BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0226 (THII) DE:THIAMIN BIOSYNTHESIS PROTEIN THII
         (198 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||B75149 thiamin biosynthesis protein thII PAB0226 - Pyrococc...   394  e-109
pir||B71189 hypothetical protein PH1786 - Pyrococcus horikoshii ...   326  1e-88
sp|Q58341|THII_METJA PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII...   171  5e-42
pir||T44564 probable thiamin biosynthesis protein thiI [imported...   151  5e-36
sp|O27720|THII_METTH PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII...   126  2e-28
gi|11498485 conserved hypothetical protein [Archaeoglobus fulgid...   111  8e-24
sp|Q9X220|THII_THEMA PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII...   104  6e-22
sp|O83570|THII_TREPA PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII...   103  1e-21
dbj|BAB06922.1| (AP001518) thiamin biosynthesis [Bacillus halodu...    97  2e-19
gb|AAK40666.1| Thiamine biosynthesis protein thiI (thiI) [Sulfol...    91  7e-18
sp|P47612|THII_MYCGE PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII...    90  1e-17
sp|O34595|THII_BACSU PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII...    90  2e-17
sp|P77718|THII_ECOLI THIAMINE BIOSYNTHESIS PROTEIN THII >gi|7467...    89  5e-17
sp|P55913|THII_SALTY THIAMINE BIOSYNTHESIS PROTEIN THII >gi|1135...    88  8e-17
pir||E82267 thiamin biosynthesis protein ThiI VC0894 [imported] ...    87  2e-16
pir||C82892 thiamin biosynthesis protein UU418 [imported] - Urea...    84  1e-15
emb|CAC11646.1| (AL445064) thiazole biosynthesis protein Thi I r...    84  1e-15
sp|Q9YEW8|THII_AERPE PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII...    82  5e-15
sp|P75228|THII_MYCPN PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII...    81  8e-15
gb|AAG19645.1| (AE005052) Vng1299c [Halobacterium sp. NRC-1]           79  4e-14
pir||F83005 thiazole biosynthesis protein ThiI PA5118 [imported]...    72  5e-12

>pir||B75149 thiamin biosynthesis protein thII PAB0226 - Pyrococcus abyssi
           (strain Orsay) >gi|5457783|emb|CAB49273.1| (AJ248284)
           THIAMIN BIOSYNTHESIS PROTEIN THII [Pyrococcus abyssi]
           Length = 198
           
 Score =  394 bits (1002), Expect = e-109
 Identities = 198/198 (100%), Positives = 198/198 (100%)

Query: 1   MKVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEIHGDKVKDP 60
           MKVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEIHGDKVKDP
Sbjct: 1   MKVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEIHGDKVKDP 60

Query: 61  RIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVAS 120
           RIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVAS
Sbjct: 61  RIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVAS 120

Query: 121 QTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVRA 180
           QTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVRA
Sbjct: 121 QTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVRA 180

Query: 181 GLGEFRKILNEVKDLLPK 198
           GLGEFRKILNEVKDLLPK
Sbjct: 181 GLGEFRKILNEVKDLLPK 198


>pir||B71189 hypothetical protein PH1786 - Pyrococcus horikoshii
           >gi|3258222|dbj|BAA30905.1| (AP000007) 201aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 201
           
 Score =  326 bits (827), Expect = 1e-88
 Identities = 152/198 (76%), Positives = 182/198 (91%)

Query: 1   MKVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEIHGDKVKDP 60
           M+V+ LLSSGIDSPVAIHL+AS+GAEVYPLHF+QD++KE K R++V RL+EIHG+KVKD 
Sbjct: 4   MRVIGLLSSGIDSPVAIHLMASRGAEVYPLHFRQDEIKEKKARKLVSRLKEIHGEKVKDL 63

Query: 61  RIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVAS 120
           ++VDA +VQGPVFEKLRE+++EKW CIFCKYTMY+VA  YARE+ A+AIVTGDSLGQVAS
Sbjct: 64  KVVDALKVQGPVFEKLRELKREKWICIFCKYTMYMVAEKYAREVGAEAIVTGDSLGQVAS 123

