BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0245 (PAB0245) DE:OXIDOREDUCTASE (259 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||C75151 oxidoreductase PAB0245 - Pyrococcus abyssi (strain O... 519 e-146 pir||A71192 probable glucose 1-dehydrogenase - Pyrococcus horiko... 443 e-123 gb|AAK41248.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-... 165 4e-40 pir||E72612 hypothetical protein APE1361 - Aeropyrum pernix (str... 147 1e-34 pir||C75217 probable short-chain dehydrogenase/reductase PAB2177... 125 4e-28 pir||C71204 probable dehydrogenase - Pyrococcus horikoshii >gi|3... 116 2e-25 gb|AAK42438.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-... 116 3e-25 emb|CAC11951.1| (AL445065) 3-oxoacyl-[acyl-carrier-protein] redu... 99 6e-20 emb|CAC11351.1| (AL445063) 2, 4-dienoyl-CoA reductase (NADPH) pr... 97 2e-19 sp|O34717|YKUF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN CHEV-MOBA IN... 96 3e-19 emb|CAB69765.1| (AL137187) putative dehydrogenase/reductase [Str... 90 2e-17 dbj|BAB05863.1| (AP001514) 2,4-dienoyl-CoA reductase (NADPH) [Ba... 90 3e-17 sp|P80869|DHG2_BACSU GLUCOSE 1-DEHYDROGENASE II (GLCDH-II) (GDH-... 88 9e-17 emb|CAA74371.1| (Y14043) glucose-1-dehydrogenase [Staphylococcus... 85 8e-16 gb|AAG20295.1| (AE005104) putative oxidoreductase; OxrA [Halobac... 84 1e-15 pir||H72686 probable dehydrogenase APE0912 - Aeropyrum pernix (s... 84 1e-15 pir||D72285 3-oxoacyl-(acyl carrier protein) reductase - Thermot... 84 1e-15 sp|P39484|DHG3_BACME GLUCOSE 1-DEHYDROGENASE III (GLCDH-III) >gi... 84 2e-15 gb|AAD32035.1|AF093787_3 (AF093787) CylG [Streptococcus agalactiae] 83 2e-15 sp|P39483|DHG2_BACME GLUCOSE 1-DEHYDROGENASE II (GLCDH-II) >gi|2... 83 4e-15 sp|P40288|DHG_BACME GLUCOSE 1-DEHYDROGENASE >gi|98132|pir||A3352... 83 4e-15 gb|AAG10092.1|U79570_1 (U79570) glucose dehydrogenase [Bacillus ... 82 5e-15 sp|P51831|FABG_BACSU 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 82 9e-15 gb|AAG30942.1| (AF314502) glucose dehydrogenase [Bacillus subtilis] 82 9e-15 sp|P39485|DHG4_BACME GLUCOSE 1-DEHYDROGENASE IV (GLCDH-IV) >gi|2... 81 1e-14 sp|P12310|DHG_BACSU GLUCOSE 1-DEHYDROGENASE >gi|7430990|pir||D69... 81 2e-14 sp|O07399|FABG_MYCAV 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 81 2e-14 gb|AAC44307.1| (U59433) 3-ketoacyl-acyl carrier protein reductas... 80 2e-14 pir||H75616 oxidoreductase, short-chain dehydrogenase/reductase ... 80 2e-14 pir||S47054 probable dehydrogenase (EC 1.1.1.-) - Xanthobacter s... 80 3e-14 emb|CAC11337.1| (AL445063) probable glucose 1-dehydrogenase [The... 80 3e-14 emb|CAA05517.1| (AJ002527) glucitol-6-phosphate dehydrogenase [C... 80 3e-14 gb|AAD37452.1| (AF074603) putative ketoacyl reductase; NonM [Str... 80 4e-14 pir||D72377 oxidoreductase, short chain dehydrogenase/reductase ... 79 5e-14 sp|P10528|DHGA_BACME GLUCOSE 1-DEHYDROGENASE A >gi|80114|pir||S0... 79 6e-14 sp|P39482|DHG1_BACME GLUCOSE 1-DEHYDROGENASE I (GLCDH-I) >gi|801... 79 6e-14 pir||G75333 3-oxoacyl-acyl carrier protein reductase - Deinococc... 78 8e-14 emb|CAC11810.1| (AL445065) polyketide synthase chain 7 related p... 78 8e-14 dbj|BAB18775.1| (AB045131) NADPH-dependent retinol dehydrogenase... 78 8e-14 sp|P28643|FABG_CUPLA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 78 1e-13 gi|10337605 peroxisomal short-chain alcohol dehydrogenase [Homo ... 78 1e-13 gb|AAF50801.1| (AE003567) CG10672 gene product [Drosophila melan... 78 1e-13 pir||S36090 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus sub... 78 1e-13 pir||T22676 hypothetical protein F54F3.4 - Caenorhabditis elegan... 78 1e-13 sp|P42317|YXJF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PEPT-KATB IN... 77 2e-13 pir||S01227 glucose 1-dehydrogenase (EC 1.1.1.47) B - Bacillus m... 77 2e-13 dbj|BAA91953.1| (AK001870) unnamed protein product [Homo sapiens] 77 2e-13 sp|Q9WYG0|Y325_THEMA HYPOTHETICAL OXIDOREDUCTASE TM0325 >gi|7431... 76 3e-13 gb|AAD38447.1|AF099742_1 (AF099742) putative short-chain dehydro... 76 3e-13 gb|AAD49430.1|AF173833_1 (AF173833) 7-alpha-hydroxysteroid dehyd... 76 5e-13 emb|CAB59447.1| (AL132644) putative oxidoreductase [Streptomyces... 76 5e-13 sp|P71534|FABG_MYCSM 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 75 7e-13 sp|P39640|YWFD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PTA-ROCC INT... 75 7e-13 gb|AAC38801.1| (AF030176) putative short-chain dehydrogenase/red... 75 7e-13 dbj|BAB18777.1| (AB045133) NADPH-dependent retinol dehydrogenase... 75 7e-13 gi|11433956 peroxisomal short-chain alcohol dehydrogenase [Homo ... 75 9e-13 sp|P57432|FABG_BUCAI 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 74 2e-12 sp|P37079|SORD_KLEPN SORBITOL-6-PHOSPHATE 2-DEHYDROGENASE (GLUCI... 73 3e-12 pir||A72395 oxidoreductase, short chain dehydrogenase/reductase ... 73 3e-12 gb|AAF69799.1|AF232010_1 (AF232010) peroxisomal trans 2-enoyl Co... 73 3e-12 pir||S02299 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus meg... 72 6e-12 pir||JC5856 polyketide synthase (EC 2.-.-.-) chain 7 - Actinomad... 72 6e-12 dbj|BAB04651.1| (AP001510) 3-oxoacyl-(acyl-carrier protein) redu... 72 6e-12 sp|P07999|DHGB_BACME GLUCOSE 1-DEHYDROGENASE B 71 1e-11 pir||T51721 sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) ... 71 1e-11 gb|AAF81239.1| (AF263012) putative beta-ketoacyl reductase [Stre... 71 1e-11 emb|CAB95802.1| (AL359949) putative short chain oxidoreductase [... 71 1e-11 emb|CAC11396.1| (AL445063) 3-ketoacyl-acyl carrier protein reduc... 71 1e-11 emb|CAB92206.1| (AL356592) putative oxidoreductase. [Streptomyce... 71 1e-11 sp|Q9X248|FABG_THEMA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 71 2e-11 pir||T36264 probable dehydrogenase - Streptomyces coelicolor >gi... 71 2e-11 gb|AAD42688.1|AF037323_1 (AF037323) D-beta-hydroxybutyrate dehyd... 71 2e-11 gb|AAC95202.1| (AC004561) putative tropinone reductase [Arabidop... 70 2e-11 pir||E81695 3-oxoacyl-(acyl carrier protein) reductase TC0508 [i... 70 2e-11 pir||E83207 probable short-chain dehydrogenase PA3511 [imported]... 70 2e-11 sp|P33207|FABG_ARATH 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 70 3e-11 sp|P38004|FABG_CHLTR 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 70 3e-11 pir||T36782 probable gluconate dehydrogenase - Streptomyces coel... 70 3e-11 pir||D75472 oxidoreductase, short-chain dehydrogenase/reductase ... 70 3e-11 pir||E82748 tropinone reductase XF0913 [imported] - Xylella fast... 70 3e-11 pir||F82954 probable short-chain dehydrogenase PA5524 [imported]... 69 4e-11 dbj|BAB06901.1| (AP001518) 3-oxoacyl-[acyl-carrier protein] redu... 69 4e-11 pir||T32002 hypothetical protein F36H9.3 - Caenorhabditis elegan... 69 5e-11 gb|AAF24130.1|AF129168_3 (AF129168) D-sorbitol-6-phosphate dehyd... 69 5e-11 sp|P16544|ACT3_STRCO PUTATIVE KETOACYL REDUCTASE >gi|80725|pir||... 69 7e-11 sp|Q11020|Y07E_MYCTU PUTATIVE OXIDOREDUCTASE RV1350 >gi|7431079|... 69 7e-11 pir||H70706 probable OXIDOREDUCTASE - Mycobacterium tuberculosis... 69 7e-11 gb|AAC95204.1| (AC004561) putative tropinone reductase [Arabidop... 69 7e-11 gb|AAF69798.1|AF232009_1 (AF232009) peroxisomal trans 2-enoyl Co... 69 7e-11 gb|AAG10026.1|AF282240_10 (AF282240) cyclohexanol dehydrogenase ... 69 7e-11 gi|8923752 peroxisomal trans 2-enoyl CoA reductase; putative sho... 68 9e-11 gb|AAF70104.1|AF257324_5 (AF257324) AknA [Streptomyces galilaeus] 68 9e-11 >pir||C75151 oxidoreductase PAB0245 - Pyrococcus abyssi (strain Orsay) >gi|5457800|emb|CAB49290.1| (AJ248284) OXIDOREDUCTASE [Pyrococcus abyssi] Length = 259 Score = 519 bits (1322), Expect = e-146 Identities = 259/259 (100%), Positives = 259/259 (100%) Query: 1 MRILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSK 60 MRILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSK Sbjct: 1 MRILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSK 60 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL 120 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL Sbjct: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL 120 Query: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL Sbjct: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE Sbjct: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 Query: 241 YMLGSTIVFDGAMTRGVNL 259 YMLGSTIVFDGAMTRGVNL Sbjct: 241 YMLGSTIVFDGAMTRGVNL 259 >pir||A71192 probable glucose 1-dehydrogenase - Pyrococcus horikoshii >gi|3258245|dbj|BAA30928.1| (AP000007) 261aa long hypothetical glucose 1-dehydrogenase [Pyrococcus horikoshii] Length = 261 Score = 443 bits (1126), Expect = e-123 Identities = 207/259 (79%), Positives = 242/259 (92%) Query: 1 MRILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSK 60 M++LITA+SRGIGFN+AKELL KGHEV+I SSN NI AY++L+E+G +HYF+ADL SK Sbjct: 3 MKVLITASSRGIGFNLAKELLNKGHEVTITSSNIRNIENAYKELRELGTVHYFQADLSSK 62 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL 120 +DIK ++K+AW+AMG I+AL+WNAPNV CEPCM HEARY DWLEAALLH+V+PGYITTLL Sbjct: 63 EDIKRMVKDAWDAMGRIEALIWNAPNVKCEPCMVHEARYRDWLEAALLHLVSPGYITTLL 122 Query: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 IQAWLEKK++GV+IYLSSASVLEPMPPL+LADTARAGLVQL KGI+R YGGKGIRAY VL Sbjct: 123 IQAWLEKKIKGVLIYLSSASVLEPMPPLLLADTARAGLVQLTKGITRAYGGKGIRAYVVL 182 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 LGSFDTPGARENLA+IAEERG++++EIW +EVI+RTPLKRTG+WSELGALIDFLLSENAE Sbjct: 183 LGSFDTPGARENLAKIAEERGMSLEEIWRKEVIERTPLKRTGKWSELGALIDFLLSENAE 242 Query: 241 YMLGSTIVFDGAMTRGVNL 259 YM+GSTI+FDGAMTRGVNL Sbjct: 243 YMMGSTILFDGAMTRGVNL 261 >gb|AAK41248.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-1) [Sulfolobus solfataricus] Length = 265 Score = 165 bits (414), Expect = 4e-40 Identities = 99/258 (38%), Positives = 156/258 (60%), Gaps = 3/258 (1%) Query: 2 RILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSK 60 R+L+TA++ GIG IA+ L++G V I+S N D I KA ++++IG + F ADL Sbjct: 9 RVLVTASTEGIGRGIAEAFLREGCNVVISSRNKDKIEKAILEMRKIGPSVWGFPADLTDF 68 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL 120 ++ L+ A + M ID LV N+ N EP E DW A L++++ +T L+ Sbjct: 69 KSLEELVGYALKIMNGIDILVVNSGNPPKEPSYFFENTMEDWEYATKLYLLSAIKLTNLV 128 Query: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 Q +++ + G I +LSS ++ EP LAD RA L+Q+AK +S+ G + +L Sbjct: 129 YQ-YMKAQRWGRIFFLSSWTIKEPQRIFSLADITRAPLIQMAKLLSKELGEYNVNVNVIL 187 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGR-WSELGALIDFLLSENA 239 +GSF+T GA+ +L + AE+ G +D IW+REVI + P+ RTG +ELG+L+ FL S+ A Sbjct: 188 MGSFETEGAKRSLKKYAEKVGQPLDVIWKREVISQIPIGRTGDIKNELGSLLVFLSSDYA 247 Query: 240 EYMLGSTIVFDGAMTRGV 257 Y+ G++I+ DG M+R + Sbjct: 248 GYINGTSILIDGGMSRAI 265 >pir||E72612 hypothetical protein APE1361 - Aeropyrum pernix (strain K1) >gi|5105041|dbj|BAA80355.1| (AP000061) 252aa long hypothetical protein [Aeropyrum pernix] Length = 252 Score = 147 bits (368), Expect = 1e-34 Identities = 91/250 (36%), Positives = 141/250 (56%), Gaps = 9/250 (3%) Query: 9 SRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKE-IG-EIHYFKADLKSKDDIKLL 66 SRG+GF+ A+ L G + I + + + K+ +++ E G ++ DL+ K ++ Sbjct: 5 SRGLGFHAARALASLGCNLVIVARGREALEKSAKEISEGFGVDVEPLVGDLRKKGHVENA 64 Query: 67 IKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQAWLE 126 + A + G +DA+V N+ EP EA + DW+EAA L++ + T+ L +A Sbjct: 65 VIHAVQTFGRVDAVVAAYGNISREPLTLREAEWEDWIEAAALYLAS----TSSLFKALAS 120 Query: 127 -KKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLGSFD 185 + +I LSS +V EPM PLI++D RAGL +L K +R Y + IR ++LGSF Sbjct: 121 YNTAKATVILLSSFTVAEPMDPLIVSDAVRAGLSRLVKSAARLYPDR-IRPILLILGSFK 179 Query: 186 TPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYMLGS 245 TPGA L RIA RG +++ +W REV +PL R+G E +I L+ + +YM G+ Sbjct: 180 TPGAMRTLERIARSRGESLENVWRREVEMLSPLARSGGLDEFEEVIRMLV-RSPDYMHGA 238 Query: 246 TIVFDGAMTR 255 T+VFDGA R Sbjct: 239 TVVFDGASGR 248 >pir||C75217 probable short-chain dehydrogenase/reductase PAB2177 - Pyrococcus abyssi (strain Orsay) >gi|5457695|emb|CAB49186.1| (AJ248283) PUTATIVE SHORT-CHAIN DEHYDROGENASE/REDUCTASE [Pyrococcus abyssi] Length = 263 Score = 125 bits (312), Expect = 4e-28 Identities = 85/254 (33%), Positives = 133/254 (51%), Gaps = 7/254 (2%) Query: 6 TAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG--EIHYFKADLKSKDDI 63 TA+S+GIGF +A+ L K G +V I S N +N+++A EK+KE E+HY ADL DD+ Sbjct: 14 TASSKGIGFGVARVLAKAGADVIILSRNEENLKRAREKIKEESNVEVHYIVADLTKMDDL 73 Query: 64 KLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQA 123 + +KE + +G D ++ G +P E DW EA L + Y+T L+ A Sbjct: 74 ERTVKEL-KNIGEPDIFFFSTG--GPKPGYFMEMSMEDWEEAVKLLLYPAIYLTKALVPA 130 Query: 124 WLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLGS 183 +E+K G IIY +S ++ EP+P + L++ R + L + +++ G KGI ++ G Sbjct: 131 -MERKGFGRIIYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMPGI 189 Query: 184 FDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYML 243 T + A+ G T++E + E PL R G E+G L+ FL S+ Y+ Sbjct: 190 IRTDRMIQLAQDRAKREGKTVEEALQ-EYAKPIPLGRLGEPEEIGYLVAFLASDLGSYIN 248 Query: 244 GSTIVFDGAMTRGV 257 G+ I DG V Sbjct: 249 GAMIPVDGGRLNSV 262 >pir||C71204 probable dehydrogenase - Pyrococcus horikoshii >gi|3258343|dbj|BAA31026.1| (AP000007) 282aa long hypothetical dehydrogenase [Pyrococcus horikoshii] Length = 282 Score = 116 bits (289), Expect = 2e-25 Identities = 80/254 (31%), Positives = 130/254 (50%), Gaps = 7/254 (2%) Query: 6 TAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG--EIHYFKADLKSKDDI 63 TA+S+GIGF +A+ L + G +V I S N +N+++A EK+K E+HY ADL +D+ Sbjct: 33 TASSKGIGFGVARVLARAGADVIILSRNEENLKRAKEKIKSESNVEVHYIVADLTKMEDL 92 Query: 64 KLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQA 123 + IKE + +G D ++ G +P E DW A L + Y+T L+ Sbjct: 93 ERTIKELKD-IGDPDIFFFSTG--GPKPGYFMEMSMEDWEGAVKLLLYPAVYLTKALVPG 149 Query: 124 WLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLGS 183 +E+K G I+Y +S ++ EP+P + L++ R + L + +++ G KGI ++ G Sbjct: 150 -MERKGFGRIVYSTSVAIKEPIPNIALSNVVRIAMAGLVRTLAKELGPKGITVNGIMPGI 208 Query: 184 FDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYML 243 T + A+ G +++E +E PL R G E+G L+ FL SE Y+ Sbjct: 209 IRTDRVIQLAQDRAKREGKSVEEAL-KEYAKPIPLGRLGEPEEIGYLVAFLASELGSYIN 267 Query: 244 GSTIVFDGAMTRGV 257 G+ I DG V Sbjct: 268 GAMIPVDGGRLNSV 281 >gb|AAK42438.