BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0295 (tkt1) DE:Transketolase N-TERMINAL SECTION (220 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||H75160 transketolase n-terminal section PAB0295 - Pyrococcu... 443 e-124 sp|Q58094|TKTN_METJA PUTATIVE TRANSKETOLASE N-TERMINAL SECTION (... 159 3e-38 pir||B72644 probable transketolase APE0586 - Aeropyrum pernix (s... 157 8e-38 gb|AAK40638.1| Transketolase, N-terminal section (tkt-1) [Sulfol... 140 1e-32 emb|CAC11757.1| (AL445064) probable transketolase [Thermoplasma ... 135 4e-31 pir||T20473 hypothetical protein F01G10.1 - Caenorhabditis elega... 118 7e-26 gb|AAF76194.1| (AF270484) transketolase [Xenopus laevis] 115 4e-25 sp|P55574|Y4MO_RHISN HYPOTHETICAL TRANSKETOLASE FAMILY PROTEIN Y... 115 4e-25 pir||T34727 transketolase - Streptomyces coelicolor >gi|3861429|... 113 1e-24 gb|AAF49267.1| (AE003521) CG5103 gene product [Drosophila melano... 112 4e-24 dbj|BAA74730.1| (AB016786) transketolase [Ascidia sydneiensis sa... 111 9e-24 gb|AAF54265.1| (AE003680) CG8036 gene product [Drosophila melano... 109 4e-23 pir||B72215 hypothetical protein TM1762 - Thermotoga maritima (s... 104 9e-22 gi|4507521 transketolase (Wernicke-Korsakoff syndrome) [Homo sap... 102 5e-21 gb|AAA61222.1| (L12711) transketolase [Homo sapiens] 102 5e-21 pir||A45050 transketolase (EC 2.2.1.1) - human >gi|37267|emb|CAA... 102 5e-21 gb|AAA18026.1| (U09256) transketolase [Rattus norvegicus] 98 9e-20 sp|P50137|TKT_RAT TRANSKETOLASE (TK) 98 9e-20 gi|6678359 transketolase [Mus musculus] >gi|730956|sp|P40142|TKT... 98 1e-19 gb|AAG28459.1|AF195533_1 (AF195533) transketolase [Mus musculus] 98 1e-19 gi|7110727 transketolase-like 1; Transketolase-2 [Homo sapiens] ... 92 4e-18 emb|CAA60226.1| (X86506) tkt [Clostridium perfringens] 89 4e-17 gi|6325331 Transketolase 1; Tkl1p [Saccharomyces cerevisiae] >gi... 89 6e-17 pdb|1TKB|A Chain A, Transketolase (E.C.2.2.1.1) Complexed With 1... 89 6e-17 pdb|1AY0|A Chain A, Identification Of Catalytically Important Re... 89 6e-17 sp|Q12630|TKT1_KLULA TRANSKETOLASE (TK) >gi|1488336|gb|AAB05935.... 85 7e-16 emb|CAB58135.1| (AJ249787) putative transketolase precursor [Cya... 85 7e-16 gi|6319593 transketolase, homologous to tkl1; Tkl2p [Saccharomyc... 85 9e-16 gb|AAC01739.1| (AF040571) transketolase [Amycolatopsis mediterra... 84 1e-15 pir||H70451 transketolase - Aquifex aeolicus >gi|2984067|gb|AAC0... 83 3e-15 sp|P34736|TKT_PICST TRANSKETOLASE (TK) >gi|480852|pir||S37439 tr... 82 6e-15 pir||T09541 transketolase (EC 2.2.1.1) TKT1 precursor, chloropla... 82 7e-15 sp|O06811|TKT_MYCTU TRANSKETOLASE (TK) >gi|7433614|pir||D70917 p... 81 1e-14 pir||S77463 transketolase (EC 2.2.1.1) - Synechocystis sp. (stra... 80 2e-14 sp|Q43848|TKTC_SOLTU TRANSKETOLASE, CHLOROPLAST PRECURSOR (TK) >... 80 2e-14 pir||S58083 transketolase (EC 2.2.1.1) precursor - potato (fragm... 80 2e-14 pir||T47886 transketolase-like protein - Arabidopsis thaliana >g... 80 2e-14 sp|P43757|TKT_HAEIN TRANSKETOLASE (TK) >gi|1075385|pir||G64108 t... 80 3e-14 emb|CAC18218.1| (AL451017) probable TRANSKETOLASE [Neurospora cr... 79 4e-14 sp|Q42677|TKT7_CRAPL TRANSKETOLASE 7 (TK) >gi|1084441|pir||S5430... 78 6e-14 sp|P46708|TKT_MYCLE TRANSKETOLASE (TK) >gi|2145978|pir||S72772 t... 78 1e-13 pir||T40162 transketolase - fission yeast (Schizosaccharomyces p... 77 1e-13 pir||T18231 transketolase I - yeast (Candida albicans) >gi|38597... 77 1e-13 gb|AAA35168.1| (M63302) transkelotase [Saccharomyces cerevisiae] 77 2e-13 sp|Q42675|TKTA_CRAPL TRANSKETOLASE 10 (TK) >gi|1084439|pir||S542... 77 2e-13 pir||H81737 transketolase TC0131 [imported] - Chlamydia muridaru... 77 2e-13 pir||T09015 transketolase (EC 2.2.1.1) precursor, chloroplast - ... 76 2e-13 dbj|BAA74963.1| (AB023377) transketolase [Corynebacterium glutam... 76 2e-13 pir||T36007 probable transketolase - Streptomyces coelicolor >gi... 76 2e-13 dbj|BAB06071.1| (AP001515) transketolase [Bacillus halodurans] 76 2e-13 pir||JC7146 transketolase (EC 2.2.1.1) - Corynebacterium glutamicum 76 2e-13 pir||C71475 probable transketolase - Chlamydia trachomatis (sero... 75 6e-13 gb|AAB82634.1| (AC002387) putative transketolase precursor [Arab... 75 7e-13 sp|P33570|TKT2_ECOLI TRANSKETOLASE 2 (TK 2) >gi|477312|pir||A486... 74 1e-12 sp|P06834|DAS_PICAN DIHYDROXY-ACETONE SYNTHASE (DHAS) (FORMALDEH... 74 2e-12 pir||H64655 transketolase A - Helicobacter pylori (strain 26695)... 73 2e-12 sp|P46374|FAS2_RHOFA FERREDOXIN FAS2 >gi|1076044|pir||B55578 fer... 73 3e-12 emb|CAB82464.1| (AJ132348) transketolase, putative [Staphylococc... 73 3e-12 sp|P75611|TKT_MYCPN TRANSKETOLASE (TK) >gi|2146671|pir||S73399 t... 73 4e-12 gb|AAA96741.1| (U29134) transketolase [Xanthobacter flavus] 72 6e-12 sp|P45694|TKT_BACSU TRANSKETOLASE >gi|7433610|pir||G69723 transk... 71 1e-11 pir||T35162 transketolase - Streptomyces coelicolor >gi|3334794|... 71 1e-11 pir||D71944 transketolase - Helicobacter pylori (strain J99) >gi... 71 1e-11 gb|AAC83349.1| (AF086822) dihydroxyacetone synthase [Candida boi... 70 2e-11 pir||C81261 transketolase (EC 2.2.1.1) Cj1645 [imported] - Campy... 69 4e-11 pir||B81082 transketolase NMB1457 [imported] - Neisseria meningi... 69 5e-11 pir||A81862 transketolase (EC 2.2.1.1) NMA1669 [imported] - Neis... 69 5e-11 sp|P47312|TKT_MYCGE TRANSKETOLASE (TK) >gi|1361873|pir||C64207 t... 68 9e-11 pir||H75295 transketolase - Deinococcus radiodurans (strain R1) ... 68 9e-11 >pir||H75160 transketolase n-terminal section PAB0295 - Pyrococcus abyssi (strain Orsay) >gi|5457877|emb|CAB49367.1| (AJ248284) Transketolase N-TERMINAL SECTION [Pyrococcus abyssi] Length = 220 Score = 443 bits (1127), Expect = e-124 Identities = 220/220 (100%), Positives = 220/220 (100%) Query: 1 MMGLNEVLLTKLKDMLRPVNGFHMHSSLTCLSILQAVLEVKRSDDVVILSKGHSAPAFYV 60 MMGLNEVLLTKLKDMLRPVNGFHMHSSLTCLSILQAVLEVKRSDDVVILSKGHSAPAFYV Sbjct: 1 MMGLNEVLLTKLKDMLRPVNGFHMHSSLTCLSILQAVLEVKRSDDVVILSKGHSAPAFYV 60 Query: 61 MLWKLGLLRDEDLEKFADIDGLPSHVTRGLPFIEVSSGSLGQGLSVANGIAMAKRIDGKS 120 MLWKLGLLRDEDLEKFADIDGLPSHVTRGLPFIEVSSGSLGQGLSVANGIAMAKRIDGKS Sbjct: 61 MLWKLGLLRDEDLEKFADIDGLPSHVTRGLPFIEVSSGSLGQGLSVANGIAMAKRIDGKS 120 Query: 121 GRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKW 180 GRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKW Sbjct: 121 GRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKW 180 Query: 181 KAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAKWSY 220 KAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAKWSY Sbjct: 181 KAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAKWSY 220 >sp|Q58094|TKTN_METJA PUTATIVE TRANSKETOLASE N-TERMINAL SECTION (TK) >gi|2129317|pir||A64385 transketolase (EC 2.2.1.1) - Methanococcus jannaschii >gi|1591396|gb|AAB98676.1| (U67515) transketolase' [Methanococcus jannaschii] Length = 274 Score = 159 bits (397), Expect = 3e-38 Identities = 83/181 (45%), Positives = 121/181 (65%), Gaps = 7/181 (3%) Query: 41 KRSDDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGS 99 K+ D +LSKGH+APA Y +L +LG++ +E+L K ++G L H + P +E+ +GS Sbjct: 60 KKDRDRFVLSKGHAAPALYAVLSELGIIEEEELWKLRRLEGKLQGHPSMDTPGVEICTGS 119 Query: 100 LGQGLSVANGIAMAKRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRN 159 LGQG S A G+A+ R+D + V+V+LGDGE EG +WEAAM A+HY LDN+IA +DRN Sbjct: 120 LGQGFSAAVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEAAMAAAHYKLDNLIAFIDRN 179 Query: 160 YGQLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVK----GKPKVII 215 Q+ G TE +MS + K++AFGW V E+ + + +E+IN ++ K GKPK+II Sbjct: 180 KLQIDGCTEDVMSLGDIKAKFEAFGWDVFEI--DGHNFEEIINTVEKAKSMKNGKPKMII 237 Query: 216 A 216 A Sbjct: 238 A 238 >pir||B72644 probable transketolase APE0586 - Aeropyrum pernix (strain K1) >gi|5104239|dbj|BAA79554.1| (AP000060) 367aa long hypothetical transketolase [Aeropyrum pernix] Length = 367 Score = 157 bits (394), Expect = 8e-38 Identities = 91/207 (43%), Positives = 124/207 (58%), Gaps = 12/207 (5%) Query: 21 GFHMHSSLTCLSILQAVL-------EVKRSDDVVILSKGHSAPAFYVMLWKLGLLRDEDL 73 G+H+HSS T L IL + V+ D VILSKGH++ FY +L ++GLL + Sbjct: 159 GWHLHSSTTALPILAVLYAYWLPRGRVEGVDRRVILSKGHASLGFYALLEEMGLLERGSV 218 Query: 74 EKFADIDGLP--SHVTRG-LPFIEVSSGSLGQGLSVANGIAMAKRIDGKSGRVFVILGDG 130 E+ G P +H G P VS+GSLGQ LSV+NG+ + R+ G+ V V+LGDG Sbjct: 219 ERLFARPGSPLQAHPEAGRTPLTLVSNGSLGQALSVSNGLVIGSRLKGRRVEVAVVLGDG 278 Query: 131 ELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREV 190 ELDEGQ+WEAA TA+ L V+AIVDRN Q +G TE I KEPL D+W++FGW+ V Sbjct: 279 ELDEGQVWEAAATAAAMRLWEVVAIVDRNRVQHTGETEAIKPKEPLEDRWRSFGWEAVTV 338 Query: 191 KNEVESLKEVINELDGVKGKPKVIIAK 217 + VE + ++ G +P II + Sbjct: 339 EGRVEEIARALDSRAG--DRPTAIIVE 363 >gb|AAK40638.1| Transketolase, N-terminal section (tkt-1) [Sulfolobus solfataricus] Length = 281 Score = 140 bits (349), Expect = 1e-32 Identities = 85/204 (41%), Positives = 123/204 (59%), Gaps = 10/204 (4%) Query: 23 