BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0328 (PAB0328) DE:OXIDOREDUCTASE
(235 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75166 oxidoreductase PAB0328 - Pyrococcus abyssi (strain O... 469 e-131
gb|AAK41293.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-... 112 4e-24
sp|P54554|YQJQ_BACSU HYPOTHETICAL OXIDOREDUCTASE IN ANSR-BMRU IN... 101 1e-20
pir||B83161 probable short-chain dehydrogenase PA3883 [imported]... 95 8e-19
dbj|BAB05225.1| (AP001512) oxidoreductase [Bacillus halodurans] 94 1e-18
sp|P77388|YBBO_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN USHA-TESA IN... 88 1e-16
pir||H83564 probable short-chain dehydrogenase PA0658 [imported]... 86 3e-16
gi|6322067 1-Acyl dihydroxyacetone phosphate reductase; Ayr1p [S... 85 7e-16
sp|P55434|Y4EK_RHISN PUTATIVE SHORT-CHAIN TYPE DEHYDROGENASE/RED... 85 9e-16
pir||A75482 oxidoreductase, short-chain dehydrogenase/reductase ... 84 2e-15
gb|AAF48896.1| (AE003510) CG7322 gene product [Drosophila melano... 83 2e-15
gb|AAB08021.1| (U43704) aklaviketone reductase [Streptomyces sp.... 83 2e-15
sp|P37694|HETN_ANASP KETOACYL REDUCTASE HETN >gi|1075641|pir||C5... 82 5e-15
emb|CAB94622.1| (AL359214) putative oxidoreductase [Streptomyces... 82 8e-15
emb|CAC01636.1| (AL391072) putative ketoreductase [Streptomyces ... 81 1e-14
pir||T41028 short chain dehydrogenase - fission yeast (Schizosa... 81 1e-14
gi|6671688 carbonyl reductase 2 [Mus musculus] >gi|113986|sp|P08... 81 1e-14
emb|CAC11583.1| (AL445064) 3-oxoacyl-[acyl-carrier-protein] redu... 81 1e-14
dbj|BAB11656.1| (AB013395) contains similarity to dehydrogenase~... 80 2e-14
gb|AAA65202.1| (L35560) daunorubicin-doxorubicin polyketide synt... 80 3e-14
gb|AAF01806.1|AF187532_2 (AF187532) C-7 ketoreductase [Streptomy... 80 3e-14
pir||G83473 probable short-chain dehydrogenase PA1379 [imported]... 80 3e-14
gb|AAD44003.1| (U59485) AtsC [Agrobacterium tumefaciens] 79 5e-14
gi|7705905 retinal short-chain dehydrogenase/reductase retSDR2 [... 79 5e-14
pir||F82378 oxidoreductase, short-chain dehydrogenase/reductase ... 79 5e-14
gb|AAF73457.1|AF264025_8 (AF264025) putative aklaviketone reduct... 78 9e-14
emb|CAB65876.1| (AL109630) /match=(desc:""3-OXOACYL-[ACYL-CARRIE... 78 1e-13
pir||D70948 hypothetical protein Rv3174 - Mycobacterium tubercul... 77 2e-13
pir||S51948 hypothetical protein - Agrobacterium tumefaciens >gi... 77 2e-13
emb|CAB51140.1| (Y18818) oxidoreductase of short-chain [Streptom... 76 3e-13
pir||T32196 hypothetical protein T01G6.1 - Caenorhabditis elegan... 76 3e-13
pir||T45275 oxidoreductase of short-chain [imported] - Streptomy... 76 3e-13
sp|Q29529|CBR2_PIG LUNG CARBONYL REDUCTASE [NADPH] (NADPH-DEPEND... 75 6e-13
gb|AAB82041.1| (U59236) unknown [Synechococcus PCC7942] 75 6e-13
emb|CAB51900.1| (Y19033) 1,3,6,8-tetrahydroxynaphthalene reducta... 75 6e-13
pir||D75522 oxidoreductase, short-chain dehydrogenase/reductase ... 75 6e-13
pir||C75365 daunorubicin C-13 ketoreductase - Deinococcus radiod... 75 6e-13
pir||S56475 hypothetical protein f261a - Escherichia coli >gi|53... 75 8e-13
sp|P39333|YJGI_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN PYRL-ARGI IN... 75 8e-13
gb|AAF45573.1| (AE003419) EG:BACR7A4.14 gene product [Drosophila... 75 8e-13
gi|6755380 retinal short-chain dehydrogenase/reductase 1 [Mus mu... 75 1e-12
gi|7705925 carbonyl reductase [Homo sapiens] >gi|6523809|gb|AAF1... 75 1e-12
pir||A82604 oxidoreductase XF2082 [imported] - Xylella fastidios... 75 1e-12
dbj|BAB07807.1| (AB032242) serine dehydrogenase [Agrobacterium t... 75 1e-12
gb|AAD03695.1| (AF090422) surface sperm protein P26h [Mesocricet... 75 1e-12
gb|AAC63265.1| (AF061743) retinal short-chain dehydrogenase/redu... 75 1e-12
pir||C83416 probable short-chain dehydrogenase PA1827 [imported]... 75 1e-12
pir||E83135 probable dehydrogenase PA4079 [imported] - Pseudomon... 74 1e-12
sp|P14802|YOXD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN RTP-PELB INT... 74 2e-12
gi|6320089 Ydl114wp [Saccharomyces cerevisiae] >gi|2131337|pir||... 74 2e-12
sp|O57314|DHBX_ANAPL PUTATIVE STEROID DEHYDROGENASE SPM2 >gi|266... 74 2e-12
gb|AAC63264.1| (AF061742) retinal short-chain dehydrogenase/redu... 74 2e-12
pir||T35808 probable oxidoreductase - Streptomyces coelicolor >g... 74 2e-12
pir||D75336 oxidoreductase, short-chain dehydrogenase/reductase ... 74 2e-12
pir||H81140 oxidoreductase, short-chain dehydrogenase/reductase ... 74 2e-12
pir||D81878 probable oxidoreductase NMA1120 [imported] - Neisser... 74 2e-12
pir||F83479 probable short-chain dehydrogenase PA1330 [imported]... 74 2e-12
pir||F83229 probable short chain dehydrogenase PA3330 [imported]... 74 2e-12
gi|4759084 short-chain dehydrogenase/reductase 1 [Homo sapiens] ... 73 3e-12
gb|AAF53953.1| (AE003669) CG9265 gene product [Drosophila melano... 73 4e-12
pir||T49258 dehydrogenase-like protein - Arabidopsis thaliana >g... 73 4e-12
pir||G82239 oxidoreductase, short-chain dehydrogenase/reductase ... 73 4e-12
pir||H83046 probable short-chain dehydrogenase PA4786 [imported]... 73 4e-12
gb|AAD00504.1| (U81186) smooth muscle-specific 17beta-hydroxyste... 72 5e-12
pir||H75014 3-oxoacyl-[acyl-carrier-protein] reductase PAB1085 -... 71 9e-12
pir||T37016 probable oxidoreductase - Streptomyces coelicolor >g... 71 9e-12
emb|CAB58279.1| (AL121849) putative oxidoreductase [Streptomyces... 71 9e-12
sp|O85141|FABG_SALTY 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 71 1e-11
pir||T36060 probable oxidoreductase - Streptomyces coelicolor >g... 71 1e-11
gb|AAC95219.1| (AC004561) putative tropinone reductase [Arabidop... 71 1e-11
pir||F81902 probable oxidoreductase NMA1336 [imported] - Neisser... 71 1e-11
pir||F70547 hypothetical protein Rv0547c - Mycobacterium tubercu... 71 2e-11
pir||T35242 probable oxidoreductase - Streptomyces coelicolor >g... 71 2e-11
pir||T47668 oxidoreductase-like protein - Arabidopsis thaliana ... 71 2e-11
dbj|BAB04657.1| (AP001510) glucose 1-dehydrogenase [Bacillus hal... 71 2e-11
emb|CAC13079.1| (AL445503) putative oxidoreductase [Streptomyces... 71 2e-11
gb|AAA50845.1| (J05282) insect-type dehydrogenase [Burkholderia ... 70 2e-11
sp|P50199|GNO_GLUOX GLUCONATE 5-DEHYDROGENASE (5-KETO-D-GLUCONAT... 70 2e-11
emb|CAB69764.1| (AL137187) putative dehydrogenase/reductase [Str... 70 2e-11
pir||F81117 oxidoreductase, short chain dehydrogenase/reductase ... 70 2e-11
gb|AAF50980.1| (AE003575) CG15629 gene product [Drosophila melan... 70 2e-11
gi|7657478 photoreceptor outer segment all-trans retinol dehydro... 70 2e-11
gi|11424840 photoreceptor outer segment all-trans retinol dehydr... 70 2e-11
gi|6322227 Yir036cp [Saccharomyces cerevisiae] >gi|731923|sp|P40... 70 3e-11
pir||B69802 glucose 1-dehydrogenase homolog yfhR - Bacillus subt... 70 3e-11
gi|9789991 cDNA sequence AF064635; putative steroid dehydrogenas... 70 3e-11
emb|CAA07768.1| (AJ007932) ketoreductase [Streptomyces argillaceus] 70 3e-11
pir||T29125 ketoacyl reductase homolog - Streptomyces coelicolor... 70 3e-11
gb|AAD13552.1| (AF080235) reductase homolog [Streptomyces cyanog... 70 3e-11
pir||D83042 probable short-chain dehydrogenase PA4832 [imported]... 70 3e-11
sp|O05730|VDLC_HELPY PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/RED... 69 3e-11
emb|CAB61164.1| (AL132973) short chain oxidoreductase [Streptomy... 69 3e-11
gi|10955028 mas1' [Agrobacterium tumefaciens] >gi|1708926|sp|P50... 69 5e-11
sp|P43713|FABG_HAEIN 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 69 5e-11
pir||F69868 glucose 1-dehydrogenase homolog ykvO - Bacillus subt... 69 5e-11
gb|AAF19703.1|AC008047_10 (AC008047) F2K11.24 [Arabidopsis thali... 69 6e-11
pir||E82748 tropinone reductase XF0913 [imported] - Xylella fast... 69 6e-11
gb|AAC25556.1| (AF013169) short chain alcohol dehydrogenase [Pyr... 68 8e-11
gb|AAD37453.1| (AF074603) putative ketoacyl reductase; NonE [Str... 68 8e-11
gb|AAF86624.1| (U87786) clavaldehyde dehydrogenase [Streptomyces... 68 8e-11
sp|P57432|FABG_BUCAI 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE ... 68 8e-11
>pir||D75166 oxidoreductase PAB0328 - Pyrococcus abyssi (strain Orsay)
>gi|5457921|emb|CAB49411.1| (AJ248284) OXIDOREDUCTASE
[Pyrococcus abyssi]
Length = 235
Score = 469 bits (1193), Expect = e-131
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKYIVVDLSTYEG 60
MGFLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKYIVVDLSTYEG
Sbjct: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKYIVVDLSTYEG 60
Query: 61 ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEG 120
ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEG
Sbjct: 61 ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEG 120
Query: 121 GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWK 180
GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWK
Sbjct: 121 GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWK 180
Query: 181 GAKLRGALSPEYVARKIVNAIESDKRELFIPWYLKLAKFFEIKYRFSFEKEFKPQ 235
GAKLRGALSPEYVARKIVNAIESDKRELFIPWYLKLAKFFEIKYRFSFEKEFKPQ
Sbjct: 181 GAKLRGALSPEYVARKIVNAIESDKRELFIPWYLKLAKFFEIKYRFSFEKEFKPQ 235
>gb|AAK41293.1| 3-oxoacyl-(acyl carrier protein) reductase (fabG-2) [Sulfolobus
solfataricus]
Length = 247
Score = 112 bits (277), Expect = 4e-24
Identities = 75/223 (33%), Positives = 120/223 (53%), Gaps = 13/223 (5%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKYIVVDLST-YEGISKVRESL 68
++TGAS GIG+ + K L Y V+ + R++ + ++ V D ST + +++V E
Sbjct: 6 IVTGASKGIGRAVVKLLKENNYTVVSISRSKSDIGDVIYDADVSDRSTVFRIVNEVLEKF 65
Query: 69 KGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFI--PEGGKVVFI 126
G+IDVL+NNAGFG+ LE E E M + N +AP+ K +L + G VV I
Sbjct: 66 -GKIDVLVNNAGFGVYGSFLETDLNEEEYMIRTNLLAPLYFMKAVLPHMVSRRKGSVVNI 124
Query: 127 ISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWKGAKLRG 186
+S A++V T L Y A+K L + L E+++ ++V VYP V T+F +
Sbjct: 125 VSEAAYVSTPKLLVYSATKAGLASLTNGLWAEMRKYNVRVSGVYPGPVRTNFTSHPSFKK 184
Query: 187 ---------ALSPEYVARKIVNAIESDKRELFIPWYLKLAKFF 220
++ PE VA+ ++ AI + KRE+++P LKL +F
Sbjct: 185 NNGDPFANYSVEPEAVAKAVLKAIRTGKREIYVPSRLKLDPYF 227
>sp|P54554|YQJQ_BACSU HYPOTHETICAL OXIDOREDUCTASE IN ANSR-BMRU INTERGENIC REGION
>gi|7431003|pir||A69965 ketoacyl reductase homolog yqjQ
- Bacillus subtilis >gi|1303968|dbj|BAA12623.1| (D84432)
YqjQ [Bacillus subtilis] >gi|2634813|emb|CAB14310.1|
(Z99116) similar to ketoacyl reductase [Bacillus
subtilis]
Length = 259
Score = 101 bits (248), Expect = 1e-20
Identities = 76/225 (33%), Positives = 114/225 (49%), Gaps = 22/225 (9%)
Query: 8 RVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKY----------IVVDLST 57
R+ +TGASGG+G+ +A G V+ R E L E+ K +D+
Sbjct: 8 RIWITGASGGLGERIAYLCAAEGAHVLLSARREDRLIEIKRKITEEWSGQCEIFPLDVGR 67
Query: 58 YEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFI 117
E I++VR+ + G IDVLINNAGFG+ + +L+ + ++++ MF VN + TK +L +
Sbjct: 68 LEDIARVRDQI-GSIDVLINNAGFGIFETVLDSTLDDMKAMFDVNVFGLIACTKAVLPQM 126
Query: 118 PE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVA 175
E G ++ I S A + T Y A+K A+ + L EL GI V V P +
Sbjct: 127 LEQKKGHIINIASQAGKIATPKSSLYSATKHAVLGYSNALRMELSGTGIYVTTVNPGPIQ 186
Query: 176 TDFW----KGAKL-----RGALSPEYVARKIVNAIESDKRELFIP 211
TDF+ KG R L P+ VA +I AI + KRE+ +P
Sbjct: 187 TDFFSIADKGGDYAKNVGRWMLDPDDVAAQITAAIFTKKREINLP 231
>pir||B83161 probable short-chain dehydrogenase PA3883 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950063|gb|AAG07270.1|AE004805_8 (AE004805) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 276
Score = 94.8 bits (232), Expect = 8e-19
Identities = 61/179 (34%), Positives = 93/179 (51%), Gaps = 7/179 (3%)
Query: 11 LTGASGGIGQELAKELIRRGYEVIGVGRNE---KALKELGIKYIVVDLSTYEGISKVRES 67
+TG S GIG+ LA R GY V R E +AL E G + + +D++ ++++ E
Sbjct: 8 VTGCSSGIGRALADAFQRAGYRVWASARKEDDVRALAEAGFQAVQLDVNDAAALARLAEE 67
Query: 68 LKGE---IDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEGGKVV 124
L E +DVL+NNAG+G + PLL+ E + F+ N A V +T+ L + +V
Sbjct: 68 LGVEAAGLDVLVNNAGYGAMGPLLDGGVEAMRRQFETNVFAVVGVTRALFPLLRRKSGLV 127
Query: 125 FIISGASHVYTLDLPG-YGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWKGA 182
+ S V G Y ASK A+H ++ L EL G++VL V P +A++F A
Sbjct: 128 VNVGSVSGVLVTPFAGAYCASKAAVHALSDALRLELAPFGVEVLEVQPGAIASNFGASA 186
>dbj|BAB05225.1| (AP001512) oxidoreductase [Bacillus halodurans]
Length = 259
Score = 94.0 bits (230), Expect = 1e-18
Identities = 73/231 (31%), Positives = 112/231 (47%), Gaps = 23/231 (9%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL--------GIKYIV-VDLSTYE 59
+ +TGAS G+G++LA + + R+++ L+ + G +I VDL+ +
Sbjct: 6 IFITGASSGLGRQLAIDFSWEETVLCLFARSQERLENVQRIVVENGGEAHIYPVDLADPQ 65
Query: 60 GISKVRE---SLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
I + S G +DVLINNAG+G+ +P + +E E MF+VN + T +L
Sbjct: 66 SIDRSFAEAISAVGVVDVLINNAGYGVFEPFCDSQMDENERMFRVNVFGLMRATAAVLPT 125
Query: 117 IPE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQV 174
+ E G ++ I S A + T Y A+K A+ L ELK GI V V P +
Sbjct: 126 MREQGSGHIINIASQAGKIATAKSAIYSATKHAVLGFTNSLRMELKGTGIHVSAVNPGPI 185
Query: 175 ATDFWKGAKLRGA---------LSPEYVARKIVNAIESDKRELFIPWYLKL 216
T F+ A GA L PE V+ KIV + KREL +PW++ +
Sbjct: 186 QTPFFDQADKEGAYTSKVQRIMLDPEDVSEKIVQLTKKPKRELNLPWWMNI 236
>sp|P77388|YBBO_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN USHA-TESA INTERGENIC REGION
>gi|7449074|pir||D64780 probable retinol dehydrogenase
(EC 1.1.1.-) - Escherichia coli
>gi|1773175|gb|AAB40247.1| (U82664) similar to human
protein that oxidizes 11-cis retinol into 11-cis
retinaldehyde [Escherichia coli]
>gi|1786701|gb|AAC73595.1| (AE000155) putative
oxidoreductase [Escherichia coli K12]
Length = 269
Score = 87.8 bits (214), Expect = 1e-16
