BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0280 (rbsk) DE:RIBOKINASE (293 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||E75157 ribokinase PAB0280 - Pyrococcus abyssi (strain Orsay... 587 e-167 pir||G71196 probable ribokinase - Pyrococcus horikoshii >gi|3258... 473 e-132 pir||T44955 ribokinase (EC 2.7.1.15) [imported] - Pyrobaculum ae... 141 1e-32 pir||G72752 probable sugar kinase APE0012 - Aeropyrum pernix (st... 137 2e-31 pir||F69152 ribokinase - Methanobacterium thermoautotrophicum (s... 120 2e-26 emb|CAB75572.1| (AJ243655) hypothetical protein [Methanobacteriu... 116 4e-25 emb|CAB66287.1| (AL136519) carbohydrate kinase [Streptomyces coe... 109 3e-23 pir||C69113 ribokinase - Methanobacterium thermoautotrophicum (s... 109 5e-23 pir||B83403 ribokinase PA1950 [imported] - Pseudomonas aeruginos... 106 3e-22 gi|11497968 carbohydrate kinase, pfkB family [Archaeoglobus fulg... 103 2e-21 sp|O27587|YF44_METTH HYPOTHETICAL SUGAR KINASE MTH1544 >gi|74300... 100 2e-20 sp|P44331|RBSK_HAEIN RIBOKINASE >gi|1075217|pir||B64073 ribokina... 100 3e-20 dbj|BAB07447.1| (AP001519) ribokinase [Bacillus halodurans] 99 7e-20 pir||D75260 probable carbohydrate kinase - Deinococcus radiodura... 99 7e-20 gb|AAG20057.1| (AE005085) sugar kinase; Suk [Halobacterium sp. N... 99 7e-20 gb|AAK40370.1| Ribokinase (rbsK-1) [Sulfolobus solfataricus] 98 2e-19 pir||E72516 probable ribokinase APE2106 - Aeropyrum pernix (stra... 98 2e-19 pir||D82497 ribokinase VCA0131 [imported] - Vibrio cholerae (gro... 98 2e-19 pir||T20529 hypothetical protein F07A11.5 - Caenorhabditis elega... 94 1e-18 sp|P42414|IOLC_BACSU IOLC PROTEIN >gi|7475652|pir||C69645 myo-in... 93 4e-18 sp|O60116|RBSK_SCHPO PUTATIVE RIBOKINASE >gi|7493292|pir||T39594... 93 4e-18 dbj|BAB06038.1| (AP001515) myo-inositol catabolism [Bacillus hal... 92 6e-18 sp|Q57849|Y406_METJA HYPOTHETICAL SUGAR KINASE MJ0406 >gi|212924... 92 9e-18 pir||E72311 ribokinase - Thermotoga maritima (strain MSB8) >gi|4... 90 2e-17 emb|CAA04719.1| (AJ001389) RBSK [Rhizobium etli] 88 1e-16 gb|AAD50017.1|AC007651_12 (AC007651) Similar to ribokinase [Arab... 86 4e-16 pir||T07588 fructokinase (EC 2.7.1.4) 1 - tomato >gi|2102691|gb|... 85 7e-16 dbj|BAB11252.1| (AB010074) fructokinase 1 [Arabidopsis thaliana] 85 7e-16 dbj|BAB07443.1| (AP001519) 2-keto-3-deoxygluconate kinase [Bacil... 85 9e-16 gb|AAF35840.1|AF205034_3 (AF205034) ScrK [Clostridium acetobutyl... 82 6e-15 sp|P05054|RBSK_ECOLI RIBOKINASE >gi|66667|pir||KIECRB ribokinase... 82 8e-15 sp|O59128|YE59_PYRHO HYPOTHETICAL SUGAR KINASE PH1459 >gi|743422... 82 1e-14 dbj|BAB16906.1| (AP002863) contains ESTs AU029689(EE1266),C91697... 81 1e-14 pir||T01971 fructokinase (EC 2.7.1.4) - Arabidopsis thaliana >gi... 80 2e-14 gb|AAK42589.1| Ribokinase (rbsK-2) [Sulfolobus solfataricus] 80 3e-14 gb|AAF79436.1|AC025808_18 (AC025808) F18O14.35 [Arabidopsis thal... 78 1e-13 dbj|BAB05576.1| (AP001513) fructokinase [Bacillus halodurans] 77 2e-13 pir||T46874 ribokinase homolog [imported] - Sulfolobus solfatari... 77 3e-13 gb|AAC98130.1| (AF098273) 2-keto-3-deoxy-gluconate kinase [Bacil... 74 2e-12 pir||E75385 carbohydrate kinase, PfkB family - Deinococcus radio... 74 2e-12 pir||A75599 ribokinase - Deinococcus radiodurans (strain R1) >gi... 74 2e-12 gi|11545855 ribokinase [Homo sapiens] >gi|10799803|emb|CAC12877.... 74 2e-12 gb|AAG12908.1|AC020665_17 (AC020665) fructokinase, putative; 800... 73 3e-12 gb|AAF80125.1|AC024174_7 (AC024174) Contains similarity to a fru... 73 4e-12 pir||G75112 fructokinase (EC 2.7.1.4) PAB0482 - Pyrococcus abyss... 73 5e-12 sp|P40713|SCRK_ECOLI FRUCTOKINASE >gi|1073355|pir||S52161 probab... 72 9e-12 gb|AAF80126.1|AC024174_8 (AC024174) Contains similarity to a fru... 72 9e-12 sp|P36945|RBSK_BACSU RIBOKINASE >gi|7427979|pir||D69690 ribokina... 70 3e-11 pir||T49289 fructokinase-like protein - Arabidopsis thaliana >gi... 70 3e-11 gi|10383797 ribokinase; Rbk1p [Saccharomyces cerevisiae] 70 3e-11 sp|P25332|RBSK_YEAST PROBABLE RIBOKINASE >gi|279503|pir||KIBYRB ... 69 6e-11 pir||D64937 probable sugar kinase (EC 2.7.1.-) - Escherichia col... 69 6e-11 gb|AAB51108.1| (U62329) fructokinase [Lycopersicon esculentum] >... 69 6e-11 sp|P77493|YDJH_ECOLI HYPOTHETICAL SUGAR KINASE IN ANSA-GAPA INTE... 69 6e-11 pir||A82433 fructokinase VCA0656 [imported] - Vibrio cholerae (g... 69 6e-11 gb|AAK43293.1| Fructokinase [Sulfolobus solfataricus] 69 8e-11 sp|P37829|SCRK_SOLTU FRUCTOKINASE >gi|626018|pir||S39997 fructok... 69 8e-11 sp|O34768|YDJE_BACSU HYPOTHETICAL SUGAR KINASE IN GUTA-COTA INTE... 69 8e-11 pir||H72394 fructokinase - Thermotoga maritima (strain MSB8) >gi... 69 8e-11 pir||D75288 carbohydrate kinase, PfkB family - Deinococcus radio... 69 8e-11 >pir||E75157 ribokinase PAB0280 - Pyrococcus abyssi (strain Orsay) >gi|5457850|emb|CAB49340.1| (AJ248284) RIBOKINASE [Pyrococcus abyssi] Length = 293 Score = 587 bits (1497), Expect = e-167 Identities = 293/293 (100%), Positives = 293/293 (100%) Query: 1 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG 60 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG Sbjct: 1 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG 60 Query: 61 AVGNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKYPGANRWKEVNT 120 AVGNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKYPGANRWKEVNT Sbjct: 61 AVGNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKYPGANRWKEVNT 120 Query: 121 EYLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGEMEVPRDVEKELDILMMNEDEF 180 EYLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGEMEVPRDVEKELDILMMNEDEF Sbjct: 121 EYLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGEMEVPRDVEKELDILMMNEDEF 180 Query: 181 KAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGF 240 KAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGF Sbjct: 181 KAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGF 240 Query: 241 LYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQELKLNLPI 293 LYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQELKLNLPI Sbjct: 241 LYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQELKLNLPI 293 >pir||G71196 probable ribokinase - Pyrococcus horikoshii >gi|3258283|dbj|BAA30966.1| (AP000007) 296aa long hypothetical ribokinase [Pyrococcus horikoshii] Length = 296 Score = 473 bits (1203), Expect = e-132 Identities = 228/292 (78%), Positives = 263/292 (89%) Query: 1 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG 60 MR DVICMGNLNYDI F++E+FP HEKVNAK V+TGLGGSAGNTATWL+ LGLKVGFIG Sbjct: 1 MRLDVICMGNLNYDITFILERFPEFHEKVNAKEVYTGLGGSAGNTATWLSLLGLKVGFIG 60 Query: 61 AVGNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKYPGANRWKEVNT 120 +VGNDDFGRLHLEFF++IGVDT GIKVV++ TG+AV MV GEDKRIVKYPGANR+KEV Sbjct: 61 SVGNDDFGRLHLEFFKKIGVDTRGIKVVDEPTGVAVMMVIGEDKRIVKYPGANRFKEVRE 120 Query: 121 EYLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGEMEVPRDVEKELDILMMNEDEF 180 +YLK ARHLHLSSNP+ L+ +AV AK LGLTVSFDPGEMEVP+++E+++DILMMNEDEF Sbjct: 121 DYLKLARHLHLSSNPLSLVEKAVTLAKNLGLTVSFDPGEMEVPKNIEEKVDILMMNEDEF 180 Query: 181 KAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGF 240 K KYG L I VK+RIAIATLNGGGALVRD+ G+V+EVRGLSAKA+DTTGGGD+FNAGF Sbjct: 181 KRKYGDLKNITKVKSRIAIATLNGGGALVRDQNGKVYEVRGLSAKAVDTTGGGDSFNAGF 240 Query: 241 LYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQELKLNLP 292 +YGFL+GWDVV+SAKLGMLLAYLTVQ+VGARSAV PL+E+KK A EL L+LP Sbjct: 241 IYGFLNGWDVVSSAKLGMLLAYLTVQKVGARSAVIPLEEVKKKANELNLDLP 292 >pir||T44955 ribokinase (EC 2.7.1.15) [imported] - Pyrobaculum aerophilum >gi|4099074|gb|AAD00536.1| (U82374) ribokinase [Pyrobaculum aerophilum] Length = 305 Score = 141 bits (351), Expect = 1e-32 Identities = 99/301 (32%), Positives = 150/301 (48%), Gaps = 20/301 (6%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 V +GNLN+DI + + PG E V A ++TG GGSA N A +AK+GL FIGAVG Sbjct: 3 VASIGNLNFDIYLKVSELPGPDENVEALDLYTGGGGSAANFAVAIAKMGLSARFIGAVGE 62 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDA-TGIAVTMVKGED-KRIVKYPGANRW---KEVN 119 D G + L R GVD S +K V +G+ V +V + KR+V Y GAN ++ Sbjct: 63 DPLGEISLRELRAEGVDVSFVKRVRGVRSGVVVVLVHPDGVKRMVSYRGANLGLTPADLT 122 Query: 120 TEYLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGE------MEVPRDVEKELDIL 173 + +H+HL++ ELI +A E A+E+G ++S D G +E+ R + +D++ Sbjct: 123 VDKFAGVKHIHLATGRTELILKAKEIAREIGASISVDGGTALARKGLEIVRAAVEGVDVV 182 Query: 174 MMNEDEFKAKYGSLDR-------IKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKA 226 MN E + + D +++K + TL GA V + G + V A Sbjct: 183 FMNHVEAQLVANAGDHKSAVEKLARELKVGELVVTLGPIGA-VAFKNGRLLHVDAFKVNA 241 Query: 227 IDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQE 286 +DTTG GD F A ++ +L G D+ A + V AR++ R DE+ + Sbjct: 242 VDTTGAGDCFAAAYITMYLRGRDLYERLLFANAAAAIKVTRPSARASPR-YDEVVAFLES 300 Query: 287 L 287 L Sbjct: 301 L 301 >pir||G72752 probable sugar kinase APE0012 - Aeropyrum pernix (strain K1) >gi|5103400|dbj|BAA78921.1| (AP000058) 310aa long hypothetical sugar kinase [Aeropyrum pernix] Length = 310 Score = 137 bits (341), Expect = 2e-31 Identities = 89/303 (29%), Positives = 160/303 (52%), Gaps = 18/303 (5%) Query: 6 ICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGND 65 + +G+ D+ +E+ PG+ E+ K +GGSA N A L +LG++ G IG +G D Sbjct: 9 VAVGHALVDLRLYVERIPGVDEEAVIKDETRSVGGSAANVAVVLRRLGVQSGIIGKIGLD 68 Query: 66 DFGRLHLEFFREIGVDTSGIKV-VNDATGIAVTMVKGEDK-RIVKYPGANRW---KEVNT 120 DFGR+ ++ GVD SG++V + D TG +V + E I + GA E++ Sbjct: 69 DFGRIAVDNLMREGVDISGLRVSLRDRTGFSVVVRDKEGSITIYSFKGAAEKLEPGEIDA 128 Query: 121 EYLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGEM------EVPRDVEKELDILM 174 + + R++H+H++S + + VE AK+ +TVS+DPG + E ++ ++DI+ Sbjct: 129 DAIGRSKHVHVASLRPDTTLKTVEIAKKRSITVSWDPGRVLSKMGAERLANIISKVDIIF 188 Query: 175 MNEDEFKAKYGSLD------RIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAID 228 +N +E K G D +K + +I + L G+ + GEV + +D Sbjct: 189 VNRNEAKNLTGYHDYRQAARHLKKLGPKIVVIKLGASGSYILYSDGEVFVPAIKPERVVD 248 Query: 229 TTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQELK 288 TTG GD++ AGF+ G L G+ + ++ ++A + V +G+ +A +E+ + A+EL Sbjct: 249 TTGAGDSYAAGFIAGLLRGYTIEKASLYATIVASIKVSRLGSNAAPSH-EEVVEKARELG 307 Query: 289 LNL 291 + + Sbjct: 308 VEI 310 >pir||F69152 ribokinase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621467|gb|AAB84910.1| (AE000825) ribokinase [Methanobacterium thermoautotrophicum] Length = 298 Score = 120 bits (299), Expect = 2e-26 Identities = 94/287 (32%), Positives = 137/287 (46%), Gaps = 14/287 (4%) Query: 1 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG 60 MRFD + +G LN D + ++E+ G E+ +G+ GGSA NT L++LGL+ IG Sbjct: 1 MRFDAVGLGALNMDQLHMVERIAGPDEETFVRGLVESCGGSAANTMIGLSRLGLRTAHIG 60 Query: 61 AVGNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKY-PGAN---RWK 116 V +D G L GV + +G + V + R + PG N R Sbjct: 61 KVADDREGGLLRSNLSSEGVTDFTVVADTGRSGRVMGFVDPDGNRALYVDPGVNDTLRVD 120 Query: 117 EVNTEYLKRARHLHLSSNPIELIREAVE--KAKELGLTVSFDPGEMEVPR------DVEK 168 EV E L LHL+S + I VE +A + +TVS DPG + R D+ + Sbjct: 121 EVADEAL-NTELLHLTSFAGDGINVQVEVIEALDESVTVSLDPGHIYASRGVSELSDILE 179 Query: 169 ELDILMMNEDEFKAKYGSLDRIKDVK-ARIAIATLNGGGALVRDEKGEVHEVRGLSAKAI 227 DIL+ N+ E + GS D + I + + G VR GE V LS + + Sbjct: 180 RTDILLTNQRELELMTGSADPEEAASLLGIGVVVVKMGARGVRAWDGESVMVDALSTECV 239 Query: 228 DTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAV 274 DTTG GDAFNAGF+Y +L G+ + S + G +A + GA ++ Sbjct: 240 DTTGAGDAFNAGFIYAWLEGFGLEVSCRFGNYIASRCIGGYGATESL 286 >emb|CAB75572.1| (AJ243655) hypothetical protein [Methanobacterium thermoautotrophicum] Length = 312 Score = 116 bits (287), Expect = 4e-25 Identities = 94/288 (32%), Positives = 135/288 (46%), Gaps = 16/288 (5%) Query: 1 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG 60 M FD + +G LN D + ++E+ G E+V + + GGSA NT LA+LGL+ FIG Sbjct: 1 MLFDAVGLGALNMDQLHMVERIAGPDEEVFVRSILESCGGSAANTIIGLARLGLRTAFIG 60 Query: 61 AVGNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKY-PGAN---RWK 116 V D G + E + GV +G + V + R + PG N Sbjct: 61 KVAGDREGSILRENLKGGGVADYVAVSDEGRSGRVMGFVDPQGNRALYVDPGVNDTLSMD 120 Query: 117 EVNTEYLKRARHLHLSS---NPIELIREAVEKAKELGLTVSFDPGEMEVPR------DVE 167 EV E LK R LHL+S + I + RE + + +TVS DPG + R + Sbjct: 121 EVREEALK-TRLLHLTSFAGSGIRVQREVLGVIDD-SVTVSLDPGHLYAERGASELEGIL 178 Query: 168 KELDILMMNEDEFKAKYGSLD-RIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKA 226 + DIL++N E + GS D + + + + + G VR G V L Sbjct: 179 ERTDILLVNRRELEILTGSPDPAMASAELGVDVVVMKMGSEGVRAFDGSEVMVEALETSC 238 Query: 227 IDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAV 274 DTTG GDAFNAGFLY +LSG + S G +A ++ GA S++ Sbjct: 239 RDTTGAGDAFNAGFLYAWLSGHGLEVSCLFGNYMASRCIEGYGATSSL 286 >emb|CAB66287.1| (AL136519) carbohydrate kinase [Streptomyces coelicolor A3(2)] Length = 306 Score = 109 bits (271), Expect = 3e-23 Identities = 87/289 (30%), Positives = 129/289 (44%), Gaps = 19/289 (6%) Query: 3 FDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAV 62 +D++ +G+ N D+V +E+ P E V + GG GN A A+LG + + V Sbjct: 4 YDLLVVGSANADLVIGVERRPAAGETVLGSDLAVHPGGKGGNQAVAAARLGARTALLARV 63 Query: 63 GNDDFGRLHLEFFREIGVDTSGIKVVNDATGIA-VTMVKGEDKRIVKYPGANRWKEVNTE 121 G+DD+GRL L+ R GVDT G+ V TG+A +T+ D IV PGAN + + Sbjct: 64 GDDDYGRLLLDSQRAAGVDTVGVLVGGAPTGVALITVDPSGDNSIVVSPGAN-GRLAPGD 122 Query: 122 YLKRARHLHLS-------SNPIELIREAVEKAKELGLTVSFDPGEMEVPRDVEKELDILM 174 A H S P+E + E V V +P++V D L+ Sbjct: 123 VRAAASLFHASRVVSTQLEIPLETVVEVVRSLAPDSRFVLNPSPPRPLPQEVLTACDPLI 182 Query: 175 MNEDEFKAKYGSL---DRIKD-------VKARIAIATLNGGGALVRDEKGEVHEVRGLSA 224 +NE E K G +R +D R + TL GALV G V V + Sbjct: 183 VNEHEAKVILGDSLVGERPEDWARVLLAKGPRSVVVTLGAEGALVASAAGGVVRVPSVKV 242 Query: 225 KAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSA 273 A+DTTG GDAF A + +G + ++A + V + GA+ + Sbjct: 243 DAVDTTGAGDAFTAALAWRLGTGESLADAAAYAARVGAAAVTKAGAQES 291 >pir||C69113 ribokinase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622976|gb|AAB86307.1| (AE000937) ribokinase [Methanobacterium thermoautotrophicum] Length = 278 Score = 109 bits (269), Expect = 5e-23 Identities = 82/280 (29%), Positives = 129/280 (45%), Gaps = 20/280 (7%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 V+ +G N D +F +++F ++ + GGSA N A W++ LG + A G Sbjct: 4 VVSVGTCNMDFIFRVQEFVEPDSEMYIDDIHILPGGSALNFAVWISALGFSSDIVAATGG 63 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKR-IVKYPGANRWKEVNT--- 120 D +G + GV T + VV TG+A V G +R I Y GAN E+ T Sbjct: 64 DMYGEIIRSRLESEGVSTGCLSVVEKPTGMAFISVDGSGRRSIYSYMGANAELEIGTPEG 123 Query: 121 EYLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGE------MEVPRDVEKELDILM 174 ++ A +HLS +E+ + E + V F PG ++V V ++ ++L Sbjct: 124 RCIRAADAVHLSGCYVEVAQRVAEIRE-----VYFSPGRLLAGYGLDVLEPVLRKTEVLF 178 Query: 175 MNEDEFKAKYGS----LDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTT 230 +N+DE + GS + R+ V + T GGA + E++ A AIDTT Sbjct: 179 LNDDELEILTGSRKSGISRLLGVGVDYVVVTHGPGGASFFSADHSL-EMKVEDAGAIDTT 237 Query: 231 GGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGA 270 G GDAF AGF+ +L G++ + + G A + GA Sbjct: 238 GAGDAFAAGFMSEWLRGYEPLECLRGGHRAALKVISRFGA 277 >pir||B83403 ribokinase PA1950 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9947947|gb|AAG05338.1|AE004621_9 (AE004621) ribokinase [Pseudomonas aeruginosa] Length = 308 Score = 106 bits (263), Expect = 3e-22 Identities = 83/307 (27%), Positives = 141/307 (45%), Gaps = 30/307 (9%) Query: 1 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG 60 M+ V+ +G+LN D+V + P E + + T GG N A A+LG +V IG Sbjct: 1 MQAKVLVVGSLNMDLVVRAPRLPRGGETLAGQSFITVPGGKGANQAVAAARLGAEVAMIG 60 Query: 61 AVGNDDFGRLHLEFFREIGVDTSGI-KVVNDATGIAVTMVKGEDKR-IVKYPGANRWKEV 118 +G+D +G + G+D G+ +V +++G+A+ +V + IV G N Sbjct: 61 CLGDDAYGDQLYRALQAEGIDCQGVERVAGESSGVALIVVDDSSQNAIVIVAGGNG---- 116 Query: 119 NTEYLKRARHLHL----------SSNPIELIREAVEKAKELGLTVSFD--PGEMEVPRDV 166 + ARH HL +P+E + + +A LG TV + P +VP + Sbjct: 117 HLSPAVLARHEHLLEQAQVVVCQLESPLETVGHVLRRAHALGKTVILNPAPATRDVPAEW 176 Query: 167 EKELDILMMNE-----------DEFKAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGE 215 +D L+ NE D ++ + +R++++ A I TL GAL+ E G Sbjct: 177 LPLVDYLVPNETESELLCRLPVDSLESAGRAAERLREMGAGRVIVTLGAQGALLVGE-GR 235 Query: 216 VHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVR 275 V KA+DTT GD F GF G D + + G A ++V +GA++++ Sbjct: 236 VEHFPVARVKALDTTAAGDTFVGGFAAALARGLDEAAAIRFGQAAAAISVTRLGAQTSIP 295 Query: 276 PLDEIKK 282 +E+++ Sbjct: 296 SREEVER 302 >gi|11497968 carbohydrate kinase, pfkB family [Archaeoglobus fulgidus] >gi|3915361|sp|O29891|Y356_ARCFU HYPOTHETICAL SUGAR KINASE AF0356 >gi|7430035|pir||D69294 carbohydrate kinase, pfkB family homolog - Archaeoglobus fulgidus >gi|2650279|gb|AAB90880.1| (AE001080) carbohydrate kinase, pfkB family [Archaeoglobus fulgidus] Length = 250 Score = 103 bits (255), Expect = 2e-21 Identities = 76/245 (31%), Positives = 123/245 (50%), Gaps = 21/245 (8%) Query: 49 LAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKR-IV 107 L++LG++ +IG VG+D+ GR+ L F GV T + +G A+ V + R I+ Sbjct: 3 LSRLGIETAYIGKVGSDEEGRILLADFEREGVSTDFVIRAEGRSGTAMIFVDEKGNRAIL 62 Query: 108 KYPGAN---RWKEVNTEYLKRARHLHLSS----NPIELIREAVEKAKELGLTVSFDPGEM 160 PG N + E++ + ++ +HL+S N ++ + +E +VSFDPG Sbjct: 63 VDPGVNDTIAYDEIDVDSARKYDLIHLTSFICKNGLDSLNSQKRIVEEFD-SVSFDPGMP 121 Query: 161 EVPR---DVEKELD---ILMMNEDEFKAKYG-----SLDRIKDVKARIAIATLNGGGALV 209 R D+EK L I + N E + + + +R ++ I L G + Sbjct: 122 YAERGLGDMEKILKNTTIFLPNRQEIEMLFSEDYRTAAERCIEMGIEIVAVKLGSEGCWI 181 Query: 210 RDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVG 269 + EV V+ +S K +DTTG GDAFNAGFLYG+L G D+ +LG +A +++ G Sbjct: 182 KKGDREV-TVKPVSTKVVDTTGAGDAFNAGFLYGYLKGKDIEECGRLGNFVAAKCIEKYG 240 Query: 270 ARSAV 274 AR + Sbjct: 241 AREGL 245 >sp|O27587|YF44_METTH HYPOTHETICAL SUGAR KINASE MTH1544 >gi|7430033|pir||A69073 ribokinase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622665|gb|AAB86018.1| (AE000915) ribokinase [Methanobacterium thermoautotrophicum] Length = 309 Score = 100 bits (246), Expect = 2e-20 Identities = 76/294 (25%), Positives = 139/294 (46%), Gaps = 17/294 (5%) Query: 4 DVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVG 63 D++ +G+ +D + +++FP + K + GG+A N A ++LGL+ + AVG Sbjct: 6 DLLAVGHTAFDYIIHLDEFPEPNTSTAIKRMRNLHGGAAANVALVGSRLGLRTSLVSAVG 65 Query: 64 NDDFGRLHLEFFREIGVD-TSGIKVVNDATGIAVTMVKGEDKRI-VKYPGANRW---KEV 118 D G + E G+D S I V +++T A M + +I Y GA R+ E Sbjct: 66 GDFEGSEYRELLESSGIDIESMILVADESTPTAFVMTDSDHNQISYFYWGAARYFKDAET 125 Query: 119 NTEYLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGE---MEVPRDVEKEL---DI 172 + +K AR +HL++ E A+ LG +SFDPG+ M +E+ + DI Sbjct: 126 PADAIKSARAVHLATGDPSFNCRCGEFARSLGKIISFDPGQDLHMYSRSQLERAVGVCDI 185 Query: 173 LMMNEDEFKAKYGSLD----RIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAID 228 L N E L ++++ + + T G+++ + +V ++ + +A+D Sbjct: 186 LFGNHHEIDRICSKLSVDIHGLREMGPGVVVKTYGKEGSIIYSD--DVIKIDAIPREAVD 243 Query: 229 TTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKK 282 TG GD++ AGF+ +L G D+ + +A V++ G ++ + E K Sbjct: 244 PTGAGDSYRAGFMRAYLRGADLKTCGRFASAVASFIVEDEGTQTNIPDTGEAVK 297 >sp|P44331|RBSK_HAEIN RIBOKINASE >gi|1075217|pir||B64073 ribokinase (EC 2.7.1.15) - Haemophilus influenzae (strain Rd KW20) >gi|1573486|gb|AAC22163.1| (U32732) ribokinase (rbsK) [Haemophilus influenzae Rd] Length = 306 Score = 99.8 bits (245), Expect = 3e-20 Identities = 81/294 (27%), Positives = 131/294 (44%), Gaps = 21/294 (7%) Query: 1 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG 60 MR + +G++N D V + F E + + GG N A A+LG KV FI Sbjct: 1 MRKTLTVLGSINADHVISVPYFTKPGETLTGQNYQIAYGGKGANQAVAAARLGAKVAFIS 60 Query: 61 AVGNDDFGRLHLEFFREIGVDTSGIKVVN-DATGIA-VTMVKGEDKRIVKYPGANRW--- 115 +G+D G+ F + G+DT+ I V+ + TG+A + + K + IV GAN Sbjct: 61 CIGSDSIGKTMKNAFAQEGIDTTHINTVSQEMTGMAFIQVAKSSENSIVLASGANSHLSE 120 Query: 116 ---KEVNTEYLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGEMEVPRD-VEKELD 171 ++ + + L P+ + A + AK+ G+ V +P ++ D + +D Sbjct: 121 MVVRQSEAQIAQSDCLLMQLETPLSGVELAAQIAKKNGVKVVLNPAPAQILSDELLSLID 180 Query: 172 ILMMNEDEFKAKYG--SLDRIKDVKA---------RIAIATLNGGGALVRDEKGEVHEVR 220 I+ NE E + G D VKA + TL G V KG+ ++ Sbjct: 181 IITPNETEAEILTGVEVADEQSAVKAASVFHDKGIETVMITLGAKGVFV-SRKGKSRIIK 239 Query: 221 GLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAV 274 G +AIDTT GD FN GF+ L + + G A ++V + GA+S++ Sbjct: 240 GFCVQAIDTTAAGDTFNGGFVTALLEEKSFDEAIRFGQAAAAISVTKKGAQSSI 293 >dbj|BAB07447.1| (AP001519) ribokinase [Bacillus halodurans] Length = 294 Score = 98.7 bits (242), Expect = 7e-20 Identities = 78/293 (26%), Positives = 126/293 (42%), Gaps = 16/293 (5%) Query: 4 DVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVG 63 ++ +G++N D+V + + P E V K T GG N A A+LG V IG VG Sbjct: 5 NITVVGSINMDMVTITDVVPVQGETVLGKDFRTVPGGKGANQAVAAARLGANVRMIGRVG 64 Query: 64 NDDFGRLHLEFFREIGVDTSGIKVVNDAT-GIAVTMVKGEDKRIVKYPGANRWKEVNTEY 122 +D FG + E + G+ T +K V D T G+A ++ D RI+ GAN + V +Y Sbjct: 65 DDPFGHVLTENLAKEGIITDSVKPVTDCTSGVATILLSDRDNRIIVTKGAN--EHVTPDY 122 Query: 123 LKRARHLHLSSN--------PIELIREAVEKAKELGLTVSFDPG-EMEVPRDVEKELDIL 173 + +S+ P+E + +E + +T +P ++P + + Sbjct: 123 VAAFEQELAASDVVLLQLEIPLETVAYVLEFCAKHHVTTVLNPAPAQKLPDAAWTDATYI 182 Query: 174 MMNEDEFKAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGG 233 NE+E +G D R + G + E E +V + +DTTG G Sbjct: 183 SPNENECLQLFGD---EPDANLRQKLIMTKGADGVQFYENDEQVQVESFRVEPVDTTGAG 239 Query: 234 DAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQE 286 D FN F L G V + + A L+VQ GA+ + +++ QE Sbjct: 240 DTFNGAFAVA-LGGGTVKEAVRFANAAAALSVQSFGAQGGMPTKAQVQSFLQE 291 >pir||D75260 probable carbohydrate kinase - Deinococcus radiodurans (strain R1) >gi|6460378|gb|AAF12093.1|AE002084_6 (AE002084) carbohydrate kinase, putative [Deinococcus radiodurans] Length = 343 Score = 98.7 bits (242), Expect = 7e-20 Identities = 75/266 (28%), Positives = 115/266 (43%), Gaps = 29/266 (10%) Query: 39 GGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTM 98 GGSA N A W A+LG F+G +G D FG L R GV + TG+ + + Sbjct: 46 GGSAANLAVWAARLGAPTTFVGKIGQDRFGELATAELRAEGVRAEVLASAAHPTGVILAL 105 Query: 99 VKGEDKRIVKYPGANRW----KEVNTEYLKRARHLHLSS------NPIELIREAVEKAKE 148 + +R + W +E+ + L A HLHL++ P EA AK Sbjct: 106 IDRRGQRAMLTGQGADWELLPEELPRDVLSSAGHLHLTAWSLFRDPPRAAALEAARIAKA 165 Query: 149 LGLTVSFDPGEMEVPRDVEKE----------LDILMMNEDEFKAKYGSLD--------RI 190 G T+S DPG ++ + + +E D++ N+DE +A G D R Sbjct: 166 GGATLSLDPGSFQMIQQLGREAFLNIVDALPFDVMFPNDDEARAMSGERDNEAALTWLRA 225 Query: 191 KDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDV 250 + +A IA+ ++ GAL+ + +V +D TG GDAF FL +L D Sbjct: 226 RYPRALIAL-KMDEDGALIEGPQTARVQVPATRDPLVDATGAGDAFGGAFLSQWLRHHDA 284 Query: 251 VNSAKLGMLLAYLTVQEVGARSAVRP 276 +A++ + + V GAR P Sbjct: 285 ERAARVAVQVGGWVVSRFGARPPADP 310 >gb|AAG20057.1| (AE005085) sugar kinase; Suk [Halobacterium sp. NRC-1] Length = 295 Score = 98.7 bits (242), Expect = 7e-20 Identities = 87/284 (30%), Positives = 125/284 (43%), Gaps = 21/284 (7%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 V+ G++N+D+ ++ P + GGSA N A LA + G +G+VG+ Sbjct: 4 VVAAGHVNWDVTLRVDALPEPDGEAEIVSQRRSGGGSAANVACALAGFDIDAGLVGSVGD 63 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVND-ATGIAVTMVKGE-DKRIVKYPGANRWKEVNTEY 122 D+ G L + GVD +G++VV+ T + +V + ++ GAN + V Sbjct: 64 DEHGLLAQRELQAAGVDLAGLRVVDGLETSVKYLLVDSRGEVMVLGNDGAN--EAVAPGD 121 Query: 123 LKRA------RHLHLSSNPIELIREAVEKAKELGLTVSFDPGEMEVPRDVEKEL---DIL 173 L A H+HL+S A+E TVSFDPG RD L DIL Sbjct: 122 LDPAVVGADCEHVHLTSQRPATAARLTALAREHDATVSFDPGRRLRDRDYGDALARTDIL 181 Query: 174 MMNEDEFKAKYGSLDRIKDVKA----RIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDT 229 +N++E A LD A R+ + GA V G V G + +DT Sbjct: 182 FVNDNEAGA---VLDDDGGPTAPDSDRVVVVKHGSEGATVHTPSGSVTH-PGFAVDPVDT 237 Query: 230 TGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSA 273 TG GDAF AGF+ L G D + + G L Q GAR+A Sbjct: 238 TGAGDAFAAGFVAVVLDGGDHERALEFGNACGALAAQHEGARTA 281 >gb|AAK40370.1| Ribokinase (rbsK-1) [Sulfolobus solfataricus] Length = 293 Score = 97.5 bits (239), Expect = 2e-19 Identities = 88/296 (29%), Positives = 138/296 (45%), Gaps = 20/296 (6%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 +I +G+ N D++ + K P I E V A ++ GG N A ++LG V I AVG+ Sbjct: 2 IIVVGSYNVDVILKVNKIPEIGETVIADELYITHGGKGSNQAVSASRLGSHVKIIVAVGD 61 Query: 65 DDFGRLHLEFFREIGVDTSGIKV---VNDATGIAVTMVKGEDKRIVKYPGANRWKEVNTE 121 D G +EF++ +D S +KV +N T KG + IV GAN + ++ + Sbjct: 62 DKHGTDAIEFWKSENIDVSKVKVKSGINTGTAYIFVDKKGRN-IIVVNRGANYY--LSED 118 Query: 122 YLKRARHLHLSSNPIELIREAVEK--AKELGLTVSFDPGEMEV-PRDVEKELDILMMNED 178 L + + +E IRE+V K AKE +P + ++ +DI+ NE Sbjct: 119 DLNNSLEGDILLMQLE-IRESVVKKAAKEFNGIKILNPAPANLKDTEILSLVDIITPNEI 177 Query: 179 EFKA-------KYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTG 231 EFK +YG +K VK + I TL GAL+ G+ + ID TG Sbjct: 178 EFKELVNTDDFEYGLNLLLKKVK-KAVIVTLGERGALLATRDGKKVLIPAPKVNVIDETG 236 Query: 232 GGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQEL 287 GD FNA G+D+ + + +A L+V ++GA LDE+ + +E+ Sbjct: 237 AGDVFNAALSVYLEKGYDLETAVEYANKVAALSVTKIGALGP--KLDEVVRFLEEI 290 >pir||E72516 probable ribokinase APE2106 - Aeropyrum pernix (strain K1) >gi|5105805|dbj|BAA81117.1| (AP000063) 313aa long hypothetical ribokinase [Aeropyrum pernix] Length = 313 Score = 97.5 bits (239), Expect = 2e-19 Identities = 81/270 (30%), Positives = 127/270 (47%), Gaps = 22/270 (8%) Query: 6 ICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGND 65 I +GN+N DI +++ PG E V A+ + G+GG+A N A +A+LG K + G + Sbjct: 12 IAVGNINLDISLSVDRLPGPEEVVFARDAWIGVGGAATNYAIAVAQLGQKPVLVAVAGRE 71 Query: 66 DFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGED--KRIVKYPGANR--WKEVNTE 121 ++ R GVD S +K V+ +G+ V MV D + +V GAN K + E Sbjct: 72 MERLGVVDTLRRRGVDVSRVKTVDRPSGVVVVMVVASDSHRSMVSMRGANEELLKYIEEE 131 Query: 122 YLKRAR---HLHLSSNPIELIREAVEKAKELGLTVSFDPG--EMEVPRDVEKEL---DIL 173 L H+H++S P + + A G T+S+DPG + P+ + L D + Sbjct: 132 PLDGVSGECHVHMASVPPQALDFAPG-----GCTLSYDPGGEAFKRPKSLWSRLPRVDWM 186 Query: 174 MMNEDEFKAKYGSLD-----RIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAID 228 +N E K GS D R+ + + + GGA V + V R + +D Sbjct: 187 FINTPELKGMSGSGDLAAAYRLLESGLKRLVLKHGRGGATVVERGFCVTLDRTPVLEPVD 246 Query: 229 TTGGGDAFNAGFLYGFLSGWDVVNSAKLGM 258 TG GDAF+A F +GW V + +L + Sbjct: 247 VTGAGDAFDAAFNIAVKAGWSVEEALRLAV 276 >pir||D82497 ribokinase VCA0131 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657519|gb|AAF96045.1| (AE004354) ribokinase [Vibrio cholerae] Length = 306 Score = 97.5 bits (239), Expect = 2e-19 Identities = 79/302 (26%), Positives = 135/302 (44%), Gaps = 21/302 (6%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 ++ +G++N D V + FP E ++ + GG N A A++ VGFI VG+ Sbjct: 4 LVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGD 63 Query: 65 DDFGRLHLEFFREIGVDTSGIKV-VNDATGIAVTMVKGEDKRIVKYPGANRWK------E 117 D FG E F+ G++T+G+K+ N TGIA+ V + + K E Sbjct: 64 DSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIE 123 Query: 118 VNTEYLKRARHLHLS-SNPIELIREAVEKAKELGLTVSFDPG-EMEVPRDVEKELDILMM 175 + ++ AR+L + P++ I +A ++AK V +P E+P ++ K +D++ Sbjct: 124 PDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITP 183 Query: 176 NEDEFKAKYG-----------SLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSA 224 NE E + G + D + I I TL G + + G + G Sbjct: 184 NETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWL-SQNGRGQRIPGFVV 242 Query: 225 KAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIA 284 KA DTT GD FN + G L + ++ K A ++V GA++++ E++ Sbjct: 243 KATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFL 302 Query: 285 QE 286 E Sbjct: 303 AE 304 >pir||T20529 hypothetical protein F07A11.5 - Caenorhabditis elegans >gi|3875535|emb|CAA91318.1| (Z66511) contains similarity to Pfam domain: PF00294 (pfkB family carbohydrate kinase), Score=164.6, E-value=3.4e-51, N=1~cDNA EST yk71c2.5 comes from this gene~cDNA EST yk71c2.3 comes from this gene~cDNA EST yk280h9.3 comes from this gene~cDNA EST yk2> Length = 343 Score = 94.4 bits (231), Expect = 1e-18 Identities = 84/301 (27%), Positives = 137/301 (44%), Gaps = 24/301 (7%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 ++ G++ D+V + FP E V G GG N A A+LG+ V IG VG Sbjct: 37 IVVFGSIVQDLVSYTDSFPRPGESVRGHNFKLGSGGKGANQAVAAARLGINVSMIGMVGE 96 Query: 65 DDFGRLHLEFFREIGVDTSGI---KVVNDATGIAVTMVKGEDKRIVKYPGAN-----RWK 116 D FG +++ GVDTS + K + AT +T+ K + IV GAN Sbjct: 97 DMFGDSNIKDLSSNGVDTSCVGRTKKTHTATA-TITVNKEGENNIVVTLGANLEMSPEIA 155 Query: 117 EVNTEYLKRARHLHLSSNPIEL-IREAVEKAKELGLTVSFD--PGEMEVPRDVEKELDIL 173 + N+ + ++ + E R A E A+ G+T + PG+ + + + + +DI+ Sbjct: 156 DANSSKIAGSKMVICQGEIDEKGNRRAFEIARSHGVTTFLNPAPGDPNMDKTILELVDII 215 Query: 174 MMNEDEFKAKYG-SLDRIKDVK----------ARIAIATLNGGGALVRDE-KGEVHEVRG 221 NE+E + G + + +KD + + AI TL G G L+ + +V Sbjct: 216 CTNENEAEFITGIAQNNVKDAEKAARAMLKMGPQHAIITLGGKGVLLASKGVDDVEHTAV 275 Query: 222 LSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIK 281 + A+DTTG GD F ++G + S + LA L+V G +S+ LDEI+ Sbjct: 276 IKVDAVDTTGAGDCFCGSLAAHLVAGHPISASIRSAANLAALSVTRHGTQSSYWKLDEIR 335 Query: 282 K 282 + Sbjct: 336 Q 336 >sp|P42414|IOLC_BACSU IOLC PROTEIN >gi|7475652|pir||C69645 myo-inositol catabolism iolC - Bacillus subtilis >gi|709983|dbj|BAA03292.1| (D14399) hypothetical protein [Bacillus subtilis] >gi|2636520|emb|CAB16010.1| (Z99124) alternate gene name: yxdC~myo-inositol catabolism [Bacillus subtilis] Length = 325 Score = 92.8 bits (227), Expect = 4e-18 Identities = 83/316 (26%), Positives = 146/316 (45%), Gaps = 37/316 (11%) Query: 3 FDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAV 62 FD++ +G D+ + P +K V GGS N A AKLGLK GFIG + Sbjct: 11 FDIVAIGRACIDLNAVEYNRPMEETMTFSKYV----GGSPANIAIGSAKLGLKAGFIGKI 66 Query: 63 GNDDFGRLHLEFFREIGVDTSGIKVVNDA--TGIAVT-MVKGEDKRIVKYPG--ANRW-- 115 +D GR + R+ GVDT+ + V D G+A T ++ E+ I+ Y A+ + Sbjct: 67 PDDQHGRFIESYMRKTGVDTTQMIVDQDGHKAGLAFTEILSPEECSILMYRDDVADLYLE 126 Query: 116 -KEVNTEYLKRARHLHLSSNPI------ELIREAVEKAKELGLTVSFD----PGEMEVPR 164 EV+ +Y+ A+ L +S + E + +AV+ AK+ + V F+ P + Sbjct: 127 PSEVSEDYIANAKMLLVSGTALAKSPSREAVLKAVQYAKKHQVKVVFELDYRPYTWQSSD 186 Query: 165 D-------VEKELDILMMNEDEFK--------AKYGSLDRIKDVKARIAIATLNGGGALV 209 + V ++ DI++ DEF + S++ + A + + G+ Sbjct: 187 ETAVYYSLVAEQSDIVIGTRDEFDVMENRTGGSNEESVNHLFGHSADLVVIKHGVEGSYA 246 Query: 210 RDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVG 269 + GEV + K + T G GD++ + F+YG +SG D+ + K G A + V + Sbjct: 247 YSKSGEVFRAQAYKTKVLKTFGAGDSYASAFIYGLVSGKDIETALKYGSASASIVVSKHS 306 Query: 270 ARSAVRPLDEIKKIAQ 285 + A+ +EI+++ + Sbjct: 307 SSEAMPTAEEIEQLIE 322 >sp|O60116|RBSK_SCHPO PUTATIVE RIBOKINASE >gi|7493292|pir||T39594 ribokinase - fission yeast (Schizosaccharomyces pombe) >gi|3133096|emb|CAA19022.1| (AL023554) ribokinase; pfkB family carbohydrate kinase [Schizosaccharomyces pombe] Length = 318 Score = 92.8 bits (227), Expect = 4e-18 Identities = 83/308 (26%), Positives = 139/308 (44%), Gaps = 33/308 (10%) Query: 4 