BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0300 (aroE) DE:shikimate 5-dehydrogenase (aroE)
(264 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75161 shikimate 5-dehydrogenase (aroe) PAB0300 - Pyrococcu... 522 e-147
sp|Q58484|AROE_METJA SHIKIMATE 5-DEHYDROGENASE >gi|2129280|pir||... 244 7e-64
sp|O26344|AROE_METTH SHIKIMATE 5-DEHYDROGENASE 214 1e-54
dbj|BAB05043.1| (AP001511) shikimate 5-dehydrogenase [Bacillus h... 207 9e-53
gi|11499908 shikimate 5-dehydrogenase (aroE) [Archaeoglobus fulg... 196 3e-49
pir||C69130 shikimate 5-dehydrogenase - Methanobacterium thermoa... 193 2e-48
gb|AAG18940.1| (AE004995) shikimate 5-dehydrogenase; AroE [Halob... 187 1e-46
sp|O67049|AROE_AQUAE SHIKIMATE 5-DEHYDROGENASE >gi|7431139|pir||... 186 2e-46
sp|P54374|AROE_BACSU SHIKIMATE 5-DEHYDROGENASE >gi|7431138|pir||... 185 3e-46
gb|AAF08579.1|AC011623_12 (AC011623) putative dehydroquinase shi... 162 4e-39
pir||S46210 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikima... 161 8e-39
sp|P28244|YDIB_ECOLI HYPOTHETICAL 31.2 KDA PROTEIN IN LPP-AROD I... 159 3e-38
pir||T06264 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikima... 157 1e-37
pir||F83615 hypothetical protein PA0244 [imported] - Pseudomonas... 151 9e-36
gb|AAK40643.1| Shikimate 5-dehydrogenase (aroE) [Sulfolobus solf... 148 6e-35
sp|P74591|AROE_SYNY3 SHIKIMATE 5-DEHYDROGENASE >gi|7431136|pir||... 146 3e-34
sp|P15770|AROE_ECOLI SHIKIMATE 5-DEHYDROGENASE >gi|78850|pir||S0... 142 4e-33
pir||C75429 probable shikimate 5-dehydrogenase - Deinococcus rad... 139 4e-32
pir||F82781 shikimate 5-dehydrogenase XF0624 [imported] - Xylell... 133 2e-30
sp|P44774|YDIB_HAEIN HYPOTHETICAL PROTEIN HI0607 >gi|1075301|pir... 132 3e-30
sp|P95368|AROE_NEILA SHIKIMATE 5-DEHYDROGENASE >gi|1785898|gb|AA... 132 5e-30
sp|P95389|AROE_NEIMU SHIKIMATE 5-DEHYDROGENASE >gi|1785908|gb|AA... 132 5e-30
gb|AAC44908.1| (U82837) shikimate dehydrogenase [Neisseria menin... 131 9e-30
gb|AAF71755.1|AF258797_1 (AF258797) shikimate dehydrogenase; Aro... 131 1e-29
sp|P95399|AROE_NEIPO SHIKIMATE 5-DEHYDROGENASE >gi|1785900|gb|AA... 130 2e-29
sp|P95337|AROE_NEICI SHIKIMATE 5-DEHYDROGENASE >gi|1785902|gb|AA... 128 8e-29
sp|P95340|AROE_NEIFL SHIKIMATE 5-DEHYDROGENASE >gi|1785906|gb|AA... 128 8e-29
sp|P95400|AROE_NEIPH SHIKIMATE 5-DEHYDROGENASE >gi|1785904|gb|AA... 127 1e-28
sp|P56992|AROE_NEIMB SHIKIMATE 5-DEHYDROGENASE >gi|11251027|pir|... 126 2e-28
gb|AAC44913.1| (U82842) shikimate dehydrogenase [Neisseria gonor... 126 3e-28
sp|P56991|AROE_NEIMA SHIKIMATE 5-DEHYDROGENASE >gi|11251025|pir|... 126 3e-28
sp|P95361|AROE_NEIGO SHIKIMATE 5-DEHYDROGENASE >gi|1778808|gb|AA... 126 3e-28
sp|Q9WYI1|AROE_THEMA SHIKIMATE 5-DEHYDROGENASE >gi|7431141|pir||... 125 4e-28
gb|AAC44912.1| (U82841) shikimate dehydrogenase [Neisseria menin... 125 7e-28
gb|AAC44906.1| (U82835) shikimate dehydrogenase [Neisseria menin... 124 9e-28
gb|AAC44910.1| (U82839) shikimate dehydrogenase [Neisseria menin... 124 9e-28
gb|AAC44907.1| (U82836) shikimate dehydrogenase [Neisseria menin... 123 2e-27
gb|AAC44905.1| (U82834) shikimate dehydrogenase [Neisseria menin... 123 3e-27
sp|Q9Z6M4|ARDE_CHLPN SHIKIMATE BIOSYNTHESIS PROTEIN ARODE [INCLU... 122 3e-27
gb|AAC44909.1| (U82838) shikimate dehydrogenase [Neisseria menin... 122 4e-27
pir||C81384 shikimate 5-dehydrogenase (EC 1.1.1.25) Cj0405 [impo... 120 1e-26
pir||G82370 shikimate 5-dehydrogenase VC0056 [imported] - Vibrio... 120 1e-26
pir||C75562 probable shikimate 5-dehydrogenase - Deinococcus rad... 119 4e-26
sp|P43876|AROE_HAEIN SHIKIMATE 5-DEHYDROGENASE >gi|1075302|pir||... 115 4e-25
sp|Q9X5C9|AROE_CORGL SHIKIMATE 5-DEHYDROGENASE >gi|4838437|gb|AA... 114 1e-24
emb|CAC11429.1| (AL445063) shikimate 5-dehydrogenase related pro... 114 1e-24
sp|Q9YEK4|Y574_AERPE PUTATIVE SHIKIMATE 5-DEHYDROGENASE-LIKE PRO... 113 3e-24
pir||T50113 pentafunctional enzyme arom [imported] - fission yea... 112 4e-24
pir||G83641 shikimate dehydrogenase PA0025 [imported] - Pseudomo... 107 2e-22
sp|P43904|AROE_PSEAE SHIKIMATE 5-DEHYDROGENASE >gi|747873|emb|CA... 106 3e-22
pir||S52925 shikimate 5-dehydrogenase (EC 1.1.1.25) - Pseudomona... 106 3e-22
sp|Q9ZJX8|AROE_HELPJ SHIKIMATE 5-DEHYDROGENASE >gi|7431143|pir||... 106 4e-22
gi|6320332 pentafunctional arom polypeptide (contains: 3-dehydro... 104 1e-21
sp|P46240|AROE_BUCAP SHIKIMATE 5-DEHYDROGENASE >gi|780130|gb|AAD... 102 3e-21
sp|P56119|AROE_HELPY SHIKIMATE 5-DEHYDROGENASE >gi|7431142|pir||... 102 4e-21
sp|Q44607|AROE_BUCAI SHIKIMATE 5-DEHYDROGENASE >gi|10039152|dbj|... 101 7e-21
sp|Q12659|ARO1_PNECA PENTAFUNCTIONAL AROM POLYPEPTIDE [INCLUDES:... 101 1e-20
sp|P56961|ARDE_CHLMU SHIKIMATE BIOSYNTHESIS PROTEIN ARODE [INCLU... 100 2e-20
emb|CAA13278.1| (AJ232275) shikimate dehydrogenase [Streptococcu... 97 2e-19
emb|CAA13282.1| (AJ232279) shikimate dehydrogenase [Streptococcu... 97 2e-19
emb|CAB60631.1| (AJ252518) shikimate dehydrogenase [Streptococcu... 96 4e-19
emb|CAA13283.1| (AJ232280) shikimate dehydrogenase [Streptococcu... 96 6e-19
emb|CAA13289.1| (AJ232286) shikimate dehydrogenase [Streptococcu... 96 6e-19
emb|CAB60632.1| (AJ252519) shikimate dehydrogenase [Streptococcu... 95 7e-19
emb|CAA13279.1| (AJ232276) shikimate dehydrogenase [Streptococcu... 95 7e-19
emb|CAA13281.1| (AJ232278) shikimate dehydrogenase [Streptococcu... 95 7e-19
emb|CAA13286.1| (AJ232283) shikimate dehydrogenase [Streptococcu... 95 7e-19
emb|CAA13293.1| (AJ232290) shikimate dehydrogenase [Streptococcu... 95 7e-19
emb|CAA13284.1| (AJ232281) shikimate dehydrogenase [Streptococcu... 94 2e-18
sp|O84375|ARDE_CHLTR SHIKIMATE BIOSYNTHESIS PROTEIN ARODE [INCLU... 94 2e-18
emb|CAA13295.1| (AJ232292) shikimate dehydrogenase [Streptococcu... 93 3e-18
gb|AAD28452.1|AF127374_7 (AF127374) MitT [Streptomyces lavendulae] 92 8e-18
emb|CAB76615.1| (AJ271277) shikimate dehydrogenease [Staphylococ... 90 2e-17
emb|CAB76612.1| (AJ271274) shikimate dehydrogenease [Staphylococ... 90 3e-17
emb|CAB76616.1| (AJ271278) shikimate dehydrogenease [Staphylococ... 90 3e-17
emb|CAB76620.1| (AJ271283) shikimate dehydrogenease [Staphylococ... 90 3e-17
emb|CAB76626.1| (AJ271289) shikimate dehydrogenease [Staphylococ... 90 3e-17
emb|CAB76613.1| (AJ271275) shikimate dehydrogenease [Staphylococ... 89 5e-17
emb|CAB76614.1| (AJ271276) shikimate dehydrogenease [Staphylococ... 89 5e-17
emb|CAB76619.1| (AJ271281) shikimate dehydrogenease [Staphylococ... 89 5e-17
emb|CAA13280.1| (AJ232277) shikimate dehydrogenase [Streptococcu... 89 7e-17
emb|CAB76625.1| (AJ271288) shikimate dehydrogenease [Staphylococ... 89 7e-17
emb|CAB76611.1| (AJ271273) shikimate dehydrogenase [Staphylococc... 87 2e-16
emb|CAB76622.1| (AJ271285) shikimate dehydrogenease [Staphylococ... 87 2e-16
emb|CAB76621.1| (AJ271284) shikimate dehydrogenease [Staphylococ... 87 3e-16
pir||D70660 probable aroE - Mycobacterium tuberculosis (strain H... 86 5e-16
gb|AAC08642.1| (AF037792) shikimate dehydrogenase [Neisseria men... 83 2e-15
gb|AAC08635.1| (AF037785) shikimate dehydrogenase [Neisseria men... 82 5e-15
gb|AAC08640.1| (AF037790) shikimate dehydrogenase [Neisseria men... 82 5e-15
gb|AAC08647.1| (AF037797) shikimate dehydrogenase [Neisseria men... 81 1e-14
sp|P25415|DHQA_EMENI QUINATE 5-DEHYDROGENASE >gi|2401|emb|CAA318... 81 2e-14
pir||S08499 quinate 5-dehydrogenase (EC 1.1.1.24) - Emericella n... 81 2e-14
gb|AAC01719.1| (AF040570) aminoquinate/shkimate dehydrogenase [A... 81 2e-14
gb|AAF97082.1|AF267542_1 (AF267542) shikimate dehydrogenase [Esc... 80 2e-14
gb|AAF97084.1|AF267544_1 (AF267544) shikimate dehydrogenase [Esc... 79 6e-14
gb|AAF97086.1|AF267546_1 (AF267546) shikimate dehydrogenase [Esc... 79 6e-14
gb|AAC08646.1| (AF037796) shikimate dehydrogenase [Neisseria men... 78 8e-14
gb|AAF97088.1|AF267548_1 (AF267548) shikimate dehydrogenase [Esc... 78 8e-14
gb|AAF97098.1|AF267558_1 (AF267558) shikimate dehydrogenase [Esc... 78 8e-14
sp|P07547|ARO1_EMENI PENTAFUNCTIONAL AROM POLYPEPTIDE [INCLUDES:... 78 1e-13
gb|AAF97087.1|AF267547_1 (AF267547) shikimate dehydrogenase [Esc... 77 2e-13
gb|AAC08636.1| (AF037786) shikimate dehydrogenase [Neisseria men... 76 3e-13
gb|AAC08641.1| (AF037791) shikimate dehydrogenase [Neisseria men... 76 3e-13
gb|AAC08630.1| (AF037780) shikimate dehydrogenase [Neisseria men... 76 4e-13
gb|AAC08639.1| (AF037789) shikimate dehydrogenase [Neisseria men... 76 5e-13
gb|AAC08644.1| (AF037794) shikimate dehydrogenase [Neisseria men... 75 7e-13
gb|AAF97079.1|AF267539_1 (AF267539) shikimate dehydrogenase [Esc... 75 9e-13
gb|AAF97091.1|AF267551_1 (AF267551) shikimate dehydrogenase [Esc... 75 9e-13
gb|AAC08631.1| (AF037781) shikimate dehydrogenase [Neisseria men... 74 2e-12
gb|AAC08632.1| (AF037782) shikimate dehydrogenase [Neisseria men... 74 2e-12
gb|AAC08633.1| (AF037783) shikimate dehydrogenase [Neisseria men... 74 2e-12
gb|AAD50802.1| (AF165316) shikimate dehydrogenase [Neisseria men... 74 2e-12
gb|AAD31827.1| (AF131877) shikimate/quinate dehydrogenase [Strep... 74 2e-12
gb|AAF97090.1|AF267550_1 (AF267550) shikimate dehydrogenase [Esc... 74 2e-12
pir||S48698 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikima... 73 4e-12
gb|AAC08638.1| (AF037788) shikimate dehydrogenase [Neisseria men... 72 6e-12
emb|CAB93378.1| (AL357523) shikimate 5-dehydrogenase [Streptomyc... 70 3e-11
>pir||E75161 shikimate 5-dehydrogenase (aroe) PAB0300 - Pyrococcus abyssi
(strain Orsay) >gi|5457882|emb|CAB49372.1| (AJ248284)
shikimate 5-dehydrogenase (aroE) [Pyrococcus abyssi]
Length = 264
Score = 522 bits (1330), Expect = e-147
Identities = 264/264 (100%), Positives = 264/264 (100%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTM 60
MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTM
Sbjct: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTM 60
Query: 61 PYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNVLI 120
PYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNVLI
Sbjct: 61 PYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNVLI 120
Query: 121 LGAGGAGKAIAYELSKIANIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGWADVLINAT 180
LGAGGAGKAIAYELSKIANIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGWADVLINAT
Sbjct: 121 LGAGGAGKAIAYELSKIANIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGWADVLINAT 180
Query: 181 SVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQGAESF 240
SVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQGAESF
Sbjct: 181 SVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQGAESF 240
Query: 241 KLWTGIYPDVELMRRVSLERLGKG 264
KLWTGIYPDVELMRRVSLERLGKG
Sbjct: 241 KLWTGIYPDVELMRRVSLERLGKG 264
>sp|Q58484|AROE_METJA SHIKIMATE 5-DEHYDROGENASE >gi|2129280|pir||C64435 shikimate
5-dehydrogenase (EC 1.1.1.25) - Methanococcus jannaschii
>gi|1591730|gb|AAB99086.1| (U67551) shikimate
5-dehydrogenase (aroE) [Methanococcus jannaschii]
Length = 282
Score = 244 bits (617), Expect = 7e-64
Identities = 132/279 (47%), Positives = 189/279 (67%), Gaps = 20/279 (7%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVT 59
KV GLIG PV HS SP+MHNA F+ G++ VYV F+V E L IDG +ALGI G NVT
Sbjct: 7 KVIGLIGHPVEHSFSPIMHNAAFKDKGLNYVYVAFDVLPENLKYVIDGAKALGIVGFNVT 66
Query: 60 MPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNV 118
+P+K + K+LDE+ +DA+ I +VNTI +G IGY TDG+GAR ALE ++ +N+
Sbjct: 67 IPHKIEIMKYLDEIDKDAQLIGAVNTIKIEDGKAIGYNTDGIGARMALEEEIGRVKDKNI 126
Query: 119 LILGAGGAGKAIAYELSKIANIVVLNRTPSKAKSL---------EKFG--VKGGSLDELP 167
+I GAGGA +A+A+EL+K NI++ NRT KA++L +KFG VK LD
Sbjct: 127 VIYGAGGAARAVAFELAKDNNIIIANRTVEKAEALAKEIAEKLNKKFGEEVKFSGLDVDL 186
Query: 168 NYVGWADVLINATSVGMGTN---ESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR 224
+ V D++INAT +GM N E +V LR +++VMD++Y PL+T LL++A+ V +
Sbjct: 187 DGV---DIIINATPIGMYPNIDVEPIVKAEKLREDMVVMDLIYNPLETVLLKEAKKVNAK 243
Query: 225 VIDGLWMLIYQGAESFKLWTGIYPDVELMRRVSLERLGK 263
I+GL MLIYQGA +FK+WTG+ P++E+M+ ++++ K
Sbjct: 244 TINGLGMLIYQGAVAFKIWTGVEPNIEVMKNAIIDKITK 282
>sp|O26344|AROE_METTH SHIKIMATE 5-DEHYDROGENASE
Length = 283
Score = 214 bits (539), Expect = 1e-54
Identities = 116/265 (43%), Positives = 172/265 (64%), Gaps = 14/265 (5%)
Query: 3 VYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVTM 60
V G++G P+ HSLSP+MHNA FR G+D +YV F V E L A++G+RALG+ G+NVT+
Sbjct: 8 VTGIMGHPLGHSLSPIMHNAAFRSLGMDWIYVPFPVKPENLKAAVEGLRALGVEGVNVTI 67
Query: 61 PYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNVLI 120
P+KE V +++D++ A I +VNT+ +G++ GY TD G +ALE T +EG +VLI
Sbjct: 68 PHKEAVLEYIDDIHGTAALIGAVNTLKFDDGTVRGYNTDASGCLRALEEVTSVEGSSVLI 127
Query: 121 LGAGGAGKAIAYELSK--IANIVVLNRTPSKAKSL-----EKFGVKG--GSLDELPNYVG 171
LGAGGA +A A++L++ ++I +LNRTP KA+ L +K G + G + + V
Sbjct: 128 LGAGGAARACAFQLAEKGASDITILNRTPEKARLLAEDMADKLGFEASYGGYELIQGSVK 187
Query: 172 WADVLINATSVGM---GTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDG 228
AD+LI+ T VGM + LV L+ L+V D+VY P +T LLR+AE + G
Sbjct: 188 SADILIDTTPVGMHPHTDDRPLVGAELMHEGLVVHDLVYNPQRTVLLREAERASAIPVSG 247
Query: 229 LWMLIYQGAESFKLWTGIYPDVELM 253
+ ML+YQG E+F++WTG P +++M
Sbjct: 248 IRMLLYQGVEAFRIWTGRDPPLDVM 272
>dbj|BAB05043.1| (AP001511) shikimate 5-dehydrogenase [Bacillus halodurans]
Length = 278
Score = 207 bits (522), Expect = 9e-53
Identities = 117/275 (42%), Positives = 168/275 (60%), Gaps = 14/275 (5%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVE--ELGKAIDGVRALGISGLNVT 59
K++GL+G PV HSLSP+MHN +F+ D Y F+VE +L KA++G RAL + G NVT
Sbjct: 3 KLFGLLGHPVGHSLSPLMHNQMFQLLDFDGYYHAFDVEPSQLEKAVEGARALQMQGFNVT 62
Query: 60 MPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERF--TEIEGRN 117
+P+K + +LD + E+A+EI +VNT++ +G L G TDG G ++L T ++
Sbjct: 63 IPHKVTIMDYLDMVDEEAQEIGAVNTVVMKDGQLFGSNTDGQGYLESLMDVVTTPFPTQD 122
Query: 118 VLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLE------KFGVKGGSLDELPNY 169
VLI+GAGGA +AI L K+ +I + NRT +KA+ + SL E
Sbjct: 123 VLIIGAGGAARAIGTVLKREKVRSITIANRTLAKAEEFSGVLESSETSCSALSLKEAEQQ 182
Query: 170 VGWADVLINATSVGMGTNESLVPRRL--LRRELIVMDIVYKPLKTRLLRDAESVGCRVID 227
+ V+IN TSVGM +P L L RE +V D++Y PL+T+ LR+A+ G + +D
Sbjct: 183 LERFSVIINTTSVGMSPRVDDMPLSLERLSRETVVSDLIYNPLETKFLREAKQKGAKTVD 242
Query: 228 GLWMLIYQGAESFKLWTGIYPDVELMRRVSLERLG 262
GL M + QGA +F+LWTG+ PD E MRR LE+LG
Sbjct: 243 GLGMFVNQGALAFELWTGLRPDREKMRRCVLEQLG 277
>gi|11499908 shikimate 5-dehydrogenase (aroE) [Archaeoglobus fulgidus]
>gi|9087116|sp|O27957|AROE_ARCFU SHIKIMATE
5-DEHYDROGENASE >gi|7431135|pir||G69540 shikimate
5-dehydrogenase (aroE) homolog - Archaeoglobus fulgidus
>gi|2648193|gb|AAB88930.1| (AE000944) shikimate
5-dehydrogenase (aroE) [Archaeoglobus fulgidus]
Length = 269
Score = 196 bits (492), Expect = 3e-49
Identities = 114/271 (42%), Positives = 168/271 (61%), Gaps = 14/271 (5%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNV 58
M G+IG P+ HS+SP MHNA + GI+ +Y+ FEV + L A+ G +ALG GLNV
Sbjct: 1 MLYLGVIGYPIKHSVSPAMHNAALQHEGIEGIYLAFEVKPDRLRDAVFGAKALGFRGLNV 60
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNV 118
T+P+KE V +F+ EL +A +I +VNTI +E ++GY TD G + AL TE+ G+
Sbjct: 61 TIPFKESVVEFV-ELEGEAAKIKTVNTIDLVE--MVGYNTDVYGVKAALSG-TELGGKTA 116
Query: 119 LILGAGGAGKAIAYELSKIAN-IVVLNRTPSKAKSLEKFGVKGGS-----LDELPNYVGW 172
L++GAGGAGKA A L + + ++V NRT K + + + G L + G
Sbjct: 117 LVVGAGGAGKAAALALLDMGSTVIVANRTEEKGREAVEMLRRYGECIFWPLSRVEELKGK 176
Query: 173 ADVLINATSVGMG--TNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLW 230
DV++NAT +GM E VP +L +V D VY P++T L+R+A+ GC+V+ G+
Sbjct: 177 VDVVVNATPLGMRGFKAEIPVPPSMLDGVELVFDTVYNPMETPLIREAKKRGCKVVYGIE 236
Query: 231 MLIYQGAESFKLWTGIYPDVELMRRVSLERL 261
ML++QGA++F++WTGI PDV +MR +L L
Sbjct: 237 MLVHQGAKAFEIWTGIEPDVGVMREAALRAL 267
>pir||C69130 shikimate 5-dehydrogenase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621291|gb|AAB84748.1| (AE000811)
shikimate 5-dehydrogenase [Methanobacterium
thermoautotrophicum]
Length = 260
Score = 193 bits (485), Expect = 2e-48
Identities = 107/249 (42%), Positives = 159/249 (62%), Gaps = 14/249 (5%)
Query: 19 MHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSED 76
MHNA FR G+D +YV F V E L A++G+RALG+ G+NVT+P+KE V +++D++
Sbjct: 1 MHNAAFRSLGMDWIYVPFPVKPENLKAAVEGLRALGVEGVNVTIPHKEAVLEYIDDIHGT 60
Query: 77 AREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYELSK 136
A I +VNT+ +G++ GY TD G +ALE T +EG +VLILGAGGA +A A++L++
Sbjct: 61 AALIGAVNTLKFDDGTVRGYNTDASGCLRALEEVTSVEGSSVLILGAGGAARACAFQLAE 120
Query: 137 --IANIVVLNRTPSKAKSL-----EKFGVKG--GSLDELPNYVGWADVLINATSVGM--- 184
++I +LNRTP KA+ L +K G + G + + V AD+LI+ T VGM
Sbjct: 121 KGASDITILNRTPEKARLLAEDMADKLGFEASYGGYELIQGSVKSADILIDTTPVGMHPH 180
Query: 185 GTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQGAESFKLWT 244
+ LV L+ L+V D+VY P +T LLR+AE + G+ ML+YQG E+F++WT
Sbjct: 181 TDDRPLVGAELMHEGLVVHDLVYNPQRTVLLREAERASAIPVSGIRMLLYQGVEAFRIWT 240
Query: 245 GIYPDVELM 253
G P +++M
Sbjct: 241 GRDPPLDVM 249
>gb|AAG18940.1| (AE004995) shikimate 5-dehydrogenase; AroE [Halobacterium sp.