Identities = 70/226 (30%), Positives = 102/226 (44%), Gaps = 23/226 (10%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNE---KALKELGIKYIVVDLSTYEGISKVR 65
VL+TG S GIG E A EL R+G+ V+ R + + +G +++DL + E + +
Sbjct: 18 VLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAA 77
Query: 66 ESLKGEIDV----LINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD-FIPEG 120
+ + D + NNAGFG+ PL S ++E F N LT LL +P G
Sbjct: 78 DEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHG 137
Query: 121 -GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFW 179
G++V S + T Y ASK AL + L EL+ GIKV + P + T F
Sbjct: 138 EGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFT 197
Query: 180 --------------KGAKLRGALSPEYVARKIVNAIESDKRELFIP 211
G R L PE V K+ +A S+K ++ P
Sbjct: 198 DNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKMRYP 243
>pir||H83564 probable short-chain dehydrogenase PA0658 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9946535|gb|AAG04047.1|AE004500_13 (AE004500)
probable short-chain dehydrogenase [Pseudomonas
aeruginosa]
Length = 266
Score = 86.2 bits (210), Expect = 3e-16
Identities = 69/225 (30%), Positives = 110/225 (48%), Gaps = 24/225 (10%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG----------IKYIVVDLST-- 57
L+TGAS GIG LA+ L RRG +I V R AL+ + + + DLS
Sbjct: 6 LITGASSGIGLALAEALARRGRALILVARQRDALESIAYELAQRFGVEVLFRTCDLSEPL 65
Query: 58 -YEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
G+ E + +ID+L+NNAG G P ++ W + + ++N +A L L
Sbjct: 66 QLSGLLHELEQGERQIDLLVNNAGIGTSGPFIDQEWAREQELIELNILALARLCHSLGAR 125
Query: 117 IPE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQV 174
+ GG+++ I S A+ + Y ASK + + ++ L EELKERG+KV + P
Sbjct: 126 MAAQGGGQILNIASVAAFQPGAWMSNYYASKAYVLHFSEGLREELKERGVKVSVLCPGPT 185
Query: 175 ATDFWKGAKLRGA--------LSPEYVARKIVNAIESDKRELFIP 211
T F++ A +R ++PE VA + ++ + R L +P
Sbjct: 186 RTAFFREAGMRLGRLDRSKLMMTPEEVALLALRGLDKN-RALIVP 229
>gi|6322067 1-Acyl dihydroxyacetone phosphate reductase; Ayr1p [Saccharomyces
cerevisiae] >gi|731868|sp|P40471|YIM4_YEAST HYPOTHETICAL
OXIDOREDUCTASE IN KGD1-SIM1 INTERGENIC REGION
>gi|1077756|pir||S49885 probable membrane protein
YIL124w - yeast (Saccharomyces cerevisiae)
>gi|599993|emb|CAA86868.1| (Z46833) unknown
[Saccharomyces cerevisiae]
Length = 297
Score = 85.0 bits (207), Expect = 7e-16
Identities = 63/181 (34%), Positives = 91/181 (49%), Gaps = 13/181 (7%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKYIVVDLSTYE-GISKVRESL 68
++TGASGGIG E+ KEL R GY V R + + +L I++ + Y+ ISK E +
Sbjct: 13 VVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQLAIQFGNDSIKPYKLDISKPEEIV 72
Query: 69 -----------KGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF- 116
G++D+L NNAG P L+ + +E FKVN + + +EL +F
Sbjct: 73 TFSGFLRANLPDGKLDLLYNNAGQSCTFPALDATDAAVEQCFKVNVFGHINMCRELSEFL 132
Query: 117 IPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
I G +VF S A V Y ASK A+H A+ L E+K ++V+ VAT
Sbjct: 133 IKAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNVRVINAITGGVAT 192
Query: 177 D 177
D
Sbjct: 193 D 193
>sp|P55434|Y4EK_RHISN PUTATIVE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE Y4EK
>gi|2182379|gb|AAB91654.1| (AE000071) Y4eK [Rhizobium
sp. NGR234]
Length = 248
Score = 84.7 bits (206), Expect = 9e-16
Identities = 71/216 (32%), Positives = 112/216 (50%), Gaps = 22/216 (10%)
Query: 6 YMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL----GIKYIVVDLSTYEGI 61
Y L+TGAS GIG+ +A EL G V+ +GR+ AL EL GI +V DLS +
Sbjct: 7 YEVALVTGASSGIGKAIALELASAGLRVLALGRDRAALDELHSTAGIVPVVFDLS---DV 63
Query: 62 SKVRESLKGE-IDVLINNAGFGLVK-PLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE 119
S+V + GE IDVL+NNAG L++ S ++++ M +N + LT+ +L + E
Sbjct: 64 SEVYGKIAGEKIDVLVNNAGLLTASASLVDLSEDDIDAMIDINIRSVFKLTRHVLKQMIE 123
Query: 120 --GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATD 177
G + F S + YGA+K A+ + L +L I+V ++P +V T+
Sbjct: 124 RRRGHIFFTGSSGGLAPHPNSSVYGATKAAVSLFSSALRCDLIGLPIRVTELFPGRVETN 183
Query: 178 FWK------GAKLR-----GALSPEYVARKIVNAIE 202
++ GAK + A+ PE++AR + A+E
Sbjct: 184 LYRTALGKEGAKKKLYDDNEAIQPEHMARLLRTALE 219
>pir||A75482 oxidoreductase, short-chain dehydrogenase/reductase family -
Deinococcus radiodurans (strain R1)
>gi|6458439|gb|AAF10309.1|AE001929_2 (AE001929)
oxidoreductase, short-chain dehydrogenase/reductase
family [Deinococcus radiodurans]
Length = 251
Score = 83.9 bits (204), Expect = 2e-15
Identities = 59/193 (30%), Positives = 101/193 (51%), Gaps = 11/193 (5%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKYIVVDLSTYEGISKVRESL 68
V++TGA+ GIG+ +A+ + RG+ V+GV + + G + + D++T G +++ ++
Sbjct: 10 VVVTGAARGIGRAIAELYVERGHPVLGVDLSLPPVLR-GQRRVKADIATAAGRARILKAA 68
Query: 69 K--GEIDVLINNAGF----GLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEGGK 122
+ GE+ VL+NNA + G V + E W VN AP++LT+EL++ +P G
Sbjct: 69 REHGEVSVLVNNAAYQDAHGSVLEVSERGWART---LNVNLTAPLLLTRELIELLPSGSA 125
Query: 123 VVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWKGA 182
VV + S Y ASK L + + + +L RG++V V P +AT+ A
Sbjct: 126 VVNVASVQGLFAEQGNAAYNASKGGLVNLTRAMCLDLAPRGLRVNAVAPGAIATEAVLQA 185
Query: 183 KLRGALSPEYVAR 195
+ G+ PE R
Sbjct: 186 -IAGSGDPEQTRR 197
>gb|AAF48896.1| (AE003510) CG7322 gene product [Drosophila melanogaster]
Length = 242
Score = 83.5 bits (203), Expect = 2e-15
Identities = 67/192 (34%), Positives = 95/192 (48%), Gaps = 15/192 (7%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL------GIKYIVVDLSTYEGIS 62
+L+TGA GIGQ L K+L G VI V R + L++L I+ + +DLS ++
Sbjct: 10 ILVTGAGAGIGQALVKQLASAGATVIAVARKPEQLQQLVAFDPVHIQPLQLDLSGWQA-- 67
Query: 63 KVRESLKGE--IDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEG 120
VRE L +D L+NNAG ++KP E + ++ + F VN A +T+ LL + +G
Sbjct: 68 -VREGLAKVPLLDGLVNNAGVAIIKPFEELTEQDFDTHFDVNIKAVFNVTQSLLPRLKDG 126
Query: 121 GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT---- 176
+V + S AS Y A+K AL + K L EL R I+V V P V T
Sbjct: 127 ASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVVLTKMGA 186
Query: 177 DFWKGAKLRGAL 188
D W G L
Sbjct: 187 DNWSDPAKSGPL 198
>gb|AAB08021.1| (U43704) aklaviketone reductase [Streptomyces sp. C5]
Length = 251
Score = 83.5 bits (203), Expect = 2e-15
Identities = 66/195 (33%), Positives = 95/195 (47%), Gaps = 16/195 (8%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL--GIKY---IVVDLSTYEG--- 60
V++TG GIG+ +A+ RG V+ VGR L E G K + VD++
Sbjct: 8 VIVTGGGSGIGRAVARAFAARGDRVLVVGRTAGPLAETVDGHKEAHTLAVDITDPAAPQA 67
Query: 61 -ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE 119
+ +VRE L G +DVL+NNA + L E +E N +APV+LT+ LLD +
Sbjct: 68 VVREVRERLGGVVDVLVNNAATAVFGHLGELDRTAVEAQVATNLVAPVLLTQALLDPLET 127
Query: 120 GGKVVFIISGASHVYTLDLPG---YGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
+V I A + PG YGA+K L + + EL RGI+V+ V P + T
Sbjct: 128 ASGLVVNIGSAGALGRRAWPGNAVYGAAKAGLDLLTRSWAVELGPRGIRVIGVAPGVIET 187
Query: 177 DFWKGAKLRGALSPE 191
GA +R +S E
Sbjct: 188 ----GAGVRAGMSQE 198
>sp|P37694|HETN_ANASP KETOACYL REDUCTASE HETN >gi|1075641|pir||C55210 hetN protein -
Anabaena sp. (strain PCC 7120) >gi|349207|gb|AAA22002.1|
(L22883) ketoacyl reductase [Anabaena PCC7120]
Length = 287
Score = 82.3 bits (200), Expect = 5e-15
Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 20/222 (9%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKAL------------KELGIKYIVVDLS 56
VLLTGAS G+G +A+ L + V+ V R++ L K + I + V + S
Sbjct: 9 VLLTGASRGLGVYIARALAKEQATVVCVSRSQSGLAQTCNAVKAAGGKAIAIPFDVRNTS 68
Query: 57 TYEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
+ + + + G IDVLINNAG + +S E++ +F N +A + LT+ LL
Sbjct: 69 QLSALVQQAQDIVGPIDVLINNAGIEINGTFANYSLAEIQSIFNTNLLAAIELTRLLLPS 128
Query: 117 IPE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQV 174
+ E G++V I S A Y ASK L + +EL G+ + V P V
Sbjct: 129 MMERGSGRIVNIASLAGKKGVAFNSVYSASKAGLIMWTDAMRQELVGTGVNISVVCPGYV 188
Query: 175 ATDFW------KGAKLRGALSPEYVARKIVNAIESDKRELFI 210
+ KL G +P+ VA +V AI++ E+ +
Sbjct: 189 SQTGMTVDTRVSAPKLAGISTPKSVANAVVKAIKNKTTEVIV 230
>emb|CAB94622.1| (AL359214) putative oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 250
Score = 81.5 bits (198), Expect = 8e-15
Identities = 66/191 (34%), Positives = 92/191 (47%), Gaps = 14/191 (7%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEV-IGVGRNEKALKEL--------GIKYI 51
MG L L+TGAS GIG+ +A+ L R G V + GRNE A KE G +
Sbjct: 1 MGVLAGRTALVTGASRGIGRGIAERLGRDGARVAVHYGRNEAAAKETVAAIEAGGGSAFT 60
Query: 52 V-VDLSTYEGISKVRESLKGE---IDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPV 107
+ DL + E +DVL+NNAG G +P+ E E + +F VN AP
Sbjct: 61 IRADLGAPGAAEALWEQFDRHADGLDVLVNNAGIGNTRPIGEIGEAEYDAVFTVNVKAPF 120
Query: 108 ILTKELLDFIPEGGKVVFIISGASHVYTL-DLPGYGASKVALHYMAKVLEEELKERGIKV 166
+ K + + +GG+VV I SG + + D Y +K AL ++ L + L RGI V
Sbjct: 121 FILKHGMGRLRDGGRVVNISSGLARTAVMPDNMAYAMTKGALDVFSRDLSKVLGTRGITV 180
Query: 167 LRVYPKQVATD 177
V P + TD
Sbjct: 181 NSVAPGIIDTD 191
>emb|CAC01636.1| (AL391072) putative ketoreductase [Streptomyces coelicolor A3(2)]
Length = 255
Score = 81.1 bits (197), Expect = 1e-14
Identities = 64/206 (31%), Positives = 94/206 (45%), Gaps = 15/206 (7%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG-----IKYIVVDLSTYEGISK 63
V++TGA GIG+ A G V+ VGR E LKE I + +D+ E K
Sbjct: 15 VIVTGAGTGIGRATAVAFAESGAHVLAVGRREALLKETAAAHSHIDVLAIDICGDEAPGK 74
Query: 64 VRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE- 119
V ++ G +D LINNAG V PL E + + + +N +AP +L +E L +
Sbjct: 75 VVDAAVERWGRLDHLINNAGATAVMPLAEAEKQTIVDLLALNVVAPSLLAREALPHLRRT 134
Query: 120 GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFW 179
G ++ + S H Y A+K A+ M + EL + G++V V P TD
Sbjct: 135 SGSIINLSSTYGHRPMAGGAHYSATKAAVEQMTRSWALELADEGVRVNSVAPGPTRTD-- 192
Query: 180 KGAKLRGALSPEYVARKIVNAIESDK 205
L L+PE A + A E D+
Sbjct: 193 --VMLHAGLTPE--AANDMYAYERDR 214
>pir||T41028 short chain dehydrogenase - fission yeast (Schizosaccharomyces
pombe) >gi|3218393|emb|CAA19583.1| (AL023860) short
chain dehydrogenase [Schizosaccharomyces pombe]
Length = 292
Score = 80.8 bits (196), Expect = 1e-14
Identities = 59/191 (30%), Positives = 96/191 (49%), Gaps = 10/191 (5%)
Query: 6 YMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKAL-----KELGIKYIVVDLSTYEG 60
+ VL+TG+S G+G L K + +GY VI R + K L +K V D+ + E
Sbjct: 5 FSTVLITGSSKGLGYALVKVGLAQGYNVIACSRAPDTITIEHSKLLKLKLDVTDVKSVET 64
Query: 61 ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE- 119
K + G +D++INNAG+GLV ++ EE+ VN +TKE L+ + E
Sbjct: 65 AFKDAKRRFGNVDIVINNAGYGLVGEFESYNIEEMHRQMNVNFWGVAYITKEALNLMRES 124
Query: 120 --GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKER-GIKVLRVYPKQVAT 176
GG+++ I S A + + L Y ASK A+ +++ + EL I + V P + T
Sbjct: 125 GKGGRILQISSVAGYYPSPCLSMYNASKFAVEGLSQTIMRELDPNWNIAITIVQPGGMQT 184
Query: 177 DFWKGAKLRGA 187
+ W + ++ A
Sbjct: 185 E-WASSNMQWA 194
>gi|6671688 carbonyl reductase 2 [Mus musculus] >gi|113986|sp|P08074|CBR2_MOUSE
LUNG CARBONYL REDUCTASE [NADPH] (NADPH-DEPENDENT
CARBONYL REDUCTASE) (LCR) (ADIPOCYTE P27 PROTEIN) (AP27)
>gi|90271|pir||A28053 carbonyl reductase (NADPH) (EC
1.1.1.184) - mouse >gi|1827689|pdb|1CYD|A Chain A,
Carbonyl Reductase Complexed With Nadph And 2-Propanol
>gi|1827690|pdb|1CYD|B Chain B, Carbonyl Reductase
Complexed With Nadph And 2-Propanol
>gi|1827691|pdb|1CYD|C Chain C, Carbonyl Reductase
Complexed With Nadph And 2-Propanol
>gi|1827692|pdb|1CYD|D Chain D, Carbonyl Reductase
Complexed With Nadph And 2-Propanol
>gi|50004|emb|CAA30309.1| (X07411) Ap27 protein (AA 1 -
244) [Mus musculus] >gi|699608|dbj|BAA05120.1| (D26123)
carbonyl reductase [Mus musculus]
Length = 244
Score = 80.8 bits (196), Expect = 1e-14
Identities = 64/200 (32%), Positives = 101/200 (50%), Gaps = 16/200 (8%)
Query: 7 MRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-----GIKYIVVDLSTYEGI 61
+R L+TGA GIG++ K L G +V+ V R L L GI+ + VDL ++
Sbjct: 8 LRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWDAT 67
Query: 62 SKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL--DFIPE 119
K + G +D+L+NNA +++P LE + E + F VN + V +++ D I
Sbjct: 68 EKALGGI-GPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVN-LRSVFQVSQMVARDMINR 125
Query: 120 G--GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATD 177
G G +V + S +HV +L Y ++K A+ + K + EL I+V V P V TD
Sbjct: 126 GVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVLTD 185
Query: 178 FWKGAKLRGALSPEYVARKI 197
K + + PE+ ARK+
Sbjct: 186 MGK----KVSADPEF-ARKL 200
>emb|CAC11583.1| (AL445064) 3-oxoacyl-[acyl-carrier-protein] reductase related
protein [Thermoplasma acidophilum]
Length = 250
Score = 80.8 bits (196), Expect = 1e-14
Identities = 55/180 (30%), Positives = 92/180 (50%), Gaps = 14/180 (7%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVI-----GVGRNEKALKELGIKY-----IVVDLSTYE 59
++TG+ GIG+E+A L ++G V+ V + L E+ KY + D+ST
Sbjct: 7 VVTGSGRGIGREIAVYLAKQGANVVVNVKKRVEDGNETLAEVR-KYSNGIMVQADVSTRA 65
Query: 60 GISKVRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
G + E + G+ D+L+NNAG G+ P L+ +E M N ++ + T+EL
Sbjct: 66 GARHIAEETQKEYGQCDILVNNAGLGIGMPFLDSDDRLIEKMVSTNYLSAIYCTQELTKI 125
Query: 117 IPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
+PEGG ++ + S A + L YG+ K A+ + + L E K++ I+V + P V T
Sbjct: 126 MPEGGSIIMMASLAGIRPMVSLSLYGSLKAAIIKLTEYLALEFKQKKIRVNSIAPSIVKT 185
>dbj|BAB11656.1| (AB013395) contains similarity to dehydrogenase~gene_id:MQN23.14
[Arabidopsis thaliana]
Length = 341
Score = 80.0 bits (194), Expect = 2e-14
Identities = 61/178 (34%), Positives = 93/178 (51%), Gaps = 20/178 (11%)
Query: 9 VLLTGAS-GGIGQELAKELIRRGYEVIGVGRNEKALKEL--GIKYIV--VDLSTYEGISK 63
VL+TG S GGIG LA+E G V+ R++K + EL K+ V +D+ + + +SK
Sbjct: 11 VLITGCSQGGIGHALAREFSANGCRVVATSRSQKTMTELEKDSKFFVQELDVQSEQSVSK 70
Query: 64 VRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFI--P 118
V + G+IDVL+NNAG + PL E ++ F N + + +T+ ++ +
