BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0284 (PAB0284) DE:Hypothetical protein
         (197 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75159 hypothetical protein PAB0284 - Pyrococcus abyssi (st...   386  e-106
pir||F71181 hypothetical protein PH1731 - Pyrococcus horikoshii ...   310  7e-84
sp|Q58338|Y928_METJA HYPOTHETICAL PROTEIN MJ0928 >gi|2129071|pir...   141  4e-33
pir||F69043 conserved hypothetical protein MTH1329 - Methanobact...   139  2e-32
gi|11499373 protoporphyrinogen oxidase (hemK) [Archaeoglobus ful...   116  2e-25
gb|AAG19542.1| (AE005044) protoporphyrinogen oxidase; HemK [Halo...   101  5e-21
emb|CAC11261.1| (AL445063) N-methyl-transferase related protein ...    92  6e-18
pir||D75544 hemK protein - Deinococcus radiodurans (strain R1) >...    89  3e-17
gb|AAK41043.1| Conserved hypothetical protein [Sulfolobus solfat...    83  3e-15
emb|CAB57555.1| (Y18930) hypothetical protein [Sulfolobus solfat...    83  3e-15
emb|CAB61553.2| (AL133171) putative methyltransferase [Streptomy...    82  6e-15
pir||T31966 hypothetical protein C33C12.9 - Caenorhabditis elega...    80  1e-14
sp|P57269|HEMK_BUCAI HEMK PROTEIN HOMOLOG >gi|10038854|dbj|BAB12...    79  4e-14
pir||A83063 probable methyl transferase PA4664 [imported] - Pseu...    78  9e-14
gi|11526159 putative N6-DNA-methyltransferase [Homo sapiens] >gi...    76  4e-13
sp|P37186|HEMK_ECOLI HEMK PROTEIN >gi|2126016|pir||I83570 hemK p...    75  6e-13
gi|7019463 putative N6-DNA-methyltransferase [Homo sapiens] >gi|...    75  8e-13
gi|6320344 Ydr140wp [Saccharomyces cerevisiae] >gi|1077536|pir||...    74  1e-12
pir||B72640 hypothetical protein APE0554 - Aeropyrum pernix (str...    74  1e-12
gb|AAF73543.1| (AE002297) modification methylase, HemK family [C...    74  1e-12
sp|O66506|HEMK_AQUAE HEMK PROTEIN HOMOLOG >gi|7521589|pir||G7030...    73  3e-12
pir||E70124 protoporphyrinogen oxidase homolog - Lyme disease sp...    72  5e-12
pir||A82109 hemK protein VC2178 [imported] - Vibrio cholerae (gr...    72  5e-12
pir||G81952 HemK protein NMA0369 [imported] - Neisseria meningit...    71  1e-11
sp|P45253|HEMK_HAEIN HEMK PROTEIN HOMOLOG >gi|1075189|pir||H6412...    70  2e-11
pir||C71566 probable protoporphyrinogen oxidase - Chlamydia trac...    70  2e-11
pir||G82671 protoporphyrinogen oxidase XF1512 [imported] - Xylel...    70  2e-11
pir||G72369 hemK protein - Thermotoga maritima (strain MSB8) >gi...    70  2e-11
dbj|BAB10283.1| (AB008266) gene_id:MHJ24.13~similar to unknown p...    70  2e-11
pir||E81010 hemK protein NMB2065 [imported] - Neisseria meningit...    69  3e-11
dbj|BAB03843.1| (AP001507) unknown conserved protein [Bacillus h...    68  6e-11

>pir||C75159 hypothetical protein PAB0284 - Pyrococcus abyssi (strain Orsay)
           >gi|5457864|emb|CAB49354.1| (AJ248284) hypothetical
           protein [Pyrococcus abyssi]
           Length = 197
           
 Score =  386 bits (980), Expect = e-106
 Identities = 197/197 (100%), Positives = 197/197 (100%)

Query: 1   MAIHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKKAKF 60
           MAIHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKKAKF
Sbjct: 1   MAIHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKKAKF 60

Query: 61  VVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDDVKDEI 120
           VVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDDVKDEI
Sbjct: 61  VVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDDVKDEI 120

Query: 121 DLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFSTRIVKKE 180
           DLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFSTRIVKKE
Sbjct: 121 DLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFSTRIVKKE 180

Query: 181 RFFFEELYVMRAELSSR 197
           RFFFEELYVMRAELSSR
Sbjct: 181 RFFFEELYVMRAELSSR 197


>pir||F71181 hypothetical protein PH1731 - Pyrococcus horikoshii
           >gi|3258162|dbj|BAA30845.1| (AP000007) 198aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 198
           
 Score =  310 bits (786), Expect = 7e-84
 Identities = 148/197 (75%), Positives = 180/197 (91%)

Query: 1   MAIHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKKAKF 60
           MAI+YNGL+IE  E VYEPAEDTFLLAE+LL+EV+ DDIVLDVGTG+GILALLAA++A+F
Sbjct: 1   MAIYYNGLKIESNEEVYEPAEDTFLLAESLLDEVKSDDIVLDVGTGTGILALLAARRARF 60

Query: 61  VVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDDVKDEI 120
           VVGLDINEKAI+LAW+NA++NGIKNVVF++SDLF N+RG F LI+FNPPYLPG+++KD++
Sbjct: 61  VVGLDINEKAINLAWKNAKINGIKNVVFILSDLFENIRGTFDLIVFNPPYLPGEEIKDKV 120

Query: 121 DLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFSTRIVKKE 180
           DLALIGGKTG EVI +FL  V+DYL   GRIL++YSSLTGL+V +AF+E+GFST IVK+ 
Sbjct: 121 DLALIGGKTGGEVISRFLGSVKDYLSSRGRILLIYSSLTGLDVEKAFKERGFSTSIVKRR 180

Query: 181 RFFFEELYVMRAELSSR 197
           RFFFEELYVM+AELSSR
Sbjct: 181 RFFFEELYVMKAELSSR 197


>sp|Q58338|Y928_METJA HYPOTHETICAL PROTEIN MJ0928 >gi|2129071|pir||H64415 hypothetical
           protein YDR140w homolog - Methanococcus jannaschii
           >gi|1591599|gb|AAB98930.1| (U67536) protoporphyrinogen
           oxidase (hemK) [Methanococcus jannaschii]
           Length = 197
           
 Score =  141 bits (353), Expect = 4e-33
 Identities = 81/197 (41%), Positives = 123/197 (62%), Gaps = 8/197 (4%)

