BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0296 (tkt2) DE:transketolase C-TERMINAL SECTION
(317 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75161 transketolase c-terminal section PAB0296 - Pyrococcu... 620 e-177
gb|AAK40639.1| Transketolase, C-terminal section (tkt-2) [Sulfol... 310 1e-83
emb|CAC11756.1| (AL445064) probable transketolase [Thermoplasma ... 269 3e-71
sp|Q58092|TKTC_METJA PUTATIVE TRANSKETOLASE C-TERMINAL SECTION (... 256 3e-67
pir||G72643 probable transketolase APE0583 - Aeropyrum pernix (s... 243 2e-63
sp|P55573|Y4MN_RHISN HYPOTHETICAL TRANSKETOLASE FAMILY PROTEIN Y... 191 7e-48
pir||T34727 transketolase - Streptomyces coelicolor >gi|3861429|... 168 6e-41
pir||D81034 1-deoxyxylulose-5-phosphate synthase NMB1867 [import... 165 5e-40
pir||T20473 hypothetical protein F01G10.1 - Caenorhabditis elega... 165 7e-40
pir||B81978 probable 1-deoxyxylulose-5-phosphate synthase NMA058... 162 6e-39
gb|AAF76194.1| (AF270484) transketolase [Xenopus laevis] 160 2e-38
gi|6678359 transketolase [Mus musculus] >gi|730956|sp|P40142|TKT... 160 2e-38
gb|AAG28459.1|AF195533_1 (AF195533) transketolase [Mus musculus] 160 2e-38
pir||A45050 transketolase (EC 2.2.1.1) - human >gi|37267|emb|CAA... 159 4e-38
gi|4507521 transketolase (Wernicke-Korsakoff syndrome) [Homo sap... 158 7e-38
sp|P50137|TKT_RAT TRANSKETOLASE (TK) 158 7e-38
gb|AAA18026.1| (U09256) transketolase [Rattus norvegicus] 158 7e-38
pir||PH0845 transketolase (EC 2.2.1.1) - human (fragment) 158 7e-38
gb|AAA61222.1| (L12711) transketolase [Homo sapiens] 157 2e-37
sp|O67036|DXS_AQUAE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SY... 157 2e-37
emb|CAB60078.1| (Y18874) 1-deoxy-xylulose 5-phosphate synthase [... 157 2e-37
gb|AAF54265.1| (AE003680) CG8036 gene product [Drosophila melano... 153 2e-36
dbj|BAB06498.1| (AP001516) 1-deoxyxylulose-5-phosphate synthase ... 153 3e-36
sp|P73067|DXS_SYNY3 PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHAS... 152 5e-36
pir||G75390 1-deoxy-D-xylulose-5-phosphate synthase - Deinococcu... 147 1e-34
gi|7110727 transketolase-like 1; Transketolase-2 [Homo sapiens] ... 146 3e-34
gb|AAF49267.1| (AE003521) CG5103 gene product [Drosophila melano... 146 4e-34
sp|P45205|DXS_HAEIN 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SY... 145 5e-34
dbj|BAA74730.1| (AB016786) transketolase [Ascidia sydneiensis sa... 142 6e-33
sp|P77488|DXS_ECOLI 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SY... 141 8e-33
pir||H82266 1-deoxyxylulose-5-phosphate synthase VC0889 [importe... 141 1e-32
sp|P54523|DXS_BACSU PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHAS... 141 1e-32
pir||G83139 1-deoxyxylulose-5-phosphate synthase PA4044 [importe... 140 2e-32
pir||T34693 hypothetical protein SC1C3.01 SC1C3.01 - Streptomyce... 139 3e-32
pir||T35408 probable transketolase - Streptomyces coelicolor >gi... 138 7e-32
dbj|BAA85847.1| (AB026631) 1-deoxy-D-xylulose 5-phosphate syntha... 136 3e-31
dbj|BAA76702.1| (AB023411) Orf462d [Deinococcus radiodurans] 136 4e-31
sp|O07184|DXS_MYCTU PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHAS... 134 1e-30
sp|P57536|DXS_BUCAI 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SY... 132 5e-30
sp|Q9X291|DXS_THEMA 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SY... 132 6e-30
gb|AAA62954.1| (U15181) transketolase [Mycobacterium leprae] 131 1e-29
sp|Q50000|DXS_MYCLE PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHAS... 131 1e-29
pir||B72215 hypothetical protein TM1762 - Thermotoga maritima (s... 131 1e-29
pir||A82582 deoxyxylulose-5-phosphate synthase XF2249 [imported]... 125 5e-28
pir||F71527 probable transketolase - Chlamydia trachomatis (sero... 125 8e-28
pir||A72002 1-deoxyxylulose-5-phosphate synthase CP0790 [importe... 123 2e-27
pir||B71276 probable transketolase B (tktB) - syphilis spirochet... 122 4e-27
pir||E81684 1-deoxyxylulose-5-phosphate synthase TC0608 [importe... 121 1e-26
sp|P26242|DXS_RHOCA PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHAS... 120 2e-26
dbj|BAA99999.1| (AB019232) 1-deoxyxylulose-5-phosphate synthase;... 119 4e-26
emb|CAC08458.1| (AJ279019) 1-D-desoxyxylulose 5-phosphate syntha... 118 1e-25
sp|Q38854|CLA1_ARATH PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHA... 116 2e-25
emb|CAA74713.1| (Y14333) transketolase [Arabidopsis thaliana] 116 2e-25
emb|CAB45992.1| (Z97339) DEF (CLA1) protein [Arabidopsis thalian... 116 2e-25
emb|CAA09804.1| (AJ011840) 1-deoxyxylulose 5-phosphate synthase ... 116 3e-25
pir||T08140 1-deoxy-D-xylulose-5-phosphate synthase precursor - ... 115 7e-25
emb|CAB96673.1| (AL360314) 1-D-deoxyxylulose 5-phosphate synthas... 114 1e-24
pir||E81451 1-deoxyxylulose-5-phosphate synthase Cj0321 [importe... 114 2e-24
gb|AAC33513.1| (AF019383) 1-deoxyxylulose-5-phosphate synthase [... 113 2e-24
gb|AAD38941.1|AF143812_1 (AF143812) 1-D-deoxyxylulose 5-phosphat... 111 8e-24
pir||T09543 deoxyxylulose synthase (EC 2.2.1.-) TKT2 precursor, ... 110 2e-23
dbj|BAB04496.1| (AP001509) acetoin dehydrogenase (TPP-dependent)... 109 4e-23
gb|AAG10432.1| (AF251020) 1-deoxy-D-xylulose-5-phosphate synthas... 108 7e-23
sp|O22567|CLA1_ORYSA PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHA... 108 9e-23
pir||H71946 1-deoxyxylulose-5-phosphate synthase - Helicobacter ... 108 1e-22
emb|CAC17468.1| (AJ291721) 1-D-deoxyxylulose 5-phosphate synthas... 108 1e-22
pir||B64564 transketolase B - Helicobacter pylori (strain 26695)... 105 6e-22
dbj|BAA83576.1| (AP000399) ESTs AU078063(S15496),C97608(C60475),... 105 6e-22
dbj|BAB06373.1| (AP001516) pyruvate dehydrogenase E1 (lipoamide)... 105 8e-22
gb|AAK41604.1| Pyruvate dehydrogenase, beta subunit (lipoamide).... 104 1e-21
gb|AAD56390.2|AF182286_1 (AF182286) 1-deoxy-D-xylulose-5-phospha... 104 1e-21
dbj|BAB03933.1| (AP001507) pyruvate dehydrogenase E1 (lipoamide)... 101 1e-20
gb|AAF36410.1|AF235026_1 (AF235026) pyruvate dehydrogenase beta ... 101 2e-20
pir||T44306 pyruvate dehydrogenase (lipoamide) (EC 1.2.4.1) E1 b... 98 1e-19
sp|P21874|ODPB_BACST PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA S... 95 1e-18
pir||B70973 probable TRANSKETOLASE-LIKE PROTEIN - Mycobacterium ... 95 1e-18
sp|P37941|ODBB_BACSU 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT... 94 2e-18
sp|P21882|ODPB_BACSU PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA S... 93 5e-18
pir||A83128 acetoin catabolism protein AcoB PA4151 [imported] - ... 91 1e-17
sp|Q9ZDR3|ODPB_RICPR PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA S... 90 3e-17
sp|O34591|ACOB_BACSU ACETOIN:2,6-DICHLOROPHENOLINDOPHENOL OXIDOR... 89 7e-17
dbj|BAB06481.1| (AP001516) branched-chain alpha-keto acid dehydr... 89 7e-17
gb|AAG38098.1|AF299324_2 (AF299324) pyruvate dehydrogenase beta ... 89 9e-17
sp|P27746|ACOB_ALCEU ACETOIN:2,6-DICHLOROPHENOLINDOPHENOL OXIDOR... 88 1e-16
pir||I40791 acetoin dehydrogenase (TPP-dependent) (EC 1.-.-.-) b... 88 2e-16
gb|AAC72192.1| (AF069908) pyruvate dehydrogenase E1 beta subunit... 87 3e-16
gb|AAC72193.1| (AF069909) pyruvate dehydrogenase E1 beta subunit... 87 3e-16
gb|AAC01739.1| (AF040571) transketolase [Amycolatopsis mediterra... 86 4e-16
sp|Q38799|ODPB_ARATH PYRUVATE DEHYDROGENASE E1 COMPONENT BETA SU... 85 8e-16
sp|P52904|ODPB_PEA PYRUVATE DEHYDROGENASE E1 COMPONENT BETA SUBU... 85 8e-16
dbj|BAA98121.1| (AB026637) pyruvate dehydrogenase E1 component b... 85 8e-16
gb|AAK41749.1| Pyruvate dehydrogenase, beta subunit (lipoamide).... 85 1e-15
pir||T36497 probable branched-chain alpha keto acid dehydrogenas... 85 1e-15
gb|AAF04588.1|AF190792_2 (AF190792) pyruvate dehydrogenase beta ... 85 1e-15
sp|Q9R9N4|ODPB_RHIME PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA S... 85 1e-15
gb|AAC72194.1| (AF069910) pyruvate dehydrogenase E1 beta subunit... 84 2e-15
gi|4557353 branched chain keto acid dehydrogenase E1, beta polyp... 84 2e-15
pdb|1DTW|B Chain B, Human Branched-Chain Alpha-Keto Acid Dehydro... 84 2e-15
emb|CAC12557.1| (AL445067) probable 3-methyl-2-oxobutanoate dehy... 83 3e-15
emb|CAA36685.1| (X52446) E1b-beta precursor (AA -31 to 342) [Hom... 83 4e-15
dbj|BAB05542.1| (AP001513) acetoin dehydrogenase E1 component (T... 82 7e-15
pir||T46885 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (E... 82 1e-14
sp|P21839|ODBB_BOVIN 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT... 81 1e-14
pir||C81683 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (E... 81 1e-14
gb|AAC13740.1| (U00985) acetoin:DCPIP oxidoreductase beta subuni... 81 2e-14
pir||S39807 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (E... 81 2e-14
pir||H75295 transketolase - Deinococcus radiodurans (strain R1) ... 80 3e-14
gb|AAA51410.1| (M81742) branched chain alpha-keto acid dehydroge... 80 4e-14
pir||S28950 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (E... 80 4e-14
pir||C36953 acetoin[2,6-dichlorophenolindophenol] oxidoreductase... 79 6e-14
emb|CAA48166.1| (X68025) transketolase [Escherichia coli] >gi|88... 79 8e-14
gb|AAC38844.1| (AF013755) pyruvate dehydrogenase testis-specific... 79 8e-14
sp|P27302|TKT1_ECOLI TRANSKETOLASE 1 (TK 1) >gi|7427898|pir||XJE... 79 8e-14
pir||H83219 probable pyruvate dehydrogenase E1 component, beta c... 78 1e-13
pir||H72128 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (E... 78 1e-13
sp|P35488|ODPB_ACHLA PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA S... 78 2e-13
pir||T21454 hypothetical protein F27D4.5 - Caenorhabditis elegan... 77 2e-13
gb|AAD55378.1|AF149712_6 (AF149712) TPP-dependent branched-chain... 77 2e-13
gb|AAG20345.1| (AE005108) pyruvate dehydrogenase beta subunit; P... 77 2e-13
pir||G71526 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (E... 77 3e-13
gb|AAF35281.1|AF145452_1 (AF145452) branched chain alpha-keto ac... 77 3e-13
gb|AAG21455.1|AC021894_15 (AC021894) branched chain alpha-keto a... 77 3e-13
sp|P35738|ODBB_RAT 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, ... 76 4e-13
gi|6319698 beta subunit of pyruvate dehydrogenase (E1 beta); Pdb... 75 9e-13
gi|11465732 pyruvate dehydrogenase E1 component, beta subunit [P... 75 9e-13
pir||T51835 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (E... 75 9e-13
gb|AAD10651.1| (AC005223) branched-chain alpha-keto acid decarbo... 75 9e-13
gb|AAA34583.1| (M98476) pyruvate dehydrogenase E1-beta subunit [... 75 9e-13
pir||T36511 probable branched-chain alpha keto acid dehydrogenas... 75 1e-12
pir||E82872 transketolase I UU586 [imported] - Ureaplasma urealy... 74 2e-12
pir||S77342 probable pyruvate dehydrogenase (lipoamide) (EC 1.2.... 73 3e-12
pir||D71420 hypothetical protein - Arabidopsis thaliana 73 4e-12
sp|P46375|FAS3_RHOFA HYPOTHETICAL 33.6 KD PROTEIN IN FASCIATION ... 73 4e-12
pir||F72548 probable pyruvate dehydrogenase E1 component, beta s... 72 7e-12
gb|AAB58980.1| (L35343) TPP-dependent acetoin dehydrogenase beta... 72 1e-11
sp|P57195|TKT_BUCAI TRANSKETOLASE (TK) >gi|10038778|dbj|BAB12813... 71 1e-11
gb|AAF45391.1| (AE003270) CG17691 gene product [Drosophila melan... 71 2e-11
gb|AAC83349.1| (AF086822) dihydroxyacetone synthase [Candida boi... 70 4e-11
gb|AAC04864.1| (AF047336) transketolase [Drosophila heteroneura] 69 6e-11
pir||T50967 probable pyruvate dehydrogenase (lipoamide) beta cha... 69 6e-11
gb|AAD03740.2| (AF111814) 1-deoxy-D-xylulose 5-phosphate synthas... 69 8e-11
>pir||A75161 transketolase c-terminal section PAB0296 - Pyrococcus abyssi
(strain Orsay) >gi|5457878|emb|CAB49368.1| (AJ248284)
transketolase C-TERMINAL SECTION [Pyrococcus abyssi]
Length = 317
Score = 620 bits (1582), Expect = e-177
Identities = 317/317 (100%), Positives = 317/317 (100%)
Query: 1 MIESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGT 60
MIESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGT
Sbjct: 1 MIESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGT 60
Query: 61 AAGLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLE 120
AAGLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLE
Sbjct: 61 AAGLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLE 120
Query: 121 DIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKA 180
DIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKA
Sbjct: 121 DIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKA 180
Query: 181 NILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNL 240
NILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNL
Sbjct: 181 NILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNL 240
Query: 241 VITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYS 300
VITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYS
Sbjct: 241 VITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYS 300
Query: 301 KVLEVVKNEDDEVLEGV 317
KVLEVVKNEDDEVLEGV
Sbjct: 301 KVLEVVKNEDDEVLEGV 317
>gb|AAK40639.1| Transketolase, C-terminal section (tkt-2) [Sulfolobus solfataricus]
Length = 313
Score = 310 bits (786), Expect = 1e-83
Identities = 154/308 (50%), Positives = 219/308 (71%), Gaps = 2/308 (0%)
Query: 2 IESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTA 61
I S RE+FGR L ++G KNKD++V+ ADV +ST+ +YF +F DR+ VGI+EQDM+ A
Sbjct: 6 IYSMRETFGRLLADLGDKNKDLVVITADVGDSTRALYFREKFKDRYFNVGIAEQDMVNFA 65
Query: 62 AGLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLED 121
AGLA GK P + F FLMRAWEQIRN+IAR NL+VK+ TH+G+SD DGSSHQ LED
Sbjct: 66 AGLAAVGKKPAIVNFGMFLMRAWEQIRNSIARMNLDVKMFVTHTGYSDHGDGSSHQVLED 125
Query: 122 IALMRVLPNMKVVVPADAY-ATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGD-EIKLGK 179
IALMRVLPNMKVVVPAD R+L I E+ GP Y R+GR+++P + + E K+GK
Sbjct: 126 IALMRVLPNMKVVVPADPKDIERSLPVIINEERGPLYYRIGREYSPPITIGQEYEFKIGK 185
Query: 180 ANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVN 239
A +++DGSD+ + +GV++ AL+ AE L+ +GI V+++ ++KP+DE T+ ARK
Sbjct: 186 AYVIKDGSDLAIIGAGVVLWDALKAAEELEKLGISVAVINLFSIKPIDENTIEYYARKAG 245
Query: 240 LVITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVY 299
+IT+EEH+I+GG+G AVAE + + P + +G+TTFGRS+R LLD Y ++ +
Sbjct: 246 KIITIEEHSIYGGIGSAVAEVTARRYPVPIRFVGATTFGRSARSQRDLLDYYNINYKTII 305
Query: 300 SKVLEVVK 307
+ ++++K
Sbjct: 306 REAIDLLK 313
>emb|CAC11756.1| (AL445064) probable transketolase [Thermoplasma acidophilum]
Length = 316
Score = 269 bits (680), Expect = 3e-71
Identities = 135/311 (43%), Positives = 206/311 (65%), Gaps = 2/311 (0%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
ES R+ +G+ LV++G ++D++V+DAD+ +STKT YF N FPDRF +GISEQ M+ TAA
Sbjct: 4 ESLRDVYGKELVKLGSFDRDIVVLDADLSSSTKTGYFANAFPDRFFNMGISEQSMVTTAA 63
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
GLA++GK P VS FA FL R +EQIR ++ +N V+ V TH G + DG++HQ +ED+
Sbjct: 64 GLALSGKKPFVSTFAIFLTRTYEQIRQSVCYNNAPVRFVVTHGGITVGEDGATHQIVEDV 123
Query: 123 ALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANI 182
+M LPNM V+VPAD+ TR+++ + P Y+RL R+ P + ++ E K+GK+
Sbjct: 124 GIMAGLPNMNVIVPADSVETRSVVDYLAGVDKPHYVRLSREKFPVINDEDYEFKIGKSKT 183
Query: 183 LRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
+RDG+D+ +A GVMVS +LE AE+LK G+DA V++M ++KP D +I A++ ++
Sbjct: 184 IRDGADLTIIADGVMVSKSLEAAESLKKNGVDARVINMSSIKPTDRDAIIKAAKETGHIV 243
Query: 243 TLEEHTIFGGLGGAVAEALSEKMPRRVIRIG-STTFGRSSRDYLSLLDRYGLSVNKVYSK 301
T EEH+I+ GLG VAE SE P V RIG TFG+S + + L + + V + ++
Sbjct: 244 TAEEHSIYNGLGSRVAEITSESYPVPVRRIGMRDTFGKSGKAW-ELFSYFHMDVKDIINE 302
Query: 302 VLEVVKNEDDE 312
+ ++ ++ E
Sbjct: 303 AMTCLEEKNYE 313
>sp|Q58092|TKTC_METJA PUTATIVE TRANSKETOLASE C-TERMINAL SECTION (TK)
>gi|2129318|pir||G64384 transketolase (EC 2.2.1.1) -
Methanococcus jannaschii >gi|1591394|gb|AAB98674.1|
(U67515) transketolase'' [Methanococcus jannaschii]
Length = 316
Score = 256 bits (647), Expect = 3e-67
Identities = 137/312 (43%), Positives = 202/312 (63%), Gaps = 9/312 (2%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+ R+ +G TL+E+G+K ++++V+DAD+ ST+T F +FP+RF G++EQ+MIG AA
Sbjct: 9 KGMRKGYGETLIELGKKYENLVVLDADLSGSTQTAMFAKEFPERFFNAGVAEQNMIGMAA 68
Query: 63 GLAIAGKIPIVSAFAAFLM-RAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLED 121
GLA GKI S+F+ F RAWE IRN +A LNVKIVATH+G + DG+SHQ ED
Sbjct: 69 GLATTGKIVFASSFSMFASGRAWEIIRNLVAYPKLNVKIVATHAGITVGEDGASHQMCED 128
Query: 122 IALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDE--IKLGK 179
IA+MR +PNM V+ P D Y T+ ++ I E GP Y+R+ R +YE+ +E ++GK
Sbjct: 129 IAIMRAIPNMVVIAPTDYYHTKNVIRTIAEYKGPVYVRMPRRDTEIIYENEEEATFEIGK 188
Query: 180 ANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVN 239
IL DG D+ +A+G V AL E LK GI A +++M T+KP+DE + + +
Sbjct: 189 GKILVDGEDLTIIATGEEVPEALRAGEILKENGISAEIVEMATIKPIDEEI---IKKSKD 245
Query: 240 LVITLEEHTIFGGLGGAVAEAL-SEKMPRRVIRIG-STTFGRSSRDYLSLLDRYGLSVNK 297
V+T+E+H+I GGLGGAVAE + S + ++++RIG + FGRS + LL YGL
Sbjct: 246 FVVTVEDHSIIGGLGGAVAEVIASNGLNKKLLRIGINDVFGRSGKAD-ELLKYYGLDGES 304
Query: 298 VYSKVLEVVKNE 309
+ +++E +K E
Sbjct: 305 IAKRIMEEMKKE 316
>pir||G72643 probable transketolase APE0583 - Aeropyrum pernix (strain K1)
>gi|5104236|dbj|BAA79551.1| (AP000060) 322aa long
hypothetical transketolase [Aeropyrum pernix]
Length = 322
Score = 243 bits (613), Expect = 2e-63
Identities = 139/305 (45%), Positives = 191/305 (62%), Gaps = 6/305 (1%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+R++ GR L + + +D++V+DAD ST + P R + +GISEQD+IGTAAG
Sbjct: 11 SYRKALGRLLARLASELEDLVVLDADTLRSTGAIEVYRSAPRRVLNMGISEQDLIGTAAG 70
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
+A+AG P+V+ F AFLMR WEQIRNT+ RD LNVKIVATH+G S +DGSSHQ LED+A
Sbjct: 71 IALAGLRPVVTGFGAFLMRGWEQIRNTVDRDGLNVKIVATHTGLSPHVDGSSHQVLEDLA 130
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDH-GPAYMRLGRDFAPRVY-EDGDEIKLGKAN 181
LMR L V PAD AT + +V + GPAY+RLGRD A RVY E+ + G
Sbjct: 131 LMRSLARTAVFSPADDVATVETVEWLVRRYRGPAYVRLGRDNAFRVYSEEEFTFRPGGGE 190
Query: 182 IL-RDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNL 240
+L G + +A+G MV V+L A L+ G+ GV+D++++KP R ++ A + L
Sbjct: 191 VLVEPGEAVTLLATGPMVGVSLAAAALLRSEGLRVGVVDVYSIKPAPRRLVLEAAERSRL 250
Query: 241 VITLEEHTIFGGLGGAVAEALSEK-MPRRVIRIG--STTFGRSSRDYLSLLDRYGLSVNK 297
++T+EEH GGLG V+ L+E+ R RIG +G SSRDY+SLL L
Sbjct: 251 LVTVEEHRTVGGLGDVVSSILAEEGACARQARIGVPPGVYGSSSRDYMSLLRHLRLDPES 310
Query: 298 VYSKV 302
V ++V
Sbjct: 311 VAARV 315
>sp|P55573|Y4MN_RHISN HYPOTHETICAL TRANSKETOLASE FAMILY PROTEIN Y4MN
>gi|2182531|gb|AAB91777.1| (AE000085) Y4mN [Rhizobium
sp. NGR234]
Length = 345
Score = 191 bits (481), Expect = 7e-48
Identities = 121/301 (40%), Positives = 169/301 (55%), Gaps = 6/301 (1%)
Query: 9 FGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAG 68
FG L + K+ V+ + AD+ T F PDRF Q+G++EQ ++ +AAG+A G
Sbjct: 42 FGHALSALAEKDDRVVGLSADLAKYTDLHVFRAAHPDRFYQMGMAEQLLMMSAAGMAREG 101
Query: 69 KIPIVSAFAAFLMR-AWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRV 127
P V+ +A F R A++ I IA + L+VK+V G + G SHQ EDIA+ R
Sbjct: 102 LQPWVTTYAVFASRRAYDFICLAIAEEMLDVKVVCALPGLTTGY-GPSHQATEDIAMFRG 160
Query: 128 LPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYED-GDEIKLGKANILRDG 186
+PN+ ++ P DA + I GP YMRL R P V E+ G +LGKA +LRDG
Sbjct: 161 MPNLTIIDPCDASEIEQAVPAIAAHEGPVYMRLLRGNVPLVLEEYGYRFELGKAKLLRDG 220
Query: 187 SDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLI-NLARKVNLVITLE 245
D L ++SG+M ALE AE L+ GIDAGVL + T+KPLDE T++ AR+ LV+ E
Sbjct: 221 RDTLIISSGLMTMRALEAAEELRKNGIDAGVLHVPTIKPLDEATILAECARQGRLVVVAE 280
Query: 246 EHTIFGGLGGAVAEAL--SEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSKVL 303
HT+ GGLG AVA L S P +IG + +L D YG+S K+ +++
Sbjct: 281 NHTVIGGLGEAVAATLMRSAVRPAAFRQIGLPDAFLEAGALPTLHDMYGISTTKIVAQIK 340
Query: 304 E 304
E
Sbjct: 341 E 341
>pir||T34727 transketolase - Streptomyces coelicolor >gi|3861429|emb|CAA22034.1|
(AL033505) transketolase [Streptomyces coelicolor A3(2)]
Length = 615
Score = 168 bits (422), Expect = 6e-41
Identities = 94/279 (33%), Positives = 154/279 (54%), Gaps = 4/279 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R +FG L +G DV+ +D +V +ST+ +F + P+R+ + I+EQ M+ A G+A
Sbjct: 308 RNAFGEALAAVGTARGDVVALDGEVGDSTRAEFFAKEHPERYFECYIAEQQMVAAAVGMA 367
Query: 66 IAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALM 125
G +P + FAAFL RA++ +R + + +V +H+G + DG S LED+A+M
Sbjct: 368 ARGWVPFATTFAAFLTRAYDFVR-MASISGAGINLVGSHAGVAIGQDGPSQMGLEDLAMM 426
Query: 126 RVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR- 184
R + V+ P DA L+ E+ G Y+R R + +Y +E +G + +LR
Sbjct: 427 RAIHGSTVLYPCDANQAARLVAEMAGLEGIRYLRTSRGESKVIYGPDEEFPVGGSKVLRS 486
Query: 185 -DGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVIT 243
D + VA+GV + AL A+ L GI V+D+++VKP+D TL A + ++T
Sbjct: 487 SDADRLTVVAAGVTLHEALAAADALGADGIPVRVIDLYSVKPVDRATLRAAAEETGCLVT 546
Query: 244 LEEHTIFGGLGGAVAEALSEKMP-RRVIRIGSTTFGRSS 281
+E+H GG+G AV +A S+ P R++R+ TT S+
Sbjct: 547 VEDHRREGGIGDAVLDAFSDGRPVPRLVRLAVTTMPGSA 585
>pir||D81034 1-deoxyxylulose-5-phosphate synthase NMB1867 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7227124|gb|AAF42201.1| (AE002536)
1-deoxyxylulose-5-phosphate synthase [Neisseria
meningitidis MC58]
Length = 637
Score = 165 bits (414), Expect = 5e-40
Identities = 106/312 (33%), Positives = 163/312 (51%), Gaps = 13/312 (4%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
++ + FG+ L + + ++ + ++ + V FE +FPDR+ VGI+EQ + A G
Sbjct: 331 TYTQVFGKWLCDRAAADSRLVAITPAMREGSGLVEFEQRFPDRYFDVGIAEQHAVTFAGG 390
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P+V+ ++ FL RA++Q+ + IA NL V +G DG +H L D++
Sbjct: 391 LACEGMKPVVAIYSTFLQRAYDQLVHDIALQNLPVLFAVDRAGIVG-ADGPTHAGLYDLS 449
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRL--GRDFAPRVYEDGDEIKLGKAN 181
+R +PNM V P+D R LL + PA +R G V + + +++GK
Sbjct: 450 FLRCVPNMIVAAPSDENECRLLLSTCYQADAPAAVRYPRGTGTGAPVSDGMETVEIGKGI 509
Query: 182 ILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLV 241
I R+G F+A G MV+ AL VAE L +A V DM VKP+DE ++ LAR + +
Sbjct: 510 IRREGEKTAFIAFGSMVAPALAVAEKL-----NATVADMRFVKPIDEELIVRLARSHDRI 564
Query: 242 ITLEEHTIFGGLGGAVAEALSEK---MPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKV 298
+TLEE+ GG GGAV E L++ P ++ + T G D LLD GLS V
Sbjct: 565 VTLEENAEQGGAGGAVLEVLAKHGICKPVLLLGVADTVTGHG--DPKKLLDDLGLSAEAV 622
Query: 299 YSKVLEVVKNED 310
+V + + D
Sbjct: 623 ERRVRAWLSDRD 634
>pir||T20473 hypothetical protein F01G10.1 - Caenorhabditis elegans
>gi|3875549|emb|CAB02889.1| (Z81055) predicted using
Genefinder~Similarity to Human transketolase
(SW:TKT_HUMAN), contains similarity to Pfam domain:
PF00456 (Transketolase), Score=557.7, E-value=2.4e-164,
N=2~cDNA EST cm01f8 comes from this gene~cDNA EST
EMBL:M75846 comes from t>
Length = 618
Score = 165 bits (413), Expect = 7e-40
Identities = 106/301 (35%), Positives = 161/301 (53%), Gaps = 6/301 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R ++G L ++G + VI +D D KNST + + PD+FI+ I+EQ+++G A G
Sbjct: 316 RAAYGTALAKLGDASPRVIGLDGDTKNSTFSDKLLKKHPDQFIECFIAEQNLVGVAVGAQ 375
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ IP S FAAF RA +QIR A N+K V +H G S DG S LED+A+
Sbjct: 376 CRDRTIPFTSTFAAFFTRATDQIRMA-AVSFANLKCVGSHVGVSIGEDGPSQMALEDLAI 434
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P DA + G ++R GR P +Y++ + +G+A +++
Sbjct: 435 FRTIPGATVFYPTDAVSAERATELAANTKGVVFIRTGRPALPVLYDNEEPFHIGQAKVVK 494
Query: 185 DGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
+ I+ V SGV + +L+ AE L+ GI A V+D T+KPLD +T+ A KV V
Sbjct: 495 QSAQDKIVLVGSGVTLYESLKAAEELEKEGIHATVIDPFTIKPLDGKTIAEHALKVGGRV 554
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
+T E+H GG+G AV+ AL++ RV + RS +L+D YG+S + +
Sbjct: 555 VTTEDHYAAGGIGEAVSAALADYPTIRVRSLNVKEVPRSGPPD-ALVDMYGISARHIVAA 613
Query: 302 V 302
V
Sbjct: 614 V 614
>pir||B81978 probable 1-deoxyxylulose-5-phosphate synthase NMA0589 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7379325|emb|CAB83880.1| (AL162753) putative
1-deoxyxylulose-5-phosphate synthase [Neisseria
meningitidis Z2491]
Length = 637
Score = 162 bits (405), Expect = 6e-39
Identities = 107/312 (34%), Positives = 162/312 (51%), Gaps = 13/312 (4%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
++ + FG+ L + + ++ + ++ + V FE +FPDR+ VGI+EQ + A G
