BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0214 (soxB) DE:sarcosine oxidase, subunit beta (soxB) (379 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||F75144 sarcosine oxidase, chain beta (soxb) PAB0214 - Pyroc... 791 0.0 pir||B71184 probable sarcosine oxidase - Pyrococcus horikoshii >... 705 0.0 pir||F71008 probable sarcosine oxidase - Pyrococcus horikoshii >... 420 e-116 pir||G75122 sarcosine oxidase, chain beta (soxb) PAB1843 - Pyroc... 414 e-114 gi|11497890 sarcosine oxidase, subunit beta (soxB) [Archaeoglobu... 190 3e-47 sp|Q63342|M2GD_RAT DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL ... 158 1e-37 gi|11417071 dimethylglycine dehydrogenase precursor [Homo sapiens] 155 8e-37 gi|7019365 dimethylglycine dehydrogenase precursor [Homo sapiens... 155 8e-37 gb|AAD03414.1| (AF067650) sarcosine dehydrogenase [Rattus norveg... 129 4e-29 gb|AAD32214.1| (AF140745) sarcosine dehydrogenase [Homo sapiens]... 129 4e-29 gb|AAD53398.2|AF095735_1 (AF095735) sarcosine dehydrogenase [Hom... 129 4e-29 gb|AAD13137.1| (AF047190) dimethylglycine dehydrogenase-like pro... 129 6e-29 gi|8923708 hypothetical protein [Homo sapiens] >gi|11437505|ref|... 124 1e-27 sp|P40875|SAOX_CORS1 SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE O... 123 3e-27 gb|AAC48785.1| (AF026954) pyruvate dehydrogenase phosphatase reg... 118 8e-26 gb|AAK40533.1| Sarcosine oxidase, subunit beta (soxB-like) [Sulf... 118 1e-25 gb|AAD13136.1| (AF047004) dimethylglycine dehydrogenase-like pro... 115 9e-25 gb|AAF57379.1| (AE003789) CG3270 gene product [Drosophila melano... 112 6e-24 gb|AAF57796.1| (AE003802) CG6385 gene product [Drosophila melano... 111 1e-23 pir||E72254 conserved hypothetical protein - Thermotoga maritima... 108 1e-22 gi|10955084 agaE [Agrobacterium tumefaciens] >gi|11352852|pir||T... 106 6e-22 pir||H82968 sarcosine oxidase beta subunit PA5416 [imported] - P... 105 8e-22 dbj|BAB05153.1| (AP001512) glycine oxidase (sarcosine oxidase) [... 103 3e-21 sp|O31616|GLOX_BACSU GLYCINE OXIDASE >gi|7475812|pir||B69845 sar... 102 7e-21 gb|AAD53399.2|AF095736_1 (AF095736) unknown [Homo sapiens] 102 7e-21 gi|6005868 sarcosine dehydrogenase; dimethylglycine dehydrogenas... 101 1e-20 gb|AAB03674.1| (U62481) dimethylglycine dehydrogenase-like prote... 96 7e-19 dbj|BAB05760.1| (AP001514) unknown conserved protein [Bacillus h... 93 4e-18 sp|O87388|SAOX_RHIME SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE O... 92 8e-18 pir||F83487 hypothetical protein PA1267 [imported] - Pseudomonas... 92 1e-17 pir||H83370 hydrogen cyanide synthase HcnC PA2195 [imported] - P... 91 2e-17 gb|AAK42656.1| Glycerol-3-phosphate dehydrogenase chain A (glpA)... 90 5e-17 sp|Q52671|SAOX_RHOCA SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE O... 87 4e-16 pir||E82983 probable oxidoreductase PA5309 [imported] - Pseudomo... 83 7e-15 gb|AAC38596.1| (AF053760) hydrogen cyanide synthase HcnC [Pseudo... 83 7e-15 pir||H70361 conserved hypothetical protein aq_707 - Aquifex aeol... 82 1e-14 pir||C83407 hypothetical protein PA1918 [imported] - Pseudomonas... 80 3e-14 pir||G83298 conserved hypothetical protein PA2776 [imported] - P... 79 7e-14 gb|AAG20146.1| (AE005092) glycerol-3-phosphate dehydrogenase cha... 79 7e-14 pir||S76505 hypothetical protein - Synechocystis sp. (strain PCC... 79 1e-13 gb|AAA96395.1| (U38892) N-terminal and C-terminal ends are simil... 79 1e-13 sp|P44732|ORDL_HAEIN PROBABLE OXIDOREDUCTASE ORDL >gi|1073832|pi... 77 4e-13 sp|O32159|YURR_BACSU HYPOTHETICAL 39.4 KD OXIDOREDUCTASE IN HOM-... 76 6e-13 pir||B75218 glycerol-3-phosphate dehydrogenase (glpa) PAB0183 - ... 75 1e-12 sp|P37906|ORDL_ECOLI PROBABLE OXIDOREDUCTASE ORDL >gi|7449558|pi... 74 2e-12 dbj|BAB09014.1| (AB007645) contains similarity to unknown protei... 73 4e-12 emb|CAC11772.1| (AL445064) glycerol-3-phosphate dehydrogenase re... 71 2e-11 pir||G81179 oxidoreductase, probable NMB0614 [imported] - Neisse... 71 2e-11 pir||B83078 probable D-amino acid oxidase PA4548 [imported] - Ps... 71 2e-11 pir||T35488 probable oxidoreductase - Streptomyces coelicolor (f... 70 4e-11 sp|P43799|GLPA_HAEIN ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENAS... 69 6e-11 >pir||F75144 sarcosine oxidase, chain beta (soxb) PAB0214 - Pyrococcus abyssi (strain Orsay) >gi|5457747|emb|CAB49237.1| (AJ248284) sarcosine oxidase, subunit beta (soxB) [Pyrococcus abyssi] Length = 379 Score = 791 bits (2020), Expect = 0.0 Identities = 379/379 (100%), Positives = 379/379 (100%) Query: 1 MIGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY 60 MIGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY Sbjct: 1 MIGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY 60 Query: 61 SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKE 120 SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKE Sbjct: 61 SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKE 120 Query: 121 IVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK 180 IVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK Sbjct: 121 IVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK 180 Query: 181 IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240 IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP Sbjct: 181 IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240 Query: 241 AWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQ 300 AWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQ Sbjct: 241 AWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQ 300 Query: 301 WAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEW 360 WAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEW Sbjct: 301 WAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEW 360 Query: 361 YDPYRFERGELRTSAFQIG 379 YDPYRFERGELRTSAFQIG Sbjct: 361 YDPYRFERGELRTSAFQIG 379 >pir||B71184 probable sarcosine oxidase - Pyrococcus horikoshii >gi|3258182|dbj|BAA30865.1| (AP000007) 377aa long hypothetical sarcosine oxidase [Pyrococcus horikoshii] Length = 377 Score = 705 bits (1801), Expect = 0.0 Identities = 329/379 (86%), Positives = 361/379 (94%), Gaps = 2/379 (0%) Query: 1 MIGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY 60 MIG+IGGGIIG+ATAYELAKLGEEV+VFEKRYFGSGSTFRCASGIRAQFTDEANI+LMKY Sbjct: 1 MIGIIGGGIIGIATAYELAKLGEEVIVFEKRYFGSGSTFRCASGIRAQFTDEANIRLMKY 60 Query: 61 SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKE 120 SI++WK+LSEEL + +MFQQTGYLFLAT+EEEV+AFK+NIKLQN+FGVPTKLITPEEAKE Sbjct: 61 SIDKWKKLSEELEYEVMFQQTGYLFLATSEEEVKAFKRNIKLQNKFGVPTKLITPEEAKE 120 Query: 121 IVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK 180 IVPPLN + FLAGAWNPEDGKASPFHTLY YK+AGEKLGV+FYPYTEV+ I + KW Sbjct: 121 IVPPLNADAFLAGAWNPEDGKASPFHTLYGYKRAGEKLGVRFYPYTEVIGIK--KNDKWI 178 Query: 181 IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240 IKTT+GEF VDVIVNATNAWG RINSMIGKDIVPI PFKHQLVKTEP+ERGQIEPLVCPP Sbjct: 179 IKTTRGEFRVDVIVNATNAWGRRINSMIGKDIVPIKPFKHQLVKTEPIERGQIEPLVCPP 238 Query: 241 AWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQ 300 AW+DSYVIQDGEDGGVICGTALEYK +PDDVTPTYDFVKE LKWAVKI+PAL+HVH++RQ Sbjct: 239 AWSDSYVIQDGEDGGVICGTALEYKGNPDDVTPTYDFVKEALKWAVKIVPALKHVHIIRQ 298 Query: 301 WAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEW 360 WAG+YAKTPDNNPAIGEL EDFYVAIGFSGHGFMMAPAV+QALAE+IVKG+TKVPLDWEW Sbjct: 299 WAGYYAKTPDNNPAIGELEEDFYVAIGFSGHGFMMAPAVSQALAEKIVKGKTKVPLDWEW 358 Query: 361 YDPYRFERGELRTSAFQIG 379 +DPYRFERGELR+SAFQIG Sbjct: 359 FDPYRFERGELRSSAFQIG 377 >pir||F71008 probable sarcosine oxidase - Pyrococcus horikoshii >gi|3257787|dbj|BAA30470.1| (AP000006) 382aa long hypothetical sarcosine oxidase [Pyrococcus horikoshii] Length = 382 Score = 420 bits (1067), Expect = e-116 Identities = 213/382 (55%), Positives = 277/382 (71%), Gaps = 11/382 (2%) Query: 2 IGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61 I VIGGGI+GV A+ELAK GEEV V EKR+ GSGSTFRC +GIR QF DEAN+++MK S Sbjct: 8 IVVIGGGIVGVTIAHELAKRGEEVTVIEKRFIGSGSTFRCGTGIRQQFNDEANVRVMKRS 67 Query: 62 IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 +E WK+ SEE G + F+QTGYLFL +EEV+ FK+NI++QN+FGVPTKLITPEEAKEI Sbjct: 68 VELWKKYSEEYGFS--FKQTGYLFLLYDDEEVKTFKRNIEIQNKFGVPTKLITPEEAKEI 125 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181 VP L++ E +A +WNP DGKA PF A+ ++ G K YTEV + Sbjct: 126 VPLLDISEVIAASWNPTDGKADPFEATTAFAVKAKEYGAKLLEYTEVKGFLIENNEIKGV 185 Query: 182 KTTKGEFEVDVIVNATNAWGSRINSMIG-KDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240 KT KG + ++VNATNAW + IN+M G K +PI P+KHQ V T+P++RG I P+V Sbjct: 186 KTNKGIIKTGIVVNATNAWANLINAMAGIKTKIPIEPYKHQAVITQPIKRGTINPMVISF 245 Query: 241 AWNDSYVIQDGEDGGVICGTALEYKSDPD-DVTPTYDFVKEVLKWAVKIIPALRHVHVVR 299 + +Y+ Q GG+I G + Y+ P D+TPTY+F++EV + KIIPAL+++ ++R Sbjct: 246 KYGHAYLTQTFH-GGIIGG--IGYEIGPTYDLTPTYEFLREVSYYFTKIIPALKNLLILR 302 Query: 300 QWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLD 357 WAG+YAKTPD+NPAIG + E D+Y+A GFSGHGFMMAPAV + +AE I KG+TK+P+ Sbjct: 303 TWAGYYAKTPDSNPAIGRIEELNDYYIAAGFSGHGFMMAPAVGEMVAELITKGKTKLPV- 361 Query: 358 WEWYDPYRFERGELRTSAFQIG 379 EWYDPYRFERGELRT+A Q+G Sbjct: 362 -EWYDPYRFERGELRTAALQMG 382 >pir||G75122 sarcosine oxidase, chain beta (soxb) PAB1843 - Pyrococcus abyssi (strain Orsay) >gi|5458207|emb|CAB49696.1| (AJ248285) sarcosine oxidase, subunit beta (soxB) [Pyrococcus abyssi] Length = 382 Score = 414 bits (1052), Expect = e-114 Identities = 209/380 (55%), Positives = 275/380 (72%), Gaps = 11/380 (2%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63 VIGGGI+GV+ A+ELAK G +V V EKR+ GSGSTFRC +GIR QF DEAN+++MK S+E Sbjct: 10 VIGGGIVGVSIAHELAKRGVDVTVLEKRFIGSGSTFRCGTGIRQQFNDEANVRVMKRSVE 69 Query: 64 RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVP 123 WK+ SEE +N F+QTGYLFL EEEVE FK+NI++QN+FGVPT+LITPEEAKEIVP Sbjct: 70 LWKKYSEE--YNFSFKQTGYLFLLYDEEEVETFKRNIEIQNKFGVPTRLITPEEAKEIVP 127 Query: 124 PLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKIKT 183 L++ E +A +WNP DGKA PF A+ + G K YTEV +KT Sbjct: 128 LLDISEVIAASWNPTDGKADPFEATTAFAIKAREYGAKLLEYTEVKGFIIENGEIKGVKT 187 Query: 184 TKGEFEVDVIVNATNAWGSRINSMIG-KDIVPITPFKHQLVKTEPLERGQIEPLVCPPAW 242 +G + ++VNATNAW IN+M G K +PI P+KHQ V T+P++RG I