Sbjct: 71 VVSKVIDKFGQIDVLVNNAGVQCIGPLAEIPISAMDYTFNTNVLGSMRMTQAVVPHMASK 130
Query: 119 EGGKVVFIISGASHVYTLDLPG-----YGASKVALHYMAKVLEEELKERGIKVLRVYP 171
+ GK+V I S ++ PG Y ASK ALH + L ELK GI V+ + P
Sbjct: 131 KKGKIVNIGS-----ISIMAPGPWAGVYTASKAALHALTDTLRLELKPFGIDVINIVP 183
>gb|AAA65202.1| (L35560) daunorubicin-doxorubicin polyketide synthase [Streptomyces
peucetius] >gi|1093559|prf||2104259A dnrH gene
[Streptomyces peucetius]
Length = 251
Score = 79.6 bits (193), Expect = 3e-14
Identities = 63/195 (32%), Positives = 91/195 (46%), Gaps = 16/195 (8%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-----GIKYIVVDLSTYEG--- 60
V++TG GIG+ +A+ RG V+ VGR L E + VD++
Sbjct: 8 VIVTGGGSGIGRAVARAFAARGDRVLVVGRTAGPLAETVDGHKDAHTLAVDITDPAAPEA 67
Query: 61 -ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE 119
+ +VRE L G +DVL+NNA L E +E N +APV+LT+ LL +
Sbjct: 68 VVREVRERLGGVVDVLVNNAATAAFGHLGELHRTAVEAQVATNLVAPVLLTQALLGPLET 127
Query: 120 GGKVVFIISGASHVYTLDLPG---YGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
+V I A + PG YGA+K L + + EL RGI+V+ V P + T
Sbjct: 128 ASGLVVNIGSAGALGRRAWPGNAVYGAAKAGLDLLTRSWAVELGPRGIRVVGVAPGVIGT 187
Query: 177 DFWKGAKLRGALSPE 191
GA +R +S E
Sbjct: 188 ----GAGVRAGMSQE 198
>gb|AAF01806.1|AF187532_2 (AF187532) C-7 ketoreductase [Streptomyces nogalater]
Length = 281
Score = 79.6 bits (193), Expect = 3e-14
Identities = 59/196 (30%), Positives = 97/196 (49%), Gaps = 15/196 (7%)
Query: 7 MRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG-----IKYIVVDLSTYEGI 61
+ V++TG GIG+ A+ +G +V+ VGR E AL + ++ +V D+++ +G
Sbjct: 37 LAVIVTGGGSGIGRATARAFAAQGAKVLVVGRTEDALAQTAEGCADMRVLVADVASPDGP 96
Query: 62 SKVRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIP 118
V + G IDVL+NNA ++ L + + F N AP+ L + L +
Sbjct: 97 QAVVNAALREFGRIDVLVNNAAVAGMETLQTVDRDAVARQFGTNLTAPLFLVQSALGALE 156
Query: 119 EGGKVVFIISGASHVYTLDLPG---YGASKVALHYMAKVLEEELKERGIKVLRVYPKQVA 175
+ +V + A+ + P YGASKVAL Y+ + EL RGI+V+ V P +
Sbjct: 157 KSRGIVVNVGTAATLGLRAAPTGALYGASKVALDYLTRTWAVELAPRGIRVVGVAPGVID 216
Query: 176 TDFWKGAKLRGALSPE 191
T G +R ++PE
Sbjct: 217 T----GIGVRMGMTPE 228
>pir||G83473 probable short-chain dehydrogenase PA1379 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947323|gb|AAG04768.1|AE004567_7 (AE004567) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 277
Score = 79.6 bits (193), Expect = 3e-14
Identities = 62/197 (31%), Positives = 94/197 (47%), Gaps = 14/197 (7%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL---------GIKYIVVDLSTYE 59
+L+TGAS G GQ LA+E + G+ V+G R+E+A L G V DL+ E
Sbjct: 7 LLITGASSGFGQALAREALDAGHRVVGTVRSEEARSALEAVAPGQAFGRLLDVTDLAAIE 66
Query: 60 GISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFI-- 117
E G +DVL+N+AG+G L E E+ F+VN V + + +L ++
Sbjct: 67 PTVAAIERDIGPLDVLVNSAGYGHEGILEESPLAEMRRQFEVNLFGAVAMIQAVLPYMRR 126
Query: 118 PEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATD 177
G ++ I S ++ + Y SK AL +++ L +E+ GI V V P TD
Sbjct: 127 RRRGHILNITSMGGYITMPGIAYYCGSKFALEGVSEALGKEVAGLGIAVTAVAPGSFRTD 186
Query: 178 FWKGAKLRGALSPEYVA 194
W G + SP +A
Sbjct: 187 -WAGRSM--VRSPRTIA 200
>gb|AAD44003.1| (U59485) AtsC [Agrobacterium tumefaciens]
Length = 254
Score = 78.8 bits (191), Expect = 5e-14
Identities = 64/194 (32%), Positives = 97/194 (49%), Gaps = 26/194 (13%)
Query: 10 LLTGASGGIGQELAKELIRRGYEV-IG---VGRNEKALKEL--------GIKYIVVDLST 57
L+TGA+ GIG +A++L G+ V +G + R E A EL ++ V D ++
Sbjct: 15 LVTGANKGIGLAIARQLGAAGHTVWLGCRDMSRGEMAAFELRENGVDARAVQLDVTDDAS 74
Query: 58 YEGISKVRESLKGEIDVLINNAG--FGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD 115
+K ES G +DVL+NNAG FG L E S +E++ MF N + +T+ L
Sbjct: 75 ASSAAKTIESEVGHLDVLVNNAGLMFGSPPSLAEESIDEIQQMFNTNVFGVMRVTQAFLP 134
Query: 116 FI--PEGGKVVFIISGASHV----------YTLDLPGYGASKVALHYMAKVLEEELKERG 163
+ + ++V + SG S + +T+ GY ASK AL+ + L +EL G
Sbjct: 135 LLRKSKAARIVMMSSGLSSLTDALDMRSETWTVGFGGYCASKTALNMLTVKLAKELDREG 194
Query: 164 IKVLRVYPKQVATD 177
IKV V P +TD
Sbjct: 195 IKVNAVDPGLTSTD 208
>gi|7705905 retinal short-chain dehydrogenase/reductase retSDR2 [Homo sapiens]
>gi|6318544|gb|AAF06939.1|AF126780_1 (AF126780) retinal
short-chain dehydrogenase/reductase retSDR2 [Homo
sapiens]
Length = 300
Score = 78.8 bits (191), Expect = 5e-14
Identities = 69/222 (31%), Positives = 105/222 (47%), Gaps = 19/222 (8%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKE-------LGIKY--IVVDLSTYE 59
VL+TGA GIG+ A E + +++ N+ L+E LG K VVD S E
Sbjct: 39 VLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNRE 98
Query: 60 GISKVRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
I + +K G++ +L+NNAG L ++E F+VN +A TK L
Sbjct: 99 DIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPA 158
Query: 117 IPEG--GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEE---LKERGIKVLRVYP 171
+ + G +V + S A HV L Y +SK A K L +E L+ G+K + P
Sbjct: 159 MTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCP 218
Query: 172 KQVATDFWK--GAKLRGALSPEYVARKIVNAIESDKRELFIP 211
V T F K L L PE V ++++ I ++++ +FIP
Sbjct: 219 NFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIP 260
>pir||F82378 oxidoreductase, short-chain dehydrogenase/reductase family VCA1108
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9658554|gb|AAF96999.1| (AE004435) oxidoreductase,
short-chain dehydrogenase/reductase family [Vibrio
cholerae]
Length = 265
Score = 78.8 bits (191), Expect = 5e-14
Identities = 66/232 (28%), Positives = 111/232 (47%), Gaps = 27/232 (11%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGI--------KYIVVDLSTYEG 60
VLLTGASGGIG+ +A L RG +I + R+ + L+ L + + DL++ G
Sbjct: 8 VLLTGASGGIGEPIAHTLAARGARLILLARDAQKLEALRQSLPKPELHRVVSADLTSEAG 67
Query: 61 ISKVRESLKG------EIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL 114
+ +++ ++ I V+INNAG L S E ++ +N + P+ + +L
Sbjct: 68 MEQLQALVEELNRAQQRIAVVINNAGTNQFCLLARRSMESVQRELALNLMTPIQIMHHVL 127
Query: 115 DFIPEGGKVVFIISGASHVYTLDLPGYG---ASKVALHYMAKVLEEELKERGIKVLRVYP 171
+ K +I+ S + + PGY A+K LH ++ + EL G+KVL + P
Sbjct: 128 QW---SRKPQMVINIGSSLGAIGYPGYASYCAAKAGLHRFSEAMNRELAGTGMKVLYLAP 184
Query: 172 KQVATDFWKGA--KLRGAL-----SPEYVARKIVNAIESDKRELFIPWYLKL 216
+ T A +L AL P VA ++ IE+++ ++I W KL
Sbjct: 185 RATNTSLNSEAVQQLNRALGNRSDEPSLVAAQVAKMIETEQNVMWIGWPEKL 236
>gb|AAF73457.1|AF264025_8 (AF264025) putative aklaviketone reductase; AknU [Streptomyces
galilaeus]
Length = 267
Score = 78.0 bits (189), Expect = 9e-14
Identities = 59/180 (32%), Positives = 85/180 (46%), Gaps = 12/180 (6%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-----GIKYIVVDLSTYEGISK 63
V++TG GIG+ A RG V+ VGR L GI + DL+ +G
Sbjct: 24 VIVTGGGTGIGRATAHAFADRGDRVLVVGRTAATLAGTAEGHPGISVLTADLTDPDGPRA 83
Query: 64 VRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFI-PE 119
+ ++ G IDVL+NNA G L E E F N +AP++LT++ LD + +
Sbjct: 84 ITDAALDALGRIDVLVNNAATGGFAGLAETEPEAAREQFDSNLLAPLLLTRQTLDALSAD 143
Query: 120 GGKVVFIISGASHVYTLDLPG---YGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
GG V I A + P YGA+K L ++ + EL RGI+VL + P + T
Sbjct: 144 GGGTVLNIGSAGALGRRAWPQNGVYGAAKAGLDFLTRTWAVELAPRGIRVLGLAPGVIDT 203
>emb|CAB65876.1| (AL109630) /match=(desc:""3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (EC 1.1.1.100) (3-KETOACYL- ACYL CARRIER
PROTEIN REDUCTASE)"", species:""Escherichia coli"",
ranges:(query:124808..124897,
target:SWISS-PROT::P25716:30..1, score:""84.00""),
(query:12>
Length = 251
Score = 77.6 bits (188), Expect = 1e-13
Identities = 63/194 (32%), Positives = 97/194 (49%), Gaps = 14/194 (7%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRN-------EKALKELGIKYIVVDLSTYEGI 61
V++TGAS GIG +A+ L R G + VGRN +K+LK + +V D+ T +
Sbjct: 8 VIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGTQAEIVVADV-TKDAD 66
Query: 62 SKVRESLK--GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL-DFIP 118
+ V+++L G IDVL+NNAG L++ EE + + N ++LTK +L +
Sbjct: 67 AIVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLTKAVLPHLLK 126
Query: 119 EGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDF 178
G VV + S A YG SK AL K++ E+ +G++V V P V T+
Sbjct: 127 TKGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNPGFVVTNI 186
Query: 179 WKGAKLRGALSPEY 192
+ G + EY
Sbjct: 187 HRNI---GIVDEEY 197
>pir||D70948 hypothetical protein Rv3174 - Mycobacterium tuberculosis (strain
H37RV) >gi|2827584|emb|CAA16639.1| (AL021646)
hypothetical protein Rv3174 [Mycobacterium tuberculosis]
Length = 235
Score = 77.3 bits (187), Expect = 2e-13
Identities = 57/202 (28%), Positives = 96/202 (47%), Gaps = 4/202 (1%)
Query: 9 VLLTGASGGIGQELAKELI-RRGYEVIGVGRNEKALKELGIKYIVVDLSTYEGISKVRES 67
VL+TGA+ G+G+E +L+ R+ +V RN A+ + I + L + +S +
Sbjct: 9 VLVTGANRGMGREYVAQLLGRKVAKVYAATRNPLAIDVSDPRVIPLQLDVTDAVSVAEAA 68
Query: 68 -LKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEGGKVVFI 126
L ++ +LINNAG +L+ L G + N P+ L D I E +
Sbjct: 69 DLATDVGILINNAGISRASSVLDKDTSALRGELETNLFGPLALASAFADRIAERSGAIVN 128
Query: 127 ISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWKGAKLRG 186
+S L + YG SK A+ + + EL RG++V+ VY V TD + A
Sbjct: 129 VSSVLAWLPLGM-SYGVSKAAMWSATESMRIELAPRGVQVVGVYVGLVDTDMGRFADAPK 187
Query: 187 ALSPEYVARKIVNAIESDKREL 208
+ P V R++++ IE+ K ++
Sbjct: 188 S-DPADVVRQVLDGIEAGKEDV 208
>pir||S51948 hypothetical protein - Agrobacterium tumefaciens
>gi|992587|emb|CAA82807.1| (Z29717) f [Agrobacterium
tumefaciens]
Length = 344
Score = 77.3 bits (187), Expect = 2e-13
Identities = 65/209 (31%), Positives = 99/209 (47%), Gaps = 15/209 (7%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEV-IGVGRNEKALKELGI--------KYIVVDLSTYE 59
+L+TGASGGI + + L+RRG+ + +G EK G ++ DL T E
Sbjct: 91 ILVTGASGGIDKAIDDNLMRRGFRLSLGARSVEKLEATFGFQNESLHFARFEAEDLQTME 150
Query: 60 GISKVRESLKGEIDVLINNAGFGLVKPLLEH-SWEELEGMFKVNAIAPVILTKELLDFIP 118
G ID L+NNAG G L E +E+LE +K+NA AP+ + L +
Sbjct: 151 EWVSTAMIKFGRIDGLVNNAGDGTRVALAEGIDYEQLERQWKINAGAPLRMIMLCLPQLA 210
Query: 119 E--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
+ G++V IIS + GY +K AL + K + E G++ + + P VAT
Sbjct: 211 KSGSGRIVNIISMSGQRVLNSFVGYNMTKHALSGLTKTAQHVGWESGVRTMEICPGYVAT 270
Query: 177 DF--WKG-AKLRGALSPEYVARKIVNAIE 202
W + G + PE++A + AIE
Sbjct: 271 KMSAWTDEIEDDGKIQPEHIAELVRQAIE 299
>emb|CAB51140.1| (Y18818) oxidoreductase of short-chain [Streptomyces lividans]
Length = 276
Score = 76.5 bits (185), Expect = 3e-13
Identities = 54/182 (29%), Positives = 88/182 (47%), Gaps = 11/182 (6%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL---------GIKYIVVDLSTYEG 60
L+TGAS G G+ +A+ + G V+G R +AL +L ++ V D +
Sbjct: 6 LITGASSGFGRAIAEAALADGDVVVGAARRPEALDDLVAAHPDQMEALRLDVADTAAAGD 65
Query: 61 ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE- 119
+ + G +DVL+NNAG V L E +EL +F V+ P LT+ +L + E
Sbjct: 66 AVRDVVARHGRVDVLVNNAGRTHVGALEETGEDELRALFDVHVFGPAALTRAVLPSMRER 125
Query: 120 -GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDF 178
G +V + S + Y +K AL M++ L +E+++ GIKV+ V P T
Sbjct: 126 RSGAIVQMSSMGGQMSFAGFSAYSGTKFALEGMSEGLADEVRDFGIKVVIVEPGSFRTGL 185
Query: 179 WK 180
++
Sbjct: 186 FE 187
>pir||T32196 hypothetical protein T01G6.1 - Caenorhabditis elegans
>gi|10864463|gb|AAG24176.1| (AF022978) Contains
similarity to Pfam domain: PF00678 (adh_short_C2),
Score=10.4, E-value=0.05, N=1 [Caenorhabditis elegans]
Length = 279
Score = 76.5 bits (185), Expect = 3e-13
Identities = 63/217 (29%), Positives = 111/217 (51%), Gaps = 26/217 (11%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL------------GIKYIVVDLS 56
V++TG+S GIG+ A + G +V GRN + L+ + +V +L+
Sbjct: 9 VIITGSSSGIGRATAVLFAKNGAQVTITGRNAEKLEATKKKLLKVVKTPDSVNVVVANLT 68
Query: 57 TYEGISKVRESLK---GEIDVLINNAGFGLVKPLL--EHSWEELEGMFKVNAIAPVILTK 111
+G ++ +S G+ID+LINNAG +V + + S + F++N A V + K
Sbjct: 69 DAQGQDQIIQSAVKKFGKIDILINNAGANVVDGTVNTDQSIDLYHKTFQINFQAVVEMVK 128
Query: 112 ELLDFIPEG-GKVVFIISGASHVYTLDL-PGYGASKVALHYMAKVLEEELKERGIKVLRV 169
+ ++ E G++V + S A+ + + P Y A+K AL+ + + +L ++G++V V
Sbjct: 129 KTKKYLIESKGEIVNVSSIAAGPQAVSMSPYYAAAKAALNQYTRCVALDLIKQGVRVNSV 188
Query: 170 YPKQVATDFWKGAKLRGALS-PEYVARKIVNAIESDK 205
P +AT+F GA+ PE +KIVN S+K
Sbjct: 189 SPGIIATNF------MGAMGVPEQAQKKIVNLFASEK 219
>pir||T45275 oxidoreductase of short-chain [imported] - Streptomyces coelicolor
(A3(2)) >gi|5541922|emb|CAB51136.1| (Y18817)
oxidoreductase of short-chain [Streptomyces coelicolor
A3(2)]
Length = 276
Score = 76.5 bits (185), Expect = 3e-13
Identities = 54/182 (29%), Positives = 88/182 (47%), Gaps = 11/182 (6%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL---------GIKYIVVDLSTYEG 60
L+TGAS G G+ +A+ + G V+G R +AL +L ++ V D +
Sbjct: 6 LITGASSGFGRAIAEAALADGDVVVGAARRPEALDDLVAAHPDQMEALRLDVADTAAAGD 65
Query: 61 ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE- 119
+ + G +DVL+NNAG V L E +EL +F V+ P LT+ +L + E
Sbjct: 66 AVRDVVARHGRVDVLVNNAGRTHVGALEETGEDELRALFDVHVFGPAALTRAVLPSMRER 125
Query: 120 -GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDF 178
G +V + S + Y +K AL M++ L +E+++ GIKV+ V P T
Sbjct: 126 RSGAIVQMSSMGGQMSFAGFSAYSGTKFALEGMSEGLADEVRDFGIKVVIVEPGSFRTGL 185
Query: 179 WK 180
++
Sbjct: 186 FE 187
>sp|Q29529|CBR2_PIG LUNG CARBONYL REDUCTASE [NADPH] (NADPH-DEPENDENT CARBONYL
REDUCTASE) (LCR) >gi|543092|pir||JN0703 carbonyl
reductase (NADPH) (EC 1.1.1.184) - pig
>gi|416425|dbj|BAA03963.1| (D16511) carbonyl reductase
[Sus scrofa]
Length = 244
Score = 75.3 bits (182), Expect = 6e-13
Identities = 61/201 (30%), Positives = 95/201 (46%), Gaps = 18/201 (8%)
Query: 7 MRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-----GIKYIVVDLSTYEGI 61
+R L+TGA GIG++ K L G V+ V R L L GI+ + VDL +E
Sbjct: 8 LRALVTGAGKGIGRDTVKALHVSGARVVAVTRTNGDLVSLSQECPGIEPVCVDLGDWEAT 67
Query: 62 SKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVN-----AIAPVILTKELLDF 116
+ + G +D+L+NNA L++P L+ + E + F VN ++ ++ +
Sbjct: 68 ERALGGV-GPVDLLVNNAAVALMQPFLDTTKEVFDRSFNVNLRSVFQVSQIVARSMIERG 126