Query: 1   MAIHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKK-AK 59
           M I   G+++++   VYEPAED+ LL + L++   +D  VL++G G+G++++  AKK AK
Sbjct: 1   MIIEIEGIKLKLHPEVYEPAEDSILLLKNLVDVKNKD--VLEIGVGTGLISIACAKKGAK 58

Query: 60  FVVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLP---GDDV 116
            +VG+DIN  A+ LA  NA+LN + N+ F  SDLF N+ GKF +ILFNPPYLP    + +
Sbjct: 59  KIVGVDINPYAVKLAKENAKLNNV-NISFFESDLFENVTGKFDVILFNPPYLPTSEDEKI 117

Query: 117 KDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTG-LNVREAFEEKGFSTR 175
              ++ A  GGK G E++ +F+ ++ +YL  GG + I+ SSLTG        +  GF   
Sbjct: 118 DSYLNFAFDGGKDGREILDRFIYELPNYLKKGGVVQILQSSLTGEKETINKLKPLGFKVE 177

Query: 176 IVKKERFFFEELYVMRA 192
           I  + +  FEEL V+ A
Sbjct: 178 ISARLKVPFEELMVINA 194


>pir||F69043 conserved hypothetical protein MTH1329 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622435|gb|AAB85807.1| (AE000896) methyltransferase
           related protein [Methanobacterium thermoautotrophicum]
           Length = 196
           
 Score =  139 bits (348), Expect = 2e-32
 Identities = 86/195 (44%), Positives = 122/195 (62%), Gaps = 9/195 (4%)

Query: 3   IHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKKAKFVV 62
           I Y  ++I+  E+VYEPAEDTFLLA+ L  +VRE D VL++GTG+G++A+ A++K   V 
Sbjct: 4   IRYGEIKIKTCENVYEPAEDTFLLADNL--DVREGDRVLEIGTGTGLVAIRASEKGD-VT 60

Query: 63  GLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRG-KFTLILFNPPYLP--GDDVK-D 118
             D+N  A+     NA +NG++  V +  DLF  + G KF +ILFN PYLP  GDD   D
Sbjct: 61  ATDVNPAAVKCTQENAIINGVELRV-LQGDLFDPVEGEKFDVILFNTPYLPATGDDATGD 119

Query: 119 EIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGL-NVREAFEEKGFSTRIV 177
            +DLA  GG  G  VI +FL +V  +L PGGR+ +V SSL+      +   + GF   + 
Sbjct: 120 VLDLAWNGGPDGRMVIDRFLDEVPAHLKPGGRVQLVQSSLSDTEKTLQKLADMGFDASVT 179

Query: 178 KKERFFFEELYVMRA 192
             ER+FFEE+ ++ A
Sbjct: 180 ASERYFFEEIVLITA 194


>gi|11499373 protoporphyrinogen oxidase (hemK) [Archaeoglobus fulgidus]
           >gi|6226464|sp|O28490|YH84_ARCFU HYPOTHETICAL PROTEIN
           AF1784 >gi|7483929|pir||G69472 protoporphyrinogen
           oxidase (hemK) homolog - Archaeoglobus fulgidus
           >gi|2648761|gb|AAB89463.1| (AE000979) protoporphyrinogen
           oxidase (hemK) [Archaeoglobus fulgidus]
           Length = 177
           
 Score =  116 bits (288), Expect = 2e-25
 Identities = 67/179 (37%), Positives = 107/179 (59%), Gaps = 10/179 (5%)

Query: 16  VYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKKAKFVVGLDINEKAIDLAW 75
           +YEPAED+ LL EA L E++ DD V++VG GSG +A     K K ++  DI+  A     
Sbjct: 2   IYEPAEDSELLLEAALRELKPDDEVIEVGAGSGFVAERLKGKCKCILTTDISPFAAMELR 61

Query: 76  RNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDDVK---DEIDLALIGGKTGSE 132
           R       K +  V++D+ + +R KF+L+LFNPPY+  +D     D +D+A+ GGK G +
Sbjct: 62  R-------KGLDVVMTDIAKGIRKKFSLVLFNPPYVELEDELRRGDWLDVAIDGGKKGVK 114

Query: 133 VILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFSTRIVKKERFFFEELYVMR 191
           VI KFL  +++ +   GR +++ SS    +V +  +E+GF   IV +   FFE+L+ ++
Sbjct: 115 VIKKFLDSLDEIMAERGRAILIASSQNEPDVFDLIDERGFRYEIVGERGLFFEKLFAIK 173


>gb|AAG19542.1| (AE005044) protoporphyrinogen oxidase; HemK [Halobacterium sp.
           NRC-1]
           Length = 191
           
 Score =  101 bits (250), Expect = 5e-21
 Identities = 73/182 (40%), Positives = 103/182 (56%), Gaps = 13/182 (7%)

Query: 16  VYEPAEDTFLLAEALLEEVREDDI-VLDVGTGSG-ILALLAAKKAKFVVGLDINEKAIDL 73
           VY+PAEDT LLA A + E+ +    VLDVGTGSG + A +  +    VVG D+N  A+  
Sbjct: 14  VYQPAEDTHLLATAAVGELDDPYARVLDVGTGSGYVAATVRDETGADVVGTDLNPFAVRQ 73

Query: 74  AWRNAQLNGIKNVVFVVSDLFRNLRGK-FTLILFNPPYLPG-DDVKDE-IDLALIGGKTG 130
           A         + V  V  DL    R   F  ++FNPPYLP  DD +D+ +D+AL GG TG
Sbjct: 74  A-------ADRGVPVVRGDLVAPFRDDAFDAVVFNPPYLPREDDTRDDWMDVALSGGDTG 126

Query: 131 SEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFE-EKGFSTRIVKKERFFFEELYV 189
             VI  F   V   L P G ++++ S+LTG++   A+  ++GFS   + +E F FE L V
Sbjct: 127 RRVIESFFDAVGRVLAPDGVVIMLVSTLTGVDEVAAYAGDRGFSAAAISEESFPFETLTV 186

Query: 190 MR 191
           ++
Sbjct: 187 LK 188


>emb|CAC11261.1| (AL445063) N-methyl-transferase related protein [Thermoplasma
           acidophilum]
           Length = 182
           
 Score = 91.7 bits (224), Expect = 6e-18
 Identities = 64/194 (32%), Positives = 104/194 (52%), Gaps = 12/194 (6%)