P+V + Sbjct: 188 NRGTIKTGIVVNATNAWAKLINAMAGIKVKIPIEPYKHQAVITQPIKRGTINPMVISFKY 247 Query: 243 NDSYVIQDGEDGGVICGTALEYKSDPD-DVTPTYDFVKEVLKWAVKIIPALRHVHVVRQW 301 +Y+ Q GG+I G + Y+ P D+TPTY+F++EV + KIIPAL+++ V+R W Sbjct: 248 GHAYLTQTFH-GGIIGG--IGYEIGPTYDLTPTYEFLREVSYYFTKIIPALKNLLVLRTW 304 Query: 302 AGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWE 359 AG+YAKTPD+NPAIG++ E D+Y+A GFSGHGFMMAPAV + +A+ I KG++K+P+ E Sbjct: 305 AGYYAKTPDSNPAIGKIEELSDYYIAAGFSGHGFMMAPAVGEMIADLITKGKSKLPV--E 362 Query: 360 WYDPYRFERGELRTSAFQIG 379 WYDPYRFERGELRT+A Q+G Sbjct: 363 WYDPYRFERGELRTAALQMG 382 >gi|11497890 sarcosine oxidase, subunit beta (soxB) [Archaeoglobus fulgidus] >gi|7483942|pir||B69284 sarcosine oxidase, subunit beta (soxB) homolog - Archaeoglobus fulgidus >gi|2650362|gb|AAB90958.1| (AE001086) sarcosine oxidase, subunit beta (soxB) [Archaeoglobus fulgidus] Length = 354 Score = 190 bits (477), Expect = 3e-47 Identities = 117/356 (32%), Positives = 192/356 (53%), Gaps = 13/356 (3%) Query: 2 IGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61 + VIGGG+ G++ AY LAK G +V VFE++Y G++ R + G+ AQFT+EA IKL K + Sbjct: 3 VAVIGGGVAGLSAAYFLAKAGADVKVFEQKYLLYGASGRNSGGLTAQFTNEAMIKLAKRT 62 Query: 62 IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 +E + EL E+G N + ++ GY+ +A EE + ++ ++ Q + GV K++ PE KE+ Sbjct: 63 LELYDELQSEVGFNFLLRRDGYVKIAGKGEEAK-LREEVEFQRKAGVKVKMVEPEFVKEL 121 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEV-VWIDGGREHKWK 180 P +N F A ++ + G P+ ++ K +LGV+ Y YT V + G + Sbjct: 122 FPDINTSAFTAASYFADGGVVFPWPVVWGLAKGCRELGVEIYDYTPASVEVKG---NDLT 178 Query: 181 IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPP 240 +K + ++VD I+NA AW + I+ G ++ F+ ++ TE L +P + P Sbjct: 179 VKASGESYKVDYIINAAGAWSNEISQQAGVEL-NNKVFREEICVTESL-----KPYLDPY 232 Query: 241 AWNDSYVIQDGED-GGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVR 299 + S + + G I G L ++D + + DF+ K +++P LR + V+R Sbjct: 233 IMDISTGVYFSQSMRGEIVGGILGSETDRLETKASLDFLTTYAKRVTELVPKLRGMAVLR 292 Query: 300 QWAGHYAKTPDNNPAIGEL-VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKV 354 QWAG Y + P IG+ V F GF HG +A A + +AE IVKGR+ + Sbjct: 293 QWAGLYDAGRNGMPVIGQTKVRGFIQLNGFGRHGMSLALAAGEGVAELIVKGRSSI 348 >sp|Q63342|M2GD_RAT DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR (ME2GLYDH) >gi|111583|pir||S16133 dimethylglycine dehydrogenase (EC 1.5.99.2) - rat >gi|56689|emb|CAA39468.1| (X55995) dimethylglycine dehydrogenase [Rattus norvegicus] Length = 857 Score = 158 bits (395), Expect = 1e-37 Identities = 122/391 (31%), Positives = 186/391 (47%), Gaps = 40/391 (10%) Query: 4 VIGGGIIGVATAYELAKLG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY-S 61 +IGGG +GV+ AY LAK G +VV+ EK +GST+ A+G+ F N+K + Y S Sbjct: 47 IIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH-AAGLTTYFHPGINLKKIHYDS 105 Query: 62 IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 I+ ++ L EE G + F Q G + LATT E V+ FK + N +I PE+ E+ Sbjct: 106 IKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHEL 165 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181 P LN+++ LAG +NP DG P+ A K GV V + + W + Sbjct: 166 FPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDV 225 Query: 182 KTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTE--PLERGQIEPLVCP 239 +T +G + IVNA W + MIG D P+ P +HQ V T P + L Sbjct: 226 ETPQGSVRANRIVNAAGFWAREVGKMIGLD-HPLIPVQHQYVVTSTIPEVKALKRELPVL 284 Query: 240 PAWNDSYVIQDGEDG---------------------GVICGTALE-YKSDPDDVTPTYDF 277 SY ++ DG GV G E ++SD D +T Sbjct: 285 RDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRIT----- 339 Query: 278 VKEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIG--ELVEDFYVAIGFSGHGFMM 335 E ++ A++++P L+ ++ G +PD P +G + V +++VAIGF G+G + Sbjct: 340 --EHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYGIIH 396 Query: 336 APAVAQALAERIVKGRTKVPLDWEWYDPYRF 366 A V + L++ I+ G + P D DP R+ Sbjct: 397 AGGVGKYLSDWILHG--EPPFDLIELDPNRY 425 >gi|11417071 dimethylglycine dehydrogenase precursor [Homo sapiens] Length = 866 Score = 155 bits (388), Expect = 8e-37 Identities = 116/384 (30%), Positives = 183/384 (47%), Gaps = 26/384 (6%) Query: 4 VIGGGIIGVATAYELAKLG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY-S 61 +IGGG +GV+ AY LAK G ++VV+ EK +GST+ A+G+ F N+K + Y S Sbjct: 54 IIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH-AAGLTTYFHPGINLKKIHYDS 112 Query: 62 IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 I+ +++L EE G + F Q G + LATT V+ FK + LI PE+ +E+ Sbjct: 113 IKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEM 172 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181 P LN+ + LAG +NP DG P+ A K G V + + W + Sbjct: 173 FPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDV 232 Query: 182 KTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPPA 241 +T +G + IVNA W + MIG + P+ P +HQ V T + + P Sbjct: 233 ETPQGSMRANRIVNAAGFWAREVGKMIGLE-HPLIPVQHQYVVTSTISEVKALKRELPVL 291 Query: 242 --WNDSYVIQDGEDGGVICGTALEYKSDPDD------VTPTY---------DFVKEVLKW 284 SY ++ DG + + K D V P + D + E +K Sbjct: 292 RDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKA 351 Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIG--ELVEDFYVAIGFSGHGFMMAPAVAQA 342 A++++P L+ ++ G +PD P +G + V +++VAIGF G+G + A V + Sbjct: 352 AMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKY 410 Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366 L++ I+ G + P D DP R+ Sbjct: 411 LSDWILHG--EPPFDLIELDPNRY 432 >gi|7019365 dimethylglycine dehydrogenase precursor [Homo sapiens] >gi|11133608|sp|Q9UI17|M2GD_HUMAN DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR (ME2GLYDH) >gi|6650622|gb|AAF21941.1|AF111858_1 (AF111858) dimethylglycine dehydrogenase precursor [Homo sapiens] Length = 866 Score = 155 bits (388), Expect = 8e-37 Identities = 116/384 (30%), Positives = 183/384 (47%), Gaps = 26/384 (6%) Query: 4 VIGGGIIGVATAYELAKLG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY-S 61 +IGGG +GV+ AY LAK G ++VV+ EK +GST+ A+G+ F N+K + Y S Sbjct: 54 IIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH-AAGLTTYFHPGINLKKIHYDS 112 Query: 62 IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 I+ +++L EE G + F Q G + LATT V+ FK + LI PE+ +E+ Sbjct: 113 IKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEM 172 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181 P LN+ + LAG +NP DG P+ A K G V + + W + Sbjct: 173 FPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDV 232 Query: 182 KTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPPA 241 +T +G + IVNA W + MIG + P+ P +HQ V T + + P Sbjct: 233 ETPQGSMRANRIVNAAGFWAREVGKMIGLE-HPLIPVQHQYVVTSTISEVKALKRELPVL 291 Query: 242 --WNDSYVIQDGEDGGVICGTALEYKSDPDD------VTPTY---------DFVKEVLKW 284 SY ++ DG + + K D V P + D + E +K Sbjct: 292 RDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKA 351 Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIG--ELVEDFYVAIGFSGHGFMMAPAVAQA 342 A++++P L+ ++ G +PD P +G + V +++VAIGF G+G + A V + Sbjct: 352 AMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKY 410 Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366 L++ I+ G + P D DP R+ Sbjct: 411 LSDWILHG--EPPFDLIELDPNRY 432 >gb|AAD03414.1| (AF067650) sarcosine dehydrogenase [Rattus norvegicus] Length = 919 Score = 129 bits (322), Expect = 4e-29 Identities = 106/384 (27%), Positives = 173/384 (44%), Gaps = 30/384 (7%) Query: 4 VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 VIGGG +G T Y LAKLG VV+ E+ SG+T+ A + + ++L+ ++ Sbjct: 72 VIGGGSLGCQTLYHLAKLGVGGVVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 131 Query: 63 ERWK-ELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 + +L EE G + + Q G LF+A+ ++ ++ +K+ + L +G+ + +++P E K++ Sbjct: 132 QVVSHDLEEETGLHTGWIQNGGLFIASNQQRLDEYKRLMSLGKAYGIESHVLSPAETKDL 191 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI-----DGGRE 176 P +NV++ + P DG P T +A G + V I D G Sbjct: 192 YPLMNVDDLYGTLYVPRDGTMDPAGTCTTLTRAAVARGAQVIENCAVTGIRVRTDDFGVR 251 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 ++T G + +VN W S + M G VP+ H V TE +E Q P Sbjct: 252 RVTAVETQHGSIQTPCVVNCAGVWASSVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 310 Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284 V +D+ V + + G Y+++P D+V+ + F L W Sbjct: 311 VRD---HDASVYLRLQGDALSVG---GYEANPIFWDEVSDKFAFGLFDLDWDVFTQHIEG 364 Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQA 342 A+ +P L + G + TPD+ P +GE E F++ GF+ G M+ Q Sbjct: 365 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQE 424 Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366 LA IV GR + D YD RF Sbjct: 425 LAHWIVHGRPE--KDMYSYDIRRF 446 >gb|AAD32214.1| (AF140745) sarcosine dehydrogenase [Homo sapiens] >gi|5453465|gb|AAD43585.1|AF162428_1 (AF162428) sarcosine dehydrogenase [Homo sapiens] Length = 918 Score = 129 bits (322), Expect = 4e-29 Identities = 107/384 (27%), Positives = 174/384 (44%), Gaps = 30/384 (7%) Query: 4 VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 VIGGG +G T Y LAKLG V+ E+ SG+T+ A + + ++L+ ++ Sbjct: 71 VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130 Query: 63 ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 +EL EE G + + Q G LF+A+ + ++ +K+ + L +GV + +++P E K + Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176 P +NV++ + P DG P T +A G ++ P T + VW D G Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 ++T G + +VN W S + M G VP+ H V TE +E Q P Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 309 Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284 V +D+ V + + G Y+++P ++V+ + F L W Sbjct: 310 VRD---HDASVYLRLQGDALSVG---GYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEG 363 Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQA 342 A+ +P L + G + TPD+ P +GE E F++ GF+ G M+ Q Sbjct: 364 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQE 423 Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366 LA I+ GR + D YD RF Sbjct: 424 LAHWIIHGRPE--KDMHGYDIRRF 445 >gb|AAD53398.2|AF095735_1 (AF095735) sarcosine dehydrogenase [Homo sapiens] Length = 918 Score = 129 bits (322), Expect = 4e-29 Identities = 107/384 (27%), Positives = 174/384 (44%), Gaps = 30/384 (7%) Query: 4 VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 