Query: 121 QTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVRA 180
           QTLDNLMV+STAT LPI+RPLIALDKEEIVRIAKEIGTF+IS E EPPCPF+P+FPVVRA
Sbjct: 124 QTLDNLMVISTATNLPIIRPLIALDKEEIVRIAKEIGTFEISIENEPPCPFLPKFPVVRA 183

Query: 181 GLGEFRKILNEVKDLLPK 198
           G  +FRKIL E++++LPK
Sbjct: 184 GFSQFRKILEEIREVLPK 201


>sp|Q58341|THII_METJA PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII >gi|2128072|pir||C64416
           conserved hypothetical MG372 related protein -
           Methanococcus jannaschii >gi|1591602|gb|AAB98933.1|
           (U67536) conserved hypothetical protein [Methanococcus
           jannaschii]
           Length = 381
           
 Score =  171 bits (429), Expect = 5e-42
 Identities = 95/192 (49%), Positives = 124/192 (64%), Gaps = 2/192 (1%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEIHGDKVKDPR 61
           KV+ L+S GIDSPVA  ++  +G     LH K  +   NKVR+IV+ L +   D   +  
Sbjct: 190 KVLCLISDGIDSPVAAFMMIRRGCRAVLLHLKMSEEALNKVRKIVEVLSDY--DTELEFV 247

Query: 62  IVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVASQ 121
           + D  +    + EKL+ I+KE +TCIFCK  M  VA  YA+ +   AIVTGD+LGQVASQ
Sbjct: 248 VYDYKKDIEDIVEKLKSIKKENYTCIFCKRKMLKVAEKYAKYLDCDAIVTGDNLGQVASQ 307

Query: 122 TLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVRAG 181
           TL NL V+S     PILRPLI LDK +IV+IAKEIGT++ISTEKE  CP++P+ P   A 
Sbjct: 308 TLKNLRVISENINYPILRPLIGLDKNDIVKIAKEIGTYEISTEKEIKCPYLPKHPKTIAK 367

Query: 182 LGEFRKILNEVK 193
             E +KI  +VK
Sbjct: 368 PEEVKKIKEKVK 379


>pir||T44564 probable thiamin biosynthesis protein thiI [imported] - Pyrococcus
           furiosus >gi|6066237|gb|AAF03222.1|AF156097_2 (AF156097)
           putative thiamine biosynthesis protein THII [Pyrococcus
           furiosus]
           Length = 363
           
 Score =  151 bits (378), Expect = 5e-36
 Identities = 88/196 (44%), Positives = 117/196 (58%), Gaps = 8/196 (4%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEIHGDKVKDPR 61
           KVVAL+S GIDSPVA  L+  +GAEV  LHF Q        +++V+++ EI  D   +P 
Sbjct: 167 KVVALISGGIDSPVAAFLMLKRGAEVIALHFDQG----TNAKKVVEKVVEILSDYSPEPI 222

Query: 62  ---IVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQV 118
              + + FE+  P    L +++K +WTCI CK  M   A   A+E  A  IVTGDSLGQV
Sbjct: 223 ELIVENHFEILKPYVSVLAKLQKREWTCILCKIAMLKRAAEIAKEEGALGIVTGDSLGQV 282

Query: 119 ASQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTE-KEPPCPFVPRFPV 177
           ASQTL NL + + + + PI RPLI  DKEEIV IAK IGT+D   E     CPF P   +
Sbjct: 283 ASQTLSNLFIETISVDYPIYRPLIGFDKEEIVSIAKRIGTYDAFLEYPYCECPFRPNRVI 342

Query: 178 VRAGLGEFRKILNEVK 193
            +  + EF  I +E++
Sbjct: 343 TQGKITEFYFIRDELR 358


>sp|O27720|THII_METTH PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII >gi|7429876|pir||C69092
           conserved hypothetical protein MTH1685 -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2622815|gb|AAB86157.1| (AE000926) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 389
           
 Score =  126 bits (314), Expect = 2e-28
 Identities = 77/179 (43%), Positives = 95/179 (53%), Gaps = 8/179 (4%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQ----DDVKENKVRRIVKRLQEIHGDKV 57
           KVVALLS GIDSPVA +L+  +G +V  +H        +  E KV +I  +L E      
Sbjct: 179 KVVALLSGGIDSPVATYLMMKRGCQVVAVHMDNAPFTGEEAEEKVEKIAAKLAEYSAGVE 238