Query: 3   IHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKKAKFVV 62
           +HY  L I   + VY P+ED+FL+    +E        +++G G+GI+++   K+   + 
Sbjct: 1   MHYCDLDIAECDGVYPPSEDSFLI----IEYASCSGKAIEIGCGTGIVSICFLKRGCDIE 56

Query: 63  GLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDDVKDEIDL 122
            +DI++ A++ A  NA  NG+   V+  SDLF  + G +  ILFN PY+P   V+ E D 
Sbjct: 57  AVDISDLAVECAKDNASRNGLTLKVY-RSDLFSGVSGTYDTILFNAPYIP---VEGE-DA 111

Query: 123 ALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFSTRIVKKERF 182
           +  GG+   EV+ +FL    ++L   G+I IV S LT  +    F   G+   I+KK  F
Sbjct: 112 SWSGGR-NLEVVSRFLGQAREHLSASGQIYIVLSDLT--DNEGMFRMMGYDYFIIKKISF 168

Query: 183 FFEELYVMRAELSS 196
            FE + + +  L +
Sbjct: 169 EFEAIVLYKLTLKA 182


>pir||D75544 hemK protein - Deinococcus radiodurans (strain R1)
           >gi|6457913|gb|AAF09827.1|AE001885_11 (AE001885) hemK
           protein [Deinococcus radiodurans]
           Length = 278
           
 Score = 89.3 bits (218), Expect = 3e-17
 Identities = 61/162 (37%), Positives = 87/162 (53%), Gaps = 12/162 (7%)

Query: 3   IHYNGLRIEVEESVYEPAEDTFLLAEALLEEVR--EDDIVLDVGTGSGILAL--LAAKKA 58
           + + G+R+  +     P  +T  L    LEE+R  E   VLDVGTG+G LAL   AA   
Sbjct: 77  VEWGGVRLTSDARALVPRPETEWLLHLALEELRRVEKPRVLDVGTGTGALALGLKAAIPQ 136

Query: 59  KFVVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDD--- 115
             V   D++ +A+ LA  NA L+G+ +V FV   L   L G F LI+ NPPYLP  D   
Sbjct: 137 AEVTATDLSPEALSLARENAALSGL-DVKFVEGSLLAGLSGPFNLIVSNPPYLPTADRAT 195

Query: 116 ----VKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILI 153
               V+ + DLAL  G+ G +V    +++    L+PGG +L+
Sbjct: 196 ADPEVRHDPDLALYAGEDGLDVARPLVAEAAAALVPGGALLL 237


>gb|AAK41043.1| Conserved hypothetical protein [Sulfolobus solfataricus]
           Length = 207
           
 Score = 82.7 bits (201), Expect = 3e-15
 Identities = 56/162 (34%), Positives = 88/162 (53%), Gaps = 12/162 (7%)

Query: 3   IHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKKAKFVV 62
           I + G+R+ + +  YEP++DT +L   L   V + D VLD+G+GSGIL + +      VV
Sbjct: 7   IEFRGIRLCLNDQTYEPSDDTDILLSLL--RVGKGDKVLDMGSGSGILGIWSLMMGGKVV 64

Query: 63  GLDINEKAIDLAWRNAQLNGIKNVV----FVVSDLFRNLRG-KFTLILFNPPYLPGDDVK 117
            +DIN  A      + ++N + N       +  DL   LR   F + +FNPPYLP ++  
Sbjct: 65  FVDINPYATLSTLCSLKVNNLYNTPNYYGVLNCDLLSCLRKYDFDVAIFNPPYLPVEEYN 124

Query: 118 DEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLT 159
           + I+ +  GG  GS+V++ FL  V+       RI  +YSSL+
Sbjct: 125 EWIEYSWSGGNDGSKVLIDFLKTVK-----ANRIYTLYSSLS 161


>emb|CAB57555.1| (Y18930) hypothetical protein [Sulfolobus solfataricus]
           Length = 207
           
 Score = 82.7 bits (201), Expect = 3e-15
 Identities = 56/162 (34%), Positives = 88/162 (53%), Gaps = 12/162 (7%)

Query: 3   IHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAAKKAKFVV 62
           I + G+R+ + +  YEP++DT +L   L   V + D VLD+G+GSGIL + +      VV
Sbjct: 7   IEFRGIRLCLNDQTYEPSDDTDILLSLL--RVGKGDKVLDMGSGSGILGIWSLMMGGKVV 64

Query: 63  GLDINEKAIDLAWRNAQLNGIKNVV----FVVSDLFRNLRG-KFTLILFNPPYLPGDDVK 117
            +DIN  A      + ++N + N       +  DL   LR   F + +FNPPYLP ++  
Sbjct: 65  FVDINPYATLSTLCSLKVNNLYNTPNYYGVLNCDLLSCLRKYDFDVAIFNPPYLPVEEYN 124

Query: 118 DEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLT 159
           + I+ +  GG  GS+V++ FL  V+       RI  +YSSL+
Sbjct: 125 EWIEYSWSGGNDGSKVLIDFLKTVK-----ANRIYTLYSSLS 161


>emb|CAB61553.2| (AL133171) putative methyltransferase [Streptomyces coelicolor
           A3(2)]
           Length = 220
           
 Score = 81.5 bits (198), Expect = 6e-15
 Identities = 72/208 (34%), Positives = 99/208 (46%), Gaps = 30/208 (14%)

Query: 16  VYEPAEDTFLLAEALLEE-VREDDIVLDVGTGSGILALLAAKKAKFVVGLDINEKAIDLA 74
           VY P EDT LLA AL +E +     VLDVGTGSG LAL AA +   V  +D++ +A+  A
Sbjct: 12  VYAPQEDTALLAGALSDESLPPGAAVLDVGTGSGALALAAAGRGGRVTAVDVSWRAVCAA 71

Query: 75  WRNAQLNGIKNVVFVVSDLFRNLRGK-FTLILFNPPYLPGDDVKDE---IDLALIGGKTG 130
             NA   G++ +     +LF  +RG+ F L+L NPPY+P             A   G  G
Sbjct: 72  RLNAVRAGLR-IRVRHGNLFTPVRGESFDLVLANPPYVPAPATGRRPRGAARAWDAGHDG 130