NRC-1]
Length = 266
Score = 187 bits (470), Expect = 1e-46
Identities = 115/267 (43%), Positives = 156/267 (58%), Gaps = 7/267 (2%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNV 58
M VYGLIG PV HSLSP +H A + + G+DA YVTFE ++ AI G ALG++GLNV
Sbjct: 1 MDVYGLIGNPVGHSLSPPLHAAAYDECGLDARYVTFEPAPDDAAAAIRGAGALGVAGLNV 60
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERF-TEIEGRN 117
T P+K+ + S AR + +VNTI + GY TD G ++A + G
Sbjct: 61 TAPFKQSAASAVATDSMAAR-VGAVNTIDFSGAAPRGYNTDVAGVKRAFAHHDVSLSGAQ 119
Query: 118 VLILGAGGAGKAIAYELSKI-ANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADV 175
+++GAGGAG+A A+ L+ A + + NRT + A L G L +LP + A V
Sbjct: 120 AVVVGAGGAGRAAAFALADAGATVRIANRTRAAADELAADVGGTAVGLGDLPRSLADATV 179
Query: 176 LINATSVGMGTNE-SLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIY 234
L++AT+VGM + S V L +L V+D VY P++TRLLRDA + G IDG WML+Y
Sbjct: 180 LVHATTVGMDDPDTSPVSADALHDDLAVLDAVYSPVETRLLRDAAAAGATTIDGAWMLLY 239
Query: 235 QGAESFKLWTGIYPDVELMRRVSLERL 261
QGAE+F+ WTG+ V MR RL
Sbjct: 240 QGAEAFERWTGLDAPVAAMRAALRARL 266
>sp|O67049|AROE_AQUAE SHIKIMATE 5-DEHYDROGENASE >gi|7431139|pir||F70377 shikimate
5-dehydrogenase - Aquifex aeolicus
>gi|2983425|gb|AAC07007.1| (AE000713) shikimate
5-dehydrogenase [Aquifex aeolicus]
Length = 269
Score = 186 bits (468), Expect = 2e-46
Identities = 104/250 (41%), Positives = 163/250 (64%), Gaps = 10/250 (4%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVT 59
++YG+IG PV HSLSPV NAL R G++AVY+ FE+ EEL KA +G +AL + G+NVT
Sbjct: 7 QLYGVIGFPVKHSLSPVFQNALIRYAGLNAVYLAFEINPEELKKAFEGFKALKVKGINVT 66
Query: 60 MPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNV 118
+P+KE + LD + + A+EI +VNT+ G GY TD +G K+L+ E++ +++
Sbjct: 67 VPFKEEIIPLLDYVEDTAKEIGAVNTVKFENGKAYGYNTDWIGFLKSLKSLIPEVKEKSI 126
Query: 119 LILGAGGAGKAIAYELSKI-ANIVVLNRTPSKA-KSLEKFGVKGGSLDELPNYVGWADVL 176
L+LGAGGA +A+ Y L K A + + NRT KA K +KF ++ + E + V+
Sbjct: 127 LVLGAGGASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPE--EVIDKVQVI 184
Query: 177 INATSVGMGTNE-SLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQ 235
+N TSVG+ + + L++++ +V+DI+YK +T+LL+ A+ G ++ DGL ML++Q
Sbjct: 185 VNTTSVGLKDKDPEIFNYDLIKKDHVVVDIIYK--ETKLLKKAKEKGAKLFDGLPMLLWQ 242
Query: 236 GAESFKLWTG 245
G E+FK+W G
Sbjct: 243 GIEAFKIWNG 252
>sp|P54374|AROE_BACSU SHIKIMATE 5-DEHYDROGENASE >gi|7431138|pir||A69590 shikimate
5-dehydrogenase aroD - Bacillus subtilis
>gi|1303789|dbj|BAA12445.1| (D84432) AroD [Bacillus
subtilis] >gi|2635012|emb|CAB14508.1| (Z99117) shikimate
5-dehydrogenase [Bacillus subtilis]
Length = 280
Score = 185 bits (466), Expect = 3e-46
Identities = 108/274 (39%), Positives = 161/274 (58%), Gaps = 13/274 (4%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEE--LGKAIDGVRALGISGLNVT 59
K+YG+IG P+ HS+SP +HNA + G+D Y F+VEE L A+ G+RALG+ G+NVT
Sbjct: 3 KLYGVIGNPIGHSMSPDIHNASLKDLGLDGHYHAFKVEENDLEDAVKGIRALGVQGINVT 62
Query: 60 MPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTE--IEGRN 117
+P+K + +LD + E A+ + +VNT+ L+GY TDG G K+L + + I +
Sbjct: 63 VPHKVSIMDYLDHIDESAKVLGAVNTVRREGDKLVGYNTDGEGFVKSLMKVLDKPISELS 122
Query: 118 VLILGAGGAGKAI--AYELSKIANIVVLNRTPSKAKSLEK-----FGVKGGSLDELPNYV 170
L++GAGGA +AI + + + NRT KAK L + + S+ E +
Sbjct: 123 FLMIGAGGAARAIFTTFVRNTPKKFDICNRTLEKAKRLTEATPSFHNKEVLSIKEAEERL 182
Query: 171 GWADVLINATSVGMGTNESLVPRRLLR--RELIVMDIVYKPLKTRLLRDAESVGCRVIDG 228
DV+I+ TSVGM N VP L R +V DIVY P++T LL++A G + +DG
Sbjct: 183 EQYDVIIHTTSVGMYPNVDDVPLSLQRAASSAVVCDIVYNPIQTALLKEASQKGLKTLDG 242
Query: 229 LWMLIYQGAESFKLWTGIYPDVELMRRVSLERLG 262
+ M + Q A SF+LWTG P++E MR + + +LG
Sbjct: 243 VGMFVEQAALSFQLWTGQEPNIEKMRSIVIGKLG 276
>gb|AAF08579.1|AC011623_12 (AC011623) putative dehydroquinase shikimate dehydrogenase
[Arabidopsis thaliana]
Length = 603
Score = 162 bits (406), Expect = 4e-39
Identities = 103/272 (37%), Positives = 149/272 (53%), Gaps = 21/272 (7%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMP 61
KVYG+IGKPVSHS SP++HN F+ + VYV V+ L + + +G + T+P
Sbjct: 324 KVYGIIGKPVSHSKSPIVHNQAFKSVDFNGVYVHLLVDNLVSFLQAYSSSDFAGFSCTIP 383
Query: 62 YKEVVTKFLDELSEDAREINSVNTII--NLEGSLIGYTTDGVGARKALE----------- 108
+KE + DE+ A+ I +VNTI+ +G L+GY TD +G+ A+E
Sbjct: 384 HKEAALQCCDEVDPLAKSIGAVNTILRRKSDGKLLGYNTDCIGSISAIEDGLRSSGDPSS 443
Query: 109 ---RFTEIEGRNVLILGAGGAGKAIAY-ELSKIANIVVLNRTPSKAKSL-EKFGVKGGSL 163
+ + + V+++GAGGAGKA+AY K A +V+ NRT +A L E G K SL
Sbjct: 444 VPSSSSPLASKTVVVIGAGGAGKALAYGAKEKGAKVVIANRTYERALELAEAIGGKALSL 503
Query: 164 DELPNY-VGWADVLINATSVGMGTN--ESLVPRRLLRRELIVMDIVYKPLKTRLLRDAES 220
+L NY VL N TS+GM N E+ + + L+ +V D VY P TRLLR+AE
Sbjct: 504 TDLDNYHPEDGMVLANTTSMGMQPNVEETPISKDALKHYALVFDAVYTPRITRLLREAEE 563
Query: 221 VGCRVIDGLWMLIYQGAESFKLWTGIYPDVEL 252
G + G M + Q E F+++TG+ EL
Sbjct: 564 SGAITVSGSEMFVRQAYEQFEIFTGLPAPKEL 595
>pir||S46210 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikimate
5-dehydrogenase (EC 1.1.1.25) precursor - common tobacco
(fragment) >gi|535771|gb|AAA34069.1| (L32794)
dehydroquinate dehydratase/shikimate dehydrogenase
[Nicotiana tabacum]
Length = 579
Score = 161 bits (403), Expect = 8e-39
Identities = 97/261 (37%), Positives = 153/261 (58%), Gaps = 16/261 (6%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMP 61
+++G+IGKPVSHS SP+++N FR G + VY+ V+++ +L +G VT+P
Sbjct: 262 RIFGIIGKPVSHSKSPLLYNEAFRSVGFNGVYMPLLVDDVANFFRTYSSLDFAGSAVTIP 321
Query: 62 YKEVVTKFLDELSEDAREINSVNTIIN-LEGSLIGYTTDGVGARKALERFTE-------- 112
+KE + DEL+ A+ I +VN +++ L+G L G TD VGA A+E +
Sbjct: 322 HKEAIVDCCDELNPTAKVIGAVNCVVSRLDGKLFGCNTDYVGAISAIEEALQGSQPSMSG 381
Query: 113 --IEGRNVLILGAGGAGKAIAY-ELSKIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPN 168
+ G+ +++GAGGAGKA+AY K A +V+ NRT +A+ L + G + SLDEL N
Sbjct: 382 SPLAGKLFVVIGAGGAGKALAYGAKEKGARVVIANRTYERARELADVVGGQALSLDELSN 441
Query: 169 YVGWAD-VLINATSVGM--GTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRV 225
+ D +L N TS+GM +++ + + LR +V D VY P TRLLR+A G ++
Sbjct: 442 FHPENDMILANTTSIGMQPKVDDTPIFKEALRYYSLVFDAVYTPKITRLLREAHESGVKI 501
Query: 226 IDGLWMLIYQGAESFKLWTGI 246
+ G+ M I Q E ++ +TG+
Sbjct: 502 VTGVEMFIGQAYEQYERFTGL 522
>sp|P28244|YDIB_ECOLI HYPOTHETICAL 31.2 KDA PROTEIN IN LPP-AROD INTERGENIC REGION
>gi|7431137|pir||D64927 probable shikimate
5-dehydrogenase (EC 1.1.1.25) ydiB - Escherichia coli
>gi|1742758|dbj|BAA15449.1| (D90811) Shikimate
5-dehydrogenase (EC 1.1.1.25). [Escherichia coli]
>gi|1787983|gb|AAC74762.1| (AE000264) putative
oxidoreductase [Escherichia coli K12]
Length = 288
Score = 159 bits (398), Expect = 3e-38
Identities = 101/276 (36%), Positives = 156/276 (55%), Gaps = 21/276 (7%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEE--LGKAIDGVRALGISGLNVT 59
++ GL+ P+ HSLSP M N K G+ Y+ FEV+ AI+G++AL + G V+
Sbjct: 8 ELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPGAIEGLKALKMRGTGVS 67
Query: 60 MPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKAL-ERFTEIEGRNV 118
MP K++ +++DEL+ A+ + ++NTI+N +G L GY TDG G +A+ E +I+G+ +
Sbjct: 68 MPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTM 127
Query: 119 LILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKSLEKFGVKGG-------SLDELPNY 169
++LGAGGA AI + + + I + NR F + ++ +L +
Sbjct: 128 VLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEFFDKALAFAQRVNENTDCVVTVTDLADQ 187
Query: 170 VGW------ADVLINATSVGMG--TNESLV-PRRLLRRELIVMDIVYKPLKTRLLRDAES 220
+ AD+L N T VGM NESLV LL L+V + VY P T+LL+ A+
Sbjct: 188 QAFAEALASADILTNGTKVGMKPLENESLVNDISLLHPGLLVTECVYNPHMTKLLQQAQQ 247
Query: 221 VGCRVIDGLWMLIYQGAESFKLWTGIYPDVELMRRV 256
GC+ IDG ML++QGAE F LWTG +E +++V
Sbjct: 248 AGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQV 283
>pir||T06264 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikimate
5-dehydrogenase (EC 1.1.1.25) - tomato
>gi|3169883|gb|AAC17991.1| (AF033194) dehydroquinate
dehydratase/shikimate:NADP oxidoreductase [Lycopersicon
esculentum] >gi|3169888|gb|AAC17993.1| (AF034411)
dehydroquinate dehydratase/shikimate:NADP oxidoreductase
[Lycopersicon esculentum]
Length = 545
Score = 157 bits (394), Expect = 1e-37
Identities = 96/271 (35%), Positives = 152/271 (55%), Gaps = 16/271 (5%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMP 61
K++G+IGKPVSHS SP+++N FR G + V++ V+++ +L +G + T+P
Sbjct: 271 KIFGIIGKPVSHSKSPLLYNESFRSVGFNGVFMHLLVDDIANFFRTYSSLDFAGFSCTIP 330
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINL-EGSLIGYTTDGVGARKALERFTE-------- 112
+KE E+ A+ I +VN II +G L G TD +GA A+E +
Sbjct: 331 HKEAALDCCAEIDPTAKAIGAVNCIIRRPDGKLFGCNTDYIGAISAIEEGLQGSQPSISG 390
Query: 113 --IEGRNVLILGAGGAGKAIAY-ELSKIANIVVLNRTPSKAKSLE-KFGVKGGSLDELPN 168
+ G+ +++GAGGAGKAIAY K A +V+ NRT +A+ L G + SLDEL N
Sbjct: 391 SPLAGKLFVVIGAGGAGKAIAYGAKEKGARVVIANRTYERARELAIVVGAEALSLDELSN 450
Query: 169 YVGWAD-VLINATSVGM--GTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRV 225
+ D +L N TS+GM +++ + + L+ +V D VY P TRLLR+A+ G ++
Sbjct: 451 FHPENDMILANTTSIGMQPKVDDTPISKEALKHYSLVFDAVYTPKITRLLREAQESGAKI 510
Query: 226 IDGLWMLIYQGAESFKLWTGIYPDVELMRRV 256
+ G+ M I Q E ++ +TG+ EL + +
Sbjct: 511 VTGVEMFIGQAYEQYERFTGLPAPKELFKNI 541
>pir||F83615 hypothetical protein PA0244 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9946083|gb|AAG03633.1|AE004462_6
(AE004462) hypothetical protein [Pseudomonas aeruginosa]
Length = 284
Score = 151 bits (377), Expect = 9e-36
Identities = 92/267 (34%), Positives = 151/267 (56%), Gaps = 17/267 (6%)
Query: 5 GLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRAL-------GISGLN 57
GLIG + S +P +H GI +Y +++ LGK+ D + L G +GLN
Sbjct: 10 GLIGAGIQASRTPALHEREGDAQGIRYLYRLIDLDPLGKSADDLEFLLAAASDLGFTGLN 69
Query: 58 VTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGR 116
VT P K+ + LD+LS +AR I +VNT++ +G IG+ TD +G + R + +
Sbjct: 70 VTFPCKQAIIPLLDDLSAEARGIGAVNTVVLRDGRRIGHNTDCLGFAEGFRRGLADAPRQ 129
Query: 117 NVLILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSL-----EKFGV-KGGSLDELPN 168
V+ +GAGGAG A+A+ L + +V+ + P++A++L + FG + + +L
Sbjct: 130 RVVQMGAGGAGAAVAHALLAEGVERLVLFDVDPARAQALADNLNQHFGAPRALAGSDLAG 189
Query: 169 YVGWADVLINATSVGMGTNESL-VPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVID 227
+G A L+N T VGM + VP LLR +L V +++Y PL+T LLR A ++GCR +D
Sbjct: 190 ALGDAQGLVNTTPVGMAKLPGMPVPAELLRADLWVAEVIYFPLETELLRQARALGCRTLD 249
Query: 228 GLWMLIYQGAESFKLWTGIYPDVELMR 254
G M ++Q ++F+L++G+ D M+
Sbjct: 250 GGTMAVFQAVKAFELFSGVTADAARMQ 276
>gb|AAK40643.1| Shikimate 5-dehydrogenase (aroE) [Sulfolobus solfataricus]
Length = 269
Score = 148 bits (370), Expect = 6e-35
Identities = 86/247 (34%), Positives = 145/247 (57%), Gaps = 13/247 (5%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELG--KAIDGVRALGISGLNVT 59
K++GLIGK + ++LSP +HN FR GI+AVY+ F+++E+ ++I G+ + GLNVT
Sbjct: 10 KLFGLIGKNIKYTLSPYIHNFSFRTLGINAVYLVFDLDEMKFKRSISGILEIA-EGLNVT 68
Query: 60 MPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKAL-ERFTEIEGRNV 118
+PYK+ V K+LD + I +VNTI G Y TD + + + ++ + G
Sbjct: 69 IPYKDEVMKYLDNTDTHSTRIQAVNTIYKKSG----YNTDYLAIKNLVRKKIKNVSGYEC 124
Query: 119 LILGAGGAGKAIAYELSKI--ANIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGWADVL 176
I GAGGA KA A+ LS++ ++I ++NRT S+A L + K G + ++
Sbjct: 125 YIYGAGGAAKAAAFALSELGCSSISIVNRTKSRAYELAELLNKNGYNASIKEN---CNIT 181
Query: 177 INATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQG 236
N V N S+VP +++ +V++ VY+P++T L+++A+ G + I+GL +L+ Q
Sbjct: 182 NNILIVNSTPNSSVVPEDCVKKSDLVIEFVYRPVETELIKNAKKYGIQYINGLEILVNQA 241
Query: 237 AESFKLW 243
E+ K+W
Sbjct: 242 VEAEKIW 248
>sp|P74591|AROE_SYNY3 SHIKIMATE 5-DEHYDROGENASE >gi|7431136|pir||S76787 hypothetical
protein - Synechocystis sp. (strain PCC 6803)
>gi|1653788|dbj|BAA18699.1| (D90916) shikimate
5-dehydrogenase [Synechocystis sp.]