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-5) [Sulfolobus solfataricus] Length = 261 Score = 116 bits (288), Expect = 3e-25 Identities = 84/260 (32%), Positives = 136/260 (52%), Gaps = 12/260 (4%) Query: 2 RILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI--GEIHYFKADLKS 59 ++++TAAS+GIG IAK L++G +V I+S++ N+ KAY KLKEI + Y KADL + Sbjct: 9 KVIVTAASKGIGLAIAKRFLEEGAKVIISSNDESNLMKAYNKLKEIHSENVSYIKADLMN 68 Query: 60 KDDIKLLIKEAWEAMGAIDAL--VWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYIT 117 ++K L+ E + +G +D L V +P G ++ + DW++A L +++ Sbjct: 69 PHEVKSLVHEGYRKLGGLDVLAYVTGSPKPGNLFSLSDK----DWMDAFNLLLLS---AV 121 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 + +A + G II +S ++ +P+ L L++ R L L K SR G KGI Sbjct: 122 VAVREAGQLMQSGGRIILSTSTTLRQPIDNLDLSNVVRLSLAGLIKVASRELGPKGILVN 181 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 V+ G T + + A G + DE+ + V D PL R G E+ ++ FL S Sbjct: 182 GVMPGWTKTERLLQIIRDRAIREGKSEDEVLKSIVAD-VPLGRAGEPEEIANVVLFLASN 240 Query: 238 NAEYMLGSTIVFDGAMTRGV 257 + Y+ G+ I DG +GV Sbjct: 241 LSTYVTGALIPVDGGSIKGV 260 >emb|CAC11951.1| (AL445065) 3-oxoacyl-[acyl-carrier-protein] reductase related protein [Thermoplasma acidophilum] Length = 269 Score = 98.7 bits (242), Expect = 6e-20 Identities = 80/256 (31%), Positives = 132/256 (51%), Gaps = 15/256 (5%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLK-EIG-EIHYFKADLKSKD 61 +++AAS GIG IA L + G+ +++ + + I +A ++LK + G E ADL + Sbjct: 22 IVSAASSGIGKGIASVLSRSGYRLTLFARDEKRIDEARKELKLKFGLEPLAIPADLSKPE 81 Query: 62 DIKLLIKEAWEAMGAIDALVWNA--PNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTL 119 DI ++K+ E G+I+ LV N P V ++ E DW A + ++ IT Sbjct: 82 DIDRVVKKHRETYGSIENLVINYGDPRVAGFTDLSDE----DWQYAIDMIFMSTVRITRE 137 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 ++ + + G I+Y++S +V EPM L+ + R+ +V LAK IS GIR T+ Sbjct: 138 ALKDMIRAR-HGSIVYVTSMTVREPMEGFSLSSSLRSAVVALAKNISLEVSKFGIRINTI 196 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G +T R+ + + GV E R + PL+R G E+G +++FLLS A Sbjct: 197 SQGYINTERLRDVI-----KTGVDRTE-GMRRLSGDVPLRRVGDPEEIGEVVEFLLSSRA 250 Query: 240 EYMLGSTIVFDGAMTR 255 Y+ G+ I DG +T+ Sbjct: 251 SYVNGANIPVDGGITK 266 >emb|CAC11351.1| (AL445063) 2, 4-dienoyl-CoA reductase (NADPH) precursor related protein [Thermoplasma acidophilum] Length = 282 Score = 96.7 bits (237), Expect = 2e-19 Identities = 67/249 (26%), Positives = 110/249 (43%), Gaps = 12/249 (4%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 L+T GIGF+I K + G ++I + + A K KE G + + D++ Sbjct: 13 LVTGGGTGIGFSIGKRYGELGASIAICGRRENVLADAVFKFKEAGIDADSHRCDVRDPTQ 72 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQ 122 + + + G ID LV NA P D + +LH Y+T L + Sbjct: 73 VSETVDHFMDRFGKIDVLVNNAAGNFVSPTEKLSPHAFDAVIGIVLHGTV--YMTLELGK 130 Query: 123 AWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLG 182 W+ GV++ + + ++ + A+AG++ L + ++ + GIR + G Sbjct: 131 RWIRNGQHGVVLDIVTTYAWTGSGYVVPSAAAKAGVLALVRSLAVEWAKYGIRHVAIAPG 190 Query: 183 SFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYM 242 F T R+NL I E E ++ R PLKR GR E+ L +L+S+ AEY+ Sbjct: 191 PFPTEATRKNLFPIPEI---------EDRIVQRVPLKRPGRMDEIANLAAYLVSDGAEYI 241 Query: 243 LGSTIVFDG 251 GS + DG Sbjct: 242 NGSVVTIDG 250 >sp|O34717|YKUF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN CHEV-MOBA INTERGENIC REGION >gi|7431064|pir||C69865 glucose 1-dehydrogenase homolog ykuF - Bacillus subtilis >gi|2632227|emb|CAA10869.1| (AJ222587) YkuF protein [Bacillus subtilis] >gi|2633777|emb|CAB13279.1| (Z99111) similar to glucose 1-dehydrogenase [Bacillus subtilis] Length = 254 Score = 96.3 bits (236), Expect = 3e-19 Identities = 70/253 (27%), Positives = 125/253 (48%), Gaps = 17/253 (6%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI-GEIHYFKADLKSKD 61 ++IT S G+G +AK+ + G V + N + + + ++++ G++ F+ D++S Sbjct: 6 VIITGGSSGMGKAMAKKQAELGWHVMVTGRNHEALEETKKEIQTFEGQVACFQMDVRSDS 65 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPG--YITTL 119 +IKEA +A G +DAL+ NA G C A + W A++ IV G + + Sbjct: 66 AASDMIKEAVKAFGRLDALINNA--AGNFICPAEKLTPNGW--KAVIEIVLNGTFFCSQA 121 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGK-GIRAYT 178 + W+++K +GVI+ +++ ++ + A+AG++ L + ++ +G K GIR Sbjct: 122 AARHWIDQKQQGVILNMAATYAWGAGAGVVHSAAAKAGVLSLTRTLAVEWGSKYGIRTNA 181 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 + G + G E L + TM+ + PL R G E+ AL FLLS+ Sbjct: 182 IAPGPIERTGGAEKLFESEKAMARTMNSV---------PLGRLGTPEEIAALAAFLLSDE 232 Query: 239 AEYMLGSTIVFDG 251 A Y+ G I DG Sbjct: 233 ASYINGDCITMDG 245 >emb|CAB69765.1| (AL137187) putative dehydrogenase/reductase [Streptomyces coelicolor A3(2)] Length = 255 Score = 90.1 bits (220), Expect = 2e-17 Identities = 73/254 (28%), Positives = 121/254 (46%), Gaps = 25/254 (9%) Query: 2 RILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKD 61 R L+T +RGIG I + LL+ G EV + R A E + +AD+++ Sbjct: 17 RALVTGGTRGIGAAIVRRLLEAGAEVITTA------RSATGPAPE--GAGFVQADVRTLA 68 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYI----DWLEAALLHIVAPGYIT 117 + L A EA+G +D LV NA G P H+ + +WL+ L+++A + Sbjct: 69 GAEALAGAALEALGGVDILVHNAG--GARP---HKDGLVIPDEEWLDTLNLNLLASVRLN 123 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 +LL+ E++ G I+++SSA+V P PP + A+A L + G++ T G+R Sbjct: 124 SLLVPGMRERRS-GAIVHISSAAVAPPAPPFLHYQAAKAALDNYSAGLAATLAPSGVRVN 182 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 TV G TPG E E ++D PL R G ++ + +L+S+ Sbjct: 183 TVSPGRTATPGGEE-----TREHWASLDA--GPAPSGTAPLGRDGLPDDIAHAVLYLVSD 235 Query: 238 NAEYMLGSTIVFDG 251 A ++ G+++ DG Sbjct: 236 RAGWVTGTSLAVDG 249 >dbj|BAB05863.1| (AP001514) 2,4-dienoyl-CoA reductase (NADPH) [Bacillus halodurans] Length = 257 Score = 89.7 bits (219), Expect = 3e-17 Identities = 62/251 (24%), Positives = 117/251 (45%), Gaps = 13/251 (5%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKL-KEIGEIHYFKADLKSKD 61 I++T S G+G +A G V I + + + A ++ ++ G + + D+++ D Sbjct: 6 IIVTGGSNGMGKAMAARFASLGANVVITGRDQERLETAKSEVAQDSGRVLTVQMDVRNPD 65 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 D++ ++K+ GAID LV NA G C A + W + + + T + Sbjct: 66 DVERMVKDTLSEFGAIDGLVNNA--AGNFLCAAEDLSLNGWKSVIDIVLNGTWHCTQAVG 123 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGK-GIRAYTVL 180 + W++ +G I+ + + ++ + +A+AG++ + + ++ +G K GIR + Sbjct: 124 KEWIKDGRKGHILNMVATYAWTAGAGVVHSASAKAGVLAMTRTLAVEWGTKYGIRLNAIA 183 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 G + G E L ++E +++ V+ PLKR G E+ L +L SE A Sbjct: 184 PGPIEGTGGAEKLI---------LNETFQKAVLQTVPLKRFGTLEEIAGLAAYLFSEEAT 234 Query: 241 YMLGSTIVFDG 251 YM G I DG Sbjct: 235 YMNGECISLDG 245 >sp|P80869|DHG2_BACSU GLUCOSE 1-DEHYDROGENASE II (GLCDH-II) (GDH-II) (GENERAL STRESS PROTEIN 74) (GSP74) >gi|7430991|pir||G69755 glucose 1-dehydrogenase homolog ycdF - Bacillus subtilis >gi|2415734|dbj|BAA22244.1| (AB000617) YcdF [Bacillus subtilis] >gi|2632569|emb|CAB12077.1| (Z99105) similar to glucose 1-dehydrogenase [Bacillus subtilis] Length = 258 Score = 88.2 bits (215), Expect = 9e-17 Identities = 64/253 (25%), Positives = 118/253 (46%), Gaps = 14/253 (5%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIA-SSNPDNIRKAYEKLKEIG-EIHYFKADLKSKD 61 ++T +S+GIG IA+ K+ V + S+P + E +K+ G + +AD+ ++ Sbjct: 11 IVTGSSKGIGKAIAERFGKEKMNVVVNYHSDPSGADETLEIIKQNGGKAVSVEADVSKEE 70 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 I+ L+ A E G +D +V N+ G E M HE DW +++ + Sbjct: 71 GIQALLDTALEHFGTLDVMVNNSGFNGVE-AMPHEMSLEDWQRVIDVNVTGTFLGAKAAL 129 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 ++ ++G ++ +SS P P + T++ G+ + + ++ Y KGIR + Sbjct: 130 NHMMKNNIKGNVLNISSVHQQIPRPVNVQYSTSKGGIKMMTETLALNYADKGIRVNAIAP 189 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEY 241 G+ T E T E ++ + + P+K G+ E+ A +L+SE A Y Sbjct: 190 GTIAT-----------ESNVDTKKEESRQKQLKKIPMKAFGKPEEVAAAAAWLVSEEASY 238 Query: 242 MLGSTIVFDGAMT 254 + G+T+ DG MT Sbjct: 239 VTGATLFVDGGMT 251 >emb|CAA74371.1| (Y14043) glucose-1-dehydrogenase [Staphylococcus xylosus] Length = 263 Score = 85.0 bits (207), Expect = 8e-16 Identities = 66/260 (25%), Positives = 123/260 (46%), Gaps = 24/260 (9%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSI---ASSNPDNIRKAYEKLKEIG----EIHYFKA 55 ++IT S GIG + ++ K+ +V I + S+ D++ ++ + +++ G ++H A Sbjct: 10 VVITGGSSGIGKAMVEQFGKEKAKVVINYLSESSLDDVAESIKLIEDAGGQAIKVH---A 66 Query: 56 DLKSKDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPG 114 D+ ++D+ LIK A + G +D L+ NA G E P HE +W + +++ Sbjct: 67 DVSKEEDVNNLIKAAVDTFGTLDILINNA---GFEKPIPTHEMPLEEWQKVIDINLTGAF 123 Query: 115 YITTLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGI 174 + + +L++ +G+I+ SS P P + ++ GL + + +S Y GI Sbjct: 124 IGSKAAVNQFLKEDKKGIILNTSSVHDRIPWPNYVNYAASKGGLKLMMETMSMEYAQHGI 183 Query: 175 RAYTVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFL 234 R + G+ T RE + D E ++ P K G ++ + FL Sbjct: 184 RINNISPGAIVTEHTREKFS----------DPETRAETLEMIPAKEIGEADQVANVARFL 233 Query: 235 LSENAEYMLGSTIVFDGAMT 254 S+ A+Y+ G+TI DG MT Sbjct: 234 CSDLADYIHGTTIYVDGGMT 253 >gb|AAG20295.1| (AE005104) putative oxidoreductase; OxrA [Halobacterium sp. NRC-1] Length = 261 Score = 84.3 bits (205), Expect = 1e-15 Identities = 72/260 (27%), Positives = 122/260 (46%), Gaps = 16/260 (6%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKL--KEIGEIHYFKADLKSKD 61 ++TA+S G+G A L ++G +V + S + + + A E++ G + AD+ Sbjct: 11 VVTASSSGLGKASAAALAREGADVVVCSRDEERVVAAAEEIGADAAGSVRGVPADITDGA 70 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTL-L 120 D+ +++ A E G +D +V +A V A DW +A L +++ + TL Sbjct: 71 DVAAVVETAVETFGGLDHVVTSAGGVPSGQFTA--VTDDDWTDAFELLVMS--VVRTLDA 126 Query: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 L G + ++S SV EP+ L+L++ R G+V LAK ++R + +RA V Sbjct: 127 AHEHLVAGDGGTVTCITSTSVSEPIEGLVLSNAVRRGVVGLAKTVAREWA-PDVRANVVQ 185 Query: 181 LGSFDTPGARENLARIAEERGVTMDEI----WEREVIDRTPLKRTGRWSELGALIDFLLS 236 G +T E ++ E W EV PL R G SELG ++ FL S Sbjct: 186 PGPHETARIEELVSAAVARGEADSYEAGLAGWSEEV----PLDRLGEPSELGDVVAFLAS 241 Query: 237 ENAEYMLGSTIVFDGAMTRG 256 + A ++ G+++ DG G Sbjct: 242 DRASFVTGASVPVDGGRLWG 261 >pir||H72686 probable dehydrogenase APE0912 - Aeropyrum pernix (strain K1) >gi|5104581|dbj|BAA79896.1| (AP000060) 260aa long hypothetical dehydrogenase [Aeropyrum pernix] Length = 260 Score = 84.3 bits (205), Expect = 1e-15 Identities = 63/251 (25%), Positives = 117/251 (46%), Gaps = 8/251 (3%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI---GEIHYFKADLKSK 60 ++TA S G+GF A EL + G + + S N + + A ++ + ++ D++ Sbjct: 11 VVTAGSSGLGFASALELARNGARLLLFSRNREKLEAAASRIASLVSGAQVDIVAGDIREP 70 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL 120 DI L ++A + +G D LV++ G P E DW E+ L + ++ Sbjct: 71 GDIDRLFEKARD-LGGADILVYSTG--GPRPGRFMELGVEDWDESYRLLARSAVWVGRRA 127 Query: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 + +EK G ++Y+ S ++L P L L++ R ++ + + ++ G+ VL Sbjct: 128 AEQMVEKGW-GRMVYIGSVTLLRPWQDLALSNIMRLPVIGVVRTLALELAPHGVTVNAVL 186 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 T R A G+T++E + + R P+ R G+ EL +++ FL SE A Sbjct: 187 PSLILTDRVRSLAEERARRSGITVEEAL-KSMASRIPMGRVGKPEELASVVAFLASEKAS 245 Query: 241 YMLGSTIVFDG 251 ++ G+ I DG Sbjct: 246 FITGAVIPVDG 256 >pir||D72285 3-oxoacyl-(acyl carrier protein) reductase - Thermotoga maritima (strain MSB8) >gi|4981718|gb|AAD36244.1|AE001774_1 (AE001774) 3-oxoacyl-(acyl carrier protein) reductase [Thermotoga maritima] Length = 237 Score = 84.3 bits (205), Expect = 1e-15 Identities = 74/257 (28%), Positives = 127/257 (48%), Gaps = 36/257 (14%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDD 62 +L+ AASRGIG +A L ++G EV+I + N + ++++ + Y DL+ D Sbjct: 10 VLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSGHR--------YVVCDLRK--D 59 Query: 63 IKLLIKEAWEAMGAIDALVWNA--PNVGCEPCMAHE--ARYIDWLEAALLHIVAPGYITT 118 + LL ++ E +D LV NA P G + +E ID L ++ IV Y+ Sbjct: 60 LDLLFEKVKE----VDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVR-NYLPA 114 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 + + W G I+ ++S SV+ P+ L +++AR L K +S GI Sbjct: 115 MKEKGW------GRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNC 168 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 V G +T +E L+ EE+ +++V + P++R + E+ +++ FL SE Sbjct: 169 VAPGWTETERVKELLS---EEK--------KKQVESQIPMRRMAKPEEIASVVAFLCSEK 217 Query: 239 AEYMLGSTIVFDGAMTR 255 A Y+ G TIV DG +++ Sbjct: 218 ASYLTGQTIVVDGGLSK 234 >sp|P39484|DHG3_BACME GLUCOSE 1-DEHYDROGENASE III (GLCDH-III) >gi|2117440|pir||I40224 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium >gi|216376|dbj|BAA01475.1| (D10625) glucose dehydrogenase [Bacillus megaterium] Length = 261 Score = 83.9 bits (204), Expect = 2e-15 Identities = 65/258 (25%), Positives = 121/258 (46%), Gaps = 20/258 (7%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI----GEIHYFKADLK 58 ++IT S G+G +A ++ +V I N N +A + KE+ G+ + D+ Sbjct: 10 VVITGGSTGLGRAMAVRFGQEEAKVVINYYN--NEEEALDAKKEVEEAGGQAIIVQGDVT 67 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYIT 117 ++D+ L++ A + G +D ++ NA G E P +HE +W + ++ + Sbjct: 68 KEEDVVNLVQTAIKEFGTLDVMINNA---GVENPVPSHELSLDNWNKVIDTNLTGAFLGS 124 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 I+ ++E ++G +I +SS + P P + ++ G+ Q+ + ++ Y KGIR Sbjct: 125 REAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKQMTETLALEYAPKGIRVN 184 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 + G+ +TP E A D + +V P+ G+ E+ A+ FL S Sbjct: 185 NIGPGAMNTPINAEKFA----------DPVQRADVESMIPMGYIGKPEEVAAVAAFLASS 234 Query: 238 NAEYMLGSTIVFDGAMTR 255 A Y+ G T+ DG MT+ Sbjct: 235 QASYVTGITLFADGGMTK 252 >gb|AAD32035.1|AF093787_3 (AF093787) CylG [Streptococcus agalactiae] Length = 240 Score = 83.5 bits (203), Expect = 2e-15 Identities = 68/252 (26%), Positives = 120/252 (46%), Gaps = 21/252 (8%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDDI 63 ++T +RGIG I KEL K+G++V IA N N KA +E+ ++ +K ++ + Sbjct: 5 IVTGGTRGIGRAITKELYKEGYKV-IAIYN-SNDAKARALQEELPKLDVYKCNISDAKAV 62 Query: 64 KLLIKEAWEAMGAIDALVWNAPNV--GCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 + L+ + + G ID LV NA V G M+ E W++ ++I+ ++ ++ Sbjct: 63 QKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEK----WMDVININIMGLVNMSKAVL 118 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 + K+++G +I +SS S + + ++ + K +++ + GI V Sbjct: 119 KIMKAKRIQGKVINISSTSGIAGQIGQANYSATKGAIISITKTLAKEFASDGITINCVSP 178 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEY 241 G +T E + +E+ E + PLKR G+ E+ L+ FL SE A Y Sbjct: 179 GFIETDMTNELQNK---------EELKEHLI----PLKRFGQPEEVAWLVSFLASEKANY 225 Query: 242 MLGSTIVFDGAM 253 + G IV DG M Sbjct: 226 ITGKNIVIDGGM 237 >sp|P39483|DHG2_BACME GLUCOSE 1-DEHYDROGENASE II (GLCDH-II) >gi|2117439|pir||I39853 glucose 1-dehydrogenase (EC 1.1.1.47) 2 - Bacillus megaterium >gi|216270|dbj|BAA14100.1| (D90044) glucose dehydrogenase [Bacillus megaterium] >gi|228658|prf||1808263D glucose dehydrogenase II [Bacillus megaterium] Length = 261 Score = 82.7 bits (201), Expect = 4e-15 Identities = 65/259 (25%), Positives = 122/259 (47%), Gaps = 22/259 (8%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVS-IASSNPDNIRKAYEKLKEI----GEIHYFKADL 57 +++T S+G+G +A ++ G E S + + N +A E KEI G+ + D+ Sbjct: 10 VVVTGGSKGLGRAMA---VRFGQEQSKVVVNYRSNEEEALEVKKEIEEAGGQAIIVRGDV 66 Query: 58 KSKDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYI 116 ++D+ L++ A + G++D ++ NA G E P +HE +W + ++ Sbjct: 67 TKEEDVVNLVETAVKEFGSLDVMINNA---GVENPVPSHELSLENWNQVIDTNLTGAFLG 123 Query: 117 TTLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRA 176 + I+ ++E ++G +I +SS + P P + ++ G+ + + ++ Y KGIR Sbjct: 124 SREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRV 183 Query: 177 YTVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLS 236 + G+ DTP E A D +V P+ G+ E+ ++ FL S Sbjct: 184 NNIGPGAIDTPINAEKFA----------DPEQRADVESMIPMGYIGKPEEIASVAAFLAS 233 Query: 237 ENAEYMLGSTIVFDGAMTR 255 A Y+ G T+ DG MT+ Sbjct: 234 SQASYVTGITLFADGGMTK 252 >sp|P40288|DHG_BACME GLUCOSE 1-DEHYDROGENASE >gi|98132|pir||A33528 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium >gi|142975|gb|AAA22475.1| (J04805) glucose dehydrogenase (EC 1.1.1.47) [Bacillus megaterium] Length = 261 Score = 82.7 bits (201), Expect = 4e-15 Identities = 65/256 (25%), Positives = 117/256 (45%), Gaps = 16/256 (6%) Query: 3 ILITAASRGIGFNIA-KELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSK 60 ++IT +S G+G ++A + +K V S D E++K++G E K D+ + Sbjct: 10 VVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKGDVTVE 69 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYITTL 119 D+ L++ A + G +D ++ NA G E P +HE DW + ++ + Sbjct: 70 SDVINLVQSAIKEFGKLDVMINNA---GLENPVSSHEMSLSDWNKVIDTNLTGAFLGSRE 126 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 I+ ++E ++G +I +SS P P + ++ G+ + + ++ Y KGIR + Sbjct: 127 AIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNI 186 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G+ +TP E A D +V P+ G E+ A+ +L S A Sbjct: 187 GPGAINTPINAEKFA----------DPEQRADVESMIPMGYIGEPEEIAAVAAWLASSEA 236 Query: 240 EYMLGSTIVFDGAMTR 255 Y+ G T+ DG MT+ Sbjct: 237 SYVTGITLFADGGMTQ 252 >gb|AAG10092.1|U79570_1 (U79570) glucose dehydrogenase [Bacillus licheniformis] Length = 261 Score = 82.3 bits (200), Expect = 5e-15 Identities = 66/255 (25%), Positives = 114/255 (43%), Gaps = 14/255 (5%) Query: 3 ILITAASRGIGFNIAKEL-LKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSK 60 ++IT A G+G +A +K + V +N + EK++ G + D+ + Sbjct: 10 VVITGAGTGLGKAMALRFGAEKANVVINYFKEEENPEETVEKIESSGARAIAVQGDVSKE 69 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL 120 DD+K LI++A ++ G++D +V NA P + + DW ++ Sbjct: 70 DDVKALIRQAVDSFGSVDVMVNNAGVENEVP--SEDLALEDWNRVISTNLTGMFLGCREA 127 Query: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 I L+ ++G +I +SS P P + ++ G L + ++ Y KGIR + Sbjct: 128 IGYMLDHNIKGSVINMSSVHQQIPWPHFVHYAASKGGAKLLTETLALEYAPKGIRVNAIG 187 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 G+ DTP E A D ++ VI+ P+ G+ E+ A +L SE A Sbjct: 188 PGAIDTPINAEKFA----------DPELKKGVIELIPIGYIGKPEEVAACAAWLASEEAS 237 Query: 241 YMLGSTIVFDGAMTR 255 Y+ G T+ DG MT+ Sbjct: 238 YVTGLTLYVDGGMTK 252 >sp|P51831|FABG_BACSU 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) >gi|7430984|pir||A69621 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) [validated] - Bacillus subtilis >gi|2633963|emb|CAB13464.1| (Z99112) 3-ketoacyl-acyl carrier protein reductase [Bacillus subtilis] Length = 246 Score = 81.5 bits (198), Expect = 9e-15 Identities = 68/252 (26%), Positives = 117/252 (45%), Gaps = 17/252 (6%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIA-SSNPDNIRKAYEKLKEIG-EIHYFKADLKSKD 61 ++T ASRGIG +IA +L K G V + S N + +++K +G + KAD+ + + Sbjct: 8 IVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIAVKADVSNPE 67 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 D++ +IKE ID LV NA M + +W + +++ + T + Sbjct: 68 DVQNMIKETLSVFSTIDILVNNAGITRDNLIM--RMKEDEWDDVININLKGV-FNCTKAV 124 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 + K+ G II +SS + P A+AG++ L K ++ + I + Sbjct: 125 TRQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASRNITVNAIAP 184 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEY 241 G T + LA+ ++ E++ + PL R G S++ +++ FL SE A Y Sbjct: 185 GFISTD-MTDKLAKDVQD-----------EMLKQIPLARFGEPSDVSSVVTFLASEGARY 232 Query: 242 MLGSTIVFDGAM 253 M G T+ DG M Sbjct: 233 MTGQTLHIDGGM 244 >gb|AAG30942.1| (AF314502) glucose dehydrogenase [Bacillus subtilis] Length = 261 Score = 81.5 bits (198), Expect = 9e-15 Identities = 65/256 (25%), Positives = 115/256 (44%), Gaps = 16/256 (6%) Query: 3 ILITAASRGIGFNIA-KELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSK 60 ++IT +S G+G +A + K V S D E++K++G E K D+ + Sbjct: 10 VVITGSSTGLGKAMAIRFATAKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKGDVTVE 69 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYITTL 119 D+ L++ A + G +D ++ NA G E P +HE DW++ ++ + Sbjct: 70 SDVINLVQSAIKEFGKLDVMINNA---GLENPVSSHEMSLSDWIKVIDTNLTGAFLGSRE 126 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 I+ ++E ++G +I +SS P P + ++ G+ + + ++ Y KGIR + Sbjct: 127 AIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNI 186 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G+ +TP E A D +V P+ G E A+ +L S A Sbjct: 187 GPGAINTPINAEKFA----------DPEQSADVESMIPMGYIGEPEETAAVAAWLASSEA 236 Query: 240 EYMLGSTIVFDGAMTR 255 Y+ G T+ DG MT+ Sbjct: 237 SYVTGITLFADGGMTQ 252 >sp|P39485|DHG4_BACME GLUCOSE 1-DEHYDROGENASE IV (GLCDH-IV) >gi|2117441|pir||I40225 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium >gi|216378|dbj|BAA01476.1| (D10626) glucose dehydrogenase [Bacillus megaterium] Length = 261 Score = 81.1 bits (197), Expect = 1e-14 Identities = 64/258 (24%), Positives = 120/258 (45%), Gaps = 20/258 (7%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI----GEIHYFKADLK 58 ++IT S G+G +A ++ +V I N N +A + KE+ G+ + D+ Sbjct: 10 VVITGGSTGLGRAMAVRFGQEEAKVVINYYN--NEEEALDAKKEVEEAGGQAIIVQGDVT 67 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYIT 117 ++D+ L++ A + G +D ++ NA G E P +HE +W + ++ + Sbjct: 68 KEEDVVNLVQTAIKEFGTLDVMINNA---GVENPVPSHELSLDNWNKVIDTNLTGAFLGS 124 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 I+ ++E ++G +I +SS + P P + ++ G+ + + ++ Y KGIR Sbjct: 125 REAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 184 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 + G+ +TP E A D + +V P+ G+ E+ A+ FL S Sbjct: 185 NIGPGAMNTPINAEKFA----------DPVQRADVESMIPMGYIGKPEEVAAVAAFLASS 234 Query: 238 NAEYMLGSTIVFDGAMTR 255 A Y+ G T+ DG MT+ Sbjct: 235 QASYVTGITLFADGGMTK 252 >sp|P12310|DHG_BACSU GLUCOSE 1-DEHYDROGENASE >gi|7430990|pir||D69629 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus subtilis >gi|1805462|dbj|BAA09024.1| (D50453) glucose dehydrogenase [Bacillus subtilis] >gi|2632694|emb|CAB12201.1| (Z99106) glucose 1-dehydrogenase [Bacillus subtilis] Length = 261 Score = 80.8 bits (196), Expect = 2e-14 Identities = 64/258 (24%), Positives = 122/258 (46%), Gaps = 20/258 (7%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIA----SSNPDNIRKAYEKLKEIGEIHYFKADLK 58 + IT A+ G+G +A K+ +V I +P+ +++ E +K GE + D+ Sbjct: 10 VAITGAASGLGKAMAIRFGKEQAKVVINYYSNKQDPNEVKE--EVIKAGGEAVVVQGDVT 67 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYIT 117 ++D+K +++ A + G +D ++ NA G E P +HE DW + ++ + Sbjct: 68 KEEDVKNIVQTAIKEFGTLDIMINNA---GLENPVPSHEMPLKDWDKVIGTNLTGAFLGS 124 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 I+ ++E ++G +I +SS + P P + ++ G+ + + ++ Y KGIR Sbjct: 125 REAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAASKGGIKLMTETLALEYAPKGIRVN 184 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 + G+ +TP E A D + +V P+ G E+ A+ +L S+ Sbjct: 185 NIGPGAINTPINAEKFA----------DPKQKADVESMIPMGYIGEPEEIAAVAAWLASK 234 Query: 238 NAEYMLGSTIVFDGAMTR 255 A Y+ G T+ DG MT+ Sbjct: 235 EASYVTGITLFADGGMTQ 252 >sp|O07399|FABG_MYCAV 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) >gi|2183267|gb|AAC46203.1| (AF002133) ketoacyl-reductase [Mycobacterium avium] Length = 255 Score = 80.8 bits (196), Expect = 2e-14 Identities = 70/259 (27%), Positives = 111/259 (42%), Gaps = 35/259 (13%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIA---SSNPDNIRKAYEKLKEIGEIHYFKADLKS 59 +L+T +RGIG IA+ L + H+V++ S PD + + D+ Sbjct: 26 VLVTGGNRGIGLAIAQRLAAEAHKVAVTHRGSGAPDGLFGV-------------ECDVTD 72 Query: 60 KDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAH--EARYIDWLEAALLHIVAPGYIT 117 D + E E G ++ LV NA + + + E R+ + + A L + Sbjct: 73 NDAVDRAFTEVEEHQGPVEVLVSNA-GISKDAFLIRMTEERFTEVINANL----TGAFRV 127 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 T ++KK G IIY+ S S + + A+AGL+ +A+ ISR G+ A Sbjct: 128 TQRAARSMQKKRFGRIIYIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELSKAGVTAN 187 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 V G DT R +DE + ++ P KR G +E+ + FL SE Sbjct: 188 VVAPGYIDTEMTR------------ALDERIQAGALEFIPAKRVGTAAEVPGAVSFLASE 235 Query: 238 NAEYMLGSTIVFDGAMTRG 256 +A Y+ G+ I DG M G Sbjct: 236 DASYIAGAVIPVDGGMGMG 254 >gb|AAC44307.1| (U59433) 3-ketoacyl-acyl carrier protein reductase [Bacillus subtilis] Length = 246 Score = 80.4 bits (195), Expect = 2e-14 Identities = 68/252 (26%), Positives = 116/252 (45%), Gaps = 17/252 (6%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIA-SSNPDNIRKAYEKLKEIG-EIHYFKADLKSKD 61 ++T ASRGIG +IA L K G V + S N + +++K +G + KAD+ + + Sbjct: 8 IVTGASRGIGRSIALALAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIAVKADVSNPE 67 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 D++ +IKE ID LV NA M + +W + +++ + T + Sbjct: 68 DVQNMIKETLSVFSTIDILVNNAGITRDNLIM--RMKEDEWDDVININLKGV-FNCTKAV 124 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 + K+ G II +SS + P A+AG++ L K ++ + I + Sbjct: 125 TRQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASRNITVNAIAP 184 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEY 241 G T + LA+ ++ E++ + PL R G S++ +++ FL SE A Y Sbjct: 185 GFISTD-MTDKLAKDVQD-----------EMLKQIPLARFGEPSDVSSVVTFLASEGARY 232 Query: 242 MLGSTIVFDGAM 253 M G T+ DG M Sbjct: 233 MTGQTLHIDGGM 244 >pir||H75616 oxidoreductase, short-chain dehydrogenase/reductase family - Deinococcus radiodurans (strain R1) >gi|6460474|gb|AAF12180.1|AE001862_6 (AE001862) oxidoreductase, short-chain dehydrogenase/reductase family [Deinococcus radiodurans] Length = 258 Score = 80.4 bits (195), Expect = 2e-14 Identities = 64/256 (25%), Positives = 116/256 (45%), Gaps = 19/256 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 LIT SRG+G +A+ L + G V + + + + +A L+ +G + H + DL + + Sbjct: 15 LITGGSRGLGLQMAEALGEYGATVVLTARKQNELDEAKAHLEGLGVKAHVYANDLGNFES 74 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQ 122 I LI + + +G ID L+ NA P H + W++ +++ +T ++ Sbjct: 75 IDPLIAQIHQEVGPIDILINNAGATWGAPTAEHP--FDAWMKVMNVNVNGTFLLTQSVLN 132 Query: 123 AWLEKKMRGVIIYLSSASVLE----PMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 + +G II ++S + L+ M P + +T++ +V + ++ KGI + Sbjct: 133 RCMLPAGKGRIINVASVAGLKGNSPQMMPTMAYNTSKGAVVNFTRALASELAPKGITVNS 192 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 + G F T R LA E+ ++ TP+ R G +L L L S+ Sbjct: 193 ICPGYFPTKMTRGTLAAA------------EQAIMSHTPMGRLGTDQDLKGLAVLLSSDA 240 Query: 239 AEYMLGSTIVFDGAMT 254 + YM G I DG +T Sbjct: 241 SAYMTGQNIAVDGGIT 256 >pir||S47054 probable dehydrogenase (EC 1.1.1.