Query: 58  KDPRIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQ 117
              R        G   E  R    EK TC+ CK+ MY +A   A E  A AIV G SLGQ
Sbjct: 239 FKLRTFS----YGRYLESCRRGAPEKMTCVLCKFGMYHLAEMVAEEEGALAIVDGSSLGQ 294

Query: 118 VASQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFP 176
           VASQTL N++       +PIL PLI +DK EI  +AK IGT+DIS   +  C  VP  P
Sbjct: 295 VASQTLPNILATRMGVNIPILSPLIGMDKVEIENLAKRIGTYDISVIPDGGCSAVPAHP 353


>gi|11498485 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|3915121|sp|O29382|THII_ARCFU PROBABLE THIAMINE
           BIOSYNTHESIS PROTEIN THII >gi|7429877|pir||G69359
           conserved hypothetical protein AF0879 - Archaeoglobus
           fulgidus >gi|2649723|gb|AAB90361.1| (AE001043) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 374
           
 Score =  111 bits (274), Expect = 8e-24
 Identities = 78/191 (40%), Positives = 109/191 (56%), Gaps = 10/191 (5%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEIHGD---KVK 58
           KVVAL+S GIDSPVA  +   +G EV  +HF    +   KVR  ++ L E   +   K+K
Sbjct: 167 KVVALISGGIDSPVAAFMAMKRGCEVVAVHFFNQTMHSPKVREKIRMLAEKLAEYQGKIK 226

Query: 59  DPRIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQV 118
              +V   EVQ  +  ++      K   +  + +M  +A   A +   KA+VTGDSL QV
Sbjct: 227 -LYMVPFKEVQFEIINRV----PPKLRMVVYRRSMMRMANLIAEKEGCKAVVTGDSLSQV 281

Query: 119 ASQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDIS-TEKEPPCPF-VPRFP 176
           ASQTLDN+ V+ +A++L +L PLI +DKEEIV IAK I T++IS    E  C F V + P
Sbjct: 282 ASQTLDNINVIYSASKLAVLPPLIGMDKEEIVAIAKRIETYEISILPYEDCCSFMVAQHP 341

Query: 177 VVRAGLGEFRK 187
             RA + +  K
Sbjct: 342 ETRAKIEDVVK 352


>sp|Q9X220|THII_THEMA PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII >gi|7445342|pir||H72223
           thiamin biosynthesis protein ThiI - Thermotoga maritima 
           (strain MSB8) >gi|4982270|gb|AAD36761.1|AE001809_13
           (AE001809) thiamin biosynthesis protein ThiI [Thermotoga
           maritima]
           Length = 388
           
 Score =  104 bits (258), Expect = 6e-22
 Identities = 72/200 (36%), Positives = 107/200 (53%), Gaps = 10/200 (5%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKEN----KVRRIVKRLQEIHGDKV 57
           K V LLS GIDSPVA      +G  +  + F            KVR I++ L+E  G   
Sbjct: 176 KAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHP 235

Query: 58  KDPRIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQ 117
               IV+  ++Q  V +++     +K++ I  + +M+ +A   A E  A A  TG+++GQ
Sbjct: 236 LRLHIVNLTKLQLEVKKRV----PDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQ 291

Query: 118 VASQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEK-EPPCP-FVPRF 175
           VASQTL+NL  + + T  P++RPL   DK EIV  AKEIGT++IS +  +  C  F P+ 
Sbjct: 292 VASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKN 351

Query: 176 PVVRAGLGEFRKILNEVKDL 195
           P  R+      K+  +V DL
Sbjct: 352 PATRSHPSILEKLEQQVPDL 371


>sp|O83570|THII_TREPA PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII >gi|7429878|pir||C71310
           conserved hypothetical protein TP0559 - syphilis
           spirochete >gi|3322853|gb|AAC26563.1| (AE001231)
           conserved hypothetical protein [Treponema pallidum]
           Length = 401
           
 Score =  103 bits (255), Expect = 1e-21
 Identities = 68/186 (36%), Positives = 101/186 (53%), Gaps = 8/186 (4%)