DVICMGNLNYDIVFLMEKFPGIHEKVNAK--GVFTGLGGSAGNTATWLAKLG----LKVG 57 +++ +G++N D+V + P E ++ + G TG GG N A +A+L KV Sbjct: 3 NIVVLGSMNTDLVMRTKICPSGGETIHGEPDGFSTGNGGKGANQAVAVARLSNPADTKVS 62 Query: 58 FIGAVGNDDFGRLHLEFFREIGVDTSGIKVV-NDATGIAVTMVKGE-DKRIVKYPGANRW 115 +G VG+D FG L ++ GV+ +K + N +TG+A+ +V+ + RI+ GAN Sbjct: 63 MLGCVGDDAFGVEMLSGLKKDGVNVDNVKKIENKSTGVAMIIVEETGENRILLSEGANG- 121 Query: 116 KEVNTEYLKRARHLHLSSN--------PIELIREAVEKAKELGLTVSFDPGE-MEVPRDV 166 V+T ++K + N P+E + A++ A + G+ V +P + + D+ Sbjct: 122 -NVDTAFVKAMEQRISTCNLLIMQLEIPLEAVEIALQIAHKHGVDVLMNPAPAIPLSHDM 180 Query: 167 EKELDILMMNEDEFKAKYGSLDR---IKDVKA-----------RIAIATLNGGGALVRDE 212 L+ NE E D +++V A + I TL GA + Sbjct: 181 ISYCAYLVPNEHEAAILLNQADSPATLENVDAYASKLLSFGVRKAVIITLGSQGAYYKSA 240 Query: 213 KGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARS 272 GE V KA+DTT GD F F G + +S + + +TVQ GA S Sbjct: 241 NGESALVSACKVKAVDTTAAGDTFIGAFSNSIAHGQPLKDSLEFAAKCSAITVQRKGAAS 300 Query: 273 AVRPLDEI 280 ++ L E+ Sbjct: 301 SIPSLLEV 308 >dbj|BAB06038.1| (AP001515) myo-inositol catabolism [Bacillus halodurans] Length = 331 Score = 92.4 bits (226), Expect = 6e-18 Identities = 83/318 (26%), Positives = 144/318 (45%), Gaps = 38/318 (11%) Query: 3 FDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAV 62 FD+I +G D+ + P +K V GGS N +KLGLK GFIG + Sbjct: 11 FDLIAIGRACIDLNAVEYNRPMEETMTFSKYV----GGSPANIVIGSSKLGLKAGFIGKI 66 Query: 63 GNDDFGRLHLEFFREIGVDTSGIKVVNDA--TGIAVTMVKG-EDKRIVKY--PGANRW-- 115 +D GR + R +GVDTS + V + TG+A T +K E+ I+ Y A+ + Sbjct: 67 ADDQHGRFIESYMRGVGVDTSNLVVDQEGHKTGLAFTEIKSPEECSILMYRQDVADLYLS 126 Query: 116 -KEVNTEYLKRARHLHLSSNPI------ELIREAVEKAKELGLTVSFD----PGEMEVPR 164 +EVN Y++R++ L +S + E + +A+ AK + V F+ P E P Sbjct: 127 PEEVNEAYIRRSKLLLVSGTALSKSPSREAVLKAIRLAKRNDVKVVFELDYRPYSWETPE 186 Query: 165 D-------VEKELDILMMNEDEF-----KAKYGSLDR----IKDVKARIAIATLNGGGAL 208 + V ++ DI++ +EF + + G D + + + G+ Sbjct: 187 ETAVYYSLVAEQSDIVIGTREEFDVLENRTEKGDNDETIRYLFKHSPELIVIKHGVEGSF 246 Query: 209 VRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEV 268 + GE + K + T G GD++ + FLY +SG + + K G A + V + Sbjct: 247 AYTKAGEAYRGYAYKTKVLKTFGAGDSYASAFLYALISGKGIETALKYGSASASIVVSKH 306 Query: 269 GARSAVRPLDEIKKIAQE 286 + A+ ++EI+ + ++ Sbjct: 307 SSSDAMPSVEEIEALIEK 324 >sp|Q57849|Y406_METJA HYPOTHETICAL SUGAR KINASE MJ0406 >gi|2129241|pir||F64350 ribokinase (EC 2.7.1.15) - Methanococcus jannaschii >gi|1592288|gb|AAB98396.1| (U67493) ribokinase (rbsK) [Methanococcus jannaschii] Length = 302 Score = 91.7 bits (224), Expect = 9e-18 Identities = 70/290 (24%), Positives = 130/290 (44%), Gaps = 18/290 (6%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 + C+G+ D +F +EKFP + + GG+A NTA + KLG+ + VG Sbjct: 8 ITCVGHTALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLSCVGY 67 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKY---PGANRWKEVNTE 121 D + + + + ++ S + + + +D + + A +KE+N Sbjct: 68 DFKNSGYERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAAKHYKELNPP 127 Query: 122 YLKRARHLHLSSNPIELIREAVEKAKELGLTVSFDPGE------MEVPRDVEKELDILMM 175 +H+++ E + +KA L VSFDPG+ E+ ++ + + L M Sbjct: 128 NF-NTEIVHIATGDPEFNLKCAKKAYGNNL-VSFDPGQDLPQYSKEMLLEIIEHTNFLFM 185 Query: 176 NEDEFKAKYGSL-----DRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTT 230 N+ EF+ L D ++ V A I G +D+K E+ ++ + K ID T Sbjct: 186 NKHEFERASNLLNFEIDDYLERVDALIVTKGSKGSVIYTKDKKIEIPCIK--AGKVIDPT 243 Query: 231 GGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEI 280 G GD++ AGFL ++ G+D+ +G A V+ G ++ + D++ Sbjct: 244 GAGDSYRAGFLSAYVKGYDLEKCGLIGAATASFVVEAKGCQTNLPTWDKV 293 >pir||E72311 ribokinase - Thermotoga maritima (strain MSB8) >gi|4981498|gb|AAD36039.1|AE001759_3 (AE001759) ribokinase [Thermotoga maritima] Length = 299 Score = 90.5 bits (221), Expect = 2e-17 Identities = 86/302 (28%), Positives = 138/302 (45%), Gaps = 32/302 (10%) Query: 8 MGNLNYDIVFLMEKF--PGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLK-VGFIGAVGN 64 +G+ N DIV ++ F PG +K VF G G N A +AK+G K F+ +GN Sbjct: 8 VGSSNIDIVLKVDHFTKPGETQKAIEMNVFPG--GKGANQAVTVAKIGEKGCRFVTCIGN 65 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMV-KGEDKRIVKYPGANRWKEVNTEYL 123 DD+ L +E + ++G+ +G V+ TG A V K RI+ +PGAN E+ E + Sbjct: 66 DDYSDLLIENYEKLGI--TGYIRVSLPTGRAFIEVDKTGQNRIIIFPGANA--ELKKELI 121 Query: 124 KRARHLHLSSNPIELIREAV------EKAKELGLTVSFDPGEME-VPRDVEKELDILMMN 176 LS + I L++ + E AK V FDP + + ++ + LD L N Sbjct: 122 DWNT---LSESDILLLQNEIPFETTLECAKRFNGIVIFDPAPAQGINEEIFQYLDYLTPN 178 Query: 177 EDEFKAK----YGSL-------DRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAK 225 E E +A +G ++ ++ + I L G L+ + K E K Sbjct: 179 EKEIEALSKDFFGEFLTVEKAAEKFLELGVKNVIVKLGDKGVLLVN-KNEKKHFPTFKVK 237 Query: 226 AIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQ 285 A+DTT GD FN F G + + G A ++V +GA+S++ +E++ + Sbjct: 238 AVDTTAAGDVFNGAFAVALSEGKNPEEAVIFGTAAAAISVTRLGAQSSIPAREEVEAFLK 297 Query: 286 EL 287 L Sbjct: 298 NL 299 >emb|CAA04719.1| (AJ001389) RBSK [Rhizobium etli] Length = 300 Score = 88.2 bits (215), Expect = 1e-16 Identities = 78/296 (26%), Positives = 127/296 (42%), Gaps = 24/296 (8%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 + G++N D++ ++ P E V T GG N A + G V GAVG Sbjct: 2 ITVFGSINMDLIATTDRLPKPGETVAGNSFATAAGGKGANQALAARRAGRYVHMAGAVGK 61 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGE-DKRIVKYPGANRW-----KEV 118 D F L + G D S +K V+ TG A+ +V G+ + I PGAN E Sbjct: 62 DGFAADALALLDDAGTDLSLVKHVDGPTGTALILVGGDGENMIAVVPGANGLVTAADAET 121 Query: 119 NTEYLKRARHLHLSSN-PIELIREAVEKAKELGLT--VSFDPGEMEVPRDVEKELDILMM 175 + L L P++ + A+ +A+ G+T ++ P + PR + + DI++ Sbjct: 122 AVGKMSEGDILMLQLEVPVDAVERALSEARVRGVTSILNLAPLTPDAPR-LGRLADIVIA 180 Query: 176 NEDEF-----------KAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSA 224 NE EF +A+ +L R+ + I TL GG ++ G + +GL Sbjct: 181 NETEFERLAGQDGMDAEAREAALHRLHQETGQTLIVTL-GGDGVIAIRNGVISRAQGLKI 239 Query: 225 KAIDTTGGGDAFNAGFLYGFLSGWDVVNSA-KLGMLLAYLTVQEVGARSAVRPLDE 279 + +DT G GD F F G + SA + + L + GA+ ++ PL + Sbjct: 240 EPVDTVGAGDTFCGYFTASLDEGLRIFASALRRAAVAGSLACLKAGAQPSI-PLSQ 294 >gb|AAD50017.1|AC007651_12 (AC007651) Similar to ribokinase [Arabidopsis thaliana] Length = 378 Score = 86.2 bits (210), Expect = 4e-16 Identities = 85/315 (26%), Positives = 140/315 (43%), Gaps = 34/315 (10%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 ++ +G+ N DI +E+ P E ++AK T GG N A AKL F+G +G Sbjct: 70 LVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGRLGE 129 Query: 65 DDFGRLHLEFFREIGVDTSGI------KVVNDATGIAVTMVKGEDKR-IVKYPGAN--RW 115 D G+L E +G D G+ V N+ TG AV M++ + + I+ GAN W Sbjct: 130 DAHGKLIAE---ALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAW 186 Query: 116 KEV----NTEYLKRARHLHLSSNPIELIREAVEKA-KELGLTVSFDPGEME--VPRDVEK 168 E+ + E ++ A + L + I V KA K+ G+ V D G M+ +P ++ Sbjct: 187 PEIMSDDDLEIVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELLD 246 Query: 169 ELDILMMNEDEFKAKYG----SLDRIKDVKAR--------IAIATLNGGGALVRDEKGEV 216 +DIL NE E G + ++I A+ + + + G AL + + Sbjct: 247 SIDILSPNETELSRLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKGSALFIQGEKPI 306 Query: 217 HEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRP 276 + +A+ +DTTG GD F A F + G + A L VQ + A+ Sbjct: 307 QQSIIPAAQVVDTTGAGDTFTAAFAVAMVEGKSHEECLRFAAAAASLCVQ---VKGAIPS 363 Query: 277 LDEIKKIAQELKLNL 291 + + K + + LK ++ Sbjct: 364 MPDRKSVLKLLKFSI 378 >pir||T07588 fructokinase (EC 2.7.1.4) 1 - tomato >gi|2102691|gb|AAB57733.1| (U64817) fructokinase [Lycopersicon esculentum] Length = 347 Score = 85.4 bits (208), Expect = 7e-16 Identities = 78/275 (28%), Positives = 124/275 (44%), Gaps = 48/275 (17%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 V+C G + D + G+ A GG+ N A ++KLG FIG VG+ Sbjct: 28 VVCFGEMLIDFI---PTVAGV-SLAEAPAFEKAPGGAPANVAVCISKLGGSSAFIGKVGD 83 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDA-TGIAVTMVKGEDKR---IVKYPGAN---RWKE 117 D+FGR+ + ++ VD SG++ +DA T +A + E +R + P A+ R E Sbjct: 84 DEFGRMLADILKQNNVDNSGMRFDHDARTALAFITLTAEGEREFVFFRNPSADMLLRESE 143 Query: 118 VNTEYLKRARHLHLSSNPIELIRE--------AVEKAKELGLTVSFDPGEMEVP------ 163 ++ + +K+A H S I LI E A++ AK G +S+DP + +P Sbjct: 144 LDVDLIKKATIFHYGS--ISLIDEPCRSTHLAAMDIAKRSGSILSYDP-NLRLPLWPSED 200 Query: 164 ------RDVEKELDILMMNEDEFKAKYGS---------LDRIKDVKARIAIATLNGGGA- 207 V DI+ ++EDE G+ L R+ ++ + T G Sbjct: 201 AARSGIMSVWNLADIIKISEDEISFLTGADDPNDDEVVLKRLFHPNLKLLLVTEGSAGCR 260 Query: 208 -LVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFL 241 ++ KG V+ ++ KA+DTTG GDAF G L Sbjct: 261 YYTKEFKGRVNSIK---VKAVDTTGAGDAFTGGVL 292 >dbj|BAB11252.1| (AB010074) fructokinase 1 [Arabidopsis thaliana] Length = 343 Score = 85.4 bits (208), Expect = 7e-16 Identities = 88/324 (27%), Positives = 144/324 (44%), Gaps = 55/324 (16%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 V+C G + D V + G A GG+ N A +++LG FIG VG+ Sbjct: 24 VVCFGEMLIDFVPTV----GGVSLAEAPAFKKAPGGAPANVAVGVSRLGGSSAFIGKVGD 79 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDA-TGIAVTMVKGEDKR---IVKYPGANRW---KE 117 D+FGR+ + R VD SG++ ++A T +A ++G+ +R ++P A+ E Sbjct: 80 DEFGRMLADILRLNNVDNSGMRFDHNARTALAFVTLRGDGEREFLFFRHPSADMLLLESE 139 Query: 118 VNTEYLKRARHLHLSSNPIELIRE--------AVEKAKELGLTVSFDPGEMEVP-----R 164 ++ +++A+ H S I LI E A++ AK G +S+DP + +P Sbjct: 140 LDKNLIQKAKIFHYGS--ISLIEEPCRSTQLVAMKIAKAAGSLLSYDP-NLRLPLWPSEE 196 Query: 165 DVEKEL-------DILMMNEDEFKAKYGSLDRIKD-----------VKARIAIATLNGGG 206 KE+ D++ ++EDE G D D +K + NG Sbjct: 197 AARKEIMSIWNLADVIKISEDEITFLTGGDDPYDDDVVLQKLFHPNLKLLVVSEGPNGCR 256 Query: 207 ALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKL---GMLLA-- 261 ++ KG V G+ K +DTTG GDAF +G L S ++ K +L A Sbjct: 257 YYTQEFKG---RVGGVKVKPVDTTGAGDAFVSGLLNSLASDLTLLKDEKKLREALLFANA 313 Query: 262 --YLTVQEVGARSAVRPLDEIKKI 283 +TV E GA A+ +D ++ + Sbjct: 314 CGAITVTERGAIPAMPSMDAVQDL 337 >dbj|BAB07443.1| (AP001519) 2-keto-3-deoxygluconate kinase [Bacillus halodurans] Length = 317 Score = 85.0 bits (207), Expect = 9e-16 Identities = 79/282 (28%), Positives = 129/282 (45%), Gaps = 34/282 (12%) Query: 37 GLGGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVNDA-TGIA 95 G+GG+ N A +AKLG VG++ VGND+ G+ + R GVDTS + + + A TG+ Sbjct: 30 GVGGAESNVAIGVAKLGHSVGWVSKVGNDELGKYVISAIRGEGVDTSQVVLDDGAPTGLY 89 Query: 96 VTMVKGEDKRIVKY----PGANRW--KEVNTEYLKRARHLH-------LSSNPIELIREA 142 + +D V Y