Length = 290
Score = 146 bits (364), Expect = 3e-34
Identities = 101/282 (35%), Positives = 148/282 (51%), Gaps = 22/282 (7%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVT 59
K+ G+IG PV HSLSPVMHNA + D YV F + E+L AI G+ A G+ GL+VT
Sbjct: 9 KLLGVIGYPVGHSLSPVMHNAALQAMASDYAYVAFPIAPEDLTIAIAGLGASGVQGLSVT 68
Query: 60 MPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVG-ARKALERFTEIEGRNV 118
+P+K+VV L +++E AR++ +VNT+ G TD G LE + GR
Sbjct: 69 IPHKQVVMPLLTQITETARQVGAVNTLWRDGHGWQGTNTDVEGFLAPLLELKQDWSGRTA 128
Query: 119 LILGAGGAGKAIAYELSKIA--NIVVLNRTPSKAKSLE--------KFGVKGGSLDELPN 168
+ILG GGA +A+ L+++ I+V+ R+ K K ++ + L
Sbjct: 129 VILGYGGAARAVVVGLTQLGCPEIIVVGRSQEKLAQFANSWTDPKIKQALQVLPWEALST 188
Query: 169 YVGWADVLINATSVGMGTN-------ESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESV 221
+ A +LIN+T VGM + +SLV + L I D++Y P TR L+ A+
Sbjct: 189 VIPKASLLINSTPVGMAPHPKQSPLDQSLVEK--LPPTAIAYDLIYTPRPTRFLQHAQER 246
Query: 222 GCRVIDGLWMLIYQGAESFKLWTGIYPDVELMRRVSLERLGK 263
G IDG ML+ QGA + K+W V++MR+ L L K
Sbjct: 247 GLVTIDGAEMLVQQGAAALKIWLQQEVPVDVMRQALLHHLEK 288
>sp|P15770|AROE_ECOLI SHIKIMATE 5-DEHYDROGENASE >gi|78850|pir||S00252 shikimate
5-dehydrogenase (EC 1.1.1.25) - Escherichia coli
>gi|40978|emb|CAA68700.1| (Y00710) shikimate
dehydrogenase [Escherichia coli]
>gi|606215|gb|AAA58078.1| (U18997) shikimate
dehydrogenase [Escherichia coli]
>gi|1789675|gb|AAC76306.1| (AE000406) dehydroshikimate
reductase [Escherichia coli K12]
Length = 272
Score = 142 bits (355), Expect = 4e-33
Identities = 94/262 (35%), Positives = 139/262 (52%), Gaps = 13/262 (4%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNV 58
M+ Y + G P++HS SP +H ++ I+ Y V + + ++ + G G NV
Sbjct: 1 METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFSAGGKGANV 60
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GR 116
T+P+KE DEL+E A +VNT++ LE G L+G TDGVG LER + I G
Sbjct: 61 TVPFKEEAFARADELTERAALAGAVNTLMRLEDGRLLGDNTDGVGLLSDLERLSFIRPGL 120
Query: 117 NVLILGAGGAGKAIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYV 170
+L++GAGGA + + L + + + NRT S+A+ L K GS+ DEL +
Sbjct: 121 RILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALSMDELEGHE 180
Query: 171 GWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDGL 229
D++INATS G+ + +P L+ + D+ Y+ KT L E G R DGL
Sbjct: 181 --FDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGL 238
Query: 230 WMLIYQGAESFKLWTGIYPDVE 251
ML+ Q A +F LW G+ PDVE
Sbjct: 239 GMLVAQAAHAFLLWHGVLPDVE 260
>pir||C75429 probable shikimate 5-dehydrogenase - Deinococcus radiodurans
(strain R1) >gi|6458910|gb|AAF10743.1|AE001966_5
(AE001966) shikimate 5-dehydrogenase, putative
[Deinococcus radiodurans]
Length = 330
Score = 139 bits (346), Expect = 4e-32
Identities = 98/257 (38%), Positives = 139/257 (53%), Gaps = 17/257 (6%)
Query: 6 LIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVE--ELGKAIDGVRALGISGLNVTMPYK 63
L P +HSLSP MH A F G++ Y V EL A+ +RA + G N+++P+K
Sbjct: 45 LFADPAAHSLSPRMHRAAFAWAGLNGTYDAERVPAPELPTAMARLRAPDVLGANLSLPHK 104
Query: 64 EVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGR-----NV 118
E LD LS+ AR I +VNT+I+ G L G TD G +AL + + GR V
Sbjct: 105 EAALPLLDGLSDAARAIGAVNTVIHRAGQLYGDNTDAPGLLQALAG-SGLTGRLGAADRV 163
Query: 119 LILGAGGAGKAIAYELSKI--ANIVVLNRTPSKAKSLEKFGVKGGSLDEL-PNYVGWADV 175
++LGAGGA +A Y + I + V+NRTP++A++L GG + P V W V
Sbjct: 164 VVLGAGGAARAAVYAGAVILGREVWVVNRTPARARALAAGWQGGGEVRAAGPGEVPWGQV 223
Query: 176 --LINATSVGM-GTNESLVPR---RLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGL 229
+IN++S G+ E+ +P L V D+VYKP +TRL+RDAE+ G +GL
Sbjct: 224 GLVINSSSAGLDNPEETPLPGFDFGQLPAHAGVYDMVYKPRRTRLMRDAEAAGLPAENGL 283
Query: 230 WMLIYQGAESFKLWTGI 246
ML Q +F WTG+
Sbjct: 284 GMLAQQARLAFTAWTGV 300
>pir||F82781 shikimate 5-dehydrogenase XF0624 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9105498|gb|AAF83434.1|AE003908_2
(AE003908) shikimate 5-dehydrogenase [Xylella
fastidiosa]
Length = 282
Score = 133 bits (332), Expect = 2e-30
Identities = 94/265 (35%), Positives = 140/265 (52%), Gaps = 21/265 (7%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVTMP 61
+ + G P++HSLSP +H R+ G+ Y+ F+V + +++ A G G NVT+P
Sbjct: 6 FAVFGHPIAHSLSPRIHTEFGRQMGVALNYLAFDVAPDAFRVSLERFVAEGGCGANVTLP 65
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVG-ARKALERF-TEIEGRNVL 119
KE + LS AR +VNT+ ++G G TDG G R ER ++ GR L
Sbjct: 66 LKEAAFEVCTTLSARARRAGAVNTLSRVDGVWHGENTDGTGLVRNLTERHGLDLRGRRAL 125
Query: 120 ILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSL-EKFGVKG-------GSLDELPNY 169
+LGAGGA + +A L + I +V++NR+P +A L + G G G L +L N+
Sbjct: 126 LLGAGGAARGVAPALLDAGITEMVIVNRSPERADMLCDALGEPGRVSARYWGDLGDLGNF 185
Query: 170 VGWADVLINATSVGMGTNESL--VPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR-VI 226
++++NATS+G ++ +PR LL +D+ Y L A +V R VI
Sbjct: 186 ----ELIVNATSIGNTSDMRTFSLPRSLLDSMTAAVDLNYGSAAVPFLAWAHAVETRYVI 241
Query: 227 DGLWMLIYQGAESFKLWTGIYPDVE 251
DGL ML+ Q AESF LW G PD +
Sbjct: 242 DGLGMLVEQAAESFSLWHGRRPDTD 266
>sp|P44774|YDIB_HAEIN HYPOTHETICAL PROTEIN HI0607 >gi|1075301|pir||H64080 hypothetical
protein HI0607 - Haemophilus influenzae (strain Rd KW20)
>gi|1573600|gb|AAC22266.1| (U32743) shikimate
5-dehydrogenase-related protein [Haemophilus influenzae
Rd]
Length = 271
Score = 132 bits (330), Expect = 3e-30
Identities = 85/255 (33%), Positives = 136/255 (53%), Gaps = 13/255 (5%)
Query: 6 LIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMPYKEV 65
L G+P + HN L+ K G++ +Y F +++ AI GVRALGI G V+MP+KE
Sbjct: 12 LSGRP--SNFGTTFHNYLYDKLGLNFIYKAFTTQDIEHAIKGVRALGIRGCAVSMPFKET 69
Query: 66 VTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNVLILGAGG 125
FLDE+ A+ I SVNTI+N G L Y TD + K +E++ + V++ G+GG
Sbjct: 70 CMPFLDEIHPSAQAIESVNTIVNDNGFLRAYNTDYIAIVKLIEKYHLNKNAKVIVHGSGG 129
Query: 126 AGKAI--AYELSKIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADVLINATSV 182
KA+ A++ S + + R + L +G ++ L N AD+L+N TS+
Sbjct: 130 MAKAVVAAFKNSGFEKLKIYARNVKTGQYLAALYGY--AYINSLENQ--QADILVNVTSI 185
Query: 183 GM-GTNESL---VPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQGAE 238
GM G E + P+ + + D+V P++T +R A++ G + I G +++ Q E
Sbjct: 186 GMKGGKEEMDLAFPKAFIDNASVAFDVVAMPVETPFIRYAQARGKQTISGAAVIVLQAVE 245
Query: 239 SFKLWTGIYPDVELM 253
F+L+T P EL+
Sbjct: 246 QFELYTHQRPSDELI 260
>sp|P95368|AROE_NEILA SHIKIMATE 5-DEHYDROGENASE >gi|1785898|gb|AAC44914.1| (U82843)
shikimate dehydrogenase [Neisseria lactamica]
Length = 269
Score = 132 bits (328), Expect = 5e-30
Identities = 88/256 (34%), Positives = 134/256 (51%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G++ Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHRQFALQEGVEIEYGRICADIGSFAQAVSTFFGTGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERF--TEIEGRNV 118
+K+ DE SE A +VNT+I LE G L G TDG+G + + TE+EG+N+
Sbjct: 67 FKQEAFDLADEHSERASAAGAVNTLILLENGKLRGDNTDGLGLVGDIVKVQNTEVEGKNI 126
Query: 119 LILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L A IV+ NRT +KA+ + +FG++ + +L G D+
Sbjct: 127 LLLGAGGAVRGVIPVLLAQNPARIVIANRTRAKAEEVAARFGIEAVPMADLN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR-VIDGLWMLIY 234
+IN TS G+ +P + + + D+VY L A G + DGL ML+
Sbjct: 184 IINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGEAAKPFLDFARQSGAKQTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYALWRGFKPDI 259
>sp|P95389|AROE_NEIMU SHIKIMATE 5-DEHYDROGENASE >gi|1785908|gb|AAC44919.1| (U82848)
shikimate dehydrogenase [Neisseria mucosa]
Length = 269
Score = 132 bits (328), Expect = 5e-30
Identities = 90/256 (35%), Positives = 132/256 (51%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G++ Y + + +A++ A G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHRQFALQEGVEIEYERICADTGGFAQAVEAFFADGGRGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERF--TEIEGRNV 118
+K+ DE SE A +VNT+I LE G + G TDG+G + + E+ G+ V
Sbjct: 67 FKQEAFALSDEHSERALAAGAVNTLILLENGKIRGDNTDGIGLTDDISKRLGVELSGKTV 126
Query: 119 LILGAGGAGKAIAYELSKI--ANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA + FG++ LDEL G D+
Sbjct: 127 LLLGAGGAVRGVIPVLKEYRPARIVIANRTHTKAAEMAAHFGIEAIPLDELE---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR-VIDGLWMLIY 234
+IN TS G+ V ++ + D+VY L A G + DGL ML+
Sbjct: 184 IINGTSGGLSGQLPAVSPKVFEHCTLAYDMVYGEAAEPFLAFARQSGAKQTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S++LW G PDV
Sbjct: 244 QAAASYRLWRGFAPDV 259
>gb|AAC44908.1| (U82837) shikimate dehydrogenase [Neisseria meningitidis]
Length = 269
Score = 131 bits (326), Expect = 9e-30
Identities = 88/256 (34%), Positives = 134/256 (51%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE SE A +VNT+I L+ G L G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFHLADEHSERALAAGAVNTLIFLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADV 175
L+LGAGG + + L + A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 127 LLLGAGGRVRGVIPVLKEHRPARIVIANRTHAKAEELARLFGIEAVPMADVN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDGLWMLIY 234
+IN TS G+ + V R + R + D+VY L A+S G V DGL ML+
Sbjct: 184 IINGTSGGLSGHCPAVSREIFRNCRLAYDMVYGDAAQAFLNFAQSNGAAEVSDGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ +W G PD+
Sbjct: 244 QAAASYHIWRGFTPDI 259
>gb|AAF71755.1|AF258797_1 (AF258797) shikimate dehydrogenase; AroE [Xanthomonas oryzae pv.
