BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0214 (soxB) DE:sarcosine oxidase, subunit beta (soxB)
         (379 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||F75144 sarcosine oxidase, chain beta (soxb) PAB0214 - Pyroc...   791  0.0
pir||B71184 probable sarcosine oxidase - Pyrococcus horikoshii >...   705  0.0
pir||F71008 probable sarcosine oxidase - Pyrococcus horikoshii >...   420  e-116
pir||G75122 sarcosine oxidase, chain beta (soxb) PAB1843 - Pyroc...   414  e-114
gi|11497890 sarcosine oxidase, subunit beta (soxB) [Archaeoglobu...   190  3e-47
sp|Q63342|M2GD_RAT DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL ...   158  1e-37
gi|11417071 dimethylglycine dehydrogenase precursor [Homo sapiens]    155  8e-37
gi|7019365 dimethylglycine dehydrogenase precursor [Homo sapiens...   155  8e-37
gb|AAD03414.1| (AF067650) sarcosine dehydrogenase [Rattus norveg...   129  4e-29
gb|AAD32214.1| (AF140745) sarcosine dehydrogenase [Homo sapiens]...   129  4e-29
gb|AAD53398.2|AF095735_1 (AF095735) sarcosine dehydrogenase [Hom...   129  4e-29
gb|AAD13137.1| (AF047190) dimethylglycine dehydrogenase-like pro...   129  6e-29
gi|8923708 hypothetical protein [Homo sapiens] >gi|11437505|ref|...   124  1e-27
sp|P40875|SAOX_CORS1 SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE O...   123  3e-27
gb|AAC48785.1| (AF026954) pyruvate dehydrogenase phosphatase reg...   118  8e-26
gb|AAK40533.1| Sarcosine oxidase, subunit beta (soxB-like) [Sulf...   118  1e-25
gb|AAD13136.1| (AF047004) dimethylglycine dehydrogenase-like pro...   115  9e-25
gb|AAF57379.1| (AE003789) CG3270 gene product [Drosophila melano...   112  6e-24
gb|AAF57796.1| (AE003802) CG6385 gene product [Drosophila melano...   111  1e-23
pir||E72254 conserved hypothetical protein - Thermotoga maritima...   108  1e-22
gi|10955084 agaE [Agrobacterium tumefaciens] >gi|11352852|pir||T...   106  6e-22
pir||H82968 sarcosine oxidase beta subunit PA5416 [imported] - P...   105  8e-22
dbj|BAB05153.1| (AP001512) glycine oxidase (sarcosine oxidase) [...   103  3e-21
sp|O31616|GLOX_BACSU GLYCINE OXIDASE >gi|7475812|pir||B69845 sar...   102  7e-21
gb|AAD53399.2|AF095736_1 (AF095736) unknown [Homo sapiens]            102  7e-21
gi|6005868 sarcosine dehydrogenase; dimethylglycine dehydrogenas...   101  1e-20
gb|AAB03674.1| (U62481) dimethylglycine dehydrogenase-like prote...    96  7e-19
dbj|BAB05760.1| (AP001514) unknown conserved protein [Bacillus h...    93  4e-18
sp|O87388|SAOX_RHIME SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE O...    92  8e-18
pir||F83487 hypothetical protein PA1267 [imported] - Pseudomonas...    92  1e-17
pir||H83370 hydrogen cyanide synthase HcnC PA2195 [imported] - P...    91  2e-17
gb|AAK42656.1| Glycerol-3-phosphate dehydrogenase chain A (glpA)...    90  5e-17
sp|Q52671|SAOX_RHOCA SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE O...    87  4e-16
pir||E82983 probable oxidoreductase PA5309 [imported] - Pseudomo...    83  7e-15
gb|AAC38596.1| (AF053760) hydrogen cyanide synthase HcnC [Pseudo...    83  7e-15
pir||H70361 conserved hypothetical protein aq_707 - Aquifex aeol...    82  1e-14
pir||C83407 hypothetical protein PA1918 [imported] - Pseudomonas...    80  3e-14
pir||G83298 conserved hypothetical protein PA2776 [imported] - P...    79  7e-14
gb|AAG20146.1| (AE005092) glycerol-3-phosphate dehydrogenase cha...    79  7e-14
pir||S76505 hypothetical protein - Synechocystis sp. (strain PCC...    79  1e-13
gb|AAA96395.1| (U38892) N-terminal and C-terminal ends are simil...    79  1e-13
sp|P44732|ORDL_HAEIN PROBABLE OXIDOREDUCTASE ORDL >gi|1073832|pi...    77  4e-13
sp|O32159|YURR_BACSU HYPOTHETICAL 39.4 KD OXIDOREDUCTASE IN HOM-...    76  6e-13
pir||B75218 glycerol-3-phosphate dehydrogenase (glpa) PAB0183 - ...    75  1e-12
sp|P37906|ORDL_ECOLI PROBABLE OXIDOREDUCTASE ORDL >gi|7449558|pi...    74  2e-12
dbj|BAB09014.1| (AB007645) contains similarity to unknown protei...    73  4e-12
emb|CAC11772.1| (AL445064) glycerol-3-phosphate dehydrogenase re...    71  2e-11
pir||G81179 oxidoreductase, probable NMB0614 [imported] - Neisse...    71  2e-11
pir||B83078 probable D-amino acid oxidase PA4548 [imported] - Ps...    71  2e-11
pir||T35488 probable oxidoreductase - Streptomyces coelicolor (f...    70  4e-11
sp|P43799|GLPA_HAEIN ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENAS...    69  6e-11

>pir||F75144 sarcosine oxidase, chain beta (soxb) PAB0214 - Pyrococcus abyssi
           (strain Orsay) >gi|5457747|emb|CAB49237.1| (AJ248284)
           sarcosine oxidase, subunit beta (soxB) [Pyrococcus
           abyssi]
           Length = 379
           
 Score =  791 bits (2020), Expect = 0.0
 Identities = 379/379 (100%), Positives = 379/379 (100%)

Query: 1   MIGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY 60
           MIGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY
Sbjct: 1   MIGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY 60

Query: 61  SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKE 120
           SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKE
Sbjct: 61  SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKE 120

Query: 121 IVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK 180
           IVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK
Sbjct: 121 IVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK 180

Query: 181 IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240
           IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP
Sbjct: 181 IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240

Query: 241 AWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQ 300
           AWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQ
Sbjct: 241 AWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQ 300

Query: 301 WAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEW 360
           WAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEW
Sbjct: 301 WAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEW 360

Query: 361 YDPYRFERGELRTSAFQIG 379
           YDPYRFERGELRTSAFQIG
Sbjct: 361 YDPYRFERGELRTSAFQIG 379


>pir||B71184 probable sarcosine oxidase - Pyrococcus horikoshii
           >gi|3258182|dbj|BAA30865.1| (AP000007) 377aa long
           hypothetical sarcosine oxidase [Pyrococcus horikoshii]
           Length = 377
           
 Score =  705 bits (1801), Expect = 0.0
 Identities = 329/379 (86%), Positives = 361/379 (94%), Gaps = 2/379 (0%)

Query: 1   MIGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY 60
           MIG+IGGGIIG+ATAYELAKLGEEV+VFEKRYFGSGSTFRCASGIRAQFTDEANI+LMKY
Sbjct: 1   MIGIIGGGIIGIATAYELAKLGEEVIVFEKRYFGSGSTFRCASGIRAQFTDEANIRLMKY 60

Query: 61  SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKE 120
           SI++WK+LSEEL + +MFQQTGYLFLAT+EEEV+AFK+NIKLQN+FGVPTKLITPEEAKE
Sbjct: 61  SIDKWKKLSEELEYEVMFQQTGYLFLATSEEEVKAFKRNIKLQNKFGVPTKLITPEEAKE 120

Query: 121 IVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK 180
           IVPPLN + FLAGAWNPEDGKASPFHTLY YK+AGEKLGV+FYPYTEV+ I   +  KW 
Sbjct: 121 IVPPLNADAFLAGAWNPEDGKASPFHTLYGYKRAGEKLGVRFYPYTEVIGIK--KNDKWI 178

Query: 181 IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240
           IKTT+GEF VDVIVNATNAWG RINSMIGKDIVPI PFKHQLVKTEP+ERGQIEPLVCPP
Sbjct: 179 IKTTRGEFRVDVIVNATNAWGRRINSMIGKDIVPIKPFKHQLVKTEPIERGQIEPLVCPP 238

Query: 241 AWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQ 300
           AW+DSYVIQDGEDGGVICGTALEYK +PDDVTPTYDFVKE LKWAVKI+PAL+HVH++RQ
Sbjct: 239 AWSDSYVIQDGEDGGVICGTALEYKGNPDDVTPTYDFVKEALKWAVKIVPALKHVHIIRQ 298

Query: 301 WAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEW 360
           WAG+YAKTPDNNPAIGEL EDFYVAIGFSGHGFMMAPAV+QALAE+IVKG+TKVPLDWEW
Sbjct: 299 WAGYYAKTPDNNPAIGELEEDFYVAIGFSGHGFMMAPAVSQALAEKIVKGKTKVPLDWEW 358

Query: 361 YDPYRFERGELRTSAFQIG 379
           +DPYRFERGELR+SAFQIG
Sbjct: 359 FDPYRFERGELRSSAFQIG 377


>pir||F71008 probable sarcosine oxidase - Pyrococcus horikoshii
           >gi|3257787|dbj|BAA30470.1| (AP000006) 382aa long
           hypothetical sarcosine oxidase [Pyrococcus horikoshii]
           Length = 382
           
 Score =  420 bits (1067), Expect = e-116
 Identities = 213/382 (55%), Positives = 277/382 (71%), Gaps = 11/382 (2%)

Query: 2   IGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61
           I VIGGGI+GV  A+ELAK GEEV V EKR+ GSGSTFRC +GIR QF DEAN+++MK S
Sbjct: 8   IVVIGGGIVGVTIAHELAKRGEEVTVIEKRFIGSGSTFRCGTGIRQQFNDEANVRVMKRS 67

Query: 62  IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           +E WK+ SEE G +  F+QTGYLFL   +EEV+ FK+NI++QN+FGVPTKLITPEEAKEI
Sbjct: 68  VELWKKYSEEYGFS--FKQTGYLFLLYDDEEVKTFKRNIEIQNKFGVPTKLITPEEAKEI 125

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181
           VP L++ E +A +WNP DGKA PF    A+    ++ G K   YTEV            +
Sbjct: 126 VPLLDISEVIAASWNPTDGKADPFEATTAFAVKAKEYGAKLLEYTEVKGFLIENNEIKGV 185

Query: 182 KTTKGEFEVDVIVNATNAWGSRINSMIG-KDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240
           KT KG  +  ++VNATNAW + IN+M G K  +PI P+KHQ V T+P++RG I P+V   
Sbjct: 186 KTNKGIIKTGIVVNATNAWANLINAMAGIKTKIPIEPYKHQAVITQPIKRGTINPMVISF 245

Query: 241 AWNDSYVIQDGEDGGVICGTALEYKSDPD-DVTPTYDFVKEVLKWAVKIIPALRHVHVVR 299
            +  +Y+ Q    GG+I G  + Y+  P  D+TPTY+F++EV  +  KIIPAL+++ ++R
Sbjct: 246 KYGHAYLTQTFH-GGIIGG--IGYEIGPTYDLTPTYEFLREVSYYFTKIIPALKNLLILR 302

Query: 300 QWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLD 357
            WAG+YAKTPD+NPAIG + E  D+Y+A GFSGHGFMMAPAV + +AE I KG+TK+P+ 
Sbjct: 303 TWAGYYAKTPDSNPAIGRIEELNDYYIAAGFSGHGFMMAPAVGEMVAELITKGKTKLPV- 361

Query: 358 WEWYDPYRFERGELRTSAFQIG 379
            EWYDPYRFERGELRT+A Q+G
Sbjct: 362 -EWYDPYRFERGELRTAALQMG 382


>pir||G75122 sarcosine oxidase, chain beta (soxb) PAB1843 - Pyrococcus abyssi
           (strain Orsay) >gi|5458207|emb|CAB49696.1| (AJ248285)
           sarcosine oxidase, subunit beta (soxB) [Pyrococcus
           abyssi]
           Length = 382
           
 Score =  414 bits (1052), Expect = e-114
 Identities = 209/380 (55%), Positives = 275/380 (72%), Gaps = 11/380 (2%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63
           VIGGGI+GV+ A+ELAK G +V V EKR+ GSGSTFRC +GIR QF DEAN+++MK S+E
Sbjct: 10  VIGGGIVGVSIAHELAKRGVDVTVLEKRFIGSGSTFRCGTGIRQQFNDEANVRVMKRSVE 69

Query: 64  RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVP 123
            WK+ SEE  +N  F+QTGYLFL   EEEVE FK+NI++QN+FGVPT+LITPEEAKEIVP
Sbjct: 70  LWKKYSEE--YNFSFKQTGYLFLLYDEEEVETFKRNIEIQNKFGVPTRLITPEEAKEIVP 127

Query: 124 PLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKIKT 183
            L++ E +A +WNP DGKA PF    A+     + G K   YTEV            +KT
Sbjct: 128 LLDISEVIAASWNPTDGKADPFEATTAFAIKAREYGAKLLEYTEVKGFIIENGEIKGVKT 187

Query: 184 TKGEFEVDVIVNATNAWGSRINSMIG-KDIVPITPFKHQLVKTEPLERGQIEPLVCPPAW 242
            +G  +  ++VNATNAW   IN+M G K  +PI P+KHQ V T+P++RG I P+V    +
Sbjct: 188 NRGTIKTGIVVNATNAWAKLINAMAGIKVKIPIEPYKHQAVITQPIKRGTINPMVISFKY 247

Query: 243 NDSYVIQDGEDGGVICGTALEYKSDPD-DVTPTYDFVKEVLKWAVKIIPALRHVHVVRQW 301
             +Y+ Q    GG+I G  + Y+  P  D+TPTY+F++EV  +  KIIPAL+++ V+R W
Sbjct: 248 GHAYLTQTFH-GGIIGG--IGYEIGPTYDLTPTYEFLREVSYYFTKIIPALKNLLVLRTW 304

Query: 302 AGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWE 359
           AG+YAKTPD+NPAIG++ E  D+Y+A GFSGHGFMMAPAV + +A+ I KG++K+P+  E
Sbjct: 305 AGYYAKTPDSNPAIGKIEELSDYYIAAGFSGHGFMMAPAVGEMIADLITKGKSKLPV--E 362

