BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0231 (pyrG) DE:CTP synthase (pyrG)
(537 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||F75149 CTP synthase (pyrg) PAB0231 - Pyrococcus abyssi (str... 1083 0.0
pir||H71189 probable CTP synthase - Pyrococcus horikoshii >gi|32... 1047 0.0
gi|11497868 CTP synthase (pyrG) [Archaeoglobus fulgidus] >gi|743... 670 0.0
sp|Q58574|PYRG_METJA CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 663 0.0
sp|P13242|PYRG_BACSU CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 639 0.0
pir||F70415 CTP synthetase - Aquifex aeolicus >gi|2983754|gb|AAC... 636 0.0
pir||G72539 probable CTP synthetase APE1604 - Aeropyrum pernix (... 633 e-180
gb|AAG20038.1| (AE005084) CTP synthase; PyrG [Halobacterium sp. ... 629 e-179
gb|AAK40547.1| CTP synthetase (UTP-ammonia lyase) (pyrG) [Sulfol... 629 e-179
dbj|BAB07511.1| (AP001520) CTP synthetase [Bacillus halodurans] 629 e-179
sp|Q54775|PYRG_SYNP7 CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 621 e-177
sp|P74208|PYRG_SYNY3 CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 608 e-173
emb|CAC11192.1| (AL445063) probable CTP synthase [Thermoplasma a... 605 e-172
pir||B83192 CTP synthase PA3637 [imported] - Pseudomonas aerugin... 603 e-171
pir||E69154 CTP synthase - Methanobacterium thermoautotrophicum ... 597 e-170
pir||F81798 CTP synthase (EC 6.3.4.2) NMA1742 [imported] - Neiss... 591 e-168
pir||F81070 CTP synthase NMB1554 [imported] - Neisseria meningit... 590 e-167
pir||B75379 CTP synthase - Deinococcus radiodurans (strain R1) >... 587 e-166
pir||E82074 CTP synthase VC2448 [imported] - Vibrio cholerae (gr... 583 e-165
sp|P44341|PYRG_HAEIN CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 575 e-163
dbj|BAB00835.1| (AB024033) CTP synthase [Arabidopsis thaliana] >... 575 e-163
gb|AAA24485.1| (M12843) CTP synthetase (EC 6.3.4.2) [Escherichia... 572 e-162
sp|P08398|PYRG_ECOLI CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 571 e-162
emb|CAA09021.2| (AJ010153) CTP synthetase [Lactococcus lactis su... 569 e-161
sp|P57491|PYRG_BUCAI CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 568 e-161
pir||C82700 CTP synthetase XF1288 [imported] - Xylella fastidios... 567 e-160
pir||T36879 probable CTP synthetase - Streptomyces coelicolor >g... 550 e-155
pir||T05340 CTP synthase (EC 6.3.4.2) F1C12.230 - Arabidopsis th... 542 e-153
sp|P28595|PYRG_AZOBR CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 539 e-152
sp|P52200|PYRG_SPICI CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 538 e-152
pir||T01513 CTP synthase (EC 6.3.4.2) T10M13.13 - Arabidopsis th... 536 e-151
pir||T00471 CTP synthase (EC 6.3.4.2) F19I3.12 - Arabidopsis tha... 533 e-150
gi|4503133 CTP synthase; Cytidine 5'-triphosphate synthetase; cy... 532 e-150
gb|AAD32937.1|AC004135_12 (AC004135) T17H7.12 [Arabidopsis thali... 531 e-150
gi|9055198 CTP synthetase homolog [Mus musculus] >gi|1654186|gb|... 529 e-149
gi|7949029 CTP synthase [Mus musculus] >gi|2494763|sp|P70698|PYR... 529 e-149
dbj|BAB14814.1| (AK024070) unnamed protein product [Homo sapiens] 529 e-149
gi|9789919 CTP synthase II; CTP synthetase type 2 [Homo sapiens]... 529 e-149
gb|AAC33441.1| (AF061753) CTP synthase [Nitrosomonas europaea] 528 e-149
dbj|BAB14607.1| (AK023549) unnamed protein product [Homo sapiens] 525 e-148
sp|P96351|PYRG_MYCTU CTP SYNTHETASE (CTP SYNTHASE) (UTP--AMMONIA... 524 e-147
pir||F81418 CTP synthase (EC 6.3.4.2) Cj0027 [imported] - Campyl... 523 e-147
sp|Q9ZM99|PYRG_HELPJ CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 521 e-147
sp|Q59321|PYRG_CHLTR CTP SYNTHETASE (CTP SYNTHASE) (UTP--AMMONIA... 519 e-146
sp|O25116|PYRG_HELPY CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 519 e-146
gb|AAA80195.1| (U15192) CTP synthetase [Chlamydia trachomatis] 518 e-146
gb|AAF49665.1| (AE003532) CG6854 gene product [alt 1] [Drosophil... 515 e-145
sp|P53529|PYRG_MYCLE CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 514 e-144
pir||B56447 CTP synthetase homolog - Chlamydia trachomatis 513 e-144
sp|O51522|PYRG_BORBU CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 511 e-144
pir||D81700 CTP synthase TC0455 [imported] - Chlamydia muridarum... 510 e-143
pir||T37497 probable CTP synthase - fission yeast (Schizosacchar... 508 e-143
gi|6319432 CTP synthase, highly homologus to URA8 CTP synthase; ... 503 e-141
pir||D72330 CTP synthetase - Thermotoga maritima (strain MSB8) >... 503 e-141
emb|CAA37941.1| (X53995) CTP synthetase [Saccharomyces cerevisiae] 499 e-140
pir||A72103 ctp synthetase - Chlamydophila pneumoniae (strain CW... 498 e-140
pir||E81568 CTP synthase CP0526 [imported] - Chlamydophila pneum... 498 e-140
gi|6322563 CTP synthase; Ura8p [Saccharomyces cerevisiae] >gi|10... 493 e-138
pir||C71342 probable CTP synthase (pyrG) - syphilis spirochete >... 491 e-138
sp|P38627|PYRH_YEAST CTP SYNTHASE 2 (UTP--AMMONIA LIGASE 2) (CTP... 484 e-136
pir||T43732 CTP synthase (EC 6.3.4.2) [imported] - Gibberella ze... 472 e-132
pir||C71695 ctp synthase (pyrG) RP378 - Rickettsia prowazekii >g... 470 e-131
emb|CAB95405.1| (AL359782) possible ctp synthase [Trypanosoma br... 458 e-128
gb|AAF49666.1| (AE003532) CG6854 gene product [alt 2] [Drosophil... 440 e-122
pir||T26252 hypothetical protein W06H3.3 - Caenorhabditis elegan... 439 e-122
gb|AAB41453.1| (U30328) cytidine triphosphate synthetase precurs... 438 e-122
sp|P50547|PYRG_CRIGR CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYN... 436 e-121
gb|AAC36385.1| (U51645) cytidine triphosphate synthetase [Plasmo... 354 2e-96
pir||B82910 CTP synthetase UU284 [imported] - Ureaplasma urealyt... 347 2e-94
pir||S48584 hypothetical protein - Mycoplasma capricolum (SGC3) ... 316 4e-85
gb|AAB35189.1| (S79193) CTP synthetase [Chinese hamsters, lung c... 265 1e-69
gb|AAB35190.1| (S79193) CTP synthetase [Chinese hamsters, lung c... 126 5e-28
dbj|BAB15204.1| (AK025654) unnamed protein product [Homo sapiens] 98 3e-19
pir||C83363 hypothetical protein PA2268 [imported] - Pseudomonas... 76 1e-12
emb|CAB71268.1| (AL138598) putative transferase. [Streptomyces c... 75 2e-12
>pir||F75149 CTP synthase (pyrg) PAB0231 - Pyrococcus abyssi (strain Orsay)
>gi|5457787|emb|CAB49277.1| (AJ248284) CTP synthase
(pyrG) [Pyrococcus abyssi]
Length = 537
Score = 1083 bits (2769), Expect = 0.0
Identities = 537/537 (100%), Positives = 537/537 (100%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF
Sbjct: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD
Sbjct: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR
Sbjct: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV
Sbjct: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL
Sbjct: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK 360
TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK
Sbjct: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK 360
Query: 361 IMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN 420
IMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN
Sbjct: 361 IMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN 420
Query: 421 LDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGI 480
LDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGI
Sbjct: 421 LDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGI 480
Query: 481 AGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEKDATH 537
AGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEKDATH
Sbjct: 481 AGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEKDATH 537
>pir||H71189 probable CTP synthase - Pyrococcus horikoshii
>gi|3258228|dbj|BAA30911.1| (AP000007) 557aa long
hypothetical CTP synthase [Pyrococcus horikoshii]
Length = 557
Score = 1047 bits (2679), Expect = 0.0
Identities = 514/537 (95%), Positives = 533/537 (98%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF
Sbjct: 21 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 80
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
VLDDGGEVDLDLGNYERFLDT+LTF+HNITTGKVYSTVIEKERRGEYLGATVQVIPHITD
Sbjct: 81 VLDDGGEVDLDLGNYERFLDTNLTFEHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 140
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
EIKRRIREIA++YDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKL+
Sbjct: 141 EIKRRIREIAKDYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLK 200
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEE ARKKISLFTNVP EAV+SAYDV
Sbjct: 201 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEEARKKISLFTNVPREAVVSAYDV 260
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
EDTYEVPLLLEREGLGKYL+KRL LEDREPDLREWEKMVAKYKAL+++VEIAIVGKYVKL
Sbjct: 261 EDTYEVPLLLEREGLGKYLIKRLKLEDREPDLREWEKMVAKYKALKETVEIAIVGKYVKL 320
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK 360
TDSYLSIKEALKHASVSN+VKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK
Sbjct: 321 TDSYLSIKEALKHASVSNDVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK 380
Query: 361 IMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN 420
IMTI+YARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN
Sbjct: 381 IMTIKYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN 440
Query: 421 LDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGI 480
L+KLGGTMRLGAYPVKIKKGTLAY LYKK+LVYERHRHRWEVNPDYIEAFEKAGLVFSG+
Sbjct: 441 LEKLGGTMRLGAYPVKIKKGTLAYRLYKKELVYERHRHRWEVNPDYIEAFEKAGLVFSGV 500
Query: 481 AGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEKDATH 537
AGDDERRMEILELPDKRYFIATQFHPEFKSRPM+PAPVFHGLV+AAKEYKQEK+AT+
Sbjct: 501 AGDDERRMEILELPDKRYFIATQFHPEFKSRPMRPAPVFHGLVRAAKEYKQEKNATN 557
>gi|11497868 CTP synthase (pyrG) [Archaeoglobus fulgidus]
>gi|7438008|pir||D69281 CTP synthase (pyrG) homolog -
Archaeoglobus fulgidus >gi|2650385|gb|AAB90978.1|
(AE001088) CTP synthase (pyrG) [Archaeoglobus fulgidus]
Length = 532
Score = 670 bits (1709), Expect = 0.0
Identities = 336/534 (62%), Positives = 409/534 (75%), Gaps = 6/534 (1%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+SGLGKGIT+ASIG L GY+ IKIDPYIN DAGTMNP+QHGEV+VL
Sbjct: 2 KYIVVTGGVMSGLGKGITAASIGRLFVDMGYRVIPIKIDPYINIDAGTMNPFQHGEVYVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DG EVDLDLG+YERF+ +T DHNITTGK+Y VIEKER+G+YLG TVQ+IPH+TDEI
Sbjct: 62 KDGTEVDLDLGHYERFIGEEVTGDHNITTGKIYKRVIEKERKGDYLGQTVQIIPHVTDEI 121
Query: 123 KRRIREIAR--NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
K IR +A+ N +I +VEIGGTVGDIE MPFLEA RQM EE E+ A VHVT VP L
Sbjct: 122 KSWIRRVAKESNAEICLVEIGGTVGDIEGMPFLEAIRQMHNEEKEEDFALVHVTLVP-LD 180
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
GEQKTKPTQHSVKELR LG+ PD IV R + L+ +KKI+LF +VPEEAVIS D
Sbjct: 181 AGGEQKTKPTQHSVKELRELGLHPDVIVGRCSERLKPATKKKIALFCDVPEEAVISNEDA 240
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
ED YEVPL+ +RE L +YL+++L L +E +EWE+MV + K L + IAIVGKYV +
Sbjct: 241 EDIYEVPLIFKREKLDEYLMRKLNLRAKE-SRKEWEEMVKRMKTLYEEASIAIVGKYVDV 299
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK 360
D+YLSIKEALKH + KV I W+++ED+E L+ VDGI+VPGGFGARGAEGK
Sbjct: 300 RDAYLSIKEALKHGGIEAGCKVNIVWVDSEDLENVDDFTLD-VDGILVPGGFGARGAEGK 358
Query: 361 IMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN 420
I I YAREN +PFLGICFGFQL V+EFARNV+G A+STE+D TP+PV+DL+PEQ+
Sbjct: 359 IRAIEYARENGVPFLGICFGFQLAVIEFARNVVGFSEANSTELDENTPHPVIDLLPEQKG 418
Query: 421 LDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGI 480
+D++GGTMRLG V IK GT+A++LY + V ERHRHR+EVNP+YIE E GLVFS
Sbjct: 419 IDEMGGTMRLGDIEVTIKPGTIAHKLYGSEKVVERHRHRYEVNPEYIEKIESKGLVFSAY 478
Query: 481 AGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEKD 534
+ D RRMEI ELPD +F ATQFHPEFKSRP +P+P F G V+AA +Y++E++
Sbjct: 479 S-DGGRRMEIAELPDHPFFFATQFHPEFKSRPYRPSPPFVGFVRAALKYRREEE 531
>sp|Q58574|PYRG_METJA CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|2118360|pir||E64446 CTP synthase (EC 6.3.4.2) -
Methanococcus jannaschii >gi|1591801|gb|AAB99177.1|
(U67559) CTP synthase (pyrG) [Methanococcus jannaschii]
Length = 540
Score = 663 bits (1691), Expect = 0.0
Identities = 327/531 (61%), Positives = 403/531 (75%), Gaps = 8/531 (1%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
KFIF+TGGV+S LGKGIT+AS+G L+KARG+K IKIDPY+ DAGTM+PY+HGEVFV
Sbjct: 5 KFIFITGGVISSLGKGITAASLGRLLKARGFKVNMIKIDPYLQIDAGTMSPYEHGEVFVT 64
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
+DGGE DLDLG+YERF+D +LT ++NITTGK+Y +V+ KER+GEYLG TVQVIPHIT+EI
Sbjct: 65 EDGGESDLDLGHYERFIDENLTKNNNITTGKIYWSVLTKERKGEYLGKTVQVIPHITNEI 124
Query: 123 KRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRVV 182
K I+ + YDI +VEIGGTVGDIES+PFLEA RQ + + G+ENV ++HV+ +P +R
Sbjct: 125 KDWIKNLGEGYDITIVEIGGTVGDIESLPFLEAIRQFKKDVGKENVLYIHVSLLPYIRAA 184
Query: 183 GEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVED 242
GE KTKPTQHSVKELRS+GIQPD ++ R+E P+ + R+K++LF +V +EAVI A D
Sbjct: 185 GELKTKPTQHSVKELRSIGIQPDILICRTEMPISDKIREKLALFCDVDKEAVIEARDART 244
Query: 243 TYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKLTD 302
YEVPL LE+EGLGK + K+L L DREPDL EW K V + + V I IVGKYV+L D
Sbjct: 245 IYEVPLNLEKEGLGKLVTKKLNLPDREPDLDEWRKFVDRVINPLNEVTIGIVGKYVELKD 304
Query: 303 SYLSIKEALKHASVSNEVKVKIRWIEAEDIE-EHGTKLLE------GVDGIIVPGGFGAR 355
+YLSI EAL HA N+ KV I WI +E +E E +LL+ +DGI+VPGGFG R
Sbjct: 305 AYLSITEALIHAGAKNDTKVNINWIHSERLESEEFEELLDRYREDNQLDGILVPGGFGDR 364
Query: 356 GAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLM 415
G EGKI I+YARENDIPFLGIC G Q V+EFARNV G++GA+STE D T YPVVDL+
Sbjct: 365 GVEGKINAIKYARENDIPFLGICMGMQCAVIEFARNVCGLEGANSTEFDENTKYPVVDLL 424
Query: 416 PEQRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGL 475
PEQ+ +D GGTMRLGAYP + +GTLAY+LY + VYERHRHR+EVNP+Y E E GL
Sbjct: 425 PEQKEIDAKGGTMRLGAYPAILMEGTLAYKLYGRKEVYERHRHRYEVNPEYHEILENHGL 484
Query: 476 VFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAA 526
SG D R E +E+ RYFIATQ HPEFKSRP KP P+F GLV+A+
Sbjct: 485 TISG-KSPDGRLAEFIEISKNRYFIATQAHPEFKSRPNKPHPLFDGLVRAS 534
>sp|P13242|PYRG_BACSU CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|68632|pir||SYBSTP CTP synthase (EC 6.3.4.2) -
Bacillus subtilis >gi|143597|gb|AAA16801.1| (M22039) CTP
synthetase [Bacillus subtilis]
>gi|853762|emb|CAA89870.1| (Z49782) CTP synthase
[Bacillus subtilis] >gi|2636252|emb|CAB15743.1| (Z99123)
CTP synthetase [Bacillus subtilis]
Length = 535
Score = 639 bits (1630), Expect = 0.0
Identities = 301/536 (56%), Positives = 406/536 (75%), Gaps = 4/536 (0%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
MTK+IFVTGGVVS LGKGI +AS+G L+K RG T K DPYIN D GTM+PYQHGEVF
Sbjct: 1 MTKYIFVTGGVVSSLGKGIVAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVF 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DDG E DLDLG+YERF+D +L N+TTGK+YSTV++KERRG+YLG TVQVIPHIT+
Sbjct: 61 VTDDGAETDLDLGHYERFIDINLNKFSNVTTGKIYSTVLKKERRGDYLGGTVQVIPHITN 120
Query: 121 EIKRRIREIAR--NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPK 178
E+K R+ + N D+V+ EIGGTVGDIES+PFLEA RQM+ + GRENV ++H T VP
Sbjct: 121 ELKDRVYRAGKETNADVVITEIGGTVGDIESLPFLEAIRQMKSDIGRENVMYIHCTLVPY 180
Query: 179 LRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAY 238
++ GE KTKPTQHSVKELRSLGIQP+ IV R+E P+ + + KI+LF ++ +AVI
Sbjct: 181 IKAAGELKTKPTQHSVKELRSLGIQPNIIVVRTEMPISQDMKDKIALFCDIDTKAVIECE 240
Query: 239 DVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYV 298
D ++ Y +PL L+++GL K + + + L +E ++ EW+++V K L ++ I +VGKYV
Sbjct: 241 DADNLYSIPLELQKQGLDKLVCEHMKLACKEAEMSEWKELVNKVSNLSQTITIGLVGKYV 300
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHG-TKLLEGVDGIIVPGGFGARGA 357
+L D+Y+S+ E+L+HA + + VK++WI AE++ E+ +L G DGIIVPGGFG RG
Sbjct: 301 ELPDAYISVVESLRHAGYAFDTDVKVKWINAEEVTENNIAELTSGTDGIIVPGGFGDRGV 360
Query: 358 EGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE 417
EGKI+ +YAREN+IPFLGIC G Q+ +E+ARNVLG+KGAHS EIDP T YP++DL+PE
Sbjct: 361 EGKIVATKYARENNIPFLGICLGMQVASIEYARNVLGLKGAHSAEIDPSTQYPIIDLLPE 420
Query: 418 QRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVF 477
Q++++ LGGT+RLG YP K+++GT A+E+Y+ ++VYERHRHR+E N ++ + E+ G VF
Sbjct: 421 QKDVEDLGGTLRLGLYPCKLEEGTKAFEVYQDEVVYERHRHRYEFNNEFRQQMEEQGFVF 480
Query: 478 SGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEK 533
SG D R +EI+EL D +F+A+QFHPEFKSRP +P P+F G + A+ E +K
Sbjct: 481 SG-TSPDGRLVEIIELKDHPWFVASQFHPEFKSRPTRPQPLFKGFIGASVEAANQK 535
>pir||F70415 CTP synthetase - Aquifex aeolicus >gi|2983754|gb|AAC07314.1|
(AE000735) CTP synthetase [Aquifex aeolicus]
Length = 531
Score = 636 bits (1622), Expect = 0.0
Identities = 300/532 (56%), Positives = 405/532 (75%), Gaps = 3/532 (0%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
M K+IF+TGGV+S LGKGITSASI +++ GY+ T K+DPY+N DAGTM+PYQHGEV+
Sbjct: 1 MAKYIFITGGVLSSLGKGITSASIASILEEMGYRVTLQKLDPYLNVDAGTMSPYQHGEVY 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V +DG E DLDLG+YERF + +T D+N+T G++Y VI KER+G+YLGATVQVIPHIT+
Sbjct: 61 VTEDGAETDLDLGHYERFTNAVMTRDNNVTAGRIYYNVISKERKGDYLGATVQVIPHITE 120
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
EIK I+ + ++ DIV+VEIGGTVGDIE +PFLEA RQ+ LE GR+N F+H+TYVP ++
Sbjct: 121 EIKESIKRVEKDNDIVIVEIGGTVGDIEGLPFLEAVRQLSLELGRKNSMFIHLTYVPYIK 180
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
GE KTKPTQHSVKELR++GIQPD I+ R++ L +G + KI+LFTNV EEAVISA D+
Sbjct: 181 AAGELKTKPTQHSVKELRAIGIQPDMIICRADRELPKGIKSKIALFTNVKEEAVISAPDL 240
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
E +YEVPL L+ +G+ + + +RL LE RE +L +W+K+V + ++ V +A+VGKYV+L
Sbjct: 241 EFSYEVPLKLKEQGIDRIITERLNLEHREVNLGKWKKIVNVLRNPEEEVNVALVGKYVEL 300
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK 360
DSY S+ EAL H ++N+VKV + +E ++ ++L E + GI+VPGGFG RG GK
Sbjct: 301 KDSYKSVIEALIHGGIANKVKVNVILKNSEQLDI--SELQEDIHGIMVPGGFGERGIRGK 358
Query: 361 IMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN 420
I + + REN+IP GIC G QL +EFARNVLG A+STE DP TP+PV+D+M EQ+
Sbjct: 359 IEALNFGRENNIPTFGICLGMQLMAIEFARNVLGFSNANSTEFDPDTPFPVIDIMEEQKK 418
Query: 421 LDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGI 480
+DKLGGTMRLGAYP K+K+ TLA+ +Y+KDL+YERHRHR+E N Y + FE G+VFSG
Sbjct: 419 VDKLGGTMRLGAYPCKVKENTLAHRIYQKDLIYERHRHRYEFNNRYRKDFESKGVVFSGT 478
Query: 481 AGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQE 532
+ DD + +EI+EL + +++ QFHPEFKS+P P P+F ++A EYK++
Sbjct: 479 SPDD-KLVEIMELKNHMWYLGCQFHPEFKSKPFAPHPLFRDFIRACLEYKRK 529
>pir||G72539 probable CTP synthetase APE1604 - Aeropyrum pernix (strain K1)
>gi|5105291|dbj|BAA80604.1| (AP000062) 538aa long
hypothetical CTP synthetase [Aeropyrum pernix]
Length = 538
Score = 633 bits (1614), Expect = e-180
Identities = 312/530 (58%), Positives = 396/530 (73%), Gaps = 9/530 (1%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ VTGGV+S +GKG+T+AS+ LL+ +RGY IKIDPYIN DAGTMNPY HGEVFV
Sbjct: 5 KYVIVTGGVLSSVGKGLTTASLALLLSSRGYSVEAIKIDPYINVDAGTMNPYMHGEVFVT 64
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
+DGGE DLD+G+YERFL +L+ HNITTG++Y +VI KER G+YLG TVQVIPHITDEI
Sbjct: 65 EDGGETDLDIGHYERFLGKNLSRKHNITTGQIYFSVISKERSGDYLGQTVQVIPHITDEI 124
Query: 123 KRRIREIA--RNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
K RI+E+ D+V+VEIGGTVGDIE +PFLEAARQM+LEEG +N F+HV P L
Sbjct: 125 KSRIKEVGDVSGADVVIVEIGGTVGDIEGLPFLEAARQMRLEEGFDNTFFIHVALSPYLP 184
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
GEQKTKP QHS++ELR +GIQPDA+V RS PLE+ +KI+L+ +P E VI++YD+
Sbjct: 185 TTGEQKTKPVQHSIQELRRIGIQPDAVVVRSHQPLEQEGLRKIALYATLPMENVINSYDI 244
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
E+ Y +PLLLE++GL + + +RL + PDL WE+ VA Y+ V++A+VGKY KL
Sbjct: 245 ENIYRLPLLLEKQGLARLVERRLFGRETRPDLSRWEEFVALYEKASRRVKVAMVGKYTKL 304
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEE---HGTKLLEGVDGIIVPGGFGARGA 357
DSY+SI EALKHAS V+ ++ W+E+ DIE ++ E DG IV GFG RG
Sbjct: 305 RDSYISIVEALKHASAYEGVRPELLWVESTDIERGVVDVDRVFEEADGAIVLPGFGVRGV 364
Query: 358 EGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE 417
EGKI IR RE P LGICFG QL+VVE+ARNVLG+K AH+TE++P+TP+PVVDL+PE
Sbjct: 365 EGKIEAIRRFREGKKPMLGICFGMQLSVVEYARNVLGLKEAHTTEVNPETPHPVVDLLPE 424