oryzae]
Length = 283
Score = 131 bits (325), Expect = 1e-29
Identities = 90/262 (34%), Positives = 134/262 (50%), Gaps = 15/262 (5%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HSLSP +H ++ GI Y + E+ A+ G G NVT+P
Sbjct: 6 YAVFGHPVAHSLSPAIHADFGKQTGIVLDYTAIDAPPEDFSAALQRFADGGGKGANVTLP 65
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKAL--ERFTEIEGRNVL 119
KE LS+ AR +VNT++ EG G TDG+G + L ++ GR VL
Sbjct: 66 LKEAACALASSLSDRARLAGAVNTLVRHEGQWQGENTDGIGLVRDLTDRHGLDLRGRRVL 125
Query: 120 ILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSL-----EKFGVKGGSLDELPNYVGW 172
+LGAGGA + +A L + I +VV+NR+P +A +L E V +++L + +G
Sbjct: 126 LLGAGGAARGVAPALLQAGITEMVVVNRSPERADALCDTLGEPGRVVSRYIEDLRD-LGD 184
Query: 173 ADVLINATSVGMGTNES--LVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR-VIDGL 229
++++NAT+ G + +P L+ +D+ Y L A S CR IDGL
Sbjct: 185 FELIVNATAAGRDRDAGAFAMPLGLVNSLTAAVDLNYGATAIAFLAWARSAQCRYAIDGL 244
Query: 230 WMLIYQGAESFKLWTGIYPDVE 251
ML+ AESF LW G+ PD +
Sbjct: 245 GMLVEHAAESFALWHGVRPDTD 266
>sp|P95399|AROE_NEIPO SHIKIMATE 5-DEHYDROGENASE >gi|1785900|gb|AAC44915.1| (U82844)
shikimate dehydrogenase [Neisseria polysaccharea]
Length = 269
Score = 130 bits (324), Expect = 2e-29
Identities = 88/256 (34%), Positives = 134/256 (51%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + +++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHQQFTLQEGVDIEYGRICADIDGFAQAVSTFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE S+ A +VNT+I L+ G L G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFALADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLVNDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + +L G D+
Sbjct: 127 LLLGAGGAVRGVIPVLKEHRPARIVIANRTHAKAEELARLFGIEAVPMADLN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDGLWMLIY 234
+IN TS G+ V + R + D+VY L A+S G V DGL ML+
Sbjct: 184 IINGTSGGLSGQLPAVNPEIFRSCRLAYDMVYGDAAQTFLNFAQSNGAAEVSDGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ +W G PD+
Sbjct: 244 QAAASYHIWRGFTPDI 259
>sp|P95337|AROE_NEICI SHIKIMATE 5-DEHYDROGENASE >gi|1785902|gb|AAC44916.1| (U82845)
shikimate dehydrogenase [Neisseria cinerea]
Length = 269
Score = 128 bits (318), Expect = 8e-29
Identities = 89/256 (34%), Positives = 131/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YTVFGNPVAHSKSPQIHQQFALQEGVDIEYGRICADIGGFAQAVSIFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE SE A +VNT+I LE G L G TDG+G + + I E + +
Sbjct: 67 FKQEAFALADEYSERASAAGAVNTLILLENGKLRGDNTDGIGLSNDITQVKNIAIECKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + +L G D+
Sbjct: 127 LLLGAGGAVRGVIPVLKEHRPARIVIANRTHAKAEELARLFGIEAVPMADLN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDGLWMLIY 234
+IN TS + V + R + D+VY L A+S G V DGL ML+
Sbjct: 184 IINGTSGSLSGQLPAVSPEIFRNCRLAYDMVYGDAAQAFLNFAQSNGAAEVSDGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYSLWRGFTPDI 259
>sp|P95340|AROE_NEIFL SHIKIMATE 5-DEHYDROGENASE >gi|1785906|gb|AAC44918.1| (U82847)
shikimate dehydrogenase [Neisseria flavescens]
Length = 269
Score = 128 bits (318), Expect = 8e-29
Identities = 88/256 (34%), Positives = 132/256 (51%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHRQFALQEGVDIEYERICADIGGFAQAVSTFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE SE A +VNT+I L+ G L G TDG+G + + I E + +
Sbjct: 67 FKQEAFDLADEHSERALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIEDKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + +L G D+
Sbjct: 127 LLLGAGGAVRGVIPVLKEHRPARIVITNRTHAKAEELARLFGIEAVPMADLN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDGLWMLIY 234
+IN TS G+ V + R + D+VY L A+S G V DGL ML+
Sbjct: 184 IINGTSGGLSGQLPAVSPEIFRDCRLAYDMVYGEAALAFLNFAQSNGAAEVSDGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ +W G PD+
Sbjct: 244 QAAASYHIWRGFTPDI 259
>sp|P95400|AROE_NEIPH SHIKIMATE 5-DEHYDROGENASE >gi|1785904|gb|AAC44917.1| (U82846)
shikimate dehydrogenase [Neisseria pharyngis var. flava]
Length = 269
Score = 127 bits (317), Expect = 1e-28
Identities = 89/256 (34%), Positives = 130/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G++ Y + ++ +A++ A G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHRQFALQEGVEIEYERICADIGGFAQAVEAFFANGGRGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALER--FTEIEGRNV 118
+K+ DE SE A +VNT+I LE G + G TDG+G + + EI + V
Sbjct: 67 FKQEAFALSDEHSERALAAGAVNTLILLENGKIRGDNTDGLGLTDDIAKRLGVEISDKTV 126
Query: 119 LILGAGGAGKAIAYELSKI--ANIVVLNRTPSKAKSLE-KFGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA + F + LDEL G D+
Sbjct: 127 LLLGAGGAVRGVIPVLKEYHPARIVIANRTHAKAAEMAVHFDIDAVPLDELE---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR-VIDGLWMLIY 234
+IN TS G+ V ++ + D+VY L A G + DGL ML+
Sbjct: 184 IINGTSGGLSGQLPAVSPKIFEHCTLAYDMVYGEAAEPFLAFARQSGAKQTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S++LW G PDV
Sbjct: 244 QAAASYRLWRGFAPDV 259
>sp|P56992|AROE_NEIMB SHIKIMATE 5-DEHYDROGENASE >gi|11251027|pir||E81208 shikimate
5-dehydrogenase NMB0358 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|1785892|gb|AAC44911.1| (U82840) shikimate
dehydrogenase [Neisseria meningitidis]
>gi|7225580|gb|AAF40801.1| (AE002392) shikimate
5-dehydrogenase [Neisseria meningitidis MC58]
Length = 269
Score = 126 bits (314), Expect = 2e-28
Identities = 86/256 (33%), Positives = 132/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE SE A +VNT+I L+ G L G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFHLADEHSERALAAGAVNTLIPLKNGKLRGDNTDGIGLTNDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 127 LLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADVN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDGLWMLIY 234
+IN TS G+ +P + + + D+VY L A G + DGL ML+
Sbjct: 184 IINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYALWRGFTPDI 259
>gb|AAC44913.1| (U82842) shikimate dehydrogenase [Neisseria gonorrhoeae]
Length = 269
Score = 126 bits (313), Expect = 3e-28
Identities = 84/256 (32%), Positives = 132/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G P +HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPAAHSKSPQIHQQFALQEGVDIEYGRICADIGGFAQAVSTFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE S+ A + +VNT++ LE G + G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFHLADEHSDRALAVGAVNTLVWLEDGRIRGDNTDGIGLANDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 127 LLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELARLFGIEAVPMADVN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDGLWMLIY 234
+IN TS G+ V ++ R + D+VY L A G + DGL ML+
Sbjct: 184 IINGTSGGLSGQLPAVSPKIFRDCRLAYDMVYGEAAKPFLDFARQSGAKKTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYALWRGFKPDI 259
>sp|P56991|AROE_NEIMA SHIKIMATE 5-DEHYDROGENASE >gi|11251025|pir||F81784 shikimate
dehydrogenase NMA2129 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380750|emb|CAB85341.1| (AL162758) shikimate
dehydrogenase [Neisseria meningitidis Z2491]
Length = 271
Score = 126 bits (313), Expect = 3e-28
Identities = 86/256 (33%), Positives = 132/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 9 YAVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFETGGCGANVTVP 68
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE SE A +VNT+I L+ G L G TDG+G + + I EG+ +
Sbjct: 69 FKQEAFHLADEHSERALAAGAVNTLIFLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTI 128
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 129 LLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADVN---GGFDI 185
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDGLWMLIY 234
+IN TS G+ +P + + + D+VY L A G + DGL ML+
Sbjct: 186 IINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGMLVG 245
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 246 QAAASYALWRGFTPDI 261
>sp|P95361|AROE_NEIGO SHIKIMATE 5-DEHYDROGENASE >gi|1778808|gb|AAC44900.1| (U82700)
shikimate dehydrogenase [Neisseria gonorrhoeae]
Length = 269
Score = 126 bits (313), Expect = 3e-28
Identities = 84/256 (32%), Positives = 132/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G P +HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPAAHSKSPQIHQQFALQEGVDIEYGRICADIGGFAQAVSTFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE S+ A +VNT++ LE G + G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFHLADEHSDRALAAGAVNTLVWLEDGRIRGDNTDGIGLANDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 127 LLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELARLFGIEAVPMADVN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDGLWMLIY 234
+IN TS G+ V ++ R + D+VY+ L A G + DGL ML+
Sbjct: 184 IINGTSGGLSGQLPAVSPKIFRDCRLAYDMVYREAAKPFLDFARQSGAKKTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYALWRGFKPDI 259
>sp|Q9WYI1|AROE_THEMA SHIKIMATE 5-DEHYDROGENASE >gi|7431141|pir||H72388 shikimate
5-dehydrogenase - Thermotoga maritima (strain MSB8)
>gi|4980847|gb|AAD35432.1|AE001715_8 (AE001715)
shikimate 5-dehydrogenase [Thermotoga maritima]
Length = 253
Score = 125 bits (312), Expect = 4e-28
Identities = 97/255 (38%), Positives = 142/255 (55%), Gaps = 16/255 (6%)
Query: 6 LIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALG-ISGLNVTMPYKE 64
+IG PV HS+SP ++N F++ G++ Y E+ + R L G N T+P+KE
Sbjct: 5 IIGYPVRHSISPRLYNEYFKRAGMNHSYGMEEIPPESFDTEIRRILEEYDGFNATIPHKE 64
Query: 65 VVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNVLILGAG 124
V +++ E SEDA+ I +VN + +G Y TD VG K+LE E V+++GAG
Sbjct: 65 RVMRYV-EPSEDAQRIKAVNCVFRGKG----YNTDWVGVVKSLEGVEVKEP--VVVVGAG 117
Query: 125 GAGKAIAYELSK--IANIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGWADVLINATSV 182
GA +A+ Y L + + +I V+NRT +AK+L+ F VK SLD+L V A L N TSV
Sbjct: 118 GAARAVIYALLQMGVKDIWVVNRTIERAKALD-FPVKIFSLDQLDEVVKKAKSLFNTTSV 176
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR-VIDGLWMLIYQGAESFK 241
GM E V L+ +V D++Y T L+ A +G + +I G M YQ E+ K
Sbjct: 177 GMKGEELPVSDDSLKNLSLVYDVIY--FDTPLVVKARKLGVKHIIKGNLMFYYQAMENLK 234
Query: 242 LWTGIYPDVELMRRV 256
+W GIY D E+ + V
Sbjct: 235 IW-GIY-DEEVFKEV 247
>gb|AAC44912.1| (U82841) shikimate dehydrogenase [Neisseria meningitidis]
Length = 269
Score = 125 bits (310), Expect = 7e-28
Identities = 84/256 (32%), Positives = 131/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHRQFALQEGVDIEYERICADIGGFAQAVSTFFGTGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE S+ A +VNT+I L+ G L G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFHLADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADV 175
L+LGAGG + + L + A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 127 LLLGAGGRVRGVIPVLKEHRPARIVIANRTRAKAEELSRLFGIEAVPMADVN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDGLWMLIY 234
+IN TS G+ +P + + + D+VY L A G + DGL ML+
Sbjct: 184 IINGTSGGLNGQIPDIPPDIFQNCALAYDMVYSCAAKPFLDFARQSGAKKTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYALWRGFTPDI 259
>gb|AAC44906.1| (U82835) shikimate dehydrogenase [Neisseria meningitidis]
Length = 269
Score = 124 bits (309), Expect = 9e-28
Identities = 85/256 (33%), Positives = 131/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFGTGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE S+ A +VNT+I L+ G L G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFHLADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADV 175
L+LGAGG + + L + A IV+ NRT +KA+ L + FG++ + +L G D+
Sbjct: 127 LLLGAGGRVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADLN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDGLWMLIY 234
+IN TS G+ +P + + + D+VY L A G + DGL ML+
Sbjct: 184 IINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYALWRGFTPDI 259
>gb|AAC44910.1| (U82839) shikimate dehydrogenase [Neisseria meningitidis]
Length = 269
Score = 124 bits (309), Expect = 9e-28
Identities = 86/256 (33%), Positives = 131/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFVQAVSTFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTE--IEGRNV 118
+K+ DE S+ A +VNT+I L+ G L G TDG+G + + I+G+N+
Sbjct: 67 FKQEAFALADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIDGKNI 126
Query: 119 LILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADV 175
L+LGAGG + + L A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 127 LLLGAGGRVRGVIPVLLAQNPARIVIANRTRAKAEELAQLFGIEAVPMADVN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDGLWMLIY 234
+IN TS G+ V + R + D+VY L A+S G V D L ML+
Sbjct: 184 VINGTSGGLNGQIPAVSPEIFRNCRLAYDMVYGDAAQEFLNFAQSNGAAEVSDALGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYALWRGFTPDI 259
>gb|AAC44907.1| (U82836) shikimate dehydrogenase [Neisseria meningitidis]
Length = 269
Score = 123 bits (307), Expect = 2e-27
Identities = 84/256 (32%), Positives = 131/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVAHSKSPQIHRQFALQEGVDIEYERICADIGGFAQAVSTFFGTGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE S+ A +VNT+I L+ G L G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFHLADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADV 175
L+LGAGG + + L + A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 127 LLLGAGGRVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADVN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDGLWMLIY 234
+IN TS G+ +P + + + D+VY L A G + DGL ML+
Sbjct: 184 IINGTSSGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYALWRGFTPDI 259
>gb|AAC44905.1| (U82834) shikimate dehydrogenase [Neisseria meningitidis]
Length = 269
Score = 123 bits (305), Expect = 3e-27
Identities = 85/256 (33%), Positives = 131/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+HS SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YSVFGNPVAHSKSPQIHRQFALQEGVDIEYGRICADIGGFAQAVSTFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE S+ A +VNT+I L+ G L G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFHLADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADV 175
L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 127 LLLGAGGAVRGVIPVLKEHRPARIVIANRTHAKAEELAQLFGIEAVPMADVN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR-VIDGLWMLIY 234
+IN TS G+ V + R + D+VY L A G + DGL ML+
Sbjct: 184 IINGTSGGLSGQLPAVNPEIFRDCRLAYDMVYGEAAKPFLDFARQSGAKQTADGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G P++
Sbjct: 244 QAAASYALWRGFTPNI 259
>sp|Q9Z6M4|ARDE_CHLPN SHIKIMATE BIOSYNTHESIS PROTEIN ARODE [INCLUDES: 3-DEHYDROQUINATE
DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE);
SHIKIMATE 5-DEHYDROGENASE ] >gi|7468553|pir||G72003
3-dehydroquinate dehydratase/shikimate 5-dehydrogenase
CP0817 [imported] - Chlamydophila pneumoniae (strains
CWL029 and AR39) >gi|4377368|gb|AAD19172.1| (AE001684)
Shikimate 5-Dehyrogenase [Chlamydophila pneumoniae
CWL029] >gi|7189731|gb|AAF38612.1| (AE002240)
3-dehydroquinate dehydratase/shikimate 5-dehydrogenase
[Chlamydophila pneumoniae AR39]
>gi|8979408|dbj|BAA99242.1| (AP002548) shikimate
5-dehyrogenase [Chlamydophila pneumoniae J138]
Length = 477
Score = 122 bits (304), Expect = 3e-27
Identities = 91/252 (36%), Positives = 127/252 (50%), Gaps = 17/252 (6%)
Query: 3 VYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVE--ELGKAIDGVRALGISGLNVTM 60
+YGLIG PV S+S + HN L K ++A Y+ F V E+ +R L SGL+VTM
Sbjct: 217 IYGLIGDPVDRSISHLSHNFLLSKLSLNATYIKFPVTIGEVVTFFSAIRDLPFSGLSVTM 276
Query: 61 PYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKAL-ERFTEIEGRNVL 119
P K + +D L A+ S+NT++ ++GY TDG G K L ++ + +++
Sbjct: 277 PLKTAIFDHVDALDASAQLCESINTLVFRNQKILGYNTDGEGVAKLLKQKNISVNNKHIA 336
Query: 120 ILGAGGAGKAIAYELS-KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADVLI 177
I+GAGGA KAIA L+ + AN+ + NRT S A +L K L L N+ D++I
Sbjct: 337 IVGAGGAAKAIAATLAMQGANLHIFNRTLSSAAALATCCKGKAYPLGSLENF-KTIDIII 395
Query: 178 NATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQGA 237
N E P R IVMDI KP + L A+ G +I G M I Q
Sbjct: 396 NCL-----PPEVTFPWRF---PPIVMDINTKPHPSPYLERAQKHGSLIIHGYEMFIEQAL 447
Query: 238 ESFKLWTGIYPD 249
F LW +PD