Query: 360 WYDPYRFERGELRTSAFQIG 379
           WYDPYRFERGELRT+A Q+G
Sbjct: 363 WYDPYRFERGELRTAALQMG 382


>gi|11497890 sarcosine oxidase, subunit beta (soxB) [Archaeoglobus fulgidus]
           >gi|7483942|pir||B69284 sarcosine oxidase, subunit beta
           (soxB) homolog - Archaeoglobus fulgidus
           >gi|2650362|gb|AAB90958.1| (AE001086) sarcosine oxidase,
           subunit beta (soxB) [Archaeoglobus fulgidus]
           Length = 354
           
 Score =  190 bits (477), Expect = 3e-47
 Identities = 117/356 (32%), Positives = 192/356 (53%), Gaps = 13/356 (3%)

Query: 2   IGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61
           + VIGGG+ G++ AY LAK G +V VFE++Y   G++ R + G+ AQFT+EA IKL K +
Sbjct: 3   VAVIGGGVAGLSAAYFLAKAGADVKVFEQKYLLYGASGRNSGGLTAQFTNEAMIKLAKRT 62

Query: 62  IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           +E + EL  E+G N + ++ GY+ +A   EE +  ++ ++ Q + GV  K++ PE  KE+
Sbjct: 63  LELYDELQSEVGFNFLLRRDGYVKIAGKGEEAK-LREEVEFQRKAGVKVKMVEPEFVKEL 121

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEV-VWIDGGREHKWK 180
            P +N   F A ++  + G   P+  ++   K   +LGV+ Y YT   V + G   +   
Sbjct: 122 FPDINTSAFTAASYFADGGVVFPWPVVWGLAKGCRELGVEIYDYTPASVEVKG---NDLT 178

Query: 181 IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240
           +K +   ++VD I+NA  AW + I+   G ++     F+ ++  TE L     +P + P 
Sbjct: 179 VKASGESYKVDYIINAAGAWSNEISQQAGVEL-NNKVFREEICVTESL-----KPYLDPY 232

Query: 241 AWNDSYVIQDGED-GGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVR 299
             + S  +   +   G I G  L  ++D  +   + DF+    K   +++P LR + V+R
Sbjct: 233 IMDISTGVYFSQSMRGEIVGGILGSETDRLETKASLDFLTTYAKRVTELVPKLRGMAVLR 292

Query: 300 QWAGHYAKTPDNNPAIGEL-VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKV 354
           QWAG Y    +  P IG+  V  F    GF  HG  +A A  + +AE IVKGR+ +
Sbjct: 293 QWAGLYDAGRNGMPVIGQTKVRGFIQLNGFGRHGMSLALAAGEGVAELIVKGRSSI 348


>sp|Q63342|M2GD_RAT DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR (ME2GLYDH)
           >gi|111583|pir||S16133 dimethylglycine dehydrogenase (EC
           1.5.99.2) - rat >gi|56689|emb|CAA39468.1| (X55995)
           dimethylglycine dehydrogenase [Rattus norvegicus]
           Length = 857
           
 Score =  158 bits (395), Expect = 1e-37
 Identities = 122/391 (31%), Positives = 186/391 (47%), Gaps = 40/391 (10%)

Query: 4   VIGGGIIGVATAYELAKLG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY-S 61
           +IGGG +GV+ AY LAK G  +VV+ EK    +GST+  A+G+   F    N+K + Y S
Sbjct: 47  IIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH-AAGLTTYFHPGINLKKIHYDS 105

Query: 62  IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           I+ ++ L EE G  + F Q G + LATT E V+ FK  +   N       +I PE+  E+
Sbjct: 106 IKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHEL 165

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181
            P LN+++ LAG +NP DG   P+    A      K GV       V  +    +  W +
Sbjct: 166 FPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDV 225

Query: 182 KTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTE--PLERGQIEPLVCP 239
           +T +G    + IVNA   W   +  MIG D  P+ P +HQ V T   P  +     L   
Sbjct: 226 ETPQGSVRANRIVNAAGFWAREVGKMIGLD-HPLIPVQHQYVVTSTIPEVKALKRELPVL 284

Query: 240 PAWNDSYVIQDGEDG---------------------GVICGTALE-YKSDPDDVTPTYDF 277
                SY ++   DG                     GV  G   E ++SD D +T     
Sbjct: 285 RDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRIT----- 339

Query: 278 VKEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIG--ELVEDFYVAIGFSGHGFMM 335
             E ++ A++++P L+   ++    G    +PD  P +G  + V +++VAIGF G+G + 
Sbjct: 340 --EHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYGIIH 396

Query: 336 APAVAQALAERIVKGRTKVPLDWEWYDPYRF 366
           A  V + L++ I+ G  + P D    DP R+
Sbjct: 397 AGGVGKYLSDWILHG--EPPFDLIELDPNRY 425


>gi|11417071 dimethylglycine dehydrogenase precursor [Homo sapiens]
           Length = 866
           
 Score =  155 bits (388), Expect = 8e-37
 Identities = 116/384 (30%), Positives = 183/384 (47%), Gaps = 26/384 (6%)

Query: 4   VIGGGIIGVATAYELAKLG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY-S 61
           +IGGG +GV+ AY LAK G ++VV+ EK    +GST+  A+G+   F    N+K + Y S
Sbjct: 54  IIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH-AAGLTTYFHPGINLKKIHYDS 112

Query: 62  IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           I+ +++L EE G  + F Q G + LATT   V+ FK  +           LI PE+ +E+
Sbjct: 113 IKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEM 172

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181
            P LN+ + LAG +NP DG   P+    A      K G        V  +    +  W +
Sbjct: 173 FPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDV 232

Query: 182 KTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPPA 241
           +T +G    + IVNA   W   +  MIG +  P+ P +HQ V T  +   +      P  
Sbjct: 233 ETPQGSMRANRIVNAAGFWAREVGKMIGLE-HPLIPVQHQYVVTSTISEVKALKRELPVL 291

Query: 242 --WNDSYVIQDGEDGGVICGTALEYKSDPDD------VTPTY---------DFVKEVLKW 284
                SY ++   DG +      + K    D      V P +         D + E +K 
Sbjct: 292 RDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKA 351

Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIG--ELVEDFYVAIGFSGHGFMMAPAVAQA 342
           A++++P L+   ++    G    +PD  P +G  + V +++VAIGF G+G + A  V + 
Sbjct: 352 AMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKY 410

Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366
           L++ I+ G  + P D    DP R+
Sbjct: 411 LSDWILHG--EPPFDLIELDPNRY 432


>gi|7019365 dimethylglycine dehydrogenase precursor [Homo sapiens]
           >gi|11133608|sp|Q9UI17|M2GD_HUMAN DIMETHYLGLYCINE
           DEHYDROGENASE, MITOCHONDRIAL PRECURSOR (ME2GLYDH)
           >gi|6650622|gb|AAF21941.1|AF111858_1 (AF111858)
           dimethylglycine dehydrogenase precursor [Homo sapiens]
           Length = 866
           
 Score =  155 bits (388), Expect = 8e-37
 Identities = 116/384 (30%), Positives = 183/384 (47%), Gaps = 26/384 (6%)

Query: 4   VIGGGIIGVATAYELAKLG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY-S 61
           +IGGG +GV+ AY LAK G ++VV+ EK    +GST+  A+G+   F    N+K + Y S
Sbjct: 54  IIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH-AAGLTTYFHPGINLKKIHYDS 112

Query: 62  IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           I+ +++L EE G  + F Q G + LATT   V+ FK  +           LI PE+ +E+
Sbjct: 113 IKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEM 172

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181
            P LN+ + LAG +NP DG   P+    A      K G        V  +    +  W +
Sbjct: 173 FPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDV 232

Query: 182 KTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPPA 241
           +T +G    + IVNA   W   +  MIG +  P+ P +HQ V T  +   +      P  
Sbjct: 233 ETPQGSMRANRIVNAAGFWAREVGKMIGLE-HPLIPVQHQYVVTSTISEVKALKRELPVL 291

Query: 242 --WNDSYVIQDGEDGGVICGTALEYKSDPDD------VTPTY---------DFVKEVLKW 284
                SY ++   DG +      + K    D      V P +         D + E +K 
Sbjct: 292 RDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKA 351

Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIG--ELVEDFYVAIGFSGHGFMMAPAVAQA 342
           A++++P L+   ++    G    +PD  P +G  + V +++VAIGF G+G + A  V + 
Sbjct: 352 AMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKY 410

Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366
           L++ I+ G  + P D    DP R+
Sbjct: 411 LSDWILHG--EPPFDLIELDPNRY 432


>gb|AAD03414.1| (AF067650) sarcosine dehydrogenase [Rattus norvegicus]
           Length = 919
           
 Score =  129 bits (322), Expect = 4e-29
 Identities = 106/384 (27%), Positives = 173/384 (44%), Gaps = 30/384 (7%)

Query: 4   VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           VIGGG +G  T Y LAKLG   VV+ E+    SG+T+  A  +      +  ++L+ ++ 
Sbjct: 72  VIGGGSLGCQTLYHLAKLGVGGVVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 131

Query: 63  ERWK-ELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           +    +L EE G +  + Q G LF+A+ ++ ++ +K+ + L   +G+ + +++P E K++
Sbjct: 132 QVVSHDLEEETGLHTGWIQNGGLFIASNQQRLDEYKRLMSLGKAYGIESHVLSPAETKDL 191

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI-----DGGRE 176
            P +NV++     + P DG   P  T     +A    G +      V  I     D G  
Sbjct: 192 YPLMNVDDLYGTLYVPRDGTMDPAGTCTTLTRAAVARGAQVIENCAVTGIRVRTDDFGVR 251

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
               ++T  G  +   +VN    W S +  M G   VP+    H  V TE +E  Q  P 
Sbjct: 252 RVTAVETQHGSIQTPCVVNCAGVWASSVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 310

Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284
           V     +D+ V    +   +  G    Y+++P   D+V+  + F    L W         
Sbjct: 311 VRD---HDASVYLRLQGDALSVG---GYEANPIFWDEVSDKFAFGLFDLDWDVFTQHIEG 364

Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQA 342
           A+  +P L    +     G  + TPD+ P +GE  E   F++  GF+  G M+     Q 
Sbjct: 365 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQE 424

Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366
           LA  IV GR +   D   YD  RF
Sbjct: 425 LAHWIVHGRPE--KDMYSYDIRRF 446


>gb|AAD32214.1| (AF140745) sarcosine dehydrogenase [Homo sapiens]
           >gi|5453465|gb|AAD43585.1|AF162428_1 (AF162428)
           sarcosine dehydrogenase [Homo sapiens]
           Length = 918
           
 Score =  129 bits (322), Expect = 4e-29
 Identities = 107/384 (27%), Positives = 174/384 (44%), Gaps = 30/384 (7%)

Query: 4   VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           VIGGG +G  T Y LAKLG    V+ E+    SG+T+  A  +      +  ++L+ ++ 
Sbjct: 71  VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130

Query: 63  ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
               +EL EE G +  + Q G LF+A+  + ++ +K+ + L   +GV + +++P E K +
Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176
            P +NV++     + P DG   P  T     +A    G   ++  P T + VW D  G  
Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
               ++T  G  +   +VN    W S +  M G   VP+    H  V TE +E  Q  P 
Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 309

Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284
           V     +D+ V    +   +  G    Y+++P   ++V+  + F    L W         
Sbjct: 310 VRD---HDASVYLRLQGDALSVG---GYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEG 363

Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQA 342
           A+  +P L    +     G  + TPD+ P +GE  E   F++  GF+  G M+     Q 
Sbjct: 364 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQE 423

Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366
           LA  I+ GR +   D   YD  RF
Sbjct: 424 LAHWIIHGRPE--KDMHGYDIRRF 445


>gb|AAD53398.2|AF095735_1 (AF095735) sarcosine dehydrogenase [Homo sapiens]
           Length = 918
           
 Score =  129 bits (322), Expect = 4e-29
 Identities = 107/384 (27%), Positives = 174/384 (44%), Gaps = 30/384 (7%)

Query: 4   VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           VIGGG +G  T Y LAKLG    V+ E+    SG+T+  A  +      +  ++L+ ++ 
Sbjct: 71  VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130

Query: 63  ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
               +EL EE G +  + Q G LF+A+  + ++ +K+ + L   +GV + +++P E K +
Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176
            P +NV++     + P DG   P  T     +A    G   ++  P T + VW D  G  
Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
               ++T  G  +   +VN    W S +  M G   VP+    H  V TE +E  Q  P 
Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 309

Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284
           V     +D+ V    +   +  G    Y+++P   ++V+  + F    L W         
Sbjct: 310 VRD---HDASVYLRLQGDALSVG---GYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEG 363

Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQA 342
           A+  +P L    +     G  + TPD+ P +GE  E   F++  GF+  G M+     Q 
Sbjct: 364 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQE 423

Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366
           LA  I+ GR +   D   YD  RF
Sbjct: 424 LAHWIIHGRPE--KDMHGYDIRRF 445


>gb|AAD13137.1| (AF047190) dimethylglycine dehydrogenase-like protein isoform 2;
           putative sarcosine dehydrogenase [Homo sapiens]
           >gi|4454259|emb|CAA11257.1| (AJ223317) sarcosine
           dehydrogenase [Homo sapiens]
           Length = 475
           
 Score =  129 bits (321), Expect = 6e-29
 Identities = 107/384 (27%), Positives = 174/384 (44%), Gaps = 30/384 (7%)

Query: 4   VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           VIGGG +G  T Y LAKLG    V+ E+    SG+T+  A  +      +  ++L+ ++ 
Sbjct: 71  VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130

Query: 63  ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
               +EL EE G +  + Q G LF+A+  + ++ +K+ + L   +GV + +++P E K +
Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176
            P +NV++     + P DG   P  T     +A    G   ++  P T + VW D  G  
Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
               ++T  G  +   +VN    W S +  M G   VP+    H  V TE +E  Q  P 
Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 309

Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284
           V     +D+ V    +   +  G    Y+++P   ++V+  + F    L W         
Sbjct: 310 VRD---HDASVYLRLQGDALSVG---GYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEG 363

Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQA 342
           A+  +P L    +     G  + TPD+ P +GE  E   F++  GF+  G M+     Q 
Sbjct: 364 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSVGMMLGGGCGQE 423

Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366
           LA  I+ GR +   D   YD  RF
Sbjct: 424 LAHWIIHGRPE--KDMHGYDIRRF 445


>gi|8923708 hypothetical protein [Homo sapiens] >gi|11437505|ref|XP_006258.1|
           hypothetical protein [Homo sapiens]
           >gi|6048970|gb|AAF02421.1|AF103801_1 (AF103801) unknown
           [Homo sapiens]
           Length = 486
           
