BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0346 (korA-2) DE:2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA-2) (385 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp... 774 0.0 pir||F71046 probable ferredoxin oxidoreductase alpha subunit - P... 740 0.0 pir||B71047 probable ferredoxin oxidoreductase alpha subunit - P... 438 e-122 pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp... 437 e-121 sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET... 418 e-116 pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 409 e-113 sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET... 409 e-113 pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 354 1e-96 pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 294 1e-78 gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit a... 278 7e-74 pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 261 1e-68 pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacte... 258 7e-68 gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:accepto... 256 3e-67 pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (s... 240 3e-62 dbj|BAB06093.1| (AP001515) pyruvate synthase alpha subunit [Baci... 210 3e-53 gb|AAG19013.1| (AE005001) pyruvate ferredoxin oxidoreductase, su... 202 5e-51 pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 196 3e-49 sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB... 196 3e-49 pir||A72519 probable 2-oxoacid--ferredoxin oxidoreductase alpha ... 186 4e-46 pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha... 184 1e-45 pir||S22396 pyruvate synthase (EC 1.2.7.1) alpha chain [validate... 176 4e-43 gb|AAG19514.1| (AE005043) putative 2-ketoglutarate ferredoxin ox... 176 4e-43 emb|CAB60189.1| (AL132824) putative oxidoreductase alpha-subunit... 175 1e-42 emb|CAC08296.1| (AL392148) putative oxidoreductase [Streptomyces... 175 1e-42 pir||F70864 probable oxidoreductase alpha subunit - Mycobacteriu... 169 5e-41 emb|CAC11404.1| (AL445063) probable pyruvate ferredoxin oxidored... 167 2e-40 emb|CAC11904.1| (AL445065) probable 2-oxoacid ferredoxin oxidore... 167 2e-40 gb|AAK42926.1| 2-oxoacid--ferredoxin oxidoreductase, alpha chain... 164 1e-39 pir||B72288 2-oxoacid ferredoxin oxidoreductase, alpha subunit -... 162 8e-39 emb|CAA75641.1| (Y15464) ferredoxin oxidoreductase-like (gamma a... 152 5e-36 pir||JC4919 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 152 5e-36 pir||G69170 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 142 7e-33 gi|11498355 2-oxoacid ferredoxin oxidoreductase, subunit alpha (... 131 1e-29 gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit... 116 5e-25 dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase al... 110 3e-23 sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 106 4e-22 pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex ae... 106 6e-22 gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 104 1e-21 gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 101 2e-20 pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase... 101 2e-20 emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin ox... 98 1e-19 sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA... 97 4e-19 pir||A71114 probable ferredoxin oxidoreductase alpha subunit - P... 95 2e-18 sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA... 95 2e-18 gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alph... 94 2e-18 emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin ox... 93 4e-18 sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 93 4e-18 pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit -... 93 4e-18 sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 93 4e-18 pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicob... 92 8e-18 pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter py... 92 8e-18 gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alp... 92 1e-17 pir||E75038 indolepyruvate ferredoxin oxidoreductase, chain alph... 92 1e-17 sp|O58495|IORA_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA ... 91 2e-17 gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (p... 90 4e-17 pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 -... 89 7e-17 sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 87 3e-16 pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex ae... 86 8e-16 gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 83 5e-15 pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolo... 83 5e-15 gb|AAK42250.1| Indolepyruvate ferredoxin oxidoreductase alpha su... 81 2e-14 gb|AAD28766.1| (AF132216) 2-oxoisovalerate oxidoreductase beta s... 81 3e-14 emb|CAC12141.1| (AL445066) indolepyruvate ferredoxin oxidoreduct... 