HMHSSLTCLSILQAVL-EVKRSD------DVVILSKGHSAPAFYVMLWKLGLLRDEDLEK 75 H+ SSL+ + IL ++ + R+D D +ILSKGH+APA Y +L + G +++E+L + Sbjct: 49 HVGSSLSSIEILTTLIFKHIRTDSSLVNKDWLILSKGHAAPALYAVLAEKGYIKEEELWR 108 Query: 76 FADIDGL-PSHVTRGLPFIEVSSGSLGQGLSVANGIAMAKRIDGKSGRVFVILGDGELDE 134 DI GL H +P +++S+GSLGQGLS G+A ++ +GRV+VI+GDGE DE Sbjct: 109 IQDITGLLQGHPETFIPGVDMSTGSLGQGLSFGIGVATGIKMANGTGRVYVIMGDGEQDE 168 Query: 135 GQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK-NE 193 G+IWEA A LDN+IA ++ N QL G+T+ I K L W+A GWKV ++ Sbjct: 169 GEIWEAMTHAVVRNLDNLIAFIEMNNFQLDGSTDEIKPKNFLPKVWEAVGWKVLNCDGHD 228 Query: 194 VESLKEVINELDGVKGKPKVIIAK 217 S+ +NE KP VI AK Sbjct: 229 FISITNAVNEAYKA-SKPVVIFAK 251 >emb|CAC11757.1| (AL445064) probable transketolase [Thermoplasma acidophilum] Length = 273 Score = 135 bits (337), Expect = 4e-31 Identities = 88/227 (38%), Positives = 125/227 (54%), Gaps = 14/227 (6%) Query: 4 LNEVLLTKLKDMLRPV---NGFHMHSSLTCLSILQAV------LEVKRSDDV----VILS 50 L+E+ L ++++R V H SL+ IL + ++ K +D +ILS Sbjct: 8 LSEIALRIRREIVRMVYNAQSGHPGGSLSVADILTVLYFKEMNIDPKNPNDPKRDRLILS 67 Query: 51 KGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQGLSVANG 109 KGH++PA Y L G DL F ID L HV+R +P +EVS+GSLGQGL V G Sbjct: 68 KGHASPALYATLALRGFFPVSDLAGFRKIDSHLEGHVSREIPGVEVSTGSLGQGLGVGVG 127 Query: 110 IAMAKRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTER 169 +A+A R++G + V+VILGDGE++EG +WE+ M Y L+N++AI+DRN QL G T Sbjct: 128 MALASRLNGFNYHVYVILGDGEMEEGNVWESLMAGYKYKLNNLVAILDRNGIQLDGYTRD 187 Query: 170 IMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIA 216 IM + ++FGW V E+ S E E +P IIA Sbjct: 188 IMPLHDIHAMVESFGWNVIEIDGHSFSEIEDAIEKSKRSERPTFIIA 234 >pir||T20473 hypothetical protein F01G10.1 - Caenorhabditis elegans >gi|3875549|emb|CAB02889.1| (Z81055) predicted using Genefinder~Similarity to Human transketolase (SW:TKT_HUMAN), contains similarity to Pfam domain: PF00456 (Transketolase), Score=557.7, E-value=2.4e-164, N=2~cDNA EST cm01f8 comes from this gene~cDNA EST EMBL:M75846 comes from t> Length = 618 Score = 118 bits (292), Expect = 7e-26 Identities = 78/178 (43%), Positives = 97/178 (53%), Gaps = 3/178 (1%) Query: 43 SDDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLG 101 S D +LSKGH+ P Y + GLL E + ID + H T L FI+V++GSLG Sbjct: 63 SADRFVLSKGHACPILYAAWEEAGLLSHEQVLSLRKIDSDIEGHPTPRLNFIDVATGSLG 122 Query: 102 QGLSVANGIA-MAKRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNY 160 QGL VA G+A + K ID S RVF +LGDGE EG +WEAA AS Y LDN++AIVD N Sbjct: 123 QGLGVATGMAYVGKYIDKASYRVFCLLGDGESAEGSVWEAAAFASIYKLDNLVAIVDVNR 182 Query: 161 GQLSGNTERIMSKEPLADKWKAFGWKVREVK-NEVESLKEVINELDGVKGKPKVIIAK 217 S T E ++ AFG+ V + V+ L KGKP IIAK Sbjct: 183 LGQSQATSLGHDVETYKARFAAFGFNAIIVNGHNVDELLAAYETARSTKGKPTAIIAK 240 >gb|AAF76194.1| (AF270484) transketolase [Xenopus laevis] Length = 625 Score = 115 bits (286), Expect = 4e-25 Identities = 72/178 (40%), Positives = 96/178 (53%), Gaps = 3/178 (1%) Query: 43 SDDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADID-GLPSHVTRGLPFIEVSSGSLG 101 ++D +LSKGH+AP Y + G ++ DL ID L H T LPF++V++GSLG Sbjct: 67 NNDRFVLSKGHAAPILYAAWAEAGFIKQSDLLNLRKIDCDLEGHPTPKLPFVDVATGSLG 126 Query: 102 QGLSVANGIAMA-KRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNY 160 QGL + G+A K D S RV+ +LGDGE EG +WEA ASHY LDN++AI D N Sbjct: 127 QGLGASCGMAYTGKYFDKASYRVYCLLGDGESSEGAVWEAMAFASHYHLDNLVAIFDVNR 186 Query: 161 GQLSGNTERIMSKEPLADKWKAFGWKVREVK-NEVESLKEVINELDGVKGKPKVIIAK 217 S + + +AFGW V ++V L + VK KP IIAK Sbjct: 187 LGQSEAAPLQHQTDIYMKRCEAFGWNTYVVDGHDVAELCHAFWQAAHVKDKPTAIIAK 244 >sp|P55574|Y4MO_RHISN HYPOTHETICAL TRANSKETOLASE FAMILY PROTEIN Y4MO >gi|2182532|gb|AAB91778.1| (AE000085) Y4mO [Rhizobium sp. NGR234] Length = 279 Score = 115 bits (286), Expect = 4e-25 Identities = 68/175 (38%), Positives = 105/175 (59%), Gaps = 4/175 (2%) Query: 45 DVVILSKGHSAPAFYVMLWKLGLLRDEDLEKF-ADIDGLP-SHVTRGLPFIEVSSGSLGQ 102 D +LS GH A A Y L + ++ +++LE + AD LP S + P +E++ GSLG Sbjct: 64 DRFLLSIGHYAIALYAALIEAKIIPEDELETYGADDSRLPMSGMAAYTPGMEITGGSLGH 123 Query: 103 GLSVANGIAMAKRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQ 162 GL +A G+++A + G V+ + DGELDEG WEAAM+A Y LDN+I IVD N Q Sbjct: 124 GLGIAVGMSLALKRKGSRSFVYNLFSDGELDEGSTWEAAMSAGSYKLDNLIGIVDVNQMQ 183 Query: 163 LSGNTERIMSKEPLADKWKAFGWKVREVK-NEVESLKEVI-NELDGVKGKPKVII 215 G + +++ EPL K++AFGW V+ + N++++L + N +P++II Sbjct: 184 ADGPSLGVLNFEPLGPKFEAFGWYVQRIDGNDIDALVDAFDNARQHRHPQPRIII 238 >pir||T34727 transketolase - Streptomyces coelicolor >gi|3861429|emb|CAA22034.1| (AL033505) transketolase [Streptomyces coelicolor A3(2)] Length = 615 Score = 113 bits (281), Expect = 1e-24 Identities = 71/180 (39%), Positives = 103/180 (56%), Gaps = 8/180 (4%) Query: 44 DDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKF----ADIDGLPSHVTRGLPFIEVSSGS 99 +D +LSKGH++P Y G + DE+L F + ++G P+ + LP++E ++GS Sbjct: 59 NDRFVLSKGHASPLLYSAFKAAGAIDDEELLTFRKQGSRLEGHPT--PQRLPWVETATGS 116 Query: 100 LGQGLSVANGIAMA-KRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDR 158 LGQGL V GIA++ KR+D RV+V+ GD EL EG IWEAA A H LDN+ IVD Sbjct: 117 LGQGLPVGVGIALSGKRLDHTDYRVWVLCGDSELAEGSIWEAAEHAGHEHLDNLTVIVDV 176 Query: 159 NYGQLSGNTERIMSKEPLADKWKAFGWKVREVK-NEVESLKEVINELDGVKGKPKVIIAK 217 N G T + A +++AF W EV ++V+++ E KG+P IIA+ Sbjct: 177 NRLGQRGPTRHGHDLDAYARRFRAFEWHTIEVDGHDVDAVDRAYGEALSTKGQPTAIIAR 236 >gb|AAF49267.1| (AE003521) CG5103 gene product [Drosophila melanogaster] Length = 623 Score = 112 bits (277), Expect = 4e-24 Identities = 76/222 (34%), Positives = 115/222 (51%), Gaps = 12/222 (5%) Query: 4 LNEVLLTKLKDMLRPVNGFHMHSSLTCLSILQAVLEVKR----SDDVVILSKGHSAPAFY 59 ++ + T+ P + + +T L Q L +K S D ++LSKGH+AP Y Sbjct: 23 IHSITSTQAAKSGHPTSCASLAEIMTVLFFQQMRLNLKHPRDPSSDRLVLSKGHAAPILY 82 Query: 60 VMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQGLSVANGIA-MAKRID 117 + + GL E+L +D L H T L F++VS+GSLGQG+SVA G+A + K +D Sbjct: 83 AVWAEAGLFPVEELRNLRKVDSDLEGHPTPRLSFVDVSTGSLGQGISVAAGMAYVGKHLD 142 Query: 118 GKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSG-NTERIMSKEPL 176 R +VI+GDGE EG +WE+ A HY LDN+ I D N S TE + +E L Sbjct: 143 KADYRTYVIVGDGEATEGAVWESLHFAGHYCLDNLCVIFDMNKIFCSDIGTEMEVYRERL 202 Query: 177 ADKWKAFGWKVREVK-NEVESLKEVINELDGVKGKPKVIIAK 217 AFG+ + ++++ L + KGKP ++A+ Sbjct: 203 ----DAFGFNALVLNGHDIDELAKAFINAASTKGKPTALLAR 240 >dbj|BAA74730.1| (AB016786) transketolase [Ascidia sydneiensis samea] Length = 624 Score = 111 bits (274), Expect = 9e-24 Identities = 76/211 (36%), Positives = 109/211 (51%), Gaps = 13/211 (6%) Query: 20 NGFHMHSSLTCLSILQAV--------LEVKR--SDDVVILSKGHSAPAFYVMLWKLGLLR 69 N H SS +C IL + ++V R S D ++SKGH+ PA Y + G + Sbjct: 34 NSGHPTSSSSCAEILSVLFFRIMKYKVDVPRDISSDRFVMSKGHACPALYSAWVETGHMT 93 Query: 70 DEDLEKFADIDGL-PSHVTRGLPFIEVSSGSLGQGLSVANGIA-MAKRIDGKSGRVFVIL 127 E L + + H T + FI+V++GSLGQGL +A G+A + K ID + RV+ +L Sbjct: 94 KEQLMTLRENGSVYEGHPTPKIDFIDVATGSLGQGLGMAAGMAYVGKYIDKSNYRVYCLL 153 Query: 128 GDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKV 187 GDGE+ EG +WEA ASHY LDN++AI+D S T E + +AFGW Sbjct: 154 GDGEVAEGAVWEAMAFASHYKLDNLVAIIDVTRLGQSEETALGHHTEIYKKRAEAFGWNS 213 Query: 188 REVKNE-VESLKEVINELDGVKGKPKVIIAK 217 EV V L + + + K P ++AK Sbjct: 214 IEVDGHCVSELSKSFHLAESCKDLPTCLVAK 244 >gb|AAF54265.1| (AE003680) CG8036 gene product [Drosophila melanogaster] Length = 626 Score = 109 bits (269), Expect = 4e-23 Identities = 72/178 (40%), Positives = 93/178 (51%), Gaps = 3/178 (1%) Query: 43 SDDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLG 101 S D ILSKGH+AP Y + GL DL ID L H T L FI+V +GSLG Sbjct: 66 SSDRFILSKGHAAPILYAAWAEAGLFPIADLNNLRKIDSDLEGHPTPRLNFIDVGTGSLG 125 Query: 102 QGLSVANGIA-MAKRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNY 160 QG++V G+A + K D R +V++GDGE EG IWE+ A HY LDN+ I D N Sbjct: 126 QGVAVGAGMAYVGKNFDKADYRTYVVVGDGESAEGSIWESLHFAGHYKLDNLCVIFDVNR 185 Query: 161 GQLSGNTERIMSKEPLADKWKAFGWKVREVK-NEVESLKEVINELDGVKGKPKVIIAK 217 S T + D+ +AFG+ V ++VE L + + K KP IIAK Sbjct: 186 LGQSEATSLQHKLDVYRDRLEAFGFNAVVVDGHDVEELSKAFHCAAITKNKPTAIIAK 243 >pir||B72215 hypothetical protein TM1762 - Thermotoga maritima (strain MSB8) >gi|4982340|gb|AAD36826.1|AE001814_8 (AE001814) transketolase, putative [Thermotoga maritima] Length = 635 Score = 104 bits (257), Expect = 9e-22 Identities = 63/176 (35%), Positives = 97/176 (54%), Gaps = 4/176 (2%) Query: 45 DVVILSKGHSAPAFYVMLWKLGLLR-DEDLEKFADIDGL-PSHVTRGLPFIEVSSGSLGQ 102 D +++S GH++P Y + +LG + DE L F + HVTRG+ I+ ++G+LGQ Sbjct: 68 DRIVISHGHTSPGVYAAMARLGFVDLDEVLAGFRHPASVFEGHVTRGVGIIDWTTGNLGQ 127 Query: 103 GLSVANGIAMAKRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQ 162 GLS G A+A R GK VFV++ D E +GQ+ EA A YG+ N+ I+D N Q Sbjct: 128 GLSAGLGFALASRFTGKDYHVFVLMSDAEQAKGQVAEARRVAKKYGVTNLTVIIDYNDAQ 187 Query: 163 LSGNTERIMSKEPLADKWKAFGWKVREVK-NEVESLKEVINELDGVKGKPKVIIAK 217 +SG +M + + + A GW+V E+ ++ E + + E + P IIAK Sbjct: 188 ISGRARDVMPVN-IKENYLADGWRVIEIDGHDYEQIYLALKEAVEDELNPVAIIAK 242 >gi|4507521 transketolase (Wernicke-Korsakoff