Query: 418 QRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVF 477
QR +DKLGGTMRLGA PV+I +GT+ + LY ++L ERHRHR+EVNP Y++ +AGLV
Sbjct: 425 QRGIDKLGGTMRLGARPVRIVEGTILWSLYGRELASERHRHRYEVNPTYVDRLVEAGLVV 484
Query: 478 SGIAGDDERRMEILEL--PDKRYFIATQFHPEFKSRPMKPAPVFHGLVKA 525
S A E +E +EL D +F+ATQFHPEFKSRP+ PAPVF G V A
Sbjct: 485 S--AWSQEGYVEAVELRPRDHPFFLATQFHPEFKSRPLNPAPVFKGFVTA 532
>gb|AAG20038.1| (AE005084) CTP synthase; PyrG [Halobacterium sp. NRC-1]
Length = 553
Score = 629 bits (1606), Expect = e-179
Identities = 312/531 (58%), Positives = 397/531 (74%), Gaps = 11/531 (2%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
+KF+FVTGGV+SGLGKGIT+AS+G L+ G+ T +KIDPY+N DAGTMNPYQHGEV+V
Sbjct: 13 SKFVFVTGGVMSGLGKGITAASLGRLLSNAGFDVTAVKIDPYLNVDAGTMNPYQHGEVYV 72
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
LDDGGEVDLDLGNYERFLD +T DHN+TTGKVY VIE+ER G+YLG TVQ+IPH+TD+
Sbjct: 73 LDDGGEVDLDLGNYERFLDEDMTSDHNVTTGKVYQDVIERERSGDYLGKTVQIIPHVTDD 132
Query: 122 IKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRV 181
IKRR+RE A D+ +VE+GGTVGDIE MPFLEA RQ E+ E++ F HVT VP +
Sbjct: 133 IKRRVREAAEGSDVCLVEVGGTVGDIEGMPFLEALRQFSHEQDDEDILFTHVTLVPYSK- 191
Query: 182 VGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVE 241
GEQKTKPTQHSVKELRS+G+QPD +V R ED L+ R+KI+LF +VP +AV S DVE
Sbjct: 192 NGEQKTKPTQHSVKELRSIGLQPDILVGRCEDRLDPDVREKIALFCDVPMDAVFSNPDVE 251
Query: 242 DTYEVPLLLEREGLGKYLVKRLGL-EDREPDLR---EWEKMVAKYKALQDSVEIAIVGKY 297
D Y VPL +E EGL +Y++++ + ED P + EW +V + + V+IA+VGKY
Sbjct: 252 DIYHVPLTVEEEGLDQYVMEQFDMVEDALPAAQRSTEWRDLVTRERT--GEVDIALVGKY 309
Query: 298 VKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGA 357
L D+Y+SI EALKHAS+ V+V + W+++E + +H + + DGI+V GGFG+RG
Sbjct: 310 A-LEDAYMSIHEALKHASLEAGVEVNVLWVDSEKMHDHHERRIADADGIVVAGGFGSRGT 368
Query: 358 EGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE 417
GKI I++ARE+D+PFLG+C GFQL VVE+ARNVLGM GAHS EID T YPV+DL+PE
Sbjct: 369 AGKIDAIQHAREHDVPFLGLCLGFQLAVVEYARNVLGMTGAHSAEIDEDTEYPVIDLLPE 428
Query: 418 QRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVF 477
Q +L+ LGGTMRLGA+ I+ GTLA++LY ERHRHR+EVNP+YI+ GL F
Sbjct: 429 QYDLEDLGGTMRLGAHETAIEPGTLAHDLYGATSCTERHRHRYEVNPEYIDDLTADGLTF 488
Query: 478 SGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
SG AG+ RMEI+E D +F TQFHPE++SRP + +P F GL+ A E
Sbjct: 489 SGEAGN---RMEIVEHDDHPFFFGTQFHPEYRSRPTRASPPFVGLLDAVLE 536
>gb|AAK40547.1| CTP synthetase (UTP-ammonia lyase) (pyrG) [Sulfolobus solfataricus]
Length = 535
Score = 629 bits (1604), Expect = e-179
Identities = 310/530 (58%), Positives = 406/530 (76%), Gaps = 9/530 (1%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+S +GKG ASIG+L+K RGY T +KIDPYIN DAGTMNPY HGEVFV
Sbjct: 4 KYIVVTGGVLSSVGKGTLVASIGMLLKRRGYNVTAVKIDPYINVDAGTMNPYMHGEVFVT 63
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
+DG E DLDLG+YERF+D ++T +NIT GKVY VI+KER G+YLG TVQ+IPH+TD+I
Sbjct: 64 EDGAETDLDLGHYERFMDVNMTKYNNITAGKVYFEVIKKEREGKYLGQTVQIIPHVTDQI 123
Query: 123 KRRIREIAR--NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
K IR ++ N +I +VEIGGTVGDIES+PFLEA RQ++LEEG +NV FVH+ V L
Sbjct: 124 KDMIRYASKINNAEITLVEIGGTVGDIESLPFLEAVRQLKLEEGEDNVIFVHIALVEYLS 183
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
V GE KTKP QHSV+ELR +GIQPD IV R+ PL++ R+KI+LFTNV + ++S+YDV
Sbjct: 184 VTGELKTKPLQHSVQELRRIGIQPDFIVGRATLPLDDETRRKIALFTNVKVDHIVSSYDV 243
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQD--SVEIAIVGKYV 298
E +YEVP++LE + L ++ RL LEDR+ DL +W V K + ++ IA+VGKY
Sbjct: 244 ETSYEVPIILESQKLVSKILSRLKLEDRQVDLTDWISFVNNIKGINSKKTINIALVGKYT 303
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE---EHGTKLLEGVDGIIVPGGFGAR 355
KL DSY+SIKEA+ HAS V+ K+ WIE+ D+E ++ ++L V+GIIV GFG+R
Sbjct: 304 KLKDSYISIKEAIYHASAYIGVRPKLIWIESTDLESDTKNLNEILGNVNGIIVLPGFGSR 363
Query: 356 GAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLM 415
GAEGKI I+YARE++IPFLGICFGFQL++VEFAR+VLG+ A+STEI+P T PV+ L+
Sbjct: 364 GAEGKIKAIKYAREHNIPFLGICFGFQLSIVEFARDVLGLSEANSTEINPNTKDPVITLL 423
Query: 416 PEQRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGL 475
EQ+N+ +LGGTMRLGA + +K+GT+AY+LY K +VYERHRHR+EVNP Y++ E AGL
Sbjct: 424 DEQKNVTQLGGTMRLGAQKIILKEGTIAYQLYGKKVVYERHRHRYEVNPKYVDILEDAGL 483
Query: 476 VFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKA 525
V SGI+ + +EI+ELP ++F+ATQ HPEFKSRP P+P++ G ++A
Sbjct: 484 VVSGIS--ENGLVEIIELPSNKFFVATQAHPEFKSRPTNPSPIYLGFIRA 531
>dbj|BAB07511.1| (AP001520) CTP synthetase [Bacillus halodurans]
Length = 532
Score = 629 bits (1604), Expect = e-179
Identities = 302/528 (57%), Positives = 396/528 (74%), Gaps = 4/528 (0%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
TK+IFVTGGVVS LGKGIT+AS+G L+K RG K T K DPYIN D GTM+PYQHGEVFV
Sbjct: 3 TKYIFVTGGVVSSLGKGITAASLGRLLKNRGMKVTIQKFDPYINVDPGTMSPYQHGEVFV 62
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
DDG E DLDLG+YERF+D +L + N+TTGK+YS+V++KERRG+YLG TVQVIPH+T+E
Sbjct: 63 TDDGAETDLDLGHYERFIDINLNKNSNVTTGKIYSSVLKKERRGDYLGGTVQVIPHVTNE 122
Query: 122 IKRRIREIAR--NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKL 179
IK R+ R N D+V+ EIGGTVGDIES+PFLEA RQ++ + G +NV ++H T +P L
Sbjct: 123 IKERVFRAGRETNADVVITEIGGTVGDIESLPFLEAIRQIKSDIGVDNVMYIHCTLIPYL 182
Query: 180 RVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYD 239
GE K+KPTQHSVKELRSLGIQP+ IV R+E P+ E ++KI+LF ++ +++VI A D
Sbjct: 183 AAAGEMKSKPTQHSVKELRSLGIQPNVIVVRTEKPVPEEMKEKIALFCDIRKDSVIEARD 242
Query: 240 VEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVK 299
+ YEVPL L+ + L + + L L +E D+ EW+ +V K K L V+IA+VGKYV
Sbjct: 243 ADTLYEVPLDLQAQNLDEIVCDHLNLSCQEADMTEWKSLVEKVKNLSGLVKIALVGKYVA 302
Query: 300 LTDSYLSIKEALKHASVSNEVKVKIRWIEAEDI-EEHGTKLLEGVDGIIVPGGFGARGAE 358
L D+YLS+ EAL+HA + + + I+W+++ED+ E+ + L+GVDGI+VPGGFG RG E
Sbjct: 303 LPDAYLSVAEALRHAGYAFDADINIKWVDSEDVTAENVAEQLQGVDGILVPGGFGDRGIE 362
Query: 359 GKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQ 418
GKI IRYARE IPFLGIC G QL +EFARNVLG++GAHS EI+P TP+P++DL+PEQ
Sbjct: 363 GKIEAIRYAREQKIPFLGICLGMQLASIEFARNVLGLEGAHSAEINPDTPHPIIDLLPEQ 422
Query: 419 RNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFS 478
++++ +GGT+RLG YP K+K GTLA Y ++YERHRHR+E N Y E E G +FS
Sbjct: 423 KDVEDMGGTLRLGLYPCKLKNGTLAQSAYNDQVIYERHRHRYEFNNQYREQMEAKGFMFS 482
Query: 479 GIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAA 526
G D R +EI+EL D +FIA+QFHPEF SRP +P P+F ++A+
Sbjct: 483 G-TSPDGRLVEIVELGDHPFFIASQFHPEFVSRPTRPQPLFREFIQAS 529
>sp|Q54775|PYRG_SYNP7 CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|1399854|gb|AAB82033.1| (U59237) CTP synthetase
[Synechococcus PCC7942]
Length = 546
Score = 621 bits (1583), Expect = e-177
Identities = 298/529 (56%), Positives = 396/529 (74%), Gaps = 4/529 (0%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
MTKFIFVTGGVVS +GKGI +AS+G L+K+RGY + +K+DPYIN D GTM+PYQHGEVF
Sbjct: 1 MTKFIFVTGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYINVDPGTMSPYQHGEVF 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DG E DLDLG+YERF DT ++ +++TTG +Y VI KERRG+Y G TVQVIPHIT
Sbjct: 61 VTADGAETDLDLGHYERFTDTPMSRLNSVTTGSIYQAVINKERRGDYNGGTVQVIPHITA 120
Query: 121 EIKRRIREIARNY--DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPK 178
EI+ RI +A++ D+V+ EIGGTVGDIES+PFLEA RQ + + GR ++A++HVT VP
Sbjct: 121 EIRDRIHRVAQDTHPDVVITEIGGTVGDIESLPFLEAIRQFRKDVGRRDLAYIHVTLVPW 180
Query: 179 LRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAY 238
+ GE KTKPTQHSVKELRS+GIQPD +V R + PL+ G ++K+S F NV EAVI++
Sbjct: 181 IPSAGEMKTKPTQHSVKELRSIGIQPDILVCRCDRPLQAGMKEKMSEFCNVSPEAVITSQ 240
Query: 239 DVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYV 298
D YEVPL+LEREGL + ++ L LE R+PDL +W++ V + + VE+ IVGKYV
Sbjct: 241 DASSIYEVPLMLEREGLAEQVLDILQLEQRQPDLTQWQRWVHQLQNPSRRVEVVIVGKYV 300
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEE-HGTKLLEGVDGIIVPGGFGARGA 357
+L D+YLS+ E+L+HA+ S + +++RW++AED+E L+GVDGI+VPGGFGARG
Sbjct: 301 RLNDAYLSVSESLRHAAASADADLQLRWVDAEDLENGDPATYLDGVDGIVVPGGFGARGV 360
Query: 358 EGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE 417
+GK+ I++AR++ IPFLG+C G Q V+++ARNV G+ GA+S E DP+TP+PV+ L+PE
Sbjct: 361 DGKVAAIQFARDHQIPFLGLCLGMQAAVIDWARNVAGLDGANSAEFDPETPHPVIALLPE 420
Query: 418 QRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVF 477
Q+++ LGGTMRLG P KI+ G+LA LY +D++YERHRHR+E N Y F ++G
Sbjct: 421 QQDVVDLGGTMRLGLCPCKIQSGSLAQRLYGEDIIYERHRHRYEFNNAYRSLFLESGYCV 480
Query: 478 SGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAA 526
SG D +EI+E PD +FIA QFHPEF SRP P P+F GL+KAA
Sbjct: 481 SG-TSPDSHLVEIVERPDHPFFIACQFHPEFVSRPNHPHPLFQGLIKAA 528
>sp|P74208|PYRG_SYNY3 CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|7438011|pir||S75840 CTP synthase (EC 6.3.4.2) -
Synechocystis sp. (strain PCC 6803)
>gi|1653385|dbj|BAA18299.1| (D90913) CTP synthetase
[Synechocystis sp.]
Length = 552
Score = 608 bits (1550), Expect = e-173
Identities = 290/528 (54%), Positives = 389/528 (72%), Gaps = 4/528 (0%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
M+KF+FVTGGVVS +GKGI +AS+G L+K+R Y + +K+DPYIN D GTM+P+QHGEVF
Sbjct: 1 MSKFVFVTGGVVSSIGKGIVAASLGRLLKSRHYSVSILKLDPYINVDPGTMSPFQHGEVF 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V +DG E DLDLG+YERF DTS++ +++TTG +Y VI KERRG Y+G TVQVIPHIT+
Sbjct: 61 VTEDGAETDLDLGHYERFTDTSMSRLNSVTTGSIYQAVINKERRGAYMGGTVQVIPHITN 120
Query: 121 EIKRRIREIARNY--DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPK 178
EIK RI +A+N D+V+ EIGGTVGDIES+PFLEA RQ + E GR NV ++HVT +P
Sbjct: 121 EIKERILRVAQNTNPDVVITEIGGTVGDIESLPFLEAIRQFRKEVGRHNVIYMHVTLIPW 180
Query: 179 LRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAY 238
+ E KTKPTQHSVKELRS+GIQPD +V R + PL G ++K+S F +VP E+VI+
Sbjct: 181 IPAAKEMKTKPTQHSVKELRSIGIQPDILVCRCDRPLHPGMKEKLSEFCDVPVESVITCQ 240
Query: 239 DVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYV 298
D YEVPL+LE+EGL ++ L +E+R PDL +W+ +V K ++ + +A+VGKYV
Sbjct: 241 DASSIYEVPLILEKEGLAHQTLELLRMENRSPDLSQWQSLVEKMQSPHHDITVALVGKYV 300
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHG-TKLLEGVDGIIVPGGFGARGA 357
+L+D+YLS+ EAL HA+++++ K+ +RWI AE+IE G L+ VDG++VPGGFG RG
Sbjct: 301 QLSDAYLSVVEALGHAAIASDSKLHLRWISAEEIEAQGAATFLKDVDGVLVPGGFGIRGV 360
Query: 358 EGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE 417
+GK+ I YAREN +PFLG+C G Q +V+E+ARNV + A+S E + +TP PV++L+PE
Sbjct: 361 DGKVQAIEYARENQLPFLGLCLGMQCSVIEWARNVAKLPEANSAEFETETPNPVINLLPE 420
Query: 418 QRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVF 477
Q+++ LGGTMRLG YP +I TLA+ LY+K++VYERHRHR+E N Y F G V
Sbjct: 421 QQDVVDLGGTMRLGLYPCRIAPDTLAFSLYQKEVVYERHRHRYEFNNSYRTQFTDTGFVV 480
Query: 478 SGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKA 525
SG D R +EI+E P +FIA QFHPEF SRP + P+F G + A
Sbjct: 481 SG-TSPDGRLVEIVEYPHHPFFIACQFHPEFHSRPNQAHPLFSGFINA 527
>emb|CAC11192.1| (AL445063) probable CTP synthase [Thermoplasma acidophilum]
Length = 540
Score = 605 bits (1542), Expect = e-172
Identities = 310/530 (58%), Positives = 387/530 (72%), Gaps = 10/530 (1%)
Query: 7 VTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVLDDGG 66
+TGGV+SGLGKG ++SIG ++K G K + +KIDPYINYDAGTMNPYQHGEVFVLDDGG
Sbjct: 1 MTGGVISGLGKGTITSSIGHILKDSGIKVSAVKIDPYINYDAGTMNPYQHGEVFVLDDGG 60
Query: 67 EVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEIKRRI 126
EVDLDLGNYERF++ +L+ D+NITTGKVY VI+KER G+YLG TVQ+IPHITDEIKRRI
Sbjct: 61 EVDLDLGNYERFMNINLSRDNNITTGKVYLEVIQKERHGDYLGKTVQIIPHITDEIKRRI 120
Query: 127 REIAR--NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRVVGE 184
RE+AR D+V++E+GGTVGDIESMPFLEA RQ++ EE +NV F HVT VP++ E
Sbjct: 121 REVARTSGADVVLIEVGGTVGDIESMPFLEALRQLKREE--QNVVFAHVTLVPEIGPTME 178
Query: 185 QKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVEDTY 244
QKTKPTQHSVK LR +GIQPD I ARS+ L E + +ISLFT+VP E +IS DVE+ Y
Sbjct: 179 QKTKPTQHSVKALREIGIQPDIIFARSKQKLTEETKSRISLFTDVPVEGIISVSDVENVY 238
Query: 245 EVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKLTDSY 304
+P ++ EGL L K L + D W + +D V++AIVGKYV L D+Y
Sbjct: 239 LLPQMMVNEGLITRLSKLLNMNIEYRD--SWTSYAENIRHPRDRVKVAIVGKYVDLHDAY 296
Query: 305 LSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGKIMTI 364
+S KEA H + + + V I WI++E ++ + L E D I++PGGFG RG EGKI
Sbjct: 297 ISHKEAFSHVTGNTGIAVDIMWIDSEKVKNDQSVLSE-ADAILIPGGFGYRGVEGKIAAT 355
Query: 365 RYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRNLDKL 424
RYA EN +PFLGIC GFQ+ V+ AR VLG+ GA+STE D +T YPVVD++PEQR + +
Sbjct: 356 RYAMENGVPFLGICLGFQVAVIAVARYVLGLDGANSTEFDEKTKYPVVDILPEQRGVKDM 415
Query: 425 GGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDD 484
GGTMRLG+ V IKKGTLA+ +Y D++YERHRHR+EVNPDYI+ EKAG FS A D+
Sbjct: 416 GGTMRLGSKKVVIKKGTLAHRIYGADVIYERHRHRYEVNPDYIDMIEKAGFKFS--ATDE 473
Query: 485 ER-RMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEK 533
E RMEILE P FIATQ+H EFKSRP+ P+ V LV+ A +K +
Sbjct: 474 EGIRMEILERPGDESFIATQYHSEFKSRPLDPSKVHLHLVEQALIFKHRR 523
>pir||B83192 CTP synthase PA3637 [imported] - Pseudomonas aeruginosa (strain
PAO1) >gi|9949796|gb|AAG07025.1|AE004783_10 (AE004783)
CTP synthase [Pseudomonas aeruginosa]
Length = 542
Score = 603 bits (1537), Expect = e-171
Identities = 296/539 (54%), Positives = 392/539 (71%), Gaps = 11/539 (2%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
MT++IFVTGGVVS LGKGI SAS+ +++ARG K T +K+DPYIN D GTM+P+QHGEVF
Sbjct: 1 MTRYIFVTGGVVSSLGKGIASASLAAILEARGLKITMLKLDPYINVDPGTMSPFQHGEVF 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DG E DLDLG+YERF+ T++T ++N TTG+VY V+ KERRG+YLGATVQVIPHITD
Sbjct: 61 VTQDGAETDLDLGHYERFVRTTMTQNNNFTTGRVYMDVLRKERRGDYLGATVQVIPHITD 120
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
EIKRRI + A + D+ +VEIGGTVGDIES PFLEA RQ+++E G + +H+T VP +
Sbjct: 121 EIKRRIIKGAGDADVALVEIGGTVGDIESQPFLEAIRQLRVEIGAKRAMLMHLTLVPYIA 180
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
GE KTKPTQHSVKELRS+G+QPD +V RS+ P++ +R+KI+LFTNV E AVI+ DV
Sbjct: 181 TAGETKTKPTQHSVKELRSIGLQPDVLVCRSDHPIDVSSRRKIALFTNVEERAVIALEDV 240
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
+ Y +P +L +GL +V+R GLE + DL EW+++V + V IA+VGKY++L
Sbjct: 241 DTIYRIPSVLHAQGLDDIVVERFGLECGQADLSEWDRVVDAKLNPEREVTIAMVGKYMEL 300
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK 360
D+Y S+ EA+ HA + + KV +R+I++EDIE+ GT LLEGVD I+VPGGFG RG EGK
Sbjct: 301 LDAYKSLIEAMTHAGIQSRTKVNLRYIDSEDIEQQGTSLLEGVDAILVPGGFGLRGVEGK 360
Query: 361 IMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE--- 417
I T++YAREN IP+LGIC G Q+ V+E+ARNVLG A+STE D + +PVV L+ E
Sbjct: 361 ISTVQYARENKIPYLGICLGMQVAVIEYARNVLGWSDANSTEFDKSSGHPVVGLITEWQD 420
Query: 418 -------QRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAF 470
+ LGGTMRLGA +++ GTL ++ Y KD++ ERHRHR+EVN + +
Sbjct: 421 ATGATEIRTEASDLGGTMRLGAQECQLQTGTLVHDCYAKDVIVERHRHRYEVNNNLLPQL 480
Query: 471 EKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEY 529
E+AGL SG +GD +E++E P+ +F+A QFHPEF S P P+F G V AA +Y
Sbjct: 481 EQAGLKISGRSGDG-ALVEVVEAPEHPWFVACQFHPEFTSTPRDGHPLFSGFVNAALKY 538
>pir||E69154 CTP synthase - Methanobacterium thermoautotrophicum (strain Delta
H) >gi|2621483|gb|AAB84925.1| (AE000826) CTP synthase
[Methanobacterium thermoautotrophicum]
Length = 533
Score = 597 bits (1523), Expect = e-170
Identities = 297/531 (55%), Positives = 389/531 (72%), Gaps = 7/531 (1%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
+ K+I VTGGVVS +GKGIT+ASIG ++++ G T IKIDPY+N+D+GT+NPYQHGEVF
Sbjct: 4 LAKYIVVTGGVVSSIGKGITAASIGRILRSYGLSVTAIKIDPYLNWDSGTLNPYQHGEVF 63
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DDG E DLDLG+YERFLD+ L + NITTGKVY +VI KER G+YLG+ VQ+IPHITD
Sbjct: 64 VTDDGMETDLDLGHYERFLDSDLPGEANITTGKVYMSVINKERSGDYLGSCVQIIPHITD 123
Query: 121 EIKRRIREIA--RNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPK 178
EIK IR+IA ++V+VE+GGTVGDIE PFLEA RQ++ EEG ENV FVHVTYVP
Sbjct: 124 EIKSMIRKIADKSGAEVVLVEVGGTVGDIEGQPFLEALRQLRNEEGHENVMFVHVTYVPY 183
Query: 179 LRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAY 238
LR GE KTKPTQHS KELRS GI PD I+ RSE P++ ++KI+ F +V EEAV++A
Sbjct: 184 LRAAGEFKTKPTQHSTKELRSTGINPDMIICRSEMPIDSSLKRKIAHFCDVEEEAVVNAP 243
Query: 239 DVEDTYEVPLLLEREGLGKYLVKRLGLE-DREPDLREWEKMVAKYKALQDSVEIAIVGKY 297
D YEVPL+L+ E +G Y+V+R+ L+ D E DL EW +V + V + IVGKY
Sbjct: 244 DASSIYEVPLVLDSERVGDYIVRRIELDVDGEADLSEWAGIVESLMIDEPVVTVGIVGKY 303
Query: 298 VKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGA 357
V+L DSY+SI+EALKHA+ V+V I WI A+D + L +D I++PGGFG RG
Sbjct: 304 VELEDSYISIREALKHAAAHLRVRVDIEWISADDAVNE--EDLSRLDSILIPGGFGERGI 361
Query: 358 EGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE 417
GK+ +R+A EN +P GIC G Q V+EFAR + GM+GA+STE DP+TPYPV+D+M E
Sbjct: 362 AGKLEAVRFALENRVPIFGICLGMQCMVIEFAR-LNGMEGANSTEFDPETPYPVIDMMEE 420
Query: 418 QRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVF 477
Q+ + +GGTMRLG+Y +I++GTLA+E Y +LV ERHRHR+E+N ++ E E GL+
Sbjct: 421 QKRIKNMGGTMRLGSYQCRIREGTLAHEAYGTELVGERHRHRFELNNEFREELESKGLII 480
Query: 478 SGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
SG + DD +E++E+ D +F+ QFHPEF+SRP + P+F ++AA E
Sbjct: 481 SGTSPDD-FLVEMVEIKDHPWFLGCQFHPEFRSRPNRAHPLFVSFLRAALE 530
>pir||F81798 CTP synthase (EC 6.3.4.2) NMA1742 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380384|emb|CAB84970.1| (AL162757) CTP synthase
[Neisseria meningitidis Z2491]
Length = 544
Score = 591 bits (1508), Expect = e-168
Identities = 288/543 (53%), Positives = 391/543 (71%), Gaps = 12/543 (2%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
MTKFIFVTGGVVS LGKGI +ASI ++++RG T +K+DPYIN D GTM+P+QHGEVF
Sbjct: 1 MTKFIFVTGGVVSSLGKGIAAASIAAILESRGLNVTMLKLDPYINVDPGTMSPFQHGEVF 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DDG E DLDLG+YERF+D+++T ++ +TG+VY VI KERRG+YLG TVQVIPHITD
Sbjct: 61 VTDDGAETDLDLGHYERFIDSTMTRRNSFSTGQVYENVIAKERRGDYLGGTVQVIPHITD 120
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
EIKRRI E A YD+ +VEIGGTVGDIES+PFLEA RQM+ + GR N F H++YVP +
Sbjct: 121 EIKRRIHEGAAGYDVAIVEIGGTVGDIESLPFLEAIRQMRSQLGRNNTLFAHLSYVPYIA 180
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
GE KTKPTQH+VKE+ S+G+QPD ++ R + + R+KI+LF NV E A++ +YDV
Sbjct: 181 AAGEIKTKPTQHTVKEMLSIGLQPDILICRMDRTMPADERRKIALFCNVEERAIVGSYDV 240
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
+ YE P +L +G+ + ++L L ++ DL W+K+V + + +V+IA+VGKYV L
Sbjct: 241 DSIYECPEMLHDQGIDNIITEQLQLNVQQADLTAWKKIVHAIQNPKHTVKIAMVGKYVDL 300
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHG--TKLLEGVDGIIVPGGFGARGAE 358
T+SY S+ EALKHA V E V+I ++++E IE++ +L+ +D I+VPGGFG+RG E
Sbjct: 301 TESYKSLIEALKHAGVHTETDVQITFVDSESIEKNNGDVSMLKDMDAILVPGGFGSRGVE 360
Query: 359 GKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQ 418
GKI +RYAREN++P+LGIC G Q+ ++E+AR+V G+KGA+STE D + PVV L+ E
Sbjct: 361 GKIAAVRYARENNVPYLGICLGMQIALIEYARDVAGLKGANSTEFDLKCAAPVVALIDEW 420
Query: 419 RNLD----------KLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIE 468
+ D LGGTMRLGA V++K G+LA ++Y + + ERHRHR+EVN +Y+
Sbjct: 421 QTADGSVETRDESADLGGTMRLGAQEVELKAGSLAAKIYGSEHIRERHRHRYEVNNNYVP 480
Query: 469 AFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
E+AGLV G++ ER +E +ELP+ +F A QFHPEF S P K P+F VKAA
Sbjct: 481 TLEQAGLVIGGVSAGRERLVETIELPNHPWFFACQFHPEFTSNPRKGHPLFTAFVKAALN 540
Query: 529 YKQ 531
K+
Sbjct: 541 NKK 543
>pir||F81070 CTP synthase NMB1554 [imported] - Neisseria meningitidis (group B
strain MD58) >gi|7226800|gb|AAF41908.1| (AE002505) CTP
synthase [Neisseria meningitidis MC58]
Length = 544
Score = 590 bits (1504), Expect = e-167
Identities = 287/543 (52%), Positives = 391/543 (71%), Gaps = 12/543 (2%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
MTKFIFVTGGVVS LGKGI +ASI ++++RG T +K+DPYIN D GTM+P+QHGEVF
Sbjct: 1 MTKFIFVTGGVVSSLGKGIAAASIAAILESRGLNVTMLKLDPYINVDPGTMSPFQHGEVF 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DDG E DLDLG+YERF+D+++T ++ +TG+VY VI KERRG+YLG TVQVIPHITD
Sbjct: 61 VTDDGAETDLDLGHYERFIDSTMTRRNSFSTGQVYENVIAKERRGDYLGGTVQVIPHITD 120
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
EIKRRI E A YD+ +VEIGGTVGDIES+PFLEA RQM+ + GR N F H++YVP +
Sbjct: 121 EIKRRIHEGAAGYDVAIVEIGGTVGDIESLPFLEAIRQMRSQLGRNNTLFAHLSYVPYIA 180