80 3e-14 gi|11499084 indolepyruvate ferredoxin oxidoreductase, subunit al... 80 6e-14 gb|AAD17273.1| (AF119361) ferredoxin oxidoreductase a-subunit [F... 73 4e-12 pir||G75085 indolepyruvate ferredoxin oxidoreductase, chain alph... 71 2e-11 pir||D71055 probable indolepyruvate ferredoxin oxidoreductase al... 71 2e-11 sp|O07835|IORA_PYRKO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA ... 71 3e-11 >pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha (kora-2) PAB0346 - Pyrococcus abyssi (strain Orsay) >gi|5457939|emb|CAB49429.1| (AJ248284) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA-2) [Pyrococcus abyssi] Length = 385 Score = 774 bits (1977), Expect = 0.0 Identities = 385/385 (100%), Positives = 385/385 (100%) Query: 1 MRFPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQM 60 MRFPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQM Sbjct: 1 MRFPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQM 60 Query: 61 EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120 EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ Sbjct: 61 EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120 Query: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG Sbjct: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180 Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD Sbjct: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240 Query: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI Sbjct: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300 Query: 301 KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV 360 KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV Sbjct: 301 KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV 360 Query: 361 KLISKIGGEVHTPMEIVDFIRRDFS 385 KLISKIGGEVHTPMEIVDFIRRDFS Sbjct: 361 KLISKIGGEVHTPMEIVDFIRRDFS 385 >pir||F71046 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3258091|dbj|BAA30774.1| (AP000006) 385aa long hypothetical ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 385 Score = 740 bits (1890), Expect = 0.0 Identities = 363/385 (94%), Positives = 376/385 (97%) Query: 1 MRFPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQM 60 MR PFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL+DGVVIQM Sbjct: 1 MRLPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLIDGVVIQM 60 Query: 61 EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120 EDEI SIAA+IGASWAG KAMTATSGPGFSLMQENIGYAVMTETPIVVV+VQRGGPSTGQ Sbjct: 61 EDEIGSIAAVIGASWAGVKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRGGPSTGQ 120 Query: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180 PTLPSQGDIMQSIWGTHGDH+LIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG Sbjct: 121 PTLPSQGDIMQSIWGTHGDHTLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180 Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240 HMRERVYIPEPDEIEIVNRKLP +EEEAKLPFGDPHGD VPPMPIFG+GYRTYVTGLTHD Sbjct: 181 HMRERVYIPEPDEIEIVNRKLPGSEEEAKLPFGDPHGDGVPPMPIFGKGYRTYVTGLTHD 240 Query: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300 E+GRPRTVEREVHER+IRRI EKIE+NKKDIFDYEARELDDAE+AIVTTGIVARSALRAI Sbjct: 241 EKGRPRTVEREVHERLIRRIFEKIEKNKKDIFDYEARELDDAEIAIVTTGIVARSALRAI 300 Query: 301 KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV 360 KELR LGIKAGLLKINTIWPFDFELIEK+A KVERIYVPEMNLGQLYHLV+EGANGKAEV Sbjct: 301 KELRNLGIKAGLLKINTIWPFDFELIEKVAEKVERIYVPEMNLGQLYHLVKEGANGKAEV 360 Query: 361 KLISKIGGEVHTPMEIVDFIRRDFS 385 KLISKIGGEVHTPMEI+DFIRRD S Sbjct: 361 KLISKIGGEVHTPMEIIDFIRRDLS 385 >pir||B71047 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3258095|dbj|BAA30778.1| (AP000006) 408aa long hypothetical ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 408 Score = 438 bits (1114), Expect = e-122 Identities = 224/370 (60%), Positives = 271/370 (72%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71 F+ GDEAIA AI AGCRFYAGYPITP+SEI E MA +P V G +QMEDEI SIAA+I Sbjct: 36 FMMGDEAIAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIGSIAAMI 95 Query: 72 GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131 GASW G KAMTATSGPGFSLMQENIGYAVMTETPIVVV+VQR GPSTGQ T +QGD Q Sbjct: 96 GASWTGLKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRSGPSTGQATKGAQGDFFQ 155 Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191 + WGTHGDH +I +SP +V++AF TIRAFN+AEK RTPVI+L D +GH RE++ IP+P Sbjct: 156 ARWGTHGDHPMIAVSPISVEDAFWETIRAFNIAEKLRTPVIVLFDGILGHTREQIRIPDP 215 Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251 DE+EI RKLP +EEEAKLPFGDPHGD VPPMP+FG GY T+VTG TH E G +E Sbjct: 216 DEVEITYRKLPGSEEEAKLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275 Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311 VH++++RRI KIE+N+ YE DDAE+ +V+ G+ AR +L A+ + RE GIKAG Sbjct: 276 VHDKLVRRIHRKIEQNRDVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKAREEGIKAG 335 Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371 L T+ PF E + ++ KV