Sbjct: 448 LQFALW---FPD 456
>gb|AAC44909.1| (U82838) shikimate dehydrogenase [Neisseria meningitidis]
Length = 269
Score = 122 bits (303), Expect = 4e-27
Identities = 86/256 (33%), Positives = 130/256 (50%), Gaps = 12/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y + G PV+ S SP +H + G+D Y + ++ +A+ G G NVT+P
Sbjct: 7 YAVFGNPVATSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFETGGCGANVTVP 66
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEI--EGRNV 118
+K+ DE SE A +VNT+I L+ G L G TDG+G + + I EG+ +
Sbjct: 67 FKQEAFHLADEHSERALAAGAVNTLIFLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTI 126
Query: 119 LILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNYVGWADV 175
L+LGAGG + + L + A IV+ NRT +KA+ L + FG++ + ++ G D+
Sbjct: 127 LLLGAGGRVRGVIPVLKEHRPARIVIANRTHAKAEELARLFGIEAVPMADVN---GGFDI 183
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDGLWMLIY 234
+IN TS G+ V + + D+VY L A+S G V DGL ML+
Sbjct: 184 IINGTSGGLSGQLPAVSPEIFLGCRLAYDMVYGDAAQEFLNFAQSNGAAEVSDGLGMLVG 243
Query: 235 QGAESFKLWTGIYPDV 250
Q A S+ LW G PD+
Sbjct: 244 QAAASYALWRGFTPDI 259
>pir||C81384 shikimate 5-dehydrogenase (EC 1.1.1.25) Cj0405 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6967879|emb|CAB74241.1| (AL139075) shikimate
5-dehydrogenase [Campylobacter jejuni]
Length = 262
Score = 120 bits (299), Expect = 1e-26
Identities = 83/272 (30%), Positives = 131/272 (47%), Gaps = 24/272 (8%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTM 60
MK +IG P+SHS SP MHN + G+D++Y + + + LG+SG N+T+
Sbjct: 1 MKFLAVIGDPISHSKSPRMHNNAIKALGLDSIYTRYHLRNANCLREDFFKLGLSGANITL 60
Query: 61 PYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNVLI 120
P+KE D + AR I S NT+ E + Y TD +G +A++ F I + LI
Sbjct: 61 PFKEKALDIADVKDDFARNIGSANTLCLKEDKIYAYNTDALGFLEAIKDFDNI--KKALI 118
Query: 121 LGAGGAGKAIAYEL-SKIANIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGW------A 173
LGAGG A+AY L K + + NR+ + K + P Y+
Sbjct: 119 LGAGGTALALAYVLKQKGVEVYIANRSKERFKDFLAY----------PTYLYKNLQDFDF 168
Query: 174 DVLINATSVGMGTNESLVPRRLLRREL----IVMDIVYKPLKTRLLRDAESVGCRVIDGL 229
D++IN+TS G+ R LL R L +++Y +T R + ++ DGL
Sbjct: 169 DLVINSTSAGLKDENLPCDRELLDRILPKAKFAFEVIY-GRETPFYRLCKEYHLKIKDGL 227
Query: 230 WMLIYQGAESFKLWTGIYPDVELMRRVSLERL 261
ML++QG +F+L+ I E+++ + L
Sbjct: 228 DMLLWQGVFAFELFFEIQDKREMIKNAMQQAL 259
>pir||G82370 shikimate 5-dehydrogenase VC0056 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9654450|gb|AAF93234.1|
(AE004096) shikimate 5-dehydrogenase [Vibrio cholerae]
Length = 278
Score = 120 bits (299), Expect = 1e-26
Identities = 86/264 (32%), Positives = 134/264 (50%), Gaps = 15/264 (5%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVYVT--FEVEELGKAIDGVRALGISGLNVTMP 61
Y + G P++HS SP +H R+ +Y V+ +A A G G NVT+P
Sbjct: 8 YAVFGNPINHSKSPFIHTLFARQTQQSMIYTAQCVPVDGFTEAAKHFFAQGGRGCNVTVP 67
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINL-EGSLIGYTTDGVG-ARKALERFTEIEGRNVL 119
+KE +F D L+E AR +VNT+ L +G ++G TDG G + L + ++G +L
Sbjct: 68 FKEEAYRFADRLTERARLAGAVNTLKKLDDGEILGDNTDGEGLVQDLLAQQVLLKGATIL 127
Query: 120 ILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSLEKF-----GVKGGSLDELPNYVGW 172
++GAGGA + + L + A+I V NRT +KA+ L + VK + ++L
Sbjct: 128 LIGAGGAARGVLKPLLDQQPASITVTNRTFAKAEQLAELVAAYGEVKAQAFEQLKQSY-- 185
Query: 173 ADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDGLWM 231
DV+IN+TS + + + + D++Y T + A GC + IDGL M
Sbjct: 186 -DVIINSTSASLDGELPAIDPVIFSSRSVCYDMMYGKGYTVFNQWARQHGCAQAIDGLGM 244
Query: 232 LIYQGAESFKLWTGIYPDVELMRR 255
L+ Q AESF LW G+ P + + R
Sbjct: 245 LVGQAAESFMLWRGLRPGTKQILR 268
>pir||C75562 probable shikimate 5-dehydrogenase - Deinococcus radiodurans
(strain R1) >gi|6457742|gb|AAF09670.1|AE001871_2
(AE001871) shikimate 5-dehydrogenase, putative
[Deinococcus radiodurans]
Length = 273
Score = 119 bits (295), Expect = 4e-26
Identities = 86/247 (34%), Positives = 120/247 (47%), Gaps = 29/247 (11%)
Query: 20 HNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDARE 79
HN L+ G++ +Y F ++L AI G+RALGI G V+MP+KE V LDEL A
Sbjct: 29 HNYLYELLGLNYMYKAFTTQDLPAAIGGIRALGIRGCAVSMPFKEAVIPLLDELMPSAAA 88
Query: 80 INSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYEL--SKI 137
I SVNTI+N +G L Y TD R + V + G+GG GKA+A L +
Sbjct: 89 IESVNTIVNDDGVLRAYNTDYEAVRLLIREKELDPSWRVGVRGSGGMGKAVASALRDAGF 148
Query: 138 ANIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGW--------ADVLINATSVGM--GTN 187
N V++ R + + EL +GW AD+L+N T +GM G
Sbjct: 149 ENGVLVARNEAAGR-------------ELAGRLGWRWTPEPEAADLLVNVTPIGMAGGPE 195
Query: 188 E---SLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQGAESFKLWT 244
E S P L+ + V D+V P +T L+ +A G V+ G + Q E F L+T
Sbjct: 196 EHDLSFAP-ELIAQARAVFDVVALPAETPLIAEARRQGKPVVTGEEVAALQALEQFVLYT 254
Query: 245 GIYPDVE 251
G+ P E
Sbjct: 255 GVRPTPE 261
>sp|P43876|AROE_HAEIN SHIKIMATE 5-DEHYDROGENASE >gi|1075302|pir||H64084 shikimate
5-dehydrogenase homolog - Haemophilus influenzae
(strain Rd KW20) >gi|1573654|gb|AAC22314.1| (U32748)
shikimate 5-dehydrogenase (aroE) [Haemophilus influenzae
Rd]
Length = 272
Score = 115 bits (286), Expect = 4e-25
Identities = 87/261 (33%), Positives = 134/261 (51%), Gaps = 14/261 (5%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTF--EVEELGKAIDGVRALGISGLNV 58
M +Y + G P++ S SP++ N L + Y+ +++ + + G G N+
Sbjct: 1 MDLYAVWGNPIAQSKSPLIQNKLAAQTHQTMEYIAKLGDLDAFEQQLLAFFEEGAKGCNI 60
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GR 116
T P+KE + DE S+ A+ + NT+ L+ G L TDG+G L+R + +
Sbjct: 61 TSPFKERAYQLADEYSQRAKLAEACNTLKKLDDGKLYADNTDGIGLVTDLQRLNWLRPNQ 120
Query: 117 NVLILGAGGAGKAIAYELSKIA-NIVVLNRTPSKAKSL-EKF----GVKGGSLDELPNYV 170
+VLILGAGGA K + L + NIV+ NRT SK K L E+F ++ S+D +P +
Sbjct: 121 HVLILGAGGATKGVLLPLLQAQQNIVLANRTFSKTKELAERFQPYGNIQAVSMDSIP--L 178
Query: 171 GWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVY-KPLKTRLLRDAESVGC-RVIDG 228
D++INATS G+ + V +L+ D+ Y K T + +S+G V DG
Sbjct: 179 QTYDLVINATSAGLSGGTASVDAEILKLGSAFYDMQYAKGTDTPFIALCKSLGLTNVSDG 238
Query: 229 LWMLIYQGAESFKLWTGIYPD 249
ML+ Q A SF LW G+ PD
Sbjct: 239 FGMLVAQAAHSFHLWRGVMPD 259
>sp|Q9X5C9|AROE_CORGL SHIKIMATE 5-DEHYDROGENASE >gi|4838437|gb|AAD30993.1|AF124518_2
(AF124518) shikimate dehydrogenase [Corynebacterium
glutamicum]
Length = 280
Score = 114 bits (283), Expect = 1e-24
Identities = 78/262 (29%), Positives = 130/262 (48%), Gaps = 18/262 (6%)
Query: 5 GLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV-------EELGKAIDGVRALGISGLN 57
GLIG+ + S +P MH A G VY + ++L +D LG +GLN
Sbjct: 8 GLIGQGLDLSRTPAMHEAEGLPQGRATVYRRIDTLGSRASGQDLKTLLDAALYLGFNGLN 67
Query: 58 VTMPYKEVVTKFLDELSEDAREINSVNTI-INLEGSLIGYTTDGVGARKALERFTEIEGR 116
+T PYK+ V LDE+SE A ++ +VNT+ I+ G G+ TD G + +E
Sbjct: 68 ITHPYKQAVLPLLDEVSEQATQLGAVNTVVIDATGHTTGHNTDVSGFGRGMEEGLPNAKL 127
Query: 117 NVLILGAGGAGKAIAYELSK--IANIVVLNRTPSKAKSLE--------KFGVKGGSLDEL 166
+ ++ K Y L + + V + S+A++L + V G +
Sbjct: 128 DSVVQVGRRRRKRSRYALVTHGVQKLQVADLDTSRAQALADVINNAVGREAVVGVDARGI 187
Query: 167 PNYVGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVI 226
+ + AD ++NAT +GM + + L ++ V D+VY P++T LL+ A ++GC +
Sbjct: 188 EDVIAAADGVVNATPMGMPAHPTAFDVSCLTKDHWVGDVVYMPIETELLKAARALGCETL 247
Query: 227 DGLWMLIYQGAESFKLWTGIYP 248
DG M I+Q ++F+L+TG+ P
Sbjct: 248 DGTRMAIHQAVDAFRLFTGLEP 269
>emb|CAC11429.1| (AL445063) shikimate 5-dehydrogenase related protein [Thermoplasma
acidophilum]
Length = 268
Score = 114 bits (283), Expect = 1e-24
Identities = 90/267 (33%), Positives = 132/267 (48%), Gaps = 14/267 (5%)
Query: 3 VYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMPY 62
+ GLIG PVSHS+ +++N +F+ GIDA Y+ +V + + NVT+P+
Sbjct: 6 IIGLIGHPVSHSIGQILYNRIFQDMGIDAFYLAMDVHMNVLPAFLKNSFFLKAFNVTIPH 65
Query: 63 KEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALE-RFTEIEGRNVLIL 121
K + FLD+L E A + SVN +I + + GY TD G AL EIE + ++I
Sbjct: 66 KVSIIPFLDDLDEIASQTRSVNLVIREQSRMKGYNTDYYGLDYALSFNQVEIEEKRIVIA 125
Query: 122 GAGG-AGKAIAYELSKIANIV-VLNRTPSKAKSLEKFGVKGGSLDELPNYVGWADVLINA 179
G+GG A I Y L A+ V VL R A+ + G L E N D+ +N
Sbjct: 126 GSGGIARTVIRYMLDHGAHRVDVLTRNAQNAR--RNLDIPGIGLHE--NIDEDYDIYVNC 181
Query: 180 T---SVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQG 236
T ++G G S V R R + D+VY P T L+ + G R + GL + I QG
Sbjct: 182 TPLGTLGDGDPFSTVDFRSGRTGI---DLVYNPPDTPFLKRMRNAGGRTVSGLDVFIGQG 238
Query: 237 AESFKLWTGIYPDVELMRRVSLERLGK 263
+ +L GI PD + R ++E L +
Sbjct: 239 LRTLELVFGIRPD-SIFREYAVEALNE 264
>sp|Q9YEK4|Y574_AERPE PUTATIVE SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN APE0574
>gi|7521412|pir||F72642 probable shikimate dehydrogenase
APE0574 - Aeropyrum pernix (strain K1)
>gi|5104227|dbj|BAA79542.1| (AP000060) 225aa long
hypothetical shikimate dehydrogenase [Aeropyrum pernix]
Length = 225
Score = 113 bits (279), Expect = 3e-24
Identities = 72/220 (32%), Positives = 111/220 (49%), Gaps = 9/220 (4%)
Query: 53 ISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTE 112
+ G NVT P K L AR I +VNT++ E G+ TD G +L+ +T
Sbjct: 5 LHGFNVTKPLKREALSLASTLDSHARAIGAVNTMVAGEEGWEGFNTDWKGFLDSLKLYTA 64
Query: 113 IEGRNVLILGAGGAGKAIAYELSK--IANIVVLNRTPSKAK-SLEKFGVKGGSLDELP-- 167
L++GAGGAG+A AY L+ +++ +RT A+ + + G ++ +P
Sbjct: 65 SPPDTALVIGAGGAGRAAAYALATWGAGRVLIASRTGLTARRAAQDLAGLGAEVEPVPPG 124
Query: 168 ---NYVGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR 224
+ +DV++NAT +G + V R R I +D+VY+PL T LR A + GC
Sbjct: 125 GLEDAAAASDVVVNATPLGWDGVSTPVERGF-REGCIAVDMVYRPLATPFLRRAAASGCT 183
Query: 225 VIDGLWMLIYQGAESFKLWTGIYPDVELMRRVSLERLGKG 264
+DGLWML Q AE+ +W G+ +R +LE + G
Sbjct: 184 PVDGLWMLAIQAAENIAVWLGLEASPVELRTYALEAMRGG 223
>pir||T50113 pentafunctional enzyme arom [imported] - fission yeast
(Schizosaccharomyces pombe) >gi|7019762|emb|CAB75770.1|
(AL157734) pentafunctional arom polypeptide [includes
3-dehydroquinate synthase](ec 4.6.1.3); 3-dehydroquinate
dehydratase [Schizosaccharomyces pombe]
Length = 1573
Score = 112 bits (278), Expect = 4e-24
Identities = 78/263 (29%), Positives = 126/263 (47%), Gaps = 22/263 (8%)
Query: 6 LIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMPYKEV 65
L GKP+ HS SP++H+ + G+ Y FE + + + + G NVT+PYK
Sbjct: 1298 LFGKPIKHSRSPILHSTAYELLGLPHTYEAFETDTVDEVQKVLNLPDFGGANVTIPYKLS 1357
Query: 66 VTKFLDELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERF------TEIEGRNV 118
V KF+DELS++AR +VNTII + G + D R + F + N
Sbjct: 1358 VMKFMDELSDEARFFGAVNTIIPIRIGDKLVLRGDNTDWRGIYDTFANALDGVSLRDTNG 1417
Query: 119 LILGAGGAGKAIAYELSK--IANIVVLNRTPSKAKSLEKFGVKGGSL----------DEL 166
L++GAGG +A Y L + ++ I +LNRT + + ++ ++ +EL
Sbjct: 1418 LVIGAGGTSRAAIYSLHRLGVSRIYLLNRTLANSYRVQDVFPPDYNIHIIDSDNIPSEEL 1477
Query: 167 PNYVGWADVLINATSVGMGTNESLVPRRLLRREL---IVMDIVYKPLKTRLLRDAESVGC 223
+ A V + + + V + LL + + +D+ YKPL T L+ A +
Sbjct: 1478 SSVTLSAVVSTIPADIELPEKVASVIKALLANKADGGVFLDMAYKPLHTPLMAVASDLEW 1537
Query: 224 RVIDGLWMLIYQGAESFKLWTGI 246
+ +GL L+ QG SF LWTG+
Sbjct: 1538 KCCNGLEALVRQGLASFHLWTGM 1560
>pir||G83641 shikimate dehydrogenase PA0025 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9945845|gb|AAG03415.1|AE004442_2
(AE004442) shikimate dehydrogenase [Pseudomonas
aeruginosa]
Length = 274
Score = 107 bits (264), Expect = 2e-22
Identities = 89/262 (33%), Positives = 128/262 (47%), Gaps = 18/262 (6%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISG--LNV 58
M Y + G P+ HS SP++H LF + +A+ ++ L R G NV
Sbjct: 1 MDRYCVFGNPIGHSKSPLIHR-LFAEQTGEALVYDAQLAPLDDFPGFARRFFEQGKGANV 59
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIINL-EGSLIGYTTDGVGARKAL--ERFTEIEG 115
T+P+KE + +DELSE A +VNT+I L +G L G TDG G + L E+ G
Sbjct: 60 TVPFKEEAYRLVDELSERATRAGAVNTLIRLADGRLRGDNTDGAGLLRDLTANAGVELRG 119
Query: 116 RNVLILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSL-EKF----GVKGGSLDELPN 168
+ VL+LGAGGA + + A +++ NRT KA L E+F V G E+
Sbjct: 120 KRVLLLGAGGAVRGVLEPFLGECPAELLIANRTARKAVDLAERFADLGAVHGCGFAEVE- 178
Query: 169 YVGWADVLINATSVGM-GTNESLVPRRLLRRELIVMDIVYKPLKTRLLR-DAESVGCRVI 226
G D+++N TS + G L + + D++Y T R AE R +
Sbjct: 179 --GPFDLIVNGTSASLAGDVPPLAQSVIEPGRTVCYDMMYAKEPTAFNRWAAERGAARTL 236
Query: 227 DGLWMLIYQGAESFKLWTGIYP 248
DGL ML+ Q AE+F LW G+ P
Sbjct: 237 DGLGMLVEQAAEAFFLWRGVRP 258
>sp|P43904|AROE_PSEAE SHIKIMATE 5-DEHYDROGENASE >gi|747873|emb|CAA59377.1| (X85015)
shikimate 5-dehydrogenase [Pseudomonas aeruginosa]
Length = 274
Score = 106 bits (262), Expect = 3e-22
Identities = 88/262 (33%), Positives = 128/262 (48%), Gaps = 18/262 (6%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISG--LNV 58
M Y + G P+ HS SP++H LF + +A+ ++ L R G NV
Sbjct: 1 MDRYCVFGNPIGHSKSPLIHR-LFAEQTGEALVYDAQLAPLDDFPGFARRFFEQGKGANV 59
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIINL-EGSLIGYTTDGVGARKAL--ERFTEIEG 115
T+P+KE + +DELSE A +VNT+I L +G L G TDG G + L ++ G
Sbjct: 60 TVPFKEEAYRLVDELSERATRAGAVNTLIRLADGRLRGDNTDGAGLLRDLTANAGVDVRG 119
Query: 116 RNVLILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSL-EKF----GVKGGSLDELPN 168
+ VL+LGAGGA + + A +++ NRT KA L E+F V G E+
Sbjct: 120 KRVLLLGAGGAVRGVLEPFLGECPAELLIANRTARKAVDLAERFADLGAVHGCGFAEVE- 178
Query: 169 YVGWADVLINATSVGM-GTNESLVPRRLLRRELIVMDIVYKPLKTRLLR-DAESVGCRVI 226
G D+++N TS + G L + + D++Y T R AE R +
Sbjct: 179 --GPFDLIVNGTSASLAGDVPPLAQSVIEPGRTVCYDMMYAKEPTAFNRWAAERGAARTL 236
Query: 227 DGLWMLIYQGAESFKLWTGIYP 248
DGL ML+ Q AE+F LW G+ P
Sbjct: 237 DGLGMLVEQAAEAFFLWRGVRP 258
>pir||S52925 shikimate 5-dehydrogenase (EC 1.1.1.25) - Pseudomonas aeruginosa
Length = 280
Score = 106 bits (262), Expect = 3e-22
Identities = 88/262 (33%), Positives = 128/262 (48%), Gaps = 18/262 (6%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISG--LNV 58
M Y + G P+ HS SP++H LF + +A+ ++ L R G NV
Sbjct: 1 MDRYCVFGNPIGHSKSPLIHR-LFAEQTGEALVYDAQLAPLDDFPGFARRFFEQGKGANV 59
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIINL-EGSLIGYTTDGVGARKAL--ERFTEIEG 115
T+P+KE + +DELSE A +VNT+I L +G L G TDG G + L ++ G
Sbjct: 60 TVPFKEEAYRLVDELSERATRAGAVNTLIRLADGRLRGDNTDGAGLLRDLTANAGVDVRG 119
Query: 116 RNVLILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSL-EKF----GVKGGSLDELPN 168
+ VL+LGAGGA + + A +++ NRT KA L E+F V G E+
Sbjct: 120 KRVLLLGAGGAVRGVLEPFLGECPAELLIANRTARKAVDLAERFADLGAVHGCGFAEVE- 178
Query: 169 YVGWADVLINATSVGM-GTNESLVPRRLLRRELIVMDIVYKPLKTRLLR-DAESVGCRVI 226
G D+++N TS + G L + + D++Y T R AE R +
Sbjct: 179 --GPFDLIVNGTSASLAGDVPPLAQSVIEPGRTVCYDMMYAKEPTAFNRWAAERGAARTL 236
Query: 227 DGLWMLIYQGAESFKLWTGIYP 248
DGL ML+ Q AE+F LW G+ P
Sbjct: 237 DGLGMLVEQAAEAFFLWRGVRP 258
>sp|Q9ZJX8|AROE_HELPJ SHIKIMATE 5-DEHYDROGENASE >gi|7431143|pir||A71841 shikimate
5-dehydrogenase - Helicobacter pylori (strain J99)
>gi|4155767|gb|AAD06744.1| (AE001544) SHIKIMATE
5-DEHYDROGENASE [Helicobacter pylori J99]
Length = 266
Score = 106 bits (261), Expect = 4e-22
Identities = 83/249 (33%), Positives = 125/249 (49%), Gaps = 13/249 (5%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALF----RKYGIDAVYVTFEVEELGKAIDGVRALGISGL 56
+K +G+ G P+ HS SP++HNA F ++ G Y + + + LG+SG
Sbjct: 3 LKSFGVFGNPIKHSKSPLIHNACFLTFQKELGFLGHYHPILLPLESRIKNEFLHLGLSGA 62
Query: 57 NVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGR 116
NVT+P+KE + D++ A E SVNT++ L+GY TD +G +L+ +
Sbjct: 63 NVTLPFKERAFQICDKIKGIALECASVNTLVLENDELVGYNTDALGFYLSLKHQNYQNDQ 122
Query: 117 NVLILGAGGAGKAIAYELSKIA-NIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGWADV 175
N LILGAGG+ KA+A L K + VLNR+ A+ L+ F G P + D+
Sbjct: 123 NALILGAGGSAKALACGLQKQGLKVSVLNRS---ARGLDFFQRLGCDCFMEPPKSAF-DL 178
Query: 176 LINATSVGMGTNESL---VPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWML 232
+INATS + L V + + + D+ Y L T L A+ + DG ML
Sbjct: 179 IINATSASLHNELPLNKEVLKGYFKESKLAYDLAYGFL-TPFLSLAKELKIPFQDGKDML 237
Query: 233 IYQGAESFK 241
IYQ + SF+
Sbjct: 238 IYQASLSFE 246
>gi|6320332 pentafunctional arom polypeptide (contains: 3-dehydroquinate
synthase, 3-dehydroquinate dehydratase