syndrome) [Homo sapiens] >gi|11434224|ref|XP_003107.1| transketolase (Wernicke-Korsakoff syndrome) [Homo sapiens] >gi|1729976|sp|P29401|TKT_HUMAN TRANSKETOLASE (TK) >gi|1297297|gb|AAA98961.1| (U55017) transketolase [Homo sapiens] Length = 623 Score = 102 bits (251), Expect = 5e-21 Identities = 67/176 (38%), Positives = 92/176 (52%), Gaps = 4/176 (2%) Query: 44 DDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 +D +LSKGH+AP Y + + G L + +L I L H F +V++GSLGQ Sbjct: 68 NDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQ 127 Query: 103 GLSVANGIAMA-KRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYG 161 GL A G+A K D S RV+ +LGDGEL EG +WEA AS Y LDN++AI+D N Sbjct: 128 GLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRL 187 Query: 162 QLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAK 217 S + + +AFGW V + S++E+ K +P IIAK Sbjct: 188 GQSDPAPLQHQMDIYQKRCEAFGWHAIIV--DGHSVEELCKAFGQAKHQPTAIIAK 241 >gb|AAA61222.1| (L12711) transketolase [Homo sapiens] Length = 623 Score = 102 bits (251), Expect = 5e-21 Identities = 67/176 (38%), Positives = 92/176 (52%), Gaps = 4/176 (2%) Query: 44 DDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 +D +LSKGH+AP Y + + G L + +L I L H F +V++GSLGQ Sbjct: 68 NDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQ 127 Query: 103 GLSVANGIAMA-KRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYG 161 GL A G+A K D S RV+ +LGDGEL EG +WEA AS Y LDN++AI+D N Sbjct: 128 GLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRL 187 Query: 162 QLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAK 217 S + + +AFGW V + S++E+ K +P IIAK Sbjct: 188 GQSDPAPLQHQMDIYQKRCEAFGWHAIIV--DGHSVEELCKAFGQAKHQPTAIIAK 241 >pir||A45050 transketolase (EC 2.2.1.1) - human >gi|37267|emb|CAA47919.1| (X67688) transketolase [Homo sapiens] Length = 623 Score = 102 bits (251), Expect = 5e-21 Identities = 67/176 (38%), Positives = 92/176 (52%), Gaps = 4/176 (2%) Query: 44 DDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 +D +LSKGH+AP Y + + G L + +L I L H F +V++GSLGQ Sbjct: 68 NDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQ 127 Query: 103 GLSVANGIAMA-KRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYG 161 GL A G+A K D S RV+ +LGDGEL EG +WEA AS Y LDN++AI+D N Sbjct: 128 GLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRL 187 Query: 162 QLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAK 217 S + + +AFGW V + S++E+ K +P IIAK Sbjct: 188 GQSDPAPLQHQMDIYQKRCEAFGWHAIIV--DGHSVEELCKAFGQAKHQPTAIIAK 241 >gb|AAA18026.1| (U09256) transketolase [Rattus norvegicus] Length = 655 Score = 97.9 bits (240), Expect = 9e-20 Identities = 65/176 (36%), Positives = 90/176 (50%), Gaps = 4/176 (2%) Query: 44 DDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 +D +LSKGH+AP Y + + G L + +L I L H F +V++GSLGQ Sbjct: 100 NDRFVLSKGHAAPILYAVWAEAGFLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQ 159 Query: 103 GLSVANGIAMA-KRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYG 161 GL A G+A K D S RV+ +LGDGE+ EG +WEA A Y LDN++AI D N Sbjct: 160 GLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRL 219 Query: 162 QLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAK 217 S + + +AFGW V + S++E+ K +P IIAK Sbjct: 220 GQSDPAPLQHQVDVYQKRCEAFGWHAIIV--DGHSVEELCKAFGQAKHQPTAIIAK 273 >sp|P50137|TKT_RAT TRANSKETOLASE (TK) Length = 623 Score = 97.9 bits (240), Expect = 9e-20 Identities = 65/176 (36%), Positives = 90/176 (50%), Gaps = 4/176 (2%) Query: 44 DDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 +D +LSKGH+AP Y + + G L + +L I L H F +V++GSLGQ Sbjct: 68 NDRFVLSKGHAAPILYAVWAEAGFLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQ 127 Query: 103 GLSVANGIAMA-KRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYG 161 GL A G+A K D S RV+ +LGDGE+ EG +WEA A Y LDN++AI D N Sbjct: 128 GLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRL 187 Query: 162 QLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAK 217 S + + +AFGW V + S++E+ K +P IIAK Sbjct: 188 GQSDPAPLQHQVDVYQKRCEAFGWHAIIV--DGHSVEELCKAFGQAKHQPTAIIAK 241 >gi|6678359 transketolase [Mus musculus] >gi|730956|sp|P40142|TKT_MOUSE TRANSKETOLASE (TK) (P68) >gi|452486|gb|AAC52443.1| (U05809) transketolase [Mus musculus] Length = 623 Score = 97.5 bits (239), Expect = 1e-19 Identities = 65/176 (36%), Positives = 90/176 (50%), Gaps = 4/176 (2%) Query: 44 DDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 +D +LSKGH+AP Y + + G L + +L I L H F +V++GSLGQ Sbjct: 68 NDRFVLSKGHAAPILYAVWAEAGFLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQ 127 Query: 103 GLSVANGIAMA-KRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYG 161 GL A G+A K D S RV+ +LGDGE+ EG +WEA A Y LDN++AI D N Sbjct: 128 GLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRL 187 Query: 162 QLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAK 217 S + + +AFGW V + S++E+ K +P IIAK Sbjct: 188 GQSDPAPLQHQVDIYQKRCEAFGWHTIIV--DGHSVEELCKAFGQAKHQPTAIIAK 241 >gb|AAG28459.1|AF195533_1 (AF195533) transketolase [Mus musculus] Length = 559 Score = 97.5 bits (239), Expect = 1e-19 Identities = 65/176 (36%), Positives = 90/176 (50%), Gaps = 4/176 (2%) Query: 44 DDVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 +D +LSKGH+AP Y + + G L + +L I L H F +V++GSLGQ Sbjct: 4 NDRFVLSKGHAAPILYAVWAEAGFLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQ 63 Query: 103 GLSVANGIAMA-KRIDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYG 161 GL A G+A K D S RV+ +LGDGE+ EG +WEA A Y LDN++AI D N Sbjct: 64 GLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRL 123 Query: 162 QLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVKGKPKVIIAK 217 S + + +AFGW V + S++E+ K +P IIAK Sbjct: 124 GQSDPAPLQHQVDIYQKRCEAFGWHTIIV--DGHSVEELCKAFGQAKHQPTAIIAK 177 >gi|7110727 transketolase-like 1; Transketolase-2 [Homo sapiens] >gi|11419900|ref|XP_010159.1| transketolase-like 1 [Homo sapiens] >gi|1729975|sp|P51854|TKT2_HUMAN TRANSKETOLASE 2 (TK 2) (TRANSKETOLASE RELATED PROTEIN) >gi|1232175|emb|CAA62925.1| (X91817) transketolase [Homo sapiens] >gi|1588307|prf||2208324A transketolase [Homo sapiens] Length = 557 Score = 92.4 bits (226), Expect = 4e-18 Identities = 60/162 (37%), Positives = 86/162 (53%), Gaps = 10/162 (6%) Query: 58 FYVMLWKLGLLRDEDLEKFADIDGLPSHVTRGLPFIEVSSGSLGQGLSVANGIAMA-KRI 116 FY+M +K + D ++F + + L F++V++G LGQGL VA G+A K Sbjct: 6 FYIMRYKQSDPENPDNDRFV--------LAKRLSFVDVATGWLGQGLGVACGMAYTGKYF 57 Query: 117 DGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPL 176 D S RVF ++ DGE EG +WEA AS+Y LDN++AI D N SG Sbjct: 58 DRASYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIY 117 Query: 177 ADKWKAFGWKVREVK-NEVESLKEVINELDGVKGKPKVIIAK 217 + +AFGW V +VE+L +V + VK KP ++AK Sbjct: 118 QRRCEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAK 159 >emb|CAA60226.1| (X86506) tkt [Clostridium perfringens] Length = 137 Score = 88.9 bits (217), Expect = 4e-17 Identities = 44/98 (44%), Positives = 63/98 (63%), Gaps = 1/98 (1%) Query: 119 KSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLAD 178 K RVF ILGDGEL+EGQ+WEAAM+A+HY LD++ A VD N Q+ G+ + +MS P+ Sbjct: 1 KDYRVFTILGDGELEEGQVWEAAMSAAHYRLDHLTAFVDFNGLQIDGDIKEVMSPCPIDK 60 Query: 179 KWKAFGWKVREVK-NEVESLKEVINELDGVKGKPKVII 215 K++AFGW V + ++ + I + KG P I+ Sbjct: 61 KFEAFGWNVIVINGHDYGEIINAIQKAKSTKGAPTCIV 98 >gi|6325331 Transketolase 1; Tkl1p [Saccharomyces cerevisiae] >gi|1351256|sp|P23254|TKT1_YEAST TRANSKETOLASE 1 (TK 1) >gi|1360730|pir||A49510 transketolase (EC 2.2.1.1) TKL1 - yeast (Saccharomyces cerevisiae) >gi|7427899|pir||XJBYTK transketolase (EC 2.2.1.1) TKL1 - yeast (Saccharomyces cerevisiae) >gi|515259|pdb|1TRK|A Chain A, Transketolase (E.C.2.2.1.1) >gi|515260|pdb|1TRK|B Chain B, Transketolase (E.C.2.2.1.1) >gi|1942293|pdb|1NGS|A Chain A, Complex Of Transketolase With Thiamin Diphosphate, Ca2+ And Acceptor Substrate Erythrose-4-Phosphate >gi|1942294|pdb|1NGS|B Chain B, Complex Of Transketolase With Thiamin Diphosphate, Ca2+ And Acceptor Substrate Erythrose-4-Phosphate >gi|404201|emb|CAA51693.1| (X73224) transketolase [Saccharomyces cerevisiae] >gi|805054|emb|CAA89191.1| (Z49219) Tkl1p [Saccharomyces cerevisiae] >gi|1230682|gb|AAB68125.1| (U51033) Transketolase 1 (Swiss Prot. accession number P23254); This gene is also found in EMBL accession number Z49219 [Saccharomyces cerevisiae] >gi|1314142|emb|CAA94982.1| (Z71255) Tkl1p [Saccharomyces cerevisiae] Length = 680 Score = 88.5 bits (216), Expect = 6e-17 Identities = 66/185 (35%), Positives = 94/185 (50%), Gaps = 16/185 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 D +LS GH+ Y ML G L EDL++F + P H LP +EV++G LGQ Sbjct: 61 DRFVLSNGHAVALLYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQ 120 Query: 103 GLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNV 152 G+S A G+AMA+ +V LGDG L EG EA+ A H L N+ Sbjct: 121 GISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNL 180 Query: 153 IAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGVKG 209 IAI D N + G T I E +A +++A+GW+V V+N ++ + + I + K Sbjct: 181 IAIYDDNKITIDGATS-ISFDEDVAKRYEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKD 239 Query: 210 KPKVI 214 KP +I Sbjct: 240 KPTLI 244 >pdb|1TKB|A Chain A, Transketolase (E.C.2.2.1.1) Complexed With 1'-Deazo-Thiamin Diphosphate And Calcium >gi|809443|pdb|1TKB|B Chain B, Transketolase (E.C.2.2.1.1) Complexed With 1'-Deazo-Thiamin Diphosphate And Calcium >gi|809440|pdb|1TKA|A Chain A, Transketolase (E.C.2.2.1.1) Complexed With 3'-Deazo-Thiamin Diphosphate And Calcium >gi|809441|pdb|1TKA|B Chain B, Transketolase (E.C.2.2.1.1) Complexed With 3'-Deazo-Thiamin Diphosphate And Calcium >gi|809444|pdb|1TKC|A Chain A, Transketolase (E.C.2.2.1.1) Complexed With 6'-Methyl-Thiamin Diphosphate And Calcium >gi|809445|pdb|1TKC|B Chain B, Transketolase (E.C.2.2.1.1) Complexed With 6'-Methyl-Thiamin Diphosphate And Calcium Length = 678 Score = 88.5 bits (216), Expect = 6e-17 Identities = 66/185 (35%), Positives = 94/185 (50%), Gaps = 16/185 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 D +LS GH+ Y ML G L EDL++F + P H LP +EV++G LGQ Sbjct: 59 DRFVLSNGHAVALLYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQ 118 Query: 103 GLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNV 152 G+S A G+AMA+ +V LGDG L EG EA+ A H L N+ Sbjct: 119 GISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNL 178 Query: 153 IAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGVKG 209 IAI D N + G T I E +A +++A+GW+V V+N ++ + + I + K Sbjct: 179 IAIYDDNKITIDGATS-ISFDEDVAKRYEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKD 237 Query: 210 KPKVI 214 KP +I Sbjct: 238 KPTLI 242 >pdb|1AY0|A Chain A, Identification Of Catalytically Important Residues In Yeast Transketolase >gi|3212469|pdb|1AY0|B Chain B, Identification Of Catalytically Important Residues In Yeast Transketolase Length = 680 Score = 88.5 bits (216), Expect = 6e-17 Identities = 66/185 (35%), Positives = 94/185 (50%), Gaps = 16/185 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 D +LS GH+ Y ML G L EDL++F + P H LP +EV++G LGQ Sbjct: 61 DRFVLSNGHAVALLYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQ 120 Query: 103 GLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNV 152 G+S A G+AMA+ +V LGDG L EG EA+ A H L N+ Sbjct: 121 GISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNL 180 Query: 153 IAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGVKG 209 IAI D N + G T I E +A +++A+GW+V V+N ++ + + I + K Sbjct: 181 IAIYDDNKITIDGATS-ISFDEDVAKRYEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKD 239 Query: 210 KPKVI 214 KP +I Sbjct: 240 KPTLI 244 >sp|Q12630|TKT1_KLULA TRANSKETOLASE (TK) >gi|1488336|gb|AAB05935.1| (U65983) transketolase [Kluyveromyces lactis] Length = 679 Score = 85.0 bits (207), Expect = 7e-16 Identities = 58/176 (32%), Positives = 88/176 (49%), Gaps = 13/176 (7%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 D +LS GH+ Y +L G + EDL+ F + P H LP +EV++G LGQ Sbjct: 61 DRFVLSNGHACALLYSLLHLFGYDMSIEDLKHFRHLGSKTPGHPEFELPGVEVTTGPLGQ 120 Query: 103 GLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDNV 152 G+S A G+A+A+ + +V LGDG L EG EA+ A H L N+ Sbjct: 121 GISNAVGMAIAQANFAATYNKPDYELSDSYTYVFLGDGCLQEGVSSEASSLAGHLRLKNL 180 Query: 153 IAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVK 208 IA D N + GN + E ++ +++A+GW+V V+N + L + L+ K Sbjct: 181 IAFYDDNQITIDGNI-NVSFDEDVSKRYEAYGWEVLHVENGNDDLDAISKALEQAK 235 >emb|CAB58135.1| (AJ249787) putative transketolase precursor [Cyanophora paradoxa] Length = 771 Score = 85.0 bits (207), Expect = 7e-16 Identities = 63/190 (33%), Positives = 100/190 (52%), Gaps = 24/190 (12%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADIDG-LPSH----VTRGLPFIEVSS 97 D +LS GH Y +L+ G + ED++ F + P H VT+G IEV++ Sbjct: 162 DRFVLSAGHGCMLQYALLYLTGYDSVGIEDIKTFRQWESECPGHPENFVTKG---IEVTT 218 Query: 98 GSLGQGLSVANGIAM-----AKRIDGKSGRV-----FVILGDGELDEGQIWEAAMTASHY 147 G LGQG++ A G+AM A R + ++ +VI+GDG EG EAA A HY Sbjct: 219 GPLGQGIAQAVGLAMGEAHLAARFNKPDVKLIDHYTYVIMGDGCNMEGVAAEAASLAGHY 278 Query: 148 GLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWK---VREVKNEVESLKEVINEL 204 GL N+IA+ D N + GNT+ I E + +++++GW V + ++ ++++ I E Sbjct: 279 GLGNLIALYDDNEISIDGNTD-ISFTEDVTKRYQSYGWHTVVVEDGNTDINAIRKAIAEA 337 Query: 205 DGVKGKPKVI 214 V KP ++ Sbjct: 338 KAVTDKPSLV 347 >gi|6319593 transketolase, homologous to tkl1; Tkl2p [Saccharomyces cerevisiae] >gi|464894|sp|P33315|TKT2_YEAST TRANSKETOLASE 2 (TK 2) >gi|481127|pir||S37809 transketolase (EC 2.2.1.1) TKL2 - yeast (Saccharomyces cerevisiae) >gi|313262|emb|CAA51937.1| (X73532) transketolase [Saccharomyces cerevisiae] >gi|476071|emb|CAA55619.1| (X78993) transketolase [Saccharomyces cerevisiae] >gi|536458|emb|CAA85074.1| (Z35985) ORF YBR117c [Saccharomyces cerevisiae] Length = 681 Score = 84.7 bits (206), Expect = 9e-16 Identities = 62/185 (33%), Positives = 91/185 (48%), Gaps = 16/185 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQ 102 D +LS GHS Y ML LG EDL +F ++ P H +E++SG LGQ Sbjct: 61 DRFVLSNGHSCALLYSMLHLLGYDYSIEDLRQFRQVNSRTPGHPEFHSAGVEITSGPLGQ 120 Query: 103 GLSVANGIAMAK-------RIDG---KSGRVFVILGDGELDEGQIWEAAMTASHYGLDNV 152 G+S A G+A+A+ DG F I+GDG L EG E + A H L N+ Sbjct: 121 GISNAVGMAIAQANFAATYNEDGFPISDSYTFAIVGDGCLQEGVSSETSSLAGHLQLGNL 180 Query: 153 IAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREV---KNEVESLKEVINELDGVKG 209 I D N + G T ++ L +++A+GW+V EV +++ES+ + + K Sbjct: 181 ITFYDSNSISIDGKTSYSFDEDVL-KRYEAYGWEVMEVDKGDDDMESISSALEKAKLSKD 239 Query: 210 KPKVI 214 KP +I Sbjct: 240 KPTII 244 >gb|AAC01739.1| (AF040571) transketolase [Amycolatopsis mediterranei] Length = 533 Score = 84.3 bits (205), Expect = 1e-15 Identities = 66/209 (31%), Positives = 99/209 (46%), Gaps = 20/209 (9%) Query: 20 NGFHMHSSLTCLSIL-QAVLEVKRSD------DVVILSKGHSAPAFYVMLWKLGLLRDED 72 +G+ S+L + +L + VL V S+ D LSKGH A+Y +L G + E Sbjct: 21 HGWAAASTLHAIWVLYERVLNVSPSNIDDPGRDRFYLSKGHGPMAYYAVLAAKGFIEPET 80 Query: 73 LEKFADIDG-LPSHVTRGL-PFIEVSSGSLGQGLSVANGIAMAKRIDGKSGRVFVILGDG 130 L+ + L H R L P +E+SSGSLG GL + G A+ R G+ RV V++GDG Sbjct: 81 LDTWRQWGSPLGMHPDRNLAPGVEISSGSLGHGLPLGVGTALGLRAQGRDARVVVLMGDG 140 Query: 131 ELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREV 190 E DEG E A GL ++ A+V + T + +A +++ GW V Sbjct: 141 EFDEGSNHETMAIAGRLGLGSLTAVV------IDNKTASLGWPGGIAGRFEQEGWAATTV 194 Query: 191 KNEVESL--KEVINELDGVKGKPKVIIAK 217 K + E D G+P+ +IA+ Sbjct: 195 DGRDHDALEKALTGETD---GRPRAVIAE 220 >pir||H70451 transketolase - Aquifex aeolicus >gi|2984067|gb|AAC07607.1| (AE000755) transketolase [Aquifex aeolicus] Length = 689 Score = 82.7 bits (201), Expect = 3e-15 Identities = 58/172 (33%), Positives = 95/172 (54%), Gaps = 16/172 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGL-PFIEVSSGSLG 101 D ILS GH + Y + G L EDL+ F ++ P H GL P +EV++G+LG Sbjct: 88 DRFILSAGHGSAMLYAAFYMFGFDLTLEDLKAFRQLNSKTPGHPEYGLTPGVEVTTGNLG 147 Query: 102 QGLSVANGIAMAKRI----DGKSGR------VFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG A G+AMA++ + G +V++ DG+L EG +EAA A H+ L+ Sbjct: 148 QGFGNAVGMAMAEKFLSHYFNREGYPVIDHYTYVLVSDGDLMEGVSYEAASLAGHFKLNK 207 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN--EVESLKEVI 201 +IAI D N+ + G+T ++ E + +++A GW+V +++ ++ L+E I Sbjct: 208 LIAIWDNNHITIDGDT-KLTWTEDVLKRFEALGWEVYHLEDGYNLDLLEETI 258 >sp|P34736|TKT_PICST TRANSKETOLASE (TK) >gi|480852|pir||S37439 transketolase (EC 2.2.1.1) - yeast (Pichia stipitis) >gi|403309|emb|CAA81260.1| (Z26486) transketolase [Pichia stipitis] Length = 695 Score = 81.9 bits (199), Expect = 6e-15 Identities = 61/186 (32%), Positives = 93/186 (49%), Gaps = 17/186 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTR-GLPFIEVSSGSLG 101 D +LS GH+ Y ML G L EDL+KF + P H +P EV++G LG Sbjct: 58 DRFVLSNGHACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLG 117 Query: 102 QGLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG+ GIA+A+ +V LGDG L EG EA+ A H L N Sbjct: 118 QGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGN 177 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGVK 208 +IA D N + G+TE +++ +A ++K++GW + EV + ++ ++ I+E V Sbjct: 178 LIAFWDDNKISIDGSTEVAFTEDVIA-RYKSYGWHIVEVSDADTDITAIAAAIDEAKKVT 236 Query: 209 GKPKVI 214 KP ++ Sbjct: 237 NKPTLV 242 >pir||T09541 transketolase (EC 2.2.1.1) TKT1 precursor, chloroplast [validated] - pepper >gi|3559814|emb|CAA75777.1| (Y15781) transketolase 1 [Capsicum annuum] Length = 744 Score = 81.5 bits (198), Expect = 7e-15 Identities = 64/187 (34%), Positives = 92/187 (48%), Gaps = 18/187 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADIDG-LPSHVTR-GLPFIEVSSGSL 100 D +LS GH Y +L G +R+EDL+ F P H P +EV++G L Sbjct: 138 DRFVLSAGHGCMLQYALLHLAGYDAVREEDLKSFRQWGSKTPGHPENFETPGVEVTTGPL 197 Query: 101 GQGLSVANGIAM-----AKRIDGKSGRV-----FVILGDGELDEGQIWEAAMTASHYGLD 150 GQG++ A G+A+ A R + + + ILGDG EG EAA A H+GL Sbjct: 198 GQGIANAVGLALSEKHLAARFNKPGAEIVDHYTYCILGDGCQMEGISQEAASLAGHWGLG 