 Score =  124 bits (309), Expect = 1e-27
 Identities = 105/396 (26%), Positives = 177/396 (44%), Gaps = 51/396 (12%)

Query: 4   VIGGGIIGVATAYELAKLGEE-----VVVFEKRY-FGSGSTFRCASGIRAQFTDEANIKL 57
           ++GGG++G++ AY L KL        V+V E+ + +   ST     GI  QF+   NI+L
Sbjct: 68  IVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLSVGGICQQFSLPENIQL 127

Query: 58  MKYSIERWKELSEELGH------NIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTK 111
             +S    + ++E L        ++ F  +GYL LA+ E++  A + N+K+Q + G    
Sbjct: 128 SLFSASFLRNINEYLAVVDAPPLDLRFNPSGYLLLAS-EKDAAAMESNVKVQRQEGAKVS 186

Query: 112 LITPEEAKEIVPPLNVEEFLAGAWNPED-GKASPFHTLYAYKKAGEKLGVKFYPYTEVVW 170
           L++P++ +   P +N E     ++  ED G   P+  L   ++  + LGV F       +
Sbjct: 187 LMSPDQLRNKFPWINTEGVALASYGMEDEGWFDPWCLLQGLRRKVQSLGVLFCQGEVTRF 246

Query: 171 IDGG--------------REHKWKIKTTKG----EFEVDVIVNATNAWGSRINSMIGKDI 212
           +                 R H+  +K  +       E  +++NA  AW ++I ++ G   
Sbjct: 247 VSSSQRMLTTDDKAVVLKRIHEVHVKMDRSLEYQPVECAIVINAAGAWSAQIAALAGVGE 306

Query: 213 VPITPFKHQLVKTEPLER-----------GQIEPLVCPPAWNDSYVIQDGEDGGVICGTA 261
            P    +   +  EP +R           G   PLV   +   +Y  ++G     + G +
Sbjct: 307 GPPGTLQGTKLPVEPRKRYVYVWHCPQGPGLETPLVADTS--GAYFRREGLGSNYLGGRS 364

Query: 262 LEYKSDPDDVTPTYD---FVKEVLKWAVKIIPALRHVHVVRQWAGHYA-KTPDNNPAIGE 317
              + +PD      D   F  +V       +PA   + V   WAG+Y   T D N  +G 
Sbjct: 365 PTEQEEPDPANLEVDHDFFQDKVWPHLALRVPAFETLKVQSAWAGYYDYNTFDQNGVVGP 424

Query: 318 --LVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGR 351
             LV + Y A GFSGHG   AP + +A+AE ++KGR
Sbjct: 425 HPLVVNMYFATGFSGHGLQQAPGIGRAVAEMVLKGR 460


>sp|P40875|SAOX_CORS1 SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE OXIDASE SUBUNIT B)
           >gi|2127436|pir||I40887 sarcosine oxidase (EC 1.5.3.1)
           beta chain [validated] - Corynebacterium sp
           >gi|927589|gb|AAC43459.1| (U23955) sarcosine oxidase
           beta subunit [Corynebacterium sp.]
           Length = 405
           
 Score =  123 bits (306), Expect = 3e-27
 Identities = 100/379 (26%), Positives = 165/379 (43%), Gaps = 21/379 (5%)

Query: 4   VIGGGIIGVATAYELAKLG--EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61
           ++GGG  G+ATAY LAK      V V EK +   G+  R  + IR+ +  + +  + + S
Sbjct: 26  IVGGGGHGLATAYYLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLWDESAGIYEKS 85

Query: 62  IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           ++ W++L EEL ++ +F Q G L LA T  +V    + ++     GV  + +TPE+ KE+
Sbjct: 86  LKLWEQLPEELDYDFLFSQRGVLNLAHTLGDVRESVRRVEANKFNGVDAEWLTPEQVKEV 145

Query: 122 VPPLNVEE-----FLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176
            P +N+ +      +   + P  G A   H  +A+ +   ++GV      EV       E
Sbjct: 146 CPIINIGDDIRYPVMGATYQPRAGIAKHDHVAWAFARKANEMGVDIIQNCEVTGFLKDGE 205

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
               +KTT+G      +  A     S +  + G ++ PI     Q + +E  E   + P 
Sbjct: 206 KVTGVKTTRGTIHAGKVALAGAGHSSVLAELAGFEL-PIQSHPLQALVSELFE--PVHPT 262

Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296
           V        YV Q    G ++ G  ++  +        +  ++E +  AV++ P     H
Sbjct: 263 VVMSNHIHVYVSQ-AHKGELVMGAGIDSYNGYGQ-RGAFHVIEEQMAAAVELFPIFARAH 320

Query: 297 VVRQWAGHYAKTPDNNPAIGEL-VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRT--- 352
           V+R W G    T D +P I +  +++ YV  G+   GF   P     LA  I        
Sbjct: 321 VLRTWGGIVDTTMDASPIISKTPIQNLYVNCGWGTGGFKGTPGAGFTLAHTIANDEAHAL 380

Query: 353 KVPLDWEWYDPYRFERGEL 371
             P   E     RFE G L
Sbjct: 381 NAPFSLE-----RFETGHL 394


>gb|AAC48785.1| (AF026954) pyruvate dehydrogenase phosphatase regulatory subunit
           precursor; PDPr [Bos taurus]
           Length = 878
           
 Score =  118 bits (294), Expect = 8e-26
 Identities = 92/367 (25%), Positives = 166/367 (45%), Gaps = 27/367 (7%)

Query: 4   VIGGGIIGVATAYELAKLG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           V GGGI+G + AY L+K+G ++VV+ E+    +GST  CA  +          K+  YS 
Sbjct: 46  VCGGGIMGTSVAYHLSKMGWKDVVLLEQGRLAAGSTRFCAGILSTARHLAIEQKMADYSN 105

Query: 63  ERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIV 122
           + + +L +E G    + +TG +FLA T++ + + K+     N  G+P ++I+P++  E+ 
Sbjct: 106 KLYHQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINSRLNVIGIPCEIISPKKVAELH 165

Query: 123 PPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKIK 182
           P LNV + +     PED   S      A   A  + GV+ Y  T ++ +   +     ++
Sbjct: 166 PLLNVHDLVGAMHVPEDAVVSSADVALALASAASQSGVQIYDRTSILHVMVKKGQVAGVE 225

Query: 183 TTKGEFEVDVIVNATNAWGSRINSMIGKDI-VPITPFKHQLVKTEPLERGQIEPLVCPPA 241
           T KG+ +    VN    W   +     + + +P+   +H  + T P E     PL   P+
Sbjct: 226 TDKGQIQCQYFVNCAGQWAYELGLCSEEPVSIPLHACEHFYLLTRPWE----TPL---PS 278

Query: 242 WNDSYVIQDGE------DGGVICG----------TALEYKSDPDDVTPTYDFVKEVLKWA 285
              + V  DG        GG++ G          T  + + +  ++   +D  + +L   
Sbjct: 279 STPTVVDADGRIYIRNWQGGILSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSL 338

Query: 286 VKIIPALRHVHVVRQWAGHYAKTPDNNPAIGE--LVEDFYVAIGFSGHGFMMAPAVAQAL 343
           ++ +P L  + +V+        TPD    +GE   V  ++V +G +  G        + L
Sbjct: 339 LRRMPQLETLEIVKLVNCPETFTPDMRCIMGESPSVRGYFVLVGMNSAGLSFGGGAGKYL 398

Query: 344 AERIVKG 350
           AE +V G
Sbjct: 399 AEWMVYG 405


>gb|AAK40533.1| Sarcosine oxidase, subunit beta (soxB-like) [Sulfolobus
           solfataricus]
           Length = 372
           
 Score =  118 bits (292), Expect = 1e-25
 Identities = 104/379 (27%), Positives = 178/379 (46%), Gaps = 22/379 (5%)

Query: 1   MIGVIGGGIIGVATAYELAKLG---EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKL 57
           MI ++G G  G++ AY L K G   +++ + E +  G GS+ R A+  R  F  + N++ 
Sbjct: 1   MIIIVGAGSHGLSLAYHLVKKGYSKKDITLVEWKRIGYGSSSRNAARYRYHFYSKENVEY 60

Query: 58  MKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEE 117
              +I   K+ S+EL +N +  +TGYL++   E+E   FKK     + + +  K I   E
Sbjct: 61  AINAISYLKKQSKELEYNSLLLRTGYLWVINGEQEYSLFKKLDSFWSSYNIGGKFI---E 117

Query: 118 AKEIVPPLNVEE--FLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGR 175
            K+    +  E   +LA    P+DG     + LY+Y  + +      Y     +  D  +
Sbjct: 118 CKDNYAYIKFEGQCYLA----PQDGAFHHDYILYSYYYSIKDKVSTIYDKVVSLIKDDSK 173

Query: 176 EHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEP 235
               K+ + K  +   VIV A  AW   + S IG + VPI P K ++  TEPL R  +EP
Sbjct: 174 IKGVKLSSGKELYGDKVIVTA-GAWSGEVLSSIGIE-VPIFPEKKEIYITEPL-RYFLEP 230

Query: 236 LVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHV 295
           L+                G +I G   + +   ++ T +     + LK   ++I  +  +
Sbjct: 231 LIIDSKL--QIYFSQTLKGEIIGGIEDKREYKFEEFTISISNAIKFLKGIRELIKGIDGI 288

Query: 296 HVVRQWAGHYAKTPDNNPAIG---ELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRT 352
            ++R W+G+Y  TPD++  +G   +  E  ++  G+SGHG M AP   + +A+ I     
Sbjct: 289 GILRGWSGYYEMTPDSSQIMGYSNDWPEGLFIDAGYSGHGMMFAPYSGKIMADLIADNYK 348

Query: 353 KVPLDWEWYDPYRFERGEL 371
              +D   + P RF+  +L
Sbjct: 349 NKFID--IFSPSRFKLNKL 365


>gb|AAD13136.1| (AF047004) dimethylglycine dehydrogenase-like protein isoform 1;
           putative sarcosine dehydrogenase [Homo sapiens]
           Length = 431
           
 Score =  115 bits (285), Expect = 9e-25
 Identities = 95/350 (27%), Positives = 159/350 (45%), Gaps = 28/350 (8%)

Query: 4   VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           VIGGG +G  T Y LAKLG    V+ E+    SG+T+  A  +      +  ++L+ ++ 
Sbjct: 71  VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130

Query: 63  ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
               +EL EE G +  + Q G LF+A+  + ++ +K+ + L   +GV + +++P E K +
Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176
            P +NV++     + P DG   P  T     +A    G   ++  P T + VW D  G  
Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
               ++T  G  +   +VN    W S +  M G   VP+    H  V TE +E  Q  P 
Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 309

Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284
           V     +D+ V    +   +  G    Y+++P   ++V+  + F    L W         
Sbjct: 310 VRD---HDASVYLRLQGDALSVG---GYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEG 363

Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHG 332
           A+  +P L    +     G  + TPD+ P +GE  E   F++  GF+  G
Sbjct: 364 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAG 413


>gb|AAF57379.1| (AE003789) CG3270 gene product [Drosophila melanogaster]
           Length = 440
           
 Score =  112 bits (278), Expect = 6e-24
 Identities = 108/382 (28%), Positives = 165/382 (42%), Gaps = 37/382 (9%)

Query: 4   VIGGGIIGVATAYELA----KLGEEV---VVFEKRYFGSGSTFRCASGIRAQFTDEANIK 56
           +IGGG +G ++A+ L     +LG ++   VV     + S ST     G+R QF+   NI+
Sbjct: 36  IIGGGGMGASSAFWLKSRALQLGRKLNVLVVERDAGYTSASTVLSVGGVRQQFSLAENIE 95

Query: 57  LMKYSIERWKELSEELGH-NIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITP 115
           +  +         E LG  ++ +Q  GYL LA+ E+      KN KLQN  G   +L+ P
Sbjct: 96  MSLFGYNFVVNGREHLGDVDLCYQPNGYLILAS-EKGAHILAKNSKLQNELGARNELLGP 154

Query: 116 EEAKEIVPPLNVEEFLAGAWN-PEDGKASPFHTLYAYKKAGEKLGVKFYPYTEV--VWID 172
           E  ++  P L+ E    G     ++G   P+  L  YKK    LG  F   + V   W D
Sbjct: 155 EALRQRFPWLSTEGVELGCHGIDKEGWFDPWALLMGYKKKARALGANFANGSVVGFEWND 214

Query: 173 GGREHKWKI---KTTKGEFEVDVIVNATNAWGSRINSMIG-----------KDIVPITPF 218
            G      +      +   + D  V A  A+  ++  + G              +P+ P 
Sbjct: 215 SGGLSGAVVDAGDVLQRTVKFDTCVLAAGAYSGQVARLAGIGDKEAKEASLSVALPVEPR 274

Query: 219 KH--QLVKTEPLE-RGQIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTY 275
           K    +V T+     G   PL   P  + +Y  +DG  G  +CG +     +P+  T   
Sbjct: 275 KRYVYVVSTQGKNCPGLATPLTVDP--DGTYFRRDGLCGNFLCGRSPNEDEEPECETLDV 332

Query: 276 D---FVKEVLKWAVKIIPALRHVHVVRQWAGHY-AKTPDNNPAIGE--LVEDFYVAIGFS 329
           D   F  +V       +PA   V +   WAG Y   T D N  IG      + ++A GFS
Sbjct: 333 DHGYFETDVWPTLANRVPAFESVKIQSSWAGFYDHNTFDANGVIGRHPHYSNLFIAAGFS 392

Query: 330 GHGFMMAPAVAQALAERIVKGR 351
           GHG    PAV +A++E I+ G+
Sbjct: 393 GHGIQQTPAVGRAISELILDGK 414


>gb|AAF57796.1| (AE003802) CG6385 gene product [Drosophila melanogaster]
           Length = 894
           
 Score =  111 bits (276), Expect = 1e-23
 Identities = 89/371 (23%), Positives = 169/371 (44%), Gaps = 25/371 (6%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63
           VIGGG  G  T Y LA+ G + V+ E+    +G+T+  A  +     ++ +I+L+  S  
Sbjct: 41  VIGGGSAGCHTLYHLARRGVKAVLLERAQLTAGTTWHTAGLLWRLRPNDVDIQLLANSRR 100

Query: 64  RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVP 123
             ++L EE   +  + Q G +F+A  E  ++ +++   + +  G+  ++++PE+ +++ P
Sbjct: 101 MLQQLEEETELDPGWIQNGGIFIAHNETRLDEYRRLATVGSALGIENQVLSPEDTQKLFP 160