Sbjct: 331 TYTQVFGKWLCDRAAADSRLVAITPAMREGSGLVEFEQRFPDRYFDVGIAEQHAVTFAGG 390
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P+V+ ++ FL RA++Q+ + IA NL V +G DG +H L D++
Sbjct: 391 LACEGMKPVVAIYSTFLQRAYDQLVHDIALQNLPVLFAVDRAGIVG-ADGPTHAGLYDLS 449
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRV-YEDGDE-IKLGKAN 181
+R +PNM V P+D R LL + PA +R R V DG E +++GK
Sbjct: 450 FLRCIPNMIVAAPSDENECRLLLSTCYQADAPAAVRYPRGTGTGVPVSDGMETVEIGKGI 509
Query: 182 ILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLV 241
I R+G F+A G MV+ AL VA L +A V DM VKP+DE ++ LAR + +
Sbjct: 510 IRREGEKTAFIAFGSMVAPALAVAGKL-----NATVADMRFVKPIDEELIVRLARSHDRI 564
Query: 242 ITLEEHTIFGGLGGAVAEALSEK---MPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKV 298
+TLEE+ GG G AV E L++ P ++ + T G D LLD GLS V
Sbjct: 565 VTLEENAEQGGAGSAVLEVLAKHGICKPVLLLGVADTVTGHG--DPKKLLDDLGLSAEAV 622
Query: 299 YSKVLEVVKNED 310
+V + + D
Sbjct: 623 ERRVRAWLSDRD 634
>gb|AAF76194.1| (AF270484) transketolase [Xenopus laevis]
Length = 625
Score = 160 bits (401), Expect = 2e-38
Identities = 99/308 (32%), Positives = 163/308 (52%), Gaps = 8/308 (2%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R+++G L ++G N VI +D D KNST + F+ + PDR+I+ I+EQ+M+ A G A
Sbjct: 321 RKAYGLALAKLGHANSRVIALDGDTKNSTFSDIFKKEHPDRYIECFIAEQNMVSVAMGCA 380
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIR-NTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
G+ + S FAAFL RA++ IR I++ N+N + +H G S DG S LED++
Sbjct: 381 TRGRTVAFASTFAAFLSRAYDHIRMGAISQSNVN--LCGSHCGVSIGEDGPSQMALEDLS 438
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANIL 183
+ R +P V P+D +T ++ G ++R R +Y ++ ++G+A ++
Sbjct: 439 MFRAIPTCTVFYPSDGVSTEHAVFLSANTPGICFIRTSRPDTAVIYSPEEKFEIGQAKVV 498
Query: 184 RDGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NL 240
R S + + +GV + AL A+ L GI+ V+D T+KPLD T+++ R
Sbjct: 499 RQSSSDRVTVIGAGVTLHEALAAADELAKQGINIRVIDPFTIKPLDAATILSSGRATGGH 558
Query: 241 VITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYS 300
+IT+E+H GG+G AV A++ + V + RS + LLD +G+S +
Sbjct: 559 IITVEDHYREGGIGEAVCAAVAGEPGFIVQTLAVRGVPRSGKP-TELLDMFGISARCIVE 617
Query: 301 KVLEVVKN 308
V N
Sbjct: 618 AVKTTFAN 625
>gi|6678359 transketolase [Mus musculus] >gi|730956|sp|P40142|TKT_MOUSE
TRANSKETOLASE (TK) (P68) >gi|452486|gb|AAC52443.1|
(U05809) transketolase [Mus musculus]
Length = 623
Score = 160 bits (400), Expect = 2e-38
Identities = 97/305 (31%), Positives = 163/305 (52%), Gaps = 6/305 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R+++G L ++G + +I +D D KNST + F+ + PDRFI+ I+EQ+M+ A G A
Sbjct: 318 RKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPDRFIECYIAEQNMVSIAVGCA 377
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ +P S FAAF RA++QIR ++ N+ + +H G S DG S LED+A+
Sbjct: 378 TRDRTVPFCSTFAAFFTRAFDQIRMAAISES-NINLCGSHCGVSIGEDGPSQMALEDLAM 436
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P+D AT + G ++R R +Y + ++ ++G+A ++
Sbjct: 437 FRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVL 496
Query: 185 DGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
D + + +GV + AL AE+LK I VLD T+KPLD + +++ AR +
Sbjct: 497 KSKDDQVTVIGAGVTLHEALAAAESLKKDKISIRVLDPFTIKPLDRKLILDSARATKGRI 556
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
+T+E+H GG+G AV+ A+ + V R+ + RS + LL +G+ + +
Sbjct: 557 LTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPRSGKP-AELLKMFGIDKDAIVQA 615
Query: 302 VLEVV 306
V +V
Sbjct: 616 VKGLV 620
>gb|AAG28459.1|AF195533_1 (AF195533) transketolase [Mus musculus]
Length = 559
Score = 160 bits (400), Expect = 2e-38
Identities = 97/305 (31%), Positives = 163/305 (52%), Gaps = 6/305 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R+++G L ++G + +I +D D KNST + F+ + PDRFI+ I+EQ+M+ A G A
Sbjct: 254 RKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPDRFIECYIAEQNMVSIAVGCA 313
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ +P S FAAF RA++QIR ++ N+ + +H G S DG S LED+A+
Sbjct: 314 TRDRTVPFCSTFAAFFTRAFDQIRMAAISES-NINLCGSHCGVSIGEDGPSQMALEDLAM 372
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P+D AT + G ++R R +Y + ++ ++G+A ++
Sbjct: 373 FRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVL 432
Query: 185 DGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
D + + +GV + AL AE+LK I VLD T+KPLD + +++ AR +
Sbjct: 433 KSKDDQVTVIGAGVTLHEALAAAESLKKDKISIRVLDPFTIKPLDRKLILDSARATKGRI 492
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
+T+E+H GG+G AV+ A+ + V R+ + RS + LL +G+ + +
Sbjct: 493 LTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPRSGKP-AELLKMFGIDKDAIVQA 551
Query: 302 VLEVV 306
V +V
Sbjct: 552 VKGLV 556
>pir||A45050 transketolase (EC 2.2.1.1) - human >gi|37267|emb|CAA47919.1|
(X67688) transketolase [Homo sapiens]
Length = 623
Score = 159 bits (398), Expect = 4e-38
Identities = 95/301 (31%), Positives = 161/301 (52%), Gaps = 6/301 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R+++G+ L ++G + +I +D D KNST + F+ + PDRFI+ I+EQ+M+ A G A
Sbjct: 318 RKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCA 377
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ +P S FAAF RA++QIR ++ N+ + +H G S DG+S LED+A+
Sbjct: 378 TRNRTVPFCSTFAAFFTRAFDQIRMAAISES-NINLCGSHCGVSIGEDGASQMALEDLAM 436
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P+D AT + G ++R R +Y + ++ ++G+A ++
Sbjct: 437 FRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVL 496
Query: 185 DGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
D + + +GV + AL AE LK I+ VLD T+KPLD + +++ AR +
Sbjct: 497 KSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRI 556
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
+T+E+H GG+G AV+ A+ + V + RS + LL +G+ + +
Sbjct: 557 LTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKP-AELLKMFGIDRDAIAQA 615
Query: 302 V 302
V
Sbjct: 616 V 616
>gi|4507521 transketolase (Wernicke-Korsakoff syndrome) [Homo sapiens]
>gi|11434224|ref|XP_003107.1| transketolase
(Wernicke-Korsakoff syndrome) [Homo sapiens]
>gi|1729976|sp|P29401|TKT_HUMAN TRANSKETOLASE (TK)
>gi|1297297|gb|AAA98961.1| (U55017) transketolase [Homo
sapiens]
Length = 623
Score = 158 bits (396), Expect = 7e-38
Identities = 95/301 (31%), Positives = 160/301 (52%), Gaps = 6/301 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R+++G+ L ++G + +I +D D KNST + F+ + PDRFI+ I+EQ+M+ A G A
Sbjct: 318 RKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCA 377
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ +P S FAAF RA++QIR ++ N+ + +H G S DG S LED+A+
Sbjct: 378 TRNRTVPFCSTFAAFFTRAFDQIRMAAISES-NINLCGSHCGVSIGEDGPSQMALEDLAM 436
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P+D AT + G ++R R +Y + ++ ++G+A ++
Sbjct: 437 FRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVL 496
Query: 185 DGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
D + + +GV + AL AE LK I+ VLD T+KPLD + +++ AR +
Sbjct: 497 KSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRI 556
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
+T+E+H GG+G AV+ A+ + V + RS + LL +G+ + +
Sbjct: 557 LTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKP-AELLKMFGIDRDAIAQA 615
Query: 302 V 302
V
Sbjct: 616 V 616
>sp|P50137|TKT_RAT TRANSKETOLASE (TK)
Length = 623
Score = 158 bits (396), Expect = 7e-38
Identities = 96/305 (31%), Positives = 162/305 (52%), Gaps = 6/305 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R+++G L ++G + +I +D D KNST + F+ + PDRFI+ I+EQ+M+ A G A
Sbjct: 318 RKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPDRFIECYIAEQNMVSIAVGCA 377
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ +P S FAAF RA++QIR ++ N+ + +H G S DG S LED+A+
Sbjct: 378 TRDRTVPFCSTFAAFFTRAFDQIRMAAISES-NINLCGSHCGVSIGEDGPSQMALEDLAM 436
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P+D AT + G ++R R +Y + ++ ++G+A ++
Sbjct: 437 FRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVL 496
Query: 185 DGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
D + + +GV + AL AE LK I VLD T+KPLD++ +++ AR +
Sbjct: 497 KSKDDQVTVIGAGVTLHEALAAAEMLKKEKIGVRVLDPFTIKPLDKKLILDCARATKGRI 556
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
+T+E+H GG+G AV+ + + V R+ + RS + LL +G+ + +
Sbjct: 557 LTVEDHYYEGGIGEAVSAVVVGEPGVTVTRLAVSQVPRSGKP-AELLKMFGIDKDAIVQA 615
Query: 302 VLEVV 306
V +V
Sbjct: 616 VKGLV 620
>gb|AAA18026.1| (U09256) transketolase [Rattus norvegicus]
Length = 655
Score = 158 bits (396), Expect = 7e-38
Identities = 96/305 (31%), Positives = 162/305 (52%), Gaps = 6/305 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R+++G L ++G + +I +D D KNST + F+ + PDRFI+ I+EQ+M+ A G A
Sbjct: 350 RKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPDRFIECYIAEQNMVSIAVGCA 409
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ +P S FAAF RA++QIR ++ N+ + +H G S DG S LED+A+
Sbjct: 410 TRDRTVPFCSTFAAFFTRAFDQIRMAAISES-NINLCGSHCGVSIGEDGPSQMALEDLAM 468
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P+D AT + G ++R R +Y + ++ ++G+A ++
Sbjct: 469 FRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVL 528
Query: 185 DGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
D + + +GV + AL AE LK I VLD T+KPLD++ +++ AR +
Sbjct: 529 KSKDDQVTVIGAGVTLHEALAAAEMLKKEKIGVRVLDPFTIKPLDKKLILDCARATKGRI 588
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
+T+E+H GG+G AV+ + + V R+ + RS + LL +G+ + +
Sbjct: 589 LTVEDHYYEGGIGEAVSAVVVGEPGVTVTRLAVSQVPRSGKP-AELLKMFGIDKDAIVQA 647
Query: 302 VLEVV 306
V +V
Sbjct: 648 VKGLV 652
>pir||PH0845 transketolase (EC 2.2.1.1) - human (fragment)
Length = 392
Score = 158 bits (396), Expect = 7e-38
Identities = 94/293 (32%), Positives = 158/293 (53%), Gaps = 6/293 (2%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R+++G+ L ++G + +I +D D KNST + F+ + PDRFI+ I+EQ+M+ A G A
Sbjct: 95 RKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCA 154
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ +P S FAAF RA++QIR ++ N+ + +H G S DG S LED+A+
Sbjct: 155 TRNRTVPFCSTFAAFFTRAFDQIRMAAISES-NINLCGSHCGVSIGEDGPSQMALEDLAM 213
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P+D AT + G ++R R +Y + ++ ++G+A ++
Sbjct: 214 FRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVL 273
Query: 185 DGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
D + + +GV + AL AE LK I+ VLD T+KPLD + +++ AR +
Sbjct: 274 KSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRI 333
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLS 294
+T+E+H GG+G AV+ A+ + V + RS + LL +G++
Sbjct: 334 LTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKP-AELLKMFGIT 385
>gb|AAA61222.1| (L12711) transketolase [Homo sapiens]
Length = 623
Score = 157 bits (393), Expect = 2e-37
Identities = 88/260 (33%), Positives = 146/260 (55%), Gaps = 5/260 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R+++G+ L ++G + +I +D D KNST + F+ + PDRFI+ I+EQ+M+ A G A
Sbjct: 318 RKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCA 377
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ +P S FAAF RA++QIR ++ N+ + +H G S DG S LED+A+
Sbjct: 378 TRNRTVPFCSTFAAFFTRAFDQIRMAAISES-NINLCGSHCGVSIGEDGPSQMALEDLAM 436
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P+D AT + G ++R R +Y + ++ ++G+A ++
Sbjct: 437 FRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVL 496
Query: 185 DGSD--ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
D + + +GV + AL AE LK I+ VLD T+KPLD + +++ AR +
Sbjct: 497 KSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRI 556
Query: 242 ITLEEHTIFGGLGGAVAEAL 261
+T+E+H GG+G AV+ A+
Sbjct: 557 LTVEDHYYEGGIGEAVSSAV 576
>sp|O67036|DXS_AQUAE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
>gi|7446977|pir||A70376 conserved hypothetical protein
aq_881 - Aquifex aeolicus >gi|2983421|gb|AAC07004.1|
(AE000712) hypothetical protein [Aquifex aeolicus]
Length = 628
Score = 157 bits (393), Expect = 2e-37
Identities = 94/267 (35%), Positives = 147/267 (54%), Gaps = 3/267 (1%)
Query: 9 FGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAG 68
FG+ LVE+ +++ ++ + ++ + V F +FPDRF VGI+EQ AAGLA G
Sbjct: 324 FGKALVELAERDEKIVAITPAMREGSGLVEFAKRFPDRFFDVGIAEQHACTFAAGLAAEG 383
Query: 69 KIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVL 128
P+ + ++ FL RA++Q+ + +A NL V +G DG +H + D++ +R +
Sbjct: 384 LRPVAAYYSTFLQRAYDQVIHDVALQNLPVTFAIDRAGLVGD-DGPTHHGVFDLSYLRCV 442
Query: 129 PNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDG-DEIKLGKANILRDGS 187
PNM V P D R LLY + P +R R A V +G +I++G L +G
Sbjct: 443 PNMVVCAPKDEQELRDLLYTGIYSGKPFALRYPRGAAYGVPTEGFKKIEIGTWEELLEGE 502
Query: 188 DILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEH 247
D + +A G V AL AE L GI GV++ VKP+DE+ L +LA + + IT+E++
Sbjct: 503 DCVILAVGYPVYQALRAAEKLYKEGIRVGVVNARFVKPMDEKMLRDLANRYDTFITVEDN 562
Query: 248 TIFGGLGGAVAEALS-EKMPRRVIRIG 273
T+ GG G V E + E + +RVI +G
Sbjct: 563 TVVGGFGSGVLEFFAREGIMKRVINLG 589
>emb|CAB60078.1| (Y18874) 1-deoxy-xylulose 5-phosphate synthase [Synechococcus
PCC6301]
Length = 636
Score = 157 bits (392), Expect = 2e-37
Identities = 90/261 (34%), Positives = 143/261 (54%), Gaps = 4/261 (1%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ + FG+TL + + ++ ++ + A + T + P ++I VGI+EQ + AAG
Sbjct: 320 SYSKVFGQTLTTLAKSDRRIVGITAAMATGTGLDILQKALPKQYIDVGIAEQHAVVLAAG 379
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
+A G P+V+ ++ FL RA++Q+ + + L V +G DG +HQ + DIA
Sbjct: 380 MACDGMRPVVAIYSTFLQRAFDQVIHDVCIQKLPVFFCLDRAGIVG-ADGPTHQGMYDIA 438
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFA---PRVYEDGDEIKLGKA 180
+R++PNM ++ P D + +L +E GP MR R P E + + +GKA
Sbjct: 439 YLRLIPNMVLMAPKDEAELQRMLVTGIEYDGPIAMRFPRGNGIGVPLPEEGWESLPIGKA 498
Query: 181 NILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNL 240
LR G D+L +A G MV AL+ AE L GI A V++ KPLDE ++ LAR++
Sbjct: 499 EQLRQGDDLLMLAYGSMVYPALQTAELLNEHGISATVINARFAKPLDEELIVPLARQIGK 558
Query: 241 VITLEEHTIFGGLGGAVAEAL 261
V+T EE + GG G A+ E+L
Sbjct: 559 VVTFEEGCLPGGFGSAIMESL 579
>gb|AAF54265.1| (AE003680) CG8036 gene product [Drosophila melanogaster]
Length = 626
Score = 153 bits (384), Expect = 2e-36
Identities = 100/307 (32%), Positives = 161/307 (51%), Gaps = 6/307 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R ++G L +IG+ N V+ +D D KNST + +N P R+I+ I+EQ+++G A G A
Sbjct: 322 RLAYGTALAKIGQNNLRVVALDGDTKNSTFSDKLKNLDPQRYIECFIAEQNLVGVAVGAA 381
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ + VS FA F RA++QIR A NV V +H G S DG S LEDIA+
Sbjct: 382 CRRRTVAFVSTFATFFTRAFDQIRMG-AISQTNVNFVGSHCGCSIGEDGPSQMGLEDIAM 440
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P + P+DA +T + G ++R R +Y++ + +G+ ++R
Sbjct: 441 FRTIPGSTIFYPSDAVSTERAVELAANTKGVCFIRTSRPNTCVIYDNEEPFTIGRGKVVR 500
Query: 185 DGS--DILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
S ++L + +G+ + L A+ L+ I V+D TVKPLD +I ++ V
Sbjct: 501 QKSSDEVLLIGAGITLYECLAAADQLEKNCITVRVIDPFTVKPLDAELIIEHGKQCGGRV 560
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
+ +E+H GGLG AV AL+ + V + T RS + L+D +G+S V +
Sbjct: 561 VVVEDHYQQGGLGEAVLSALAGERNFVVKHLYVPTVPRSGPPSV-LIDMFGISARHVVNA 619
Query: 302 VLEVVKN 308
V E++K+
Sbjct: 620 VNEILKD 626
>dbj|BAB06498.1| (AP001516) 1-deoxyxylulose-5-phosphate synthase [Bacillus
halodurans]
Length = 629
Score = 153 bits (382), Expect = 3e-36
Identities = 95/308 (30%), Positives = 160/308 (51%), Gaps = 6/308 (1%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ F TL +I R + ++ + A + TK F +FPDR VGI+EQ A G
Sbjct: 316 SYSGVFAETLKKIARNDPRIVALTAAMPGGTKLDQFAKEFPDRMFDVGIAEQHATTMAGG 375
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P+ + ++ FL R ++Q+ + I R NLNV +G DG +HQ + DIA
Sbjct: 376 LATQGLKPVFAVYSTFLQRGYDQVVHDICRQNLNVFFAIDRAGLVG-ADGETHQGVFDIA 434
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVE-DHGPAYMRL--GRDFAPRVYEDGDEIKLGKA 180
+R LPNMK+++P D + ++Y ++ + GP +R G + ++ E EI +G
Sbjct: 435 YLRHLPNMKILMPKDENELQHMVYTAIQYEGGPIAVRYPRGNGYGIKMDEVLKEIPIGSW 494
Query: 181 NILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNL 240
+L++G+D + G M+ VA + ++ L G +++ +VKPLDE L +A+
Sbjct: 495 EVLQEGTDACILTFGTMIPVAEQASKELSQQGYSIRLINARSVKPLDEAMLHEIAKSGRP 554
Query: 241 VITLEEHTIFGGLGGAVAEALSEKMPRRVI--RIGSTTFGRSSRDYLSLLDRYGLSVNKV 298
V+TLEE + G G AV E + V+ R+G LL+ GL+ ++V
Sbjct: 555 VLTLEETAVQGSFGSAVLEFFHDHGYHNVVTQRMGIPDRFIEHGSVSELLEEIGLTSSQV 614
Query: 299 YSKVLEVV 306
+++ +++
Sbjct: 615 ANQLSKLL 622
>sp|P73067|DXS_SYNY3 PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
>gi|7446979|pir||S75175 hypothetical protein sll1945 -
Synechocystis sp. (strain PCC 6803)
>gi|1652165|dbj|BAA17089.1| (D90903) hypothetical
protein [Synechocystis sp.]
Length = 640
Score = 152 bits (380), Expect = 5e-36
Identities = 89/264 (33%), Positives = 144/264 (53%), Gaps = 5/264 (1%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ + F TL + ++N +++ + A + T + + P +++ VGI+EQ + AAG
Sbjct: 320 SYSKVFAHTLTTLAKENPNIVGITAAMATGTGLDKLQAKLPKQYVDVGIAEQHAVTLAAG 379
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
+A G P+V+ ++ FL R ++QI + + L V +G DG +HQ + DIA
Sbjct: 380 MACEGIRPVVAIYSTFLQRGYDQIIHDVCIQKLPVFFCLDRAGIVG-ADGPTHQGMYDIA 438
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPA----YMRLGRDFAPRVYEDGDEIKLGK 179
+R +PN+ ++ P D + +L V G A Y R P + E + +++GK
Sbjct: 439 YLRCIPNLVLMAPKDEAELQQMLVTGVNYTGGAIAMRYPRGNGIGVPLMEEGWEPLEIGK 498
Query: 180 ANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVN 239
A ILR G D+L + G MV AL+ AE L GI+A V++ VKPLD ++ LA ++
Sbjct: 499 AEILRSGDDVLLLGYGSMVYPALQTAELLHEHGIEATVVNARFVKPLDTELILPLAERIG 558
Query: 240 LVITLEEHTIFGGLGGAVAEALSE 263
V+T+EE + GG G AVAEAL +
Sbjct: 559 KVVTMEEGCLMGGFGSAVAEALMD 582
>pir||G75390 1-deoxy-D-xylulose-5-phosphate synthase - Deinococcus radiodurans
(strain R1) >gi|6459235|gb|AAF11042.1|AE001992_2
(AE001992) 1-deoxy-D-xylulose-5-phosphate synthase
[Deinococcus radiodurans]
Length = 629
Score = 147 bits (368), Expect = 1e-34
Identities = 85/270 (31%), Positives = 148/270 (54%), Gaps = 6/270 (2%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ +FG + E + + VV ++ + V F P R++ VGI+E+ + TAAG
Sbjct: 323 SWSAAFGEAVTEWAKTDPRTFVVTPAMREGSGLVEFSRVHPHRYLDVGIAEEVAVTTAAG 382
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
+A+ G P+V+ ++ FL RA++Q+ + +A ++LNV +G DG++H + D++
Sbjct: 383 MALQGMRPVVAIYSTFLQRAYDQVLHDVAIEHLNVTFCIDRAGIVG-ADGATHNGVFDLS 441
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRV-YEDGDEIKLGKANI 182
+R +P +++ +P DA R +L GP +R R +V ++K G+
Sbjct: 442 FLRSIPGVRIGLPKDAAELRGMLKYAQTHDGPFAIRYPRGNTAQVPAGTWPDLKWGEWER 501
Query: 183 LRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
L+ G D++ +A G + AL+ AE+L GV GV++ VKPLDE L + + +I
Sbjct: 502 LKGGDDVVILAGGKALDYALKAAEDLPGV----GVVNARFVKPLDEEMLREVGGRARALI 557
Query: 243 TLEEHTIFGGLGGAVAEALSEKMPRRVIRI 272
T+E++T+ GG GGAV EAL+ +R+
Sbjct: 558 TVEDNTVVGGFGGAVLEALNSMNLHPTVRV 587
>gi|7110727 transketolase-like 1; Transketolase-2 [Homo sapiens]
>gi|11419900|ref|XP_010159.1| transketolase-like 1 [Homo
sapiens] >gi|1729975|sp|P51854|TKT2_HUMAN TRANSKETOLASE
2 (TK 2) (TRANSKETOLASE RELATED PROTEIN)
>gi|1232175|emb|CAA62925.1| (X91817) transketolase [Homo
sapiens] >gi|1588307|prf||2208324A transketolase [Homo
sapiens]
Length = 557
Score = 146 bits (365), Expect = 3e-34
Identities = 98/315 (31%), Positives = 161/315 (51%), Gaps = 25/315 (7%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R++ G L ++G N V+V+D D + ST + F ++P+RFI+ ++EQ+M+ A G A
Sbjct: 236 RKACGLALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCA 295
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIR-NTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
G+ I S FAAFL RA++ IR +A N+N I+ +H G S DG+S LEDIA
Sbjct: 296 SRGRTIAFASTFAAFLTRAFDHIRIGGLAESNIN--IIGSHCGVSVGDDGASQMALEDIA 353
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKA--- 180
+ R +P + P DA +T + G ++R R +Y + ++G+A
Sbjct: 354 MFRTIPKCTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKGV 413
Query: 181 NILRD----------------GSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVK 224
++L+D + + +G+ V AL A+ L I V+D+ T+K
Sbjct: 414 SMLQDSWSSVISYQKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIK 473
Query: 225 PLDERTLINLARKV-NLVITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRD 283
PLD T+++ A+ +IT+E+H GG+G AV A+S +V + + +S +
Sbjct: 474 PLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKS 533
Query: 284 YLSLLDRYGLSVNKV 298
LLD YG+S +
Sbjct: 534 E-ELLDMYGISARHI 547
>gb|AAF49267.1| (AE003521) CG5103 gene product [Drosophila melanogaster]
Length = 623
Score = 146 bits (364), Expect = 4e-34
Identities = 98/306 (32%), Positives = 151/306 (49%), Gaps = 6/306 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R ++G L +I N VI +D D KNST N FP+RFI+ ++Q+++G A G
Sbjct: 319 RLAYGTALAKIAADNPRVIALDGDTKNSTYADKMRNAFPERFIECFTAQQNLVGVAVGAT 378
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ + VS +A F RA++QIR A + NV +H G S DG S LED+A+
Sbjct: 379 CRRRTVAFVSTYATFFTRAFDQIRMG-AISHTNVNFAGSHCGCSIGEDGPSQMGLEDMAM 437
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
R +P V P DA +T + G Y+R +Y + + +G ++R
Sbjct: 438 FRSIPGSTVFYPTDAVSTERAVELAANTKGVCYIRTTYPSTTVIYNNDEVFAVGLGKVVR 497
Query: 185 D--GSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV-NLV 241
++L + +GV + L AE L+ I A V+D TVKPLD ++ + +
Sbjct: 498 QKPSDEVLLIGAGVTLYECLAAAERLEEDCITARVIDPFTVKPLDVGLIVKHGKLCRGRI 557
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
+ +E+H GGLG AV AL++ V + TT RS + LLD +G+S +Y
Sbjct: 558 VVVEDHYQQGGLGEAVLSALADYRNFVVKHLYITTVPRSGPPAV-LLDMFGVSSRNIYKA 616
Query: 302 VLEVVK 307
L ++K
Sbjct: 617 SLAIMK 622
>sp|P45205|DXS_HAEIN 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
>gi|1074781|pir||B64172 dxs protein - Haemophilus
influenzae (strain Rd KW20) >gi|1574278|gb|AAC23088.1|
(U32822) 1-deoxyxylulose-5-phosphate synthase (dxs)
{Escherichia coli) [Haemophilus influenzae Rd]
Length = 625
Score = 145 bits (363), Expect = 5e-34
Identities = 95/308 (30%), Positives = 159/308 (50%), Gaps = 8/308 (2%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
++ + FG L E+ K+ +I + ++ + V F +FP ++ V I+EQ + A G
Sbjct: 321 TYSKIFGDWLCEMAEKDAKIIGITPAMREGSGMVEFSQRFPKQYFDVAIAEQHAVTFATG 380
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LAI G P+V+ ++ FL RA++Q+ + +A NL V +G DG++HQ DI+
Sbjct: 381 LAIGGYKPVVAIYSTFLQRAYDQLIHDVAIQNLPVLFAIDRAGIVG-ADGATHQGAFDIS 439
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRV-YEDGDEIKLGKANI 182
MR +PNM ++ P+D R +LY + PA +R R A V + + +GK+ +
Sbjct: 440 FMRCIPNMIIMTPSDENECRQMLYTGYQCGKPAAVRYPRGNAVGVKLTPLEMLPIGKSRL 499
Query: 183 LRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
+R G I + G ++ ALE++E L +A V+DM VKP+D + LA+ + ++
Sbjct: 500 IRKGQKIAILNFGTLLPSALELSEKL-----NATVVDMRFVKPIDIEMINVLAQTHDYLV 554
Query: 243 TLEEHTIFGGLGGAVAEAL-SEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYSK 301
TLEE+ I GG G AVAE L S ++++G + L GL + K
Sbjct: 555 TLEENAIQGGAGSAVAEVLNSSGKSTALLQLGLPDYFIPQATQQEALADLGLDTKGIEEK 614
Query: 302 VLEVVKNE 309
+L + +
Sbjct: 615 ILNFIAKQ 622
>dbj|BAA74730.1| (AB016786) transketolase [Ascidia sydneiensis samea]
Length = 624
Score = 142 bits (354), Expect = 6e-33
Identities = 86/261 (32%), Positives = 140/261 (52%), Gaps = 4/261 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R +G+ L++IG++ V +D D+KNST ++ FPD FI+ I+EQ+M+G G+A
Sbjct: 323 RAGYGKALIKIGQRCDRVYSLDGDMKNSTFAQDYKKAFPDHFIECFIAEQNMVGVGIGMA 382
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIAL 124
+ + +S FAAF+ RA++ IR A + N+ I +H G S DG S LED+A+
Sbjct: 383 TRDRTVVFLSTFAAFMARAYDHIRMG-AVCHTNINIFGSHCGISIGADGPSQMALEDLAM 441
Query: 125 MRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANIL- 183
R + V P+D + + G ++R R P VY+ + ++G+ IL
Sbjct: 442 FRAVQGSTVFYPSDVVSVERAVELSANTKGICFIRGARAATPVVYDKDTKFEVGRCQILK 501
Query: 184 -RDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
+ G + VA G+ + AL+ + L+ GI ++D+ +VKP+D+ + A +
Sbjct: 502 QKSGDKVTIVAGGITFAEALKAFDKLQTDGIGVTLIDIFSVKPVDKDGIYQAAWQPGKDP 561
Query: 243 TLEEHTIFGGLGGAVAEALSE 263
+H GG+G AVAEALSE
Sbjct: 562 HGGDHYEEGGIGSAVAEALSE 582
>sp|P77488|DXS_ECOLI 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
>gi|7446978|pir||D64771 dxs protein - Escherichia coli
>gi|1773104|gb|AAB40176.1| (U82664) similar to H.