VIGGG +G T Y LAKLG V+ E+ SG+T+ A + + ++L+ ++ Sbjct: 71 VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130 Query: 63 ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 +EL EE G + + Q G LF+A+ + ++ +K+ + L +GV + +++P E K + Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176 P +NV++ + P DG P T +A G ++ P T + VW D G Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 ++T G + +VN W S + M G VP+ H V TE +E Q P Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 309 Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284 V +D+ V + + G Y+++P ++V+ + F L W Sbjct: 310 VRD---HDASVYLRLQGDALSVG---GYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEG 363 Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQA 342 A+ +P L + G + TPD+ P +GE E F++ GF+ G M+ Q Sbjct: 364 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQE 423 Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366 LA I+ GR + D YD RF Sbjct: 424 LAHWIIHGRPE--KDMHGYDIRRF 445 >gb|AAD13137.1| (AF047190) dimethylglycine dehydrogenase-like protein isoform 2; putative sarcosine dehydrogenase [Homo sapiens] >gi|4454259|emb|CAA11257.1| (AJ223317) sarcosine dehydrogenase [Homo sapiens] Length = 475 Score = 129 bits (321), Expect = 6e-29 Identities = 107/384 (27%), Positives = 174/384 (44%), Gaps = 30/384 (7%) Query: 4 VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 VIGGG +G T Y LAKLG V+ E+ SG+T+ A + + ++L+ ++ Sbjct: 71 VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130 Query: 63 ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 +EL EE G + + Q G LF+A+ + ++ +K+ + L +GV + +++P E K + Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176 P +NV++ + P DG P T +A G ++ P T + VW D G Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 ++T G + +VN W S + M G VP+ H V TE +E Q P Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 309 Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284 V +D+ V + + G Y+++P ++V+ + F L W Sbjct: 310 VRD---HDASVYLRLQGDALSVG---GYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEG 363 Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHGFMMAPAVAQA 342 A+ +P L + G + TPD+ P +GE E F++ GF+ G M+ Q Sbjct: 364 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSVGMMLGGGCGQE 423 Query: 343 LAERIVKGRTKVPLDWEWYDPYRF 366 LA I+ GR + D YD RF Sbjct: 424 LAHWIIHGRPE--KDMHGYDIRRF 445 >gi|8923708 hypothetical protein [Homo sapiens] >gi|11437505|ref|XP_006258.1| hypothetical protein [Homo sapiens] >gi|6048970|gb|AAF02421.1|AF103801_1 (AF103801) unknown [Homo sapiens] Length = 486 Score = 124 bits (309), Expect = 1e-27 Identities = 105/396 (26%), Positives = 177/396 (44%), Gaps = 51/396 (12%) Query: 4 VIGGGIIGVATAYELAKLGEE-----VVVFEKRY-FGSGSTFRCASGIRAQFTDEANIKL 57 ++GGG++G++ AY L KL V+V E+ + + ST GI QF+ NI+L Sbjct: 68 IVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLSVGGICQQFSLPENIQL 127 Query: 58 MKYSIERWKELSEELGH------NIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTK 111 +S + ++E L ++ F +GYL LA+ E++ A + N+K+Q + G Sbjct: 128 SLFSASFLRNINEYLAVVDAPPLDLRFNPSGYLLLAS-EKDAAAMESNVKVQRQEGAKVS 186 Query: 112 LITPEEAKEIVPPLNVEEFLAGAWNPED-GKASPFHTLYAYKKAGEKLGVKFYPYTEVVW 170 L++P++ + P +N E ++ ED G P+ L ++ + LGV F + Sbjct: 187 LMSPDQLRNKFPWINTEGVALASYGMEDEGWFDPWCLLQGLRRKVQSLGVLFCQGEVTRF 246 Query: 171 IDGG--------------REHKWKIKTTKG----EFEVDVIVNATNAWGSRINSMIGKDI 212 + R H+ +K + E +++NA AW ++I ++ G Sbjct: 247 VSSSQRMLTTDDKAVVLKRIHEVHVKMDRSLEYQPVECAIVINAAGAWSAQIAALAGVGE 306 Query: 213 VPITPFKHQLVKTEPLER-----------GQIEPLVCPPAWNDSYVIQDGEDGGVICGTA 261 P + + EP +R G PLV + +Y ++G + G + Sbjct: 307 GPPGTLQGTKLPVEPRKRYVYVWHCPQGPGLETPLVADTS--GAYFRREGLGSNYLGGRS 364 Query: 262 LEYKSDPDDVTPTYD---FVKEVLKWAVKIIPALRHVHVVRQWAGHYA-KTPDNNPAIGE 317 + +PD D F +V +PA + V WAG+Y T D N +G Sbjct: 365 PTEQEEPDPANLEVDHDFFQDKVWPHLALRVPAFETLKVQSAWAGYYDYNTFDQNGVVGP 424 Query: 318 --LVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGR 351 LV + Y A GFSGHG AP + +A+AE ++KGR Sbjct: 425 HPLVVNMYFATGFSGHGLQQAPGIGRAVAEMVLKGR 460 >sp|P40875|SAOX_CORS1 SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE OXIDASE SUBUNIT B) >gi|2127436|pir||I40887 sarcosine oxidase (EC 1.5.3.1) beta chain [validated] - Corynebacterium sp >gi|927589|gb|AAC43459.1| (U23955) sarcosine oxidase beta subunit [Corynebacterium sp.] Length = 405 Score = 123 bits (306), Expect = 3e-27 Identities = 100/379 (26%), Positives = 165/379 (43%), Gaps = 21/379 (5%) Query: 4 VIGGGIIGVATAYELAKLG--EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61 ++GGG G+ATAY LAK V V EK + G+ R + IR+ + + + + + S Sbjct: 26 IVGGGGHGLATAYYLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLWDESAGIYEKS 85 Query: 62 IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 ++ W++L EEL ++ +F Q G L LA T +V + ++ GV + +TPE+ KE+ Sbjct: 86 LKLWEQLPEELDYDFLFSQRGVLNLAHTLGDVRESVRRVEANKFNGVDAEWLTPEQVKEV 145 Query: 122 VPPLNVEE-----FLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176 P +N+ + + + P G A H +A+ + ++GV EV E Sbjct: 146 CPIINIGDDIRYPVMGATYQPRAGIAKHDHVAWAFARKANEMGVDIIQNCEVTGFLKDGE 205 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 +KTT+G + A S + + G ++ PI Q + +E E + P Sbjct: 206 KVTGVKTTRGTIHAGKVALAGAGHSSVLAELAGFEL-PIQSHPLQALVSELFE--PVHPT 262 Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296 V YV Q G ++ G ++ + + ++E + AV++ P H Sbjct: 263 VVMSNHIHVYVSQ-AHKGELVMGAGIDSYNGYGQ-RGAFHVIEEQMAAAVELFPIFARAH 320 Query: 297 VVRQWAGHYAKTPDNNPAIGEL-VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRT--- 352 V+R W G T D +P I + +++ YV G+ GF P LA I Sbjct: 321 VLRTWGGIVDTTMDASPIISKTPIQNLYVNCGWGTGGFKGTPGAGFTLAHTIANDEAHAL 380 Query: 353 KVPLDWEWYDPYRFERGEL 371 P E RFE G L Sbjct: 381 NAPFSLE-----RFETGHL 394 >gb|AAC48785.1| (AF026954) pyruvate dehydrogenase phosphatase regulatory subunit precursor; PDPr [Bos taurus] Length = 878 Score = 118 bits (294), Expect = 8e-26 Identities = 92/367 (25%), Positives = 166/367 (45%), Gaps = 27/367 (7%) Query: 4 VIGGGIIGVATAYELAKLG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 V GGGI+G + AY L+K+G ++VV+ E+ +GST CA + K+ YS Sbjct: 46 VCGGGIMGTSVAYHLSKMGWKDVVLLEQGRLAAGSTRFCAGILSTARHLAIEQKMADYSN 105 Query: 63 ERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIV 122 + + +L +E G + +TG +FLA T++ + + K+ N G+P ++I+P++ E+ Sbjct: 106 KLYHQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINSRLNVIGIPCEIISPKKVAELH 165 Query: 123 PPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKIK 182 P LNV + + PED S A A + GV+ Y T ++ + + ++ Sbjct: 166 PLLNVHDLVGAMHVPEDAVVSSADVALALASAASQSGVQIYDRTSILHVMVKKGQVAGVE 225 Query: 183 TTKGEFEVDVIVNATNAWGSRINSMIGKDI-VPITPFKHQLVKTEPLERGQIEPLVCPPA 241 T KG+ + VN W + + + +P+ +H + T P E PL P+ Sbjct: 226 TDKGQIQCQYFVNCAGQWAYELGLCSEEPVSIPLHACEHFYLLTRPWE----TPL---PS 278 Query: 242 WNDSYVIQDGE------DGGVICG----------TALEYKSDPDDVTPTYDFVKEVLKWA 285 + V DG GG++ G T + + + ++ +D + +L Sbjct: 279 STPTVVDADGRIYIRNWQGGILSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSL 338 Query: 286 VKIIPALRHVHVVRQWAGHYAKTPDNNPAIGE--LVEDFYVAIGFSGHGFMMAPAVAQAL 343 ++ +P L + +V+ TPD +GE V ++V +G + G + L Sbjct: 339 LRRMPQLETLEIVKLVNCPETFTPDMRCIMGESPSVRGYFVLVGMNSAGLSFGGGAGKYL 398 Query: 344 AERIVKG 350 AE +V G Sbjct: 399 AEWMVYG 405 >gb|AAK40533.1| Sarcosine oxidase, subunit beta (soxB-like) [Sulfolobus solfataricus] Length = 372 Score = 118 bits (292), Expect = 1e-25 Identities = 104/379 (27%), Positives = 178/379 (46%), Gaps = 22/379 (5%) Query: 1 MIGVIGGGIIGVATAYELAKLG---EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKL 57 MI ++G G G++ AY L K G +++ + E + G GS+ R A+ R F + N++ Sbjct: 1 MIIIVGAGSHGLSLAYHLVKKGYSKKDITLVEWKRIGYGSSSRNAARYRYHFYSKENVEY 60 Query: 58 MKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEE 117 +I K+ S+EL +N + +TGYL++ E+E FKK + + + K I E Sbjct: 61 AINAISYLKKQSKELEYNSLLLRTGYLWVINGEQEYSLFKKLDSFWSSYNIGGKFI---E 117 Query: 118 AKEIVPPLNVEE--FLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGR 175 K+ + E +LA P+DG + LY+Y + + Y + D + Sbjct: 118 CKDNYAYIKFEGQCYLA----PQDGAFHHDYILYSYYYSIKDKVSTIYDKVVSLIKDDSK 173 Query: 176 EHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEP 235 K+ + K + VIV A AW + S IG + VPI P K ++ TEPL R +EP Sbjct: 174 IKGVKLSSGKELYGDKVIVTA-GAWSGEVLSSIGIE-VPIFPEKKEIYITEPL-RYFLEP 230 Query: 236 LVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHV 295 L+ G +I G + + ++ T + + LK ++I + + Sbjct: 231 LIIDSKL--QIYFSQTLKGEIIGGIEDKREYKFEEFTISISNAIKFLKGIRELIKGIDGI 288 Query: 296 HVVRQWAGHYAKTPDNNPAIG---ELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRT 352 ++R W+G+Y TPD++ +G + E ++ G+SGHG M AP + +A+ I Sbjct: 289 GILRGWSGYYEMTPDSSQIMGYSNDWPEGLFIDAGYSGHGMMFAPYSGKIMADLIADNYK 348 Query: 353 KVPLDWEWYDPYRFERGEL 371 +D + P RF+ +L Sbjct: 349 NKFID--IFSPSRFKLNKL 365 >gb|AAD13136.1| (AF047004) dimethylglycine dehydrogenase-like protein isoform 1; putative sarcosine dehydrogenase [Homo sapiens] Length = 431 Score = 115 bits (285), Expect = 9e-25 Identities = 95/350 (27%), Positives = 159/350 (45%), Gaps = 28/350 (8%) Query: 4 VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 VIGGG +G T Y LAKLG V+ E+ SG+T+ A + + ++L+ ++ Sbjct: 71 VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130 Query: 63 ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 +EL EE G + + Q G LF+A+ + ++ +K+ + L +GV + +++P E K + Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176 P +NV++ + P DG P T +A G ++ P T + VW D G Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 ++T G + +VN W S + M G VP+ H V TE +E Q P Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 309 Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKW--------- 284 V +D+ V + + G Y+++P ++V+ + F L W Sbjct: 310 VRD---HDASVYLRLQGDALSVG---GYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEG 363 Query: 285 AVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVE--DFYVAIGFSGHG 332 A+ +P L + G + TPD+ P +GE E F++ GF+ G Sbjct: 364 AINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAG 413 >gb|AAF57379.1| (AE003789) CG3270 gene product [Drosophila melanogaster] Length = 440 Score = 112 bits (278), Expect = 6e-24 Identities = 108/382 (28%), Positives = 165/382 (42%), Gaps = 37/382 (9%) Query: 4 VIGGGIIGVATAYELA----KLGEEV---VVFEKRYFGSGSTFRCASGIRAQFTDEANIK 56 +IGGG +G ++A+ L +LG ++ VV + S ST G+R QF+ NI+ Sbjct: 36 IIGGGGMGASSAFWLKSRALQLGRKLNVLVVERDAGYTSASTVLSVGGVRQQFSLAENIE 95 Query: 57 LMKYSIERWKELSEELGH-NIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITP 115 + + E LG ++ +Q GYL LA+ E+ KN KLQN G +L+ P Sbjct: 96 MSLFGYNFVVNGREHLGDVDLCYQPNGYLILAS-EKGAHILAKNSKLQNELGARNELLGP 154 Query: 116 EEAKEIVPPLNVEEFLAGAWN-PEDGKASPFHTLYAYKKAGEKLGVKFYPYTEV--VWID 172 E ++ P L+ E G ++G P+ L YKK LG F + V W D Sbjct: 155 EALRQRFPWLSTEGVELGCHGIDKEGWFDPWALLMGYKKKARALGANFANGSVVGFEWND 214 Query: 173 GGREHKWKI---KTTKGEFEVDVIVNATNAWGSRINSMIG-----------KDIVPITPF 218 G + + + D V A A+ ++ + G +P+ P Sbjct: 215 SGGLSGAVVDAGDVLQRTVKFDTCVLAAGAYSGQVARLAGIGDKEAKEASLSVALPVEPR 274 Query: 219 KH--QLVKTEPLE-RGQIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTY 275 K +V T+ G PL P + +Y +DG G +CG + +P+ T Sbjct: 275 KRYVYVVSTQGKNCPGLATPLTVDP--DGTYFRRDGLCGNFLCGRSPNEDEEPECETLDV 332 Query: 276 D---FVKEVLKWAVKIIPALRHVHVVRQWAGHY-AKTPDNNPAIGE--LVEDFYVAIGFS 329 D F +V +PA V + WAG Y T D N IG + ++A GFS Sbjct: 333 DHGYFETDVWPTLANRVPAFESVKIQSSWAGFYDHNTFDANGVIGRHPHYSNLFIAAGFS 392 Query: 330 GHGFMMAPAVAQALAERIVKGR 351 GHG PAV +A++E I+ G+ Sbjct: 393 GHGIQQTPAVGRAISELILDGK 414 >gb|AAF57796.1| (AE003802) CG6385 gene product [Drosophila melanogaster] Length = 894 Score = 111 bits (276), Expect = 1e-23 Identities = 89/371 (23%), Positives = 169/371 (44%), Gaps = 25/371 (6%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63 VIGGG G T Y LA+ G + V+ E+ +G+T+ A + ++ +I+L+ S Sbjct: 41 VIGGGSAGCHTLYHLARRGVKAVLLERAQLTAGTTWHTAGLLWRLRPNDVDIQLLANSRR 100 Query: 64 RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVP 123 ++L EE + + Q G +F+A E ++ +++ + + G+ ++++PE+ +++ P Sbjct: 101 MLQQLEEETELDPGWIQNGGIFIAHNETRLDEYRRLATVGSALGIENQVLSPEDTQKLFP 160 Query: 124 PLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWK--- 180 L+ F+ ++P DG P A KKA LG + V + + + K Sbjct: 161 LLDPSAFVGALYSPGDGVMDPAMLCAALKKAATNLGAQVIENCGVDDLLLEQTARGKKVV 220 Query: 181 -IKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCP 239 + T G+ + + +VNAT WG + + G + P+ P KH + +E + + P + Sbjct: 221 GVSTPFGDIKAEKVVNATGVWGRDLVARHGTHL-PLVPMKHAYIVSESIPGVRGLPNIRD 279 Query: 240 PAWNDSYVIQDGEDGGVICGTALEYKSDP---DDVTPTYDFVKEVLKWAV---------K 287 ++ + IQ G IC Y+ +P + V + F L W+V K Sbjct: 280 HDYSTYFRIQ----GDAICMGG--YEPNPILLEPVPKDFHFGLYELDWSVFETHVEGAQK 333 Query: 288 IIPALRHVHVVRQWAGHYAKTPDNNPAIG--ELVEDFYVAIGFSGHGFMMAPAVAQALAE 345 + P+ V G + TPD+ P +G ++ Y GF+ G M + A Sbjct: 334 LCPSYAKYGVKSTVCGPESFTPDHKPLMGPDPNLDGLYHNCGFNSAGMMFGGGCGEQTAL 393 Query: 346 RIVKGRTKVPL 356 +++G+ +P+ Sbjct: 394 WVIQGQPDLPM 404 >pir||E72254 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981997|gb|AAD36502.1|AE001795_5 (AE001795) conserved hypothetical protein [Thermotoga maritima] Length = 479 Score = 108 bits (267), Expect = 1e-22 Identities = 88/365 (24%), Positives = 172/365 (47%), Gaps = 14/365 (3%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRY-FGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 VIGGG+ G A EL K EV + EK G G T ++ + A + D ++ Sbjct: 5 VIGGGVFGSLIARELTKYDLEVTLIEKNLDVGWGVTKANSAVVHAGYDDPPESVRAQFCA 64 Query: 63 E---RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVP-TKLITPEEA 118 +++LS+EL + F++ G +A +EE++ ++ +K GVP ++ +E Sbjct: 65 SGNAMYEDLSKELDFD--FKRIGSFVVAFNDEELKELERLLKQGEENGVPGLTILERDEV 122 Query: 119 KEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHK 178 + P LN E A + P G P+ A + + G+K VV + Sbjct: 123 LSMEPNLNPEVKYA-LYAPTAGITEPWMVAIAAVENAVQNGLKLVLGESVVGFEKVNGRV 181 Query: 179 WKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVC 238 K+ T++GE+E D+++N I + G + VP+ P K + + + +G ++ ++ Sbjct: 182 RKVHTSRGEYEADIVINCAGLHADEIAKLAGAEYVPLHPRKGEYILLDKKLQGLVKRVIF 241 Query: 239 PPAWNDS--YVIQDGEDGGVICGTALEYKSD--PDDVTPTYDFVKEVLKWAVKIIPALRH 294 P S ++ DGG++ G E + D T + +++V ++ +++P+L Sbjct: 242 PTPTKISKGILVLPTVDGGILLGPTAEDLPEEMKDRPITTREGLEKVREFTRRLVPSLDF 301 Query: 295 VHVVRQWAGHYAKTPDNN--PAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRT 352 VV+ ++G ++P + + E V++F + G APAVA+ + E +++ + Sbjct: 302 SLVVKTFSGLRPESPQKDFFIKVSETVKNFVNVMATRSPGLTAAPAVAKYVVEELIQEKM 361 Query: 353 KVPLD 357 ++PL+ Sbjct: 362 RIPLE 366 >gi|10955084 agaE [Agrobacterium tumefaciens] >gi|11352852|pir||T45533 agaE protein [imported] - Agrobacterium tumefaciens plasmid pTi15955 >gi|2665709|gb|AAB88469.1| (AF242881) agaE [Agrobacterium tumefaciens] Length = 437 Score = 106 bits (261), Expect = 6e-22 Identities = 98/420 (23%), Positives = 157/420 (37%), Gaps = 67/420 (15%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63 VIGGGI+GV+TA ELA+ G V + EK + R +R D + I L S+ Sbjct: 23 VIGGGIVGVSTALELAERGISVALCEKGLIAGEQSGRNWGWVRQMGRDASEIPLAVESLN 82 Query: 64 RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVP 123 WK L+ +G F+QTG +L + ++ + + G+ ++L+ EE ++ +P Sbjct: 83 LWKGLNARIGEETGFRQTGIAYLCRNTRQEAEYEAWLVHARKHGLDSRLLKKEELRQHLP 142 Query: 124 PLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKIKT 183 + + F A DG+A P A + + G V I+ + T Sbjct: 143 GM-ADGFTAALHTSTDGRAEPSKAAPAIARGAIRAGAHIITGCAVRSIERSGGAVSGVVT 201 Query: 184 TKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPPAWN 243 +G +V A AW + +G D F + +E + P Sbjct: 202 ERGRIACSSVVLAGGAWSRLFSGNMGID------FPQLKILATVARATSVEGVPDMPVGA 255 Query: 244 DSYVIQDGEDG--GVICGTALEYKSDPDDVTPTYDFVKEVLK------------------ 283 D++ + +DG + A PD DF+ ++K Sbjct: 256 DNFSFRRRQDGSFNIAMRNANVAPIVPDSFRLFTDFMPTLIKGWDELTLRVGSRFIEEWR 315 Query: 284 ----WA-----------------------------VKIIPALRHVHVVRQWAGHYAKTPD 310 WA VK PA + + WAG TPD Sbjct: 316 TPRSWAADAISPFEQVRILDPKPFERFNREGLAHLVKAFPAFADSRITQSWAGLIDVTPD 375 Query: 311 NNPAIGEL--VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLDWEWYDPYRFER 368 P IG + F++A GFSGHGF + P + +A+ + + V P+RF+R Sbjct: 376 AIPVIGPAGGIPGFFIASGFSGHGFGIGPGSGKLMADLVTNAQPSVD-----PAPFRFDR 430 >pir||H82968 sarcosine oxidase beta subunit PA5416 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951743|gb|AAG08801.1|AE004954_3 (AE004954) sarcosine oxidase beta subunit [Pseudomonas aeruginosa] Length = 416 Score = 105 bits (260), Expect = 8e-22 Identities = 87/355 (24%), Positives = 159/355 (44%), Gaps = 13/355 (3%) Query: 4 VIGGGIIGVATAYELAKLG--EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61 ++GGG G+ATAY LAK V V EK + G G+T R + +R+ + + + L +++ Sbjct: 37 IVGGGGHGLATAYYLAKEHGISNVAVVEKGWLGGGNTARNTTIVRSNYLWDESALLYEHA 96 Query: 62 IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 ++ W+ LS++L +N+MF Q G L T +++ ++ + GV +L+ ++ E Sbjct: 97 MKLWEGLSQDLNYNVMFSQRGVYNLCHTLQDMRDGERRVSANRLNGVDGELLNAQQVAEE 156 Query: 122 VPPLNVEE-----FLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176 +P L+ + + G A + + +A + LGV TEV Sbjct: 157 IPYLDCSKSTRYPIMGATIQRRGGVARHDAVAWGFARAADALGVDLIQQTEVTGFRKQDG 216 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 ++T +G F V A S + + +P+ Q + +EPL + I+ + Sbjct: 217 AVIGVETNRG-FIGARRVGVVTAGNSGHMARLAGFRLPLESHPLQALVSEPL-KPIIDSV 274 Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296 + A + I + G ++ G ++ + +Y ++ L+ V++ P L V Sbjct: 275 IMSNAVHG--YISQSDKGDLVIGAGIDGYNGYGQ-RGSYPVIEHTLQAIVEMFPVLSRVR 331 Query: 297 VVRQWAGHYAKTPDNNPAIGEL-VEDFYVAIGFSGHGFMMAPAVAQALAERIVKG 350 + RQW G TPD P IG+ V++ + G+ GF P A + KG Sbjct: 332 MNRQWGGIVDTTPDACPIIGKTPVQNLFFNCGWGTGGFKATPGSGNVFAATLAKG 386 >dbj|BAB05153.1| (AP001512) glycine oxidase (sarcosine oxidase) [Bacillus halodurans] Length = 365 Score = 103 bits (255), Expect = 3e-21 Identities = 93/374 (24%), Positives = 168/374 (44%), Gaps = 23/374 (6%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEAN-----IKLM 58 V+GGG+IG+A A+EL G +V V E+ G G A+G+ A F++ L Sbjct: 3 VLGGGVIGLAVAFELKVRGHQVTVLEQGLCG-GQASGAAAGMLAPFSEIGEDPNDFFHLA 61 Query: 59 KYSIER---WKELSEEL-GHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLIT 114 S++ W++ +E+ G + + Q+G L E + + Q FGV +++++ Sbjct: 62 HESLKMYPDWQQAVKEISGKSFEYVQSGSLHCVYHEADFLELESRQHWQGTFGVESEILS 121 Query: 115 PEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGG 174 ++ + + P ++ +E + + PE+ + A + KLGV + I+ Sbjct: 122 QQQIRALEPNIS-DEIIGAIYYPEESHLFAPDYVKALEIGCRKLGVTIEDEVGHISIEAW 180 Query: 175 REHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIE 234 EH+ + ++ D ++ AW S VP+ P + Q+ E + G + Sbjct: 181 MEHQVLRGPSGKQWAGDRLIVCAGAWASEHEETFSLR-VPVYPIRGQICAYE-VPAGDVR 238 Query: 235 PLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRH 294 +V + Y++ G +G V+ G + + D T T +K + W I P L Sbjct: 239 HIVYT---SQGYIVPKG-NGTVVNGASEDIAG--YDTTVTEQGIKRLTNWNGHIFPFLNE 292 Query: 295 VHVVRQWAGHYAKTPDNNPAIGELVEDFYV--AIGFSGHGFMMAPAVAQALAERIVKGRT 352 + WAG T D P IGE + +V A G +G +++P A+ +A+ + +T Sbjct: 293 LTPFHTWAGLRPATQDGYPMIGETKKAPHVVFATGHYRNGILLSPITAKVVADVVEGKKT 352 Query: 353 KVPLDWEWYDPYRF 366 +VPL +DP RF Sbjct: 353 EVPL--TMFDPMRF 364 >sp|O31616|GLOX_BACSU GLYCINE OXIDASE >gi|7475812|pir||B69845 sarcosine oxidase homolog yjbR - Bacillus subtilis >gi|2633521|emb|CAB13024.1| (Z99110) similar to sarcosine oxidase [Bacillus subtilis] Length = 369 Score = 102 bits (252), Expect = 7e-21 Identities = 102/378 (26%), Positives = 170/378 (43%), Gaps = 32/378 (8%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCAS--GIRAQFTD-EANIKLMKY 60 VIGGGIIG A AY LAK + +FE G +T A G A+ + +A + Sbjct: 9 VIGGGIIGSAIAYYLAKENKNTALFESGTMGGRTTSAAAGMLGAHAECEERDAFFDFAMH 68 Query: 61 SIERWKELSEEL----GHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPE 116 S +K L EEL G +I G LA +EE+V ++ L + + E Sbjct: 69 SQRLYKGLGEELYALSGVDIRQHNGGMFKLAFSEEDVLQLRQMDDLDS-----VSWYSKE 123 Query: 117 EAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176 E E P + + F A ++ +D P+ AY KA + LG + + +T V+ ++ E Sbjct: 124 EVLEKEPYASGDIFGA-SFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGE 182 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 + IKT G+ + +V A+ W +G + + VK E L + Sbjct: 183 ALF-IKTPSGDVWANHVVVASGVWSGMFFKQLGLNNAFLP------VKGECLSVWNDDIP 235 Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDF--VKEVLKWAVKIIPALRH 294 + ++D I + G ++ G ++ P D + T D ++ V+K A ++PA+++ Sbjct: 236 LTKTLYHDHCYIVPRKSGRLVVGATMK----PGDWSETPDLGGLESVMKKAKTMLPAIQN 