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
GE KTKPTQH+VKE+ S+G+QPD ++ R + + R+KI+LF NV E A++ +YDV
Sbjct: 181 AAGEIKTKPTQHTVKEMLSIGLQPDILICRMDRTMPADERRKIALFCNVEERAIVGSYDV 240
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
+ YE P +L +G+ + ++L L ++ DL W+K+V + + +V+IA+VGKYV L
Sbjct: 241 DSIYECPEMLHDQGIDNIITEQLQLNVQQADLTAWKKIVHAIQNPKHTVKIAMVGKYVDL 300
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEH--GTKLLEGVDGIIVPGGFGARGAE 358
T+SY S+ EALKHA + E V+I ++++E+IE++ +L+ +D I+VPGGFG+RG E
Sbjct: 301 TESYKSLIEALKHAGIHTETDVQITFVDSENIEKNKGDVSMLKDMDAILVPGGFGSRGVE 360
Query: 359 GKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQ 418
GKI +RYAREN++P+LGIC G Q+ ++E+AR+V G+KGA+STE D + PVV L+ E
Sbjct: 361 GKIAAVRYARENNVPYLGICLGMQIALIEYARDVAGLKGANSTEFDLKCAAPVVALIDEW 420
Query: 419 RNLD----------KLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIE 468
+ D LGGTMRLGA V++K G+LA ++Y + ERHRHR+EVN +Y+
Sbjct: 421 QTADGSVETRDESTDLGGTMRLGAQEVELKAGSLAAKIYGSGHIRERHRHRYEVNNNYVP 480
Query: 469 AFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
E+AGLV G++ ER +E +ELP+ +F A QFHPEF S P K P+F VKAA
Sbjct: 481 TLEQAGLVIGGVSAGRERLVETIELPNHPWFFACQFHPEFTSNPRKGHPLFTAFVKAALN 540
Query: 529 YKQ 531
K+
Sbjct: 541 NKK 543
>pir||B75379 CTP synthase - Deinococcus radiodurans (strain R1)
>gi|6459338|gb|AAF11136.1|AE002001_2 (AE002001) CTP
synthase [Deinococcus radiodurans]
Length = 544
Score = 587 bits (1497), Expect = e-166
Identities = 295/543 (54%), Positives = 376/543 (68%), Gaps = 13/543 (2%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+IFVTGGVVS LGKG+ SAS+G L++ARGYK T +KIDPYIN DAGTM PY+HGE FV
Sbjct: 2 KYIFVTGGVVSSLGKGVASASLGALLRARGYKVTAVKIDPYINIDAGTMRPYEHGECFVT 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
G E DLD+GNYERFLD + NITTG+VY VI KER G+YL TVQVIPH+TDEI
Sbjct: 62 ASGAETDLDIGNYERFLDLDIPAGSNITTGQVYQEVIRKERAGDYLSQTVQVIPHVTDEI 121
Query: 123 KRRIREIARNY--DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
KRRIR + +IV++E+GGTVGDIES+PFLEA RQ + +EG +NV ++H+T VP L
Sbjct: 122 KRRIRAAGESAGAEIVLIEVGGTVGDIESLPFLEAIRQFRFDEGDDNVLYLHLTLVPYLG 181
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
E KTKPTQHSV LRS GI PD ++ RS+D L +KI+ FT+V E V S+YDV
Sbjct: 182 TSNEFKTKPTQHSVAALRSYGISPDIVMVRSKDKLPAEITRKIAAFTSVRENRVFSSYDV 241
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
E Y+VPL LE +GLGK + + LGLE P L W V K + V IAI GKY +
Sbjct: 242 EHVYQVPLALEEQGLGKAVEELLGLEGTHPRLGVWTDAVRTIKHPKQQVTIAIAGKYTAM 301
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEG----VDGIIVPGGFGARG 356
D+YLS+ E+L HA ++N+ +V I+W+ AE + E G LEG VDGI+VPGGFG RG
Sbjct: 302 PDAYLSLMESLTHAGIANDARVNIKWVNAEQLAEAGAGELEGQFADVDGILVPGGFGIRG 361
Query: 357 AEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMP 416
EGK+ YAR + +P+LGIC G Q+ V+E+AR+V G++ A+S E D V+DLMP
Sbjct: 362 IEGKVKAAEYARTHGVPYLGICLGMQIAVIEYARHVAGIEDANSAEFDEYAKNKVIDLMP 421
Query: 417 EQRNLDKLGGTMRLGAYPVKIKKGTLAYELY---KKDLVYERHRHRWEVNPDYIEAFEKA 473
EQ + +GGTMRLG +P++++ GT ELY + V ERHRHR+EVNP Y+E E A
Sbjct: 422 EQLEVAGMGGTMRLGDWPMELRAGTKIAELYGVPQGGTVKERHRHRYEVNPAYVEQLEAA 481
Query: 474 GLVFSGIAGDDERR----MEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEY 529
GL SG+ E R +E +E+ D +F+A Q HPEFKSRPM+P+P F G VKAA E+
Sbjct: 482 GLTISGVTPGVEGRGAGLVETVEIADHPFFVALQAHPEFKSRPMRPSPPFAGFVKAALEH 541
Query: 530 KQE 532
+Q+
Sbjct: 542 QQQ 544
>pir||E82074 CTP synthase VC2448 [imported] - Vibrio cholerae (group O1 strain
N16961) >gi|9657025|gb|AAF95590.1| (AE004315) CTP
synthase [Vibrio cholerae]
Length = 545
Score = 583 bits (1486), Expect = e-165
Identities = 287/540 (53%), Positives = 385/540 (71%), Gaps = 11/540 (2%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
T +IFVTGGVVS LGKGI +AS+ +++ARG K T +K+DPYIN D GTM+P QHGEVFV
Sbjct: 3 TNYIFVTGGVVSSLGKGIAAASLAAILEARGLKVTMMKLDPYINVDPGTMSPTQHGEVFV 62
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
+DG E DLDLG+YERF+ T +T +N T G+VY+ V+ KERRG+YLGAT+QVIPHIT+
Sbjct: 63 TEDGAETDLDLGHYERFIRTKMTKRNNFTAGRVYADVLRKERRGDYLGATIQVIPHITNA 122
Query: 122 IKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRV 181
IK R+ + +DI +VE+GGTVGDIES+PF+EA RQ+ +E GRE+ F+H+T VP L
Sbjct: 123 IKDRVIAGSEGHDIAIVEVGGTVGDIESLPFMEAIRQLAIEVGREHAMFMHLTLVPYLAA 182
Query: 182 VGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVE 241
GE KTKPTQHSVKEL S+GIQPD +V RS+ + RKKI+LF NVPE+AVIS DV+
Sbjct: 183 AGEVKTKPTQHSVKELLSIGIQPDILVCRSDRMIPANERKKIALFCNVPEKAVISMKDVD 242
Query: 242 DTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKLT 301
Y++P L+ +GL + R G+ E DL EWE+++ + V I +VGKY +L
Sbjct: 243 SIYKIPQLIRSQGLDDLVCARFGINAPEADLSEWEQVIYEEANPTGEVTIGMVGKYTELP 302
Query: 302 DSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGKI 361
D+Y S+ EALKHA + N + V I++++++D+E GT +L G+D I+VPGGFG RG EGKI
Sbjct: 303 DAYKSVNEALKHAGLKNRLSVTIKYVDSQDVETKGTDVLNGLDAILVPGGFGDRGIEGKI 362
Query: 362 MTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE---- 417
+YAREN IP+LGIC G Q+ ++E+ARNV GM+GAHSTE + T YPVV L+ E
Sbjct: 363 RAAQYARENKIPYLGICLGMQVALIEYARNVAGMEGAHSTEFNKNTKYPVVGLITEWVDG 422
Query: 418 QRNLDK------LGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFE 471
+ N+++ LGGTMRLG+ ++KGT AYELY ++ERHRHR+EVN E
Sbjct: 423 EGNVEERSEKSDLGGTMRLGSQLCHLEKGTKAYELYGSATIHERHRHRYEVNNLLRPQIE 482
Query: 472 KAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQ 531
KAGL SG++ D++ +E++E P +F+A QFHPEF S P P+F G VKAA ++++
Sbjct: 483 KAGLKVSGLSA-DKKLVEVIENPAHPWFVAAQFHPEFTSTPRDGHPLFAGFVKAAGQFQR 541
>sp|P44341|PYRG_HAEIN CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|1073953|pir||F64181 CTP synthase (EC 6.3.4.2) -
Haemophilus influenzae (strain Rd KW20)
>gi|1574630|gb|AAC22733.1| (U32788) CTP synthetase
(pyrG) [Haemophilus influenzae Rd]
Length = 545
Score = 575 bits (1466), Expect = e-163
Identities = 284/537 (52%), Positives = 381/537 (70%), Gaps = 11/537 (2%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
T +IFVTGGVVS LGKGI +AS+ +++ARG T +K+DPYIN D GTM+P QHGEVFV
Sbjct: 3 TNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFV 62
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
DG E DLDLG+YERF+ T +T +N TTGK+YS V+ KERRG+YLGAT+QVIPHIT+E
Sbjct: 63 TQDGAETDLDLGHYERFIRTKMTKRNNFTTGKIYSEVLRKERRGDYLGATIQVIPHITNE 122
Query: 122 IKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRV 181
IK R+ A+ +D+V+VE+GGTVGDIES+PFLEA RQ+ ++ GRE+ F+H+T VP +
Sbjct: 123 IKDRVIAGAQGHDVVIVEVGGTVGDIESLPFLEALRQLAVQVGREHTLFMHLTLVPYIPT 182
Query: 182 VGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVE 241
GE KTKPTQHSVKEL S+GIQPD ++ RS+ + R KI+LF NV E AVIS DV
Sbjct: 183 AGEVKTKPTQHSVKELLSIGIQPDVLICRSDRMIPPNERAKIALFCNVAERAVISLKDVN 242
Query: 242 DTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKLT 301
Y++P LL+ +GL ++ +R L E DL EWE+++ K V I +VGKY +L
Sbjct: 243 SIYQIPALLKSQGLDDFVCERFRLTCPEADLTEWEQVLYKQANPVGEVTIGMVGKYTELP 302
Query: 302 DSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGKI 361
D+Y S+ EALKHA ++N + V I++I+++D+E G ++L+G+DGI+VPGGFG RG EGKI
Sbjct: 303 DAYKSVNEALKHAGLTNRLSVNIKYIDSQDVETKGVEVLKGIDGILVPGGFGYRGVEGKI 362
Query: 362 MTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRNL 421
T +YAREN IP+LGIC G Q+ ++E+ARNV G+ A+S+E D PVV L+ E ++
Sbjct: 363 RTAQYARENKIPYLGICLGMQIALIEYARNVAGLTKANSSEFDKDCEQPVVALITEWQDA 422
Query: 422 D----------KLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFE 471
+ LGGTMRLGA + G+ A ELY K+ + ERHRHR+EVN + E
Sbjct: 423 EGNTEVRTDESDLGGTMRLGAQQCHLVSGSRARELYGKETIEERHRHRYEVNNTLLPQIE 482
Query: 472 KAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
KAGL +G++ D++ +EI+E+P+ +F+A QFHPEF S P P+F G VKAA E
Sbjct: 483 KAGLKVTGLSA-DKKLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAYE 538
>dbj|BAB00835.1| (AB024033) CTP synthase [Arabidopsis thaliana]
>gi|10645538|gb|AAG21649.1|AC069474_28 (AC069474)
CTP-synthetase, putative; 3708-7443 [Arabidopsis
thaliana]
Length = 591
Score = 575 bits (1465), Expect = e-163
Identities = 299/548 (54%), Positives = 381/548 (68%), Gaps = 28/548 (5%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ VTGGVVSGLGKG+T++SIGLL++A G + T+IKIDPY+N DAGTM+P++HGEVFVL
Sbjct: 2 KYVLVTGGVVSGLGKGVTASSIGLLLQACGLRVTSIKIDPYLNTDAGTMSPFEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGEVDLDLGNYERFLD++LT D+NITTGK+Y +VI+KER+G+YLG TVQV+PH+TD I
Sbjct: 62 DDGGEVDLDLGNYERFLDSTLTRDNNITTGKIYQSVIDKERKGDYLGRTVQVVPHVTDAI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ I +A D+ V+E+GGT+GDIESMPF+EA Q + G N VHV+
Sbjct: 122 QEWIERVANVPVDGKEGPPDVCVIELGGTIGDIESMPFIEALGQFSYKVGPGNFCLVHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP L VVGEQKTKPTQHSV+ LRSLG+ P+ + RS LEE + K+S F +VPE +
Sbjct: 182 LVPVLSVVGEQKTKPTQHSVRGLRSLGLTPNILACRSTKALEENVKTKLSQFCHVPEVNI 241
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDR-EPDLREWEKMVAKYKALQDSVEIAI 293
++ YDV + + VPLLL + + +++ L L + +PDL EW Y LQD V IA+
Sbjct: 242 VTLYDVPNIWHVPLLLRDQKAHEAILRELNLSNAIKPDLTEWTARTKIYDTLQDPVRIAM 301
Query: 294 VGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTK-----------LLEG 342
VGKY LTDSYLS+ +AL HASV+ K+ I W+ A D+EE + LL+G
Sbjct: 302 VGKYTGLTDSYLSVLKALLHASVACHKKLVIEWVAASDLEEITAQETPDVHKAAWDLLKG 361
Query: 343 VDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTE 402
DGI+VPGGFG RG +GKI+ +YAREN +PFLGIC G QL VVEFAR++LG A+STE
Sbjct: 362 ADGILVPGGFGDRGVQGKILATKYARENQVPFLGICLGMQLAVVEFARSILGFHDANSTE 421
Query: 403 IDPQTPYPVVDLMPEQRNLDKLGGTMRLGA----YPVKIKKGTLAYELYKKDLVYERHRH 458
+P+T P + MPE + +GGTMRLG+ + V K Y K V ERHRH
Sbjct: 422 FEPETSSPCIIFMPE-GSTTHMGGTMRLGSRKTYFQVADCKSAKLYGNAK--FVDERHRH 478
Query: 459 RWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPV 518
R+EVNPD I EKAGL F G + RRMEI+ELP YF+ QFHPEFKSRP KP+ +
Sbjct: 479 RYEVNPDMISEIEKAGLSFVG-KDETGRRMEIVELPSHPYFVGAQFHPEFKSRPGKPSAL 537
Query: 519 FHGLVKAA 526
F GL+ AA
Sbjct: 538 FLGLIAAA 545
>gb|AAA24485.1| (M12843) CTP synthetase (EC 6.3.4.2) [Escherichia coli]
Length = 545
Score = 572 bits (1459), Expect = e-162
Identities = 283/542 (52%), Positives = 382/542 (70%), Gaps = 11/542 (2%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
T +IFVTGGVVS LGKGI +AS+ +++ARG T +K+DPYIN D GTM+P QHGEVFV
Sbjct: 3 TNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFV 62
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
+DG E DLDLG+YERF+ T ++ +N TTG++YS V+ KERRG+YLGATVQVIPHIT+
Sbjct: 63 TEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNA 122
Query: 122 IKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRV 181
IK R+ E +D+V+VEIGGTVGDIES+PFLEA RQM +E GRE+ F+H+T VP +
Sbjct: 123 IKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAA 182
Query: 182 VGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVE 241
GE KTKPTQHSVKEL S+GIQPD ++ RS+ + R KI+LF NVPE+AVIS DV+
Sbjct: 183 SGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVD 242
Query: 242 DTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKLT 301
Y++P LL+ +GL Y+ KR L E +L EWE+++ + V I +VGKY++L
Sbjct: 243 SIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELP 302
Query: 302 DSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGKI 361
D+Y S+ EALKH + N V V I+ I+++D+E G ++L+G+D I+VPGGFG RG EG I
Sbjct: 303 DAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGLEILKGLDAILVPGGFGYRGVEGMI 362
Query: 362 MTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN- 420
T R+AREN+IP+LGIC G Q+ ++++AR+V M+ A+STE P YPVV L+ E R+
Sbjct: 363 TTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDE 422
Query: 421 ---------LDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFE 471
LGGTMRLGA ++ +L +LY + ERHRHR+EVN ++ E
Sbjct: 423 NGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNSLLKQIE 482
Query: 472 KAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQ 531
AGL +G +GDD+ +EI+E+P+ +F+A QFHPEF S P P+F G VKAA E+++
Sbjct: 483 DAGLRVAGRSGDDQ-LVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQK 541
Query: 532 EK 533
+
Sbjct: 542 RQ 543
>sp|P08398|PYRG_ECOLI CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|7428507|pir||SYECTP CTP synthase (EC 6.3.4.2)
[validated] - Escherichia coli >gi|882674|gb|AAA69290.1|
(U29580) CTP synthetase [Escherichia coli]
>gi|1789142|gb|AAC75822.1| (AE000361) CTP synthetase
[Escherichia coli K12]
Length = 545
Score = 571 bits (1457), Expect = e-162
Identities = 283/542 (52%), Positives = 382/542 (70%), Gaps = 11/542 (2%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
T +IFVTGGVVS LGKGI +AS+ +++ARG T +K+DPYIN D GTM+P QHGEVFV
Sbjct: 3 TNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFV 62
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
+DG E DLDLG+YERF+ T ++ +N TTG++YS V+ KERRG+YLGATVQVIPHIT+
Sbjct: 63 TEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNA 122
Query: 122 IKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRV 181
IK R+ E +D+V+VEIGGTVGDIES+PFLEA RQM +E GRE+ F+H+T VP +
Sbjct: 123 IKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAA 182
Query: 182 VGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVE 241
GE KTKPTQHSVKEL S+GIQPD ++ RS+ + R KI+LF NVPE+AVIS DV+
Sbjct: 183 SGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVD 242
Query: 242 DTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKLT 301
Y++P LL+ +GL Y+ KR L E +L EWE+++ + V I +VGKY++L
Sbjct: 243 SIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELP 302
Query: 302 DSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGKI 361
D+Y S+ EALKH + N V V I+ I+++D+E G ++L+G+D I+VPGGFG RG EG I
Sbjct: 303 DAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMI 362
Query: 362 MTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN- 420
T R+AREN+IP+LGIC G Q+ ++++AR+V M+ A+STE P YPVV L+ E R+
Sbjct: 363 TTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDE 422
Query: 421 ---------LDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFE 471
LGGTMRLGA ++ +L +LY + ERHRHR+EVN ++ E
Sbjct: 423 NGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIE 482
Query: 472 KAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQ 531
AGL +G +GDD+ +EI+E+P+ +F+A QFHPEF S P P+F G VKAA E+++
Sbjct: 483 DAGLRVAGRSGDDQ-LVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQK 541
Query: 532 EK 533
+
Sbjct: 542 RQ 543
>emb|CAA09021.2| (AJ010153) CTP synthetase [Lactococcus lactis subsp. cremoris]
Length = 535
Score = 569 bits (1450), Expect = e-161
Identities = 276/531 (51%), Positives = 379/531 (70%), Gaps = 5/531 (0%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
TK+IFVTGG S +GKGI +AS+G L+K RG K T K DPY+N D GTM+PYQHGEVFV
Sbjct: 3 TKYIFVTGGGTSSMGKGIVAASLGRLLKNRGLKVTVQKFDPYLNIDPGTMSPYQHGEVFV 62
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
DDG E DLDLG+YERF+D +L N+T+GKVYS ++ KER+GEYLGATVQ++PH+T+
Sbjct: 63 TDDGAETDLDLGHYERFIDINLNKYSNVTSGKVYSEILRKERKGEYLGATVQMVPHVTNM 122
Query: 122 IKRRIREIAR--NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKL 179
+K +I+ A + DI++ E+GGTVGD+ES+PF+EA RQM+ E G +NV ++H + L
Sbjct: 123 LKEKIKRAATTTDADIIITEVGGTVGDMESLPFIEALRQMKAEVGADNVMYIHTVPILHL 182
Query: 180 RVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYD 239
R GE KTK Q++ K LR GIQ + +V RSE P+ R KI++F +V EAVI + D
Sbjct: 183 RAAGELKTKIAQNATKTLREYGIQANMLVLRSEVPITTEMRDKIAMFCDVAPEAVIQSLD 242
Query: 240 VEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVK 299
VE Y++PL L+ + + + + L L+ + D+ EW MV L+ V+IA+VGKYV+
Sbjct: 243 VEHLYQIPLNLQAQNMDQIVCDHLKLDAPKADMAEWSAMVDHVMNLKKKVKIALVGKYVE 302
Query: 300 LTDSYLSIKEALKHASVSNEVKVKIRWIEAEDI-EEHGTKLLEGVDGIIVPGGFGARGAE 358
L D+Y+S+ EALKHA +++ +V I W+ A D+ +E+ +L+ GIIVPGGFG RG E
Sbjct: 303 LPDAYISVTEALKHAGYASDAEVDINWVNANDVTDENVAELVGDAAGIIVPGGFGQRGTE 362
Query: 359 GKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQ 418
GKI I+YAREND+P LGIC G QLT VEFARNVLG++GAHS E+DP+T YPV+D+M +Q
Sbjct: 363 GKIAAIKYARENDVPMLGICLGMQLTAVEFARNVLGLEGAHSFELDPETKYPVIDIMRDQ 422
Query: 419 RNLDKLGGTMRLGAYPVKIKKGTLAYELYK-KDLVYERHRHRWEVNPDYIEAFEKAGLVF 477
+++ +GGT+RLG YP K+K G+ A Y ++V RHRHR+E N Y E FEKAG VF
Sbjct: 423 VDVEDMGGTLRLGLYPAKLKNGSRAKAAYNDAEVVQRRHRHRYEFNNKYREDFEKAGFVF 482
Query: 478 SGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
SG++ D R +EI+EL K++F+A Q+HPE +SRP +P ++ ++ A E
Sbjct: 483 SGVS-PDNRLVEIVELSGKKFFVACQYHPELQSRPNRPEELYTEFIRVAVE 532
>sp|P57491|PYRG_BUCAI CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|10039080|dbj|BAB13114.1| (AP001119) CTP synthase
[Buchnera sp. APS]
Length = 545
Score = 568 bits (1448), Expect = e-161
Identities = 279/543 (51%), Positives = 389/543 (71%), Gaps = 13/543 (2%)
Query: 1 MTK-FIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEV 59
MTK +IF+TGGVVS LGKGI +AS+G ++KAR T IK+DPYIN D GT++P QHGEV
Sbjct: 1 MTKNYIFITGGVVSSLGKGIAAASLGAILKARNLNITIIKLDPYINVDPGTISPIQHGEV 60
Query: 60 FVLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHIT 119
FV +DG E DLDLG+YERF+ T +TF +N TTG VYS V++KERRG+YLGAT+QVIPHIT
Sbjct: 61 FVTEDGAETDLDLGHYERFIHTKMTFLNNFTTGGVYSQVLKKERRGDYLGATIQVIPHIT 120
Query: 120 DEIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKL 179
+ IK RI + N +I++VEIGGTVGDIES+PFLEA RQM ++ GR+NV ++H+T VP +
Sbjct: 121 NAIKERIILCSENSNIILVEIGGTVGDIESLPFLEAIRQMAVDIGRKNVIYIHLTLVPYI 180
Query: 180 RVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYD 239
GE KTKPTQHSVK+L S+GIQPD ++ RSE + RKKI+LF NVP +AVIS D
Sbjct: 181 ATAGEIKTKPTQHSVKQLLSIGIQPDILICRSEKTVPLHERKKIALFCNVPVDAVISLKD 240
Query: 240 VEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVK 299
V Y++P LL+ + L Y+ L E DL+EWE+++ K +++ I I+GKY+K
Sbjct: 241 VNSIYKIPKLLKNQKLDDYICNYFKLNVPEADLQEWEEVIYAEKNFNNTIVIGIIGKYIK 300
Query: 300 LTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEG 359
L D+Y S+ EALKHA N++KV I+ I+++++E ++L+ ++GI++PGGFG RG G
Sbjct: 301 LPDAYKSVMEALKHAGFKNKIKVDIQLIDSQEVENKNFQILKNLNGILIPGGFGDRGIVG 360
Query: 360 KIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQ- 418
K+++I+YAREN IP+ GIC G Q+ ++EFA+NV+G+K A+STE DPQ YP++DL+ +
Sbjct: 361 KLLSIQYARENHIPYFGICLGMQIAIIEFAQNVVGIKEANSTEFDPQCKYPIIDLIKNRP 420
Query: 419 ----RNLDK------LGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIE 468
+N +K LGGTMRLG+ P K+ +L+ +LY ++++ ERHRHR+EVN +
Sbjct: 421 NNSSKNYNKIENRINLGGTMRLGSQPCKLSANSLSRKLYNQEIIIERHRHRYEVNNLLFK 480
Query: 469 AFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
E AGL +G +EI+EL + +F+A QFHPEF S P P+F +K+A +
Sbjct: 481 KIEAAGLQVTG-RSQKNNVVEIIELSNHPWFLACQFHPEFTSTPRDGHPLFIDFIKSAGK 539
Query: 529 YKQ 531
+K+
Sbjct: 540 HKK 542
>pir||C82700 CTP synthetase XF1288 [imported] - Xylella fastidiosa (strain
9a5c) >gi|9106277|gb|AAF84097.1|AE003962_7 (AE003962)
CTP synthetase [Xylella fastidiosa]
Length = 554
Score = 567 bits (1446), Expect = e-160
Identities = 288/544 (52%), Positives = 378/544 (68%), Gaps = 15/544 (2%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
MT IFVTGGVVS LGKGI +AS+ +++ARG K T +K+DPYIN D GTM+P+QHGEV+
Sbjct: 1 MTPLIFVTGGVVSSLGKGIAAASLASILEARGLKVTMVKLDPYINVDPGTMSPFQHGEVY 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DDG E DLDLG+YERF+ T L+ ++++TTG++Y VI KERRG+YLGATVQVIPHITD
Sbjct: 61 VTDDGAETDLDLGHYERFVRTRLSRNNSVTTGRIYQNVICKERRGDYLGATVQVIPHITD 120
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
EI+R I E ++D+ +VEIGGTVGDIES+PFLEA RQ+++E G E F+H+T VP +
Sbjct: 121 EIRRCIDEATASFDVALVEIGGTVGDIESLPFLEAIRQVRIERGAERTMFMHLTLVPYIA 180
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
GE KTKPTQHSVKELRS+GIQPD ++ RSE + + R+KI+LFTNV E AVI D+
Sbjct: 181 AAGELKTKPTQHSVKELRSIGIQPDVLLCRSEQVIPDSERRKIALFTNVSERAVIGCPDI 240
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDRE--PDLREWEKMVAKYKALQDSVEIAIVGKYV 298
+ Y +PL L R+GL + ++ + L DL EWE +V K D V IA+VGKYV
Sbjct: 241 DVLYGMPLELRRQGLDEIVIDQFKLSGTASLADLSEWEDVVDAIKHPLDEVTIAVVGKYV 300
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAE 358
D+Y S+ EALKH + KV ++W+EA+D+E L+ +DGI+VPGGFG RG E
Sbjct: 301 DYQDAYKSVGEALKHGGLRQRTKVNLKWVEAQDLEGSDMGALKDIDGILVPGGFGDRGFE 360
Query: 359 GKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQ 418