influenzae HI1439 [Escherichia coli]
>gi|1786622|gb|AAC73523.1| (AE000148)
1-deoxyxylulose-5-phosphate synthase; flavoprotein
[Escherichia coli K12] >gi|2665586|gb|AAC46162.1|
(AF035440) D-1-deoxyxylulose 5-phosphate synthase
[Escherichia coli]
Length = 620
Score = 141 bits (353), Expect = 8e-33
Identities = 89/279 (31%), Positives = 148/279 (52%), Gaps = 9/279 (3%)
Query: 2 IESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTA 61
+ S+ + FG L E K+ ++ + ++ + V F +FPDR+ V I+EQ + A
Sbjct: 318 LPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFA 377
Query: 62 AGLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLED 121
AGLAI G PIV+ ++ FL RA++Q+ + +A L V +G DG +HQ D
Sbjct: 378 AGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVG-ADGQTHQGAFD 436
Query: 122 IALMRVLPNMKVVVPADAYATRALLYEIVE-DHGPAYMRLGRDFAPRV-YEDGDEIKLGK 179
++ +R +P M ++ P+D R +LY + GP+ +R R A V +++ +GK
Sbjct: 437 LSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGK 496
Query: 180 ANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVN 239
+ R G + + G ++ A +VAE+L +A ++DM VKPLDE ++ +A
Sbjct: 497 GIVKRRGEKLAILNFGTLMPEAAKVAESL-----NATLVDMRFVKPLDEALILEMAASHE 551
Query: 240 LVITLEEHTIFGGLGGAVAEAL-SEKMPRRVIRIGSTTF 277
++T+EE+ I GG G V E L + + P V+ IG F
Sbjct: 552 ALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDF 590
>pir||H82266 1-deoxyxylulose-5-phosphate synthase VC0889 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9655344|gb|AAF94051.1| (AE004173)
1-deoxyxylulose-5-phosphate synthase [Vibrio cholerae]
Length = 626
Score = 141 bits (352), Expect = 1e-32
Identities = 86/278 (30%), Positives = 148/278 (52%), Gaps = 14/278 (5%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
+F + FG L ++ ++ ++ + ++ + V F ++P ++ V I+EQ + A G
Sbjct: 320 TFSKIFGDFLCDMAAQDPKLMAITPAMREGSGMVRFSKEYPSQYFDVAIAEQHAVTLATG 379
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
+AIAG PIV+ ++ FL R ++Q+ + +A NL V +G DG +HQ D++
Sbjct: 380 MAIAGYHPIVAIYSTFLQRGYDQLIHDVAIMNLPVMFAIDRAGIVG-ADGQTHQGAFDLS 438
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRL--GRDFAPRVYEDGDEIKLGKAN 181
MR +PNM ++ PAD R +LY + GP+ +R G + +++GK
Sbjct: 439 YMRCIPNMLIMAPADENECRQMLYTGHQHQGPSAVRYPRGNGMGVELESSFTALEIGKGR 498
Query: 182 ILR-----DGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLAR 236
++R +G + ++ G ++ AL+ AE L +A V DM VKPLDE + LA+
Sbjct: 499 LMRESTACEGEKVAILSFGTLLPNALQAAEKL-----NATVADMRFVKPLDEALIKQLAQ 553
Query: 237 KVNLVITLEEHTIFGGLGGAVAEAL-SEKMPRRVIRIG 273
++++TLEE+ I GG G V E L EK + V+ +G
Sbjct: 554 THDVLVTLEENAIAGGAGAGVIEFLMKEKQLKPVLNLG 591
>sp|P54523|DXS_BACSU PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
>gi|7446982|pir||B69961 conserved hypothetical protein
yqiE - Bacillus subtilis >gi|1303920|dbj|BAA12576.1|
(D84432) YqiE [Bacillus subtilis]
>gi|2634861|emb|CAB14358.1| (Z99116) similar to
hypothetical proteins [Bacillus subtilis]
Length = 633
Score = 141 bits (351), Expect = 1e-32
Identities = 87/305 (28%), Positives = 158/305 (51%), Gaps = 24/305 (7%)
Query: 12 TLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAGKIP 71
T+ + R++ ++ + + +K F +FPDR VGI+EQ AA +A+ G P
Sbjct: 325 TVQRMAREDGRIVAITPAMPVGSKLEGFAKEFPDRMFDVGIAEQHAATMAAAMAMQGMKP 384
Query: 72 IVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNM 131
++ ++ FL RA++Q+ + I R N NV I +G DG +HQ + DIA MR +PNM
Sbjct: 385 FLAIYSTFLQRAYDQVVHDICRQNANVFIGIDRAGLVG-ADGETHQGVFDIAFMRHIPNM 443
Query: 132 KVVVPADAYATRALLYEIVE-DHGPAYMRL--GRDFAPRVYEDGDEIKLGKANILRDGSD 188
+++P D + +++ + D GP MR G ++ E I +G +LR G+D
Sbjct: 444 VLMMPKDENEGQHMVHTALSYDEGPIAMRFPRGNGLGVKMDEQLKTIPIGTWEVLRPGND 503
Query: 189 ILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHT 248
+ + G + +A+E AE L+ G+ V++ +KP+DE+ + ++ ++ ++T+EE
Sbjct: 504 AVILTFGTTIEMAIEAAEELQKEGLSVRVVNARFIKPIDEKMMKSILKEGLPILTIEEAV 563
Query: 249 IFGGLGGAVAEALSEK-----------MPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNK 297
+ GG G ++ E ++ +P R I GS T +LL+ GL+ +
Sbjct: 564 LEGGFGSSILEFAHDQGEYHTPIDRMGIPDRFIEHGSVT---------ALLEEIGLTKQQ 614
Query: 298 VYSKV 302
V +++
Sbjct: 615 VANRI 619
>pir||G83139 1-deoxyxylulose-5-phosphate synthase PA4044 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9664861|gb|AAF97240.1|AF282878_1 (AF282878)
1-deoxy-D-xylulose 5-phosphate synthase; Dxp
[Pseudomonas aeruginosa]
>gi|9950240|gb|AAG07431.1|AE004821_4 (AE004821)
1-deoxyxylulose-5-phosphate synthase [Pseudomonas
aeruginosa]
Length = 627
Score = 140 bits (350), Expect = 2e-32
Identities = 87/268 (32%), Positives = 147/268 (54%), Gaps = 9/268 (3%)
Query: 9 FGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAG 68
FG+ L ++ ++ ++ + +K + V F ++P+R+ V I+EQ + AAG+A G
Sbjct: 330 FGQWLCDMAAQDARLLGITPAMKEGSDLVAFSERYPERYFDVAIAEQHAVTLAAGMACEG 389
Query: 69 KIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVL 128
P+V+ ++ FL RA++Q+ + +A +L+V +G DG +H DI+ +R +
Sbjct: 390 MKPVVAIYSTFLQRAYDQLIHDVAVQHLDVLFAIDRAGLVG-EDGPTHAGSFDISYLRCI 448
Query: 129 PNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPR--VYEDGDEIKLGKANILRDG 186
P M V+ P+D R LL GPA +R R P + D +++GK + R G
Sbjct: 449 PGMLVMTPSDEDELRKLLTTGYLFDGPAAVRYPRGSGPNHPIDPDLQPVEIGKGVVRRRG 508
Query: 187 SDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEE 246
+ + GV ++ A++VAE+L DA V+DM VKPLDE + LA L++T+EE
Sbjct: 509 GRVALLVFGVQLAEAMKVAESL-----DATVVDMRFVKPLDEALVRELAGSHELLVTIEE 563
Query: 247 HTIFGGLGGAVAEAL-SEKMPRRVIRIG 273
+ + GG G AV E L SE + ++++G
Sbjct: 564 NAVMGGAGSAVGEFLASEGLEVPLLQLG 591
>pir||T34693 hypothetical protein SC1C3.01 SC1C3.01 - Streptomyces coelicolor
(fragment) >gi|3169027|emb|CAA19225.1| (AL023702)
hypothetical protein SC1C3.01 [Streptomyces coelicolor
A3(2)]
Length = 341
Score = 139 bits (348), Expect = 3e-32
Identities = 99/311 (31%), Positives = 163/311 (51%), Gaps = 16/311 (5%)
Query: 9 FGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAG 68
FG ++++G++ +DV+ + A + F FPDR VGI+EQ +AAGLA G
Sbjct: 20 FGDEMLKLGKEREDVVAITAAMLQPVGLDKFAKAFPDRVYDVGIAEQHGAVSAAGLAHGG 79
Query: 69 KIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVL 128
P+ + +A FL RA++Q+ +A V V +G + DG+SH + D+++++V+
Sbjct: 80 VHPVFAVYATFLNRAFDQVLMDVALHKCGVTFVLDRAGVTG-TDGASHNGMWDMSILQVV 138
Query: 129 PNMKVVVPADAYATRALLYE-IVEDHGPAYMRLGRD-FAPRVYEDGDEIKLGKANILR-- 184
P +++ P DA RA L E +V D P +R + P V G ++G ++LR
Sbjct: 139 PGLRLAAPRDADQVRAQLREAVVVDDAPTVVRFSKGAVGPAVPAVG---RVGGMDVLRAP 195
Query: 185 --DGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
D+L V+ G + + LEVA+ L GI V+D VKP+DE + LA + +V+
Sbjct: 196 GTGTPDVLLVSVGALAPMCLEVADLLNKQGISTTVVDPRWVKPVDE-AMAPLAERHRVVV 254
Query: 243 TLEEHTIFGGLGGAVAEALSE---KMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVY 299
T+E+++ GG+G AVA+AL + +P R I +SR +L GL+ +
Sbjct: 255 TVEDNSRVGGVGSAVAQALRDAGVDVPLRDFGIPPRFLDHASR--AEVLAEIGLTAPDIA 312
Query: 300 SKVLEVVKNED 310
+V +V D
Sbjct: 313 RQVTGLVARLD 323
>pir||T35408 probable transketolase - Streptomyces coelicolor
>gi|4539172|emb|CAB39701.1| (AL049485) probable
transketolase [Streptomyces coelicolor A3(2)]
Length = 656
Score = 138 bits (345), Expect = 7e-32
Identities = 91/263 (34%), Positives = 141/263 (53%), Gaps = 7/263 (2%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ FG +V IG + DV+ + A + + F +FPDR VGI+EQ +AAG
Sbjct: 317 SWTSVFGEEIVRIGEERADVVAITAAMLHPVGLAPFAERFPDRVWDVGIAEQHAAVSAAG 376
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P+V+ +A FL RA++Q+ +A V V +G + +DG+SH + D++
Sbjct: 377 LATGGLHPVVAVYATFLNRAFDQLLMDVALHRCGVTFVLDRAGVTG-VDGASHNGMWDMS 435
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVE-DHGPAYMRLGRDFAPRVYEDGDEIKLGKANI 182
+++V+P +++ P DA R L E V D P +R ++ D ++G ++
Sbjct: 436 VLQVVPGLRIAAPRDADQLRTQLREAVAVDDAPTLLRFPKESVGPAVPAVD--RIGGLDV 493
Query: 183 LR--DGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNL 240
L D S++L VA GVM V L AE L+ GI V+D VKP+D L LA + L
Sbjct: 494 LHTADRSEVLLVAVGVMAPVCLGAAELLEARGIGCTVVDPRWVKPVDP-ALAPLAARHRL 552
Query: 241 VITLEEHTIFGGLGGAVAEALSE 263
V +E+++ G+G AVA AL +
Sbjct: 553 VAVVEDNSRAAGVGSAVALALGD 575
>dbj|BAA85847.1| (AB026631) 1-deoxy-D-xylulose 5-phosphate synthase [Streptomyces
sp. CL190]
Length = 631
Score = 136 bits (340), Expect = 3e-31
Identities = 90/264 (34%), Positives = 146/264 (55%), Gaps = 9/264 (3%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ FG +V IG + +D++ + A + + F ++FPDR VGI+EQ +AAG
Sbjct: 317 SWTSVFGDEIVRIGAEREDIVAITAAMLHPVGLARFADRFPDRVWDVGIAEQHAAVSAAG 376
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P+V+ +A FL RA++Q+ +A V V +G + +DG+SH + D++
Sbjct: 377 LATGGLHPVVAVYATFLNRAFDQLLMDVALHRCGVTFVLDRAGVTG-VDGASHNGMWDMS 435
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVE-DHGPAYMRLGRD-FAPRVYEDGDEIKLGKAN 181
+++V+P +++ P DA RA L E V D P +R ++ PR+ ++G +
Sbjct: 436 VLQVVPGLRIAAPRDADHVRAQLREAVAVDDAPTLIRFPKESVGPRIPALD---RVGGLD 492
Query: 182 ILR--DGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVN 239
+L + ++L VA GVM V L+ AE L+ GI V+D VKP+D L LA +
Sbjct: 493 VLHRDERPEVLLVAVGVMAQVCLQTAELLRARGIGCTVVDPRWVKPVDP-VLPPLAAEHR 551
Query: 240 LVITLEEHTIFGGLGGAVAEALSE 263
LV +E+++ G+G AVA AL +
Sbjct: 552 LVAVVEDNSRAAGVGSAVALALGD 575
>dbj|BAA76702.1| (AB023411) Orf462d [Deinococcus radiodurans]
Length = 272
Score = 136 bits (338), Expect = 4e-31
Identities = 79/236 (33%), Positives = 136/236 (57%), Gaps = 8/236 (3%)
Query: 39 FENQFPDRFIQVGISEQDMIGTAAGLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNV 98
F P R++ VGI+E+ + TAAG+A+ G P+V+ ++ FL RA++Q+ + +A ++LNV
Sbjct: 1 FSRVHPHRYLDVGIAEEVAVTTAAGMALQGMRPVVAIYSTFLQRAYDQVLHDVAIEHLNV 60
Query: 99 KIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHG-PAY 157
+G DG++H + D++ +R +P +++ +P DA R +L + + HG P
Sbjct: 61 TFCIDRAGIVG-ADGATHNGVFDLSFLRSIPGVRIGLPKDAAELRGML-KYAQTHGRPFA 118
Query: 158 MRLGRDFAPRV-YEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAG 216
+R R +V ++K G+ L+ G D++ +A G + AL+ AE+L GV G
Sbjct: 119 IRYPRGNTAQVPAGTWPDLKWGEWERLKGGDDVVILAGGKALDYALKAAEDLPGV----G 174
Query: 217 VLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEKMPRRVIRI 272
V++ VKPLDE L + + +IT+E++T+ GG GGAV EAL+ +R+
Sbjct: 175 VVNARFVKPLDEEMLREVGGRARALITVEDNTVVGGFGGAVLEALNSMNLHPTVRV 230
>sp|O07184|DXS_MYCTU PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
>gi|7446987|pir||E70528 probable dxs protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2181973|emb|CAB09493.1| (Z96072) dxs [Mycobacterium
tuberculosis]
Length = 638
Score = 134 bits (335), Expect = 1e-30
Identities = 86/260 (33%), Positives = 141/260 (54%), Gaps = 10/260 (3%)
Query: 8 SFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIA 67
+F L+ +K +D++ + A + T F +FPDR VGI+EQ + +AAGLA+
Sbjct: 319 TFSDALIGYAQKRRDIVAITAAMPGPTGLTAFGQRFPDRLFDVGIAEQHAMTSAAGLAMG 378
Query: 68 GKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRV 127
G P+V+ ++ FL RA++QI +A L V +V +G + DG+SH + D++++ +
Sbjct: 379 GLHPVVAIYSTFLNRAFDQIMMDVALHKLPVTMVLDRAGITG-SDGASHNGMWDLSMLGI 437
Query: 128 LPNMKVVVPADAYATRALLYEIVE-DHGPAYMR-----LGRDFAPRVYEDGDEIKLGKAN 181
+P ++V P DA R L E ++ D GP +R +G D + G ++ A+
Sbjct: 438 VPGIRVAAPRDATRLREELGEALDVDDGPTALRFPKGDVGEDISALERRGGVDVLAAPAD 497
Query: 182 ILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLV 241
L D+L VA G +AL VA+ L GI V+D V P+ + + LA + L+
Sbjct: 498 GL--NHDVLLVAIGAFAPMALAVAKRLHNQGIGVTVIDPRWVLPVSD-GVRELAVQHKLL 554
Query: 242 ITLEEHTIFGGLGGAVAEAL 261
+TLE++ + GG G AV+ AL
Sbjct: 555 VTLEDNGVNGGAGSAVSAAL 574
>sp|P57536|DXS_BUCAI 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
>gi|10039127|dbj|BAB13161.1| (AP001119) dxs protein
[Buchnera sp. APS]
Length = 608
Score = 132 bits (329), Expect = 5e-30
Identities = 88/273 (32%), Positives = 145/273 (52%), Gaps = 9/273 (3%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ + FG L EI +K +I + + + V F FP+++ V I+EQ + AAG
Sbjct: 307 SYSDVFGTWLCEIAAFDKKLIAITPAMCEGSGMVKFSRLFPNQYFDVAIAEQHAVTFAAG 366
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LAI+G P+VS ++ F RA++Q+ + IA L+V +G DG +HQ + D+A
Sbjct: 367 LAISGYKPVVSIYSTFFQRAYDQLIHDIALQKLSVLFAVDRAGIVG-NDGQTHQGVFDLA 425
Query: 124 LMRVLPNMKVVVPADAYATRALLYE-IVEDHGPAYMRLGRDF-APRVYEDGDEIKLGKAN 181
+R +P + ++ P++ R +LY + + GP+ +R + + + + I +GK+
Sbjct: 426 YLRCIPGIVIMTPSNENECRQMLYTGYMHNKGPSVVRYPKGYGVGELLMPMNRIPIGKSL 485
Query: 182 ILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLV 241
I R G I + G+++ A AE L DA ++DM VKPLD+ ++ L+ +
Sbjct: 486 IKRRGKKIAILNFGILLHNAYCAAEKL-----DATLVDMRFVKPLDKSMILKLSSQNKFF 540
Query: 242 ITLEEHTIFGGLGGAVAE-ALSEKMPRRVIRIG 273
ITLEE I GG G AV E + K+ V+ IG
Sbjct: 541 ITLEEGVISGGAGSAVNEFIMVNKIFLPVLNIG 573
>sp|Q9X291|DXS_THEMA 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
>gi|7446984|pir||A72213 1-deoxyxylulose-5-phosphate
synthase - Thermotoga maritima (strain MSB8)
>gi|4982348|gb|AAD36833.1|AE001815_7 (AE001815)
1-deoxyxylulose-5-phosphate synthase [Thermotoga
maritima]
Length = 608
Score = 132 bits (328), Expect = 6e-30
Identities = 93/315 (29%), Positives = 153/315 (48%), Gaps = 15/315 (4%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ E G TL + R++K ++ + A + + T F+ + PDRF +GI+EQ + A
Sbjct: 300 SYSELLGHTLSRVAREDKKIVAITAAMADGTGLSIFQKEHPDRFFDLGITEQTCVTFGAA 359
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
L + G P+V+ ++ FL RA++QI + +A N V SG DG +H L DI
Sbjct: 360 LGLHGMKPVVAIYSTFLQRAYDQIIHDVALQNAPVLFAIDRSGVVG-EDGPTHHGLFDIN 418
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVED-HGPAYMRLGRDF----APRVYEDGDEIKLG 178
+ +PNMK++ P+ LY +++ GP +R ++ + E+ EI LG
Sbjct: 419 YLLPVPNMKIISPSSPEEFVNSLYTVLKHLDGPVAIRYPKESFYGEVESLLENMKEIDLG 478
Query: 179 KANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV 238
IL+ G + +A+G +++ L++ +D V++ TVKPLD L +AR
Sbjct: 479 -WKILKRGREAAIIATGTILNEVLKIP-------LDVTVVNALTVKPLDTAVLKEIARDH 530
Query: 239 NLVITLEEHTIFGGLGGAVAEALSEK-MPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNK 297
+L+IT+EE GG G VA+ L E +++ +G LL GL
Sbjct: 531 DLIITVEEAMKIGGFGSFVAQRLQEMGWQGKIVNLGVEDLFVPHGGRKELLSMLGLDSEG 590
Query: 298 VYSKVLEVVKNEDDE 312
+ VL +K E
Sbjct: 591 LTKTVLTYIKARSRE 605
>gb|AAA62954.1| (U15181) transketolase [Mycobacterium leprae]
Length = 736
Score = 131 bits (326), Expect = 1e-29
Identities = 87/261 (33%), Positives = 135/261 (51%), Gaps = 10/261 (3%)
Query: 9 FGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAG 68
F L+ K +D++ + A + T F FPDR VGI+EQ + +AAGLA+
Sbjct: 413 FSDALIGYAMKRRDIVAITAAMPGPTGLTAFGQCFPDRLFDVGIAEQHAMTSAAGLAMGR 472
Query: 69 KIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVL 128
P+V+ ++ FL RA++QI +A L V +V +G + DG SH + D++++ ++
Sbjct: 473 MHPVVAIYSTFLNRAFDQIMMDVALHKLPVTMVIDRAGITG-SDGPSHNGMWDLSMLGIV 531
Query: 129 PNMKVVVPADAYATRALLYEIVE-DHGPAYMRLGR-----DFAPRVYEDGDEIKLGKANI 182
P M+V P DA R L E ++ D GP +R + D G ++ A
Sbjct: 532 PGMRVAAPRDAIRLREELGEALDVDDGPTAIRFPKGDVCEDIPALKRRSGVDVLAVPATG 591
Query: 183 LRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
L D+L V GV S+AL VA+ L GI V+D V P+ + L LA L++
Sbjct: 592 L--AQDVLLVGVGVFASMALAVAKRLHNQGIGVTVIDPRWVLPVCDGVL-ELAHTHKLIV 648
Query: 243 TLEEHTIFGGLGGAVAEALSE 263
TLE++ + GG+G AV+ AL +
Sbjct: 649 TLEDNGVNGGVGAAVSTALRQ 669
>sp|Q50000|DXS_MYCLE PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
Length = 643
Score = 131 bits (326), Expect = 1e-29
Identities = 87/261 (33%), Positives = 135/261 (51%), Gaps = 10/261 (3%)
Query: 9 FGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAG 68
F L+ K +D++ + A + T F FPDR VGI+EQ + +AAGLA+
Sbjct: 320 FSDALIGYAMKRRDIVAITAAMPGPTGLTAFGQCFPDRLFDVGIAEQHAMTSAAGLAMGR 379
Query: 69 KIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVL 128
P+V+ ++ FL RA++QI +A L V +V +G + DG SH + D++++ ++
Sbjct: 380 MHPVVAIYSTFLNRAFDQIMMDVALHKLPVTMVIDRAGITG-SDGPSHNGMWDLSMLGIV 438
Query: 129 PNMKVVVPADAYATRALLYEIVE-DHGPAYMRLGR-----DFAPRVYEDGDEIKLGKANI 182
P M+V P DA R L E ++ D GP +R + D G ++ A
Sbjct: 439 PGMRVAAPRDAIRLREELGEALDVDDGPTAIRFPKGDVCEDIPALKRRSGVDVLAVPATG 498
Query: 183 LRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
L D+L V GV S+AL VA+ L GI V+D V P+ + L LA L++
Sbjct: 499 L--AQDVLLVGVGVFASMALAVAKRLHNQGIGVTVIDPRWVLPVCDGVL-ELAHTHKLIV 555
Query: 243 TLEEHTIFGGLGGAVAEALSE 263
TLE++ + GG+G AV+ AL +
Sbjct: 556 TLEDNGVNGGVGAAVSTALRQ 576
>pir||B72215 hypothetical protein TM1762 - Thermotoga maritima (strain MSB8)
>gi|4982340|gb|AAD36826.1|AE001814_8 (AE001814)
transketolase, putative [Thermotoga maritima]
Length = 635
Score = 131 bits (325), Expect = 1e-29
Identities = 85/317 (26%), Positives = 154/317 (47%), Gaps = 19/317 (5%)
Query: 6 RESFGRTLVEIGRKNKD------VIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIG 59
R +FG+ ++++ +KN + ++ VD D+K S K + +FP+R ++VG+ E +
Sbjct: 322 RSAFGKAILDLVKKNVNNPETTPIVAVDCDLKGSVKLDLLDKEFPERLLEVGVQEHNAAA 381
Query: 60 TAAGLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCL 119
A L+ G I + F F + A + N+K+V TH G + DG +H L
Sbjct: 382 MAGALSAEGVITFFADFGVFGISETYNQHRLNAINGTNLKVVVTHCGLNVGEDGKTHHGL 441
Query: 120 EDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRV--------YED 171
+ ++ KV+VP D T ++ +++G + +GR P + + +
Sbjct: 442 DYVSGPMNWYGFKVIVPGDPNQTDRVVRYAAKEYGNFVIAMGRSKLPIILDENGKPFFGE 501
Query: 172 GDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTL 231
G + GK +++R G D + + G + A+ A+ LK G++ VL++ LD TL
Sbjct: 502 GYTFEYGKIDVVRKGDDAVIITYGSTLCEAVNAADELKKEGVNVAVLNVSCPVDLDIETL 561
Query: 232 INLARKVNLVITLEEHTIFGGLGGAVAEALSEK--MPRRVIRIGSTTFGRSSRDYLSLLD 289
+ K LV+ E+H +F GLG + L E +P++ +R+G F S Y L
Sbjct: 562 KMVDGKPVLVV--EDHNVFTGLGSFLGTTLLENGIIPKKYVRVGVPEFAVSG-SYTMLYK 618
Query: 290 RYGLSVNKVYSKVLEVV 306
YGL + + S++ E++
Sbjct: 619 LYGLDKDGIISRLREML 635
>pir||A82582 deoxyxylulose-5-phosphate synthase XF2249 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9107403|gb|AAF85048.1|AE004037_9 (AE004037)
deoxyxylulose-5-phosphate synthase [Xylella fastidiosa]
Length = 670
Score = 125 bits (312), Expect = 5e-28
Identities = 83/304 (27%), Positives = 145/304 (47%), Gaps = 9/304 (2%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+++ + F L ++ ++ + ++ + V F ++P R+ V I+EQ I AA
Sbjct: 356 QTYTDVFSEWLCDMAAVEPRLLAITPAMREGSGLVRFSQEYPQRYFDVAIAEQHAITLAA 415
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
G+A G P+V+ ++ FL R ++Q+ + +A L+V G DG++H D+
Sbjct: 416 GMATQGAKPVVAIYSTFLQRGYDQLVHDVALQKLDVLFAVDRGGVVG-PDGATHAGNLDL 474
Query: 123 ALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDG--DEIKLGKA 180
+ +R +PNM ++ PAD R +L GP +R R P V D + +G A
Sbjct: 475 SFLRCVPNMMLMAPADEAECRKMLSTGFHYSGPVAVRYPRGTGPGVVPSAELDVLPVGVA 534
Query: 181 NILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNL 240
+ G+ I + GV V+ A +V L V++M +KPLD L+ LAR
Sbjct: 535 QLRHSGTRIALLGFGVCVAPAEQVGRRL-----GLTVVNMRFIKPLDRTLLLELARTHEG 589
Query: 241 VITLEEHTIFGGLGGAVAEAL-SEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVY 299
+T+E++ + GG G VAE L +E + ++ +G + LL G+ VY
Sbjct: 590 FVTIEDNVVAGGAGSGVAELLNAEGIVLPIVHLGLPDAFQQHASREDLLAEAGIDAAGVY 649
Query: 300 SKVL 303
+ +L
Sbjct: 650 AALL 653
>pir||F71527 probable transketolase - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3328750|gb|AAC67926.1| (AE001306)
Transketolase [Chlamydia trachomatis]
Length = 640
Score = 125 bits (310), Expect = 8e-28
Identities = 91/309 (29%), Positives = 146/309 (46%), Gaps = 6/309 (1%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
SF + G L +G+K + VV + + F QFPDRF VGI+E + +AG
Sbjct: 320 SFPQHAGNILCRLGKKYPQLQVVTPAMSLGSCLEDFRKQFPDRFTDVGIAEGHAVTFSAG 379
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
+A +G S ++ FL RA + + + + L V +G + F DG SH + D+
Sbjct: 380 IARSGTPVCCSIYSTFLHRAMDNVFHDVCMQELPVIFAIDRAGLA-FHDGRSHHGIYDLG 438
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRL----GRDFAPRVYEDGDEIKLGK 179
+ +PNM + P +A L + + P +R + A + I G+
Sbjct: 439 FLCSMPNMVICQPRNALVLERLFFSSLLWKSPCAIRYPNIPANEKASNSFFPFSPILPGE 498
Query: 180 ANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVN 239
A IL G D+L +A G M + AL V E+L GI V+D +KPLD + L +L +
Sbjct: 499 AEILCQGDDLLLIALGHMCNTALTVKEHLLDYGISTTVVDPIFIKPLDRKLLQSLLTHHS 558
Query: 240 LVITLEEHTIFGGLGGAVAEALSE-KMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKV 298
VI LEEH+I GGLG L++ + V+ +G + ++L+ GL+ + +
Sbjct: 559 KVIILEEHSIHGGLGSEFLLFLNQHNIKADVLSLGVPDMFIPHGNPETILNLIGLTSDHI 618
Query: 299 YSKVLEVVK 307
++L K
Sbjct: 619 TQRILSHFK 627
>pir||A72002 1-deoxyxylulose-5-phosphate synthase CP0790 [imported] -
Chlamydophila pneumoniae (strains CWL029 and AR39)
>gi|4377395|gb|AAD19197.1| (AE001686) Transketolase
[Chlamydophila pneumoniae CWL029]
>gi|7189705|gb|AAF38589.1| (AE002238)
1-deoxyxylulose-5-phosphate synthase [Chlamydophila
pneumoniae AR39] >gi|8979433|dbj|BAA99267.1| (AP002548)
transketolase [Chlamydophila pneumoniae J138]
Length = 644
Score = 123 bits (306), Expect = 2e-27
Identities = 81/258 (31%), Positives = 126/258 (48%), Gaps = 13/258 (5%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
SF + FG+TL E+G + + VV + ++ F+ +FP+RF VGI+E + +AG
Sbjct: 324 SFPDIFGQTLCELGEVSSRLHVVTPAMSIGSRLEGFKQKFPERFFDVGIAEGHAVTFSAG 383
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
+A AG I S ++ FL RA + + + + +L V +G + + DG SH + D++
Sbjct: 384 IAKAGNPVICSIYSTFLHRALDNVFHDVCMQDLPVIFAIDRAGLA-YGDGRSHHGIYDMS 442
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEI-------- 175
+R +P M + P + LLY + P+ +R AP GD +
Sbjct: 443 FLRAMPQMIICQPRSQVVFQQLLYSSLHWSSPSAIRYPNIPAPH----GDPLTGDPNFLR 498
Query: 176 KLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLA 235
G A L G D+L +A G + AL + L GI A V+D +KP D L
Sbjct: 499 SPGNAETLSQGEDVLIIALGTLCFTALSIKHQLLAYGISATVVDPIFIKPFDNDLFSLLL 558
Query: 236 RKVNLVITLEEHTIFGGL 253
+ VIT+EEH+I GGL
Sbjct: 559 MSHSKVITIEEHSIRGGL 576
>pir||B71276 probable transketolase B (tktB) - syphilis spirochete
>gi|3323137|gb|AAC65792.1| (AE001253) transketolase B
(tktB) [Treponema pallidum]
Length = 630
Score = 122 bits (304), Expect = 4e-27
Identities = 78/267 (29%), Positives = 135/267 (50%), Gaps = 6/267 (2%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
+F E+F TL+ R + V+ + A + T F + +P+RF VGI+EQ + AAG
Sbjct: 317 TFTEAFSHTLLNAARTDDRVVAITAAMTGGTGLGLFSHIYPERFFDVGIAEQHAVTFAAG 376
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA AG P+V+ ++ FL RA +Q+ + +A NL V +G DG +HQ L D++
Sbjct: 377 LACAGVKPVVAVYSTFLQRAVDQVIHDVAVQNLPVIFALDRAGAVPH-DGETHQGLFDLS 435
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDG--DEIKLGKAN 181