Query: 124 PLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK--- 180
            L+   F+   ++P DG   P     A KKA   LG +      V  +   +  + K   
Sbjct: 161 LLDPSAFVGALYSPGDGVMDPAMLCAALKKAATNLGAQVIENCGVDDLLLEQTARGKKVV 220

Query: 181 -IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCP 239
            + T  G+ + + +VNAT  WG  + +  G  + P+ P KH  + +E +   +  P +  
Sbjct: 221 GVSTPFGDIKAEKVVNATGVWGRDLVARHGTHL-PLVPMKHAYIVSESIPGVRGLPNIRD 279

Query: 240 PAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKWAV---------K 287
             ++  + IQ    G  IC     Y+ +P   + V   + F    L W+V         K
Sbjct: 280 HDYSTYFRIQ----GDAICMGG--YEPNPILLEPVPKDFHFGLYELDWSVFETHVEGAQK 333

Query: 288 IIPALRHVHVVRQWAGHYAKTPDNNPAIG--ELVEDFYVAIGFSGHGFMMAPAVAQALAE 345
           + P+     V     G  + TPD+ P +G    ++  Y   GF+  G M      +  A 
Sbjct: 334 LCPSYAKYGVKSTVCGPESFTPDHKPLMGPDPNLDGLYHNCGFNSAGMMFGGGCGEQTAL 393

Query: 346 RIVKGRTKVPL 356
            +++G+  +P+
Sbjct: 394 WVIQGQPDLPM 404


>pir||E72254 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4981997|gb|AAD36502.1|AE001795_5 (AE001795)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 479
           
 Score =  108 bits (267), Expect = 1e-22
 Identities = 88/365 (24%), Positives = 172/365 (47%), Gaps = 14/365 (3%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRY-FGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           VIGGG+ G   A EL K   EV + EK    G G T   ++ + A + D       ++  
Sbjct: 5   VIGGGVFGSLIARELTKYDLEVTLIEKNLDVGWGVTKANSAVVHAGYDDPPESVRAQFCA 64

Query: 63  E---RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVP-TKLITPEEA 118
                +++LS+EL  +  F++ G   +A  +EE++  ++ +K     GVP   ++  +E 
Sbjct: 65  SGNAMYEDLSKELDFD--FKRIGSFVVAFNDEELKELERLLKQGEENGVPGLTILERDEV 122

Query: 119 KEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHK 178
             + P LN E   A  + P  G   P+    A  +   + G+K      VV  +      
Sbjct: 123 LSMEPNLNPEVKYA-LYAPTAGITEPWMVAIAAVENAVQNGLKLVLGESVVGFEKVNGRV 181

Query: 179 WKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVC 238
            K+ T++GE+E D+++N        I  + G + VP+ P K + +  +   +G ++ ++ 
Sbjct: 182 RKVHTSRGEYEADIVINCAGLHADEIAKLAGAEYVPLHPRKGEYILLDKKLQGLVKRVIF 241

Query: 239 PPAWNDS--YVIQDGEDGGVICGTALEYKSD--PDDVTPTYDFVKEVLKWAVKIIPALRH 294
           P     S   ++    DGG++ G   E   +   D    T + +++V ++  +++P+L  
Sbjct: 242 PTPTKISKGILVLPTVDGGILLGPTAEDLPEEMKDRPITTREGLEKVREFTRRLVPSLDF 301

Query: 295 VHVVRQWAGHYAKTPDNN--PAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRT 352
             VV+ ++G   ++P  +    + E V++F   +     G   APAVA+ + E +++ + 
Sbjct: 302 SLVVKTFSGLRPESPQKDFFIKVSETVKNFVNVMATRSPGLTAAPAVAKYVVEELIQEKM 361

Query: 353 KVPLD 357
           ++PL+
Sbjct: 362 RIPLE 366


>gi|10955084 agaE [Agrobacterium tumefaciens] >gi|11352852|pir||T45533 agaE
           protein [imported] - Agrobacterium tumefaciens plasmid
           pTi15955 >gi|2665709|gb|AAB88469.1| (AF242881) agaE
           [Agrobacterium tumefaciens]
           Length = 437
           
 Score =  106 bits (261), Expect = 6e-22
 Identities = 98/420 (23%), Positives = 157/420 (37%), Gaps = 67/420 (15%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63
           VIGGGI+GV+TA ELA+ G  V + EK       + R    +R    D + I L   S+ 
Sbjct: 23  VIGGGIVGVSTALELAERGISVALCEKGLIAGEQSGRNWGWVRQMGRDASEIPLAVESLN 82

Query: 64  RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVP 123
            WK L+  +G    F+QTG  +L     +   ++  +    + G+ ++L+  EE ++ +P
Sbjct: 83  LWKGLNARIGEETGFRQTGIAYLCRNTRQEAEYEAWLVHARKHGLDSRLLKKEELRQHLP 142

Query: 124 PLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKIKT 183
            +  + F A      DG+A P     A  +   + G        V  I+        + T
Sbjct: 143 GM-ADGFTAALHTSTDGRAEPSKAAPAIARGAIRAGAHIITGCAVRSIERSGGAVSGVVT 201

Query: 184 TKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPPAWN 243
            +G      +V A  AW    +  +G D      F    +         +E +   P   
Sbjct: 202 ERGRIACSSVVLAGGAWSRLFSGNMGID------FPQLKILATVARATSVEGVPDMPVGA 255

Query: 244 DSYVIQDGEDG--GVICGTALEYKSDPDDVTPTYDFVKEVLK------------------ 283
           D++  +  +DG   +    A      PD      DF+  ++K                  
Sbjct: 256 DNFSFRRRQDGSFNIAMRNANVAPIVPDSFRLFTDFMPTLIKGWDELTLRVGSRFIEEWR 315

Query: 284 ----WA-----------------------------VKIIPALRHVHVVRQWAGHYAKTPD 310
               WA                             VK  PA     + + WAG    TPD
Sbjct: 316 TPRSWAADAISPFEQVRILDPKPFERFNREGLAHLVKAFPAFADSRITQSWAGLIDVTPD 375

Query: 311 NNPAIGEL--VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEWYDPYRFER 368
             P IG    +  F++A GFSGHGF + P   + +A+ +   +  V        P+RF+R
Sbjct: 376 AIPVIGPAGGIPGFFIASGFSGHGFGIGPGSGKLMADLVTNAQPSVD-----PAPFRFDR 430


>pir||H82968 sarcosine oxidase beta subunit PA5416 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9951743|gb|AAG08801.1|AE004954_3 (AE004954)
           sarcosine oxidase beta subunit [Pseudomonas aeruginosa]
           Length = 416
           
 Score =  105 bits (260), Expect = 8e-22
 Identities = 87/355 (24%), Positives = 159/355 (44%), Gaps = 13/355 (3%)

Query: 4   VIGGGIIGVATAYELAKLG--EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61
           ++GGG  G+ATAY LAK      V V EK + G G+T R  + +R+ +  + +  L +++
Sbjct: 37  IVGGGGHGLATAYYLAKEHGISNVAVVEKGWLGGGNTARNTTIVRSNYLWDESALLYEHA 96

Query: 62  IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           ++ W+ LS++L +N+MF Q G   L  T +++   ++ +      GV  +L+  ++  E 
Sbjct: 97  MKLWEGLSQDLNYNVMFSQRGVYNLCHTLQDMRDGERRVSANRLNGVDGELLNAQQVAEE 156

Query: 122 VPPLNVEE-----FLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176
           +P L+  +      +        G A      + + +A + LGV     TEV        
Sbjct: 157 IPYLDCSKSTRYPIMGATIQRRGGVARHDAVAWGFARAADALGVDLIQQTEVTGFRKQDG 216

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
               ++T +G F     V    A  S   + +    +P+     Q + +EPL +  I+ +
Sbjct: 217 AVIGVETNRG-FIGARRVGVVTAGNSGHMARLAGFRLPLESHPLQALVSEPL-KPIIDSV 274

Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296
           +   A +    I   + G ++ G  ++  +       +Y  ++  L+  V++ P L  V 
Sbjct: 275 IMSNAVHG--YISQSDKGDLVIGAGIDGYNGYGQ-RGSYPVIEHTLQAIVEMFPVLSRVR 331

Query: 297 VVRQWAGHYAKTPDNNPAIGEL-VEDFYVAIGFSGHGFMMAPAVAQALAERIVKG 350
           + RQW G    TPD  P IG+  V++ +   G+   GF   P      A  + KG
Sbjct: 332 MNRQWGGIVDTTPDACPIIGKTPVQNLFFNCGWGTGGFKATPGSGNVFAATLAKG 386


>dbj|BAB05153.1| (AP001512) glycine oxidase (sarcosine oxidase) [Bacillus
           halodurans]
           Length = 365
           
 Score =  103 bits (255), Expect = 3e-21
 Identities = 93/374 (24%), Positives = 168/374 (44%), Gaps = 23/374 (6%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEAN-----IKLM 58
           V+GGG+IG+A A+EL   G +V V E+   G G     A+G+ A F++          L 
Sbjct: 3   VLGGGVIGLAVAFELKVRGHQVTVLEQGLCG-GQASGAAAGMLAPFSEIGEDPNDFFHLA 61

Query: 59  KYSIER---WKELSEEL-GHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLIT 114
             S++    W++  +E+ G +  + Q+G L     E +    +     Q  FGV +++++
Sbjct: 62  HESLKMYPDWQQAVKEISGKSFEYVQSGSLHCVYHEADFLELESRQHWQGTFGVESEILS 121

Query: 115 PEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGG 174
            ++ + + P ++ +E +   + PE+        + A +    KLGV        + I+  
Sbjct: 122 QQQIRALEPNIS-DEIIGAIYYPEESHLFAPDYVKALEIGCRKLGVTIEDEVGHISIEAW 180

Query: 175 REHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIE 234
            EH+     +  ++  D ++    AW S          VP+ P + Q+   E +  G + 
Sbjct: 181 MEHQVLRGPSGKQWAGDRLIVCAGAWASEHEETFSLR-VPVYPIRGQICAYE-VPAGDVR 238

Query: 235 PLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRH 294
            +V     +  Y++  G +G V+ G + +      D T T   +K +  W   I P L  
Sbjct: 239 HIVYT---SQGYIVPKG-NGTVVNGASEDIAG--YDTTVTEQGIKRLTNWNGHIFPFLNE 292

Query: 295 VHVVRQWAGHYAKTPDNNPAIGELVEDFYV--AIGFSGHGFMMAPAVAQALAERIVKGRT 352
           +     WAG    T D  P IGE  +  +V  A G   +G +++P  A+ +A+ +   +T
Sbjct: 293 LTPFHTWAGLRPATQDGYPMIGETKKAPHVVFATGHYRNGILLSPITAKVVADVVEGKKT 352

Query: 353 KVPLDWEWYDPYRF 366
           +VPL    +DP RF
Sbjct: 353 EVPL--TMFDPMRF 364


>sp|O31616|GLOX_BACSU GLYCINE OXIDASE >gi|7475812|pir||B69845 sarcosine oxidase homolog
           yjbR - Bacillus subtilis >gi|2633521|emb|CAB13024.1|
           (Z99110) similar to sarcosine oxidase [Bacillus
           subtilis]
           Length = 369
           
 Score =  102 bits (252), Expect = 7e-21
 Identities = 102/378 (26%), Positives = 170/378 (43%), Gaps = 32/378 (8%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCAS--GIRAQFTD-EANIKLMKY 60
           VIGGGIIG A AY LAK  +   +FE    G  +T   A   G  A+  + +A      +
Sbjct: 9   VIGGGIIGSAIAYYLAKENKNTALFESGTMGGRTTSAAAGMLGAHAECEERDAFFDFAMH 68

Query: 61  SIERWKELSEEL----GHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPE 116
           S   +K L EEL    G +I     G   LA +EE+V   ++   L +         + E
Sbjct: 69  SQRLYKGLGEELYALSGVDIRQHNGGMFKLAFSEEDVLQLRQMDDLDS-----VSWYSKE 123

Query: 117 EAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176
           E  E  P  + + F A ++  +D    P+    AY KA + LG + + +T V+ ++   E
Sbjct: 124 EVLEKEPYASGDIFGA-SFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGE 182

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
             + IKT  G+   + +V A+  W       +G +   +       VK E L     +  
Sbjct: 183 ALF-IKTPSGDVWANHVVVASGVWSGMFFKQLGLNNAFLP------VKGECLSVWNDDIP 235

Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDF--VKEVLKWAVKIIPALRH 294
           +    ++D   I   + G ++ G  ++    P D + T D   ++ V+K A  ++PA+++
Sbjct: 236 LTKTLYHDHCYIVPRKSGRLVVGATMK----PGDWSETPDLGGLESVMKKAKTMLPAIQN 291

Query: 295 VHVVRQWAGHYAKTPDNNPAIGELVEDFYV--AIGFSGHGFMMAPAVAQALAERIVKGRT 352
           + V R WAG    T D  P IG   ED  +  A G   +G ++APA    +++ I+    
Sbjct: 292 MKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILLAPATGALISDLIMNKE- 350

Query: 353 KVPLDWEWYDPYRFERGE 370
              ++ +W   +R +R E
Sbjct: 351 ---VNQDWLHAFRIDRKE 365


>gb|AAD53399.2|AF095736_1 (AF095736) unknown [Homo sapiens]
           Length = 328
           
 Score =  102 bits (252), Expect = 7e-21
 Identities = 71/241 (29%), Positives = 115/241 (47%), Gaps = 8/241 (3%)

Query: 4   VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           VIGGG +G  T Y LAKLG    V+ E+    SG+T+  A  +      +  ++L+ ++ 
Sbjct: 27  VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 86

Query: 63  ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
               +EL EE G +  + Q G LF+A+  + ++ +K+ + L   +GV + +++P E K +
Sbjct: 87  RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 146

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176
            P +NV++     + P DG   P  T     +A    G   ++  P T + VW D  G  
Sbjct: 147 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 206

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
               ++T  G  +   +VN    W S +  M G   VP+    H  V TE +E  Q  P 
Sbjct: 207 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 265

Query: 237 V 237
           V
Sbjct: 266 V 266


>gi|6005868 sarcosine dehydrogenase; dimethylglycine dehydrogenase-like 1 [Homo
           sapiens] >gi|11429603|ref|XP_005639.1| sarcosine
           dehydrogenase [Homo sapiens] >gi|5902972|gb|AAD53400.2|
           (AF095737) unknown [Homo sapiens]
           Length = 396
           