257 Query: 151 NVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGV 207 +IA D N+ + G+TE I E + +++A GW V VKN + ++ I E V Sbjct: 258 KLIAFYDDNHISIDGDTE-IAFTEDVGARFEALGWHVIWVKNGNTGYDEIRAAIKEAKAV 316 Query: 208 KGKPKVI 214 KP +I Sbjct: 317 TDKPTMI 323 >sp|O06811|TKT_MYCTU TRANSKETOLASE (TK) >gi|7433614|pir||D70917 probable tkt protein - Mycobacterium tuberculosis (strain H37RV) >gi|2131047|emb|CAB09272.1| (Z95844) tkt [Mycobacterium tuberculosis] Length = 700 Score = 81.1 bits (197), Expect = 1e-14 Identities = 62/188 (32%), Positives = 93/188 (48%), Gaps = 19/188 (10%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVT-RGLPFIEVSSGSLG 101 D +LS GHS+ Y+ L+ G L D+E P H R P +E+++G LG Sbjct: 77 DRFVLSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLG 136 Query: 102 QGLSVANGIAMAKRI-------DGKSGR------VFVILGDGELDEGQIWEAAMTASHYG 148 QGL+ A G+AMA R D + G ++VI DG+++EG EA+ A+ Sbjct: 137 QGLASAVGMAMASRYERGLFDPDAEPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQ 196 Query: 149 LDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK--NEVESLKEVINELDG 206 L N+I DRN + +T I E A +++A+GW V+EV+ V ++E I Sbjct: 197 LGNLIVFYDRNQISIEDDT-NIALCEDTAARYRAYGWHVQEVEGGENVVGIEEAIANAQA 255 Query: 207 VKGKPKVI 214 V +P I Sbjct: 256 VTDRPSFI 263 >pir||S77463 transketolase (EC 2.2.1.1) - Synechocystis sp. (strain PCC 6803) >gi|1652388|dbj|BAA17310.1| (D90905) transketolase [Synechocystis sp.] Length = 670 Score = 80.0 bits (194), Expect = 2e-14 Identities = 58/187 (31%), Positives = 99/187 (52%), Gaps = 18/187 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADIDG-LPSHVTRGLPF-IEVSSGSL 100 D +LS GH + Y +L+ LG + ED+++F + P H L +EV++G L Sbjct: 63 DRFVLSAGHGSMLQYALLYLLGYDSVTIEDIKQFRQWESSTPGHPENFLTAGVEVTTGPL 122 Query: 101 GQGLSVANGIAMAKRIDGKSGR----------VFVILGDGELDEGQIWEAAMTASHYGLD 150 GQG++ G+A+A+ + +VILGDG EG EAA A H+GL Sbjct: 123 GQGIANGVGLALAEAHLAATYNKPDATIVDHYTYVILGDGCNMEGISGEAASIAGHWGLG 182 Query: 151 NVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGV 207 +IA+ D N+ + G+T+ + E ++ +++A+GW V V++ ++ ++ + I E V Sbjct: 183 KLIALYDDNHISIDGSTD-VAFTEDVSKRFEAYGWHVLHVEDGNTDLAAIAKAIEEAKAV 241 Query: 208 KGKPKVI 214 KP +I Sbjct: 242 TDKPSMI 248 >sp|Q43848|TKTC_SOLTU TRANSKETOLASE, CHLOROPLAST PRECURSOR (TK) >gi|1658322|emb|CAA90427.1| (Z50099) transketolase precursor [Solanum tuberosum] Length = 741 Score = 80.0 bits (194), Expect = 2e-14 Identities = 61/187 (32%), Positives = 95/187 (50%), Gaps = 18/187 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADIDG-LPSHVTR-GLPFIEVSSGSL 100 D +LS GH Y +L G ++++DL+ F +P H P +EV++G L Sbjct: 135 DRFVLSAGHGCMLQYALLHLAGYDSVQEDDLKSFRQWGSRIPGHPENFETPGVEVTTGPL 194 Query: 101 GQGLSVANGIAMAK-----RIDGKSGRV-----FVILGDGELDEGQIWEAAMTASHYGLD 150 GQG++ A G+A+A+ R + + +VILGDG EG E A H+GL Sbjct: 195 GQGIANAVGLAVAEKHLAARFNKPDAEIVDHYTYVILGDGCQMEGISNEVCSLAGHWGLG 254 Query: 151 NVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGV 207 +IA D N+ + G+TE I E ++ ++++ GW V VKN + ++ I E V Sbjct: 255 KLIAFYDDNHISIDGDTE-IAFTEDVSARFESLGWHVIWVKNGNTGYDEIRAAIKEAKAV 313 Query: 208 KGKPKVI 214 K KP +I Sbjct: 314 KDKPTMI 320 >pir||S58083 transketolase (EC 2.2.1.1) precursor - potato (fragment) Length = 694 Score = 80.0 bits (194), Expect = 2e-14 Identities = 61/187 (32%), Positives = 95/187 (50%), Gaps = 18/187 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADIDG-LPSHVTR-GLPFIEVSSGSL 100 D +LS GH Y +L G ++++DL+ F +P H P +EV++G L Sbjct: 88 DRFVLSAGHGCMLQYALLHLAGYDSVQEDDLKSFRQWGSRIPGHPENFETPGVEVTTGPL 147 Query: 101 GQGLSVANGIAMAK-----RIDGKSGRV-----FVILGDGELDEGQIWEAAMTASHYGLD 150 GQG++ A G+A+A+ R + + +VILGDG EG E A H+GL Sbjct: 148 GQGIANAVGLAVAEKHLAARFNKPDAEIVDHYTYVILGDGCQMEGISNEVCSLAGHWGLG 207 Query: 151 NVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGV 207 +IA D N+ + G+TE I E ++ ++++ GW V VKN + ++ I E V Sbjct: 208 KLIAFYDDNHISIDGDTE-IAFTEDVSARFESLGWHVIWVKNGNTGYDEIRAAIKEAKAV 266 Query: 208 KGKPKVI 214 K KP +I Sbjct: 267 KDKPTMI 273 >pir||T47886 transketolase-like protein - Arabidopsis thaliana >gi|7329685|emb|CAB82679.1| (AL162295) transketolase-like protein [Arabidopsis thaliana] Length = 754 Score = 80.0 bits (194), Expect = 2e-14 Identities = 64/187 (34%), Positives = 93/187 (49%), Gaps = 18/187 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADIDG-LPSHVTR-GLPFIEVSSGSL 100 D +LS GH Y +L G +++EDL++F P H P IEV++G L Sbjct: 135 DRFVLSAGHGCMLLYALLHLAGYDSVQEEDLKQFRQWGSKTPGHPENFETPGIEVTTGPL 194 Query: 101 GQGLSVANGIAMAK-----RIDGKSGRV-----FVILGDGELDEGQIWEAAMTASHYGLD 150 GQG++ A G+A+A+ R + V + ILGDG EG EA A H+GL Sbjct: 195 GQGIANAVGLALAEKHLAARFNKPDAEVVDHYTYAILGDGCQMEGISNEACSLAGHWGLG 254 Query: 151 NVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGV 207 +IA D N+ + G+TE I E + +++A GW V VKN + ++ I E V Sbjct: 255 KLIAFYDDNHISIDGDTE-IAFTENVDQRFEALGWHVIWVKNGNTGYDEIRAAIKEAKTV 313 Query: 208 KGKPKVI 214 KP +I Sbjct: 314 TDKPTLI 320 >sp|P43757|TKT_HAEIN TRANSKETOLASE (TK) >gi|1075385|pir||G64108 transketolase (EC 2.2.1.1) - Haemophilus influenzae (strain Rd KW20) >gi|1574055|gb|AAC22683.1| (U32783) transketolase 1 (tktA) [Haemophilus influenzae Rd] Length = 665 Score = 79.6 bits (193), Expect = 3e-14 Identities = 64/188 (34%), Positives = 96/188 (51%), Gaps = 16/188 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGL-PFIEVSSGSLG 101 D +LS GH + Y +L G L EDL++F + P H G P +E ++G LG Sbjct: 58 DRFVLSNGHGSMLIYSLLHLTGYDLSIEDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLG 117 Query: 102 QGLSVANGIAMA-KRIDGKSGR---------VFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG++ A G+A+A K + G+ R +V LGDG L EG EA A GL Sbjct: 118 QGITNAVGMAIAEKTLAGQFNREGHEIVDHHTYVFLGDGCLMEGISHEACSLAGTLGLGK 177 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKV-REVK-NEVESLKEVINELDGVKG 209 +IA D N + G+ + S + A++++A+GW+V R V ++ E ++ KG Sbjct: 178 LIAFYDDNNISIDGHVDGWFS-DDTAERFEAYGWQVIRNVDGHDAEQIRAATILAQAEKG 236 Query: 210 KPKVIIAK 217 KP +II K Sbjct: 237 KPTLIICK 244 >emb|CAC18218.1| (AL451017) probable TRANSKETOLASE [Neurospora crassa] Length = 686 Score = 79.2 bits (192), Expect = 4e-14 Identities = 61/189 (32%), Positives = 95/189 (49%), Gaps = 17/189 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDGL-PSHV-TRGLPFIEVSSGSLG 101 D +LS GH+ Y +L G L +DL+ F ID + P H P +EV++G LG Sbjct: 62 DRFVLSNGHACMLQYALLHLYGYALTIDDLKAFRRIDSITPGHPEAHDTPGVEVTTGPLG 121 Query: 102 QGLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG+S A G+A+A+ D + + LGDG L EG EA A H L N Sbjct: 122 QGISNAVGLAIAQAHTAAVFNKPGYDLVNNYTYCFLGDGCLMEGVSSEACSLAGHLQLGN 181 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREV---KNEVESLKEVINELDGVK 208 +IAI D N + G+T + +++ L +++++GW + V N ++ + + I + V Sbjct: 182 LIAIWDDNRITIDGDTNQAFTEDVL-KRYESYGWHIVTVLDGDNNLDLIADAIKKAKEVT 240 Query: 209 GKPKVIIAK 217 KP +I K Sbjct: 241 DKPTLIQLK 249 >sp|Q42677|TKT7_CRAPL TRANSKETOLASE 7 (TK) >gi|1084441|pir||S54301 transketolase (EC 2.2.1.1) 7 - Craterostigma plantagineum >gi|664903|emb|CAA86609.1| (Z46648) transketolase [Craterostigma plantagineum] Length = 676 Score = 78.4 bits (190), Expect = 6e-14 Identities = 61/187 (32%), Positives = 95/187 (50%), Gaps = 18/187 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADIDG-LPSHVTR-GLPFIEVSSGSL 100 D +LS GH Y +L G +++EDL+ P+H P +EV++G L Sbjct: 68 DRFVLSAGHGCMLQYALLHLSGYDSVKEEDLKSLRQWGSRTPAHPENFETPGVEVTTGPL 127 Query: 101 GQGLSVANGIAMA-KRIDGKSGR---------VFVILGDGELDEGQIWEAAMTASHYGLD 150 GQG++ A G+A+A K + + + +VILGDG EG EA A+H+GL Sbjct: 128 GQGIASAVGLAVAEKHLAARYNKPGFEIVDHYTYVILGDGCQMEGVSNEACSLAAHWGLG 187 Query: 151 NVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEV---INELDGV 207 +IA+ D N+ + G+T+ + E + ++ A GW V VKN + E+ I E V Sbjct: 188 KLIALYDDNHITIDGDTD-VAFTEDVDKRFDALGWHVIWVKNGNDGCDEIRAAIEEAKSV 246 Query: 208 KGKPKVI 214 K +P +I Sbjct: 247 KDRPTMI 253 >sp|P46708|TKT_MYCLE TRANSKETOLASE (TK) >gi|2145978|pir||S72772 transketolase (EC 2.2.1.1) tkt - Mycobacterium leprae >gi|466894|gb|AAA17139.1| (U00013) tkt; B1496_F1_26 [Mycobacterium leprae] >gi|2398717|emb|CAB16182.1| (Z99125) transketolase [Mycobacterium leprae] Length = 699 Score = 77.6 bits (188), Expect = 1e-13 Identities = 60/188 (31%), Positives = 92/188 (48%), Gaps = 19/188 (10%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDGL-PSHVT-RGLPFIEVSSGSLG 101 D +LS GHS+ Y+ L+ G L D+E P H R +E+++G LG Sbjct: 77 DRFVLSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSTTPGHPEFRHTKGVEITTGPLG 136 Query: 102 QGLSVANGIAMAKRI-------DGKSGR------VFVILGDGELDEGQIWEAAMTASHYG 148 QGL+ A G+AMA R D + G ++VI DG+++EG EA+ A+ Sbjct: 137 QGLASAVGMAMASRYERGLFDPDAEPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQ 196 Query: 149 LDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK--NEVESLKEVINELDG 206 L N+I D N + G+T +I E A +++A+GW V+EV+ V ++E I Sbjct: 197 LGNLIVFYDHNQISIEGDT-KITLCEDTAARYRAYGWHVQEVEGGENVVGIEEAIANAKA 255 Query: 207 VKGKPKVI 214 +P I Sbjct: 256 ATDRPSFI 263 >pir||T40162 