++R +PN+ ++ PA A+ L + P +R + P EDG + G+
Sbjct: 436 ILRAVPNINILCPASAHELSLLFGWALAQDTPVAIRYPKALCP-PEEDGFSTPVHTGRGV 494
Query: 182 IL--RDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVN 239
++ + ++L V +G + A L GI A + ++ VKP+DE ++L +
Sbjct: 495 LITRENECNVLLVCTGGVFPEVTAAANTLARKGIFADIYNVRFVKPVDEDYFLDLVGRYR 554
Query: 240 LVITLEEHTIFGGLGGAVAEALSEKMP 266
V+ +E+ GG+ A+ L+ + P
Sbjct: 555 SVLFVEDGVKIGGIAEALQALLNTRHP 581
>pir||E81684 1-deoxyxylulose-5-phosphate synthase TC0608 [imported] - Chlamydia
muridarum (strain Nigg) >gi|7190646|gb|AAF39439.1|
(AE002329) 1-deoxyxylulose-5-phosphate synthase
[Chlamydia muridarum]
Length = 632
Score = 121 bits (300), Expect = 1e-26
Identities = 89/303 (29%), Positives = 142/303 (46%), Gaps = 4/303 (1%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
SF + G L ++G K+ + VV + + F QFPDRF VGI+E + +AG
Sbjct: 320 SFPQHVGHILCQLGEKHPRLQVVTPAMSLGSCLEDFRKQFPDRFTDVGIAEGHAVTFSAG 379
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
+A +G + S ++ FL RA + + + + L V +G + F DG SH + D+
Sbjct: 380 IARSGTPVVCSIYSTFLNRAMDNVFHDVCMQELPVIFAIDRAGLA-FHDGRSHHGIYDLG 438
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGD--EIKLGKAN 181
+ +PNM V P +A LL+ + P +R + + I G+A
Sbjct: 439 FLCSMPNMVVCQPRNASVLERLLFSSLLWKSPCAIRYPNLSTRKEVSNPSFSPIFPGEAE 498
Query: 182 ILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLV 241
+L G D+L +A G M AL V E L GI V+D +KPLD L L + V
Sbjct: 499 VLCQGDDLLLIALGHMCDTALAVKEQLLDHGISTTVVDPIFIKPLDTELLQTLLSHHSKV 558
Query: 242 ITLEEHTIFGGLGGAVAEAL-SEKMPRRVIRIGSTTFGRSSRDYLSLLDRYGLSVNKVYS 300
+ LEEH+I GGL L + + V+ +G + ++L+ GL+ +++
Sbjct: 559 VVLEEHSIHGGLSAEFLLFLNNHNLKTDVLSLGIPDIFIPHGNPETILNMIGLTSDQITL 618
Query: 301 KVL 303
K+L
Sbjct: 619 KIL 621
>sp|P26242|DXS_RHOCA PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
(PROTEIN C2814) >gi|79486|pir||G28771 hypothetical
protein C2814 (photosynthetic gene cluster) -
Rhodobacter capsulatus >gi|46140|emb|CAA77557.1|
(Z11165) 641 aa (68 kD) gene product of ORF641
[Rhodobacter capsulatus]
Length = 641
Score = 120 bits (298), Expect = 2e-26
Identities = 81/286 (28%), Positives = 144/286 (50%), Gaps = 14/286 (4%)
Query: 9 FGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAG 68
FG L E +++ ++ V A + T + +FP R VGI+EQ + AAG+A AG
Sbjct: 327 FGERLTEEAARDQAIVAVTAAMPTGTGLDIMQKRFPRRVFDVGIAEQHAVTFAAGMAAAG 386
Query: 69 KIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVL 128
P ++ +++F+ R ++Q+ + +A NL V+++ +G DG++H D++++ L
Sbjct: 387 LKPFLALYSSFVQRGYDQLVHDVALQNLPVRLMIDRAGLVG-QDGATHAGAFDVSMLANL 445
Query: 129 PNMKVVVPAD-AYATRALLYEIVEDHGPAYMRL--GRDFAPRVYEDGDEIKLGKANILRD 185
PN V+ AD A ++ D GP +R G + E G+ +++GK ++ +
Sbjct: 446 PNFTVMAAADEAELCHMVVTAAAHDSGPIALRYPRGEGRGVEMPERGEVLEIGKGRVMTE 505
Query: 186 GSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLE 245
G+++ ++ G ++ AL+ AE L+ G+ V D +PLD + L +ITLE
Sbjct: 506 GTEVAILSFGAHLAQALKAAEMLEAEGVSTTVADARFCRPLDTDLIDRLIEGHAALITLE 565
Query: 246 EHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLSLLDRY 291
+ + GG G V L+ R G GR+ R ++L D Y
Sbjct: 566 QGAM-GGFGAMVLHYLA--------RTGQLEKGRAIRT-MTLPDCY 601
>dbj|BAA99999.1| (AB019232) 1-deoxyxylulose-5-phosphate synthase; transketolase
[Arabidopsis thaliana]
Length = 604
Score = 119 bits (296), Expect = 4e-26
Identities = 83/269 (30%), Positives = 130/269 (47%), Gaps = 15/269 (5%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S+ F L+ +KD++ + A + T FE++FP R VGI+EQ + AA
Sbjct: 284 QSYTSCFVEALIAEAEADKDIVAIHAAMGGGTMLNLFESRFPTRCFDVGIAEQHAVTFAA 343
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
GLA G P + +++F+ RA++Q+ + + L V+ +G DG +H D+
Sbjct: 344 GLACEGLKPFCTIYSSFMQRAYDQVVHDVDLQKLPVRFAIDRAGLMG-ADGPTHCGAFDV 402
Query: 123 ALMRVLPNMKVVVPADAYATRALLYEIVE-----DHGPAYMRLGRDFAPRVY----EDGD 173
M LPNM V+ P+D A L+ +V D P+ R R V G
Sbjct: 403 TFMACLPNMIVMAPSD----EAELFNMVATAAAIDDRPSCFRYHRGNGIGVSLPPGNKGV 458
Query: 174 EIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLIN 233
+++G+ ILRDG + + G V LE A L G+ V D KPLD + +
Sbjct: 459 PLQIGRGRILRDGERVALLGYGSAVQRCLEAASMLSERGLKITVADARFCKPLDVALIRS 518
Query: 234 LARKVNLVITLEEHTIFGGLGGAVAEALS 262
LA+ ++IT+EE +I GG G V + L+
Sbjct: 519 LAKSHEVLITVEEGSI-GGFGSHVVQFLA 546
>emb|CAC08458.1| (AJ279019) 1-D-desoxyxylulose 5-phosphate synthase (DXS) [Narcissus
pseudonarcissus]
Length = 709
Score = 118 bits (292), Expect = 1e-25
Identities = 80/265 (30%), Positives = 130/265 (48%), Gaps = 9/265 (3%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ + F +LV+ ++ ++ + A + T +F+ +FPDR VGI+EQ + AAG
Sbjct: 390 SYTQYFAESLVKEAEVDEKIVAIHAAMGGGTGLNFFQKKFPDRCFDVGIAEQHAVTFAAG 449
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P + +++FL R ++Q+ + + L V+ +G DG +H D+
Sbjct: 450 LATEGLKPFCAIYSSFLQRGYDQVVHDVDLQKLPVRFALDRAGLVG-ADGPTHCGAFDVT 508
Query: 124 LMRVLPNMKVVVPAD-AYATRALLYEIVEDHGPAYMRLGRD-----FAPRVYEDGDEIKL 177
M LPNM V+ P+D A + D P+ R R P Y+ G +++
Sbjct: 509 YMACLPNMIVMAPSDEAELMHMVATAAAIDDRPSCFRFPRGNGVGVALPSDYK-GTPLEI 567
Query: 178 GKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARK 237
GK IL +G + + G +V L+ A +L+ GI A V D KPLD + L +
Sbjct: 568 GKGRILMEGDKVAILGYGSIVQSCLKAAGSLRERGISATVADGRFCKPLDSELIRRLVNE 627
Query: 238 VNLVITLEEHTIFGGLGGAVAEALS 262
++IT+EE +I GG V+ LS
Sbjct: 628 HEILITVEEGSI-GGFASHVSHFLS 651
>sp|Q38854|CLA1_ARATH PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE PRECURSOR (DXP
SYNTHASE) >gi|1399261|gb|AAC49368.1| (U27099) DEF
[Arabidopsis thaliana]
Length = 717
Score = 116 bits (289), Expect = 2e-25
Identities = 81/265 (30%), Positives = 128/265 (47%), Gaps = 7/265 (2%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S+ F LV +KDV+ + A + T F+ +FP R VGI+EQ + AA
Sbjct: 399 QSYTTYFAEALVAEAEVDKDVVAIHAAMGGGTGLNLFQRRFPTRCFDVGIAEQHAVTFAA 458
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
GLA G P + +++F+ RA++Q+ + + L V+ +G DG +H D+
Sbjct: 459 GLACEGLKPFCAIYSSFMQRAYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDV 517
Query: 123 ALMRVLPNMKVVVPAD-AYATRALLYEIVEDHGPAYMRLGRDFAPRVY----EDGDEIKL 177
M LPNM V+ P+D A + + D P+ R R V G I++
Sbjct: 518 TFMACLPNMIVMAPSDEADLFNMVATAVAIDDRPSCFRYPRGNGIGVALPPGNKGVPIEI 577
Query: 178 GKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARK 237
GK IL++G + + G V L A L+ G++ V D KPLD + +LA+
Sbjct: 578 GKGRILKEGERVALLGYGSAVQSCLGAAVMLEERGLNVTVADARFCKPLDRALIRSLAKS 637
Query: 238 VNLVITLEEHTIFGGLGGAVAEALS 262
++IT+EE +I GG G V + L+
Sbjct: 638 HEVLITVEEGSI-GGFGSHVVQFLA 661
>emb|CAA74713.1| (Y14333) transketolase [Arabidopsis thaliana]
Length = 739
Score = 116 bits (289), Expect = 2e-25
Identities = 81/265 (30%), Positives = 128/265 (47%), Gaps = 7/265 (2%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S+ F LV +KDV+ + A + T F+ +FP R VGI+EQ + AA
Sbjct: 421 QSYTTYFAEALVAEAEVDKDVVAIHAAMGGGTGLNLFQRRFPTRCFDVGIAEQHAVTFAA 480
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
GLA G P + +++F+ RA++Q+ + + L V+ +G DG +H D+
Sbjct: 481 GLACEGLKPFCAIYSSFMQRAYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDV 539
Query: 123 ALMRVLPNMKVVVPAD-AYATRALLYEIVEDHGPAYMRLGRDFAPRVY----EDGDEIKL 177
M LPNM V+ P+D A + + D P+ R R V G I++
Sbjct: 540 TFMACLPNMIVMAPSDEADLFNMVATAVAIDDRPSCFRYPRGNGIGVALPPGNKGVPIEI 599
Query: 178 GKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARK 237
GK IL++G + + G V L A L+ G++ V D KPLD + +LA+
Sbjct: 600 GKGRILKEGERVALLGYGSAVQSCLGAAVMLEERGLNVTVADARFCKPLDRALIRSLAKS 659
Query: 238 VNLVITLEEHTIFGGLGGAVAEALS 262
++IT+EE +I GG G V + L+
Sbjct: 660 HEVLITVEEGSI-GGFGSHVVQFLA 683
>emb|CAB45992.1| (Z97339) DEF (CLA1) protein [Arabidopsis thaliana]
>gi|7268304|emb|CAB78598.1| (AL161542) DEF (CLA1)
protein [Arabidopsis thaliana]
Length = 717
Score = 116 bits (289), Expect = 2e-25
Identities = 81/265 (30%), Positives = 128/265 (47%), Gaps = 7/265 (2%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S+ F LV +KDV+ + A + T F+ +FP R VGI+EQ + AA
Sbjct: 399 QSYTTYFAEALVAEAEVDKDVVAIHAAMGGGTGLNLFQRRFPTRCFDVGIAEQHAVTFAA 458
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
GLA G P + +++F+ RA++Q+ + + L V+ +G DG +H D+
Sbjct: 459 GLACEGLKPFCAIYSSFMQRAYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDV 517
Query: 123 ALMRVLPNMKVVVPAD-AYATRALLYEIVEDHGPAYMRLGRDFAPRVY----EDGDEIKL 177
M LPNM V+ P+D A + + D P+ R R V G I++
Sbjct: 518 TFMACLPNMIVMAPSDEADLFNMVATAVAIDDRPSCFRYPRGNGIGVALPPGNKGVPIEI 577
Query: 178 GKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARK 237
GK IL++G + + G V L A L+ G++ V D KPLD + +LA+
Sbjct: 578 GKGRILKEGERVALLGYGSAVQSCLGAAVMLEERGLNVTVADARFCKPLDRALIRSLAKS 637
Query: 238 VNLVITLEEHTIFGGLGGAVAEALS 262
++IT+EE +I GG G V + L+
Sbjct: 638 HEVLITVEEGSI-GGFGSHVVQFLA 661
>emb|CAA09804.1| (AJ011840) 1-deoxyxylulose 5-phosphate synthase [Catharanthus
roseus]
Length = 716
Score = 116 bits (288), Expect = 3e-25
Identities = 81/264 (30%), Positives = 126/264 (47%), Gaps = 7/264 (2%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ + F +L++ + +I + A + T YF+ +FPDR VGI+EQ + AAG
Sbjct: 397 SYTQYFAESLIKEAEIDNKIIAIHAAMGGGTGLNYFQKRFPDRCFDVGIAEQHAVTFAAG 456
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P + +++FL R ++Q+ + + L V+ +G DG +H D+A
Sbjct: 457 LATEGLKPFCAIYSSFLQRGYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDVA 515
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVE-DHGPAYMRL----GRDFAPRVYEDGDEIKLG 178
M LPNM V+ P+D ++ + D P R G A G +++G
Sbjct: 516 YMACLPNMIVMAPSDEAELMHMVATAAKIDDRPCCFRFPRGNGIGVALPPNNKGTPLEIG 575
Query: 179 KANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV 238
K IL +GS + + G +V L AE LK + V D KPLD LA++
Sbjct: 576 KGRILVEGSRVAILGYGSIVQQCLGAAEMLKSHNVSPTVADARFCKPLDGILSKTLAKEH 635
Query: 239 NLVITLEEHTIFGGLGGAVAEALS 262
++IT+EE +I G G V LS
Sbjct: 636 EILITVEEGSI-GAFGSHVTHFLS 658
>pir||T08140 1-deoxy-D-xylulose-5-phosphate synthase precursor - Chlamydomonas
reinhardtii >gi|4185881|emb|CAA07554.1| (AJ007559)
1-deoxy-D-xylulose-5-phosphate synthase [Chlamydomonas
reinhardtii]
Length = 735
Score = 115 bits (285), Expect = 7e-25
Identities = 80/268 (29%), Positives = 131/268 (48%), Gaps = 15/268 (5%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ F L ++ ++ V A + T FE +FPDR VGI+EQ + AAG
Sbjct: 405 SYTNYFADALTAEAERDSRIVAVHAAMAGGTGLYRFEKKFPDRTFDVGIAEQHAVTFAAG 464
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G +P + ++ F+ R ++QI + ++ L V+ +G DGS+H D+
Sbjct: 465 LACEGLVPFCTIYSTFMQRGYDQIVHDVSLQKLPVRFAMDRAGLVG-ADGSTHCGAFDVT 523
Query: 124 LMRVLPNMKVVVPA-DAYATRALLYEIVEDHGPAYMR------LGRDFAP-RVYED--GD 173
M LP+M + P+ +A + D P+ R LG D A + +D G
Sbjct: 524 FMASLPHMITMAPSNEAELINMVATCAAIDDAPSCFRFPRGNGLGLDLAAYGISKDLKGV 583
Query: 174 EIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLIN 233
+++GK + R G D+ VA G V+ AL A+ L+ G+ V+D KPLD + + +
Sbjct: 584 PLEVGKGVVRRQGKDVCLVAYGSSVNEALAAADMLERDGVSTTVIDARFCKPLDTKLIRS 643
Query: 234 LARKVNLVITLEEHTIFGGLGGAVAEAL 261
A++ ++IT+EE G +GG A +
Sbjct: 644 AAKEHPVMITIEE----GSVGGFAAHVM 667
>emb|CAB96673.1| (AL360314) 1-D-deoxyxylulose 5-phosphate synthase-like protein
[Arabidopsis thaliana]
Length = 700
Score = 114 bits (283), Expect = 1e-24
Identities = 81/268 (30%), Positives = 130/268 (48%), Gaps = 16/268 (5%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
++ + F LV K++D++VV A ++ + F+ +FPDRF VG++EQ + +AG
Sbjct: 381 TYSDCFVEALVMEAEKDRDIVVVHAGMEMDPSLLTFQERFPDRFFNVGMAEQHAVTFSAG 440
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
L+ G P +AFL RA++Q+ + + R V+ V T +G DG DIA
Sbjct: 441 LSSGGLKPFCIIPSAFLQRAYDQVVHDVDRQRKAVRFVITSAGLVG-SDGPVQCGAFDIA 499
Query: 124 LMRVLPNMKVVVPAD------AYATRALLYEIVEDHGPAYMRLGRDFAPR---VYEDGDE 174
M LPNM + PAD AT A + + P R R + G
Sbjct: 500 FMSSLPNMIAMAPADEDELVNMVATAAYVTD-----RPVCFRFPRGSIVNMNYLVPTGLP 554
Query: 175 IKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINL 234
I++G+ +L +G D+ + G MV L L +G++ V D KPLD + + +L
Sbjct: 555 IEIGRGRVLVEGQDVALLGYGAMVQNCLHAHSLLSKLGLNVTVADARFCKPLDIKLVRDL 614
Query: 235 ARKVNLVITLEEHTIFGGLGGAVAEALS 262
+ +IT+EE + GG G VA+ ++
Sbjct: 615 CQNHKFLITVEEGCV-GGFGSHVAQFIA 641
>pir||E81451 1-deoxyxylulose-5-phosphate synthase Cj0321 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6967795|emb|CAB72788.1| (AL139074)
1-deoxyxylulose-5-phosphate synthase [Campylobacter
jejuni]
Length = 615
Score = 114 bits (282), Expect = 2e-24
Identities = 76/269 (28%), Positives = 136/269 (50%), Gaps = 15/269 (5%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S E F + L+++ K ++++ V A + + T ++P+RF V I+EQ + + A
Sbjct: 309 KSATEIFSKNLLDLASKYENIVGVTAAMPSGTGLDKLIEKYPNRFWDVAIAEQHAVTSMA 368
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
+A G P ++ ++ FL RA++Q+ + A NLNV +G DG +HQ + D+
Sbjct: 369 AMAKEGFKPFIAIYSTFLQRAYDQVIHDCAIMNLNVVFAMDRAGIVG-EDGETHQGVFDL 427
Query: 123 ALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMR-------LGRDFAPRVYEDGDEI 175
+ + LPN ++ P D + ++ GP +R L ++F P EI
Sbjct: 428 SFLAPLPNFTLLAPRDEQMMQNIMEYAYLHQGPIALRYPRGSFILDKEFNP------CEI 481
Query: 176 KLGKAN-ILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINL 234
KLGKA ++++ S+I F+ G V+ A +V L+ + +A ++D+ KPLDE L L
Sbjct: 482 KLGKAQWLVKNNSEIAFLGYGQGVAKAWQVLRALQEMNNNANLIDLIFAKPLDEELLCEL 541
Query: 235 ARKVNLVITLEEHTIFGGLGGAVAEALSE 263
A+K + E+ GG+ + L +
Sbjct: 542 AKKSKIWFIFSENVKIGGIESLINNFLQK 570
>gb|AAC33513.1| (AF019383) 1-deoxyxylulose-5-phosphate synthase [Mentha x piperita]
Length = 724
Score = 113 bits (281), Expect = 2e-24
Identities = 77/265 (29%), Positives = 128/265 (48%), Gaps = 7/265 (2%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S+ + F +LV + ++ + A + T F+ QFPDR VGI+EQ + AA
Sbjct: 401 KSYTQYFAESLVAEAEHDDKIVAIHAAMGGGTGLNIFQKQFPDRCFDVGIAEQHAVTFAA 460
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
G+A G P + +++FL R ++Q+ + + L V+ + +G DG +H D
Sbjct: 461 GMAAEGLKPFCAIYSSFLQRGYDQVVHDVDLQKLPVRFMMDRAGVVG-ADGPTHCGAFDT 519
Query: 123 ALMRVLPNMKVVVPAD-AYATRALLYEIVEDHGPAYMRL----GRDFAPRVYEDGDEIKL 177
M LPNM V+ P+D A + + D P+ +R G A G +++
Sbjct: 520 TYMACLPNMVVMAPSDEAELMNMIATAAIIDDRPSCVRYPRGNGIGVALPSNNKGTPLEI 579
Query: 178 GKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARK 237
GK IL++GS + + G +V + A L+ GI V D KPLD + L ++
Sbjct: 580 GKGRILKEGSKVAILGFGTIVQNCMAAANLLEQHGISVTVADARFCKPLDGDLIKKLVQE 639
Query: 238 VNLVITLEEHTIFGGLGGAVAEALS 262
++IT+EE +I GG ++ LS
Sbjct: 640 HEVLITVEEGSI-GGFSAHISHFLS 663
>gb|AAD38941.1|AF143812_1 (AF143812) 1-D-deoxyxylulose 5-phosphate synthase [Lycopersicon
esculentum]
Length = 719
Score = 111 bits (276), Expect = 8e-24
Identities = 79/269 (29%), Positives = 128/269 (47%), Gaps = 15/269 (5%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S+ F L+ +KD++ + A + T F +FP R VGI+EQ + AA
Sbjct: 398 QSYTTYFAEALIAEAEADKDIVAIHAAMGGGTGMNLFHRRFPTRCFDVGIAEQHAVTFAA 457
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
GLA G P + +++F+ RA++Q+ + + L V+ +G DG +H D+
Sbjct: 458 GLACEGIKPFCAIYSSFMQRAYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDV 516
Query: 123 ALMRVLPNMKVVVPADAYATRALLYEIVE-----DHGPAYMRLGRDFAPRVY----EDGD 173
M LPNM V+ P+D A L+ +V D P+ R R V G
Sbjct: 517 TYMACLPNMVVMAPSD----EAELFHMVATAAAIDDRPSCFRYPRGNGIGVELPAGNKGI 572
Query: 174 EIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLIN 233
+++GK IL +G + + G V L+ A L+ G+ V D KPLD + +
Sbjct: 573 PLEVGKGRILIEGERVALLGYGSAVQNCLDAAIVLESRGLQVTVADARFCKPLDHALIRS 632
Query: 234 LARKVNLVITLEEHTIFGGLGGAVAEALS 262
LA+ ++IT+EE +I GG G V + ++
Sbjct: 633 LAKSHEVLITVEEGSI-GGFGSHVVQFMA 660
>pir||T09543 deoxyxylulose synthase (EC 2.2.1.-) TKT2 precursor, chloroplast
[validated] - pepper >gi|3559816|emb|CAA75778.1|
(Y15782) transketolase 2 [Capsicum annuum]
Length = 719
Score = 110 bits (273), Expect = 2e-23
Identities = 78/269 (28%), Positives = 127/269 (46%), Gaps = 15/269 (5%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S+ F L+ +KD++ + A + T F +FP R VGI+EQ + AA
Sbjct: 398 QSYTTYFAEALIAEAEADKDIVAIHAAMGGGTGMNLFLRRFPTRCFDVGIAEQHAVTFAA 457
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
GLA G P + +++F+ RA++Q+ + + L V+ +G DG +H D+
Sbjct: 458 GLACEGLKPFCAIYSSFMQRAYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDV 516
Query: 123 ALMRVLPNMKVVVPADAYATRALLYEIVE-----DHGPAYMRLGRDFAPRVY----EDGD 173
M LPNM V+ P+D A L+ IV D P+ R R V G
Sbjct: 517 TFMACLPNMVVMAPSD----EAELFHIVATAAAIDDRPSCFRYPRGNGIGVELPAGNKGI 572
Query: 174 EIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLIN 233
+++GK IL +G + + G V L A L+ G+ V D KPLD + +
Sbjct: 573 PLEVGKGRILVEGERVALLGYGSAVQNCLAAASVLESRGLQVTVADARFCKPLDRALIRS 632
Query: 234 LARKVNLVITLEEHTIFGGLGGAVAEALS 262
LA+ +++T+E+ +I GG G V + ++
Sbjct: 633 LAKSHEVLVTVEKGSI-GGFGSHVVQFMA 660
>dbj|BAB04496.1| (AP001509) acetoin dehydrogenase (TPP-dependent) beta chain
[Bacillus halodurans]
Length = 327
Score = 109 bits (270), Expect = 4e-23
Identities = 87/278 (31%), Positives = 131/278 (46%), Gaps = 22/278 (7%)
Query: 2 IESFRESFGRTLVEIGRKNKDVIVVDADV-----KNSTKTVYFENQFPDRFIQVGISEQD 56
+E+ RE+ + RKN+DV ++ D+ E +R ISE
Sbjct: 7 LEAIREAMTLEM----RKNEDVFILGEDIGVYGGAFGVTRGMIEEFGSERVRNTPISEAA 62
Query: 57 MIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIARDNLNV-------KIVATHSGFS 108
+ GTA G A+ G PI+ F+ F+ A + + N A+ ++ T +G
Sbjct: 63 ISGTAIGAALTGMRPILELQFSDFITIAMDNMVNQAAKLRYMYGGKAKVPMVLRTPAGSG 122
Query: 109 DFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYM---RLGRDFA 165
Q LE A M +P +KVV PA AY + LL ++D+ P +L
Sbjct: 123 TGAAAQHSQSLE--AWMTHIPGLKVVQPATAYDAKGLLKAAIDDNNPVIFYEHKLCYRTK 180
Query: 166 PRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKP 225
V E+ I LGKA++ R G+D+ VA+ VMV ALE A L+ GI V+D T+ P
Sbjct: 181 CHVPEEEYSIPLGKADVKRKGTDVTVVATAVMVHKALEAAVELEKEGISVEVIDPRTLVP 240
Query: 226 LDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSE 263
LDE T+I +K + +I + E GG GG +A ++E
Sbjct: 241 LDEETIIRSVKKTSRLIVVHEAVKRGGFGGEIASIIAE 278
>gb|AAG10432.1| (AF251020) 1-deoxy-D-xylulose-5-phosphate synthase [Tagetes erecta]
Length = 725
Score = 108 bits (268), Expect = 7e-23
Identities = 76/265 (28%), Positives = 127/265 (47%), Gaps = 9/265 (3%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ + F +LV +++ ++ + A + T F+ +FP R VGI+EQ I AAG
Sbjct: 404 SYTQYFVDSLVAEAKEDDKIVAIHAAMGGGTGLNTFQKEFPARCFDVGIAEQHAITFAAG 463
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P + +++FL R ++Q+ + + L V+ +G DG +H D
Sbjct: 464 LATEGLKPFCAIYSSFLQRGYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDTT 522
Query: 124 LMRVLPNMKVVVPA-DAYATRALLYEIVEDHGPAYMRLGR-----DFAPRVYEDGDEIKL 177
M LPNM V+ P+ +A + + D P+ R R P G I++
Sbjct: 523 FMACLPNMVVMAPSCEAELMNMVATAVAIDDRPSCFRYPRGNGIGSILP-ANNKGTLIEV 581
Query: 178 GKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARK 237
G ++++G+ + + G +V L +E LK +GI V D KPLD + LA +
Sbjct: 582 GTGRVIKEGNRVALLGYGTIVQSCLAASEVLKKIGISVTVADARFCKPLDGNLIKQLANE 641
Query: 238 VNLVITLEEHTIFGGLGGAVAEALS 262
++IT+EE +I GG V+ L+
Sbjct: 642 HEVLITVEEGSI-GGFSSHVSHFLA 665
>sp|O22567|CLA1_ORYSA PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)
>gi|7446975|pir||T02208 transketolase-like protein -
rice (fragment) >gi|2612941|gb|AAB88295.1| (AF024512)
CLA1 transketolase-like protein [Oryza sativa]
Length = 594
Score = 108 bits (267), Expect = 9e-23
Identities = 76/265 (28%), Positives = 125/265 (46%), Gaps = 9/265 (3%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ F L+ ++ V+ + A + T YF +FP+R VGI+EQ + AAG
Sbjct: 320 SYTNYFAEALIAEAEQDNRVVAIHAAMGGGTGLNYFLRRFPNRCFDVGIAEQHAVTFAAG 379
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P + +++FL R ++Q+ + + L V+ +G DG +H D+
Sbjct: 380 LACEGLKPFCAIYSSFLQRGYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDVT 438
Query: 124 LMRVLPNMKVVVPAD-AYATRALLYEIVEDHGPAYMRLGRDFA-----PRVYEDGDEIKL 177
M LPNM V+ P+D A + D P+ R R P Y+ G +++
Sbjct: 439 YMACLPNMVVMAPSDEAELCHMVATAAAIDDRPSCFRYPRGNGIGVPLPPNYK-GVPLEV 497
Query: 178 GKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARK 237
GK +L +G + + G V L A ++ G+ V D KPLD+ + LA
Sbjct: 498 GKGRVLLEGERVALLGYGSAVQYCLAAASLVERHGLKVTVADARFCKPLDQTLIRRLASS 557
Query: 238 VNLVITLEEHTIFGGLGGAVAEALS 262
+++T+EE +I GG G VA+ ++
Sbjct: 558 HEVLLTVEEGSI-GGFGSHVAQFMA 581
>pir||H71946 1-deoxyxylulose-5-phosphate synthase - Helicobacter pylori (strain
J99) >gi|4154849|gb|AAD05902.1| (AE001468)
1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE [Helicobacter
pylori J99]
Length = 618
Score = 108 bits (266), Expect = 1e-22
Identities = 77/262 (29%), Positives = 134/262 (50%), Gaps = 7/262 (2%)
Query: 7 ESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAI 66
E++ TL+E+ +K++ ++ V A + + T + +P RF V I+EQ + +++ +A
Sbjct: 313 EAYSNTLLELAKKDEKIVGVTAAMPSGTGLDKLIDAYPLRFFDVAIAEQHALTSSSAMAK 372
Query: 67 AGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMR 126
G P VS ++ FL RA++ I + +L +K+ +G DG +HQ L D++ +R
Sbjct: 373 EGFKPFVSIYSTFLQRAYDSIVHDACISSLPIKLAIDRAGIVG-EDGETHQGLLDVSYLR 431
Query: 127 VLPNMKVVVPADAYATRALLYEIVE-DHGPAYMRLGR-DFAPR--VYEDGDEIKLGKANI 182
+PNM + P D + +Y E D P R R FA + V+E + LG++ +
Sbjct: 432 SIPNMVIFAPRDNETLKNAVYFANEHDSSPCAFRYPRGSFALKEGVFEPSGFV-LGRSEL 490
Query: 183 LRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
L+ +IL + G V A V LK I+ +LD+ +KPLD +A L +
Sbjct: 491 LKKEGEILLIGYGNGVGRAHLVQLALKEKNIECALLDLRFLKPLDHNLSAIIAPYQKLYV 550
Query: 243 TLEEHTIFGGLGGAVAEALSEK 264
+ + + GG+ A+ E LSE+
Sbjct: 551 FSDNYKL-GGVASAILEFLSEQ 571
>emb|CAC17468.1| (AJ291721) 1-D-deoxyxylulose 5-phosphate synthase [Nicotiana
tabacum]
Length = 294
Score = 108 bits (266), Expect = 1e-22
Identities = 79/264 (29%), Positives = 123/264 (45%), Gaps = 17/264 (6%)
Query: 9 FGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAG 68
F L+ +KD++ + A + T F +FP R VGI+EQ + AAGLA G
Sbjct: 5 FAEALIAEAEADKDIVAIHAAMGGGTGMNLFHRRFPTRCFDVGIAEQHAVTFAAGLACEG 64
Query: 69 KIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVL 128
P + +++FL RA++Q+ + + L V+ +G DG +H D+ M L
Sbjct: 65 LKPFCAIYSSFLQRAYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDVTFMACL 123
Query: 129 PNMKVVVPAD------AYATRALLYEIVEDHGPAYMRL----GRDFAPRVYEDGDEIKLG 178
PNM V+ P+D AT A + D P+ R G V G +++G
Sbjct: 124 PNMVVMAPSDETELFHMVATAAAI-----DDRPSCFRYPRGNGIGVELPVGNKGTPLEVG 178
Query: 179 KANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKV 238
K IL +G + + G V L A L+ G+ V D K LD + +LA+
Sbjct: 179 KGRILVEGERVALLGYGSAVQNCLAAAAVLESRGLQVTVADAPFCKRLDHALIRSLAKSH 238
Query: 239 NLVITLEEHTIFGGLGGAVAEALS 262
++IT+EE +I GG G VA+ ++
