +     T+++K +  D ++++A+ LL+++    ++HPK+  + ++VK  L K ++ 
Sbjct: 301 KLSMQ----RTKSAKSIVNDEKVREAVNLLMKS---DVEHPKLGKVVDMVKNILEKNKDE 353

Query: 366 KIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFARGEFNV 425
           +II+F  YR+T  K+V  LT+ GIKA RF+GQA KE  +GMSQ+EQ   ++ F + E +V
Sbjct: 354 RIIIFAQYRDTVEKIVNLLTQNGIKAIRFIGQANKEG-KGMSQKEQIEAIERFKK-EGSV 411

Query: 426 LVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEAYY 485
           LV+TSV EEG+D+P V+ ++FYEPVPS IR +QRRGR  R + G+V +LIA+GT DEAYY
Sbjct: 412 LVSTSVSEEGIDIPSVNYIIFYEPVPSEIRFIQRRGRAMRGEGGKVYVLIAKGTADEAYY 471

Query: 486 WSSKHKERQM-----------------------RETIRMVSQAIKREKQLSLESYVKKDT 522
            S+ +KER+M                       +E I+  ++ IK EK++  ++ VK++T
Sbjct: 472 RSALYKEREMKRLLKNMCYLLNKRLQKKFEEKSKEEIKEETEEIK-EKEIESKTAVKEET 530

Query: 523 EKEMER--------------EEKEERKGE-----------REGVKVVVDSRELRSEVVKR 557
           ++E E+              E KE  K E           ++ +K++VD RE    + K 
Sbjct: 531 KEEEEKTKKPVTILDFIKQIEVKERSKSEEDKIKQEIKIPKKPIKIIVDVRE--KNMAKL 588

Query: 558 LKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRLKDSYPRPVVI 617
           L      IE+KTL+VGDY++SD V +ERK+A DF+ SIID RLF Q+K LK    +P++I
Sbjct: 589 LHNY-ANIELKTLEVGDYVLSDRVVVERKTAEDFVNSIIDKRLFSQLKNLK-KVEKPLLI 646

Query: 618 VEGQLYGIRNVHPNAIRGAIASIVIDFGVPIIFSSNPEETANYIFFMARREQEERRREVR 677
           VEG+ +    +H NA++GAI SI++DFG+PIIF+ N EETA+ +  +A +EQ + +R V 
Sbjct: 647 VEGENFS--RLHENALKGAILSIILDFGIPIIFTKNAEETADLLIKIAEKEQIKEKRTVM 704

Query: 678 VRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSVERVFTASVPELMKVEGIGEKI 737
           VR  K A++L E+Q+ IVESLP V   LA+RLLKHF +VE VFTA   ELMKVEG+G++ 
Sbjct: 705 VRYGKTAMSLKEQQKFIVESLPDVGGALAERLLKHFKTVENVFTAKEEELMKVEGVGKER 764

Query: 738 AREIRRVITSPY 749
           A++IR V+T+ Y
Sbjct: 765 AKKIREVLTAEY 776


>gb|AAG20456.1| (AE005118) ATP-dependent RNA helicase homolog eIF-4A; Eif4a
           [Halobacterium sp. NRC-1]
           Length = 784
           
 Score =  548 bits (1397), Expect = e-155
 Identities = 312/773 (40%), Positives = 467/773 (60%), Gaps = 41/773 (5%)

Query: 10  LLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRL-NKYGGKVLMLAPTKPLV 68
           +++ R YQ  + A  ++ + L+ LPTGLGKT +++++  YRL +  GG  L+LAPTKPLV
Sbjct: 17  VIEARQYQLQLAAAARQGHTLVCLPTGLGKTTVSLLVTAYRLADDAGGTALLLAPTKPLV 76

Query: 69  LQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTGKINLED 128
            QHA  +R+   +P + +V  TGE  P +R  AW  A+V++ATPQ VENDL+ G+I+++D
Sbjct: 77  EQHAGFYREALAIPDDDVVVFTGETRPDDRRAAWTDARVVVATPQVVENDLVGGRIDMDD 136

Query: 129 VVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVLRNLGIEHI 188
           VV   FDE HRA G+YAY Y+A  Y   A  P V  ++ASPG ++ +I  V  NLG+ ++
Sbjct: 137 VVHCTFDECHRATGDYAYTYVAERYHADAAAPLVTAMSASPGGTEAEIRTVCENLGVGNV 196

Query: 189 EYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAGLIESASAD 248
           E  +E+  DV  +      +W +V LP    EVR  + D++ D L  L E G+ +++S D
Sbjct: 197 EVMTEDDADVGEHTHDTDVQWERVTLPEEILEVRDAINDVIEDRLAKLREIGVTKASSPD 256

Query: 249 LPKKEI----LRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSALRVYL 304
           + +K++     R  Q+I+++ + G   +      HA  +KL  A+EL+ETQ + ++R Y 
Sbjct: 257 ISQKDLNEIRARLQQLIDDDDSDGYQGMS----VHAEVMKLKRAVELVETQSVESVRRYF 312

Query: 305 KKLYEEAKT-GSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKKE 363
           ++    A T G+++AS+ L  +  +K+A+     A+E    HPK    + L+ E L  ++
Sbjct: 313 ERQRNAANTAGASKASQRLVSEPAVKRAMR---TAREFDGLHPKFRQARMLLAETLGIED 369

Query: 364 NSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFARGEF 423
             ++IVFT  R+TA  +   L  E    +RFVGQ   +   GM+Q EQ+  L  F  G+F
Sbjct: 370 GDRVIVFTESRDTAEALTAFL-GEHFDTRRFVGQGDADGSDGMTQTEQRETLAEFRNGDF 428

Query: 424 NVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEA 483
            VLV+TSV EEGLDVPEVDLV+F+EPVP+AIRSVQR+GRTGRQ  GRVV+L+A+ TRDEA
Sbjct: 429 EVLVSTSVAEEGLDVPEVDLVLFFEPVPTAIRSVQRKGRTGRQTAGRVVVLLAEDTRDEA 488

Query: 484 YYWSSKHKERQMRETIR-MVSQAIKREKQL-------SLESYVKKDT----------EKE 525
           Y+W S+ +E++M E ++ +  +A + E +L       +L+ +   +           E  
Sbjct: 489 YFWISRRREQEMTEELQSLKGRADELETELGGDGAQQALDEFGDAEAAGEEPAAPAPEDV 548

Query: 526 MEREEKE----ERKGEREGVKVVVDSRELRSEVVKRL-KTLGVKIEVKTLDVGDYIISDE 580
            + E+ E       G  E V+VVVD REL S + + L K  GV+  ++TL VGDY++SD 
Sbjct: 549 SDGEDTEGVAARVDGAGEAVEVVVDQRELDSTIARELSKRDGVETRLETLAVGDYVVSDR 608

Query: 581 VAIERKSANDFIQSII--DGRLFDQVKRLKDSYPRPVVIVE--GQLYGIRNVHPNAIRGA 636
           VA+ERKS +DF+ +++  +  +F+Q K L   Y RPV++VE  G LY  RNVHPNA+R A
Sbjct: 609 VAVERKSHSDFMDTLLGSERSIFEQAKELARQYTRPVLVVEGDGDLYAERNVHPNAVRSA 668

Query: 637 IASIVIDFGVPIIFSSNPEETANYIFFMARREQEERRREVRVRGEKKALTLAERQRLIVE 696
           +AS+ +D+G+ ++ ++   +T   I  +A REQ    R V   GEK A T  E+Q  +V 
Sbjct: 669 MASLAVDWGLSVMHTNGEGDTTEMIETIAEREQTTNDRAVSAHGEKAAKTQGEQQEYVVS 728

Query: 697 SLPHVSATLAKRLLKHFGSVERVFTASVPELMKVEGIGEKIAREIRRVITSPY 749
           S+  V    A+ LL  FGSVE V TAS  EL   +G+G   A  IR V+ + Y
Sbjct: 729 SITDVGPVTARSLLDTFGSVEAVMTASEDELTAADGVGAVTAERIRGVVGTEY 781


>emb|CAC12619.1| (AL445067) RNA helicase (RIG-I) related protein [Thermoplasma
           acidophilum]
           Length = 508
           
 Score =  342 bits (869), Expect = 6e-93
 Identities = 210/521 (40%), Positives = 311/521 (59%), Gaps = 25/521 (4%)

Query: 10  LLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGKV--LMLAPTKPL 67
           ++QPR YQ  ++     +N LIV+PTGLGKTIIA M  +     YG K   LM+APTKPL
Sbjct: 2   IIQPREYQLNVFKNSIGQNTLIVMPTGLGKTIIAAMFIE---KFYGEKKRSLMVAPTKPL 58

Query: 68  VLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTGKINLE 127
           VLQHA T      +   +I   TGE+   ER   W   K+ ++TPQ V ND+ +G +++ 
Sbjct: 59  VLQHARTIADSTGISENEIGVFTGEIDAEERELIWVTKKIFVSTPQVVFNDMRSGILDIT 118

Query: 128 DVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVLRNLGIEH 187
              L+IFDEAHRAVGNYAYV IA+EYL   K   +IGLTASPGSS+EKI E++ NLGI  
Sbjct: 119 KFDLIIFDEAHRAVGNYAYVDIAQEYLKYKKKL-IIGLTASPGSSREKIDEIMANLGISK 177

Query: 188 IEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAGLIESASA 247
           +  ++E   DV+ YV+ I  + IK+  P   KE+  ++  ++   L+P+  +      S 
Sbjct: 178 VIAKTEMDEDVRKYVKTIDVKLIKIREPDGTKEIVNMIDAVMSKLLEPVKSSNF----SI 233

Query: 248 DLPKKEILRAGQ-IINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSALRVYLKK 306
              +K+++   Q +IN  +AK +  L +L+     A++L +  E +ETQG+     YL++
Sbjct: 234 GRSRKDLVATMQKVIN--SAKEDRSLFQLVRRITAAIRLDYLKEYIETQGIDVALHYLEE 291

Query: 307 LYEEAKTGSTRASKELF-LDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKKENS 365
           + +    G  RA   L  LD        L++ A   G  +PKME    +++  +    N+
Sbjct: 292 MEKSQDPGIRRAISMLSSLDEFATLRTKLMLAAD--GYTNPKMEKTLSIMESNVHG--NA 347

Query: 366 KIIVFTNYRETARKVVEELTKEG--IKAKRFVGQATKENDRGMSQREQKLILDSFARGEF 423
           + IVFT+YR T+  +++ + K G  +K  RF+GQA + +D G+SQ +QK I++ F    +
Sbjct: 348 RAIVFTHYRITSDLLMDYIQKNGTSLKPVRFIGQADRGSDEGLSQDQQKKIIEDFKNNVY 407

Query: 424 NVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEA 483
           NVL+ATS+ EEGLD+P+ D V+FYE VPS IR +QR+GRTGR + G+V IL+ + +RD A
Sbjct: 408 NVLIATSIAEEGLDIPDTDFVIFYEAVPSEIRYIQRKGRTGRSRNGQVYILVFENSRDMA 467

Query: 484 YYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKKDTEK 524
           YY+SS  K  +M +TI  +     R++  S E   K D +K
Sbjct: 468 YYYSSIRKVSRMTQTIEDL-----RQESGSDEKEEKSDVQK 503


>gb|AAC62691.1| (AF083071) ATP-dependent RNA helicase [Cenarchaeum symbiosum]
           Length = 503
           
 Score =  303 bits (767), Expect = 6e-81
 Identities = 186/487 (38%), Positives = 276/487 (56%), Gaps = 27/487 (5%)

Query: 5   YLRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGKVLMLAPT 64
           Y+    ++ R YQ  +  +    NC++VLPTGLGKT +A+ +  + L++ G   L LAPT
Sbjct: 10  YVEPGAVERRDYQVGLAEQAIRENCIVVLPTGLGKTAVALQVISHYLDE-GRGALFLAPT 68

Query: 65  KPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTGKI 124
           + LV QH +   +   +    I  +TGE +   R KAW    VI ATP+   ND+  G +
Sbjct: 69  RVLVNQHRQFLGRALTI--SDITLVTGEDTVPRRKKAWG-GSVICATPEITRNDIARGMV 125

Query: 125 NLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVLRNLG 184
            LE   LV+FDEAHRAVG+YAY  IAR      +N  +IG+TA+  S +EK  E++  L 
Sbjct: 126 PLEQFGLVVFDEAHRAVGDYAYSAIARAV---GENSRMIGMTATLPSEREKADEIMGTLL 182