Query: 117 IPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
+P G +V + S SHV L Y ++K A+ + K + EL I+V V P V T
Sbjct: 127 VP--GSIVNVSSMVSHVTYPGLAAYSSTKGAMTMLTKSMAMELGPHKIRVNSVNPTVVLT 184
Query: 177 DFWKGAKLRGALSPEYVARKI 197
A R S +ARK+
Sbjct: 185 -----AMGRSVTSDPELARKL 200
>gb|AAB82041.1| (U59236) unknown [Synechococcus PCC7942]
Length = 245
Score = 75.3 bits (182), Expect = 6e-13
Identities = 67/219 (30%), Positives = 102/219 (45%), Gaps = 21/219 (9%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG----------IKY 50
M FL VL+TGAS GIG A + G+ ++ +GR+ L+ + +
Sbjct: 4 MSFLPSPFVLITGASSGIGAATAHAFAQAGWSLLLLGRDRGRLQSVAESARSQGAAAVAT 63
Query: 51 IVVDLSTYEGISKVRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPV 107
+DL+ I L G DVLINNAG PL S +LE +F +N +P+
Sbjct: 64 YSLDLTNLTAIGPAIAQLVEQFGVPDVLINNAGTAQTGPLATLSLSDLECIFALNVHSPL 123
Query: 108 ILTKELLDFI--PEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIK 165
++ + LL + + G ++ + S A+ D Y ASK AL ++VL E + GI+
Sbjct: 124 LVVQALLPGMRQRQRGLILNVASIAAQQAFPDWGAYCASKSALAAWSRVLAAEERSHGIR 183
Query: 166 VLRVYPKQVATDFWK----GAKL--RGALSPEYVARKIV 198
V + P V T W GA + L PE VA+ ++
Sbjct: 184 VSLICPGSVDTALWDQPSVGANFDRQAMLRPETVAQVLL 222
>emb|CAB51900.1| (Y19033) 1,3,6,8-tetrahydroxynaphthalene reductase [Aspergillus
fumigatus] >gi|6090729|gb|AAF03314.1|AF099736_1
(AF099736) 1,3,6,8-tetrahydroxynaphthalene reductase
[Aspergillus fumigatus]
Length = 273
Score = 75.3 bits (182), Expect = 6e-13
Identities = 56/187 (29%), Positives = 95/187 (49%), Gaps = 19/187 (10%)
Query: 10 LLTGASGGIGQELAKELIRRGYEV-IGVGRNEKALKE-------LGIKYIVV--DLSTYE 59
L+TG GIG +A EL RRG V I G + K+ +E +G + + + DL+
Sbjct: 16 LVTGGGRGIGAGIALELARRGASVAINYGHSAKSAQEVVEAIQAIGRQAVAIQADLTCVP 75
Query: 60 GI-SKVRESLK--GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
I S ++E ++ G +D++++N+G KPL E + E+ +F +N A + + + D
Sbjct: 76 NIESLIQEVVRHFGRLDIVVSNSGMEKFKPLEETTLEDFNEVFNLNTRAQMFVARYAYDH 135
Query: 117 IPEGGKVVFIISGASHVYTLDLPG---YGASKVALHYMAKVLEEELKERGIKVLRVYPKQ 173
I GG+V+ + S A+ L +PG Y SK A+ + L + +G V + P
Sbjct: 136 IQPGGRVILMSSIAA---GLGVPGHALYAGSKAAIEGFTRCLAADFGRKGCTVNAIAPAG 192
Query: 174 VATDFWK 180
V +D W+
Sbjct: 193 VKSDMWR 199
>pir||D75522 oxidoreductase, short-chain dehydrogenase/reductase family -
Deinococcus radiodurans (strain R1)
>gi|6458092|gb|AAF09990.1|AE001901_5 (AE001901)
oxidoreductase, short-chain dehydrogenase/reductase
family [Deinococcus radiodurans]
Length = 227
Score = 75.3 bits (182), Expect = 6e-13
Identities = 58/172 (33%), Positives = 86/172 (49%), Gaps = 7/172 (4%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALK----ELGIKYIVVDLSTYEGISKVR 65
L+TGASGGIG LA++L +++I GR L E+G + +DL E +
Sbjct: 7 LITGASGGIGSALARQLAPT-HDLILTGRGGAELDALCAEVGATPLTLDLIRPEAFAAAL 65
Query: 66 ESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFI-PEGGKVV 124
+ G + +++NAG + + E E VN +AP LT+ LL + E G V+
Sbjct: 66 AGV-GRVTNVVHNAGVVELGRVAEQGHEVWTHTLAVNTVAPAELTRLLLPRVREERGTVL 124
Query: 125 FIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
F+ SGA + Y ASK AL +A L +E G++V VYP + AT
Sbjct: 125 FVNSGAGLRANPEWGSYAASKFALKALADALRDEEAPHGVRVSTVYPGRTAT 176
>pir||C75365 daunorubicin C-13 ketoreductase - Deinococcus radiodurans (strain
R1) >gi|6459467|gb|AAF11255.1|AE002011_6 (AE002011)
daunorubicin C-13 ketoreductase [Deinococcus
radiodurans]
Length = 400
Score = 75.3 bits (182), Expect = 6e-13
Identities = 68/233 (29%), Positives = 112/233 (47%), Gaps = 41/233 (17%)
Query: 8 RVLLTGASGGIGQELAKELIRRGYEVIGVGRN----EKALKELGIK-YIVVDLSTYEGIS 62
R+L+TGA+GGIG E A+EL RG +V+ VGR+ + E+G ++ DLS +
Sbjct: 133 RILITGATGGIGLETARELAGRGAQVVIVGRDPGRTARVAAEVGAAGTLLADLSELVQVE 192
Query: 63 KVRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE 119
+ + GE+DVL+NNA G + + S E +E + +N +AP +LT+ELL +
Sbjct: 193 RAAAEYRERFGELDVLVNNA--GALHRERQESREGIELTWALNHLAPFLLTRELLPLLRR 250
Query: 120 GGKV------VFIISGASHVY-------------TLDLPGYGASKVALHYMAKVLEEELK 160
+ V ++ A+HV P Y SK+A A+ L +
Sbjct: 251 SSETRRVPARVVTVASAAHVVGRIRFDDPEFRRGYAAWPAYAQSKLANILFARELAR--R 308
Query: 161 ERGIKVLRVYPKQVATDFWK----------GAKLRGALSPEYVARKIVNAIES 203
E + + ++P VA+ F K G R +L+PE A+ ++A+ +
Sbjct: 309 EPSVLSVSLHPGMVASGFGKNGGGRFAQAYGLLDRFSLTPEQGAQTSLHAVSA 361
>pir||S56475 hypothetical protein f261a - Escherichia coli
>gi|537091|gb|AAA97146.1| (U14003) ORF_f261a
[Escherichia coli]
Length = 261
Score = 74.9 bits (181), Expect = 8e-13
Identities = 57/184 (30%), Positives = 89/184 (47%), Gaps = 9/184 (4%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEV--IGVGRNEKALK---ELGIKYIVVDL 55
MG VL+ G S GIG + + + G V G + A + E G + D
Sbjct: 1 MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDS 60
Query: 56 STYEG-ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL 114
+ + I VR+S G +D+L+ NAG G+ LE + ++++ +FK+N AP + E
Sbjct: 61 ADRDAVIDVVRKS--GALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAA 118
Query: 115 DFIPEGGKVVFIIS-GASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQ 173
+PEGG+++ I S + + Y ASK AL MA+ L + RGI + V P
Sbjct: 119 RQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGP 178
Query: 174 VATD 177
+ TD
Sbjct: 179 IDTD 182
>sp|P39333|YJGI_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN PYRL-ARGI INTERGENIC REGION
>gi|7431013|pir||D65237 hypothetical 24.6 kD protein in
pyrL-argI intergenic region - Escherichia coli (strain
K-12) >gi|2367365|gb|AAC77206.1| (AE000495) putative
oxidoreductase [Escherichia coli K12]
Length = 237
Score = 74.9 bits (181), Expect = 8e-13
Identities = 57/184 (30%), Positives = 89/184 (47%), Gaps = 9/184 (4%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEV--IGVGRNEKALK---ELGIKYIVVDL 55
MG VL+ G S GIG + + + G V G + A + E G + D
Sbjct: 1 MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDS 60
Query: 56 STYEG-ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL 114
+ + I VR+S G +D+L+ NAG G+ LE + ++++ +FK+N AP + E
Sbjct: 61 ADRDAVIDVVRKS--GALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAA 118
Query: 115 DFIPEGGKVVFIIS-GASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQ 173
+PEGG+++ I S + + Y ASK AL MA+ L + RGI + V P
Sbjct: 119 RQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGP 178
Query: 174 VATD 177
+ TD
Sbjct: 179 IDTD 182
>gb|AAF45573.1| (AE003419) EG:BACR7A4.14 gene product [Drosophila melanogaster]
Length = 270
Score = 74.9 bits (181), Expect = 8e-13
Identities = 58/173 (33%), Positives = 89/173 (50%), Gaps = 11/173 (6%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRN-------EKALKELGIKYIVVDLSTYEGI 61
V++TGAS GIG +A+ L R G + VGRN +K+LK + +V D+ T +
Sbjct: 8 VIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGTQAEIVVADV-TKDAD 66
Query: 62 SKVRESLK--GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL-DFIP 118
+ V+++L G IDVL+NNAG L++ EE + + N ++LTK +L +
Sbjct: 67 AIVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLTKAVLPHLLK 126
Query: 119 EGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYP 171
G VV + S A YG SK AL K++ E+ +G++V V P
Sbjct: 127 TKGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNP 179
>gi|6755380 retinal short-chain dehydrogenase/reductase 1 [Mus musculus]
>gi|3777434|emb|CAA64602.1| (X95281) retinal short-chain
dehydrogenase/reductase [Mus musculus]
Length = 302
Score = 74.5 bits (180), Expect = 1e-12
Identities = 69/233 (29%), Positives = 113/233 (47%), Gaps = 29/233 (12%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGV-GRNEKALKE-------LGIK--YIVVDLSTY 58
VL+TG GIG+ LA+E RG I + GR EK LKE +G + Y + D+
Sbjct: 41 VLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNR 100
Query: 59 EGISKVRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD 115
E + ++ ++++ G+I +L+NNA K L++ + L VN + TK L
Sbjct: 101 EEVYQMAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLP 160
Query: 116 FIPE--GGKVVFIISGASHVYTLD-LPG---YGASKV-ALHYMAKVLEEELKERGIKVLR 168
+ E G +V + S V L +PG Y SK A +M + L G+
Sbjct: 161 RMLELQNGHIVCLNS----VLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATT 216
Query: 169 VYPKQVATDFWKGAKLR-----GALSPEYVARKIVNAIESDKRELFIPWYLKL 216
V P +T+ ++G ++R L PE VAR+ V+A++ ++ L +PW + +
Sbjct: 217 VLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVDAVQQNQALLLLPWTMNI 269
>gi|7705925 carbonyl reductase [Homo sapiens]
>gi|6523809|gb|AAF14864.1|AF113123_1 (AF113123) carbonyl
reductase [Homo sapiens]
Length = 244
Score = 74.5 bits (180), Expect = 1e-12
Identities = 61/183 (33%), Positives = 91/183 (49%), Gaps = 11/183 (6%)
Query: 3 FLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-----GIKYIVVDLST 57
FL RVL+TGA GIG+ + L G V+ V R + L L GI+ + VDL
Sbjct: 4 FLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGD 63
Query: 58 YEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL--D 115
+E + S+ G +D+L+NNA L++P LE + E + F+VN + VI +++
Sbjct: 64 WEATERALGSV-GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVN-LRAVIQVSQIVARG 121
Query: 116 FIPEG--GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQ 173
I G G +V + S S + Y ++K AL + KV+ EL I+V V P
Sbjct: 122 LIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTV 181
Query: 174 VAT 176
V T
Sbjct: 182 VMT 184
>pir||A82604 oxidoreductase XF2082 [imported] - Xylella fastidiosa (strain
9a5c) >gi|9107202|gb|AAF84881.1|AE004023_17 (AE004023)
oxidoreductase [Xylella fastidiosa]
Length = 268
Score = 74.5 bits (180), Expect = 1e-12
Identities = 59/191 (30%), Positives = 94/191 (48%), Gaps = 8/191 (4%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRN-EKALKELGIKYIVVDL----STYEGISK 63
V++TG S GIG+ A L ++G +V G RN EKA G+ + +D+ S GI
Sbjct: 7 VVITGVSSGIGRATALILAKQGCQVFGTVRNAEKAQAIPGVVLVEMDIRDDVSVERGIQN 66
Query: 64 VRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE--GG 121
+ K IDVL+NNAG L+ E S E + +F N + + +L + E G
Sbjct: 67 IMAQAK-RIDVLVNNAGVTLLGATEETSVTEAKTLFDTNLFGMLCTIQAVLPHMREQRSG 125
Query: 122 KVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWKG 181
++V I S + + Y ASK A+ +++ L+ E+++ GI+V V P T+
Sbjct: 126 RIVNISSVLGFLPAPYMALYSASKHAVEGLSETLDHEVRQFGIRVALVEPSFTKTNMDLN 185
Query: 182 AKLRGALSPEY 192
A + P+Y
Sbjct: 186 APQTASKIPDY 196
>dbj|BAB07807.1| (AB032242) serine dehydrogenase [Agrobacterium tumefaciens]
Length = 249
Score = 74.5 bits (180), Expect = 1e-12
Identities = 64/225 (28%), Positives = 100/225 (44%), Gaps = 12/225 (5%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALK----ELGIKY--IVVDLSTYEGIS 62
+L+TGA+ G GQ A+ ++ G++VIG GR + L+ ELG + + D++ E
Sbjct: 5 ILITGATSGFGQATAQRFVKEGWKVIGTGRRAERLEALSAELGSAFHGVAFDITDEEATK 64
Query: 63 KVRESLKG---EIDVLINNAGFGL-VKPLLEHSWEELEGMFKVNAIAPVILTKELL-DFI 117
K L +ID+L+NNAG L P + ++ + M N + +T LL I
Sbjct: 65 KALAGLPDGFRDIDILVNNAGLALGTAPAPQVPLKDWQTMVDTNITGLLNVTHHLLPTLI 124
Query: 118 PEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATD 177
G V+ + S A+H L YG +K L + L +L +G++V + P T+
Sbjct: 125 ERKGIVINLSSVAAHYPYLGGNVYGGTKAFLRQFSLGLRSDLHGKGVRVTSIEPGMCETE 184
Query: 178 FWKGAKLRGALSPEYVARKIVNAIESDKRELFIPWYLKLAKFFEI 222
F + G K VN I +D I W K I
Sbjct: 185 FTL-VRTGGNQEASDNLYKGVNPITADDIANTIHWVASQPKHINI 228
>gb|AAD03695.1| (AF090422) surface sperm protein P26h [Mesocricetus auratus]
Length = 244
Score = 74.5 bits (180), Expect = 1e-12
Identities = 59/183 (32%), Positives = 91/183 (49%), Gaps = 11/183 (6%)
Query: 7 MRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-----GIKYIVVDLSTYEGI 61
+R L+TGA GIG+ AK L G +V+ V + L L GI+ + VDL +E
Sbjct: 8 LRALVTGAGRGIGRGTAKALHASGAKVVAVSLINEDLVSLAKECPGIEPVCVDLGDWEAT 67
Query: 62 SKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL--DFIPE 119
K + G +D+L+NNA LV+P ++ + E + F VN + V+ +++ I
Sbjct: 68 EKALGRI-GPVDLLVNNAAVALVQPFIQSTKEVFDRSFNVN-VRSVLQVSQMVAKGMINR 125
Query: 120 G--GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATD 177
G G +V I S ++V L Y ++K A+ + K + EL I+V V P V TD
Sbjct: 126 GVAGSIVNISSMVAYVTFPGLATYSSTKGAITMLTKAMAMELGPYKIRVNSVNPTVVLTD 185
Query: 178 FWK 180
K
Sbjct: 186 MGK 188
>gb|AAC63265.1| (AF061743) retinal short-chain dehydrogenase/reductase retSDR1 [Mus
musculus] >gi|5901773|gb|AAD55403.1| (AF179241) retinal
short-chain dehydrogenase/reductase 1 [Mus musculus]
Length = 302
Score = 74.5 bits (180), Expect = 1e-12
Identities = 69/233 (29%), Positives = 113/233 (47%), Gaps = 29/233 (12%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGV-GRNEKALKE-------LGIK--YIVVDLSTY 58
VL+TG GIG+ LA+E RG I + GR EK LKE +G + Y + D+
Sbjct: 41 VLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNR 100
Query: 59 EGISKVRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD 115
E + ++ ++++ G+I +L+NNA K L++ + L VN + TK L
Sbjct: 101 EEVYQMAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLP 160
Query: 116 FIPE--GGKVVFIISGASHVYTLD-LPG---YGASKV-ALHYMAKVLEEELKERGIKVLR 168
+ E G +V + S V L +PG Y SK A +M + L G+
Sbjct: 161 RMLELQNGHIVCLNS----VLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATT 216
Query: 169 VYPKQVATDFWKGAKLR-----GALSPEYVARKIVNAIESDKRELFIPWYLKL 216
V P +T+ ++G ++R L PE VAR+ V+A++ ++ L +PW + +
Sbjct: 217 VLPFHTSTEMFQGMRVRLPNLFPPLKPETVARRTVDAVQQNQALLLLPWTMNI 269
>pir||C83416 probable short-chain dehydrogenase PA1827 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947813|gb|AAG05216.1|AE004609_3 (AE004609) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 253
Score = 74.5 bits (180), Expect = 1e-12
Identities = 64/202 (31%), Positives = 100/202 (48%), Gaps = 24/202 (11%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-----GIKYIVVDLSTYEGISKV 64
L+TG S GIG +A+ L ++GY + V R+ + L+ G+ ++ DLS E + V
Sbjct: 12 LVTGGSSGIGLAIARRLRQQGYRIALVARDSQRLQRAAAELGGVPWMAADLSRREAVEAV 71
Query: 65 R----ESLKGEIDVLINNAGF----GLVKPLLEHSWEELEGMFKVNAIAPVILTKELL-D 115
++ +G +DVL+NNAGF PL E + E + + N + +++ +L
Sbjct: 72 AAWVGDTFQG-LDVLVNNAGFTRKIAATTPLAE-AEREWDALLDGNLKSAFLMSLAVLPH 129