-) - Xanthobacter sp >gi|581833|emb|CAA56244.1| (X79863) orf4 [Xanthobacter sp. Py2] Length = 250 Score = 80.0 bits (194), Expect = 3e-14 Identities = 67/260 (25%), Positives = 110/260 (41%), Gaps = 26/260 (10%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYF---------K 54 ++T AS G G IA L +G V+ + E L+E H+ + Sbjct: 6 IVTGASSGNGLAIATRFLARGDRVAALDLSA-------ETLEETARTHWHAYADKVLRVR 58 Query: 55 ADLKSKDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPG 114 AD+ + D+ I E GAID LV NA G ++ + + V Sbjct: 59 ADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGI 118 Query: 115 YITTLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGI 174 ++ + + + GVI+ ++S + L P T++ ++QL K ++ Y G GI Sbjct: 119 FLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGI 178 Query: 175 RAYTVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFL 234 R V G +TP + L + E R +V+ R P K G +++ + FL Sbjct: 179 RCNAVCPGMIETPMTQWRLDQ-PELRD---------QVLARIPQKEIGTAAQVADAVMFL 228 Query: 235 LSENAEYMLGSTIVFDGAMT 254 E+A Y+ G+ +V DGA T Sbjct: 229 AGEDATYVNGAALVMDGAYT 248 >emb|CAC11337.1| (AL445063) probable glucose 1-dehydrogenase [Thermoplasma acidophilum] Length = 268 Score = 80.0 bits (194), Expect = 3e-14 Identities = 63/257 (24%), Positives = 115/257 (44%), Gaps = 24/257 (9%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIA-SSNPDNIRKAYEKLKEIGEIHY-FKADLKSKD 61 L+T +S G+G IAK + + G +V++ S D +++K G F D+ K+ Sbjct: 19 LVTGSSSGLGAAIAKYMARAGAKVAVHYRSGKDRADAIVDEIKNDGGFAMAFYGDVSKKE 78 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 D++ L E +G +D LV NA G + + DW + ++++ P Y + Sbjct: 79 DVQKLFSEIDSKLGTVDILVNNAGIDGKRELVGEDDPD-DWEKVIEVNLMGPYYCAREAV 137 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 + KK GVII ++S P +A+AGL K +++ IR + Sbjct: 138 KRMKPKKS-GVIINITSVHEYVPWSGYTAYSSAKAGLSMFTKALAQELSDYNIRVVAIAP 196 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWE-----REVIDRTPLKRTGRWSELGALIDFLLS 236 G+ TP ++ +W ++++++ + R G ++G FL S Sbjct: 197 GAIKTPINKD---------------VWGNPESLKDLLNKIAMPRLGEVDDIGQAAVFLAS 241 Query: 237 ENAEYMLGSTIVFDGAM 253 + A Y+ G+T++ DG M Sbjct: 242 DLASYITGTTLLVDGGM 258 >emb|CAA05517.1| (AJ002527) glucitol-6-phosphate dehydrogenase [Clostridium beijerinckii] Length = 271 Score = 80.0 bits (194), Expect = 3e-14 Identities = 71/263 (26%), Positives = 120/263 (44%), Gaps = 15/263 (5%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDDI 63 ++T + GIG +A+E L G V + NP+ E G + Y ++ +D + Sbjct: 14 IVTGGASGIGKAVAQEFLNNGANVVVCDMNPNKP----EFDDHNGHMEYIVTNVADRDSV 69 Query: 64 KLLIKEAWEAMGAIDALVWNA----PNVGC---EPCMAHEARYIDWLEAALLHIVAPGYI 116 + +I++A E G ID +V NA P + EP E W + +++ ++ Sbjct: 70 EKMIEKAKEITGTIDIIVNNAGINIPRLLVDKKEPKGKFELDENVWDKVMNVNVKGV-FL 128 Query: 117 TTLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRA 176 + + + +GVII +SS S LE + ++ + L + ++ G GIR Sbjct: 129 CAQVAAREMASQGKGVIINMSSESGLEGSEGQSVYAASKNAVNSLTRSWAKELGKLGIRV 188 Query: 177 YTVLLGSFDTPGAR--ENLARIAEERGVTMDEIWER-EVIDRTPLKRTGRWSELGALIDF 233 V G + G R E +A RG+T++E+ TPL R+G+ SE+ L+ + Sbjct: 189 IGVAPGILEATGLRTLEYETALAYTRGITVEELRAGYSKTSTTPLGRSGKLSEVADLVCY 248 Query: 234 LLSENAEYMLGSTIVFDGAMTRG 256 L S+ A Y+ G T G TRG Sbjct: 249 LASDRASYIHGVTYNIAGGKTRG 271 >gb|AAD37452.1| (AF074603) putative ketoacyl reductase; NonM [Streptomyces griseus subsp. griseus] Length = 533 Score = 79.6 bits (193), Expect = 4e-14 Identities = 66/257 (25%), Positives = 115/257 (44%), Gaps = 17/257 (6%) Query: 2 RILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHY-FKADLKSK 60 ++L+ AS GIG A L +G +V +A+ + + +++ G + + DL Sbjct: 264 KVLVAGASSGIGRAAALHLAGRGADVILAARRTQALEEVAAEIEARGRQAWTLRCDLSDA 323 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL 120 +D L + AW+A + AL++ A ++G A L VA +T L Sbjct: 324 EDAASLGERAWKAADGVTALLYAAGHLGFSAVGGDPASAARTFAVNLHSFVA---VTEYL 380 Query: 121 IQAWLEKKMRGVIIYLSS-ASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 W +++M G ++ +SS +S L P+ L ++A + Q + ++ + G GIRA V Sbjct: 381 AARWRDERMPGAVVGVSSVSSTLSPVAGLEYYGASKAAMAQYIRCLAVSVGRHGIRANCV 440 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G +TP + + G W I R P R G E+ A++ +LLS +A Sbjct: 441 APGIIETP--------MGDAAGPDHRRGW----ISRIPAGRVGDPHEVAAVLGYLLSGSA 488 Query: 240 EYMLGSTIVFDGAMTRG 256 + G+ + DG G Sbjct: 489 SRVTGAVLRADGGFGLG 505 >pir||D72377 oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima (strain MSB8) >gi|4980948|gb|AAD35526.1|AE001722_10 (AE001722) oxidoreductase, short chain dehydrogenase/reductase family [Thermotoga maritima] Length = 255 Score = 79.2 bits (192), Expect = 5e-14 Identities = 72/254 (28%), Positives = 116/254 (45%), Gaps = 16/254 (6%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI--GEIHYFKADLKSKD 61 L+T SRG+GF IA+ L + G V +AS N + +A +KL E E F+ D+ + + Sbjct: 13 LVTGGSRGLGFGIAQGLAEAGCSVVVASRNLEEASEAAQKLTEKYGVETMAFRCDVSNYE 72 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 ++K L++ E G +D +V NA + A E ++ + +++ Y+ Sbjct: 73 EVKKLLEAVKEKFGKLDTVV-NAAGIN-RRHPAEEFPLDEFRQVIEVNLFGTYYVCREAF 130 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTA-RAGLVQLAKGISRTYGGKGIRAYTVL 180 + L + II + S +V E P I A A + G+ L K +++ +G GIR + Sbjct: 131 -SLLRESDNPSIINIGSLTVEEVTMPNISAYAASKGGVASLTKALAKEWGRYGIRVNVIA 189 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 G + R V D ++ R PL RTG +L + FL SE A+ Sbjct: 190 PGWY----------RTKMTEAVFSDPEKLDYMLKRIPLGRTGVPEDLKGVAVFLASEEAK 239 Query: 241 YMLGSTIVFDGAMT 254 Y+ G I DG T Sbjct: 240 YVTGQIIFVDGGWT 253 >sp|P10528|DHGA_BACME GLUCOSE 1-DEHYDROGENASE A >gi|80114|pir||S00812 glucose 1-dehydrogenase (EC 1.1.1.47) A - Bacillus megaterium >gi|39635|emb|CAA30931.1| (X12370) glucose dehydrogenase A (AA 1 - 261) [Bacillus megaterium] Length = 261 Score = 78.8 bits (191), Expect = 6e-14 Identities = 64/258 (24%), Positives = 119/258 (45%), Gaps = 20/258 (7%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI----GEIHYFKADLK 58 ++IT S G+G +A ++ +V I N N +A + KE+ G+ + D+ Sbjct: 10 VVITGGSTGLGRAMAVRFGQEEAKVVINYYN--NEEEALDAKKEVEEAGGQAIIVQGDVT 67 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYIT 117 ++D+ L++ A + G +D ++ NA G E P +HE +W + ++ + Sbjct: 68 KEEDVVNLVQTAIKEFGTLDVMINNA---GVENPVPSHELSLDNWNKVIDTNLTGAFLGS 124 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 I+ ++E ++G +I +SS + P P + ++ G+ + + ++ Y KGIR Sbjct: 125 REAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 184 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 + G+ +TP E A D +V P+ G+ E+ A+ FL S Sbjct: 185 NIGPGAMNTPINAEKFA----------DPEQRADVESMIPMGYIGKPEEVAAVAAFLASS 234 Query: 238 NAEYMLGSTIVFDGAMTR 255 A Y+ G T+ DG MT+ Sbjct: 235 QASYVTGITLFADGGMTK 252 >sp|P39482|DHG1_BACME GLUCOSE 1-DEHYDROGENASE I (GLCDH-I) >gi|80112|pir||JS0385 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium >gi|216268|dbj|BAA14099.1| (D90043) glucose dehydrogenase [Bacillus megaterium] >gi|228657|prf||1808263C glucose dehydrogenase I [Bacillus megaterium] Length = 261 Score = 78.8 bits (191), Expect = 6e-14 Identities = 63/256 (24%), Positives = 116/256 (44%), Gaps = 16/256 (6%) Query: 3 ILITAASRGIGFNIA-KELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSK 60 ++IT +S G+G +A + +K V S + E++K++G E K D+ + Sbjct: 10 VVITGSSTGLGKAMAIRFATEKAKVVVNYRSKEEEANSVLEEIKKVGGEAIAVKGDVTVE 69 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYITTL 119 D+ L++ + + G +D ++ NA G E P +HE DW + ++ + Sbjct: 70 SDVINLVQSSIKEFGKLDVMINNA---GMENPVSSHEMSLSDWNKVIDTNLTGAFLGSRE 126 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 I+ ++E ++G +I +SS P P + ++ G+ + + ++ Y KGIR + Sbjct: 127 AIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNI 186 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G+ +TP E A D +V P+ G E+ A+ +L S A Sbjct: 187 GPGAINTPINAEKFA----------DPEQRADVESMIPMGYIGEPEEIAAVAAWLASSEA 236 Query: 240 EYMLGSTIVFDGAMTR 255 Y+ G T+ DG MT+ Sbjct: 237 SYVTGITLFADGGMTQ 252 >pir||G75333 3-oxoacyl-acyl carrier protein reductase - Deinococcus radiodurans (strain R1) >gi|6459730|gb|AAF11496.1|AE002033_4 (AE002033) 3-oxoacyl-acyl carrier protein reductase [Deinococcus radiodurans] Length = 254 Score = 78.4 bits (190), Expect = 8e-14 Identities = 68/254 (26%), Positives = 116/254 (44%), Gaps = 21/254 (8%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI----GEIHYFKADLKS 59 L+T +SRG+G +A L + G V++ + +A + +I G F ADL Sbjct: 15 LVTGSSRGLGRAMALRLAQDGFTVAVHYGRGE--AEAQQVAADIRAAGGAAQVFGADLSQ 72 Query: 60 KDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTL 119 + L+++ A+G +D LV NA +A + DW +A L ++ + Sbjct: 73 PANAGTLVEDVIAALGRLDVLVNNAGIT--RDGLAIRMKDEDW-DAVLQTNLSSAFAACR 129 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 + K G I+ +SS L P ++AGL+ L + +++ YGG+GI + Sbjct: 130 AALKHMMKNRSGRIVNVSSVVALAGNPGQANYVASKAGLIGLTRALAKEYGGRGITVNAI 189 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G ++ + A++ E+ +++ PL R G+ E+ AL+ FL SE A Sbjct: 190 APGFIES----DMTAKLPEDT--------KKQYQANIPLARFGQPEEVAALVAFLASEGA 237 Query: 240 EYMLGSTIVFDGAM 253 Y+ G TI DG M Sbjct: 238 GYITGQTIGVDGGM 251 >emb|CAC11810.1| (AL445065) polyketide synthase chain 7 related protein [Thermoplasma acidophilum] Length = 258 Score = 78.4 bits (190), Expect = 8e-14 Identities = 73/251 (29%), Positives = 116/251 (46%), Gaps = 12/251 (4%) Query: 4 LITAASRGIGFNIAKELLKKGHEV-SIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDD 62 ++T A +GIG IA LL G EV I + PD+ + G H + S DD Sbjct: 16 VVTGAFQGIGKAIADALLDAGAEVYGIDKAFPDHG-------VDEGRFHGLHGSVDSLDD 68 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQ 122 I L E G +D LV NA + ++ D+ +++ +T +Q Sbjct: 69 IASLRDRVAETSGRLDFLVNNAGIYFYKKI--EDSTEDDYERITSVNLKGYFLMTREFLQ 126 Query: 123 AWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLG 182 L K I+ ++S S P L + G++ L + +S G GIR +V G Sbjct: 127 L-LRKSDYPSIVNIASVSGQRPEAGHPLYSMTKGGILALTRALSADLGMLGIRVNSVSPG 185 Query: 183 SFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYM 242 + TP E++ A +RG+ DE+ ER+ + L R G +E+ +++ FLLS+ A Y+ Sbjct: 186 NIKTPMNDEDILDQARKRGLDPDEV-ERQYAAESVLGRRGEAAEVASVVLFLLSKGASYI 244 Query: 243 LGSTIVFDGAM 253 G+ IV DG + Sbjct: 245 NGADIVVDGGL 255 >dbj|BAB18775.1| (AB045131) NADPH-dependent retinol dehydrogenase/reductase [Homo sapiens] Length = 260 Score = 78.4 bits (190), Expect = 8e-14 Identities = 64/252 (25%), Positives = 116/252 (45%), Gaps = 19/252 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 L+TA++ GIGF IA+ L + G V ++S N+ +A L+ G + + +D Sbjct: 18 LVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAED 77 Query: 63 IKLLIKEAWEAMGAIDALVWNA---PNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTL 119 + L+ A + G ID LV NA P G + E W + +++ AP +T Sbjct: 78 RERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEV----WDKTLDINVKAPALMTKA 133 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 ++ +EK+ G ++ +SS + P P + ++ L+ L K ++ + IR + Sbjct: 134 VVPE-MEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 192 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G L + + R + MD+ E + + ++R G + ++ FL SE+A Sbjct: 193 APG----------LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDA 242 Query: 240 EYMLGSTIVFDG 251 Y+ G T+V G Sbjct: 243 SYITGETVVVGG 254 >sp|P28643|FABG_CUPLA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE PRECURSOR (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) >gi|1084385|pir||S22450 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) precursor, NADPH-dependent [validated] - Cuphea lanceolata >gi|18046|emb|CAA45866.1| (X64566) 3-oxoacyl-[acyl-carrier protein] reductase [Cuphea lanceolata] >gi|228929|prf||1814446A beta ketoacyl-ACP reductase [Cuphea lanceolata] Length = 320 Score = 78.0 bits (189), Expect = 1e-13 Identities = 67/257 (26%), Positives = 117/257 (45%), Gaps = 22/257 (8%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI----GEIHYFKADLK 58 +++T ASRGIG IA L K G +V + + ++A E KEI G+ F D+ Sbjct: 80 VIVTGASRGIGKAIALSLGKAGCKVLVNYARSS--KEAEEVSKEIEAFGGQALTFGGDVS 137 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITT 118 ++D++ +IK A +A G +D LV NA + + W E L++ ++ T Sbjct: 138 KEEDVEAMIKTAVDAWGTVDILVNNAGIT--RDGLLMRMKKSQWQEVIDLNLTGV-FLCT 194 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 + KK +G II ++S L A+AG++ K ++R Y + I Sbjct: 195 QAAAKIMMKKKKGRIINIASVVGLVGNAGQANYSAAKAGVIGFTKTVAREYASRNINVNA 254 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFL-LSE 237 V G I+ + + + +++++ PL R G+ E+ L++FL ++ Sbjct: 255 VAPGF------------ISSDMTSKLGDDINKKILETIPLGRYGQPEEVAGLVEFLAINP 302 Query: 238 NAEYMLGSTIVFDGAMT 254 + Y+ G DG MT Sbjct: 303 ASSYVTGQVFTIDGGMT 319 >gi|10337605 peroxisomal short-chain alcohol dehydrogenase [Homo sapiens] >gi|4105190|gb|AAD02292.1| (AF044127) peroxisomal short-chain alcohol dehydrogenase [Homo sapiens] Length = 260 Score = 78.0 bits (189), Expect = 1e-13 Identities = 64/252 (25%), Positives = 116/252 (45%), Gaps = 19/252 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 L+TA++ GIGF IA+ L + G V ++S N+ +A L+ G + + +D Sbjct: 18 LVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAED 77 Query: 63 IKLLIKEAWEAMGAIDALVWNA---PNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTL 119 + L+ A + G ID LV NA P G + E W + +++ AP +T Sbjct: 78 RERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEV----WDKTLDINVKAPALMTKA 133 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 ++ +EK+ G ++ +SS + P P + ++ L+ L K ++ + IR + Sbjct: 134 VVPE-MEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 192 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G L + + R + MD+ E + + ++R G + ++ FL SE+A Sbjct: 193 APG----------LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDA 242 Query: 240 EYMLGSTIVFDG 251 Y+ G T+V G Sbjct: 243 SYITGETVVVGG 254 >gb|AAF50801.1| (AE003567) CG10672 gene product [Drosophila melanogaster] Length = 317 Score = 78.0 bits (189), Expect = 1e-13 Identities = 61/253 (24%), Positives = 112/253 (44%), Gaps = 15/253 (5%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 ++TA++ GIGF IAK L + G V I+S N+ A +L+++ +H K + +D Sbjct: 75 VVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVHGLKCHVSEPED 134 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHI-VAPGYITTLLI 121 K L +E G ++ LV NA P + + + + + V Y+ Sbjct: 135 RKQLFEETISKFGKLNILVSNAAT---NPAVGGVLECDEKVWDKIFDVNVKSSYLLAKEA 191 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 L ++ I+++SS + + L ++ L+ L K ++ +GIR + Sbjct: 192 LPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAP 251 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEY 241 G + R + + +E + + P+ R G E+ ++ FL+SE+A Y Sbjct: 252 G----------VIRTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGY 301 Query: 242 MLGSTIVFDGAMT 254 + G +IV G MT Sbjct: 302 ITGESIVAGGGMT 314 >pir||S36090 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus subtilis >gi|142955|gb|AAA22463.1| (M12276) glucose dehydrogenase (EC 1.1.1.47) [Bacillus subtilis] Length = 260 Score = 77.6 bits (188), Expect = 1e-13 Identities = 64/258 (24%), Positives = 121/258 (46%), Gaps = 21/258 (8%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIA----SSNPDNIRKAYEKLKEIGEIHYFKADLK 58 + IT A+ G+G +A K+ +V I +P+ +++ E +K GE + D+ Sbjct: 10 VAITGAASGLGKAMAIRFGKEQAKVVINYYSNKQDPNEVKE--EVIKAGGEAVVVQGDVT 67 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYIT 117 ++D+K +++ A + G +D ++ NA G E P +HE DW + ++ + Sbjct: 68 KEEDVKNIVQTAIKEFGTLDIMINNA---GLENPVPSHEMPLKDWDKVIGTNLTGAFLGS 124 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 I+ ++E ++G +I +SS P P + ++ G+ + + ++ Y KGIR Sbjct: 125 REAIKYFVENDIKGNVINMSSVHAF-PWPLFVHYAASKGGIKLMTETLALEYAPKGIRVN 183 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 + G+ +TP E A D + +V P+ G E+ A+ +L S+ Sbjct: 184 NIGPGAINTPINAEKFA----------DPKQKADVESMIPMGYIGEPEEIAAVAAWLASK 233 Query: 238 NAEYMLGSTIVFDGAMTR 255 A Y+ G T+ DG MT+ Sbjct: 234 EASYVTGITLFADGGMTQ 251 >pir||T22676 hypothetical protein F54F3.4 - Caenorhabditis elegans >gi|3877595|emb|CAB01974.1| (Z79696) predicted using Genefinder~Similarity to Human