Sbjct: 239 EVLITVEEGSI-GGFGSHVAQFMA 261
>pir||B64564 transketolase B - Helicobacter pylori (strain 26695)
>gi|2313455|gb|AAD07422.1| (AE000552)
deoxyxylulose-5-phosphate synthase, putative (dxs)
[Helicobacter pylori 26695]
Length = 618
Score = 105 bits (260), Expect = 6e-22
Identities = 76/262 (29%), Positives = 134/262 (51%), Gaps = 7/262 (2%)
Query: 7 ESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAI 66
E++ TL+E+ +K++ ++ V A + + T + +P RF V I+EQ + +++ +A
Sbjct: 313 EAYSNTLLELAKKDEKIVGVTAAMPSGTGLDKLIDAYPLRFFDVAIAEQHALTSSSAMAK 372
Query: 67 AGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMR 126
G P VS ++ FL RA++ I + +L +K+ +G DG +HQ L D++ +R
Sbjct: 373 EGFKPFVSIYSTFLQRAYDSIVHDACISSLPIKLAIDRAGIVG-EDGETHQGLLDVSYLR 431
Query: 127 VLPNMKVVVPADAYATR-ALLYEIVEDHGPAYMRLGR-DFAPR--VYEDGDEIKLGKANI 182
+PNM + P D + A+ + D P R R FA + V+E + LG++ +
Sbjct: 432 SIPNMVIFAPRDNETLKNAVRFANEHDSSPCAFRYPRGSFALKEGVFEPSGFV-LGQSEL 490
Query: 183 LRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
L+ +IL + G V A V LK I+ +LD+ +KPLD +A L +
Sbjct: 491 LKKEGEILLIGYGNGVGRAHLVQLALKEKNIECALLDLRFLKPLDPNLSAIVAPYQKLYV 550
Query: 243 TLEEHTIFGGLGGAVAEALSEK 264
+ + + GG+ A+ E LSE+
Sbjct: 551 FSDNYKL-GGVASAILEFLSEQ 571
>dbj|BAA83576.1| (AP000399) ESTs AU078063(S15496),C97608(C60475), C28255(C60475)
correspond to a region of the predicted gene.~Similar to
plastid transketolase 2 (Y15782) [Oryza sativa]
Length = 628
Score = 105 bits (260), Expect = 6e-22
Identities = 80/268 (29%), Positives = 129/268 (47%), Gaps = 16/268 (5%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
++ + F +L+ +K ++VV + F+++FPDRF +GI+EQ + +AG
Sbjct: 355 TYNDCFVESLIAEAENDKHIVVVHGGMGIDRSIQLFQSRFPDRFFDLGIAEQHAVTFSAG 414
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA G P + FL RA++QI + + V+ T +G +G ++ DI
Sbjct: 415 LACGGLKPFCIIPSTFLQRAYDQIVEDVDMQKIPVRFAITSAGLVG-SEGPTNSGPFDIT 473
Query: 124 LMRVLPNMKVVVPA------DAYATRALLYEIVEDHGPAYMRLGRDF---APRVYEDGDE 174
M LPNM V+ P+ D AT A+ VED P R + G+
Sbjct: 474 FMSCLPNMIVMSPSNEDELIDMVATAAM----VEDR-PICFRYPKGAIVGTSGTLAYGNP 528
Query: 175 IKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINL 234
+++GK IL +G +I F+ G +V L L GI A V + KPLD + L
Sbjct: 529 LEIGKGEILAEGKEIAFLGYGDVVQRCLIARSLLFNFGIQATVANARFCKPLDIDLIRML 588
Query: 235 ARKVNLVITLEEHTIFGGLGGAVAEALS 262
++ + +IT+EE T+ GG G V++ +S
Sbjct: 589 CQQHDFLITVEEGTV-GGFGSHVSQFIS 615
>dbj|BAB06373.1| (AP001516) pyruvate dehydrogenase E1 (lipoamide) beta subunit
[Bacillus halodurans]
Length = 325
Score = 105 bits (259), Expect = 8e-22
Identities = 72/262 (27%), Positives = 124/262 (46%), Gaps = 15/262 (5%)
Query: 18 RKNKDVIVVDADVKNS----TKTVYFENQF-PDRFIQVGISEQDMIGTAAGLAIAGKIPI 72
+++++V+V DV + T + +F DR ++E + G A GL + G P+
Sbjct: 19 KRDENVLVFGEDVGQNGGVFRATEGLQKEFGEDRVFDTPLAESGIGGLAIGLGLTGFRPV 78
Query: 73 VSA-FAAFLMRAWEQIRNTIARDNLNV-----KIVATHSGFSDFLDGSSHQCLEDIALMR 126
+ F F+ ++ + +AR + S F + LM
Sbjct: 79 MEVQFFGFVFEVFDSVAGQMARMRYRSGGKYHSPITVRSPFGGGVKTPELHADNLEGLMA 138
Query: 127 VLPNMKVVVPADAYATRALLYEIVEDHGPA----YMRLGRDFAPRVYEDGDEIKLGKANI 182
P +KVV+P+ Y + LL + D+ P +M+L R F V E+ I LGKA++
Sbjct: 139 QTPGVKVVIPSTPYDAKGLLISAIRDNDPVIYLEHMKLYRSFRAEVPEEEYTIPLGKADV 198
Query: 183 LRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
R+G D+ + G MV +L+ AE L+ GI A V+D+ T+ P+D T++ +K + VI
Sbjct: 199 KREGKDVSIITYGAMVHSSLKAAEELEKEGISAEVIDLRTISPIDIDTILESVKKTSRVI 258
Query: 243 TLEEHTIFGGLGGAVAEALSEK 264
++E G+G VA + E+
Sbjct: 259 VVQEAQKQAGIGAHVASEIQER 280
>gb|AAK41604.1| Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-1)
[Sulfolobus solfataricus]
Length = 332
Score = 104 bits (258), Expect = 1e-21
Identities = 82/272 (30%), Positives = 130/272 (47%), Gaps = 30/272 (11%)
Query: 19 KNKDVIVVDADVKNSTKTVYFENQFPDRF-----IQVGISEQDMIGTAAGLAIAGKIPIV 73
+N ++V+ DV F D+F I I+EQ +G + G A +G P+V
Sbjct: 20 RNDRIVVLGEDVTYWGAVFGFTMGLFDKFGRKRVIDTPITEQTFMGISVGAASSGLHPVV 79
Query: 74 SA-FAAFLMRAWEQIRNTIARDNLN---------VKIVATHSGFSDFLDGSSHQCLEDIA 123
S F FL ++Q+ N +A++ I A G+ D SS +
Sbjct: 80 SLMFVDFLGAGFDQMFNHMAKNYYMSGGQYPMPITVITAIGGGYGD----SSQHSQVLYS 135
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY-----MRLGRDFAP------RVYEDG 172
L LP KV+VP+ Y + L + + D+ P + G F P V E+
Sbjct: 136 LFAHLPGFKVIVPSTPYDAKGLTIKALRDNNPVIIFGHKLLTGLPFLPFEGNEEEVPEEP 195
Query: 173 DEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLI 232
EI+ GKA I ++G+D+ +++G+MV +L+ AE L+ GI A V+D+ T PLDE T+I
Sbjct: 196 YEIEFGKAAIRKEGTDLTIISAGLMVHRSLKAAEMLQKEGISAEVIDVRTFVPLDEETII 255
Query: 233 NLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
ARK V+ ++E + G+ G +A + K
Sbjct: 256 KSARKTGRVLIVDEDYMSYGVTGEIAFRIQSK 287
>gb|AAD56390.2|AF182286_1 (AF182286) 1-deoxy-D-xylulose-5-phosphate synthase [Artemisia
annua]
Length = 713
Score = 104 bits (258), Expect = 1e-21
Identities = 77/269 (28%), Positives = 125/269 (45%), Gaps = 15/269 (5%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S+ F L+ +K ++ + A + T F +FP R VGI+EQ + AA
Sbjct: 392 QSYTTYFAEALIAEAEADKKIVGIHAAMGGGTGMNLFLRRFPTRCFDVGIAEQHAVTFAA 451
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
GLA G P + +++FL R ++Q+ + + L V+ +G DG +H D+
Sbjct: 452 GLACEGLKPFCAIYSSFLQRGYDQVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHSGSFDV 510
Query: 123 ALMRVLPNMKVVVPADAYATRALLYEIVE-----DHGPAYMRLGRDFAPRV----YEDGD 173
M LPNM V+ P+D A L+ +V D P+ R R V G
Sbjct: 511 TFMACLPNMVVMAPSD----EAELFNMVATAAAIDDRPSCFRYPRGNGIGVPLPPGNKGV 566
Query: 174 EIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLIN 233
+++GK I+ +G + + G V + A ++ G++ V D KPLD +
Sbjct: 567 PLEVGKGRIMLEGQRVALLGYGTAVQSCMAAATIVQERGLNITVADARFCKPLDHSLIRA 626
Query: 234 LARKVNLVITLEEHTIFGGLGGAVAEALS 262
LA+ ++IT+EE +I GG G VA L+
Sbjct: 627 LAKTHEVLITVEEGSI-GGFGSHVAHFLA 654
>dbj|BAB03933.1| (AP001507) pyruvate dehydrogenase E1 (lipoamide) beta subunit
[Bacillus halodurans]
Length = 328
Score = 101 bits (249), Expect = 1e-20
Identities = 79/280 (28%), Positives = 132/280 (46%), Gaps = 20/280 (7%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVK------NSTKTVYFENQFPDRFIQVGISEQD 56
++ ++ +TL ++ N DV+++ D+ +T +Y E DR + ++E
Sbjct: 6 QTMLQAINQTLDDLLATNDDVMLLGEDIGINGGVFRATDGLY-EKYGKDRVVDTPLAESG 64
Query: 57 MIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLNVKIVATHSGFSD 109
+IG+A GLA+ GK PIV F AF+ +EQ+ + AR NV +V + +
Sbjct: 65 IIGSAIGLAMNGKRPIVEIQFLAFIYPGFEQLISHAARMRYRTRGQYNVPMVI-RTPYGA 123
Query: 110 FLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYM----RLGRDFA 165
+ G A P +KVV P++ Y + LL D P +L R F
Sbjct: 124 GIRGPELHSESVEAFFAHTPGLKVVAPSNPYDAKGLLTAATSDPDPVIFLEDTKLYRAFK 183
Query: 166 PRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENL-KGVGIDAGVLDMHTVK 224
V EI LG+A ++++G D+ +A G MV AL+ A+ K G ++D+ T+
Sbjct: 184 EDVPNTLYEIPLGQAKVVQEGEDVTVIAWGGMVREALQAAKEAEKAHGWSCEIIDLRTIA 243
Query: 225 PLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
P+D T+I +K I + E GLGG + ++E+
Sbjct: 244 PIDRETIIESVKKTGRAIIIHEAHKTAGLGGEITALINEE 283
>gb|AAF36410.1|AF235026_1 (AF235026) pyruvate dehydrogenase beta subunit PdhB [Staphylococcus
aureus]
Length = 325
Score = 101 bits (248), Expect = 2e-20
Identities = 71/262 (27%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 18 RKNKDVIVVDADVKNS----TKTVYFENQF-PDRFIQVGISEQDMIGTAAGLAIAGKIPI 72
+ ++DV++ DV + T + +F DR ++E + G A GLA+ G P+
Sbjct: 19 KNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPV 78
Query: 73 VSA-FAAFLMRAWEQIRNTIARDNLN-----VKIVATHSGFSDFLDGSSHQCLEDIALMR 126
+ F F+ ++ I IAR V S F + ++
Sbjct: 79 MEVQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGVHTPELHADNLEGILA 138
Query: 127 VLPNMKVVVPADAYATRALLYEIVEDHGPA----YMRLGRDFAPRVYEDGDEIKLGKANI 182
P +KVV+P+ Y + LL + + P +M+L R F V E+ I +GKAN+
Sbjct: 139 QSPGLKVVIPSGPYDAKGLLISSIRSNDPVVYLEHMKLYRSFREEVPEEEYTIDIGKANV 198
Query: 183 LRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVI 242
++G+DI + G MV +++ AE L+ G V+D+ TV+P+D T++ K +
Sbjct: 199 KKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQPIDVDTIVASVEKTGRAV 258
Query: 243 TLEEHTIFGGLGGAVAEALSEK 264
++E G+G AV LSE+
Sbjct: 259 VVQEAQRQAGVGAAVVAELSER 280
>pir||T44306 pyruvate dehydrogenase (lipoamide) (EC 1.2.4.1) E1 beta chain
[imported] - Haloferax volcanii
>gi|4958990|gb|AAD34203.1|AF068743_2 (AF068743) pyruvate
decarboxylase E1 beta subunit [Haloferax volcanii]
Length = 327
Score = 97.9 bits (240), Expect = 1e-19
Identities = 67/233 (28%), Positives = 108/233 (45%), Gaps = 16/233 (6%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQI--------RNTIARDN 95
DR I ++E ++GTA G+A G P+ F+ F+ ++QI T R
Sbjct: 53 DRVIDTPLAESGIVGTAIGMAAMGLKPVPEIQFSGFMYPGFDQIVSHMGRFRNRTRGRYT 112
Query: 96 LNVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGP 155
L + + A + G SH +++ +KVV+P+ Y T+ LL + D P
Sbjct: 113 LPMVLRAPYGG--GIRAPESHSESKEMFYAHEA-GLKVVIPSTPYDTKGLLISAIRDPDP 169
Query: 156 AYMR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGV 211
+ R F V ED + +G+A + R+G+D+ G M LE ENL+
Sbjct: 170 VIFMEPKLIYRAFRGEVPEDDYTVPIGEAAVRREGTDVSVFTFGAMTRPTLEAVENLEEE 229
Query: 212 GIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
GIDA V+D+ T+ PLD T++ +K + + E GGLG + + E+
Sbjct: 230 GIDAEVVDIRTISPLDRETIVESFKKTGRAVVVHEAPKNGGLGAEITATVQEE 282
>sp|P21874|ODPB_BACST PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT
>gi|98217|pir||S14230 pyruvate dehydrogenase (lipoamide)
(EC 1.2.4.1) E1-beta chain [validated] - Bacillus
stearothermophilus >gi|40042|emb|CAA37629.1| (X53560)
pyruvate dehydrogenase (lipoamide) [Bacillus
stearothermophilus]
Length = 325
Score = 94.8 bits (232), Expect = 1e-18
Identities = 71/240 (29%), Positives = 111/240 (45%), Gaps = 30/240 (12%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIARD--------N 95
DR ++E + G A GLA+ G P+ F F+ + I +AR +
Sbjct: 51 DRVFDTPLAESGIGGLAIGLALQGFRPVPEIQFFGFVYEVMDSICGQMARIRYRTGGRYH 110
Query: 96 LNVKIVATHSG-------FSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYE 148
+ + I + G SD L+G L+ P +KVV+P+ Y + LL
Sbjct: 111 MPITIRSPFGGGVHTPELHSDSLEG----------LVAQQPGLKVVIPSTPYDAKGLLIS 160
Query: 149 IVEDHGPA----YMRLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEV 204
+ D+ P +++L R F V E I +GKA+I R+G DI +A G MV +L+
Sbjct: 161 AIRDNDPVIFLEHLKLYRSFRQEVPEGEYTIPIGKADIKREGKDITIIAYGAMVHESLKA 220
Query: 205 AENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
A L+ GI A V+D+ TV+PLD T+I K I ++E G+ V ++E+
Sbjct: 221 AAELEKEGISAEVVDLRTVQPLDIETIIGSVEKTGRAIVVQEAQRQAGIAANVVAEINER 280
>pir||B70973 probable TRANSKETOLASE-LIKE PROTEIN - Mycobacterium tuberculosis
(strain H37RV) >gi|2661658|emb|CAA15764.1| (AL009198)
hypothetical protein Rv3379c [Mycobacterium
tuberculosis]
Length = 536
Score = 94.8 bits (232), Expect = 1e-18
Identities = 82/301 (27%), Positives = 135/301 (44%), Gaps = 18/301 (5%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAG 63
S+ + F + I DV+ + A ++ T ++P R GI+EQ ++ +AAG
Sbjct: 213 SWTDVFEDEIARIADDRSDVVGLTAAMRLPTGLGALSRRYPHRVFDSGIAEQHLLASAAG 272
Query: 64 LAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIA 123
LA AG P+V+ ++ FL RA++Q+ I L V +V +G + DG SH L D+A
Sbjct: 273 LAAAGTHPVVAVYSTFLHRAFDQLLFDIGLHRLPVTLVLDRAGVTG-PDGPSHHGLWDLA 331
Query: 124 LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRL--GRDFAPRVYEDGDEIKLGKAN 181
L+ +P ++ P DA R L + P +R G P E +G +
Sbjct: 332 LLACVPGFQIACPRDAPRLRQQLRTAIATAAPTAVRFPKGAPGEPITAEH----TIGGLD 387
Query: 182 ILRD-----GSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLAR 236
+L D+L VA G M ++ A L I V+D V P+ L LA
Sbjct: 388 VLHTPPPHWRPDVLLVAVGAMSRPCMDAARCLSEEQIGVTVVDPQWVWPISP-ALTELAG 446
Query: 237 KVNLVITLEEHTIFGGLGGAVAEALSEKMPR-RVIRIG--STTFGRSSRDYLSLLDRYGL 293
+ + + +E+ G+G ++ + PR R +G +SRD+ +L +GL
Sbjct: 447 RHRITVCVEDAIADVGIGAHLSHHIGRTHPRTRTYTLGLPPAYIPHASRDH--ILSSHGL 504
Query: 294 S 294
+
Sbjct: 505 T 505
>sp|P37941|ODBB_BACSU 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT (BRANCHED-CHAIN
ALPHA-KETO ACID DEHYDROGENASE COMPONENT BETA CHAIN (E1))
(BCKDH E1-BETA) >gi|421505|pir||S32487
3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC
1.2.4.4) E1 beta chain - Bacillus subtilis
>gi|7431580|pir||D69593 3-methyl-2-oxobutanoate
dehydrogenase (lipoamide) (EC 1.2.4.4) E1 beta chain
bfmBAB - Bacillus subtilis >gi|142612|gb|AAA22279.1|
(M97391) branched chain alpha-keto acid dehydrogenase
E1-beta [Bacillus subtilis] >gi|1303943|dbj|BAA12599.1|
(D84432) BfmBAB [Bacillus subtilis]
>gi|2634838|emb|CAB14335.1| (Z99116) branched-chain
alpha-keto acid dehydrogenase E1 (2-oxoisovalerate
dehydrogenase beta subunit) [Bacillus subtilis]
Length = 327
Score = 94.4 bits (231), Expect = 2e-18
Identities = 78/277 (28%), Positives = 125/277 (44%), Gaps = 15/277 (5%)
Query: 2 IESFRESFGRTLVEIGRKNKDVIVVDADVKNS----TKTVYFENQF-PDRFIQVGISEQD 56
+ S+ ++ + E ++ V V+ DV T QF +R + ++E
Sbjct: 3 VMSYIDAINLAMKEEMERDSRVFVLGEDVGRKGGVFKATAGLYEQFGEERVMDTPLAESA 62
Query: 57 MIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIA----RDNLNVKI-VATHSGFSDF 110
+ G G A+ G PI FA F+M A QI + A R N + + + +
Sbjct: 63 IAGVGIGAAMYGMRPIAEMQFADFIMPAVNQIISEAAKIRYRSNNDWSCPIVVRAPYGGG 122
Query: 111 LDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA----YMRLGRDFAP 166
+ G+ + A+ P +K+V+P+ Y + LL V D P + R R
Sbjct: 123 VHGALYHSQSVEAIFANQPGLKIVMPSTPYDAKGLLKAAVRDEDPVLFFEHKRAYRLIKG 182
Query: 167 RVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPL 226
V D + +GKA++ R+G DI + G+ V AL+ AE L+ GI A V+D+ TV PL
Sbjct: 183 EVPADDYVLPIGKADVKREGDDITVITYGLCVHFALQAAERLEKDGISAHVVDLRTVYPL 242
Query: 227 DERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSE 263
D+ +I A K V+ + E T G + VA +SE
Sbjct: 243 DKEAIIEAASKTGKVLLVTEDTKEGSIMSEVAAIISE 279
>sp|P21882|ODPB_BACSU PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT (S COMPLEX, 36 KD
SUBUNIT) >gi|98441|pir||C36718 pyruvate dehydrogenase
(lipoamide) (EC 1.2.4.1) E1 beta chain precursor pdhB -
Bacillus subtilis >gi|143378|gb|AAA62682.1| (M57435)
pyruvate decarboxylase (E-1) beta subunit [Bacillus
subtilis] >gi|2633830|emb|CAB13332.1| (Z99111) pyruvate
dehydrogenase (E1 beta subunit) [Bacillus subtilis]
>gi|3282143|gb|AAC24933.1| (AF012285) pyruvate
decarboxylase E-1 beta subunit [Bacillus subtilis]
Length = 325
Score = 92.8 bits (227), Expect = 5e-18
Identities = 64/230 (27%), Positives = 106/230 (45%), Gaps = 10/230 (4%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIARDNLN-----V 98
DR ++E + G A GL + G P++ F F+ + + +AR
Sbjct: 51 DRVFDTPLAESGIGGLALGLGLNGFRPVMEIQFFGFVYEVMDSVSGQMARMRYRSGGRWT 110
Query: 99 KIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA-- 156
V S F + L+ P +KVV+P+ Y + LL + D+ P
Sbjct: 111 SPVTIRSPFGGGVHTPELHADSLEGLVAQQPGIKVVIPSTPYDAKGLLISAIRDNDPVVF 170
Query: 157 --YMRLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGID 214
+M+L R F V E+ I+LGKA++ R+G+D+ + G MV +L+ A+ L+ GI
Sbjct: 171 LEHMKLYRSFRQEVPEEEYTIELGKADVKREGTDLSIITYGAMVHESLKAADELEKDGIS 230
Query: 215 AGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
A V+D+ TV PLD T+I K I ++E G+ V ++++
Sbjct: 231 AEVVDLRTVSPLDIDTIIASVEKTGRAIVVQEAQKQAGIAANVVAEINDR 280
>pir||A83128 acetoin catabolism protein AcoB PA4151 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950357|gb|AAG07538.1|AE004831_10 (AE004831) acetoin
catabolism protein AcoB [Pseudomonas aeruginosa]
Length = 339
Score = 91.3 bits (223), Expect = 1e-17
Identities = 74/288 (25%), Positives = 124/288 (42%), Gaps = 31/288 (10%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDAD----------------VKNSTKTVYFENQFPDRF 47
S++++ L + R++ V ++ D V TK +Y +QFP R
Sbjct: 6 SYQQAINEALAQEMRRDPSVFIMGEDNAGGAGAPGEDDAWGGVLGVTKGLY--HQFPGRV 63
Query: 48 IQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIARDN-------LNVK 99
+ +SE +G A G A G P+ F F +QI N A+ +
Sbjct: 64 LDTPLSEIGYVGAAVGAATRGMRPVCELMFVDFAGCCLDQILNQAAKFRYMFGGKAVTPL 123
Query: 100 IVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYM- 158
++ T G Q L +L +P +KVV P+ Y + LL + + D+ P
Sbjct: 124 VIRTMVGAGLRAAAQHSQMLT--SLWTHIPGLKVVCPSSPYDAKGLLVQAIRDNDPVIFC 181
Query: 159 --RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAG 216
+L V E+ + G+AN LRDG D+ V G MV +AL+ A +L GI
Sbjct: 182 EHKLLYSMQGEVPEELYSVPFGEANFLRDGDDVTLVTYGRMVHLALDAAASLARQGISCE 241
Query: 217 VLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
VLD+ + PLDE +++ K ++ ++E + +A ++E+
Sbjct: 242 VLDLRSTSPLDEDSILESVEKTGRLVVVDEANPRCSMATDIAALVAER 289
>sp|Q9ZDR3|ODPB_RICPR PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT
>gi|7431571|pir||B71681 pyruvate dehydrogenase E1
component, beta chain precursor (pdhB) RP262 -
Rickettsia prowazekii >gi|3860824|emb|CAA14724.1|
(AJ235271) PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA
SUBUNIT PRECURSOR (pdhB) [Rickettsia prowazekii]
Length = 326
Score = 90.1 bits (220), Expect = 3e-17
Identities = 67/231 (29%), Positives = 109/231 (47%), Gaps = 15/231 (6%)
Query: 46 RFIQVGISEQDMIGTAAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDNL----NVKI 100
R I I+E G A G A AG PIV F M+A++ I N+ A+ + VK
Sbjct: 51 RVIDTPITEYGFAGLAVGAAFAGLRPIVEFMTFNFAMQAFDHIVNSAAKTHYMSGGQVKC 110
Query: 101 VATHSGFSDFLDGSSHQCLEDI-ALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY-- 157
G + + Q ++ A +P +KVV P A + L+ + D P
Sbjct: 111 PIVFRGPNGAASRVAAQHSQNYTACYSHIPGLKVVAPYSAEDHKGLMLTAIRDDNPVIFL 170
Query: 158 ---MRLGRDF-APRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGI 213
+ G F P + E I KA IL++GS++ V + V +AL+V L+ I
Sbjct: 171 ENEILYGHSFDVPDIIEP---IPFSKAKILKEGSNVTIVTFSIQVKLALDVVNILQNDNI 227
Query: 214 DAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
D ++D+ T+KPLD ++I +K N ++ +EE F G+G ++A + ++
Sbjct: 228 DCELIDLRTIKPLDTDSIIESVKKTNRLVIVEEGWFFAGVGASIASIVMKE 278
>sp|O34591|ACOB_BACSU ACETOIN:2,6-DICHLOROPHENOLINDOPHENOL OXIDOREDUCTASE BETA SUBUNIT
(ACETOIN:DCPIP OXIDOREDUCTASE-BETA) (AO:DCPIP OR)
(TPP-DEPENDENT ACETOIN DEHYDROGENASE E1 BETA-SUBUNIT)
>gi|7431575|pir||E69581 acetoin dehydrogenase E1
component (TPP-dependent beta subunit) acoB - Bacillus
subtilis >gi|2245638|gb|AAC05583.1| (AF006075)
TPP-dependent acetoin dehydrogenase, E1 beta-subunit
[Bacillus subtilis] >gi|2633131|emb|CAB12636.1| (Z99108)
acetoin dehydrogenase E1 component (TPP-dependent beta
subunit) [Bacillus subtilis] >gi|2780394|dbj|BAA24295.1|
(D78509) YfjJ [Bacillus subtilis]
Length = 342
Score = 88.9 bits (217), Expect = 7e-17
Identities = 69/230 (30%), Positives = 106/230 (46%), Gaps = 13/230 (5%)
Query: 46 RFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLNV 98
R + ISE +G A A G PI F F+ ++Q+ N A+ V
Sbjct: 65 RVLDTPISEAGYMGAAMAAASTGLRPIAELMFNDFIGTCFDQVINQGAKFRYMFGGKAQV 124
Query: 99 KIVATHSGFSDFLDGSSH-QCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
I + + F + H Q L L +P +K VVP++ Y + LL +ED+ P +
Sbjct: 125 PITVRTTYGAGFRAAAQHSQSL--YGLFTSIPGLKTVVPSNPYDAKGLLLAAIEDNDPVF 182
Query: 158 M---RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGID 214
+ + V ED I LGKA+I R+G+D+ A G V+ ALE A L GI+
Sbjct: 183 FFEDKTSYNMKGEVPEDYYTIPLGKADIKREGNDVTLFAVGKQVNTALEAAAQLSERGIE 242
Query: 215 AGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
A VLD ++ PLDE + K N +I ++E + +A +++K
Sbjct: 243 AEVLDPRSLSPLDEDAIFTSLEKTNRLIIIDEANPRCSIATDIAALVADK 292
>dbj|BAB06481.1| (AP001516) branched-chain alpha-keto acid dehydrogenase E1
[Bacillus halodurans]
Length = 327
Score = 88.9 bits (217), Expect = 7e-17
Identities = 74/279 (26%), Positives = 129/279 (45%), Gaps = 19/279 (6%)
Query: 2 IESFRESFGRTLVEIGRKNKDVIVVDADVK------NSTKTVYFENQFPD-RFIQVGISE 54
+ S+ E+ L E ++++V V+ DV +T +Y QF + R + ++E
Sbjct: 3 VMSYIEAVTLALKEEMERDENVFVLGEDVGARGGVFRATNGLY--EQFGEARVLDTPLAE 60
Query: 55 QDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIA----RDNLNVKIVAT-HSGFS 108
+ G G A+ G P+ FA F+M A QI + A R N + + T + +
Sbjct: 61 SAIAGVGIGAAMYGMRPVAEIQFADFIMPAVNQIVSEAAKIRYRSNNDWQCPITIRAPYG 120
Query: 109 DFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA----YMRLGRDF 164
+ G+ + A+ P +K+V+P+ Y + LL + P + R R
Sbjct: 121 GGIHGALYHSQSVEAMFANTPGLKIVMPSTPYDVKGLLKAAIRSDDPVLFFEHKRAYRLI 180
Query: 165 APRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVK 224
V E+ + +GKA++ R+G D+ + G+ V AL+ AE L+ GI +LD+ TV
Sbjct: 181 KGEVPENDYTLPIGKADVKREGDDVTVITYGLAVHFALQAAERLEKDGISTHILDLRTVY 240
Query: 225 PLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSE 263
PLD+ +I A K ++ + E G + VA ++E
Sbjct: 241 PLDKDAIIEAASKTGKILLVTEDNKEGSIMSEVAAIIAE 279
>gb|AAG38098.1|AF299324_2 (AF299324) pyruvate dehydrogenase beta subunit [Azorhizobium
caulinodans]
Length = 466
Score = 88.5 bits (216), Expect = 9e-17
Identities = 75/287 (26%), Positives = 118/287 (40%), Gaps = 41/287 (14%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRF-----IQVGISEQDMIGT 60
RE+ + E R++ DV V+ +V F + I+E G
Sbjct: 147 REALRDAMAEEMRRDGDVFVMGEEVAEYQGAYKITQGLLQEFGAKRVVDTPITEHGFAGM 206
Query: 61 AAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIAR------------------DNLNVKIV 101
G A+AG PI+ F M+A +QI N+ A+ + ++
Sbjct: 207 GVGAAMAGLKPIIEFMTFNFAMQAIDQIINSAAKTLYMSGGQVQCSVVFRGPNGAAARVA 266
Query: 102 ATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLG 161
A HS D+ SH +P +KVV P A + LL + D P
Sbjct: 267 AQHS--QDYAAWYSH-----------IPGLKVVAPYTAADAKGLLKAAIRDPNPVIFLEN 313
Query: 162 RDFAPRVYE----DGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGV 217
+E D + +GKA I R G D+ V+ + ++ L+ AE L GI+A V
Sbjct: 314 EILYGHSFEVPKLDDYVLPIGKARIARAGKDVTLVSWSIGMTYTLKAAEELAKQGIEAEV 373
Query: 218 LDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+D+ T++P+D T+I +K +T+EE G+G +A L EK
Sbjct: 374 IDLRTIRPMDVPTIIESVKKTGRCVTVEEGWPQSGVGSEIAAQLMEK 420
>sp|P27746|ACOB_ALCEU ACETOIN:2,6-DICHLOROPHENOLINDOPHENOL OXIDOREDUCTASE BETA SUBUNIT
(ACETOIN:DCPIP OXIDOREDUCTASE-BETA) (AO:DCPIP OR)
(TPP-DEPENDENT ACETOIN DEHYDROGENASE E1 BETA-SUBUNIT)
>gi|95463|pir||C42462
acetoin-2,6-dichlorophenolindophenol oxidoreductase (EC
1.-.-.-) beta chain - Alcaligenes eutrophus (strain H16)
>gi|141895|gb|AAA21949.1| (M66060) acetoin:DCPIP
oxidoreductase-beta [Ralstonia eutropha]
Length = 338
Score = 88.2 bits (215), Expect = 1e-16
Identities = 65/223 (29%), Positives = 103/223 (46%), Gaps = 13/223 (5%)
Query: 34 TKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIA 92
TK +Y ++ DR + +SE +G A G A G PI F F+ ++QI N A
Sbjct: 52 TKGLYAKHG--DRLLDTPLSESAYVGAAIGAAACGMRPIAELMFIDFMGVCFDQIFNQAA 109
Query: 93 R------DNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALL 146