 Score =  101 bits (250), Expect = 1e-20
 Identities = 68/233 (29%), Positives = 112/233 (47%), Gaps = 8/233 (3%)

Query: 4   VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           VIGGG +G  T Y LAKLG    V+ E+    SG+T+  A  +      +  ++L+ ++ 
Sbjct: 71  VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130

Query: 63  ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
               +EL EE G +  + Q G LF+A+  + ++ +K+ + L   +GV + +++P E K +
Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176
            P +NV++     + P DG   P  T     +A    G   ++  P T + VW D  G  
Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLE 229
               ++T  G  +   +VN    W S +  M G   VP+    H  V TE +E
Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIE 302


>gb|AAB03674.1| (U62481) dimethylglycine dehydrogenase-like protein [Rattus
           norvegicus] >gi|1449112|gb|AAB04667.1| (L79910)
           dimethylglycine dehydrogenase [Rattus norvegicus]
           Length = 278
           
 Score = 96.0 bits (235), Expect = 7e-19
 Identities = 66/241 (27%), Positives = 111/241 (45%), Gaps = 8/241 (3%)

Query: 4   VIGGGIIGVATAYELAKLGEEVV-VFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62
           VIGGG +G  T Y LAKLG   V    +R   SG+T+  A  +      +  ++L+ ++ 
Sbjct: 32  VIGGGSLGCQTLYHLAKLGVSGVGAAGERAMTSGTTWHTAGLLWQLRPSDVEVELLAHTR 91

Query: 63  ERWK-ELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           +    +L EE G +  + Q G  F+A+ ++ ++ +K+ + L   +G+ + +++P E K++
Sbjct: 92  QVVSHDLEEETGLHTGWIQNGGFFIASNQQRLDEYKRLMSLGKAYGIESHVLSPAETKDL 151

Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI-----DGGRE 176
            P +NV++     + P DG   P  T     +A    G +      V  I     D G  
Sbjct: 152 YPLMNVDDLYGTLYVPRDGTMDPAGTCTTLTRAAVARGAQVIENCAVTGIRVRTDDFGVR 211

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
               ++T  G  +   +VN    W S +  M G   VP+    H  V TE +E  Q  P 
Sbjct: 212 RVTAVETQHGSIQTPCVVNCAGVWASSVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 270

Query: 237 V 237
           V
Sbjct: 271 V 271


>dbj|BAB05760.1| (AP001514) unknown conserved protein [Bacillus halodurans]
           Length = 376
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 91/363 (25%), Positives = 157/363 (43%), Gaps = 37/363 (10%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFG-------SGSTFRCASGI-RAQFTDEANI 55
           +IGGG+IG++ A   AK G  V+V EK   G       +G     A G+ R       + 
Sbjct: 9   IIGGGVIGLSIAIHTAKKGANVLVVEKDRLGQEASGGRAGLLTTVAEGVDRHDPYSIFSR 68

Query: 56  KLMKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITP 115
           + ++Y ++   EL E+   +    +   L LA  E+E    + +  +Q       K ++ 
Sbjct: 69  ESLQYLLQWIPELEEKTQISSGLVKQNLLRLALHEQEAALLEDHWLMQTETNSQIKRLSA 128

Query: 116 EEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGR 175
           EEA+ + P L+  + +    +P++    P   L A  +   +LGV     TEV+      
Sbjct: 129 EEARTLEPLLS-NDLIMAICSPDEYHLEPSLYLNALARMARQLGVTIREQTEVIQFIHQN 187

Query: 176 EHKWKIKTTKG-EFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIE 234
              + + T  G +   +  + A  AW S + S + K  VP+ P K QL+    L++G  +
Sbjct: 188 NRMYGVVTNTGTQIVAETTILAAGAW-SHLLSRLAKVKVPVYPLKGQLI---VLKQGDTD 243

Query: 235 PLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVT--------PTYDFVKEVLKWAV 286
             V     +  Y++    +G V+ G   E +     +T        P +D+V E+  W +
Sbjct: 244 LNVMINT-SKGYILSK-PNGTVVLGATSEKEKFNKFITAKGIQELLPLFDYVPELKNWEI 301

Query: 287 KIIPALRHVHVVRQWAGHYAKTPDNNPAIGELV--EDFYVAIGFSGHGFMMAPAVAQALA 344
           + +           WAG    TPD  P IG +   E +Y+A G S HG +++      +A
Sbjct: 302 QHL-----------WAGLRPATPDGQPIIGYVPEWEGWYLATGHSRHGVLLSGWTGHLVA 350

Query: 345 ERI 347
           E +
Sbjct: 351 EEL 353


>sp|O87388|SAOX_RHIME SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE OXIDASE SUBUNIT B)
           >gi|3687680|gb|AAC62218.1| (AF055582) sarcosine oxidase
           subunit B [Sinorhizobium meliloti]
           Length = 416
           
 Score = 92.4 bits (226), Expect = 8e-18
 Identities = 95/376 (25%), Positives = 159/376 (42%), Gaps = 16/376 (4%)

Query: 4   VIGGGIIGVATAYELAK-LG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61
           ++GGG  G+ATAY LAK  G   V V EK Y GSG+  R  + IR+ +    N    + S
Sbjct: 36  IVGGGGHGLATAYYLAKEFGITNVAVLEKNYIGSGNVGRNTTIIRSNYLLPGNNPFYELS 95

Query: 62  IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
           ++ W+ L ++   N M  Q G L L  ++ + +A+ +        GV  +L+     +++
Sbjct: 96  MKLWEGLEQDFNFNAMVSQRGVLNLFHSDAQRDAYTRRGNAMRLHGVDAELLYRAAVRKM 155

Query: 122 VPPLNVEE----FLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREH 177
           +P L+ +        G      G        + Y +  +  GV      EV  I      
Sbjct: 156 LPFLDFDNARFPIQGGLLQRRGGTVRHDAVAWGYARGADSRGVDIIQNCEVTGIRRENGR 215

Query: 178 KWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLV 237
              ++T++G      +  A     S++  M G  + PI     Q   +E L +  I+ +V
Sbjct: 216 VIGVETSRGFIGCAKLALAAAGNSSQVAEMAGLRL-PIESHVLQAFVSEGL-KPFIDGVV 273

Query: 238 CPPAWNDSYVIQDGEDGGVICGTALE-YKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296
              A +  + +   + GG++ G  ++ Y S           V+ V +    +IPAL  V 
Sbjct: 274 TFGAGH--FYVSQSDKGGLVFGGDIDGYNSYAQ--RGNLATVEHVAEAGKAMIPALSRVR 329

Query: 297 VVRQWAGHYAKTPDNNPAIGEL-VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVP 355
           V+R W G    + D +P I    +++ Y+  G+   GF   PA     A  + +G  +  
Sbjct: 330 VLRSWGGIMDMSMDGSPIIDRTPIDNLYLNAGWCYGGFKATPASGFCFAHLLARGAPQKT 389

Query: 356 LDWEWYDPYRFERGEL 371
                 D  RFERG L
Sbjct: 390 AAAFRLD--RFERGFL 403


>pir||F83487 hypothetical protein PA1267 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9947200|gb|AAG04656.1|AE004556_6
           (AE004556) hypothetical protein [Pseudomonas aeruginosa]
           Length = 371
           
 Score = 92.1 bits (225), Expect = 1e-17
 Identities = 99/378 (26%), Positives = 165/378 (43%), Gaps = 37/378 (9%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63
           V+G GI+G A A+ELA+ G +V+V + R    G+T      + A   + A + L  YS +
Sbjct: 7   VVGAGIVGSACAHELARRGLDVLVLDSRR--GGATAVGMGHLVAMDDNPAELALSDYSTQ 64

Query: 64  RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVP 123
            W+  + EL  +  ++  G L+LA    E+   ++  +     GV  +++       + P
Sbjct: 65  AWRAWAAELPEDCAYRGCGTLWLAADASELAEAERKRQALQAAGVACRMLGAARLYALEP 124

Query: 124 PLNVEEFLAGAWNPE-DGKA-SPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181
            L     LAGA     DG   +P    +   +AG +L      Y EV  +DG R     +
Sbjct: 125 ALRPG--LAGALEVSGDGILYAPNAARWLLDQAGPRLRRL---YAEVSEVDGSR-----L 174

Query: 182 KTTKGEF-EVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEP---------LERG 231
           +   G +   + +V A       + + +     PI P K  L+ T+          +E G
Sbjct: 175 RLADGRWLSAEALVLANGIHAGELCAEL-----PIRPKKGHLLITDRYPGTLRHQLVELG 229

Query: 232 QIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKS-DPDDVTPTYDFVKEVLKWAVKIIP 290
            +         + ++  Q    G V  G++ ++ + DP    P    +  +L+ A+  +P
Sbjct: 230 YVSSAHASSGTSVAFNAQPRPTGQVFLGSSRQFDTLDPQVEGPV---LARMLRRALDYLP 286

Query: 291 ALRHVHVVRQWAGHYAKTPDNNPAIGE--LVEDFYVAIGFSGHGFMMAPAVAQALAERIV 348
            L  ++ +R W G  A TPD  P +GE       ++A+G  G G   AP  A+ LA ++ 
Sbjct: 287 GLAGLNAIRAWTGFRAATPDGLPLLGEHPAQPGLWLAVGHEGLGVTTAPGSARLLAAQLF 346

Query: 349 KGRTKVPLDWEWYDPYRF 366
            G T  PLD   Y P RF
Sbjct: 347 -GETP-PLDPTPYLPQRF 362


>pir||H83370 hydrogen cyanide synthase HcnC PA2195 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|6644364|gb|AAF21030.1|AF208523_3 (AF208523) HcnC
           [Pseudomonas aeruginosa]
           >gi|9948217|gb|AAG05583.1|AE004646_4 (AE004646) hydrogen
           cyanide synthase HcnC [Pseudomonas aeruginosa]
           Length = 417
           
 Score = 90.9 bits (222), Expect = 2e-17
 Identities = 82/313 (26%), Positives = 142/313 (45%), Gaps = 23/313 (7%)

Query: 63  ERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIV 122
           E  +EL E  G +  F++TG  ++   +E+ +  +  +          + +  EE +   
Sbjct: 109 ELHRELIERHGMDFKFERTGLKYVIQDDEDRQYAEHIVAQIPHLAEQVRWLDREELRRAE 168

Query: 123 PPLN-----VEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI-DGGRE 176
           P ++       EFL       D + SPF    AY +A  + GV+  P T V  +   GR 
Sbjct: 169 PAVSHAAHGALEFLC------DHQVSPFRLADAYLEAARQNGVELLPGTNVTGVLRQGRR 222

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236
                    G      ++NA  AW + ++ M     +P+ P K Q+V TE + R     L
Sbjct: 223 ISGVRTDNAGVLHCRTLINAAGAWAAELSEMATGRRIPVKPVKGQIVLTERMPRLLNGCL 282

Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296
                 +D Y+ Q  ++G ++ G+  E K    DV+ T+  +  +++ AV+ +P L+ V+
Sbjct: 283 TT----SDCYMAQK-DNGEILIGSTTEDKGF--DVSNTFPEIAGLVQGAVRCVPELQQVN 335

Query: 297 VVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKV 354
           + R WAG    +PD  P +G +  VE +  A G    G ++  A+   L +R+V   T +
Sbjct: 336 LKRTWAGLRPGSPDELPILGPVAEVEGYLNACGHFRTG-ILTSAITGVLLDRLVHEET-L 393

Query: 355 PLDWEWYDPYRFE 367
           PLD   +   RF+
Sbjct: 394 PLDIAPFLAARFQ 406


>gb|AAK42656.1| Glycerol-3-phosphate dehydrogenase chain A (glpA) [Sulfolobus
           solfataricus]
           Length = 445
           
 Score = 89.7 bits (219), Expect = 5e-17
 Identities = 82/311 (26%), Positives = 142/311 (45%), Gaps = 20/311 (6%)

Query: 2   IGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFR----CASGIRAQFTDEANIKL 57
           + VIGGG+ G+ TA +LA  G +V + ++   G G++ +      SG R   TD  + + 
Sbjct: 20  VTVIGGGVSGLFTALDLALRGIDVTLVDRGDIGYGTSGKFHGLLHSGARYAVTDPDSAR- 78

Query: 58  MKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEE 117
               I+  K +S+   H +  + TG +FL  T+++++  +  IK  N+ G+ +K+I  +E
Sbjct: 79  --ECIQENKIISKIAPHTV--KDTGGVFLGITDDDLQFSETFIKALNKVGIESKVIDVKE 134

Query: 118 AKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI------ 171
             +  P +N +  +A  W P D     +  L +        G K   Y EVV I      
Sbjct: 135 VLQKEPFINRDTKMA-IWVP-DKVVYGYDLLASVAITASLNGAKILTYNEVVEIIRENNN 192

Query: 172 DGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERG 231
             G +   KI       + D+IVN    W   I  M G + +PI P    +V  +     
Sbjct: 193 VKGVKVLDKINNNTNVIKSDIIVNTAGPWSFNIIKMAGLEEIPIMPTAGIIVVFDKRVNN 252

Query: 232 QIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPA 291
            +   + PP  +D  +I    D  ++ GT      DPD+ T + + +  ++     +IP 
Sbjct: 253 MVINRLRPP--SDGDIIVPYADSSIL-GTTATIIEDPDNFTISDEDIAMLVNEGAYLIPK 309

Query: 292 LRHVHVVRQWA 302
           L+++ VVR +A
Sbjct: 310 LKNMRVVRSYA 320


>sp|Q52671|SAOX_RHOCA SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE OXIDASE SUBUNIT B)
           >gi|1353872|gb|AAB01814.1| (U46071) sarcosine oxidase
           [Rhodobacter capsulatus]
           Length = 208
           
 Score = 86.6 bits (211), Expect = 4e-16
 Identities = 52/171 (30%), Positives = 88/171 (51%), Gaps = 6/171 (3%)

Query: 4   VIGGGIIGVATAYELAKLG--EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61
           V+G G  G+ATAY L K+   + V + EK + G G+T R  + IR+ +  + +  + + +
Sbjct: 37  VVGAGGHGLATAYYLGKVHGIKNVAIIEKGWLGGGNTGRNTTIIRSNYLQDPSAAIYEKA 96

Query: 62  IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121
              ++ LS++L +N+MF   G L LA +E E+  +K+ +   N   V T+ I P+E K++
Sbjct: 97  RSLYEGLSQDLNYNVMFSPRGLLMLAQSEHEMRGYKRTVYANNLQNVETRWIEPKEVKKL 156