HEP27 protein (TR:G1079566), contains similarity to Pfam domain: PF00106 (short chain dehydrogenase), Score=187.6, E-value=6.3e-53, N=1; PF00678 (Short chain dehydrogenase/reductase C-terminus), S> >gi|3879853|emb|CAB04734.1| (Z81592) predicted using Genefinder~Similarity to Human HEP27 protein (TR:G1079566), contains similarity to Pfam domain: PF00106 (short chain dehydrogenase), Score=187.6, E-value=6.3e-53, N=1; PF00678 (Short chain dehydrogenase/reductase C-terminus), S> Length = 260 Score = 77.6 bits (188), Expect = 1e-13 Identities = 66/253 (26%), Positives = 111/253 (43%), Gaps = 13/253 (5%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG--EIHYFKADLKSKD 61 ++TAA++GIG IA+ LL +G V I S N N+ +A E LK G ++ + S D Sbjct: 14 IVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIASTD 73 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHI-VAPGYITTLL 120 D K L+ + G I+ LV N G P H D + L + V G+ T L Sbjct: 74 DQKKLVDFTLQKFGKINILV---NNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKL 130 Query: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 + + K+ G II+ +S S + P + + LV L + ++ IR + Sbjct: 131 VHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIA 190 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 G T ++++ + G ++ E I L R G + + +L S+++ Sbjct: 191 PGVIKT-----KMSQVLWDGGEDAEK--ELTDIQEIALGRLGVPDDCAGTVAYLASDDSS 243 Query: 241 YMLGSTIVFDGAM 253 Y+ G I+ G + Sbjct: 244 YITGEMIIIAGGV 256 >sp|P42317|YXJF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PEPT-KATB INTERGENIC REGION >gi|7431062|pir||D70079 gluconate 5-dehydrogenase homolog yxjF - Bacillus subtilis >gi|666004|dbj|BAA11707.1| (D83026) homologous to many ketoreductases and steroid dehydrogenases; hypothetical [Bacillus subtilis] >gi|2636432|emb|CAB15923.1| (Z99123) similar to gluconate 5-dehydrogenase [Bacillus subtilis] >gi|2636443|emb|CAB15933.1| (Z99124) similar to gluconate 5-dehydrogenase [Bacillus subtilis] Length = 257 Score = 77.3 bits (187), Expect = 2e-13 Identities = 65/252 (25%), Positives = 110/252 (42%), Gaps = 4/252 (1%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 L+T A+ GI F IA+E ++G V ++ P+ KA KL E G + D+ + Sbjct: 7 LVTGAAGGIRFEIAREFAREGASVIVSDLRPEACEKAASKLAEEGFDAAAIPYDVTKEAQ 66 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQ 122 + + + G +D LV NA G + E D E + ++ +I + Sbjct: 67 VADTVNVIQKQYGRLDILVNNA---GIQHVAPIEEFPTDTFEQLIKVMLTAPFIAMKHVF 123 Query: 123 AWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLG 182 ++K+ G II ++S + L ++A+ G++ L K + GI + G Sbjct: 124 PIMKKQQFGRIINIASVNGLVGFAGKSAYNSAKHGVIGLTKVGALEGAPHGITVNALCPG 183 Query: 183 SFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYM 242 DT R L+ +++ R V D + E+ + P KR E+ FL SE A+ + Sbjct: 184 YVDTQLVRNQLSDLSKTRNVPYDSVLEQVIFPLVPQKRLLSVKEIADYAVFLASEKAKGV 243 Query: 243 LGSTIVFDGAMT 254 G +V DG T Sbjct: 244 TGQAVVLDGGYT 255 >pir||S01227 glucose 1-dehydrogenase (EC 1.1.1.47) B - Bacillus megaterium Length = 263 Score = 76.9 bits (186), Expect = 2e-13 Identities = 63/258 (24%), Positives = 121/258 (46%), Gaps = 18/258 (6%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAY--EKLKEIG-EIHYFKADLKS 59 ++IT +S G+G ++A + +V + + ++ + E++K++G E K D+ Sbjct: 10 VVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEEIKKVGGEAIAVKGDVTV 69 Query: 60 KDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYITT 118 + D+ L++ A + G +D ++ NA G E P +HE DW + ++ + Sbjct: 70 ESDVINLVQSAIKEFGKLDVMINNA---GMENPVSSHEMSLSDWNKVIDTNLTGAFLGSR 126 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLE-PMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 I+ ++E ++G++I +SS + P P + ++ G+ + + ++ Y KGIR Sbjct: 127 EAIKYFVENDIKGIVINMSSVHEWKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 186 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 + G+ +TP E A D +V P+ G EL A+ +L S Sbjct: 187 NIGPGAINTPINAEKFA----------DPEQRADVESMIPMGYIGEPEELAAVAAWLASS 236 Query: 238 NAEYMLGSTIVFDGAMTR 255 A Y+ G T+ DG MT+ Sbjct: 237 EASYVTGITLFADGGMTQ 254 >dbj|BAA91953.1| (AK001870) unnamed protein product [Homo sapiens] Length = 278 Score = 76.9 bits (186), Expect = 2e-13 Identities = 64/252 (25%), Positives = 115/252 (45%), Gaps = 19/252 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 L TA++ GIGF IA+ L + G V ++S N+ +A L+ G + + +D Sbjct: 36 LATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAED 95 Query: 63 IKLLIKEAWEAMGAIDALVWNA---PNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTL 119 + L+ A + G ID LV NA P G + E W + +++ AP +T Sbjct: 96 RERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEV----WDKTLDINVKAPALMTKA 151 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 ++ +EK+ G ++ +SS + P P + ++ L+ L K ++ + IR + Sbjct: 152 VVPE-MEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G L + + R + MD+ E + + ++R G + ++ FL SE+A Sbjct: 211 APG----------LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDA 260 Query: 240 EYMLGSTIVFDG 251 Y+ G T+V G Sbjct: 261 SYITGETVVVGG 272 >sp|Q9WYG0|Y325_THEMA HYPOTHETICAL OXIDOREDUCTASE TM0325 >gi|7431047|pir||G72389 oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima (strain MSB8) >gi|4980826|gb|AAD35412.1|AE001714_3 (AE001714) oxidoreductase, short chain dehydrogenase/reductase family [Thermotoga maritima] Length = 251 Score = 76.5 bits (185), Expect = 3e-13 Identities = 66/254 (25%), Positives = 119/254 (45%), Gaps = 14/254 (5%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKD 61 +LIT A GIG A ++G +V+I + + ++ E +K +G E + D+ Sbjct: 8 VLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIFGDVAK-- 65 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPC-MAHEARYIDWLEAALLHIVAPGYITTLL 120 D + ++K+ E G +D LV NA G P E D+ + +++ P ++ Sbjct: 66 DAEQIVKKTVETFGRLDILVNNA---GIVPYGNIEETSEEDFDKTMAVNVKGPFLLSKYA 122 Query: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 ++ ++K+ GVI+ +SS + L +P + ++A L+ L + ++ Y GIR V Sbjct: 123 VEQ-MKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVNAVC 181 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 PG ++ +A + E +++ R P+KR G+ E+ I F + A Sbjct: 182 ------PGTTQSEGLMARVKASPNPEELLKKMTSRIPMKRLGKEEEIAFAILFAACDEAG 235 Query: 241 YMLGSTIVFDGAMT 254 +M GS I DG T Sbjct: 236 FMTGSIINIDGGST 249 >gb|AAD38447.1|AF099742_1 (AF099742) putative short-chain dehydrogenase/reductase [Rattus norvegicus] >gi|6491860|gb|AAF14047.1|AF021854_1 (AF021854) peroxisomal 2,4-dienoyl CoA reductase px-2,4-DCR#1 [Rattus norvegicus] Length = 303 Score = 76.5 bits (185), Expect = 3e-13 Identities = 65/257 (25%), Positives = 114/257 (44%), Gaps = 24/257 (9%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLK------EIGEIHYFKADL 57 ++T + GIG I++ELL G V IAS D + A ++L+ ++ + ++ Sbjct: 22 VVTGGATGIGKAISRELLHLGCNVVIASRKLDRLTAAVDELRASQPPSSSTQVTAIQCNI 81 Query: 58 KSKDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYIT 117 + ++++ L+K G I+ LV NA P A + W ++ Y+ Sbjct: 82 RKEEEVNNLVKSTLAKYGKINFLVNNAGGQFMAP--AEDITAKGWQAVIETNLTGTFYMC 139 Query: 118 TLLIQAWLEK---KMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGI 174 + +W++ + +I+ L++ P + ARAG+ L K ++ T+ G+ Sbjct: 140 KAVYNSWMKDHGGSIVNIIVLLNNG-----FPTAAHSGAARAGVYNLTKTMALTWASSGV 194 Query: 175 RAYTVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFL 234 R V G+ + A +N E G TM E+ + P KR G E+ L+ FL Sbjct: 195 RINCVAPGTIYSQTAVDNYG----ELGQTMFEM----AFENIPAKRVGLPEEISPLVCFL 246 Query: 235 LSENAEYMLGSTIVFDG 251 LS A ++ G I DG Sbjct: 247 LSPAASFITGQLINVDG 263 >gb|AAD49430.1|AF173833_1 (AF173833) 7-alpha-hydroxysteroid dehydrogenase [Bacteroides fragilis] Length = 259 Score = 75.7 bits (183), Expect = 5e-13 Identities = 74/257 (28%), Positives = 118/257 (45%), Gaps = 20/257 (7%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGE----IHYFKADLK 58 I+IT A+ GIG + + ++ +G +V IA + + + +L G +++ +LK Sbjct: 9 IIITGAAGGIGASTTRRIVSEGGKVVIADYSREKADQFAAELSNSGADVRPVYFSATELK 68 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAAL-LHIVAPGYIT 117 S K LI + G ID LV N E +D+ + A L++ Y++ Sbjct: 69 S---CKELITFTMKEYGQIDVLVNNVGGTNPRRDTNIETLDMDYFDEAFHLNLSCTMYLS 125 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 L+I + + G I+ ++S S P+ L ++AG++ L K I+ G K IR Sbjct: 126 QLVIPI-MSTQGGGNIVNVASISGSRPIWNGTLYGASKAGVINLTKYIATQTGKKNIRCN 184 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 V G TP A NL E R + + + TP G ++ A I FL SE Sbjct: 185 AVAPGLILTPAALNNLNE--EVRKIFLGQC-------ATPY--LGEPQDVAATIAFLASE 233 Query: 238 NAEYMLGSTIVFDGAMT 254 +A Y+ G TIV DG +T Sbjct: 234 DARYITGQTIVVDGGLT 250 >emb|CAB59447.1| (AL132644) putative oxidoreductase [Streptomyces coelicolor A3(2)] Length = 251 Score = 75.7 bits (183), Expect = 5e-13 Identities = 74/254 (29%), Positives = 110/254 (43%), Gaps = 15/254 (5%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDDI 63 ++T A+RG+G A+EL+ G +V + + ++ +A L + AD + Sbjct: 11 VVTGATRGLGNAAARELVADGAKVVVTGRDEKSVAQAAAALGP--DAVGVAADNADPEAA 68 Query: 64 KLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQA 123 LI A E G D ++ + G P + W A V G + L A Sbjct: 69 GRLIATARERFGRFDGVLISVG--GPPPGFVADTTDEQWQSA--FESVFLGAVR-LARAA 123 Query: 124 WLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLGS 183 E GVI ++ S SV EP+P L +++ R GL AK ++ G +GIR +L G Sbjct: 124 AAELADGGVIGFVLSGSVHEPIPGLTISNGLRPGLAGFAKSLADELGPRGIRVVGLLPGR 183 Query: 184 FDTPGARENLARIAEERGVTMD-EIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYM 242 DT R+ E G++ D E R PL+R G E G FLLS A Y+ Sbjct: 184 VDTD-------RVRELDGLSADPEATRAAAESRIPLRRYGAPEEFGRASAFLLSPAASYI 236 Query: 243 LGSTIVFDGAMTRG 256 G + DG + G Sbjct: 237 TGVMLPVDGGVRHG 250 >sp|P71534|FABG_MYCSM 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) >gi|1561753|gb|AAC69638.1| (U66800) 3-ketoacyl reductase [Mycobacterium smegmatis] Length = 255 Score = 75.3 bits (182), Expect = 7e-13 Identities = 68/259 (26%), Positives = 109/259 (41%), Gaps = 35/259 (13%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIA---SSNPDNIRKAYEKLKEIGEIHYFKADLKS 59 +L+T +RGIG IA+ L GH+V++ S PD ++ + D+ Sbjct: 26 VLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPD-------------DLFGVQCDVTD 72 Query: 60 KDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAH--EARYIDWLEAALLHIVAPGYIT 117 + KE E G ++ LV NA + + + E R+ + + L + Sbjct: 73 SAGVDRAFKEVEEHQGPVEVLVANA-GISKDAFLMRMTEERFEEVINTNL----TGAFRC 127 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 +++K G II++ S S + + A+AGL+ +A+ ISR G+ A Sbjct: 128 AQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELDKAGVTAN 187 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 + G DT R +DE + ID P KR G E+ + FL SE Sbjct: 188 VLPPGYIDTEMTR------------ALDERIQGGAIDFIPDKRVGTVEEVAGAVSFLASE 235 Query: 238 NAEYMLGSTIVFDGAMTRG 256 +A Y+ G+ I DG M G Sbjct: 236 DASYIAGAVIPVDGGMGMG 254 >sp|P39640|YWFD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PTA-ROCC INTERGENIC REGION >gi|629089|pir||S39737 glucose 1-dehydrogenase homolog ywfD - Bacillus subtilis >gi|414006|emb|CAA51638.1| (X73124) ipa-82d [Bacillus subtilis] >gi|2636308|emb|CAB15799.1| (Z99123) alternate gene name: ipa-82d~similar to glucose 1-dehydrogenase [Bacillus subtilis] Length = 255 Score = 75.3 bits (182), Expect = 7e-13 Identities = 64/253 (25%), Positives = 114/253 (44%), Gaps = 10/253 (3%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIR-KAYEKLKEIGEIHYFKADLKSKD 61 +LIT + GIG+ + L G + ++ ++ D + +A + + +H+ + D+ + Sbjct: 10 VLITGGASGIGYAAVQAFL--GQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEA 67 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 + ++ A G +D L+ NA P HE DW + +++ ++ + Sbjct: 68 ACQHAVESAVHTFGGLDVLINNAGIEIVAPI--HEMELSDWNKVLQVNLTGMFLMSKHAL 125 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 + L +G II S L P + + ++ G++QL K ++ Y IR V Sbjct: 126 KHMLAAG-KGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCP 184 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEY 241 G DTP N E T++EI ++E PL R G+ E+ ++ FL S+ + Y Sbjct: 185 GIIDTP---LNEKSFLENNEGTLEEI-KKEKAKVNPLLRLGKPEEIANVMLFLASDLSSY 240 Query: 242 MLGSTIVFDGAMT 254 M GS I DG T Sbjct: 241 MTGSAITADGGYT 253 >gb|AAC38801.1| (AF030176) putative short-chain dehydrogenase/reductase [Rhodococcus opacus] Length = 269 Score = 75.3 bits (182), Expect = 7e-13 Identities = 69/262 (26%), Positives = 118/262 (44%), Gaps = 14/262 (5%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKE---IGEIHYFKADLKSK 60 L+T SRG+GF+IA+ LL++G +V+I + + ++ A +L + AD+ Sbjct: 13 LVTGGSRGLGFSIAQALLERGAKVAIIARDDAAVKAAAGRLDSGAGAQNVLPIVADVADS 72 Query: 61 DDIKLLIKEAWEAMGAIDALVWNA-PNVGCEPCM-AHEARYIDWLEAALLHIVAPGYITT 118 D I + + E G +D +V NA P + P A E + LL + + Sbjct: 73 DSIHEALAQVHEWQGRLDIVVNNAGPQLAPSPVTDADENVLTSAFDTKLLGFLR----VS 128 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 +L + G I+ ++ A+ P+P + A +V L ++ K IR Sbjct: 129 KAALPFLSQDGTGSIVNVAGATAHVPIPNTGVTGIVNASVVALTSFLATEAAAKNIRVNA 188 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRW---SELGALIDFLL 235 + G T G A+++ T DEI R + + R GRW +E+GA FL Sbjct: 189 ISPGMTKTEGWLAKNDAAAQQQDKTADEI--RAGVVQGLGIRLGRWAEPAEIGAAAAFLA 246 Query: 236 SENAEYMLGSTIVFDGAMTRGV 257 S++A Y+ G + DG +++ V Sbjct: 247 SDDASYITGQVLRVDGGLSKPV 268 >dbj|BAB18777.1| (AB045133) NADPH-dependent retinol dehydrogenase/reductase [Oryctolagus cuniculus] Length = 260 Score = 75.3 bits (182), Expect = 7e-13 Identities = 62/252 (24%), Positives = 114/252 (44%), Gaps = 19/252 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 ++TA++ GIG IA+ L + G V I+S N+ +A L+ G + + +D Sbjct: 18 IVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTGTVCHVGKAED 77 Query: 63 IKLLIKEAWEAMGAIDALVWNA---PNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTL 119 + L+ A G ID LV NA P G + E W + +++ A +T Sbjct: 78 RERLVATALNLHGGIDILVSNAAVNPFFGKLMDVTEEV----WDKILDINVKAMALMTKA 133 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 ++ +EK+ G ++ ++S + P L + ++ LV L K ++ + IR + Sbjct: 134 VVPE-MEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIRVNCL 192 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G L + + + + D+ E +I + ++R G+ E ++ FL SE+A Sbjct: 193 APG----------LIKTSFSKALWEDKAQEENIIQKLRIRRLGKPEECAGIVSFLCSEDA 242 Query: 240 