Query: 6   LLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEIHGDKVKDPR--IV 63
           LLS GIDSPVA + + S+G  +  L+F        + ++ V+ L ++           +V
Sbjct: 186 LLSGGIDSPVAGYRMLSRGMHIDCLYFHSYPYTPPEAQKKVEDLAKVLARYGLSTTLTVV 245

Query: 64  DAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVASQTL 123
              ++Q    ++L+         +  +  M  +A   ARE +A+ ++TG+SL QVASQTL
Sbjct: 246 SLTDIQ----KQLQTHAPAPSLTLLLRMCMMRIAEHVAREQRARCLITGESLAQVASQTL 301

Query: 124 DNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPC--PFVPRFPVVRAG 181
           +NL V S  T LPI RPLI  DKE+I+R A EIGT+ IS      C   F P+ PV+R  
Sbjct: 302 ENLTVTSACTHLPIFRPLIGADKEDIIRTATEIGTYAISIRPYEDCCTLFAPKHPVLRPE 361

Query: 182 LGEFRK 187
           + E +K
Sbjct: 362 VEEMQK 367


>dbj|BAB06922.1| (AP001518) thiamin biosynthesis [Bacillus halodurans]
           Length = 382
           
 Score = 96.7 bits (237), Expect = 2e-19
 Identities = 61/164 (37%), Positives = 91/164 (55%), Gaps = 8/164 (4%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEI---HGDKVK 58
           KV+ +LS GIDSPVA + +  +G  +  +HF        K ++ V  L       G +VK
Sbjct: 159 KVLLMLSGGIDSPVAGYYLLKRGVTLEAIHFHSPPFTNEKAKQKVVDLAAKLTNFGGQVK 218

Query: 59  DPRIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQV 118
              IV   E+Q  + EK+             +  M  ++   A++  A AI TG+SLGQV
Sbjct: 219 -LHIVPFTELQKHIHEKV----PSNMEMTIMRRMMLRISEGIAKKTDALAIATGESLGQV 273

Query: 119 ASQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDIS 162
           ASQTL ++  ++  T  P+LRPL+ +DKEE++ +AKEI TF+IS
Sbjct: 274 ASQTLHSMNTINEVTTTPVLRPLLTMDKEEVITVAKEIDTFNIS 317


>gb|AAK40666.1| Thiamine biosynthesis protein thiI (thiI) [Sulfolobus solfataricus]
           Length = 371
           
 Score = 91.3 bits (223), Expect = 7e-18
 Identities = 65/171 (38%), Positives = 91/171 (53%), Gaps = 10/171 (5%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQD-DVKENKVRRIVKRLQEIHGD-KVKD 59
           K V L S GIDSPVA  ++  +G+    L+F    D+ +  V + +  L+   G  K+K 
Sbjct: 170 KTVVLFSGGIDSPVATWMMMKRGSVPIILNFNLGGDLHKELVLKELNMLKRWSGGHKLK- 228

Query: 60  PRIVDAFEVQGP-VFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQV 118
                 F V+G  VF KL ++ +     +  K  MY  A     +  AK+I TG+SL QV
Sbjct: 229 -----IFIVKGTDVFIKLSQVERRS-RVVMLKRVMYKTAEKLCEKTNAKSITTGESLSQV 282

Query: 119 ASQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPC 169
           +SQT+ NL V     + PI RPLI  DKEEIV IA++IGT+  S +    C
Sbjct: 283 SSQTMANLYVTEYGIKYPIFRPLIGFDKEEIVDIARKIGTYKHSIKLPEYC 333


>sp|P47612|THII_MYCGE PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII >gi|1361675|pir||B64241
           hypothetical protein MG372 - Mycoplasma genitalium
           >gi|3844960|gb|AAC71599.1| (U39719) NTP-utilizing enzyme
           (GuaA family) [Mycoplasma genitalium]
           Length = 385
           
 Score = 90.5 bits (221), Expect = 1e-17
 Identities = 68/204 (33%), Positives = 107/204 (52%), Gaps = 12/204 (5%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENK-VRRIVKRLQEIHGDKVKDP 60
           K + LLS GIDSPVA  LV  +G  +  + F  +  K  K + +I +    I  +K    
Sbjct: 179 KALVLLSGGIDSPVAASLVMQRGFNIDFITFINEPNKNQKTIEKITRLANLISFNKTICS 238