Query: 116 FIPEGGKVVFI--ISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQ 173
F EGG+++ I I+ + + GY A+K LH L EL RGI V V P
Sbjct: 130 FAEEGGRIIHIGSIAAQTGSGSPGALGYAAAKAGLHGFGVALARELGSRGITVNSVAPGY 189
Query: 174 VA-TDFWKGAKLRGALSPEYVA 194
+A T F+ G L P+ VA
Sbjct: 190 IADTRFFP-----GGLDPQRVA 206
>pir||E83135 probable dehydrogenase PA4079 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950278|gb|AAG07466.1|AE004824_1
(AE004824) probable dehydrogenase [Pseudomonas
aeruginosa]
Length = 229
Score = 74.1 bits (179), Expect = 1e-12
Identities = 70/229 (30%), Positives = 108/229 (46%), Gaps = 28/229 (12%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNE------KALKELG---IKYIVVDLSTYE 59
VL+ GAS GIG LA ++RG +V V R +AL E ++ + DL+ ++
Sbjct: 4 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHD 63
Query: 60 GISKVRESL-KGEIDVLINNAGF--GLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
++ E L + ID LI NAG + + E E+ +F NAIAP+ L + L
Sbjct: 64 CAERIGEMLGERRIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARALSGR 123
Query: 117 IPEGGKVVFIISGASHV---YTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQ 173
+ GG V F+ S + + + +P YGASK AL+ + + E E +E +L ++P
Sbjct: 124 VSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLLLHPGW 183
Query: 174 VATDFWKGAKLRGALSPEYVARKIVNAIES----------DKRELFIPW 212
V T+ + LS E A +V A+E D R +PW
Sbjct: 184 VRTEMGGDS---APLSVEESAAGLVAAVEDAAGVNACRFVDYRNQPLPW 229
>sp|P14802|YOXD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN RTP-PELB INTERGENIC REGION (ORF238)
>gi|7427655|pir||D69930 probable
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100) yoxD - Bacillus subtilis
>gi|2634244|emb|CAB13743.1| (Z99114) similar to
3-oxoacyl- acyl-carrier protein reductase [Bacillus
subtilis]
Length = 238
Score = 73.7 bits (178), Expect = 2e-12
Identities = 63/226 (27%), Positives = 107/226 (46%), Gaps = 21/226 (9%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNE-------KALKELGIK--YI 51
M L + L+TG GIG+ A L + G + +GR + +K LG+K +
Sbjct: 1 MQSLQHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVEKVAEEVKALGVKAAFA 60
Query: 52 VVDLS----TYEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPV 107
D+ + +++V+E L G+ID+LINNAG L+ S +E E + +VN +
Sbjct: 61 AADVKDADQVNQAVAQVKEQL-GDIDILINNAGISKFGGFLDLSADEWENIIQVNLMGVY 119
Query: 108 ILTKELLDFIPE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIK 165
+T+ +L + E G ++ I S A Y ASK A+ + + L +E+++ I+
Sbjct: 120 HVTRAVLPEMIERKAGDIINISSTAGQRGAAVTSAYSASKFAVLGLTESLMQEVRKHNIR 179
Query: 166 VLRVYPKQVATDFWKGAKL-----RGALSPEYVARKIVNAIESDKR 206
V + P VA+D L + PE +A +V ++ D R
Sbjct: 180 VSALTPSTVASDMSIELNLTDGNPEKVMQPEDLAEYMVAQLKLDPR 225
>gi|6320089 Ydl114wp [Saccharomyces cerevisiae] >gi|2131337|pir||S67657
hypothetical protein YDL114w - yeast (Saccharomyces
cerevisiae) >gi|1431166|emb|CAA98682.1| (Z74162) ORF
YDL114w [Saccharomyces cerevisiae]
Length = 308
Score = 73.7 bits (178), Expect = 2e-12
Identities = 69/236 (29%), Positives = 116/236 (48%), Gaps = 26/236 (11%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNE----KALKELGIKYIVVDLSTYEGISKVR 65
L+TG S G+G ELAKEL RR +VI ++ I Y D+++ + I ++
Sbjct: 42 LITGGSSGLGFELAKELSRRINKVIVADIQSFPTFAQVEYNNIFYYQCDITSLDEIKNLK 101
Query: 66 ESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAI-APVILTKELLDFIP-EG 120
++++ G I+++INNAG +K L + +E+E + +N I A I++ D I
Sbjct: 102 KAIERDHGNINIIINNAGVAHIKKLEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNRE 161
Query: 121 GKVVFIISGASHVYTLDLPGYGASKVAL---------HYMAKVLEEELKERGIKVLRVYP 171
G ++ I S + L YGASK A+ H+ + L E + GIK L V P
Sbjct: 162 GFIINIASVLGELTPARLTSYGASKGAMIGFHKCMSRHF--RSLSTECNKTGIKTLLVCP 219
Query: 172 KQVATDFW-----KGAKLRGALSPEYVARKIVNAIESDK-RELFIPWYLKLAKFFE 221
++ T+ + L + P +A I++A+E + + L P+Y+ L FF+
Sbjct: 220 GKIKTNMFIDVPTPSKLLAPDIIPSQLALAIISAMEHNHLQTLNAPYYVNLVPFFK 275
>sp|O57314|DHBX_ANAPL PUTATIVE STEROID DEHYDROGENASE SPM2 >gi|2665393|dbj|BAA23765.1|
(AB009304) steroid dehydrogenase [Anas platyrhynchos]
Length = 312
Score = 73.7 bits (178), Expect = 2e-12
Identities = 63/192 (32%), Positives = 98/192 (50%), Gaps = 18/192 (9%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG----------IKYIVVDLSTYE 59
++TGA+ GIG+ AKEL +RG +V + R+++ L ++ K IV D E
Sbjct: 52 VVTGATDGIGKAYAKELAKRGMKVALISRSKEKLDQVAGEITEQYGVETKVIVADFGERE 111
Query: 60 GI-SKVRESLKG-EIDVLINNAGFGLVKPL----LEHSWEELEGMFKVNAIAPVILTKEL 113
I ++R L+G EI VL+NN G P + + ++ M +N ++ +T+ +
Sbjct: 112 DIYDRIRAGLEGLEIGVLVNNVGISYSYPEYFIDVPDLDKTIDKMININIMSVCKMTRLV 171
Query: 114 LDFIPEGGK-VVFIISGASHVY-TLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYP 171
L + E K V+ IS A+ +Y T L Y ASK + Y ++ L E K +GI V V P
Sbjct: 172 LPGMLERSKGVILNISSAAGMYPTPLLTLYSASKAFVDYFSRGLHAEYKSKGIIVQSVMP 231
Query: 172 KQVATDFWKGAK 183
VAT K +K
Sbjct: 232 YYVATKMSKISK 243
>gb|AAC63264.1| (AF061742) retinal short-chain dehydrogenase/reductase retSDR1 [Bos
taurus]
Length = 302
Score = 73.7 bits (178), Expect = 2e-12
Identities = 71/235 (30%), Positives = 112/235 (47%), Gaps = 31/235 (13%)
Query: 4 LNYMRVLLTGASGGIGQELAKELIRRG-YEVIGVGRNEKALKE-------LGIK--YIVV 53
L+ VL+TG GIG++LA+E RG +++ GR EK LKE +G + Y +
Sbjct: 36 LSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFIC 95
Query: 54 DL----STYEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVIL 109
D+ Y+ VRE + G+I +L+NNA K L++ + L +N +
Sbjct: 96 DVGNREEVYQTAKAVREKV-GDITILVNNAAVVHGKSLMDSDDDALPKSQHINTLGQFWT 154
Query: 110 TKELLDFIPE--GGKVVFIISGASHVYTLD-LPG---YGASKV-ALHYMAKVLEEELKER 162
TK L + E G +V + S V L +PG Y SK A +M + L
Sbjct: 155 TKAFLPRMLELQNGHIVCLNS----VLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCP 210
Query: 163 GIKVLRVYPKQVATDFWKGAKLR-----GALSPEYVARKIVNAIESDKRELFIPW 212
G+ V P +T+ ++G ++R L PE VAR+ V A++ ++ L +PW
Sbjct: 211 GVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPW 265
>pir||T35808 probable oxidoreductase - Streptomyces coelicolor
>gi|4467243|emb|CAB37568.1| (AL035569) putative
oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 232
Score = 73.7 bits (178), Expect = 2e-12
Identities = 61/178 (34%), Positives = 87/178 (48%), Gaps = 14/178 (7%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-----GIKYIVVDLSTYEGISKV 64
++TGA GIG +A+ L RG EV+ R+ KEL G K +V DLS +S
Sbjct: 8 VITGAGSGIGAAVARRLHERGDEVVLHARDAGRAKELAAALPGAKTLVGDLSDPGKLSWA 67
Query: 65 --RESLKGEIDVLINNAG---FGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE 119
+SL +D L++ AG G V L +W VN +AP LT+ LL +
Sbjct: 68 LSHQSLPDRVDSLLHIAGVVDLGPVGDLTPKTWLH---QLSVNLVAPAELTRLLLPQLRV 124
Query: 120 G-GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
G+V+F+ SG+ YGASK L +A L +E G++V VYP + A+
Sbjct: 125 AQGQVIFVNSGSGLNAHAGWAAYGASKHGLKALADALRQEEHANGVRVTSVYPGRTAS 182
>pir||D75336 oxidoreductase, short-chain dehydrogenase/reductase family -
Deinococcus radiodurans (strain R1)
>gi|6459722|gb|AAF11489.1|AE002032_7 (AE002032)
oxidoreductase, short-chain dehydrogenase/reductase
family [Deinococcus radiodurans]
Length = 283
Score = 73.7 bits (178), Expect = 2e-12
Identities = 72/220 (32%), Positives = 105/220 (47%), Gaps = 24/220 (10%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-------GIKYIVVDLSTYEGI 61
V+LTGAS GIG A+EL +GY ++ R L++L G + I V +
Sbjct: 34 VVLTGASSGIGLATAEELAAQGYALVLAARRADTLRDLARRLDPSGSRVIAVPTDVTDDA 93
Query: 62 SKVRESLK------GEIDVLINNAGFGLVKPLLEHSWEELEGM--FKVNAIAPVILTKEL 113
S+ R L+ G +DVLINNAG + K W++ + + +VN AP+ LT+ +
Sbjct: 94 SR-RSLLQFAHDHFGRVDVLINNAGVTVEKGWW---WDDPDPLRVVRVNLEAPIELTRLV 149
Query: 114 L-DFIPEG-GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYP 171
L D G G +V I S A T + Y ASK + + L EL GI V V P
Sbjct: 150 LPDMQARGNGHIVNIGSVAGRAATNGM--YSASKFGIRGFSHGLRRELLGSGIDVSLVAP 207
Query: 172 KQVATDFWKGAKLRGALSPEYVARKIVNAIESDKRELFIP 211
V ++ AKL PE VAR + + + + E+ +P
Sbjct: 208 GFVQSEMTAKAKL-PMPGPEVVARAVADVLRRPQPEVIVP 246
>pir||H81140 oxidoreductase, short-chain dehydrogenase/reductase family NMB0924
[imported] - Neisseria meningitidis (group B strain
MD58) >gi|7226163|gb|AAF41332.1| (AE002444)
oxidoreductase, short-chain dehydrogenase/reductase
family [Neisseria meningitidis MC58]
Length = 273
Score = 73.7 bits (178), Expect = 2e-12
Identities = 56/192 (29%), Positives = 91/192 (47%), Gaps = 12/192 (6%)
Query: 7 MRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALK----ELGIKY--IVVDLSTYEG 60
M VL+TGAS G G+ + + + GY VIG R L+ ELG + + +D+S E
Sbjct: 1 MAVLITGASAGFGEAMCRAFVGAGYRVIGAARRADRLQALADELGALFYPLEMDVSRRES 60
Query: 61 ISKVRESLKGE---IDVLINNAGFGLVKPLLEHS-WEELEGMFKVNAIAPVILTKELLDF 116
+ + E ID LINNAG L + + +E+ E M + N + LT+++L
Sbjct: 61 VENALNGIPDEFSDIDCLINNAGLALGLDTADKADFEDWETMIQTNVLGLTFLTRKILPQ 120
Query: 117 IPE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQV 174
+ E GG V+ + S A + YGA+K + + L EL ++ I+V + P
Sbjct: 121 MVERGGGYVMNLGSIAGNYAYAGSNVYGATKAFVRQFSLNLRAELADKNIRVTNIEPGLC 180
Query: 175 ATDFWKGAKLRG 186
+ + +G
Sbjct: 181 GNTEFSNVRFKG 192
>pir||D81878 probable oxidoreductase NMA1120 [imported] - Neisseria meningitidis
(group A strain Z2491) >gi|7379814|emb|CAB84382.1|
(AL162755) putative oxidoreductase [Neisseria
meningitidis Z2491]
Length = 273
Score = 73.7 bits (178), Expect = 2e-12
Identities = 56/192 (29%), Positives = 91/192 (47%), Gaps = 12/192 (6%)
Query: 7 MRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALK----ELGIKY--IVVDLSTYEG 60
M VL+TGAS G G+ + + + GY VIG R L+ ELG + + +D+S E
Sbjct: 1 MAVLITGASAGFGEAMCRAFVGAGYRVIGAARRADRLQALADELGALFYPLEMDVSRRES 60
Query: 61 ISKVRESLKGE---IDVLINNAGFGLVKPLLEHS-WEELEGMFKVNAIAPVILTKELLDF 116
+ + E ID LINNAG L + + +E+ E M + N + LT+++L
Sbjct: 61 VENALNGIPDEFSDIDCLINNAGLALGLDTADKADFEDWETMIQTNVLGLTFLTRKILPQ 120
Query: 117 IPE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQV 174
+ E GG V+ + S A + YGA+K + + L EL ++ I+V + P
Sbjct: 121 MVERGGGYVMNLGSIAGNYAYAGSNVYGATKAFVRQFSLNLRAELADKNIRVTNIEPGLC 180
Query: 175 ATDFWKGAKLRG 186
+ + +G
Sbjct: 181 GNTEFSNVRFKG 192
>pir||F83479 probable short-chain dehydrogenase PA1330 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947269|gb|AAG04719.1|AE004562_6 (AE004562) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 259
Score = 73.7 bits (178), Expect = 2e-12
Identities = 60/180 (33%), Positives = 91/180 (50%), Gaps = 9/180 (5%)
Query: 8 RVLLTGASGGIGQELAKELIRRGYEVI----GVGRNEKALKELGIKYIVVDLSTYE-GIS 62
R+L+TGA G G+E+A L RG+ I G G+ +E G + + + + T + ++
Sbjct: 5 RILVTGAGSGFGREVALRLAARGHRTIAGVRGAGQAADLREEAGRRGVPLRVETLDITVA 64
Query: 63 KVRE-SLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE-- 119
RE + + +IDVL+NNAG E E + +F+ N A + LT+ + + E
Sbjct: 65 ADRERAWEWDIDVLLNNAGSAEAGASAEIPLELVRALFETNVFANLELTQGFVRRMVEQK 124
Query: 120 -GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDF 178
GGKV+F+ S A + Y ASK AL A+ L ELK GI+V + P T F
Sbjct: 125 RGGKVLFVSSIAGLITGPYTGPYCASKHALEAFAEALHAELKPFGIQVGTINPGPYQTGF 184
>pir||F83229 probable short chain dehydrogenase PA3330 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949461|gb|AAG06718.1|AE004755_5 (AE004755) probable
short chain dehydrogenase [Pseudomonas aeruginosa]
Length = 304
Score = 73.7 bits (178), Expect = 2e-12
Identities = 57/185 (30%), Positives = 90/185 (47%), Gaps = 14/185 (7%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVI-GVGRNE------KALKELGIKYIVVDLSTYEGI 61
VL+TGAS G+G+E A L +G++VI GV R E A I +++D++ E I
Sbjct: 15 VLITGASSGLGRETALHLAEQGFQVIAGVRRQEDGERLANACPSGRISTLLIDVTDEESI 74
Query: 62 SKVRESLKGEID-----VLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
+ + ++ L+NNAG + PL S + L +VN I + +T+ +L
Sbjct: 75 GRAAAQVAEKVGDTGLWGLVNNAGICISAPLECVSSDLLRRQLEVNLIGQLAVTRAILPL 134
Query: 117 IPEGG--KVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQV 174
+ GG ++V + SG V L Y A++ A ++ L EL GI+V V P +
Sbjct: 135 LRRGGAARLVNVTSGLGSVAIPYLGAYSAAQFAKEGVSDALRRELAPMGIQVSVVSPGAI 194
Query: 175 ATDFW 179
T W
Sbjct: 195 WTPIW 199
>gi|4759084 short-chain dehydrogenase/reductase 1 [Homo sapiens]
>gi|3450828|gb|AAC63263.1| (AF061741) retinal
short-chain dehydrogenase/reductase retSDR1 [Homo
sapiens] >gi|5901767|gb|AAD55402.1| (AF179237)
short-chain dehydrogenase/reductase 1 [Homo sapiens]
Length = 302
Score = 73.0 bits (176), Expect = 3e-12
Identities = 71/235 (30%), Positives = 112/235 (47%), Gaps = 31/235 (13%)
Query: 4 LNYMRVLLTGASGGIGQELAKELIRRG-YEVIGVGRNEKALKE-------LGIK--YIVV 53
L+ VL+TG GIG++LA+E RG +++ GR EK LKE +G + Y +
Sbjct: 36 LSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFIC 95
Query: 54 DL----STYEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVIL 109
D+ Y+ VRE + G+I +L+NNA K L++ + L +N +
Sbjct: 96 DVGNREEVYQTAKAVREKV-GDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWT 154
Query: 110 TKELLDFIPE--GGKVVFIISGASHVYTLD-LPG---YGASKV-ALHYMAKVLEEELKER 162
TK L + E G +V + S V L +PG Y SK A +M + L
Sbjct: 155 TKAFLPRMLELQNGHIVCLNS----VLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCP 210
Query: 163 GIKVLRVYPKQVATDFWKGAKLR-----GALSPEYVARKIVNAIESDKRELFIPW 212
G+ V P +T+ ++G ++R L PE VAR+ V A++ ++ L +PW
Sbjct: 211 GVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPW 265
>gb|AAF53953.1| (AE003669) CG9265 gene product [Drosophila melanogaster]
Length = 399
Score = 72.6 bits (175), Expect = 4e-12
Identities = 73/238 (30%), Positives = 112/238 (46%), Gaps = 20/238 (8%)
Query: 4 LNYMRVLLTGASGGIGQELAKELIRRGYEVI-------GVGRNEKALKELG--IKYIVVD 54
LN L+TG G+G+ LA+ L + G +V+ G+ + ++E G K VVD
Sbjct: 84 LNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDINKKGIAETVQIVEEAGGYCKGYVVD 143
Query: 55 LSTYEGISKVRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTK 111
+S E + K + ++ G+I +LINNAG LL+ +E F VN +A TK
Sbjct: 144 ISKKEEVYKAADVIRDEVGDITLLINNAGVVSGLHLLDTPDHLIERSFNVNVMAHFWTTK 203