transketolase - fission yeast (Schizosaccharomyces pombe) >gi|3850070|emb|CAA21881.1| (AL033385) transketolase [Schizosaccharomyces pombe] Length = 685 Score = 77.3 bits (187), Expect = 1e-13 Identities = 62/190 (32%), Positives = 89/190 (46%), Gaps = 18/190 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGLPF--IEVSSGSL 100 D ILS GH+ Y+M LG L EDL++F + P H P IE +G L Sbjct: 64 DRFILSNGHACVLQYIMCHLLGYKLTIEDLKQFRQVGSKTPGHPETHNPDLNIETGAGPL 123 Query: 101 GQGLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLD 150 GQG++ A G+A+ K D S F LGDG L EG EA A H L Sbjct: 124 GQGIASAVGLAIGKAHSAAVYNKPGFDLFSNYTFCFLGDGCLQEGVSSEACSLAGHLKLS 183 Query: 151 NVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGV 207 N+IA+ D N + G T + E + +++A+GW + V N +++ +++ E Sbjct: 184 NLIAVWDNNKITIDGATS-MSFDEDVEKRFEAYGWNIVRVANGDTDLDGIEKGFREAMSC 242 Query: 208 KGKPKVIIAK 217 KP +I K Sbjct: 243 TDKPTLINLK 252 >pir||T18231 transketolase I - yeast (Candida albicans) >gi|3859715|emb|CAA21989.1| (AL033501) transketolase I [Candida albicans] Length = 677 Score = 77.3 bits (187), Expect = 1e-13 Identities = 62/190 (32%), Positives = 96/190 (49%), Gaps = 25/190 (13%) Query: 45 DVVILSKGHSAPAFY--VMLWKLGLLRDEDLEKFADID-GLPSHV----TRGLPFIEVSS 97 D +LS GH+ Y ++L+K L D DL++F + P H T G +EV++ Sbjct: 58 DRFVLSNGHACALLYSLLVLYKFELTVD-DLKQFRQLGFKTPGHPEATDTAG---VEVTT 113 Query: 98 GSLGQGLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHY 147 G LGQG+S A GIA+A++ I V+ +GDG L EG E + A H Sbjct: 114 GPLGQGISNAVGIAIAQKQFAATYNKPDITLSDSYVYTFVGDGCLMEGVSSETSSLAGHL 173 Query: 148 GLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREV---KNEVESLKEVINEL 204 L+N+IA D N + G+T + E + D+++A+GW V EV +E++ ++E Sbjct: 174 QLNNLIAFWDDNRISIDGDT-AVSFTENVPDRYRAYGWNVLEVPDANTNIEAIAAAVDEA 232 Query: 205 DGVKGKPKVI 214 KP +I Sbjct: 233 KKSTDKPTLI 242 >gb|AAA35168.1| (M63302) transkelotase [Saccharomyces cerevisiae] Length = 678 Score = 76.9 bits (186), Expect = 2e-13 Identities = 53/139 (38%), Positives = 73/139 (52%), Gaps = 13/139 (9%) Query: 71 EDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQGLSVANGIAMA-----------KRIDG 118 EDL++F + P H LP +EV++G LGQG+S A G+AMA + Sbjct: 88 EDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVGMAMAQANLDMPLTTSRAFTL 147 Query: 119 KSGRVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLAD 178 +V LGDG L EG EA+ A H L N+IAI D N + G T I E +A Sbjct: 148 SDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNLIAIYDDNKITIDGATS-ISFDEDVAK 206 Query: 179 KWKAFGWKVREVKNEVESL 197 +++A+GW+V V+N E L Sbjct: 207 RYEAYGWEVLYVENGNEDL 225 >sp|Q42675|TKTA_CRAPL TRANSKETOLASE 10 (TK) >gi|1084439|pir||S54299 transketolase (EC 2.2.1.1) 10 - Craterostigma plantagineum >gi|664899|emb|CAA86608.1| (Z46647) transketolase [Craterostigma plantagineum] Length = 679 Score = 76.9 bits (186), Expect = 2e-13 Identities = 61/191 (31%), Positives = 93/191 (47%), Gaps = 26/191 (13%) Query: 45 DVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDGL-------PSHVTR-GLPFIEVS 96 D +LS GH A Y +L G D K D+ GL P+H P +EV+ Sbjct: 72 DRFVLSAGHGAMLLYGLLHLAGY----DSVKVEDLKGLRQWGSKTPAHPENFETPGVEVT 127 Query: 97 SGSLGQGLSVANGIAMAKRIDGKSGR----------VFVILGDGELDEGQIWEAAMTASH 146 +G LGQG+ A G+A+A++ G ++ILGDG EG EA+ A+H Sbjct: 128 TGPLGQGVGSAVGLALAEKHLGARYNKPDFEMVDHYTYMILGDGCQMEGISNEASSLAAH 187 Query: 147 YGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINE 203 +GL +IA+ D N+ + G+T+ + E + +++A GW V V N + ++E I Sbjct: 188 WGLGKLIALYDDNHITIDGDTD-LAFTEDVGKRFEALGWHVLTVANGNDGYDEIREAIKV 246 Query: 204 LDGVKGKPKVI 214 V KP +I Sbjct: 247 AKSVTDKPTLI 257 >pir||H81737 transketolase TC0131 [imported] - Chlamydia muridarum (strain Nigg) >gi|7190167|gb|AAF39009.1| (AE002280) transketolase [Chlamydia muridarum] Length = 666 Score = 76.9 bits (186), Expect = 2e-13 Identities = 60/186 (32%), Positives = 91/186 (48%), Gaps = 15/186 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVT-RGLPFIEVSSGSLG 101 D +LS GH + Y L G +R EDL++F + P H R +E ++G LG Sbjct: 66 DRFVLSAGHGSALLYSCLHLAGFNVRLEDLQQFRQLHSQTPGHPEFRETDGVEATTGPLG 125 Query: 102 QGLSVANGIAMAKRIDGK----------SGRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG+ A G+A++ ++ G +V+ + GDG EG EA A GLDN Sbjct: 126 QGIGNAVGMALSLKMLGSRFNQSSTSIFDAKVYCLAGDGCFMEGVSHEACSFAGSLGLDN 185 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK-NEVESLKEVINELDGVKGK 210 +I I D N L G + + S E ++ A+GW V E ++ E L V +++ + K Sbjct: 186 LILIYDYNEIILDGTLQDV-SVEDTKQRFLAYGWDVFEANGHDFEDLHRVFSQIKKGQQK 244 Query: 211 PKVIIA 216 P +IIA Sbjct: 245 PTLIIA 250 >pir||T09015 transketolase (EC 2.2.1.1) precursor, chloroplast - spinach >gi|2529342|gb|AAD10219.1| (L76554) transketolase [Spinacia oleracea] Length = 741 Score = 76.5 bits (185), Expect = 2e-13 Identities = 62/187 (33%), Positives = 92/187 (49%), Gaps = 18/187 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADIDG-LPSHVTR-GLPFIEVSSGSL 100 D +LS GH Y +L G + +EDL+ F +P H P +EV++G L Sbjct: 135 DRFVLSAGHGCMLQYALLHLAGYDSVLEEDLKTFRQWGSRIPGHPENFETPGVEVTTGPL 194 Query: 101 GQGLSVANGIAMAK-----RIDGKSGRV-----FVILGDGELDEGQIWEAAMTASHYGLD 150 GQG++ A G+A+A+ R + + +VILGDG EG EA A H+GL Sbjct: 195 GQGIANAVGLALAEKHLAARFNKPDAEIVDHYTYVILGDGCQMEGIAQEACSLAGHWGLG 254 Query: 151 NVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN---EVESLKEVINELDGV 207 +IA D N+ + G+T I E + +++A GW V VKN + ++ I E V Sbjct: 255 KLIAFYDDNHISIDGDT-AIAFTESVDLRFEALGWHVIWVKNGNTGYDEIRAAIKEAKTV 313 Query: 208 KGKPKVI 214 KP +I Sbjct: 314 TDKPTLI 320 >dbj|BAA74963.1| (AB023377) transketolase [Corynebacterium glutamicum] Length = 676 Score = 76.5 bits (185), Expect = 2e-13 Identities = 66/207 (31%), Positives = 101/207 (47%), Gaps = 25/207 (12%) Query: 32 SILQAVLEVKRSD------DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDGL-P 83 ++ Q V+ V D D +LS GHS+ Y+ L+ G L +DL+ D L P Sbjct: 37 TLYQRVMNVDPQDTNWAGRDRFVLSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTP 96 Query: 84 SHVT-RGLPFIEVSSGSLGQGLSVANGIAMAKR----------IDGKSG---RVFVILGD 129 H R +E+++G LGQGL+ A G+AMA R +G+S ++VI D Sbjct: 97 GHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDPTAAEGESPFDHHIYVIASD 156 Query: 130 GELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVRE 189 G+L EG EA+ A L N+I D N + NTE I E + ++KA+GW+ E Sbjct: 157 GDLQEGVTSEASSIAGTQQLGNLIVFWDDNRISIEDNTE-IAFNEDVVARYKAYGWQTIE 215 Query: 190 VK--NEVESLKEVINELDGVKGKPKVI 214 V+ +V +++ + E +P I Sbjct: 216 VEAGEDVAAIEAAVAEAKKDTKRPTFI 242 >pir||T36007 probable transketolase - Streptomyces coelicolor >gi|5459402|emb|CAB50760.1| (AL096839) probable transketolase [Streptomyces coelicolor A3(2)] Length = 695 Score = 76.5 bits (185), Expect = 2e-13 Identities = 58/162 (35%), Positives = 83/162 (50%), Gaps = 17/162 (10%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRG-LPFIEVSSGSLG 101 D +LS GHS+ Y L+ G L DLE F P H G +E ++G LG Sbjct: 70 DRFVLSAGHSSLTLYTQLYLAGFGLELADLESFRTWGSKTPGHPEYGHTTGVETTTGPLG 129 Query: 102 QGLSVANGIAMAKRID----------GKSGR---VFVILGDGELDEGQIWEAAMTASHYG 148 QG++ A G+AMA R + G+S V+ I GDG L EG EA+ TA H Sbjct: 130 QGVANAVGMAMAARYERGLFDPEAAEGESPFDHFVYCIAGDGCLQEGISSEASSTAGHQK 189 Query: 149 LDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREV 190 L N++ + D N+ + G+TE +S E +++A+GW V+ V Sbjct: 190 LGNLVLLWDDNHISIEGDTETAVS-EDTCKRYEAYGWHVQRV 230 >dbj|BAB06071.1| (AP001515) transketolase [Bacillus halodurans] Length = 666 Score = 76.5 bits (185), Expect = 2e-13 Identities = 60/174 (34%), Positives = 88/174 (50%), Gaps = 16/174 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRG-LPFIEVSSGSLG 101 D +LS GH + Y +L G L E+L+ F P H G P +E ++G LG Sbjct: 60 DRFVLSAGHGSMLLYSLLHLTGYDLSLEELQNFRQWGSKTPGHPEYGHTPGVEATTGPLG 119 Query: 102 QGLSVANGIAMAKRI-------DGKS---GRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG+++A G+AMA+R DG + + I GDG+L EG EAA A H L Sbjct: 120 QGVAMAVGMAMAERHLAATYNRDGYNIVDHYTYTICGDGDLMEGVSAEAASLAGHLKLGR 179 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK--NEVESLKEVINE 203 +I + D N L G+ S E + D++KA+GW V V+ N ++ + + I E Sbjct: 180 MILLYDSNDISLDGDLHHSFS-ESVEDRFKAYGWHVVRVEDGNNLDEIAKAIEE 232 >pir||JC7146 transketolase (EC 2.2.1.1) - Corynebacterium glutamicum Length = 700 Score = 76.5 bits (185), Expect = 2e-13 Identities = 66/207 (31%), Positives = 101/207 (47%), Gaps = 25/207 (12%) Query: 32 SILQAVLEVKRSD------DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDGL-P 83 ++ Q V+ V D D +LS GHS+ Y+ L+ G L +DL+ D L P Sbjct: 61 TLYQRVMNVDPQDTNWAGRDRFVLSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTP 120 Query: 84 SHVT-RGLPFIEVSSGSLGQGLSVANGIAMAKR----------IDGKSG---RVFVILGD 129 H R +E+++G LGQGL+ A G+AMA R +G+S ++VI D Sbjct: 121 GHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDPTAAEGESPFDHHIYVIASD 180 Query: 130 GELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVRE 189 G+L EG EA+ A L N+I D N + NTE I E + ++KA+GW+ E Sbjct: 181 GDLQEGVTSEASSIAGTQQLGNLIVFWDDNRISIEDNTE-IAFNEDVVARYKAYGWQTIE 239 Query: 190 VK--NEVESLKEVINELDGVKGKPKVI 