BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0299 (aroD) DE:3-dehydroquinate dehydratase (aroD)
(215 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9V1H8|AROD_PYRAB 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUIN... 418 e-116
sp|Q58849|AROD_METJA 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUIN... 111 8e-24
sp|O66440|AROD_AQUAE 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUIN... 102 4e-21
sp|O26666|AROD_METTH 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUIN... 101 9e-21
gb|AAF08579.1|AC011623_12 (AC011623) putative dehydroquinase shi... 92 6e-18
gi|11497844 3-dehydroquinate dehydratase (aroD) [Archaeoglobus f... 88 9e-17
pir||S46210 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikima... 86 3e-16
pir||T06264 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikima... 83 3e-15
pir||S48698 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikima... 78 8e-14
sp|Q9JYT0|AROD_NEIMB 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUIN... 75 7e-13
sp|P36923|EBSD_ENTFA PROBABLE 3-DEHYDROQUINATE DEHYDRATASE (3-DE... 73 3e-12
pir||G81860 3-dehydroquinate dehydratase (EC 4.2.1.10) NMA1659 [... 73 3e-12
sp|Q9JTR9|AROD_NEIMA 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUIN... 73 3e-12
pir||BVASA1 aroM protein - Emericella nidulans 72 4e-12
sp|P07547|ARO1_EMENI PENTAFUNCTIONAL AROM POLYPEPTIDE [INCLUDES:... 72 4e-12
sp|P05194|AROD_ECOLI 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUIN... 72 4e-12
gi|6320332 pentafunctional arom polypeptide (contains: 3-dehydro... 72 6e-12
sp|O87007|AROD_SHIDY 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUIN... 72 6e-12
pir||T50113 pentafunctional enzyme arom [imported] - fission yea... 72 6e-12
>sp|Q9V1H8|AROD_PYRAB 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
>gi|7436863|pir||D75161 3-dehydroquinate dehydratase
(arod) PAB0299 - Pyrococcus abyssi (strain Orsay)
>gi|5457881|emb|CAB49371.1| (AJ248284) 3-dehydroquinate
dehydratase (aroD) [Pyrococcus abyssi]
Length = 215
Score = 418 bits (1062), Expect = e-116
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MIATVILADSIKEAIEKIKSSSSDLYELRADSLKDYSKLELLEPYSEKLVVTIRSKDEGG 60
MIATVILADSIKEAIEKIKSSSSDLYELRADSLKDYSKLELLEPYSEKLVVTIRSKDEGG
Sbjct: 1 MIATVILADSIKEAIEKIKSSSSDLYELRADSLKDYSKLELLEPYSEKLVVTIRSKDEGG 60
Query: 61 FKELSDEKRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVGSRVILSYHNFRETPPF 120
FKELSDEKRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVGSRVILSYHNFRETPPF
Sbjct: 61 FKELSDEKRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVGSRVILSYHNFRETPPF 120
Query: 121 GVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFADNLIAFCMGSKGKISRIFSS 180
GVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFADNLIAFCMGSKGKISRIFSS
Sbjct: 121 GVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFADNLIAFCMGSKGKISRIFSS 180
Query: 181 MYSPITYVALDKKAAPGQLTLEELRVILKILGEGR 215
MYSPITYVALDKKAAPGQLTLEELRVILKILGEGR
Sbjct: 181 MYSPITYVALDKKAAPGQLTLEELRVILKILGEGR 215
>sp|Q58849|AROD_METJA 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