Query: 185 IEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAGLIES 244
            + I  R+E+ PDVKPYVQ  + EWIKVELP   KE++KLL+  L +    L   G    
Sbjct: 183 SKSIAQRTEDDPDVKPYVQETETEWIKVELPPEMKEIQKLLKMALDERYAALKRCGY--- 239

Query: 245 ASADLPKKEILRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSALRVYL 304
              DL     L A   +      GN    K L     A+++ +A+ + E  G++    + 
Sbjct: 240 ---DLGSNRSLSALLRLRMVVLSGNRRAAKPLF---TAIRITYALNIFEAHGVTPFLKFC 293

Query: 305 KKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKKEN 364
           ++  ++   G     +E   DR    A+A    A+  G++HPK+  L+E V+        
Sbjct: 294 ERTVKKKGAGVAELFEE---DRNFTGAMARAKAAQAAGMEHPKIPKLEEAVRGA-----K 345

Query: 365 SKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFARGEFN 424
            K +VFT+YR++   +  +L   GI +   +G+A    ++G+ Q++Q   +  F  G ++
Sbjct: 346 GKALVFTSYRDSVDLIHSKLQAAGINSGILIGKA---GEKGLKQKKQVETVAKFRDGGYD 402

Query: 425 VLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEAY 484
           VLV+T VGEEGLD+ EV+LVVFY+ VPS+IR VQRRGRTGR+  G++V+L+A+GT DEAY
Sbjct: 403 VLVSTRVGEEGLDISEVNLVVFYDNVPSSIRYVQRRGRTGRKDAGKLVVLMAKGTIDEAY 462

Query: 485 YWSSKHK 491
           YW  + K
Sbjct: 463 YWIGRRK 469


>pir||T31323 ATP-dependent RNA helicase, eIF-4A family - Cenarchaeum symbiosum
           >gi|3599409|gb|AAC62714.1| (AF083072) ATP-dependent RNA
           helicase [Cenarchaeum symbiosum]
           Length = 502
           
 Score =  294 bits (745), Expect = 2e-78
 Identities = 182/487 (37%), Positives = 272/487 (55%), Gaps = 27/487 (5%)

Query: 5   YLRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGKVLMLAPT 64
           Y+    ++ R YQ  +  +    NC++VLPTGLGKT +A+ +  + L++ G   L LAPT
Sbjct: 10  YIEPGAVERRDYQVGLAEQAIRENCIVVLPTGLGKTAVALQVIAHYLDE-GRGALFLAPT 68

Query: 65  KPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTGKI 124
           + LV QH +   +   +    I  +TGE +   R KAW    VI ATP+   ND+  G +
Sbjct: 69  RVLVNQHRQFLGRALTI--SDITLVTGEDTIPRRKKAWG-GSVICATPEIARNDIERGLV 125

Query: 125 NLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVLRNLG 184
            LE   LVIFDEAHRAVG+YAY  IAR       N  ++G+TA+  S +EK  E++  L 
Sbjct: 126 PLEQFGLVIFDEAHRAVGDYAYSSIARAV---GDNSRMVGMTATLPSEREKADEIMGTLL 182

Query: 185 IEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAGLIES 244
              I  R+E+ PDVKPYVQ    EWIKV+LP   KE+++LL+  L +    L   G    
Sbjct: 183 SRSIAQRTEDDPDVKPYVQETATEWIKVDLPPEMKEIQRLLKLALDERYSSLKRCGY--- 239

Query: 245 ASADLPKKEILRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSALRVYL 304
              DL     L A   +      GN    K L     A+++ +A+ + E  G++    + 
Sbjct: 240 ---DLGSNRSLSALLRLRMVVLGGNRRAAKPLF---TAIRITYALNIFEAHGVTPFLKFC 293

Query: 305 KKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKKEN 364
           ++  ++   G     ++   DR    A+A    A+  G++HPK+  L++ V+        
Sbjct: 294 ERTSKKKGVGVAELFEQ---DRNFTGAIARAKAAQAAGMEHPKIPKLEDAVRGA-----R 345

Query: 365 SKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFARGEFN 424
            K +VFT+YR++   +   L   GI +   +G+A    ++G+ QR+Q   +  F  G ++
Sbjct: 346 GKALVFTSYRDSVDLIHSRLKAAGINSGILIGKA---GEKGLKQRKQVETVAKFRDGGYD 402

Query: 425 VLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEAY 484
           VLV+T VGEEGLD+ EV+LV+FY+ VPS+IR VQRRGRTGR+  GR+++L+A+GT DEAY
Sbjct: 403 VLVSTRVGEEGLDISEVNLVIFYDNVPSSIRYVQRRGRTGRKDAGRLIVLMAKGTIDEAY 462

Query: 485 YWSSKHK 491
           YW  + K
Sbjct: 463 YWIGRRK 469


>pir||T39190 probable ATP-dependent RNA helicase - fission yeast
           (Schizosaccharomyces pombe) >gi|6014424|emb|CAB57423.1|
           (AL121764) putative ATP-dependent RNA helicase
           [Schizosaccharomyces pombe]
           Length = 839
           
 Score =  242 bits (611), Expect = 1e-62
 Identities = 169/557 (30%), Positives = 285/557 (50%), Gaps = 21/557 (3%)

Query: 14  RLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGGK-VLMLAPTKPLVLQHA 72
           R YQ  I  K    N L+ LPTGLGKT IA ++    L  +    ++ +APTKPLV Q  
Sbjct: 74  RDYQFNIVQKALFENVLVALPTGLGKTFIAAVVMMNYLRWFPKSYIVFMAPTKPLVTQQM 133

Query: 73  ETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTGKINLEDVVLV 132
           E   K   +P  +   L+G V  + R + +    V   TPQT+ ND+  G  +   +  +
Sbjct: 134 EACYKITGIPKSQTAELSGHVPVTTRNQYYQSRNVFFVTPQTILNDIKHGICDRTRISCL 193

Query: 133 IFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVLRNLGIEHIEYRS 192
           + DEAHR+ GNYAYV +        KN  ++ L+A+PG+  E I  V+ +L I  IE R+
Sbjct: 194 VIDEAHRSTGNYAYVEVVHLLSLSNKNFRILALSATPGNKLEAIQNVIDSLHISRIEIRT 253

Query: 193 ENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAGLIESASA-DLPK 251
           ENS D+  YVQ  + ++  V+L     ++R     +L   L+ L +       +A D+  
Sbjct: 254 ENSIDISQYVQKKEVDFFPVDLSAEITDIRDRFSSILEPMLQKLNKGNYYRIQNAKDITS 313

Query: 252 KEILRAGQ---IINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSALRVYLKKLY 308
             +++A Q    ++ +    N     L  F A+A    + + LL   G+      L+++ 
Sbjct: 314 FTVVQAKQAFLAMSGQNFPANQKWDILNTFDALA-TFAYPLNLLLNHGIRPFYQKLREVE 372

Query: 309 EEAKTGSTRASKELFLD---RRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKKE-- 363
           EE   G +   K +      R +   + +L++ +   + HPK+E L+ +V E   K++  
Sbjct: 373 EECFVGRSGYKKRIINHENYRPLMDDIEILLRDQSF-VGHPKLEHLERIVTEYFEKEQTK 431

Query: 364 NSKIIVFTNYRETARKVVEELTK--EGIKAKRFVGQATKENDRGMSQREQKLILDSFARG 421
           +++I++F   R +A +++  L K    ++   F+GQ+      GMSQ+ Q   +  F +G
Sbjct: 432 DTRIMIFVEIRSSAEEILRFLGKFYPNVRPAIFIGQSAVRKAAGMSQKLQNETVKQFQKG 491

Query: 422 EFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRD 481
           E N L+ATS+GEEGLD+ EVD+++ Y+   S IR +QR GRTGR++ G + +L+ +G ++
Sbjct: 492 EVNTLIATSIGEEGLDIGEVDMIICYDASASPIRMLQRMGRTGRKRKGYIYMLLTRG-KE 550

Query: 482 EAYYWSSKHKERQMRETIRMVSQAIKREKQLSLESY-VKKDTEKEMEREEKEERKGEREG 540
           EA +  +K   R +++ I        R   LS +SY +  +  + +  +   E   E E 
Sbjct: 551 EAKWERAKDAYRTLQDNI-----VSGRGLSLSEKSYRILPEKFRPVCDKRVIEIPKENEE 605

Query: 541 VKVVVDSRELRSEVVKR 557
           V V     +LR+++ K+
Sbjct: 606 VVVAPKKVQLRTKIKKK 622


>gb|AAF55897.1| (AE003735) CG7922 gene product [Drosophila melanogaster]
           Length = 1383
           
 Score =  235 bits (592), Expect = 2e-60
 Identities = 167/558 (29%), Positives = 279/558 (49%), Gaps = 42/558 (7%)

Query: 14  RLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKY--GGKVLMLAPTKPLVLQH 71
           R YQ+ I      +N L+VLPTGLGKT IA ++  Y   ++   GK++ +APT+PLV Q 
Sbjct: 59  RSYQQTIVQSALFKNTLVVLPTGLGKTFIAAVVM-YNFYRWYPKGKIVFMAPTRPLVSQQ 117

Query: 72  AETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTG----KINLE 127
               +K    P E  V LTG++   +R + W   +V  ATPQ V +D+L           
Sbjct: 118 IHASQKIMPFPSEDTVQLTGQLPRPKRAELWASKRVFFATPQVVHSDMLEADGECSFPFG 177

Query: 128 DVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVLRNLGIEH 187
            + L++ DEAHRA G YAY  +A   + + +   ++ L+A+PG + E +  V RNL I +
Sbjct: 178 SIKLIVVDEAHRAKGRYAYTQVADCLMARNRYFRMLALSATPGRTMEDVAAVCRNLYISN 237

Query: 188 IEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAGLIESASA 247
           ++ R + S DV+PY+       I V L    KE R+ L  ++   L+ L EA + +    
Sbjct: 238 LQVRWDTSIDVQPYIHRRTIRTIVVSLKERIKEPRERLLQIIEPYLRQLMEAEIFKGNKG 297

Query: 248 DLPKKEILRAGQIINEETAKGNH--DLRKLLLFHAMALKLHHAIELLETQGLSALRVYL- 304
            + +  +L   +   E +A+G    D   ++   AM + ++H+++L+E  G   LRV++ 
Sbjct: 298 TVSRNSLLFEQKSFVERSAQGQRHPDHNIIMGNFAMCISMYHSLDLMERHG---LRVFVN 354

Query: 305 --------KKLYEEAKTGSTRASKELFLDRRMKKALALLIQA----------KELGIDHP 346
                   ++ +  A+ G+ R   E          L     A           +L   H 
Sbjct: 355 NFDADDDGREKFVLARDGNLRNLVEQVRQELGANPLDYTTHAMTNGEVPPLPSDLDFGHA 414

Query: 347 KMEVLKELVKEQLSKKENSKIIVFTNYRETARKVVEELTKEG--IKAKRFVGQ-ATKEND 403
           K E L++++ +      +S+ IVF  YRE+   +   L +    ++ + FVGQ +T    
Sbjct: 415 KYEKLRQVLVQHFQANPDSRAIVFCEYRESVMLIHRLLLQHRPVLRPRCFVGQGSTVGAS 474

Query: 404 RGMSQREQKLILDSFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPV-PSAIRSVQRRGR 462
             ++Q++Q  I+  F  G  NVLVATS+GEEGLDV EV+++V ++    +  R +QR GR
Sbjct: 475 YALTQKQQLQIMTDFRSGTSNVLVATSIGEEGLDVGEVEMIVCFDICSTNPTRFIQRIGR 534

Query: 463 TGRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMVSQAIK-----REKQLSLESY 517
           TGR+K G VV+L+ +G   +       +K++  ++ +   S  +K     +  ++    +
Sbjct: 535 TGRKKNGEVVMLVTEGREQQVLKDVLANKDQINKKLLN--SSVVKLSLYEQNPRMVPSKF 592

Query: 518 VKKDTEKEMEREEKEERK 535
             K  EK ME   +E+ K
Sbjct: 593 QPKCEEKHMEPVAEEKPK 610


>gb|AAF79368.1|AC007887_27 (AC007887) F15O4.40 [Arabidopsis thaliana]
           Length = 1587
           
 Score =  205 bits (515), Expect = 2e-51
 Identities = 164/542 (30%), Positives = 244/542 (44%), Gaps = 102/542 (18%)

Query: 14  RLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKY--GGKVLMLAPTKPLVLQH 71
           R YQ  I       N L+ LPTGLGKT+IA ++  Y   ++   GK++  AP++PLV+Q 
Sbjct: 206 RDYQFAITKTALFSNTLVALPTGLGKTLIAAVVM-YNYFRWFPQGKIVFAAPSRPLVMQQ 264