(3-dehydroquinase), shikimate 5-dehydrogenase, shikimate
kinase, and epsp synthase); Aro1p [Saccharomyces
cerevisiae] >gi|114166|sp|P08566|ARO1_YEAST
PENTAFUNCTIONAL AROM POLYPEPTIDE [INCLUDES:
3-DEHYDROQUINATE SYNTHASE ; 3-DEHYDROQUINATE DEHYDRATASE
(3-DEHYDROQUINASE); SHIKIMATE 5-DEHYDROGENASE ; SHIKIMATE
KINASE ; 3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE
(5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYN>
>gi|66631|pir||BVBYA1 ARO1 protein - yeast (Saccharomyces
cerevisiae) >gi|3381|emb|CAA29458.1| (X06077) arom
multifunctional enzyme (AA 1-1588) [Saccharomyces
cerevisiae] >gi|665659|emb|CAA88208.1| (Z48179) Aro1p
[Saccharomyces cerevisiae]
Length = 1588
Score = 104 bits (257), Expect = 1e-21
Identities = 82/270 (30%), Positives = 132/270 (48%), Gaps = 37/270 (13%)
Query: 6 LIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEEL----GKAIDGVRALGISGLNVTMP 61
++GKP+ HS SP++HN + G+ + FE E K +DG + G G VT+P
Sbjct: 1311 VVGKPIGHSRSPILHNTGYEILGLPHKFDKFETESAQLVKEKLLDGNKNFG--GAAVTIP 1368
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLEGSLI-GYTTDGVGARKAL--ERFTEIEGRNV 118
K + +++DEL++ A+ I +VNT+I L G TD +G R AL E G
Sbjct: 1369 LKLDIMQYMDELTDAAKVIGAVNTVIPLGNKKFKGDNTDWLGIRNALINNGVPEYVGHTA 1428
Query: 119 -LILGAGGAGKAIAYELSKIA--NIVVLNRTPSKAKSL-----EKFGVKG----GSLDEL 166
L++GAGG +A Y L + I ++NRT SK K L +F + G S++E+
Sbjct: 1429 GLVIGAGGTSRAALYALHSLGCKKIFIINRTTSKLKPLIESLPSEFNIIGIESTKSIEEI 1488
Query: 167 PNYVGWADVLINATSVGMGTNESLVPRRLLRRELI----------VMDIVYKPLKTRLLR 216
+VG V ++ ++ L+ + L R L+ +++ YKP T ++
Sbjct: 1489 KEHVG---VAVSCVPADKPLDDELLSK--LERFLVKGAHAAFVPTLLEAAYKPSVTPVMT 1543
Query: 217 -DAESVGCRVIDGLWMLIYQGAESFKLWTG 245
+ V+ G ML++QG F+ WTG
Sbjct: 1544 ISQDKYQWHVVPGSQMLVHQGVAQFEKWTG 1573
>sp|P46240|AROE_BUCAP SHIKIMATE 5-DEHYDROGENASE >gi|780130|gb|AAD09433.1| (U09230)
shikimate dehydrogenase [Buchnera aphidicola]
Length = 272
Score = 102 bits (253), Expect = 3e-21
Identities = 79/256 (30%), Positives = 122/256 (46%), Gaps = 11/256 (4%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMP 61
Y L G P+ HS SP +HN + GI +Y + +++ + I G NVT P
Sbjct: 9 YALFGNPIDHSQSPKIHNFFATQTGILHIYKAINIPLDQFSSVVSDFFKKNIKGANVTAP 68
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINL-EGSLIGYTTDGVGARKALERFTEIEGR-NVL 119
+K+ F D+L+E A+ SVNT+ + + ++G TDG+G L R I+ ++L
Sbjct: 69 FKKEAYFFSDKLTERAKIAQSVNTLKKISDKCILGDNTDGIGLLSDLVRLNFIKKNFSIL 128
Query: 120 ILGAGGAGKAIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL---DELPNYVGWADV 175
ILGAGGA K + L + ++ +LNRT AK L K K G + D D+
Sbjct: 129 ILGAGGAVKGVLLPLLSLGCSVYILNRTILNAKILVKQFNKYGKIFVFDRQNFKQQNFDL 188
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVI-DGLWMLIY 234
+INA S T + L+ + D+ Y T + G I +G+ ML++
Sbjct: 189 VINAMS--RNTEKKNFTLILITSKRFFYDMNYSTRNTPFINWCSKAGGSFISNGIGMLVF 246
Query: 235 QGAESFKLWTGIYPDV 250
Q A SF W + P++
Sbjct: 247 QAAYSFLEWHNVLPEI 262
>sp|P56119|AROE_HELPY SHIKIMATE 5-DEHYDROGENASE >gi|7431142|pir||A64676 shikimate
5-dehydrogenase - Helicobacter pylori (strain 26695)
>gi|2314414|gb|AAD08294.1| (AE000630) shikimate
5-dehydrogenase (aroE) [Helicobacter pylori 26695]
Length = 263
Score = 102 bits (252), Expect = 4e-21
Identities = 81/249 (32%), Positives = 125/249 (49%), Gaps = 16/249 (6%)
Query: 1 MKVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRA----LGISGL 56
+K +G+ G P+ HS SP++HNA F + + ++ L +++ LG+SG
Sbjct: 3 LKSFGVFGNPIKHSKSPLIHNACFLTFQKELRFLGHYHPILLPLESHIKSEFLHLGLSGA 62
Query: 57 NVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGR 116
NVT+P+KE + D++ A E +VNT++ L+GY TD +G +L+ + +
Sbjct: 63 NVTLPFKERAFQVCDKIKGIALECGAVNTLVLENDELVGYNTDALGFYLSLK---QKNYQ 119
Query: 117 NVLILGAGGAGKAIAYELSKIA-NIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGWADV 175
N LILGAGG+ KA+A EL K + VLNR+ ++ G E P D+
Sbjct: 120 NALILGAGGSAKALACELKKQGLQVSVLNRSSRGLDFFQRLGC--DCFMEPPKSA--FDL 175
Query: 176 LINATSVGMGTNESL---VPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWML 232
+INATS + L V + + + D+ Y L T L A+ + DG ML
Sbjct: 176 IINATSASLHNELPLNKEVLKGYFKEGKLAYDLAYGFL-TPFLSLAKELKTPFQDGKDML 234
Query: 233 IYQGAESFK 241
IYQ A SF+
Sbjct: 235 IYQAALSFE 243
>sp|Q44607|AROE_BUCAI SHIKIMATE 5-DEHYDROGENASE >gi|10039152|dbj|BAB13186.1| (AP001119)
shikimate 5-dehydrogenase [Buchnera sp. APS]
Length = 273
Score = 101 bits (250), Expect = 7e-21
Identities = 72/257 (28%), Positives = 128/257 (49%), Gaps = 9/257 (3%)
Query: 4 YGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVTMP 61
Y + G P++HS SP +H+ ++ GI Y + V L + G N+T P
Sbjct: 9 YAVFGNPINHSKSPEIHSLFSKQTGISHFYKSCNVPLNSLYAVLQDFFKKDGRGANITAP 68
Query: 62 YKEVVTKFLDELSEDAREINSVNTIINLEG-SLIGYTTDGVGARKALERFTEIEGR-NVL 119
+K+ F ++L++ A SVNT+ ++ +++G TDG+G L R I+ ++L
Sbjct: 69 FKQEAYFFCNKLTKRAEVAQSVNTLKKIDNCNILGDNTDGIGLLSDLIRLNFIKKNYSIL 128
Query: 120 ILGAGGAGKAIAYEL-SKIANIVVLNRTPSKAKSLEKFGVKGGSLDELPN---YVGWADV 175
I+GAGGA + + + L S +I + NRT A+ L K G+++ +V D+
Sbjct: 129 IIGAGGAARGVLFPLLSYGCSICIFNRTVLNAEKLVLQFHKYGNINVFNTNSLHVKSFDL 188
Query: 176 LINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVI-DGLWMLIY 234
+INATS + ++ +P + + D+ Y+ T + G +G+ ML++
Sbjct: 189 IINATSHFIQDKDNFIPFSCVSSKTCFYDMNYQTDNTFFFDWSRKTGSNFFSNGIGMLVF 248
Query: 235 QGAESFKLWTGIYPDVE 251
Q A SF LW + P+++
Sbjct: 249 QAAHSFFLWHNVLPEID 265
>sp|Q12659|ARO1_PNECA PENTAFUNCTIONAL AROM POLYPEPTIDE [INCLUDES: 3-DEHYDROQUINATE SYNTHASE
; 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE);
SHIKIMATE 5-DEHYDROGENASE ; SHIKIMATE KINASE ;
3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE
(5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYN>
>gi|7489936|pir||T30832 pentafunctional enzyme -
Pneumocystis carinii >gi|475972|gb|AAA17839.1| (L18918)
pentafunctional enzyme [Pneumocystis carinii]
Length = 1581
Score = 101 bits (249), Expect = 1e-20
Identities = 88/272 (32%), Positives = 130/272 (47%), Gaps = 30/272 (11%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMP 61
K Y L GKP+ HS SP +HN F G+ Y FE + + + + + G +VT+P
Sbjct: 1299 KKYFLFGKPIKHSQSPNIHNLGFEILGLPYKYQLFETDSISELKEILHLEEFGGASVTIP 1358
Query: 62 YKEVVTKFLDELSEDAREINSVNTII----NLEGSLIGYTTDGVGARKALERFTE----I 113
K ++ LDE+S+ A I SVNTI N + L G TD G KA++ F +
Sbjct: 1359 LKTNISILLDEISDHAALIGSVNTITRTYNNGQYILKGENTDWQGIIKAIKNFNKFEKSF 1418
Query: 114 EGRNVLILGAGGAGKAIAYELSK--IANIVVLNRTPSKAKSLEKFG-----VKGGSLDEL 166
E + I+GAGGA +A Y L I+ I ++NR+ K L F + EL
Sbjct: 1419 ENFSGFIIGAGGASRAAIYALLSLGISPIYLINRSKDKLNKLYHFFNTNHIIPITEYHEL 1478
Query: 167 PNYVGWADVLINATSVGMGTNESLVPRRL--------LRR---ELIVMDIVYKPLKTRLL 215
N D+ I +++ T+ + P L L+R E I +D+ Y T L
Sbjct: 1479 NNIN--FDIRIGISTI--PTDNPIDPSVLEIAKIFFNLKRKSSEGIFLDMAYGSNTTDLT 1534
Query: 216 RDAESVGCRVIDGLWMLIYQGAESFKLWTGIY 247
A++ ++I GL +L+ QG+E F LWT Y
Sbjct: 1535 IIAKACNWKIIHGLEILLEQGSEQFLLWTETY 1566
>sp|P56961|ARDE_CHLMU SHIKIMATE BIOSYNTHESIS PROTEIN ARODE [INCLUDES: 3-DEHYDROQUINATE
DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE);
SHIKIMATE 5-DEHYDROGENASE ] >gi|11360416|pir||G81679
3-dehydroquinate dehydratase/shikimate 5-dehydrogenase
TC0649 [imported] - Chlamydia muridarum (strain Nigg)
>gi|7190686|gb|AAF39475.1| (AE002332) 3-dehydroquinate
dehydratase/shikimate 5-dehydrogenase [Chlamydia
muridarum]
Length = 478
Score = 100 bits (246), Expect = 2e-20
Identities = 71/247 (28%), Positives = 118/247 (47%), Gaps = 16/247 (6%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVT 59
++ LIG S S+ + HN F + I YV + +EL + +RAL G++VT
Sbjct: 215 QICALIGD-TSRSIGHLTHNPFFSQLSIPCPYVKLPLTPQELPEFFSSIRALPFLGISVT 273
Query: 60 MPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFT-EIEGRNV 118
P K + FLD+ + S NT++ +G +IGY TDG G L + ++ + V
Sbjct: 274 SPLKTAIIPFLDKQDSSVKLSGSCNTLVIRQGEIIGYDTDGEGLFSVLTQHNMDLSNQRV 333
Query: 119 LILGAGGAGKAIAYELSKI-ANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADVL 176
ILGAGGA ++IA LS+ +++ NRT A+++ ++ + + +LP + ++
Sbjct: 334 AILGAGGAARSIAARLSRTGCELLIFNRTKIHAEAIASRYQAQAFDIKDLPLHS--VSLI 391
Query: 177 INATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQG 236
IN ++L P +++DI P + A GC +I G M Q
Sbjct: 392 INCLPPSSIIPQALAP--------LIVDINTLPKHNSFTQYARLKGCSIIYGHEMFAQQA 443
Query: 237 AESFKLW 243
F+LW
Sbjct: 444 LLQFRLW 450
>emb|CAA13278.1| (AJ232275) shikimate dehydrogenase [Streptococcus pneumoniae]
>gi|3821435|emb|CAA13285.1| (AJ232282) shikimate
dehydrogenase [Streptococcus pneumoniae]
>gi|3821447|emb|CAA13291.1| (AJ232288) shikimate
dehydrogenase [Streptococcus pneumoniae]
>gi|3821457|emb|CAA13296.1| (AJ232293) shikimate
dehydrogenase [Streptococcus pneumoniae]
>gi|6723933|emb|CAB67246.1| (AJ271344) shikimate
dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 96.7 bits (237), Expect = 2e-19
Identities = 52/118 (44%), Positives = 76/118 (64%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LDELS++AR I +VNT++N G+LIGY
Sbjct: 1 EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAA13282.1| (AJ232279) shikimate dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 96.7 bits (237), Expect = 2e-19
Identities = 52/118 (44%), Positives = 76/118 (64%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LDELS++AR I +VNT++N G+LIGY
Sbjct: 1 EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAB60631.1| (AJ252518) shikimate dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 96.0 bits (235), Expect = 4e-19
Identities = 52/118 (44%), Positives = 75/118 (63%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LDELS +AR I +VNT++N G+LIGY
Sbjct: 1 EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSNEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAA13283.1| (AJ232280) shikimate dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 95.6 bits (234), Expect = 6e-19
Identities = 51/118 (43%), Positives = 76/118 (64%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LD+LS++AR I +VNT++N G+LIGY
Sbjct: 1 EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMGKT 117
>emb|CAA13289.1| (AJ232286) shikimate dehydrogenase [Streptococcus pneumoniae]
>gi|3821445|emb|CAA13290.1| (AJ232287) shikimate
dehydrogenase [Streptococcus pneumoniae]
>gi|3821453|emb|CAA13294.1| (AJ232291) shikimate
dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 95.6 bits (234), Expect = 6e-19
Identities = 52/118 (44%), Positives = 76/118 (64%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LDELS++AR I +VNT++N G+LIGY
Sbjct: 1 EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAB60632.1| (AJ252519) shikimate dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 95.2 bits (233), Expect = 7e-19
Identities = 51/118 (43%), Positives = 76/118 (64%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LD+LS++AR I +VNT++N G+LIGY
Sbjct: 1 EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAA13279.1| (AJ232276) shikimate dehydrogenase [Streptococcus pneumoniae]
>gi|3821441|emb|CAA13288.1| (AJ232285) shikimate
dehydrogenase [Streptococcus pneumoniae]
>gi|3821449|emb|CAA13292.1| (AJ232289) shikimate
dehydrogenase [Streptococcus pneumoniae]
>gi|6434075|emb|CAB60634.1| (AJ252521) shikimate
dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 95.2 bits (233), Expect = 7e-19
Identities = 51/118 (43%), Positives = 76/118 (64%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LD+LS++AR I +VNT++N G+LIGY
Sbjct: 1 EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAA13281.1| (AJ232278) shikimate dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 95.2 bits (233), Expect = 7e-19
Identities = 51/118 (43%), Positives = 76/118 (64%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LD+LS++AR I +VNT++N G+LIGY
Sbjct: 1 EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAA13286.1| (AJ232283) shikimate dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 95.2 bits (233), Expect = 7e-19
Identities = 51/118 (43%), Positives = 75/118 (63%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LDELS++ R I +VNT++N G+LIGY
Sbjct: 1 EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEVRLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAA13293.1| (AJ232290) shikimate dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 95.2 bits (233), Expect = 7e-19
Identities = 51/118 (43%), Positives = 77/118 (65%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LD+LS++AR I +VNT++N G+LIGY
Sbjct: 1 EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ +++LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMILLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAA13284.1| (AJ232281) shikimate dehydrogenase [Streptococcus pneumoniae]
>gi|3821439|emb|CAA13287.1| (AJ232284) shikimate
dehydrogenase [Streptococcus pneumoniae]
>gi|6434073|emb|CAB60633.1| (AJ252520) shikimate
dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 94.0 bits (230), Expect = 2e-18
Identities = 51/118 (43%), Positives = 76/118 (64%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LD+LS++AR I +VNT++N G+LIGY
Sbjct: 1 EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>sp|O84375|ARDE_CHLTR SHIKIMATE BIOSYNTHESIS PROTEIN ARODE [INCLUDES: 3-DEHYDROQUINATE
DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE);
SHIKIMATE 5-DEHYDROGENASE ] >gi|7469046|pir||C71523
probable shikimate 5-dehyrogenase - Chlamydia
trachomatis (serotype D, strain UW3/Cx)
>gi|3328794|gb|AAC67966.1| (AE001310) Shikimate
5-Dehyrogenase [Chlamydia trachomatis]
Length = 478
Score = 93.6 bits (229), Expect = 2e-18
Identities = 72/246 (29%), Positives = 116/246 (46%), Gaps = 16/246 (6%)
Query: 3 VYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEV--EELGKAIDGVRALGISGLNVTM 60
+ LIG S S+ + HN F + G+ Y+ + +EL K +R G++VT
Sbjct: 216 ICALIGD-TSRSIGHLTHNPFFSQLGVACPYIKLPLTPQELPKFFSTIRTQPFLGVSVTS 274
Query: 61 PYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKAL-ERFTEIEGRNVL 119
P K V FLD+ + + S NT++ +G + G+ TDG G L + + + V
Sbjct: 275 PLKTAVLPFLDKQAPSVKASGSCNTLVIRQGEIEGHDTDGEGLFSVLMQHQIPLNNQRVA 334
Query: 120 ILGAGGAGKAIAYELSKI-ANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNYVGWADVLI 177
I+GAGGA ++IA LS+ +++ NRT + A+ L + K SL+ELP + ++I
Sbjct: 335 IIGAGGAAQSIATRLSRANCELLIFNRTKAHAEDLASRCQAKAFSLEELP--LHRVSLII 392
Query: 178 NATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQGA 237
N +++ P V+DI P + + A S G +I G M Q
Sbjct: 393 NCLPPSCTIPKAVAP--------CVVDINTIPKHSTFTQYARSQGSSIIYGHEMFTQQAL 444
Query: 238 ESFKLW 243
F+LW
Sbjct: 445 LQFRLW 450
>emb|CAA13295.1| (AJ232292) shikimate dehydrogenase [Streptococcus pneumoniae]
Length = 135
Score = 93.2 bits (228), Expect = 3e-18
Identities = 50/118 (42%), Positives = 75/118 (63%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + +R + G+N++MPYKE V +LD+LS++A I +VNT++N G+LIGY
Sbjct: 1 EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEAHLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKCLPSFT-ISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKT 117
>gb|AAD28452.1|AF127374_7 (AF127374) MitT [Streptomyces lavendulae]
Length = 270
Score = 91.7 bits (224), Expect = 8e-18
Identities = 78/246 (31%), Positives = 126/246 (50%), Gaps = 13/246 (5%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVE--ELGKAIDGVRALG-ISGLNV 58
++Y ++G PV+ +P + N L + G+DAV V V +L + ++G++ +G + GL V
Sbjct: 15 RLYAVLGDPVAQVKAPGLLNPLLSESGLDAVVVPVHVRARDLAEVVEGLKRIGNLDGLLV 74
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIINL-EGSLIGYTTDGVGARKALERFTE-IEGR 116
T+P+K + D L A I + N + +G DG+G + L+ + R
Sbjct: 75 TVPHKAALCGLADGLGPAAALIGTANAMRREPDGRWYAENFDGLGFVQGLQAAGHTVRDR 134
Query: 117 NVLILGAGGAGKAIAYEL--SKIANIVV--LNRTPSKAKSLEKFGVKGGSLDEL-PNYVG 171
+V ++GAGGAG AIA L + A + V +R A L + + L P +
Sbjct: 135 HVALVGAGGAGSAIATALLMADAARVSVHDTDRAQLDALLLRLGSRRPDGIRALGPGDLE 194
Query: 172 WADVLINATSVGMGTNESLV--PRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGL 229
AD +NAT +GM + + L P R+ R + +V+D+V KP +T LL A + G RV G+