Query: 112 ELLDFIPEG--GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERG---IKV 166
L + E G + I S A HV L Y ASK A + L EL+ G I+
Sbjct: 204 AFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEVLGHTNIRT 263
Query: 167 LRVYPKQV-ATDFWKGAKLR--GALSPEYVARKIVNAIESDKRELFIPWYLKLAKFFE 221
+ P + AT + R L+P VA +++ AI +++ IP +LK+ F+
Sbjct: 264 TCICPFFIQATGMFDDVNARWVPTLNPNDVADRVIAAIRKNEKLAVIPGFLKVLLSFK 321
>pir||T49258 dehydrogenase-like protein - Arabidopsis thaliana
>gi|7799005|emb|CAB90944.1| (AL355775)
dehydrogenase-like protein [Arabidopsis thaliana]
Length = 288
Score = 72.6 bits (175), Expect = 4e-12
Identities = 65/209 (31%), Positives = 104/209 (49%), Gaps = 34/209 (16%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL----------GIKY------IV 52
VL+TGAS GIG+E+ +L + G ++I V R L L GI+ +
Sbjct: 31 VLVTGASSGIGREICLDLGKAGCKIIAVARRVDRLNSLCSEINSSSSTGIQAAALKLDVT 90
Query: 53 VDLSTYEGISKVRESLKGEIDVLINNAGF-GLVKPLLEHSWEELEGMFKVNAIAPVILTK 111
D +T + + + + G+ID LINNAG G VK L+ S EE + +FK N P +++K
Sbjct: 91 SDAATIQKVVQGAWGIFGKIDALINNAGIRGNVKSSLDLSKEEWDNVFKTNLTGPWLVSK 150
Query: 112 ELLDFIPE---GGKVVFI--ISGASHVYTLDLPG---YGASKVALHYMAKVLEEELKERG 163
+ + + GG V+ I I+G + LPG Y SK+ + M+K++ EL G
Sbjct: 151 YVCVLMRDAKLGGSVINISSIAGIRGI----LPGALAYACSKIGVDTMSKMMAVEL---G 203
Query: 164 IKVLRVYPKQVATDFWKGAKLRGALSPEY 192
+ +RV +A +K +G + E+
Sbjct: 204 VHKIRV--NSIAPGIFKSEITQGLMQKEW 230
>pir||G82239 oxidoreductase, short-chain dehydrogenase/reductase family VC1119
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9655590|gb|AAF94278.1| (AE004192) oxidoreductase,
short-chain dehydrogenase/reductase family [Vibrio
cholerae]
Length = 241
Score = 72.6 bits (175), Expect = 4e-12
Identities = 48/173 (27%), Positives = 87/173 (49%), Gaps = 5/173 (2%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKY-----IVVDLSTYEGISK 63
V +TGA+ GIG++LA + ++G++VI GRN+ L L +Y + D++ + G
Sbjct: 4 VFITGATSGIGKQLALDYAKQGWQVIACGRNQSVLDSLHTQYANIFPLAFDVTDHPGTKA 63
Query: 64 VRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEGGKV 123
L + ++ I NAG + + +F +N + + + + + G +V
Sbjct: 64 ALAQLPCQPELWILNAGDCEYIDDGKMDVTLMARVFNINVLGVAAVIEGIQPHLSCGHRV 123
Query: 124 VFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
+ S AS + YGASK A+ Y+A+ L+ + + GI+V ++P VAT
Sbjct: 124 AIVGSIASELALPRAEAYGASKAAVAYLARTLQLDWRPLGIEVTTIFPGFVAT 176
>pir||H83046 probable short-chain dehydrogenase PA4786 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951052|gb|AAG08172.1|AE004892_3 (AE004892) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 451
Score = 72.6 bits (175), Expect = 4e-12
Identities = 55/177 (31%), Positives = 90/177 (50%), Gaps = 8/177 (4%)
Query: 8 RVLLTGASGGIGQELAKELIRRGYEVI--GVGRNEKALK----ELGIKYIVVDLSTYEGI 61
R L+TGA+ GIG +A+ L R G EV+ V +AL+ LG + + +D+ +
Sbjct: 216 RALVTGAARGIGAAIAETLARDGAEVVLLDVPPAREALEGLAARLGGRAVALDICAADAG 275
Query: 62 SKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD--FIPE 119
++ E+L +D++++NAG K L + S + + VN AP +LT+ LLD + +
Sbjct: 276 QQLVEALPEGVDIVVHNAGITRDKTLAKMSSDFWNSVINVNLNAPQVLTQALLDGGKLHD 335
Query: 120 GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
G+VV + S + L Y SK L +A+ L +RGI + V P + T
Sbjct: 336 NGRVVLLASISGIAGNLGQSNYAVSKAGLIGLAQAWAPALGKRGITINAVAPGFIET 392
>gb|AAD00504.1| (U81186) smooth muscle-specific 17beta-hydroxysteroid dehydrogenase
type 3 [Rattus norvegicus]
Length = 291
Score = 72.2 bits (174), Expect = 5e-12
Identities = 60/193 (31%), Positives = 98/193 (50%), Gaps = 20/193 (10%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG----------IKYIVVDLSTYE 59
++TG + GIG+ A+EL +RG +++ + R++ LKE+ + I VD S +
Sbjct: 54 VVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLKEVSNNIKEKFNVETRTIAVDFSLDD 113
Query: 60 GISKVRESLKG-EIDVLINNAGFGLVKPLLEHSWEELEGMFK----VNAIAPVILTKELL 114
K++ L G EI VL+NN G P +L+ K +N ++ +T+ +L
Sbjct: 114 IYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSICKVTRLVL 173
Query: 115 DFIPEGGK-VVFIISGASHVYTLD-LPGYGASKVALHYMAKVLEEELKERGIKVLRVYPK 172
+ E K V+ IS AS + + L Y A+K + + ++ L EE K +GI V V P
Sbjct: 174 PGMVERSKGVILNISSASGMLPVPLLTVYSATKAFVDFFSQCLHEEYKSKGIFVQSVLPF 233
Query: 173 QVATDFWKGAKLR 185
V+T K AK+R
Sbjct: 234 FVST---KLAKIR 243
>pir||H75014 3-oxoacyl-[acyl-carrier-protein] reductase PAB1085 - Pyrococcus
abyssi (strain Orsay) >gi|5459072|emb|CAB50558.1|
(AJ248288) 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE
[Pyrococcus abyssi]
Length = 240
Score = 71.4 bits (172), Expect = 9e-12
Identities = 74/221 (33%), Positives = 108/221 (48%), Gaps = 31/221 (14%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVI--------GVGRNEKALKELGIKYIVV--DLSTYE 59
L+TGAS GIG+ +A EL +RG V+ + E+ ++ G++ ++V D+S E
Sbjct: 9 LITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTEELCRQYGVETLLVKADVSNRE 68
Query: 60 GISKVRESLK------GEIDVLINNAG-FGLVKPLLEHSWEELEGMFKVNAIAPVILTKE 112
+VRE +K G ID+LINNAG G K LE + EE + + VN I+T+E
Sbjct: 69 ---EVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAFIVTQE 125
Query: 113 LLDFIPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPK 172
+L ++ + GK+V I S A P Y ASK L + L L I V V P
Sbjct: 126 VLRYMKK-GKIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLARHLAP-NILVNAVAPG 183
Query: 173 QVATD--------FWKGAKLRGALS-PEYVARKIVNAIESD 204
V TD K L G ++ P VA ++ +E+D
Sbjct: 184 PVDTDMLSSEMKEMLKKLSLTGDIAKPSEVAHAVIFLLEND 224
>pir||T37016 probable oxidoreductase - Streptomyces coelicolor
>gi|5738859|emb|CAB52931.1| (AL109949) putative
oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 230
Score = 71.4 bits (172), Expect = 9e-12
Identities = 54/201 (26%), Positives = 90/201 (43%), Gaps = 3/201 (1%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKYIVVDLSTYEGISKVRESLK 69
++TGA+ G G+ LA +L+ RG +V G R + + G+ +++D+ T E + +
Sbjct: 9 VVTGANRGFGRHLAAQLVERGAKVYGAARRPETVDVPGVIPLLLDV-TDEASIREATRVA 67
Query: 70 GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPE--GGKVVFII 127
+ +LINNAG LL E+ + N P+ T+ I GG V+ ++
Sbjct: 68 SDTTLLINNAGISTGATLLGGDMTEVRRDMETNYFGPLATTRSFAPVIEANGGGAVLNVL 127
Query: 128 SGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWKGAKLRGA 187
S S + L Y ASK A + +EL RGI V ++ + TD
Sbjct: 128 SALSWFHPAGLGSYAASKAAAWALTGATRDELAPRGIAVSALHVGYMDTDMAADVPADQK 187
Query: 188 LSPEYVARKIVNAIESDKREL 208
+ VA + + IE+ E+
Sbjct: 188 VDAGEVAAQALYGIETGLPEV 208
>emb|CAB58279.1| (AL121849) putative oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 245
Score = 71.4 bits (172), Expect = 9e-12
Identities = 68/221 (30%), Positives = 104/221 (46%), Gaps = 29/221 (13%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIK---------YIVVDLSTYE 59
V +TGASGGIG+ A L RG +V+ R + L +L ++ +I D++ E
Sbjct: 9 VAITGASGGIGEASALLLAERGAKVVLGARRPERLADLALRIGRSGGEAAWIRTDVTRRE 68
Query: 60 GISKV----RESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD 115
++ + RE G +DVL+ NAG GL+ PL E E+ E M VN + E L
Sbjct: 69 DVAALVALARERF-GRLDVLVGNAGVGLISPLDELRVEDWERMIDVNLKGVLYGIAEALP 127
Query: 116 FIPE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQ 173
E G V I+S A + + Y +K A+ +++ L +E + ++V V P
Sbjct: 128 VFREQGSGHFVNIVSTAGLRISPLMSVYAGTKNAVRTVSEGLRQEAGD-SLRVTVVSPGF 186
Query: 174 VATDFWKG------------AKLRGALSPEYVARKIVNAIE 202
V TDF G + R A+ P+ VAR + A+E
Sbjct: 187 VHTDFADGIPDAGARAQILDTRDRVAIPPQAVARAVAFAVE 227
>sp|O85141|FABG_SALTY 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|3282804|gb|AAC38650.1| (AF044668)
3-oxoacyl-acyl carrier protein reductase [Salmonella
typhimurium]
Length = 244
Score = 71.0 bits (171), Expect = 1e-11
Identities = 52/179 (29%), Positives = 87/179 (48%), Gaps = 11/179 (6%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL---------GIKYIVVDLSTYEG 60
L+TGAS GIG+ +A+ L+ RG +VIG +E K + G+ V D ++ E
Sbjct: 9 LVTGASRGIGRAIAETLVARGAKVIGTATSENGAKNISDYLGANGKGLMLNVTDPASIES 68
Query: 61 ISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEG 120
+ + + GE+D+L+NNAG L+ +E + + N + L+K ++ + +
Sbjct: 69 VLENIRAEFGEVDILVNNAGITRDNLLMRMKDDEWNDIIETNLSSVFRLSKAVMRAMMKK 128
Query: 121 --GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATD 177
G+++ I S + Y A+K L +K L E+ RGI V V P + TD
Sbjct: 129 RCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRGITVNVVAPGFIETD 187
>pir||T36060 probable oxidoreductase - Streptomyces coelicolor
>gi|3928730|emb|CAA22226.1| (AL034355) putative
oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 585
Score = 71.0 bits (171), Expect = 1e-11
Identities = 58/205 (28%), Positives = 97/205 (47%), Gaps = 18/205 (8%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRN-EKALKELGIKYIV---------VDLSTY 58
VL+TGA GIG+ A G V+ V R+ E A + + ++ VD+S
Sbjct: 320 VLVTGAGSGIGRATAFAFAEAGARVVAVDRDAEAAARTAELSRLIGARAAWAEAVDVSDE 379
Query: 59 EGISKVRESLKGE---IDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPV----ILTK 111
+ + K+ + E +DVL+NNAG GL + + E+ + + VN + + +
Sbjct: 380 QAMEKLAARVAAEYGVVDVLVNNAGIGLSGSFFDTTPEDWKKVLDVNLWGVIHGCRLFGR 439
Query: 112 ELLDFIPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYP 171
++ + +GG +V S A+ + LP YG SK A+ +++ L EL +RGI V + P
Sbjct: 440 QMAER-GQGGHIVNTASAAAFQPSRVLPAYGTSKAAVLMLSECLRAELADRGIGVTAICP 498
Query: 172 KQVATDFWKGAKLRGALSPEYVARK 196
V T+ A G + E R+
Sbjct: 499 GLVNTNITSTAHFAGVDAEEEKRRQ 523
>gb|AAC95219.1| (AC004561) putative tropinone reductase [Arabidopsis thaliana]
Length = 268
Score = 71.0 bits (171), Expect = 1e-11
Identities = 66/232 (28%), Positives = 108/232 (46%), Gaps = 32/232 (13%)
Query: 4 LNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKE---------LGIKYIVVD 54
L M L+TG S G+G+ + +EL G V R+E L+E + V D
Sbjct: 16 LEGMTALVTGGSKGLGEAVVEELAMLGARVHTCARDETQLQERLREWQAKGFEVTTSVCD 75
Query: 55 LSTYEGISKVRESL----KGEIDVLINNAGFGLVKPLLEHSWEE--------LEGMFKVN 102
+S+ E K+ E++ +G++++L+NNAG G++KP E++ E+ LE F ++
Sbjct: 76 VSSREQREKLMETVSSVFQGKLNILVNNAGTGIIKPSTEYTAEDYSFLMATNLESAFHLS 135
Query: 103 AIAPVILTKELLDFIPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKER 162
IA +L G +VF+ S A V+T YGASK A++ + + L E
Sbjct: 136 QIAHPLLKAS------GSGSIVFMSSVAGLVHT-GASIYGASKGAMNQLGRSLACEWASD 188
Query: 163 GIKVLRVYPKQVATD----FWKGAKLRGALSPEYVARKIVNAIESDKRELFI 210
I+V V P + T + KLR A+ + ++ A E F+
Sbjct: 189 NIRVNSVCPWVITTPLTSFIFSDEKLRKAVEDKTPMGRVGEANEVSSLVAFL 240
>pir||F81902 probable oxidoreductase NMA1336 [imported] - Neisseria meningitidis
(group A strain Z2491) >gi|7380008|emb|CAB84586.1|
(AL162755) putative oxidoreductase [Neisseria
meningitidis Z2491]
Length = 256
Score = 71.0 bits (171), Expect = 1e-11
Identities = 52/182 (28%), Positives = 92/182 (49%), Gaps = 19/182 (10%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-------------G 47
M L+ +L+TGAS G+G+++AK G VI V R++K L+++
Sbjct: 18 MATLSDKTILITGASQGLGEQVAKAYAAAGATVILVARHQKKLEKVYDAIVEARHPEPFA 77
Query: 48 IKYIVVDLSTYE---GISKVRESLKGEIDVLINNAG-FGLVKPLLEHSWEELEGMFKVNA 103
I++ ++ E + + E+ +G++D +++ AG F + PL + E +++N
Sbjct: 78 IRFDLMSAEEKEFNQFAATIAEATQGKLDGIVHCAGYFYALSPLDFQTVAEWVNQYRINT 137
Query: 104 IAPVILTKELLDFIPEGGKVVFIISGASHVYTLDL--PGYGASKVALHYMAKVLEEELKE 161
+AP+ LT+ L + + I G SH T G+GASK AL+Y+ KV +E +
Sbjct: 138 VAPMGLTRALFPLLKQSPDASVIFVGESHGETPKAYWGGFGASKAALNYLCKVAADEWER 197
Query: 162 RG 163
G
Sbjct: 198 FG 199
>pir||F70547 hypothetical protein Rv0547c - Mycobacterium tuberculosis (strain
H37RV) >gi|2114009|emb|CAB08958.1| (Z95558) hypothetical
protein Rv0547c [Mycobacterium tuberculosis]
Length = 294
Score = 70.6 bits (170), Expect = 2e-11
Identities = 59/190 (31%), Positives = 91/190 (47%), Gaps = 25/190 (13%)
Query: 8 RVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKY---------IVVDLSTY 58
R+LLTGAS GIG K+ V+ V R + L + + + DLS
Sbjct: 42 RILLTGASSGIGAAATKQFGLHRAVVVAVARRKDLLDAVADRITGDGGTAMSLPCDLSDM 101
Query: 59 EGISKVRESLK---GEIDVLINNAGFGLVKPLLE--HSWEELEGMFKVNAIAPVILTKEL 113
E I + E ++ G ID+LINNAG + +PL E W ++E +N AP+ L + L
Sbjct: 102 EAIDALVEDVEKRIGGIDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRGL 161
Query: 114 LDFIPEGGKVVFI-------ISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKV 166
+ E G I +S AS ++++ Y ASK AL +++++E E +G+
Sbjct: 162 APGMLERGDGHIINVATWGVLSEASPLFSV----YNASKAALSAVSRIIETEWGSQGVHS 217
Query: 167 LRVYPKQVAT 176
+Y VAT
Sbjct: 218 TTLYYPLVAT 227
>pir||T35242 probable oxidoreductase - Streptomyces coelicolor
>gi|3560025|emb|CAA20647.1| (AL031515) putative
oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 233
Score = 70.6 bits (170), Expect = 2e-11
Identities = 61/195 (31%), Positives = 92/195 (46%), Gaps = 20/195 (10%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALK----ELGIKYIVVDL-----STYEG 60
L+TG GIG +A+ L+ G V GR E+ L+ ELG ++ L +
Sbjct: 8 LITGGGSGIGAAVARRLLDAGQRVAVTGRGEERLRAFSAELGDPAGLLTLRGSAAEHTQV 67
Query: 61 ISKVRESLK--GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIP 118
+S V +LK G ID ++ NAGF + E M N + P +L + +D +
Sbjct: 68 VSAVEATLKEFGRIDTVVANAGFATHDSVAEGDPAGWTEMVLTNVLGPALLIRASIDALK 127
Query: 119 EG-GKVVFIISGASHVYTLDLPG--YGASKVALHYMAKVLEEELKERGIKVLRVYPKQVA 175
G++V + S A V T PG YGA+K A+ +A+ E+ + G+ V + P +V
Sbjct: 128 ATRGRIVLVGSVAGFVNT---PGNIYGATKWAVTGLAENTRREVTQWGVGVTLIAPGRVE 184
Query: 176 TDFWKGAKLRGALSP 190
T FW G G L P
Sbjct: 185 TPFWDGT---GGLPP 196
>pir||T47668 oxidoreductase-like protein - Arabidopsis thaliana (fragment)
>gi|7019662|emb|CAB75763.1| (AL132954)
oxidoreductase-like protein [Arabidopsis thaliana]
Length = 273
Score = 70.6 bits (170), Expect = 2e-11
Identities = 65/234 (27%), Positives = 109/234 (45%), Gaps = 30/234 (12%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL----------GIKYIVVDLSTY 58
VL+TGAS GIG+E+ +L + G +VI R L L GI+ ++L
Sbjct: 16 VLVTGASSGIGREICLDLAKAGCQVIAAARRVDRLNSLCSEINSFSSTGIQAAALELDVS 75
Query: 59 EGISKVRESLK------GEIDVLINNAGF-GLVKPLLEHSWEELEGMFKVNAIAPVILTK 111
+ ++++++ G+ID LINNAG G VK L+ S +E + +FK N P +++K
Sbjct: 76 SDAATIQKAVREAWDIFGKIDALINNAGIRGNVKSSLDLSEDEWDNVFKTNLKGPWLVSK 135