>gi|2127719|pir||E64481 3-dehydroquinate dehydratase (EC
4.2.1.10) - Methanococcus jannaschii
>gi|1592097|gb|AAB99464.1| (U67586) 3-dehydroquinate
dehydratase (aroD) [Methanococcus jannaschii]
Length = 220
Score = 111 bits (274), Expect = 8e-24
Identities = 67/218 (30%), Positives = 125/218 (56%), Gaps = 8/218 (3%)
Query: 1 MIATVILADSIKEAIEKIKS--SSSDLYELRADSLKDYSKLELLEPYSEKLVVTIRSKDE 58
MI ++ DS+++AI+ + +D+ E R D LK+ S+ ++ + ++T+R+ E
Sbjct: 1 MICLPVVEDSVEKAIKTAEKYLEIADIVEFRIDMLKEVSEEDIEKFAKYPCIITVRADWE 60
Query: 59 GGFKELSDEKRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVGS--RVILSYHNFRE 116
GG+ + ++E+RL L K +E ++VD+E R + E+++ +GS ++I+SYH+F +
Sbjct: 61 GGYWKGNNEERLNLIKKAIECNAKFVDIELREEKNKELVKFRDEIGSKTKIIISYHDFEK 120
Query: 117 TPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIR-LYEFADNLIAFCMGSKGKIS 175
TP L ++E S G DI K T A+S +D + I+ + ++ +I MG KGK++
Sbjct: 121 TPSKEKLVEIVEKALSIG-DIAKFATMANSKEDVLNILEVINKYPGKIIGIGMGEKGKLT 179
Query: 176 RIFSSMYSPITYVA--LDKKAAPGQLTLEELRVILKIL 211
RI + I A K +APGQ+ ++ L+ I +++
Sbjct: 180 RILGVYFGSILTFASYKGKSSAPGQVDIDTLKEIWRLM 217
>sp|O66440|AROD_AQUAE 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
>gi|7436864|pir||E70301 3-dehydroquinate dehydratase -
Aquifex aeolicus >gi|2982763|gb|AAC06389.1| (AE000669)
3-dehydroquinate dehydratase [Aquifex aeolicus]
Length = 219
Score = 102 bits (251), Expect = 4e-21
Identities = 74/215 (34%), Positives = 115/215 (53%), Gaps = 18/215 (8%)
Query: 1 MIATVILADSIKEAIEKIKSSSSDLYELRADSLKDYS------KLELLEPYSEKLVVTIR 54
+IA + + E ++K K +D+ ELR D D S KLE + K ++TIR
Sbjct: 2 LIAVPLDDTNFSENLKKAKEKGADIVELRVDQFSDTSLNYVKEKLEEVHSQGLKTILTIR 61
Query: 55 SKDEGGFKELSDEKRLELYSKFLEIKPR--YVDVEFRSK-IKDEVMEIAKRVGSRVILSY 111
S +EGG +E+ + + L F E+ P Y D+E S+ + ++ I K G ++I+SY
Sbjct: 62 SPEEGG-REVKNREEL-----FEELSPLSDYTDIELSSRGLLVKLYNITKEAGKKLIISY 115
Query: 112 HNFRETPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRL-YEFADNLIAFCMGS 170
HNF TPP ++ +L + G I KI A+S +D R++ + + I MG
Sbjct: 116 HNFELTPPNWIIREVLREGYRYGG-IPKIAVKANSYEDVARLLCISRQVEGEKILISMGD 174
Query: 171 KGKISRIFSSMY-SPITYVALDKKAAPGQLTLEEL 204
GKISR+ ++ S ITY +L+K APGQ+ LEE+
Sbjct: 175 YGKISRLAGYVFGSVITYCSLEKAFAPGQIPLEEM 209
>sp|O26666|AROD_METTH 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
>gi|7436861|pir||H69174 3-dehydroquinate dehydratase -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621643|gb|AAB85072.1| (AE000839) 3-dehydroquinate
dehydratase [Methanobacterium thermoautotrophicum]
Length = 221
Score = 101 bits (248), Expect = 9e-21
Identities = 66/212 (31%), Positives = 117/212 (55%), Gaps = 15/212 (7%)
Query: 8 ADSIKEAIEKIKSSSSDLYELRADSLKDYSKL---ELLEPYSEKLVVTIRSKDEGGFKEL 64
A + E+ + + +D+ E+R D L++ ++ EL+E ++ T RS EGG
Sbjct: 14 APEVTESAGRAIDAGADILEIRIDGLQNPGEVNIRELIEDIGFPVIATNRSPVEGGHFSG 73
Query: 65 SDEKRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVGS--RVILSYHNFRETPPFGV 122
S+++R++L E+ +VD+E S +D I + GS R I+SYHNFRETP
Sbjct: 74 SEDERIKLLMAAAEVAD-FVDIELSSARED----IERVTGSARRSIVSYHNFRETPSLEA 128