Query: 61  RIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVAS 120
             +  F+    + ++L  I  E +  +  +   Y  A+ +    K   +VTG+ LGQVAS
Sbjct: 239 GKLLVFDFTA-IQKELIHISNESYRIVLMRRVFYKAASMF----KYDCLVTGEVLGQVAS 293

Query: 121 QTLDNLMVMSTAT-ELPILRPLIALDKEEIVRIAKEIGTFDISTEK--EPPCPFVPRFPV 177
           QT++NL V+ +AT +  I+RPLI   K++I+ +AK   TFDIS E+  +    F P+ P 
Sbjct: 294 QTIENLKVIQSATPDTFIVRPLIGFSKDKIIELAKFFNTFDISIEQHLDTCSEFSPKNPT 353

Query: 178 VRAGLGEFRKILNE---VKDLLPK 198
            +A L    K+ +E   + DL+ K
Sbjct: 354 TKAKLINVEKLESELIFLNDLIEK 377


>sp|O34595|THII_BACSU PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII >gi|7429879|pir||E69988
           conserved hypothetical protein ytbJ - Bacillus subtilis
           >gi|2293230|gb|AAC00308.1| (AF008220) YtbJ [Bacillus
           subtilis] >gi|2635442|emb|CAB14936.1| (Z99119) similar
           to hypothetical proteins [Bacillus subtilis]
           Length = 358
           
 Score = 89.7 bits (219), Expect = 2e-17
 Identities = 59/172 (34%), Positives = 88/172 (50%), Gaps = 10/172 (5%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQ----DDVKENKVRRIVKRLQEIHGDKV 57
           K + +LS G DSPVA      +G  V  +HF       +  + KV  + K L    G   
Sbjct: 179 KAMLMLSGGFDSPVAGFYAMKRGLSVEAVHFFSPPYTSERAKQKVMDLAKCLSRFGGSMT 238

Query: 58  KDPRIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQ 117
               IV   + Q    E +++   E +T    +  M  +A     +    AI+TG+SLGQ
Sbjct: 239 L--HIVPFTKTQ----ELIQKQIPENYTMTATRRLMLQIADRIREKRNGLAIITGESLGQ 292

Query: 118 VASQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPC 169
           VASQTL+++  ++  T  PILRPLIA+DK EI+  ++EIGT++ S +    C
Sbjct: 293 VASQTLESMYAINAVTSTPILRPLIAMDKTEIIEKSREIGTYETSIQPFEDC 344


>sp|P77718|THII_ECOLI THIAMINE BIOSYNTHESIS PROTEIN THII >gi|7467031|pir||G64771 yajK
           protein - Escherichia coli >gi|1773107|gb|AAB40179.1|
           (U82664) similar to M. jannaschii MG372 [Escherichia
           coli] >gi|1786625|gb|AAC73526.1| (AE000148) putative
           oxidoreductase [Escherichia coli K12]
           Length = 482
           
 Score = 88.5 bits (216), Expect = 5e-17
 Identities = 58/180 (32%), Positives = 95/180 (52%), Gaps = 6/180 (3%)

Query: 3   VVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVK-ENKVRRIVKRLQEIHGDKVKDPR 61
           V++L+S G DS V+ +++  +G  V+   F       E  VR++   L    G   +   
Sbjct: 180 VLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRF 239

Query: 62  IVDAFE-VQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVAS 120
           +   FE V G + EK+ + +      +  K  M   A+  A     +A+VTG++LGQV+S
Sbjct: 240 VAINFEPVVGEILEKIDDGQMG----VILKRMMVRAASKVAERYGVQALVTGEALGQVSS 295

Query: 121 QTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVRA 180
           QTL NL ++   ++  ILRPLI+ DKE I+ +A++IGT D +      C  + + P V+A
Sbjct: 296 QTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKA 355


>sp|P55913|THII_SALTY THIAMINE BIOSYNTHESIS PROTEIN THII >gi|11354259|pir||T46944 thiamin
           biosynthesis protein thiI [validated] - Salmonella
           typhimurium >gi|2098763|gb|AAB63031.1| (U94901) ThiI
           [Salmonella typhimurium]
           Length = 482
           