Query: 72  AETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLLTGKINL----- 126
            E       +P E  + LTG+  PS+R   W   +V   TPQ +E D+ +G         
Sbjct: 265 IEACHNIVGIPQEWTIDLTGQTCPSKRAFLWKSKRVFFVTPQVLEKDIQSGDARFVLKLP 324

Query: 127 --------------EDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSS 172
                           +V ++ DEAHRA+GNY+Y  + RE +       ++ LTA+PGS 
Sbjct: 325 LVHKDCPFSGTCLTNYLVCLVIDEAHRALGNYSYCVVVRELMAVPIQLRILALTATPGSK 384

Query: 173 QEKILEVLRNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGL-----YKEVRKLLRD 227
            + I  ++ NL I  +EYR+E+  DV PYV   K E I+V+   +       +V K L  
Sbjct: 385 TQAIQGIIDNLQISTLEYRNESDHDVCPYVHDRKLEVIEVQAEQVPLGQDADDVSKRLFH 444

Query: 228 MLRDSLKPLAEAGLIESASADLPKKEILRAGQIINEETAKG----NH-DLRKLLLFHAMA 282
           ++R     L   G        L   E+L A     +    G    NH D+       A  
Sbjct: 445 VIRPYAVRLKNFG--------LSPHEVLMARDKFRQAPLPGLPHVNHGDVESCF---AAL 493

Query: 283 LKLHHAIELLETQGLSALRVYLKKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELG 342
           + L+H  +LL + G   +R   + L E+ K G          D RM K   L+ Q    G
Sbjct: 494 ITLYHIRKLLSSHG---IRPAYEMLEEKLKEGPFARLMSKNEDIRMTK--LLMQQRLSHG 548

Query: 343 IDHPKMEVLKEL-------VKEQLSKKENSKIIVFTNYRETA------------------ 377
              PK+  + E+       V  QL  + N  +I+F   R                     
Sbjct: 549 APSPKLSKMLEILVDHFIDVSTQLVLQLNIDMILFYGCRSERSEDITGHYFLKFQRKRKV 608

Query: 378 ---------------------------RKVVEELTKEG--IKAKRFVGQATKENDRGMSQ 408
                                      R ++  L+  G  +KA  F+GQ++ +  +G SQ
Sbjct: 609 SIIVVCFPLFSCSSYFFVSIHPITLLFRDIMNALSNIGDMVKATEFIGQSSGKTLKGQSQ 668

Query: 409 REQKLILDSFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKP 468
           + Q+ +L+ F  G FNV+VATS+GEEGLD+ EVDLV+ ++   S +R +QR GRTGR+  
Sbjct: 669 KIQQAVLEKFRAGGFNVIVATSIGEEGLDIMEVDLVICFDANVSPLRMIQRMGRTGRKNN 728

Query: 469 GR 470
           GR
Sbjct: 729 GR 730


>gi|6322192 Mph1p [Saccharomyces cerevisiae] >gi|731905|sp|P40562|YIS2_YEAST
           PUTATIVE ATP-DEPENDENT RNA HELICASE YIR002C
           >gi|626348|pir||S48436 probable RNA helicase YIR002c -
           yeast (Saccharomyces cerevisiae)
           >gi|557851|emb|CAA86204.1| (Z38062) orf, len: 993, CAI:
           0.16 possible ATP dependent RNA helicase [Saccharomyces
           cerevisiae]
           Length = 993
           
 Score =  192 bits (483), Expect = 1e-47
 Identities = 163/621 (26%), Positives = 288/621 (46%), Gaps = 87/621 (14%)

Query: 3   TMYLRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIA--MMIADYRLNKYGGKVLM 60
           + Y+     + R YQ  I  K   +N L  +PTG+GKT IA  +M+  +R  K   K++ 
Sbjct: 77  SFYVYPTNYEVRDYQYTIVHKSLFQNTLCAIPTGMGKTFIASTVMLNYFRWTKKA-KIIF 135

Query: 61  LAPTKPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVENDLL 120
            APT+PLV Q  +       +P ++   L  + S   R + W   +V  ATPQ VENDL 
Sbjct: 136 TAPTRPLVAQQIKACLGITGIPSDQTAILLDK-SRKNREEIWANKRVFFATPQVVENDLK 194

Query: 121 TGKINLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKNPHVIGLTASPGSSQEKILEVL 180
            G ++ +D+V ++ DEAHRA G+ AY  + +       +  ++ LTA+P S  E + EV+
Sbjct: 195 RGVLDPKDIVCLVIDEAHRATGSSAYTNVVKFIDRFNSSYRLLALTATPASDLEGVQEVV 254

Query: 181 RNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDMLRDSLKPLAEAG 240
            NL I  IE R+E S D+  Y++  K E I+V L    +++ + L   ++  L+   E G
Sbjct: 255 NNLDISKIEIRTEESMDIVKYMKKRKKEKIEVPLLLEIEDIIEQLGMAVKPVLQQAIELG 314

Query: 241 LIESASADLPK--KEILRAGQIINEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLS 298
           + E          K + ++ +II   T       R   +   +   +   ++ L+  G+ 
Sbjct: 315 IYEECDPSQINAFKAMQQSQKIIANPTIPEGIKWRNFFILQLLN-NVGQMLKRLKIYGIR 373

Query: 299 ALRVYLKKLYEE------AKTGSTRASKELFLDRRMK----KALALLIQAKELGIDHPKM 348
               Y +    E       K  + + + E +    +K    +    L   K +G  H K+
Sbjct: 374 TFFNYFQNKCTEFTTKYNLKKSTNKIAAEFYYHPILKNIKNQCENYLSDPKFVG--HGKL 431

Query: 349 EVLKELVKEQLSKK-ENSKIIVFTNYRETARKVV---EELTKEGIKAKRFVGQATKE--- 401
           + +++ + +   K+  +S++I+FT  RE+A ++V   + +  + I+   F+GQA  +   
Sbjct: 432 QCVRDELMDFFQKRGSDSRVIIFTELRESALEIVKFIDSVADDQIRPHIFIGQARAKEGF 491

Query: 402 --------------------------------------NDR--------GMSQREQ---- 411
                                                 ND+        G S+  Q    
Sbjct: 492 DEVKYTRKHAPKGRKKVERLHRQEQEKFLEAERTKRAANDKLERSARRTGSSEEAQISGM 551

Query: 412 -----KLILDSFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQ 466
                K ++ +F +GE+NVLV TS+GEEGLD+ EVDL++ Y+   S I+++QR GRTGR+
Sbjct: 552 NQKMQKEVIHNFKKGEYNVLVCTSIGEEGLDIGEVDLIICYDTTSSPIKNIQRMGRTGRK 611

Query: 467 KPGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMVSQAI--KREKQLSLESYVKKDTEK 524
           + G++V+L +    +E+Y +    ++    + + +  Q I  K+  ++  E  + +  E 
Sbjct: 612 RDGKIVLLFSS---NESYKFERAMEDYSTLQAL-ISKQCIDYKKSDRIIPEDIIPECHET 667

Query: 525 EMEREEKEERKGEREGVKVVV 545
            +   ++ E   E E V  V+
Sbjct: 668 LITINDENEIINEMEDVDEVI 688


>pir||C71203 probable DNA excision repair protein - Pyrococcus horikoshii
           >gi|3258335|dbj|BAA31018.1| (AP000007) 90aa long
           hypothetical DNA excision repair protein [Pyrococcus
           horikoshii]
           Length = 90
           
 Score =  157 bits (393), Expect = 4e-37
 Identities = 78/89 (87%), Positives = 87/89 (97%)

Query: 664 MARREQEERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSVERVFTAS 723
           MA+REQEER+REVR+RGEKKALTLAERQR+IVESLP+VS TLA+RLL+HFGSVE+VFTAS
Sbjct: 1   MAKREQEERKREVRIRGEKKALTLAERQRMIVESLPNVSTTLARRLLRHFGSVEKVFTAS 60

Query: 724 VPELMKVEGIGEKIAREIRRVITSPYTED 752
           VPELMKVEGIGEKIAREIRRVITSPY E+
Sbjct: 61  VPELMKVEGIGEKIAREIRRVITSPYIEE 89


>gi|7657516 RNA helicase [Homo sapiens] >gi|4405795|gb|AAD19826.1| (AF038963)
           RNA helicase [Homo sapiens]
           Length = 925
           
 Score =  155 bits (387), Expect = 2e-36
 Identities = 149/571 (26%), Positives = 262/571 (45%), Gaps = 52/571 (9%)

Query: 12  QPRLYQ-ELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYG----GKVLMLAPTKP 66
           +PR YQ EL     K +N +I  PTG GKT ++++I ++ L K+     GKV+  A   P
Sbjct: 242 KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIP 301

Query: 67  LVLQHAETFRKFFNLPPEKIVALTGEVS---PSERVKAWNRAKVIIATPQTVENDLLTGK 123
           +  Q    F K+F     ++  ++G  +   P E++   N   +II TPQ + N+L  G 
Sbjct: 302 VYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENN--DIIILTPQILVNNLKKGT 359

Query: 124 I-NLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKN------PHVIGLTASPGSSQEK- 175
           I +L    L+IFDE H     + Y  I   YL+Q         P VIGLTAS G    K 
Sbjct: 360 IPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASVGVGDAKN 419

Query: 176 -------ILEVLRNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEVRKLLRDM 228
                  I ++  +L    I     N  +++  V   +  + KVE   +  + + ++  +
Sbjct: 420 TDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVE-SRISDKFKYIIAQL 478

Query: 229 LRDS-------LKPLAEAGLIESASADLPKKE-----ILRAGQIIN-EETAKGNHDLRKL 275
           +RD+        K L     I++      K E     + +A  +    +  + +   + L
Sbjct: 479 MRDTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKAL 538

Query: 276 LLFHAMALKLHHAIELLETQGLSALRVYLKKLYEEAKTGSTRASKELFLDRRMKKALALL 335
            L+ +   K + A+ + E   +     YLK  +   +       ++    R  +K   L 
Sbjct: 539 FLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFEEIEQDLTQRFEEKLQELE 598

Query: 336 IQAKELGIDHPKMEVLKELVKEQLSKKENSKIIVFTNYR---ETARKVVEELTKEG-IKA 391
             +++   ++PK+E L  +++E+      +  I+F   R   +  +  +E   K   +K 
Sbjct: 599 SVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKP 658

Query: 392 KRFVGQATKENDRGMSQREQKLILDSF-ARGEFNVLVATSVGEEGLDVPEVDLVVFYEPV 450
               G+     + GM+   QK ILD+F A G+ N+L+ATSV +EG+D+ + +LV+ YE V
Sbjct: 659 GILTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYV 718

Query: 451 PSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMV---SQAIK 507
            + I+ +Q RGR GR +  +  +L +     E     + +KE+ M ++I  +    +A+ 
Sbjct: 719 GNVIKMIQTRGR-GRARGSKCFLLTSNAGVIEKEQ-INMYKEKMMNDSILRLQTWDEAVF 776

Query: 508 REKQLSL---ESYVKKDTEKEMEREEKEERK 535
           REK L +   E +++   EK     +KE +K
Sbjct: 777 REKILHIQTHEKFIRDSQEKPKPVPDKENKK 807


>pir||C72622 hypothetical protein APE1436 - Aeropyrum pernix (strain K1)
           >gi|5105119|dbj|BAA80433.1| (AP000061) 254aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 254
           
 Score =  153 bits (382), Expect = 8e-36
 Identities = 81/209 (38%), Positives = 132/209 (62%), Gaps = 1/209 (0%)

Query: 542 KVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLF 601
           +V VD RE RS V   L++LGV++  K L +GDY++SD + +ERK+++DF +S+ DGRLF
Sbjct: 20  RVYVDVREERSPVPSILESLGVQVIPKQLPMGDYLVSDSIIVERKTSSDFAKSLFDGRLF 79

Query: 602 DQVKRLKDSYPRPVVIVEGQLYGIR-NVHPNAIRGAIASIVIDFGVPIIFSSNPEETANY 660
           +Q  RL + Y    +IVEG     R      ++  A+A++ +D+G+ ++ + +P+ TA  
Sbjct: 80  EQASRLAEHYETVFIIVEGPPVPRRYRGRERSLYAAMAALQLDYGIRLMNTMDPKGTALV 139