Query: 123 LYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFADNLIAFCMGSKGKISRIFSSMY 182
L ++ M E DI K+ + D + +++L F ++ +A MG GK +R+ ++++
Sbjct: 129 LLRIVR-MAKEMGDIAKVAVMPENLADTLVVLQLLTFEEDTVAISMGELGKYTRVAAALF 187
Query: 183 -SPITYVALDKKAAPGQLTLEELRVILKILGE 213
SPIT+ ++ + APGQ+ ++ R K++GE
Sbjct: 188 GSPITFASMGRGTAPGQMDVDVTR---KMIGE 216
>gb|AAF08579.1|AC011623_12 (AC011623) putative dehydroquinase shikimate dehydrogenase
[Arabidopsis thaliana]
Length = 603
Score = 91.7 bits (224), Expect = 6e-18
Identities = 72/216 (33%), Positives = 112/216 (51%), Gaps = 12/216 (5%)
Query: 1 MIATVILADSIKEAI---EKIKSSSSDLYELRADSLKDYSKLELLEPYSEK----LVVTI 53
+I ++ADSI + + K +DL E+R D LKD++ LE L+ +K + T
Sbjct: 95 LICAPVMADSIDKMVIETSKAHELGADLVEIRLDWLKDFNPLEDLKTIIKKSPLPTLFTY 154
Query: 54 RSKDEGGFKELSDEKRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVGS-RVILSYH 112
R K EGG E + +R ++ +E+ Y+DVE + + K+ G +VI+S H
Sbjct: 155 RPKWEGGQYEGDENERRDVLRLAMELGADYIDVELQVASEFIKSIDGKKPGKFKVIVSSH 214
Query: 113 NFRETPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFAD-NLIAFCMGSK 171
N++ TP L L+ ++ GADIVKI T A D R+ + A I MG +
Sbjct: 215 NYQNTPSVEDLDGLVARIQQTGADIVKIATTAVDIADVARMFHITSKAQVPTIGLVMGER 274
Query: 172 GKISRIFSSMYSP-ITYVALD--KKAAPGQLTLEEL 204
G +SRI S + +T+ LD K +APGQ T+++L
Sbjct: 275 GLMSRILCSKFGGYLTFGTLDSSKVSAPGQPTIKDL 310
>gi|11497844 3-dehydroquinate dehydratase (aroD) [Archaeoglobus fulgidus]
>gi|8469115|sp|O30011|AROD_ARCFU 3-DEHYDROQUINATE
DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
>gi|7482876|pir||D69278 3-dehydroquinate dehydratase
(aroD) homolog - Archaeoglobus fulgidus
>gi|2650413|gb|AAB91004.1| (AE001090) 3-dehydroquinate
dehydratase (aroD) [Archaeoglobus fulgidus]
Length = 196
Score = 87.8 bits (214), Expect = 9e-17
Identities = 61/195 (31%), Positives = 102/195 (52%), Gaps = 16/195 (8%)
Query: 20 SSSSDLYELRADSLKDYSKLELLEPYSEKLVVTIRSKDEGGFKELSDEKRLELYSK-FLE 78
+ +D+ ELR D L D+S + ++ ++T R +GG E + +R+E + F
Sbjct: 16 AEKADVVELRID-LFDFSGARV----DKEKILTCRRVSDGGKFEGDERERIEKMKRAFDS 70
Query: 79 IKPRYVDVEFRSKIKDEVMEIAKRVGSRVILSYHNFRETPPFGVLYNLLEDMESEGADIV 138
+ P YVD+E S + D + R+I SYHNF TP + L ++E D+V
Sbjct: 71 LNPDYVDLE--SDLPDSAFDF----NCRIIESYHNFIRTPDYSELKGIVEGRRG---DLV 121
Query: 139 KIVTHASSPKDNIRIIRLYEFADNLIAFCMGSKGKISRIFSS-MYSPITYVALDKKAAPG 197
KI T S +D I+R+ D+++AF MG + +R+ ++ + SP Y + APG
Sbjct: 122 KIATMGKSKRDVETIVRILTNYDDVVAFLMGERFSFTRVLAAYLGSPFIYCYVGSPKAPG 181
Query: 198 QLTLEELRVILKILG 212
Q++L++ R I+ LG
Sbjct: 182 QISLDDAREIISRLG 196
>pir||S46210 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikimate
5-dehydrogenase (EC 1.1.1.25) precursor - common tobacco
(fragment) >gi|535771|gb|AAA34069.1| (L32794)
dehydroquinate dehydratase/shikimate dehydrogenase
[Nicotiana tabacum]
Length = 579
Score = 86.2 bits (210), Expect = 3e-16
Identities = 66/216 (30%), Positives = 113/216 (51%), Gaps = 12/216 (5%)
Query: 1 MIATVILADSIKEAI---EKIKSSSSDLYELRADSLKDYSKLELLEPYSEK----LVVTI 53
+I I+AD++ + + +K K S +DL E+R DSLK ++ ++ ++ + T
Sbjct: 33 LICAPIMADTVDQMLNLMQKAKISGADLVEVRLDSLKSFNPQSDIDTIIKQSPLPTLFTY 92