Query: 131 SEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREA-FEEKGFSTRIVKKERFFF----- 184
             V+ +   +V   L PGG +L+V S+L+     EA   E G    + ++ R  F     
Sbjct: 131 RMVLDRICLEVPRLLRPGGVLLLVQSALSDPARTEALLREAGLKAAVTRRRRIAFGPVVR 190

Query: 185 ------------------EELYVMRAEL 194
                             EEL V+RAEL
Sbjct: 191 GRERWLRQRGLLSLADYEEELVVVRAEL 218


>pir||T31966 hypothetical protein C33C12.9 - Caenorhabditis elegans
           >gi|2315591|gb|AAB66061.1| (AF016662) C33C12.9 gene
           product [Caenorhabditis elegans]
           Length = 262
           
 Score = 80.4 bits (195), Expect = 1e-14
 Identities = 64/216 (29%), Positives = 100/216 (45%), Gaps = 41/216 (18%)

Query: 16  VYEPAEDTFLLAEAL---LEEVREDD--IVLDVGTGSGILALLAAKKAK---FVVGLDIN 67
           VYEPAEDTFLL +A+   ++E+R  D  +VL++G GSG+++    +        V  D+N
Sbjct: 31  VYEPAEDTFLLIDAIEKDIKEIRSRDPKLVLEIGCGSGVVSTFVNQALGGNVTSVATDLN 90

Query: 68  EKAIDLAWRNAQLNGIKNVVFVVSDLF---RNLRGKF----------------------- 101
             A+D+    A+LN IK +  V +DLF    NL GK                        
Sbjct: 91  PHALDVTLETAKLNDIK-IDVVRTDLFAGLENLLGKVGKVREKFEKLKKNHKSRRLLKKI 149

Query: 102 -----TLILFNPPYLPGDDV-KDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVY 155
                 ++LFNPPY+P D+  K  I+L   GG+TG   + + L  V + L P G   +V 
Sbjct: 150 PRKLVDVLLFNPPYVPTDEEPKSNIELTYAGGRTGRSTLDRLLPRVPELLSPRGVFYLVA 209

Query: 156 SSLTGLNVREAFEEKGFSTRIVKKERFFFEELYVMR 191
                +        +  +  +  + R   E LY+++
Sbjct: 210 LHSNDIPALLKEHSEQMTVSVSMERRCGIEHLYILK 245


>sp|P57269|HEMK_BUCAI HEMK PROTEIN HOMOLOG >gi|10038854|dbj|BAB12889.1| (AP001118) hemK
           protein [Buchnera sp. APS]
           Length = 277
           
 Score = 78.8 bits (191), Expect = 4e-14
 Identities = 53/164 (32%), Positives = 87/164 (52%), Gaps = 10/164 (6%)

Query: 19  PAEDTFLLAEALLEEVREDDI-VLDVGTGSGILAL-LAAKKAKF-VVGLDINEKAIDLAW 75
           P  DT +L E  L +++ +   +LD+GTG G +AL LA+  + + ++G+D +E A+ +A 
Sbjct: 91  PRPDTEILVERALSKIKSNSACILDLGTGCGAIALALASINSNWNIIGIDKSENALAIAR 150

Query: 76  RNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDDVK-------DEIDLALIGGK 128
            NA     KNV F  SD F N++ KF +I+ NPPY+   ++K        E   ALI   
Sbjct: 151 INASKLNFKNVTFFFSDWFLNIKKKFNIIVSNPPYVSKKEIKFFKKDIFFEPLSALISDN 210

Query: 129 TGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGF 172
            G   I   + + + YL  GG ++I +     + V+  F++  F
Sbjct: 211 NGLSDIENIIKNSKHYLFYGGWLMIEHGWRQKVKVQYLFKKYNF 254


>pir||A83063 probable methyl transferase PA4664 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9950919|gb|AAG08051.1|AE004880_7 (AE004880) probable
           methyl transferase [Pseudomonas aeruginosa]
           Length = 276
           
 Score = 77.6 bits (188), Expect = 9e-14
 Identities = 61/177 (34%), Positives = 88/177 (49%), Gaps = 11/177 (6%)

Query: 8   LRIEVEESVYEPAEDTFLLAEALLEEVREDDI-VLDVGTGSGILALLAAKKAKF--VVGL 64
           L +EV      P  DT LL E  L  +  D   VLD+GTG+G +AL  A +     V  +
Sbjct: 79  LDLEVAPHTLIPRPDTELLVETALATLAADTATVLDLGTGTGAIALALASERPLWTVTAV 138

Query: 65  DINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGK-FTLILFNPPYLPGDD-------V 116
           D  E+A+ LA RN Q   ++NV    S  F  L G+ F +I+ NPPY+P  D       V
Sbjct: 139 DRVEEAVALAERNRQRLLLENVEVRRSHWFSALDGRRFRMIVGNPPYIPASDPHLSEGDV 198

Query: 117 KDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFS 173
           + E   AL+ G  G + I + ++    +LL  G +L+ +    G  VRE    +GF+
Sbjct: 199 RFEPKSALVAGSDGLDDIRQIVAQAPRHLLDEGWLLLEHGYDQGAAVRELLGARGFA 255


>gi|11526159 putative N6-DNA-methyltransferase [Homo sapiens]
           >gi|9988059|sp|Q9Y5N5|N6M1_HUMAN PUTATIVE
           N6-DNA-METHYLTRANSFERASE (PRED28 PROTEIN) (M.HSAHEMK2P)
           >gi|7717305|emb|CAB90428.1| (AL163248) putative
           N6-DNA-methyltransferase Accession No. AF139682 [Homo
           sapiens]
           Length = 214
           
 Score = 75.7 bits (183), Expect = 4e-13
 Identities = 57/153 (37%), Positives = 84/153 (54%), Gaps = 16/153 (10%)

Query: 16  VYEPAEDTFLLAEAL---LEEVREDDIVLDVGTGSGI----LALLAAKKAKFVVGLDINE 68
           VYEPAEDTFLL +AL     E+   +I L+VG+GSG+    LA +   +A ++   DIN 
Sbjct: 22  VYEPAEDTFLLLDALEAAAAELAGVEICLEVGSGSGVVSAFLASMIGPQALYMC-TDINP 80

Query: 69  KAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFT----LILFNPPYL---PGDDVKDEID 121
           +A       A+ N + ++  V++DL + L  + T    L++FNPPY+   P +     I+
Sbjct: 81  EAAACTLETARCNKV-HIQPVITDLVKGLLPRLTEKVDLLVFNPPYVVTPPQEVGSHGIE 139