291 Query: 295 VHVVRQWAGHYAKTPDNNPAIGELVEDFYV--AIGFSGHGFMMAPAVAQALAERIVKGRT 352 + V R WAG T D P IG ED + A G +G ++APA +++ I+ Sbjct: 292 MKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILLAPATGALISDLIMNKE- 350 Query: 353 KVPLDWEWYDPYRFERGE 370 ++ +W +R +R E Sbjct: 351 ---VNQDWLHAFRIDRKE 365 >gb|AAD53399.2|AF095736_1 (AF095736) unknown [Homo sapiens] Length = 328 Score = 102 bits (252), Expect = 7e-21 Identities = 71/241 (29%), Positives = 115/241 (47%), Gaps = 8/241 (3%) Query: 4 VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 VIGGG +G T Y LAKLG V+ E+ SG+T+ A + + ++L+ ++ Sbjct: 27 VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 86 Query: 63 ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 +EL EE G + + Q G LF+A+ + ++ +K+ + L +GV + +++P E K + Sbjct: 87 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 146 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176 P +NV++ + P DG P T +A G ++ P T + VW D G Sbjct: 147 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 206 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 ++T G + +VN W S + M G VP+ H V TE +E Q P Sbjct: 207 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 265 Query: 237 V 237 V Sbjct: 266 V 266 >gi|6005868 sarcosine dehydrogenase; dimethylglycine dehydrogenase-like 1 [Homo sapiens] >gi|11429603|ref|XP_005639.1| sarcosine dehydrogenase [Homo sapiens] >gi|5902972|gb|AAD53400.2| (AF095737) unknown [Homo sapiens] Length = 396 Score = 101 bits (250), Expect = 1e-20 Identities = 68/233 (29%), Positives = 112/233 (47%), Gaps = 8/233 (3%) Query: 4 VIGGGIIGVATAYELAKLGEE-VVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 VIGGG +G T Y LAKLG V+ E+ SG+T+ A + + ++L+ ++ Sbjct: 71 VIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTR 130 Query: 63 ERW-KELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 +EL EE G + + Q G LF+A+ + ++ +K+ + L +GV + +++P E K + Sbjct: 131 RVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTL 190 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLG---VKFYPYTEV-VWIDG-GRE 176 P +NV++ + P DG P T +A G ++ P T + VW D G Sbjct: 191 YPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVR 250 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLE 229 ++T G + +VN W S + M G VP+ H V TE +E Sbjct: 251 RVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVK-VPLVAMHHAYVVTERIE 302 >gb|AAB03674.1| (U62481) dimethylglycine dehydrogenase-like protein [Rattus norvegicus] >gi|1449112|gb|AAB04667.1| (L79910) dimethylglycine dehydrogenase [Rattus norvegicus] Length = 278 Score = 96.0 bits (235), Expect = 7e-19 Identities = 66/241 (27%), Positives = 111/241 (45%), Gaps = 8/241 (3%) Query: 4 VIGGGIIGVATAYELAKLGEEVV-VFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSI 62 VIGGG +G T Y LAKLG V +R SG+T+ A + + ++L+ ++ Sbjct: 32 VIGGGSLGCQTLYHLAKLGVSGVGAAGERAMTSGTTWHTAGLLWQLRPSDVEVELLAHTR 91 Query: 63 ERWK-ELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 + +L EE G + + Q G F+A+ ++ ++ +K+ + L +G+ + +++P E K++ Sbjct: 92 QVVSHDLEEETGLHTGWIQNGGFFIASNQQRLDEYKRLMSLGKAYGIESHVLSPAETKDL 151 Query: 122 VPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI-----DGGRE 176 P +NV++ + P DG P T +A G + V I D G Sbjct: 152 YPLMNVDDLYGTLYVPRDGTMDPAGTCTTLTRAAVARGAQVIENCAVTGIRVRTDDFGVR 211 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 ++T G + +VN W S + M G VP+ H V TE +E Q P Sbjct: 212 RVTAVETQHGSIQTPCVVNCAGVWASSVGRMAGVK-VPLVAMHHAYVVTERIEGIQNMPN 270 Query: 237 V 237 V Sbjct: 271 V 271 >dbj|BAB05760.1| (AP001514) unknown conserved protein [Bacillus halodurans] Length = 376 Score = 93.2 bits (228), Expect = 4e-18 Identities = 91/363 (25%), Positives = 157/363 (43%), Gaps = 37/363 (10%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFG-------SGSTFRCASGI-RAQFTDEANI 55 +IGGG+IG++ A AK G V+V EK G +G A G+ R + Sbjct: 9 IIGGGVIGLSIAIHTAKKGANVLVVEKDRLGQEASGGRAGLLTTVAEGVDRHDPYSIFSR 68 Query: 56 KLMKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITP 115 + ++Y ++ EL E+ + + L LA E+E + + +Q K ++ Sbjct: 69 ESLQYLLQWIPELEEKTQISSGLVKQNLLRLALHEQEAALLEDHWLMQTETNSQIKRLSA 128 Query: 116 EEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGR 175 EEA+ + P L+ + + +P++ P L A + +LGV TEV+ Sbjct: 129 EEARTLEPLLS-NDLIMAICSPDEYHLEPSLYLNALARMARQLGVTIREQTEVIQFIHQN 187 Query: 176 EHKWKIKTTKG-EFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIE 234 + + T G + + + A AW S + S + K VP+ P K QL+ L++G + Sbjct: 188 NRMYGVVTNTGTQIVAETTILAAGAW-SHLLSRLAKVKVPVYPLKGQLI---VLKQGDTD 243 Query: 235 PLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVT--------PTYDFVKEVLKWAV 286 V + Y++ +G V+ G E + +T P +D+V E+ W + Sbjct: 244 LNVMINT-SKGYILSK-PNGTVVLGATSEKEKFNKFITAKGIQELLPLFDYVPELKNWEI 301 Query: 287 KIIPALRHVHVVRQWAGHYAKTPDNNPAIGELV--EDFYVAIGFSGHGFMMAPAVAQALA 344 + + WAG TPD P IG + E +Y+A G S HG +++ +A Sbjct: 302 QHL-----------WAGLRPATPDGQPIIGYVPEWEGWYLATGHSRHGVLLSGWTGHLVA 350 Query: 345 ERI 347 E + Sbjct: 351 EEL 353 >sp|O87388|SAOX_RHIME SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE OXIDASE SUBUNIT B) >gi|3687680|gb|AAC62218.1| (AF055582) sarcosine oxidase subunit B [Sinorhizobium meliloti] Length = 416 Score = 92.4 bits (226), Expect = 8e-18 Identities = 95/376 (25%), Positives = 159/376 (42%), Gaps = 16/376 (4%) Query: 4 VIGGGIIGVATAYELAK-LG-EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61 ++GGG G+ATAY LAK G V V EK Y GSG+ R + IR+ + N + S Sbjct: 36 IVGGGGHGLATAYYLAKEFGITNVAVLEKNYIGSGNVGRNTTIIRSNYLLPGNNPFYELS 95 Query: 62 IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 ++ W+ L ++ N M Q G L L ++ + +A+ + GV +L+ +++ Sbjct: 96 MKLWEGLEQDFNFNAMVSQRGVLNLFHSDAQRDAYTRRGNAMRLHGVDAELLYRAAVRKM 155 Query: 122 VPPLNVEE----FLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREH 177 +P L+ + G G + Y + + GV EV I Sbjct: 156 LPFLDFDNARFPIQGGLLQRRGGTVRHDAVAWGYARGADSRGVDIIQNCEVTGIRRENGR 215 Query: 178 KWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLV 237 ++T++G + A S++ M G + PI Q +E L + I+ +V Sbjct: 216 VIGVETSRGFIGCAKLALAAAGNSSQVAEMAGLRL-PIESHVLQAFVSEGL-KPFIDGVV 273 Query: 238 CPPAWNDSYVIQDGEDGGVICGTALE-YKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296 A + + + + GG++ G ++ Y S V+ V + +IPAL V Sbjct: 274 TFGAGH--FYVSQSDKGGLVFGGDIDGYNSYAQ--RGNLATVEHVAEAGKAMIPALSRVR 329 Query: 297 VVRQWAGHYAKTPDNNPAIGEL-VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVP 355 V+R W G + D +P I +++ Y+ G+ GF PA A + +G + Sbjct: 330 VLRSWGGIMDMSMDGSPIIDRTPIDNLYLNAGWCYGGFKATPASGFCFAHLLARGAPQKT 389 Query: 356 LDWEWYDPYRFERGEL 371 D RFERG L Sbjct: 390 AAAFRLD--RFERGFL 403 >pir||F83487 hypothetical protein PA1267 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9947200|gb|AAG04656.1|AE004556_6 (AE004556) hypothetical protein [Pseudomonas aeruginosa] Length = 371 Score = 92.1 bits (225), Expect = 1e-17 Identities = 99/378 (26%), Positives = 165/378 (43%), Gaps = 37/378 (9%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63 V+G GI+G A A+ELA+ G +V+V + R G+T + A + A + L YS + Sbjct: 7 VVGAGIVGSACAHELARRGLDVLVLDSRR--GGATAVGMGHLVAMDDNPAELALSDYSTQ 64 Query: 64 RWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVP 123 W+ + EL + ++ G L+LA E+ ++ + GV +++ + P Sbjct: 65 AWRAWAAELPEDCAYRGCGTLWLAADASELAEAERKRQALQAAGVACRMLGAARLYALEP 124 Query: 124 PLNVEEFLAGAWNPE-DGKA-SPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKI 181 L LAGA DG +P + +AG +L Y EV +DG R + Sbjct: 125 ALRPG--LAGALEVSGDGILYAPNAARWLLDQAGPRLRRL---YAEVSEVDGSR-----L 174 Query: 182 KTTKGEF-EVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEP---------LERG 231 + G + + +V A + + + PI P K L+ T+ +E G Sbjct: 175 RLADGRWLSAEALVLANGIHAGELCAEL-----PIRPKKGHLLITDRYPGTLRHQLVELG 229 Query: 232 QIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKS-DPDDVTPTYDFVKEVLKWAVKIIP 290 + + ++ Q G V G++ ++ + DP P + +L+ A+ +P Sbjct: 230 YVSSAHASSGTSVAFNAQPRPTGQVFLGSSRQFDTLDPQVEGPV---LARMLRRALDYLP 286 Query: 291 ALRHVHVVRQWAGHYAKTPDNNPAIGE--LVEDFYVAIGFSGHGFMMAPAVAQALAERIV 348 L ++ +R W G A TPD P +GE ++A+G G G AP A+ LA ++ Sbjct: 287 GLAGLNAIRAWTGFRAATPDGLPLLGEHPAQPGLWLAVGHEGLGVTTAPGSARLLAAQLF 346 Query: 349 KGRTKVPLDWEWYDPYRF 366 G T PLD Y P RF Sbjct: 347 -GETP-PLDPTPYLPQRF 362 >pir||H83370 hydrogen cyanide synthase HcnC PA2195 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|6644364|gb|AAF21030.1|AF208523_3 (AF208523) HcnC [Pseudomonas aeruginosa] >gi|9948217|gb|AAG05583.1|AE004646_4 (AE004646) hydrogen cyanide synthase HcnC [Pseudomonas aeruginosa] Length = 417 Score = 90.9 bits (222), Expect = 2e-17 Identities = 82/313 (26%), Positives = 142/313 (45%), Gaps = 23/313 (7%) Query: 63 ERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIV 122 E +EL E G + F++TG ++ +E+ + + + + + EE + Sbjct: 109 ELHRELIERHGMDFKFERTGLKYVIQDDEDRQYAEHIVAQIPHLAEQVRWLDREELRRAE 168 Query: 123 PPLN-----VEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI-DGGRE 176 P ++ EFL D + SPF AY +A + GV+ P T V + GR Sbjct: 169 PAVSHAAHGALEFLC------DHQVSPFRLADAYLEAARQNGVELLPGTNVTGVLRQGRR 222 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPL 236 G ++NA AW + ++ M +P+ P K Q+V TE + R L Sbjct: 223 ISGVRTDNAGVLHCRTLINAAGAWAAELSEMATGRRIPVKPVKGQIVLTERMPRLLNGCL 282 Query: 237 VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296 +D Y+ Q ++G ++ G+ E K DV+ T+ + +++ AV+ +P L+ V+ Sbjct: 283 TT----SDCYMAQK-DNGEILIGSTTEDKGF--DVSNTFPEIAGLVQGAVRCVPELQQVN 335 Query: 297 VVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKV 354 + R WAG +PD P +G + VE + A G G ++ A+ L +R+V T + Sbjct: 336 LKRTWAGLRPGSPDELPILGPVAEVEGYLNACGHFRTG-ILTSAITGVLLDRLVHEET-L 393 Query: 355 PLDWEWYDPYRFE 367 PLD + RF+ Sbjct: 394 PLDIAPFLAARFQ 406 >gb|AAK42656.1| Glycerol-3-phosphate dehydrogenase chain A (glpA) [Sulfolobus solfataricus] Length = 445 Score = 89.7 bits (219), Expect = 5e-17 Identities = 82/311 (26%), Positives = 142/311 (45%), Gaps = 20/311 (6%) Query: 2 IGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFR----CASGIRAQFTDEANIKL 57 + VIGGG+ G+ TA +LA G +V + ++ G G++ + SG R TD + + Sbjct: 20 VTVIGGGVSGLFTALDLALRGIDVTLVDRGDIGYGTSGKFHGLLHSGARYAVTDPDSAR- 78 Query: 58 MKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEE 117 I+ K +S+ H + + TG +FL