 Score = 87.8 bits (214), Expect = 8e-17
 Identities = 58/180 (32%), Positives = 95/180 (52%), Gaps = 6/180 (3%)

Query: 3   VVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVK-ENKVRRIVKRLQEIHGDKVKDPR 61
           V++L+S G DS V+ +++  +G  V+   F       E  VR++   L    G   +   
Sbjct: 180 VLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRF 239

Query: 62  IVDAFE-VQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVAS 120
           +   FE V G + EK+ + +      +  K  M   A+  A     +A+VTG++LGQV+S
Sbjct: 240 VAINFEPVVGEILEKVDDGQMG----VVLKRMMVRAASKVAERYGVQALVTGEALGQVSS 295

Query: 121 QTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVRA 180
           QTL NL ++   ++  ILRPLI+ DKE I+ +A++IGT D +      C  + + P V+A
Sbjct: 296 QTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKA 355


>pir||E82267 thiamin biosynthesis protein ThiI VC0894 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9655349|gb|AAF94056.1| (AE004173) thiamin
           biosynthesis protein ThiI [Vibrio cholerae]
           Length = 515
           
 Score = 86.6 bits (211), Expect = 2e-16
 Identities = 60/179 (33%), Positives = 93/179 (51%), Gaps = 4/179 (2%)

Query: 3   VVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDD-VKENKVRRIVKRLQEIHGDKVKDPR 61
           V++L+S G DS V+ +L   +G++V+   F       E  V++    L + +G   K   
Sbjct: 212 VLSLISGGFDSGVSSYLHIKRGSKVHYCFFNLGGPAHEIGVKQTAYYLWQKYGSSAKVRF 271

Query: 62  IVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVASQ 121
           I   F    PV  ++ E   +    +  K      A   A +   +A+VTG++LGQV+SQ
Sbjct: 272 IAIDF---APVVAEILEKIDDGQMGVVLKRMFMRTAGMVAEKFGIQALVTGEALGQVSSQ 328

Query: 122 TLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVRA 180
           TL NL  +   T+  ILRPLI  DKE+I+R+A+EIGT D +      C  + + P V+A
Sbjct: 329 TLTNLRHIDNVTDTLILRPLINWDKEDIIRLAREIGTEDFAKTMPEFCGVISKSPTVKA 387


>pir||C82892 thiamin biosynthesis protein UU418 [imported] - Ureaplasma
           urealyticum >gi|6899407|gb|AAF30829.1|AE002139_2
           (AE002139) thiamin biosynthesis protein [Ureaplasma
           urealyticum]
           Length = 390
           
 Score = 83.9 bits (204), Expect = 1e-15
 Identities = 61/199 (30%), Positives = 102/199 (50%), Gaps = 15/199 (7%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEV------YPLHFKQDDVKENKVRRIVKRLQEIHGD 55
           K + LLS GIDSPVA  L+  +G  +       P H  Q  +  +K   + K++   +  
Sbjct: 176 KALVLLSGGIDSPVASRLIMKRGISIDFITFITPPHTSQKAL--DKTIALAKQITLDNKL 233

Query: 56  KVKDPRIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSL 115
              +  + +  ++Q    +++  I KE +     +     +A   A  +KA A+VTG++L
Sbjct: 234 TKANLYVCNFTKLQ----DEIAHISKESYRITLMRRYFMRIAKRLAISVKANALVTGEAL 289

Query: 116 GQVASQTLDNLMVMSTATE-LPILRPLIALDKEEIVRIAKEIGTFDIS-TEKEPPCP-FV 172
           GQVASQTL+++  +S+  +   +LRPLIA DKEEI+ +AK   T+++S    +  C  F 
Sbjct: 290 GQVASQTLNSMQTISSVLDNFLVLRPLIAYDKEEIISLAKRFNTYELSILPYDDSCSLFA 349

Query: 173 PRFPVVRAGLGEFRKILNE 191
           P+ P     +    K+  E
Sbjct: 350 PKNPTTNPNVQTAAKLEEE 368


>emb|CAC11646.1| (AL445064) thiazole biosynthesis protein Thi I related protein
           [Thermoplasma acidophilum]
           Length = 469
           