Query: 122 LALIGGKTGSEVILKFLSDVEDYLLPGGRILIV 154
            A  GGK G EV+ +F   V D L P G   +V
Sbjct: 140 AAWAGGKNGREVMDRFFPLVPDLLSPKGLFYLV 172


>sp|P37186|HEMK_ECOLI HEMK PROTEIN >gi|2126016|pir||I83570 hemK protein (EC 1.3.3.-) -
           Escherichia coli >gi|968931|gb|AAC43438.1| (U18555)
           possible protoporphyrinogen oxidase [Escherichia coli]
           >gi|1651602|dbj|BAA36070.1| (D90756) Protoporphyrinogen
           oxidase (EC 1.3.3.4) hemK [Escherichia coli]
           >gi|1651610|dbj|BAA36080.1| (D90757) Protoporphyrinogen
           oxidase (EC 1.3.3.4) hemK [Escherichia coli]
           >gi|1787463|gb|AAC74296.1| (AE000219) possible
           protoporphyrinogen oxidase [Escherichia coli K12]
           Length = 277
           
 Score = 74.9 bits (181), Expect = 6e-13
 Identities = 58/176 (32%), Positives = 87/176 (48%), Gaps = 11/176 (6%)

Query: 8   LRIEVEESVYEPAEDTFLLAEALLEEVREDDI-VLDVGTGSGILALLAAKKAKF--VVGL 64
           L + V  +   P  DT  L E  L  + E    +LD+GTG+G +AL  A +     ++ +
Sbjct: 80  LPLFVSPATLIPRPDTECLVEQALARLPEQPCRILDLGTGTGAIALALASERPDCEIIAV 139

Query: 65  DINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRG-KFTLILFNPPY-------LPGDDV 116
           D    A+ LA RNAQ   IKN+  + SD F  L G +F +I+ NPPY       L   DV
Sbjct: 140 DRMPDAVSLAQRNAQHLAIKNIHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDV 199

Query: 117 KDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGF 172
           + E   AL+   +G   I+  +    + L+ GG +L+ +    G  VR+AF   G+
Sbjct: 200 RFEPLTALVAADSGMADIVHIIEQSRNALVSGGFLLLEHGWQQGEAVRQAFILAGY 255


>gi|7019463 putative N6-DNA-methyltransferase [Homo sapiens]
           >gi|5052364|gb|AAD38520.1|AF139682_1 (AF139682) putative
           N6-DNA-methyltransferase; N6AMT1 [Homo sapiens]
           Length = 214
           
 Score = 74.5 bits (180), Expect = 8e-13
 Identities = 56/153 (36%), Positives = 84/153 (54%), Gaps = 16/153 (10%)

Query: 16  VYEPAEDTFLLAEAL---LEEVREDDIVLDVGTGSGI----LALLAAKKAKFVVGLDINE 68
           VYEPAEDTFLL +AL     E+   +I L+VG+GSG+    LA +   +A ++   DIN 
Sbjct: 22  VYEPAEDTFLLLDALEAAAAELAGVEICLEVGSGSGVVSAFLASMIGPQALYMC-TDINP 80

Query: 69  KAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFT----LILFNPPYL---PGDDVKDEID 121
           +A       A+ N + ++  V++DL + L  + T    L++FNPPY+   P +     I+
Sbjct: 81  EAAACTLETARCNKV-HIQPVITDLVKGLLPRLTEKVDLLVFNPPYVVTPPQEVGSHGIE 139

Query: 122 LALIGGKTGSEVILKFLSDVEDYLLPGGRILIV 154
            A  GG+ G EV+ +F   V D L P G   +V
Sbjct: 140 AAWAGGRNGREVMDRFFPLVPDLLSPRGLFYLV 172


>gi|6320344 Ydr140wp [Saccharomyces cerevisiae] >gi|1077536|pir||S51868
           hypothetical protein YDR140w - yeast (Saccharomyces
           cerevisiae) >gi|665673|emb|CAA88222.1| (Z48179) unknown
           [Saccharomyces cerevisiae]
           Length = 221
           
 Score = 73.7 bits (178), Expect = 1e-12
 Identities = 53/169 (31%), Positives = 86/169 (50%), Gaps = 27/169 (15%)

Query: 14  ESVYEPAEDTFLLAEALLEEV--------REDDIVLDVGTGSGILAL------LAAKKAK 59
           + VYEPAED+FL+ + L +E             IV ++G+GSGI+        +  ++  
Sbjct: 12  DKVYEPAEDSFLILDCLEKEHDFLKQKFGNRLAIVCEIGSGSGIVTTFLMQNKIIPQENS 71

Query: 60  FVVGLDINEKAIDLAWRNAQLNGIKNVVFVV--SDLFRNLRG-KFTLILFNPPYLPGDDV 116
             + +DIN  A++     A+LN  K+    V  +DL  ++R  +  +++FNPPY+P + V
Sbjct: 72  IHLAVDINPWALEATLDTAKLNSCKSSFLEVIQADLNSSIRNNQVDVLIFNPPYVPAECV 131

Query: 117 KDE----------IDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVY 155
            D           +DLAL+GGK G  +  K L  +E  L P G   I++
Sbjct: 132 PDVPGSREEADQWLDLALLGGKDGMAITDKLLRQLEQILSPDGVAYILF 180


>pir||B72640 hypothetical protein APE0554 - Aeropyrum pernix (strain K1)
           >gi|5104207|dbj|BAA79522.1| (AP000060) 215aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 215
           
 Score = 73.7 bits (178), Expect = 1e-12
 Identities = 63/197 (31%), Positives = 90/197 (44%), Gaps = 23/197 (11%)

Query: 8   LRIEVEESVYEPAEDTFLLAEALLEEVREDDI---VLDVGTGSGILALLAAKK--AKFVV 62
           + + V    Y P++DT LL EA+    RE  +    LD+GTG+G LAL A +    + V 
Sbjct: 27  IAVYVNSCTYPPSDDTILLLEAMEALRREGRVYGSALDLGTGNGALALGAVEVLGVRRVA 86

Query: 63  GLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLP-------GDD 115
            +D    A       A+       +  V      L+G F + L NPPYLP       G  
Sbjct: 87  AVD----AYPCPALAARATLPPQALVAVCPYASCLKGGFDIALVNPPYLPEKPPPPGGQG 142