A+R +++N Y+K+A+ +H LS + EL Sbjct: 90 LKEKLRDDFNRVYYYRAGSAASRLGVEDINWAYMKQAKIIHITGITPLLSDSCYELCHAV 149 Query: 143 VEKAKELGLTVSFDPG-----EMEVPRDVEKEL------DILMMNEDEFKAKYGSLDRIK 191 ++ AKE G+ SFDP VP E+ L D++M DE + + D + Sbjct: 150 LDFAKENGIFASFDPNLRMKLLANVPDGKERLLALASKADLVMPGRDEAAFLFDT-DELA 208 Query: 192 DVKARI------AIATLNGG-GALVRDEKGEVHEVRGLSA-KAIDTTGGGDAFNAGFLYG 243 + +R+ ++ +G GA +E E V K +D G GD F AG L Sbjct: 209 QMFSRLLTGRTTSVVIKDGAKGAHFMEEGKEPQFVPSCPVDKVVDPVGAGDGFAAGVLAS 268 Query: 244 FLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQ 285 L G + + +G + L V G + ++++ +Q Sbjct: 269 LLEGKSMEEAVSVGTQIGALVVMAKGDMEGLPEREQLEAFSQ 310 >gb|AAF35840.1|AF205034_3 (AF205034) ScrK [Clostridium acetobutylicum] Length = 316 Score = 82.3 bits (200), Expect = 6e-15 Identities = 76/322 (23%), Positives = 141/322 (43%), Gaps = 54/322 (16%) Query: 4 DVICMGNLNYDIVF-----LMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGF 58 +V+C+G L D + + K +K GG+ N ++KLG F Sbjct: 3 NVLCIGELLIDFICSDIDTTLSKGENFKKKA---------GGAPANVTAAISKLGGSASF 53 Query: 59 IGAVGNDDFGRLHLEFFREIGVDTSGIKVVND-ATGIAVTMVKGEDKRIVKY----PGAN 113 +G VGND FG E E+ VDTS + + N+ +T +A ++ +R + G Sbjct: 54 LGKVGNDPFGHFLKETLDEVKVDTSMLIMDNNSSTTLAFVSLQANGERDFVFNRGADGLL 113 Query: 114 RWKEVNTEYLKRARHLH-------LSSNPIELIREAVEKAKELGLTVSFDPGEME----- 161 R+ E+N + + + +H L + + +E+AK+ G+ +SFDP + Sbjct: 114 RYDEINLDKVYSNKIIHFGSATALLGGEMTDTYLKIMEEAKKRGIIISFDPNYRDNLWEN 173 Query: 162 -------VPRDVEKELDILMMNEDEFKAKYGSLDRIKDVKA-----RIAIATLNGGGALV 209 + R + D + ++++E K G + VK ++ TL G ++ Sbjct: 174 RTEEFIAISRKCIELADFVKLSDEELKIISGEKNIKNGVKLLASNNKVIAVTLGKEGTMI 233 Query: 210 RDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGF---LSGWDVVN-------SAKLGML 259 + + EV + + K+ID+TG GDAF FLY L D+++ + + Sbjct: 234 SNGE-EVEIIESIKIKSIDSTGAGDAFVGAFLYKLSEALEARDILSDFNKIKENVRFANK 292 Query: 260 LAYLTVQEVGARSAVRPLDEIK 281 + + ++GA S++ L E++ Sbjct: 293 VGAIVCTKLGAISSLPSLSEVE 314 >sp|P05054|RBSK_ECOLI RIBOKINASE >gi|66667|pir||KIECRB ribokinase (EC 2.7.1.15) [validated] - Escherichia coli >gi|5822394|pdb|1RK2|B Chain B, E. Coli Ribokinase Complexed With Ribose And Adp, Solved In Space Group P212121 >gi|2981974|pdb|1RKD| E. Coli Ribokinase Complexed With Ribose And Adp >gi|5822395|pdb|1RK2|C Chain C, E. Coli Ribokinase Complexed With Ribose And Adp, Solved In Space Group P212121 >gi|5822393|pdb|1RK2|A Chain A, E. Coli Ribokinase Complexed With Ribose And Adp, Solved In Space Group P212121 >gi|5822396|pdb|1RK2|D Chain D, E. Coli Ribokinase Complexed With Ribose And Adp, Solved In Space Group P212121 >gi|6137732|pdb|1RKA|A Chain A, The Apo Form Of E. Coli Ribokinase >gi|6137733|pdb|1RKS|A Chain A, E. Coli Ribokinase In Complex With D-Ribose >gi|147516|gb|AAA51476.1| (M13169) ribokinase [Escherichia coli] >gi|290602|gb|AAA62105.1| (L10328) ribokinase [Escherichia coli] >gi|1790193|gb|AAC76775.1| (AE000452) ribokinase [Escherichia coli K12] Length = 309 Score = 81.9 bits (199), Expect = 8e-15 Identities = 72/298 (24%), Positives = 123/298 (41%), Gaps = 25/298 (8%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 ++ +G++N D + ++ FP E V GG N A + G + FI G+ Sbjct: 7 LVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFIACTGD 66 Query: 65 DDFGRLHLEFFREIGVDTSGIKVV-NDATGIAVTMVKGEDKRIVK-YPGAN-----RWKE 117 D G + +D + + V+ ++TG+A+ V GE + ++ + GAN E Sbjct: 67 DSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNGEGENVIGIHAGANAALSPALVE 126 Query: 118 VNTEYLKRARHLHLS-SNPIELIREAVEKAKELGLTVSFDPG-EMEVPRDVEKELDILMM 175 E + A L + +P+E + A + A + V+ +P E+P ++ +DI+ Sbjct: 127 AQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVALNPAPARELPDELLALVDIITP 186 Query: 176 NE-------------DEFKAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGL 222 NE DE AK + K + R + TL G GE V G Sbjct: 187 NETEAEKLTGIRVENDEDAAKAAQVLHEKGI--RTVLITLGSRGVWA-SVNGEGQRVPGF 243 Query: 223 SAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEI 280 +A+DT GD FN + L + + + A + V GA+ +V +EI Sbjct: 244 RVQAVDTIAAGDTFNGALITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVPWREEI 301 >sp|O59128|YE59_PYRHO HYPOTHETICAL SUGAR KINASE PH1459 >gi|7434227|pir||F71020 probable fructokinase - Pyrococcus horikoshii >gi|3257883|dbj|BAA30566.1| (AP000006) 310aa long hypothetical fructokinase [Pyrococcus horikoshii] Length = 310 Score = 81.5 bits (198), Expect = 1e-14 Identities = 80/280 (28%), Positives = 132/280 (46%), Gaps = 32/280 (11%) Query: 39 GGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGI-KVVNDATGIAVT 97 GG+ N A +++LG+K I VGND FG +E + VDT GI K TGI Sbjct: 37 GGAPANVAVGVSRLGVKSSLISKVGNDPFGEYLIEELSKENVDTRGIVKDEKKHTGIVFV 96 Query: 98 MVKGEDKRIVKYPGANRW----KEVNTEYLKRARHLH-----LSSNPI-ELIREAVEKAK 147 +KG + Y + ++N + ++ A+ ++ L+ NP E + + ++K K Sbjct: 97 QLKGASPSFLLYDDVAYFNMTLNDINWDIVEEAKIVNFGSVILARNPSRETVMKVIKKIK 156 Query: 148 ELGLTVSFDPG-EMEVPRDVEKEL-----------DILMMNEDEFKAKYGSLDRIKDVKA 195 L ++FD +++ R E+E+ DI+ +E+E Y ++ + Sbjct: 157 GSSL-IAFDVNLRLDLWRGQEEEMIKVLEESIKLADIVKASEEE--VLYLENQGVEVKGS 213 Query: 196 RIAIATLNGGGA-LVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGF--LSGWDVVN 252 + TL G L+++E V +V + +DTTG GDAF A L G L G D++ Sbjct: 214 MLTAITLGPKGCRLIKNE--TVVDVPSYNVNPLDTTGAGDAFMAALLVGILKLKGLDLLK 271 Query: 253 SAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQELKLNLP 292 K L+A L+ Q+ GA S R DE+ K + ++ P Sbjct: 272 LGKFANLVAALSTQKRGAWSTPRK-DELLKYKEAREVLAP 310 >dbj|BAB16906.1| (AP002863) contains ESTs AU029689(EE1266),C91697(EE1266)~unknown protein [Oryza sativa] Length = 377 Score = 81.1 bits (197), Expect = 1e-14 Identities = 80/295 (27%), Positives = 126/295 (42%), Gaps = 30/295 (10%) Query: 6 ICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWL-AKLGLKVGFIGAVGN 64 +C+ LN+ + + + + +++ + T GGS NT L A G+ G IGA G+ Sbjct: 67 VCIEELNHILAEVNAQILPCRDDLSS--IRTIAGGSVANTIRGLSAGFGISTGIIGACGD 124 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKYPGANRWK----EVNT 120 D G L + GVD + ++ T A +V R ++ ++ K E Sbjct: 125 DSQGVLFVSNMSFSGVDLTRLRTKKGHT--AQCLVDASGNRTMRPCLSSAVKLQANEFKK 182 Query: 121 EYLKRARHL--HLSSNPIELIREAVEKAKELGLTVSFDPGEMEVPRDVEKEL-------- 170 E K ++ L + +E I EA+ AK+ GL+VS D E+ RD +L Sbjct: 183 EDFKGSKWLVVRYARQNMEQILEAIRIAKQEGLSVSLDLASFEMVRDYRTQLIDLLETGN 242 Query: 171 -DILMMNEDEFKAKYGSLDRIKDVKA--------RIAIATLNGGGALVRDEKGEVHEVRG 221 D+ NEDE + G +A + A+ TL G + + K V Sbjct: 243 IDLCFANEDEARELLGGELTFDPEEALAFLAKYCKWAVVTLASKGCIAKHGKQVVQVAAT 302 Query: 222 LSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRP 276 + A+D TG GD F +GFLYG + G + K+G V+ +G VRP Sbjct: 303 GESNAVDATGAGDLFASGFLYGLVKGLALEECCKVGACSGGSVVRALGGE--VRP 355 >pir||T01971 fructokinase (EC 2.7.1.4) - Arabidopsis thaliana >gi|3695403|gb|AAC62803.1| (AF096373) contains similarity to the pfkB family of carbohydrate kinases (Pfam: PF00294, E=1.6e-75) [Arabidopsis thaliana] >gi|4538955|emb|CAB39779.1| (AL049488) fructokinase-like protein [Arabidopsis thaliana] >gi|7267722|emb|CAB78149.1| (AL161516) fructokinase-like protein [Arabidopsis thaliana] Length = 324 Score = 80.4 bits (195), Expect = 2e-14 Identities = 71/242 (29%), Positives = 114/242 (46%), Gaps = 36/242 (14%) Query: 33 GVFTGLGGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKV-VNDA 91 G GG+ N A + KLG K FIG G+D+FG + + ++ GV++ G+ N Sbjct: 31 GFLKAPGGAPANVACAITKLGGKSAFIGKFGDDEFGHMLVNILKKNGVNSEGVCFDTNAR 90 Query: 92 TGIA-VTMVKGEDKRIVKY--PGAN---RWKEVNTEYLKRARHLHLSSNPIELIRE---- 141 T +A VT+ K ++ + Y P A+ + E+N + +K+A+ H S I LI E Sbjct: 91 TALAFVTLKKDGEREFMFYRNPSADMLLKESELNKDLIKKAKIFHYGS--ISLISEPCRT 148 Query: 142 ----AVEKAKELGLTVSFDP-----------GEMEVPRDVEKELDILMMNEDEFKAKYGS 186 A++ AK+ G+ +S+DP +E + + E DI+ +++DE Sbjct: 149 AHMAAMKTAKDAGVLLSYDPNVRLPLWPSTEAAIEGIKSIWNEADIIKVSDDEVTFLTRG 208 Query: 187 LDRIKDV-------KARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAG 239 DV K ++ I T G +K + V G + KA+DTTG GD+F Sbjct: 209 DAEKDDVVLSLMHDKLKLLIVTDGEKGCRYYTKKFK-GRVPGYAVKAVDTTGAGDSFVGA 267 Query: 240 FL 241 FL Sbjct: 268 FL 269 >gb|AAK42589.1| Ribokinase (rbsK-2) [Sulfolobus solfataricus] Length = 283 Score = 80.0 bits (194), Expect = 3e-14 Identities = 74/293 (25%), Positives = 137/293 (46%), Gaps = 23/293 (7%) Query: 6 ICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGND 65 + +G N DI+ ++ P I + GG+A N A + KLG + VG Sbjct: 4 LAVGRFNIDIIVKLDSIPPIDSSHMTDVLEIMPGGAATNYAVAVTKLGHSAKLLAKVGKS 63 Query: 66 DFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDK-RIVKYPGANRWKEVNTEYLK 124 + R +E E+GV ++ +N+ + ++ + +V+ GA+ + E +K Sbjct: 64 EVVRSLMEKVVELGVGLEYVEELNEKPSATLIFLRNDGTLSMVRRLGASIL--LTREDVK 121 Query: 125 RARHL----HLSS-NPIELIREAVEKAKELGLTVSFDPGEMEVPRDVEK-ELDILMMNED 178 R L H +S +P ++R+ K VS+DPG +++E ++DIL +NE Sbjct: 122 RRFGLFDVIHFASVSPNVVVRDPYAKL------VSYDPGPQA--KNIESVDVDILYVNEK 173 Query: 179 EFKAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNA 238 E++ + K+++AR + + GA + E E K +DTTG GD F+A Sbjct: 174 EYE-----MIEDKNIRARFIVIKMGKKGAKIITETEECSVEPIQVEKIVDTTGAGDTFDA 228 Query: 239 GFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQELKLNL 291 F + D+V S ++ + + L V +G S+ L+E+++ ++ K N+ Sbjct: 229 AFNVTYSEDKDIVKSLQVASVASGLKVSRIGGISS-PTLEEVREYLRKKKPNV 280 >gb|AAF79436.1|AC025808_18 (AC025808) F18O14.35 [Arabidopsis thaliana] >gi|9795587|gb|AAF98405.1|AC024609_6 (AC024609) Unknown protein [Arabidopsis thaliana] Length = 355 Score = 78.0 bits (189), Expect = 1e-13 Identities = 68/256 (26%), Positives = 108/256 (41%), Gaps = 26/256 (10%) Query: 39 GGSAGNTATWLAK-LGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVT 97 GGS NT L+ G+ G IGA G+D+ G+L + GV S ++ +T V Sbjct: 74 GGSVTNTVRGLSVGFGVATGIIGAYGDDEQGQLFVSNMGFSGVSISRLRKKKGSTAQCVC 133 Query: 98 MVKGEDKRIVKYPGANRWKEVNTEYLKRARH-------LHLSSNPIELIREAVEKAKELG 150 +V R ++ P + ++ + L + L + +++I+ A+ AK+ G Sbjct: 134 LVDDSGNRTMR-PCLSSAVKIQADELSKEDFTGSKWLVLRYAVLNLQVIQAAIRFAKQEG 192 Query: 151 LTVSFDPGEMEVPRDVEKEL---------DILMMNEDEFKAKYGSLDRIKDVKA------ 195 L+VS D E+ R+ + EL D+ NEDE A Sbjct: 193 LSVSLDLASFEMVRNSKSELRQLLESGNIDLCFANEDEAAELLRGEQEAGPEAALEFLGR 252 Query: 196 --RIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNS 253 R A+ TL G + + +K VH A D TG GD F +GFLYG + G + Sbjct: 253 HCRWAVVTLGSKGCIAKHDKEVVHISAIGETVATDATGAGDLFASGFLYGLIKGLSLEEC 312 Query: 254 AKLGMLLAYLTVQEVG 269 K+G ++ +G