214 V+ +V +++ + E +P I Sbjct: 240 VEAGEDVAAIEAAVAEAKKDTKRPTFI 266 >pir||C71475 probable transketolase - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3329211|gb|AAC68345.1| (AE001347) Transketolase [Chlamydia trachomatis] Length = 666 Score = 75.3 bits (182), Expect = 6e-13 Identities = 60/186 (32%), Positives = 91/186 (48%), Gaps = 15/186 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVT-RGLPFIEVSSGSLG 101 D +LS GH + Y L G + EDL++F + P H R +E ++G LG Sbjct: 66 DRFVLSAGHGSALLYSCLHLAGFDVNLEDLQQFRQLQSRTPGHPEFRETDGVEATTGPLG 125 Query: 102 QGLSVANGIAMAKRIDGK----------SGRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG+ A G+A++ ++ G +V+ + GDG EG EA A GLDN Sbjct: 126 QGVGNAVGMALSLKMLGARFNQPANSIFDAKVYCLAGDGCFMEGVSHEACSFAGSLGLDN 185 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK-NEVESLKEVINELDGVKGK 210 ++ I D N L G T +S E ++ A+GW V E ++ ESL +V ++ + K Sbjct: 186 LVLIYDHNEIILDG-TLHDVSIEDTKQRFLAYGWDVFETDGHDFESLHQVFTQIKKSQCK 244 Query: 211 PKVIIA 216 P +IIA Sbjct: 245 PTLIIA 250 >gb|AAB82634.1| (AC002387) putative transketolase precursor [Arabidopsis thaliana] Length = 741 Score = 74.9 bits (181), Expect = 7e-13 Identities = 60/187 (32%), Positives = 90/187 (48%), Gaps = 18/187 (9%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADIDG-LPSHVTR-GLPFIEVSSGSL 100 D +LS GH Y +L G +R+EDL+ F P H P +E ++G L Sbjct: 135 DRFVLSAGHGCMLQYALLHLAGYDSVREEDLKSFRQWGSKTPGHPENFETPGVEATTGPL 194 Query: 101 GQGLSVANGIAMAK-----RIDGKSGRV-----FVILGDGELDEGQIWEAAMTASHYGLD 150 GQG++ A G+A+A+ R + + + ILGDG EG E A H+GL Sbjct: 195 GQGIANAVGLALAEKHLAARFNKPDNEIVDHYTYSILGDGCQMEGISNEVCSLAGHWGLG 254 Query: 151 NVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK---NEVESLKEVINELDGV 207 +IA D N+ + G+T+ I E + +++A GW V VK N + ++ I E V Sbjct: 255 KLIAFYDDNHISIDGDTD-IAFTESVDKRFEALGWHVIWVKNGNNGYDEIRAAIREAKAV 313 Query: 208 KGKPKVI 214 KP +I Sbjct: 314 TDKPTLI 320 >sp|P33570|TKT2_ECOLI TRANSKETOLASE 2 (TK 2) >gi|477312|pir||A48660 transketolase (EC 2.2.1.1) B - Escherichia coli >gi|460975|dbj|BAA02039.1| (D12473) transketolase [Escherichia coli] >gi|1788808|gb|AAC75518.1| (AE000333) transketolase 2 isozyme [Escherichia coli K12] >gi|1799889|dbj|BAA16340.1| (D90875) transketolase (EC 2.2.1.1) [Escherichia coli] Length = 667 Score = 74.1 bits (179), Expect = 1e-12 Identities = 61/188 (32%), Positives = 92/188 (48%), Gaps = 16/188 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGL-PFIEVSSGSLG 101 D ILS GH++ Y +L G L E+L+ F + P H G P +E ++G LG Sbjct: 57 DRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLG 116 Query: 102 QGLSVANGIAMAKRIDGKSGR----------VFVILGDGELDEGQIWEAAMTASHYGLDN 151 QGL+ A G+A+A+R +V +GDG L EG E A GL Sbjct: 117 QGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEGISHEVCSLAGTLGLGK 176 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKV-REVK-NEVESLKEVINELDGVKG 209 +I D N + G TE + + A +++A+ W V E+ ++ +++KE I E VK Sbjct: 177 LIGFYDHNGISIDGETEGWFT-DDTAKRFEAYHWHVIHEIDGHDPQAVKEAILEAQSVKD 235 Query: 210 KPKVIIAK 217 KP +II + Sbjct: 236 KPSLIICR 243 >sp|P06834|DAS_PICAN DIHYDROXY-ACETONE SYNTHASE (DHAS) (FORMALDEHYDE TRANSKETOLASE) (GLYCERONE SYNTHASE) >gi|418622|pir||XJHQFK formaldehyde transketolase (EC 2.2.1.3) - yeast (Pichia angusta) >gi|5263|emb|CAA26276.1| (X02424) DHAS [Pichia angusta] Length = 710 Score = 73.7 bits (178), Expect = 2e-12 Identities = 53/176 (30%), Positives = 86/176 (48%), Gaps = 16/176 (9%) Query: 45 DVVILSKGHSAPAFYVM--LWKLGLLRDEDLEKFADIDG---LPSHVTRGLPFIEVSSGS 99 D +LS GH Y+ L+ L + L+ + D P H +EV++G Sbjct: 70 DRFVLSNGHVCLFQYIFQHLYGLKSMTMAQLKSYHSNDFHSLCPGHPEIEHDAVEVTTGP 129 Query: 100 LGQGLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHYGL 149 LGQG+S + G+A+A + D + +V+ ++GD L EG E+ A H GL Sbjct: 130 LGQGISNSVGLAIATKNLAATYNKPGFDIITNKVYCMVGDACLQEGPALESISLAGHMGL 189 Query: 150 DNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELD 205 DN+I + D N G+ + I + E ++ K+KA W V EV+N E + ++ L+ Sbjct: 190 DNLIVLYDNNQVCCDGSVD-IANTEDISAKFKACNWNVIEVENASEDVATIVKALE 244 >pir||H64655 transketolase A - Helicobacter pylori (strain 26695) >gi|2314236|gb|AAD08131.1| (AE000615) transketolase A (tktA) [Helicobacter pylori 26695] Length = 641 Score = 73.4 bits (177), Expect = 2e-12 Identities = 61/187 (32%), Positives = 94/187 (49%), Gaps = 21/187 (11%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADID----GLPS-HVTRGLPFIEVSSG 98 D ++ S GH++ Y +L G L EDL++F + G P H T G IE+++G Sbjct: 64 DRLVFSGGHASALAYSLLHLWGFDLSLEDLKRFRQLHSKTPGHPELHHTEG---IEITTG 120 Query: 99 SLGQGLSVANGIAMAKRI-------DGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 LGQG + A G +MA + + S +V+ + GDG+L EG +E+A A H LDN Sbjct: 121 PLGQGFANAVGFSMASQYAQNLLDKEAISHKVYCLCGDGDLQEGISYESASLAGHLRLDN 180 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVK--G 209 +I I D N + G I E + ++ A W+V E + + + N L+ K Sbjct: 181 LIVIYDSNQISIEG-AINISFSEQVKTRFVAQNWEVLEC--DGHDYQAIHNALEEAKKST 237 Query: 210 KPKVIIA 216 KP ++IA Sbjct: 238 KPTLLIA 244 >sp|P46374|FAS2_RHOFA FERREDOXIN FAS2 >gi|1076044|pir||B55578 ferredoxin 2[4Fe-4S]-related protein - Rhodococcus fascians plasmid >gi|455002|emb|CAA82742.1| (Z29635) ferredoxine [Rhodococcus fascians] Length = 304 Score = 73.0 bits (176), Expect = 3e-12 Identities = 48/116 (41%), Positives = 65/116 (55%), Gaps = 5/116 (4%) Query: 45 DVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADID---GLPSHVTRGLPFIEVSSGSLG 101 D +LSKGH A+Y +L G LR E L+ +A + G T+ + +E+S GSLG Sbjct: 123 DRFLLSKGHGPMAYYAVLAAKGFLRPELLDTWATKNSPLGFAPDRTK-ISGVEMSGGSLG 181 Query: 102 QGLSVANGIAMAKRIDGKSG-RVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIV 156 GL +A G+AM RI + RVFV++GDGE DEG EA A L+ + IV Sbjct: 182 HGLPLAVGVAMGLRIQNRHAPRVFVLIGDGEFDEGSNHEAMAFAGRARLNQLTVIV 237 >emb|CAB82464.1| (AJ132348) transketolase, putative [Staphylococcus aureus] Length = 571 Score = 73.0 bits (176), Expect = 3e-12 Identities = 57/187 (30%), Positives = 92/187 (48%), Gaps = 16/187 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGLLRDEDLEKFADIDG-LPSHVT-RGLPFIEVSSGSLGQ 102 D +LS GH + Y +L G L E+L++F P H R +EV++G LGQ Sbjct: 60 DRFVLSAGHGSALLYSLLHVSGSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQ 119 Query: 103 GLSVANGIAMAK-RIDGKSGR---------VFVILGDGELDEGQIWEAAMTASHYGLDNV 152 G +++ G+A+A+ + GK + +V+ DG+L EG EAA A H L + Sbjct: 120 GFAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLMEGISHEAASFAGHNKLSKL 179 Query: 153 IAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK--NEVESLKEVINELDGVKGK 210 + + D N L G + S+ A +++A+GW VK N++E + + I +G Sbjct: 180 VVLYDSNDISLDGELNKAFSENTKA-RFEAYGWNYLLVKDGNDLEEIDKAITTAKSQEG- 237 Query: 211 PKVIIAK 217 P +I K Sbjct: 238 PTIIEVK 244 >sp|P75611|TKT_MYCPN TRANSKETOLASE (TK) >gi|2146671|pir||S73399 transketolase (EC 2.2.1.1) 1 - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1673726|gb|AAB95721.1| (AE000009) transketolase 1 [Mycoplasma pneumoniae] Length = 648 Score = 72.6 bits (175), Expect = 4e-12 Identities = 48/171 (28%), Positives = 84/171 (49%), Gaps = 13/171 (7%) Query: 45 DVVILSKGHSAPAFYVMLWKLGLLRDEDL--EKFADIDGLPSHVTRGLPFIEVSSGSLGQ 102 D +++S GH + A Y +L GL+ +++ K+ ++ FI+ S+G LGQ Sbjct: 54 DRLVMSAGHGSMALYPILHFAGLITKQEMLHHKYGQVNTSSHPEYAPNNFIDASTGPLGQ 113 Query: 103 GLSVANGIAMAKRIDGKSGRV----------FVILGDGELDEGQIWEAAMTASHYGLDNV 152 GL +A G+A+ +R+ + +V++GDG+L EG +E A A Y L+ + Sbjct: 114 GLGMAVGMALTQRVLAAEFKALSPKLFDHFTYVVVGDGDLQEGVSYEVAHLAGVYQLNKL 173 Query: 153 IAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINE 203 I + D N Q+ + R +S E L ++ GW E + V + I + Sbjct: 174 IVLHDSNRVQMD-SVVRDVSLENLQTRFTNMGWNYLETSDAVADIDAAIKQ 223 >gb|AAA96741.1| (U29134) transketolase [Xanthobacter flavus] Length = 687 Score = 71.8 bits (173), Expect = 6e-12 Identities = 59/188 (31%), Positives = 89/188 (46%), Gaps = 16/188 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGL-PFIEVSSGSLG 101 D +LS GH + Y +L G L +L++F + P H G+ P +E ++G LG Sbjct: 79 DRFVLSNGHGSMLIYALLHLTGYDLPIAELKRFRQLHSRTPGHPELGMTPGVETTTGPLG 138 Query: 102 QGLSVANGIAMAKR----------IDGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 QGL+ A G+A+A++ + R FV LGDG L EG EA A GL Sbjct: 139 QGLANAVGMAIAEKTLAAQFNRPGLSIVDHRTFVFLGDGCLMEGVSHEACSLAGRLGLGK 198 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKV-REVK-NEVESLKEVINELDGVKG 209 ++A D N + G E + A ++ A+GW V R V ++ L++ + G Sbjct: 199 LVAFYDDNGISIDGKVEEWFPDDTPA-RFAAYGWHVIRNVDGHDPAMLRDAVEAALSETG 257 Query: 210 KPKVIIAK 217 KP +I K Sbjct: 258 KPTLICCK 265 >sp|P45694|TKT_BACSU TRANSKETOLASE >gi|7433610|pir||G69723 transketolase (EC 2.2.1.1) tkt - Bacillus subtilis >gi|1405446|emb|CAA97616.1| (Z73234) transketolase [Bacillus subtilis] >gi|2634173|emb|CAB13673.1| (Z99113) transketolase [Bacillus subtilis] Length = 667 Score = 71.0 bits (171), Expect = 1e-11 Identities = 60/188 (31%), Positives = 91/188 (47%), Gaps = 16/188 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRG-LPFIEVSSGSLG 101 D +LS GH + Y ML G L EDL+ F