Query: 54 RSKDEGGFKELSDEKRLELYSKFLEIKPRYVDVEFRSKIK-DEVMEIAKRVGSRVILSYH 112
R EGG + RL+ +E+ Y+DVE ++ + + + K +VI+S H
Sbjct: 93 RPTWEGGQYAGDEVSRLDALRVAMELGADYIDVELKAIDEFNTALHGNKSAKCKVIVSSH 152
Query: 113 NFRETPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFAD-NLIAFCMGSK 171
N+ TP L NL+ +++ GADIVK T A D R+ ++ + +IA MG K
Sbjct: 153 NYDNTPSSEELGNLVARIQASGADIVKFATTALDIMDVARVFQITVHSQVPIIAMVMGEK 212
Query: 172 GKISRIFSSMYSP-ITYVALD--KKAAPGQLTLEEL 204
G +SRI + +T+ L+ K +APGQ T+++L
Sbjct: 213 GLMSRILCPKFGGYLTFGTLEVGKVSAPGQPTIKDL 248
>pir||T06264 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikimate
5-dehydrogenase (EC 1.1.1.25) - tomato
>gi|3169883|gb|AAC17991.1| (AF033194) dehydroquinate
dehydratase/shikimate:NADP oxidoreductase [Lycopersicon
esculentum] >gi|3169888|gb|AAC17993.1| (AF034411)
dehydroquinate dehydratase/shikimate:NADP oxidoreductase
[Lycopersicon esculentum]
Length = 545
Score = 82.7 bits (201), Expect = 3e-15
Identities = 72/235 (30%), Positives = 116/235 (48%), Gaps = 31/235 (13%)
Query: 1 MIATVILADSIKEAI---EKIKSSSSDLYELRADSLKDYSK------------LELLEPY 45
+I I+ADS+ + + +K K S +DL E+R DSLK ++ L L Y
Sbjct: 23 LICAPIMADSVDQMLILMQKAKISGADLVEVRVDSLKSFNPRPDIDTLIKQCPLPTLFTY 82
Query: 46 SEKL-----VVTIRSKD------EGGFKELSDEKRLELYSKFLEIKPRYVDVEFRSKIK- 93
S L ++ IR EGG ++ RL+ +E+ Y+DVE ++ +
Sbjct: 83 SYVLGVGQGILLIRYYKGIGPTWEGGQYAGDEKSRLDALRLAMELGADYIDVELKAIGEF 142
Query: 94 DEVMEIAKRVGSRVILSYHNFRETPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRI 153
+ + K ++I+S HN+ TP L NL+ +++ GADIVK T A D R+
Sbjct: 143 NNALHGNKSAKCKLIVSSHNYESTPSAEDLGNLVARIQASGADIVKFATTAQDITDVARV 202
Query: 154 IRLYEFAD-NLIAFCMGSKGKISRIFSSMYSP-ITYVALD--KKAAPGQLTLEEL 204
++ + +IA MG KG +SRI + +T+ L+ K +APGQ T+E+L
Sbjct: 203 FQITVHSQVPIIAMVMGEKGLMSRILCPKFGGYLTFGTLEVGKVSAPGQPTVEDL 257
>pir||S48698 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikimate
5-dehydrogenase (EC 1.1.1.25) precursor - garden pea
(fragment)
Length = 325
Score = 78.0 bits (189), Expect = 8e-14
Identities = 61/219 (27%), Positives = 115/219 (51%), Gaps = 17/219 (7%)
Query: 1 MIATVILADSIKEA---IEKIKSSSSDLYELRADSLKDYSKLELLEPYSEK-----LVVT 52
+I I+ +++++ I+K K + +DL E+R DSL ++ + L + ++ + T
Sbjct: 6 LICVPIMGETVEKMVVDIQKAKLNGADLVEIRLDSLSTFNPHQDLNTFIQQHHSLPFLFT 65
Query: 53 IRSKDEGGFKELSDEKRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRV---GSRVIL 109
R EGG + + +RL+ +E+ YVD+E K+ E + + ++VI+
Sbjct: 66 YRPIWEGGKYDGDENRRLDALRLAVELGADYVDIEL--KVAHEFYDSIRGKMFNKTKVIV 123
Query: 110 SYHNFRETPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFAD-NLIAFCM 168
S HN++ TP L +L+ +++ GADIVKI T A D R+ ++ + I M
Sbjct: 124 SSHNYQYTPSVEDLGDLVARIQATGADIVKIATTAVEITDVARMFQILVHSQVPFIGLVM 183
Query: 169 GSKGKISRIFSSMYSP-ITYVALDK--KAAPGQLTLEEL 204
G +G +SR+ + + +T+ L+ +APGQ T+++L
Sbjct: 184 GDRGLVSRVLCAKFGGYLTFGTLESGVVSAPGQPTIKDL 222
>sp|Q9JYT0|AROD_NEIMB 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
>gi|11268891|pir||G81082 3-dehydroquinate dehydratase
NMB1446 [imported] - Neisseria meningitidis (group B
strain MD58) >gi|7226687|gb|AAF41806.1| (AE002494)
3-dehydroquinate dehydratase [Neisseria meningitidis