Sbjct: 313 CKVGSCSGGSVIRALG 328 >dbj|BAB05576.1| (AP001513) fructokinase [Bacillus halodurans] Length = 319 Score = 77.3 bits (187), Expect = 2e-13 Identities = 86/324 (26%), Positives = 136/324 (41%), Gaps = 53/324 (16%) Query: 1 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG 60 M VIC+G D + M+ I++K GG+ N A LAKLG K F+G Sbjct: 1 MNRGVICLGEALIDFI-PMDSTNEIYQK--------SPGGAPANVAVGLAKLGAKSTFVG 51 Query: 61 AVGNDDFGRLHLEFFREIGVDTSGIKVVNDA-TGIAVTMVKGEDKRIVKY---PGANRW- 115 VG+D GR E + V+T + + TG + +R + P A+R+ Sbjct: 52 KVGDDLLGRFLKETLTKANVNTEHMLFSKEVRTGATFVTLAANGERSFDFYINPSADRFL 111 Query: 116 --KEVNTEYLKRARHLHLSSNPIELI--------REAVEKAKELGLTVSFDPG-EMEVPR 164 E+ + LH S I LI R AV AK+ GL +S+DP + + Sbjct: 112 EKGEIAPTLFEEHGVLHFGS--ISLISEPARTATRHAVSLAKKNGLMISYDPNLRLNLWE 169 Query: 165 DVEK----------ELDILMMNEDEFKAKYG------SLDRIKDVKARIAIATLNGGGAL 208 D E+ E D+L ++E+E G LD++ + TL G++ Sbjct: 170 DEEQARLLITSMLGEADVLKISEEELAFITGEQTIEAGLDQLVAYNIPLVFVTLGEKGSI 229 Query: 209 VRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGF---------LSGWDVVNSAKLGML 259 V G ++ ++ + +DTTG GDAF + L+ LS +V A+ + Sbjct: 230 V-SYNGIQRKIPAMAVQTVDTTGAGDAFVSAILFKLQEERKQVAELSIKEVEQMARFASV 288 Query: 260 LAYLTVQEVGARSAVRPLDEIKKI 283 L GA +A+ L+++ I Sbjct: 289 SGGLAAATKGAMTALPTLEKVNDI 312 >pir||T46874 ribokinase homolog [imported] - Sulfolobus solfataricus >gi|1706952|gb|AAB38089.1| (U52110) ribokinase [Sulfolobus solfataricus] Length = 287 Score = 76.9 bits (186), Expect = 3e-13 Identities = 66/272 (24%), Positives = 125/272 (45%), Gaps = 22/272 (8%) Query: 6 ICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGND 65 + +G +N DI+ + K P I E + GG+A N A + K G + + +G D Sbjct: 6 LSVGRINIDIIAKINKIPDIDEFETTDTLEILPGGAAVNYAVAINKFGHSIKILSKIGKD 65 Query: 66 DFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDK-RIVKYPGANRWKEVNTEYLK 124 LE E+GV ++ N +A+ ++ +V+ G++ ++ E +K Sbjct: 66 SLVSYVLERIAEMGVGLDYVEETNLPQSMALIFLRDNGSISMVRKLGSSIL--LDKEDIK 123 Query: 125 RARHL----HLSS-NPIELIREAVEKAKELGLTVSFDPG--EMEVPRDVEKELDILMMNE 177 + L H +S +P ++R+ K +++DPG ++P + DI+ +NE Sbjct: 124 KVFGLFDVIHFASISPDIVVRDPYAKL------ITYDPGPNSSKIPENFGNA-DIIYLNE 176 Query: 178 DEFKAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFN 237 E + +I+ +KAR+ + + GA V E E + +DTTG GD F+ Sbjct: 177 RE-----STKVKIESLKARLIVIKMGSKGAKVISENEECYCEPYKVQTVLDTTGAGDVFD 231 Query: 238 AGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVG 269 A F Y ++ G+ + ++ + + + L V +G Sbjct: 232 AAFNYAYVQGYSIEDTLRFAVTASALKVMRIG 263 >gb|AAC98130.1| (AF098273) 2-keto-3-deoxy-gluconate kinase [Bacillus stearothermophilus] Length = 314 Score = 74.1 bits (179), Expect = 2e-12 Identities = 64/233 (27%), Positives = 103/233 (43%), Gaps = 31/233 (13%) Query: 38 LGGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIK-VVNDATGIAV 96 +GG N A LA+LG +VG+I VG+D+FG+ L F + GVD S +K + N + Sbjct: 31 IGGRESNVAVGLARLGHRVGWISKVGSDEFGKAILSFLKGEGVDVSRVKWMGNTDRHLLK 90 Query: 97 TMVKGEDKRIVKY---PGANRW--KEVNTEYLKRARHLH-------LSSNPIELIREAVE 144 + D R+ Y A+R +++ +Y+ A++LH LS N + + A+ Sbjct: 91 EQRRLNDTRVYYYRKGSAASRLTPADLDEKYIAEAKYLHITGITPALSENCRDTVFAAMA 150 Query: 145 KAKELGLTVSFDPG-----------EMEVPRDVEKELDILMMNEDEFKAKYGSL------ 187 A+ G+ + FDP EV + E D+++ E E +G Sbjct: 151 MARRHGVKIVFDPNLRLKLWNEADRAKEVMLRMAAESDVVLPGEAEASFLFGKHSVEEWG 210 Query: 188 DRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGF 240 R+ D+ A + + L GA + V+G K D G GD F G+ Sbjct: 211 SRLLDMGASLVVIKLGANGAHYFTNAHHEY-VQGFLLKGYDPVGAGDGFVEGY 262 >pir||E75385 carbohydrate kinase, PfkB family - Deinococcus radiodurans (strain R1) >gi|6459287|gb|AAF11090.1|AE001996_5 (AE001996) carbohydrate kinase, PfkB family [Deinococcus radiodurans] Length = 311 Score = 74.1 bits (179), Expect = 2e-12 Identities = 78/311 (25%), Positives = 138/311 (44%), Gaps = 28/311 (9%) Query: 1 MRFDVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIG 60 M+F VI G++ D ++ +++ P ++V K GGS G + LA+LG V Sbjct: 1 MKFYVI--GDVTVDHLYHLDRLPAPGKEVTPKRSTMQPGGSGGTISVTLARLGHTVTLAA 58 Query: 61 AVGNDDFGRLHLEFFREIGVDTSGIKVVND--ATGIAVTMVKGEDKRIVKYPGANRWKE- 117 VG+D F L + GV S I+ + + I V G + ++ ANR + Sbjct: 59 RVGDDPFAEFALAEIKASGVSLSAIQKDPEHLTSTITVMQTSGGQRAMISDGAANRQLDP 118 Query: 118 --VNTEYLKRARHLHLSSNPI------ELIREAVEKA----KELGLTVSFDPGEME-VPR 164 + + ++ A L +S+ + E ++A+E A K + + + G +E V Sbjct: 119 AKLKKKDVESADALIISAYSLTEGPQREYAQKAIEIARGAKKPVPVFIDLGTGAVEKVGT 178 Query: 165 DVEKEL---DILMMNEDEFKAKYGS------LDRIKDVKA-RIAIATLNGGGALVRDEKG 214 + E+ D L +N+ E A G+ L R+ + R+A+ G + E Sbjct: 179 GLVAEVRGADYLTLNQHELLALTGTRSLSAGLARLAEAGVERVAVKVGKMGSVVWTPEDT 238 Query: 215 EVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAV 274 E+ + +DTTG GD F A F + LSG + +A++ L VGA+S Sbjct: 239 ELVDAVLPEGTVVDTTGAGDTFTAAFAHAVLSGLPLTQAARVANAAGALAATAVGAQSKP 298 Query: 275 RPLDEIKKIAQ 285 + +++++AQ Sbjct: 299 ILVGDLERVAQ 309 >pir||A75599 ribokinase - Deinococcus radiodurans (strain R1) >gi|6460552|gb|AAF12258.1|AE001862_84 (AE001862) ribokinase [Deinococcus radiodurans] Length = 300 Score = 74.1 bits (179), Expect = 2e-12 Identities = 71/286 (24%), Positives = 115/286 (39%), Gaps = 10/286 (3%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 V+ +G+ N D V + P E V + T GG N A A+ G V F GA+G Sbjct: 12 VLVVGSANLDFVTRLSHLPAPGETVLGESYTTAPGGKGANQAVACARAGGAVAFCGALGT 71 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKYPGAN-RWKEVNTEYL 123 D F L RE GV ++ +++ + + I GAN + L Sbjct: 72 DPFAEPLLASLRESGVQDWTVRASTPTGAAFISVSEAGENCIAVASGANGTLRPEQLPPL 131 Query: 124 KRARHLHLSSN-PIELIREAVEKAKELGLTVSFDPGEME-VPRDVEKELDILMMNEDEFK 181 L L P+E ++ A + A+E G V + +P ++ + +D+L++NE E + Sbjct: 132 TGVGWLVLQLEIPLETVQAAAQAAREAGAQVVLNAAPARTLPPELLRLVDVLIVNEGELR 191 Query: 182 AKYGSLDRIKDVK------ARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDA 235 G+ D V+ R + TL G L + E+ L DTTG GD Sbjct: 192 TLIGATDLRAGVRQAQASGPRTVVVTLGERGCLAL-SGDDWTELPALPVPVRDTTGAGDT 250 Query: 236 FNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIK 281 F + G + + + + L GA+ A+ +EI+ Sbjct: 251 FVGVLVAALSRGEPFAAALRWAVAGSALACTREGAQPAMPGREEIQ 296 >gi|11545855 ribokinase [Homo sapiens] >gi|10799803|emb|CAC12877.1| (AJ404857) ribokinase [Homo sapiens] Length = 322 Score = 74.1 bits (179), Expect = 2e-12 Identities = 79/299 (26%), Positives = 125/299 (41%), Gaps = 36/299 (12%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 V+ +G+ D+V L + P E ++ F G GG N A+LG + VG Sbjct: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVND-ATGIAVTMVKGEDKR-IVKYPGANRWKEVNTEY 122 D FG ++E ++ + T D ATG A +V E + IV GAN +NTE Sbjct: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLL--LNTED 135 Query: 123 LKRARHL---------HLSSNPIELIREAVEKAKELGLTVSFDPGEMEVPRDVE--KELD 171 L+ A ++ L P + EA+ A+ G+ F+P D + D Sbjct: 136 LRAAANVISRAKVMVCQLEITPATSL-EALTMARRSGVKTLFNPAPAIADLDPQFYTLSD 194 Query: 172 ILMMNEDEFKAKYG-SLDRIKDV----------KARIAIATLNGGGALVRDE-KGEVHEV 219 + NE E + G ++ D ++ I TL G +V + + E + Sbjct: 195 VFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHI 254 Query: 220 RGLSAKAIDTTGGGDAFNAGF-----LYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSA 273 KA+DTTG GD+F Y LS D++N + +A ++VQ G +S+ Sbjct: 255 PTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSN---FIAAVSVQAAGTQSS 310 >gb|AAG12908.1|AC020665_17 (AC020665) fructokinase, putative; 80047-82040 [Arabidopsis thaliana] >gi|11054541|gb|AAG27840.1|AC074025_10 (AC074025) fructokinase, putative [Arabidopsis thaliana] Length = 384 Score = 73.4 bits (177), Expect = 3e-12 Identities = 74/273 (27%), Positives = 113/273 (41%), Gaps = 45/273 (16%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 V+C G + D V +A GG+ N A +A+LG FIG VG Sbjct: 66 VVCFGEMLIDFVPTTSGL----SLADAPAFKKAPGGAPANVAVGIARLGGSSAFIGKVGE 121 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDA-TGIAVTMVKGEDKR---IVKYPGAN---RWKE 117 D+FG + ++ V+ G++ A T +A + E +R + P A+ E Sbjct: 122 DEFGYMLANILKDNNVNNDGMRFDPGARTALAFVTLTNEGEREFMFYRNPSADMLLEESE 181 Query: 118 VNTEYLKRARHLHLSSNPIELIRE--------AVEKAKELGLTVSFDP-----------G 158 ++ + +K+A+ H S I LI E A + AKE G+ +S+DP Sbjct: 182 LDFDLIKKAKIFHYGS--ISLITEPCKSAHISAAKAAKEAGVILSYDPNLRLPLWPSADN 239 Query: 159 EMEVPRDVEKELDILMMNEDEFKAKYGSLDRIKD--------VKARIAIATLNGGGA--L 208 E + + DI+ ++E+E D D K ++ + T G Sbjct: 240 AREEILSIWETADIIKISEEEIVFLTKGEDPYDDNVVRKLFHPKLKLLLVTEGPEGCRYY 299 Query: 209 VRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFL 241 +D G VH GL +DTTG GDAF AG L Sbjct: 300 TKDFSGRVH---GLKVDVVDTTGAGDAFVAGIL 329 >gb|AAF80125.1|AC024174_7 (AC024174) Contains similarity to a fructokinase from Lycopersicon esculentum gi|1915974 and is a member of the pfkB carbohydrate kinase family PF|00294. [Arabidopsis thaliana] Length = 345 Score = 73.0 bits (176), Expect = 4e-12 Identities = 70/264 (26%), Positives = 113/264 (42%), Gaps = 37/264 (14%) Query: 33 GVFTGLGGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVNDA- 91 G GG+ N A +++LG + F+G +G+DDFG + R+ GVD GI A Sbjct: 35 GFLKAPGGAPANVAIAVSRLGGRAAFVGKLGDDDFGHMLAGILRKNGVDDQGINFDEGAR 94 Query: 92 TGIAVTMVKGEDKR---IVKYPGAN---RWKEVNTEYLKRARHLHLSSNPIELIRE---- 141 T +A ++ + +R + P A+ R E+N E ++ A+ H S I LI E Sbjct: 95 TALAFVTLRSDGEREFMFYRNPSADMLLRPDELNLELIRSAKVFHYGS--ISLITEPCRS 152 Query: 142 ----AVEKAKELGLTVSFDPGEME----VPRDVEKELDILMMNEDEFKAKYGSLDRIKDV 193 A+E AKE G +S+DP E P + ++ + D K L+ + + Sbjct: 153 AHMKAMEVAKEAGALLSYDPNLREPLWPSPEEARTQIMSIWDKADIIKVSDVELEFLTEN 212 Query: 194 KA--------------RIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAG 239 K ++ + TL G +K V A+DTTG GD+F Sbjct: 213 KTMDDKTAMSLWHPNLKLLLVTLGEKGCTYFTKKFH-GSVETFHVDAVDTTGAGDSFVGA 271 Query: 240 FLYGFLSGWDVV-NSAKLGMLLAY 262 L + V+ + A+L +L + Sbjct: 272 LLQQIVDDQSVLEDEARLRKVLRF 295 >pir||G75112 fructokinase (EC 2.7.1.4) PAB0482 - Pyrococcus abyssi (strain Orsay) >gi|5458127|emb|CAB49616.1| (AJ248285) FRUCTOKINASE (EC 2.7.1.4) [Pyrococcus abyssi] Length = 305 Score = 72.6 bits (175), Expect = 5e-12 Identities = 72/275 (26%), Positives = 121/275 (43%), Gaps = 33/275 (12%) Query: 39 GGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGI-KVVNDATGIAVT 97 GG+ N A +A+LG + VG+D FG +E R V T GI K TGI Sbjct: 35 GGAPANVAVGIARLGFDSCLVSKVGDDPFGEFLVESLRRENVKTDGIVKDEEKHTGIVFV 94 Query: 98 MVKGEDKRIVKYPGAN----RWKEVNTEYLKRARHLHLSSNPI------ELIREAVEKAK 147 + G + Y G R +++N E + +R +H S + E + + +++ K Sbjct: 95 QLTGVSPSFILYDGVAYFNLRREDINWELINSSRIVHFGSVILARSPSRETVLDVIKRVK 154 Query: 148 ELGLTVSFDPG-EMEV----PRDVEKELDILMMNEDEFKAKYGSLDRIKD----VKARIA 198 + VSFD +++ D+ + ++ + D KA +D ++D V+ ++ Sbjct: 155 TI---VSFDVNLRLDLWKNRGEDMLRTIEEAIKLADIVKASEEEVDYLEDNGIEVEGKLI 211 Query: 199 IATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNS----- 253 A G + K +V G +DTTG GDAF A L G + ++ N Sbjct: 212 TAITMGS----KGAKLNGIQVPGYKVNPVDTTGAGDAFTAALLVGIMKVREITNENLEKI 267 Query: 254 AKLGMLLAYLTVQEVGARSAVRPLDEIK-KIAQEL 287 K L+A L+ + GA S + + +K K A+E+ Sbjct: 268 GKFANLVAALSTLKRGAWSVPKVEELLKYKEAREI 302 >sp|P40713|SCRK_ECOLI FRUCTOKINASE >gi|1073355|pir||S52161 probable fructokinase (EC 2.7.1.4) - Escherichia coli >gi|608707|emb|CAA57218.1| (X81461) D-fructokinase [Escherichia coli] Length = 305 Score = 71.8 bits (173), Expect = 9e-12 Identities = 74/240 (30%), Positives = 105/240 (42%), Gaps = 36/240 (15%) Query: 39 GGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVN-DATGIAVT 97 GG+ N A +A+LG GFIG VG+D FG L GVD + +K T + Sbjct: 28 GGAPANVAVGIARLGGTSGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWHRTSTVLV 87 Query: 98 MVKGEDKRIVKY---PGANRWKEVNTEYLKRARH---LHLSSNPIELIRE--------AV 143 + + +R + P A+ + E T L RH LHL S I L E A+ Sbjct: 88 DLNDQGERSFTFMVRPSADLFLE--TTDLPCWRHGEWLHLCS--IALSAEPSRTSAFTAM 143 Query: 144 EKAKELGLTVSFDPGEME-----------VPRDVEKELDILMMNEDEFKAKYGSLDRIKD 192 + G VSFDP E R + D++ ++E+E++ G +D Sbjct: 144 TAIRHAGGFVSFDPNIREDLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRD 203 Query: 193 VKA---RIAIATL---NGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLS 246 + A IA L G +V +G+VH G+S +D+TG GDAF AG L G S Sbjct: 204 ICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMSVNCVDSTGAGDAFVAGLLTGLSS 263 >gb|AAF80126.1|AC024174_8 (AC024174) Contains similarity to a fructokinase from Solanum tuberosum gi|585973 and is a member of the pfkB carbohydrate kinase family PF|00294. [Arabidopsis thaliana] Length = 329 Score = 71.8 bits (173), Expect = 9e-12 Identities = 70/247 (28%), Positives = 111/247 (44%), Gaps = 42/247 (17%) Query: 31 AKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVND 90 + G GG+ N A +++LG + F+G +G+D+FG + R+ VD GI Sbjct: 34 SSGFLKAPGGAPANVAIAVSRLGGRAAFVGKLGDDEFGHMLAGILRKNDVDDQGINFDKG 93 Query: 91 A-TGIAVTMVKGEDKR---IVKYPGAN---RWKEVNTEYLKRARHLHLSSNPIELIRE-- 141 A T +A ++ + +R + P A+ R E+N E ++ A+ H S I LI E Sbjct: 94 ARTALAFVTLRSDGEREFMFYRNPSADMLLRPDELNLELIRSAKVFHYGS--ISLITEPC 151 Query: 142 ------AVEKAKELGLTVSFDPGEME----VPRDVEKEL-------DILMMNEDEFKAKY 184 A+E AKE G +S+DP E P + K++ DI+ +++ E + Sbjct: 152 RSAHMKAMEVAKEAGALLSYDPNLREPLWPSPEEARKQIMSIWDKADIIKVSDVELEFLT 211 Query: 185 GSLDRIKDVKA--------RIAIATL--NGGGALVRDEKGEVHEVRGLSAKAIDTTGGGD 234 G+ I D A ++ + TL NG +D G V A+DTTG GD Sbjct: 212 GN-KTIDDETAMSLWHPNLKLLLVTLGENGCRYYTKDFHGSVET---FHVDAVDTTGAGD 267 Query: 235 AFNAGFL 241 +F L Sbjct: 268 SFVGALL 274 >sp|P36945|RBSK_BACSU RIBOKINASE >gi|7427979|pir||D69690 ribokinase (EC 2.7.1.15) - Bacillus subtilis >gi|1894761|emb|CAB07465.1| (Z92953) ribokinase [Bacillus subtilis] >gi|2636117|emb|CAB15609.1| (Z99122) ribokinase [Bacillus subtilis] Length = 293 Score = 70.2 bits (169), Expect = 3e-11 Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 13/291 (4%) Query: 4 DVICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVG 63 ++ +G+ + D+V +K P E V T GG N A A+LG +V +G VG Sbjct: 3 NICVIGSCSMDLVVTSDKRPKAGETVLGTSFQTVPGGKGANQAVAAARLGAQVFMVGKVG 62 Query: 64 NDDFGRLHLEFFREIGVDTSGIK-VVNDATGIAVTMVKGEDKRIVKYPGANRWKEVNTEY 122 +D +G L + GV T ++ V + +G A ++ D IV GAN ++ Y Sbjct: 63 DDHYGTAILNNLKANGVRTDYMEPVTHTESGTAHIVLAEGDNSIVVVKGAN--DDITPAY 120 Query: 123 LKRARH--------LHLSSNPIELIREAVEKAKELGLTVSFDPGEME-VPRDVEKELDIL 173 A L P E + E + + + +P + ++ L Sbjct: 121 ALNALEQIEKVDMVLIQQEIPEETVDEVCKYCHSHDIPIILNPAPARPLKQETIDHATYL 180 Query: 174 MMNEDEFKAKYGSLDRIKDVKARIAIATLNGGGALVRDEKGEVHE-VRGLSAKAIDTTGG 232 NE E + L + + A + G VR G + + +DTTG Sbjct: 181 TPNEHEASILFPELTISEALALYPAKLFITEGKQGVRYSAGSKEVLIPSFPVEPVDTTGA 240 Query: 233 GDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKI 283 GD FNA F G D+ + + A L+V GA+ + +E++++ Sbjct: 241 GDTFNAAFAVALAEGKDIEAALRFANRAASLSVCSFGAQGGMPTRNEVEEL 291 >pir||T49289 fructokinase-like protein - Arabidopsis thaliana >gi|6996284|emb|CAB75445.1| (AL138659) fructokinase-like protein [Arabidopsis thaliana] Length = 326 Score = 69.9 bits (168), Expect = 3e-11 Identities = 65/249 (26%), Positives = 115/249 (46%), Gaps = 44/249 (17%) Query: 30 NAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVN 89 +A G GG+ N A +++LG + F+G +G+D+FG + ++ GV GI Sbjct: 32 DAPGFIKAPGGAPANVAIAISRLGGRAAFVGKLGDDEFGHMLAGILKQNGVSAEGINFDT 91 Query: 90 DA-TGIAVTMVKGEDKR---IVKYPGAN---RWKEVNTEYLKRARHLHLSSNPIELIRE- 141 A T +A ++ + +R + P A+ R E+N + ++ A+ H S I LI E Sbjct: 92 GARTALAFVTLRSDGEREFMFYRNPSADMLLRPDELNLDVIRSAKVFHYGS--ISLIVEP 149 Query: 142 -------AVEKAKELGLTVSFDPGEMEVP-----RDVEKEL-------DILMMNEDEFKA 182 A+E AKE G +S+DP + +P + +K++ +++ ++++E Sbjct: 150 CRSAHLKAMEVAKEAGALLSYDP-NLRLPLWPSKEEAQKQILSIWDKAEVIKVSDEELMF 208 Query: 183 KYGSLDRIKDVKA--------RIAIATLNGGGA--LVRDEKGEVHEVRGLSAKAIDTTGG 232 GS D++ D A ++ + TL G + +G V A+DTTG Sbjct: 209 LTGS-DKVDDETALSLWHSNLKLLLVTLGEKGCRYYTKSFRGSVDP---FHVDAVDTTGA 264 Query: 233 GDAFNAGFL 241 GD+F L Sbjct: 265 GDSFVGALL 273 >gi|10383797 ribokinase; Rbk1p [Saccharomyces cerevisiae] Length = 333 Score = 69.9 bits (168), Expect = 3e-11 Identities = 79/333 (23%), Positives = 137/333 (40%), Gaps = 55/333 (16%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLG-----LKVGFI 59 + +G+LNYD+ ++ P E A T GG N A + KL V I Sbjct: 3 ITVIGSLNYDLDTFTDRLPNAGETFRANHFETHAGGKGLNQAAAIGKLKNPSSRYSVRMI 62 Query: 60 GAVGNDDFGRLHLEFFREIGVDTSGIKVVNDA-TGIAVTMVK---GEDKRIVKYPGAN-- 113 G VGND FG+ + + GVD + + TG A +++ G RI+ GAN Sbjct: 63 GNVGNDTFGKQLKDTLSDCGVDITHVGTYEGINTGTATILIEEKAGGQNRILIVEGANSK 122 Query: 114 ------RWKEVNTEYLKRARHL---HLSSNPIELIREAVEKAKELGLTVSFDPGEME-VP 163 + E+ E + ++ H +P+ +I+ A + ++P + +P Sbjct: 123 TIYDPKQLCEIFPEGKEEEEYVVFQHEIPDPLSIIKWI--HANRPNFQIVYNPSPFKAMP 180 Query: 164 RDVEKELDILMMNE------------------------DEFKAKYGSL-----DRIKDVK 194 + + +D+L++NE D+F +Y + +++ + K Sbjct: 181 KKDWELVDLLVVNEIEGLQIVESVFDNELVEEIREKIKDDFLGEYRKICELLYEKLMNRK 240 Query: 195 AR-IAIATLNGGGALV-RDEKGEVHEVRGL-SAKAIDTTGGGDAFNAGFLYGFLSGWDVV 251 R I + TL G L E EV + + + +DTTG GD F G + G + Sbjct: 241 KRGIVVMTLGSRGVLFCSHESPEVQFLPAIQNVSVVDTTGAGDTFLGGLVTQLYQGETLS 300 Query: 252 NSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIA 284 + K L + LT+Q GA ++ +++K A Sbjct: 301 TAIKFSTLASSLTIQRKGAAESMPLYKDVQKDA 333 >sp|P25332|RBSK_YEAST PROBABLE RIBOKINASE >gi|279503|pir||KIBYRB ribokinase (EC 2.7.1.15) - yeast (Saccharomyces cerevisiae) >gi|4492|emb|CAA40228.1| (X56909) ribokinase [Saccharomyces cerevisiae] >gi|1907178|emb|CAA42303.1| (X59720) YCR036w, len:333 [Saccharomyces cerevisiae] Length = 333 Score = 69.1 bits (166), Expect = 6e-11 Identities = 79/333 (23%), Positives = 137/333 (40%), Gaps = 55/333 (16%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLG-----LKVGFI 59 + +G+LNYD+ ++ P E A T GG N A + KL V I Sbjct: 3 ITVIGSLNYDLDTFTDRLPNAGETFRANHFETHAGGKGLNQAAAIGKLKNPSSRYSVRMI 62 Query: 60 GAVGNDDFGRLHLEFFREIGVDTSGIKVVNDA-TGIAVTMVK---GEDKRIVKYPGAN-- 113 G VGND FG+ + + GVD + + TG A +++ G RI+ GAN Sbjct: 63 GNVGNDTFGKQLKDTLSDCGVDITHVGTYEGINTGTATILIEEKAGGQNRILIVEGANSK 122 Query: 114 ------RWKEVNTEYLKRARHL---HLSSNPIELIREAVEKAKELGLTVSFDPGEME-VP 163 + E+ E + ++ H +P+ +I+ A + ++P + +P Sbjct: 123 TIYDPKQLCEIFPEGKEEEEYVVFQHEIPDPLSIIKWI--HANRPNFQIVYNPSPFKTMP 180 Query: 164 RDVEKELDILMMNE------------------------DEFKAKYGSL-----DRIKDVK 194 + + +D+L++NE D+F +Y + +++ + K Sbjct: 181 KKDWELVDLLVVNEIEGLQIVESVFDNELVEEIREKIKDDFLGEYRKICELLYEKLMNRK 240 Query: 195 AR-IAIATLNGGGALV-RDEKGEVHEVRGL-SAKAIDTTGGGDAFNAGFLYGFLSGWDVV 251 R I + TL G L E EV + + + +DTTG GD F G + G + Sbjct: 241 KRGIVVMTLGSRGVLFCSHESPEVQFLPAIQNVSVVDTTGAGDTFLGGLVTQLYQGETLS 300 Query: 252 NSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIA 284 + K L + LT+Q GA ++ +++K A Sbjct: 301 MAIKFSTLASSLTIQRKGAAESMPLYKDVQKDA 333 >pir||D64937 probable sugar kinase (EC 2.7.1.-) - Escherichia coli (strain K-12) >gi|1742883|dbj|BAA15563.1| (D90820) 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) (2-keto-3- Deoxygluconokinase) (3-deoxy-2-oxo-d-gluconate kinase) (Kdg kinase). [Escherichia coli] >gi|1742891|dbj|BAA15570.1| (D90821) 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) (2-keto-3- Deoxygluconokinase) (3-deoxy-2-oxo-d-gluconate kinase) (Kdg kinase). [Escherichia coli] >gi|1788071|gb|AAC74842.1| (AE000272) putative kinase [Escherichia coli K12] Length = 322 Score = 69.1 bits (166), Expect = 6e-11 Identities = 83/317 (26%), Positives = 142/317 (44%), Gaps = 43/317 (13%) Query: 4 DVICMGNLNYDI--------VFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLK 55 DVIC+G DI +F ++ +P + + GG A N AT +++LG + Sbjct: 12 DVICIGAAIVDIPLQPVSKNIFDVDSYP-------LERIAMTTGGDAINEATIISRLGHR 64 Query: 56 VGFIGAVGNDDFGRLHLEFFREIGVDTSGIKV-VNDATGIAVTMVKGEDKR-IVKYPGAN 113 + +G D G+ L+ R+ +D +K V+ T I V +V + +R V + Sbjct: 65 TALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLVTEDGERTFVTNRNGS 124 Query: 114 RWK----EVNTEYLKRARHLHLSS---NPI---ELIREAVEKAKELGLTVSFD---PGEM 160 WK +V+ +A+ L L+S +P+ + + E +AK + + D P Sbjct: 125 LWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGKALTEIFTQAKARQMIICADMIKPRLN 184 Query: 161 EVPRDVEKEL---DILMMNEDEFKAKYG--SLDRIKDVKARIAIATL----NGGGALVR- 210 E D+ + L D L N E K G +LD I D + T+ G ++ Sbjct: 185 ETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLACGVKTVVIKTGKDGCFIKR 244 Query: 211 -DEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVG 269 D +V V G++A IDT G GD F +GF+ L G ++ A+ A ++V VG Sbjct: 245 GDMTMKVPAVAGITA--IDTIGAGDNFASGFIAALLEGKNLRECARFANATAAISVLSVG 302 Query: 270 ARSAVRPLDEIKKIAQE 286 A + V+ ++++ +E Sbjct: 303 ATTGVKNRKLVEQLLEE 319 >gb|AAB51108.1| (U62329) fructokinase [Lycopersicon esculentum] >gi|2102693|gb|AAB57734.1| (U64818) fructokinase [Lycopersicon esculentum] Length = 328 Score = 69.1 bits (166), Expect = 6e-11 Identities = 67/246 (27%), Positives = 111/246 (44%), Gaps = 40/246 (16%) Query: 31 AKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVND 90 A G GG+ N A + +LG K F+G +G+D+FG + + GV GI Sbjct: 34 APGFLKAPGGAPANVAIAVTRLGGKSAFVGKLGDDEFGHMLAGILKTNGVQAEGINFDKG 93 Query: 91 A-TGIAVTMVKGEDKR---IVKYPGANRW---KEVNTEYLKRARHLHLSSNPIELIRE-- 141 A T +A ++ + +R + P A+ E+N + ++ A+ H S I LI E Sbjct: 94 ARTALAFVTLRADGEREFMFYRNPSADMLLTPAELNLDLIRSAKVFHYGS--ISLIVEPC 151 Query: 142 ------AVEKAKELGLTVSFDPGEMEVP-----RDVEKEL-------DILMMNEDEFKAK 183 A+E AKE G +S+DP + +P + +K++ D++ +++ E + Sbjct: 152 RAAHMKAMEVAKEAGALLSYDP-NLRLPLWPSAEEAKKQIKSIWDSADVIKVSDVELEFL 210 Query: 184 YGSLDRIKDVKA--------RIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDA 235 GS ++I D A ++ + TL G +K V G K +DTTG GD+ Sbjct: 211 TGS-NKIDDESAMSLWHPNLKLLLVTLGEKGCNYYTKKFH-GTVGGFHVKTVDTTGAGDS 268 Query: 236 FNAGFL 241 F L Sbjct: 269 FVGALL 274 >sp|P77493|YDJH_ECOLI HYPOTHETICAL SUGAR KINASE IN ANSA-GAPA INTERGENIC REGION Length = 315 Score = 69.1 bits (166), Expect = 6e-11 Identities = 83/317 (26%), Positives = 142/317 (44%), Gaps = 43/317 (13%) Query: 4 DVICMGNLNYDI--------VFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLK 55 DVIC+G DI +F ++ +P + + GG A N AT +++LG + Sbjct: 5 DVICIGAAIVDIPLQPVSKNIFDVDSYP-------LERIAMTTGGDAINEATIISRLGHR 57 Query: 56 VGFIGAVGNDDFGRLHLEFFREIGVDTSGIKV-VNDATGIAVTMVKGEDKR-IVKYPGAN 113 + +G D G+ L+ R+ +D +K V+ T I V +V + +R V + Sbjct: 58 TALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLVTEDGERTFVTNRNGS 117 Query: 114 RWK----EVNTEYLKRARHLHLSS---NPI---ELIREAVEKAKELGLTVSFD---PGEM 160 WK +V+ +A+ L L+S +P+ + + E +AK + + D P Sbjct: 118 LWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGKALTEIFTQAKARQMIICADMIKPRLN 177 Query: 161 EVPRDVEKEL---DILMMNEDEFKAKYG--SLDRIKDVKARIAIATL----NGGGALVR- 210 E D+ + L D L N E K G +LD I D + T+ G ++ Sbjct: 178 ETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLACGVKTVVIKTGKDGCFIKR 237 Query: 211 -DEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQEVG 269 D +V V G++A IDT G GD F +GF+ L G ++ A+ A ++V VG Sbjct: 238 GDMTMKVPAVAGITA--IDTIGAGDNFASGFIAALLEGKNLRECARFANATAAISVLSVG 295 Query: 270 ARSAVRPLDEIKKIAQE 286 A + V+ ++++ +E Sbjct: 296 ATTGVKNRKLVEQLLEE 312 >pir||A82433 fructokinase VCA0656 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9658072|gb|AAF96557.1| (AE004395) fructokinase [Vibrio cholerae] Length = 323 Score = 69.1 bits (166), Expect = 6e-11 Identities = 69/248 (27%), Positives = 108/248 (42%), Gaps = 33/248 (13%) Query: 39 GGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKV--VNDATGIAV 96 GG+ N A +A+L + F G VGND FGR + + VD + V+ + + V Sbjct: 44 GGAPANVAVAIARLCGRSAFFGRVGNDPFGRFMQQTLTDEQVDCQHLYFDPVHRTSTVVV 103 Query: 97 TMVKGEDKRI--VKYPGANRWKEVNT-EYLKRARHLHLSSNPIELIRE--------AVEK 145 + + ++ + P A+++ +++ + LH+ S I L + A+ + Sbjct: 104 DLDEHGERSFTFMVKPSADQFLQLSDIPSFQNGEWLHVCS--IALANQPSRSSTFAAIAQ 161 Query: 146 AKELGLTVSFDPGEMEVPRDVEKEL-----------DILMMNEDEFKAKYGS------LD 188 KE+G VSFDP E +EL D++ +E+E + G+ L Sbjct: 162 MKEVGGYVSFDPNLREEVWSEPQELQATVMRAVGLADVVKFSEEELQFLTGTQSIEEGLQ 221 Query: 189 RIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGW 248 I D + + + TL GALV V G + K IDTTG GDAF G LY Sbjct: 222 AIADFQIPLVVVTLGAKGALVVTPNSR-QIVSGKAVKPIDTTGAGDAFVGGLLYRLSVAQ 280 Query: 249 DVVNSAKL 256 D N A + Sbjct: 281 DWHNQATI 288 >gb|AAK43293.1| Fructokinase [Sulfolobus solfataricus] Length = 313 Score = 68.7 bits (165), Expect = 8e-11 Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 32/282 (11%) Query: 38 LGGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVNDA-TGIAV 96 + GS N + + L I VGND+FG+ +E+ R G+DTS IKV N++ TGI Sbjct: 32 VAGSELNFCIAVVRNHLSCSLIARVGNDEFGKNIIEYSRAQGIDTSHIKVDNESFTGIYF 91 Query: 97 TM------VKGEDKRIVKYPGANRW--KEVNTEYLKRARHLH-------LSSNPIELIRE 141 +K E K +R +++N Y++ +R +H +S N E + + Sbjct: 92 IQRGYPIPMKSELVYYRKGSAGSRLSPEDINENYVRNSRLVHSTGITLAISDNAKEAVIK 151 Query: 142 AVEKAKELGLTVSFDP---GEMEVPRDV------EKELDILMMNEDEFKAKYGSLD---- 188 A E AK L + P +E ++ + ++++L+ + D+ K D Sbjct: 152 AFELAKSRSLDTNIRPKLWSSLEKAKETILSILKKYDIEVLITDPDDTKILLDVTDPDEA 211 Query: 189 --RIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLS 246 + K++ ++ + L GA+ + + + D TG GDA F+ +L Sbjct: 212 YRKYKELGVKVLLYKLGSKGAIAYKDNVKAFK-DAYKVPVEDPTGAGDAMAGTFVSLYLQ 270 Query: 247 GWDVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIKKIAQELK 288 G D+ S G+ + L + G L++ ++ E K Sbjct: 271 GKDIEYSLAHGIAASTLVITVRGDNELTPTLEDAERFLNEFK 312 >sp|P37829|SCRK_SOLTU FRUCTOKINASE >gi|626018|pir||S39997 fructokinase (EC 2.7.1.4) - potato >gi|297015|emb|CAA78283.1| (Z12823) fructokinase [Solanum tuberosum] >gi|1095321|prf||2108342A fructokinase [Solanum tuberosum] Length = 319 Score = 68.7 bits (165), Expect = 8e-11 Identities = 65/235 (27%), Positives = 104/235 (43%), Gaps = 28/235 (11%) Query: 31 AKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGIKVVND 90 A G GG+ N A + +LG K F+G +G+D+FG + + GV GI Sbjct: 35 APGFLKAPGGAPANVAIAVTRLGGKSAFVGKLGDDEFGHMLAGILKTNGVQADGINFDKG 94 Query: 91 A-TGIAVTMVKGEDKR---IVKYPGANRW---KEVNTEYLKRARHLHLSSNPIELIRE-- 141 A T +A ++ + +R + P A+ E+N + ++ A+ H S I LI E Sbjct: 95 ARTALAFVTLRADGEREFMFYRNPSADMLLTPDELNLDLIRSAKVFHYGS--ISLIVEPC 152 Query: 142 ------AVEKAKELGLTVSFDPG-EMEVPRDVEKELDILMMNEDEFKAKYGSLDRIKDVK 194 A+E AKE G +S+DP + + + + +++ E + GS D+I D Sbjct: 153 RSAHLKAMEVAKEAGALLSYDPNLRLPLWSSEAEARKAIKVSDVELEFLTGS-DKIDDES 211 Query: 195 A--------RIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFL 241 A ++ + TL G +K V G K +DTTG GD+F L Sbjct: 212 AMSLWHPNLKLLLVTLGEKGCNYYTKKFH-GSVGGFHVKTVDTTGAGDSFVGALL 265 >sp|O34768|YDJE_BACSU HYPOTHETICAL SUGAR KINASE IN GUTA-COTA INTERGENIC REGION >gi|7434222|pir||A69789 fructokinase homolog ydjE - Bacillus subtilis >gi|2522009|dbj|BAA22760.1| (AB007638) sugar transport protein [Bacillus subtilis] >gi|2632930|emb|CAB12436.1| (Z99107) similar to fructokinase [Bacillus subtilis] Length = 320 Score = 68.7 bits (165), Expect = 8e-11 Identities = 86/317 (27%), Positives = 134/317 (42%), Gaps = 47/317 (14%) Query: 5 VICMGNLNYDIVFLMEKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAVGN 64 V+C+G L D F + + E + GG+ N + +AKLG F G VG Sbjct: 6 VVCIGELLIDF-FCTDVDVDLME---GRQFLKSAGGAPANVSAAIAKLGGDAAFSGKVGK 61 Query: 65 DDFGRLHLEFFREIGVDTSGIKVVNDA-TGIAVTMVKGEDKR-IVKYPGAN---RWKEVN 119 D FG + VDTS + + A T +A +K +R V GA+ ++++ Sbjct: 62 DPFGYFLKRTLDAVHVDTSMLVMDEKAPTTLAFVSLKQNGERDFVFNRGADALFTLEDID 121 Query: 120 TEYLKRARHLH------LSSNPI-ELIREAVEKAKELGLTVSFDPGEME----------- 161 E L A+ LH L S+P + AK+ G +SFDP E Sbjct: 122 QEKLNEAKILHFGSATALLSDPFCSAYLRLMSIAKDNGQFISFDPNYREDLWRGRVSEFV 181 Query: 162 -VPRDVEKELDILMMNEDEFKAKYGSLDRIK------DVKARIAIATLNGGGALVRDEKG 214 V + D + ++++E + G D K ++ A I TL G L+ + K Sbjct: 182 SVAKKAIAVSDFVKVSDEELEIISGVKDHEKGVAILHEIGANIVAVTLGKSGTLLSNGK- 240 Query: 215 EVHEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNS-----AKLGMLLAY------L 263 + + + +ID+TG GDAF LY L+ D + S KL ++A+ L Sbjct: 241 DREIIPSIPVTSIDSTGAGDAFVGAALYQ-LANTDQIQSVDADFVKLREIVAFANKVGAL 299 Query: 264 TVQEVGARSAVRPLDEI 280 ++GA A+ LDEI Sbjct: 300 VCTKIGAIDALPSLDEI 316 >pir||H72394 fructokinase - Thermotoga maritima (strain MSB8) >gi|4980795|gb|AAD35384.1|AE001711_7 (AE001711) fructokinase [Thermotoga maritima] Length = 315 Score = 68.7 bits (165), Expect = 8e-11 Identities = 73/283 (25%), Positives = 120/283 (41%), Gaps = 48/283 (16%) Query: 39 GGSAGNTATWLAKLGLKVGFIGAVGNDDFGRLHLEFFREIGVDTSGI-----------KV 87 GGS N A L +LG +V F+G +G D F LE ++ G+DT+ I V Sbjct: 33 GGSPLNVAVALKRLGREVSFLGKLGGDQFSEFLLEVMKKEGIDTTHIIFDSSCKTTLAFV 92 Query: 88 VNDATG---IAVTMVKGEDKRIVKYPGANRWKEVNTEYLKRA-RHLHLSSNPIELIREAV 143 DA G K D + R +EVN + + + H+ S +E R A Sbjct: 93 ARDAQGNPDFVFFREKPADTNL-------RPEEVNIDPAQFSFLHIGSYSLAVEPSRSAY 145 Query: 144 EKAKEL----GLTVSFDPGE-----------MEVPRDVEKELDILMMNEDEFKAKY---- 184 K E G VS+DP ++ ++ ++DI+ +++ + + + Sbjct: 146 LKVMETFLEEGKPVSYDPNVRPSLIEDRNTFVKDFLEISSKVDIVKLSDKDLEYIFQEDL 205 Query: 185 -GSLDRIKDVKARIAIATLNGGGALVRDEKGEVHEVRGLSAKAIDTTGGGDAFNAGFLYG 243 ++D+I + + T+ G LV+ KGE V K +D TG GD+F A ++ Sbjct: 206 ETAVDKIPIKENGLLFVTMGERGCLVK-FKGEKRMVPSFKVKPVDATGCGDSFTAAVIHK 264 Query: 244 FLSGW-----DVVNSAKLGMLLAYLTVQEVGARSAVRPLDEIK 281 +L D V K +A + + VG A+ LDE++ Sbjct: 265 YLEKTPETIEDAVEIGKFANAVAAIVITRVGGVDAMPVLDEVE 307 >pir||D75288 carbohydrate kinase, PfkB family - Deinococcus radiodurans (strain R1) >gi|6460123|gb|AAF11859.1|AE002063_2 (AE002063) carbohydrate kinase, PfkB family [Deinococcus radiodurans] Length = 383 Score = 68.7 bits (165), Expect = 8e-11 Identities = 80/292 (27%), Positives = 116/292 (39%), Gaps = 35/292 (11%) Query: 5 VICMGNLNYDIVFLM--EKFPGIHEKVNAKGVFTGLGGSAGNTATWLAKLGLKVGFIGAV 62 V+ +G N D+ + E PG N GG A N A LA+LG+ + AV Sbjct: 76 VVVVGGANMDLKARVRGEAVPGTS---NPGVTSQSPGGVARNVAENLARLGVSAALVSAV 132 Query: 63 GNDDFGRLHLEFFREIGVDTSGIKVVNDATGIAVTMVKGEDKRIVKYPGANRWKEVNTEY 122 G D G + L GVD SG+ V+ A + T V G ++ A E T Sbjct: 133 GPDSLGDVLLRETEAAGVDVSGVLRVSGAATGSYTAVLGAGGELLLAVAAMDVMEHLTPA 192 Query: 123 LKRARHLHL---------SSNPIELIREAVEKAKELGLTVSFDPGEMEVPRDVEKELDI- 172 R L + P + + + A E G+ V ++P + VP+ + Sbjct: 193 ALRGLRASLRGAAWVVADGNLPADTLPTLLALAAETGVRVVYEP--VSVPKAARLRPALA 250 Query: 173 -------LMMNEDEFKAKYGSLDRIKDVKARIAIATLNGGGALV----RDEKGEV----- 216 + N E A G R A L+ GA + R E+G V Sbjct: 251 AGHVPYAVTPNLAELAALVGREVADSPAAIREAALELHALGAELVWVRRGERGSVLSLPD 310 Query: 217 --HEVRGLSAKAIDTTGGGDAFNAGFLYGFLSGWDVVNSAKLGMLLAYLTVQ 266 HE+ L A +D TG GDA A FL G ++G +++A+ G A LTV+ Sbjct: 311 ESHELPALPAAVVDVTGAGDAMLAAFLAGLVAGLTPLHAAREGHAAAALTVE 362 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.319 0.140 0.400 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 109837956 Number of Sequences: 2977 Number of extensions: 4716196 Number of successful extensions: 13280 Number of sequences better than 1.0e-10: 60 Number of HSP's better than 0.0 without gapping: 4 Number of HSP's successfully gapped in prelim test: 56 Number of HSP's that attempted gapping in prelim test: 13192 Number of HSP's gapped (non-prelim): 60 length of query: 293 length of database: 189,106,746 effective HSP length: 55 effective length of query: 238 effective length of database: 156,189,961 effective search space: 37173210718 effective search space used: 37173210718 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 165 (68.7 bits)