EYMLGSTIVFDG 251 Y+ G T+V G Sbjct: 243 SYITGETVVVAG 254 >gi|11433956 peroxisomal short-chain alcohol dehydrogenase [Homo sapiens] Length = 278 Score = 74.9 bits (181), Expect = 9e-13 Identities = 63/252 (25%), Positives = 115/252 (45%), Gaps = 19/252 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 L+TA++ GIGF IA+ L + V ++S N+ +A L+ G + + +D Sbjct: 36 LVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAED 95 Query: 63 IKLLIKEAWEAMGAIDALVWNA---PNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTL 119 + L+ A + G ID LV NA P G + E W + +++ AP +T Sbjct: 96 RERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEV----WDKTLDINVKAPALMTKA 151 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 ++ +EK+ G ++ +SS + P P + ++ L+ L K ++ + IR + Sbjct: 152 VVPE-MEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G L + + R + MD+ E + + ++R G + ++ FL SE+A Sbjct: 211 APG----------LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDA 260 Query: 240 EYMLGSTIVFDG 251 Y+ G T+V G Sbjct: 261 SYITGETVVVGG 272 >sp|P57432|FABG_BUCAI 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) >gi|10039021|dbj|BAB13055.1| (AP001119) 3-oxoacyl-[acyl-carrier protein] reductase [Buchnera sp. APS] Length = 244 Score = 74.1 bits (179), Expect = 2e-12 Identities = 63/249 (25%), Positives = 117/249 (46%), Gaps = 17/249 (6%) Query: 5 ITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDDIK 64 IT A++GIG IAK+L+KKG +V S+ D +++ + L+ G F +LK+ D I Sbjct: 10 ITGANQGIGKAIAKKLIKKGIQVIGTSTTEDGVKRINDYLE--GNGFGFVLNLKNIDSIT 67 Query: 65 LLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQAW 124 I+E ++ +ID L+ NA E + + +W + ++ + ++ +I++ Sbjct: 68 EKIQEIYKKKHSIDILINNAGIK--EDNLLVNMKSTEWDDVIKTNLSSVFHLVKSVIRSM 125 Query: 125 LEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLGSF 184 + KK +G II + S + +++GL+ K ++ KGI V G Sbjct: 126 I-KKRQGRIITIGSVIAYTGNKGQVNYSASKSGLIGFHKSLALEVASKGITVNIVSPGLI 184 Query: 185 DTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYMLG 244 T + ++ I ++ + P+KR G+ E+ + FL S+ A Y+ G Sbjct: 185 KTNFTEK------------LNSIQYQKYLSNIPMKRFGQKEEVADAVIFLASKKASYITG 232 Query: 245 STIVFDGAM 253 T+ +G M Sbjct: 233 HTLHVNGGM 241 >sp|P37079|SORD_KLEPN SORBITOL-6-PHOSPHATE 2-DEHYDROGENASE (GLUCITOL-6-PHOSPHATE DEHYDROGENASE) (KETOSEPHOSPHATE REDUCTASE) >gi|1073639|pir||S50186 sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) - Klebsiella pneumoniae >gi|43939|emb|CAA46856.1| (X66059) D-glucitol-6-P-Dehydrogenase [Klebsiella pneumoniae] >gi|1091866|prf||2022173B glucitol phosphate dehydrogenase [Klebsiella pneumoniae] Length = 267 Score = 73.4 bits (177), Expect = 3e-12 Identities = 71/264 (26%), Positives = 115/264 (42%), Gaps = 18/264 (6%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDD 62 I++T + GIG I ELL +G V + + ++ H++ D+ S + Sbjct: 12 IIVTGGASGIGLAIVDELLSQGAHVQMIDIHGG------DRHHNGDNYHFWSTDISSATE 65 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHE----ARYIDWLEAA---LLHIVAPG- 114 ++ I + ID LV NA V + E RY + EAA +++I G Sbjct: 66 VQQTIDAIIQRWSRIDGLVNNA-GVNFPRLLVDEKAPAGRY-ELNEAAFEKMVNINQKGV 123 Query: 115 YITTLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGI 174 + + + + K+ GVI+ +SS S LE +A L + S+ G GI Sbjct: 124 FFMSQAVARQMVKQRAGVIVNVSSESGLEGSEGQSCYAATKAALNSFTRSWSKELGKYGI 183 Query: 175 RAYTVLLGSFDTPGAR--ENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALID 232 R V G + G R E +A R +T++++ E + P+ R G+ SE+ + Sbjct: 184 RVVGVAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGKLSEVADFVC 243 Query: 233 FLLSENAEYMLGSTIVFDGAMTRG 256 +LLS A Y+ G T G TRG Sbjct: 244 YLLSARASYITGVTTNIAGGKTRG 267 >pir||A72395 oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima (strain MSB8) >gi|4980796|gb|AAD35385.1|AE001711_8 (AE001711) oxidoreductase, short chain dehydrogenase/reductase family [Thermotoga maritima] Length = 257 Score = 73.4 bits (177), Expect = 3e-12 Identities = 67/254 (26%), Positives = 112/254 (43%), Gaps = 17/254 (6%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI-GEIHYFKADLKSKDD 62 L+T +GIG IA+ L G V I N + R+ E++KE GE ++ D+ ++D Sbjct: 16 LVTGGGQGIGKAIAQALAAAGAAVLIMDINEETARRTVEEIKEKGGEADFYVGDVTKEED 75 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQ 122 +K+A + G +D V NA +G + C A W + +++V Sbjct: 76 CFGAVKKALDRWGKLDIGVNNA-GIG-DWCEAENYPVEKWKKVIDVNLVGVFLSAKAEFH 133 Query: 123 AWLEKKMRGVIIYLSSAS--VLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 A E+K G II ++S S ++ + ++AG++ L + ++ + GIR ++ Sbjct: 134 AMKERKY-GKIINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLAAEWAPYGIRVNSIS 192 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 G TP I + +W +D PL R G +L FL S ++ Sbjct: 193 PGYIRTP-------LIESPNVKDLVPLW----LDMIPLGRLGEVDDLIGAAIFLASPASD 241 Query: 241 YMLGSTIVFDGAMT 254 YM G +V DG T Sbjct: 242 YMTGHDLVIDGGYT 255 >gb|AAF69799.1|AF232010_1 (AF232010) peroxisomal trans 2-enoyl CoA reductase [Cavia sp.] Length = 302 Score = 73.4 bits (177), Expect = 3e-12 Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 33/264 (12%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI------GEIHYFKADL 57 ++T GIG IAKELL G V IAS D +R A E+LK E+ + ++ Sbjct: 22 IVTGGGTGIGKAIAKELLHLGCNVVIASRKFDRLRAAAEELKATLPPSNKAEVTPIQCNI 81 Query: 58 KSKDDIKLLIKEAWEAMGAIDALV-------WNAPNVGCEPCMAHEARYIDWLEAALLHI 110 + ++++ L+K G ID LV W++P W ++ Sbjct: 82 RKEEEVNNLMKSTLALYGKIDFLVNNGGGQFWSSP---------EHISSKGWHAVIETNL 132 Query: 111 VAPGYITTLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYG 170 Y+ +W+ K+ G I+ + +L P + + AR G+ L K ++ + Sbjct: 133 TGTFYMCKAAYNSWM-KEHGGAIVNI--IILLNGQPFVAHSGAARGGVYNLTKSLALGWA 189 Query: 171 GKGIRAYTVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGAL 230 GIR V G+ + A +N M + + + P KR G E+ +L Sbjct: 190 RSGIRINCVAPGTVYSQTAMDNYG--------DMGKTLFADAFQKIPAKRLGVPEEVSSL 241 Query: 231 IDFLLSENAEYMLGSTIVFDGAMT 254 + FLLS A ++ G + DG + Sbjct: 242 VCFLLSPAASFITGQLVNVDGGQS 265 >pir||S02299 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium Length = 262 Score = 72.2 bits (174), Expect = 6e-12 Identities = 64/258 (24%), Positives = 122/258 (46%), Gaps = 19/258 (7%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAY--EKLKEIG-EIHYFKADLKS 59 ++IT +S G+G ++A + +V + + ++ + E++K++G E K D+ Sbjct: 10 VVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEEIKKVGGEAIAVKGDVTV 69 Query: 60 KDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYITT 118 + D+ L++ A + G +D ++ NA G E P +HE DW + ++ + Sbjct: 70 ESDVINLVQSAIKEFGKLDVMINNA---GMENPVSSHEMSLSDWNKVIDTNLTGAFLGSR 126 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLE-PMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 I+ ++E ++G +I +SS + P P + ++ G+ + + ++ Y KGIR Sbjct: 127 EAIKYFVENDIKGTVINMSSVHEWKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 186 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 + G+ +TP E A EER +V P+ G E+ A + +L S Sbjct: 187 NIGPGAINTPINAEKFAD-PEERA---------DVESMIPMGYIGEPEEIAA-VAWLASS 235 Query: 238 NAEYMLGSTIVFDGAMTR 255 A Y+ G T+ DG MT+ Sbjct: 236 EASYVTGITLFADGGMTQ 253 >pir||JC5856 polyketide synthase (EC 2.-.-.-) chain 7 - Actinomadura hibisca >gi|2580448|dbj|BAA23150.1| (D87924) ORF 7 [Actinomadura hibisca] Length = 246 Score = 72.2 bits (174), Expect = 6e-12 Identities = 70/255 (27%), Positives = 112/255 (43%), Gaps = 25/255 (9%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEK--LKEIGEIHYFKADLKSKD 61 LIT +RGIG +A L + G V++ + A E G+ H +AD+ + Sbjct: 12 LITGGTRGIGRAVALGLARAGANVTVCYRSDAESAAAMEAELAATDGKHHVLQADIGNAG 71 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITT--L 119 D++ L+ E MG++D +V NA + P + D LE H + +T L Sbjct: 72 DVRRLLDEVAARMGSLDVVVHNAGLISHVP-------FAD-LEPEEWHRIVDSNLTGMYL 123 Query: 120 LIQAWLEKKMRG-VIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 +++A L G ++ + S L + A+AGL+ + +S+ G GIR Sbjct: 124 VVRAALPLLSEGGAVVGVGSKVALVGISQRTHYTAAKAGLIGFVRSLSKELGPLGIRVNL 183 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 V G +T A +L + ER +M T LKR G+ E+ ++ FL Sbjct: 184 VAPGITETDQAA-HLPPVQRERYQSM-----------TALKRLGQADEVADVVLFLAGPG 231 Query: 239 AEYMLGSTIVFDGAM 253 A Y+ G T+ DG M Sbjct: 232 ARYVTGETVNVDGGM 246 >dbj|BAB04651.1| (AP001510) 3-oxoacyl-(acyl-carrier protein) reductase [Bacillus halodurans] Length = 252 Score = 72.2 bits (174), Expect = 6e-12 Identities = 63/252 (25%), Positives = 120/252 (47%), Gaps = 13/252 (5%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDD 62 +L+T S+GIG IA+ +++G +V+I + + +++A +++G + +AD+ K++ Sbjct: 10 VLVTGGSKGIGKGIAQAFVEEGAKVAIVARDAHGLQEA---KRQLGNVLTIQADVTDKNE 66 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQ 122 + + + E G ID LV NA G + E + EA L+ + + + L + Sbjct: 67 REKVFSQLLETYGTIDILVNNAG--GSNGGLISETELSLFEEAFSLNYFSAVHFSQLALP 124 Query: 123 AWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLG 182 ++ K G II +SS E ++A+A ++ K ++ GIR + G Sbjct: 125 V-MKAKQSGAIINISSIFGRESGGKATY-NSAKAAMISFTKSLADEVIRDGIRVNGIAPG 182 Query: 183 SFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYM 242 S P N + EE M++ ++ + P R G E+ + FL SE A ++ Sbjct: 183 SILHPTG--NWQKRLEENREKMEQFIDQNI----PAGRFGTVEEIANVAVFLASEKASWV 236 Query: 243 LGSTIVFDGAMT 254 +G+T+ DG + Sbjct: 237 VGATLNVDGGQS 248 >sp|P07999|DHGB_BACME GLUCOSE 1-DEHYDROGENASE B Length = 262 Score = 71.4 bits (172), Expect = 1e-11 Identities = 62/258 (24%), Positives = 120/258 (46%), Gaps = 19/258 (7%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAY--EKLKEIG-EIHYFKADLKS 59 ++IT +S G+G ++A + +V + + ++ + E++K++G E K D+ Sbjct: 10 VVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEEIKKVGGEAIAVKGDVTV 69 Query: 60 KDDIKLLIKEAWEAMGAIDALVWNAPNVGCE-PCMAHEARYIDWLEAALLHIVAPGYITT 118 + D+ L++ A + G +D ++ NA G E P +HE DW + ++ + Sbjct: 70 ESDVINLVQSAIKEFGKLDVMINNA---GMENPVSSHEMSLSDWNKVIDTNLTGAFLGSR 126 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLE-PMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 I+ ++E ++G +I +SS + P P + ++ G+ + + ++ Y KGIR Sbjct: 127 EAIKYFVENDIKGTVINMSSVHEWKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 186 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 + G+ +TP E A D +V P+ G E+ A + +L S Sbjct: 187 NIGPGAINTPINAEKFA----------DPEQRADVESMIPMGYIGEPEEIAA-VAWLASS 235 Query: 238 NAEYMLGSTIVFDGAMTR 255 A Y+ G T+ DG MT+ Sbjct: 236 EASYVTGITLFADGGMTQ 253 >pir||T51721 sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) [imported] - Streptococcus mutans >gi|4928282|gb|AAD33518.1|AF132127_3 (AF132127) sorbitol-6-phosphate dehydrogenase [Streptococcus mutans] Length = 266 Score = 71.4 bits (172), Expect = 1e-11 Identities = 68/264 (25%), Positives = 120/264 (44%), Gaps = 19/264 (7%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDD 62 +++T AS GIG I ELL +V +A+ + + + +E L + K D+ S++ Sbjct: 12 VIVTGASSGIGKAIVDELLSL--KVKVANFDLTDNGEKHENLL------FQKVDVTSREQ 63 Query: 63 IKLLIKEAWEAMGAIDALVWNA----PNVGCEPCMAHEARYIDWLEAALLHIVAPG--YI 116 ++ + E G +DA+V NA P + +P H +D + ++ Y+ Sbjct: 64 VEASVAAVVEHFGTVDAVVNNAGINIPRLLVDPKDPHGQYELDDATFEKITMINQKGLYL 123 Query: 117 TTLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRA 176 + + L K +GVII ++S + LE +A + + ++ G G+R Sbjct: 124 VSQAVGRLLVAKKKGVIINMASEAGLEGSEGQSAYAGTKAAVYSYTRSWAKELGKYGVRV 183 Query: 177 YTVLLGSFDTPGARENLA---RIAEERGVTMDEIWEREV-IDRTPLKRTGRWSELGALID 232 + G + G R LA + RG T++EI TPL R+G+ SE+ L+ Sbjct: 184 VGIAPGIMEATGLR-TLAYEEALGYTRGKTVEEIRAGYASTTTTPLGRSGKLSEVADLVA 242 Query: 233 FLLSENAEYMLGSTIVFDGAMTRG 256 + +S+ + Y+ G T G TRG Sbjct: 243 YYISDRSSYITGITTNVAGGKTRG 266 >gb|AAF81239.1| (AF263012) putative beta-ketoacyl reductase [Streptomyces griseus subsp. griseus] Length = 274 Score = 71.4 bits (172), Expect = 1e-11 Identities = 63/257 (24%), Positives = 115/257 (44%), Gaps = 14/257 (5%) Query: 5 ITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLK-EIGEIHYFKADLKSKDDI 63 +T AS GIG +A L G V++ + + +R E+++ + G DL D + Sbjct: 17 LTGASSGIGAVLATMLAAHGSSVALMARSEKELRLLAERIEADGGRAVAVPGDLTDGDSV 76 Query: 64 KLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQA 123 + ++EA E +G ID LV A + + + W ++++ + ++ Sbjct: 77 RAAVREAEEQLGPIDRLVHCAGEARNQAFLCDQDEE-QWTATLDINLLGAFRVARAVVPG 135 Query: 124 WLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLGS 183 +E++ G I+ +SS + +P ++ GL + + ++ G G+R V G Sbjct: 136 MMERR-EGNIVMVSSIAGKRGLPANTSYCASKFGLNGMTQALASELGSFGVRVNAVCPGL 194 Query: 184 FDTPGAREN-------LARIAEERGVTMDEIWE---REVIDRTPLKRTGRWSELGALIDF 233 D+P A + +A IA+ G D WE R ++ T L+R R E+ A + F Sbjct: 195 TDSPAATDGGRYGDAFMAAIAKHHG-PPDLTWERYLRRAVNSTILRRLVRPEEIAAQVLF 253 Query: 234 LLSENAEYMLGSTIVFD 250 LLS+ + M G + D Sbjct: 254 LLSDLSGGMTGQAVNVD 270 >emb|CAB95802.1| (AL359949) putative short chain oxidoreductase [Streptomyces coelicolor A3(2)] Length = 253 Score = 71.4 bits (172), Expect = 1e-11 Identities = 68/255 (26%), Positives = 115/255 (44%), Gaps = 26/255 (10%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDDI 63 L+T ASRGIG+ +A+ L+ +G V I N D +++A ++L G K+ D+ Sbjct: 13 LVTGASRGIGYGVAEALVARGDRVCITGRNEDALKEAVDRL---GPDRVIGVAGKAHDEA 69 Query: 64 --KLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALL---HIVAPGYITT 118 + ++ EA G +D LV NA G P A +D A + ++++ Sbjct: 70 HQAVAVERVMEAFGRVDFLVNNA---GTNPVFGPIAD-LDLNVARKVFETNVISALGFAQ 125 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 AW +K G I+ ++S + L P P + ++A L+ L ++ + + +R Sbjct: 126 RTWHAW-QKDNGGAIVNIASVAGLSPSPFIAAYGVSKAALINLTAQLAHEFAPR-VRVNA 183 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 + T A A + E R E E PL R G S++G +FL SE Sbjct: 184 IAPAVVKTKFA----AALYEGR--------EEEAAAGYPLGRLGVPSDIGGAAEFLTSEQ 231 Query: 239 AEYMLGSTIVFDGAM 253 + ++ G T+V DG + Sbjct: 232 SAWVTGQTLVVDGGI 246 >emb|CAC11396.1| (AL445063) 3-ketoacyl-acyl carrier protein reductase related protein [Thermoplasma acidophilum] Length = 255 Score = 71.4 bits (172), Expect = 1e-11 Identities = 73/254 (28%), Positives = 117/254 (45%), Gaps = 25/254 (9%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDDI 63 LIT AS+G+G IA++ +G +V+I + N D K + GEI F+AD+ ++D I Sbjct: 11 LITGASKGLGRAIAEKFADEGAKVAI-NYNSDEKGALEVKRRTGGEI--FQADVSNRDQI 67 Query: 64 KLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQA 123 + + E +G ID LV N+ G M + +Y + ++ + G I T L Sbjct: 68 RRMANEIHSKLGKIDILVNNS---GIWYLMPFD-QYDESKVRRMIDVNLMGAIYTTLEFL 123 Query: 124 WLEKKMRGVIIYLSS-ASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLG 182 K+ RGVII ++S A + +AG++ L K ++ GIR + G Sbjct: 124 PDLKEKRGVIINMASNAGIGTAARNTTFYSITKAGIIMLTKRLAFDLSEYGIRVNAIAPG 183 Query: 183 SFDTP-----GARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 +T + E + R+ E + RT LK G+ +G FL S+ Sbjct: 184 WIETDLTIGGKSEEEIKRL------------EDDFRSRTTLKMIGKPEYIGNAAVFLASK 231 Query: 238 NAEYMLGSTIVFDG 251 ++EYM G +V DG Sbjct: 232 DSEYMNGQVMVIDG 245 >emb|CAB92206.1| (AL356592) putative oxidoreductase. [Streptomyces coelicolor A3(2)] Length = 263 Score = 71.0 bits (171), Expect = 1e-11 Identities = 71/254 (27%), Positives = 109/254 (41%), Gaps = 18/254 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 L+T A+ GIG A+ L G V +A N + KA +L+ G E + D+ + Sbjct: 23 LVTGAASGIGLATARRLGAGGARVVVADFNAEGAEKAAAELRAGGVEAAAVELDVTRPES 82 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQ 122 ++ + A + G++D V NA +G E + ++ Y + Sbjct: 83 VEAAVGFAVDTFGSLDLAVNNA-GIGGPSAPTGEYDVAAYQRVVRTNLDGVFYSMRYELP 141 Query: 123 AWLEKKMRGVIIYLSS--ASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 A G I+ ++S SV P +A A+ G+V L K + Y +GIR V Sbjct: 142 AIEAAGKGGSIVNVASILGSVGFAGSPAYVA--AKHGVVGLTKAAAAEYAARGIRINAVG 199 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 G DTP + TMDE + ++ P R GR E+ LI FLLS+ A Sbjct: 200 PGFIDTPLLK------------TMDEAAYKGLVALHPAGRLGRSEEVAELIAFLLSDRAS 247 Query: 241 YMLGSTIVFDGAMT 254 ++ GS + DGA T Sbjct: 248 FVAGSYHLVDGAYT 261 >sp|Q9X248|FABG_THEMA 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) >gi|7431037|pir||H72219 3-oxoacyl-(acyl carrier protein) reductase - Thermotoga maritima (strain MSB8) >gi|4982301|gb|AAD36790.1|AE001811_10 (AE001811) 3-oxoacyl-(acyl carrier protein) reductase [Thermotoga maritima] Length = 246 Score = 70.6 bits (170), Expect = 2e-11 Identities = 66/254 (25%), Positives = 116/254 (44%), Gaps = 22/254 (8%) Query: 4 LITAASRGIGFNIAKELLKKGHEV---SIASSNPDNIRKAYEKLKEIGEIHYFKADLKSK 60 LIT A+ GIG ++G V I+ N D++ K E L G++ + ++ + Sbjct: 9 LITGAASGIGKATTLLFAQEGATVIAGDISKENLDSLVKEAEGLP--GKVDPYVLNVTDR 66 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPG-YITTL 119 D IK ++++ + G ID LV NA + + DW A++++ G + T Sbjct: 67 DQIKEVVEKVVQKYGRIDVLVNNAGIT--RDALLVRMKEEDW--DAVINVNLKGVFNVTQ 122 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 ++ ++ K+ G I+ +SS + P ++AG++ + K ++ G+ IR V Sbjct: 123 MVVPYMIKQRNGSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKELAGRNIRVNAV 182 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G +TP E L A E ++ R PL R G+ E+ +I FL S+ + Sbjct: 183 APGFIETP-MTEKLPEKARETALS-----------RIPLGRFGKPEEVAQVILFLASDES 230 Query: 240 EYMLGSTIVFDGAM 253 Y+ G I DG + Sbjct: 231 SYVTGQVIGIDGGL 244 >pir||T36264 probable dehydrogenase - Streptomyces coelicolor >gi|5123661|emb|CAB45350.1| (AL079345) putative dehydrogenase [Streptomyces coelicolor A3(2)] Length = 258 Score = 70.6 bits (170), Expect = 2e-11 Identities = 62/255 (24%), Positives = 111/255 (43%), Gaps = 19/255 (7%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEI-HYFKADLKSKD 61 ++I GIG +I + G V++A + +A ++L+ G + H D++S++ Sbjct: 13 LVIGGGGAGIGRSIVRSCAAAGAAVAVADVDAARATEAADELRAAGHVAHALSGDVRSRE 72 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPN-VGCEPCMA-HEARYIDWLEAALLHIVAPGYITTL 119 ++ +I A + +G +D L+ V P + HE DW L++ Sbjct: 73 QLEDVIVGAADRLGGLDVLITVVGGQVAFVPAVRLHEMADADWDTVYELNLRYVARAVRR 132 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 +++ +LE+ G I+ + S + P A+AGL LA+ ++ Y GIR V Sbjct: 133 VLRLFLEQGTGGNIVGIGSVTGFMAAPMQAGYGAAKAGLHSLARTVAAEYAADGIRMNVV 192 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G+ T A G + + W E+ P R G E+ A +L S+ + Sbjct: 193 AGGAIST----------AVNAGPS--DAWVPEI----PAGRYGTSEEMAAAAVYLASDES 236 Query: 240 EYMLGSTIVFDGAMT 254 Y+ G IV DG ++ Sbjct: 237 RYVTGQQIVLDGGVS 251 >gb|AAD42688.1|AF037323_1 (AF037323) D-beta-hydroxybutyrate dehydrogenase [Rhodobacter sp. DSMZ 12077] Length = 257 Score = 70.6 bits (170), Expect = 2e-11 Identities = 68/256 (26%), Positives = 111/256 (42%), Gaps = 10/256 (3%) Query: 2 RILITAASRGIGFNIAKELLKKGHEVSIAS-SNPDNIRKAYEKL-KEIG-EIHYFKADLK 58 R ++T ++ GIG A+EL + G EV I S ++ D EK+ +E G Y AD+ Sbjct: 7 RAIVTGSNSGIGLGCAEELARAGAEVVINSFTDRDEDHALAEKIGREHGVSCRYIAADMS 66 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITT 118 + + LI+ A G D LV NA G + + E + A L ++ + TT Sbjct: 67 DGEACRALIETA----GGCDILVNNA---GIQHVSSIEEFPVGKWNAILAINLSSAFHTT 119 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 + K G I+ ++SA L P A+ G+V K + GKGI Sbjct: 120 AAALPGMRAKGWGRIVNIASAHGLTASPYKSAYVAAKHGVVGFTKVTALETAGKGITCNA 179 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 + G TP + + + + + ++DR P ++ ++G + FL S Sbjct: 180 ICPGYVLTPLVEAQIPDQMKAHDMDRETVIREVMLDRQPSRQFATTGQIGGTVVFLCSGA 239 Query: 239 AEYMLGSTIVFDGAMT 254 A+ + G+TI DG T Sbjct: 240 ADQITGTTISVDGGWT 255 >gb|AAC95202.1| (AC004561) putative tropinone reductase [Arabidopsis thaliana] Length = 271 Score = 70.2 bits (169), Expect = 2e-11 Identities = 60/256 (23%), Positives = 112/256 (43%), Gaps = 15/256 (5%) Query: 1 MRILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKS 59 M L+T S+GIG + +EL G + + + ++++ K + G ++ D+ S Sbjct: 19 MTALVTGGSKGIGEAVVEELATLGARIHTCARDETQLQESLRKWQAKGFQVTTSVCDVSS 78 Query: 60 KDDIKLLIKEAWEAM-GAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITT 118 +D + L++ G ++ LV N +P + H A + A L + + Sbjct: 79 RDKREKLMETVSTIFEGKLNILVNNVGTCIVKPTLQHTAEDFSFTMATNLE---SAFHLS 135 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 L L+ G I+ +SS S + + + ++ + QL + ++ + IR + Sbjct: 136 QLAHPLLKASGSGSIVLISSVSGVVHVNGASIYGVSKGAMNQLGRNLACEWASDNIRTNS 195 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 V +TP E+L+ +E + +EV R P+ R G +E+ +L+ FL Sbjct: 196 VCPWFIETPLVTESLS----------NEEFRKEVESRPPMGRVGEVNEVSSLVAFLCLPA 245 Query: 239 AEYMLGSTIVFDGAMT 254 A Y+ G TI DG T Sbjct: 246 ASYITGQTICVDGGFT 261 >pir||E81695 3-oxoacyl-(acyl carrier protein) reductase TC0508 [imported] - Chlamydia muridarum (strain Nigg) >gi|7190547|gb|AAF39350.1| (AE002319) 3-oxoacyl-(acyl carrier protein) reductase [Chlamydia muridarum] Length = 248 Score = 70.2 bits (169), Expect = 2e-11 Identities = 64/255 (25%), Positives = 104/255 (40%), Gaps = 23/255 (9%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKL--KEIGEIHYFKADLKSKD 61 ++T SRGIGF IAK + G V I N + + A + L K ++ + D+ D Sbjct: 11 IVTGGSRGIGFGIAKLFAEHGANVQIWGINEEAGKSAAQDLSDKTGSKVSFALVDVSKND 70 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 + +++ G ID +V NA M +W ++ + + + +I Sbjct: 71 MVSAQVQKFLAEYGTIDVVVNNAGITRDSLLMRMSEE--EWSSVIDTNLGSIYNVCSAVI 128 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 + + K G I+ +SS L P A+AG++ +K +S+ G K IR + Sbjct: 129 RPMI-KARSGAIVNISSIVGLRGSPGQTNYAAAKAGIIGFSKALSKEVGSKNIRVNCIAP 187 Query: 182 GSFD---TPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 G D T G +NL + E + PL R G E+ FL S Sbjct: 188 GFIDTDMTKGLSDNL---------------KNEWLKGVPLGRVGTPEEIAMAALFLASNQ 232 Query: 239 AEYMLGSTIVFDGAM 253 + Y+ G + DG M Sbjct: 233 SSYITGQVLSVDGGM 247 >pir||E83207 probable short-chain dehydrogenase PA3511 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949658|gb|AAG06899.1|AE004771_8 (AE004771) probable short-chain dehydrogenase [Pseudomonas aeruginosa] Length = 253 Score = 70.2 bits (169), Expect = 2e-11 Identities = 62/259 (23%), Positives = 114/259 (43%), Gaps = 30/259 (11%) Query: 2 RILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSK 60 R+L+T +RG+G+ A+ + G V IA + ++++ +L E G +I DL Sbjct: 11 RVLLTGGARGLGYAFAEAAARAGARVVIADILEERVQRSARELAEQGLDISGLPLDLADP 70 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAP--NVGCEPCMAHEARYIDWLEAALLHIVAPGYITT 118 I+ + A E +G +D LV NA N G + C E I+ + L V ++ T Sbjct: 71 VSIERCVAAAVERLGGLDGLVNNASITNSGGKSC---EELEIEVFDRVLQVNVRGTWLMT 127 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 L + RG ++ L+S + L P L+ ++ L+ + + ++R GG GI Sbjct: 128 RACLPALRESGRGAVVNLASDTPLWGAPNLLAYSASKGALIAMTRSLARELGGDGITVNA 187 Query: 179 VLLGSFD------TPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALID 232 + G + P AR L R ++ L+R + +++ + Sbjct: 188 IAPGLVEVEATEYVPAARHRLYR------------------EQRALQRGQQPADVCGAVL 229 Query: 233 FLLSENAEYMLGSTIVFDG 251 F LS+ + ++ G T+ +G Sbjct: 230 FALSDLSRFITGQTLPVNG 248 >sp|P33207|FABG_ARATH 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE PRECURSOR (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) >gi|99753|pir||S22416 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) precursor - Arabidopsis thaliana >gi|16205|emb|CAA45794.1| (X64464) 3-oxoacyl-[acyl-carrier protein] reductase [Arabidopsis thaliana] Length = 319 Score = 69.9 bits (168), Expect = 3e-11 Identities = 67/256 (26%), Positives = 111/256 (43%), Gaps = 22/256 (8%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI----GEIHYFKADLK 58 ++IT ASRGIG IA L K G +V + + + ++A E K+I G+ F D+ Sbjct: 79 VVITGASRGIGKAIALALGKAGCKVLVNYAR--SAKEAEEVAKQIEEYGGQAITFGGDVS 136 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITT 118 D+ ++K A + G ID +V NA + + W E L++ T Sbjct: 137 KATDVDAMMKTALDKWGTIDVVVNNAGIT--RDTLLIRMKQSQWDEVIALNLTGVFLCTQ 194 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 ++ ++KK RG II +SS L + G++ ++ +R + I Sbjct: 195 AAVKIMMKKK-RGRIINISSVVGLIGNIGQANYTATKGGVISFSETPAREGASRNINVNV 253 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFL-LSE 237 V G IA + + E E++++ PL R G+ E+ L++FL LS Sbjct: 254 VCPGF------------IASDMTAELGEDMEKKILGTIPLGRYGKAEEVAGLVEFLALSP 301 Query: 238 NAEYMLGSTIVFDGAM 253 A Y+ G DG + Sbjct: 302 AASYITGQAFTIDGGI 317 >sp|P38004|FABG_CHLTR 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) >gi|7430986|pir||F71538 probable oxoacyl (carrier protein) reductase - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3328647|gb|AAC67830.1| (AE001297) Oxoacyl (Carrier Protein) Reductase [Chlamydia trachomatis] Length = 248 Score = 69.9 bits (168), Expect = 3e-11 Identities = 61/252 (24%), Positives = 106/252 (41%), Gaps = 17/252 (6%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG--EIHYFKADLKSKD 61 ++T SRGIGF+IAK ++G V I N + + A + L E ++ + D+ D Sbjct: 11 IVTGGSRGIGFSIAKLFAEQGANVQIWGINGEAGQAAAQTLSEQTGRQVSFALVDVSKND 70 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 + ++ ID +V NA M +W ++ + + + +I Sbjct: 71 MVSAQVQNFLAEYNTIDVIVNNAGITRDALLMRMSEE--EWSSVINTNLGSIYNVCSAVI 128 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 + + K G II +SS L P A+AG++ +K +S+ G K IR + Sbjct: 129 RPMI-KARSGAIINISSIVGLRGSPGQTNYAAAKAGIIGFSKALSKEVGSKNIRVNCIAP 187 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEY 241 G DT + ++++ + E + PL R G E+ FL S+ + Y Sbjct: 188 GFIDTDMTK------------SLNDNLKNEWLKGVPLGRVGMPEEIAKAALFLASDGSSY 235 Query: 242 MLGSTIVFDGAM 253 + G + DG M Sbjct: 236 ITGQVLSVDGGM 247 >pir||T36782 probable gluconate dehydrogenase - Streptomyces coelicolor >gi|5441755|emb|CAB46779.1| (AL096811) putative gluconate dehydrogenase [Streptomyces coelicolor A3(2)] Length = 253 Score = 69.9 bits (168), Expect = 3e-11 Identities = 68/255 (26%), Positives = 107/255 (41%), Gaps = 23/255 (9%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDDI 63 L+T +SRGIG +A+ L + G V + + D + KA L GE+H D+ + Sbjct: 15 LVTGSSRGIGLALARGLAEAGCRVILNGRDGDRLAKAAAGLP--GEVHTAVFDVTDGPSV 72 Query: 64 KLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQA 123 I EA E +G +D LV NA M A +++ +A I+ T L+ Sbjct: 73 TAGIAEAEERVGPLDILVNNAG-------MQLRAPLLEFADADWHRILDTNLTTAFLVGR 125 Query: 124 WLEKKM----RGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 ++M G I+ + S P + + L L KG+ +G G++ + Sbjct: 126 EAARRMTERGHGKIVNICSLQSEVVRPGIAPYAATKGALKMLTKGMCADWGPYGVQVNGL 185 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G +T R + DE + V RTP R GR +L + FL S A Sbjct: 186 GPGYIETELTRP----------LVEDEEFSTWVRGRTPAGRWGRTEDLVGGLLFLASPAA 235 Query: 240 EYMLGSTIVFDGAMT 254 +++ G + DG MT Sbjct: 236 DFVGGQILYVDGGMT 250 >pir||D75472 oxidoreductase, short-chain dehydrogenase/reductase family - Deinococcus radiodurans (strain R1) >gi|6458534|gb|AAF10397.1|AE001936_6 (AE001936) oxidoreductase, short-chain dehydrogenase/reductase family [Deinococcus radiodurans] Length = 266 Score = 69.9 bits (168), Expect = 3e-11 Identities = 63/250 (25%), Positives = 115/250 (45%), Gaps = 21/250 (8%) Query: 2 RILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKD 61 R L+T S+GIG A++L + G EV++A+ + +R+A E +IG + AD+ + + Sbjct: 34 RALVTGGSKGIGLAAARQLRELGAEVTLAARGEETLRRAAE---DIGAA-WVVADVSTPE 89 Query: 62 DIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLI 121 +K+ A +A G +D LV NA G P + E W + ++ + ++ Sbjct: 90 GVKV----AADAAGQVDILVSNAG--GPPPSLPSEVTEAAWEQGFQTTFLSTARLVDAVL 143 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 E++ G II ++S +V P L +++ RA + + ++ G+ TV Sbjct: 144 PGMRERRW-GRIIAITSLTVGRPSLTLPVSNALRAAVTNHLRTLALEVAADGVTCNTVAP 202 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEY 241 G T ++ A AE ++ + P +R G E+ + I FL + A Y Sbjct: 203 GYTATERLQKLHADPAE----------ADKLRAKIPARRFGEPDEVASAIAFLATNEAAY 252 Query: 242 MLGSTIVFDG 251 + G ++ DG Sbjct: 253 ITGQELLVDG 262 >pir||E82748 tropinone reductase XF0913 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9105832|gb|AAF83723.1|AE003930_13 (AE003930) tropinone reductase [Xylella fastidiosa] Length = 261 Score = 69.9 bits (168), Expect = 3e-11 Identities = 65/255 (25%), Positives = 109/255 (42%), Gaps = 16/255 (6%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEI---GEIHYFKADLKSK 60 LIT AS GIG +A+ELL G +V + + N D + + ++L E E+H AD+ Sbjct: 17 LITGASTGIGLAVARELLGLGADVLLVARNADLLGRVRDELAEEFPERELHGLAADVADD 76 Query: 61 DDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL 120 D + ++ + + L+ NA G A E +W E +++ + + Sbjct: 77 VDRRAILDWVEDCSNGLHVLINNAG--GNVTRAALEYTEDEWREIFEINLFS-AFELCRY 133 Query: 121 IQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVL 180 Q L I+ + S S L + + ++A L Q+ + ++ + GIR V Sbjct: 134 TQPLLACHASTAIVNIGSVSGLTHVRSGVPYGMSKAALHQMTRNLAVEWAEDGIRVNAVA 193 Query: 181 LGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAE 240 T E L+ D + +VI+RTP++R G E+ A + FL + Sbjct: 194 PWYIRTRRTSEPLS----------DVYYYEQVIERTPMRRIGEPEEVAAAVAFLCLPASS 243 Query: 241 YMLGSTIVFDGAMTR 255 Y+ G I DG R Sbjct: 244 YVTGECIAVDGGFMR 258 >pir||F82954 probable short-chain dehydrogenase PA5524 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951862|gb|AAG08909.1|AE004965_1 (AE004965) probable short-chain dehydrogenase [Pseudomonas aeruginosa] Length = 260 Score = 69.5 bits (167), Expect = 4e-11 Identities = 67/246 (27%), Positives = 107/246 (43%), Gaps = 22/246 (8%) Query: 11 GIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDDIKLLIKE 69 GIGF IA+ L ++G + I +S+ + IR+ E+L G ++ ADL + ++ L+ Sbjct: 22 GIGFAIARRLAREGVRLLITASS-ERIRQRAEELSACGHDVRAASADLTDEAQVQGLLDW 80 Query: 70 AWEAMGAIDALVWNAPNV---GCEPCMAHEARYI-DWLEAALLHIVAPGYITTLLIQAWL 125 A G +D LV NA EP A EA + DW + ++ + +T L+ Sbjct: 81 AEAQWGRVDILVNNAGMAQLDSAEPFSAVEATSLRDWQLSLSRNLTSAFLLTRGLLPGMR 140 Query: 126 EKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLGSFD 185 E+ ++ S+ P A+AGLV + G++ GI +V Sbjct: 141 ERGYGRIVNVASTTGTRGSNPGEAAYSAAKAGLVGWSMGLALEVAKSGITVNSV------ 194 Query: 186 TPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYMLGS 245 PG + AEER + +P R GR E+ A + FL S A ++ G Sbjct: 195 APGWIATASSTAEERQAAL----------ASPSGRAGRPEEVAAAVAFLASPEASFVNGE 244 Query: 246 TIVFDG 251 +V DG Sbjct: 245 LLVVDG 250 >dbj|BAB06901.1| (AP001518) 3-oxoacyl-[acyl-carrier protein] reductase [Bacillus halodurans] Length = 252 Score = 69.5 bits (167), Expect = 4e-11 Identities = 61/255 (23%), Positives = 113/255 (43%), Gaps = 19/255 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYE----KLKEIGEIHYFKADLKS 59 L+T+ ++G+G + K LLKKG+ V+++ D K E LK+ I + D+ Sbjct: 5 LVTSGTKGLGVQVTKALLKKGYTVTVSYRTEDEAMKQLETTWGHLKD--RIQLVQVDVTK 62 Query: 60 KDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTL 119 K+DI L+ A++ G ID +V NA E + +W ++ A Y+ Sbjct: 63 KEDIYRLVDGAYDRFGRIDVVVNNAGPYIFERKKLFDYEEHEWQTMVNGNLSAAFYMFKK 122 Query: 120 LIQAWLEKKMRGVIIY-LSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 ++ ++ +I+Y A+ A+ GLV L K ++ GI Sbjct: 123 VLPIMRNQQFGRIILYGFQGANTAPAWLYRSAYAAAKVGLVSLMKTVAVEEAEYGITVNM 182 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 V G+ + E + T++E +++ D TP+ R+G ++ + FL ++ Sbjct: 183 VCPGNI-----------VGEMKEATIEESRKQKDPD-TPIGRSGTGEDIARTVAFLCEDD 230 Query: 239 AEYMLGSTIVFDGAM 253 ++ + GS I GA+ Sbjct: 231 SDMVTGSVIEVTGAV 245 >pir||T32002 hypothetical protein F36H9.3 - Caenorhabditis elegans >gi|2315645|gb|AAB66092.1| (AF016668) strong similarity to the insect-type alcohol dehydrogenase family [Caenorhabditis elegans] Length = 257 Score = 69.1 bits (166), Expect = 5e-11 Identities = 65/252 (25%), Positives = 110/252 (42%), Gaps = 15/252 (5%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLK-EIGEIHYFKADLKSKDD 62 L+TA+++GIGF IAK+L G V + S +N+ +A L+ E + H A + +K D Sbjct: 15 LVTASTKGIGFAIAKQLGAAGASVVVCSRKKENVDEAVAALRLENIDAHGTTAHVGNKSD 74 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHI-VAPGYITTLLI 121 LI + +D LV NA P + D LL + V + T Sbjct: 75 RTKLIDFTLDRFTKLDILVSNA---AVNPHYGDLMKVTDSQWDKLLDLNVKSAFELTKEA 131 Query: 122 QAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLL 181 LE RG ++++SS + PM + + L L+K ++ + IR ++ Sbjct: 132 VPHLEASGRGNVVFVSSVAGYSPMNEIGAYSVMKTTLTGLSKSLALNLARRNIRVNSIAP 191 Query: 182 GSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEY 241 G T ++ + DE +++ + + +R G E + FL+S+ A Y Sbjct: 192 GIIQTDFSQV----------LFSDESEKQKWLSQIAQRRFGDPDECAEAVAFLVSDEASY 241 Query: 242 MLGSTIVFDGAM 253 + G TI +G M Sbjct: 242 ISGETIGINGGM 253 >gb|AAF24130.1|AF129168_3 (AF129168) D-sorbitol-6-phosphate dehydrogenase [Lactobacillus casei] Length = 266 Score = 69.1 bits (166), Expect = 5e-11 Identities = 66/266 (24%), Positives = 117/266 (43%), Gaps = 23/266 (8%) Query: 3 ILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDD 62 I++T S GIG I KELL+ G V + + + YFK D+ + ++ Sbjct: 12 IIVTGGSSGIGEAIVKELLQNGANVVNGDLKKGTLEDQH--------LTYFKTDVTNPEE 63 Query: 63 IKLLIKEAWEAMGAIDALVWNA----PNVGCEPCMAH-----EARYIDWLEAALLHIVAP 113 ++ L EA + G I +V NA P V +P H +AR D + + V Sbjct: 64 VENLAAEAEKINGEIWGVVNNAGINKPRVLVDPTEPHGKYELDARTFDQIFNVNVKSV-- 121 Query: 114 GYITTLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKG 173 ++ + + K+ GVI+ +SS + LE + ++ + + ++ G Sbjct: 122 -FLVSQAAARRMVKQHHGVIVNMSSEAGLEGSVGQSVYSASKGAINGFTRSWAKELGKYN 180 Query: 174 IRAYTVLLGSFDTPGAR--ENLARIAEERGVTMDEIWER-EVIDRTPLKRTGRWSELGAL 230 IR V G + G R + +A R T++ I + TP+ R+G+ +E+ L Sbjct: 181 IRVVGVAPGIMEATGLRTPDYEEALAYTRDTTVEAIRAGYKSTSTTPMGRSGKLTEVADL 240 Query: 231 IDFLLSENAEYMLGSTIVFDGAMTRG 256 +++ +S+ A Y+ G T G +RG Sbjct: 241 VNYFVSDRASYITGVTTNVAGGKSRG 266 >sp|P16544|ACT3_STRCO PUTATIVE KETOACYL REDUCTASE >gi|80725|pir||A28788 actinorhodin polyketide ketoreductase (EC 1.1.1.-) actIII - Streptomyces coelicolor >gi|153142|gb|AAA26688.1| (M19536) actIII protein [Streptomyces coelicolor] Length = 261 Score = 68.7 bits (165), Expect = 7e-11 Identities = 59/240 (24%), Positives = 111/240 (45%), Gaps = 9/240 (3%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 L+T A+ GIG IA+ L K+G V + + + +R ++L+E G E D++S + Sbjct: 10 LVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRSVPE 69 Query: 63 IKLLIKEAWEAMGAIDALVWNA--PNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLL 120 I+ L+ E G +D LV NA P G +A E WL+ ++ +T + Sbjct: 70 IEALVAAVVERYGPVDVLVNNAGRPGGGATAELADEL----WLDVVETNLTGVFRVTKQV 125 Query: 121 IQA-WLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 ++A + ++ G I+ ++S + + ++ G+V K + GI V Sbjct: 126 LKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSASKHGVVGFTKALGLELARTGITVNAV 185 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G +TP A ++ V+ +E ++R + R P+ R + SE+ ++ +L+ A Sbjct: 186 CPGFVETPMAASVREHYSDIWEVSTEEAFDR-ITARVPIGRYVQPSEVAEMVAYLIGPGA 244 >sp|Q11020|Y07E_MYCTU PUTATIVE OXIDOREDUCTASE RV1350 >gi|7431079|pir||E70740 probable fabG2 protein - Mycobacterium tuberculosis (strain H37RV) >gi|1419053|emb|CAA99983.1| (Z75555) fabG2 [Mycobacterium tuberculosis] Length = 247 Score = 68.7 bits (165), Expect = 7e-11 Identities = 61/248 (24%), Positives = 106/248 (42%), Gaps = 15/248 (6%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIGEIHYFKADLKSKDDI 63 +IT ++G+G I + + +G V + N + A ++L + D+ DD+ Sbjct: 11 VITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDV 70 Query: 64 KLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQA 123 +LI+ A E G +D +V NA D + A L G T L A Sbjct: 71 DILIRTAVERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNG---TRLAAA 127 Query: 124 WLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLGS 183 + ++ RG I+ +SS S M A+AG+V + K ++ GIR + G Sbjct: 128 IMRERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGL 187 Query: 184 FDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYML 243 R + +R IW++++ + P+ R G SE+ ++ FL S+ + YM Sbjct: 188 I-----RSAMTEAMPQR------IWDQKLAE-VPMGRAGEPSEVASVAVFLASDLSSYMT 235 Query: 244 GSTIVFDG 251 G+ + G Sbjct: 236 GTVLDVTG 243 >pir||H70706 probable OXIDOREDUCTASE - Mycobacterium tuberculosis (strain H37RV) >gi|1550643|emb|CAB02395.1| (Z80226) hypothetical protein Rv0765c [Mycobacterium tuberculosis] Length = 275 Score = 68.7 bits (165), Expect = 7e-11 Identities = 46/177 (25%), Positives = 86/177 (47%), Gaps = 4/177 (2%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLK-EIGEIHYFKADLKSKDD 62 ++ AS GIG A EL +G V++ + D + + +K++ + GE F D+ + Sbjct: 14 VVAGASSGIGAATATELAGRGFPVALGARRMDKLAELVDKIRADGGEAVAFPLDVTDPES 73 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQ 122 +K + + EA+G ++ LV +A ++ P HE + E +H+V + T ++ Sbjct: 74 VKSFVAQTVEALGEVELLVSSAGDM--LPGQLHEVSTEAFAEQVQIHLVGANRLATAVLP 131 Query: 123 AWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 A + ++ RG +I++ S L P + A+AGL + + G G+RA V Sbjct: 132 AMVARR-RGDLIFVGSDVGLRQRPHMGAYGAAKAGLAAMVTNLQMELEGTGVRASIV 187 >gb|AAC95204.1| (AC004561) putative tropinone reductase [Arabidopsis thaliana] Length = 262 Score = 68.7 bits (165), Expect = 7e-11 Identities = 60/256 (23%), Positives = 115/256 (44%), Gaps = 15/256 (5%) Query: 1 MRILITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKS 59 M L+T + GIG+ I +EL G + + + + ++ + ++ G ++ D+ S Sbjct: 10 MTALVTGGASGIGYAIVEELAGFGARIHVCDISEAKLNQSLSEWEKKGFQVSGSVCDVAS 69 Query: 60 KDDIKLLIKEAWEAM-GAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITT 118 + + + L++ G ++ LV N + +P + D + V Y + Sbjct: 70 RPEREELMQTVSSQFDGKLNILVSNVGVIRSKPTTEYTE---DDFAFHISSNVEAAYHFS 126 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 L L+ G II++SS + + + + L+QLAK ++ + GIRA Sbjct: 127 QLSHPLLKASGYGSIIFVSSIAGVISFDAGSIYGLTKGALIQLAKNLACEWAKDGIRANA 186 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 V +TP ++ L ++ +++ ++ RTPL R G +E+ +L+ FL Sbjct: 187 VAPNVINTPLSQSYLEDVS----------FKKALLSRTPLGRVGEPNEVASLVAFLCLPA 236 Query: 239 AEYMLGSTIVFDGAMT 254 A Y+ G TI DG +T Sbjct: 237 ASYITGQTICVDGGLT 252 >gb|AAF69798.1|AF232009_1 (AF232009) peroxisomal trans 2-enoyl CoA reductase [Homo sapiens] Length = 303 Score = 68.7 bits (165), Expect = 7e-11 Identities = 56/254 (22%), Positives = 110/254 (43%), Gaps = 18/254 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLK------EIGEIHYFKADL 57 ++T + GIG I KELL+ G V IAS + ++ A ++L+ + + + ++ Sbjct: 22 IVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNI 81 Query: 58 KSKDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYIT 117 ++++++ L+K + G I+ LV N P A W ++ Y+ Sbjct: 82 RNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP--AEHISSKGWHAVLETNLTGTFYMC 139 Query: 118 TLLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAY 177 + +W+++ ++ + P + + ARAG+ L K ++ + GIR Sbjct: 140 KAVYSSWMKEHGGSIVNIIVPTKA--GFPLAVHSGAARAGVYNLTKSLALEWACSGIRIN 197 Query: 178 TVLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSE 237 V G + A EN + + + + P KR G E+ +++ FLLS Sbjct: 198 CVAPGVIYSQTAVENYG--------SWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSP 249 Query: 238 NAEYMLGSTIVFDG 251 A ++ G ++ DG Sbjct: 250 AASFITGQSVDVDG 263 >gb|AAG10026.1|AF282240_10 (AF282240) cyclohexanol dehydrogenase [Acinetobacter sp. SE19] Length = 251 Score = 68.7 bits (165), Expect = 7e-11 Identities = 67/252 (26%), Positives = 111/252 (43%), Gaps = 18/252 (7%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 LIT A GIG + A L ++G V ++ N + +K +++ +G + KA+ +D Sbjct: 15 LITGAGSGIGKSTALLLAQQGVSVVVSDINLEAAQKVVDEIVALGGKAAANKANTAEPED 74 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITTLLIQ 122 +K ++ A GA+ NA +G E E W +++ A Y + Sbjct: 75 MKAAVEFAVSTFGALHLAFNNAGILG-EVNSTEELSIEGWRRVIDVNLNAVFYSMHYEVP 133 Query: 123 AWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTVLLG 182 A L G I+ +S + L + + A+ G+ L K + Y KGIR +V G Sbjct: 134 AILAAG-GGAIVNTASIAGLIGIQNISGYVAAKHGVTGLTKAAALEYADKGIRINSVHPG 192 Query: 183 SFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENAEYM 242 TP + E E E++ P+ R G+ E+ ++ FLLS++A ++ Sbjct: 193 YIKTP---------------LIAEFEEAEMVKLHPIGRLGQPEEVAQVVAFLLSDDASFV 237 Query: 243 LGSTIVFDGAMT 254 GS V DGA T Sbjct: 238 TGSQYVVDGAYT 249 >gi|8923752 peroxisomal trans 2-enoyl CoA reductase; putative short chain alcohol dehydrogenase [Homo sapiens] >gi|7688188|emb|CAB89810.1| (AJ250303) alcohol dehydrogenase, short chain [Homo sapiens] Length = 303 Score = 68.3 bits (164), Expect = 9e-11 Identities = 56/253 (22%), Positives = 109/253 (42%), Gaps = 18/253 (7%) Query: 5 ITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLK------EIGEIHYFKADLK 58 +T + GIG I KELL+ G V IAS + ++ A ++L+ + + + +++ Sbjct: 23 VTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIR 82 Query: 59 SKDDIKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYIDWLEAALLHIVAPGYITT 118 +++++ L+K + G I+ LV N P A W ++ Y+ Sbjct: 83 NEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSP--AEHISSKGWHAVLRTNLTGSFYMCK 140 Query: 119 LLIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYT 178 + +W+++ ++ + P + + ARAG+ L K ++ + GIR Sbjct: 141 AVYSSWMKEHGGSIVNIIVPTKA--GFPLAVHSGAARAGVYNLTKSLALEWACSGIRINC 198 Query: 179 VLLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSEN 238 V G + A EN + + + + P KR G E+ +++ FLLS Sbjct: 199 VAPGVIYSQTAVENYG--------SWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPA 250 Query: 239 AEYMLGSTIVFDG 251 A ++ G ++ DG Sbjct: 251 ASFITGQSVDVDG 263 >gb|AAF70104.1|AF257324_5 (AF257324) AknA [Streptomyces galilaeus] Length = 261 Score = 68.3 bits (164), Expect = 9e-11 Identities = 60/240 (25%), Positives = 108/240 (45%), Gaps = 9/240 (3%) Query: 4 LITAASRGIGFNIAKELLKKGHEVSIASSNPDNIRKAYEKLKEIG-EIHYFKADLKSKDD 62 ++T A+ GIG +A+ L + G V I + + D + ++L+E G ++ D++ Sbjct: 10 IVTGATSGIGLAVARSLAEGGARVFICARDGDRVAHTVKELREAGHDVDGASCDVRDTAR 69 Query: 63 IKLLIKEAWEAMGAIDALVWNAPNVGCEPCMAHEARYID--WLEAALLHIVAPGYIT-TL 119 ++ ++EA + G +DALV NA G H A+ D WL+ ++ + +T + Sbjct: 70 VRAFVQEARDRFGPVDALVNNAGRSG----GGHTAQIADELWLDVIETNLNSVFRMTREV 125 Query: 120 LIQAWLEKKMRGVIIYLSSASVLEPMPPLILADTARAGLVQLAKGISRTYGGKGIRAYTV 179 L + ++ G I+ ++S + + ++ G+V K + GI V Sbjct: 126 LTTGGMLERGAGRIVNIASTGGKQGVALGAPYSASKHGVVGFTKALGLELAKTGITVNAV 185 Query: 180 LLGSFDTPGARENLARIAEERGVTMDEIWEREVIDRTPLKRTGRWSELGALIDFLLSENA 239 G +TP A A +T DE+ ER + PL R E+ L+ +LLS A Sbjct: 186 CPGYVETPMAERVRQGYAGAWDITEDEVLER-FEAKIPLGRYSTPDEVAGLVGYLLSSTA 244 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.137 0.404 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 96009945 Number of Sequences: 2977 Number of extensions: 3772081 Number of successful extensions: 12156 Number of sequences better than 1.0e-10: 92 Number of HSP's better than 0.0 without gapping: 3 Number of HSP's successfully gapped in prelim test: 89 Number of HSP's that attempted gapping in prelim test: 12015 Number of HSP's gapped (non-prelim): 93 length of query: 259 length of database: 189,106,746 effective HSP length: 54 effective length of query: 205 effective length of database: 156,788,448 effective search space: 32141631840 effective search space used: 32141631840 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 164 (68.3 bits)