+ +V + F + H + L +P +KVV P+ Y T+ LL
Sbjct: 110 KFRYMFGGKAETPVVIRAMVGAGFRAAAQHSQMLT-PLFTHIPGLKVVCPSTPYDTKGLL 168
Query: 147 YEIVEDHGPAYMRLGRDF---APRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALE 203
+ + D+ P ++ V E I G+ANI+RDG D+ V G+MV ALE
Sbjct: 169 IQAIRDNDPVIFCEHKNLYGLEGEVPEGAYAIPFGEANIVRDGKDVSIVTYGLMVHRALE 228
Query: 204 VAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEE 246
A L GI+A ++D+ T+ PLD T++ ++ ++E
Sbjct: 229 AAATLAKEGIEAEIVDLRTLSPLDMDTVLESVENTGRLVVVDE 271
>pir||I40791 acetoin dehydrogenase (TPP-dependent) (EC 1.-.-.-) beta chain -
Clostridium magnum >gi|472327|gb|AAA21745.1| (L31844)
TPP-dependent acetoin dehydrogenase beta-subunit
[Clostridium magnum]
Length = 333
Score = 87.8 bits (214), Expect = 2e-16
Identities = 74/260 (28%), Positives = 120/260 (45%), Gaps = 28/260 (10%)
Query: 41 NQFPDRFIQ-VGISEQDMIGTAAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIAR----- 93
++F D+ ++ ISE ++G A G A G PI F+ A + + N A+
Sbjct: 46 DEFGDKRVKDTPISEGAIVGCAIGAAATGLKPIAEIMMGDFVTVAMDMLVNQAAKLRYMF 105
Query: 94 -DNLNVKIVATHSGFSDFLDGSSH-QCLEDIALMRVLPNMKVVVPADAYATRALLYEIVE 151
+++ +V G + + H Q LE A + +P +KVV P+ LL ++
Sbjct: 106 GGKISLPMVVRLPGGAGLSAAAQHSQSLE--AWLTHVPGIKVVYPSTPADAAGLLLTAID 163
Query: 152 DHGPAYM-----------RLGRDFAPRVYEDGD--EIKLGKANILRDGSDILFVASGVMV 198
D P + D P + D I G A+I R+G+D+ +A+G MV
Sbjct: 164 DDNPVAFIEHKAMYGLKGEVPDDIKPIPFGVADIKPIPFGVADIKREGNDVTIIATGKMV 223
Query: 199 SVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVA 258
AL+ AE L GI+ V+D T+ PLD+ T+ N K V+ + E GG GG ++
Sbjct: 224 HEALKAAEQLSKDGIEVEVVDPRTLFPLDKETIFNSVNKTGKVVVVTEENKRGGYGGEIS 283
Query: 259 EALSEK----MPRRVIRIGS 274
+SE+ + V+RIG+
Sbjct: 284 AMISEEIFDSLDAPVVRIGA 303
>gb|AAC72192.1| (AF069908) pyruvate dehydrogenase E1 beta subunit isoform 1 [Zea
mays]
Length = 373
Score = 87.0 bits (212), Expect = 3e-16
Identities = 71/235 (30%), Positives = 107/235 (45%), Gaps = 17/235 (7%)
Query: 44 PDRFIQVGISEQDMIGTAAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDN------L 96
PDR + I+E G G A G PIV F M+A + I N+ A+ N +
Sbjct: 85 PDRVLDTPITEAGFTGIGVGAAYHGLRPIVEFMTFNFSMQAIDHIINSAAKSNYMSAGQI 144
Query: 97 NVKIVATHSGFSDFLDGSSH-QCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGP 155
+V IV + G+ H QC A +P +KV+ P A R LL + D P
Sbjct: 145 SVPIVFRGPNGAAAGVGAQHSQCYA--AWYAHVPGLKVLAPYSAEDARGLLKAAIRDPDP 202
Query: 156 AY-----MRLGRDF--APRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENL 208
+ G F + V + + +GKA I R G D+ A MV AL+ A+ L
Sbjct: 203 VVFLENELLYGESFPVSAEVLDSSFCLPIGKAKIERQGKDVTITAFSKMVGYALQAADIL 262
Query: 209 KGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSE 263
GI A V+++ +++PLD T+ RK N ++T+EE G+G + ++ E
Sbjct: 263 AKEGISAEVINLRSIRPLDRATINASVRKTNRLVTVEEGFPQHGIGAEICMSVVE 317
>gb|AAC72193.1| (AF069909) pyruvate dehydrogenase E1 beta subunit isoform 2 [Zea
mays]
Length = 374
Score = 86.6 bits (211), Expect = 3e-16
Identities = 69/236 (29%), Positives = 108/236 (45%), Gaps = 17/236 (7%)
Query: 44 PDRFIQVGISEQDMIGTAAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDN------L 96
PDR + I+E G G A G PI+ F M+A + I N+ A+ N +
Sbjct: 87 PDRVLDTPITEAGFTGIGVGAAYHGLRPIIEFMTFNFSMQAIDHIINSAAKSNYMSAGQI 146
Query: 97 NVKIVATHSGFSDFLDGSSH-QCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGP 155
+V IV + G+ H QC A +P +KV+ P + R LL + D P
Sbjct: 147 SVPIVFRGPNGAAAGVGAQHSQCYA--AWFAHVPGLKVLTPYSSEDARGLLKAAIRDPDP 204
Query: 156 AY-----MRLGRDF--APRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENL 208
+ G F + V + + +GKA I R+G D+ A MV AL+ AE L
Sbjct: 205 VIFLENELLYGESFPVSAEVLDSSFCLPIGKAKIEREGKDVTITAFSKMVGYALQAAEIL 264
Query: 209 KGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
GI A V+++ +++PLD + RK N ++T+EE G+G + ++ E+
Sbjct: 265 SKEGISAEVINLRSIRPLDRAAINASVRKTNRLVTVEEGFPQHGIGAEICMSVVEE 320
>gb|AAC01739.1| (AF040571) transketolase [Amycolatopsis mediterranei]
Length = 533
Score = 86.2 bits (210), Expect = 4e-16
Identities = 78/283 (27%), Positives = 125/283 (43%), Gaps = 14/283 (4%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+ R F T++E + V+++ AD+ +S + FPDR GI EQ MI A
Sbjct: 238 KQMRTVFAETVIESLATDPRVVMLTADI-SSWFFWEVKKDFPDRVHNFGIREQAMIDIAG 296
Query: 63 GLAIAGKIPIVSAFAAFLM-RAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLED 121
G A+AG+ P+V +A FL+ R +EQI+ + ++ +V+ + + D G +HQ D
Sbjct: 297 GFALAGQRPVVHTYAPFLVERPFEQIKIGLGHQDVGAVLVSVGASYDDPSWGRTHQAPGD 356
Query: 122 IALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKAN 181
+AL+ LP V VP LL + + Y+RL + R + + K
Sbjct: 357 VALLDTLPGWTVHVPGHEDEVAPLLSKAIAGDNRVYVRL----SERANSEAVPVS-EKFT 411
Query: 182 ILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLV 241
+LR G + +A G ++ L D VL T++P D L
Sbjct: 412 VLRRGKAGVVLAVGPVLDQVLAATAT-----ADVTVLYASTIRPFDHAGLREAVAAAAPN 466
Query: 242 ITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDY 284
+ L + + G V EAL + +P R+ G T R +R Y
Sbjct: 467 VVLVDPYLRGTSAFEVTEALGD-VPHRLRSFG-TWRDREARVY 507
>sp|Q38799|ODPB_ARATH PYRUVATE DEHYDROGENASE E1 COMPONENT BETA SUBUNIT, MITOCHONDRIAL
PRECURSOR (PDHE1-B) >gi|520478|gb|AAA52225.1| (U09137)
pyruvate dehydrogenase E1 beta subunit [Arabidopsis
thaliana] >gi|1090498|prf||2019230A pyruvate
dehydrogenase [Arabidopsis thaliana]
Length = 363
Score = 85.4 bits (208), Expect = 8e-16
Identities = 68/222 (30%), Positives = 101/222 (44%), Gaps = 17/222 (7%)
Query: 40 ENQFPDRFIQVGISEQDMIGTAAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDN--- 95
E P+R I+E G G A AG P+V F M+A + I N+ A+ N
Sbjct: 78 EKYGPERVYDTPITEAGFTGIGVGAAYAGLKPVVEFMTFNFSMQAIDHIINSAAKSNYMS 137
Query: 96 ---LNVKIVATHSGFSDFLDGSSH-QCLEDIALMRVLPNMKVVVPADAYATRALLYEIVE 151
+NV IV + G+ H QC A +P +KV+ P A R LL +
Sbjct: 138 AGQINVPIVFRGPNGAAAGVGAQHSQCYA--AWYASVPGLKVLAPYSAEDARGLLKAAIR 195
Query: 152 DHGPAY-----MRLGRDF--APRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEV 204
D P + G F + + + +GKA I R+G D+ V MV AL+
Sbjct: 196 DPDPVVFLENELLYGESFPISEEALDSSFCLPIGKAKIEREGKDVTIVTFSKMVGFALKA 255
Query: 205 AENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEE 246
AE L GI A V+++ +++PLD T+ RK + ++T+EE
Sbjct: 256 AEKLAEEGISAEVINLRSIRPLDRATINASVRKTSRLVTVEE 297
>sp|P52904|ODPB_PEA PYRUVATE DEHYDROGENASE E1 COMPONENT BETA SUBUNIT, MITOCHONDRIAL
PRECURSOR (PDHE1-B) >gi|7431574|pir||T06532 pyruvate
dehydrogenase (lipoamide) (EC 1.2.4.1) beta chain -
garden pea >gi|1336097|gb|AAB01223.1| (U56697) pyruvate
dehydrogenase E1beta [Pisum sativum]
Length = 359
Score = 85.4 bits (208), Expect = 8e-16
Identities = 68/238 (28%), Positives = 106/238 (43%), Gaps = 13/238 (5%)
Query: 40 ENQFPDRFIQVGISEQDMIGTAAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDNL-- 96
E P+R + I+E G G A G P+V F M+A + I N+ A+ N
Sbjct: 68 EKYGPERVLDTPITEAGFTGIGVGAAYYGLKPVVEFMTFNFSMQAIDHIINSAAKSNYMS 127
Query: 97 --NVKIVATHSGFSDFLDGSSHQCLEDIALMR-VLPNMKVVVPADAYATRALLYEIVEDH 153
+ + G + G Q A P +KV+VP A R LL + D
Sbjct: 128 AGQISVPIVFRGLNGDAAGVGAQHSHCYASWYGSCPGLKVLVPHSAEDARGLLKAAIRDP 187
Query: 154 GPAY-----MRLGRDF--APRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAE 206
P + G F + V + + +GKA I R+G D+ A MV AL+ AE
Sbjct: 188 DPVVFLENELLYGESFPVSAEVLDSSFWLPIGKAKIEREGKDVTITAFSKMVGFALKAAE 247
Query: 207 NLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
L+ GI A V+++ +++PLD T+ RK N ++T+EE G+G + ++ E+
Sbjct: 248 ILEKEGISAEVINLRSIRPLDRPTINASVRKTNRLVTVEEGFPQHGVGAEICTSVIEE 305
>dbj|BAA98121.1| (AB026637) pyruvate dehydrogenase E1 component beta subunit,
mitochondrial precursor (PDHE1-B) [Arabidopsis thaliana]
Length = 363
Score = 85.4 bits (208), Expect = 8e-16
Identities = 68/222 (30%), Positives = 101/222 (44%), Gaps = 17/222 (7%)
Query: 40 ENQFPDRFIQVGISEQDMIGTAAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDN--- 95
E P+R I+E G G A AG P+V F M+A + I N+ A+ N
Sbjct: 78 EKYGPERVYDTPITEAGFTGIGVGAAYAGLKPVVEFMTFNFSMQAIDHIINSAAKSNYMS 137
Query: 96 ---LNVKIVATHSGFSDFLDGSSH-QCLEDIALMRVLPNMKVVVPADAYATRALLYEIVE 151
+NV IV + G+ H QC A +P +KV+ P A R LL +
Sbjct: 138 AGQINVPIVFRGPNGAAAGVGAQHSQCYA--AWYASVPGLKVLAPYSAEDARGLLKAAIR 195
Query: 152 DHGPAY-----MRLGRDF--APRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEV 204
D P + G F + + + +GKA I R+G D+ V MV AL+
Sbjct: 196 DPDPVVFLENELLYGESFPISEEALDSSFCLPIGKAKIEREGKDVTIVTFSKMVGFALKA 255
Query: 205 AENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEE 246
AE L GI A V+++ +++PLD T+ RK + ++T+EE
Sbjct: 256 AEKLAEEGISAEVINLRSIRPLDRATINASVRKTSRLVTVEE 297
>gb|AAK41749.1| Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-2)
[Sulfolobus solfataricus]
Length = 324
Score = 84.7 bits (206), Expect = 1e-15
Identities = 72/276 (26%), Positives = 122/276 (44%), Gaps = 16/276 (5%)
Query: 4 SFRESFGRTLVEIGRKNKDVIVVDADVK------NSTKTVYFENQFPDRFIQVGISEQDM 57
+F E+ L + ++ VI++ D+ TK + E DR I ISE
Sbjct: 5 TFTEAINEALRQEMERDPSVILIGEDIGVYGGAFGVTKGL-IEKFGSDRVIDTPISEAGF 63
Query: 58 IGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR----DNLNVKIVAT-HSGFSDFL 111
IG A G A+AG P+V F F A +QI N +A+ +K+ T + +
Sbjct: 64 IGAAVGAALAGLRPVVELMFVDFFGVAMDQIYNQMAKLRYMSGGQLKVPLTLRAPIGAGI 123
Query: 112 DGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYM---RLGRDFAPRV 168
++ ++ +P +KVVVP+ + + LL + D P ++ V
Sbjct: 124 SAAAQHSQTLYSIFAHVPGLKVVVPSTPHDAKGLLISSIRDDNPVVFLEHKVLYGIKGEV 183
Query: 169 YEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDE 228
E+ I LGKA I R+G D+ + V +LE AE L I V+D+ ++ P D+
Sbjct: 184 PEEEYTIPLGKAEIRREGDDVTVIGIARTVWHSLEAAEQLSKESISVEVIDVRSIVPFDK 243
Query: 229 RTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
T+I +K V+ ++E G V+ ++++
Sbjct: 244 ETVIKSVKKTGRVVIVDEDYDRCGFASWVSSIIADE 279
>pir||T36497 probable branched-chain alpha keto acid dehydrogenase E1 beta chain
- Streptomyces coelicolor >gi|5457251|emb|CAB46939.1|
(AL096822) putative branched-chain alpha keto acid
dehydrogenase E1 beta subunit [Streptomyces coelicolor
A3(2)]
Length = 326
Score = 84.7 bits (206), Expect = 1e-15
Identities = 70/263 (26%), Positives = 121/263 (45%), Gaps = 17/263 (6%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIARDNLN----VK 99
DR I ++E ++GTA GLA+ G P+V F F+ A++QI +A+ + VK
Sbjct: 53 DRVIDTPLAESGIVGTAIGLALRGYRPVVEIQFDGFVFPAYDQIVTQLAKMHARSLGKVK 112
Query: 100 I-VATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA-Y 157
+ V + + H AL + +KVV P++A ++ + ++ P Y
Sbjct: 113 MPVVIRIPYGGGIGAVEHHSESPEALFAHVAGLKVVSPSNAADAYWMMQQAIQSDDPVIY 172
Query: 158 MRLGRDFAPRVYEDGDEIK--LGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDA 215
R + + D + I L A ++R+G+D+ A G MV + EVA+ G
Sbjct: 173 FEPKRRYWDKAEVDKEAIPGPLHTARVVREGTDLTLAAYGPMVKLCREVADAAAEEGRSL 232
Query: 216 GVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK----MPRRVIR 271
V+D+ ++ P+D T+ K +I + E +F G G +A ++E+ + V+R
Sbjct: 233 EVVDLRSISPVDFDTIQASVEKTRRLIVVHEAPVFLGSGAEIAARITERCFYHLEAPVLR 292
Query: 272 IGSTTF----GRSSRDYLSLLDR 290
+G R +YL LDR
Sbjct: 293 VGGYHAPYPPARLEEEYLPDLDR 315
>gb|AAF04588.1|AF190792_2 (AF190792) pyruvate dehydrogenase beta subunit [Sinorhizobium
meliloti]
Length = 460
Score = 84.7 bits (206), Expect = 1e-15
Identities = 72/276 (26%), Positives = 119/276 (43%), Gaps = 19/276 (6%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRF-----IQVGISEQDMIGT 60
RE+ + E R N+DV V+ +V F + I+E G
Sbjct: 141 REALRDAMAEEMRANEDVFVMGEEVAEYQGAYKVTQGLLQEFGARRVVDTPITEHGFAGV 200
Query: 61 AAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARD------NLNVKIVATH-SGFSDFLD 112
G A+ G PIV F M+A +QI N+ A+ + IV SG + +
Sbjct: 201 GVGAAMTGLRPIVEFMTFNFAMQAIDQIINSAAKTLYMSGGQMGAPIVFRGPSGAAARVA 260
Query: 113 GSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYE-- 170
QC A +P +KVV+P A + LL + D P + +E
Sbjct: 261 AQHSQCYA--AWYSHIPGLKVVMPYTAADAKGLLKAAIRDPNPVIFLENEILYGQSFEVP 318
Query: 171 --DGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDE 228
D + +GKA I R G D V+ G+ ++ A++ A L+ GID ++D+ T++P+D
Sbjct: 319 KLDDFVLPIGKARIHRTGKDATLVSFGIGMTYAIKAAAELEAQGIDVEIIDLRTIRPMDL 378
Query: 229 RTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
T+I +K ++T+EE +G +A + ++
Sbjct: 379 PTVIESVKKTGRLVTVEEGYPQSSVGTEIATRVMQQ 414
>sp|Q9R9N4|ODPB_RHIME PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT
Length = 460
Score = 84.7 bits (206), Expect = 1e-15
Identities = 72/276 (26%), Positives = 119/276 (43%), Gaps = 19/276 (6%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRF-----IQVGISEQDMIGT 60
RE+ + E R N+DV V+ +V F + I+E G
Sbjct: 141 REALRDAMAEEMRANEDVFVMGEEVAEYQGAYKVTQGLLQEFGARRVVDTPITEHGFAGV 200
Query: 61 AAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARD------NLNVKIVATH-SGFSDFLD 112
G A+ G PIV F M+A +QI N+ A+ + IV SG + +
Sbjct: 201 GVGAAMTGLRPIVEFMTFNFAMQAIDQIINSAAKTLYMSGGQMGAPIVFRGPSGAAARVA 260
Query: 113 GSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYE-- 170
QC A +P +KVV+P A + LL + D P + +E
Sbjct: 261 AQHSQCYA--AWYSHIPGLKVVMPYTAADAKGLLKAAIRDPNPVIFLENEILYGQSFEVP 318
Query: 171 --DGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDE 228
D + +GKA I R G D V+ G+ ++ A++ A L+ GID ++D+ T++P+D
Sbjct: 319 KLDDFVLPIGKARIHRTGKDATLVSFGIGMTYAIKAAAELEAQGIDVEIIDLRTIRPMDL 378
Query: 229 RTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
T+I +K ++T+EE +G +A + ++
Sbjct: 379 PTVIESVKKTGRLVTVEEGYPQSSVGTEIATRVMQQ 414
>gb|AAC72194.1| (AF069910) pyruvate dehydrogenase E1 beta subunit isoform 3 [Zea
mays]
Length = 374
Score = 84.3 bits (205), Expect = 2e-15
Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 15/235 (6%)
Query: 44 PDRFIQVGISEQDMIGTAAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDN------L 96
PDR + I+E G G A G P++ F M+A + I N+ A+ N +
Sbjct: 87 PDRVLDTPITEAGFTGIGVGAAYQGLRPVIEFMTFNFSMQAIDHIINSAAKSNYMSAGQI 146
Query: 97 NVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA 156
+V IV + G+ H + V P +KV+ P + R LL + D P
Sbjct: 147 SVPIVFRGPNGAAAGVGAQHSQCYAVWFAHV-PGLKVLTPYSSEDARGLLKAAIRDPDPV 205
Query: 157 Y-----MRLGRDF--APRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLK 209
+ G F + V + + +GKA I R G D+ A MV AL+ AE L
Sbjct: 206 IFLENELLYGESFPVSAEVLDSSFCLPIGKAKIERGGKDVTITAFSKMVGYALQAAEILS 265
Query: 210 GVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
GI A V+++ +++PLD + RK N ++T+EE G+G + ++ E+
Sbjct: 266 KEGISAEVINLRSIRPLDRAAINASVRKTNRLVTVEEGFPQHGIGAEICMSVVEE 320
>gi|4557353 branched chain keto acid dehydrogenase E1, beta polypeptide
precursor; Branched chain keto acid dehydrogenase E1,
beta polypeptide [Homo sapiens]
>gi|11417619|ref|XP_004136.1| branched chain keto acid
dehydrogenase E1, beta polypeptide precursor [Homo
sapiens] >gi|129034|sp|P21953|ODBB_HUMAN
2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT,
MITOCHONDRIAL PRECURSOR (BRANCHED-CHAIN ALPHA-KETO ACID
DEHYDROGENASE COMPONENT BETA CHAIN (E1)) (BCKDH E1-BETA)
>gi|105120|pir||A37157 3-methyl-2-oxobutanoate
dehydrogenase (lipoamide) (EC 1.2.4.4) E1-beta chain
precursor - human >gi|179362|gb|AAA51812.1| (M55575)
branched chain alpha-keto acid dehydrogenase E1-beta
subunit [Homo sapiens] >gi|219493|dbj|BAA14389.1|
(D90391) E-1-beta subunit [Homo sapiens]
>gi|1480477|gb|AAB16763.1| (U50708) branched chain
alpha-ketoacid dehydrogenase E1 beta subunit [Homo
sapiens]
Length = 392
Score = 83.9 bits (204), Expect = 2e-15
Identities = 62/232 (26%), Positives = 101/232 (42%), Gaps = 12/232 (5%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
DR + EQ ++G G+A+ G I FA ++ A++QI N A+ D N
Sbjct: 117 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 176
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ S + G+ + A P +KVV+P + + LL +ED P
Sbjct: 177 CGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 236
Query: 158 MR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLK-GVG 212
L R A V + I L +A ++++GSD+ VA G V V EVA K +G
Sbjct: 237 FFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLG 296
Query: 213 IDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+ V+D+ T+ P D T+ K ++ E + GG ++ + E+
Sbjct: 297 VSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE 348
>pdb|1DTW|B Chain B, Human Branched-Chain Alpha-Keto Acid Dehydrogenase
Length = 342
Score = 83.9 bits (204), Expect = 2e-15
Identities = 62/232 (26%), Positives = 101/232 (42%), Gaps = 12/232 (5%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
DR + EQ ++G G+A+ G I FA ++ A++QI N A+ D N
Sbjct: 67 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 126
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ S + G+ + A P +KVV+P + + LL +ED P
Sbjct: 127 CGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 186
Query: 158 MR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLK-GVG 212
L R A V + I L +A ++++GSD+ VA G V V EVA K +G
Sbjct: 187 FFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLG 246
Query: 213 IDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+ V+D+ T+ P D T+ K ++ E + GG ++ + E+
Sbjct: 247 VSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE 298
>emb|CAC12557.1| (AL445067) probable 3-methyl-2-oxobutanoate dehydrogenase chain
E1-beta [Thermoplasma acidophilum]
Length = 319
Score = 83.5 bits (203), Expect = 3e-15
Identities = 65/233 (27%), Positives = 105/233 (44%), Gaps = 17/233 (7%)
Query: 44 PDRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR-------DN 95
P R I +SE ++G A G+A+ G PI F F+ + +QI N +A+ D
Sbjct: 47 PQRVIDTPLSELGIVGMAIGMAVNGLKPIPEIQFQDFIYTSMDQIINQMAKIRYRSGGDY 106
Query: 96 LNVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGP 155
++ T G + G + A + VV P++ Y + LL +E P
Sbjct: 107 TVPLVLRTPVGGG--IKGGLYHSQSGEAYFAHTAGLTVVSPSNPYDAKGLLISAIESPDP 164
Query: 156 AYM----RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGV 211
RL R V ++ I L KAN+L+ G+D+ V G MV + VA K
Sbjct: 165 VIFLEPKRLYRAQKVEVPDEKYTIPLRKANVLKQGNDVTIVTYGSMVPTVMSVASKSK-- 222
Query: 212 GIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
D V+D+ T+ P+D T+I+ +K V+ + E G+G ++ +SE+
Sbjct: 223 -YDVEVIDLRTIAPMDRDTIISSVKKTGRVVIVHEAPRTLGVGAEISAMISER 274
>emb|CAA36685.1| (X52446) E1b-beta precursor (AA -31 to 342) [Homo sapiens]
Length = 373
Score = 83.1 bits (202), Expect = 4e-15
Identities = 62/232 (26%), Positives = 101/232 (42%), Gaps = 12/232 (5%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
DR + EQ ++G G+A+ G I FA ++ A++QI N A+ D N
Sbjct: 98 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 157
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ S + G+ + A P +KVV+P + + LL +ED P
Sbjct: 158 CGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 217
Query: 158 MR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLK-GVG 212
L R A V + I L +A ++++GSD+ VA G V V EVA K +G
Sbjct: 218 FFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLG 277
Query: 213 IDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+ V+D+ T+ P D T+ K ++ E + GG ++ + E+
Sbjct: 278 VSCEVIDLRTIIPWDVDTICKSVIKSGRLLISHEAPLTGGFASEISSTVQEE 329
>dbj|BAB05542.1| (AP001513) acetoin dehydrogenase E1 component (TPP-dependent beta
subunit) [Bacillus halodurans]
Length = 344
Score = 82.3 bits (200), Expect = 7e-15
Identities = 67/218 (30%), Positives = 96/218 (43%), Gaps = 23/218 (10%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
DR + ISE +G A A G PI F F+ +Q+ N A+
Sbjct: 64 DRVLDTPISEAGYVGAAMAAAATGLRPIAELMFNDFIGSCLDQVLNQGAKLRYMFGGKAQ 123
Query: 98 VKIVATHSGFSDFLDGSSH-QCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA 156
V + + F + H Q L A+ +P +KVVVP+ Y + LL +ED+ P
Sbjct: 124 VPVTIRTMHGAGFRAAAQHSQSL--YAMFTAMPGIKVVVPSTPYDAKGLLLSAIEDNDPV 181
Query: 157 --------YMRLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENL 208
Y +G V E I LGKA+I R G D+ VA G V AL A+ L
Sbjct: 182 IFFEDKTLYNTMGE-----VPEGHYTIPLGKADIKRRGDDLSVVAIGKQVHTALTAADLL 236
Query: 209 KGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEE 246
GI+ V+D ++ PLD T++ K N +I ++E
Sbjct: 237 AKKGIEVEVIDPRSLSPLDSETILTSVEKTNRLIVIDE 274
>pir||T46885 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4)
E1-beta chain [validated] - Streptomyces avermitilis
>gi|624140|gb|AAA66073.1| (U17169) E1-beta
branched-chain alpha keto acid dehydrogenase
[Streptomyces avermitilis]
Length = 334
Score = 81.5 bits (198), Expect = 1e-14
Identities = 59/235 (25%), Positives = 100/235 (42%), Gaps = 19/235 (8%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIARDNLNVK---- 99
DR ++E ++GTA G+A+ G P+V F AF A+EQ+ + +ARD +
Sbjct: 56 DRCTDTPLAEAGILGTAVGMAMYGLRPVVEMQFDAFAYPAFEQLISHVARDAQRTRGAMP 115
Query: 100 -IVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYM 158
+ + + G H A P + VV PA LL + P
Sbjct: 116 LPITIRVPYGGGIGGVEHHSDSSEAYYMATPGLHVVTPATVADAYGLLRAAIASDDPVVF 175
Query: 159 RLGRDFAPRVY---------EDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLK 209
+ R+Y E G +G+A + R G + G + V LE AE +
Sbjct: 176 LEPK----RLYWSKDSWNPDEPGTVEPIGRAVVRRSGRSATLITYGPSLPVCLEAAEAAR 231
Query: 210 GVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
G D V+D+ ++ P D+ T++ + + + + E +GG GG +A ++E+
Sbjct: 232 AEGWDLEVVDLRSLVPFDDETVVRVGARTGRAVVVHESGGYGGPGGEIAAGITER 286
>sp|P21839|ODBB_BOVIN 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, MITOCHONDRIAL
PRECURSOR (BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE
COMPONENT BETA CHAIN (E1)) (BCKDH E1-BETA)
>gi|108478|pir||A34267 3-methyl-2-oxobutanoate
dehydrogenase (lipoamide) (EC 1.2.4.4) E1 beta chain
precursor - bovine >gi|506803|gb|AAA30407.1| (M33323)
3-methyl-2-oxobutanoate dehydrogenase [Bos taurus]
Length = 392
Score = 81.1 bits (197), Expect = 1e-14
Identities = 61/232 (26%), Positives = 101/232 (43%), Gaps = 12/232 (5%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
DR + EQ ++G G+A+ G I FA ++ A++QI N A+ D N
Sbjct: 117 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 176
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ S + G+ + A P +KVVVP + + LL +ED P
Sbjct: 177 CGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCI 236
Query: 158 MR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEV-AENLKGVG 212
L R +V + I L +A ++++GSD+ VA G V V EV A + +G
Sbjct: 237 FFEPKILYRAAVEQVPVEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVDAMAQEKLG 296
Query: 213 IDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+ V+D+ T+ P D T+ K ++ E + GG ++ + E+
Sbjct: 297 VSCEVIDLRTILPWDVDTVCKSVIKTGRLLVSHEAPLTGGFASEISSTVQEE 348
>pir||C81683 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4)
alpha/beta E1 chain TC0618 [similarity] - Chlamydia
muridarum (strain Nigg) >gi|7190657|gb|AAF39449.1|
