BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0301 (thrB-2) DE:HOMOSERINE KINASE
(274 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||F75161 homoserine kinase PAB0301 - Pyrococcus abyssi (strai... 536 e-151
pir||E69207 conserved hypothetical protein MTH805 - Methanobacte... 161 1e-38
pir||G64479 hypothetical protein MJ1440 - Methanococcus jannasch... 152 3e-36
gb|AAG19605.1| (AE005050) Vng1245c [Halobacterium sp. NRC-1] 150 2e-35
pir||D72642 hypothetical protein APE0572 - Aeropyrum pernix (str... 114 1e-24
emb|CAC11428.1| (AL445063) conserved hypothetical protein [Therm... 112 4e-24
gi|11498131 conserved hypothetical protein [Archaeoglobus fulgid... 111 9e-24
gb|AAK40645.1| Conserved hypothetical protein [Sulfolobus solfat... 111 1e-23
>pir||F75161 homoserine kinase PAB0301 - Pyrococcus abyssi (strain Orsay)
>gi|5457883|emb|CAB49373.1| (AJ248284) HOMOSERINE KINASE
[Pyrococcus abyssi]
Length = 274
Score = 536 bits (1366), Expect = e-151
Identities = 274/274 (100%), Positives = 274/274 (100%)
Query: 1 MRGSGRASSAITIVNAFATGKGAAIGIELWTEARVRVTGDGEVRGKIVVKGEEFKDYRLV 60
MRGSGRASSAITIVNAFATGKGAAIGIELWTEARVRVTGDGEVRGKIVVKGEEFKDYRLV
Sbjct: 1 MRGSGRASSAITIVNAFATGKGAAIGIELWTEARVRVTGDGEVRGKIVVKGEEFKDYRLV 60
Query: 61 NSVISVLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRLNIDDLSIVK 120
NSVISVLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRLNIDDLSIVK
Sbjct: 61 NSVISVLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRLNIDDLSIVK 120
Query: 121 LGVEAAKRAGVTITGAFDDACASYFGGLCITDNYEMEILVKREINPETVVLLIPRETVLT 180
LGVEAAKRAGVTITGAFDDACASYFGGLCITDNYEMEILVKREINPETVVLLIPRETVLT
Sbjct: 121 LGVEAAKRAGVTITGAFDDACASYFGGLCITDNYEMEILVKREINPETVVLLIPRETVLT 180
Query: 181 ESLKGVDFSKISPFIGEALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALKLGAFVG 240
ESLKGVDFSKISPFIGEALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALKLGAFVG
Sbjct: 181 ESLKGVDFSKISPFIGEALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALKLGAFVG 240
Query: 241 LCGKGPAFFAIADEPEEIIEAWSSFGDVIATSLR 274
LCGKGPAFFAIADEPEEIIEAWSSFGDVIATSLR
Sbjct: 241 LCGKGPAFFAIADEPEEIIEAWSSFGDVIATSLR 274
>pir||E69207 conserved hypothetical protein MTH805 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621895|gb|AAB85305.1| (AE000858) conserved protein
(homoserine kinase related) [Methanobacterium
thermoautotrophicum]
Length = 289
Score = 161 bits (402), Expect = 1e-38
Identities = 98/277 (35%), Positives = 151/277 (54%), Gaps = 14/277 (5%)
Query: 6 RASSAITIVNAFATGKGAAIGIELWTEARVRVTGDGEVRGKIVVKGEEFKDYRLVNSVIS 65
R+ + T++NA ATG+G+A GI L EA + G + E D L+
Sbjct: 9 RSPGSATVINAIATGRGSAFGIGLRVEAEAELIDSG-----VECISREGADTSLMELCTR 63
Query: 66 VLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRLN-----IDDLSIVK 120
++ E G GVR SD+PV GL SSSAA+N+ A+ L ++D ++