MC58]
Length = 254
Score = 74.9 bits (181), Expect = 7e-13
Identities = 64/226 (28%), Positives = 105/226 (46%), Gaps = 20/226 (8%)
Query: 8 ADSIKEAIEKIKSSSSDLYELRADSLKDYSKLELLEPYSEK---------LVVTIRSKDE 58
A + +E+IK+ D+ E RAD L+ + + +++ L+ T R E
Sbjct: 28 AAELSAVLEQIKNMPFDIAEFRADFLECAGSIGEILHHTQTVRDALPDKPLLFTFRRHGE 87
Query: 59 GGFKELSDEKRLELYSKFLEIK-PRYVDVEFRS---KIKDEVMEIAKRVGSRVILSYHNF 114
GG SD+ EL +E + P +D+E S ++ V A++ G +L H F
Sbjct: 88 GGSFPCSDDYYFELLDALIESRLPDIIDIELFSGETAVRCAVAN-AQKNGIAALLCNHEF 146
Query: 115 RETPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRI----IRLYEFADN-LIAFCMG 169
TPP + L+ ME GADI KI S +D + + ++ E A ++ MG
Sbjct: 147 HRTPPQEEIVCRLKQMEDCGADICKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMG 206
Query: 170 SKGKISRIFSSMY-SPITYVALDKKAAPGQLTLEELRVILKILGEG 214
G +SR+ ++ S IT+ + + +APGQ+ + LR L L G
Sbjct: 207 QTGAVSRLAGQVFGSSITFGSGTQNSAPGQIGVSALRATLDCLENG 252
>sp|P36923|EBSD_ENTFA PROBABLE 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I
DHQASE) >gi|1075693|pir||D49939 hypothetical protein
(ebsC 5' region) - Enterococcus faecalis
>gi|388110|gb|AAC36854.1| (L23802) dehydroquinase
homologue [Enterococcus faecalis]
Length = 253
Score = 73.0 bits (176), Expect = 3e-12
Identities = 62/239 (25%), Positives = 119/239 (48%), Gaps = 28/239 (11%)
Query: 2 IATVILADSIKEAIEKIKSSSS---DLYELRAD---SLKDYSKL-----ELLEPYSEK-L 49
I I+A + ++ + + +S + DL E R D ++ D+S + +++E +K L
Sbjct: 18 IVVPIVAPTAEDILAEATASQTLDCDLVEWRLDYYENVADFSDVCNLSQQVMERLGQKPL 77
Query: 50 VVTIRSKDEGGFKELSDEKRLELYSKFLEIKPR-YVDVEFRSK--IKDEVMEIAKRVGSR 106
++T R++ EGG S+E LY + ++ +D+E + D ++ AK+ G +
Sbjct: 78 LLTFRTQKEGGEMAFSEENYFALYHELVKKGALDLLDIELFANPLAADTLIHEAKKAGIK 137
Query: 107 VILSYHNFRETPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFADN---- 162
++L H+F++TP + L M+ ADI KI A P+D ++ L +
Sbjct: 138 IVLCNHDFQKTPSQEEIVARLRQMQMRQADICKI---AVMPQDATDVLTLLSATNEMYTH 194
Query: 163 -----LIAFCMGSKGKISRIFSSMY-SPITYVALDKKAAPGQLTLEELRVILKILGEGR 215
++ MG G ISR+ ++ S +T+ + + +APGQL+++ LR LK + +
Sbjct: 195 YASVPIVTMSMGQLGMISRVTGQLFGSALTFGSAQQASAPGQLSVQVLRNYLKTFEQNK 253
>pir||G81860 3-dehydroquinate dehydratase (EC 4.2.1.10) NMA1659 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380301|emb|CAB84887.1| (AL162756) 3-dehydroquinate
dehydratase [Neisseria meningitidis Z2491]
Length = 265
Score = 72.6 bits (175), Expect = 3e-12
Identities = 62/223 (27%), Positives = 104/223 (45%), Gaps = 20/223 (8%)
Query: 11 IKEAIEKIKSSSSDLYELRADSLKDYSKLELLEPYSEK---------LVVTIRSKDEGGF 61
+ +++IK+ D+ E RAD L+ + + +++ L+ T R EGG
Sbjct: 42 LSAVLDQIKNLPFDIVEFRADFLECAGSIGEVLRHTQTVRDALPDKPLLFTFRRHGEGGS 101
Query: 62 KELSDEKRLELYSKFLEIK-PRYVDVEFRS---KIKDEVMEIAKRVGSRVILSYHNFRET 117
SD+ EL +E + P +D+E S ++ V A++ G +L H F T
Sbjct: 102 FPCSDDYYFELLDALIESRLPDIIDIELFSGETAVRCAVAN-AQKNGIAALLCNHEFHRT 160
Query: 118 PPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRI----IRLYEFADN-LIAFCMGSKG 172
PP + L+ ME GADI KI S +D + + ++ E A ++ MG G
Sbjct: 161 PPQEEIVCRLKQMEDCGADICKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMGQTG 220