I VPEMNLGQ+ V+ N +K ++KIGG Sbjct: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMVLEVQRFVNDDVILKGVNKIGGVPL 395 Query: 372 TPMEIVDFIR 381 T EI+ IR Sbjct: 396 TVEEILKEIR 405 >pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha (kora-1) PAB2359 - Pyrococcus abyssi (strain Orsay) >gi|5457936|emb|CAB49426.1| (AJ248284) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA-1) [Pyrococcus abyssi] Length = 408 Score = 437 bits (1111), Expect = e-121 Identities = 217/370 (58%), Positives = 273/370 (73%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71 F+ GDEA+A AI AGCRFYAGYPITP+SEI E MA +P V G +QMEDEIASIAA++ Sbjct: 36 FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95 Query: 72 GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131 GASW G K MTATSGPGFSLMQEN+GYAVMTETP+V+VDVQR GPSTGQ T +QGD Q Sbjct: 96 GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155 Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191 + WGTHGDH ++ +SP +V++AF TIRAFN+AE+ RTPV++L D +GH RE++ IP+P Sbjct: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215 Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251 DE+EIV RKLPQNEEEA+LPFGDPHGD VPPMP+FG GY T+VTG TH E G +E Sbjct: 216 DEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275 Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311 VH++++RRI KIE+N++ YE DDAE+ +V+ G+ AR +L A+ + R+ GIK G Sbjct: 276 VHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVG 335 Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371 L T+ PF E + ++ KV I VPEMNLGQ+ V+ N +K ++KIGG Sbjct: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395 Query: 372 TPMEIVDFIR 381 T EI+ IR Sbjct: 396 TVEEILREIR 405 >sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|2127893|pir||E64334 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanococcus jannaschii >gi|1592279|gb|AAB98264.1| (U67483) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA) [Methanococcus jannaschii] Length = 366 Score = 418 bits (1063), Expect = e-116 Identities = 208/368 (56%), Positives = 271/368 (73%), Gaps = 9/368 (2%) Query: 9 KADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIA 68 K +F+QG++A A+ AI AGCRF+AGYPITP++EI EAMA +P V G IQMEDEI SIA Sbjct: 2 KVEFMQGNQACAKGAIKAGCRFFAGYPITPSTEIAEAMARELPKVGGYYIQMEDEIGSIA 61 Query: 69 AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128 A+IGASW G KAMTATSGPGFSLMQENIG+A MTETP VVVD+QRGGPSTGQPT+ SQGD Sbjct: 62 AVIGASWGGLKAMTATSGPGFSLMQENIGFAYMTETPCVVVDIQRGGPSTGQPTMASQGD 121 Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188 +MQ WG+HGD+ +I L+PS+VQE +DFTI AFN AEKYR PV +++D VGHMRE+V + Sbjct: 122 MMQCRWGSHGDYEVIALAPSSVQEMYDFTIMAFNYAEKYRIPVFVMADEIVGHMREKVIL 181 Query: 189 PEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTV 248 D IEI+NRK P+ E+ K P+ P +P MP+FG GY ++TGLTHDERG P V Sbjct: 182 --HDNIEIINRKKPE-EKPCKKPY--PFDKLIPEMPVFGEGYNVHITGLTHDERGYP-DV 235 Query: 249 EREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGI 308 E H++++RRIV KI +NK +I +E L DAE+ V G +R+ A++ LRE G+ Sbjct: 236 SPETHDKLVRRIVNKIRKNKDEIIKWEGENL-DAEIVFVCYGSPSRTVKHAVRNLREKGL 294 Query: 309 KAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGG 368 G +++ T++PF +L++K+ K +++ VPEMNLGQ+Y+ V EV L+ KIGG Sbjct: 295 DVGYIRLITVYPFPDDLLKKL--KAKKVVVPEMNLGQIYYEVERVCKKAEEVILVDKIGG 352 Query: 369 EVHTPMEI 376 E+H P E+ Sbjct: 353 ELHRPEEL 360 >pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622136|gb|AAB85529.1| (AE000875) 2-oxoglutarate oxidoreductase, alpha subunit [Methanobacterium thermoautotrophicum] Length = 378 Score = 409 bits (1040), Expect = e-113 Identities = 202/369 (54%), Positives = 266/369 (71%), Gaps = 3/369 (0%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71 FIQG++A AR AI AGCRF+AGYPITP++EI E MAL +P GV +QMEDEI ++ A+I Sbjct: 8 FIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGVFVQMEDEIGALGAVI 67 Query: 72 GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131 GA W+G + MTATSGPGFSLMQE++GYA MTETP+V+V+VQRG PSTGQPT+ SQ D+MQ Sbjct: 68 GAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMMQ 127 Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191 + WG+HGD+ +I LSPS+VQE FDFT+RAFNLAE+YR PV+++ D VGHMRE++ I P Sbjct: 128 ARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDEIVGHMREKITI--P 185 Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251 D ++I R+ P E LPF P D VP MP FG GYR VTGLTHDE G P E Sbjct: 186 DRVKIRKRRGPSVPPEEFLPFSAPE-DGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNPE 244 Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311 H R+++R+ +KI R++ I D + +DA + +++ G +RS A+K RE G++AG Sbjct: 245 GHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVRAG 304 Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371 LKINT WPF + A + ++ V EMNLGQ+++ V+ A G AEV+L+ KIGGE+H Sbjct: 305 YLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFYEVQRVAAGMAEVELLPKIGGEIH 364 Query: 372 TPMEIVDFI 380 P EI++ I Sbjct: 365 RPEEILNMI 373 >sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) Length = 376 Score = 409 bits (1040), Expect = e-113 Identities = 202/369 (54%), Positives = 266/369 (71%), Gaps = 3/369 (0%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71 FIQG++A AR AI AGCRF+AGYPITP++EI E MAL +P GV +QMEDEI ++ A+I Sbjct: 6 FIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGVFVQMEDEIGALGAVI 65 Query: 72 GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131 GA W+G + MTATSGPGFSLMQE++GYA MTETP+V+V+VQRG PSTGQPT+ SQ D+MQ Sbjct: 66 GAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMMQ 125 Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191 + WG+HGD+ +I LSPS+VQE FDFT+RAFNLAE+YR PV+++ D VGHMRE++ I P Sbjct: 126 ARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDEIVGHMREKITI--P 183 Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251 D ++I R+ P E LPF P D VP MP FG GYR VTGLTHDE G P E Sbjct: 184 DRVKIRKRRGPSVPPEEFLPFSAPE-DGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNPE 242 Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311 H R+++R+ +KI R++ I D + +DA + +++ G +RS A+K RE G++AG Sbjct: 243 GHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVRAG 302 Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371 LKINT WPF + A + ++ V EMNLGQ+++ V+ A G AEV+L+ KIGGE+H Sbjct: 303 YLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFYEVQRVAAGMAEVELLPKIGGEIH 362 Query: 372 TPMEIVDFI 380 P EI++ I Sbjct: 363 RPEEILNMI 371 >pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain TM0878 [similarity] - Thermotoga maritima (strain MSB8) >gi|4981412|gb|AAD35959.1|AE001753_15 (AE001753) pyruvate:ferredoxin 2-oxidoreductase-related protein [Thermotoga maritima] Length = 386 Score = 354 bits (898), Expect = 1e-96 Identities = 191/373 (51%), Positives = 251/373 (67%), Gaps = 5/373 (1%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71 F+QG+EA A AI AGCRF+AGYPITP++EI E MA +P V GV +QMEDEIAS AA++ Sbjct: 8 FLQGNEACALGAIKAGCRFFAGYPITPSTEIAEVMARELPKVGGVFVQMEDEIASAAAVV 67 Query: 72 GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131 GAS AG K+MTATSGPGFSL+QE IGYA+MTETP V +V R GPSTG PT P+QGDIMQ Sbjct: 68 GASLAGVKSMTATSGPGFSLIQEVIGYAIMTETPCVFANVMRLGPSTGLPTKPAQGDIMQ 127 Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191 + WGTHGDH++I L PS+V E + + I AFNLAE+YRTPV+ L DA +GHMRE Y P+ Sbjct: 128 TRWGTHGDHAIIALYPSSVAEVYRYIITAFNLAEEYRTPVVFLMDAMLGHMRESFYPPKD 187 Query: 192 DEIEIVNRKLPQN--EEEAKLPFGDPHGDFVPPMPIFGRG-YRTYVTGLTHDERGRPRTV 248 +E+ I+ R + EE+ +PF + P P+ G + +V+GL HDE G P + Sbjct: 188 EELFIIERLKDTSFGEEDLFVPFSESEYAEPTPFPMAEMGKTKFHVSGLVHDESGFPLS- 246 Query: 249 EREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGI 308 + E++IRR+ KI + +I YE E +DAE+ +V GIVARSA++A+K R I Sbjct: 247 SPDAAEKLIRRLTNKIRLHADEIAFYEEYETEDAEILVVAYGIVARSAMKAVKIARRDRI 306 Query: 309 KAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV-KLISKIG 367 K GL K TIWP K+A KV I + EMNLGQ + + +++V + I+K+ Sbjct: 307 KVGLFKPITIWPAPVSRFRKLAEKVNTIVIAEMNLGQYAKELISSIDRRSKVIRTINKVN 366 Query: 368 GEVHTPMEIVDFI 380 GE+ P EI+D I Sbjct: 367 GELIKPEEILDVI 379 >pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain Cj0536 [similarity] - Campylobacter jejuni (strain NCTC 11168) >gi|6968004|emb|CAB75172.1| (AL139075) OORA subunit of 2-oxoglutarate:acceptor oxidoreductase [Campylobacter jejuni] Length = 374 Score = 294 bits (745), Expect = 1e-78 Identities = 157/369 (42%), Positives = 233/369 (62%), Gaps = 3/369 (0%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIGAS 74 G+ IA+AAI GC+F+ GYPITP+SEI ++ +P DG IQMEDEI+ I+ IGA+ Sbjct: 8 GNVLIAKAAIDCGCKFFGGYPITPSSEIAHELSHMLPANDGTFIQMEDEISGISVAIGAA 67 Query: 75 WAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIW 134 +G K+MTA+SGPG SL E IG A + E P+V+V+V RGGPSTG PT +QGD+ Q+ Sbjct: 68 MSGVKSMTASSGPGISLKAEQIGLAFIAEIPLVIVNVMRGGPSTGLPTRVAQGDLFQAKA 127 Query: 135 GTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194 THGD + I ++P++++EA+ TIRAFNLAEKY TPV LL D VGHM + +P+ +I Sbjct: 128 PTHGDFASIAIAPASLEEAYTETIRAFNLAEKYMTPVFLLMDETVGHMNGKAVLPDLKDI 187 Query: 195 EIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREVHE 254 ++ NRK + +++ P+ + P F GYR +VTGL H + G P T + + + Sbjct: 188 KVYNRKKFEGDKKDYKPYAAGENEPATLNPFF-TGYRYHVTGLHHGDIGFP-TEDGVIVK 245 Query: 255 RVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAGLLK 314 + + R++ KI+ N++DI YE LDDAE I+ G V+RSA AI+ LRE GIK GL + Sbjct: 246 KNMERLIGKIKNNQEDICTYEEYMLDDAEFLIIAYGSVSRSAKEAIQRLREQGIKVGLFR 305 Query: 315 INTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVHTPM 374 T++P + I ++ K +++ V E+N+GQ + E + + + + G TP Sbjct: 306 PITLYPVAEKKIAEVVSKFKKVMVSELNMGQYLEEI-ERVTSRRDFISLHRANGRPITPS 364 Query: 375 EIVDFIRRD 383 EI+ ++ + Sbjct: 365 EIIAKVKEN 373 >gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA) [Archaeoglobus fulgidus] >gi|6685587|sp|O29781|KORA_ARCFU 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7433685|pir||E69308 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain korA - Archaeoglobus fulgidus >gi|2650159|gb|AAB90768.1| (AE001072) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA) [Archaeoglobus fulgidus] Length = 346 Score = 278 bits (704), Expect = 7e-74 Identities = 153/336 (45%), Positives = 209/336 (61%), Gaps = 28/336 (8%) Query: 11 DFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAI 70 + IQG+EA R AI AGC F+AGYPITP+SEI MA +P GV IQMEDEIASI+A+ Sbjct: 4 ELIQGNEAAVRGAINAGCNFFAGYPITPSSEIAHGMAELLPKFGGVFIQMEDEIASISAV 63 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 IGAS AGA AMTATSGPGFSLMQE +GYA +TE+P+V+ +V R GPSTG PT PSQGD M Sbjct: 64 IGASMAGAVAMTATSGPGFSLMQEGMGYAAITESPVVIFNVMRAGPSTGIPTAPSQGDAM 123 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE 190 Q+ +G+HGD+ ++VL+P++V++ + T+ AF +A ++ TPVI+LSD VGHMRE V +P Sbjct: 124 QARYGSHGDYPIVVLAPASVKDMYYLTVEAFKIAFRFSTPVIVLSDEIVGHMRESVALPP 183 Query: 191 PDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVER 250 EIE ++ + G R + TGL H E G P T + Sbjct: 184 LGEIESYEKRAKNLID----------------------GRRRHRTGLVHTENGLP-TTDL 220 Query: 251 EVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKA 310 E +E+++R + K D F R + V V G R A + K L E G+ A Sbjct: 221 EEYEKLLRLLFAKF-----DDFRPMVRFEGEEGVLFVAYGSSYRLAKSSAKLLAEKGVSA 275 Query: 311 GLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQL 346 G+LK+ +++PF + + + + K + + VPEMN GQ+ Sbjct: 276 GILKLESLFPFPEDAVRRYSKKADLVVVPEMNAGQV 311 >pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Helicobacter pylori (strain 26695) >gi|2313707|gb|AAD07654.1| (AE000572) ferredoxin oxidoreductase, alpha subunit [Helicobacter pylori 26695] Length = 375 Score = 261 bits (660), Expect = 1e-68 Identities = 145/366 (39%), Positives = 217/366 (58%), Gaps = 7/366 (1%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIGAS 74 G+E +A+AAI GCRF+ GYPITP+S+I AM++ +P G IQMEDEI+ I+ +GAS Sbjct: 8 GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPKCGGHFIQMEDEISGISVSLGAS 67 Query: 75 WAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIW 134 +G K+MTA+SGPG SL E IGY+ M E P+V+ DV R GPSTG PT +QGD+ Sbjct: 68 MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVAQGDVNFLRH 127 Query: 135 GTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194 HGD + L+P+ ++EA+ T+RAFNLAE TPV LL D VGHM +V IP+ +E+ Sbjct: 128 PIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187 Query: 195 E--IVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREV 252 + +NRK +++ P+G + P F +GYR +V+GL H G P T + ++ Sbjct: 188 QKMTINRKEFLGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGFP-TEDAKI 245 Query: 253 HERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL-RELGIKAG 311 +I R+ KIE + I + E +L+ AE+ ++ G V+ + A+K+ +E K G Sbjct: 246 GGDLIDRLFNKIESKQDIINENEEMDLEGAEIVVIAYGSVSLAVKEALKDYHKESKQKVG 305 Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371 + T+WP + +++I K E+I V E+N GQ + K V + + G Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLEEIERAMQRK--VHFLGQANGRTI 363 Query: 372 TPMEIV 377 +P +I+ Sbjct: 364 SPKQII 369 >pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacter pylori (strain J99) >gi|4155084|gb|AAD06119.1| (AE001486) SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCTASE [Helicobacter pylori J99] Length = 375 Score = 258 bits (653), Expect = 7e-68 Identities = 145/366 (39%), Positives = 215/366 (58%), Gaps = 7/366 (1%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIGAS 74 G+E +A+AAI GCRF+ GYPITP+S+I AM++ +P G IQMEDEI+ I+ +GAS Sbjct: 8 GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPKCGGHFIQMEDEISGISVSLGAS 67 Query: 75 WAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIW 134 +G K+MTA+SGPG SL E IGY+ M E P+V+ DV R GPSTG PT +QGD+ Sbjct: 68 MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVAQGDVNFLRH 127 Query: 135 GTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194 HGD + L+P+ ++EA+ T+RAFNLAE TPV LL D VGHM +V IP+ +E+ Sbjct: 128 PIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187 Query: 195 E--IVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREV 252 + +NRK +++ P+G + P F +GYR +V+GL H G P T + ++ Sbjct: 188 QKMTINRKEFAGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGFP-TEDAKI 245 Query: 253 HERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL-RELGIKAG 311 +I R+ KIE + I + E +L+ E+ I+ G V+ + A+K+ +E K G Sbjct: 246 GGDLIDRLFHKIESKQDIINENEEMDLEGTEIVIIAYGSVSLAVKEALKDYNKESKQKVG 305 Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371 + T+WP + +++I K E+I V E+N GQ + K V + G Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLEEIERVMQRK--VHFFGQANGRTI 