Sbjct: 64 MVIEHYGVDAGVRVVTSSDLPVASGLSSSSAASNATVMAVSSLLSDEFGLQPMEDFEMLN 123
Query: 121 LGVEAAKRAGVTITGAFDDACASYFGGLCITDNYEMEILVKREINPETVVLLIPRETVLT 180
+ V+A+ +AGV++TGA+DDA AS++GGL +TDN E I+++ + + V++ +P LT
Sbjct: 124 MAVDASLQAGVSVTGAYDDASASFYGGLTVTDNMERRIILREPMENQKVLIYMPDRKSLT 183
Query: 181 ESLKGVDFSKISPFIGEALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALKLGAF-V 239
++P++ A R + G AL +NG+LY LG+D +AL+ GA
Sbjct: 184 AQSDVPRMKLLAPWVDMAFREVLDGRVHSALTLNGILYCASLGFDPGIALDALEAGALAA 243
Query: 240 GLCGKGPAFFAIADEPEE--IIEAWSSF-GDVIATSL 273
GL G GP+F A+ E E II+AW + GDV+ TS+
Sbjct: 244 GLSGTGPSFVALTHEDSEADIIDAWENLEGDVLVTSV 280
>pir||G64479 hypothetical protein MJ1440 - Methanococcus jannaschii
>gi|1500322|gb|AAB99451.1| (U67585) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 282
Score = 152 bits (381), Expect = 3e-36
Identities = 101/280 (36%), Positives = 162/280 (57%), Gaps = 17/280 (6%)
Query: 1 MRGSGRASSAITIVNAFATGKGAAIGIELWTEARVRVTGDGE--VRGKIVVKGEEFKDYR 58
M G A ++ TI+NA ATGKG+A G++L A+V++ DG+ + GK V+ K
Sbjct: 1 MEGKAYALASGTIINAIATGKGSAFGLDLKVYAKVKLIDDGKNKIEGK-VLDNPNIKPNL 59
Query: 59 LVNSVISVLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRLNIDDLSI 118
+V V + L + G + E ++IP+ GL SSSA +N++ A +AL IDD I
Sbjct: 60 IVRCVKNTL-DYFGLNYSAYVETKTEIPIKSGLSSSSATSNAVVLATFDALGEKIDDELI 118
Query: 119 VKLGVEAAKRAGVTITGAFDDACASYFGGLCITDNYEMEILVKREINPE-TVVLLIPRET 177
+ LG++++ +T+TGA+DDA ASY+GG+ ITDN E +IL + ++ + V++LIP
Sbjct: 119 LNLGIKSSFDEKLTVTGAYDDATASYYGGITITDNIERKILKRDKMRDDLNVLILIPNLE 178
Query: 178 VLTESLKGVDFSK---ISPFIGEALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALK 234
K VD ++ I ++ A AI+G + KAL +NG+LY++ L + +AL
Sbjct: 179 ------KNVDVNRMKLIKDYVEIAFNEAINGNYFKALFLNGILYASALNFPTNIAIDALD 232
Query: 235 LGAF-VGLCGKGPAFFAIADEP--EEIIEAWSSFGDVIAT 271
GA GL G GP++ A+ ++ E++ E + +G VI T
Sbjct: 233 AGAITAGLSGTGPSYIAMVEDENVEKVKEKLNRYGKVILT 272
>gb|AAG19605.1| (AE005050) Vng1245c [Halobacterium sp. NRC-1]
Length = 284
Score = 150 bits (374), Expect = 2e-35
Identities = 98/267 (36%), Positives = 143/267 (52%), Gaps = 8/267 (2%)
Query: 1 MRGSGRASSAITIVNAFATGKGAAIGIELWTEARVRVT-GDGEVRGKIVVKGEEFKDYRL 59
M G A +A T++NA ATG GAA +++ TEA V VT + V G+I G D L
Sbjct: 1 MDGRAVAPAAGTVLNALATGVGAAFALDIDTEASVSVTPSESGVSGEIA--GHPEADTAL 58
Query: 60 VNSVISVLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRL--NIDDLS 117
V +S + + G+ G S++P+ GLKSSSAAAN+ A ++AL + +D +
Sbjct: 59 VERCVSRVIDRYGDGQGGHVRTESEVPLAAGLKSSSAAANATVLATLDALGVADEVDRVD 118
Query: 118 IVKLGVEAAKRAGVTITGAFDDACASYFGGLCITDNYEMEILVKREINPETVVLLIPRET 177
+LGV+AA+ AGVT+TGAFDDA AS GG+ +TDN E ++L + + V P E
Sbjct: 119 AARLGVQAARDAGVTVTGAFDDAAASMLGGVAMTDNREDDLLFRDAVEWHAAV-WTPPER 177
Query: 178 VLTESLKGVDFSKISPFIGEALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALKLGA 237
+ ++S LA +G++ A+ +NGL + L + AP AL A