Query: 661 IFFMARREQEERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSVERVF 720
           I  +AR    E  + + +  + +   + E Q  I++S P +    A+R+L+ FGS+ER F
Sbjct: 140 IESLARLSTREGGQRIVIHKKPRLSDVREWQLYILQSFPGIGRRTAERILERFGSLERFF 199

Query: 721 TASVPELMKVEGIGEKIAREIRRVITSPY 749
           TAS  E+ KVEGIGEK A EI++++ +PY
Sbjct: 200 TASKAEISKVEGIGEKRAEEIKKILMTPY 228


>gi|11545922 melanoma differentiation associated protein-5 [Homo sapiens]
           >gi|11344594|gb|AAG34368.1|AF095844_1 (AF095844)
           melanoma differentiation associated protein-5 [Homo
           sapiens]
           Length = 1025
           
 Score =  143 bits (356), Expect = 9e-33
 Identities = 179/682 (26%), Positives = 291/682 (42%), Gaps = 137/682 (20%)

Query: 11  LQPRLYQ-ELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYG-----GKVLMLAPT 64
           LQ R YQ E+     + +N +I LPTG GKT +A+ IA   L+K       GKV++L   
Sbjct: 306 LQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNK 365

Query: 65  KPLVLQHAETFRKFFNLPPEK---IVALTGE----VSPSERVKAWNRAKVIIATPQTVEN 117
             LV Q    FRK F    +K   ++ L+G+    +S  E VK+ +   +II+T Q +EN
Sbjct: 366 VLLVEQ---LFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCD---IIISTAQILEN 419

Query: 118 DLLT------GKINLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQA-KN----------- 159
            LL         + L D  L+I DE H       Y  I R YL Q  KN           
Sbjct: 420 SLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVI 479

Query: 160 --PHVIGLTASPG--------SSQEKILEVLRNLGIEHIEYRSENSPDVKPYVQGI--KF 207
             P ++GLTASPG         ++E IL++  NL    I+   EN   +K  +Q    KF
Sbjct: 480 PLPQILGLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKF 539

Query: 208 EWIKVELPGLYKEVRKLLRDMLRDS----LKPLAEAGL--IESASADLPKKEILRAGQII 261
                     +KE  KLL  M R      + P+++ G    E  +  + KK         
Sbjct: 540 AIADATREDPFKE--KLLEIMTRIQTYCQMSPMSDFGTQPYEQWAIQMEKKA-------- 589

Query: 262 NEETAKGNHDLRKLLLFHAMALKLHHAIELLETQGLSALRVYLKKLYEEAKTGSTRA--- 318
                KGN   RK  +      K + A+++ +T  +     +L+  Y E K         
Sbjct: 590 ---AKKGN---RKERVCAEHLRKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIED 643

Query: 319 --------------------SKELFLDRRMKKALALLIQ--------AKELGIDHPKMEV 350
                                K L LD   +  + L  +        A+    ++ K+  
Sbjct: 644 DSDEGGDDEYCDGDEDEDDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTK 703

Query: 351 LKELVKEQLSKKENS-KIIVFTNYRETARKVVEELTKE------GIKAKRFVGQATKEND 403
           L+  + EQ ++ E S + I+FT  R++A  + + +T+       G+KA   +G       
Sbjct: 704 LRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEF 763

Query: 404 RGMSQREQKLILDSFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRT 463
           + M+Q EQK ++  F  G+ N+L+AT+V EEGLD+ E ++V+ Y  V + I  VQ RGR 
Sbjct: 764 KPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGR- 822

Query: 464 GRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKKDTE 523
            R      V++   G+    +   +  +E+ M + I  V       + +  E Y  K  E
Sbjct: 823 ARADESTYVLVAHSGSGVIEHETVNDFREKMMYKAIHCV-------QNMKPEEYAHKILE 875

Query: 524 KEMEREEKEERKGEREGVKVVVDSRELRS----------------EVVKRLKTLGVKIEV 567
            +M+   +++ K +R   K   ++  L +                 V++++  + +  E 
Sbjct: 876 LQMQSIMEKKMKTKRNIAKHYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEF 935

Query: 568 KTLDVGDYIISDEVAIERKSAN 589
           K L    YI+ +  A+++K A+
Sbjct: 936 KEL----YIVRENKALQKKCAD 953


>gb|AAK41026.1| RNA helicase (ATP dependent)/eIF4A (eiF4A) [Sulfolobus
           solfataricus]
           Length = 233
           
 Score =  141 bits (352), Expect = 3e-32
 Identities = 75/215 (34%), Positives = 128/215 (58%), Gaps = 5/215 (2%)

Query: 541 VKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRL 600
           +++  D RE  S + + LK LG+ +    L V DY+I+D+VA+ERKS ND + S+ D R 
Sbjct: 3   IRIYADDREKASGIPELLKELGITVIFSQLTVADYVITDDVAVERKSVNDLVNSVFDKRF 62

Query: 601 FDQVKRLKDSYPRPVVIVEGQLYGIRNVHP--NAIRGAIASIVIDFGVPIIFSSNPEETA 658
           FDQ+ RL + Y  P+++VEG +  IR +     AI  A+ S  ID+ V + +S + ++TA
Sbjct: 63  FDQISRLSEVYRFPILLVEGDINDIRKITEKWRAINNALISATIDYDVKVFYSRDKKDTA 122

Query: 659 NYIFFMARREQ--EERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSV 716
             +  +A + Q  E +   + +  + K  ++++ Q  IVES P+V + LA+RLL  FG++
Sbjct: 123 EVLKKIAEKFQFGENKSNRISLHNKAKLESVSDIQLYIVESFPNVGSILAERLLLKFGTI 182

Query: 717 ERVFTASVPELMKVEGIGEKIAREIRRVITSPYTE 751
           + +  AS+ EL K  G   K A +I +++ + Y++
Sbjct: 183 QNICNASISELEKALG-SRKKAEDIYKILRTHYSK 216


>emb|CAB57574.1| (Y18930) ATP-dependent RNA helicase, eIF-4A family [Sulfolobus
           solfataricus]
           Length = 233
           
 Score =  141 bits (352), Expect = 3e-32
 Identities = 75/215 (34%), Positives = 128/215 (58%), Gaps = 5/215 (2%)

Query: 541 VKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRL 600
           +++  D RE  S + + LK LG+ +    L V DY+I+D+VA+ERKS ND + S+ D R 
Sbjct: 3   IRIYADDREKASGIPELLKELGITVIFSQLTVADYVITDDVAVERKSVNDLVNSVFDKRF 62

Query: 601 FDQVKRLKDSYPRPVVIVEGQLYGIRNVHP--NAIRGAIASIVIDFGVPIIFSSNPEETA 658
           FDQ+ RL + Y  P+++VEG +  IR +     AI  A+ S  ID+ V + +S + ++TA
Sbjct: 63  FDQISRLSEVYRFPILLVEGDINDIRKITEKWRAINNALISATIDYDVKVFYSRDKKDTA 122

Query: 659 NYIFFMARREQ--EERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKHFGSV 716
             +  +A + Q  E +   + +  + K  ++++ Q  IVES P+V + LA+RLL  FG++
Sbjct: 123 EVLKKIAEKFQFGENKSNRISLHNKAKLESVSDIQLYIVESFPNVGSILAERLLLKFGTI 182

Query: 717 ERVFTASVPELMKVEGIGEKIAREIRRVITSPYTE 751
           + +  AS+ EL K  G   K A +I +++ + Y++
Sbjct: 183 QNICNASISELEKALG-SRKKAEDIYKILRTHYSK 216


>gb|AAG09428.1|AF181119_1 (AF181119) RNA helicase [Sus scrofa]
           Length = 940
           
 Score =  132 bits (330), Expect = 1e-29
 Identities = 140/566 (24%), Positives = 254/566 (44%), Gaps = 52/566 (9%)

Query: 11  LQPRLYQ-ELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYG----GKVLMLAPTK 65
           L+PR YQ EL       +N +I  PTG GKT ++++I ++ L K+     GKV+  A   
Sbjct: 239 LKPRKYQLELALPAQNGKNTIICAPTGCGKTFVSLLICEHHLKKFPRGRKGKVVFFAIQL 298

Query: 66  PLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAW-NRAKVIIATPQTVENDLLTGKI 124
           P+  Q    F K F     K+  ++G  S +  V+     + +II TPQ + N L  G I
Sbjct: 299 PVYEQQKSVFSKHFERLGYKVAGISGATSDTVCVEQIVENSDIIILTPQILVNCLTNGTI 358

Query: 125 -NLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKN------PHVIGLTASPG------- 170
            +L    L+IFDE H     + Y  I   YL++         P VIGLTAS G       
Sbjct: 359 PSLSVFTLMIFDECHNTSKQHPYNVIMFSYLDRKLGGSSDSLPQVIGLTASVGVGDAKNK 418

Query: 171 -SSQEKILEVLRNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVEL----------PGLYK 219
             + E I ++  +L    I    +N  +++  V   +  + KVEL            L  
Sbjct: 419 AEATEYICKLCASLDTSVIATVRDNLEELEEVVYKPQKFFRKVELRTTDRFKCIISQLMM 478

Query: 220 EVRKLLRDMLRDSLKPLAEAGLIESASADLPKKEILRAGQIINEETA-------KGNHDL 272
           E+  L + +  + L  +   GL +  +++   ++  +    + +E A            +
Sbjct: 479 EIESLAKSIFEE-LGTITLGGLFQIQNSNFGTQKYEQWIVKVQKECAVFQMPDKDKESRI 537

Query: 273 RKLLLFHAMALKLHH-AIELLETQGLSALRVYLKKLYEEAKTGSTRASKELFLDRRMKKA 331
            K L  +   L++++ A+ + E   +     YLK  +   +       ++    R  +K 
Sbjct: 538 CKALFSYMSHLRIYNDALIINEHARMKDALDYLKDFFRNIRAAGFDEIEQDLTQRFEEKL 597

Query: 332 LALLIQAKELGIDHPKMEVLKELVKEQLSKKENSKIIVFTNYR---ETARKVVEELTKEG 388
             L   + +   ++PK+  L  +++E+      ++ I+F   R   +  +K ++E  K  
Sbjct: 598 QELESISIDPSNENPKLRDLCFILQEEYHLNPETRTILFVKTRALVDALKKWIKENPKLS 657

Query: 389 -IKAKRFVGQATKENDRGMSQREQKLILDSFARGEFN-VLVATSVGEEGLDVPEVDLVVF 446
            +K     G+     + GM+   QK +LD+F   + N +L+ TSV +EG+D+ + +LV+ 
Sbjct: 658 FLKPSILTGRGKTNQNIGMTLPAQKCVLDTFRTDKDNKILITTSVADEGIDIAQCNLVIL 717

Query: 447 YEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMV---S 503
           YE V + I+ +Q RGR GR +  +  +L A     +     + +KE  M   I ++    
Sbjct: 718 YEYVGNVIKMIQTRGR-GRARGSKCFLLTANADLIDKEK-MNMYKEEMMNGAILILQTWD 775

Query: 504 QAIKREK--QLSLESYVKKDTEKEME 527
           +A+ +EK  Q+ +   + +D + + E
Sbjct: 776 EAVFKEKIHQIQIREKIIRDNQGKPE 801


>dbj|BAB13818.1| (AK021416) unnamed protein product [Homo sapiens]
           Length = 678
           
 Score =  131 bits (327), Expect = 2e-29
 Identities = 137/569 (24%), Positives = 254/569 (44%), Gaps = 52/569 (9%)

Query: 11  LQPRLYQ-ELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKY-GGKVLMLAPTKPLV 68
           ++ R YQ E+I    + +N +I LPTG GKT  A  +A   L    G KV++L     LV
Sbjct: 1   MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLV 60

Query: 69  LQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAK-VIIATPQTVENDLLTGK---- 123
            QH E FR+  +     +  L+G++ P        R   ++I T + ++  L + +    
Sbjct: 61  TQHGEEFRRMLD-GRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEH 119

Query: 124 INLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKN-----PHVIGLTASPGSSQEK--- 175
           + L    L++ DE H    +  Y  I  +YL          P V+GLTASPG+       
Sbjct: 120 VELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASKLD 179

Query: 176 -----ILEVLRNLGIEHIEYRSENSPDVKPYVQGI--KFEWIKVELPGLYKEVRKLLRDM 228
                +L++  NL    I       P ++ + Q    ++          + ++ K L D 
Sbjct: 180 GAINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKKLMDQ 239

Query: 229 LRDSLKPLAEAGLIESASADLPKKEILRAGQIINEETAKGNHDLRKLLLFHAM----ALK 284
           + D L+      L       + ++++++    ++E  A      +++   H      AL 
Sbjct: 240 IHDHLEM---PELSRKFGTQMYEQQVVK----LSEAAALAGLQEQRVYALHLRRYNDALL 292