363 Query: 372 TPMEIV 377 +P +I+ Sbjct: 364 SPKQII 369 >gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:acceptor oxidoreductase [Helicobacter pylori] Length = 371 Score = 256 bits (647), Expect = 3e-67 Identities = 141/334 (42%), Positives = 205/334 (61%), Gaps = 5/334 (1%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIGAS 74 G+E +A+AAI GCRF+ GYPITP+S+I AM++ +P G IQMEDEI+ I+ +GAS Sbjct: 8 GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPNCGGHFIQMEDEISGISVSLGAS 67 Query: 75 WAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIW 134 +G K+MTA+SGPG SL E IGY+ M E P+V+ DV R GPSTG PT QGD+ Sbjct: 68 MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVDQGDVNFLRH 127 Query: 135 GTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194 HGD + L+P++++EA+ T RAFNLAE TPV LL D VGHM +V IP+ +E+ Sbjct: 128 PIHGDFKAVALAPASLEEAYTETARAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187 Query: 195 E--IVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREV 252 + +NRK +++ P+G + P F +GYR +V+GL H G P T + ++ Sbjct: 188 QKTTINRKEFVGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGFP-TEDAKI 245 Query: 253 HERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL-RELGIKAG 311 +I R+ KIE + I + E +L+ AE+ I+ G V+ + A+K+ +E K G Sbjct: 246 GGDLIDRLFNKIESKQDIINENEEMDLEGAEIVIIAYGSVSLAVKEALKDYHKESNQKVG 305 Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQ 345 + T+WP + +++I K E+I V E+N GQ Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQ 339 >pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (strain MSB8) >gi|4982338|gb|AAD36824.1|AE001814_6 (AE001814) 2-oxoisovalerate oxidoreductase, beta subunit, putative [Thermotoga maritima] Length = 356 Score = 240 bits (605), Expect = 3e-62 Identities = 148/366 (40%), Positives = 203/366 (55%), Gaps = 29/366 (7%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72 ++G+EAIA +AI AGCR Y YPITP SEI E MA +P V GV +Q E EIA++ + G Sbjct: 9 MKGNEAIAESAIRAGCRLYFAYPITPQSEIAEYMARRLPEVGGVFLQTESEIATVNMVYG 68 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A+ G + MT+TS PGFSLMQE I Y E P V VDV RGGP G PSQGD Q+ Sbjct: 69 AACTGKRVMTSTSSPGFSLMQEGISYIAGAELPCVFVDVVRGGPGLGN-IQPSQGDYFQA 127 Query: 133 I-WGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191 + G HGD+ LIVL+PST+QEA D T AF+LA++YR PV++L+D +G M E V +PE Sbjct: 128 VKGGGHGDYRLIVLAPSTLQEAVDLTQLAFDLADRYRNPVLILADGMIGQMMEPVELPEM 187 Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251 ++ LP + + A RG R R ++ Sbjct: 188 RDLST----LPDHSDWAL------------------RGARN-----REPHRIAAFNIDPV 220 Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311 E++ +R+ EK + +E +D AE +V G + R + LRE GI AG Sbjct: 221 GLEKMNKRLQEKYRLIEASEQRWEEYRVDGAEYLMVGYGTMGRILKSVVDSLREEGIPAG 280 Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371 L + T+WPF ++++A KV+ I+V EM+ GQ+ V+ GK V ++GG V Sbjct: 281 LFRPVTLWPFPKRRLKELAKKVQLIFVVEMSSGQMVEDVQISVEGKVPVHFYGRMGGVVP 340 Query: 372 TPMEIV 377 TP EI+ Sbjct: 341 TPEEIL 346 >dbj|BAB06093.1| (AP001515) pyruvate synthase alpha subunit [Bacillus halodurans] Length = 579 Score = 210 bits (528), Expect = 3e-53 Identities = 138/380 (36%), Positives = 207/380 (54%), Gaps = 16/380 (4%) Query: 9 KADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIA 68 K F+ G++AI A+ AG RF A YPITPASEI E + +P G VIQ EDEIA+ Sbjct: 196 KRMFMIGNDAIGMGAVAAGSRFMAAYPITPASEIMEYLIKKLPEFGGAVIQTEDEIAACT 255 Query: 69 AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128 IGA++AG ++ TA++GPG SLM E IG + MTETP+V+VD QRGGPS G PT Q D Sbjct: 256 MAIGANYAGVRSFTASAGPGLSLMAEAIGLSGMTETPLVIVDTQRGGPSIGLPTKQEQSD 315 Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188 +M I+ THGD +V++PSTV+EAF T+ AFN+AE+Y+ PVIL++D + ++ V Sbjct: 316 LMAMIYSTHGDIPKVVMAPSTVEEAFYDTVEAFNIAEEYQCPVILVTDLALSLGKQTVEP 375 Query: 189 PEPDEIEIVNRKLPQNEEEAKLPFGDPHGDF------VPPMPIFG-RGYRTYVTGLTHDE 241 + ++EI L ++ + G+ + + V P + G + +VTG+ HD+ Sbjct: 376 LDFSKVEIRRGSLQNEDQLTEQEKGEYYKRYELTETGVSPRVLPGQKNGIHHVTGVEHDQ 435 Query: 242 RGRP---RTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSAL- 297 G+P T E E+ +R++ ER + + E D V + + R A+ Sbjct: 436 TGKPSESATNRIEQMEKRLRKVEALPERFPTPVHIHAPHEEPDLLVIGINS---TRGAIE 492 Query: 298 RAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVREGANG 356 AI L I+ I + PF ++ K +++ V E N QL L++ + Sbjct: 493 EAIPRLEADSIRVNHAHIRLVHPFPKHELQPYLTKAKKVVVVEHNATAQLASLIKMNCDV 552 Query: 357 KAEVKLISKIGGEVHTPMEI 376 KA ++ + + G P EI Sbjct: 553 KA-IENVLRYDGNPFLPGEI 571 >gb|AAG19013.1| (AE005001) pyruvate ferredoxin oxidoreductase, subunit alpha; PorA [Halobacterium sp. NRC-1] Length = 582 Score = 202 bits (509), Expect = 5e-51 Identities = 123/304 (40%), Positives = 173/304 (56%), Gaps = 16/304 (5%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72 + GDEAI AI AGCRFYAGYPITPA+++ E + + G V+Q EDE+A+I +G Sbjct: 202 