Sbjct: 178 AYSADADVARCERVSGLAEHVAALAAAGDYGTAMTVNGLAFCAALDFPTAPAVTALPHAA 237
Query: 238 FVGLCGKGPAFFAIADEP--EEIIEAW 262
V L G GP++ A+ DE EE+ W
Sbjct: 238 GVSLSGTGPSYVAVGDEDGIEEVSTRW 264
>pir||D72642 hypothetical protein APE0572 - Aeropyrum pernix (strain K1)
>gi|5104225|dbj|BAA79540.1| (AP000060) 280aa long
hypothetical protein [Aeropyrum pernix]
Length = 280
Score = 114 bits (282), Expect = 1e-24
Identities = 84/269 (31%), Positives = 126/269 (46%), Gaps = 13/269 (4%)
Query: 6 RASSAITIVNAFATGK-GAAIGIELWTEARVRVTGDGEVRG-----KIVVKGEEFKDYRL 59
RAS +TIVNA G+ G A G+ LW E+RVR E RG + +GE R+
Sbjct: 5 RASGGLTIVNAIGHGRLGGAAGLGLWVESRVR-----EARGLWAGVSLTPRGERRLPPRV 59
Query: 60 VNSVISVLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRLNIDDLSIV 119
+ + + + G+ E+H+ P G GLK S+A SL +A++ +
Sbjct: 60 LEAAATAACSLGACVEGLEAEVHTGFPPGVGLKGSAALLASLVEAVLRLKGVRAPPWRAA 119
Query: 120 KLGVEAAKRAGVTITGAFDDACASYFGGLCITDNYEMEI--LVKREINPETVVLLIPRET 177
++ AG+++TGA DD AS ITDN M I L+ R+ T V+ +P
Sbjct: 120 LAAARVSRGAGLSVTGALDDHAASLLEAPVITDNRGMAILRLLPRDGCRLTAVIGVPGVE 179
Query: 178 VLTESLKGVDFSKISPFIGEALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALKLGA 237
E+L F + S A RL ++GEW A+ ++G+ + LG + R A
Sbjct: 180 NPVENLDPSPFRRHSRLYDAAARLGLAGEWLPAMAVSGVAGALALGVEGLASRLYEAGAA 239
Query: 238 FVGLCGKGPAFFAIADEPEEIIEAWSSFG 266
G+ GKGPA FA+ + P E + G
Sbjct: 240 AAGVTGKGPAVFALTERPRGAAEVLETAG 268
>emb|CAC11428.1| (AL445063) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 268
Score = 112 bits (278), Expect = 4e-24
Identities = 84/269 (31%), Positives = 126/269 (46%), Gaps = 20/269 (7%)
Query: 6 RASSAITIVNAFATGKGAAIGIELWTEARVRVTGDGEVRGKIVVKGEEFKDYRLVNSVIS 65
R ++I++AF G G A I++ VR G + + +D R S+ +
Sbjct: 7 RTHGGVSIISAFIDGMGGAFSIDVPMTVTVR-------EGTCSEEKKISEDIRRYLSIAT 59
Query: 66 VLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRLNIDDLSIVKLGVEA 125
R F + S IP G GLKSSSA +L KA+ ++I D+ I+ +
Sbjct: 60 CFR----------FTVDSRIPSGYGLKSSSAYILALAKAMAVYSGIDISDMEIMTASADI 109
Query: 126 AKRAGVTITGAFDDACASYFGGLCITDNYEMEILVKREINPETVVLLIPRETVLTESLKG 185
+K +G+++TGA DD C + +GG C+TDN +M+IL +R PE VL+ +
Sbjct: 110 SKNSGLSMTGALDDLCQAMYGGYCLTDNRKMKIL-RRGRLPEMPVLVCADGDKRSSGKVS 168
Query: 186 VDFSKISPFIGEALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALKLGA-FVGLCGK 244
++ + I LA G A V NGL+Y + G DL + LK GA + GK
Sbjct: 169 IE-GHFTNAIRRVEDLAFKGRIFDAAVANGLIYGSIFGMDLRLIGSMLKAGALYSSQSGK 227
Query: 245 GPAFFAIADEPEEIIEAWSSFGDVIATSL 273
GPA F I + + A S G I T +
Sbjct: 228 GPAIFGIFADRRSAMNARSDIGFGIVTKI 256
>gi|11498131 conserved hypothetical protein [Archaeoglobus fulgidus]
>gi|7447992|pir||H69314 conserved hypothetical protein
AF0520 - Archaeoglobus fulgidus
>gi|2650100|gb|AAB90713.1| (AE001068) conserved
hypothetical protein [Archaeoglobus fulgidus]
Length = 280