GK++ RYARE +P+ GIC+G Q VV++AR+V G++GA+STE D Q+P+PV+ L+ E
Sbjct: 361 GKVLASRYAREQRVPYFGICYGMQAAVVDYARHVAGLEGANSTENDRQSPHPVIALITEW 420
Query: 419 RNL----------DKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIE 468
R LGGTMRLG ++K GTL ELY +D+V ERHRHR+E N Y
Sbjct: 421 RTTTGEVERRDEKSDLGGTMRLGLQEQRLKAGTLVRELYGRDVVGERHRHRYEFNNRYRT 480
Query: 469 AFEKAGLVFSGIAGDDERRMEILELPDKR--YFIATQFHPEFKSRPMKPAPVFHGLVKAA 526
E AGLV + + DD +E++ELP + +F+A Q HPEF S P P+F G VKAA
Sbjct: 481 QLEDAGLVIAAKSMDD-TLVEMIELPREMHPWFLACQAHPEFLSTPRDGHPLFIGFVKAA 539
Query: 527 KEYK 530
+ K
Sbjct: 540 RARK 543
>pir||T36879 probable CTP synthetase - Streptomyces coelicolor
>gi|5738492|emb|CAB52840.1| (AL109848) putative CTP
synthetase [Streptomyces coelicolor A3(2)]
Length = 549
Score = 550 bits (1402), Expect = e-155
Identities = 283/543 (52%), Positives = 378/543 (69%), Gaps = 12/543 (2%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
TK IFVTGGV S LGKG+T++S+G+L+KARG + K+DPY+N D GTMNP+QHGEVFV
Sbjct: 8 TKHIFVTGGVASSLGKGLTASSLGMLLKARGLRVVMQKLDPYLNVDPGTMNPFQHGEVFV 67
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
+DG E DLD+G+YERFLD L N+TTG+VYSTVI KERRGEYLG TVQVIPHIT+E
Sbjct: 68 TNDGAETDLDIGHYERFLDRDLDGSANVTTGQVYSTVIAKERRGEYLGDTVQVIPHITNE 127
Query: 122 IKRRIREIARN-YDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
IK RIR +A + D+V+ E+GGTVGDIES+PFLE RQ++ E GR+NV VH++ +P +
Sbjct: 128 IKHRIRRMATDEVDVVITEVGGTVGDIESLPFLETVRQVRHEVGRDNVFVVHISLLPYIG 187
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
GE KTKPTQHSV LR++GIQPDAIV R + + ++KISL +V E AV++ D
Sbjct: 188 PSGELKTKPTQHSVAALRNIGIQPDAIVLRCDREVPTAIKRKISLMCDVDEAAVVACPDA 247
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
Y++P ++ EGL Y+V+R+ L R+ D W+ ++ + + + +A+VGKY+ L
Sbjct: 248 RSIYDIPKVIHTEGLDAYVVRRMDLPFRDVDWTTWDDLLDRVHNPEHEIVMALVGKYIDL 307
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-EHGTKL-LEGVDGIIVPGGFGARGAE 358
D+YLS+ EAL+ +N+ +VKI+W+ ++D + G ++ L VD I +PGGFG RG
Sbjct: 308 PDAYLSVTEALRAGGFANKARVKIKWVTSDDCKTPAGARVQLGDVDAICIPGGFGERGVT 367
Query: 359 GKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQ 418
GK+ I+YAREN IP LG+C G Q VVE ARN+ G+ A+STE DP T +PVV M EQ
Sbjct: 368 GKVGAIQYARENGIPLLGLCLGLQCIVVEAARNLAGVADANSTEFDPATAHPVVSTMAEQ 427
Query: 419 RNL----DKLGGTMRLGAYPVKIKKGTLAYELYK-KDLVYERHRHRWEVNPDY-IEAFEK 472
++ +GGTMRLG YP K+ +G++ E+Y K+ V ERHRHR+EVN Y E +K
Sbjct: 428 LDIVAGEGDMGGTMRLGMYPAKLAEGSIVREVYDGKEYVEERHRHRYEVNNAYRAELEKK 487
Query: 473 AGLVFSGIAGDDERRMEILELPD--KRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYK 530
AG+VFSG D + +E +E P Y +ATQ HPE +SRP +P P+F GLVKAA E K
Sbjct: 488 AGIVFSG-TSPDGKLVEYVEYPRDVHPYLVATQAHPELRSRPTRPHPLFAGLVKAAVERK 546
Query: 531 QEK 533
K
Sbjct: 547 TSK 549
>pir||T05340 CTP synthase (EC 6.3.4.2) F1C12.230 - Arabidopsis thaliana
>gi|3046696|emb|CAA18258.1| (AL022224) CTP synthase like
protein [Arabidopsis thaliana]
>gi|7268827|emb|CAB79032.1| (AL161552) CTP synthase like
protein [Arabidopsis thaliana]
Length = 553
Score = 542 bits (1381), Expect = e-153
Identities = 279/540 (51%), Positives = 369/540 (67%), Gaps = 31/540 (5%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ V+GGVVSGLGKG+T++SIGL++K+ G++ T IKIDPY+N DAGTM+P +HGEV+VL
Sbjct: 2 KYVVVSGGVVSGLGKGVTASSIGLILKSCGFRVTAIKIDPYLNIDAGTMSPIEHGEVYVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGEVDLDLGNYERF+D LT ++NITTGKVY V+EKERRG+YLG TVQV+PHITD I
Sbjct: 62 DDGGEVDLDLGNYERFMDIKLTSENNITTGKVYKHVLEKERRGDYLGKTVQVVPHITDAI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
++ I AR D+ V+E+GGT+GDIESMPF+EA Q G +N +HV+
Sbjct: 122 QKWIERAARIPVDGQSGPADVCVIELGGTIGDIESMPFIEALGQFSYRVGTDNFCLIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP L V KTKPTQHSV++LR LG+ P+ + RS PLE+ + K+S F +VP E V
Sbjct: 182 LVPVLNV----KTKPTQHSVRDLRGLGLSPNILACRSTKPLEDNVKAKLSQFCHVPMENV 237
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIV 294
++ YD + + +PLLL+ + +L+ + EP L EW M L V IA+V
Sbjct: 238 VTLYDCPNIWHIPLLLK---VSNFLIHH-SFKVSEPALEEWSLMAKMTDKLHVPVRIAVV 293
Query: 295 GKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGT-----------KLLEGV 343
GKY +L DSYLSI +AL HASV+ K+ I WI A D+E+ KLL+G
Sbjct: 294 GKYTELLDSYLSIHKALLHASVARRKKLIIDWISASDLEQGAKKENPDAYKAAWKLLKGA 353
Query: 344 DGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEI 403
DG++VPGGFG+RG EGK++ +YAREN IP+LGIC G QL V+E+AR +LG+ A+STE+
Sbjct: 354 DGVLVPGGFGSRGVEGKMLAAKYARENRIPYLGICLGMQLAVIEYARTILGLADANSTEL 413
Query: 404 DPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKI-KKGTLAYELY-KKDLVYERHRHRWE 461
DP T P V MPE + +GGTMRLG+ K + + LY K V ERHRHR+E
Sbjct: 414 DPNTKNPCVIFMPE-GSKTHMGGTMRLGSRRTYFHSKDSKSARLYGNKSFVDERHRHRYE 472
Query: 462 VNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHG 521
VNP + FE +GL F+G + +RMEI+ELP+ +++ QFHPE+KSRP KP+P+F G
Sbjct: 473 VNPAMVPRFESSGLTFTG-KDETGQRMEIIELPNHPFYVGAQFHPEYKSRPGKPSPLFLG 531
>sp|P28595|PYRG_AZOBR CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|94617|pir||S25101 CTP synthase (EC 6.3.4.2) -
Azospirillum brasilense >gi|38688|emb|CAA47656.1|
(X67216) CTP synthase [Azospirillum brasilense]
>gi|741371|prf||2007261A CTP synthetase [Azospirillum
brasilense]
Length = 544
Score = 539 bits (1373), Expect = e-152
Identities = 277/542 (51%), Positives = 363/542 (66%), Gaps = 17/542 (3%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
MT++IF+TGGVVS LGKG+ SA++G L++ARGYK K+DPY+N D GTM+PYQHGEV+
Sbjct: 1 MTRYIFITGGVVSSLGKGLASAALGALLQARGYKVRLAKLDPYLNVDPGTMSPYQHGEVY 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DDG E DLDLG+YERF + NITTG++YS VI KERRG+YLGATVQVIPH+TD
Sbjct: 61 VTDDGAETDLDLGHYERFTGVAARRGDNITTGRIYSNVIAKERRGDYLGATVQVIPHVTD 120
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
+IK I + D ++ EIGGTVGDIES PFLEA RQ E G EN F+H+T +P +
Sbjct: 121 QIKDFIGAETTDEDFILCEIGGTVGDIESTPFLEAIRQFGNEVGPENALFIHLTLLPYIP 180
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
GE KTKPTQHSVKEL +GIQ + ++ R++ P+ E RKKI+LF N+ E VI+A DV
Sbjct: 181 TAGELKTKPTQHSVKELLGMGIQANILLCRADRPIPENERKKIALFCNIRPERVIAALDV 240
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGL-EDREPDLREWEKMVAKYKALQDSVEIAIVGKYVK 299
+ Y+VP+ EG ++ GL + +PDL W +V + + Q V IA+VGKY
Sbjct: 241 DSIYQVPVSYHEEGFDTQVLAYFGLPTEGKPDLSRWTSIVERVRKPQGEVTIAVVGKYTS 300
Query: 300 LTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-EHGTKLLEGVDGIIVPGGFGARGAE 358
L DSY S+ EAL H ++N VKVK+ WI++E E E + LE V GI+VPGGFG+RG E
Sbjct: 301 LLDSYKSLAEALTHGGIANNVKVKLDWIDSEIFEDESAVQRLENVHGILVPGGFGSRGTE 360
Query: 359 GKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLM--- 415
GKI ++ARE +P+ GICFG Q+ V+E ARN+ G+ A STE+ + PVV L+
Sbjct: 361 GKIRAAQFARERKVPYFGICFGMQMAVIESARNMAGIVDAGSTELG-KPGNPVVGLLGLM 419
Query: 416 ---PEQRNLDK------LGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDY 466
+L+K +GGTMRLG YP K+ G+ E+Y + ERHRHR+EVN Y
Sbjct: 420 TEWMRGNSLEKRTEGTDVGGTMRLGTYPAKLVPGSKVAEVYGTTDITERHRHRYEVNVYY 479
Query: 467 IEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAA 526
+ EK GL+FSG++ + EI+E+PD +FI QFHPE KS+P P P+F +KAA
Sbjct: 480 KDRLEKVGLLFSGLS--PTQLPEIVEIPDHPWFIGVQFHPELKSKPFDPHPLFTSFIKAA 537
Query: 527 KE 528
E
Sbjct: 538 IE 539
>sp|P52200|PYRG_SPICI CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|413755|gb|AAA26585.1| (L22971) CTP synthetase
[Spiroplasma citri]
Length = 535
Score = 538 bits (1370), Expect = e-152
Identities = 272/538 (50%), Positives = 377/538 (69%), Gaps = 11/538 (2%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
M K+IFVTGGVVSGLGKGIT++SIG+L+KA G K DPY+N D GTM+PYQHGEVF
Sbjct: 1 MAKYIFVTGGVVSGLGKGITASSIGVLLKASGLNVFMQKFDPYLNVDPGTMSPYQHGEVF 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DG E DLDLG+YERF+D +LT + NIT+G++Y VIEKERRGEY G TVQV+PH+T+
Sbjct: 61 VTTDGAETDLDLGHYERFIDENLTKESNITSGRIYKNVIEKERRGEYDGGTVQVVPHVTN 120
Query: 121 EIKRRIREIA--RNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPK 178
EIK+++ A DI++ EIGGTVGDIES+PF+EA RQ+++E+GRENV ++HV+ VP
Sbjct: 121 EIKKKVYHAASTSKADIIITEIGGTVGDIESLPFIEAIRQVRMEQGRENVIYMHVSLVPY 180
Query: 179 LRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAY 238
+ E KTKPTQHSV+EL SLGIQPD +VAR+E L++ +KI+LF N+ + V+ A
Sbjct: 181 IAASKESKTKPTQHSVRELLSLGIQPDIVVARTEQALDDNVLEKIALFCNIEKSNVLVAT 240
Query: 239 DVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYV 298
DV + E + + K L L+ + D+ EW++ V K Q +EI +VGKY+
Sbjct: 241 DVASILWSHKMYE-QNAQIVISKLLNLKSLKTDMSEWKRFVEKINQSQQVIEIKLVGKYI 299
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDI-EEHGTKLLEGVDGIIVPGGFG---- 353
+L D+YLS+ E+L+ A N+VK+KI WI+AED+ +++ +LL+ GI+VPGGF
Sbjct: 300 ELPDAYLSVSESLRIAGYENKVKIKIDWIKAEDVNKKNDQQLLKNAKGILVPGGFDERGF 359
Query: 354 -ARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVV 412
RG EGKI+ ++AREN+IPF GICFG Q V+EFARNV ++ A+S+E+ +T ++
Sbjct: 360 EGRGFEGKILACQFARENNIPFFGICFGMQAAVIEFARNVCHIQDANSSEL-TETKNAII 418
Query: 413 DLMPEQRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEK 472
D++ + D LGGT+RLG Y TLA++LY K + RHR+EVN DY E +
Sbjct: 419 DIIRGKDKTDALGGTLRLGNYKTTFVPNTLAHKLYGKKWGFRTSRHRYEVNNDYREQLAQ 478
Query: 473 AGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYK 530
AGLVFSG+ ++ +E++E+P +++A Q+HPEF SRP KP P+F+G V+A + K
Sbjct: 479 AGLVFSGLY-VEKNLVEVIEIPKYPFYLAAQYHPEFTSRPNKPNPLFNGFVQAVIKNK 535
>pir||T01513 CTP synthase (EC 6.3.4.2) T10M13.13 - Arabidopsis thaliana
>gi|2104535|gb|AAC78703.1| (AF001308) T10M13.13
[Arabidopsis thaliana] >gi|7268596|emb|CAB80705.1|
(AL161493) CTP synthase-like protein [Arabidopsis
thaliana]
Length = 539
Score = 536 bits (1365), Expect = e-151
Identities = 274/540 (50%), Positives = 370/540 (67%), Gaps = 25/540 (4%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ VTGGVVSGLGKG+T++SIG+++KA G T+IKIDPY+N DAGTM+P++HGEVFVL
Sbjct: 2 KYVLVTGGVVSGLGKGVTASSIGVVLKACGLGVTSIKIDPYLNTDAGTMSPFEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGEVDLDLGNYERFLD +LT D+NITTGK+Y +V++KER+G+YLG TVQV+PHITD I
Sbjct: 62 DDGGEVDLDLGNYERFLDVTLTKDNNITTGKIYQSVLDKERKGDYLGKTVQVVPHITDAI 121
Query: 123 KRRIREIA--------RNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
K I ++ D+ V+E+GGTVGDIESMPF+EA RQ+ G +N +HV+
Sbjct: 122 KDWIESVSLIPVDGKEGQADVCVIELGGTVGDIESMPFIEALRQLSFSVGPDNFCLIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
+P L VVGEQKTKPTQH+V+ELR+LG+ P + RS PL E + K+S F +V +
Sbjct: 182 LIPVLGVVGEQKTKPTQHTVRELRALGLTPHFLACRSAQPLLESTKAKLSQFCHVAAANI 241
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIV 294
++ +DV + + VPLLL L+ PDL W KM + L + V+IA+V
Sbjct: 242 LNIHDVPNIWHVPLLLRCNTKFNKLIS--FSVATAPDLDSWNKMAETFDNLTNHVQIAMV 299
Query: 295 GKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGT-----------KLLEGV 343
GKY+ LTDSYLS+ +AL HA ++ +K I WI A D+E+ K+L+
Sbjct: 300 GKYIGLTDSYLSVVKALLHACIACSLKPHIEWIAASDLEDESEKSTPEAHAAAWKILKSA 359
Query: 344 DGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEI 403
+ I+VPGGFG RG G ++ +YAREN IP+LGIC G Q+ V+EFAR+VLG++ A+STE
Sbjct: 360 ECILVPGGFGDRGVSGMVLAAKYARENKIPYLGICLGMQIAVIEFARSVLGLERANSTEF 419
Query: 404 DPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKI-KKGTLAYELY-KKDLVYERHRHRWE 461
D QT PVV MPE + +G TMRLG+ + + +L +LY + V ERHRHR+E
Sbjct: 420 DAQTSDPVVIFMPE-GSRTHMGSTMRLGSRRTHLHNRDSLTSKLYGQVSYVDERHRHRYE 478
Query: 462 VNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHG 521
VNP+ +A E+AGL F G D +R+E++E D +++ QFHPEFKSRP +P+P+F G
Sbjct: 479 VNPEVAQALEEAGLRFVG-KDDTGKRVEVIEFQDHPFYVGVQFHPEFKSRPTRPSPLFLG 537
>pir||T00471 CTP synthase (EC 6.3.4.2) F19I3.12 - Arabidopsis thaliana
>gi|3033384|gb|AAC12828.1| (AC004238) putative CTP
synthase [Arabidopsis thaliana]
Length = 597
Score = 533 bits (1358), Expect = e-150
Identities = 276/549 (50%), Positives = 374/549 (67%), Gaps = 29/549 (5%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ VTGGVVSGLGKGIT++S+G+L+++ G + T IKIDPY+NYDAGT++PY+HGEVFVL
Sbjct: 2 KYVLVTGGVVSGLGKGITASSVGVLLQSCGLRVTCIKIDPYLNYDAGTISPYEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDG EVDLDLGNYERFLDT+LT D+NIT GK+ V+EKER+G+YLG TVQ++PH+TD I
Sbjct: 62 DDGSEVDLDLGNYERFLDTTLTRDNNITYGKIQRYVMEKERKGDYLGETVQIVPHVTDTI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ + +A D+ ++E+GGT+GD ES PF +A Q+ GREN +HVT
Sbjct: 122 REWVERVAMIPVDGKEGPPDVCIIELGGTIGDNESRPFADALSQLSYSVGRENFCLIHVT 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP L VVGEQKTKPTQHS+K+LR G+ P+ I RS LEE + K+S F VP + +
Sbjct: 182 LVPVLSVVGEQKTKPTQHSIKDLRGFGLTPNIIACRSTKALEENVKAKLSRFCYVPIQNI 241
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLED--REPDLREWEKMVAKYKALQDSVEIA 292
S DV + + +PLLL+ + + + K L L +EP L +W MV L V IA
Sbjct: 242 FSLCDVPNIWHIPLLLKEQKAHEAISKVLNLSGIAKEPSLEKWASMVEISDGLNVPVRIA 301
Query: 293 IVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-----------EHGTKLLE 341
IVGKY L+D+YLS+ +AL HASV+ K+++ + + D+E E KLL+
Sbjct: 302 IVGKYTDLSDAYLSVLKALLHASVAFHKKLEVDMVPSCDLEKTKKQEDSRAYEAAWKLLK 361
Query: 342 GVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHST 401
+G+++PGGFG RG EG I+ +YAREN+IPFLGIC G Q+ V+EFAR++L + A+ST
Sbjct: 362 DANGVLLPGGFGDRGVEGMILAAKYARENNIPFLGICLGMQIAVIEFARSLLCLPDANST 421
Query: 402 EIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKI-KKGTLAYELY-KKDLVYERHRHR 459
E +P+T +P + MPE ++ +GGTMRLG+ K + + LY K+ V ERHRHR
Sbjct: 422 EFEPETKHPCIIFMPE-GSITHMGGTMRLGSRRAYFHDKESKSARLYGNKEFVDERHRHR 480
Query: 460 WEVNPDYIEAFEKAGLVFSGIAGDDE--RRMEILELPDKRYFIATQFHPEFKSRPMKPAP 517
+EVNPD + + E+AGL F A DE RMEI+ELP +FI QFHPE+KSRP K +P
Sbjct: 481 YEVNPDMVASLEQAGLSF---AAKDETGERMEIVELPSHPFFIGAQFHPEYKSRPRKVSP 537
Query: 518 VFHGLVKAA 526
+F GL+ A+
Sbjct: 538 LFLGLIAAS 546
>gi|4503133 CTP synthase; Cytidine 5'-triphosphate synthetase; cytidine 5-prime
triphosphate synthetase [Homo sapiens]
>gi|131735|sp|P17812|PYRG_HUMAN CTP SYNTHASE
(UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|68630|pir||SYHUTP CTP synthase (EC 6.3.4.2) - human
>gi|30293|emb|CAA36386.1| (X52142) CTP synthetase (AA
1-591) [Homo sapiens]
Length = 591
Score = 532 bits (1355), Expect = e-150
Identities = 277/548 (50%), Positives = 375/548 (67%), Gaps = 26/548 (4%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+SG+GKGI ++S+G ++K+ G T+IKIDPYIN DAGT +PY+HGEVFVL
Sbjct: 2 KYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGEVDLDLGNYERFLD LT D+N+TTGK+Y VI KER+G+YLG TVQV+PHITD I
Sbjct: 62 DDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAI 121
Query: 123 KR--------RIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ + E + V+E+GGTVGDIESMPF+EA RQ Q + REN +HV+
Sbjct: 122 QEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP+ GEQKTKPTQ+SV+ELR LG+ PD +V R +PL+ ++KIS+F +V E V
Sbjct: 182 LVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQV 241
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLE-DREPD--LREWEKMVAKYKALQDSVEI 291
I +DV Y VPLLLE +G+ Y ++RL L +R+P L +W++M +Y L ++ I
Sbjct: 242 ICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSI 301
Query: 292 AIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-----------EHGTKLL 340
A+V KY + +DSY S+ +AL+H++++ K++I++I++ D+E + L
Sbjct: 302 ALVAKYTEFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKL 361
Query: 341 EGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHS 400
G++VPGGFG RG EGKI I +AR PFLG+C G QL VVEF+RNVLG + A+S
Sbjct: 362 CSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANS 421
Query: 401 TEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIK-KGTLAYELY-KKDLVYERHRH 458
TE DP T +PVV MPE N ++GGTMRLG + K ++ +LY D + ERHRH
Sbjct: 422 TEFDPTTSHPVVVDMPE-HNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRH 480
Query: 459 RWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPV 518
R+EVNP + + E+ GL F G + E RMEI+EL D +F+ Q+HPEF SRP+KP+P
Sbjct: 481 RFEVNPVWKKCLEEQGLKFVGQDVEGE-RMEIVELEDHPFFVGVQYHPEFLSRPIKPSPP 539
Query: 519 FHGLVKAA 526
+ GL+ A+
Sbjct: 540 YFGLLLAS 547
>gb|AAD32937.1|AC004135_12 (AC004135) T17H7.12 [Arabidopsis thaliana]
Length = 654
Score = 531 bits (1354), Expect = e-150
Identities = 295/605 (48%), Positives = 377/605 (61%), Gaps = 87/605 (14%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ VTGGVVSGLGKG+T++SIG+L+KA G + T+IKIDPY+N DAGTM+P++HGEVFVL
Sbjct: 2 KYVLVTGGVVSGLGKGVTASSIGVLLKACGLRVTSIKIDPYLNTDAGTMSPFEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGEVDLDLGNYERFLD LT D+NITTGK+Y VI KER+G+YLG TVQV+PH+TD I
Sbjct: 62 DDGGEVDLDLGNYERFLDIKLTRDNNITTGKIYQHVIAKERKGDYLGKTVQVVPHVTDAI 121
Query: 123 KRRIREIA--------RNYDIVVVEIGGTVG----------------------------D 146
+ I +A D+ V+E+GGT+G D
Sbjct: 122 QDWIERVAVIPVDGEEDPADVCVIELGGTIGIQKKTGFFFFGLLFLLLLCKQRLFVFAGD 181
Query: 147 IESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRVVGEQKTKPTQHSVKELRSLGIQPDA 206
IES PF+EA Q G N VHV+ VP L VVGEQKTKPTQHSVK LR LG+ PD
Sbjct: 182 IESAPFIEALGQFSYRVGPGNFCLVHVSLVPVLNVVGEQKTKPTQHSVKGLRGLGLTPDI 241
Query: 207 IVARSEDPLEEGARKKISLFTNVPEEAVISAYDVEDTYEVPLLLEREGLGKYLVKRLGLE 266
+ RS PLE+ ++K++ F +VP E + + YDV + + +PLLL+ + + K L L
Sbjct: 242 LACRSTKPLEDNVKEKLAQFCHVPLEYIFTLYDVPNIWRIPLLLKDQKAHLAISKVLNLA 301
Query: 267 D--REPDLREWEKMVAKYKALQD--------------------------SVEIAIVGKYV 298
EP L EW L V IA+VGKY
Sbjct: 302 SILNEPSLGEWTSRAELCDNLHVPVGLSSQLLFRNRNLYIYFLTHQIILQVRIAVVGKYT 361
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEH-----------GTKLLEGVDGII 347
L+D+YLS+ +AL HASV+ K+ + W+ A D+E+ KLL+GVDGI+
Sbjct: 362 GLSDAYLSVLKALLHASVACRKKLVVDWVPACDLEKETEKENPDAYKAAWKLLKGVDGIL 421
Query: 348 VPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQT 407
VPGGFG RG EGKI+ +YAREN IPFLGIC G Q+ V+EFAR+VL ++ A+STE +P+T
Sbjct: 422 VPGGFGDRGVEGKILAAKYARENKIPFLGICLGMQIAVIEFARSVLSLQDANSTEFNPET 481
Query: 408 PYPVVDLMPEQRNLDKLGGTMRLGA----YPVKIKKGTLAYELYKKDLVYERHRHRWEVN 463
+P + MPE + +GGTMRLG+ + VK K YE K V ERHRHR+EVN
Sbjct: 482 KHPCIIFMPE-GSKTHMGGTMRLGSRKSIFNVKDSKSAKLYE--NKSFVDERHRHRYEVN 538
Query: 464 PDYIEAFEKAGLVFSGIAGDDE--RRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHG 521
PD +E EKAGL F A DE +RMEI+ELP+ +FI QFHPEFKSRP K +P+F G
Sbjct: 539 PDMVERLEKAGLSF---AAKDETGKRMEIIELPNHPFFIGAQFHPEFKSRPGKASPLFLG 595
Query: 522 LVKAA 526
L+ A+
Sbjct: 596 LIAAS 600
>gi|9055198 CTP synthetase homolog [Mus musculus] >gi|1654186|gb|AAB17729.1|
(U49385) CTP synthetase homolog [Mus musculus]
Length = 586
Score = 529 bits (1349), Expect = e-149
Identities = 287/549 (52%), Positives = 368/549 (66%), Gaps = 28/549 (5%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+SG+GKGI ++SIG ++K+ G + T IKIDPYIN DAGT +PY+HGEVFVL
Sbjct: 2 KYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
+DGGEVDLDLGNYERFLD +L D+NITTGK+Y VI KERRG+YLG TVQV+PHITD I
Sbjct: 62 NDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ + A+ + I V+E+GGT+GDIE M F+EA RQ Q + +EN +HV+
Sbjct: 122 QEWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKKENFYNIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP+ GEQKTKPTQ+SV+ LR LG+ PD IV RS P+E ++KIS+F +V E V
Sbjct: 182 LVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQV 241
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDREPD---LREWEKMVAKYKALQDSVEI 291
I +DV Y VPLLLE +G+ KY +RLGL + L +W+ M +Y+ LQ I
Sbjct: 242 ICIHDVSSIYRVPLLLEEQGVVKYFQERLGLPINDCSSNLLFKWKAMADRYERLQKICSI 301
Query: 292 AIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-----EHGTKLLEG---- 342
A+VGKY KL D Y S+ +AL+H++++ K+ + +I++ D+E E K E
Sbjct: 302 ALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKL 361
Query: 343 --VDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHS 400
DGI+VPGGFG RG GK+ I +AR IPFLGIC G QL V+EFARN L +K A+S
Sbjct: 362 CLADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGICLGMQLAVIEFARNCLNLKDANS 421
Query: 401 TEIDPQTPYPVVDLMPEQRNLDKLGGTMRLG-AYPVKIKKGTLAYELYKKDLVY--ERHR 457
TE +P TP P+V MPE N LGGTMRLG V + ++ +LY D+ Y ERHR
Sbjct: 422 TEFEPNTPVPLVIDMPE-HNPGDLGGTMRLGLRRTVFTTENSILKKLY-GDVPYIEERHR 479
Query: 458 HRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAP 517
HR+EVNP+ I FE L F G D +RMEI+EL YFI QFHPEF SRPMKP+P
Sbjct: 480 HRYEVNPNLINQFENKDLCFVG-EDVDGKRMEIVELTSHPYFIGVQFHPEFSSRPMKPSP 538