Query: 116 VKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFSTR 175
               +  A  G     E +++ + +    L   G +L VYSSL+ +  +E     GFSTR
Sbjct: 143 CSPTLSEAWAG-----EGVMRGMLEAAGRL--AGEVLTVYSSLSSVTPQEVLGAMGFSTR 195

Query: 176 IVKKERFFFEELYVMRA 192
           I+  ERFF E L V+ A
Sbjct: 196 ILASERFFMERLEVVHA 212


>gb|AAF73543.1| (AE002297) modification methylase, HemK family [Chlamydia
           muridarum]
           Length = 290
           
 Score = 73.7 bits (178), Expect = 1e-12
 Identities = 62/201 (30%), Positives = 95/201 (46%), Gaps = 18/201 (8%)

Query: 3   IHYNGLRIEVEESVYEPAEDTFLLAEAL---LEEVREDDIVLDVGTGSGILALLAAKKAK 59
           +H+ G+ ++V   V  P ++T +  E +   L+  +E  I  DV  GSG + L   K   
Sbjct: 73  VHFLGIELQVSPEVLIPRQETEIFVEKIIGYLQTHKEKKIFYDVCCGSGCIGLSVKKHCP 132

Query: 60  FV--VGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDD-- 115
            V  V  DI  +A+ +A  NA+ N +  V F+  DLF   R      + NPPYL   +  
Sbjct: 133 HVHVVLSDICSQALAVAKSNAKRNDLI-VDFLCGDLFEPFRIPADAFVCNPPYLSYKEFF 191

Query: 116 -VKDEIDL-----ALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEE 169
            V  E+       AL+GG +G E   +    +   L+PGG   +   S  G +V++ F +
Sbjct: 192 KVDPEVRCHEPWKALVGGVSGLEFYHRIAEHIHKILVPGGVGWLEIGSNQGESVKKIFRD 251

Query: 170 KGFSTRIVKK----ERFFFEE 186
           KG S  + K     +RFFF E
Sbjct: 252 KGISGCVFKDYAQLDRFFFLE 272


>sp|O66506|HEMK_AQUAE HEMK PROTEIN HOMOLOG >gi|7521589|pir||G70309 protoporphyrinogen
           oxidase - Aquifex aeolicus >gi|2982836|gb|AAC06458.1|
           (AE000673) protoporphyrinogen oxidase [Aquifex aeolicus]
           Length = 281
           
 Score = 72.6 bits (175), Expect = 3e-12
 Identities = 56/185 (30%), Positives = 96/185 (51%), Gaps = 13/185 (7%)

Query: 7   GLRIEVEESVYEPAEDTFLLAEALLEEVREDD--IVLDVGTGSGILAL-LAAKKAKFVV- 62
           G   +V++ V  P  +T +L E  LE + +D   +  ++G+G+G +++ L  ++ K V+ 
Sbjct: 82  GRVFKVKKGVLVPRPETEILIERTLELIPQDREMVGFELGSGTGCISINLLIERPKLVMY 141

Query: 63  GLDINEKAIDLAWRNAQLNGIKNVVFV-VSDLFRNLRG-KFTLILFNPPYLPG------- 113
             D+N  A++L   NA+L+ + + +FV + + F  ++G KF  I+ NPPY+P        
Sbjct: 142 ATDVNPDAVELTKENAKLHKVDDRLFVFLGNAFEPVKGMKFDFIVSNPPYIPENFWEILP 201

Query: 114 DDVKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFS 173
           ++VK E   +LIGGK G E       +   +L   G I +      G  V+E  E+K F 
Sbjct: 202 EEVKKEGYTSLIGGKKGWEFYELIAEEGTKHLKENGFIALEIGHDQGKVVKELLEKKCFK 261

Query: 174 TRIVK 178
             I K
Sbjct: 262 VNIFK 266


>pir||E70124 protoporphyrinogen oxidase homolog - Lyme disease spirochete
           >gi|2688095|gb|AAC66591.1| (AE001130) protoporphyrinogen
           oxidase, putative [Borrelia burgdorferi]
           Length = 286
           
 Score = 71.8 bits (173), Expect = 5e-12
 Identities = 53/180 (29%), Positives = 97/180 (53%), Gaps = 11/180 (6%)

Query: 5   YNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDI--VLDVGTGSGILAL-LAAKKAKFV 61
           + G+   + + V  P  DT  LAE  L +++++    +LD+  GSG + L +A    K V
Sbjct: 73  FMGIEFSLNKHVLIPRFDTECLAEEALIQIQQNGFKKILDLCCGSGCIGLSIAYYIRKKV 132

Query: 62  VGLDINEKAIDLAWRNAQLNGIKNVVFVV-SDLFRNLRGKFTLILFNPPYLPGDD----- 115
           +  DI+ KA+ +  +N +   ++  V ++ S+L + ++GK  +I+ NPPYL  ++     
Sbjct: 133 ILSDISTKALQIVEKNTKKLKLEKFVEIIHSNLLKCIKGKLDIIITNPPYLNKEELEIKN 192

Query: 116 -VKDEIDLALIG-GKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFS 173
            +K E   AL+G GK G  +  K L+  ++ L P G I+I  +     ++++   +KGFS
Sbjct: 193 KIKKEPTKALLGFGKDGLNISRKILNQAKEKLSPNGLIIIESAPWQIKSLKDFAIKKGFS 252


>pir||A82109 hemK protein VC2178 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9656732|gb|AAF95323.1| (AE004289) hemK
           protein [Vibrio cholerae]
           Length = 286
           
 Score = 71.8 bits (173), Expect = 5e-12
 Identities = 58/185 (31%), Positives = 86/185 (46%), Gaps = 12/185 (6%)

Query: 8   LRIEVEESVYEPAEDTFLLAEALLEEVRE-DDIVLDVGTGSGILALLAAKK--AKFVVGL 64
           L ++V  S   P  DT  L E  L++    D  +LD+GTG+G +AL  A +   + V G+
Sbjct: 84  LPLKVSPSTLIPRPDTERLVELALDKAALIDGELLDLGTGTGAIALALASELPTRQVTGI 143

Query: 65  DINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRG--KFTLILFNPPY-------LPGDD 115
           D+  +A +LA  NA    I N  F     F  L    KF LI+ NPPY       L   D
Sbjct: 144 DLRPEAAELARENATRLAIHNAQFFQGSWFSPLADGTKFALIVSNPPYIEENDPHLSLGD 203