P H G ++ ++G LG Sbjct: 59 DRFVLSAGHGSALLYSMLHLSGFDLSIEDLKGFRQWGSKTPGHPEFGHTAGVDATTGPLG 118 Query: 102 QGLSVANGIAMAKRIDGKSGR----------VFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG+++A G+A+A+R ++ + I GDG+L EG EAA A H L Sbjct: 119 QGIAMAVGMAIAERHLAETYNRDSFNVVDHYTYSICGDGDLMEGISSEAASLAGHLQLGR 178 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK--NEVESLKEVINELDGVKG 209 +I + D N L G+ +R S E + +++A W+V V+ N +E L I + + Sbjct: 179 LIVLYDSNDISLDGDLDRSFS-ENVKQRFEAMNWEVLYVEDGNNIEELTAAIEKARQNEK 237 Query: 210 KPKVIIAK 217 KP +I K Sbjct: 238 KPTLIEVK 245 >pir||T35162 transketolase - Streptomyces coelicolor >gi|3334794|emb|CAA19942.1| (AL031107) transketolase [Streptomyces coelicolor A3(2)] Length = 698 Score = 71.0 bits (171), Expect = 1e-11 Identities = 55/192 (28%), Positives = 94/192 (48%), Gaps = 23/192 (11%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRG-LPFIEVSSGSLG 101 D +LS GH++ Y L+ G + +DL+ F P H G +E ++G LG Sbjct: 76 DRFVLSPGHTSLTLYTQLFLAGYEVELDDLKAFRTHGSRTPGHPEYGHTAGVETTTGPLG 135 Query: 102 QGLSVANGIAMAKRID----------GKSG---RVFVILGDGELDEGQIWEAAMTASHYG 148 QG++ A G+AMA R + G+S ++ I+ DG+L EG EA+ A H Sbjct: 136 QGVANAVGMAMAARYERGLFDPEAPEGESPFDHTIWAIVSDGDLQEGVSAEASSLAGHQK 195 Query: 149 LDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN------EVESLKEVIN 202 L N++ + D N+ + G+T S++ L +++A+GW + V+ +V +L + Sbjct: 196 LGNLVFLYDDNHISIEGDTVTAFSEDVL-KRYEAYGWHTQRVEPAESGDVDVRALHAAMT 254 Query: 203 ELDGVKGKPKVI 214 G+P +I Sbjct: 255 AAKAETGRPSII 266 >pir||D71944 transketolase - Helicobacter pylori (strain J99) >gi|4154867|gb|AAD05919.1| (AE001469) transketolase [Helicobacter pylori J99] Length = 641 Score = 71.0 bits (171), Expect = 1e-11 Identities = 59/187 (31%), Positives = 93/187 (49%), Gaps = 21/187 (11%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADID----GLPS-HVTRGLPFIEVSSG 98 D ++ S GH++ Y +L G L +DL++F + G P H T G IE+++G Sbjct: 64 DRLVFSGGHASALVYSLLHLWGFDLSLDDLKRFRQLHSKTPGHPELHHTEG---IEITTG 120 Query: 99 SLGQGLSVANGIAMAKRI-------DGKSGRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 LGQG + A G +MA + + S +V+ + GDG+L EG +E+ A H LDN Sbjct: 121 PLGQGFANAVGFSMASQYAQTLLDKEAISHKVYCLCGDGDLQEGISYESTSLAGHLRLDN 180 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELDGVK--G 209 +I I D N + G I E + ++ A W+V E + + + N L+ K Sbjct: 181 LIVIYDSNQISIEG-AINISFSEQVKTRFLAQNWEVLEC--DGHDYQAIHNALEEAKKSH 237 Query: 210 KPKVIIA 216 KP ++IA Sbjct: 238 KPTLLIA 244 >gb|AAC83349.1| (AF086822) dihydroxyacetone synthase [Candida boidinii] Length = 706 Score = 70.2 bits (169), Expect = 2e-11 Identities = 53/188 (28%), Positives = 89/188 (47%), Gaps = 19/188 (10%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADID---GLPSHVTRGLPFIEVSSGS 99 D +LS GH Y+ GL + ++ L+ + D P H +EV++G Sbjct: 68 DRFVLSNGHVCLFQYLFQHLSGLKSMTEKQLKSYHSSDYHSKCPGHPEIENEAVEVTTGP 127 Query: 100 LGQGLSVANGIAMAKRIDGK----------SGRVFVILGDGELDEGQIWEAAMTASHYGL 149 LGQG+S + G+A+A + G + + I+GD L EG E+ A H GL Sbjct: 128 LGQGISNSVGLAIASKNLGALYNKPGYEVVNNTTYCIVGDACLQEGPALESISFAGHLGL 187 Query: 150 DNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVINELD---G 206 DN++ I D N G+ + I + E ++ K++A W V EV++ + ++ L+ Sbjct: 188 DNLVVIYDNNQVCCDGSVD-IANTEDISAKFRACNWNVIEVEDGARDVATIVKALELAGA 246 Query: 207 VKGKPKVI 214 K +P +I Sbjct: 247 EKNRPTLI 254 >pir||C81261 transketolase (EC 2.2.1.1) Cj1645 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6969062|emb|CAB73633.1| (AL139079) transketolase [Campylobacter jejuni] Length = 632 Score = 69.1 bits (166), Expect = 4e-11 Identities = 65/224 (29%), Positives = 105/224 (46%), Gaps = 23/224 (10%) Query: 14 DMLRPVNGFHMHSSLTCLSILQAV-LEVKRSD--------DVVILSKGHSAPAFYVMLWK 64 DM++ N H + L IL + +K + D ++ S GH++ Y L Sbjct: 19 DMVQKANSGHPGAPLGLADILSVLSYHLKHNPKNPTWLNRDRLVFSGGHASALLYSFLHL 78 Query: 65 LGL-LRDEDLEKFADIDG-LPSHVTRGLPFIEVSSGSLGQGLSVANGIAMA-KRIDGKSG 121 G L EDL+ F + P H +E+++G LGQG++ A G AMA K+ G Sbjct: 79 SGYDLSLEDLKNFRQLHSKTPGHPEISTLGVEIATGPLGQGVANAVGFAMAAKKAQNLLG 138 Query: 122 ------RVFVILGDGELDEGQIWEAAMTASHYGLDNVIAIVDRNYGQLSGNTERIMSKEP 175 +++ + GDG+L EG +EA A + LDN I I D N + G+ + E Sbjct: 139 SDLIDHKIYCLCGDGDLQEGISYEACSLAGLHKLDNFILIYDSNNISIEGDV-GLAFNEN 197 Query: 176 LADKWKAFGWKVREVKNEVESLKEVINELDGVK--GKPKVIIAK 217 + +++A G++V + +E+ L+ K KP +IIAK Sbjct: 198 VKMRFEAQGFEVLSING--HDYEEINKALEQAKKSTKPCLIIAK 239 >pir||B81082 transketolase NMB1457 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226698|gb|AAF41816.1| (AE002495) transketolase [Neisseria meningitidis MC58] Length = 659 Score = 68.7 bits (165), Expect = 5e-11 Identities = 56/188 (29%), Positives = 90/188 (47%), Gaps = 16/188 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGLPF-IEVSSGSLG 101 D +LS GH++ Y +L G L EDL+ F + P H G +E ++G LG Sbjct: 55 DRFVLSNGHASMLLYSLLHLTGYNLSIEDLKNFRQLHSKTPGHPEYGYTDGVETTTGPLG 114 Query: 102 QGLSVANGIAMAKRI-------DGKS---GRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG++ A G+A+A++I DG + +V +GDG L EG EA A GL Sbjct: 115 QGIANAVGMALAEKILAAEFNKDGLNIVDHYTYVFMGDGCLMEGVSHEACSLAGTLGLGK 174 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN--EVESLKEVINELDGVKG 209 +I + D N + G + + E + +++++GW V N + +++ I G Sbjct: 175 LIVLYDDNNISIDGKVDGWFT-ENIPQRFESYGWHVVPNVNGHDTAAIQAAIEAARAETG 233 Query: 210 KPKVIIAK 217 KP +I K Sbjct: 234 KPSIICCK 241 >pir||A81862 transketolase (EC 2.2.1.1) NMA1669 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7380311|emb|CAB84897.1| (AL162756) transketolase [Neisseria meningitidis Z2491] Length = 659 Score = 68.7 bits (165), Expect = 5e-11 Identities = 56/188 (29%), Positives = 90/188 (47%), Gaps = 16/188 (8%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL-LRDEDLEKFADIDG-LPSHVTRGLPF-IEVSSGSLG 101 D +LS GH++ Y +L G L EDL+ F + P H G +E ++G LG Sbjct: 55 DRFVLSNGHASMLLYSLLHLTGYNLSIEDLKNFRQLHSKTPGHPEYGYTDGVETTTGPLG 114 Query: 102 QGLSVANGIAMAKRI-------DGKS---GRVFVILGDGELDEGQIWEAAMTASHYGLDN 151 QG++ A G+A+A++I DG + +V +GDG L EG EA A GL Sbjct: 115 QGIANAVGMALAEKILAAEFNKDGLNIVDHYTYVFMGDGCLMEGVSHEACSLAGTLGLGK 174 Query: 152 VIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKN--EVESLKEVINELDGVKG 209 +I + D N + G + + E + +++++GW V N + +++ I G Sbjct: 175 LIVLYDDNNISIDGKVDGWFT-ENIPQRFESYGWHVVPNVNGHDTAAIQAAIEAARAETG 233 Query: 210 KPKVIIAK 217 KP +I K Sbjct: 234 KPSIICCK 241 >sp|P47312|TKT_MYCGE TRANSKETOLASE (TK) >gi|1361873|pir||C64207 transketolase (EC 2.2.1.1) - Mycoplasma genitalium >gi|1045741|gb|AAC71284.1| (U39686) transketolase (tktA) [Mycoplasma genitalium] Length = 648 Score = 67.9 bits (163), Expect = 9e-11 Identities = 43/169 (25%), Positives = 83/169 (48%), Gaps = 13/169 (7%) Query: 45 DVVILSKGHSAPAFYVMLWKLGLLRDEDL--EKFADIDGLPSHVTRGLPFIEVSSGSLGQ 102 D +LS GH + A Y + GL+ +++ K I+ FI+ S+G LGQ Sbjct: 54 DRFVLSAGHGSMALYSIFHFAGLISKQEILQHKHGQINTSSHPEYAPNNFIDASTGPLGQ 113 Query: 103 GLSVANGIAMAKRIDGKSGR----------VFVILGDGELDEGQIWEAAMTASHYGLDNV 152 G +A G+ +A+++ + +V++GDG+L EG +E + A Y L+ + Sbjct: 114 GFGMAVGMVLAQKLLANEFKELSDKLFDHYTYVVVGDGDLQEGVSYEVSQIAGLYKLNKL 173 Query: 153 IAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVKNEVESLKEVI 201 I + D N Q+ +++ + E L +++ GW +++E++ + I Sbjct: 174 IVLHDSNRVQMDSEVKKV-ANENLKVRFENVGWNYIHTDDQLENIDQAI 221 >pir||H75295 transketolase - Deinococcus radiodurans (strain R1) >gi|6460061|gb|AAF11802.1|AE002058_2 (AE002058) transketolase [Deinococcus radiodurans] Length = 666 Score = 67.9 bits (163), Expect = 9e-11 Identities = 58/189 (30%), Positives = 95/189 (49%), Gaps = 23/189 (12%) Query: 45 DVVILSKGHSAPAFYVMLWKLGL--LRDEDLEKFADID-GLPSHV----TRGLPFIEVSS 97 D +LS GH++ Y +L G + +DL F P H T+GL + ++ Sbjct: 65 DRFVLSAGHASMLIYSLLHLTGYQEMTLDDLRHFRQWGYHTPGHPEFFHTKGL---DATT 121 Query: 98 GSLGQGLSVANGIAMAK-----RIDGKS-----GRVFVILGDGELDEGQIWEAAMTASHY 147 G LGQG ++ G+AMA+ R + + R + I+GDG+L EG EAA A H Sbjct: 122 GPLGQGAAMTVGMAMAEAHLAARYNREGFPIFDNRTYAIMGDGDLQEGINHEAAALAGHL 181 Query: 148 GLDNVIAIVDRNYGQLSGNTERIMSKEPLADKWKAFGWKVREVK--NEVESLKEVINELD 205 L +I + D N+ QL T + S E A +++A+GW V +V+ + ++ +++ I E Sbjct: 182 KLGKLIWLHDDNHIQLDTPTNKAES-EDTAARFRAYGWNVLKVEDGDNLDEIEKAIAEAR 240 Query: 206 GVKGKPKVI 214 +P +I Sbjct: 241 SQSERPTLI 249 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.318 0.137 0.400 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82479094 Number of Sequences: 2977 Number of extensions: 3328220 Number of successful extensions: 9124 Number of sequences better than 1.0e-10: 69 Number of HSP's better than 0.0 without gapping: 8 Number of HSP's successfully gapped in prelim test: 61 Number of HSP's that attempted gapping in prelim test: 9003 Number of HSP's gapped (non-prelim): 70 length of query: 220 length of database: 189,106,746 effective HSP length: 54 effective length of query: 166 effective length of database: 156,788,448 effective search space: 26026882368 effective search space used: 26026882368 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 163 (67.9 bits)