T+++++ + IK N+ G+ +K+I +E Sbjct: 79 --ECIQENKIISKIAPHTV--KDTGGVFLGITDDDLQFSETFIKALNKVGIESKVIDVKE 134 Query: 118 AKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI------ 171 + P +N + +A W P D + L + G K Y EVV I Sbjct: 135 VLQKEPFINRDTKMA-IWVP-DKVVYGYDLLASVAITASLNGAKILTYNEVVEIIRENNN 192 Query: 172 DGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERG 231 G + KI + D+IVN W I M G + +PI P +V + Sbjct: 193 VKGVKVLDKINNNTNVIKSDIIVNTAGPWSFNIIKMAGLEEIPIMPTAGIIVVFDKRVNN 252 Query: 232 QIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPA 291 + + PP +D +I D ++ GT DPD+ T + + + ++ +IP Sbjct: 253 MVINRLRPP--SDGDIIVPYADSSIL-GTTATIIEDPDNFTISDEDIAMLVNEGAYLIPK 309 Query: 292 LRHVHVVRQWA 302 L+++ VVR +A Sbjct: 310 LKNMRVVRSYA 320 >sp|Q52671|SAOX_RHOCA SARCOSINE OXIDASE BETA SUBUNIT (SARCOSINE OXIDASE SUBUNIT B) >gi|1353872|gb|AAB01814.1| (U46071) sarcosine oxidase [Rhodobacter capsulatus] Length = 208 Score = 86.6 bits (211), Expect = 4e-16 Identities = 52/171 (30%), Positives = 88/171 (51%), Gaps = 6/171 (3%) Query: 4 VIGGGIIGVATAYELAKLG--EEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61 V+G G G+ATAY L K+ + V + EK + G G+T R + IR+ + + + + + + Sbjct: 37 VVGAGGHGLATAYYLGKVHGIKNVAIIEKGWLGGGNTGRNTTIIRSNYLQDPSAAIYEKA 96 Query: 62 IERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEI 121 ++ LS++L +N+MF G L LA +E E+ +K+ + N V T+ I P+E K++ Sbjct: 97 RSLYEGLSQDLNYNVMFSPRGLLMLAQSEHEMRGYKRTVYANNLQNVETRWIEPKEVKKL 156 Query: 122 VPPLNVE----EFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEV 168 VP LN+ L + G A + Y +A +G+ TEV Sbjct: 157 VPILNIAGPRYPVLGALLQEKGGTARHDAVAWGYARACSDMGMDLLQNTEV 207 >pir||E82983 probable oxidoreductase PA5309 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951625|gb|AAG08694.1|AE004943_10 (AE004943) probable oxidoreductase [Pseudomonas aeruginosa] Length = 439 Score = 82.7 bits (201), Expect = 7e-15 Identities = 91/375 (24%), Positives = 159/375 (42%), Gaps = 53/375 (14%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRC--------------------AS 43 V+GGG GV TA ELA+ G VV+ E G G++ R A Sbjct: 42 VVGGGFSGVNTALELAQRGFSVVLLEAHQIGWGASGRNGGQLIRGVGHDVEQFLPVIGAD 101 Query: 44 GIRAQFTDEANIKLMKY-SIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKL 102 G++A +KLM ++E + E+ + + GY LA + + F+++++ Sbjct: 102 GVKA-------LKLMGLEAVEIVRRRVEQYAIDCDLRW-GYCDLANKPGDYQGFREDMEE 153 Query: 103 QNRFGV--PTKLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGV 160 G +L+ E + ++ + ++ G + G P + + A + LGV Sbjct: 154 LQALGYRHEMRLVPAAEMRSVI---GSDRYVGGLVDMGSGHLHPLNLVLGEAAAAQSLGV 210 Query: 161 KFYPYTEVVWIDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKH 220 + + + V+ ID G E + + T G+ +V NA+ + +N ++G ++P + Sbjct: 211 RLFERSTVMRIDYGTEVQ--VHTATGKVRAKTLVLGCNAYMNDLNPLLGGKVLPAGSY-- 266 Query: 221 QLVKTEPLERGQIEPLVCP-PAWNDSYVIQD----GEDGGVICGTALEYKS-DPDDVTPT 274 ++ TEPL+ L+ A D V D D ++ G A Y DP D+ Sbjct: 267 -VIATEPLDEKLARQLLPQNMAVCDQRVALDYYRLSADNRLLFGGACHYSGRDPSDIAA- 324 Query: 275 YDFVKEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHG 332 +++ + +++ P L +V + QW G + P IG L + Y A +SGHG Sbjct: 325 --YMRPKM---LEVFPQLANVRIDYQWGGMIGIGANRLPQIGRLPGQPNVYFAQAYSGHG 379 Query: 333 FMMAPAVAQALAERI 347 Q LAE I Sbjct: 380 VNATHLAGQLLAEAI 394 >gb|AAC38596.1| (AF053760) hydrogen cyanide synthase HcnC [Pseudomonas fluorescens] Length = 417 Score = 82.7 bits (201), Expect = 7e-15 Identities = 99/403 (24%), Positives = 168/403 (41%), Gaps = 64/403 (15%) Query: 4 VIGGGIIGVATAYELAKLGE-EVVVFEKRYFGSGST---------------------FRC 41 + GGG+IG + AY+L+K + +V + + + G+ S FR Sbjct: 9 IAGGGVIGASCAYQLSKRKDLKVALIDAKRPGNASRASAGGLWAIGESVGLGCGVIFFRM 68 Query: 42 ASGIR-------AQFTDEANIKLMKYSI--------ERWKELSEELG--HNI--MFQQTG 82 S R A D + ++ S E + L EL HN+ F+QTG Sbjct: 69 MSANRKREAQGSAVVVDSSTPHILPQSFFDFALQSNELYPRLHRELMGLHNMDFKFEQTG 128 Query: 83 YLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAKEIVPPLNVE-----EFLAGAWNP 137 F+ EE+ + + + + + P ++ E EFL Sbjct: 129 LKFVIYDEEDRLYAEHIVGCIPHLSDQVRWLDQAALRASEPNVSHEAQGALEFLC----- 183 Query: 138 EDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGREHKWKIKT-TKGEFEVDVIVNA 196 D + +PF AY + + GV Y T V + +KT G F ++NA Sbjct: 184 -DHQVNPFRLTDAYTEGARQNGVDVYFNTNVTGVLHQGNRVSGVKTDVAGLFRCTTLINA 242 Query: 197 TNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEPLVCPPAWNDSYVIQDGEDGGV 256 AW + ++ +P+ P K Q++ TE + + L +D Y+ Q ++G + Sbjct: 243 AGAWAAELSLQATGIEIPVKPVKGQILLTERMPKLLNGCLTT----SDCYMAQK-DNGEI 297 Query: 257 ICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIG 316 + G+ E K DVT TY + +++ AV+ +P L HV++ R WAG +PD P +G Sbjct: 298 LIGSTTEDKGF--DVTTTYPEINGLVQGAVRCVPELAHVNLKRCWAGLRPGSPDELPILG 355 Query: 317 EL--VEDFYVAIGFSGHGFMMAPAVAQALAERIVKGRTKVPLD 357 + VE + A G G ++ A+ L +++V +PLD Sbjct: 356 PMDGVEGYLNACGHFRTG-ILTSAITGVLLDKLV-NEEALPLD 396 >pir||H70361 conserved hypothetical protein aq_707 - Aquifex aeolicus >gi|2983300|gb|AAC06892.1| (AE000703) hypothetical protein [Aquifex aeolicus] Length = 353 Score = 81.9 bits (199), Expect = 1e-14 Identities = 101/376 (26%), Positives = 175/376 (45%), Gaps = 40/376 (10%) Query: 4 VIGGGIIGVATAYELAKLGEEV--VVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYS 61 VIGGG+IG++ EL G +V +V +KR G+++ A G+ A F++ +++S Sbjct: 5 VIGGGVIGLSIGVELLLAGHDVRLLVRDKR---EGASW-VAGGMLAPFSEGLRGDFLRFS 60 Query: 62 IER---WKELSEEL----GHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLIT 114 +E W + E L G + F Q G L +A E+E + ++++K ++ V LI+ Sbjct: 61 VESLRLWHDYLERLKEISGRKVFFSQ-GILRVAFDEKEEKKLREDVKFYSQ-EVCQNLIS 118 Query: 115 PEEAKEIVP--PLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWID 172 +A+E++ P E G ++G + A A EKLG + V + Sbjct: 119 -YDAEELLKEFPYLSSEVRYGVIYGDEGNVDTEELMEALYVAFEKLGGEIINEDAVKILR 177 Query: 173 GGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTE-PLERG 231 G E K+ EF D V AT AW + G P+ P K Q+++ E PL+ Sbjct: 178 NG-ERIEKVFGFFEEFTADYYVFATGAW---LKEHFG---FPVFPVKGQILRVEAPLKDY 230 Query: 232 QIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPA 291 + + +Y+I +D ++ G E + D T + VK++ + A+ +P Sbjct: 231 VVYS-------SRAYIIPREKD--LLIGATTE--NAGFDTKTTLEGVKKLSEGAISSVPQ 279 Query: 292 LRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQALAERIVKGR 351 L+ ++ G TPD P + E+F V G +G ++APA A+ + I +G Sbjct: 280 LKEAQLLEVRVGFRPGTPDELP-VFYFGENFSVYGGHYRNGILLAPATAEVALKLIDQG- 337 Query: 352 TKVPLDWEWYDPYRFE 367 +V ++ + PYRF+ Sbjct: 338 -EVSEYFKTFSPYRFK 352 >pir||C83407 hypothetical protein PA1918 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9947911|gb|AAG05306.1|AE004617_10 (AE004617) hypothetical protein [Pseudomonas aeruginosa] Length = 466 Score = 80.4 bits (195), Expect = 3e-14 Identities = 89/362 (24%), Positives = 155/362 (42%), Gaps = 46/362 (12%) Query: 2 IGVIGGGIIGVATAYELAKLGEE--VVVFEKRYFGSGSTFRCAS---------GIRAQFT 50 + ++GGG +G+ TA L +L + V++ E+ G G++ R G F Sbjct: 36 VAIVGGGFVGLWTAITLKQLEPDARVLLLEQDVCGGGASGRNGGFVMSWWPKIGTLLGFC 95 Query: 51 DEANIKLMKYSIERW-KELSEELG-HNI--MFQQTGYLFLATTEEEVEAFKKNIKLQNRF 106 EA + + S ER +EL E H+I FQQ G+L+ ATT ++A+ + R Sbjct: 96 SEAQARFLGESAERAIQELGEFCARHDIDAHFQQKGWLWTATTAHHLDAWNDTLAACERL 155 Query: 107 GVPT--KLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYP 164 GV +L E A+ P++ LAG + + P + ++ LGV+ + Sbjct: 156 GVSPFERLDASEVARRTGSPVH----LAGVFERSNATVQPALLVQGMRRVALALGVEIHE 211 Query: 165 YTEVVWIDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVK 224 V I G+ + + + + +V ATNAW + + + + IVP+ + Sbjct: 212 RCGVSQIVPGQPAQ--LLSAGARVQAKAVVLATNAWSAAL-PRLSRLIVPVNS---SIAV 265 Query: 225 TEPLERGQIEPLVCPPAWNDSYVIQDGE----------DGGVICGTALEYKSDPDDVTPT 274 TE + + ++E + W I D + DG + G S + Sbjct: 266 TEAIPQ-RLERI----GWTGGEAITDSQLMVDYYRTTRDGRIAFGKGTGALSYGSRIGRV 320 Query: 275 YDFVKEVLKWAV----KIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSG 330 +D +E L + P+L + +V W+G +T D+ P G L E+ + IG+SG Sbjct: 321 FDVDRESLALTEADFRRTYPSLGDIPLVDGWSGPIDRTYDSLPVFGRLHENIHYGIGWSG 380 Query: 331 HG 332 +G Sbjct: 381 NG 382 >pir||G83298 conserved hypothetical protein PA2776 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9948857|gb|AAG06164.1|AE004705_6 (AE004705) conserved hypothetical protein [Pseudomonas aeruginosa] Length = 427 Score = 79.2 bits (192), Expect = 7e-14 Identities = 88/368 (23%), Positives = 150/368 (39%), Gaps = 42/368 (11%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANI---KLMKY 60 VIG G G++TA L + G +V V E G G++ R I ++ + ++ + K Sbjct: 34 VIGAGYTGLSTALFLLENGFKVTVLEAAKVGFGASGRNGGQIVNSYSRDIDVIERTVGKR 93 Query: 61 SIERWKELSEELGHNIMFQQTGY----------LFLATTEEEVEAFKKNIKLQNRFGVPT 110 + E++ E G I + Y +F A TE++++ + +L R+G Sbjct: 94 EAQLLGEMAFEGGRIIRERVARYGIQCDLKDGGVFAAFTEKQMDHLRAQKQLWERYGHNQ 153 Query: 111 KLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVW 170 I +AK I + + ++ G + G P + A E LG + Y + Sbjct: 154 LEIM--DAKRIREVVATDNYIGGMLDMSGGHIHPLNLALGEAAAVESLGGRIYEQSPATR 211 Query: 171 IDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLER 230 I+ G + T +G+ + IV A NA+ +N ++ + P Q++ TEPL Sbjct: 212 IERGASPV--VHTPQGKVKAKFIVVAGNAY---LNGLVPELAAKSMPCGTQVITTEPLNE 266 Query: 231 GQIEPLV----CPPAWN---DSYVIQDGE----DGGVICGTALEYKSDPDDVTPTYDFVK 279 L+ C N D Y + + GGVI G DP D+ Sbjct: 267 ELAHSLLPQDYCVEDCNYLLDYYRLSGDKRLIYGGGVIYGAR-----DPADIEAI----- 316 Query: 280 EVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAV 339 + +K P L+ V + W G++ T P +G + ++ Y + G SGHG Sbjct: 317 -IRPKMLKTFPQLKDVKIDFAWTGNFLLTLSRLPQVGRIGDNIYYSQGCSGHGVTYTHVA 375 Query: 340 AQALAERI 347 + LAE + Sbjct: 376 GKVLAEAL 383 >gb|AAG20146.1| (AE005092) glycerol-3-phosphate dehydrogenase chain A; GpdA2 [Halobacterium sp. NRC-1] Length = 570 Score = 79.2 bits (192), Expect = 7e-14 Identities = 88/321 (27%), Positives = 143/321 (44%), Gaps = 34/321 (10%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCA----SGIRAQFTDEANIKLMK 59 V+GGG G A +LA G V + E+ G+T R SG R +D+A+ + + Sbjct: 9 VVGGGSTGAGVARDLAMRGLGVTLVEQGNLTHGTTGRMHGLLHSGGRYAVSDQASAR--E 66 Query: 60 YSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAK 119 IE + L E H + +TG LF+ E+ + F++ + +PTK+++ EA+ Sbjct: 67 CIIEN-RVLREIATHCV--DETGGLFVKRPEDSEQYFQEKLAGCEACDIPTKVLSGAEAR 123 Query: 120 EIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPY---TEVVWIDGG-- 