Query: 285 LHHAIELLETQGLSALRVYLKKLYEEAKTGSTRASKEL---FLDRRMKKALALLIQAKEL 341
           +H  +  ++   L+AL+ +  + +   KT    A + L   F DR+ +     L      
Sbjct: 293 IHDTVRAVDA--LAALQDFYHREHV-TKTQILCAERRLLALFDDRKNE-----LAHLATH 344

Query: 342 GIDHPKMEVLKELVKEQLSKKENSKIIVFTNYRETARKVVEELTKE------GIKAKRFV 395
           G ++PK+E+L+++++ Q S   + + I+FT  R++A  ++  L ++       I+A+  +
Sbjct: 345 GPENPKLEMLEKILQRQFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLI 404

Query: 396 GQATKENDRGMSQREQKLILDSFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIR 455
           G         M+QR+Q+ ++  F  G  N+LVATSV EEGLD+P  ++VV Y  + + I 
Sbjct: 405 GAGNSSQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEIS 464

Query: 456 SVQRRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMVSQAIKREKQLSLE 515
            VQ RGR    +      +  +G+R+      ++  E  M + +  V +  + E Q  + 
Sbjct: 465 MVQARGRAWADQ-SVYAFVATEGSRELKRELINEALETLMEQAVAAVQKMDQAEYQAKIR 523

Query: 516 SYVKKDTEKEMEREEKEERKGEREGVKVV 544
              +    K   +  + E + ++  V+ V
Sbjct: 524 DLQQAALTKRAAQAAQRENQRQQFPVEHV 552


>gi|11499994 DNA repair protein, putative [Archaeoglobus fulgidus]
           >gi|7483288|pir||C69552 DNA repair protein homolog -
           Archaeoglobus fulgidus >gi|2650671|gb|AAB91244.1|
           (AE001108) DNA repair protein, putative [Archaeoglobus
           fulgidus]
           Length = 208
           
 Score =  119 bits (295), Expect = 1e-25
 Identities = 76/211 (36%), Positives = 121/211 (57%), Gaps = 17/211 (8%)

Query: 543 VVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISD---EVAIERKSANDFIQSIIDGR 599
           + VDSRE    +V++LK+LG+ + VK L+VGDY+I     EV +ERK  NDFI SIIDGR
Sbjct: 2   IFVDSRE-PERIVEKLKSLGLDVYVKRLEVGDYLIKHSIYEVPVERKDVNDFISSIIDGR 60

Query: 600 LFDQVKRLKDSYPRPVVIVEGQLYGI---RNVHPNAIRGAIASIVIDFG----VPIIFSS 652
           LF Q   L   YP  ++ V G +      R +  +A+ GA+ S+ I       VP++F +
Sbjct: 61  LFRQCHLLSSRYPLSILAVIGDIDEAVEERGISRSAVIGAMVSMAIKNAQGQVVPLVFKN 120

Query: 653 NPEETANYIFFMARREQEERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRLLKH 712
             +      F +A +  + R  +  ++   +  +    +  ++ ++P +    A++LL +
Sbjct: 121 EDD------FCLALKSIDSRVSQGDLKILPRLKSHENPKIAMLTAIPGIGEKKAEKLLDY 174

Query: 713 FGSVERVFTASVPELMKVEGIGEKIAREIRR 743
           FGS++R+  AS+ EL +V+GIGEK AREI R
Sbjct: 175 FGSIQRIANASIAELKRVDGIGEKKAREIYR 205


>sp|Q09884|YC9A_SCHPO HYPOTHETICAL HELICASE C584.10C IN CHROMOSOME III
           >gi|2130449|pir||S62524 probable RNA
           helicase/ribonuclease SPAC8A4.08c - fission yeast
           (Schizosaccharomyces pombe) >gi|7491257|pir||T39130
           hypothetical protein SPAC8A4.08c - fission yeast
           (Schizosaccharomyces pombe) >gi|7493293|pir||T41432
           ribonuclease - fission yeast (Schizosaccharomyces pombe)
           >gi|1052539|emb|CAA91518.1| (Z66569) unknown
           [Schizosaccharomyces pombe] >gi|4456833|emb|CAB37423.1|
           (AL032824) ribonuclease [Schizosaccharomyces pombe]
           Length = 1374
           
 Score =  113 bits (281), Expect = 6e-24
 Identities = 135/542 (24%), Positives = 240/542 (43%), Gaps = 85/542 (15%)

Query: 5   YLRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRL---------NKYG 55
           +L  +LL  R YQ+ +Y    ++N L+V+ TG GKT++A+ +   +L         N   
Sbjct: 6   FLLPQLL--RKYQQDVYNIASKQNTLLVMRTGAGKTLLAVKLIKQKLEEQILIQESNLEH 63

Query: 56  GKVLMLAPTK-PLVLQHAETFRKFFNLPPEKIVALTGEVS--PSERV--KAWNRAKVIIA 110
            K+ +    K PLV Q AE  R      P K+    GE+S   SE++      +  VI+ 
Sbjct: 64  KKISVFLVNKVPLVFQQAEYIRSQL---PAKVGMFYGELSIEMSEQLLTNIILKYNVIVI 120

Query: 111 TPQTVENDLLTGKINLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKN---------PH 161
           T       L  G +++ D+ L+IFDE H A+GN AY  I  ++ ++AK          P 
Sbjct: 121 TADLFYLFLARGFLSINDLNLIIFDECHHAIGNDAYARIMNDFYHRAKAVLSKKHFTLPR 180

Query: 162 VIGLTASPGSSQEKILEVLRNLGIEHIEYRSENSPDVKPYVQGIKFEWIKVELPGLYKEV 221
           + G+TASP + ++          + H  Y+ E   D K +V        + EL   +   
Sbjct: 181 IFGMTASPFTGKKG--------NLYHRLYQWEQLFDSKAHVVS------ENELADYF--- 223

Query: 222 RKLLRDMLRDSLKPLAEAGLIESASADLPKK--EILRAGQIINEETAKGNHDLRKLLLFH 279
                  L +    +    L+   S  + KK  E L+  ++I+        +   + L+ 
Sbjct: 224 ------CLPEESYVMYSNKLVVPPSDSIIKKCEETLQGCKLISRAVKTALAETIDMGLWF 277

Query: 280 AMALKLHHAIELLETQGLSALRVYLKKLYEEAKTGSTRASKELFLDRRMKKALALLIQAK 339
              + L + ++ +ET          K+L ++A        +EL +DR   K      +  
Sbjct: 278 GEQVWL-YLVDFVET----------KRLKKKALGKQLSDDEELAIDR--LKIFVEDWKNN 324

Query: 340 ELGIDHPKMEV------------LKELVKEQLSKKENSKIIVFTNYRETARKV---VEEL 384
           +   + P++ V            L EL+K    K ++ + ++F   + TA  +   ++ L
Sbjct: 325 KYSDNGPRIPVFDSTDVTDKVFKLLELLKATYRKSDSVRTVIFVERKATAFTLSLFMKTL 384

Query: 385 TKEGIKAKRFVGQA-TKENDRGMSQREQKLILDSFARGEFNVLVATSVGEEGLDVPEVDL 443
               I+A  F+G   + + +  M+ R QK  L  F  G++NVL+AT+V EEG+DVP  +L
Sbjct: 385 NLPNIRAHSFIGHGPSDQGEFSMTFRRQKDTLHKFKTGKYNVLIATAVAEEGIDVPSCNL 444

Query: 444 VVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMVS 503
           V+ +    +  + VQ RGR  R    + +I +   T +   +    H+E+ ++  +  +S
Sbjct: 445 VIRFNICRTVTQYVQSRGR-ARAMASKFLIFL--NTEELLIHERILHEEKNLKFALSELS 501

Query: 504 QA 505
            +
Sbjct: 502 NS 503


>pir||T32534 hypothetical protein F15B10.2 - Caenorhabditis elegans
           >gi|2662588|gb|AAB88350.1| (AF036696) contains
           similarity to helicases [Caenorhabditis elegans]
           Length = 1037
           
 Score =  111 bits (276), Expect = 2e-23
 Identities = 140/608 (23%), Positives = 245/608 (40%), Gaps = 86/608 (14%)

Query: 4   MYLRKELLQPRLYQELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKYGG-----KV 58
           ++ +++L      +EL     + +N ++  PTG GKT+IA  I               K 
Sbjct: 285 IHRQRQLCLRNYQEELCQVALQGKNTIVTAPTGSGKTVIAANIIKEHFESRSSEGKRFKA 344

Query: 59  LMLAPTKPLVLQHAETFRKFFNLPPEKIVALTGEVSPSERVKAWNRAKVIIATPQTVEND 118
           L + P   ++ Q A +   + +      +    +  P+  V       +I+ATPQ + N 
Sbjct: 345 LFMTPNSMILNQQAASISSYLDHVYHTQIIQGSDNVPTRNVI--QSKDLIVATPQMIVNL 402

Query: 119 LLTGKINLED-----------VVLVIFDEAHRAVGNYAYVYIAREYLNQAKN-------- 159
               + +L+D             ++ FDE H  V N  Y  I REY +  KN        
Sbjct: 403 CNEHRNSLDDESRLDQFFLSTFTIIFFDECHNTVKNSPYSNIMREY-HYLKNMGNMPEGH 461

Query: 160 --PHVIGLTASPGSSQEKILEVLRN--------LGIEHIEYRSENSPDVKPYVQGIKFEW 209
             P +IGLTAS G+  +     +RN        + ++ +    +N  +++ Y   +  + 
Sbjct: 462 SLPQIIGLTASLGTGDKNDCLQVRNYIAGLCASMDVKDLSIVKDNLEELRGYSPIVPDKV 521

Query: 210 IKVE-------------LPGLYKEVRKLLRDMLRDSLKPLAEAGLIESASADLPKKEILR 256
           +  E             L  + +EV  L+R  LR+    + +   IE+   D        
Sbjct: 522 LLCERSTDGPIGMFTNRLTLMMQEVEGLIRTALRNEHIGIEQRRQIETTERDFRPDSSFL 581

Query: 257 AGQIINEETAKGNHDLRKLLLFHAMALK-------LHHAIELLETQGLSAL-------RV 302
                 E     N    ++ L    + +       ++ A+++L+    +          V
Sbjct: 582 DPPADKEHAGYQNWVCNQMNLVSGTSFRETGTRTIINEALDVLKECFCTLSYNINFHPEV 641

Query: 303 YLKKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKK 362
            L  L +E +  +   +  +   R  ++    L+       ++P +    + + EQ  ++
Sbjct: 642 ALNYLKDEMEYRTPNFTVNMI--RIWERYHNQLVGTGSA--ENPMISKTVQYIVEQNLQR 697

Query: 363 ENSKIIVF--TNYRETARKVV----EELTKEGIKAKRFVG---QATKENDRGMSQREQKL 413
            +S+ I+F  T Y  T    V    EEL   GIK++   G         D   S+++Q  
Sbjct: 698 ADSRTIIFVRTRYEATILNKVLNSNEELLMLGIKSEWMSGLNKSTASSADISASKQKQME 757

Query: 414 ILDSFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVI 473
            L  FA GE  +LV+TSV EEGLDVPE  LV+ Y    + I  VQRRGR        V+I
Sbjct: 758 KLKMFADGEIRILVSTSVAEEGLDVPECSLVIKYNYATNEIAHVQRRGRGRALNSECVLI 817

Query: 474 LIAQGTRDEAYYWSSKHKERQMRETIRMVS-------QAIKREKQLSLESYVKKDTEKEM 526
             +   RD+    +++ KE  M ETI ++        + +  E        +++DT+K  
Sbjct: 818 TNSIALRDQES--NNRDKESLMSETISLIQNSPAEFRKCVDEESNKIWPRILREDTDKAQ 875

Query: 527 EREEKEER 534
           + EE+  R
Sbjct: 876 KIEEQINR 883


>gi|4885217 excision repair cross-complementing rodent repair deficiency,
           complementation group 4; Excision-repair, complementing
           defective, in Chinese hamster,; xeroderma pigmentosum,
           complementation group F [Homo sapiens]
           >gi|11430345|ref|XP_007800.1| excision repair
           cross-complementing rodent repair deficiency,
           complementation group 4 [Homo sapiens]
           >gi|1905924|gb|AAB50174.1| (L77890) DNA repair protein
           [Homo sapiens]
           Length = 916
           
 Score = 97.5 bits (239), Expect = 5e-19
 Identities = 81/316 (25%), Positives = 151/316 (47%), Gaps = 31/316 (9%)