(AE002330) 2-oxoisovalerate dehydrogenase, E1 component,
alpha and beta subunit [Chlamydia muridarum]
Length = 678
Score = 81.1 bits (197), Expect = 1e-14
Identities = 69/285 (24%), Positives = 125/285 (43%), Gaps = 26/285 (9%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVY------FENQFPDRFIQVGISEQDMIG 59
R++ LVE ++ V+V DV + V+ E +R ++E +IG
Sbjct: 354 RDAITEALVEEMHRDPGVVVFGEDVAGNKGGVFGVTRTLTERFGRNRCFNTPLAEATIIG 413
Query: 60 TAAGLAIAGKIPIVSA--FAAFLMRAWEQIRNTIARDNLNVK-------IVATHSGFSDF 110
TA G+A G V+ FA ++ Q+ + A ++ T G +
Sbjct: 414 TAIGMAFDGFHKPVAEIQFADYIWPGINQLFSEAASIYYRSAGEWEMPIVIRTPCG--GY 471
Query: 111 LDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA--------YMRLGR 162
+ G + A + P +KV P++A +ALL + D P Y R
Sbjct: 472 IQGGPYHSQNIEAFLAHCPGLKVAYPSNAADAKALLKAAIRDPNPVVFLEHKALYQRRAF 531
Query: 163 DFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHT 222
P V+ + GKA I+ G+D+ V+ G+ + +++EVA++L G+G+ V+D+ T
Sbjct: 532 STTP-VFSSDYVLPFGKARIVHSGTDLTIVSWGMSLVMSVEVAKDLLGLGVSVEVIDLRT 590
Query: 223 VKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEKMPR 267
+ P D T+ +K ++ + E + F G G + ++E+ R
Sbjct: 591 IVPCDFATVCESVKKTGKLLVVHEASEFCGFGSELVALVAERAYR 635
>gb|AAC13740.1| (U00985) acetoin:DCPIP oxidoreductase beta subunit [Klebsiella
pneumoniae]
Length = 339
Score = 80.8 bits (196), Expect = 2e-14
Identities = 72/292 (24%), Positives = 122/292 (41%), Gaps = 30/292 (10%)
Query: 2 IESFRESFGRTLVEIGRKNKDVIVVDADVK-----NSTKTVYFE-------------NQF 43
I+++RE+ L + +++ V+++ D++ N+ + E QF
Sbjct: 3 IKTYREAVKEALAQEMERDERVVLIGEDLRGGHGGNAPEEAKIEAFGGVLGVTKGLWTQF 62
Query: 44 -PDRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DN 95
DR I I+E +IG AAG A G P+ F F + + + N A+
Sbjct: 63 GSDRVIDTPITESAIIGMAAGAAATGLRPVAELMFMDFFGVSHDALYNQAAKFRYMFGGK 122
Query: 96 LNVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGP 155
+V + F + H + P +KVVVP+ Y + LL + + D P
Sbjct: 123 ARAPLVMRGMIGAGFSAAAQHS-QSPYNIFATTPGLKVVVPSTPYDVKGLLIQSIRDDDP 181
Query: 156 AYM---RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVG 212
++ D V ++ I LG AN R+G D+ +A MV A +VA+ L G
Sbjct: 182 VVFCEHKMLYDLKGEVPDEIYTIPLGVANYTREGEDVTIIALSAMVHKANQVADKLAREG 241
Query: 213 IDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
I V+D T+ PLDE ++ V+ ++E G VA ++ +
Sbjct: 242 ISVEVVDPRTISPLDEEGILESVASTGRVVIVDESAARFGFAHDVAALIASQ 293
>pir||S39807 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4) -
mouse
Length = 390
Score = 80.8 bits (196), Expect = 2e-14
Identities = 59/232 (25%), Positives = 102/232 (43%), Gaps = 12/232 (5%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
DR + EQ ++G G+A+ G I FA ++ A++QI N A+ D N
Sbjct: 115 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 174
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ + + G+ + A P +KVV+P + + LL +ED P
Sbjct: 175 CGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 234
Query: 158 MR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENL-KGVG 212
L R +V + +I L +A ++++GSD+ VA G V V EVA + +G
Sbjct: 235 FFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLG 294
Query: 213 IDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+ V+D+ T+ P D T+ K ++ E + GG ++ + E+
Sbjct: 295 VSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEE 346
>pir||H75295 transketolase - Deinococcus radiodurans (strain R1)
>gi|6460061|gb|AAF11802.1|AE002058_2 (AE002058)
transketolase [Deinococcus radiodurans]
Length = 666
Score = 80.4 bits (195), Expect = 3e-14
Identities = 86/323 (26%), Positives = 138/323 (42%), Gaps = 39/323 (12%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFEN------QFPDRFIQVGISEQDMIG 59
R + G + + + ++ AD+ STKT + R + G+ E M
Sbjct: 361 RNASGEVINALAKVLPGLMGGSADLSGSTKTTIKDGGEMEAGTMGGRNVLFGVREFGMSA 420
Query: 60 TAAGLAIAGKI-PIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQC 118
GL++ G + P+V F F R + A V V TH DG +HQ
Sbjct: 421 AGNGLSLYGGLHPMVGTFLVFADYLKPAFRLS-ALQMQPVTYVLTHDSIGLGEDGPTHQP 479
Query: 119 LEDIALMRVLPNMKVVVPADAYATRAL-LYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKL 177
++ +A++R +P V+ PADA T A L + D GP + L R P + + + +K
Sbjct: 480 VDQLAMLRAVPGAHVIRPADANETAAAWLMALEYDKGPTALALSRQDLPILPANIEGVKK 539
Query: 178 GKANILRD-------GSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDER- 229
G A +LRD G+ ++ +ASG V++AL AE L G+ A V+ M ++ ++
Sbjct: 540 G-AYVLRDVDGADGQGAQVILIASGSEVALALSSAERLAEEGVQARVVSMPCMEVFRQQE 598
Query: 230 ------TLINLARKVNLVITLEEHTIFGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRD 283
L ++V + + LGG V IG TTFG S+
Sbjct: 599 QSYRDSVLTPGVKRVAIEAASPQPWYEWTLGGPV--------------IGMTTFGASAPA 644
Query: 284 YLSLLDRYGLSVNKVYSKVLEVV 306
+ L +++G SV V V V+
Sbjct: 645 KV-LFEKFGFSVENVVKVVHSVL 666
>gb|AAA51410.1| (M81742) branched chain alpha-keto acid dehydrogenase E1-beta
subunit [Bos taurus]
Length = 369
Score = 79.6 bits (193), Expect = 4e-14
Identities = 60/232 (25%), Positives = 100/232 (42%), Gaps = 12/232 (5%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
DR + EQ ++G G+A+ G I FA ++ A++QI N A+ D N
Sbjct: 94 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 153
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ S + G+ + A P +KVVVP + + LL +ED P
Sbjct: 154 CGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCI 213
Query: 158 MR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKG-VG 212
L R +V + I L +A ++++GSD+ VA G V EVA + +G
Sbjct: 214 FFEPKILYRAAVEQVPVEPYNIPLSQAEVIQEGSDVTLVAWGTQVHEIREVAAMAQEKLG 273
Query: 213 IDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+ V+D+ T+ P D T+ K ++ E + GG ++ + E+
Sbjct: 274 VSCEVIDLRTILPWDVDTVCKSVIKTGRLLVSHEAPLTGGFASEISSTVQEQ 325
>pir||S28950 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4)
chain E1-beta precursor - rat (fragment)
Length = 369
Score = 79.6 bits (193), Expect = 4e-14
Identities = 59/232 (25%), Positives = 101/232 (43%), Gaps = 12/232 (5%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
DR + EQ ++G G+A+ G I FA ++ A++QI N A+ D N
Sbjct: 94 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 153
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ + + G+ + A P +KVV+P + + LL +ED P
Sbjct: 154 CGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 213
Query: 158 MR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENL-KGVG 212
L R +V + I L +A ++++GSD+ VA G V V EVA + +G
Sbjct: 214 FFEPKILYRAAVEQVPVEPYRIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLG 273
Query: 213 IDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+ V+D+ T+ P D T+ K ++ E + GG ++ + E+
Sbjct: 274 VSCEVIDLTTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEE 325
>pir||C36953 acetoin[2,6-dichlorophenolindophenol] oxidoreductase (EC 1.-.-.-)
beta chain - Pelobacter carbinolicus
>gi|434024|gb|AAA18916.1| (U01100) acetoin:DCPIP
oxidoreductase beta subunit [Pelobacter carbinolicus]
>gi|1220436|gb|AAA91876.1| (L24124) acetoin:DCPIP
oxidoreductase beta subunit [Pelobacter carbinolicus]
Length = 337
Score = 79.2 bits (192), Expect = 6e-14
Identities = 62/287 (21%), Positives = 118/287 (40%), Gaps = 26/287 (9%)
Query: 5 FRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQ-----------------FPDRF 47
F+++ + +++ V+++ DV TV + + FPDR
Sbjct: 7 FKDALNEAMRLEMERDESVVLIGLDVAGGAGTVTLDKERDSWGGVLGVSKGLYPLFPDRI 66
Query: 48 IQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR-----DNLNVKIV 101
I ISE IG A G + G I F+ F+ ++Q+ N A+ V V
Sbjct: 67 IDTPISESAYIGAAVGASACGLRAIGELMFSDFMGVCFDQLYNQAAKFRYMFGGKAVTPV 126
Query: 102 ATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYM--- 158
+ ++ ++ +P +K ++P++ Y + LL + D P
Sbjct: 127 TIRTMIGAGFSAAAQHSQSPYSMFAHVPGLKCIIPSNPYDAKGLLAASIADDDPCVFFEH 186
Query: 159 RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVL 218
+ V E+ I LGKAN++++G D+ VA MV A + A+ L GI+ ++
Sbjct: 187 KALYTMKGEVPEEHYTIPLGKANVVQEGKDVTIVALARMVQFAEKAAKKLAKDGIECTII 246
Query: 219 DMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEKM 265
D T+ P+D + + K ++ ++E G+ + S+ +
Sbjct: 247 DPRTISPMDWDAIYSSVEKTGRLVVVDESYDLCGVASDICGTCSQNV 293
>emb|CAA48166.1| (X68025) transketolase [Escherichia coli] >gi|882464|gb|AAA69102.1|
(U28377) transketolase [Escherichia coli]
Length = 664
Score = 78.8 bits (191), Expect = 8e-14
Identities = 80/320 (25%), Positives = 134/320 (41%), Gaps = 42/320 (13%)
Query: 7 ESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAI 66
E+FG L E + D+ + + + +K + +I G+ E M A G+++
Sbjct: 367 EAFGPLLPEFLGGSADLAPSNLTLWSGSKAI--NEDAAGNYIHYGVREFGMTAIANGISL 424
Query: 67 -AGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALM 125
G +P S F F+ A +R V +V TH DG +HQ +E +A +
Sbjct: 425 HGGFLPYTSTFLMFVEYARNAVRMAALMKQRQV-MVYTHDSIGLGEDGPTHQPVEQVASL 483
Query: 126 RVLPNMKVVVPADAYATR-ALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
RV PNM P D + A Y + GP + L R + +++ ANI R
Sbjct: 484 RVTPNMSTWRPCDQVESAVAWKYGVERQDGPTALILSRQNLAQQERTEEQL----ANIAR 539
Query: 185 DG---------SDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLIN-- 233
G +++F+A+G V +A+ E L G+ A V+ M + D++
Sbjct: 540 GGYVLKDCAGQPELIFIATGSEVELAVAAYEKLTAEGVKARVVSMSSTDAFDKQDAAYRE 599
Query: 234 --LARKVNLVITLEEHTI-----FGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLS 286
L + V + +E + GL GA+ +G TTFG S+ L
Sbjct: 600 SVLPKAVTARVAVEAGIADYWYKYVGLNGAI--------------VGMTTFGESAPAEL- 644
Query: 287 LLDRYGLSVNKVYSKVLEVV 306
L + +G +V+ V +K E++
Sbjct: 645 LFEEFGFTVDNVVAKAKELL 664
>gb|AAC38844.1| (AF013755) pyruvate dehydrogenase testis-specific beta subunit
[Ascaris suum]
Length = 357
Score = 78.8 bits (191), Expect = 8e-14
Identities = 67/234 (28%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARD------NLN 97
DR + I+E G A G A+AG PI F M+A +Q+ N+ A +N
Sbjct: 77 DRVLDTPITEMGFTGIAVGAAMAGMRPICEFMTYNFSMQAIDQVVNSAANTYYMSAGRVN 136
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRV-LPNMKVVVPADAYATRALLYEIVEDHGPA 156
V IV G + G + Q +D A P KV+ P + + + D P
Sbjct: 137 VPIV--FRGANGAGVGVAAQHSQDFAAWYAHCPVRKVISPYSSEDAKVFCKAAIRDDNPV 194
Query: 157 YMRLGRDFAPRVYEDGDE-------IKLGKANILRDGSDILFVASGVMVSVALEVAENLK 209
V+ DE + +G A I R G D VA + V A+E A LK
Sbjct: 195 VFMENEVLYSEVFPMSDEAMSPNFLLPIGVAKIERPGKDATIVAYSLGVKRAIEAATQLK 254
Query: 210 GVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSE 263
G GI+A V+++ T++PLD + K + V+T++ FG +G V + E
Sbjct: 255 GQGIEAEVINLRTLRPLDFEAIKKSVMKTHHVVTIDNGWPFGNIGAEVVAQVVE 308
>sp|P27302|TKT1_ECOLI TRANSKETOLASE 1 (TK 1) >gi|7427898|pir||XJECTK transketolase (EC
2.2.1.1) A - Escherichia coli >gi|2367177|gb|AAC75972.1|
(AE000376) transketolase 1 isozyme [Escherichia coli
K12]
Length = 663
Score = 78.8 bits (191), Expect = 8e-14
Identities = 80/320 (25%), Positives = 134/320 (41%), Gaps = 42/320 (13%)
Query: 7 ESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAI 66
E+FG L E + D+ + + + +K + +I G+ E M A G+++
Sbjct: 366 EAFGPLLPEFLGGSADLAPSNLTLWSGSKAI--NEDAAGNYIHYGVREFGMTAIANGISL 423
Query: 67 -AGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALM 125
G +P S F F+ A +R V +V TH DG +HQ +E +A +
Sbjct: 424 HGGFLPYTSTFLMFVEYARNAVRMAALMKQRQV-MVYTHDSIGLGEDGPTHQPVEQVASL 482
Query: 126 RVLPNMKVVVPADAYATR-ALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILR 184
RV PNM P D + A Y + GP + L R + +++ ANI R
Sbjct: 483 RVTPNMSTWRPCDQVESAVAWKYGVERQDGPTALILSRQNLAQQERTEEQL----ANIAR 538
Query: 185 DG---------SDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLIN-- 233
G +++F+A+G V +A+ E L G+ A V+ M + D++
Sbjct: 539 GGYVLKDCAGQPELIFIATGSEVELAVAAYEKLTAEGVKARVVSMSSTDAFDKQDAAYRE 598
Query: 234 --LARKVNLVITLEEHTI-----FGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRDYLS 286
L + V + +E + GL GA+ +G TTFG S+ L
Sbjct: 599 SVLPKAVTARVAVEAGIADYWYKYVGLNGAI--------------VGMTTFGESAPAEL- 643
Query: 287 LLDRYGLSVNKVYSKVLEVV 306
L + +G +V+ V +K E++
Sbjct: 644 LFEEFGFTVDNVVAKAKELL 663
>pir||H83219 probable pyruvate dehydrogenase E1 component, beta chain PA3416
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9949554|gb|AAG06804.1|AE004762_10 (AE004762)
probable pyruvate dehydrogenase E1 component, beta chain
[Pseudomonas aeruginosa]
Length = 333
Score = 78.4 bits (190), Expect = 1e-13
Identities = 62/232 (26%), Positives = 103/232 (43%), Gaps = 14/232 (6%)
Query: 46 RFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIARDNLNVK----- 99
R + ++E + G + G+A G P++ F F+ A EQ+ + +R +
Sbjct: 59 RVLDTPLAENMIAGLSIGMAAQGLKPVMEIQFMGFIYAAMEQLVSHASRLRNRTRGRLAC 118
Query: 100 --IVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
++ T G + H A+ +P ++V+VP+ LL ++D P
Sbjct: 119 PLVLRTPMGAG--IRAPEHHSEATEAMFAHIPGVRVLVPSSPARAYGLLLAAIDDPDPVI 176
Query: 158 M----RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGI 213
RL R + +D + L LR+G D+ V+ G V + AE L GI
Sbjct: 177 FLEPTRLYRMNPQPLADDARRLPLDSCFTLREGGDLTLVSWGASVHETQQAAERLAQRGI 236
Query: 214 DAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEKM 265
+A V+D+ +KPLD TL RK + + E GGLGG +A +L E++
Sbjct: 237 EAEVIDVACLKPLDLDTLEASVRKTGRCVIVHEAPKSGGLGGEIAASLYERV 288
>pir||H72128 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4)
alpha/beta E1 chain CP0743 [similarity] - Chlamydophila
pneumoniae (strains CWL029 and AR39)
>gi|4376286|gb|AAD18186.1| (AE001588) (pyruvate)
Oxoisovalerate Dehydrogenase Alpha & Beta Fusion
[Chlamydophila pneumoniae CWL029]
>gi|7189659|gb|AAF38548.1| (AE002233) 2-oxoisovalerate
dehydrogenase, E1 component, alpha and beta subunit
[Chlamydophila pneumoniae AR39]
>gi|8978408|dbj|BAA98245.1| (AP002545) (pyruvate)
oxoisovalerate dehydrogenase alpha and beta fusion
[Chlamydophila pneumoniae J138]
Length = 678
Score = 78.0 bits (189), Expect = 1e-13
Identities = 70/282 (24%), Positives = 119/282 (41%), Gaps = 26/282 (9%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVY------FENQFPDRFIQVGISEQDMIG 59
R++ LVE ++ VIV DV V+ E P R ++E +IG
Sbjct: 354 RDAISEALVEEMTRDSGVIVFGEDVAGDKGGVFGVTRNLTEKFGPQRCFNSPLAEATIIG 413
Query: 60 TAAGLAIAG--KIPIVSAFAAFLMRAWEQIRNTIARDNLNVK-------IVATHSGFSDF 110
TA G+A+ G K + FA ++ Q+ + + ++ SG +
Sbjct: 414 TAIGMALDGIHKPVVEIQFADYIWPGINQLFSEASSIYYRSAGEWEVPLVIRAPSG--GY 471
Query: 111 LDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA--------YMRLGR 162
+ G + + P +KV P++A +ALL + D P Y R
Sbjct: 472 IQGGPYHSQSIEGFLAHCPGIKVAYPSNAADAKALLKAAIRDPNPVVFLEHKALYQRRIF 531
Query: 163 DFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHT 222
P V+ + GKA I+ G D+ V+ G+ + ++LEVA+ L GI V+D+ T
Sbjct: 532 SACP-VFSHDYVLPFGKAAIVHPGKDLTIVSWGMPLVLSLEVAQELASRGISIEVIDLRT 590
Query: 223 VKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+ P D T++ K ++ + E + F G G + +SE+
Sbjct: 591 MVPCDFATVLKSLEKTGRLLVIHEASEFCGFGSELVATMSEQ 632
>sp|P35488|ODPB_ACHLA PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT
>gi|285174|pir||B42653 pyruvate dehydrogenase
(lipoamide) (EC 1.2.4.1) E1-beta chain - Acholeplasma
laidlawii >gi|141809|gb|AAA21908.1| (M81753) pyruvate
dehydrogenase E1-beta subunit [Acholeplasma laidlawii]
Length = 327
Score = 77.6 bits (188), Expect = 2e-13
Identities = 62/232 (26%), Positives = 104/232 (44%), Gaps = 16/232 (6%)
Query: 46 RFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLNV 98
R I+E ++G+A G+AI G PI F F+ + + AR V
Sbjct: 52 RVFDTPIAESAIVGSAVGMAINGLKPIAEIQFDGFIFPGYTDLVTHAARMRNRSRGQFTV 111
Query: 99 KIVAT--HSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA 156
+V H G L+ S + LE L +P +KVV P+ Y + LL + D P
Sbjct: 112 PMVLRLPHGGGIRALEHHS-EALE--VLFGSIPGLKVVTPSTPYDAKGLLLAAINDPDPV 168
Query: 157 YM----RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVG 212
R+ R V + EI +GKA +++ G+D+ VA G +V + + ++ G
Sbjct: 169 VFLEPKRIYRAGKQEVPAEMYEIPIGKAKVVKQGTDMTVVAWGSIVREVEKAVKLVEAEG 228
Query: 213 IDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
I ++D+ T+ P+DE T++N +K + + E G + ++EK
Sbjct: 229 ISVEIIDLRTISPIDEETILNSVKKTGKFMVVTEAVKSYGPAAELITMVNEK 280
>pir||T21454 hypothetical protein F27D4.5 - Caenorhabditis elegans
>gi|3876393|emb|CAB01970.1| (Z79695) Similarity to Human
2-oxoisovalerate dehydrogenase (SW:ODBB_HUMAN)~cDNA EST
yk543b8.3 comes from this gene~cDNA EST yk543b8.5 comes
from this gene [Caenorhabditis elegans]
Length = 366
Score = 77.3 bits (187), Expect = 2e-13
Identities = 63/237 (26%), Positives = 102/237 (42%), Gaps = 22/237 (9%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
DR + EQ + G G+A AG I F ++ A++Q+ N A+ + +
Sbjct: 91 DRVFNTPLCEQGIAGFGIGVAAAGATAIAEIQFGDYIFPAYDQLVNEAAKFRYRSGNQFD 150
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ + + G+ + A P +K+VVP + LL + D P
Sbjct: 151 CGKLTVRTTWGAVGHGALYHSQSPEANFTHTPGLKLVVPRGPVQAKGLLLSCIRDPNPCI 210
Query: 158 MRLGRDFAPRVY-----ED---GD-EIKLGKANILRDGSDILFVASGVMVSVALEVAENL 208
F P++ ED GD I LG+A +R G D+ VA G V VALE A+
Sbjct: 211 F-----FEPKILYRLASEDVPTGDYTIPLGQAETVRSGKDLTLVAWGTQVHVALEAAQLA 265
Query: 209 KG-VGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
K + D V+D+ T++P DE ++ +K +I E I G G +A + ++
Sbjct: 266 KEKLNADVEVIDLQTIQPWDEDHVVESVQKTGRLIVTHEAPISSGFGAEIASTVQKR 322
>gb|AAD55378.1|AF149712_6 (AF149712) TPP-dependent branched-chain alpha-keto acid
dehydrogenase, E1 beta subunit [Enterococcus faecalis]
Length = 328
Score = 77.3 bits (187), Expect = 2e-13
Identities = 42/139 (30%), Positives = 73/139 (52%), Gaps = 4/139 (2%)
Query: 129 PNMKVVVPADAYATRALLYEIVEDHGPA----YMRLGRDFAPRVYEDGDEIKLGKANILR 184
P ++VV P++ Y + ++ + P + RL R V D + + KAN++R
Sbjct: 142 PGLRVVTPSNPYDAKGMIKAAIRSDDPVIFYEHKRLYRLLKDEVPADDYIVPIDKANVVR 201
Query: 185 DGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITL 244
GSD+ ++ G+ + +AL AE L GIDA ++D+ ++ PLD TL+ A+K V+ +
Sbjct: 202 TGSDLTVISYGMTLQLALAAAEKLAAEGIDAEIVDVRSLYPLDRETLVAAAKKTGKVLLV 261
Query: 245 EEHTIFGGLGGAVAEALSE 263
E G + +A +SE
Sbjct: 262 TEDNKEGSVMSEIAAMISE 280
>gb|AAG20345.1| (AE005108) pyruvate dehydrogenase beta subunit; PdhB [Halobacterium
sp. NRC-1]
Length = 297
Score = 77.3 bits (187), Expect = 2e-13
Identities = 59/237 (24%), Positives = 103/237 (42%), Gaps = 14/237 (5%)
Query: 39 FENQFPDRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRN------TI 91
+E DR I ++E +IG+A G+A G P+ F+ F+ ++Q+ + T
Sbjct: 19 YEEFGDDRVIDTPLAESGIIGSAVGMAAYGLKPVPEIQFSGFMYPGFDQVVSHMSRLRTR 78
Query: 92 ARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVE 151
+R + +V + + H A +KV +P+ Y + +L +
Sbjct: 79 SRGRFTLPMVL-RAPMGGGIRAPEHHSESKEAFYAHEAGLKVAMPSTPYDAKGMLIASIR 137
Query: 152 DHGPAYM----RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAEN 207
D P ++ R F V +D E++LG A + +G D+ G M +E AEN
Sbjct: 138 DPDPVVFLEPKKIYRAFREDVPDDPYEVELGDAAVRTEGEDVSVFTWGAMTQPTVEAAEN 197
Query: 208 LKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
L ID V+D+ ++ P+D T+I +K + E GGLG + + E+
Sbjct: 198 LD--RIDVEVVDLRSLSPIDFDTIIESFKKTGRAAIVHEAPNTGGLGAEITATIQEE 252
>pir||G71526 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4)
alpha/beta E1 chain pdhA/B [similarity] - Chlamydia
trachomatis (serotype D, strain UW3/Cx)
>gi|3328760|gb|AAC67935.1| (AE001307) (pyruvate)
Oxoisovalerate Dehydrogenase Alpha and Beta Fusion
[Chlamydia trachomatis]
Length = 678
Score = 76.9 bits (186), Expect = 3e-13
Identities = 69/285 (24%), Positives = 125/285 (43%), Gaps = 26/285 (9%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVY-----FENQFPD-RFIQVGISEQDMIG 59
R++ LVE +++ V+V DV + V+ QF + R ++E +IG
Sbjct: 354 RDAITEALVEEMQRDPGVVVFGEDVAGNKGGVFGVTRTLTEQFGENRCFNTPLAEATIIG 413
Query: 60 TAAGLAIAGKIPIVSA--FAAFLMRAWEQIRNTIARDNLNVK-------IVATHSGFSDF 110
A G+A G V+ FA ++ Q+ + A ++ T G +
Sbjct: 414 AAVGMAFDGFYKPVAEIQFADYIWPGINQLFSEAASIYYRSAGEWEMPIVIRTPCG--GY 471
Query: 111 LDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPA--------YMRLGR 162
+ G + A + P +KVV P++A +ALL + D P Y R
Sbjct: 472 IQGGPYHSQNIEAFLAHCPGLKVVYPSNAADAKALLKAAIRDPNPVVFLEHKALYQRRLF 531
Query: 163 DFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHT 222
P V+ + G+A I+ G+D+ V+ G+ + +++EVA +L +GI V+D+ T
Sbjct: 532 STTP-VFSSDYVLPFGQARIVHPGTDLTIVSWGMSLVMSVEVARDLLELGISVEVIDLRT 590
Query: 223 VKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEKMPR 267
+ P D T+ +K ++ + E + F G G + ++E+ R
Sbjct: 591 IVPCDFATVCESVKKTGKLLVVHEASEFCGFGSELVALVAERAYR 635
>gb|AAF35281.1|AF145452_1 (AF145452) branched chain alpha-keto acid dehydrogenase E1 beta
subunit [Arabidopsis thaliana]
>gi|9280297|dbj|BAB01752.1| (AP000603) branched chain
alpha-keto acid dehydrogenase E1 beta subunit
[Arabidopsis thaliana]
Length = 358
Score = 76.9 bits (186), Expect = 3e-13
Identities = 57/230 (24%), Positives = 97/230 (41%), Gaps = 11/230 (4%)
Query: 46 RFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLNV 98
R + EQ ++G GLA G I FA ++ A++QI N A+ + N
Sbjct: 85 RVFNTPLCEQGIVGFGIGLAAMGNRVIAEIQFADYIFPAFDQIVNEAAKFRYRSGNQFNC 144
Query: 99 KIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYM 158
+ + + G + A +P +KVV+P + LL + D P
Sbjct: 145 GGLTIRAPYGAVGHGGHYHSQSPEAFFCHVPGIKVVIPRSPREAKGLLLSSIRDPNPVVF 204
Query: 159 R----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGID 214
L R V ED I L +A ++R+GSDI V G +++ + + + GI
Sbjct: 205 FEPKWLYRQAVEDVPEDDYMIPLSEAEVMREGSDITLVGWGAQLTIMEQACLDAENEGIS 264
Query: 215 AGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
++D+ T+ P D+ + RK ++ E + GG G +A + E+
Sbjct: 265 CELIDLKTLIPWDKEIVETSVRKTGRLLISHEAPVTGGFGAEIAATIVER 314
>gb|AAG21455.1|AC021894_15 (AC021894) branched chain alpha-keto acid dehydrogenase E1 beta
subunit protein copy 2 [Leishmania major]
Length = 366
Score = 76.9 bits (186), Expect = 3e-13
Identities = 62/240 (25%), Positives = 104/240 (42%), Gaps = 30/240 (12%)
Query: 44 PDRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNL 96
P + ++EQ ++G A G+A G PI FA ++ A++QI N A+ N
Sbjct: 93 PQKVFDSPLTEQGIVGFAVGMAAVGWHPIAEVQFADYIFPAFDQIVNEAAKYRFRTGSNF 152
Query: 97 NVKIVAT-------HSGF--SDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLY 147
+ ++ H G S ++G C P +K+V+P+ + LL
Sbjct: 153 HCGMLIRAPCSAVGHGGIYHSQSVEGYFTHC----------PGLKIVMPSSPSEAKGLLL 202
Query: 148 EIVEDHGPAYMR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALE 203
+ VE++ P L R V D + LGK IL +G D+ V G V VA +
Sbjct: 203 KCVEENDPCIFFEPKILYRSAVEEVNPDYYTLPLGKGRILVEGRDVTMVTYGSQVYVAAK 262
Query: 204 VAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSE 263
AE + GI ++D+ ++ P D + + + +K VI E G G + +++E
Sbjct: 263 AAEMARKEGISVELIDLRSLLPWDRQLVADSVKKTGKVIVTHEAPKTSGYGAELVSSITE 322
>sp|P35738|ODBB_RAT 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, MITOCHONDRIAL