Score = 111 bits (275), Expect = 9e-24
Identities = 86/271 (31%), Positives = 137/271 (49%), Gaps = 28/271 (10%)
Query: 6 RASSAITIVNAFATGKGAAIGIELWTEARVRVTGDGEVRGKIVVKGEEFKDY---RLVNS 62
+A +A T++NA TG G+A GIE+ T ++R + + K+ V G E + R++NS
Sbjct: 5 KAYAAGTVLNALPTGIGSAFGIEMHTIVKLRPSDEL----KVFVNGVERRSIVAERILNS 60
Query: 63 VISVLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRLNIDDLSIVKLG 122
+ +VT E + S+IP G GL SSSA N+L A+ + ++ I++
Sbjct: 61 M-----DVTAEVI-----VESEIPGGSGLGSSSAFVNALICAVKKMKGEELNAFEILRSN 110
Query: 123 VEAAKRAGVTITGAFDDACASYFGGLCITDNYEMEILVKREINPETVVLLIPRETVLTES 182
+ AG++ TGAFDDA AS GG ++DN +M ++ E + V LIP+ S
Sbjct: 111 ARFSLEAGISYTGAFDDASASMLGGFVVSDNRKMRLIRTDEFEGYSAV-LIPK-----FS 164
Query: 183 LKGVDFSKISPFIGE---ALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALKLGAFV 239
VD+ ++ E A+ A+ GE+ KA+ +N LGY L + + G
Sbjct: 165 RGKVDWRRLRERASEVEGAVEAAMRGEYCKAMKLNTEYICKMLGYPLEIAEKGWEKGICC 224
Query: 240 GLCGKGPAF--FAIADEPEEIIEAWSSFGDV 268
G+ G GP++ F +E E + E W +G V
Sbjct: 225 GISGNGPSYVAFGSKNEMEALAETWGEYGRV 255
>gb|AAK40645.1| Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 275
Score = 111 bits (274), Expect = 1e-23
Identities = 84/267 (31%), Positives = 141/267 (52%), Gaps = 19/267 (7%)
Query: 6 RASSAITIVNAFATGKGAAIGIELWTEARVRVTGDGEVRGKIVVKGEEFKDYRLVNSVIS 65
+A ++IVNA + G+++ I L + +R GK V E L+ ++++
Sbjct: 9 QAYGGVSIVNALPSWYGSSMAINLKVKVEIR-------EGKRVYSQES----ELIKTILN 57
Query: 66 VLREVTGEPFGVRFEIHSDIPVGKGLKSSSAAANSLTKALVEALRLNIDDLSIVKLGVEA 125
+E P + +I S++P GLKSSSA + +L + A + ++ +++ L
Sbjct: 58 YFKEKYSIP-DIEVDIESELPQKSGLKSSSAVSVALIAEI--AKQYDLRNINPPILSAIL 114
Query: 126 AKRAGVTITGAFDDACASYFGGLCITDNYEMEILVKREINPETVVLLIPRETVLTESLKG 185
+ +AGV+ TGA DDA ASY GG+ T N +M +VK E + + +LI + + +
Sbjct: 115 SLKAGVSYTGALDDAVASYCGGIAFTYN-KMFRIVKLENLEDNLSILILAKGGRQKPVNL 173
Query: 186 VDFSKISPFIGEALRLAISGEWKKALVINGLLYSTFLGYDLAPMREALKLGAF-VGLCGK 244
+ K S E ++A+ ++ A+ +NG+L + LGY L P+ ALK GA G+ G
Sbjct: 174 NELRKYSHVFEEIFKIALK-DYLTAMKMNGILIANILGYSLEPIEIALKKGALAAGISGN 232
Query: 245 GPAFFAIADEPEE--IIEAWSSFGDVI 269
GP++FA++ EE I E+ FGDVI
Sbjct: 233 GPSYFAVSKNGEEGPIYESLKKFGDVI 259
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.138 0.390
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95430102
Number of Sequences: 2977
Number of extensions: 3818264
Number of successful extensions: 8405
Number of sequences better than 1.0e-10: 8
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 8382
Number of HSP's gapped (non-prelim): 8
length of query: 274
length of database: 189,106,746
effective HSP length: 57
effective length of query: 217
effective length of database: 154,992,987
effective search space: 33633478179
effective search space used: 33633478179
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 164 (68.3 bits)