Query: 518 VFHGLVKAA 526
+ GL+ AA
Sbjct: 539 PYLGLLLAA 547
>gi|7949029 CTP synthase [Mus musculus] >gi|2494763|sp|P70698|PYRG_MOUSE CTP
SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|1515357|gb|AAB06942.1| (U49350) CTP synthetase [Mus
musculus]
Length = 591
Score = 529 bits (1348), Expect = e-149
Identities = 274/548 (50%), Positives = 372/548 (67%), Gaps = 26/548 (4%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+SG+GKG+ ++S+G ++K+ G T+ KIDPYIN DAGT +PY+HGEVFVL
Sbjct: 2 KYILVTGGVISGIGKGVIASSVGTILKSCGLHVTSFKIDPYINIDAGTFSPYEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGEVDLDLGNYERFLD LT D+N+TTGK+Y VI KER+G+YLG TVQV+PHITD I
Sbjct: 62 DDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAI 121
Query: 123 KR--------RIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ + E + V+E+GGTVGDIESMPF+EA RQ Q + REN +HV+
Sbjct: 122 QEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP+ GEQKTKPTQ+SV+ELR LG+ PD +V R +PL+ ++KIS+F +V E V
Sbjct: 182 LVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQV 241
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGL---EDREPDLREWEKMVAKYKALQDSVEI 291
I +DV Y VPLLLE +G+ Y ++RL L L +W++M +Y L ++ I
Sbjct: 242 ICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQSRKMLMKWKEMADRYDRLLETCSI 301
Query: 292 AIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-----------EHGTKLL 340
A+VGKY K +DSY S+ +AL+H++++ K++I++I++ D+E + L
Sbjct: 302 ALVGKYPKFSDSYASVIKALEHSALAINHKLEIKYIDSTDLEPSTLQEEPVRYHEAWQKL 361
Query: 341 EGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHS 400
G++VPGGFG RG EGKI I ++R+ PFLG+C G QL VVEF+RNVLG + A+S
Sbjct: 362 CSAHGVLVPGGFGVRGTEGKIQAIAWSRKQKKPFLGVCLGIQLAVVEFSRNVLGWQDANS 421
Query: 401 TEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIK-KGTLAYELY-KKDLVYERHRH 458
TE DP+T +PVV MPE N ++GGTMRLG + K ++ +LY D + ERHRH
Sbjct: 422 TEFDPKTSHPVVIDMPE-HNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDTDYLEERHRH 480
Query: 459 RWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPV 518
R+EVNP + E+ GL F G + E RMEI+EL D +F+ Q+HPEF SRP+KP+P
Sbjct: 481 RFEVNPVLKKCLEEQGLKFVGQDVEGE-RMEIVELEDHPFFVGVQYHPEFLSRPIKPSPP 539
Query: 519 FHGLVKAA 526
+ GL+ A+
Sbjct: 540 YFGLLLAS 547
>dbj|BAB14814.1| (AK024070) unnamed protein product [Homo sapiens]
Length = 586
Score = 529 bits (1348), Expect = e-149
Identities = 282/548 (51%), Positives = 365/548 (66%), Gaps = 26/548 (4%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+SG+GKGI ++SIG ++K+ G + T IKIDPYIN DAGT +PY+HGEVFVL
Sbjct: 2 KYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
+DGGEVDLDLGNYERFLD +L D+NITTGK+Y VI KERRG+YLG TVQV+PHITD +
Sbjct: 62 NDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAV 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ + A+ I V+E+GGT+GDIE MPF+EA RQ Q + REN +HV+
Sbjct: 122 QEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP+L GEQKTKPTQ+SV+ LR LG+ PD IV RS P+E ++KIS+F +V E V
Sbjct: 182 LVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSSPIEMAVKEKISMFCHVNPEQV 241
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGL---EDREPDLREWEKMVAKYKALQDSVEI 291
I +DV TY VP+LLE + + KY +RL L + L +W M +Y+ LQ I
Sbjct: 242 ICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICSI 301
Query: 292 AIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-----EHGTKLLEG---- 342
A+VGKY KL D Y S+ +AL+H++++ K+ + +I++ D+E E K E
Sbjct: 302 ALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKL 361
Query: 343 --VDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHS 400
DGI+VPGGFG RG GK+ I +AR IPFLG+C G QL V+EFARN L +K A S
Sbjct: 362 CKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDADS 421
Query: 401 TEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIK-KGTLAYELY-KKDLVYERHRH 458
TE P P P+V MPE N LGGTMRLG K + ++ +LY + ERHRH
Sbjct: 422 TEFRPNAPVPLVIDMPE-HNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRH 480
Query: 459 RWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPV 518
R+EVNP+ I+ FE+ L F G D + RMEI+EL + YF+ QFHPEF SRPMKP+P
Sbjct: 481 RFEVNPNLIKQFEQNDLSFVGQDVDGD-RMEIIELANHPYFVGVQFHPEFSSRPMKPSPP 539
Query: 519 FHGLVKAA 526
+ GL+ AA
Sbjct: 540 YLGLLLAA 547
>gi|9789919 CTP synthase II; CTP synthetase type 2 [Homo sapiens]
>gi|9651727|gb|AAF91241.1|AF226667_1 (AF226667) CTP
synthetase isoform [Homo sapiens]
Length = 586
Score = 529 bits (1347), Expect = e-149
Identities = 282/548 (51%), Positives = 365/548 (66%), Gaps = 26/548 (4%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+SG+GKGI ++SIG ++K+ G + T IKIDPYIN DAGT +PY+HGEVFVL
Sbjct: 2 KYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
+DGGEVDLDLGNYERFLD +L D+NITTGK+Y VI KERRG+YLG TVQV+PHITD +
Sbjct: 62 NDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAV 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ + A+ I V+E+GGT+GDIE MPF+EA RQ Q + REN +HV+
Sbjct: 122 QEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP+L GEQKTKPTQ+SV+ LR LG+ PD IV RS P+E ++KIS+F +V E V
Sbjct: 182 LVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQV 241
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGL---EDREPDLREWEKMVAKYKALQDSVEI 291
I +DV TY VP+LLE + + KY +RL L + L +W M +Y+ LQ I
Sbjct: 242 ICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICSI 301
Query: 292 AIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-----EHGTKLLEG---- 342
A+VGKY KL D Y S+ +AL+H++++ K+ + +I++ D+E E K E
Sbjct: 302 ALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKL 361
Query: 343 --VDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHS 400
DGI+VPGGFG RG GK+ I +AR IPFLG+C G QL V+EFARN L +K A S
Sbjct: 362 CKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDADS 421
Query: 401 TEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIK-KGTLAYELY-KKDLVYERHRH 458
TE P P P+V MPE N LGGTMRLG K + ++ +LY + ERHRH
Sbjct: 422 TEFRPNAPVPLVIDMPE-HNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRH 480
Query: 459 RWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPV 518
R+EVNP+ I+ FE+ L F G D + RMEI+EL + YF+ QFHPEF SRPMKP+P
Sbjct: 481 RFEVNPNLIKQFEQNDLSFVGQDVDGD-RMEIIELANHPYFVGVQFHPEFSSRPMKPSPP 539
Query: 519 FHGLVKAA 526
+ GL+ AA
Sbjct: 540 YLGLLLAA 547
>gb|AAC33441.1| (AF061753) CTP synthase [Nitrosomonas europaea]
Length = 524
Score = 528 bits (1346), Expect = e-149
Identities = 265/508 (52%), Positives = 351/508 (68%), Gaps = 13/508 (2%)
Query: 41 DPYINYDAGTMNPYQHGEVFVLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIE 100
DPYIN D GTMNP+QHGEVFV DDG E DLDLG+YERF+ T +T +N TTG++Y +VI
Sbjct: 1 DPYINVDPGTMNPFQHGEVFVTDDGAETDLDLGHYERFISTKMTRQNNFTTGQIYESVIR 60
Query: 101 KERRGEYLGATVQVIPHITDEIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQ 160
KERR +YLG TVQVIPHITDEIK IR + + +VEIGGTVGDIES+PFLEA RQM
Sbjct: 61 KERRADYLGGTVQVIPHITDEIKLFIRNGVSDAQVAIVEIGGTVGDIESLPFLEAIRQMS 120
Query: 161 LEEGRENVAFVHVTYVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGAR 220
++ + F+H+T +P + GE KTKPTQHSVKELR +GIQPD ++ RS+ PL R
Sbjct: 121 VQLPHHDTCFIHLTLLPYISSAGELKTKPTQHSVKELREIGIQPDVLLCRSDRPLPLEER 180
Query: 221 KKISLFTNVPEEAVISAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVA 280
+KI+LFTNV EE+VISA DV++ Y++P LL + L + + RL + R +L W+K+V
Sbjct: 181 RKIALFTNVREESVISAIDVDNIYKIPALLHEQMLDEIVCHRLDILARPANLTVWKKLVH 240
Query: 281 KYKALQDSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLL 340
+ + V IA+VGKYV LT+SY S+ EAL HA + K+ I +I++E+IE+HGT L
Sbjct: 241 ALEHPEHEVSIALVGKYVDLTESYKSLSEALIHAGIHTRCKINIHYIDSENIEQHGTGCL 300
Query: 341 EGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHS 400
+D I+VPGGFG RG EGKIM I YAR + IP+LGIC G QL V+EF+RN L ++ AHS
Sbjct: 301 TNMDAILVPGGFGKRGVEGKIMAISYARNHRIPYLGICLGMQLAVIEFSRNRLQLENAHS 360
Query: 401 TEIDPQTPYPVVDLMPEQRN----LDK------LGGTMRLGAYPVKIKKGTLAYELYKKD 450
TE DP TPYPV+ L+ E R+ ++K LGGTMRLG +K TLA+++Y D
Sbjct: 361 TEFDPDTPYPVLGLITEWRDRCGRVEKRSAQTDLGGTMRLGGQECLLKPHTLAHKIYGAD 420
Query: 451 LVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKR--YFIATQFHPEF 508
V +RHRHR+EVN ++I E+AG+ SG++ + + E++ELP +F+A QFHPEF
Sbjct: 421 KVIDRHRHRYEVNAEFIPQLEQAGMHISGLSAEGD-LCEMIELPQSEHPWFVACQFHPEF 479
Query: 509 KSRPMKPAPVFHGLVKAAKEYKQEKDAT 536
S P P+F ++AA + + D T
Sbjct: 480 TSTPRNGHPLFKSYIQAAISFAGQSDRT 507
>dbj|BAB14607.1| (AK023549) unnamed protein product [Homo sapiens]
Length = 586
Score = 525 bits (1337), Expect = e-148
Identities = 280/548 (51%), Positives = 363/548 (66%), Gaps = 26/548 (4%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+SG+GKGI ++SIG ++K+ G + T IKIDPYIN DAGT +PY+HGEVFVL
Sbjct: 2 KYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
+DGGEVDLDLGNYERFLD +L D+NITTGK+Y VI KERRG+YLG TVQV+PHITD +
Sbjct: 62 NDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAV 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ + A+ I V+E+GGT+GDIE MPF+EA RQ Q + REN +HV+
Sbjct: 122 QEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP+L GEQKTKPTQ+SV+ LR LG+ PD IV RS P+E ++KIS+ +V E V
Sbjct: 182 LVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMLCHVNPEQV 241
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGL---EDREPDLREWEKMVAKYKALQDSVEI 291
I +DV TY VP+LLE + + KY +RL L + L +W M +Y+ LQ I
Sbjct: 242 ICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICSI 301
Query: 292 AIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-----EHGTKLLEG---- 342
A+ GKY KL D Y S+ +AL+H++++ K+ + +I++ D+E E K E
Sbjct: 302 ALAGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKL 361
Query: 343 --VDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHS 400
DGI+VPGGFG RG GK+ I +AR IPFLG+C G QL V+EFARN L +K A S
Sbjct: 362 CKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDADS 421
Query: 401 TEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIK-KGTLAYELY-KKDLVYERHRH 458
TE P P P+V MPE N LGGTMRLG K + ++ +LY + ERHRH
Sbjct: 422 TEFRPNAPVPLVIDMPE-HNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRH 480
Query: 459 RWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPV 518
R+EVNP+ I+ FE+ L F G D + RMEI+EL + YF+ QFHPEF SRPMKP+P
Sbjct: 481 RFEVNPNLIKQFEQNDLSFVGQDVDGD-RMEIIELANHPYFVGVQFHPEFSSRPMKPSPP 539
Query: 519 FHGLVKAA 526
+ GL+ AA
Sbjct: 540 YLGLLLAA 547
>sp|P96351|PYRG_MYCTU CTP SYNTHETASE (CTP SYNTHASE) (UTP--AMMONIA LIGASE)
>gi|7438001|pir||B70503 probable pyrG protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|1850588|gb|AAB48045.1| (U88301) CTP synthetase
[Mycobacterium bovis] >gi|2326742|emb|CAB10956.1|
(Z98268) pyrG [Mycobacterium tuberculosis]
Length = 586
Score = 524 bits (1334), Expect = e-147
Identities = 274/543 (50%), Positives = 362/543 (66%), Gaps = 16/543 (2%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
TK +FV+GGV S LGKG+T++S+G L+ ARG T K+DPY+N D GTMNP+QHGEVFV
Sbjct: 9 TKHLFVSGGVASSLGKGLTASSLGQLLTARGLHVTMQKLDPYLNVDPGTMNPFQHGEVFV 68
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
+DG E DLD+G+YERFLD +L N+TTG+VYSTVI KERRGEYLG TVQVIPHITDE
Sbjct: 69 TEDGAETDLDVGHYERFLDRNLPGSANVTTGQVYSTVIAKERRGEYLGDTVQVIPHITDE 128
Query: 122 IKRRIREIAR------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTY 175
IKRRI +A+ D+V+ EIGGTVGDIES PFLEAARQ++ GRE+V F+HV+
Sbjct: 129 IKRRILAMAQPDADGNRPDVVITEIGGTVGDIESQPFLEAARQVRHYLGREDVFFLHVSL 188
Query: 176 VPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVI 235
VP L GE KTKPTQHSV LRS+GI PDA++ R + + E + KI+L +V + VI
Sbjct: 189 VPYLAPSGELKTKPTQHSVAALRSIGITPDALILRCDRDVPEALKNKIALMCDVDIDGVI 248
Query: 236 SAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVG 295
S D Y++P +L RE L ++V+RL L R+ D EW+ ++ + ++V IA+VG
Sbjct: 249 STPDAPSIYDIPKVLHREELDAFVVRRLNLPFRDVDWTEWDDLLRRVHEPHETVRIALVG 308
Query: 296 KYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE--EHGTKLLEGVDGIIVPGGFG 353
KYV+L+D+YLS+ EAL+ + KV+I W+ ++ E L V G+++PGGFG
Sbjct: 309 KYVELSDAYLSVAEALRAGGFKHRAKVEICWVASDGCETTSGAAAALGDVHGVLIPGGFG 368
Query: 354 ARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVD 413
RG EGKI I YAR +P LG+C G Q V+E AR+V G+ A+S E DP TP PV+
Sbjct: 369 IRGIEGKIGAIAYARARGLPVLGLCLGLQCIVIEAARSV-GLTNANSAEFDPDTPDPVIA 427
Query: 414 LMPEQRNL----DKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEA 469
MP+Q + LGGTMRLG+YP ++ ++ + Y+ V ERHRHR+EVN Y +
Sbjct: 428 TMPDQEEIVAGEADLGGTMRLGSYPAVLEPDSVVAQAYQTTQVSERHRHRYEVNNAYRDK 487
Query: 470 FEKAGLVFSGIAGDDERRMEILELPDKR--YFIATQFHPEFKSRPMKPAPVFHGLVKAAK 527
++GL FSG D +E +E P R + + TQ HPE KSRP +P P+F V AA
Sbjct: 488 IAESGLRFSG-TSPDGHLVEFVEYPPDRHPFVVGTQAHPELKSRPTRPHPLFVAFVGAAI 546
Query: 528 EYK 530
+YK
Sbjct: 547 DYK 549
>pir||F81418 CTP synthase (EC 6.3.4.2) Cj0027 [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6967532|emb|CAB72520.1|
(AL139074) CTP synthase [Campylobacter jejuni]
Length = 543
Score = 523 bits (1333), Expect = e-147
Identities = 271/541 (50%), Positives = 366/541 (67%), Gaps = 15/541 (2%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
TK+IFVTGGV+S LGKGI +ASI L+K G K + +K DPYIN D GTM+P++HGEVFV
Sbjct: 4 TKYIFVTGGVLSSLGKGIAAASIATLLKNSGLKVSILKADPYINVDPGTMSPFEHGEVFV 63
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
DDG E DLDLG+YERFLD SL+ D+N TTG+VY +VIEKERRGEYLG T+QVIPHI E
Sbjct: 64 TDDGAETDLDLGHYERFLDESLSQDNNFTTGRVYQSVIEKERRGEYLGKTIQVIPHIVGE 123
Query: 122 IKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRV 181
IK RI++ DI++VEIGGTVGDIE +PFLEA R ++LE G+ N +H+T VP ++
Sbjct: 124 IKDRIKKAGEGKDILIVEIGGTVGDIEGLPFLEAIRALRLEVGKNNAMNIHLTLVPFIKA 183
Query: 182 VGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVE 241
GE KTKPTQHSV ELR +GI PD I+ RSE L+ + KI++ V + VI + D
Sbjct: 184 AGELKTKPTQHSVGELRRIGISPDMIICRSEKALDRDLKDKIAISCGVEKNCVIESVDAA 243
Query: 242 DTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKLT 301
Y++PL ++ + + + L L++ +P++ W+ +V + A + V+IA VGKYV L
Sbjct: 244 SIYQIPLNFLKQDILSPIAEILDLKNLKPNMENWDSLVKRVIAPSNEVKIAFVGKYVDLK 303
Query: 302 DSYLSIKEALKHASVSNEVKVKIRWIEAEDIEE-HGTKLLEGVDGIIVPGGFGARGAEGK 360
+SY S+ EA+ HA + + KV+++W+++E +E +++ + V GI+V GGFG RG EGK
Sbjct: 304 ESYKSLTEAIIHAGAALDTKVELKWVDSEKLENMESSEVFKDVSGILVAGGFGYRGVEGK 363
Query: 361 IMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE--Q 418
I I+YAREN IPFLGIC G QL +VEFARNVL +K +S+E + + PVV L+ E
Sbjct: 364 IKAIQYARENKIPFLGICLGMQLALVEFARNVLKLKDVNSSEFNEKCQNPVVYLIDEFMD 423
Query: 419 RNLDK--------LGGTMRLGAYPVKIKKGTLAYELYKK-DLVYERHRHRWEVNPDYIEA 469
N +K LGGTMRLGAY IK+ +L ++Y + V ERHRHR+E NP Y
Sbjct: 424 TNGEKQIRTAKTPLGGTMRLGAYKCDIKEKSLLAKVYNEVKSVKERHRHRYEANPKYRAD 483
Query: 470 FEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEY 529
FEK GL+ ++G+ + +E +EL +F+A QFHPEF SR PV +KAA Y
Sbjct: 484 FEKYGLI---VSGESKGLIEAVELNCHPFFLAVQFHPEFTSRLEHVNPVICSFIKAAINY 540
Query: 530 K 530
+
Sbjct: 541 E 541
>sp|Q9ZM99|PYRG_HELPJ CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|7438016|pir||C71946 ctp synthase - Helicobacter
pylori (strain J99) >gi|4154844|gb|AAD05897.1|
(AE001468) CTP SYNTHASE [Helicobacter pylori J99]
Length = 538
Score = 521 bits (1327), Expect = e-147
Identities = 265/534 (49%), Positives = 358/534 (66%), Gaps = 14/534 (2%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
KFIFVTGGV+S LGKGI+S+SI L++ Y+ + +KIDPYIN D GTM+P +HGEVFV
Sbjct: 5 KFIFVTGGVLSSLGKGISSSSIATLLQHCNYQVSILKIDPYINIDPGTMSPLEHGEVFVT 64
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DG E DLD+G+YERFL+ +LT +N TTG+++S+VIE ER+GEYLG T+Q++PH+TDEI
Sbjct: 65 SDGAETDLDIGHYERFLNRNLTRLNNFTTGQIFSSVIENERKGEYLGKTIQIVPHVTDEI 124
Query: 123 KRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRVV 182
KRRI+ A+ D ++VE+GGTVGD+E M +LEA RQ++LE G E V VHVT +P ++
Sbjct: 125 KRRIKSAAKGLDFLIVEVGGTVGDMEGMFYLEAIRQLKLELGNEKVINVHVTLIPYIQTT 184
Query: 183 GEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVED 242
E KTKPTQHSV+ELR LG+ P I+ARS PL++ +KKI+L +V +++VI A D +
Sbjct: 185 NELKTKPTQHSVQELRRLGVTPQIILARSPKPLDKELKKKIALSCDVEQDSVIVATDTKS 244
Query: 243 TYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKLTD 302
Y P+L +EG+ + +R L P + W +V K A + V+I VGKY+ L +
Sbjct: 245 IYACPILFLQEGILTPIARRFNLNKLHPKMAAWNTLVEKIIAPKHKVKIGFVGKYLSLKE 304
Query: 303 SYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGKIM 362
SY S+ EAL HA + +V I W+++E+ E LEGVD I+VPGGFG RG EGKI
Sbjct: 305 SYKSLIEALIHAGAHLDTQVNIEWLDSENFNEKTD--LEGVDAILVPGGFGERGIEGKIC 362
Query: 363 TIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE--QRN 420
I+ AR +PFLGIC G QL +VEF RNVLG+KGA+STE + + YPVV L+ + +N
Sbjct: 363 AIQRARLEKLPFLGICLGMQLAIVEFCRNVLGLKGANSTEFNQRCEYPVVYLIEDFMDQN 422
Query: 421 LDK--------LGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEK 472
K LGGTMRLG Y +I +L + YKK + ERHRHR+E+NP Y + +E
Sbjct: 423 HQKQVRTYNSPLGGTMRLGEYECEIMPNSLLEKAYKKPNIKERHRHRYEINPKYRQEWEN 482
Query: 473 AGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAA 526
GL G + +E +EL D +F+ QFHPEF SR P P+ +K+A
Sbjct: 483 KGLKVVGFGAN--HLIEAIELEDHPFFVGVQFHPEFTSRLQSPNPIILDFIKSA 534
>sp|Q59321|PYRG_CHLTR CTP SYNTHETASE (CTP SYNTHASE) (UTP--AMMONIA LIGASE)
>gi|7438006|pir||H71545 probable ctp synthetase -
Chlamydia trachomatis (serotype D, strain UW3/Cx)
>gi|3328588|gb|AAC67775.1| (AE001292) CTP Synthetase
[Chlamydia trachomatis]
Length = 539
Score = 519 bits (1323), Expect = e-146
Identities = 276/537 (51%), Positives = 367/537 (67%), Gaps = 13/537 (2%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K IF+TGGVVS LGKG+T+AS+ LL++ + K +K+DPY+N D GTMNPY+HGEV+V
Sbjct: 4 KSIFLTGGVVSSLGKGLTAASLALLLERQDLKVAMLKLDPYLNVDPGTMNPYEHGEVYVT 63
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDG E DLDLG+Y RF L+ T+G++Y+ V+ KER GE+LG+TVQVIPH+T+EI
Sbjct: 64 DDGVETDLDLGHYHRFSSVQLSKYSTATSGQIYTKVLTKERNGEFLGSTVQVIPHVTNEI 123
Query: 123 KRRIREIARNY--DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
I+ A ++ DI++VEIGGT+GDIES+PFLEA RQ + E ++ ++ +H+TYVP LR
Sbjct: 124 INVIQSCADHHKPDILIVEIGGTIGDIESLPFLEAVRQFRCEHPQDCLS-IHMTYVPYLR 182
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
E KTKPTQHSV+ LRS+GI PD I+ RSE PL ++KISLF NVPE AV +A D+
Sbjct: 183 AAKEIKTKPTQHSVQNLRSIGISPDVILCRSEAPLSTEVKRKISLFCNVPEHAVFNAIDL 242
Query: 241 E-DTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMV-AKYKALQDSVEIAIVGKYV 298
E YE+PLLL +E + +L+ +LG + DL +W+ +V A + V I +VGKY+
Sbjct: 243 ERSIYEMPLLLAKENISDFLLNKLGFSPKPLDLSDWQDLVEALCDKERQHVRIGLVGKYL 302
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWI--EAEDIEEHGTKLLEGVDGIIVPGGFGARG 356
+ D+Y S+ E+L HASV +++ I E+ED+ E L DG ++PGGFG R
Sbjct: 303 EHKDAYKSVFESLFHASVPANCSLELVPIAPESEDLLEQ----LSQCDGCLIPGGFGTRS 358
Query: 357 AEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMP 416
EGKI RY RE +IP GIC G Q VVE+ARNVL A+S EI+P+TP PVV +M
Sbjct: 359 WEGKISAARYCRERNIPCFGICLGMQALVVEYARNVLDKPLANSMEINPETPDPVVCMME 418
Query: 417 EQRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLV 476
Q ++ K GGTMRLGAYP +I G+LA YK DLV ERHRHR+EVNP YIE E+ GL
Sbjct: 419 GQDSVVK-GGTMRLGAYPCRIAPGSLASAAYKTDLVQERHRHRYEVNPSYIERLEEHGLK 477
Query: 477 FSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEK 533
+G+ E EI+E+P+ R+ + QFHPEF S+ KP P+F ++AAK Y EK
Sbjct: 478 IAGVCPLGE-LCEIVEIPNHRWMLGVQFHPEFLSKLAKPHPLFIEFIRAAKAYSLEK 533
>sp|O25116|PYRG_HELPY CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|7438010|pir||E64563 CTP synthetase - Helicobacter
pylori (strain 26695) >gi|2313438|gb|AAD07406.1|
(AE000551) CTP synthetase (pyrG) [Helicobacter pylori
26695]
Length = 538
Score = 519 bits (1322), Expect = e-146
Identities = 264/534 (49%), Positives = 357/534 (66%), Gaps = 14/534 (2%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
KFIFVTGGV+S LGKGI+S+SI L++ Y+ + +KIDPYIN D GTM+P +HGEVFV
Sbjct: 5 KFIFVTGGVLSSLGKGISSSSIATLLQHCNYQVSILKIDPYINIDPGTMSPLEHGEVFVT 64
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DG E DLD+G+YERFL+ +LT +N TTG+++S+VIE ER+GEYLG T+Q++PH+TDEI
Sbjct: 65 SDGAETDLDIGHYERFLNRNLTRLNNFTTGQIFSSVIENERKGEYLGKTIQIVPHVTDEI 124
Query: 123 KRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRVV 182
KRRI+ A+ D ++VE+GGTVGD+E M +LEA RQ++LE G E V VHVT +P ++
Sbjct: 125 KRRIKSAAKGLDFLIVEVGGTVGDMEGMFYLEAIRQLKLELGNEKVINVHVTLIPYIQTT 184