LNGDEAIGMGAIAAGCRFYAGYPITPATDVMEYLTGRIEQFGGHVVQAEDELAAINLALG 261 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A+ AGA++MTATSGPG LM E G +ETP+V+ +V R GPSTG PT QGD+ Sbjct: 262 AARAGARSMTATSGPGIDLMSETFGLVATSETPLVIANVMRSGPSTGMPTKQEQGDLNMM 321 Query: 133 IWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP- 191 + G HG+ V++P++V E F T+ AFNLAEKY+ PV + +D + + ER Y PE Sbjct: 322 LKGGHGEIPRFVVAPTSVAECFHKTVEAFNLAEKYQLPVYVTADLSMA-VTERTYPPEEF 380 Query: 192 --DEIEIVNRKLP--------QNEEEAKLPFGDPHGDFVPPMPIFG-RGYRTYVTGLTHD 240 D +EI KL QN+ E P D D + P + G G TGL HD Sbjct: 381 DMDAVEIERGKLVDEDEISAWQNDTEQFRPHADT-ADGISPRAVPGTEGGVHMSTGLEHD 439 Query: 241 ERGRPRTVEREVHERVIRRIVEKIE-RNKKDIFDYEARELDDAEVAIVTTGIVARSALRA 299 E GR RT + +V + + K++ +++ FDY DA+ +V+ G + + A Sbjct: 440 ELGR-RTEDTDVRVDQVDKRYRKVDTAREREQFDYREFGDSDADNLVVSWGSNEGTIVEA 498 Query: 300 IKEL 303 ++ L Sbjct: 499 LEYL 502 >pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621790|gb|AAB85209.1| (AE000849) 2-oxoisovalerate oxidoreductase, beta subunit [Methanobacterium thermoautotrophicum] Length = 348 Score = 196 bits (494), Expect = 3e-49 Identities = 136/378 (35%), Positives = 198/378 (51%), Gaps = 48/378 (12%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72 ++G+ A+ A+ AGC Y GYPITPASEI + Y P+V +Q E E A+I + G Sbjct: 2 VKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYG 61 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A+ AG + MTA+SGPG SL QE I + E P V+VDV R GP G P QGD Q Sbjct: 62 AAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGN-IGPEQGDYNQI 120 Query: 133 I-WGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE- 190 + G HG++ +VL+PS+VQE D T+ AF LA+KYR PV++L+DA +G M E + PE Sbjct: 121 VKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPEE 180 Query: 191 -----PDEIEIV--NRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERG 243 PD V NR+ +N VT + D Sbjct: 181 AVEHRPDTSWAVCGNRETMKN----------------------------LVTSIFLD--- 209 Query: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303 E E ++ +IE N+ YE +DDAE+ +V GI +R A A++ Sbjct: 210 ---FDELEEFNFYLQEKYARIEENE---VRYEEYLVDDAEIVMVAYGISSRVARSAVETA 263 Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLI 363 R GI GLL+ T++PF + I ++A R EM+ GQ+ +R A+G +V+L+ Sbjct: 264 RAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDIRM-ASGCRDVELV 322 Query: 364 SKIGGEVHTPMEIVDFIR 381 +++GG + ++++ IR Sbjct: 323 NRMGGNLIELRDVLEKIR 340 >sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE BETA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) Length = 352 Score = 196 bits (494), Expect = 3e-49 Identities = 136/378 (35%), Positives = 198/378 (51%), Gaps = 48/378 (12%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72 ++G+ A+ A+ AGC Y GYPITPASEI + Y P+V +Q E E A+I + G Sbjct: 6 VKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYG 65 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A+ AG + MTA+SGPG SL QE I + E P V+VDV R GP G P QGD Q Sbjct: 66 AAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGN-IGPEQGDYNQI 124 Query: 133 I-WGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE- 190 + G HG++ +VL+PS+VQE D T+ AF LA+KYR PV++L+DA +G M E + PE Sbjct: 125 VKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPEE 184 Query: 191 -----PDEIEIV--NRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERG 243 PD V NR+ +N VT + D Sbjct: 185 AVEHRPDTSWAVCGNRETMKN----------------------------LVTSIFLD--- 213 Query: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303 E E ++ +IE N+ YE +DDAE+ +V GI +R A A++ Sbjct: 214 ---FDELEEFNFYLQEKYARIEENE---VRYEEYLVDDAEIVMVAYGISSRVARSAVETA 267 Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLI 363 R GI GLL+ T++PF + I ++A R EM+ GQ+ +R A+G +V+L+ Sbjct: 268 RAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDIRM-ASGCRDVELV 326 Query: 364 SKIGGEVHTPMEIVDFIR 381 +++GG + ++++ IR Sbjct: 327 NRMGGNLIELRDVLEKIR 344 >pir||A72519 probable 2-oxoacid--ferredoxin oxidoreductase alpha chain APE2126 - Aeropyrum pernix (strain K1) >gi|5105825|dbj|BAA81137.1| (AP000063) 644aa long hypothetical 2-oxoacid--ferredoxin oxidoreductase alpha chain [Aeropyrum pernix] Length = 644 Score = 186 bits (467), Expect = 4e-46 Identities = 129/359 (35%), Positives = 192/359 (52%), Gaps = 35/359 (9%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL-VDG------VVIQMEDEIASI 67 G++ +A ++ G R+ A YPITPAS+ + + L +DG ++Q EDEIA++ Sbjct: 252 GNDVVAMGKVVGGVRYQAYYPITPASDESVLLEEFEGLKIDGESLGSIAILQTEDEIAAV 311 Query: 68 AAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQG 127 +++IGA+ GA+A TATSGPGFSLM E +G+A + P+V+ QRGGPSTG PT SQ Sbjct: 312 SSVIGAALTGARASTATSGPGFSLMVEALGWAGKNDVPMVITYYQRGGPSTGLPTRGSQS 371 Query: 128 DIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVY 187 D++ S++ +HG+ I+LS EAF I A+NLAE+++ PVI L D + +M V Sbjct: 372 