Query: 122 VPPLNVE----EFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEV 168
           VP LN+       L      + G A      + Y +A   +G+     TEV
Sbjct: 157 VPILNIAGPRYPVLGALLQEKGGTARHDAVAWGYARACSDMGMDLLQNTEV 207


>pir||E82983 probable oxidoreductase PA5309 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9951625|gb|AAG08694.1|AE004943_10
           (AE004943) probable oxidoreductase [Pseudomonas
           aeruginosa]
           Length = 439
           
 Score = 82.7 bits (201), Expect = 7e-15
 Identities = 91/375 (24%), Positives = 159/375 (42%), Gaps = 53/375 (14%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRC--------------------AS 43
           V+GGG  GV TA ELA+ G  VV+ E    G G++ R                     A 
Sbjct: 42  VVGGGFSGVNTALELAQRGFSVVLLEAHQIGWGASGRNGGQLIRGVGHDVEQFLPVIGAD 101

Query: 44  GIRAQFTDEANIKLMKY-SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKL 102
           G++A       +KLM   ++E  +   E+   +   +  GY  LA    + + F+++++ 
Sbjct: 102 GVKA-------LKLMGLEAVEIVRRRVEQYAIDCDLRW-GYCDLANKPGDYQGFREDMEE 153

Query: 103 QNRFGV--PTKLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGV 160
               G     +L+   E + ++     + ++ G  +   G   P + +     A + LGV
Sbjct: 154 LQALGYRHEMRLVPAAEMRSVI---GSDRYVGGLVDMGSGHLHPLNLVLGEAAAAQSLGV 210

Query: 161 KFYPYTEVVWIDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKH 220
           + +  + V+ ID G E +  + T  G+     +V   NA+ + +N ++G  ++P   +  
Sbjct: 211 RLFERSTVMRIDYGTEVQ--VHTATGKVRAKTLVLGCNAYMNDLNPLLGGKVLPAGSY-- 266

Query: 221 QLVKTEPLERGQIEPLVCP-PAWNDSYVIQD----GEDGGVICGTALEYKS-DPDDVTPT 274
            ++ TEPL+      L+    A  D  V  D      D  ++ G A  Y   DP D+   
Sbjct: 267 -VIATEPLDEKLARQLLPQNMAVCDQRVALDYYRLSADNRLLFGGACHYSGRDPSDIAA- 324

Query: 275 YDFVKEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHG 332
             +++  +   +++ P L +V +  QW G      +  P IG L    + Y A  +SGHG
Sbjct: 325 --YMRPKM---LEVFPQLANVRIDYQWGGMIGIGANRLPQIGRLPGQPNVYFAQAYSGHG 379

Query: 333 FMMAPAVAQALAERI 347
                   Q LAE I
Sbjct: 380 VNATHLAGQLLAEAI 394


>gb|AAC38596.1| (AF053760) hydrogen cyanide synthase HcnC [Pseudomonas fluorescens]
           Length = 417
           
 Score = 82.7 bits (201), Expect = 7e-15
 Identities = 99/403 (24%), Positives = 168/403 (41%), Gaps = 64/403 (15%)

Query: 4   VIGGGIIGVATAYELAKLGE-EVVVFEKRYFGSGST---------------------FRC 41
           + GGG+IG + AY+L+K  + +V + + +  G+ S                      FR 
Sbjct: 9   IAGGGVIGASCAYQLSKRKDLKVALIDAKRPGNASRASAGGLWAIGESVGLGCGVIFFRM 68

Query: 42  ASGIR-------AQFTDEANIKLMKYSI--------ERWKELSEELG--HNI--MFQQTG 82
            S  R       A   D +   ++  S         E +  L  EL   HN+   F+QTG
Sbjct: 69  MSANRKREAQGSAVVVDSSTPHILPQSFFDFALQSNELYPRLHRELMGLHNMDFKFEQTG 128

Query: 83  YLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVPPLNVE-----EFLAGAWNP 137
             F+   EE+    +  +          + +     +   P ++ E     EFL      
Sbjct: 129 LKFVIYDEEDRLYAEHIVGCIPHLSDQVRWLDQAALRASEPNVSHEAQGALEFLC----- 183

Query: 138 EDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKIKT-TKGEFEVDVIVNA 196
            D + +PF    AY +   + GV  Y  T V  +         +KT   G F    ++NA
Sbjct: 184 -DHQVNPFRLTDAYTEGARQNGVDVYFNTNVTGVLHQGNRVSGVKTDVAGLFRCTTLINA 242

Query: 197 TNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPPAWNDSYVIQDGEDGGV 256
             AW + ++       +P+ P K Q++ TE + +     L      +D Y+ Q  ++G +
Sbjct: 243 AGAWAAELSLQATGIEIPVKPVKGQILLTERMPKLLNGCLTT----SDCYMAQK-DNGEI 297

Query: 257 ICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIG 316
           + G+  E K    DVT TY  +  +++ AV+ +P L HV++ R WAG    +PD  P +G
Sbjct: 298 LIGSTTEDKGF--DVTTTYPEINGLVQGAVRCVPELAHVNLKRCWAGLRPGSPDELPILG 355

Query: 317 EL--VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLD 357
            +  VE +  A G    G ++  A+   L +++V     +PLD
Sbjct: 356 PMDGVEGYLNACGHFRTG-ILTSAITGVLLDKLV-NEEALPLD 396


>pir||H70361 conserved hypothetical protein aq_707 - Aquifex aeolicus
           >gi|2983300|gb|AAC06892.1| (AE000703) hypothetical
           protein [Aquifex aeolicus]
           Length = 353
           
 Score = 81.9 bits (199), Expect = 1e-14
 Identities = 101/376 (26%), Positives = 175/376 (45%), Gaps = 40/376 (10%)

Query: 4   VIGGGIIGVATAYELAKLGEEV--VVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61
           VIGGG+IG++   EL   G +V  +V +KR    G+++  A G+ A F++      +++S
Sbjct: 5   VIGGGVIGLSIGVELLLAGHDVRLLVRDKR---EGASW-VAGGMLAPFSEGLRGDFLRFS 60

Query: 62  IER---WKELSEEL----GHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLIT 114
           +E    W +  E L    G  + F Q G L +A  E+E +  ++++K  ++  V   LI+
Sbjct: 61  VESLRLWHDYLERLKEISGRKVFFSQ-GILRVAFDEKEEKKLREDVKFYSQ-EVCQNLIS 118

Query: 115 PEEAKEIVP--PLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWID 172
             +A+E++   P    E   G    ++G       + A   A EKLG +      V  + 
Sbjct: 119 -YDAEELLKEFPYLSSEVRYGVIYGDEGNVDTEELMEALYVAFEKLGGEIINEDAVKILR 177

Query: 173 GGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTE-PLERG 231
            G E   K+     EF  D  V AT AW   +    G    P+ P K Q+++ E PL+  
Sbjct: 178 NG-ERIEKVFGFFEEFTADYYVFATGAW---LKEHFG---FPVFPVKGQILRVEAPLKDY 230

Query: 232 QIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPA 291
            +         + +Y+I   +D  ++ G   E  +   D   T + VK++ + A+  +P 
Sbjct: 231 VVYS-------SRAYIIPREKD--LLIGATTE--NAGFDTKTTLEGVKKLSEGAISSVPQ 279

Query: 292 LRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGR 351
           L+   ++    G    TPD  P +    E+F V  G   +G ++APA A+   + I +G 
Sbjct: 280 LKEAQLLEVRVGFRPGTPDELP-VFYFGENFSVYGGHYRNGILLAPATAEVALKLIDQG- 337

Query: 352 TKVPLDWEWYDPYRFE 367
            +V   ++ + PYRF+
Sbjct: 338 -EVSEYFKTFSPYRFK 352


>pir||C83407 hypothetical protein PA1918 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9947911|gb|AAG05306.1|AE004617_10
           (AE004617) hypothetical protein [Pseudomonas aeruginosa]
           Length = 466
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 89/362 (24%), Positives = 155/362 (42%), Gaps = 46/362 (12%)

Query: 2   IGVIGGGIIGVATAYELAKLGEE--VVVFEKRYFGSGSTFRCAS---------GIRAQFT 50
           + ++GGG +G+ TA  L +L  +  V++ E+   G G++ R            G    F 
Sbjct: 36  VAIVGGGFVGLWTAITLKQLEPDARVLLLEQDVCGGGASGRNGGFVMSWWPKIGTLLGFC 95

Query: 51  DEANIKLMKYSIERW-KELSEELG-HNI--MFQQTGYLFLATTEEEVEAFKKNIKLQNRF 106
            EA  + +  S ER  +EL E    H+I   FQQ G+L+ ATT   ++A+   +    R 
Sbjct: 96  SEAQARFLGESAERAIQELGEFCARHDIDAHFQQKGWLWTATTAHHLDAWNDTLAACERL 155

Query: 107 GVPT--KLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYP 164
           GV    +L   E A+    P++    LAG +   +    P   +   ++    LGV+ + 
Sbjct: 156 GVSPFERLDASEVARRTGSPVH----LAGVFERSNATVQPALLVQGMRRVALALGVEIHE 211

Query: 165 YTEVVWIDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVK 224
              V  I  G+  +  + +     +   +V ATNAW + +   + + IVP+      +  
Sbjct: 212 RCGVSQIVPGQPAQ--LLSAGARVQAKAVVLATNAWSAAL-PRLSRLIVPVNS---SIAV 265

Query: 225 TEPLERGQIEPLVCPPAWNDSYVIQDGE----------DGGVICGTALEYKSDPDDVTPT 274
           TE + + ++E +     W     I D +          DG +  G      S    +   
Sbjct: 266 TEAIPQ-RLERI----GWTGGEAITDSQLMVDYYRTTRDGRIAFGKGTGALSYGSRIGRV 320

Query: 275 YDFVKEVLKWAV----KIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSG 330
           +D  +E L        +  P+L  + +V  W+G   +T D+ P  G L E+ +  IG+SG
Sbjct: 321 FDVDRESLALTEADFRRTYPSLGDIPLVDGWSGPIDRTYDSLPVFGRLHENIHYGIGWSG 380

Query: 331 HG 332
           +G
Sbjct: 381 NG 382


>pir||G83298 conserved hypothetical protein PA2776 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9948857|gb|AAG06164.1|AE004705_6 (AE004705)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 427
           
 Score = 79.2 bits (192), Expect = 7e-14
 Identities = 88/368 (23%), Positives = 150/368 (39%), Gaps = 42/368 (11%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANI---KLMKY 60
           VIG G  G++TA  L + G +V V E    G G++ R    I   ++ + ++    + K 
Sbjct: 34  VIGAGYTGLSTALFLLENGFKVTVLEAAKVGFGASGRNGGQIVNSYSRDIDVIERTVGKR 93

Query: 61  SIERWKELSEELGHNIMFQQTGY----------LFLATTEEEVEAFKKNIKLQNRFGVPT 110
             +   E++ E G  I  +   Y          +F A TE++++  +   +L  R+G   
Sbjct: 94  EAQLLGEMAFEGGRIIRERVARYGIQCDLKDGGVFAAFTEKQMDHLRAQKQLWERYGHNQ 153

Query: 111 KLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVW 170
             I   +AK I   +  + ++ G  +   G   P +       A E LG + Y  +    
Sbjct: 154 LEIM--DAKRIREVVATDNYIGGMLDMSGGHIHPLNLALGEAAAVESLGGRIYEQSPATR 211

Query: 171 IDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLER 230
           I+ G      + T +G+ +   IV A NA+   +N ++ +      P   Q++ TEPL  
Sbjct: 212 IERGASPV--VHTPQGKVKAKFIVVAGNAY---LNGLVPELAAKSMPCGTQVITTEPLNE 266

Query: 231 GQIEPLV----CPPAWN---DSYVIQDGE----DGGVICGTALEYKSDPDDVTPTYDFVK 279
                L+    C    N   D Y +   +     GGVI G       DP D+        
Sbjct: 267 ELAHSLLPQDYCVEDCNYLLDYYRLSGDKRLIYGGGVIYGAR-----DPADIEAI----- 316

Query: 280 EVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAV 339
            +    +K  P L+ V +   W G++  T    P +G + ++ Y + G SGHG       
Sbjct: 317 -IRPKMLKTFPQLKDVKIDFAWTGNFLLTLSRLPQVGRIGDNIYYSQGCSGHGVTYTHVA 375

Query: 340 AQALAERI 347
            + LAE +
Sbjct: 376 GKVLAEAL 383


>gb|AAG20146.1| (AE005092) glycerol-3-phosphate dehydrogenase chain A; GpdA2
           [Halobacterium sp. NRC-1]
           Length = 570
           
 Score = 79.2 bits (192), Expect = 7e-14
 Identities = 88/321 (27%), Positives = 143/321 (44%), Gaps = 34/321 (10%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCA----SGIRAQFTDEANIKLMK 59
           V+GGG  G   A +LA  G  V + E+     G+T R      SG R   +D+A+ +  +
Sbjct: 9   VVGGGSTGAGVARDLAMRGLGVTLVEQGNLTHGTTGRMHGLLHSGGRYAVSDQASAR--E 66

Query: 60  YSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAK 119
             IE  + L E   H +   +TG LF+   E+  + F++ +       +PTK+++  EA+
Sbjct: 67  CIIEN-RVLREIATHCV--DETGGLFVKRPEDSEQYFQEKLAGCEACDIPTKVLSGAEAR 123

Query: 120 EIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPY---TEVVWIDGG-- 174
           ++ P L  ++     W P D    PF  + A   + ++ G +   +   T+VV  DG   
Sbjct: 124 QLEPHL-ADDVEKAIWVP-DAAIDPFRLVVANAASAQEHGARIETHSTVTDVVVEDGAVV 181

Query: 175 ---REHKW----KIKTTKGEFEV---DVIVNATNAWGSRINSMIGKDIVPITPFKHQLVK 224
               EH      ++  T+G  EV   D +VNA  AW  R+  M G D V + P K  +  
Sbjct: 182 GVEVEHATGAGKRVHGTEGGTEVIRADHVVNAAGAWAGRLGEMAGVD-VEVRPSKGVMT- 239

Query: 225 TEPLERGQIEPLV--CPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVL 282
              +   Q++ +V  C P  +   V+    +   I GT  E  +DP+D       V  V+
Sbjct: 240 --VMNTRQVDTVVNRCRPKGDADIVVP--HETTCILGTTDEEVADPEDYPEQQWEVDMVI 295

Query: 283 KWAVKIIPALRHVHVVRQWAG 303
               ++IP L     VR + G
Sbjct: 296 DELAELIPMLDDARTVRSFWG 316


>pir||S76505 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1001620|dbj|BAA10351.1| (D64002) ThiG protein
           [Synechocystis sp.]
           Length = 656
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 90/354 (25%), Positives = 151/354 (42%), Gaps = 29/354 (8%)