Query: 183 GEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVED 242
E KTKPTQHSV+ELR LG+ P I+ARS PL++ + KI+L +V +++VI A D +
Sbjct: 185 NELKTKPTQHSVQELRRLGVTPQIILARSPKPLDKELKNKIALSCDVEQDSVIVATDTKS 244
Query: 243 TYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKLTD 302
Y P+L +EG+ + +R L P + W +V K A + V+I VGKY+ L +
Sbjct: 245 IYACPILFLQEGILTPIARRFNLNKLHPKMAAWNTLVEKIIAPKHKVKIGFVGKYLSLKE 304
Query: 303 SYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGKIM 362
SY S+ EAL HA + +V I W+++E+ E LEGVD I+VPGGFG RG EGKI
Sbjct: 305 SYKSLIEALIHAGAHLDTQVNIEWLDSENFNEKTD--LEGVDAILVPGGFGERGIEGKIC 362
Query: 363 TIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPE--QRN 420
I+ AR +PFLGIC G QL +VEF RNVLG+KGA+STE + + YPVV L+ + +N
Sbjct: 363 AIQRARLEKLPFLGICLGMQLAIVEFCRNVLGLKGANSTEFNQRCEYPVVYLIGDFMDQN 422
Query: 421 LDK--------LGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEK 472
K LGGTMRLG Y +I +L + YKK + ERHRHR+E+NP Y + +E
Sbjct: 423 HQKQVRTYNSPLGGTMRLGEYECEIMPNSLLEKAYKKPSIKERHRHRYEINPKYRQEWEN 482
Query: 473 AGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAA 526
GL G + +E +EL D +F+ QFHPEF SR P P+ +K+A
Sbjct: 483 KGLKVVGFGSN--HLIEAIELEDHPFFVGVQFHPEFTSRLQSPNPIILDFIKSA 534
>gb|AAA80195.1| (U15192) CTP synthetase [Chlamydia trachomatis]
Length = 539
Score = 518 bits (1320), Expect = e-146
Identities = 276/537 (51%), Positives = 367/537 (67%), Gaps = 13/537 (2%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K IF+TGGVVS LGKG+T+AS+ LL++ + K +K+DPY+N D GTMNPY+HGEV+V
Sbjct: 4 KSIFLTGGVVSSLGKGLTAASLALLLERQDLKVAMLKLDPYLNVDPGTMNPYEHGEVYVT 63
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDG E DLDLG+Y RF L+ T+G++Y+ V+ KER GE+LG+TVQVIPH+T+EI
Sbjct: 64 DDGVETDLDLGHYHRFSSVQLSKYSIATSGQIYTKVLTKERNGEFLGSTVQVIPHVTNEI 123
Query: 123 KRRIREIARNY--DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
I+ A ++ DI++VEIGGT+GDIES+PFLEA RQ + E ++ ++ +H+TYVP LR
Sbjct: 124 INVIQSCADHHKPDILIVEIGGTIGDIESLPFLEAVRQFRCEHPQDCLS-IHMTYVPYLR 182
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
E KTKPTQHSV+ LRS+GI PD I+ RSE PL ++KISLF NVPE AV +A D+
Sbjct: 183 AAKEIKTKPTQHSVQNLRSIGISPDVILCRSEAPLSTEVKRKISLFCNVPEHAVFNAIDL 242
Query: 241 E-DTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMV-AKYKALQDSVEIAIVGKYV 298
E YE+PLLL +E + +L+ +LG + DL +W+ +V A + V I +VGKY+
Sbjct: 243 ERSIYEMPLLLAKENISDFLLNKLGFSPKPLDLSDWQDLVEALCDKERQHVRIGLVGKYL 302
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWI--EAEDIEEHGTKLLEGVDGIIVPGGFGARG 356
+ D+Y S+ EAL HASV +++ I E+ED+ E L DG ++PGGFG R
Sbjct: 303 EHKDAYKSVFEALFHASVPANCSLELVPIAPESEDLLEQ----LSQCDGCLIPGGFGTRS 358
Query: 357 AEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMP 416
EGKI RY RE +IP GIC G Q VVE+ARNVL A+S E++P+TP PVV +M
Sbjct: 359 WEGKISAARYCREQNIPCFGICLGMQALVVEYARNVLDKPLANSMEMNPETPDPVVCMME 418
Query: 417 EQRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLV 476
Q ++ K GGTMRLGAYP +I G+LA YK DLV ERHRHR+EVNP YIE E+ GL
Sbjct: 419 GQDSVVK-GGTMRLGAYPCRIAPGSLASAAYKTDLVQERHRHRYEVNPSYIERLEEHGLK 477
Query: 477 FSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEK 533
+G+ E EI+E+P+ R+ + QFHPEF S+ KP P+F ++AAK Y EK
Sbjct: 478 IAGVCPLGE-LCEIVEIPNHRWMLGVQFHPEFLSKLAKPHPLFIEFIRAAKAYSLEK 533
>gb|AAF49665.1| (AE003532) CG6854 gene product [alt 1] [Drosophila melanogaster]
Length = 627
Score = 515 bits (1313), Expect = e-145
Identities = 276/549 (50%), Positives = 365/549 (66%), Gaps = 28/549 (5%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+SG+GKG+ ++S G L+K+ G T+IKIDPYIN DAGT +PY+HGEV+VL
Sbjct: 2 KYILVTGGVISGVGKGVIASSFGTLLKSCGLDVTSIKIDPYINIDAGTFSPYEHGEVYVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDG EVDLDLGNYERFLD +L D+NITTGK+Y VIEKER GEYLG TVQV+PHITD I
Sbjct: 62 DDGAEVDLDLGNYERFLDVTLHRDNNITTGKIYKLVIEKERTGEYLGKTVQVVPHITDAI 121
Query: 123 KRRIREIAR-------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTY 175
+ + +A+ + +VE+GGT+GDIE MPF+EA RQ Q REN HV+
Sbjct: 122 QEWVERVAQTPVQGSSKPQVCIVELGGTIGDIEGMPFVEAFRQFQFRVKRENFCLAHVSL 181
Query: 176 VPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVI 235
VP + GE KTKPTQ SV+ELR G+ PD IV RSE P+ ++KIS F +V + VI
Sbjct: 182 VPLPKATGEPKTKPTQSSVRELRGCGLSPDLIVCRSEKPIGLEVKEKISNFCHVGPDQVI 241
Query: 236 SAYDVEDTYEVPLLLEREGLGKYLVKRLGL----EDREPDLREWEKMVAKYKALQDSVEI 291
+D+ Y VPLL+E+ G+ +YL +RL L R L++W + + + ++ V I
Sbjct: 242 CIHDLNSIYHVPLLMEQNGVIEYLNERLQLNIDMSKRTKCLQQWRDLARRTETVRREVCI 301
Query: 292 AIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEE------------HGTKL 339
A+VGKY K TDSY S+ +AL+HA+++ K+++ +IE+ +EE KL
Sbjct: 302 AVVGKYTKFTDSYASVVKALQHAALAVNRKLELVFIESCLLEEETLHSEPSKYHKEWQKL 361
Query: 340 LEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAH 399
+ GI+VPGGFG+RG EGKI ++AREN P LGIC G Q V+EFARN LG+K A+
Sbjct: 362 CDS-HGILVPGGFGSRGMEGKIRACQWARENQKPLLGICLGLQAAVIEFARNKLGLKDAN 420
Query: 400 STEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIKKG-TLAYELY-KKDLVYERHR 457
+TEIDP T +V MPE + +LGGTMRLG G ++ +LY V ERHR
Sbjct: 421 TTEIDPNTANALVIDMPE-HHTGQLGGTMRLGKRITVFSDGPSVIRQLYGNPKSVQERHR 479
Query: 458 HRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAP 517
HR+EVNP Y+ E+ G+ F G D+ RMEI+EL YF+ATQ+HPE+ SRP+KP+P
Sbjct: 480 HRYEVNPKYVHLLEEQGMRFVG-TDVDKTRMEIIELSGHPYFVATQYHPEYLSRPLKPSP 538
Query: 518 VFHGLVKAA 526
F GL+ A+
Sbjct: 539 PFLGLILAS 547
>sp|P53529|PYRG_MYCLE CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|2145823|pir||S72961 CTP synthase (EC 6.3.4.2) pyrG -
Mycobacterium leprae >gi|467152|gb|AAA50916.1| (U00021)
pyrG [Mycobacterium leprae] >gi|2065220|emb|CAB08284.1|
(Z95117) PyrG [Mycobacterium leprae]
Length = 590
Score = 514 bits (1309), Expect = e-144
Identities = 269/543 (49%), Positives = 357/543 (65%), Gaps = 16/543 (2%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
TK +FV+GGV S LGKG+T++S+G L+ ARG T K+DPY+N D GTMNP+QHGEVFV
Sbjct: 9 TKHLFVSGGVASSLGKGLTASSLGQLLTARGLHVTMQKLDPYLNVDPGTMNPFQHGEVFV 68
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
+DG E DLD+G+YERFLD L+ N+TTG+VYSTVI KERRGEYLG TVQVIPHITDE
Sbjct: 69 TEDGAETDLDVGHYERFLDRDLSGSANVTTGQVYSTVIAKERRGEYLGDTVQVIPHITDE 128
Query: 122 IKRRIREIAR------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTY 175
IK+RI +A+ D+V+ EIGGTVGDIES PFLEAARQ++ + GRENV F+HV+
Sbjct: 129 IKQRIMAMAQPDGGDNRPDVVITEIGGTVGDIESQPFLEAARQVRHDLGRENVFFLHVSL 188
Query: 176 VPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVI 235
VP L GE KTKPTQHSV LRS+GI PDA++ R + + E + KI+L +V + VI
Sbjct: 189 VPHLAPSGELKTKPTQHSVAALRSIGITPDALILRCDRDVPESLKNKIALMCDVDIDGVI 248
Query: 236 SAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVG 295
S D Y++P +L RE L ++V+RL L R+ D EW+ ++ + +V IA+VG
Sbjct: 249 STPDAPSIYDIPKVLHREELDAFVVRRLNLPFRDVDWTEWDDLLRRVHEPHGTVRIALVG 308
Query: 296 KYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE--EHGTKLLEGVDGIIVPGGFG 353
KYV +D+YLS+ EAL + KV++ W+ ++D E +L V G+++PGGFG
Sbjct: 309 KYVDFSDAYLSVSEALHAGGFKHYAKVEVVWVASDDCETATGAAAVLADVHGVLIPGGFG 368
Query: 354 ARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVD 413
RG EGKI IRYAR +P LG+C G Q V+E R+V G+ A+S E +P TP PV+
Sbjct: 369 IRGIEGKIGAIRYARARGLPVLGLCLGLQCIVIEATRSV-GLVQANSAEFEPATPDPVIS 427
Query: 414 LMPEQRNL----DKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEA 469
M +Q+ + GGTMRLGAYP ++ ++ + Y V ERHRHR+EVN Y +
Sbjct: 428 TMADQKEIVAGEADFGGTMRLGAYPAVLQPASIVAQAYGTTQVSERHRHRYEVNNAYRDW 487
Query: 470 FEKAGLVFSGIAGDDERRMEILELPDKR--YFIATQFHPEFKSRPMKPAPVFHGLVKAAK 527
++GL SG D +E +E P + + TQ HPE KSRP +P P+F V AA
Sbjct: 488 IAESGLRISG-TSPDGYLVEFVEYPANMHPFVVGTQAHPELKSRPTRPHPLFVAFVGAAI 546
Query: 528 EYK 530
+YK
Sbjct: 547 DYK 549
>pir||B56447 CTP synthetase homolog - Chlamydia trachomatis
Length = 539
Score = 513 bits (1306), Expect = e-144
Identities = 274/537 (51%), Positives = 365/537 (67%), Gaps = 13/537 (2%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K IF+TGGVVS LGKG+T+AS+ LL++ + K +K+DPY+N D GTMNPY+HGEV+V
Sbjct: 4 KSIFLTGGVVSSLGKGLTAASLALLLERQDLKVAMLKLDPYLNVDPGTMNPYEHGEVYVT 63
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDG E DLDLG+Y RF L+ T+G++Y+ V+ KER GE+LG+TVQVIPH+T+EI
Sbjct: 64 DDGVETDLDLGHYHRFSSVQLSKYSIATSGQIYTKVLTKERNGEFLGSTVQVIPHVTNEI 123
Query: 123 KRRIREIARNY--DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
I+ A ++ DI++VEIGGT+GDIES+PFLEA RQ + E ++ ++ +H+ YV LR
Sbjct: 124 INVIQSCADHHKPDILIVEIGGTIGDIESLPFLEAVRQFRCEHPQDCLS-IHMPYVTYLR 182
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
E KTKPTQHSV+ LRS+GI PD I+ RSE PL ++KISLF NVPE AV +A D+
Sbjct: 183 AAKEIKTKPTQHSVQNLRSIGISPDVILCRSEAPLSTEVKRKISLFCNVPEHAVFNAIDL 242
Query: 241 E-DTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMV-AKYKALQDSVEIAIVGKYV 298
E YE+PLLL +E + +L+ +LG + DL +W+ +V A + V I +VGKY+
Sbjct: 243 ERSIYEMPLLLAKENISDFLLNKLGFSPKPLDLSDWQDLVEALCDKERQHVRIGLVGKYL 302
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWI--EAEDIEEHGTKLLEGVDGIIVPGGFGARG 356
+ D+Y S+ EAL HASV +++ I E+ED+ E L DG ++PGGFG R
Sbjct: 303 EHKDAYKSVFEALFHASVPANCSLELVPIAPESEDLLEQ----LSQCDGCLIPGGFGTRS 358
Query: 357 AEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMP 416
EGKI RY RE +IP GIC G Q VVE+ARNVL A+S E++P+TP PVV +M
Sbjct: 359 WEGKISAARYCREQNIPCFGICLGMQALVVEYARNVLDKPLANSMEMNPETPDPVVCMME 418
Query: 417 EQRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLV 476
Q ++ K GGTMRLGAYP +I G+LA YK DLV ERHRHR+EVNP YIE E+ GL
Sbjct: 419 GQDSVVK-GGTMRLGAYPCRIAPGSLASAAYKTDLVQERHRHRYEVNPSYIERLEEHGLK 477
Query: 477 FSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEK 533
+G+ E EI+E+P+ R+ + QFHPEF S+ KP P+F ++AAK Y EK
Sbjct: 478 IAGVCPLGE-LCEIVEIPNHRWMLGVQFHPEFLSKLAKPHPLFIEFIRAAKAYSLEK 533
>sp|O51522|PYRG_BORBU CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|7438009|pir||F70171 CTP synthase (pyrG) homolog -
Lyme disease spirochete >gi|2688502|gb|AAC66946.1|
(AE001159) CTP synthase (pyrG) [Borrelia burgdorferi]
Length = 533
Score = 511 bits (1302), Expect = e-144
Identities = 259/532 (48%), Positives = 363/532 (67%), Gaps = 15/532 (2%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K + +TGGV+SG+GKG+TSASI L + ++ T IK D Y+N D GT+NP +HGEVFVL
Sbjct: 6 KILVITGGVISGIGKGVTSASIARLFRY-DFRVTPIKCDGYLNTDPGTINPVEHGEVFVL 64
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGEVD+D G+YERFL+ + NIT GK+Y ++E ER+G+YLG TVQ+IPH+TDEI
Sbjct: 65 DDGGEVDMDFGHYERFLNLNAKSSWNITMGKIYKKILENERKGKYLGRTVQLIPHVTDEI 124
Query: 123 KRRIREIA--RNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
K I +IA N D++++EIGGTVGD+E++ F+E RQ++ E G N++F+H+TYVP
Sbjct: 125 KSTIFQIASSENSDMLIIEIGGTVGDMENILFIETVRQIRQEIGSGNISFIHLTYVPSPA 184
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
+ EQK+KPTQ SVK L GI PD I+ARS L + RKK+++F NV ++I DV
Sbjct: 185 GINEQKSKPTQQSVKTLNKAGIFPDLIIARSSQVLTDQIRKKVAMFCNVESTSIIDNVDV 244
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKA----LQDSVEIAIVGK 296
YE+P+ ++G+ + L +L ++ +P + E K+V K+ + + IAI GK
Sbjct: 245 STIYEIPISFYKQGVHEILSSKLNIK-VDPKIEELSKLVGVIKSNFFVPKKIINIAICGK 303
Query: 297 YVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARG 356
Y +L DSY SI+E+L H + ++ +K I++ D+ E L+ DGIIVPGGFG +G
Sbjct: 304 YAELDDSYASIRESLVHVAAHLDLLIKSTLIDSNDLNE---SCLKEFDGIIVPGGFGGKG 360
Query: 357 AEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTE---IDPQTPYPVVD 413
EGKIM I+YAREN+IPFLGIC G QL V+EFARNV G+ A + E D PV+
Sbjct: 361 YEGKIMAIKYARENNIPFLGICLGLQLAVIEFARNVCGILDADTEENLARDKPLKSPVIH 420
Query: 414 LMPEQRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKA 473
L+PEQ+ + G TMRLG YPV +KK T+A++LY +D + ER RHR+EVN DYI+ F K
Sbjct: 421 LLPEQKGIKDKGATMRLGGYPVILKKNTIAFKLYGQDRIIERFRHRYEVNNDYIDLFAKN 480
Query: 474 GLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKA 525
GL+ SG + D + +++E+P+ ++F+A QFHPE +R PA +F GL+KA
Sbjct: 481 GLIVSGFS-SDFKMAKLIEIPENKFFVACQFHPELITRIENPAKLFLGLIKA 531
>pir||D81700 CTP synthase TC0455 [imported] - Chlamydia muridarum (strain Nigg)
>gi|7190500|gb|AAF39308.1| (AE002314) CTP synthase
[Chlamydia muridarum]
Length = 536
Score = 510 bits (1298), Expect = e-143
Identities = 265/535 (49%), Positives = 360/535 (66%), Gaps = 9/535 (1%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K IF+TGGVVS LGKG+T+AS+ LL++ +G K +K+DPY+N D GTMNPY+HGEV+V
Sbjct: 4 KSIFLTGGVVSSLGKGLTAASLALLLERQGLKVAMLKLDPYLNVDPGTMNPYEHGEVYVT 63
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDG E DLDLG+Y RF L+ T+G++Y+ VI KER GE+LG+TVQVIPH+T+EI
Sbjct: 64 DDGVETDLDLGHYHRFSSVQLSKHSTATSGQIYTRVITKERNGEFLGSTVQVIPHVTNEI 123
Query: 123 KRRIREIARNY--DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
I+ A ++ D++++EIGGT+GDIES+PFLEA RQ + E ++ ++ +H+TYVP L+
Sbjct: 124 INVIQACAEHHKPDVLIIEIGGTIGDIESLPFLEAVRQFRCEHPQDCLS-IHMTYVPYLK 182
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
E KTKPTQHSV+ LRS+GI PD I+ RSE L ++KISLF NVPE AV +A D+
Sbjct: 183 SAKEIKTKPTQHSVQNLRSIGISPDVILCRSEVSLSSEVKRKISLFCNVPENAVFNAIDL 242
Query: 241 EDT-YEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKY-KALQDSVEIAIVGKYV 298
E++ YE+PLLL RE + +L+ + G + DL +W+ +V + V I +VGKY+
Sbjct: 243 ENSIYEMPLLLARENIVDFLLSKFGFSPKSLDLTDWQNLVTTLCDGNRHLVRIGLVGKYL 302
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAE 358
+ D+Y S+ E+L HAS+ ++I I E E T L DG ++PGGFG R E
Sbjct: 303 EHKDAYKSVFESLSHASIPANCSLEIVPISPE--SEALTNQLSQCDGCLIPGGFGTRSWE 360
Query: 359 GKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQ 418
GKI RY R+N+IP GIC G Q VVE+AR L + A+S E+DP TP PVV +M Q
Sbjct: 361 GKIAAARYCRDNNIPCFGICLGMQALVVEYARYALSLPLANSLEMDPNTPDPVVCMMQGQ 420
Query: 419 RNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFS 478
+ K GGTMRLGAYP +I +LA+E YK DLV ERHRHR+EVNP Y++ +K GL
Sbjct: 421 DTMIK-GGTMRLGAYPCQITPKSLAFEAYKTDLVQERHRHRYEVNPAYVDLLQKNGLRIV 479
Query: 479 GIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEK 533
G+ + EI+E+P+ R+ + QFHPEF S+ P P+F + AA +Y EK
Sbjct: 480 GVCPQGD-LCEIIEIPNHRWMLGVQFHPEFLSKLAAPHPLFVKFLSAALDYSLEK 533
>pir||T37497 probable CTP synthase - fission yeast (Schizosaccharomyces pombe)
>gi|2661608|emb|CAA15716.1| (AL009197) probable CTP
synthase [Schizosaccharomyces pombe]
Length = 600
Score = 508 bits (1293), Expect = e-143
Identities = 273/559 (48%), Positives = 367/559 (64%), Gaps = 42/559 (7%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ V+GGV+SG+GKG+ ++S GLL+K G K T+IKIDPY+N DAGTM+P +HGEVFVL
Sbjct: 2 KYVLVSGGVISGIGKGVIASSTGLLLKTLGLKVTSIKIDPYMNIDAGTMSPLEHGEVFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
+DGGEVDLDLGNYER+L+ +LT D+NITTGKVYS VI+KERRG+YLG TVQ++PH+T+EI
Sbjct: 62 NDGGEVDLDLGNYERYLNVTLTHDNNITTGKVYSNVIQKERRGDYLGKTVQIVPHVTNEI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ + +AR D+ +VE+GGTVGDIES F+EA RQ Q G EN +HV+
Sbjct: 122 QDWVERVARIPVDQSGEEPDVCIVELGGTVGDIESAAFVEAMRQFQFRVGHENFVSIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP + GEQKTKPTQ ++++LRSLGI PD I R + PLE+ KISLF +V E V
Sbjct: 182 LVPVIN--GEQKTKPTQQAIRDLRSLGITPDLIACRCKQPLEKSVIDKISLFCHVGPEQV 239
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLE----DREPDL------REWEKMVAKYKA 284
++ +DV TY VP LLE + L +YL R L+ RE L W+ + Y
Sbjct: 240 LAVHDVSSTYHVPQLLE-DKLLEYLKIRFALDKISVSRELALAGENMWSSWKHLTQGYDH 298
Query: 285 LQDSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE----------- 333
L V I +VGKY L DSY+S+ +AL+H+++ K+ ++W+EA +E
Sbjct: 299 LFKKVTIVLVGKYTHLQDSYISVIKALEHSAMRCGRKLDLQWVEASHLEASTNTSDPLSY 358
Query: 334 EHGTKLLEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVL 393
L+ +GI+VPGGFG+RG EG I ++AREN+ P+LGIC G Q+ V+EFAR+V
Sbjct: 359 HKAWHLVCSANGILVPGGFGSRGVEGMIAAAKWARENNTPYLGICLGMQVAVIEFARSVC 418
Query: 394 GMKGAHSTEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIKKGTLAYELYK----K 449
G++GA S E D + VV MPE + DKLGGTMRLG P + + +L K
Sbjct: 419 GIEGAFSEEFDKECENNVVVYMPE-IDKDKLGGTMRLGLRPTFFQPNSEWSKLRKLHKMV 477
Query: 450 DLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDER--RMEILELPDKRYFIATQFHPE 507
D V ERHRHR+E+NP ++ E+ G+ F G DER RMEI+E D YF+ Q+HPE
Sbjct: 478 DEVLERHRHRYEINPAFVSRLEQGGISF---IGKDERGERMEIIEKRDHPYFVGVQYHPE 534
Query: 508 FKSRPMKPAPVFHGLVKAA 526
+ S+P+KP+P GLV A+
Sbjct: 535 YLSKPLKPSPPIFGLVAAS 553
>gi|6319432 CTP synthase, highly homologus to URA8 CTP synthase; Ura7p
[Saccharomyces cerevisiae]
>gi|585767|sp|P28274|PYRG_YEAST CTP SYNTHASE 1
(UTP--AMMONIA LIGASE 1) (CTP SYNTHETASE 1)
>gi|1363646|pir||S50291 CTP synthase (EC 6.3.4.2) URA7 -
yeast (Saccharomyces cerevisiae)
>gi|463269|emb|CAA55055.1| (X78214) URA7 [Saccharomyces
cerevisiae] >gi|536053|emb|CAA84859.1| (Z35800) ORF
YBL039c [Saccharomyces cerevisiae]
Length = 579
Score = 503 bits (1282), Expect = e-141
Identities = 266/567 (46%), Positives = 372/567 (64%), Gaps = 43/567 (7%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ V+GGV+SG+GKG+ ++S G+LMK G K T+IKIDPY+N DAGTM+P +HGE FVL
Sbjct: 2 KYVVVSGGVISGIGKGVLASSTGMLMKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGE DLDLGNYER+L +LT DHNITTGK+YS VI KER+G+YLG TVQ++PH+T+ I
Sbjct: 62 DDGGETDLDLGNYERYLGVTLTKDHNITTGKIYSHVIAKERKGDYLGKTVQIVPHLTNAI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ I +A+ D+ ++E+GGTVGDIES PF+EA RQ Q + G+EN A +HV+
Sbjct: 122 QDWIERVAKIPVDDTGMEPDVCIIELGGTVGDIESAPFVEALRQFQFKVGKENFALIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP + GEQKTKPTQ ++K LRSLG+ PD I R + L++ KI++F +V E V
Sbjct: 182 LVPVIH--GEQKTKPTQAAIKGLRSLGLVPDMIACRCSETLDKPTIDKIAMFCHVGPEQV 239
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLED---REPDLREWEKMVAKYKAL------ 285
++ +DV TY VPLLL + + YL RL L++ E + + ++++K+KA
Sbjct: 240 VNVHDVNSTYHVPLLLLEQKMIDYLHARLKLDEISLTEEEKQRGLELLSKWKATTGNFDE 299
Query: 286 -QDSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTK------ 338
++V+IA+VGKY L DSYLS+ +AL+H+S+ K+ I+W+EA D+E +
Sbjct: 300 SMETVKIALVGKYTNLKDSYLSVIKALEHSSMKCRRKLDIKWVEATDLEPEAQESNKTKF 359
Query: 339 -----LLEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVL 393
++ DGI++PGGFG RG EG ++ R+AREN IPFLG+C G Q+ +EF R+VL
Sbjct: 360 HEAWNMVSTADGILIPGGFGVRGTEGMVLAARWARENHIPFLGVCLGLQIATIEFTRSVL 419
Query: 394 GMKGAHSTEIDPQTPYP--VVDLMPEQRNLDK--LGGTMRLGAYPVKIKKGTLAYELYK- 448
G K +HS E P VV MPE +DK +GG+MRLG P + T ++ K
Sbjct: 420 GRKDSHSAEFYPDIDEKNHVVVFMPE---IDKETMGGSMRLGLRPTFFQNETEWSQIKKL 476
Query: 449 ---KDLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFH 505
V+ERHRHR+E+NP ++ E GL+F G D +R EILEL + Y+IATQ+H
Sbjct: 477 YGDVSEVHERHRHRYEINPKMVDELENNGLIFVG-KDDTGKRCEILELKNHPYYIATQYH 535
Query: 506 PEFKSRPMKPAPVFHGLVKAAKEYKQE 532
PE+ S+ + P+ F GLV A+ Q+
Sbjct: 536 PEYTSKVLDPSKPFLGLVAASAGILQD 562
>pir||D72330 CTP synthetase - Thermotoga maritima (strain MSB8)
>gi|4981333|gb|AAD35885.1|AE001748_1 (AE001748) CTP
synthetase [Thermotoga maritima]
Length = 524
Score = 503 bits (1281), Expect = e-141
Identities = 268/522 (51%), Positives = 348/522 (66%), Gaps = 12/522 (2%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
M K++ VTGGV+SG+GKGI SAS+ LMK G +KIDPY+N DAGTMNP QHGEVF
Sbjct: 1 MKKYVIVTGGVLSGIGKGIFSASLARLMKEHGVDVNVLKIDPYLNVDAGTMNPNQHGEVF 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V +DG E DLDLG+YERFL +T +N+T G+VY VIEKER+G+YLG TVQ++PH+T+
Sbjct: 61 VTEDGYEADLDLGHYERFLGRDMTRQNNMTAGQVYLRVIEKERQGKYLGNTVQIVPHLTE 120
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
EIK RIR A +++VVEIGGTVGDIE FLEA R++Q+EEG+EN F HVTYVP LR
Sbjct: 121 EIKDRIR--ALEAELLVVEIGGTVGDIEGEVFLEAVRELQMEEGKENFLFAHVTYVPYLR 178
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
E KTKPTQ SV+ LR +GI PD ++ RSE PL+ + K++LF+ VP + VI+ D
Sbjct: 179 TTNEFKTKPTQQSVQLLRRIGITPDMVIVRSEFPLDVPSMNKVALFSGVPRDFVINLPDT 238
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
++ YEVP +L GL + + +L +E ++ W Y IA+VGKY+
Sbjct: 239 KNVYEVPEILRDMGLHEKIASKLNVELKKSTF-NW-----SYPKAFKPYRIALVGKYLGT 292
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGK 360
D+Y SI E++ + V + +E + +E K+L+ D +I+PGGFG RG EGK
Sbjct: 293 DDAYKSIIESVFLTGIEKPTVVDSQMLEDMN-DEEVKKVLDEYDALIIPGGFGRRGVEGK 351
Query: 361 IMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRN 420
I I+YAREN P LGIC G QL V+EFARNV G K A+STE DP TPYPVVDLM EQ+