Query: 444 VVFYEPVPSAIRSVQ--RRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQ-----MR 496
           VV Y+   + +R ++  R  R G  KP RV  LI  G+ +E  Y ++  KE++     +R
Sbjct: 578 VVLYDAELTFVRQLEIYRASRPG--KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIR 635

Query: 497 ETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREGVK--VVVDSRELRSEV 554
           E   MV    +  +  +    V+     ++  + ++    E+ G +  +VVD RE RSE+
Sbjct: 636 EKASMVVPEEREGRDETNLDLVRGTASADVSTDTRKAGGQEQNGTQQSIVVDMREFRSEL 695

Query: 555 VKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRLKDSYPRP 614
              +   G+ IE  TL+VGDYI++ E+ +ERKS +D I S+ +GRL+ Q   +   Y RP
Sbjct: 696 PSLIHRRGIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRP 755

Query: 615 VVIVE------------GQLYGIRNVHPNAIRGAIASIVIDF-GVPIIFSSNPEETANYI 661
           V+++E            G L+  + +  N I   +  + + F  + I++  +P  TA   
Sbjct: 756 VLLIEFDPSKPFSLTSRGALF--QEISSNDISSKLTLLTLHFPRLRILWCPSPHATAELF 813

Query: 662 FFMAR-REQEERRREVRVRGEKKALTLAER----QRLIVESLPHVSATLAKRLLKHFGSV 716
             + + + Q +    + +  + + L  +E+     +  +  +P V+A   + L+ H  ++
Sbjct: 814 EELKQSKPQPDAATALAITADSETLPESEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNI 873

Query: 717 ERVFTASVPELMKVEG 732
             +   S  EL  + G
Sbjct: 874 AELAALSQDELTSILG 889


>sp|Q92889|XPF_HUMAN DNA-REPAIR PROTEIN COMPLEMENTING XP-F CELL (XERODERMA PIGMENTOSUM
           GROUP F COMPLEMENTING PROTEIN) (DNA EXCISION REPAIR
           PROTEIN ERCC-4)
           Length = 905
           
 Score = 97.5 bits (239), Expect = 5e-19
 Identities = 81/316 (25%), Positives = 151/316 (47%), Gaps = 31/316 (9%)

Query: 444 VVFYEPVPSAIRSVQ--RRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQ-----MR 496
           VV Y+   + +R ++  R  R G  KP RV  LI  G+ +E  Y ++  KE++     +R
Sbjct: 567 VVLYDAELTFVRQLEIYRASRPG--KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIR 624

Query: 497 ETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREGVK--VVVDSRELRSEV 554
           E   MV    +  +  +    V+     ++  + ++    E+ G +  +VVD RE RSE+
Sbjct: 625 EKASMVVPEEREGRDETNLDLVRGTASADVSTDTRKAGGQEQNGTQQSIVVDMREFRSEL 684

Query: 555 VKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRLKDSYPRP 614
              +   G+ IE  TL+VGDYI++ E+ +ERKS +D I S+ +GRL+ Q   +   Y RP
Sbjct: 685 PSLIHRRGIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRP 744

Query: 615 VVIVE------------GQLYGIRNVHPNAIRGAIASIVIDF-GVPIIFSSNPEETANYI 661
           V+++E            G L+  + +  N I   +  + + F  + I++  +P  TA   
Sbjct: 745 VLLIEFDPSKPFSLTSRGALF--QEISSNDISSKLTLLTLHFPRLRILWCPSPHATAELF 802

Query: 662 FFMAR-REQEERRREVRVRGEKKALTLAER----QRLIVESLPHVSATLAKRLLKHFGSV 716
             + + + Q +    + +  + + L  +E+     +  +  +P V+A   + L+ H  ++
Sbjct: 803 EELKQSKPQPDAATALAITADSETLPESEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNI 862

Query: 717 ERVFTASVPELMKVEG 732
             +   S  EL  + G
Sbjct: 863 AELAALSQDELTSILG 878


>gb|AAB07689.1| (U64315) DNA repair endonuclease subunit [Homo sapiens]
           Length = 905
           
 Score = 94.8 bits (232), Expect = 3e-18
 Identities = 80/316 (25%), Positives = 150/316 (47%), Gaps = 31/316 (9%)

Query: 444 VVFYEPVPSAIRSVQ--RRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQ-----MR 496
           VV Y+   + +R ++  R  R G  KP RV  LI  G+ +E  Y ++  KE++     +R
Sbjct: 567 VVLYDAELTFVRQLEIYRASRPG--KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIR 624

Query: 497 ETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREGVK--VVVDSRELRSEV 554
           E   MV    +  +  +    V+     ++  + ++    E+ G +  +VVD RE RSE+
Sbjct: 625 EKASMVVPEEREGRDETNLDLVRGTASADVSTDTRKAGGQEQNGTQQSIVVDMREFRSEL 684

Query: 555 VKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRLKDSYPRP 614
              +    + IE  TL+VGDYI++ E+ +ERKS +D I S+ +GRL+ Q   +   Y RP
Sbjct: 685 PSLIHRRDIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRP 744

Query: 615 VVIVE------------GQLYGIRNVHPNAIRGAIASIVIDF-GVPIIFSSNPEETANYI 661
           V+++E            G L+  + +  N I   +  + + F  + I++  +P  TA   
Sbjct: 745 VLLIEFDPSKPFSLTSRGALF--QEISSNDISSKLTLLTLHFPRLRILWCPSPHATAELF 802

Query: 662 FFMAR-REQEERRREVRVRGEKKALTLAER----QRLIVESLPHVSATLAKRLLKHFGSV 716
             + + + Q +    + +  + + L  +E+     +  +  +P V+A   + L+ H  ++
Sbjct: 803 EELKQSKPQPDAATALAITADSETLPESEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNI 862

Query: 717 ERVFTASVPELMKVEG 732
             +   S  EL  + G
Sbjct: 863 AELAALSQDELTSILG 878


>dbj|BAA89229.1| (AB017635) ERCC4 [Cricetulus griseus]
           Length = 913
           
 Score = 90.9 bits (222), Expect = 5e-17
 Identities = 90/344 (26%), Positives = 151/344 (43%), Gaps = 51/344 (14%)

Query: 318 ASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKKENSKIIVFTNYRETA 377
           A  E FL R  +K      +A+E+ ++  K +  K  +K     K+          R + 
Sbjct: 423 AGAEAFLLRLYRKTFEKDSKAEEVWVNLRKGDGPKRTMKSDKRPKDTKN-----KERAST 477

Query: 378 RKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFARG----------EFNVLV 427
           +K   +  K  +   + +G A +  + G ++ +Q+    S   G          + N+  
Sbjct: 478 KKGAPKRKKRELTLTQVMGTAEEPPEEGAAEEDQQRQATSSPEGCGGEIQHEAFDLNLSS 537

Query: 428 ATSVG--EEGLDV-------------------PEVDLVVFYEPVPSAIRSVQ--RRGRTG 464
            ++ G  +E L +                    E   VV Y+   + +R ++  R  R G
Sbjct: 538 DSAYGILKEPLTIIHPLVGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPG 597

Query: 465 RQKPGRVVILIAQGTRDEAYYWSSKHKERQ-----MRETIRMV---SQAIKREKQLSL-E 515
             KP RV  LI  G+ +E  Y ++  KE++     +RE   MV    +  + E  L L  
Sbjct: 598 --KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLAR 655

Query: 516 SYVKKDTEKEMEREEKEERKGEREGVKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDY 575
             V  D   +  +   +E  G +  +  VVD RE RSE+   +   G+ IE  TL+VGDY
Sbjct: 656 GTVSTDAPADTRKAGGQEHNGTQPSI--VVDMREFRSELPSLIHRRGIDIEPVTLEVGDY 713

Query: 576 IISDEVAIERKSANDFIQSIIDGRLFDQVKRLKDSYPRPVVIVE 619
           I++ E+ +ERKS +D I S+  GRL+ Q   +   Y RPV+++E
Sbjct: 714 ILTPELCVERKSVSDLIGSLNSGRLYSQCLAMSRYYRRPVLLIE 757


>gb|AAC03240.1| (AC004155) ERCC4_MOUSE [Mus musculus]
           Length = 917
           
 Score = 88.5 bits (216), Expect = 2e-16
 Identities = 60/187 (32%), Positives = 98/187 (52%), Gaps = 15/187 (8%)

Query: 444 VVFYEPVPSAIRSVQ--RRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETI-- 499
           VV Y+   + +R ++  R  R G  KP RV  LI  G+ +E  Y ++  KE++  E +  
Sbjct: 579 VVLYDAELTFVRQLEIYRASRPG--KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIR 636

Query: 500 RMVSQAIKREKQLSLESYVKK-------DTEKEMEREEKEERKGEREGVKVVVDSRELRS 552
              S  +  E++   E+ +         D   +  +   +E+ G +  +  VVD RE RS
Sbjct: 637 EKASMVVPEEREGRDETNLDLARGSAALDAPTDTRKAGGQEQNGTQSSI--VVDMREFRS 694

Query: 553 EVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRLKDSYP 612
           E+   +   G+ IE  TL+VGDYI++ E+ +ERKS +D I S+  GRL+ Q   +   Y 
Sbjct: 695 ELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYR 754

Query: 613 RPVVIVE 619
           RPV+++E
Sbjct: 755 RPVLLIE 761


>gi|7657064 excision repair cross-complementing rodent repair deficiency,
           complementation group 4 [Mus musculus]
           >gi|6063149|gb|AAF03157.1|AF189285_1 (AF189285) DNA
           repair endonuclease XPF [Mus musculus]
           Length = 917
           
 Score = 88.5 bits (216), Expect = 2e-16
 Identities = 60/187 (32%), Positives = 98/187 (52%), Gaps = 15/187 (8%)

Query: 444 VVFYEPVPSAIRSVQ--RRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETI-- 499
           VV Y+   + +R ++  R  R G  KP RV  LI  G+ +E  Y ++  KE++  E +  
Sbjct: 579 VVLYDAELTFVRQLEIYRASRPG--KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIR 636

Query: 500 RMVSQAIKREKQLSLESYVKK-------DTEKEMEREEKEERKGEREGVKVVVDSRELRS 552
              S  +  E++   E+ +         D   +  +   +E+ G +  +  VVD RE RS
Sbjct: 637 EKASMVVPEEREGRDETNLDLARGSAALDAPTDTRKAGGQEQNGTQSSI--VVDMREFRS 694

Query: 553 EVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRLKDSYP 612
           E+   +   G+ IE  TL+VGDYI++ E+ +ERKS +D I S+  GRL+ Q   +   Y 
Sbjct: 695 ELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYR 754

Query: 613 RPVVIVE 619
           RPV+++E
Sbjct: 755 RPVLLIE 761


>pir||T46312 hypothetical protein DKFZp434J1111.1 - human (fragment)
           >gi|6808358|emb|CAB70840.1| (AL137608) hypothetical
           protein [Homo sapiens]
           Length = 398
           
 Score = 87.4 bits (213), Expect = 5e-16
 Identities = 71/274 (25%), Positives = 133/274 (47%), Gaps = 13/274 (4%)

Query: 273 RKLLLFHAMALKLHHAIELLETQGLSALRVYLKKLYEEAKTGSTRASKELFLDRRMKKAL 332
           + L L+ +   K + A+ + E   +     YLK  +   +       ++    R  +K  
Sbjct: 9   KALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQ 68

Query: 333 ALLIQAKELGIDHPKMEVLKELVKEQLSKKENSKIIVFTNYR---ETARKVVEELTKEG- 388
            L   +++   ++PK+E L  +++E+      +  I+F   R   +  +  +E   K   
Sbjct: 69  ELESVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSF 128

Query: 389 IKAKRFVGQATKENDRGMSQREQKLILDSF-ARGEFNVLVATSVGEEGLDVPEVDLVVFY 447
           +K     G+     + GM+   QK ILD+F A G+ N+L+ATSV +EG+D+ + +LV+ Y
Sbjct: 129 LKPGILTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILY 188

Query: 448 EPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMV---SQ 504
           E V + I+ +Q RGR GR +  +  +L +     E     + +KE+ M ++I  +    +
Sbjct: 189 EYVGNVIKMIQTRGR-GRARGSKCFLLTSNAGVIEKEQ-INMYKEKMMNDSILRLQTWDE 246

Query: 505 AIKREKQLSL---ESYVKKDTEKEMEREEKEERK 535
           A+ REK L +   E +++   EK     +KE +K
Sbjct: 247 AVFREKILHIQTHEKFIRDSQEKPKPVPDKENKK 280