174 ++ P L ++ W P D PF + A + ++ G + + T+VV DG Sbjct: 124 QLEPHL-ADDVEKAIWVP-DAAIDPFRLVVANAASAQEHGARIETHSTVTDVVVEDGAVV 181 Query: 175 ---REHKW----KIKTTKGEFEV---DVIVNATNAWGSRINSMIGKDIVPITPFKHQLVK 224 EH ++ T+G EV D +VNA AW R+ M G D V + P K + Sbjct: 182 GVEVEHATGAGKRVHGTEGGTEVIRADHVVNAAGAWAGRLGEMAGVD-VEVRPSKGVMT- 239 Query: 225 TEPLERGQIEPLV--CPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVL 282 + Q++ +V C P + V+ + I GT E +DP+D V V+ Sbjct: 240 --VMNTRQVDTVVNRCRPKGDADIVVP--HETTCILGTTDEEVADPEDYPEQQWEVDMVI 295 Query: 283 KWAVKIIPALRHVHVVRQWAG 303 ++IP L VR + G Sbjct: 296 DELAELIPMLDDARTVRSFWG 316 >pir||S76505 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1001620|dbj|BAA10351.1| (D64002) ThiG protein [Synechocystis sp.] Length = 656 Score = 78.8 bits (191), Expect = 1e-13 Identities = 90/354 (25%), Positives = 151/354 (42%), Gaps = 29/354 (8%) Query: 4 VIGGGIIGVATAYELAKLGE---EVVVFEKRYFGSGSTFRCASGIRAQFTDEAN----IK 56 +IGGGIIG+A A EL KL + +V V + + + S A+G+ A ++ + Sbjct: 9 IIGGGIIGLAIAVEL-KLKQKRLQVTVLSRDFAQAAS--HAAAGMLAPHAEQIAPGPMLD 65 Query: 57 LMKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPE 116 L S R+ E E+L + +TGY EA N + + + E Sbjct: 66 LCLASRWRYGEWVEKL-EQLTGMETGYNPCGILSPVFEAPHGNSSTNSAW------LDQE 118 Query: 117 EAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176 + P L E+ + G W+P+DG+ + A ++A + LGV+ V I Sbjct: 119 TIRYYQPGLG-EDVIGGWWHPDDGQVDNRKLVSALRQAAQSLGVQIQEGVTVQAIAQRHG 177 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTE-PLERGQIEP 235 + T +G F+ D V A +W + + P+ P K Q++ P Q P Sbjct: 178 QVTAVLTDQGSFQADSYVLANGSWAKELLPL------PVFPVKGQMMALRMPAGTHQPYP 231 Query: 236 LVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHV 295 L +Y++ DG +I G E TP ++ +L A+++ PAL Sbjct: 232 LQRVLFGPQTYLV-PRRDGRLIVGATSEQVDWQPHNTP--QGIQTLLGRAIRLFPALGDW 288 Query: 296 HVVRQWAGHYAKTPDNNPAIG-ELVEDFYVAIGFSGHGFMMAPAVAQALAERIV 348 + W G TPD P +G ++ +AIG +G ++AP A +++ I+ Sbjct: 289 AIEDFWWGFRPGTPDEQPFLGYGPCDNLILAIGHYRNGILLAPITAALISDLIL 342 >gb|AAA96395.1| (U38892) N-terminal and C-terminal ends are similar to the proteins ThiG and D-amino acid dehydrogenase small subunits from Escherichia coli, respectively; Method: conceptual translation supplied by author; ORF656 [Synechocystis sp.] Length = 656 Score = 78.8 bits (191), Expect = 1e-13 Identities = 90/354 (25%), Positives = 151/354 (42%), Gaps = 29/354 (8%) Query: 4 VIGGGIIGVATAYELAKLGE---EVVVFEKRYFGSGSTFRCASGIRAQFTDEAN----IK 56 +IGGGIIG+A A EL KL + +V V + + + S A+G+ A ++ + Sbjct: 9 IIGGGIIGLAIAVEL-KLKQKRLQVTVLSRDFAQAAS--HAAAGMLAPHAEQIAPGPMLD 65 Query: 57 LMKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPE 116 L S R+ E E+L + +TGY EA N + + + E Sbjct: 66 LCLASRWRYGEWVEKL-EQLTGMETGYNPCGILSPVFEAPHGNSSTNSAW------LDQE 118 Query: 117 EAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDGGRE 176 + P L E+ + G W+P+DG+ + A ++A + LGV+ V I Sbjct: 119 TIRYYQPGLG-EDVIGGWWHPDDGQVDNRKLVSALRQAAQSLGVQIQEGVTVQAIAQRHG 177 Query: 177 HKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTE-PLERGQIEP 235 + T +G F+ D V A +W + + P+ P K Q++ P Q P Sbjct: 178 QVTAVLTDQGSFQADSYVLANGSWAKELLPL------PVFPVKGQMMALRMPAGTHQPYP 231 Query: 236 LVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHV 295 L +Y++ DG +I G E TP ++ +L A+++ PAL Sbjct: 232 LQRVLFGPQTYLV-PRRDGRLIVGATSEQVDWQPHNTP--QGIQTLLGRAIRLFPALGDW 288 Query: 296 HVVRQWAGHYAKTPDNNPAIG-ELVEDFYVAIGFSGHGFMMAPAVAQALAERIV 348 + W G TPD P +G ++ +AIG +G ++AP A +++ I+ Sbjct: 289 AIEDFWWGFRPGTPDEQPFLGYGPCDNLILAIGHYRNGILLAPITAALISDLIL 342 >sp|P44732|ORDL_HAEIN PROBABLE OXIDOREDUCTASE ORDL >gi|1073832|pir||F64072 probable oxidoreductase (EC 1.-.-.-) HI0499 - Haemophilus influenzae (strain Rd KW20) >gi|1573476|gb|AAC22156.1| (U32731) oxidoreductase, putative [Haemophilus influenzae Rd] Length = 431 Score = 76.9 bits (186), Expect = 4e-13 Identities = 91/378 (24%), Positives = 159/378 (41%), Gaps = 58/378 (15%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRA-------------QFT 50 VIG G G++ A ELA+ G++V+V E G G++ R SG +A Q Sbjct: 37 VIGAGFFGLSAALELAEKGKKVIVLEGARVGFGASGR--SGGQAINGFEEGIDEYIKQVG 94 Query: 51 DEANIKLMKYSIERWKELSEELG-HNIMFQ-QTGYLFLATTEEEVEAFKKNIKLQNR-FG 107 ++ KL S+E + E + ++I + GY LA E ++ + K ++ FG Sbjct: 95 EDKAHKLWNMSLETIDIIDERIEKYSIQCDWKKGYATLALNERRMDDLIEMEKESHKNFG 154 Query: 108 VPTKLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFY---P 164 + + ++ L + ++ G ++ G P + KA LGV+ + P Sbjct: 155 YQNMQLW--DKTKLKQHLGSDIYVGGLFDSNSGHLHPLNYCLGLAKACVDLGVQIFEQSP 212 Query: 165 YTEVVWIDGGREHKWKIKTTKGEFEVDVIVNATNAW----GSRINSMIGKDIVPITPFKH 220 ++V +G E +KT K ++ ATNA+ I+ I + I+P+ F Sbjct: 213 VVDMVEKNGCVE----VKTAKSAVISQDVILATNAYIDVLPKSIHHGINRKILPVESF-- 266 Query: 221 QLVKTEPLERGQIEPLVCPPAWNDSYVIQDGEDGGVICGTAL---EYKSDPD-------D 270 ++ TEPL + + ++ +G +C L Y+ D D Sbjct: 267 -IIATEPLSQAVADSVI--------------NNGMSVCDNNLLLDYYRLSADNRLLFGSD 311 Query: 271 VTPTYDFVKEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSG 330 + D V + K + + P L +V + WAG T ++ P G + Y A G+SG Sbjct: 312 SSSEKDMVAIMRKNMLCVFPQLENVKIDYGWAGPIDMTLNSTPHFGRISPHIYFAHGYSG 371 Query: 331 HGFMMAPAVAQALAERIV 348 HG + + +AE I+ Sbjct: 372 HGVALTGLAGRIVAEAIL 389 >sp|O32159|YURR_BACSU HYPOTHETICAL 39.4 KD OXIDOREDUCTASE IN HOM-MRGA INTERGENIC REGION >gi|7475684|pir||A70019 opine catabolism homolog yurR - Bacillus subtilis >gi|2635760|emb|CAB15253.1| (Z99120) similar to opine catabolism [Bacillus subtilis] Length = 372 Score = 76.1 bits (184), Expect = 6e-13 Identities = 94/379 (24%), Positives = 158/379 (40%), Gaps = 36/379 (9%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGI----RAQFTDEANIKLMK 59 ++G GI+G +TAY LAK G V V +++ G + A+GI +Q ++ +L K Sbjct: 6 IVGAGILGASTAYHLAKTGARVTVIDRKEPGQATD--AAAGIVCPWLSQRRNQDWYQLAK 63 Query: 60 YSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNR----------FGVP 109 +K+L +L + TGY + +A K + K++ R G Sbjct: 64 GGARYYKDLIHQLEKD-GESDTGYKRVGAISIHTDASKLD-KMEERAYKRREDAPEIGDI 121 Query: 110 TKLITPEEAKEIVPPL--NVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTE 167 T+L + E K++ P L E +G+A + A EK G Sbjct: 122 TRL-SASETKKLFPILADGYESVHISGAARVNGRA----LCRSLLSAAEKRGATVIKGNA 176 Query: 168 VVWIDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEP 227 + + G ++T +F D ++ AW + I +G ++ K Q++ E Sbjct: 177 SLLFENGT--VTGVQTDTKQFAADAVIVTAGAWANEILKPLGIHF-QVSFQKAQIMHFEM 233 Query: 228 LERGQIE-PLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAV 286 + P+V PP +D Y++ ++G ++ G E + DD+ T EVL A+ Sbjct: 234 TDADTGSWPVVMPP--SDQYIL-SFDNGRIVAGATHENDAGLDDLRVTAGGQHEVLSKAL 290 Query: 287 KIIPALRHVHVVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHGFMMAPAVAQALA 344 + P L V G TP P +G + V+ Y A G G M P + LA Sbjct: 291 AVAPGLADAAAVETRVGFRPFTPGFLPVVGAVPNVQGLYAANGLGASGLTMGPFLGAELA 350 Query: 345 ERIVKGRTKVPLDWEWYDP 363 + ++ +T+ LD YDP Sbjct: 351 KLVLGKQTE--LDLSPYDP 367 >pir||B75218 glycerol-3-phosphate dehydrogenase (glpa) PAB0183 - Pyrococcus abyssi (strain Orsay) >gi|5457702|emb|CAB49193.1| (AJ248283) glycerol-3-phosphate dehydrogenase (glpA) [Pyrococcus abyssi] Length = 497 Score = 75.3 bits (182), Expect = 1e-12 Identities = 95/378 (25%), Positives = 160/378 (42%), Gaps = 17/378 (4%) Query: 2 IGVIGGGIIGVATAYELAKLGE-EVVVFEKRY-FGSGSTFRCASGIRAQFTDEANIKLMK 59 + +IG GI G + A L+K EV + EK G G + + I + D+ M+ Sbjct: 7 VAIIGAGITGASIARVLSKYENLEVHLIEKNPDVGWGVSKANTAIIHGGYDDDPEKYPMR 66 Query: 60 YSI-----ERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPT-KLI 113 W E ++L I G L +A EE+ + +K ++ + GVP +++ Sbjct: 67 ARFCVKGNRIWHEWVKQL--EIPHVWNGALVVALEEEDFDELEKLLERGIKNGVPEMRIV 124 Query: 114 TPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWIDG 173 EE ++ P LN L W P G+ +P + A + GVK + T+V I Sbjct: 125 DKEELFQLEPGLN-RNALGALWVPIVGQIAPIPAVIALVENAVANGVKTHLETKVKGIKV 183 Query: 174 GREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQL-VKTEPLERGQ 232 R ++T G E D+I+NA + I+ M+G D I P K + + E + + Sbjct: 184 KRGEVRGLETNDGFIEADIIINAAGLYADEISRMVGLDYFEIRPRKGEYWIFDEGIPGPK 243 Query: 233 IEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKS--DPDDVTPTYDFVKEVLKWAVKIIP 290 P + V+ G ++ G + S + ++ T + + EV + A K+ P Sbjct: 244 RVLFPTPTPISKGIVVTTEISGHLMIGPNAKDLSPEEKENTATTREGLDEVWEGAKKLWP 303 Query: 291 AL-RHVHVVRQWAGHYAKTPDNNPAI--GELVEDFYVAIGFSGHGFMMAPAVAQALAERI 347 L V+R +AG + + I E V F G G APA+A +AE I Sbjct: 304 NLPPRSKVIRTFAGLRPEPTGGDFIIRAEEEVWGFINVAGIRSPGLTSAPAIAYYVAELI 363 Query: 348 VKGRTKVPLDWEWYDPYR 365 + ++ + ++PYR Sbjct: 364 ERELDVKLIEKKNWNPYR 381 >sp|P37906|ORDL_ECOLI PROBABLE OXIDOREDUCTASE ORDL >gi|7449558|pir||H64878 probable oxidoreductase (EC 1.-.-.-) ordL - Escherichia coli >gi|1054921|gb|AAC45300.1| (U38543) oxidoreductase [Escherichia coli] >gi|1742131|dbj|BAA14870.1| (D90768) Probable oxidoreductase OrdL (EC 1.-.-.