Sbjct: 352 IKAIKYARENKKPILGICLGMQLMVIEFARNVFGYKEANSTEFDPNTPYPVVDLMEEQKR 411
Query: 421 LDKLGGTMRLGAYPVKIKKGTLAYELY-KKDLVYERHRHRWEVNPD-YIEAFEKAGLV-F 477
+ KLGGTMRLGA VKI T YE+Y + VYERHRHR+E N + + E F+K G +
Sbjct: 412 ILKLGGTMRLGAQKVKIFPKTKLYEVYGGVEEVYERHRHRYEANEEAFPELFKKPGEEGY 471
Query: 478 SGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVF 519
+ +E +EL D +F+ QFHPE+KS+ P P+F
Sbjct: 472 KLVVSAKSDFIEAVELEDHPFFVGVQFHPEYKSKVGAPHPIF 513
>emb|CAA37941.1| (X53995) CTP synthetase [Saccharomyces cerevisiae]
Length = 579
Score = 499 bits (1271), Expect = e-140
Identities = 264/567 (46%), Positives = 370/567 (64%), Gaps = 43/567 (7%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ V+GGV+SG+GKG+ ++S G+LMK G K T+IKIDPY+N DAGTM+P +HGE FVL
Sbjct: 2 KYVVVSGGVISGIGKGVLASSTGMLMKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGE DLDLGNYER+L +LT DHNITTGK+YS VI KER+G+YLG TVQ++PH+T+ I
Sbjct: 62 DDGGETDLDLGNYERYLGVTLTKDHNITTGKIYSHVIAKERKGDYLGKTVQIVPHLTNAI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ I +A+ D+ ++E+GGTVGDIES PF+EA RQ Q + G+EN A +HV+
Sbjct: 122 QDWIERVAKIPVDDTGMEPDVCIIELGGTVGDIESAPFVEALRQFQFKVGKENFALIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP + GEQKTKPTQ ++K LRSLG+ PD I R + L++ KI++F +V E V
Sbjct: 182 LVPVIH--GEQKTKPTQAAIKGLRSLGLVPDMIACRCSETLDKPTIDKIAMFCHVGPEQV 239
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLED---REPDLREWEKMVAKYKAL------ 285
++ +DV TY VPLLL + + YL RL L++ E + + ++++K+KA
Sbjct: 240 VNVHDVNSTYHVPLLLLEQKMIDYLHARLKLDEISLTEEEKQRGLELLSKWKATTGNFDE 299
Query: 286 -QDSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTK------ 338
++V+I +VGKY L DSYLS+ +AL+H+S+ K+ I+W+EA D+E +
Sbjct: 300 SMETVKIRLVGKYTNLKDSYLSVIKALEHSSMKCRRKLDIKWVEATDLEPEAQESNKTKF 359
Query: 339 -----LLEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVL 393
++ DGI++PGGFG RG EG ++ R+AREN IPFLG+C G Q+ +EF R+ L
Sbjct: 360 HEAWNMVSTADGILIPGGFGVRGTEGMVLAARWARENHIPFLGVCLGLQIATIEFTRSSL 419
Query: 394 GMKGAHSTEIDPQTPYP--VVDLMPEQRNLDK--LGGTMRLGAYPVKIKKGTLAYELYK- 448
G K +HS E P VV MPE +DK +GG+MRLG P + T ++ K
Sbjct: 420 GRKDSHSAEFYPDIDEKNHVVVFMPE---IDKETMGGSMRLGLRPTFFQNETEWSQIKKL 476
Query: 449 ---KDLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFH 505
V+ERHRHR+E+NP ++ E GL+F G D +R EILEL + Y+IATQ+H
Sbjct: 477 YGDVSEVHERHRHRYEINPKMVDELENNGLIFVG-KDDTGKRCEILELKNHPYYIATQYH 535
Query: 506 PEFKSRPMKPAPVFHGLVKAAKEYKQE 532
PE+ S+ + P+ F GLV A+ Q+
Sbjct: 536 PEYTSKVLDPSKPFLGLVAASAGILQD 562
>pir||A72103 ctp synthetase - Chlamydophila pneumoniae (strain CWL029)
>gi|4376510|gb|AAD18389.1| (AE001609) CTP Synthetase
[Chlamydophila pneumoniae CWL029]
Length = 537
Score = 498 bits (1269), Expect = e-140
Identities = 261/539 (48%), Positives = 365/539 (67%), Gaps = 10/539 (1%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K IF+TGGVVS LGKG+T+AS+ L+++ + +K+DPY+N D GTMNP++HGE++V
Sbjct: 4 KCIFLTGGVVSSLGKGLTAASLALILERQRLNVAMLKLDPYLNVDPGTMNPFEHGEIYVT 63
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDG E DLDLG+Y RF +L+ + T+G++Y+ VI++ER G+YLG+TVQVIPHIT+EI
Sbjct: 64 DDGVETDLDLGHYHRFSSAALSRHSSATSGQIYARVIKREREGDYLGSTVQVIPHITNEI 123
Query: 123 KRRIREIARNY--DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
+ I + A+ + D+++VEIGGT+GDIES+PFLEA RQ + + E+ +H+TYVP L+
Sbjct: 124 IQVILDAAKEHSPDVLIVEIGGTIGDIESLPFLEAIRQFRYDHS-EDCLNIHMTYVPYLQ 182
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
E K+KPTQHSV+ LR +GI PDAI+ RSE PL + + KISLF NVP AV + DV
Sbjct: 183 AADEVKSKPTQHSVQTLRGIGIIPDAILCRSEKPLTQEVKSKISLFCNVPNRAVFNVIDV 242
Query: 241 EDT-YEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVK 299
+ T YE+PL+L +E + ++ ++L L +L +W+ +V + V+I +VGKYV+
Sbjct: 243 KHTIYEMPLMLAQEKIANFIGEKLKLATVPENLDDWKVLVNQLSQDLPKVKIGVVGKYVQ 302
Query: 300 LTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEG 359
D+Y SI EAL HA++ +I I+AED E+ T L D +VPGGFG RG EG
Sbjct: 303 HRDAYKSIFEALTHAALRLGHAAEIIPIDAED--ENLTMELSQCDACLVPGGFGVRGWEG 360
Query: 360 KIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQR 419
KI ++ RE IP+ GIC G Q+ VVE+ARNVL + A+S E+DP TP+P+V +M Q
Sbjct: 361 KIAAAKFCREQGIPYFGICLGMQVLVVEYARNVLNLDQANSLEMDPNTPHPIVYVMEGQD 420
Query: 420 NLDKLGGTMRLGAYPVKIKKGTLAYELY-KKDLVYERHRHRWEVNPDYIEAFEKAGLVFS 478
L GGTMRLGAYP +K G+ A++ Y + L+ ERHRHR+EVNPDYI++ E GL
Sbjct: 421 PLVATGGTMRLGAYPCLLKPGSKAHKAYNESSLIQERHRHRYEVNPDYIQSLEDHGLRIV 480
Query: 479 GIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEKDATH 537
G + EI+E+ D + I QFHPEF S+ + P P+F ++AA Y KDA+H
Sbjct: 481 GTC-PPQGLCEIIEVSDHPWMIGVQFHPEFVSKLISPHPLFIAFIEAALVY--SKDASH 536
>pir||E81568 CTP synthase CP0526 [imported] - Chlamydophila pneumoniae (strain
AR39) >gi|7189440|gb|AAF38350.1| (AE002211) CTP synthase
[Chlamydophila pneumoniae AR39]
>gi|8978609|dbj|BAA98446.1| (AP002545) CTP synthetase
[Chlamydophila pneumoniae J138]
Length = 537
Score = 498 bits (1268), Expect = e-140
Identities = 261/539 (48%), Positives = 364/539 (67%), Gaps = 10/539 (1%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K IF+TGGVVS LGKG+T+AS+ L+++ + +K+DPY+N D GTMNP++HGE++V
Sbjct: 4 KCIFLTGGVVSSLGKGLTAASLALILERQRLNVAMLKLDPYLNVDPGTMNPFEHGEIYVT 63
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDG E DLDLG+Y RF +L+ + T+G++Y+ VI++ER G+YLG+TVQVIPHIT+EI
Sbjct: 64 DDGVETDLDLGHYHRFSSAALSRHSSATSGQIYARVIKREREGDYLGSTVQVIPHITNEI 123
Query: 123 KRRIREIARNY--DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
+ I + A+ + D+++VEIGGT+GDIES+PFLEA RQ + + E+ +H+TYVP L+
Sbjct: 124 IQVILDAAKEHSPDVLIVEIGGTIGDIESLPFLEAIRQFRYDHS-EDCLNIHMTYVPYLQ 182
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
E K+KPTQHSV+ LR +GI PDAI+ RSE PL + + KISLF NVP AV + DV
Sbjct: 183 AADEVKSKPTQHSVQTLRGIGIIPDAILCRSEKPLTQEVKSKISLFCNVPNRAVFNVIDV 242
Query: 241 EDT-YEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVK 299
+ T YE+PL+L +E + ++ ++L L +L +W +V + V+I +VGKYV+
Sbjct: 243 KHTIYEMPLMLAQEKIANFIGEKLKLATVPENLDDWRVLVNQLSQDLPKVKIGVVGKYVQ 302
Query: 300 LTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEG 359
D+Y SI EAL HA++ +I I+AED E+ T L D +VPGGFG RG EG
Sbjct: 303 HRDAYKSIFEALTHAALRLGHAAEIIPIDAED--ENLTMELSQCDACLVPGGFGVRGWEG 360
Query: 360 KIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQR 419
KI ++ RE IP+ GIC G Q+ VVE+ARNVL + A+S E+DP TP+P+V +M Q
Sbjct: 361 KIAAAKFCREQGIPYFGICLGMQVLVVEYARNVLNLDQANSLEMDPNTPHPIVYVMEGQD 420
Query: 420 NLDKLGGTMRLGAYPVKIKKGTLAYELY-KKDLVYERHRHRWEVNPDYIEAFEKAGLVFS 478
L GGTMRLGAYP +K G+ A++ Y + L+ ERHRHR+EVNPDYI++ E GL
Sbjct: 421 PLVATGGTMRLGAYPCLLKPGSKAHKAYNESSLIQERHRHRYEVNPDYIQSLEDHGLRIV 480
Query: 479 GIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEKDATH 537
G + EI+E+ D + I QFHPEF S+ + P P+F ++AA Y KDA+H
Sbjct: 481 GTC-PPQGLCEIIEVSDHPWMIGVQFHPEFVSKLISPHPLFIAFIEAALVY--SKDASH 536
>gi|6322563 CTP synthase; Ura8p [Saccharomyces cerevisiae]
>gi|1071917|pir||S57124 CTP synthase (EC 6.3.4.2) URA8
[validated] - yeast (Saccharomyces cerevisiae)
>gi|1015810|emb|CAA89633.1| (Z49603) ORF YJR103w
[Saccharomyces cerevisiae]
Length = 564
Score = 493 bits (1255), Expect = e-138
Identities = 262/563 (46%), Positives = 362/563 (63%), Gaps = 45/563 (7%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ V+GGV+SG+GKG+ ++S G+L+K G K T+IKIDPY+N DAGTM+P +HGE FVL
Sbjct: 2 KYVVVSGGVISGIGKGVLASSTGMLLKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGE DLDLGNYER+L +L+ DHNITTGK+YS VI +ERRG+YLG TVQ++PH+T+ I
Sbjct: 62 DDGGETDLDLGNYERYLGITLSRDHNITTGKIYSHVISRERRGDYLGKTVQIVPHLTNAI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ I+ +++ D+ ++E+GGTVGDIES PF+EA RQ Q E GREN A +HV+
Sbjct: 122 QDWIQRVSKIPVDDTGLEPDVCIIELGGTVGDIESAPFVEALRQFQFEVGRENFALIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP + GEQKTKPTQ ++K+LRSLG+ PD I R + L KI++F +V E V
Sbjct: 182 LVPVIH--GEQKTKPTQAAIKDLRSLGLIPDMIACRCSEELNRSTIDKIAMFCHVGPEQV 239
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKR-------LGLEDREPD---LREWEKMVAKYKA 284
++ +DV TY VPLLL ++ + YL R L LED+E L WE M
Sbjct: 240 VNVHDVNSTYHVPLLLLKQHMIDYLHSRLKLGEVPLTLEDKERGSQLLTNWENMTKNLDD 299
Query: 285 LQDSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKL----- 339
D V+IA+VGKY L DSYLS+ ++L+HAS+ +++I W+EA ++E ++
Sbjct: 300 SDDVVKIALVGKYTNLKDSYLSVTKSLEHASMKCRRQLEILWVEASNLEPETQEVDKNKF 359
Query: 340 ------LEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVL 393
L DGI+VPGGFG RG EG I+ ++ARE+ +PFLG+C G Q+ +EFARNV+
Sbjct: 360 HDSWNKLSSADGILVPGGFGTRGIEGMILAAKWARESGVPFLGVCLGLQVAAIEFARNVI 419
Query: 394 GMKGAHSTEIDPQT----PYPVVDLMPEQRNLDK--LGGTMRLGAYPVKIKKGTLAYELY 447
G + STE +T VV MPE +DK +GGTMRLG P + + +
Sbjct: 420 GRPNSSSTEFLDETLLAPEDQVVIYMPE---IDKEHMGGTMRLGLRPTIFQPNSEWSNIR 476
Query: 448 K----KDLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQ 503
K + V+ERHRHR+E+NP + E G +F G + +R EI EL Y++ TQ
Sbjct: 477 KLYGEVNEVHERHRHRYEINPKIVNDMESRGFIFVG-KDETGQRCEIFELKGHPYYVGTQ 535
Query: 504 FHPEFKSRPMKPAPVFHGLVKAA 526
+HPE+ S+ ++P+ F GLV AA
Sbjct: 536 YHPEYTSKVLEPSRPFWGLVAAA 558
>pir||C71342 probable CTP synthase (pyrG) - syphilis spirochete
>gi|3322579|gb|AAC65292.1| (AE001210) CTP synthase
(pyrG) [Treponema pallidum]
Length = 577
Score = 491 bits (1251), Expect = e-138
Identities = 265/574 (46%), Positives = 345/574 (59%), Gaps = 46/574 (8%)
Query: 4 FIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVLD 63
FIF+TGGVVS LGKGI + +IGLL+K+RG N K DPY+N D GTMNPYQHGEVFV
Sbjct: 5 FIFITGGVVSSLGKGIAAGAIGLLLKSRGISVVNQKFDPYLNGDPGTMNPYQHGEVFVTQ 64
Query: 64 DGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEIK 123
DGGE DLDLG+YERF D + ++ T G VY ++++ER G Y GATVQVIPH+TDEI+
Sbjct: 65 DGGETDLDLGHYERFTDVPSSRFNSTTAGSVYRAILDRERAGGYGGATVQVIPHVTDEIQ 124
Query: 124 RRIREIARNYD--IVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLRV 181
RIR A +V+ EIGGTVGDIES+PF+EA RQ++ G+E F+H+ VP L
Sbjct: 125 ARIRAAAATTGARVVITEIGGTVGDIESLPFIEAIRQIRRVLGKERCLFIHLGLVPYLPS 184
Query: 182 VGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDVE 241
GE KTKP QHSVKEL LG+QPD I+ RSE + + R+K+SLF NV A++
Sbjct: 185 CGEMKTKPLQHSVKELLGLGVQPDVILCRSERHITDAVREKLSLFCNVERRAIVENVTAR 244
Query: 242 DTYEVPLLLEREGLGKYLVKRLGLED---------------------------------- 267
YEVPLLLE EGLG L +RL L D
Sbjct: 245 SIYEVPLLLEAEGLGALLCERLRLFDTCCGGQVARNLGAGGAQSAVLGAGGTVRTDGGLH 304
Query: 268 ------REPDLREWEKMVAKYKALQDSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVK 321
EPDL W MV + + +A+VGKYV L D+YLS+ EAL A + + +
Sbjct: 305 PAAGQGAEPDLTAWRAMVRALYYPRRELTVALVGKYVSLADAYLSVSEALTAAGICHRAR 364
Query: 322 VKIRWIEAEDI--EEHGTKLLEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICF 379
V +RWI+AE+I + L D +++PGGFG RG EG I + +AR ++P+LGIC
Sbjct: 365 VDMRWIDAEEICSVQDAGHALADADALVIPGGFGVRGIEGMICAVSHARVQNLPYLGICL 424
Query: 380 GFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIKK 439
G Q+ V+EFARNVL + AHS E TP+PVVDL+P + GG++RLG Y + +
Sbjct: 425 GMQIAVIEFARNVLLLASAHSREFAVDTPHPVVDLLPGCVD-TPTGGSLRLGQYRCLLAE 483
Query: 440 GTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYF 499
G+ A LY + V+ERHRHR+ +N Y FE + L G+ D +E++E + +F
Sbjct: 484 GSRARALYGRGEVWERHRHRYGLNAAYRARFEASALRPVGV-DSDCGAVEVVEHGEHPWF 542
Query: 500 IATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEK 533
QFHPEF SRP + P+F LV A E K +
Sbjct: 543 FGVQFHPEFCSRPNRAHPLFRALVAAGLERKDSR 576
>sp|P38627|PYRH_YEAST CTP SYNTHASE 2 (UTP--AMMONIA LIGASE 2) (CTP SYNTHETASE 2)
>gi|440163|emb|CAA48277.1| (X68196) CTP synthase
[Saccharomyces cerevisiae]
Length = 577
Score = 484 bits (1233), Expect = e-136
Identities = 252/557 (45%), Positives = 356/557 (63%), Gaps = 39/557 (7%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K++ V+GGV+SG+GKG+ ++S G+L+K G K T+IKIDPY+N DAGTM+P +HGE FVL
Sbjct: 2 KYVVVSGGVISGIGKGVLASSTGMLLKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGE DLDLGNYER+L +L+ DHNITTGK+YS +I +ERRG+YLG TVQ++PH+T+ I
Sbjct: 62 DDGGETDLDLGNYERYLGITLSRDHNITTGKIYSQLISRERRGDYLGKTVQIVPHLTNAI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ I+ +++ D+ ++E+GGTVGDIES PF+EA RQ Q E GREN A +HV+
Sbjct: 122 QDWIQRVSKIPVDDTGLEPDVCIIELGGTVGDIESAPFVEALRQFQFEVGRENFALIHVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
VP + GEQKTKPTQ ++K+LR LG+ PD I R + L KI++F +V E V
Sbjct: 182 LVPVIH--GEQKTKPTQAAIKDLRLLGLIPDMIACRCSEELNRSTIDKIAMFCHVGPEQV 239
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKR-------LGLEDREPD---LREWEKMVAKYKA 284
++ +DV TY VPLLL ++ + YL R L LED+E L WE M
Sbjct: 240 VNVHDVNSTYHVPLLLLKQHMIDYLHSRLKLGEVPLTLEDKERGSQLLTNWENMTKNLDD 299
Query: 285 LQDSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKL----- 339
D V+IA+VGKY L DSYLS+ ++L+HAS+ +++I W+EA ++E ++
Sbjct: 300 SDDVVKIALVGKYTNLKDSYLSVTKSLEHASMKCRRQLEILWVEASNLEPETQEVDKNKF 359
Query: 340 ------LEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVL 393
L DGI+VPGGFG RG EG I+ ++ARE+ +PFLG+C G Q+ +EFARNV+
Sbjct: 360 HDSWNKLSSADGILVPGGFGTRGIEGMILAAKWARESGVPFLGVCLGLQVAAIEFARNVI 419
Query: 394 GMKGAHSTEIDPQT---PYPVVDLMPEQRNLDKLGGTMRLGAYPVKIKKGTLAYELYK-- 448
G + STE +T P + + + + +GGTMRLG P + + + K
Sbjct: 420 GRPNSSSTEFLDETLLAPEDPSSHIHAEIDKEHMGGTMRLGLRPTIFQPNSEWSNIRKLY 479
Query: 449 --KDLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHP 506
+ V+ERHRHR+E+NP + E G +F G + +R EI EL Y++ TQ+HP
Sbjct: 480 GEVNEVHERHRHRYEINPKIVNDMESRGFIFVG-KDETGQRCEIFELKGHPYYVGTQYHP 538
Query: 507 EFKSRPMKPAPVFHGLV 523
E+ S+ ++P+ F GLV
Sbjct: 539 EYTSKVLEPSRPFWGLV 555
>pir||T43732 CTP synthase (EC 6.3.4.2) [imported] - Gibberella zeae (subsp.
graminearum) >gi|3724289|dbj|BAA33767.1| (AB011417)
UTP-ammonia ligase [Gibberella zeae]
Length = 580
Score = 472 bits (1202), Expect = e-132
Identities = 262/557 (47%), Positives = 354/557 (63%), Gaps = 38/557 (6%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K + V+GGV+SG+GKGI ++S GLL+K G + T IK DPYIN DAG +NP +HGE FVL
Sbjct: 2 KVVLVSGGVISGVGKGIIASSAGLLLKTLGLRVTAIKTDPYINTDAGLLNPLEHGECFVL 61
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGE DLDLGNYER+L L+ D NITTGK+Y VIEKERRG+YLG TVQV+PHITD I
Sbjct: 62 DDGGETDLDLGNYERYLGIQLSRDSNITTGKIYKQVIEKERRGDYLGKTVQVVPHITDAI 121
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
+ I +A+ D+ ++E+GGT+GD+ES PF+EA Q++ GR+N + V+
Sbjct: 122 QDWIERVAKIPVDASGEAPDVCIIELGGTIGDLESGPFVEALSQLRHRLGRDNFLSISVS 181
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
YVP + GE+KTKPTQH+++++RS G+ PD I R E L++ KI+ V +E
Sbjct: 182 YVPIIN--GEEKTKPTQHAIRQVRSAGLIPDVIACRCERELDQATITKIARSCQVEDEQA 239
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDRE--PDLRE--------WEKMVAKYKA 284
I +++ Y+VPLLLE+EGL K L K L L+ + P + + W+K V +
Sbjct: 240 IGVRNMDTIYQVPLLLEQEGLLKLLQKGLALDKCQVTPPMAQKGQALWDLWKKTVVPDRH 299
Query: 285 LQDSVEIAIVGKYVKLTDSYLSIKEALKHASVS-----NEVKVKIRWIEAEDIEEHGTKL 339
L + V I +VGKYV L DSYLS+ +AL+H+++ N V V +E E E+ K
Sbjct: 300 L-EPVNIILVGKYVSLDDSYLSVHKALEHSAMRCNRKLNLVSVDSEHLEPEMQEKDPRKF 358
Query: 340 LEG------VDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVL 393
E GIIVPGGFG RG +G + ++ARE +P+LGIC G Q V+E+ARNV+
Sbjct: 359 HEAWAHVVRAQGIIVPGGFGTRGIQGMVDVAKWARERKLPYLGICLGMQTAVIEYARNVM 418
Query: 394 GMKGAHSTEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIKKGTLAYELY----KK 449
G+KGA S E + VV MPE + +++GGTMRLG+ K GT +L
Sbjct: 419 GLKGATSEEFSATAEHRVVIFMPE-GSKEQMGGTMRLGSRTSHFKPGTEWSKLRGLYGGV 477
Query: 450 DLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFK 509
D+V ERHRHR+EVNPDYIE EKAGL + + D R+E +EL D +F+ Q HPE+K
Sbjct: 478 DVVEERHRHRYEVNPDYIEDLEKAGLSLTSM-DDQGVRVETIELKDHPFFVGLQAHPEYK 536
Query: 510 SRPMKPAPVFHGLVKAA 526
S+ + PAP GLV A+
Sbjct: 537 SKTLAPAPSLLGLVAAS 553
>pir||C71695 ctp synthase (pyrG) RP378 - Rickettsia prowazekii
>gi|3860937|emb|CAA14837.1| (AJ235271) CTP SYNTHASE
(pyrG) [Rickettsia prowazekii]
Length = 586
Score = 470 bits (1197), Expect = e-131
Identities = 247/585 (42%), Positives = 352/585 (59%), Gaps = 52/585 (8%)
Query: 1 MTKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVF 60
M +FIFVTGGVVS LGKGIT+AS+ +L++A+G++ + K+DPY+N D GTMNP++HGEV+
Sbjct: 1 MVRFIFVTGGVVSSLGKGITAASLAMLLQAKGFRVSVRKLDPYLNVDPGTMNPHEHGEVY 60
Query: 61 VLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITD 120
V DDG E DLDLG+YERF + NITTG +YS +++ ER G Y G TVQVIPH+T+
Sbjct: 61 VTDDGAETDLDLGHYERFTGVTACKCDNITTGAIYSKLLKDERLGNYTGITVQVIPHVTN 120
Query: 121 EIKRRIREIARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKLR 180
IK I +D ++ EIGGTVGDIE +PF EA RQ+ + N F+H+T +P ++
Sbjct: 121 IIKDFIMSNTNGFDFIICEIGGTVGDIEGLPFFEAIRQIGNKLKNANCLFIHLTLLPYVK 180
Query: 181 VVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYDV 240
E KTKPTQHSVKELR++GI P+ +V R+E + + A KI+LF N+ E VI A D
Sbjct: 181 TARELKTKPTQHSVKELRAIGISPNILVCRAERNISKSAIDKIALFCNIKPEYVIPAIDQ 240
Query: 241 EDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSVEIAIVGKYVKL 300
++ Y VP+ GL ++ + L +W ++ K K V+IAI+ KY K
Sbjct: 241 KNIYLVPIAYHNSGLENKVLNFFNINVVPSKLDKWYDIIDKIKDSNSKVKIAIITKYHKT 300
Query: 301 TDSYLSIKEALKHASVSNEVKVKIRWIEAEDI-EEHGTKLLEGVDGIIVPGGFGARGAEG 359
D+Y S+ EAL HA + + K+ + WI AE++ EE+ K L ++GI+VPGGFG R +G
Sbjct: 301 QDAYKSVIEALNHAGIYYKYKIDVLWINAENLTEENINKKLLDINGILVPGGFGVRATQG 360
Query: 360 KIMTIRYARENDIPFLGICFGFQLTVVEFARNVLG------------------------- 394
K++ I+YAR N+IPF GICFG QL +E A+N++G
Sbjct: 361 KMIAIKYARTNNIPFFGICFGMQLATIEIAQNLIGIQDAVTEEFKIKGTKIIEKINKNCE 420
Query: 395 -----MKGAH--------STEIDPQTPYPVV------------DLMPEQRNLDKLGGTMR 429
+K AH + E D T Y + + RN+ + TMR
Sbjct: 421 DATIKIKNAHISKCTYSEAFECDASTVYTNIHEDSNNLSTDKLQIETNFRNMSDIEKTMR 480
Query: 430 LGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRME 489
LGAYP + T+A YK + ERHRHR++ N ++ FE+ G+VFSG + +++ +E
Sbjct: 481 LGAYPCNLVANTIAANAYKSLEINERHRHRYKFNNEFQNIFEQHGVVFSGFS-QNKQIVE 539
Query: 490 ILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEYKQEKD 534
I+ELP+ R+F+ QFHPEFKS+P + P+F +KA EY + +
Sbjct: 540 IIELPELRWFVGVQFHPEFKSKPFEAHPLFIQFIKATIEYNKSNE 584
>emb|CAB95405.1| (AL359782) possible ctp synthase [Trypanosoma brucei]
Length = 589
Score = 458 bits (1165), Expect = e-128
Identities = 244/553 (44%), Positives = 356/553 (64%), Gaps = 30/553 (5%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV S LGKG+T+++ G L++A GY+ +IKIDPYIN DAG M+PY+HGEV+VL
Sbjct: 27 KYIVVTGGVCSSLGKGVTTSATGALLRAEGYQVCSIKIDPYINMDAGLMSPYEHGEVYVL 86
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGEVDLDLGNYER++ L +HNITTGKVY +I KER+G +LG TVQ++PH T+++
Sbjct: 87 DDGGEVDLDLGNYERWMSVQLRREHNITTGKVYQKLINKERQGGFLGKTVQLVPHFTNDV 146
Query: 123 KRRIREIARN--------YDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
I ++++ +I ++E+GGTVGD+ES PF+EA R+++ G + +H T
Sbjct: 147 VESIFRVSQSPVDESGAQPEICMIELGGTVGDMESQPFVEALRRLRCLVGPDEFCLMHTT 206
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
Y+P G QKTKPTQHS + L S+G+QPD ++ RSE+ L A++K+S V +
Sbjct: 207 YLPVFG--GSQKTKPTQHSTRTLLSMGLQPDILICRSENRLTPDAKEKLSNLCGVRSGDI 264
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDREP--DLREWEKMVAKYKALQD----S 288
+SA +V YEVP++ ++GL LV++L L R P D+ + K L++ +
Sbjct: 265 VSAPNVSCLYEVPVVFTKDGLVDRLVEKLRLVKRTPATDVPRIDTYKTYVKILRNMSNPT 324
Query: 289 VEIAIVGKYVK-LTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE----EHGTKLLEGV 343
V IA VGKY++ D+Y S+ + +H ++ +V++ I ++++E++E + K L G
Sbjct: 325 VRIAFVGKYLQDAGDTYFSVLQCFEHCQIALQVRLDILYVDSEELEGPNADEARKALLGC 384
Query: 344 DGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEI 403
DGI VPGGFG RG +GK + AR N+IP+ G+C G Q+ V+E +RNV+G A+S E
Sbjct: 385 DGIFVPGGFGNRGVDGKCAAAQVARMNNIPYFGVCLGMQVAVIELSRNVVGWSDANSEEF 444
Query: 404 DPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKI-KKGTLAYELY-KKDLVYERHRHRWE 461
+ ++ + VV +M RN K+G M LGA V I +K ++ ++Y K ++V ERHRHR+E
Sbjct: 445 NKESTHQVVRIMDCDRN--KMGANMHLGACDVHIVEKSSIMAKIYSKSNIVVERHRHRYE 502
Query: 462 VNPDYIEAFEKAGLVFSGIAG---DDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPV 518
VN Y E KAGL S + R+E +E P R+F+A QFHPEF S PM PAP
Sbjct: 503 VNTAYFEDLRKAGLCISAVTDPTFSSRCRVEAVENPSLRFFLAVQFHPEFISTPMDPAPT 562
Query: 519 FHGLVKAA--KEY 529
+ + AA K+Y
Sbjct: 563 YLSFMAAAAKKDY 575