Query: 116 VKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGFSTR 175
           V+ E   AL+  + G   I    +    +LL GG +L  +    G+ VR    + G+   
Sbjct: 204 VRFEPKSALVAAENGLADIRHISTHAPHFLLDGGWLLFEHGYDQGVAVRTILRDLGYQNI 263

Query: 176 IVKKE 180
           I +++
Sbjct: 264 ITEQD 268


>pir||G81952 HemK protein NMA0369 [imported] - Neisseria meningitidis  (group A
           strain Z2491) >gi|7379122|emb|CAB83670.1| (AL162753)
           HemK protein [Neisseria meningitidis Z2491]
           Length = 273
           
 Score = 70.6 bits (170), Expect = 1e-11
 Identities = 61/184 (33%), Positives = 85/184 (46%), Gaps = 13/184 (7%)

Query: 2   AIHYNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAA--KKAK 59
           A  + G R  V  SV  P  +T  L EA+L  + E+  V D+GTGSG +A+  A  +   
Sbjct: 67  AREFYGRRFTVNPSVLIPRPETEHLVEAVLARLPENGRVWDLGTGSGAVAVTVALERPDA 126

Query: 60  FVVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRN---LRGKFTLILFNPPYLP-GD- 114
           FV   DI+  A++ A +NA   G + V F     F       GK+ +I+ NPPY+  GD 
Sbjct: 127 FVRASDISPPALETARKNAADLGAR-VEFAYGSWFDTDMPSEGKWDIIVSNPPYIENGDK 185

Query: 115 -----DVKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEE 169
                D++ E  +AL     G   I        D L  GG +L+ +    G  VR    E
Sbjct: 186 HLSQGDLRFEPQIALTDFSDGLSCIRTLAQGAPDRLAEGGFLLLEHGFDQGAAVRGVLAE 245

Query: 170 KGFS 173
            GFS
Sbjct: 246 NGFS 249


>sp|P45253|HEMK_HAEIN HEMK PROTEIN HOMOLOG >gi|1075189|pir||H64129 hemK protein (EC
           1.3.3.-) - Haemophilus influenzae (strain Rd KW20)
           >gi|1574403|gb|AAC23208.1| (U32830) hemK protein (hemK)
           [Haemophilus influenzae Rd]
           Length = 292
           
 Score = 70.2 bits (169), Expect = 2e-11
 Identities = 58/186 (31%), Positives = 89/186 (47%), Gaps = 25/186 (13%)

Query: 8   LRIEVEESVYEPAEDTFLLAEALL----EEVREDDI---VLDVGTGSGILAL-LAAKKAK 59
           L + V +    P  DT +L E  L    E++ E+     +LD+GTG+G +AL LA++ A 
Sbjct: 83  LPLNVSKGTLIPRPDTEILVEKALQIALEKLEENPPHFRILDLGTGTGAIALALASELAP 142

Query: 60  F---------VVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPY 110
                     ++G+D+    + LA  NA+ N + NV F+ S  F N+ GKF LI+ NPPY
Sbjct: 143 ICQKRHIPLEIIGVDLMSDVVALAQSNAERNQL-NVEFLQSRWFDNITGKFDLIVSNPPY 201

Query: 111 LPGD-------DVKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNV 163
           +          DV+ E   AL+    G   +   +     YL   G +L+ +    G  V
Sbjct: 202 IDAQDEHLHQGDVRFEPLSALVANDEGYADLRHIIELASSYLNSNGVLLLEHGWQQGEKV 261

Query: 164 REAFEE 169
           R  F+E
Sbjct: 262 RSIFQE 267


>pir||C71566 probable protoporphyrinogen oxidase - Chlamydia trachomatis
           (serotype D, strain UW3/Cx) >gi|3328414|gb|AAC67614.1|
           (AE001277) N6-adenine-specific DNA methylase [Chlamydia
           trachomatis]
           Length = 290
           
 Score = 70.2 bits (169), Expect = 2e-11
 Identities = 58/201 (28%), Positives = 97/201 (47%), Gaps = 18/201 (8%)

Query: 3   IHYNGLRIEVEESVYEPAEDTFLLAEAL---LEEVREDDIVLDVGTGSGILALLAAKKAK 59
           +H+ G+ ++V   V  P ++T +  E +   L+  +E     DV  GSG + L   K   
Sbjct: 73  VHFLGVELQVTPQVLIPRQETEIFVEQIIGYLQMHKEKTTFYDVCCGSGCIGLAVRKHCP 132

Query: 60  FV-VGL-DINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRGKFTLILFNPPYLPGDDVK 117
            V V L DI+ +A+ +A  NA+ N +  V F++ DLF        +++ NPPYL   +  
Sbjct: 133 HVRVTLSDISPEALAIAESNARSNALA-VDFLLGDLFDPFSFPADVLVCNPPYLSYKEFF 191

Query: 118 D--------EIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEE 169
           +        E   AL+GG +G E   +  + +   L+ GG   +   S  G ++++ F  
Sbjct: 192 ESDPEVRCHEPWKALVGGVSGLEFYHRIATHIHKILVSGGVGWLEIGSTQGEDIKQIFHA 251

Query: 170 KGFSTRIVKK----ERFFFEE 186
           KG   R++K     +RFFF E
Sbjct: 252 KGIRGRVLKDYAQLDRFFFLE 272


>pir||G82671 protoporphyrinogen oxidase XF1512 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9106546|gb|AAF84321.1|AE003981_3
           (AE003981) protoporphyrinogen oxidase [Xylella
           fastidiosa]
           Length = 275
           
 Score = 70.2 bits (169), Expect = 2e-11
 Identities = 55/176 (31%), Positives = 84/176 (47%), Gaps = 12/176 (6%)

Query: 8   LRIEVEESVYEPAEDTFLLAEALLEEV--REDDIVLDVGTGSGILALLAA--KKAKFVVG 63
           L + V  +   P  +T  L E  L+ +    +  V D+GTGSG +AL  A  +    V+ 
Sbjct: 76  LDVMVSSATLIPRAETETLVEQALQRLDHASERRVADLGTGSGAIALAIACERPQAQVLA 135

Query: 64  LDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRG-KFTLILFNPPY-------LPGDD 115
            D +  A+D+A RNA  +G+ +VVF   D +  L G +F LI+ NPPY       L   D
Sbjct: 136 TDNSAAALDIAARNASAHGLNHVVFREGDWYEALLGERFDLIVSNPPYIAVTDPHLTQGD 195