 Score = 83.9 bits (204), Expect = 1e-15
 Identities = 63/190 (33%), Positives = 100/190 (52%), Gaps = 25/190 (13%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEV--------YPLHFKQ--DDVKENKVRRIVKRLQE 51
           K ++L+S GIDSPV+  ++  +G+          YP+  +   D VK+   R    R   
Sbjct: 158 KYISLVSGGIDSPVSTWMIMKRGSPCDILFCSLSYPVDLRPFVDVVKKLVERWAPYRKPR 217

Query: 52  IHGDKVKDPR-IVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIV 110
           I+   V D R ++    ++G          + K++ +  K  +Y +A   A E     IV
Sbjct: 218 IY---VADCRSLIRTMVIEG----------RTKYSNVTFKRVIYRIAEKIALENGYNGIV 264

Query: 111 TGDSLGQVASQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCP 170
           TG+SLGQV+SQT +NL  + +   +PILRPLI +DK+E+V +A+ IGTF   +  E    
Sbjct: 265 TGESLGQVSSQTAENLKAIESGIGVPILRPLIGMDKDEVVDMARRIGTFPELSMGEFCSL 324

Query: 171 FVPRFPVVRA 180
           F  R P++R+
Sbjct: 325 FASR-PIIRS 333


>sp|Q9YEW8|THII_AERPE PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII >gi|7445341|pir||H72741
           probable thiazole biosynthesis gene thi I APE0465 -
           Aeropyrum pernix (strain K1) >gi|5104112|dbj|BAA79428.1|
           (AP000059) 412aa long hypothetical thiazole biosynthesis
           gene thi I [Aeropyrum pernix]
           Length = 412
           
 Score = 81.9 bits (199), Expect = 5e-15
 Identities = 64/194 (32%), Positives = 103/194 (52%), Gaps = 7/194 (3%)

Query: 4   VALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDVKENKVRRIVKRLQEIHGDKVKD--PR 61
           +AL S G DS VA  ++  +G+ V+ L F    V E  +   V+  + + G+      PR
Sbjct: 198 LALYSGGFDSGVAAWMIMRRGSPVH-LAFYDFGVPE-ALEVAVEGAKTLAGEWAWGYRPR 255

Query: 62  IVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVASQ 121
           +      +G     +  + K  +  +  +  M + A   A     +A+VTG+S+GQVASQ
Sbjct: 256 LY-VVNFRGAALI-VNGLVKPSYRTLVLRRLMLLHAQDLAAREGFEALVTGESVGQVASQ 313

Query: 122 TLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVRAG 181
           T+ NL ++S+  ELP+LRPL  +DK+EIV  ++EIG +DI+  +   C  V + P  RA 
Sbjct: 314 TVRNLRLISSGLELPVLRPLAGMDKDEIVEKSREIGLYDIARRQVEVCG-VDQPPNPRAS 372

Query: 182 LGEFRKILNEVKDL 195
              FR    +V+D+
Sbjct: 373 PQGFRSEFEKVRDI 386


>sp|P75228|THII_MYCPN PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII >gi|2146443|pir||S73618
           MG372 homolog G12_orf387 - Mycoplasma pneumoniae (strain
           ATCC 29342) >gi|1673963|gb|AAB95940.1| (AE000027)
           Thiamin biosynthesis protein [Mycoplasma pneumoniae]
           Length = 387
           
 Score = 81.1 bits (197), Expect = 8e-15
 Identities = 62/199 (31%), Positives = 102/199 (51%), Gaps = 21/199 (10%)

Query: 4   VALLSSGIDSPVAIHLVASKGAEV-------YPLHFKQDDVKENKVRRIVKRLQEIHGDK 56
           +ALLS GIDSPVA  LV  +G  V        P H      K  ++  +V   Q +   +
Sbjct: 183 LALLSGGIDSPVAASLVLQRGFNVDFITFINEPGHNAATIGKIQRLANLVSLNQTLCTGR 242

Query: 57  VKDPRIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLG 116
           +    + D  ++Q    ++L  I  E +  +  +   Y +A+ +    K   ++TG++LG
Sbjct: 243 LF---VFDFTDLQ----KELSHISLEGYRIVLMRRCFYKIASLF----KYDCLITGEALG 291