>gi|11526480 RNA helicase [Homo sapiens]
           Length = 590
           
 Score = 86.2 bits (210), Expect = 1e-15
 Identities = 63/179 (35%), Positives = 89/179 (49%), Gaps = 17/179 (9%)

Query: 12  QPRLYQ-ELIYAKCKERNCLIVLPTGLGKTIIAMMIADYRLNKY----GGKVLMLAPTKP 66
           +PR YQ EL     K +N +I  PTG GKT ++++I ++ L K+     GKV+  A   P
Sbjct: 242 KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIP 301

Query: 67  LVLQHAETFRKFFNLPPEKIVALTG---EVSPSERVKAWNRAKVIIATPQTVENDLLTGK 123
           +  Q    F K+F     ++  ++G   E  P E++   N   +II TPQ + N+L  G 
Sbjct: 302 VYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENN--DIIILTPQILVNNLKKGT 359

Query: 124 I-NLEDVVLVIFDEAHRAVGNYAYVYIAREYLNQAKN------PHVIGLTASPGSSQEK 175
           I +L    L+IFDE H     + Y  I   YL+Q         P VIGLTAS G    K
Sbjct: 360 IPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASVGVGDAK 418


>gb|AAF01274.1|AF160500_1 (AF160500) repair endonuclease [Arabidopsis thaliana]
           >gi|9759161|dbj|BAB09717.1| (AB010072) repair
           endonuclease [Arabidopsis thaliana]
           Length = 956
           
 Score = 83.1 bits (202), Expect = 1e-14
 Identities = 81/347 (23%), Positives = 152/347 (43%), Gaps = 39/347 (11%)

Query: 436 LDVPEVDLVVFYEPVPSAIRSVQ-RRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQ 494
           LD+ +  +++ Y P    +R ++  +     +K     I   + T  + +  S + +   
Sbjct: 612 LDILKPSVIIVYHPDMGFVRELEVYKAENPLRKLKVYFIFYDESTEVQKFEASIRRENEA 671

Query: 495 MRETIRMVSQAIKREKQLSL-------ESYVKKDTEKEMEREEKEERKGEREGVKVVVDS 547
               IR  S  I    Q  L         +    T+  + R+    ++ E+E  +V+VD 
Sbjct: 672 FESLIRQKSSMIIPVDQDGLCMGSNSSTEFPASSTQNSLTRKAGGRKELEKE-TQVIVDM 730

Query: 548 RELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRL 607
           RE  S +   L   G+KI   TL+VGDYI+S  + +ERKS  D  QS   GRLF QV+ +
Sbjct: 731 REFMSSLPNVLHQKGMKIIPVTLEVGDYILSPSICVERKSIQDLFQSFTSGRLFHQVEMM 790

Query: 608 KDSYPRPVVIVE---GQLYGIR-------NVHPNAIRGAIASIVIDF-GVPIIFSSNPEE 656
              Y  PV+++E    + +  +       +V P  I   ++ +V+ F  + +++S +   
Sbjct: 791 SRYYRIPVLLIEFSQDKSFSFQSSSDISDDVTPYNIISKLSLLVLHFPRLRLLWSRSLHA 850

Query: 657 TAN-YIFFMARREQEERRREVRV-------------RGEKKALTLAERQRLIVESLPHVS 702
           TA  +    + +++ +  R +RV             R E    +  E     +  LP VS
Sbjct: 851 TAEIFTTLKSNQDEPDETRAIRVGVPSEEGIIENDIRAENYNTSAVE----FLRRLPGVS 906

Query: 703 ATLAKRLLKHFGSVERVFTASVPELMKVEGIGEKIAREIRRVITSPY 749
               + +++   S+  + +  V  L ++ G G K+A+ +R  + + Y
Sbjct: 907 DANYRSIMEKCKSLAELASLPVETLAELMG-GHKVAKSLREFLDAKY 952


>dbj|BAA28847.1| (AB009461) MUS38 [Neurospora crassa]
           Length = 892
           
 Score = 81.9 bits (199), Expect = 2e-14
 Identities = 72/265 (27%), Positives = 116/265 (43%), Gaps = 29/265 (10%)

Query: 433 EEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKE 492
           E  L+  +   ++ YEP  S IR V+    +   +  RV  L   G+ +E  Y SS  +E
Sbjct: 530 EHVLEEVKPKYIIMYEPDASFIRRVEVYRSSHNDRNVRVYFLYYGGSVEEQRYLSSVRRE 589

Query: 493 RQMRETIRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEE-------RKGEREGVKVVV 545
           +      +++ +       ++ +S+  +D E    R             K   +  +VVV
Sbjct: 590 KDA--FTKLIRERASMSIVMTTDSHGVEDPESAFLRTINTRIAGGGKLAKATAQPPRVVV 647

Query: 546 DSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVK 605
           D RE RS +   L    + I    L VGDYI+S  + +ERKS +D I S  DGRL+ Q +
Sbjct: 648 DVREFRSSLPSLLHGRSMVIVPCMLTVGDYILSPNICVERKSVSDLISSFKDGRLYAQCE 707

Query: 606 RLKDSYPRPVVIVE----------------GQLYGIRNVHPNAIRGAI-ASIVIDFGVP- 647
            +   Y  P++++E                G L  +   +  A R A+  S ++    P 
Sbjct: 708 TMFQHYRNPMLLIEFDQNKSFTLEPFADLSGSLRSVNPENAGAQRLAVQKSCLLTLAFPK 767

Query: 648 --IIFSSNPEETANYIFFMARREQE 670
             II+SS+P ETA     +   E+E
Sbjct: 768 LRIIWSSSPYETAEIFERLKALEEE 792


>gb|AAF81910.1|AF277377_1 (AF277377) 5' repair endonuclease [Arabidopsis thaliana]
           Length = 956
           
 Score = 80.4 bits (195), Expect = 7e-14
 Identities = 80/347 (23%), Positives = 151/347 (43%), Gaps = 39/347 (11%)

Query: 436 LDVPEVDLVVFYEPVPSAIRSVQ-RRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQ 494
           LD+ +  +++ Y P    +R ++  +     +K     I   + T  + +  S + +   
Sbjct: 612 LDILKPSVIIVYHPDMGFVRELEVYKAENPLRKLKVYFIFYDESTEVQKFEASIRRENEA 671

Query: 495 MRETIRMVSQAIKREKQLSL-------ESYVKKDTEKEMEREEKEERKGEREGVKVVVDS 547
               IR  S  I    Q  L         +    T+  + R+    ++ E+E  +V+VD 
Sbjct: 672 FESLIRQKSSMIIPVDQDGLCMGSNSSTEFPASSTQNSLTRKAGGRKEVEKE-TQVIVDM 730

Query: 548 RELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRL 607
           RE  S +   L   G+KI   TL+VGDYI+S  + +ERKS  D  QS   GRLF QV+ +
Sbjct: 731 REFMSSLPNVLHQKGMKIIPVTLEVGDYILSPSICVERKSIQDLFQSFTSGRLFHQVEMM 790

Query: 608 KDSYPRPVVIVE---GQLYGIR-------NVHPNAIRGAIASIVIDF-GVPIIFSSNPEE 656
              Y  PV+++E    + +  +       +V P  I   ++ +V+    + +++S +   
Sbjct: 791 SRYYRIPVLLIEFSQDKSFSFQSSSDISDDVTPYNIISKLSLLVLHSPRLRLLWSRSLHA 850

Query: 657 TAN-YIFFMARREQEERRREVRV-------------RGEKKALTLAERQRLIVESLPHVS 702
           TA  +    + +++ +  R +RV             R E    +  E     +  LP VS
Sbjct: 851 TAEIFTTLKSNQDEPDETRAIRVGVPSEEGIIENDIRAENYNTSAVE----FLRRLPGVS 906

Query: 703 ATLAKRLLKHFGSVERVFTASVPELMKVEGIGEKIAREIRRVITSPY 749
               + +++   S+  + +  V  L ++ G G K+A+ +R  + + Y
Sbjct: 907 DANYRSIMEKCKSLAELASLPVETLAELMG-GHKVAKSLREFLDAKY 952


>gb|AAF45938.1| (AE003430) mei-9 gene product [Drosophila melanogaster]
           Length = 961
           
 Score = 77.3 bits (187), Expect = 6e-13
 Identities = 56/201 (27%), Positives = 104/201 (50%), Gaps = 14/201 (6%)

Query: 433 EEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPG---RVVILIAQGTRDEAYYWSSK 489
           E  L+  +   VV Y    +AIR ++      R  P    +V  LI   T +E  Y +S 
Sbjct: 574 EHMLEQLQPHYVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSL 633

Query: 490 HKERQMRETI-----RMVSQAIKREKQ----LSLESYVKKDTEKEMEREEK--EERKGER 538
            +E+   E I     +MV    +  K     L L++Y  + T++  +  +   +  +  +
Sbjct: 634 RREKAAFEFIIDTKSKMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATK 693

Query: 539 EGVKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDG 598
           E  KV+VD RE RS++   +   G+++   T+ +GDYI++ ++ +ERKS +D I S+  G
Sbjct: 694 ETPKVIVDMREFRSDLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSG 753

Query: 599 RLFDQVKRLKDSYPRPVVIVE 619
           RL++Q  +++  Y +P++++E
Sbjct: 754 RLYNQCVQMQRHYAKPILLIE 774


>sp|Q24087|MEI9_DROME MEI-9 PROTEIN (MEIOTIC-9 PROTEIN) >gi|2133695|pir||S58936 meiotic
           recombination protein mei-9 - fruit fly (Drosophila
           melanogaster) >gi|924919|gb|AAC46917.1| (U27181) MEI-9
           [Drosophila melanogaster] >gi|1585596|prf||2201389A
           mei-9 gene [Drosophila melanogaster]
           Length = 926
           
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 55/201 (27%), Positives = 103/201 (50%), Gaps = 14/201 (6%)

Query: 433 EEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPG---RVVILIAQGTRDEAYYWSSK 489
           E  L+  +   VV Y    + IR ++      R  P    +V  LI   T +E  Y +S 
Sbjct: 531 EHMLEQLQPHYVVMYNMNVTPIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSL 590

Query: 490 HKERQMRETI-----RMVSQAIKREKQ----LSLESYVKKDTEKEMEREEK--EERKGER 538
            +E+   E I     +MV    +  K     L L++Y  + T++  +  +   +  +  +
Sbjct: 591 RREKAAFEFIIDTKSKMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATK 650

Query: 539 EGVKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDG 598
           E  KV+VD RE RS++   +   G+++   T+ +GDYI++ ++ +ERKS +D I S+  G
Sbjct: 651 ETPKVIVDMREFRSDLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSG 710

Query: 599 RLFDQVKRLKDSYPRPVVIVE 619
           RL++Q  +++  Y +P++++E
Sbjct: 711 RLYNQCVQMQRHYAKPILLIE 731


>emb|CAB70217.1| (AL033535) Similarity to Yeast DNA repair protein RAD16
           (SW:RAD16_SCHPO)~cDNA EST EMBL:Z14466 comes from this
           gene~cDNA EST yk636b12.5 comes from this gene~cDNA EST
           yk86a4.3 comes from this gene~cDNA EST yk131g2.3 comes
           from this gene~cDNA EST yk86a4.5>
           >gi|6782250|emb|CAA93766.2| (Z69902) Similarity to Yeast
           DNA repair protein RAD16 (SW:RAD16_SCHPO)~cDNA EST
           EMBL:Z14466 comes from this gene~cDNA EST yk636b12.5
           comes from this gene~cDNA EST yk86a4.3 comes from this
           gene~cDNA EST yk131g2.3 comes from this gene~cDNA EST
           yk86a4.5 c>
           Length = 935
           
 Score = 74.9 bits (181), Expect = 3e-12
 Identities = 43/133 (32%), Positives = 70/133 (52%), Gaps = 18/133 (13%)

Query: 521 DTEKEMEREEKEERKGEREGVKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDE 580
           D   +M+ EE+ ER       K++VD RE  SE+   L T G  +   T+++GDYI+S  
Sbjct: 672 DPRDQMDPEEELERP------KIIVDMREFNSELPTVLYTKGYNVVATTIEIGDYILSPN 725

Query: 581 VAIERKSANDFIQSIIDGRLFDQVKRLKDSYPRPVVIVE------------GQLYGIRNV 628
           +AIERK+ +D  QS+  GR+F Q++++ + Y   V+++E            G   G  + 
Sbjct: 726 IAIERKALDDLTQSLQSGRVFKQIEQMLEHYDCTVLLIESNRKFETKIVNGGPFQGELSR 785