>gb|AAF49666.1| (AE003532) CG6854 gene product [alt 2] [Drosophila melanogaster]
Length = 623
Score = 440 bits (1119), Expect = e-122
Identities = 242/494 (48%), Positives = 320/494 (63%), Gaps = 28/494 (5%)
Query: 58 EVFVLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPH 117
EV+VLDDG EVDLDLGNYERFLD +L D+NITTGK+Y VIEKER GEYLG TVQV+PH
Sbjct: 53 EVYVLDDGAEVDLDLGNYERFLDVTLHRDNNITTGKIYKLVIEKERTGEYLGKTVQVVPH 112
Query: 118 ITDEIKRRIREIARNY-------DIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAF 170
ITD I+ + +A+ + +VE+GGT+GDIE MPF+EA RQ Q REN
Sbjct: 113 ITDAIQEWVERVAQTPVQGSSKPQVCIVELGGTIGDIEGMPFVEAFRQFQFRVKRENFCL 172
Query: 171 VHVTYVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVP 230
HV+ VP + GE KTKPTQ SV+ELR G+ PD IV RSE P+ ++KIS F +V
Sbjct: 173 AHVSLVPLPKATGEPKTKPTQSSVRELRGCGLSPDLIVCRSEKPIGLEVKEKISNFCHVG 232
Query: 231 EEAVISAYDVEDTYEVPLLLEREGLGKYLVKRLGL----EDREPDLREWEKMVAKYKALQ 286
+ VI +D+ Y VPLL+E+ G+ +YL +RL L R L++W + + + ++
Sbjct: 233 PDQVICIHDLNSIYHVPLLMEQNGVIEYLNERLQLNIDMSKRTKCLQQWRDLARRTETVR 292
Query: 287 DSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEE------------ 334
V IA+VGKY K TDSY S+ +AL+HA+++ K+++ +IE+ +EE
Sbjct: 293 REVCIAVVGKYTKFTDSYASVVKALQHAALAVNRKLELVFIESCLLEEETLHSEPSKYHK 352
Query: 335 HGTKLLEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLG 394
KL + GI+VPGGFG+RG EGKI ++AREN P LGIC G Q V+EFARN LG
Sbjct: 353 EWQKLCDS-HGILVPGGFGSRGMEGKIRACQWARENQKPLLGICLGLQAAVIEFARNKLG 411
Query: 395 MKGAHSTEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIKKG-TLAYELY-KKDLV 452
+K A++TEIDP T +V MPE + +LGGTMRLG G ++ +LY V
Sbjct: 412 LKDANTTEIDPNTANALVIDMPE-HHTGQLGGTMRLGKRITVFSDGPSVIRQLYGNPKSV 470
Query: 453 YERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRP 512
ERHRHR+EVNP Y+ E+ G+ F G D+ RMEI+EL YF+ATQ+HPE+ SRP
Sbjct: 471 QERHRHRYEVNPKYVHLLEEQGMRFVG-TDVDKTRMEIIELSGHPYFVATQYHPEYLSRP 529
Query: 513 MKPAPVFHGLVKAA 526
+KP+P F GL+ A+
Sbjct: 530 LKPSPPFLGLILAS 543
>pir||T26252 hypothetical protein W06H3.3 - Caenorhabditis elegans
>gi|3880516|emb|CAA16517.1| (AL021572) contains
similarity to Pfam domain: PF00117 (Glutamine
amidotransferase class-I), Score=86.6, E-value=1.7e-22,
N=1 [Caenorhabditis elegans]
Length = 599
Score = 439 bits (1116), Expect = e-122
Identities = 235/521 (45%), Positives = 334/521 (64%), Gaps = 32/521 (6%)
Query: 3 KFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVL 62
K+I VTGGV+SG+GKGI S+S+G+L+K GYK + IKIDPY+N DAGT +PY+HGEVFVL
Sbjct: 8 KYILVTGGVISGVGKGIISSSLGVLLKNNGYKVSAIKIDPYLNEDAGTFSPYEHGEVFVL 67
Query: 63 DDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDEI 122
DDGGEVDLDLGNYERFLD LT D+NITTGK++ V+E+ERRG+Y G TVQ+IPH+TD I
Sbjct: 68 DDGGEVDLDLGNYERFLDIRLTRDNNITTGKMFKHVMERERRGDYCGKTVQMIPHLTDAI 127
Query: 123 KRRIREIAR--------NYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVT 174
I +AR D+ ++E+GGT+GDIE M +L A + Q + ++ VHV+
Sbjct: 128 VDWIERVARIPVDGTSEQPDVCIIELGGTIGDIEGMTYLSAFERFQRPTLKNDLMNVHVS 187
Query: 175 YVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAV 234
+ GE KTKP Q+SV+ LR+ G+ PD ++ RS + L+ R+KI+ F + E V
Sbjct: 188 LILHPNATGEPKTKPMQNSVRHLRAAGLVPDLLICRSTEKLDPHLREKIAGFGMMDLEQV 247
Query: 235 ISAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLRE--------WEKMVAKYKALQ 286
+ +DV + Y+VPLLL+++G+ + + +RL L + ++R+ W + Q
Sbjct: 248 VGVHDVSNIYKVPLLLQQQGVLEAITQRLRLSEISENIRKDLKFNMNHWTNLSELCDTFQ 307
Query: 287 DSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAE------DIEEHGTKLL 340
V IA+VGKYVK+ D+Y S+ +AL HA++ + K+KI ++++E +EE
Sbjct: 308 QVVNIALVGKYVKIADAYASVNKALSHAAIHAKRKLKITYVDSELLENKPGMEEQSRAAW 367
Query: 341 EGV---DGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKG 397
+ V DG+IVPGGF RG EG I Y R+ND+P+LG+C G Q+ +EFARNVL + G
Sbjct: 368 DSVKAADGVIVPGGFDKRGVEGMINAAEYCRKNDVPYLGVCLGMQVAAIEFARNVLSIDG 427
Query: 398 AHSTEIDP---QTPYPVVDLMPEQRNLDK-LGGTMRLG-AYPVKIKKGTLAYELYKKDLV 452
A+STE + + V+D MPE +K LGGTMRLG V + + + LY V
Sbjct: 428 ANSTEFNSKLHENQQIVID-MPEHNVEEKGLGGTMRLGRRSTVFLTDECILHRLYGTHTV 486
Query: 453 YERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILEL 493
ERHRHR+EVNP + + G +F G+ G DE+ +I ++
Sbjct: 487 EERHRHRYEVNPHVVPQMARKGFLFVGM-GVDEQNTDIWDV 526
>gb|AAB41453.1| (U30328) cytidine triphosphate synthetase precursor [Giardia
intestinalis]
Length = 620
Score = 438 bits (1115), Expect = e-122
Identities = 255/617 (41%), Positives = 353/617 (56%), Gaps = 88/617 (14%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
T +IFVTGGV+SG+GKG+ +AS+G+L+K+ GY K DPYIN D G M+PYQHGEVFV
Sbjct: 3 TYYIFVTGGVISGIGKGLFAASLGMLIKSYGYDVVMQKCDPYINVDPGLMSPYQHGEVFV 62
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
DDG E DLDLG+YERFLDT+LT ++TTG +YSTVI++ER G Y G TVQV+P I DE
Sbjct: 63 TDDGAETDLDLGHYERFLDTNLTRLSSVTTGSIYSTVIQREREGGYNGMTVQVVPQIVDE 122
Query: 122 IKRRIR-------------EIARNYD---------IVVVEIGGTVGDIESMPFLEAARQM 159
IK R+R E R + V++EIGGTVGD+ES FLEA RQ+
Sbjct: 123 IKARMRCFELISTVPGENSEPQRKHSAPLASTQKRFVIIEIGGTVGDMESTAFLEAMRQL 182
Query: 160 QLEEGRENVAFVHVTYVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGA 219
+ GR N HV+Y+P L E KTKPTQHSV+ L S+GI+PD +V R++ L +
Sbjct: 183 IDDVGRCNACSFHVSYIPVLSNGKELKTKPTQHSVRTLLSVGIKPDFLVCRTDTHLPKET 242
Query: 220 RKKISLFTNVPEEAVISAYDVEDTYEVPLLLER------EGLGKYLVKRLGLEDREPDLR 273
K++ + ++ VI + V+ Y++PLL++ ++ ++ E L
Sbjct: 243 IAKLAHSCGLSKDHVIENFTVQSIYQLPLLIKHVPALVFNLFNVIPIRATAEKEAEASLD 302
Query: 274 EWEKMVAKY---------KAL-------QDSVEIAIVGKYVKLTDSYLSIKEALKHASVS 317
+W ++V ++ AL + + I +VGKYV+L D+Y+S+ EA+ HA+
Sbjct: 303 KWSEIVERFIHPATLSTGDALACKEYDKKSHIRIGLVGKYVELRDAYISVYEAIHHAAAH 362
Query: 318 NEVKVKIRWIEAEDIE---------------------------------EHGTKLLEGVD 344
+ V I I ++ E T LE VD
Sbjct: 363 SNCYVDILSIVSDTCEGADRASSSTPAPKAQSAEPAKFEEKLHTETSNFVPATVTLENVD 422
Query: 345 GIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEID 404
II+PGGFG+RG GK+ I+Y R+N+ P LGIC G Q +EFA NVL +K A STE D
Sbjct: 423 AIIIPGGFGSRGVSGKLEAIKYCRQNNKPILGICLGMQCMAIEFANNVLNLKDATSTEFD 482
Query: 405 PQTPYPVVDLM---------PEQRNLDK-LGGTMRLGAYPVKIKKGTLAYELYKKDLVYE 454
P+T PV+ + P L + GG+MRLGA + GTLA + Y+ + E
Sbjct: 483 PETTNPVIATIISEDVKAANPLAATLIRGSGGSMRLGACNCTLLNGTLAQKCYQCKNIRE 542
Query: 455 RHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMK 514
RHRHR+E N Y FE+AG+VFSG++ + +EI+E+P +F+ QFHPE SRP+K
Sbjct: 543 RHRHRYEFNGRYKTLFEEAGVVFSGLS-TESSLVEIMEIPSLDFFLGVQFHPELLSRPLK 601
Query: 515 PAPVFHGLVKAAKEYKQ 531
P P+F GL+ AA K+
Sbjct: 602 PHPLFVGLIGAALAKKR 618
>sp|P50547|PYRG_CRIGR CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
>gi|460262|gb|AAA36969.1| (L29453) CTP synthetase
[Cricetulus griseus]
Length = 447
Score = 436 bits (1110), Expect = e-121
Identities = 228/448 (50%), Positives = 302/448 (66%), Gaps = 25/448 (5%)
Query: 41 DPYINYDAGTMNPYQHGEVFVLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIE 100
DPYIN DAGT +PY+HGEVFVLDDGGEVDLDLGNYERFLD LT D+N+TTGK+Y VI
Sbjct: 1 DPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVIN 60
Query: 101 KERRGEYLGATVQVIPHITDEIKRRIR--------EIARNYDIVVVEIGGTVGDIESMPF 152
KER+G+YLG TV V+PHITD I+R + E + V+E+GGTVGDIESMPF
Sbjct: 61 KERKGDYLGKTVHVVPHITDAIQRWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPF 120
Query: 153 LEAARQMQLEEGRENVAFVHVTYVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSE 212
+EA RQ Q + REN +HV+ VP+ GEQKTKPTQ+SV+ELR LG+ PD +V R
Sbjct: 121 IEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCS 180
Query: 213 DPLEEGARKKISLFTNVPEEAVISAYDVEDTYEVPLLLEREGLGKYLVKRLGL---EDRE 269
+PL+ ++KIS+F +V E VI +DV Y VPLLLE +G+ Y ++ L L
Sbjct: 181 NPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRSLELPIERQSR 240
Query: 270 PDLREWEKMVAKYKALQDSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEA 329
L +W++M +Y L ++ IA+VGKY KL+DSY S+ +AL+H++++ K++I++I++
Sbjct: 241 KMLMKWKEMADRYDRLLETCSIALVGKYTKLSDSYASVIKALEHSALAINHKLEIKYIDS 300
Query: 330 EDIE-----------EHGTKLLEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGIC 378
D+E + L G++VPGGFG RG EGKI I +AR+ PFLG+C
Sbjct: 301 TDLEPSTLQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARKQKKPFLGVC 360
Query: 379 FGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIK 438
G QL VVEF+RNVLG + A+STE DP+T +PVV MPE N ++GGTMRLG +
Sbjct: 361 LGMQLAVVEFSRNVLGWQDANSTEFDPKTSHPVVIDMPE-HNPGQMGGTMRLGKSRTLFQ 419
Query: 439 -KGTLAYELY-KKDLVYERHRHRWEVNP 464
K ++ +LY D + ERHRHR+EVNP
Sbjct: 420 TKNSVMSKLYGDTDYLEERHRHRFEVNP 447
>gb|AAC36385.1| (U51645) cytidine triphosphate synthetase [Plasmodium falciparum]
Length = 860
Score = 354 bits (898), Expect = 2e-96
Identities = 195/485 (40%), Positives = 285/485 (58%), Gaps = 81/485 (16%)
Query: 3 KFIFVTGGVVSGLGKGITSAS-IGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
K+I VTGG +SGLGKG + S G ++ + + N K+DPY+N DAGTM+PY+HGEV+V
Sbjct: 12 KYIIVTGGNMSGLGKGTAAMSRYGCIIVNKKHFINNNKVDPYLNIDAGTMSPYEHGEVYV 71
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
L+DGGEVDLDLGNYERFL+ LT+ +NIT+GK+Y VI+KER+GEYLG TVQV+PH+TD
Sbjct: 72 LEDGGEVDLDLGNYERFLNIRLTYKNNITSGKIYEEVIKKERKGEYLGKTVQVVPHVTDA 131
Query: 122 IKR--------RIREIARNYDI---------VVVEIGGTVGDIESMPFLEAARQMQLEEG 164
I++ I+++ + Y+I ++E+GGTVGDIES +LEA +Q+
Sbjct: 132 IQKWIKDVIDENIKKMKKEYNIDSFNKIPCMCLIEVGGTVGDIESAVYLEALQQLINNLN 191
Query: 165 RENVAFVHVTYVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKIS 224
++V H++YVP + + EQKTKPTQHSVK LR G++PD I R E+PL + A KKI+
Sbjct: 192 NDDVCLCHLSYVPIIGNLREQKTKPTQHSVKILREAGLKPDFIFCRCEEPLTQEAIKKIA 251
Query: 225 LFTNVPEEAVISAYDVEDTYEVPLLLEREGLGKYLVKRLGLED---------REPDLREW 275
LF+ V E VIS +D + Y+VPL+L+++ + ++K+L LE+ W
Sbjct: 252 LFSQVKNEHVISLHDTSNVYKVPLILDKQNVCMNVLKKLNLENVVLNNKLQISPYSFNIW 311
Query: 276 EKMVAKYKALQDSVEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIE-- 333
+++ +Y++ + V I IVGKY D+YLSI +L HA + K+ I++I + +
Sbjct: 312 KQLADRYESSSEQVVIGIVGKYTASNDTYLSIISSLVHACLECGFKLVIKYINSSHLSLK 371
Query: 334 ---------------------------------------------------EHGTKLLEG 342
E + L+
Sbjct: 372 QKKQKKNMDWKKKARKYSYENFHENSSTEKIIFVDDTTSDEDYDKKRRIKYEKAWETLKS 431
Query: 343 VDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTE 402
VDG++VPGGFG RG EGK ++ +Y R ++IP+LGIC G Q+ V++ AR L + A+S E
Sbjct: 432 VDGVLVPGGFGTRGIEGKYLSSKYCRLHNIPYLGICLGMQIAVIDVAREYLNV-NANSEE 490
Query: 403 IDPQT 407
+ T
Sbjct: 491 FEDTT 495
Score = 96.3 bits (236), Expect = 7e-19
Identities = 52/125 (41%), Positives = 73/125 (57%), Gaps = 2/125 (1%)
Query: 411 VVDLMPEQRNLDKLGGTMRLGAYPVKI-KKGTLAYELYKKDL-VYERHRHRWEVNPDYIE 468
V+ M E + D GGTMRLG KI K +L Y+ Y ++L +YERHRHR+E+N Y+
Sbjct: 721 VIISMSEFKGDDNKGGTMRLGVKQSKIIDKDSLTYKAYDEELYIYERHRHRYEINTKYVP 780
Query: 469 AFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
E GL F RMEI E+ + +++ QFHPEF SRP K P+F V A+K+
Sbjct: 781 LLEAVGLTFVAKDIHSVPRMEICEIKNLDFYVGVQFHPEFTSRPFKSNPLFLAFVLASKK 840
Query: 529 YKQEK 533
+++
Sbjct: 841 KLKDR 845
>pir||B82910 CTP synthetase UU284 [imported] - Ureaplasma urealyticum
>gi|6899257|gb|AAF30693.1|AE002125_4 (AE002125) CTP
synthetase [Ureaplasma urealyticum]
Length = 542
Score = 347 bits (881), Expect = 2e-94
Identities = 196/542 (36%), Positives = 311/542 (57%), Gaps = 24/542 (4%)
Query: 2 TKFIFVTGGVVSGLGKGITSASIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFV 61
TKFIFVTGGV S LGKG++++SIG ++ GY K+DPY+N D ++P QHGEVFV
Sbjct: 12 TKFIFVTGGVYSSLGKGVSASSIGRILVELGYSVAMQKLDPYLNIDPTYLSPLQHGEVFV 71
Query: 62 LDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIEKERRGEYLGATVQVIPHITDE 121
DG E DLDLG YERF++ L ++T+GK+Y ++ KER + G TVQ IPH+T
Sbjct: 72 TKDGKEADLDLGTYERFINADLNKYASVTSGKIYYEILTKERENGFDGKTVQTIPHVTSA 131
Query: 122 IKRRIREI--ARNYDIVVVEIGGTVGDIESMPFLEAARQMQLEEGRENVAFVHVTYVPKL 179
+ I++I + D ++VEIGGT+GDIES+PF+EA Q + G NV F+H + + +
Sbjct: 132 VIDYIKKIKDSLKTDFIIVEIGGTIGDIESLPFIEAISQFKTIYGVNNVMFIHCSPLIYI 191
Query: 180 RVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNVPEEAVISAYD 239
VGE KTKPTQHSVK LRSLGI D ++ R+ L+E KK++ + + + +AYD
Sbjct: 192 EKVGELKTKPTQHSVKTLRSLGINLDLLLLRTNQKLDEVTIKKLAWSCGLDIDMIFAAYD 251
Query: 240 VEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKAL-QDSVEIAIVGKYV 298
VE Y +P +L +G+ K ++ L + ++ W K + ++ I +VGKYV
Sbjct: 252 VESVYLLPNVLFEQGIHKTILDFFSLPLKNDNINSWIDFTDKITTFKKHNLVIGLVGKYV 311
Query: 299 KLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHG-TKLLEGVDGIIVPGGFGA-RG 356
+L D+Y S+ +L+ A++ + +KI++I+ +++ E+ + L+ ++GI++P G+ +G
Sbjct: 312 ELPDAYKSVLASLELAAIELNIDLKIKYIQPQNLNENNINEELKKINGIVIPSIAGSIKG 371
Query: 357 AEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTPYPVVDLMP 416
G ++ YAR+N+IPFL + G + + EF NVL + P ++L
Sbjct: 372 WPGALLAASYARKNNIPFLAVGTGVNIGIGEFINNVL------------KLPIEFINLGN 419
Query: 417 EQRNLDKLG------GTMRLGAYPVKIKKGTLAYELY-KKDLVYERHRHRWEVNPDYIEA 469
+ K R+G Y I+ T+ ++Y K++ + ERHRH +E N YI
Sbjct: 420 GDFSFLKDAFVKNEIENYRIGEYCSNIQANTITSQIYLKQNQLNERHRHHFEFNNHYINN 479
Query: 470 FEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKEY 529
+ G D +++LE +++ T F+PE+ S+P K P F L+K + +
Sbjct: 480 YFLNQNWKIGAISVDNNYIDVLEYTKNHFYVLTIFNPEYTSKPSKANPYFINLLKMSLKI 539
Query: 530 KQ 531
K+
Sbjct: 540 KE 541
>pir||S48584 hypothetical protein - Mycoplasma capricolum (SGC3) (fragment)
>gi|7438017|pir||S77767 CTP synthase (EC 6.3.4.2) -
Mycoplasma capricolum (fragment)
>gi|950067|emb|CAA83703.1| (Z33022) CTP synthase
[Mycoplasma capricolum]
Length = 362
Score = 316 bits (801), Expect = 4e-85
Identities = 160/360 (44%), Positives = 229/360 (63%), Gaps = 3/360 (0%)
Query: 170 FVHVTYVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEEGARKKISLFTNV 229
FVHV + L E KTKP Q+SVK + SLGIQPD IV RS+ + ++KISLF NV
Sbjct: 2 FVHVVLLLWLAASKEYKTKPIQNSVKAMASLGIQPDVIVCRSDSSSPKDIKEKISLFCNV 61
Query: 230 PEEAVISAYDVEDTYEVPLLLEREGLGKYLVKRLGLEDREPDLREWEKMVAKYKALQDSV 289
P +I A D + Y VPL L ++ L ++++L L+ DL W++ K + +
Sbjct: 62 PITNIIDAIDQDSIYRVPLALAKQNLQDIIIEQLQLKANAIDLTSWKQFNKKIDSSSQEI 121
Query: 290 EIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHG-TKLLEGVDGIIV 348
EI+ VGKY++L D+YLS+ E+LK A K+KIRWI+AE + E ++L+ GI+V
Sbjct: 122 EISFVGKYIELQDAYLSVLESLKIAGWEFNKKIKIRWIQAETLNESNYNEILKNSQGILV 181
Query: 349 PGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTP 408
PGGFG RG EG ++ RYAR+NDIP+LGIC G Q+ + AR++L A STE + T
Sbjct: 182 PGGFGKRGIEGMMLASRYARDNDIPYLGICLGMQIATISIARDLLNWTDADSTEFNKNTT 241
Query: 409 YPVVDLMPEQRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIE 468
+P+ D + + + D +GGT+RLG K++K +L +LY D+ ERHRHR+E N Y +
Sbjct: 242 HPIFDYI-KGIDRDNIGGTLRLGTMVTKLEKDSLVSKLYNSDVALERHRHRYEFNNKYKK 300
Query: 469 AFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
E GL FSGI +++ +E++E+P ++F+A+QFHPEF SRP KP P+F G +KA E
Sbjct: 301 DLESVGLRFSGIY-EEKNLVEVIEMPSLKFFVASQFHPEFTSRPNKPTPLFKGFIKAIIE 359
>gb|AAB35189.1| (S79193) CTP synthetase [Chinese hamsters, lung cell V79, Peptide
Partial, 220 aa, segment 1 of 2] [Cricetulus griseus]
Length = 220
Score = 265 bits (669), Expect = 1e-69
Identities = 130/219 (59%), Positives = 159/219 (72%), Gaps = 8/219 (3%)
Query: 41 DPYINYDAGTMNPYQHGEVFVLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKVYSTVIE 100
DPYIN DAGT +PYQHGEVFVLDDGGEVDLDLGNYERFLD LT D+N+TTGK+Y VI
Sbjct: 1 DPYINIDAGTFSPYQHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVIN 60
Query: 101 KERRGEYLGATVQVIPHITDEIKR--------RIREIARNYDIVVVEIGGTVGDIESMPF 152
KER+G+YLG TV V+PHITD I+R + E + V+E+GGTVGDIESMPF
Sbjct: 61 KERKGDYLGKTVHVVPHITDAIQRWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPF 120
Query: 153 LEAARQMQLEEGRENVAFVHVTYVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSE 212
+EA RQ Q + +EN +HV+ VP+ GEQKTKPTQ+SV+ELR LG+ PD +V R
Sbjct: 121 IEAFRQFQFKVKKENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCS 180
Query: 213 DPLEEGARKKISLFTNVPEEAVISAYDVEDTYEVPLLLE 251
+PL+ ++KIS+F +V E VI +DV Y VPLLLE
Sbjct: 181 NPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLE 219
>gb|AAB35190.1| (S79193) CTP synthetase [Chinese hamsters, lung cell V79, Peptide
Partial, 132 aa, segment 2 of 2] [Cricetulus griseus]
Length = 132
Score = 126 bits (314), Expect = 5e-28
Identities = 67/122 (54%), Positives = 85/122 (68%), Gaps = 3/122 (2%)
Query: 345 GIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEID 404
G++VPGGFG RG EGKI I +AR+ PFLG+C G QL VVEF+RNVLG + A+STE D
Sbjct: 12 GVLVPGGFGVRGTEGKIQAIAWARKQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFD 71
Query: 405 PQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIK-KGTLAYELY-KKDLVYERHRHRWEV 462
+T +PVV MPE N ++GGTMRLG + K ++ +LY D + ERHRHR+EV
Sbjct: 72 RKTSHPVVIDMPE-HNPGQMGGTMRLGKSRTLFQTKNSVMSKLYGDTDYLEERHRHRFEV 130
Query: 463 NP 464
NP
Sbjct: 131 NP 132
>dbj|BAB15204.1| (AK025654) unnamed protein product [Homo sapiens]
Length = 151
Score = 97.5 bits (239), Expect = 3e-19
Identities = 57/114 (50%), Positives = 73/114 (64%), Gaps = 4/114 (3%)
Query: 415 MPEQRNLDKLGGTMRLGAYPVKIK-KGTLAYELYKK-DLVYERHRHRWEVNPDYIEAFEK 472
MPE N LGGTMRLG K + ++ +LY + ERHRHR+EVNP+ I+ FE+
Sbjct: 1 MPEH-NPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRFEVNPNLIKQFEQ 59
Query: 473 AGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAA 526
L F G D +R MEI+EL + YF+ QFHPEF SRPMKP+P + GL+ AA
Sbjct: 60 NDLSFVGQDVDGDR-MEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAA 112
>pir||C83363 hypothetical protein PA2268 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948296|gb|AAG05656.1|AE004652_9
(AE004652) hypothetical protein [Pseudomonas aeruginosa]
Length = 356
Score = 75.7 bits (183), Expect = 1e-12
Identities = 61/244 (25%), Positives = 107/244 (43%), Gaps = 13/244 (5%)
Query: 289 VEIAIVGKYVKLTDSYLSIKEALKHASVSNEVKVKIRWIEAEDIEEHGTKLLEGVDGIIV 348
+ IA+VG + ++ +I AL+ A + +++ W+ ++ + LE DG
Sbjct: 9 LRIALVGDHDPHITAHRAIPLALRLAGEALGLEIAFDWLASDRLPAEPA--LERYDGFWC 66
Query: 349 PGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHSTEIDPQTP 408
G R A+ + I +AR PFLG C GFQ T++EFARN LG + A E P +
Sbjct: 67 VPGSPYRDADAVLRLIAHARGRRRPFLGTCAGFQHTILEFARNALGWQAATHGEEHPHSD 126
Query: 409 YPVVDLMPEQRNLDKLGGTMRLGAYPVKIKKGTLAYELYKKDLVYERHRHRWEVNPDYIE 468
V+ +P + V++ +G+ Y D + + R+ + P +
Sbjct: 127 QAVIAALP---------CALLEAREDVRLLRGSRLALAYAADWIEADYHCRYAIAPRF-- 175
Query: 469 AFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFHPEFKSRPMKPAPVFHGLVKAAKE 528
A E G A + + +EL +F+AT F PE + P+ V+A +
Sbjct: 176 AAELTGGALRASAWSADGAIRAVELEQHPFFVATLFQPERAALAGVLPPLPKAFVEACRT 235
Query: 529 YKQE 532
+++
Sbjct: 236 QRRD 239
>emb|CAB71268.1| (AL138598) putative transferase. [Streptomyces coelicolor A3(2)]
Length = 240
Score = 74.9 bits (181), Expect = 2e-12
Identities = 59/210 (28%), Positives = 92/210 (43%), Gaps = 14/210 (6%)
Query: 326 WIEAEDIEEHGTKLLEGVDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTV 385
WI DI H +L+G DGI V G +G + +R+AREN +PFLG C GF +
Sbjct: 39 WIPTTDI--HDVSVLDGFDGIWVVPGAPYFNQKGVHVAVRHARENGLPFLGTCGGFFSAL 96
Query: 386 VEFARNVLGMKGAHSTEIDPQTPYPVVDLMPEQRNLDKLGGTMRLGAYPVKIKKGTLAYE 445
+E A+NVL + A + DP+ P+V L + R P+ + + +
Sbjct: 97 IEHAQNVLHLPEAAGVDEDPEKLMPLV---------TPLKCSFRGEKAPLTVMENSRLAG 147
Query: 446 LYKKDLVYERHRHRWEVNPDYIEAFEKAGLVFSGIAGDDERRMEILELPDKRYFIATQFH 505
+Y V E + + ++ A + L S A D + LE+ +F+ + F
Sbjct: 148 IYGTTEVEEIFHCDYGLTDTFMNAANQGSLRLS--AWDSDGAPRALEITGHPFFLGSLFQ 205
Query: 506 PEFKSRPMKPAPVFHGLVKAAKEYKQEKDA 535
PE S P + + AA K + DA
Sbjct: 206 PELSSAPGSEHKILKAFL-AAVSAKADTDA 234
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.139 0.397
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 203708156
Number of Sequences: 2977
Number of extensions: 9042183
Number of successful extensions: 22428
Number of sequences better than 1.0e-10: 75
Number of HSP's better than 0.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 22029
Number of HSP's gapped (non-prelim): 83
length of query: 537
length of database: 189,106,746
effective HSP length: 58
effective length of query: 479
effective length of database: 154,394,500
effective search space: 73954965500
effective search space used: 73954965500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 167 (69.5 bits)