Query: 173 KISRIFSSMY-SPITYVALDKKAAPGQLTLEELRVILKILGEG 214
+SR+ ++ S IT+ + + +APGQ+ + LR L L G
Sbjct: 221 AVSRLAGQVFGSSITFGSGTQNSAPGQIGVSALRATLDCLENG 263
>sp|Q9JTR9|AROD_NEIMA 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
Length = 254
Score = 72.6 bits (175), Expect = 3e-12
Identities = 62/223 (27%), Positives = 104/223 (45%), Gaps = 20/223 (8%)
Query: 11 IKEAIEKIKSSSSDLYELRADSLKDYSKLELLEPYSEK---------LVVTIRSKDEGGF 61
+ +++IK+ D+ E RAD L+ + + +++ L+ T R EGG
Sbjct: 31 LSAVLDQIKNLPFDIVEFRADFLECAGSIGEVLRHTQTVRDALPDKPLLFTFRRHGEGGS 90
Query: 62 KELSDEKRLELYSKFLEIK-PRYVDVEFRS---KIKDEVMEIAKRVGSRVILSYHNFRET 117
SD+ EL +E + P +D+E S ++ V A++ G +L H F T
Sbjct: 91 FPCSDDYYFELLDALIESRLPDIIDIELFSGETAVRCAVAN-AQKNGIAALLCNHEFHRT 149
Query: 118 PPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRI----IRLYEFADN-LIAFCMGSKG 172
PP + L+ ME GADI KI S +D + + ++ E A ++ MG G
Sbjct: 150 PPQEEIVCRLKQMEDCGADICKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMGQTG 209
Query: 173 KISRIFSSMY-SPITYVALDKKAAPGQLTLEELRVILKILGEG 214
+SR+ ++ S IT+ + + +APGQ+ + LR L L G
Sbjct: 210 AVSRLAGQVFGSSITFGSGTQNSAPGQIGVSALRATLDCLENG 252
>pir||BVASA1 aroM protein - Emericella nidulans
Length = 1603
Score = 72.2 bits (174), Expect = 4e-12
Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 23/213 (10%)
Query: 23 SDLYELRADSLKD-------------YSKLELLEP-YSEKLVVTIRSKDEGG-FKELSDE 67
SD ELR D LKD +L L + ++ TIR++ +GG F + + +
Sbjct: 1076 SDAVELRVDLLKDPASNNDIPSVDYVVEQLSFLRSRVTLPIIFTIRTQSQGGRFPDNAHD 1135
Query: 68 KRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVG-SRVILSYHNFR-ETPPFGVLYN 125
LELY +VD++ +D + + + G S++I S+H+ + E + +
Sbjct: 1136 AALELYRLAFRSGCEFVDLDIAFP-EDMLRAVTEMKGFSKIIASHHDPKGELSWANMSWI 1194
Query: 126 LLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFADN-----LIAFCMGSKGKISRIFSS 180
+ E DI+K+V A + DN + + +A LIA MG +G++SRI +
Sbjct: 1195 KFYNKALEYGDIIKLVGVARNIDDNTALRKFKNWAAEAHDVPLIAINMGDQGQLSRILNG 1254
Query: 181 MYSPITYVALDKKAAPGQLTLEELRVILKILGE 213
+P+++ +L KAAPGQL+ E+R L ++GE
Sbjct: 1255 FMTPVSHPSLPFKAAPGQLSATEIRKGLSLMGE 1287
>sp|P07547|ARO1_EMENI PENTAFUNCTIONAL AROM POLYPEPTIDE [INCLUDES: 3-DEHYDROQUINATE SYNTHASE
; 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE);
SHIKIMATE 5-DEHYDROGENASE ; SHIKIMATE KINASE ;
3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE
(5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYN>
>gi|3834343|emb|CAA28836.1| (X05204) arom polypeptide
[Emericella nidulans]
Length = 1586
Score = 72.2 bits (174), Expect = 4e-12
Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 23/213 (10%)
Query: 23 SDLYELRADSLKD-------------YSKLELLEP-YSEKLVVTIRSKDEGG-FKELSDE 67
SD ELR D LKD +L L + ++ TIR++ +GG F + + +
Sbjct: 1076 SDAVELRVDLLKDPASNNDIPSVDYVVEQLSFLRSRVTLPIIFTIRTQSQGGRFPDNAHD 1135
Query: 68 KRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVG-SRVILSYHNFR-ETPPFGVLYN 125
LELY +VD++ +D + + + G S++I S+H+ + E + +
Sbjct: 1136 AALELYRLAFRSGCEFVDLDIAFP-EDMLRAVTEMKGFSKIIASHHDPKGELSWANMSWI 1194
Query: 126 LLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFADN-----LIAFCMGSKGKISRIFSS 180