PRECURSOR (BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE
COMPONENT BETA CHAIN (E1)) (BCKDH E1-BETA)
>gi|202808|gb|AAA73899.1| (M94040) branched chain
alpha-keto acid dehydrogenase E1-beta subunit [Rattus
norvegicus]
Length = 369
Score = 76.5 bits (185), Expect = 4e-13
Identities = 57/225 (25%), Positives = 99/225 (43%), Gaps = 12/225 (5%)
Query: 52 ISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLNVKIVATH 104
+ EQ ++G G+A+ G I FA ++ A++QI N A+ D N +
Sbjct: 101 LCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIR 160
Query: 105 SGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMR----L 160
+ + G+ + A P +KVV+P + + LL +ED P L
Sbjct: 161 APWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKIL 220
Query: 161 GRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENL-KGVGIDAGVLD 219
R +V + I L +A ++++GSD+ VA G V V EVA + +G+ V+D
Sbjct: 221 YRAAVEQVPVEPYRIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVID 280
Query: 220 MHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
+ T+ P D T+ K ++ E + GG ++ + E+
Sbjct: 281 LTTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEE 325
>gi|6319698 beta subunit of pyruvate dehydrogenase (E1 beta); Pdb1p
[Saccharomyces cerevisiae]
>gi|585609|sp|P32473|ODPB_YEAST PYRUVATE DEHYDROGENASE
E1 COMPONENT BETA SUBUNIT, MITOCHONDRIAL PRECURSOR
(PDHE1-B) >gi|625365|pir||S46097 pyruvate dehydrogenase
(lipoamide) (EC 1.2.4.1) beta chain precursor - yeast
(Saccharomyces cerevisiae) >gi|536613|emb|CAA85184.1|
(Z36090) ORF YBR221c [Saccharomyces cerevisiae]
Length = 366
Score = 75.3 bits (182), Expect = 9e-13
Identities = 74/276 (26%), Positives = 116/276 (41%), Gaps = 18/276 (6%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRF-----IQVGISEQDMIGT 60
RE+ + E ++ DV ++ +V DRF + I+E G
Sbjct: 42 REALNSAMAEELDRDDDVFLIGEEVAQYNGAYKVSKGLLDRFGERRVVDTPITEYGFTGL 101
Query: 61 AAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDNL----NVKIVATHSGFSDFLDGSS 115
A G A+ G PIV + F M+A + + N+ A+ + K G + G
Sbjct: 102 AVGAALKGLKPIVEFMSFNFSMQAIDHVVNSAAKTHYMSGGTQKCQMVFRGPNGAAVGVG 161
Query: 116 HQCLEDIA-LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY-----MRLGRDFAPRVY 169
Q +D + +P +KV+VP A R LL + D P + G F
Sbjct: 162 AQHSQDFSPWYGSIPGLKVLVPYSAEDARGLLKAAIRDPNPVVFLENELLYGESFEISEE 221
Query: 170 EDGDEIKLG-KANILRDGSDILFVASGVMVSVALEVAENL-KGVGIDAGVLDMHTVKPLD 227
E L KA I R+G+DI V V +LE AE L K G+ A V+++ +++PLD
Sbjct: 222 ALSPEFTLPYKAKIEREGTDISIVTYTRNVQFSLEAAEILQKKYGVSAEVINLRSIRPLD 281
Query: 228 ERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSE 263
+I +K N +IT+E G+G + + E
Sbjct: 282 TEAIIKTVKKTNHLITVESTFPSFGVGAEIVAQVME 317
>gi|11465732 pyruvate dehydrogenase E1 component, beta subunit [Porphyra
purpurea] >gi|1709455|sp|P51266|ODPB_PORPU PYRUVATE
DEHYDROGENASE E1 COMPONENT BETA SUBUNIT
>gi|2147993|pir||S73187 pyruvate dehydrogenase E1
component beta chain - red alga (Porphyra purpurea)
chloroplast >gi|1276732|gb|AAC08152.1| (U38804) pyruvate
dehydrogenase E1 component, beta subunit [Porphyra
purpurea]
Length = 331
Score = 75.3 bits (182), Expect = 9e-13
Identities = 69/244 (28%), Positives = 106/244 (43%), Gaps = 17/244 (6%)
Query: 46 RFIQVGISEQDMIGTAAGLAIAGKIPIVSAF-AAFLMRAWEQIRNTIAR------DNLNV 98
R + I+E G A G AI G PIV +FL+ A+ QI N N +
Sbjct: 52 RVLDTPIAENSFTGMAIGAAITGLRPIVEGMNMSFLLLAFNQISNNAGMLRYTSGGNFTL 111
Query: 99 KIVATHSGFSDFLDGSSH-QCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+V G G+ H Q LE A + +P +K+V + Y + LL + D+ P
Sbjct: 112 PLVIRGPGGVGRQLGAEHSQRLE--AYFQAIPGLKIVACSTPYNAKGLLKSAIRDNNPVV 169
Query: 158 MR---LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGID 214
L + + ED I L KA ++R G DI + M E L G D
Sbjct: 170 FFEHVLLYNLQEEIPEDEYLIPLDKAEVVRKGKDITILTYSRMRHHVTEALPLLLNDGYD 229
Query: 215 AGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLG----GAVAEALSEKMPRRVI 270
VLD+ ++KPLD ++ +K + V+ +EE G+G + E L +++ V+
Sbjct: 230 PEVLDLISLKPLDIDSISVSVKKTHRVLIVEECMKTAGIGAELIAQINEHLFDELDAPVV 289
Query: 271 RIGS 274
R+ S
Sbjct: 290 RLSS 293
>pir||T51835 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4) beta
chain [imported] - Arabidopsis thaliana
>gi|3746568|gb|AAC64005.1| (AF061638) branched-chain
alpha-keto acid decarboxylase E1 beta subunit
[Arabidopsis thaliana]
Length = 352
Score = 75.3 bits (182), Expect = 9e-13
Identities = 56/231 (24%), Positives = 99/231 (42%), Gaps = 11/231 (4%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
+R + EQ ++G GLA G IV FA ++ A++QI N A+ + N
Sbjct: 78 NRVFNTPLCEQGIVGFGIGLAAMGNRAIVEIQFADYIYPAFDQIVNEAAKFRYRSGNQFN 137
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ + + G + A +P +KVV+P + LL + D P
Sbjct: 138 CGGLTIRAPYGAVGHGGHYHSQSPEAFFCHVPGIKVVIPRSPREAKGLLLSCIRDPNPVV 197
Query: 158 MR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGI 213
L R V E I L +A ++R+G+DI V G ++V + + + GI
Sbjct: 198 FFEPKWLYRQAVEEVPEHDYMIPLSEAEVIREGNDITLVGWGAQLTVMEQACLDAEKEGI 257
Query: 214 DAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
++D+ T+ P D+ T+ +K ++ E + GG G ++ + E+
Sbjct: 258 SCELIDLKTLLPWDKETVEASVKKTGRLLISHEAPVTGGFGAEISATILER 308
>gb|AAD10651.1| (AC005223) branched-chain alpha-keto acid decarboxylase E1 beta
subunit [Arabidopsis thaliana]
Length = 352
Score = 75.3 bits (182), Expect = 9e-13
Identities = 56/231 (24%), Positives = 99/231 (42%), Gaps = 11/231 (4%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR------DNLN 97
+R + EQ ++G GLA G IV FA ++ A++QI N A+ + N
Sbjct: 78 NRVFNTPLCEQGIVGFGIGLAAMGNRAIVEIQFADYIYPAFDQIVNEAAKFRYRSGNQFN 137
Query: 98 VKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY 157
+ + + G + A +P +KVV+P + LL + D P
Sbjct: 138 CGGLTIRAPYGAVGHGGHYHSQSPEAFFCHVPGIKVVIPRSPREAKGLLLSCIRDPNPVV 197
Query: 158 MR----LGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGI 213
L R V E I L +A ++R+G+DI V G ++V + + + GI
Sbjct: 198 FFEPKWLYRQAVEEVPEHDYMIPLSEAEVIREGNDITLVGWGAQLTVMEQACLDAEKEGI 257
Query: 214 DAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
++D+ T+ P D+ T+ +K ++ E + GG G ++ + E+
Sbjct: 258 SCELIDLKTLLPWDKETVEASVKKTGRLLISHEAPVTGGFGAEISATILER 308
>gb|AAA34583.1| (M98476) pyruvate dehydrogenase E1-beta subunit [Saccharomyces
cerevisiae]
Length = 366
Score = 75.3 bits (182), Expect = 9e-13
Identities = 74/276 (26%), Positives = 116/276 (41%), Gaps = 18/276 (6%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRF-----IQVGISEQDMIGT 60
RE+ + E ++ DV ++ +V DRF + I+E G
Sbjct: 42 REALNSAMAEELDRDDDVFLIGEEVAQYNGAYKVSKGLLDRFGERRVVDTPITEYGFTGL 101
Query: 61 AAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDNL----NVKIVATHSGFSDFLDGSS 115
A G A+ G PIV + F M+A + + N+ A+ + K G + G
Sbjct: 102 AVGAALKGLKPIVEFMSFNFSMQAIDHVVNSAAKTHYMSGGTQKCQMVFRGPNGAAVGLG 161
Query: 116 HQCLEDIA-LMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY-----MRLGRDFAPRVY 169
Q +D + +P +KV+VP A R LL + D P + G F
Sbjct: 162 AQHSQDFSPWYGSIPGLKVLVPYSAEDARGLLKAAIRDPNPVVFLENELLYGESFEISEE 221
Query: 170 EDGDEIKLG-KANILRDGSDILFVASGVMVSVALEVAENL-KGVGIDAGVLDMHTVKPLD 227
E L KA I R+G+DI V V +LE AE L K G+ A V+++ +++PLD
Sbjct: 222 ALSPEFTLPYKAKIEREGTDISIVTYTRNVQFSLEAAEILQKKYGVSAEVINLRSIRPLD 281
Query: 228 ERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSE 263
+I +K N +IT+E G+G + + E
Sbjct: 282 TEAIIKTVKKTNHLITVESTFPSFGVGAEIVAQVME 317
>pir||T36511 probable branched-chain alpha keto acid dehydrogenase E1 beta chain
- Streptomyces coelicolor >gi|5457265|emb|CAB46953.1|
(AL096822) putative branched-chain alpha keto acid
dehydrogenase E1 beta subunit [Streptomyces coelicolor
A3(2)]
Length = 334
Score = 74.5 bits (180), Expect = 1e-12
Identities = 60/233 (25%), Positives = 104/233 (43%), Gaps = 15/233 (6%)
Query: 45 DRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIA--RDNLNVKI- 100
DR ++E ++GTA G+A+ G P+V F AF A+EQ+ + + R+ K+
Sbjct: 56 DRCTDTPLAEAGILGTAVGMAMYGLRPVVEMQFDAFAYPAFEQVVSHVTKMRNRTRGKMP 115
Query: 101 --VATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPA---DAYATRALLYEIVEDHGP 155
+ + + G H A P + VV PA DAY L I D
Sbjct: 116 LPLTIRVPYGGGIGGVEHHSDSSEAYYMATPGLHVVTPATVADAYGL--LRASIASDDPV 173
Query: 156 AYMRLGRDFAPRVYEDGDEIK----LGKANILRDGSDILFVASGVMVSVALEVAENLKGV 211
++ R + + + +E +G+A + R G + G ++V +E AE +
Sbjct: 174 VFLEPKRLYWSKDSWNPEEPASVEPMGRAVVRRSGRSATLITYGPSLAVCMEAAEAARAE 233
Query: 212 GIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
G D V+D+ ++ P D+ T+ R+ + + E FGG GG +A ++E+
Sbjct: 234 GWDLEVVDLRSLVPFDDETVCASVRRTGRAVVVHESGSFGGPGGEIAARVTER 286
>pir||E82872 transketolase I UU586 [imported] - Ureaplasma urealyticum
>gi|6899596|gb|AAF31000.1|AE002157_5 (AE002157)
transketolase I [Ureaplasma urealyticum]
Length = 653
Score = 74.1 bits (179), Expect = 2e-12
Identities = 83/309 (26%), Positives = 136/309 (43%), Gaps = 45/309 (14%)
Query: 21 KDVIVVDADVKNSTKTVYFENQFPDR----FIQVGISEQDMIGTAAGLAI-AGKIPIVSA 75
K +V+ AD+ ST T E F D +I+ GI E M G G+++ G I
Sbjct: 362 KSALVLSADLAKSTFTKIGEGAFNDNHKNPYIKFGIREFAMAGAMNGISLHQGVKAIGGT 421
Query: 76 FAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVV 135
F AF IR A NL + +H ++ DG +HQ ++ + ++R +PN++V+
Sbjct: 422 FLAFSDYMKPAIR-LAAISNLANLFIFSHDSYAVGGDGPTHQPVDQLPMLRAIPNVEVIR 480
Query: 136 PADAYATR-ALLYEIVEDHGPAYMRLGR-------DFAPRVYEDGDEIKLGKANILRDGS 187
PAD Y + AL Y + P + R D P+ + G I + +D
Sbjct: 481 PADHYEVKYALSYSFKQKQKPICLITSRQTIKQINDQKPQDFSKGAYIINSPFSFCKD-V 539
Query: 188 DILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEE- 246
D +ASG VS+A + A+ L + H +K I + NL + L +
Sbjct: 540 DYTIIASGSEVSLANDAAKEL---------FEKHKLK-------IKVISAFNLNLFLRQK 583
Query: 247 ----HTIFGGLGGAVA-EALSEKM-------PRRVIRIGSTTFGRSSRDYLSLLDRYGLS 294
++ G +A EA SE + + I+I + FGRS+ D L++ +G S
Sbjct: 584 PEDIKSLLASKNGLLAIEASSEMLWWKLSIYTNKFIQIAANQFGRSA-DGDKLMNEFGFS 642
Query: 295 VNKVYSKVL 303
V + +++L
Sbjct: 643 VKNIINQLL 651
>pir||S77342 probable pyruvate dehydrogenase (lipoamide) (EC 1.2.4.1) E1 beta
chain - Synechocystis sp. (strain PCC 6803)
>gi|1652524|dbj|BAA17445.1| (D90906) pyruvate
dehydrogenase E1 beta subunit [Synechocystis sp.]
Length = 324
Score = 73.4 bits (177), Expect = 3e-12
Identities = 72/281 (25%), Positives = 123/281 (43%), Gaps = 25/281 (8%)
Query: 15 EIGRKNKDVIVVDADVK------NSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAG 68
E+GR + +V+V+ DV TK +Y E R + I+E G A G A+ G
Sbjct: 17 EMGR-DVNVLVLGEDVGLYGGSYKVTKDLY-EKYGEMRVLDTPIAENSFTGMAVGAAMTG 74
Query: 69 KIPIVSAF-AAFLMRAWEQIRNTIAR------DNLNVKIVATHSGFSDFLDGSSH-QCLE 120
P++ FL+ A+ QI N N + +V G G+ H Q LE
Sbjct: 75 LRPVIEGMNMGFLLLAFNQIANNAGMLRYTSGGNYQIPMVIRGPGGVGRQLGAEHSQRLE 134
Query: 121 DIALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMR---LGRDFAPRVYEDGDEIKL 177
A +P +K+V + Y + LL + D+ P L + + + + L
Sbjct: 135 --AYFHAVPGLKIVACSTPYNAKGLLKAAIRDNNPVLFFEHVLLYNLKENLPDYEYIVPL 192
Query: 178 GKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARK 237
KA ++R G D+ + M L+ + L+ G D ++D+ ++KP D T+ +K
Sbjct: 193 DKAEVVRPGKDVTILTYSRMRHHCLQALKTLEKEGYDPEIIDLISLKPFDMETISASVKK 252
Query: 238 VNLVITLEEHTIFGGLG----GAVAEALSEKMPRRVIRIGS 274
+ VI +EE GG+G + + L +++ V+R+ S
Sbjct: 253 THRVIIVEECMKTGGIGAELIALINDHLFDELDGPVVRLSS 293
>pir||D71420 hypothetical protein - Arabidopsis thaliana
Length = 703
Score = 73.0 bits (176), Expect = 4e-12
Identities = 68/273 (24%), Positives = 107/273 (38%), Gaps = 44/273 (16%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
+S+ F LV +KDV+ + A + T F+ +FP R VGI+EQ
Sbjct: 406 QSYTTYFAEALVAEAEVDKDVVAIHAAMGGGTGLNLFQRRFPTRCFDVGIAEQ------- 458
Query: 63 GLAIAGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
+ + + L V+ +G DG +H D+
Sbjct: 459 ----------------------HAVVHDVDLQKLPVRFAMDRAGLVG-ADGPTHCGAFDV 495
Query: 123 ALMRVLPNMKVVVPAD-AYATRALLYEIVEDHGPAYMRL------------GRDFAPRVY 169
M LPNM V+ P+D A + + D P+ R G P
Sbjct: 496 TFMACLPNMIVMAPSDEADLFNMVATAVAIDDRPSCFRYPRGNGIGVALPPGNKGVPIEK 555
Query: 170 EDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDER 229
++GK IL++G + + G V L A L+ G++ V D KPLD
Sbjct: 556 ISLGVFQIGKGRILKEGERVALLGYGSAVQSCLGAAVMLEERGLNVTVADARFCKPLDRA 615
Query: 230 TLINLARKVNLVITLEEHTIFGGLGGAVAEALS 262
+ +LA+ ++IT+EE +I GG G V + L+
Sbjct: 616 LIRSLAKSHEVLITVEEGSI-GGFGSHVVQFLA 647
>sp|P46375|FAS3_RHOFA HYPOTHETICAL 33.6 KD PROTEIN IN FASCIATION LOCUS PRECURSOR (ORF3)
>gi|1076046|pir||C55578 hypothetical protein (ipt 5'
region) - Rhodococcus fascians plasmid pFiD188
>gi|455003|emb|CAA82743.1| (Z29635) orf3 [Rhodococcus
fascians]
Length = 312
Score = 73.0 bits (176), Expect = 4e-12
Identities = 74/273 (27%), Positives = 121/273 (44%), Gaps = 23/273 (8%)
Query: 8 SFGRTLVEIGRKNKDVIVVDADV-KNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLAI 66
+FG T+ + +VV AD+ + K + P+R I VGI EQ M+G A GLA+
Sbjct: 20 AFGTTMSGALETDPRAVVVLADIGAHLFKAAAIAD--PNRVINVGIREQLMMGVAGGLAM 77
Query: 67 AGKIPIVSAFAAFLM-RAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDIALM 125
G P+V AAFL+ R EQI+ A+ ++ +V+ + + SH DI ++
Sbjct: 78 CGMRPVVHTVAAFLVERPLEQIKLNFAQQDVGAVLVSWGASYDLSEFAFSHFTPGDITVI 137
Query: 126 RVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKANILRD 185
+PN V VP LL E + G Y+RL + +V ++ ++
Sbjct: 138 DSMPNWTVHVPGHPQEAADLLLESLPGDGRVYLRL----SSQVNRYPHAVRGTSFTPIKY 193
Query: 186 GSDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTLINLARKVNL--VIT 243
G+ + +A G + L L D +L T++P D L + VN V+
Sbjct: 194 GTRGVVLAVGPCLDAVLSATSML-----DVTILYAATIRPFDATGLCAAVQAVNRPNVVL 248
Query: 244 LEEHTIFGGLGGAVAEALSEKM---PRRVIRIG 273
+E + L G A +S + P R++ +G
Sbjct: 249 VEPY-----LAGTSAHQVSSSLVSHPHRLLSLG 276
>pir||F72548 probable pyruvate dehydrogenase E1 component, beta subunit APE1674
- Aeropyrum pernix (strain K1)
>gi|5105362|dbj|BAA80675.1| (AP000062) 325aa long
hypothetical pyruvate dehydrogenase E1 component, beta
subunit [Aeropyrum pernix]
Length = 325
Score = 72.2 bits (174), Expect = 7e-12
Identities = 67/274 (24%), Positives = 117/274 (42%), Gaps = 18/274 (6%)
Query: 7 ESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRF-----IQVGISEQDMIGTA 61
++ L E R++K V+V+ DV D F I ++E ++ A
Sbjct: 8 QALNTALREEMRRDKSVVVLGEDVGRRGGVFLVTEGLIDEFGEERVIDTPLTEMGIVAFA 67
Query: 62 AGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIARDNL------NVKIVATHSGFSDFLDGS 114
G+A+ G P+ F F+ A++QI N A NV +V G
Sbjct: 68 IGMAMYGLRPVAEIQFIDFIYEAFDQIVNNAAWYRFRSGGMYNVPLVIRGPCCGGIRGGM 127
Query: 115 SHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVE-DHGPAYMR---LGRDFAPRVYE 170
H + + P + VV+P+ Y + LL + D ++ + R V +
Sbjct: 128 HHSQSNEPYFIHT-PGLYVVMPSTPYDAKGLLKSSIRSDDAVIFLEPKSIYRTIREEVPD 186
Query: 171 DGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKGV-GIDAGVLDMHTVKPLDER 229
+ I LG+A ++++GSD+ V G MV +A E AE L+ G ++D+ T++P D+
Sbjct: 187 NDYTIPLGQARLVQEGSDVTLVTWGAMVHLAKEAAELLREKRGWSIEIIDLRTLQPWDKD 246
Query: 230 TLINLARKVNLVITLEEHTIFGGLGGAVAEALSE 263
++ K ++ + E G G +A +SE
Sbjct: 247 MVVKSLEKTGRLVIVHEARKILGPGAEIAAYISE 280
>gb|AAB58980.1| (L35343) TPP-dependent acetoin dehydrogenase beta-subunit
[Pseudomonas putida] >gi|1093518|prf||2104227C acetoin
dehydrogenase:SUBUNIT=beta [Pseudomonas putida]
Length = 340
Score = 71.8 bits (173), Expect = 1e-11
Identities = 56/184 (30%), Positives = 82/184 (44%), Gaps = 11/184 (5%)
Query: 34 TKTVYFENQFPDRFIQVGISEQDMIGTAAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIA 92
TK +Y +QFP R + +SE +G A G A G P+ F F +QI N A
Sbjct: 52 TKGLY--HQFPGRVLDAPLSEIGYVGAAVGAATQGLRPVCELMFVDFAGCCLDQILNQAA 109
Query: 93 R-----DNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLY 147
+ V + + + L ++ +L +P +KVV P+ Y + LL
Sbjct: 110 KFRYMFGGKAVTPLVMRTMYGAGLRAAAQHSQMLTSLWTHIPGLKVVCPSSPYDAKGLLI 169
Query: 148 EIVEDHGPAYM---RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEV 204
+ + D+ P +L V E+ + G+AN LRDG D+ V G MV VALE
Sbjct: 170 QAIRDNDPVIFCEHKLLYSMQGEVPEEVYTVPFGEANFLRDGDDVTLVTYGRMVHVALEA 229
Query: 205 AENL 208
A NL
Sbjct: 230 ANNL 233
>sp|P57195|TKT_BUCAI TRANSKETOLASE (TK) >gi|10038778|dbj|BAB12813.1| (AP001118)
transketolase [Buchnera sp. APS]
Length = 665
Score = 71.4 bits (172), Expect = 1e-11
Identities = 79/325 (24%), Positives = 140/325 (42%), Gaps = 39/325 (12%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVY-----FENQFPDRFIQVGISEQDMIGT 60
R++ TL + ++I AD+ S T++ ++ +I G+ E M
Sbjct: 358 RKASQNTLEKYAMILPELIGGSADLSPSNLTMWSRCNSIKDNLSGNYIHYGVREFGMTAI 417
Query: 61 AAGLAI-AGKIPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCL 119
A G++ G IP + F F+ A +R ++ V TH DG +HQ +
Sbjct: 418 ANGISHHGGFIPYTATFLMFVEYARNAVRMAALMCTKHI-FVYTHDSIGLGEDGPTHQPV 476
Query: 120 EDIALMRVLPNMKVVVPADAYATRALLYEIVE-DHGPAYMRLGR---DFAPRVYEDGDEI 175
E ++ +R+ PN+ V P+D T + +E GP + L R D R E + I
Sbjct: 477 EQLSSLRITPNIDVWRPSDQVETAVAWKKAIEKTSGPTALILSRQNLDQFERSSEQLENI 536
Query: 176 KLGKANILRDGS---DILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTL- 231
G A IL D DI+F+++G ++V L A+ L +G V+ M D +
Sbjct: 537 SYG-AYILYDSKKRLDIIFISTGSELNVTLIAAKKLASLGYSVRVVSMPCTSVFDRQDAS 595
Query: 232 -------INLARKVNLVITLEEHTI-FGGLGGAVAEALSEKMPRRVIRIGSTTFGRSSRD 283
+A++V + ++E+ + G+ G + IG TFG S+
Sbjct: 596 YKEFVLPTYVAKRVAVEASIEDFWYKYVGINGVI--------------IGMKTFGESA-P 640
Query: 284 YLSLLDRYGLSVNKVYSKVLEVVKN 308
L ++G +V +++K L ++K+
Sbjct: 641 AEDLFKKFGFTVQNIFNKSLILLKS 665
>gb|AAF45391.1| (AE003270) CG17691 gene product [Drosophila melanogaster]
Length = 329
Score = 71.0 bits (171), Expect = 2e-11
Identities = 65/237 (27%), Positives = 99/237 (41%), Gaps = 23/237 (9%)
Query: 46 RFIQVGISEQDMIGT-AAGLAIAGKIPIVSA-FAAFLMRAWEQIRNTIAR---------- 93
R + EQ + G A G+A G I FA ++ +++QI N A+
Sbjct: 54 RVFNTPLCEQGIAGYFAIGVANTGATAIAEIQFADYIFPSFDQIVNEAAKYRYRSGGLFD 113
Query: 94 -DNLNVKIVATHSGFSDFLDGSSHQCLEDIALMRVLPNMKVVVPADAYATRALLYEIVED 152
+L ++ G S + A P ++VVVP + L+ + D
Sbjct: 114 CGSLTFRVPCGAVGHGALYHSQSPE-----AYFAHTPGLRVVVPRGPIKAKGLILACIRD 168
Query: 153 HGPAYM----RLGRDFAPRVYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENL 208
P + L R V + +LGKA+ILR G D+ + G V V LEVAE
Sbjct: 169 PNPCIVFEPKTLYRAAVEEVPAEYYTSQLGKADILRHGKDVTLIGWGTQVHVLLEVAEIA 228
Query: 209 KG-VGIDAGVLDMHTVKPLDERTLINLARKVNLVITLEEHTIFGGLGGAVAEALSEK 264
K + ID V+D+ ++ P D T+ A+K VI E + G G +A + EK
Sbjct: 229 KSTLNIDCEVIDLVSILPWDAITICTSAKKTGRVIIAHEAPLTQGFGSELASYIQEK 285
>gb|AAC83349.1| (AF086822) dihydroxyacetone synthase [Candida boidinii]
Length = 706
Score = 69.9 bits (168), Expect = 4e-11
Identities = 65/233 (27%), Positives = 98/233 (41%), Gaps = 25/233 (10%)
Query: 22 DVIVVDADVKNSTK-----TVYFEN-----------QFPDRFIQVGISEQDMIGTAAGLA 65
+VI AD+ S + YFEN + R+++ GI E M A GLA
Sbjct: 383 NVIAGSADLSVSVNLPWPGSKYFENPQLATQCGLAGDYSGRYVEFGIREHCMCAIANGLA 442
Query: 66 IAGK---IPIVSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLEDI 122
K +PI S+F F + A +R A L +ATH DG +HQ +
Sbjct: 443 AFNKGTFLPITSSFYMFYLYAAPALRMA-ALQELKAIHIATHDSIGAGEDGPTHQPIAQS 501
Query: 123 ALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKAN- 181
AL R +PN + P DA R L + VE L R P+ Y I+L K
Sbjct: 502 ALWRAMPNFYYMRPGDASEVRGLFEKAVELPLSTLFSLSRHEVPQ-YPGKSSIELAKRGG 560
Query: 182 -ILRDG--SDILFVASGVMVSVALEVAENLKGVGIDAGVLDMHTVKPLDERTL 231
+ D +DI + +G + A++ A L+ G+ +L + DE+++
Sbjct: 561 YVFEDAKDADIQLIGAGSELEQAVKTARILRSRGLKVRILSFPCQRLFDEQSV 613
>gb|AAC04864.1| (AF047336) transketolase [Drosophila heteroneura]
Length = 113
Score = 69.1 bits (166), Expect = 6e-11
Identities = 35/84 (41%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAAGLA 65
R ++G L +IG N VI +D D KNST + N +P+R+I+ I+EQ+++G A G A
Sbjct: 26 RLAYGTALAKIGADNDRVIALDGDTKNSTYSDKLRNAYPERYIECFIAEQNLVGVAIGTA 85
Query: 66 IAGK-IPIVSAFAAFLMRAWEQIR 88
+ + VS FA F RA++QIR
Sbjct: 86 CRRRTVAFVSTFATFFTRAYDQIR 109
>pir||T50967 probable pyruvate dehydrogenase (lipoamide) beta chain precursor
(PDB1) [imported] - Neurospora crassa
>gi|9367270|emb|CAB97287.1| (AL389890) probable pyruvate
dehydrogenase (lipoamide) beta chain precursor (PDB1)
[Neurospora crassa]
Length = 379
Score = 69.1 bits (166), Expect = 6e-11
Identities = 71/271 (26%), Positives = 114/271 (41%), Gaps = 19/271 (7%)
Query: 6 RESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRF-----IQVGISEQDMIGT 60
R++ L E N V V+ +V DRF I I+E G
Sbjct: 55 RDALNEALAEELEANDKVFVMGEEVAQYNGAYKVTKGLLDRFGDRRVIDTPITEMGFTGL 114
Query: 61 AAGLAIAGKIPIVSAFAA-FLMRAWEQIRNTIARDNLNVKIVA----THSGFSDFLDGSS 115
A G A++G P+ F M++ + I N+ A+ + T G + F G +
Sbjct: 115 AVGAALSGLHPVCEFMTFNFAMQSIDHIVNSAAKTLYMSGGIQPCNITFRGPNGFAAGVA 174
Query: 116 HQCLEDI-ALMRVLPNMKVVVPADAYATRALLYEIVEDHGPAY-----MRLGRDF--APR 167
Q +D A +P +KVV P A + LL + D P + G+ F +
Sbjct: 175 AQHSQDYSAWYGSVPGLKVVSPWSAEDAKGLLKAAIRDPNPVIVLENELMYGQVFPMSEA 234
Query: 168 VYEDGDEIKLGKANILRDGSDILFVASGVMVSVALEVAENLKG-VGIDAGVLDMHTVKPL 226
+D I GKA I R GSD+ V V ++ AE LK G++ VL++ ++KPL
Sbjct: 235 AQKDDFVIPFGKAKIERAGSDLTIVTMSRCVGQSIVAAEALKKKYGVEVEVLNLRSIKPL 294
Query: 227 DERTLINLARKVNLVITLEEHTIFGGLGGAV 257
D ++ +K + ++T+E G+G +
Sbjct: 295 DLDAILKSIKKTHRLMTVESGFPSYGVGAEI 325
>gb|AAD03740.2| (AF111814) 1-deoxy-D-xylulose 5-phosphate synthase [Plasmodium
falciparum]
Length = 1205
Score = 68.7 bits (165), Expect = 8e-11
Identities = 45/182 (24%), Positives = 95/182 (51%), Gaps = 8/182 (4%)
Query: 3 ESFRESFGRTLVEIGRKNKDVIVVDADVKNSTKTVYFENQFPDRFIQVGISEQDMIGTAA 62
E+F + + +++ +K++++I + + + V ++P+ VGI+EQ + AA
Sbjct: 828 ETFTDIYTNEMLKYLKKDRNIIFLSPAMLGGSGLVKISERYPNNVYDVGIAEQHSVTFAA 887
Query: 63 GLAIAGKIPI-VSAFAAFLMRAWEQIRNTIARDNLNVKIVATHSGFSDFLDGSSHQCLED 121
+A+ K+ I + ++ FL RA++QI + + N+ +K++ SG DG++HQ + D
Sbjct: 888 AMAMNKKLKIQLCIYSTFLQRAYDQIIHDLNLQNIPLKVIIGRSGLVG-EDGATHQGIYD 946
Query: 122 IALMRVLPNMKVVVPADAY-ATRALLYEIVEDHGPAYMRLGRDFAPRVYEDGDEIKLGKA 180
++ + L N ++ P++ RAL + ++ Y+R+ PR+ D+ G
Sbjct: 947 LSYLGTLNNAYIISPSNQVDLKRALRFAYLDKDHSVYIRI-----PRMNILSDKYMKGYL 1001
Query: 181 NI 182
NI
Sbjct: 1002 NI 1003
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.139 0.384
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106689843
Number of Sequences: 2977
Number of extensions: 4255244
Number of successful extensions: 10810
Number of sequences better than 1.0e-10: 157
Number of HSP's better than 0.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 10503
Number of HSP's gapped (non-prelim): 159
length of query: 317
length of database: 189,106,746
effective HSP length: 58
effective length of query: 259
effective length of database: 154,394,500
effective search space: 39988175500
effective search space used: 39988175500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)