Query: 116 VKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKG 171
           ++ E   ALI G  G + +    +    YL PGG +++ +    G  +R      G
Sbjct: 196 LRFEPPSALISGGDGLDALRILTAGAPAYLRPGGWLVMEHGWDQGAAMRTLLHTAG 251


>pir||G72369 hemK protein - Thermotoga maritima (strain MSB8)
           >gi|4980999|gb|AAD35573.1|AE001726_7 (AE001726) hemK
           protein [Thermotoga maritima]
           Length = 282
           
 Score = 69.9 bits (168), Expect = 2e-11
 Identities = 49/145 (33%), Positives = 76/145 (51%), Gaps = 12/145 (8%)

Query: 5   YNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDI--VLDVGTGSGILALLAAKKAKFVV 62
           + GL   VEE V+ P  +T  L E  LE +R+  I  V D+GTGSG + +  AK +  +V
Sbjct: 88  FMGLSFLVEEGVFVPRPETEELVELALELIRKYGIKTVADIGTGSGAIGVSVAKFSDAIV 147

Query: 63  -GLDINEKAIDLAWRNAQLNGIKNVVFV----VSDLFRNLRGKFTLILFNPPYLPGD--- 114
              D++ KA+++A +NA+ +G+ +  FV      + F+       +IL NPPY+      
Sbjct: 148 FATDVSSKAVEIARKNAERHGVSDRFFVRKGEFLEPFKEKFASIEMILSNPPYVKSSAHL 207

Query: 115 --DVKDEIDLALIGGKTGSEVILKF 137
             DV  E   AL GG+ G +   +F
Sbjct: 208 PKDVLFEPPEALFGGEDGLDFYREF 232


>dbj|BAB10283.1| (AB008266) gene_id:MHJ24.13~similar to unknown protein~sp|P74003
           [Arabidopsis thaliana]
           Length = 377
           
 Score = 69.9 bits (168), Expect = 2e-11
 Identities = 52/166 (31%), Positives = 80/166 (47%), Gaps = 20/166 (12%)

Query: 4   HYNGLRIEVEESVYEPAEDTFLLAEALLEEVRED-----DIVLDVGTGSGILALLAAK-- 56
           H+  L + VEE V  P  +T L+ + + E V  D     DI  D+GTGSG +A+  AK  
Sbjct: 163 HWRDLVLCVEEGVLIPRPETELIVDMVEELVTRDEWFKKDIWADLGTGSGAIAIGIAKVL 222

Query: 57  -KAKFVVGLDINEKAIDLAWRNAQLNGIKNVVFVVS----DLFRNLRGKFTLILFNPPYL 111
                V+  D++  AI +A  N Q   ++ ++ V      +  ++L GK   ++ NPPY+
Sbjct: 223 GSRGRVIATDLSPVAIAVAGHNVQRYSLEGMIEVREGSWFEPLKDLEGKLVGLVSNPPYI 282

Query: 112 PGDDV--------KDEIDLALIGGKTGSEVILKFLSDVEDYLLPGG 149
           P DD+        + E  LAL GG  G++ +          L PGG
Sbjct: 283 PSDDIPGLQAEVGRHEPKLALDGGIDGTDSLFHLCHGASRMLQPGG 328


>pir||E81010 hemK protein NMB2065 [imported] - Neisseria meningitidis  (group B
           strain MD58) >gi|7227327|gb|AAF42384.1| (AE002556) hemK
           protein [Neisseria meningitidis MC58]
           Length = 423
           
 Score = 69.5 bits (167), Expect = 3e-11
 Identities = 60/181 (33%), Positives = 84/181 (46%), Gaps = 13/181 (7%)

Query: 5   YNGLRIEVEESVYEPAEDTFLLAEALLEEVREDDIVLDVGTGSGILALLAA--KKAKFVV 62
           + G R  V  SV  P  +T  L EA+L  + E+  V D+GTGSG +A+  A  +   FV 
Sbjct: 220 FYGRRFTVNPSVLIPRPETEHLVEAVLARLPENGRVWDLGTGSGAVAVTVALERPDAFVR 279

Query: 63  GLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRN---LRGKFTLILFNPPYLP-GD---- 114
             DI+  A++ A +NA   G + V F     F       GK+ +I+ NPPY+  GD    
Sbjct: 280 ASDISPPALETARKNAADLGAR-VEFAHGSWFDTDMPSEGKWDIIVSNPPYIENGDKHLL 338

Query: 115 --DVKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYSSLTGLNVREAFEEKGF 172
             D++ E  +AL     G   I        D L  GG +L+ +    G  VR    E GF
Sbjct: 339 QGDLRFEPQIALTDFSDGLSCIRTLAQGAPDRLAEGGFLLLEHGFDQGAAVRGVLAENGF 398

Query: 173 S 173
           S
Sbjct: 399 S 399


>dbj|BAB03843.1| (AP001507) unknown conserved protein [Bacillus halodurans]
           Length = 201
           
 Score = 68.3 bits (164), Expect = 6e-11
 Identities = 50/153 (32%), Positives = 73/153 (47%), Gaps = 29/153 (18%)

Query: 40  VLDVGTGSGILALLAAKKA--KFVVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNL 97
           VLDVG G G + +  A+    + V  +D+NE+AIDLA RNA  N +KNVV   SDLF+ +
Sbjct: 62  VLDVGCGYGPIGISLARDGGERSVHMVDVNERAIDLAKRNATANHVKNVVVYRSDLFQQV 121

Query: 98  RGK-FTLILFNPPYLPGDDVKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILIVYS 156
           + + F  I+ NPP                  + G  V+ +   D  DYLL  G + IV  
Sbjct: 122 QDRQFAAIVTNPPI-----------------RAGKRVVHQLFEDARDYLLSNGELWIVIQ 164

Query: 157 SLTGL-----NVREAFEEKGFSTRIVKKERFFF 184
              G       +   +EE      +V K++ +F
Sbjct: 165 KKQGAPSTLDKLHNLYEE----VEVVTKKKGYF 193


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.321    0.143    0.394 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71656146
Number of Sequences: 2977
Number of extensions: 3009780
Number of successful extensions: 8515
Number of sequences better than 1.0e-10: 31
Number of HSP's better than  0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 8441
Number of HSP's gapped (non-prelim): 32
length of query: 197
length of database: 189,106,746
effective HSP length: 55
effective length of query: 142
effective length of database: 156,189,961
effective search space: 22178974462
effective search space used: 22178974462
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 163 (67.9 bits)