+ E DI+K+V A + DN + + +A LIA MG +G++SRI +
Sbjct: 1195 KFYNKALEYGDIIKLVGVARNIDDNTALRKFKNWAAEAHDVPLIAINMGDQGQLSRILNG 1254
Query: 181 MYSPITYVALDKKAAPGQLTLEELRVILKILGE 213
+P+++ +L KAAPGQL+ E+R L ++GE
Sbjct: 1255 FMTPVSHPSLPFKAAPGQLSATEIRKGLSLMGE 1287
>sp|P05194|AROD_ECOLI 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
>gi|2144535|pir||DWECDQ 3-dehydroquinate dehydratase (EC
4.2.1.10) aroD - Escherichia coli
>gi|40975|emb|CAA42091.1| (X59503) 3-dehydroquinate
dehydratase [Escherichia coli]
>gi|1742757|dbj|BAA15448.1| (D90811) 3-dehydroquinate
dehydratase (EC 4.2.1.10) [Escherichia coli]
>gi|1787984|gb|AAC74763.1| (AE000264) 3-dehydroquinate
dehydratase [Escherichia coli K12]
Length = 252
Score = 72.2 bits (174), Expect = 4e-12
Identities = 65/222 (29%), Positives = 106/222 (47%), Gaps = 21/222 (9%)
Query: 10 SIKEAIEKIKSSSSDLYELRADSLKDYSKLE--------LLEPYSEK-LVVTIRSKDEGG 60
S+K + + D+ E R D D S +E L E EK L+ T RS EGG
Sbjct: 29 SVKSEALAYREADFDILEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGG 88
Query: 61 FKELSDEKRLELYSKFLEIK-PRYVDVEFRS---KIKDEVMEIAKRVGSRVILSYHNFRE 116
+ +S E + L ++ +D+E + ++K E + A +V++S H+F +
Sbjct: 89 EQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVK-ETVAYAHAHDVKVVMSNHDFHK 147
Query: 117 TPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRL-----YEFADN-LIAFCMGS 170
TP + L M+S ADI KI S D + ++ ++AD +I M
Sbjct: 148 TPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAK 207
Query: 171 KGKISRIFSSMY-SPITYVALDKKAAPGQLTLEELRVILKIL 211
G ISR+ ++ S T+ A+ K +APGQ+++ +LR +L IL
Sbjct: 208 TGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTIL 249
>gi|6320332 pentafunctional arom polypeptide (contains: 3-dehydroquinate
synthase, 3-dehydroquinate dehydratase
(3-dehydroquinase), shikimate 5-dehydrogenase, shikimate
kinase, and epsp synthase); Aro1p [Saccharomyces
cerevisiae] >gi|114166|sp|P08566|ARO1_YEAST
PENTAFUNCTIONAL AROM POLYPEPTIDE [INCLUDES:
3-DEHYDROQUINATE SYNTHASE ; 3-DEHYDROQUINATE DEHYDRATASE
(3-DEHYDROQUINASE); SHIKIMATE 5-DEHYDROGENASE ; SHIKIMATE
KINASE ; 3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE
(5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYN>
>gi|66631|pir||BVBYA1 ARO1 protein - yeast (Saccharomyces
cerevisiae) >gi|3381|emb|CAA29458.1| (X06077) arom
multifunctional enzyme (AA 1-1588) [Saccharomyces
cerevisiae] >gi|665659|emb|CAA88208.1| (Z48179) Aro1p
[Saccharomyces cerevisiae]
Length = 1588
Score = 71.8 bits (173), Expect = 6e-12
Identities = 61/206 (29%), Positives = 104/206 (49%), Gaps = 27/206 (13%)
Query: 27 ELRADSLKDYS------KLELLEPYSEKL--VVTIRSKDEGG-FKELSDEKRLELYSKFL 77
E+R D L +YS +L +L ++ + + T+R+ +GG F + + ELY L
Sbjct: 1104 EVRVDHLANYSADFVSKQLSILRKATDSIPIIFTVRTMKQGGNFPDEEFKTLRELYDIAL 1163
Query: 78 EIKPRYVDVEFRSKIKDEVMEIAKRVGSRVILSYHNFRETPPFGVLYNLLEDMESEG--- 134
+ ++D+E + I KR +++I S+H+F+ LY+ +D E E
Sbjct: 1164 KNGVEFLDLELTLPTDIQYEVINKRGNTKIIGSHHDFQG------LYSW-DDAEWENRFN 1216
Query: 135 ------ADIVKIVTHASSPKDNIRIIRLYEFADN--LIAFCMGSKGKISRIFSSMYSPIT 186
D+VK V A + +DN+R+ + N LIA M SKG ISR+ +++ +P+T