Sbjct: 195 AADFAVNATPLGMRSEDPLPFDPARV-RPDAVVVDVVMKPHETALLSAAATAGRRVHHGI 253
Query: 230 WMLIYQ 235
ML Q
Sbjct: 254 HMLEQQ 259
>emb|CAB76615.1| (AJ271277) shikimate dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 90.1 bits (220), Expect = 2e-17
Identities = 52/152 (34%), Positives = 83/152 (54%), Gaps = 6/152 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDHVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKSLEKFGVKGGSLDELPNYV 170
+ V NRT ++ +S + SL++ Y+
Sbjct: 122 KLTVANRTMARFESW-NLNINQISLEDAEKYL 152
>emb|CAB76612.1| (AJ271274) shikimate dehydrogenease [Staphylococcus aureus]
>gi|7161993|emb|CAB76617.1| (AJ271279) shikimate
dehydrogenease [Staphylococcus aureus]
>gi|7161995|emb|CAB76618.1| (AJ271280) shikimate
dehydrogenease [Staphylococcus aureus]
>gi|7162005|emb|CAB76623.1| (AJ271286) shikimate
dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 89.7 bits (219), Expect = 3e-17
Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDHVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>emb|CAB76616.1| (AJ271278) shikimate dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 89.7 bits (219), Expect = 3e-17
Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDHVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>emb|CAB76620.1| (AJ271283) shikimate dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 89.7 bits (219), Expect = 3e-17
Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDHVDEQAINTG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>emb|CAB76626.1| (AJ271289) shikimate dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 89.7 bits (219), Expect = 3e-17
Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDHVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKL 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>emb|CAB76613.1| (AJ271275) shikimate dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 88.9 bits (217), Expect = 5e-17
Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELEGFNITIPHKERIIPYLDYVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>emb|CAB76614.1| (AJ271276) shikimate dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 88.9 bits (217), Expect = 5e-17
Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDYVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>emb|CAB76619.1| (AJ271281) shikimate dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 88.9 bits (217), Expect = 5e-17
Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDYVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>emb|CAA13280.1| (AJ232277) shikimate dehydrogenase [Streptococcus mitis]
Length = 135
Score = 88.5 bits (216), Expect = 7e-17
Identities = 49/118 (41%), Positives = 74/118 (62%), Gaps = 3/118 (2%)
Query: 37 EVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGY 96
E +L + + + + G+N++MPYKE V +LD LS++ R I +VNT++N G+LIGY
Sbjct: 1 EAGDLAETVANICRYQMFGINLSMPYKEQVIPYLDGLSDEVRLIGAVNTVVNENGNLIGY 60
Query: 97 TTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAYE--LSKIANIVVLNRTPSKAKS 152
TDG G K+L FT I G+ + +LGAGGA K+I + L ++ I V R+ S K+
Sbjct: 61 NTDGKGFFKSLPSFT-ITGKKMTLLGAGGAAKSIIAQAILDGVSQISVFVRSVSMEKT 117
>emb|CAB76625.1| (AJ271288) shikimate dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 88.5 bits (216), Expect = 7e-17
Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDNYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDHVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>emb|CAB76611.1| (AJ271273) shikimate dehydrogenase [Staphylococcus aureus]
Length = 152
Score = 87.0 bits (212), Expect = 2e-16
Identities = 48/134 (35%), Positives = 75/134 (55%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+P+KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDHVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ + IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDDKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>emb|CAB76622.1| (AJ271285) shikimate dehydrogenease [Staphylococcus aureus]
>gi|7162007|emb|CAB76624.1| (AJ271287) shikimate
dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 87.0 bits (212), Expect = 2e-16
Identities = 44/103 (42%), Positives = 65/103 (62%), Gaps = 3/103 (2%)
Query: 53 ISGLNVTMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALER-FT 111
+ G N+T+P+KE + +LD + E A +VNT++ +G IGY TDG+G K L +
Sbjct: 33 LDGFNITIPHKERIISYLDHVDEQAINAGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYP 92
Query: 112 EIEGRNVLILGAGGAGKAIAYELSKIA--NIVVLNRTPSKAKS 152
++E +LILGAGGA K IAYEL+K + V NRT ++ +S
Sbjct: 93 DLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFES 135
>emb|CAB76621.1| (AJ271284) shikimate dehydrogenease [Staphylococcus aureus]
Length = 152
Score = 86.6 bits (211), Expect = 3e-16
Identities = 48/134 (35%), Positives = 75/134 (55%), Gaps = 5/134 (3%)
Query: 24 FRKYGIDAVY--VTFEVEELGKAIDGVRALGISGLNVTMPYKEVVTKFLDELSEDAREIN 81
F G+D Y + +E+ + + + G N+T+ +KE + +LD + E A
Sbjct: 2 FNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITISHKERIIPYLDHVDEQAINAG 61
Query: 82 SVNTIINLEGSLIGYTTDGVGARKALER-FTEIEGRNVLILGAGGAGKAIAYELSKIA-- 138
+VNT++ +G IGY TDG+G K L + ++E +LILGAGGA K IAYEL+K
Sbjct: 62 AVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKP 121
Query: 139 NIVVLNRTPSKAKS 152
+ V NRT ++ +S
Sbjct: 122 KLTVANRTMARFES 135
>pir||D70660 probable aroE - Mycobacterium tuberculosis (strain H37RV)
>gi|1781050|emb|CAB06186.1| (Z83863) aroE [Mycobacterium
tuberculosis]
Length = 269
Score = 85.8 bits (209), Expect = 5e-16
Identities = 77/269 (28%), Positives = 118/269 (43%), Gaps = 30/269 (11%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGI-DAVYVTFE--VEELGKAIDGVRALGISGLNV 58
K G++G P++HS SP +H A +R G+ D Y E EL + G + G++V
Sbjct: 6 KKAGVLGSPIAHSRSPQLHLAAYRALGLHDWTYERIECGAAELPVVVGGFGPEWV-GVSV 64
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIINLEGSLIGYTTDGVGARKALERFTEIEGRNV 118
TMP K +F DE + A + S NT++ TD G AL +
Sbjct: 65 TMPGKFAALRFADERTARADLVGSANTLVRTPHGWRADNTDIDGVAGALGA----AAGHA 120
Query: 119 LILGAGGAGKAIAYELSK--IANIVVLNRTPSKAKSLEKFGVKGGSLDE--------LPN 168
L+LG+GG A L++ + +I V+ R KA L G + G L +
Sbjct: 121 LVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATRFCAFDSGGLAD 180
Query: 169 YVGWADVLINA----TSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR 224
V A+VL++ + G + +P +++D +Y P T L S G R
Sbjct: 181 AVAAAEVLVSTIPAEVAAGYAGTLAAIP--------VLLDAIYDPWPTPLAAAVGSAGGR 232
Query: 225 VIDGLWMLIYQGAESFKLWTGIYPDVELM 253
VI GL ML++Q + +TG+ E M
Sbjct: 233 VISGLQMLLHQAFAQVEQFTGLPAPREAM 261
>gb|AAC08642.1| (AF037792) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 83.5 bits (203), Expect = 2e-15
Identities = 53/144 (36%), Positives = 78/144 (53%), Gaps = 7/144 (4%)
Query: 111 TEIEGRNVLILGAGGAGKAIAYEL--SKIANIVVLNRTPSKAKSL-EKFGVKGGSLDELP 167
TEIEG+N+L+LGAGGA + + L A IV+ NRT +KA+ + +FG++ S D L
Sbjct: 13 TEIEGKNILLLGAGGAVRGVIPVLLAQNPARIVIANRTRAKAEEVAARFGIEAVSPDSL- 71
Query: 168 NYVGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR-VI 226
G D+++N TS G+ +P + + + D+VY L A G +
Sbjct: 72 --AGGFDIIVNGTSGGLSGQIPDIPPDIFQNCALAYDMVYGEAAKPFLDFARQSGAKQTA 129
Query: 227 DGLWMLIYQGAESFKLWTGIYPDV 250
DGL ML+ Q A S+ LW G PD+
Sbjct: 130 DGLGMLVGQAAASYALWRGFKPDI 153
>gb|AAC08635.1| (AF037785) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 82.3 bits (200), Expect = 5e-15
Identities = 53/144 (36%), Positives = 79/144 (54%), Gaps = 7/144 (4%)
Query: 111 TEIEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELP 167
TEIEG+N+L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + +L
Sbjct: 13 TEIEGKNILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELSRLFGIEAVPMADLN 72
Query: 168 NYVGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVI 226
G D++IN TS G+ +P + + + D+VY L A G +
Sbjct: 73 ---GGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTA 129
Query: 227 DGLWMLIYQGAESFKLWTGIYPDV 250
DGL ML+ Q A S+ LW G PD+
Sbjct: 130 DGLGMLVGQAAASYALWRGFTPDI 153
>gb|AAC08640.1| (AF037790) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 82.3 bits (200), Expect = 5e-15
Identities = 53/144 (36%), Positives = 79/144 (54%), Gaps = 7/144 (4%)
Query: 111 TEIEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELP 167
TEIEG+N+L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + +L
Sbjct: 13 TEIEGKNILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELSRLFGIEAVPMADLN 72
Query: 168 NYVGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVI 226
G D++IN TS G+ +P + + + D+VY L A G +
Sbjct: 73 ---GGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTA 129
Query: 227 DGLWMLIYQGAESFKLWTGIYPDV 250
DGL ML+ Q A S+ LW G PD+
Sbjct: 130 DGLGMLVGQAAASYALWRGFTPDI 153
>gb|AAC08647.1| (AF037797) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 81.1 bits (197), Expect = 1e-14
Identities = 52/142 (36%), Positives = 78/142 (54%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTHAKAEELARLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDG 228
G D++IN TS G+ V R + R + D+VY L A+S G V DG
Sbjct: 73 -GGFDIIINGTSGGLSGQLPAVSREIFRNCRLAYDMVYGDAAQAFLNFAQSNGAAEVSDG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ +W G PD+
Sbjct: 132 LGMLVGQAAASYHIWRGFTPDI 153
>sp|P25415|DHQA_EMENI QUINATE 5-DEHYDROGENASE >gi|2401|emb|CAA31880.1| (X13525) quinate
dehydrogenase [Aspergillus nidulellus]
Length = 329
Score = 80.8 bits (196), Expect = 2e-14
Identities = 77/288 (26%), Positives = 127/288 (43%), Gaps = 51/288 (17%)
Query: 6 LIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVE---------ELGKAIDGVRALG-ISG 55
L G P+ +SLSP +H ++ G++ + E+ + VR+ G
Sbjct: 16 LYGHPLPNSLSPPLHQTVYNALGLNWTQIPLSTATGTSFTRSPEISTFLSSVRSNPKFVG 75
Query: 56 LNVTMPYKEVVTKFLDELSEDAREINSVNTII-----NLEGSLIGYTTDGVGARKALERF 110
+VTMP+K + LD+L+EDAR+ + NTI + + +G TD +G R+AL +
Sbjct: 76 SSVTMPWKVAIMPHLDDLTEDARQAGACNTIYLRKEDDGKTQYVGTNTDCIGIREALLQG 135
Query: 111 T-----EIEGRNVLILGAGGAGKAIAYELSK---IANIVVLNRTPSKAKSLEKFGVKGGS 162
+ +G+ LI+G GG + Y L K ++ I ++NR AK +E +
Sbjct: 136 SPNGAEHFKGKPALIVGGGGTARTAIYVLRKWLGVSKIYIVNRD---AKEVEAILAEDKQ 192
Query: 163 LDELPNYV-------GWADVLINATSVGMG-------TNESLVPRRLLRREL-------- 200
+ P A L +V G T E + R LR L
Sbjct: 193 RNPSPQVALVPVSDPSAAATLEAPVAVVSGIPNYPPQTEEEIRARETLRLFLNRQTHEKD 252
Query: 201 --IVMDIVYKPLK-TRLLRDAESVGCRVIDGLWMLIYQGAESFKLWTG 245
+++++ Y PL T + + A+ +VI G LI+QG E ++WTG
Sbjct: 253 QGVILEMCYHPLPWTDIAQIAQDARWKVILGSEALIWQGLEQARVWTG 300
>pir||S08499 quinate 5-dehydrogenase (EC 1.1.1.24) - Emericella nidulans
Length = 329
Score = 80.8 bits (196), Expect = 2e-14
Identities = 77/288 (26%), Positives = 127/288 (43%), Gaps = 51/288 (17%)
Query: 6 LIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVE---------ELGKAIDGVRALG-ISG 55
L G P+ +SLSP +H ++ G++ + E+ + VR+ G
Sbjct: 16 LYGHPLRNSLSPPLHQTVYNALGLNWTQIPLSTATGTSFTRSPEISTFLSSVRSNPKFVG 75
Query: 56 LNVTMPYKEVVTKFLDELSEDAREINSVNTII-----NLEGSLIGYTTDGVGARKALERF 110
+VTMP+K + LD+L+EDAR+ + NTI + + +G TD +G R+AL +
Sbjct: 76 SSVTMPWKVAIMPHLDDLTEDARQAGACNTIYLRKEDDGKTQYVGTNTDCIGIREALLQG 135
Query: 111 T-----EIEGRNVLILGAGGAGKAIAYELSK---IANIVVLNRTPSKAKSLEKFGVKGGS 162
+ +G+ LI+G GG + Y L K ++ I ++NR AK +E +
Sbjct: 136 SPNGAEHFKGKPALIVGGGGTARTAIYVLRKWLGVSKIYIVNRD---AKEVEAILAEDKQ 192
Query: 163 LDELPNYV-------GWADVLINATSVGMG-------TNESLVPRRLLRREL-------- 200
+ P A L +V G T E + R LR L
Sbjct: 193 RNPSPQVALVPVSDPSAAATLEAPVAVVSGIPNYPPQTEEEIRARETLRLFLNRQTHEKD 252
Query: 201 --IVMDIVYKPLK-TRLLRDAESVGCRVIDGLWMLIYQGAESFKLWTG 245
+++++ Y PL T + + A+ +VI G LI+QG E ++WTG
Sbjct: 253 QGVILEMCYHPLPWTDIAQIAQDARWKVILGSEALIWQGLEQARVWTG 300
>gb|AAC01719.1| (AF040570) aminoquinate/shkimate dehydrogenase [Amycolatopsis
mediterranei]
Length = 263
Score = 80.8 bits (196), Expect = 2e-14
Identities = 79/258 (30%), Positives = 123/258 (47%), Gaps = 16/258 (6%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVE--ELGKAIDGVRALG-ISGLNV 58
++Y ++G PV+ SP + N LF +DAV V L + + G++A+ + G+ V
Sbjct: 8 RLYVVLGDPVAQVRSPGLLNPLFADLDVDAVLVPVHAPPPHLERIVAGLQAVANLDGIFV 67
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTIIN-LEGSLIGYTTDGVGARKAL-ERFTEIEGR 116
T+P+K V D S S N + +G DG G L E + + R
Sbjct: 68 TVPHKVAVAGLADRRSPMVEITGSANALRREADGRWYAENFDGTGFVAGLVEAGHDPKAR 127
Query: 117 NVLILGAGGAGKAIAYELSKIANIVVLNRTPSKAK------SLEKFGVKGGSLDELPNYV 170
V ++GAGGAG AIA + + P AK L+ S+ P+
Sbjct: 128 RVSLVGAGGAGSAIAAAVLAAGADRLALCDPDTAKLAALKGRLDVHWPGRTSVSAEPDTA 187
Query: 171 GWADVLINATSVGMGTNESLV--PRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDG 228
G AD+++NAT +G+ + L P RL +V DI+ KP +TRLLR+A ++G V G
Sbjct: 188 G-ADLVVNATPLGLRPGDPLPFRPDRLAPGR-VVADIIMKPRETRLLREAAALGHDVHYG 245
Query: 229 LWMLIYQGAESFKLWTGI 246
ML Q +S++ + G+
Sbjct: 246 SHMLAGQ-LDSYRDFFGL 262
>gb|AAF97082.1|AF267542_1 (AF267542) shikimate dehydrogenase [Escherichia coli]
>gi|9664362|gb|AAF97083.1|AF267543_1 (AF267543)
shikimate dehydrogenase [Escherichia coli]
Length = 152
Score = 80.4 bits (195), Expect = 2e-14
Identities = 56/153 (36%), Positives = 83/153 (53%), Gaps = 10/153 (6%)
Query: 71 DELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GRNVLILGAGGAGK 128
DEL+E A +VNT++ LE G L+G TDGVG LER + I G +L++GAGGA +
Sbjct: 1 DELTERAALAGAVNTLMRLENGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASR 60
Query: 129 AIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYVGWADVLINATSV 182
+ L + + + NRT S+A+ L K GS+ DEL + D++INATS
Sbjct: 61 GVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHE--FDLIINATSS 118
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLL 215
G+ + +P L+ + D+ Y+ KT L
Sbjct: 119 GISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFL 151
>gb|AAF97084.1|AF267544_1 (AF267544) shikimate dehydrogenase [Escherichia coli]
>gi|9664366|gb|AAF97085.1|AF267545_1 (AF267545)
shikimate dehydrogenase [Escherichia coli]
Length = 152
Score = 78.8 bits (191), Expect = 6e-14
Identities = 56/153 (36%), Positives = 82/153 (52%), Gaps = 10/153 (6%)
Query: 71 DELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GRNVLILGAGGAGK 128
DEL+E A +VNT+ LE G L+G TDGVG LER + I G +L++GAGGA +
Sbjct: 1 DELTERAALAGAVNTLKRLENGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASR 60
Query: 129 AIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYVGWADVLINATSV 182
+ L + + + NRT S+A+ L K GS+ DEL + D++INATS
Sbjct: 61 GVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHE--FDLIINATSS 118
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLL 215
G+ + +P L+ + D+ Y+ KT L
Sbjct: 119 GISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFL 151
>gb|AAF97086.1|AF267546_1 (AF267546) shikimate dehydrogenase [Escherichia coli]
Length = 152
Score = 78.8 bits (191), Expect = 6e-14
Identities = 56/153 (36%), Positives = 82/153 (52%), Gaps = 10/153 (6%)
Query: 71 DELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GRNVLILGAGGAGK 128
DEL+E A +VNT+ LE G L+G TDGVG LER + I G +L++GAGGA +
Sbjct: 1 DELTERAALAGAVNTLKRLENGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASR 60
Query: 129 AIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYVGWADVLINATSV 182
+ L + + + NRT S+A+ L K GS+ DEL + D++INATS
Sbjct: 61 GVLLPLLSLDCAVTITNRTVSRAEKLAKLFAHTGSIQALGMDELEGHE--FDLIINATSS 118
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLL 215
G+ + +P L+ + D+ Y+ KT L
Sbjct: 119 GISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFL 151
>gb|AAC08646.1| (AF037796) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 78.4 bits (190), Expect = 8e-14
Identities = 52/142 (36%), Positives = 76/142 (52%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + IV+ NRT +KA+ L + FG++ + +L
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPTRIVIANRTHAKAEELAQLFGIEAVPMADLN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDG 228
G D++IN TS G+ V + R + D+VY L A+S G V DG