Query: 112 E---LLDFIPEGGKVVFIISGASHVYTLDLPG---YGASKVALHYMAKVLEEELKERGIK 165
L+ GG V+ I S A LPG Y SK + M++++ EL G+
Sbjct: 136 HVCMLMRDAKRGGSVINISSIAG--IRGMLPGGLAYACSKGGVDTMSRMMALEL---GVH 190
Query: 166 VLRVYPKQVATDFWKGAKLRGALSPEYVARKIVNAIESDKRELFIPWYLKLAKF 219
+RV +A +K +G + E++ + ++ P L ++
Sbjct: 191 KIRV--NSIAPGLFKSEITQGLMQKEWLKNVTERTVPLKVQQTVDPGLTSLVRY 242
>dbj|BAB04657.1| (AP001510) glucose 1-dehydrogenase [Bacillus halodurans]
Length = 249
Score = 70.6 bits (170), Expect = 2e-11
Identities = 55/183 (30%), Positives = 89/183 (48%), Gaps = 15/183 (8%)
Query: 10 LLTGASGGIGQELAKELIRRGYE-VIGVGRNEKALKEL-------GIKYIVVDLST---- 57
L+TG+S GIG+E+A L RGY+ VI R+ KA +E G+K ++V +
Sbjct: 7 LVTGSSRGIGKEIALRLADRGYDLVINYARSRKAAEETAAEIEQKGVKALIVKANVGKRD 66
Query: 58 -YEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
E + + G +DV +NNA G+++PL+E + +N+ A + +E
Sbjct: 67 KIEELFAQIDDTYGRLDVFVNNAASGVLRPLMELEESHWDWTMDINSKALLFCAQEAAKR 126
Query: 117 IPE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQV 174
+ + GGK+V + S + Y + G SK A+ + + L EL + I V V V
Sbjct: 127 MEKNGGGKIVSLSSLGAIRYLKNYTTVGVSKAAVEALTRYLAVELAPKNIVVNAVSGGAV 186
Query: 175 ATD 177
TD
Sbjct: 187 DTD 189
>emb|CAC13079.1| (AL445503) putative oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 312
Score = 70.6 bits (170), Expect = 2e-11
Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 16/223 (7%)
Query: 10 LLTGASGGIGQELAKEL-IRRGYEVIGVGRNEKALKELG----IKYIVVDLSTYEGISKV 64
L+TGAS GIG +A+ L G+ ++ GR+ L+++ DL+ ++
Sbjct: 70 LVTGASSGIGAAVARRLGDEDGWRLVLTGRDPVRLRQVADDTSATAFAADLTLPGAGRQL 129
Query: 65 RE---SLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD-FIPEG 120
+ + G +D+L+ AG G L+ ++ + VN +A + L + LL + G
Sbjct: 130 TDFTLATAGPVDLLVAGAGVGWAGEFLDMPPRTIDDVLDVNLLATLRLVRLLLPGMVAAG 189
Query: 121 -GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFW 179
G+VV I S A V D Y A+K A+ A L EL+ G+ V V P V T F+
Sbjct: 190 SGRVVLIGSLAGSVAVRDEAVYSAAKAAIGAFADSLRYELRGTGVGVTHVVPGVVDTPFF 249
Query: 180 --KGAKLRGA----LSPEYVARKIVNAIESDKRELFIPWYLKL 216
+GA R + + PE VA + A+ + E+++P +L+L
Sbjct: 250 ERRGAPYRRSWPRPVPPERVADAVRTAVLRGRDEVYVPSWLRL 292
>gb|AAA50845.1| (J05282) insect-type dehydrogenase [Burkholderia cepacia]
Length = 249
Score = 70.2 bits (169), Expect = 2e-11
Identities = 47/168 (27%), Positives = 85/168 (49%), Gaps = 6/168 (3%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKA---LKELGIKYIVVDLSTYEGISKVR 65
VL+TG S G G E+A+ + R ++V+ R + ++ + +D++ + I
Sbjct: 4 VLITGCSSGFGLEIARHFLARDWQVVATMRTPREDVLPPSERLRVLALDVTNTDSIRAAI 63
Query: 66 ESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL-DFIPEGGKVV 124
++ G IDVL+NNAGFG P + + +F+ N I + +T+ +L F G V+
Sbjct: 64 DAA-GPIDVLVNNAGFGAAAPAELTPLDTVRALFETNTIGTIAVTQAVLPQFRRRGAGVI 122
Query: 125 FIISGASHVYTLDLPG-YGASKVALHYMAKVLEEELKERGIKVLRVYP 171
++ + + L L G Y ASK A++ + + EL+ G++ V P
Sbjct: 123 VNVTSSVTLKVLPLVGAYRASKAAVNAFTESMAVELEPFGVRAHLVLP 170
>sp|P50199|GNO_GLUOX GLUCONATE 5-DEHYDROGENASE (5-KETO-D-GLUCONATE 5-REDUCTASE)
>gi|2120837|pir||A57149 gluconate 5-dehydrogenase (EC
1.1.1.69) - Gluconobacter oxydans
>gi|563366|emb|CAA56322.1| (X80019) gluconate
oxidoreductase [Gluconobacter oxydans]
Length = 256
Score = 70.2 bits (169), Expect = 2e-11
Identities = 60/189 (31%), Positives = 94/189 (48%), Gaps = 16/189 (8%)
Query: 4 LNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL-------GIK-----YI 51
L+ R L+TGAS GIG LAK L R G EV+ GRN ++L G+K +
Sbjct: 9 LSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAVFD 68
Query: 52 VVDL-STYEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILT 110
V D + +G++ + + G ID+LINNAG PL E S ++ + + N A +
Sbjct: 69 VTDQDAVIDGVAAIERDM-GPIDILINNAGIQRRAPLEEFSRKDWDDLMSTNVNAVFFVG 127
Query: 111 KELL-DFIPEG-GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLR 168
+ + IP G GK+V I S S + + Y A+K A+ + K + + G+++
Sbjct: 128 QAVARHMIPRGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRHGLQING 187
Query: 169 VYPKQVATD 177
+ P AT+
Sbjct: 188 LAPGYFATE 196
>emb|CAB69764.1| (AL137187) putative dehydrogenase/reductase [Streptomyces
coelicolor A3(2)]
Length = 247
Score = 70.2 bits (169), Expect = 2e-11
Identities = 52/185 (28%), Positives = 84/185 (45%), Gaps = 9/185 (4%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKAL----KELGIKYIVV--D 54
MG + ++ G G+G +A+ L+ G V+ GR++ L + LG + V D
Sbjct: 1 MGMYSNRNAVIAGGGSGMGFAMAELLVAGGARVVITGRSQATLDAARERLGENAVAVRGD 60
Query: 55 LSTYEGISKVRESLKGEI---DVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTK 111
+++ + + + +K E+ D L NAG + PL + E + +F +N +
Sbjct: 61 VASLPDLDALTDRVKAELGTLDALFVNAGIATLTPLESTTEEAYDELFDINVKGAWFTVQ 120
Query: 112 ELLDFIPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYP 171
+L + G VV S A+ + D Y A K AL MA+ EL RGI+V V P
Sbjct: 121 KLAPLLNTGAGVVLTTSVANVIGMTDTSVYAAGKAALRSMARSFSRELLPRGIRVNAVSP 180
Query: 172 KQVAT 176
V T
Sbjct: 181 GPVDT 185
>pir||F81117 oxidoreductase, short chain dehydrogenase/reductase family NMB1127,
NMB1165 [imported] - Neisseria meningitidis (group B
strain MD58) >gi|7226364|gb|AAF41515.1| (AE002462)
oxidoreductase, short chain dehydrogenase/reductase
family [Neisseria meningitidis MC58]
>gi|7226402|gb|AAF41550.1| (AE002465) oxidoreductase,
short chain dehydrogenase/reductase family [Neisseria
meningitidis MC58]
Length = 239
Score = 70.2 bits (169), Expect = 2e-11
Identities = 56/182 (30%), Positives = 91/182 (49%), Gaps = 19/182 (10%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEK-------ALKELGIK---Y 50
M L+ +L+TGAS G+G+++AK G VI V R++K A+ E G
Sbjct: 1 MATLSDKTILVTGASQGLGEQVAKAYAAAGATVILVARHQKKLEKVYDAIVEAGYPEPFA 60
Query: 51 IVVDLSTYEG------ISKVRESLKGEIDVLINNAG-FGLVKPLLEHSWEELEGMFKVNA 103
I DL + E + + E+ +G++D +++ AG F + PL + E +++N
Sbjct: 61 ICFDLISAEEKEFEHFAATIAEATQGKLDGIVHCAGYFYALSPLDFQTVAEWVNQYRINT 120
Query: 104 IAPVILTKELLDFIPEGGKVVFIISGASHVYTLDL--PGYGASKVALHYMAKVLEEELKE 161
+AP+ LT+ L + + I G SH T G+GASK AL+Y+ KV +E +
Sbjct: 121 VAPMGLTRALFPLLKQSPDASVIFVGESHGETPKAYWGGFGASKAALNYLCKVAADEWER 180
Query: 162 RG 163
G
Sbjct: 181 FG 182
>gb|AAF50980.1| (AE003575) CG15629 gene product [Drosophila melanogaster]
Length = 325
Score = 70.2 bits (169), Expect = 2e-11
Identities = 63/229 (27%), Positives = 104/229 (44%), Gaps = 22/229 (9%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL----------GIKYIVVDLST- 57
VL+TG GG+G+ +A R ++ N++A+K K VVD+S
Sbjct: 59 VLITGGGGGVGRLIALNFARLQARIVIWDINQEAIKTTVDLLAKHGYDNCKGYVVDISDR 118
Query: 58 ---YEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL 114
Y+ S+V E + G +D+LINNAG KP E ++ + +N I+ K L
Sbjct: 119 EQIYQRASQVTEEV-GPVDILINNAGIVCCKPFWELHDRVIQNTYNINIISHYWTVKAFL 177
Query: 115 DFIPEG--GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERG---IKVLRV 169
+ G +V + S + T Y A+K A + L +LK G I++ +
Sbjct: 178 PHMMRNNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHGYDQIQMSLI 237
Query: 170 YPKQVATDFWKGAKLR--GALSPEYVARKIVNAIESDKRELFIPWYLKL 216
P + T + G + R L P+YVA +I NA+ ++ +P ++L
Sbjct: 238 CPYYINTGMFSGVRPRMMPMLEPQYVADRIENAVRCNEVWCVLPNSIRL 286
>gi|7657478 photoreceptor outer segment all-trans retinol dehydrogenase [Homo
sapiens] >gi|7527474|gb|AAF63160.1|AF229845_1 (AF229845)
photoreceptor outer segment all-trans retinol
dehydrogenase [Homo sapiens]
Length = 311
Score = 70.2 bits (169), Expect = 2e-11
Identities = 63/187 (33%), Positives = 94/187 (49%), Gaps = 19/187 (10%)
Query: 9 VLLTGASGGIGQELAKELI---RRGYEVIGVGRN-------EKALKE-LGIKYIV--VDL 55
VL++G S GIG ELA +L ++ Y+V+ R+ E A E LG V +D+
Sbjct: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
Query: 56 STYEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD 115
+ E +++ ++GE+DVL+NNAG GLV PL S ++ +F N V L K +L
Sbjct: 68 CSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLP 127
Query: 116 FIP--EGGKVVFI--ISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYP 171
+ G +V I + G V D+ Y ASK AL + L +L + I + V P
Sbjct: 128 GMKRRRQGHIVVISSVMGLQGVIFNDV--YAASKFALEGFFESLAIQLLQFNIFISLVEP 185
Query: 172 KQVATDF 178
V T+F
Sbjct: 186 GPVVTEF 192
>gi|11424840 photoreceptor outer segment all-trans retinol dehydrogenase [Homo
sapiens]
Length = 331
Score = 70.2 bits (169), Expect = 2e-11
Identities = 63/187 (33%), Positives = 94/187 (49%), Gaps = 19/187 (10%)
Query: 9 VLLTGASGGIGQELAKELI---RRGYEVIGVGRN-------EKALKE-LGIKYIV--VDL 55
VL++G S GIG ELA +L ++ Y+V+ R+ E A E LG V +D+
Sbjct: 28 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 87
Query: 56 STYEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD 115
+ E +++ ++GE+DVL+NNAG GLV PL S ++ +F N V L K +L
Sbjct: 88 CSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLP 147
Query: 116 FIP--EGGKVVFI--ISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYP 171
+ G +V I + G V D+ Y ASK AL + L +L + I + V P
Sbjct: 148 GMKRRRQGHIVVISSVMGLQGVIFNDV--YAASKFALEGFFESLAIQLLQFNIFISLVEP 205
Query: 172 KQVATDF 178
V T+F
Sbjct: 206 GPVVTEF 212
>gi|6322227 Yir036cp [Saccharomyces cerevisiae] >gi|731923|sp|P40580|YIV6_YEAST
HYPOTHETICAL OXIDOREDUCTASE IN LYS1-HYR1 INTERGENIC
REGION >gi|626387|pir||S48498 oxidoreductase homolog
YIR036c - yeast (Saccharomyces cerevisiae)
>gi|557842|emb|CAA86196.1| (Z38061) orf, len: 263, CAI:
0.12, similar to orf (32877..33641) and BA71_EUBSP
P07914 7-ALPHA -HYDROXYSTEROID DEHYDROGENASE
[Saccharomyces cerevisiae]
Length = 263
Score = 69.9 bits (168), Expect = 3e-11
Identities = 62/208 (29%), Positives = 94/208 (44%), Gaps = 22/208 (10%)
Query: 9 VLLTGASGGIGQELAKELIRRGYE--VIGVGRNEKALKELGIKY----------IVVDLS 56
+L+TGAS GIG +L K +I E V GV R E L+ L +Y + D S
Sbjct: 5 ILITGASRGIGLQLVKTVIEEDDECIVYGVARTEAGLQSLQREYGADKFVYRVLDITDRS 64
Query: 57 TYEGISKVRESLKGEIDVLINNAGF-----GLVKPLLEHSWEELEGMFKVN---AIAPVI 108
E + + G++D ++ NAG + + EH ++ E +F VN ++ V
Sbjct: 65 RMEALVEEIRQKHGKLDGIVANAGMLEPVKSISQSNSEHDIKQWERLFDVNFFSIVSLVA 124
Query: 109 LTKELLDFIPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLR 168
L LL P G +VF+ SGAS YG SK AL++ A + E ++ +
Sbjct: 125 LCLPLLKSSPFVGNIVFVSSGASVKPYNGWSAYGCSKAALNHFAMDIASEEPSDKVRAVC 184
Query: 169 VYPKQVATDFWKGAKLRGALSPEYVARK 196
+ P V T K +R L P+ + K
Sbjct: 185 IAPGVVDTQMQK--DIRETLGPQGMTPK 210
>pir||B69802 glucose 1-dehydrogenase homolog yfhR - Bacillus subtilis
>gi|1673388|emb|CAB04808.1| (Z82044) unidentfied
dehydrogenase [Bacillus subtilis]
>gi|2633188|emb|CAB12693.1| (Z99108) alternate gene
name: ygaA~similar to glucose 1-dehydrogenase [Bacillus
subtilis] >gi|2804548|dbj|BAA24484.1| (D85082) YfhR
[Bacillus subtilis]
Length = 250
Score = 69.9 bits (168), Expect = 3e-11
Identities = 56/187 (29%), Positives = 92/187 (48%), Gaps = 17/187 (9%)
Query: 10 LLTGASGGIGQELAKELIRRGYE-VIGVGRNEKA-------LKELGIKYIVVDLSTYEGI 61
L+TG+S G+G+ A L GY VI R++KA +++LG+K +VV + +
Sbjct: 8 LVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKANVGQP- 66
Query: 62 SKVRESLK------GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD 115
+K++E + G +DV +NNA G+++P++E + +NA A + +E
Sbjct: 67 AKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQEAAK 126
Query: 116 FIPE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQ 173
+ + GG +V I S S Y + G SK AL + + L EL + I V V
Sbjct: 127 LMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVSGGA 186
Query: 174 VATDFWK 180
+ TD K
Sbjct: 187 IDTDALK 193
>gi|9789991 cDNA sequence AF064635; putative steroid dehydrogenase [Mus
musculus] >gi|3913473|sp|O70503|DHBK_MOUSE PUTATIVE
STEROID DEHYDROGENASE KIK-I >gi|3142702|gb|AAC16885.1|
(AF064635) putative steroid dehydrogenase [Mus musculus]
Length = 312
Score = 69.9 bits (168), Expect = 3e-11
Identities = 56/188 (29%), Positives = 93/188 (48%), Gaps = 17/188 (9%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG----------IKYIVVDLSTYE 59
++TG + GIG+ A+EL +RG +++ + R++ L ++ + I VD S +
Sbjct: 54 VVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDD 113
Query: 60 GISKVRESLKG-EIDVLINNAGFGLVKPLLEHSWEELEGMFK----VNAIAPVILTKELL 114
K++ L G EI VL+NN G P +L+ K +N ++ +T+ +L
Sbjct: 114 IYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVL 173
Query: 115 DFIPEGGK-VVFIISGASHVYTLD-LPGYGASKVALHYMAKVLEEELKERGIKVLRVYPK 172
+ E K V+ IS AS + + L Y A+K + + ++ L EE K +GI V V P
Sbjct: 174 PGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPY 233
Query: 173 QVATDFWK 180
VAT K
Sbjct: 234 LVATKLAK 241
>emb|CAA07768.1| (AJ007932) ketoreductase [Streptomyces argillaceus]
Length = 247
Score = 69.9 bits (168), Expect = 3e-11
Identities = 56/181 (30%), Positives = 84/181 (45%), Gaps = 14/181 (7%)
Query: 7 MRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG-----IKYIVVDLSTYEGI 61
+ V++TG GIG+ A+ +G V+ VGR L+E I+ V DL+ +
Sbjct: 9 LSVVVTGGGSGIGRATARAYAAQGAHVLVVGRTAGHLEETAEGQPRIRAFVADLADRDAP 68
Query: 62 SKVRESL---KGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIP 118
++ + G IDVL+NNA L E E E N + P+ LT+ + +P
Sbjct: 69 ERIVAAALDATGGIDVLVNNAAVPWRARLGEIDRERAERQVATNLLGPLFLTQSAVPHMP 128
Query: 119 EGGKVVFIISGASHVYTLDLPG---YGASKVALHYMAKVLEEELKERGIKVLRVYPKQVA 175
G VV I +S+ T P YG++KV L ++ EL RGI+V+ V P
Sbjct: 129 AGATVVNI---SSNPPTRGWPANSVYGSTKVGLDFLTLTWAVELAPRGIRVVSVAPGPTL 185
Query: 176 T 176
T
Sbjct: 186 T 186
>pir||T29125 ketoacyl reductase homolog - Streptomyces coelicolor
>gi|3451448|emb|CAA20507.1| (AL031350) putative
dehydrogenase [Streptomyces coelicolor A3(2)]
Length = 276
Score = 69.9 bits (168), Expect = 3e-11
Identities = 57/198 (28%), Positives = 94/198 (46%), Gaps = 17/198 (8%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG----------IKYIVVDLSTYE 59
L+TGAS G+G+ A+EL RG ++ V R+ AL L + I DLS
Sbjct: 10 LVTGASKGLGEAYARELASRGAHLVLVARSADALHALADEIRATHSVRVDVIAADLSDRR 69
Query: 60 GISKVRESLKG---EIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
+V +++ G ++D+L+NNAG G V P L VN A V L L