-). [Escherichia coli] >gi|1787559|gb|AAC74383.1| (AE000228) probable oxidoreductase [Escherichia coli K12] Length = 426 Score = 74.1 bits (179), Expect = 2e-12 Identities = 79/367 (21%), Positives = 150/367 (40%), Gaps = 43/367 (11%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIE 63 V+GGG G+++A LA+ G +VVV E G G++ R + ++ + ++ Y ++ Sbjct: 32 VVGGGYTGLSSALHLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRDIDVIEKSYGMD 91 Query: 64 RWKELSEEL--GHNIMFQQT-----------GYLFLATTEEEVEAFKKNIKLQNRFGVPT 110 + L + G I+ ++ G LF+A ++++ ++ + R+G Sbjct: 92 TARMLGSMMFEGGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYG--N 149 Query: 111 KLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVW 170 K + +A I + + + + G P + A G + Y + V Sbjct: 150 KQLELLDANAIRREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQ 209 Query: 171 IDGGREHKWKIKTTKGEFEVDVIVNATNAW-GSRINSMIGKDIVPITPFKHQLVKTEPLE 229 I ++T KG+ ++ A NA+ G ++ + K +P Q++ TE L Sbjct: 210 IQ--HTTPAVVRTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGT---QVITTERLS 264 Query: 230 RGQIEPLVCPPAWNDSYVIQDGE----------DGGVICGTALEYKS-DPDDVTPTYDFV 278 L+ +Y ++D D ++ G + Y + DPDDV Sbjct: 265 EDLARSLI-----PKNYCVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVE------ 313 Query: 279 KEVLKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPA 338 + V+ +K P L+ V + +W G++ T P G L + Y G+SGHG Sbjct: 314 RLVVPKLLKTFPQLKGVKIDYRWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHL 373 Query: 339 VAQALAE 345 + +AE Sbjct: 374 AGRLIAE 380 >dbj|BAB09014.1| (AB007645) contains similarity to unknown protein~gene_id:K8K14.1~sp|Q10058 [Arabidopsis thaliana] Length = 406 Score = 73.4 bits (177), Expect = 4e-12 Identities = 99/386 (25%), Positives = 151/386 (38%), Gaps = 46/386 (11%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANI-KLMKYSI 62 V GGG+IGV TAY LAK G V + EK ++ + + + D + + L + S Sbjct: 44 VCGGGVIGVCTAYFLAKKGIAVTLVEKSAVACAASGKAGGFLAFDWCDGSPVAHLARASF 103 Query: 63 ERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTK----LITPEEA 118 + + L+EEL + L+ T E + + L + P K + T + Sbjct: 104 KLHRSLAEELNGVESYGYRALTTLSVTVTESKPGSGGLGLPDWVNGPAKSTSTIGTTQTT 163 Query: 119 KEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVK-FYPYTEVVWIDGGREH 177 ++ P L + L+ A EK GV+ E V ++ GR + Sbjct: 164 AQVHPQLFTRKLLS--------------------TAREKYGVEVVIGKLEEVRVESGRVN 203 Query: 178 KWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERGQIEP-- 235 ++ + + DV+V A W S+ + I + K + EP E I P Sbjct: 204 SVVLEGGR-VIDTDVVVLAMGPWSSKFELL--SSIFRVYCTKAHSIVLEPKEPNAITPHA 260 Query: 236 --LVCPPAWN----DSYVIQDGEDGGVICGTAL--EYKSDPDDVTPTYDFVKEVLKWAVK 287 L PA D V ICG + E D D VT + + +VLK K Sbjct: 261 LFLTYRPAHGGEALDPEVYPRPTGEVYICGMSSQEEVPDDADQVTSNPESI-QVLKRVAK 319 Query: 288 IIPAL---RHVHVVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHGFMMAPAVAQA 342 + + + V + A T D P IGE+ ++ YV G S G + PA A Sbjct: 320 TVSSYLNEENALVKAEQACFLPSTEDGVPVIGEIPGIKGCYVGTGHSCWGILNGPATGAA 379 Query: 343 LAERIVKGRTKVPLDWEWYDPYRFER 368 LAE IV G +D + P RF + Sbjct: 380 LAELIVDG-VATSVDLSRFSPSRFSK 404 >emb|CAC11772.1| (AL445064) glycerol-3-phosphate dehydrogenase related protein [Thermoplasma acidophilum] Length = 422 Score = 71.4 bits (172), Expect = 2e-11 Identities = 96/370 (25%), Positives = 153/370 (40%), Gaps = 40/370 (10%) Query: 2 IGVIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFR----CASGIRAQFTDEANIKL 57 I VIG GI G+ AY LA G +V VFE+ SG++ R SG R DE + + Sbjct: 8 IAVIGAGINGIFAAYYLAYAGYDVTVFERGDIDSGTSGRFHGMLHSGARYATNDEVSARE 67 Query: 58 MKYSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEE 117 R +GH + + TG FLA ++E E R G+ I EE Sbjct: 68 CIVENRR----ISNIGHRYV-ENTGGYFLAANDDEAEFGDVLFDACRRAGIDISEIPIEE 122 Query: 118 AKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWID----- 172 P L + A D + + + A +G K Y++V ID Sbjct: 123 FARDNPQL---KNARRAMRVPDKVIRSYEFVVSVAAAAHLMGTKIRTYSDVKKIDIEGNS 179 Query: 173 -GGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLERG 231 G E++ K +F D +VNAT + +I G P+ P +V E Sbjct: 180 VTGIEYERSGKEISEKF--DAVVNATGPFSGKILERSGLKQTPVMPSAGIMVVLEGRVST 237 Query: 232 QI-----EPL---VCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLK 283 I EP + P W++S + V+ ++ +P+D+ D + E++ Sbjct: 238 AILNRMREPSDADILLPYWSNSIL----GTSAVVVEDPDSFRPEPEDMQMMIDDMSELVP 293 Query: 284 WAVKIIPALRHVHVVR---QWAGHYAKTPDNNPAI--GELVEDFYVAIGFSGHGFMMAPA 338 AVKI+P R+ + VR + AG A+T + I E ++D +++ G F Sbjct: 294 -AVKIMPIKRYYYSVRPLIEDAGEDARTASRSFRIVGEEDLDDTLLSV--VGGKFTTGRL 350 Query: 339 VAQALAERIV 348 V + +A+R++ Sbjct: 351 VGEEIAKRVM 360 >pir||G81179 oxidoreductase, probable NMB0614 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7225844|gb|AAF41041.1| (AE002416) oxidoreductase, putative [Neisseria meningitidis MC58] Length = 431 Score = 71.0 bits (171), Expect = 2e-11 Identities = 82/366 (22%), Positives = 151/366 (40%), Gaps = 33/366 (9%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSG----------STFRCASG-IRAQFTDE 52 +IGGG+ G+ TA LA+ G E VV E G G S + C G I Q E Sbjct: 37 IIGGGLGGLCTALPLAEQGHETVVLEAARIGFGASGRSGGQVISDYACGMGEIEKQVGLE 96 Query: 53 ANIKLMKYSIERWKELSEELGHNIMF--QQTGYLFLATTEEEVEAFKK-NIKLQNRFGVP 109 + S++ + + E + + + Q GY +A + E ++ + Q +G Sbjct: 97 QAQWFWQQSLQAVELVDERVRKHAVDCDWQRGYATVAVRPQHWEELQQWHEHAQRHYGAS 156 Query: 110 TKLITPEEAKEIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVV 169 + + E+ L+ + + ++P G P +A + G + + + + Sbjct: 157 HYQLW--DKAELKQQLDSDMYQGAQFDPLSGHLHPLTYTLGIARAAAEAGAQIFEQSPMT 214 Query: 170 WIDGGREHKWKIKTTKGEFEVDVIVNATNAWG--SRINSMIGKDIVPITPFKHQLVKTEP 227 I+ ++ W + T +G E +V A N + + I + + + ++ F ++ TEP Sbjct: 215 CIEP-HQNGWLVYTPEGSVECKNVVYAVNTYAGLNPIFRPLERKAIAVSTF---IIATEP 270 Query: 228 L---ERGQIEP--LVCPPAWNDSYVIQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVL 282 L +G I VC Y + + G E+ +P+ +T + V++ + Sbjct: 271 LGARAKGLIRNNMAVCDNRHILDYYRLSADGRLLFGGKDNEFIDNPERMT---ELVRQDM 327 Query: 283 KWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGELVEDFYVAIGFSGHGFMMAPAVAQA 342 +K+ P L V + W G T + P G L + + A G+SGHG + A Sbjct: 328 ---LKVFPQLADVKIEYSWGGECDITANLVPHFGRLAPNVFYAQGYSGHGMAITGIAGLA 384 Query: 343 LAERIV 348 +AE I+ Sbjct: 385 VAEAIL 390 >pir||B83078 probable D-amino acid oxidase PA4548 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950792|gb|AAG07936.1|AE004868_7 (AE004868) probable D-amino acid oxidase [Pseudomonas aeruginosa] Length = 364 Score = 71.0 bits (171), Expect = 2e-11 Identities = 86/375 (22%), Positives = 161/375 (42%), Gaps = 53/375 (14%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFT---DEANIKLMKY 60 V+G G+IG+ TA ELA G V + E+ G +++ + + A L + Sbjct: 7 VVGAGVIGLLTARELALAGLRVTLVERGESGREASWAGGGIVSPLYPWRYSPAVTALAHW 66 Query: 61 SIERWKELSEELGHNIMFQQTGY--------LFLATTEEEVEAFKKNIKLQNRFGVPTKL 112 S + + L + L +TG L+ +++ EA ++ + P K Sbjct: 67 SQDFYPALGQRL-----LDETGLDPEVHTVGLYWLDLDDQTEA----LQWARKHTRPLKE 117 Query: 113 ITPEEAKEIVPPLNV----EEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEV 168 + EEA VP L +++G N + + + +L A + L + + TEV Sbjct: 118 VPIEEAYAAVPGLGAGFQRAVYMSGVANVRNPRLA--RSLRASLQQFANL--ELHEQTEV 173 Query: 169 V-WIDGGREHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEP 227 W+ G + + T++GE D ++ A AW + +G ++ P+ P K Q++ + Sbjct: 174 RGWLRDG-DRVVGVATSRGEIRGDKVLLAAGAWSGELLKPLGLEL-PVVPVKGQMILYK- 230 Query: 228 LERGQIEPLVCPPAWNDSYVIQDGE------DGGVICGTALEYKSDPDDVTPTYDFVKEV 281 C + V+ G DG ++ G+ LE+ D TPT + + + Sbjct: 231 ----------CAADFLPRMVLAKGRYAIPRRDGHILIGSTLEHSGF--DKTPTDEAQESL 278 Query: 282 LKWAVKIIPALRHVHVVRQWAGHYAKTPDNNPAIGEL--VEDFYVAIGFSGHGFMMAPAV 339 A +++P L + V WAG +P+ P IG + + ++ G +G ++APA Sbjct: 279 RASAAELLPELADMQPVAHWAGLRPGSPEGIPYIGPVPGFDGLWLNTGHYRNGLVLAPAS 338 Query: 340 AQALAERIVKGRTKV 354 + LA+ ++ GR + Sbjct: 339 CRLLAD-LMSGREPI 352 >pir||T35488 probable oxidoreductase - Streptomyces coelicolor (fragment) >gi|5689917|emb|CAB51955.1| (AL109661) putative oxidoreductase [Streptomyces coelicolor A3(2)] Length = 375 Score = 70.2 bits (169), Expect = 4e-11 Identities = 81/355 (22%), Positives = 147/355 (40%), Gaps = 18/355 (5%) Query: 9 IIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTD-----EANIKLMKYSIE 63 IIG+ TA+ A+ G + + G + A+G+ A T+ E + L S Sbjct: 1 IIGLVTAWRAARRGLVTALVDPE--PGGGAAQVAAGMLAAVTELHYGEETLLALNLASAR 58 Query: 64 RWKELSEEL----GHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAK 119 R+ E + EL GH++ +++ G L +A ++ ++ LQ R G+ ++ ++ E + Sbjct: 59 RYPEFAAELTELTGHDLGYRRCGTLAVALDADDRAHLRELHALQQRSGLESEWLSGRECR 118 Query: 120 EIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYP-YTEVVWIDGGREHK 178 + P L G D + P A A E GV F+ + E + + G Sbjct: 119 RLEPML-APGVRGGLRVDGDHQIDPRRLARALVAACEHAGVVFHRVWAERLTVGRGDRAT 177 Query: 179 WKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVK-TEPLERGQIEPLV 237 + E +V A + R+ + + P+ P K Q+++ T P G + Sbjct: 178 GVVGADGTALEAGQVVLAGGSLSGRLGGVPEAVLPPVRPVKGQVLRLTMPRTPGPLLNRT 237 Query: 238 CPPAWNDSYV-IQDGEDGGVICGTALEYKSDPDDVTPTYDFVKEVLKWAVKIIPALRHVH 296 ++V + E G ++ G E D T T V E+L+ A +++P + + Sbjct: 238 VRAVVRGNHVYLVPRESGELVVGATSEELGW--DTTVTAGGVYELLRDAHELVPGITELP 295 Query: 297 VVRQWAGHYAKTPDNNPAIGELVED-FYVAIGFSGHGFMMAPAVAQALAERIVKG 350 + AG +PDN P +G D +A G +G ++ P +AE + G Sbjct: 296 LTETRAGLRPGSPDNAPLLGPTALDGLLLATGHYRNGVLLTPVTGDVMAEALTGG 350 >sp|P43799|GLPA_HAEIN ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT A (G-3-P DEHYDROGENASE) >gi|1074156|pir||E64086 glycerol-3-phosphate dehydrogenase (EC 1.1.99.5) chain A, anaerobic - Haemophilus influenzae (strain Rd KW20) >gi|1573687|gb|AAC22345.1| (U32751) anaerobic glycerol-3-phosphate dehydrogenase, subunit A (glpA) [Haemophilus influenzae Rd] Length = 563 Score = 69.5 bits (167), Expect = 6e-11 Identities = 79/314 (25%), Positives = 134/314 (42%), Gaps = 27/314 (8%) Query: 4 VIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFR----CASGIRAQFTDEANIKLMK 59 +IGGG G A + A G + ++ E+R +G+T R SG R D+ + + Sbjct: 23 IIGGGATGAGIARDCALRGIDCILLERRDIATGATGRNHGLLHSGARYAVNDQES---AE 79 Query: 60 YSIERWKELSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNRFGVPTKLITPEEAK 119 I+ + L + H + +T LF+ E+ ++ K ++ + G+ + I PE AK Sbjct: 80 ECIKENRILRKIARHCV--DETEGLFITLPEDSLDYQKTFLESCAKSGIDAQAIDPELAK 137 Query: 120 EIVPPLNVEEFLAGAWNPEDGKASPFHTLYAYKKAGEKLGVKFYPYTEVVWI--DGGR-- 175 + P +N + L GA DG PF + + G K + Y EV + +GG+ Sbjct: 138 IMEPSVNPD--LVGAVVVPDGSIDPFRLTASNMMDATENGAKMFTYCEVKNLIREGGKVI 195 Query: 176 -----EHKWKIKTTKGEFEVDVIVNATNAWGSRINSMIGKDIVPITPFKHQLVKTEPLER 230 +HK + +F ++VNA WG I I LV + + Sbjct: 196 GVNAYDHK---NRRERQFFAPLVVNAGGIWGQGIAEYADLKIKMFPAKGALLVMGHRINK 252 Query: 231 GQIEPLVCPPAWNDSYVIQDGEDGGVICGTALEYKSDP-DDVTPTYDFVKEVLKWAVKII 289 I P D+ ++ G+ VI T+ D D++ T + V + + K+ Sbjct: 253 LVINRCRKPA---DADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDILFREGEKLA 309 Query: 290 PALRHVHVVRQWAG 303 P+LRH V+R +AG Sbjct: 310 PSLRHTRVLRAYAG 323 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.319 0.138 0.426 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 157706506 Number of Sequences: 2977 Number of extensions: 7134743 Number of successful extensions: 16181 Number of sequences better than 1.0e-10: 51 Number of HSP's better than 0.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 16044 Number of HSP's gapped (non-prelim): 57 length of query: 379 length of database: 189,106,746 effective HSP length: 53 effective length of query: 326 effective length of database: 157,386,935 effective search space: 51308140810 effective search space used: 51308140810 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 166 (69.1 bits)