Sbjct: 73 -GGFDIIINGTSGGLSGQLPAVNPEIFRNCRLAYDMVYGDAAQAFLNFAQSNGAAEVSDG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYSLWRGFKPDI 153
>gb|AAF97088.1|AF267548_1 (AF267548) shikimate dehydrogenase [Escherichia coli]
>gi|9664374|gb|AAF97089.1|AF267549_1 (AF267549)
shikimate dehydrogenase [Escherichia coli]
>gi|9664382|gb|AAF97093.1|AF267553_1 (AF267553)
shikimate dehydrogenase [Escherichia coli]
>gi|9664384|gb|AAF97094.1|AF267554_1 (AF267554)
shikimate dehydrogenase [Escherichia coli]
>gi|9664386|gb|AAF97095.1|AF267555_1 (AF267555)
shikimate dehydrogenase [Escherichia coli]
>gi|9664388|gb|AAF97096.1|AF267556_1 (AF267556)
shikimate dehydrogenase [Escherichia coli]
Length = 152
Score = 78.4 bits (190), Expect = 8e-14
Identities = 55/153 (35%), Positives = 82/153 (52%), Gaps = 10/153 (6%)
Query: 71 DELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GRNVLILGAGGAGK 128
DEL+E A +VNT+ LE G L+G TDG+G LER + I G +L++GAGGA +
Sbjct: 1 DELTERAALAGAVNTLKRLENGRLLGDNTDGIGLLSDLERLSFIRPGLRILLIGAGGASR 60
Query: 129 AIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYVGWADVLINATSV 182
+ L + + + NRT S+A+ L K GS+ DEL + D++INATS
Sbjct: 61 GVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHE--FDLIINATSS 118
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLL 215
G+ + +P L+ + D+ Y+ KT L
Sbjct: 119 GISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFL 151
>gb|AAF97098.1|AF267558_1 (AF267558) shikimate dehydrogenase [Escherichia coli]
Length = 152
Score = 78.4 bits (190), Expect = 8e-14
Identities = 55/153 (35%), Positives = 82/153 (52%), Gaps = 10/153 (6%)
Query: 71 DELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GRNVLILGAGGAGK 128
DEL+E A +VNT+ LE G L+G TDG+G LER + I G +L++GAGGA +
Sbjct: 1 DELTERAALAGAVNTLKRLENGRLLGDNTDGIGLLSDLERLSFIRPGLRILLIGAGGASR 60
Query: 129 AIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYVGWADVLINATSV 182
+ L + + + NRT S+A+ L K GS+ DEL + D++INATS
Sbjct: 61 GVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIHALGMDELEGHE--FDLIINATSS 118
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLL 215
G+ + +P L+ + D+ Y+ KT L
Sbjct: 119 GISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFL 151
>sp|P07547|ARO1_EMENI PENTAFUNCTIONAL AROM POLYPEPTIDE [INCLUDES: 3-DEHYDROQUINATE SYNTHASE
; 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE);
SHIKIMATE 5-DEHYDROGENASE ; SHIKIMATE KINASE ;
3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE
(5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYN>
>gi|3834343|emb|CAA28836.1| (X05204) arom polypeptide
[Emericella nidulans]
Length = 1586
Score = 78.0 bits (189), Expect = 1e-13
Identities = 69/269 (25%), Positives = 120/269 (43%), Gaps = 34/269 (12%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMP 61
K + + G P+S S SP +HN LF + G+ Y E + +R+ G
Sbjct: 1291 KKFAIFGSPISQSRSPALHNTLFAQVGLPHNYTRLETTNAQDVQEFIRSPDFGGAFRNNS 1350
Query: 62 YKEVVTKFLDELSEDAREINSVNTII------NLEGSLIGYTTDGVGARKALERF----- 110
K + LDE++ +A I +VNTII N L+G TD G +L +
Sbjct: 1351 LKLDIMPLLDEVAAEAEIIGAVNTIIPVSTGKNTPSRLVGRNTDWQGMILSLRKAGVYGP 1410
Query: 111 -TEIEGRNVLILGAGGAGKAIAYELSKI--ANIVVLNRTPSKAKSL-----EKFGVK--- 159
+ + ++ L++G GG +A Y L + + I ++ RTPSK +++ + ++
Sbjct: 1411 KRKDQEQSALVVGGGGTARAAIYALHNMGYSPIYIVGRTPSKLENMVSTFPSSYNIRIVE 1470
Query: 160 -GGSLDELPNY-VGW--ADVLINATS--------VGMGTNESLVPRRLLRRELIVMDIVY 207
S + +P+ +G AD I+ T ++ + + I++++ Y
Sbjct: 1471 SPSSFESVPHVAIGTIPADQPIDPTMRETLCHMFERAQEADAEAVKAIEHAPRILLEMAY 1530
Query: 208 KPLKTRLLRDAESVGCRVIDGLWMLIYQG 236
KP T L+R A G + I GL +L+ QG
Sbjct: 1531 KPQVTALMRLASDSGWKTIPGLEVLVGQG 1559
>gb|AAF97087.1|AF267547_1 (AF267547) shikimate dehydrogenase [Escherichia coli]
>gi|9664390|gb|AAF97097.1|AF267557_1 (AF267557)
shikimate dehydrogenase [Escherichia coli]
Length = 152
Score = 76.9 bits (186), Expect = 2e-13
Identities = 54/153 (35%), Positives = 82/153 (53%), Gaps = 10/153 (6%)
Query: 71 DELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GRNVLILGAGGAGK 128
DEL+E A +VNT+ L+ G L+G TDG+G LER + I G +L++GAGGA +
Sbjct: 1 DELTERAALAGAVNTLKRLKNGRLLGDNTDGIGLLSDLERLSFIRPGLRILLIGAGGASR 60
Query: 129 AIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYVGWADVLINATSV 182
+ L + + + NRT S+A+ L K GS+ DEL + D++INATS
Sbjct: 61 GVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHE--FDLIINATSS 118
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLL 215
G+ + +P L+ + D+ Y+ KT L
Sbjct: 119 GISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFL 151
>gb|AAC08636.1| (AF037786) shikimate dehydrogenase [Neisseria meningitidis]
>gi|2745793|gb|AAC08637.1| (AF037787) shikimate
dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 76.5 bits (185), Expect = 3e-13
Identities = 52/142 (36%), Positives = 76/142 (52%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IVV NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKGHRPARIVVANRTHAKAEELARLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDG 228
G D++IN TS G+ V + + D+VY L A+S G V DG
Sbjct: 73 -GGFDIIINGTSGGLSGQLPAVSPEIFLGCRLAYDMVYGDAAQEFLNFAQSNGAAEVSDG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYALWRGFTPDI 153
>gb|AAC08641.1| (AF037791) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 76.5 bits (185), Expect = 3e-13
Identities = 52/142 (36%), Positives = 76/142 (52%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IVV NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVVANRTHAKAEELARLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDG 228
G D++IN TS G+ V + + D+VY L A+S G V DG
Sbjct: 73 -GGFDIIINGTSGGLSGQLPAVSPEIFLGCRLAYDMVYGDAAQEFLNFAQSNGAAEVSDG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYALWRGFTPDI 153
>gb|AAC08630.1| (AF037780) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 76.1 bits (184), Expect = 4e-13
Identities = 51/142 (35%), Positives = 76/142 (52%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTHAKAEELARLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVG-CRVIDG 228
G D++IN TS G+ V + + D+VY L A+S G V DG
Sbjct: 73 -GGFDIIINGTSGGLSGQLPAVSPEIFLGCRLAYDMVYGDAAQEFLNFAQSNGAAEVSDG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYALWRGFTPDI 153
>gb|AAC08639.1| (AF037789) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 75.7 bits (183), Expect = 5e-13
Identities = 49/142 (34%), Positives = 76/142 (53%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSLEK-FGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELSRLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDG 228
G D++IN TS G+ +P + + + D+VY L A G + DG
Sbjct: 73 -GGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYSCAAKPFLDFARQSGAKKTADG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYALWRGFTPDI 153
>gb|AAC08644.1| (AF037794) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 75.3 bits (182), Expect = 7e-13
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + +L
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADLN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDG 228
G D++IN TS G+ +P + + + D+VY L A G + DG
Sbjct: 73 -GGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYALWRGFTPDI 153
>gb|AAF97079.1|AF267539_1 (AF267539) shikimate dehydrogenase [Escherichia coli]
>gi|9664356|gb|AAF97080.1|AF267540_1 (AF267540)
shikimate dehydrogenase [Escherichia coli]
>gi|9664358|gb|AAF97081.1|AF267541_1 (AF267541)
shikimate dehydrogenase [Escherichia coli]
Length = 152
Score = 74.9 bits (181), Expect = 9e-13
Identities = 54/153 (35%), Positives = 81/153 (52%), Gaps = 10/153 (6%)
Query: 71 DELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GRNVLILGAGGAGK 128
DEL+E A +VNT+ LE G L+G TDGVG LER + I G +L++GAGGA +
Sbjct: 1 DELTERAALAGAVNTLKRLENGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASR 60
Query: 129 AIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYVGWADVLINATSV 182
+ L + + + NRT +A+ L K GS+ D+L + D++INATS
Sbjct: 61 GVLLPLLSLDCAVTITNRTVFRAEELAKLFAHTGSIQALGMDKLEGHE--FDLIINATSS 118
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLL 215
G+ + +P L+ + D+ Y+ KT L
Sbjct: 119 GISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFL 151
>gb|AAF97091.1|AF267551_1 (AF267551) shikimate dehydrogenase [Escherichia coli]
>gi|9664380|gb|AAF97092.1|AF267552_1 (AF267552)
shikimate dehydrogenase [Escherichia coli]
Length = 152
Score = 74.9 bits (181), Expect = 9e-13
Identities = 54/153 (35%), Positives = 81/153 (52%), Gaps = 10/153 (6%)
Query: 71 DELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GRNVLILGAGGAGK 128
DEL+E A +VNT+ L+ G L G TDG+G LER + I G +L++GAGGA +
Sbjct: 1 DELTERAALAGAVNTLKRLKNGRLQGDNTDGIGLLSDLERLSFIRPGLRILLIGAGGASR 60
Query: 129 AIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYVGWADVLINATSV 182
+ L + + + NRT S+A+ L K GS+ DEL + D++INATS
Sbjct: 61 GVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHE--FDLIINATSS 118
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLL 215
G+ + +P L+ + D+ Y+ KT L
Sbjct: 119 GISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFL 151
>gb|AAC08631.1| (AF037781) shikimate dehydrogenase [Neisseria meningitidis]
>gi|2745787|gb|AAC08634.1| (AF037784) shikimate
dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 74.1 bits (179), Expect = 2e-12
Identities = 49/142 (34%), Positives = 76/142 (53%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDG 228
G D++IN TS G+ +P + + + D+VY L A G + DG
Sbjct: 73 -GGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYALWRGFTPDI 153
>gb|AAC08632.1| (AF037782) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 74.1 bits (179), Expect = 2e-12
Identities = 49/142 (34%), Positives = 76/142 (53%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDG 228
G D++IN TS G+ +P + + + D+VY L A G + DG
Sbjct: 73 -GGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYALWRGFTPDI 153
>gb|AAC08633.1| (AF037783) shikimate dehydrogenase [Neisseria meningitidis]
>gi|2745805|gb|AAC08643.1| (AF037793) shikimate
dehydrogenase [Neisseria meningitidis]
>gi|2745809|gb|AAC08645.1| (AF037795) shikimate
dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 74.1 bits (179), Expect = 2e-12
Identities = 49/142 (34%), Positives = 76/142 (53%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDG 228
G D++IN TS G+ +P + + + D+VY L A G + DG
Sbjct: 73 -GGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYALWRGFTPDI 153
>gb|AAD50802.1| (AF165316) shikimate dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 74.1 bits (179), Expect = 2e-12
Identities = 49/142 (34%), Positives = 76/142 (53%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTHAKAEELAQLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGC-RVIDG 228
G D++IN TS G+ +P + + + D+VY L A G + DG
Sbjct: 73 -GGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G PD+
Sbjct: 132 LGMLVGQAAASYALWRGFTPDI 153
>gb|AAD31827.1| (AF131877) shikimate/quinate dehydrogenase [Streptomyces collinus]
Length = 280
Score = 73.7 bits (178), Expect = 2e-12
Identities = 72/259 (27%), Positives = 123/259 (46%), Gaps = 16/259 (6%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVE--ELGKAIDGVRALG-ISGLNV 58
++Y ++G PV SP + N LF + GIDAV V V +L + G++ +G + GL V
Sbjct: 23 RLYAVLGDPVGQVQSPGLLNPLFARLGIDAVLVPVHVRPADLEPVVRGLQRVGNLDGLFV 82
Query: 59 TMPYKEVVTKFLDELSEDAREINSVNTI-INLEGSLIGYTTDGVGARKAL-ERFTEIEGR 116
T+P+K D S S N + +G+ + DG G L + + +G
Sbjct: 83 TVPHKTAAALLADRRSPTVEITGSANALRREPDGTWLAENFDGSGFVAGLAQAGHQPKGA 142
Query: 117 NVLILGAGGAGKAIAYE-LSKIANIVVLN--RTPSKAKSLEKFGV----KGGSLDELPNY 169
V ++GAGGAG AIA L+ A+ + L TP +++ + + E P
Sbjct: 143 RVALVGAGGAGSAIAAALLAAGADRLTLTDPDTPRLTALVDRLAAHWPGRVRAAGEPP-- 200
Query: 170 VGWADVLINATSVGMGTNE-SLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDG 228
+ +++ +NAT +G+ + +P I+ KP +TRLL +A++ G G
Sbjct: 201 LADSEIAVNATPLGLRPRRPAALPAARAATGRRCCRIIMKPRETRLLGEADAHGIHTHHG 260
Query: 229 LWMLIYQGAESFKLWTGIY 247
ML Q +S++ + G++
Sbjct: 261 RHMLTGQ-IDSYRAFFGLH 278
>gb|AAF97090.1|AF267550_1 (AF267550) shikimate dehydrogenase [Escherichia coli]
Length = 152
Score = 73.7 bits (178), Expect = 2e-12
Identities = 54/153 (35%), Positives = 81/153 (52%), Gaps = 10/153 (6%)
Query: 71 DELSEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIE-GRNVLILGAGGAGK 128
DEL+E A +VNT+ L+ G L G TDG+G LER + I G +L++GAGGA +
Sbjct: 1 DELTERAALAGAVNTLKRLKNGRLQGDNTDGIGLLSNLERLSFIRPGLLILLIGAGGASR 60
Query: 129 AIAYELSKI-ANIVVLNRTPSKAKSLEKFGVKGGSL-----DELPNYVGWADVLINATSV 182
+ L + + + NRT S+A+ L K GS+ DEL + D++INATS
Sbjct: 61 GVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHE--FDLIINATSS 118
Query: 183 GMGTNESLVPRRLLRRELIVMDIVYKPLKTRLL 215
G+ + +P L+ + D+ Y+ KT L
Sbjct: 119 GISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFL 151
>pir||S48698 3-dehydroquinate dehydratase (EC 4.2.1.10) / shikimate
5-dehydrogenase (EC 1.1.1.25) precursor - garden pea
(fragment)
Length = 325
Score = 73.0 bits (176), Expect = 4e-12
Identities = 35/86 (40%), Positives = 52/86 (59%)
Query: 2 KVYGLIGKPVSHSLSPVMHNALFRKYGIDAVYVTFEVEELGKAIDGVRALGISGLNVTMP 61
KVYG+IGKPVSHS SP++ N F+ G + V+V V++L + + G +VT+P
Sbjct: 236 KVYGIIGKPVSHSKSPILFNEAFKTVGFNGVFVFLLVDDLANFLRTYSSTDFVGFSVTIP 295
Query: 62 YKEVVTKFLDELSEDAREINSVNTII 87
+KE K DE+ A+ I +VN I+
Sbjct: 296 HKESALKCCDEVDPVAKSIGAVNXIV 321
>gb|AAC08638.1| (AF037788) shikimate dehydrogenase [Neisseria meningitidis]
>gi|5758358|gb|AAD50801.1| (AF165315) shikimate
dehydrogenase [Neisseria meningitidis]
Length = 163
Score = 72.2 bits (174), Expect = 6e-12
Identities = 49/142 (34%), Positives = 75/142 (52%), Gaps = 7/142 (4%)
Query: 113 IEGRNVLILGAGGAGKAIAYELS--KIANIVVLNRTPSKAKSL-EKFGVKGGSLDELPNY 169
IEG+ +L+LGAGGA + + L + A IV+ NRT +KA+ L + FG++ + ++
Sbjct: 15 IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTHAKAEELAQLFGIEAVPMADVN-- 72
Query: 170 VGWADVLINATSVGMGTNESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCR-VIDG 228
G D++IN TS G+ V + R + D+VY L A G + DG
Sbjct: 73 -GGFDIIINGTSGGLSGQLPAVNPEIFRDCRLAYDMVYGEAAKPFLDFARQSGAKQTADG 131
Query: 229 LWMLIYQGAESFKLWTGIYPDV 250
L ML+ Q A S+ LW G P++
Sbjct: 132 LGMLVGQAAASYALWRGFTPNI 153
>emb|CAB93378.1| (AL357523) shikimate 5-dehydrogenase [Streptomyces coelicolor
A3(2)]
Length = 255
Score = 69.9 bits (168), Expect = 3e-11
Identities = 65/241 (26%), Positives = 112/241 (45%), Gaps = 13/241 (5%)
Query: 18 VMHNALFRKYGI-DAVYVTFEVEELGKAIDG-VRALGI--SGLNVTMPYKEVVTKFLDEL 73
++H A + + G+ D Y F+V+E A+ G + LG +GL++TMP K V LD +
Sbjct: 1 MLHRAAYAELGLADWTYDHFDVDEA--ALPGFLEGLGPEWAGLSLTMPLKRAVIPLLDSV 58
Query: 74 SEDAREINSVNTIINLE-GSLIGYTTDGVGARKALERFTEIEGRNVLILGAGGAGKAIAY 132
SE A +++VNT++ E G G TD G AL + + ILGAG +
Sbjct: 59 SETAASVDAVNTVVLTEDGRRTGDNTDIPGIAAALREHGIEKVESAAILGAGATASSALA 118
Query: 133 ELSKI--ANIVVLNRTPSKAKSLEKFGVKGGSLDELPNYVGWADVL---INATSVGMGTN 187
L++I + V R+ ++A + + + G L ++ A+ L + + G
Sbjct: 119 ALARICTGEVTVHVRSAARAAEMRGWAERLGVDVRLADWADAAEALRAPLVVATTPAGAT 178
Query: 188 ESLVPRRLLRRELIVMDIVYKPLKTRLLRDAESVGCRVIDGLWMLIYQGAESFKLWTGIY 247
++L + + D++Y P T L + G V+ GL +L++Q + TG
Sbjct: 179 DALA-AAVPEMPTTLFDVLYDPWPTALAARWSAHGGAVVSGLDLLLHQAVLQVEQMTGRA 237
Query: 248 P 248
P
Sbjct: 238 P 238
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.140 0.396
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95198934
Number of Sequences: 2977
Number of extensions: 3919896
Number of successful extensions: 12226
Number of sequences better than 1.0e-10: 117
Number of HSP's better than 0.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 11877
Number of HSP's gapped (non-prelim): 121
length of query: 264
length of database: 189,106,746
effective HSP length: 56
effective length of query: 208
effective length of database: 155,591,474
effective search space: 32363026592
effective search space used: 32363026592
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 164 (68.3 bits)