Query: 4   VIGGGIIGVATAYELAKLGE---EVVVFEKRYFGSGSTFRCASGIRAQFTDEAN----IK 56
           +IGGGIIG+A A EL KL +   +V V  + +  + S    A+G+ A   ++      + 
Sbjct: 9   IIGGGIIGLAIAVEL-KLKQKRLQVTVLSRDFAQAAS--HAAAGMLAPHAEQIAPGPMLD 65

Query: 57  LMKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPE 116
           L   S  R+ E  E+L   +   +TGY          EA   N    + +      +  E
Sbjct: 66  LCLASRWRYGEWVEKL-EQLTGMETGYNPCGILSPVFEAPHGNSSTNSAW------LDQE 118

Query: 117 EAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176
             +   P L  E+ + G W+P+DG+      + A ++A + LGV+      V  I     
Sbjct: 119 TIRYYQPGLG-EDVIGGWWHPDDGQVDNRKLVSALRQAAQSLGVQIQEGVTVQAIAQRHG 177

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTE-PLERGQIEP 235
               + T +G F+ D  V A  +W   +  +      P+ P K Q++    P    Q  P
Sbjct: 178 QVTAVLTDQGSFQADSYVLANGSWAKELLPL------PVFPVKGQMMALRMPAGTHQPYP 231

Query: 236 LVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHV 295
           L        +Y++    DG +I G   E        TP    ++ +L  A+++ PAL   
Sbjct: 232 LQRVLFGPQTYLV-PRRDGRLIVGATSEQVDWQPHNTP--QGIQTLLGRAIRLFPALGDW 288

Query: 296 HVVRQWAGHYAKTPDNNPAIG-ELVEDFYVAIGFSGHGFMMAPAVAQALAERIV 348
            +   W G    TPD  P +G    ++  +AIG   +G ++AP  A  +++ I+
Sbjct: 289 AIEDFWWGFRPGTPDEQPFLGYGPCDNLILAIGHYRNGILLAPITAALISDLIL 342


>gb|AAA96395.1| (U38892) N-terminal and C-terminal ends are similar to the proteins
           ThiG and D-amino acid dehydrogenase small subunits from
           Escherichia coli, respectively; Method: conceptual
           translation supplied by author; ORF656 [Synechocystis
           sp.]
           Length = 656
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 90/354 (25%), Positives = 151/354 (42%), Gaps = 29/354 (8%)

Query: 4   VIGGGIIGVATAYELAKLGE---EVVVFEKRYFGSGSTFRCASGIRAQFTDEAN----IK 56
           +IGGGIIG+A A EL KL +   +V V  + +  + S    A+G+ A   ++      + 
Sbjct: 9   IIGGGIIGLAIAVEL-KLKQKRLQVTVLSRDFAQAAS--HAAAGMLAPHAEQIAPGPMLD 65

Query: 57  LMKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPE 116
           L   S  R+ E  E+L   +   +TGY          EA   N    + +      +  E
Sbjct: 66  LCLASRWRYGEWVEKL-EQLTGMETGYNPCGILSPVFEAPHGNSSTNSAW------LDQE 118

Query: 117 EAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176
             +   P L  E+ + G W+P+DG+      + A ++A + LGV+      V  I     
Sbjct: 119 TIRYYQPGLG-EDVIGGWWHPDDGQVDNRKLVSALRQAAQSLGVQIQEGVTVQAIAQRHG 177

Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTE-PLERGQIEP 235
               + T +G F+ D  V A  +W   +  +      P+ P K Q++    P    Q  P
Sbjct: 178 QVTAVLTDQGSFQADSYVLANGSWAKELLPL------PVFPVKGQMMALRMPAGTHQPYP 231

Query: 236 LVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHV 295
           L        +Y++    DG +I G   E        TP    ++ +L  A+++ PAL   
Sbjct: 232 LQRVLFGPQTYLV-PRRDGRLIVGATSEQVDWQPHNTP--QGIQTLLGRAIRLFPALGDW 288

Query: 296 HVVRQWAGHYAKTPDNNPAIG-ELVEDFYVAIGFSGHGFMMAPAVAQALAERIV 348
            +   W G    TPD  P +G    ++  +AIG   +G ++AP  A  +++ I+
Sbjct: 289 AIEDFWWGFRPGTPDEQPFLGYGPCDNLILAIGHYRNGILLAPITAALISDLIL 342


>sp|P44732|ORDL_HAEIN PROBABLE OXIDOREDUCTASE ORDL >gi|1073832|pir||F64072 probable
           oxidoreductase (EC 1.-.-.-) HI0499 - Haemophilus
           influenzae (strain Rd KW20) >gi|1573476|gb|AAC22156.1|
           (U32731) oxidoreductase, putative [Haemophilus
           influenzae Rd]
           Length = 431
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 91/378 (24%), Positives = 159/378 (41%), Gaps = 58/378 (15%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRA-------------QFT 50
           VIG G  G++ A ELA+ G++V+V E    G G++ R  SG +A             Q  
Sbjct: 37  VIGAGFFGLSAALELAEKGKKVIVLEGARVGFGASGR--SGGQAINGFEEGIDEYIKQVG 94

Query: 51  DEANIKLMKYSIERWKELSEELG-HNIMFQ-QTGYLFLATTEEEVEAFKKNIKLQNR-FG 107
           ++   KL   S+E    + E +  ++I    + GY  LA  E  ++   +  K  ++ FG
Sbjct: 95  EDKAHKLWNMSLETIDIIDERIEKYSIQCDWKKGYATLALNERRMDDLIEMEKESHKNFG 154

Query: 108 VPTKLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFY---P 164
                +   +  ++   L  + ++ G ++   G   P +      KA   LGV+ +   P
Sbjct: 155 YQNMQLW--DKTKLKQHLGSDIYVGGLFDSNSGHLHPLNYCLGLAKACVDLGVQIFEQSP 212

Query: 165 YTEVVWIDGGREHKWKIKTTKGEFEVDVIVNATNAW----GSRINSMIGKDIVPITPFKH 220
             ++V  +G  E    +KT K       ++ ATNA+       I+  I + I+P+  F  
Sbjct: 213 VVDMVEKNGCVE----VKTAKSAVISQDVILATNAYIDVLPKSIHHGINRKILPVESF-- 266

Query: 221 QLVKTEPLERGQIEPLVCPPAWNDSYVIQDGEDGGVICGTAL---EYKSDPD-------D 270
            ++ TEPL +   + ++               +G  +C   L    Y+   D       D
Sbjct: 267 -IIATEPLSQAVADSVI--------------NNGMSVCDNNLLLDYYRLSADNRLLFGSD 311

Query: 271 VTPTYDFVKEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSG 330
            +   D V  + K  + + P L +V +   WAG    T ++ P  G +    Y A G+SG
Sbjct: 312 SSSEKDMVAIMRKNMLCVFPQLENVKIDYGWAGPIDMTLNSTPHFGRISPHIYFAHGYSG 371

Query: 331 HGFMMAPAVAQALAERIV 348
           HG  +     + +AE I+
Sbjct: 372 HGVALTGLAGRIVAEAIL 389


>sp|O32159|YURR_BACSU HYPOTHETICAL 39.4 KD OXIDOREDUCTASE IN HOM-MRGA INTERGENIC REGION
           >gi|7475684|pir||A70019 opine catabolism homolog yurR -
           Bacillus subtilis >gi|2635760|emb|CAB15253.1| (Z99120)
           similar to opine catabolism [Bacillus subtilis]
           Length = 372
           
 Score = 76.1 bits (184), Expect = 6e-13
 Identities = 94/379 (24%), Positives = 158/379 (40%), Gaps = 36/379 (9%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGI----RAQFTDEANIKLMK 59
           ++G GI+G +TAY LAK G  V V +++  G  +    A+GI     +Q  ++   +L K
Sbjct: 6   IVGAGILGASTAYHLAKTGARVTVIDRKEPGQATD--AAAGIVCPWLSQRRNQDWYQLAK 63

Query: 60  YSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNR----------FGVP 109
                +K+L  +L  +     TGY  +       +A K + K++ R           G  
Sbjct: 64  GGARYYKDLIHQLEKD-GESDTGYKRVGAISIHTDASKLD-KMEERAYKRREDAPEIGDI 121

Query: 110 TKLITPEEAKEIVPPL--NVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTE 167
           T+L +  E K++ P L    E          +G+A       +   A EK G        
Sbjct: 122 TRL-SASETKKLFPILADGYESVHISGAARVNGRA----LCRSLLSAAEKRGATVIKGNA 176

Query: 168 VVWIDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEP 227
            +  + G      ++T   +F  D ++    AW + I   +G     ++  K Q++  E 
Sbjct: 177 SLLFENGT--VTGVQTDTKQFAADAVIVTAGAWANEILKPLGIHF-QVSFQKAQIMHFEM 233

Query: 228 LERGQIE-PLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAV 286
            +      P+V PP  +D Y++   ++G ++ G   E  +  DD+  T     EVL  A+
Sbjct: 234 TDADTGSWPVVMPP--SDQYIL-SFDNGRIVAGATHENDAGLDDLRVTAGGQHEVLSKAL 290

Query: 287 KIIPALRHVHVVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHGFMMAPAVAQALA 344
            + P L     V    G    TP   P +G +  V+  Y A G    G  M P +   LA
Sbjct: 291 AVAPGLADAAAVETRVGFRPFTPGFLPVVGAVPNVQGLYAANGLGASGLTMGPFLGAELA 350

Query: 345 ERIVKGRTKVPLDWEWYDP 363
           + ++  +T+  LD   YDP
Sbjct: 351 KLVLGKQTE--LDLSPYDP 367


>pir||B75218 glycerol-3-phosphate dehydrogenase (glpa) PAB0183 - Pyrococcus
           abyssi (strain Orsay) >gi|5457702|emb|CAB49193.1|
           (AJ248283) glycerol-3-phosphate dehydrogenase (glpA)
           [Pyrococcus abyssi]
           Length = 497
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 95/378 (25%), Positives = 160/378 (42%), Gaps = 17/378 (4%)

Query: 2   IGVIGGGIIGVATAYELAKLGE-EVVVFEKRY-FGSGSTFRCASGIRAQFTDEANIKLMK 59
           + +IG GI G + A  L+K    EV + EK    G G +    + I   + D+     M+
Sbjct: 7   VAIIGAGITGASIARVLSKYENLEVHLIEKNPDVGWGVSKANTAIIHGGYDDDPEKYPMR 66

Query: 60  YSI-----ERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPT-KLI 113
                     W E  ++L   I     G L +A  EE+ +  +K ++   + GVP  +++
Sbjct: 67  ARFCVKGNRIWHEWVKQL--EIPHVWNGALVVALEEEDFDELEKLLERGIKNGVPEMRIV 124

Query: 114 TPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDG 173
             EE  ++ P LN    L   W P  G+ +P   + A  +     GVK +  T+V  I  
Sbjct: 125 DKEELFQLEPGLN-RNALGALWVPIVGQIAPIPAVIALVENAVANGVKTHLETKVKGIKV 183

Query: 174 GREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQL-VKTEPLERGQ 232
            R     ++T  G  E D+I+NA   +   I+ M+G D   I P K +  +  E +   +
Sbjct: 184 KRGEVRGLETNDGFIEADIIINAAGLYADEISRMVGLDYFEIRPRKGEYWIFDEGIPGPK 243

Query: 233 IEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKS--DPDDVTPTYDFVKEVLKWAVKIIP 290
                 P   +   V+     G ++ G   +  S  + ++   T + + EV + A K+ P
Sbjct: 244 RVLFPTPTPISKGIVVTTEISGHLMIGPNAKDLSPEEKENTATTREGLDEVWEGAKKLWP 303

Query: 291 AL-RHVHVVRQWAGHYAKTPDNNPAI--GELVEDFYVAIGFSGHGFMMAPAVAQALAERI 347
            L     V+R +AG   +    +  I   E V  F    G    G   APA+A  +AE I
Sbjct: 304 NLPPRSKVIRTFAGLRPEPTGGDFIIRAEEEVWGFINVAGIRSPGLTSAPAIAYYVAELI 363

Query: 348 VKGRTKVPLDWEWYDPYR 365
            +      ++ + ++PYR
Sbjct: 364 ERELDVKLIEKKNWNPYR 381


>sp|P37906|ORDL_ECOLI PROBABLE OXIDOREDUCTASE ORDL >gi|7449558|pir||H64878 probable
           oxidoreductase (EC 1.-.-.-) ordL - Escherichia coli
           >gi|1054921|gb|AAC45300.1| (U38543) oxidoreductase
           [Escherichia coli] >gi|1742131|dbj|BAA14870.1| (D90768)
           Probable oxidoreductase OrdL (EC 1.-.-.-). [Escherichia
           coli] >gi|1787559|gb|AAC74383.1| (AE000228) probable
           oxidoreductase [Escherichia coli K12]
           Length = 426
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 79/367 (21%), Positives = 150/367 (40%), Gaps = 43/367 (11%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63
           V+GGG  G+++A  LA+ G +VVV E    G G++ R    +   ++ + ++    Y ++
Sbjct: 32  VVGGGYTGLSSALHLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRDIDVIEKSYGMD 91

Query: 64  RWKELSEEL--GHNIMFQQT-----------GYLFLATTEEEVEAFKKNIKLQNRFGVPT 110
             + L   +  G  I+ ++            G LF+A  ++++   ++  +   R+G   
Sbjct: 92  TARMLGSMMFEGGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYG--N 149

Query: 111 KLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVW 170
           K +   +A  I   +  + +     +   G   P +       A    G + Y  + V  
Sbjct: 150 KQLELLDANAIRREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQ 209

Query: 171 IDGGREHKWKIKTTKGEFEVDVIVNATNAW-GSRINSMIGKDIVPITPFKHQLVKTEPLE 229
           I         ++T KG+     ++ A NA+ G ++   + K  +P      Q++ TE L 
Sbjct: 210 IQ--HTTPAVVRTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGT---QVITTERLS 264

Query: 230 RGQIEPLVCPPAWNDSYVIQDGE----------DGGVICGTALEYKS-DPDDVTPTYDFV 278
                 L+       +Y ++D            D  ++ G  + Y + DPDDV       
Sbjct: 265 EDLARSLI-----PKNYCVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVE------ 313

Query: 279 KEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPA 338
           + V+   +K  P L+ V +  +W G++  T    P  G L  + Y   G+SGHG      
Sbjct: 314 RLVVPKLLKTFPQLKGVKIDYRWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHL 373