Query: 629 HPNAIRGAIASIV 641
           H   IR    S++
Sbjct: 786 HCREIRSIFCSLI 798


>pir||T18568 hypothetical protein VF13D12L.2 - Caenorhabditis elegans
           Length = 401
           
 Score = 74.9 bits (181), Expect = 3e-12
 Identities = 43/133 (32%), Positives = 70/133 (52%), Gaps = 18/133 (13%)

Query: 521 DTEKEMEREEKEERKGEREGVKVVVDSRELRSEVVKRLKTLGVKIEVKTLDVGDYIISDE 580
           D   +M+ EE+ ER       K++VD RE  SE+   L T G  +   T+++GDYI+S  
Sbjct: 138 DPRDQMDPEEELERP------KIIVDMREFNSELPTVLYTKGYNVVATTIEIGDYILSPN 191

Query: 581 VAIERKSANDFIQSIIDGRLFDQVKRLKDSYPRPVVIVE------------GQLYGIRNV 628
           +AIERK+ +D  QS+  GR+F Q++++ + Y   V+++E            G   G  + 
Sbjct: 192 IAIERKALDDLTQSLQSGRVFKQIEQMLEHYDCTVLLIESNRKFETKIVNGGPFQGELSR 251

Query: 629 HPNAIRGAIASIV 641
           H   IR    S++
Sbjct: 252 HCREIRSIFCSLI 264


>dbj|BAB13422.1| (AB046816) KIAA1596 protein [Homo sapiens]
            Length = 1151
            
 Score = 74.5 bits (180), Expect = 4e-12
 Identities = 57/216 (26%), Positives = 107/216 (49%), Gaps = 10/216 (4%)

Query: 537  EREGVKVVVDSRELRS--EVVKRLKTL-GVKIEVKTLDVGDYIISDEVAIERKSANDFIQ 593
            E +G  ++V   E+ S  EV+  L+ + G+++EV  L+  DYI+S+ + +ER+S ++ + 
Sbjct: 917  EGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNRMVVERRSQSEMLN 976

Query: 594  SIIDGRLFDQVKRLKDSYPRPVVIVEGQLYGI----RNVHPNAIRGAIASIVIDFGVPII 649
            S+   +  +Q++ L+  + R  VIVE          R         ++ + +I  G+ I+
Sbjct: 977  SVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRIL 1036

Query: 650  FSSNPEETANYIFFMARREQEERRREVRVRGEKKALTLAERQRLIVESLPHVSATLAKRL 709
            FSS  EETA+ +  ++  EQ   R+ V +       +          S+P++S   A  +
Sbjct: 1037 FSSCQEETADLLKELSLVEQ---RKNVGIHVPTVVNSNKSEALQFYLSIPNISYITALNM 1093

Query: 710  LKHFGSVERVFTASVPELMKVEGIGEKIAREIRRVI 745
               F SV+R+  +S+ E+     +  + A EI R I
Sbjct: 1094 CHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYI 1129


>dbj|BAA31233.1| (D89592) rhlE [Vibrio alginolyticus]
           Length = 411
           
 Score = 71.8 bits (173), Expect = 3e-11
 Identities = 48/192 (25%), Positives = 93/192 (48%), Gaps = 11/192 (5%)

Query: 349 EVLKELVKEQLSKKENSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQ 408
           ++   L+   L++ + S++++F   +  A K+V +L K GI A+ F          G +Q
Sbjct: 228 DMKSSLLSHMLNENDWSQVLIFIETKHGAAKLVSQLEKRGIVAEAF--------HSGRNQ 279

Query: 409 REQKLILDSFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQ-K 467
           R ++ +++ F  GE   LVAT V   G+D+  + +V+ Y+    A   V R GRTGR   
Sbjct: 280 RVRQELIEKFKAGEIQYLVATGVAARGIDIDNLPVVINYDLPFPADEYVHRIGRTGRAGA 339

Query: 468 PGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKKDTEKEME 527
            G  + L+++   D       + +   + E + +   A ++   +S+ +YV K+  K  +
Sbjct: 340 QGEAISLVSKD--DFKNLCMIESRLGHLLERVEIEGFAPRKPVPISILNYVPKNKRKPQD 397

Query: 528 REEKEERKGERE 539
              + E   +R+
Sbjct: 398 NRPRRENSEQRD 409


>pir||B72707 hypothetical protein APE1073 - Aeropyrum pernix (strain K1)
           >gi|5104743|dbj|BAA80058.1| (AP000060) 539aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 539
           
 Score = 71.8 bits (173), Expect = 3e-11
 Identities = 53/181 (29%), Positives = 91/181 (49%), Gaps = 27/181 (14%)

Query: 305 KKLYEEAKTGSTRASKELFLDRRMKKALALLIQAKELGIDHPKMEVLKELVKEQLSKKEN 364
           +K+ E+A+ G   A + + ++ RMK+ + L            K+  +++LV+E+LS+   
Sbjct: 373 EKILEDARRGDPTAIEAIRVNTRMKEIVQL---------SESKIRAVEKLVREELSR--G 421

Query: 365 SKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATKENDRGMSQREQKLILDSFARGEFN 424
           SK+IVFT YR  A ++            R  G        G+ +R ++  L  F   +  
Sbjct: 422 SKVIVFTQYRRQAEEIA-----------RRTGALLLHG--GLERRVREATLAKFRALKAG 468

Query: 425 VLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRRGRTGRQKPGRVVIL---IAQGTRD 481
            LV T+VG+EGLD+P+ ++ +      S  + +QR GR  R   G+  +L   IA+GT +
Sbjct: 469 ALVVTTVGDEGLDIPDANVGILVSGTGSRRQFIQRLGRLLRPGEGKRAVLYEVIARGTGE 528

Query: 482 E 482
           E
Sbjct: 529 E 529


>sp|P42305|DEAD_BACSU COLD-SHOCK DEAD-BOX PROTEIN A HOMOLOG (ATP-DEPENDENT RNA HELICASE
           DEAD HOMOLOG) >gi|7446092|pir||E69613 ATP-dependent RNA
           helicase deaD - Bacillus subtilis
           >gi|665989|dbj|BAA11693.1| (D83026) homologous to ATP
           dependent RNA helicase DeaD of E. coli; hypothetical
           [Bacillus subtilis] >gi|2636457|emb|CAB15947.1| (Z99124)
           ATP-dependent RNA helicase [Bacillus subtilis]
           Length = 479
           
 Score = 71.4 bits (172), Expect = 3e-11
 Identities = 86/396 (21%), Positives = 166/396 (41%), Gaps = 46/396 (11%)

Query: 234 KPLAEAGLIESASADLPKKEILRAGQIINEETAKGNHDLRK--LLLFHAMALKLHHAIEL 291
           K +    +   +S D  K E+ +   I+     +    + K  L L     L +  A E+
Sbjct: 97  KRIKATAVFGKSSFDKQKAELKQKSHIVVGTPGRVLDHIEKGTLPLDRLSYLVIDEADEM 156

Query: 292 LETQGLSALRVYLKKLYEEAKTGSTRASKELFLDRRMKKALALL--IQAKELG-----ID 344
           L    +  +   +K L  E  T    A+    +++  ++ +     I+ K  G     I+
Sbjct: 157 LNMGFIEQVEAIIKHLPTERTTMLFSATLPQDIEKLSRQYMQNPEHIEVKAAGLTTRNIE 216

Query: 345 HPKMEVLKE----LVKEQLSKKENSKIIVFTNYRETARKVVEELTKEGIKAKRFVGQATK 400
           H  ++V +E    L+K+ L  +     I+F   +E   ++ +EL   G    +  G    
Sbjct: 217 HAVIQVREENKFSLLKDVLMTENPDSCIIFCRTKEHVNQLTDELDDLGYPCDKIHG---- 272

Query: 401 ENDRGMSQREQKLILDSFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSVQRR 460
               GM Q ++  +++ F RGE+  LVAT V   G+D+  + LV+ Y+        V R 
Sbjct: 273 ----GMIQEDRFDVMNEFKRGEYRYLVATDVAARGIDIENISLVINYDLPLEKESYVHRT 328

Query: 461 GRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQMRETIRMVSQAIKREKQLSLESYVKK 520
           GRTGR            G + +A  + +  ++R + +    +   I + +  S E   +K
Sbjct: 329 GRTGR-----------AGNKGKAISFVTAFEKRFLADIEEYIGFEIPKIEAPSQEEVARK 377

Query: 521 DTEKEMEREEKEERKGEREGVKVVVDSRELRSEVVKRLKTLGVKIEVKTLD-VG-----D 574
             E   +  ++ E K ++        S EL  +++K     G K +++ +D VG     D
Sbjct: 378 KPEFLAKLNDRPESKKDK--------SEELNKDIMKLYFNGGKKKKIRAVDFVGTIAKID 429

Query: 575 YIISDEVAIERKSANDFIQSIIDGRLFDQVKRLKDS 610
            + +D++ I     N     I++G+    +K +K++
Sbjct: 430 GVSADDIGIITIMDNASYVEILNGKGPHVLKVMKNT 465


>gi|6325235 UV endonuclease; Rad1p [Saccharomyces cerevisiae]
            >gi|131810|sp|P06777|RAD1_YEAST DNA REPAIR PROTEIN RAD1
            >gi|73262|pir||DDBYD1 RAD1 protein - yeast (Saccharomyces
            cerevisiae) >gi|172325|gb|AAA34934.1| (M15435) RAD1
            protein [Saccharomyces cerevisiae]
            >gi|1039455|gb|AAB68165.1| (U36624) Rad1p [Saccharomyces
            cerevisiae]
            Length = 1100
            
 Score = 70.2 bits (169), Expect = 7e-11
 Identities = 74/345 (21%), Positives = 150/345 (43%), Gaps = 51/345 (14%)

Query: 444  VVFYEPVPSAIRSVQRRGRTGRQKPGRVVILIAQGTRDEAYYWSSKHKERQ-----MRET 498
            ++ +EP  S IR ++      +    +V  +    + +E  + ++  +E+      +RE 
Sbjct: 712  IIMFEPDISFIRQIEVYKAIVKDLQPKVYFMYYGESIEEQSHLTAIKREKDAFTKLIREN 771

Query: 499  IRMVSQAIKREKQLSLESYVKKDTEKEMEREEKEERKGEREGVK------VVVDSRELRS 552
              +       E     ++  ++  +    R+      G ++G        V+VD+RE  +
Sbjct: 772  ANLSHHFETNEDLSHYKNLAERKLKLSKLRKSNTRNAGGQQGFHNLTQDVVIVDTREFNA 831

Query: 553  EVVKRLKTLGVKIEVKTLDVGDYIISDEVAIERKSANDFIQSIIDGRLFDQVKRLKDSYP 612
             +   L   G+++    L VGDY+I+ ++ +ERKS +D I S+ + RL +Q K++   Y 
Sbjct: 832  SLPGLLYRYGIRVIPCMLTVGDYVITPDICLERKSISDLIGSLQNNRLANQCKKMLKYYA 891

Query: 613  RPVVIV---EGQLYG--------------IRNVHP-------NAIRGAIASIVIDF-GVP 647
             P +++   EGQ +               I  VHP       + I+  +A +V+ F  + 
Sbjct: 892  YPTLLIEFDEGQSFSLEPFSERRNYKNKDISTVHPISSKLSQDEIQLKLAKLVLRFPTLK 951

Query: 648  IIFSSNPEETANYIF-FMARREQEERRREV-------------RVRGEKKALTLAERQRL 693
            II+SS+P +T N I      REQ +    V               +G K     ++ +RL
Sbjct: 952  IIWSSSPLQTVNIILELKLGREQPDPSNAVILGTNKVRSDFNSTAKGLKDGDNESKFKRL 1011

Query: 694  I-VESLPHVSATLAKRLLKHFGSVERVFTASVPELMKVEGIGEKI 737
            + V  +  +     ++ +K F  ++++    + EL+  E + ++I
Sbjct: 1012 LNVPGVSKIDYFNLRKKIKSFNKLQKLSWNEINELINDEDLTDRI 1056


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.318    0.136    0.370 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 253501257
Number of Sequences: 2977
Number of extensions: 10571981
Number of successful extensions: 61815
Number of sequences better than 1.0e-10: 45
Number of HSP's better than  0.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 61656
Number of HSP's gapped (non-prelim): 67
length of query: 752
length of database: 189,106,746
effective HSP length: 63
effective length of query: 689
effective length of database: 151,402,065
effective search space: 104316022785
effective search space used: 104316022785
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 168 (69.9 bits)