Sbjct: 1217 QALTLDVDVVKFVGTAVNFEDNLRLEHFRDTHKNKPLIAVNMTSKGSISRVLNNVLTPVT 1276
Query: 187 YVALDKKAAPGQLTLEELRVILKILG 212
L AAPGQLT+ ++ + +G
Sbjct: 1277 SDLLPNSAAPGQLTVAQINKMYTSMG 1302
>sp|O87007|AROD_SHIDY 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
>gi|3452009|gb|AAC32746.1| (U82269) 3-dehydroquinase
AroD [Shigella dysenteriae]
Length = 252
Score = 71.8 bits (173), Expect = 6e-12
Identities = 64/221 (28%), Positives = 106/221 (47%), Gaps = 21/221 (9%)
Query: 11 IKEAIEKIKSSSSDLYELRADSLKDYSKLE--------LLEPYSEK-LVVTIRSKDEGGF 61
+K + + D+ E R D D S +E L E EK L+ T RS EGG
Sbjct: 30 VKSEALAYRETDFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGE 89
Query: 62 KELSDEKRLELYSKFLEIK-PRYVDVEFRS---KIKDEVMEIAKRVGSRVILSYHNFRET 117
+ +S E + L ++ +D+E + ++K E + A +V++S H+F +T
Sbjct: 90 QAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVK-ETVAYAHAHDVKVVMSNHDFHKT 148
Query: 118 PPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLY-----EFADN-LIAFCMGSK 171
P + L M+S ADI KI S D + ++ ++AD +I M
Sbjct: 149 PEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKT 208
Query: 172 GKISRIFSSMY-SPITYVALDKKAAPGQLTLEELRVILKIL 211
G ISR+ ++ S T+ A+ K +APGQ+++ +LR++L IL
Sbjct: 209 GVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRILLTIL 249
>pir||T50113 pentafunctional enzyme arom [imported] - fission yeast
(Schizosaccharomyces pombe) >gi|7019762|emb|CAB75770.1|
(AL157734) pentafunctional arom polypeptide [includes
3-dehydroquinate synthase](ec 4.6.1.3); 3-dehydroquinate
dehydratase [Schizosaccharomyces pombe]
Length = 1573
Score = 71.8 bits (173), Expect = 6e-12
Identities = 59/212 (27%), Positives = 104/212 (48%), Gaps = 22/212 (10%)
Query: 24 DLYELRADSLKDYSK---LELLEPYSEKL-----------VVTIRSKDEGG-FKELSDEK 68
D E+R D LKD + L+ +E++ + TIR+ +GG F +E+
Sbjct: 1079 DAIEVRVDYLKDPKSSNGISSLDFVAEQISLLRCSTTLPIIFTIRTISQGGLFPNDKEEE 1138
Query: 69 RLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVGSRVILSYHNFRETPPFGVLYNLLE 128
EL + +VDVE + + + +++I+S+H+ T + + ++
Sbjct: 1139 AKELMLSAMRYGCDFVDVELGWSSETINILYQHKGYTKLIMSWHDLSGTWSWARPHEWMQ 1198
Query: 129 DME--SEGADIVKIVTHASSPKDNIRIIRLYEFADN-----LIAFCMGSKGKISRIFSSM 181
+E S AD++K+V A++ DN+ + N LI F MG G++SRI +
Sbjct: 1199 KVELASSYADVIKLVGMANNLNDNLELEEFRTRITNSMDIPLILFNMGRFGQLSRILNKF 1258
Query: 182 YSPITYVALDKKAAPGQLTLEELRVILKILGE 213
+P+T+ L KAAPGQLT+++L ++GE
Sbjct: 1259 MTPVTHPLLPSKAAPGQLTVKQLNEARVLIGE 1290
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.137 0.366
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73464613
Number of Sequences: 2977
Number of extensions: 3042443
Number of successful extensions: 9100
Number of sequences better than 1.0e-10: 19
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 9062
Number of HSP's gapped (non-prelim): 20
length of query: 215
length of database: 189,106,746
effective HSP length: 59
effective length of query: 156
effective length of database: 153,796,013
effective search space: 23992178028
effective search space used: 23992178028
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 163 (67.9 bits)