Sbjct: 70 SPQRVLDAVDGLGLDVDLLVNNAGMGAVGPFLVRPLAPNLQSVDVNVTALVGLVHLLGAR 129
Query: 117 IPEGGK--VVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQV 174
+ E G+ +V I S A+ Y A+K + + + EE++ G++V+ +P
Sbjct: 130 MVERGRGGIVNIASTAAFQPMPYQASYAATKAFVLSFTEAVAEEVRGTGVRVMAAHPGAT 189
Query: 175 ATDFWKGAKLRGALSPEY 192
AT F+ + +++P++
Sbjct: 190 ATGFFD--RTTASMNPKF 205
>gb|AAD13552.1| (AF080235) reductase homolog [Streptomyces cyanogenus]
Length = 253
Score = 69.9 bits (168), Expect = 3e-11
Identities = 60/193 (31%), Positives = 89/193 (46%), Gaps = 25/193 (12%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKEL--------------------IRRGYEVIGVGRNE 40
MG L L+TGAS GIG+ +A++L + E G GR
Sbjct: 1 MGNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDG-GRAF 59
Query: 41 KALKELGIKYIVVDLSTYEGISKVRESLKG--EIDVLINNAGFGLVKPLLEHSWEELEGM 98
ELG+ V L +EG+ + + G ++D+L+NNAG + E + E + M
Sbjct: 60 TVKAELGVPGDVDVL--FEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRM 117
Query: 99 FKVNAIAPVILTKELLDFIPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEE 158
VNA AP + + L +P+GG+++ + SG + V + D YG SK AL +A
Sbjct: 118 MAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRH 177
Query: 159 LKERGIKVLRVYP 171
L R I V V P
Sbjct: 178 LGSRRITVNSVAP 190
>pir||D83042 probable short-chain dehydrogenase PA4832 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951101|gb|AAG08217.1|AE004896_7 (AE004896) probable
short-chain dehydrogenase [Pseudomonas aeruginosa]
Length = 265
Score = 69.9 bits (168), Expect = 3e-11
Identities = 58/217 (26%), Positives = 102/217 (46%), Gaps = 19/217 (8%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG----------IKYIVVDLSTYE 59
L+TGAS GIG A+ L RRG++++ V R+ + L+ L ++ + DLS +
Sbjct: 11 LVTGASSGIGATYAEHLARRGHDLLLVARDRQRLEALADRLRQAHGVRVEILRADLSERD 70
Query: 60 GISKVRESLKGE--IDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFI 117
+V L+ + I +L+NNAG + PL + + E M +N +A L +
Sbjct: 71 DRLRVERRLRDDASIALLVNNAGVAMNGPLADADMDRAERMIALNVVALTRLAAGAAEGF 130
Query: 118 PE--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVA 175
GG +V + S + L Y A+K + +++ L+ EL G+ V V P
Sbjct: 131 RRRGGGAIVNLGSVVALAPELFNAVYSATKAYVLSLSQSLQHELAGSGVYVQAVLPGVTR 190
Query: 176 TDFWKGAKLRGALSPEYVARKIVNAIES-----DKRE 207
T+ W+ + A P + ++ + +E+ D+RE
Sbjct: 191 TEIWERSGTGIAGIPAEMVMEVEDLVEAALVGFDRRE 227
>sp|O05730|VDLC_HELPY PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE VDLC
Length = 284
Score = 69.5 bits (167), Expect = 3e-11
Identities = 66/230 (28%), Positives = 104/230 (44%), Gaps = 34/230 (14%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEK---ALKELGIKYIVVDLSTYEGISKVRE 66
++TGAS GIG E A L+ +GY+V + R+ AL + + +D+S + +V
Sbjct: 14 IITGASSGIGLECALMLLDQGYKVYALSRHATLCVALNHALCESVDIDVSDSNALKEVFS 73
Query: 67 SLKGE---IDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEG--G 121
++ + DVLIN+AG+G+ + + EE++ F VN A + + L +
Sbjct: 74 NISAKEKYCDVLINSAGYGVFGSVEDTPIEEVKKQFSVNFFALCEVVQFCLPLLKNKPHS 133
Query: 122 KVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDFWKG 181
K+ + S A V L L Y ASK AL + L ELK ++V + P V +++ K
Sbjct: 134 KIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLELKPFNVQVCLIEPGPVKSNWEKT 193
Query: 182 A--------------------------KLRGALSPEYVARKIVNAIESDK 205
A + ALSP+ VA+KIV S K
Sbjct: 194 AFSVENFESEDSLYALEVNAAKSFYSGVYQNALSPKAVAQKIVFLSMSQK 243
>emb|CAB61164.1| (AL132973) short chain oxidoreductase [Streptomyces coelicolor
A3(2)]
Length = 265
Score = 69.5 bits (167), Expect = 3e-11
Identities = 62/217 (28%), Positives = 102/217 (46%), Gaps = 18/217 (8%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNE------KALKELGIKYIVV--DLSTYEGI 61
L+TGAS GIG ELA GY+++ +E + L+E G++ V DL +G+
Sbjct: 9 LVTGASSGIGYELAALFAEHGYDLVVNAEDERLEHAARRLRETGVRVRAVRADLRHPDGV 68
Query: 62 SKVRESLKG-EIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL-DFIPE 119
+ +L G +DV NAG G ++ + + + ++ A V L K LL D +
Sbjct: 69 DHLIAALTGLAVDVAALNAGVGQGGAFVDTDLADDQSVIDLDVTATVRLAKPLLRDMVAR 128
Query: 120 G-GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATDF 178
G G+++F S A+ + Y ASK + A+ L+EE+ G+ V P TDF
Sbjct: 129 GVGRLMFTSSVAATMPGSFQSVYNASKSFVQSFAQALQEEVAGTGVTVTSFMPGPTETDF 188
Query: 179 WKGAKLRGAL-------SPEYVARKIVNAIESDKREL 208
++ A + P VAR+ +A+ + +L
Sbjct: 189 FRRAGMVDTKVGTMPKDDPAQVARQAFDAVMKGRGKL 225
>gi|10955028 mas1' [Agrobacterium tumefaciens] >gi|1708926|sp|P50202|MAS1_AGRTU
AGROPINE SYNTHESIS REDUCTASE >gi|281655|pir||S28707
hypothetical protein 25 - Agrobacterium tumefaciens
plasmid pTi15955 >gi|39087|emb|CAA25187.1| (X00493) open
reading frame 25 [Agrobacterium tumefaciens]
>gi|8572685|gb|AAF77131.1| (AF242881) mas1'
[Agrobacterium tumefaciens]
Length = 430
Score = 69.1 bits (166), Expect = 5e-11
Identities = 59/218 (27%), Positives = 106/218 (48%), Gaps = 16/218 (7%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEV-IGVGRNEKALKELG--------IKYIVVDLSTYE 59
V+++G + GIG+ +A++LIR GY V +G + + G ++ +D S+ +
Sbjct: 202 VMVSGVTRGIGKAIAEDLIRHGYRVSLGARNIQDLVAAFGDENEALHYARFDALDHSSMK 261
Query: 60 GISKVRESLKGEIDVLINNAGFG-LVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIP 118
+ ID L+NNAG G V E + E L+ + +N +AP+I+TK + ++
Sbjct: 262 DWVDTTIAKFNRIDGLVNNAGCGDHVDLEKEINVELLQKQWDINCVAPLIMTKLCMPYLI 321
Query: 119 E--GGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
E G++V + S + L GY +K L + K + + G++ + + P VAT
Sbjct: 322 ESGSGRIVNLNSMSGQRVANSLVGYNMTKHGLAGLTKTTQHVGWDHGVRAVDICPGFVAT 381
Query: 177 DFWKGAKLRG---ALSPEYVARKIVNAIESDKRELFIP 211
+ L G + PE +A+ + A+E R F+P
Sbjct: 382 NMSSWTNLIGPDEMIQPEDIAKLVRAAMERPNR-AFVP 418
>sp|P43713|FABG_HAEIN 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|1073790|pir||D64051
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100) - Haemophilus influenzae (strain Rd KW20)
>gi|1573112|gb|AAC21824.1| (U32701) 3-ketoacyl-acyl
carrier protein reductase (fabG) [Haemophilus influenzae
Rd]
Length = 242
Score = 69.1 bits (166), Expect = 5e-11
Identities = 54/179 (30%), Positives = 91/179 (50%), Gaps = 11/179 (6%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGI------KYIVVDLSTYEGISK 63
L+TG++ GIG+ +A+EL +G VIG +EK + + K +V++++ E I
Sbjct: 7 LVTGSTRGIGRAIAEELSSKGAFVIGTATSEKGAEAISAYLGDKGKGLVLNVTDKESIET 66
Query: 64 VRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDFIPEG 120
+ E +K G+ID+L+NNAG L+ EE + + N + L+K +L + +
Sbjct: 67 LLEQIKNDFGDIDILVNNAGITRDNLLMRMKDEEWFDIMQTNLTSVYHLSKAMLRSMMKK 126
Query: 121 --GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVATD 177
G+++ I S Y A+K + +K L +E+ RGI V V P +ATD
Sbjct: 127 RFGRIINIGSVVGSTGNPGQTNYCAAKAGVVGFSKSLAKEVAARGITVNVVAPGFIATD 185
>pir||F69868 glucose 1-dehydrogenase homolog ykvO - Bacillus subtilis
>gi|2633748|emb|CAB13250.1| (Z99111) similar to glucose
1-dehydrogenase [Bacillus subtilis]
Length = 248
Score = 69.1 bits (166), Expect = 5e-11
Identities = 53/186 (28%), Positives = 89/186 (47%), Gaps = 10/186 (5%)
Query: 1 MGFLNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNE----KALKELG--IKYIVVD 54
MG L+TG + GIG A++ + G V GR + KA+ ++G + + D
Sbjct: 1 MGKFEGKIALVTGGTSGIGLATAQKFVNEGAYVYITGRRQNELDKAVNQIGKNVTGVQGD 60
Query: 55 LSTYEGISKVRESLK---GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTK 111
+S E + K+ + +K G++D+L NAG G PL E + E+++ F +N + +
Sbjct: 61 ISKLEDLDKLYDIIKQEKGKLDILFANAGIGNFLPLGEITEEQVDRTFDINVKGTIFTVQ 120
Query: 112 ELLDFIPEG-GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVY 170
+ L P+ G ++ S A + YGASK AL + + +LK I+V V
Sbjct: 121 KALSLFPDKVGSIIVTGSTAGSIGNPAFSVYGASKAALRALVRNWILDLKGTEIRVNVVS 180
Query: 171 PKQVAT 176
P + T
Sbjct: 181 PGGILT 186
>gb|AAF19703.1|AC008047_10 (AC008047) F2K11.24 [Arabidopsis thaliana]
Length = 287
Score = 68.7 bits (165), Expect = 6e-11
Identities = 56/195 (28%), Positives = 93/195 (46%), Gaps = 22/195 (11%)
Query: 9 VLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKEL----------GIKYIVVDLSTY 58
VL+TGAS GIG+E+ +L + G +++ R L L G++ + ++L
Sbjct: 27 VLVTGASSGIGREICLDLCKAGCKIVAAARRVDRLNSLCSEINSFGAIGVQAVALELDVS 86
Query: 59 EGISKVRESLK------GEIDVLINNAGF-GLVKPLLEHSWEELEGMFKVNAIAPVILTK 111
+R+++K G+IDVLINNAG G VK L+ S EE + +F+ N +++K
Sbjct: 87 SEADTIRKAVKEAWETFGKIDVLINNAGIRGNVKSSLDLSEEEWDKVFRTNLTGSWLISK 146
Query: 112 E---LLDFIPEGGKVVFI--ISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKV 166
L+ GG V+ + ISG Y SK + M +++ EL I+V
Sbjct: 147 YVCLLMRDAERGGSVINVSSISGLHRGLLRGGLAYACSKGGVDTMTRMMAIELAVYKIRV 206
Query: 167 LRVYPKQVATDFWKG 181
+ P ++ +G
Sbjct: 207 NSIAPGIFRSEITQG 221
>pir||E82748 tropinone reductase XF0913 [imported] - Xylella fastidiosa (strain
9a5c) >gi|9105832|gb|AAF83723.1|AE003930_13 (AE003930)
tropinone reductase [Xylella fastidiosa]
Length = 261
Score = 68.7 bits (165), Expect = 6e-11
Identities = 59/185 (31%), Positives = 87/185 (46%), Gaps = 20/185 (10%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKAL-------------KEL-GIKYIVVDL 55
L+TGAS GIG +A+EL+ G +V+ V RN L +EL G+ V D
Sbjct: 17 LITGASTGIGLAVARELLGLGADVLLVARNADLLGRVRDELAEEFPERELHGLAADVADD 76
Query: 56 STYEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLD 115
I E + VLINNAG + + LE++ +E +F++N + L +
Sbjct: 77 VDRRAILDWVEDCSNGLHVLINNAGGNVTRAALEYTEDEWREIFEINLFSAFELCRYTQP 136
Query: 116 FIPEGGKVVFI----ISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYP 171
+ + +SG +HV + +P YG SK ALH M + L E E GI+V V P
Sbjct: 137 LLACHASTAIVNIGSVSGLTHVRS-GVP-YGMSKAALHQMTRNLAVEWAEDGIRVNAVAP 194
Query: 172 KQVAT 176
+ T
Sbjct: 195 WYIRT 199
>gb|AAC25556.1| (AF013169) short chain alcohol dehydrogenase [Pyrococcus furiosus]
Length = 234
Score = 68.3 bits (164), Expect = 8e-11
Identities = 64/207 (30%), Positives = 96/207 (45%), Gaps = 22/207 (10%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVI----GVGRNEKALKELGIKYIVVDLSTYEGISK-- 63
++TGAS GIG+ +AK L GY + V R EK KEL K+ V Y +SK
Sbjct: 5 VITGASRGIGEAIAKALAEDGYSLALGARSVDRLEKIAKELSEKHGVEVFYDYLDVSKPE 64
Query: 64 -----VRESLK--GEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
R++L G++DV++ NAG G L E + E+ M +VN + K L+
Sbjct: 65 SVEEFARKTLAHFGDVDVVVANAGLGYFGRLEELTEEQFHEMIEVNLLGVWRTIKAFLNS 124
Query: 117 IPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEE--ELKERGIKVLRVYPKQV 174
+ G V +++ S V LP YG VA + A+ L +++ ++ + P V
Sbjct: 125 LKRTGGVAIVVT--SDVSARLLP-YGGGYVATKWAARALVRTFQIENPDVRFFELRPGAV 181
Query: 175 ATDFWKG----AKLRGALSPEYVARKI 197
T F K +G L PE VA +
Sbjct: 182 DTYFGGSKAGKPKEQGYLKPEEVAEAV 208
>gb|AAD37453.1| (AF074603) putative ketoacyl reductase; NonE [Streptomyces griseus
subsp. griseus]
Length = 271
Score = 68.3 bits (164), Expect = 8e-11
Identities = 56/182 (30%), Positives = 86/182 (46%), Gaps = 16/182 (8%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKY---------IVVDL----S 56
L+ GAS GIG +A+ L RG V VGR E LKE+ + +DL +
Sbjct: 14 LVAGASSGIGAAVARRLAARGSAVALVGRREPELKEVAESIRAAGGTALSLALDLAGPGA 73
Query: 57 TYEGISKVRESLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELLDF 116
E ++ L G + +L+ +AG + + E E +VN P +L +E+L
Sbjct: 74 PAEAVAATAAGL-GPVGLLVCSAGAIRLAAVHETEERHWERQLRVNLTVPFLLAREVLPG 132
Query: 117 IPEG--GKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQV 174
+ E G VV I SG GYG SK +H + +++ EE ++ GI+ + V P V
Sbjct: 133 MRERGFGWVVNIGSGVGSEVVPGSGGYGVSKHTVHRLTELIHEENRDLGIRAVTVAPGWV 192
Query: 175 AT 176
+T
Sbjct: 193 ST 194
>gb|AAF86624.1| (U87786) clavaldehyde dehydrogenase [Streptomyces clavuligerus]
Length = 247
Score = 68.3 bits (164), Expect = 8e-11
Identities = 49/181 (27%), Positives = 87/181 (47%), Gaps = 13/181 (7%)
Query: 10 LLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELG---------IKYIVVDLSTYEG 60
L+TGAS GIG+ A+ L G V R + L+ LG + + +D++ +G
Sbjct: 11 LITGASSGIGEATARALAAEGAAVAIAARRVEKLRALGDELTAAGAKVHVLELDVADRQG 70
Query: 61 ISKVRES---LKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKELL-DF 116
+ S G +D+L+NNAG L+ P+ + + M N + + +T+ L
Sbjct: 71 VDAAVASTVEALGGLDILVNNAGIMLLGPVEDADTTDWTRMIDTNLLGLMYMTRAALPHL 130
Query: 117 IPEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYPKQVAT 176
+ G VV + S A V + Y A+K ++ ++ L +E+ ERG++V+ + P T
Sbjct: 131 LRSKGTVVQMSSIAGRVNVRNAAVYQATKFGVNAFSETLRQEVTERGVRVVVIEPGTTDT 190
Query: 177 D 177
+
Sbjct: 191 E 191
>sp|P57432|FABG_BUCAI 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (3-KETOACYL-ACYL CARRIER
PROTEIN REDUCTASE) >gi|10039021|dbj|BAB13055.1|
(AP001119) 3-oxoacyl-[acyl-carrier protein] reductase
[Buchnera sp. APS]
Length = 244
Score = 68.3 bits (164), Expect = 8e-11
Identities = 56/187 (29%), Positives = 91/187 (47%), Gaps = 13/187 (6%)
Query: 4 LNYMRVLLTGASGGIGQELAKELIRRGYEVIGVGRNEKALKELGIKYI-------VVDLS 56
+N +TGA+ GIG+ +AK+LI++G +VIG E +K + Y+ V++L
Sbjct: 3 INRQTAFITGANQGIGKAIAKKLIKKGIQVIGTSTTEDGVKRIN-DYLEGNGFGFVLNLK 61
Query: 57 TYEGIS-KVRE--SLKGEIDVLINNAGFGLVKPLLEHSWEELEGMFKVNAIAPVILTKEL 113
+ I+ K++E K ID+LINNAG L+ E + + K N + L K +
Sbjct: 62 NIDSITEKIQEIYKKKHSIDILINNAGIKEDNLLVNMKSTEWDDVIKTNLSSVFHLVKSV 121
Query: 114 LDFI--PEGGKVVFIISGASHVYTLDLPGYGASKVALHYMAKVLEEELKERGIKVLRVYP 171
+ + G+++ I S ++ Y ASK L K L E+ +GI V V P
Sbjct: 122 IRSMIKKRQGRIITIGSVIAYTGNKGQVNYSASKSGLIGFHKSLALEVASKGITVNIVSP 181
Query: 172 KQVATDF 178
+ T+F
Sbjct: 182 GLIKTNF 188
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.142 0.406
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85598608
Number of Sequences: 2977
Number of extensions: 3573558
Number of successful extensions: 14257
Number of sequences better than 1.0e-10: 101
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 14083
Number of HSP's gapped (non-prelim): 102
length of query: 235
length of database: 189,106,746
effective HSP length: 54
effective length of query: 181
effective length of database: 156,788,448
effective search space: 28378709088
effective search space used: 28378709088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 164 (68.3 bits)