Query: 339 VAQALAE 345
             + +AE
Sbjct: 374 AGRLIAE 380


>dbj|BAB09014.1| (AB007645) contains similarity to unknown
           protein~gene_id:K8K14.1~sp|Q10058 [Arabidopsis thaliana]
           Length = 406
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 99/386 (25%), Positives = 151/386 (38%), Gaps = 46/386 (11%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANI-KLMKYSI 62
           V GGG+IGV TAY LAK G  V + EK      ++ +    +   + D + +  L + S 
Sbjct: 44  VCGGGVIGVCTAYFLAKKGIAVTLVEKSAVACAASGKAGGFLAFDWCDGSPVAHLARASF 103

Query: 63  ERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTK----LITPEEA 118
           +  + L+EEL     +       L+ T  E +     + L +    P K    + T +  
Sbjct: 104 KLHRSLAEELNGVESYGYRALTTLSVTVTESKPGSGGLGLPDWVNGPAKSTSTIGTTQTT 163

Query: 119 KEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVK-FYPYTEVVWIDGGREH 177
            ++ P L   + L+                     A EK GV+      E V ++ GR +
Sbjct: 164 AQVHPQLFTRKLLS--------------------TAREKYGVEVVIGKLEEVRVESGRVN 203

Query: 178 KWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEP-- 235
              ++  +   + DV+V A   W S+   +    I  +   K   +  EP E   I P  
Sbjct: 204 SVVLEGGR-VIDTDVVVLAMGPWSSKFELL--SSIFRVYCTKAHSIVLEPKEPNAITPHA 260

Query: 236 --LVCPPAWN----DSYVIQDGEDGGVICGTAL--EYKSDPDDVTPTYDFVKEVLKWAVK 287
             L   PA      D  V         ICG +   E   D D VT   + + +VLK   K
Sbjct: 261 LFLTYRPAHGGEALDPEVYPRPTGEVYICGMSSQEEVPDDADQVTSNPESI-QVLKRVAK 319

Query: 288 IIPAL---RHVHVVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHGFMMAPAVAQA 342
            + +     +  V  + A     T D  P IGE+  ++  YV  G S  G +  PA   A
Sbjct: 320 TVSSYLNEENALVKAEQACFLPSTEDGVPVIGEIPGIKGCYVGTGHSCWGILNGPATGAA 379

Query: 343 LAERIVKGRTKVPLDWEWYDPYRFER 368
           LAE IV G     +D   + P RF +
Sbjct: 380 LAELIVDG-VATSVDLSRFSPSRFSK 404


>emb|CAC11772.1| (AL445064) glycerol-3-phosphate dehydrogenase related protein
           [Thermoplasma acidophilum]
           Length = 422
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 96/370 (25%), Positives = 153/370 (40%), Gaps = 40/370 (10%)

Query: 2   IGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFR----CASGIRAQFTDEANIKL 57
           I VIG GI G+  AY LA  G +V VFE+    SG++ R      SG R    DE + + 
Sbjct: 8   IAVIGAGINGIFAAYYLAYAGYDVTVFERGDIDSGTSGRFHGMLHSGARYATNDEVSARE 67

Query: 58  MKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEE 117
                 R       +GH  + + TG  FLA  ++E E          R G+    I  EE
Sbjct: 68  CIVENRR----ISNIGHRYV-ENTGGYFLAANDDEAEFGDVLFDACRRAGIDISEIPIEE 122

Query: 118 AKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWID----- 172
                P L   +    A    D     +  + +   A   +G K   Y++V  ID     
Sbjct: 123 FARDNPQL---KNARRAMRVPDKVIRSYEFVVSVAAAAHLMGTKIRTYSDVKKIDIEGNS 179

Query: 173 -GGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERG 231
             G E++   K    +F  D +VNAT  +  +I    G    P+ P    +V  E     
Sbjct: 180 VTGIEYERSGKEISEKF--DAVVNATGPFSGKILERSGLKQTPVMPSAGIMVVLEGRVST 237

Query: 232 QI-----EPL---VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLK 283
            I     EP    +  P W++S +        V+      ++ +P+D+    D + E++ 
Sbjct: 238 AILNRMREPSDADILLPYWSNSIL----GTSAVVVEDPDSFRPEPEDMQMMIDDMSELVP 293

Query: 284 WAVKIIPALRHVHVVR---QWAGHYAKTPDNNPAI--GELVEDFYVAIGFSGHGFMMAPA 338
            AVKI+P  R+ + VR   + AG  A+T   +  I   E ++D  +++   G  F     
Sbjct: 294 -AVKIMPIKRYYYSVRPLIEDAGEDARTASRSFRIVGEEDLDDTLLSV--VGGKFTTGRL 350

Query: 339 VAQALAERIV 348
           V + +A+R++
Sbjct: 351 VGEEIAKRVM 360


>pir||G81179 oxidoreductase, probable NMB0614 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7225844|gb|AAF41041.1| (AE002416) oxidoreductase,
           putative [Neisseria meningitidis MC58]
           Length = 431
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 82/366 (22%), Positives = 151/366 (40%), Gaps = 33/366 (9%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSG----------STFRCASG-IRAQFTDE 52
           +IGGG+ G+ TA  LA+ G E VV E    G G          S + C  G I  Q   E
Sbjct: 37  IIGGGLGGLCTALPLAEQGHETVVLEAARIGFGASGRSGGQVISDYACGMGEIEKQVGLE 96

Query: 53  ANIKLMKYSIERWKELSEELGHNIMF--QQTGYLFLATTEEEVEAFKK-NIKLQNRFGVP 109
                 + S++  + + E +  + +    Q GY  +A   +  E  ++ +   Q  +G  
Sbjct: 97  QAQWFWQQSLQAVELVDERVRKHAVDCDWQRGYATVAVRPQHWEELQQWHEHAQRHYGAS 156

Query: 110 TKLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVV 169
              +   +  E+   L+ + +    ++P  G   P        +A  + G + +  + + 
Sbjct: 157 HYQLW--DKAELKQQLDSDMYQGAQFDPLSGHLHPLTYTLGIARAAAEAGAQIFEQSPMT 214

Query: 170 WIDGGREHKWKIKTTKGEFEVDVIVNATNAWG--SRINSMIGKDIVPITPFKHQLVKTEP 227
            I+   ++ W + T +G  E   +V A N +   + I   + +  + ++ F   ++ TEP
Sbjct: 215 CIEP-HQNGWLVYTPEGSVECKNVVYAVNTYAGLNPIFRPLERKAIAVSTF---IIATEP 270

Query: 228 L---ERGQIEP--LVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVL 282
           L    +G I     VC       Y     +   +  G   E+  +P+ +T   + V++ +
Sbjct: 271 LGARAKGLIRNNMAVCDNRHILDYYRLSADGRLLFGGKDNEFIDNPERMT---ELVRQDM 327

Query: 283 KWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQA 342
              +K+ P L  V +   W G    T +  P  G L  + + A G+SGHG  +      A
Sbjct: 328 ---LKVFPQLADVKIEYSWGGECDITANLVPHFGRLAPNVFYAQGYSGHGMAITGIAGLA 384

Query: 343 LAERIV 348
           +AE I+
Sbjct: 385 VAEAIL 390


>pir||B83078 probable D-amino acid oxidase PA4548 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9950792|gb|AAG07936.1|AE004868_7 (AE004868) probable
           D-amino acid oxidase [Pseudomonas aeruginosa]
           Length = 364
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 86/375 (22%), Positives = 161/375 (42%), Gaps = 53/375 (14%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFT---DEANIKLMKY 60
           V+G G+IG+ TA ELA  G  V + E+   G  +++     +   +      A   L  +
Sbjct: 7   VVGAGVIGLLTARELALAGLRVTLVERGESGREASWAGGGIVSPLYPWRYSPAVTALAHW 66

Query: 61  SIERWKELSEELGHNIMFQQTGY--------LFLATTEEEVEAFKKNIKLQNRFGVPTKL 112
           S + +  L + L       +TG         L+    +++ EA    ++   +   P K 
Sbjct: 67  SQDFYPALGQRL-----LDETGLDPEVHTVGLYWLDLDDQTEA----LQWARKHTRPLKE 117

Query: 113 ITPEEAKEIVPPLNV----EEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEV 168
           +  EEA   VP L        +++G  N  + + +   +L A  +    L  + +  TEV
Sbjct: 118 VPIEEAYAAVPGLGAGFQRAVYMSGVANVRNPRLA--RSLRASLQQFANL--ELHEQTEV 173

Query: 169 V-WIDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEP 227
             W+  G +    + T++GE   D ++ A  AW   +   +G ++ P+ P K Q++  + 
Sbjct: 174 RGWLRDG-DRVVGVATSRGEIRGDKVLLAAGAWSGELLKPLGLEL-PVVPVKGQMILYK- 230

Query: 228 LERGQIEPLVCPPAWNDSYVIQDGE------DGGVICGTALEYKSDPDDVTPTYDFVKEV 281
                     C   +    V+  G       DG ++ G+ LE+     D TPT +  + +
Sbjct: 231 ----------CAADFLPRMVLAKGRYAIPRRDGHILIGSTLEHSGF--DKTPTDEAQESL 278

Query: 282 LKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHGFMMAPAV 339
              A +++P L  +  V  WAG    +P+  P IG +   +  ++  G   +G ++APA 
Sbjct: 279 RASAAELLPELADMQPVAHWAGLRPGSPEGIPYIGPVPGFDGLWLNTGHYRNGLVLAPAS 338

Query: 340 AQALAERIVKGRTKV 354
            + LA+ ++ GR  +
Sbjct: 339 CRLLAD-LMSGREPI 352


>pir||T35488 probable oxidoreductase - Streptomyces coelicolor (fragment)
           >gi|5689917|emb|CAB51955.1| (AL109661) putative
           oxidoreductase [Streptomyces coelicolor A3(2)]
           Length = 375
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 81/355 (22%), Positives = 147/355 (40%), Gaps = 18/355 (5%)

Query: 9   IIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTD-----EANIKLMKYSIE 63
           IIG+ TA+  A+ G    + +      G   + A+G+ A  T+     E  + L   S  
Sbjct: 1   IIGLVTAWRAARRGLVTALVDPE--PGGGAAQVAAGMLAAVTELHYGEETLLALNLASAR 58

Query: 64  RWKELSEEL----GHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAK 119
           R+ E + EL    GH++ +++ G L +A   ++    ++   LQ R G+ ++ ++  E +
Sbjct: 59  RYPEFAAELTELTGHDLGYRRCGTLAVALDADDRAHLRELHALQQRSGLESEWLSGRECR 118

Query: 120 EIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYP-YTEVVWIDGGREHK 178
            + P L       G     D +  P     A   A E  GV F+  + E + +  G    
Sbjct: 119 RLEPML-APGVRGGLRVDGDHQIDPRRLARALVAACEHAGVVFHRVWAERLTVGRGDRAT 177

Query: 179 WKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVK-TEPLERGQIEPLV 237
             +       E   +V A  +   R+  +    + P+ P K Q+++ T P   G +    
Sbjct: 178 GVVGADGTALEAGQVVLAGGSLSGRLGGVPEAVLPPVRPVKGQVLRLTMPRTPGPLLNRT 237

Query: 238 CPPAWNDSYV-IQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296
                  ++V +   E G ++ G   E      D T T   V E+L+ A +++P +  + 
Sbjct: 238 VRAVVRGNHVYLVPRESGELVVGATSEELGW--DTTVTAGGVYELLRDAHELVPGITELP 295

Query: 297 VVRQWAGHYAKTPDNNPAIGELVED-FYVAIGFSGHGFMMAPAVAQALAERIVKG 350
           +    AG    +PDN P +G    D   +A G   +G ++ P     +AE +  G
Sbjct: 296 LTETRAGLRPGSPDNAPLLGPTALDGLLLATGHYRNGVLLTPVTGDVMAEALTGG 350


>sp|P43799|GLPA_HAEIN ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT A (G-3-P
           DEHYDROGENASE) >gi|1074156|pir||E64086
           glycerol-3-phosphate dehydrogenase (EC 1.1.99.5) chain
           A, anaerobic - Haemophilus influenzae (strain Rd KW20)
           >gi|1573687|gb|AAC22345.1| (U32751) anaerobic
           glycerol-3-phosphate dehydrogenase, subunit A (glpA)
           [Haemophilus influenzae Rd]
           Length = 563
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 79/314 (25%), Positives = 134/314 (42%), Gaps = 27/314 (8%)

Query: 4   VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFR----CASGIRAQFTDEANIKLMK 59
           +IGGG  G   A + A  G + ++ E+R   +G+T R      SG R    D+ +    +
Sbjct: 23  IIGGGATGAGIARDCALRGIDCILLERRDIATGATGRNHGLLHSGARYAVNDQES---AE 79

Query: 60  YSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAK 119
             I+  + L +   H +   +T  LF+   E+ ++  K  ++   + G+  + I PE AK
Sbjct: 80  ECIKENRILRKIARHCV--DETEGLFITLPEDSLDYQKTFLESCAKSGIDAQAIDPELAK 137

Query: 120 EIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI--DGGR-- 175
            + P +N +  L GA    DG   PF    +      + G K + Y EV  +  +GG+  
Sbjct: 138 IMEPSVNPD--LVGAVVVPDGSIDPFRLTASNMMDATENGAKMFTYCEVKNLIREGGKVI 195

Query: 176 -----EHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLER 230
                +HK      + +F   ++VNA   WG  I       I         LV    + +
Sbjct: 196 GVNAYDHK---NRRERQFFAPLVVNAGGIWGQGIAEYADLKIKMFPAKGALLVMGHRINK 252

Query: 231 GQIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDP-DDVTPTYDFVKEVLKWAVKII 289
             I     P    D+ ++  G+   VI  T+     D  D++  T + V  + +   K+ 
Sbjct: 253 LVINRCRKPA---DADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDILFREGEKLA 309

Query: 290 PALRHVHVVRQWAG 303
           P+LRH  V+R +AG
Sbjct: 310 PSLRHTRVLRAYAG 323


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.138    0.426 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 157706506
Number of Sequences: 2977
Number of extensions: 7134743
Number of successful extensions: 16181
Number of sequences better than 1.0e-10: 51
Number of HSP's better than  0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 16044
Number of HSP's gapped (non-prelim): 57
length of query: 379
length of database: 189,106,746
effective HSP length: 53
effective length of query: 326
effective length of database: 157,386,935
effective search space: 51308140810
effective search space used: 51308140810
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)