Query: 117 QVASQTLDNL-MVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTE--KEPPCPFVP 173
           QVASQT+DNL ++ +      ++RPLI L K++I+  AK +GTF+ S E   +    F P
Sbjct: 292 QVASQTIDNLKVIQAVVPNTFVIRPLIGLSKDKIIEWAKALGTFETSIEHHMDTCTVFAP 351

Query: 174 RFPVVRAGLGEFRKILNEV 192
           + P  +A L    K+ +E+
Sbjct: 352 KKPTTKAKLAIVEKLESEL 370


>gb|AAG19645.1| (AE005052) Vng1299c [Halobacterium sp. NRC-1]
           Length = 392
           
 Score = 78.8 bits (191), Expect = 4e-14
 Identities = 62/188 (32%), Positives = 87/188 (45%), Gaps = 9/188 (4%)

Query: 3   VVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDDV----KENKVRRIVKRLQEIHGDKVK 58
           +VAL+S GIDSPVA      +GA V PL+    D        +    V+ L +   +   
Sbjct: 184 LVALVSGGIDSPVAAWESMRRGAPVIPLYLALGDYGGPDHRARAEAAVRTLDDYAPNHDL 243

Query: 59  DPRIVDAFEVQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQV 118
             R+  A    G   ++L           F ++ MY VA   A    A  IVTG+++GQ 
Sbjct: 244 SLRVAPA----GDAIDRLAAATGRTRMLSFRRF-MYRVAEHVAEHAGAAGIVTGEAVGQK 298

Query: 119 ASQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVV 178
           +SQT  NL V+  AT LP+ RPL+  DK+ I   A+ I TF  S+         PR P+ 
Sbjct: 299 SSQTTANLGVVDRATTLPVHRPLLTWDKQRITAAARSIDTFRDSSLDVGCNRLAPRQPLT 358

Query: 179 RAGLGEFR 186
            A +   R
Sbjct: 359 AAPIESVR 366


>pir||F83005 thiazole biosynthesis protein ThiI PA5118 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9951416|gb|AAG08503.1|AE004925_1 (AE004925) thiazole
           biosynthesis protein ThiI [Pseudomonas aeruginosa]
           Length = 484
           
 Score = 71.8 bits (173), Expect = 5e-12
 Identities = 52/181 (28%), Positives = 89/181 (48%), Gaps = 6/181 (3%)

Query: 2   KVVALLSSGIDSPVAIHLVASKGAEVYPLHFKQDD-VKENKVRRIVKRLQEIHGDKVKDP 60
           +V+ L+S G DS VA + +  +G   + + F       E  V  +   L E +G   +  
Sbjct: 181 QVLVLMSGGFDSTVAAYQMMRRGMISHFVFFNLGGRAHELGVMEVAHYLWEKYGRSQRVL 240

Query: 61  RIVDAFE-VQGPVFEKLREIRKEKWTCIFCKYTMYIVATSYAREIKAKAIVTGDSLGQVA 119
            +   FE V G +  K+     + +  +  K  M   A+  A  ++  A+VTG+++ QV+
Sbjct: 241 FVSVPFEEVVGEILTKV----DDSYMGVTLKRMMLRAASRVAERLELDALVTGEAISQVS 296

Query: 120 SQTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFDISTEKEPPCPFVPRFPVVR 179
           SQTL NL V+   T+  +LRPLI   K++I+  A++IGT + +      C  +   P  +
Sbjct: 297 SQTLPNLSVIDRVTDTLVLRPLIVSHKQDIIDTARQIGTAEFARHMPEYCGVISVNPTTQ 356

Query: 180 A 180
           A
Sbjct: 357 A 357


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.321    0.139    0.395 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68120407
Number of Sequences: 2977
Number of extensions: 2617130
Number of successful extensions: 8659
Number of sequences better than 1.0e-10: 21
Number of HSP's better than  0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 8626
Number of HSP's gapped (non-prelim): 21
length of query: 198
length of database: 189,106,746
effective HSP length: 55
effective length of query: 143
effective length of database: 156,189,961
effective search space: 22335164423
effective search space used: 22335164423
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 163 (67.9 bits)