DLLFSLFASHGEFPRIILSSGDHLEAFYDAIEAYNLAERFQMPVIHLLDKFLANMVASVP 431 Query: 188 IPEPDEIEIVNRKLPQNEEEAKLPFGD----PHGDFVPPMPIFGRGYRTYVTGLTHDERG 243 P+ I K+ + + K P G P + P+ G G T+ TG +DE G Sbjct: 432 FPDWKAI-----KIDRGKTLFKAPTGPFKRFPRDQPLADRPVLGSGAITWYTGDENDEYG 486 Query: 244 RPRTVEREVHERVIRRIVEKIERNKK-DIFDYEARE--------LDDAEVAIVTTGIVAR 294 + E + R+V R KK +I D E E +DAEV +V G V Sbjct: 487 -------HIDEDPVNRLVMYERRWKKMEIADREIPEDFRVKYYGDEDAEVLLVGWGSVKI 539 Query: 295 SALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGK--VERIYVPEMN-LGQLYHLV 350 AL AI+ LRE+G+ A L + + P + ++ + +R+ E N LGQ +V Sbjct: 540 PALEAIERLREMGVNAAYLHLRMLSPLPKRRVSEVLSRFDADRVIAVEANYLGQASKIV 598 >pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha chain APE1473 - Aeropyrum pernix (strain K1) >gi|5105157|dbj|BAA80471.1| (AP000061) 616aa long hypothetical 2-oxoacid--ferredoxin oxidoreductase , alpha chain [Aeropyrum pernix] Length = 616 Score = 184 bits (463), Expect = 1e-45 Identities = 139/398 (34%), Positives = 206/398 (50%), Gaps = 44/398 (11%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL-----VDG-------------V 56 G++ +A I+ G YPITP+S+ ALY+ +DG Sbjct: 218 GNDLVAMGKIVGGLGVITYYPITPSSD----EALYVEKHSYISIDGPLAEKLGYDKIAVA 273 Query: 57 VIQMEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGP 116 ++QMEDE+ASI A++GA+ AGA+A T TSGPGFSLM E + AV E P+VV R GP Sbjct: 274 IVQMEDELASINAVLGAAAAGARASTTTSGPGFSLMNEAVSLAVEAEIPVVVTLWMRAGP 333 Query: 117 STGQPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSD 176 STG PT Q D++ SI+ HGD IVL+ EAF I+AFN AE+++TPVI L D Sbjct: 334 STGMPTRTGQQDLLHSIFSGHGDAPKIVLASGDHVEAFYDAIKAFNWAEEFQTPVIHLLD 393 Query: 177 -----AEVGHMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYR 231 + V RE + +P ++ I KL N A + D + P G Sbjct: 394 KYLASSMVSLAREDL---DPSKVPITRGKLLDN-PPADYRRYEVVEDGISPRARLGSA-T 448 Query: 232 TYVTGLTHDERG--RPRTVEREV----HERVIRRIVEKIERNKKDIFDYEARELDDAEVA 285 +TGL HDE G V RE+ ER + I E+I +K + ++ +A VA Sbjct: 449 MVITGLEHDEYGYATEDPVMREIMMFKRERKFKVIEERIPDEEKAVLHGDS----EASVA 504 Query: 286 IVTTGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LG 344 +V+ G + L A++ LR+ G++A ++ ++PF L+E++ VE++ + E N LG Sbjct: 505 LVSFGSTKQPILEALEMLRDEGVRARFAQVRLLYPFPGRLVEEMLEGVEKVIMVEQNLLG 564 Query: 345 QLYHLVREGANGKAEVKLISKIGGEVHTPMEIVDFIRR 382 QL L+R + K + ++ KI G E+ ++R Sbjct: 565 QLAMLLRAHTSIKPDSSIV-KINGRPLYSFEVAGAVKR 601 >pir||S22396 pyruvate synthase (EC 1.2.7.1) alpha chain [validated] - Halobacterium salinarum >gi|43498|emb|CAA45825.1| (X64521) pyruvate synthase [Halobacterium halobium] Length = 628 Score = 176 bits (442), Expect = 4e-43 Identities = 127/397 (31%), Positives = 192/397 (47%), Gaps = 25/397 (6%) Query: 6 PVGKAD----FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQME 61 P G D + G AIA AI AGCRF +GYP+TP ++ F M +P + GV Q+E Sbjct: 212 PTGSHDEPQVLMSGSHAIAYGAIDAGCRFISGYPMTPWTDAFTIMTQLLPDMGGVSEQVE 271 Query: 62 DEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQP 121 DEIA+ A +GAS AGAKAM+ +SG GF+LM E +G A MTETP+V+++ QR GPSTG P Sbjct: 272 DEIAAAAMAVGASHAGAKAMSGSSGGGFALMSEPLGLAEMTETPLVLLEAQRAGPSTGMP 331 Query: 122 TLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGH 181 T P Q D+ ++ + GD + P +E ++ T AF +A Y+ PVILL D ++ Sbjct: 332 TKPEQADLEHVLYTSQGDSHRVAFGPKDPKECYEQTRTAFEIAYDYQIPVILLYDQKLSG 391 Query: 182 MRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHG----------DFVPPMPIFGR-GY 230 V D + +E++ DP G D V P I G+ G Sbjct: 392 EYRNVDASFFDREPAADLGTTLSEDQIPDAPHDPTGKYHRYQHDVEDGVSPRTIPGQSGG 451 Query: 231 RTYVTGLTHDERGRPRTVEREVHERV--IRRIVEKIERNKKDIFDYEAREL---DDAEVA 285 R +G H G + + RV + R ++K+ + D+ + + + +DA++ Sbjct: 452 RYLASGNEHWPNGH---ISEDTDNRVAQVERRLQKLAAIRDDLDERDQQTHYGDEDADIG 508 Query: 286 IVTTGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQ 345 ++ G + A+ L + G L I+ + PF V+ V EM+ + Sbjct: 509 LIAWGSQEGTVEEAVHRLNDDGNSVKALGISDLAPFPVAETRAFVDSVDEAIVVEMSSTK 568 Query: 346 LYHLVREGANGKAEVKLIS--KIGGEVHTPMEIVDFI 380 + + + G KL S K G P EIV+ + Sbjct: 569 QFRGLIQKEVGDIGGKLSSLLKYNGNPFEPAEIVEAV 605 >gb|AAG19514.1| (AE005043) putative 2-ketoglutarate ferredoxin oxidoreductase (alpha); KorA [Halobacterium sp. NRC-1] Length = 640 Score = 176 bits (442), Expect = 4e-43 Identities = 127/397 (31%), Positives = 192/397 (47%), Gaps = 25/397 (6%) Query: 6 PVGKAD----FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQME 61 P G D + G AIA AI AGCRF +GYP+TP ++ F M +P + GV Q+E Sbjct: 224 PTGSHDEPQVLMSGSHAIAYGAIDAGCRFISGYPMTPWTDAFTIMTQLLPDMGGVSEQVE 283 Query: 62 DEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQP 121 DEIA+ A +GAS AGAKAM+ +SG GF+LM E +G A MTETP+V+++ QR GPSTG P Sbjct: 284 DEIAAAAMAVGASHAGAKAMSGSSGGGFALMSEPLGLAEMTETPLVLLEAQRAGPSTGMP 343 Query: 122 TLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGH 181 T P Q D+ ++ + GD + P +E ++ T AF +A Y+ PVILL D ++ Sbjct: 344 TKPEQADLEHVLYTSQGDSHRVAFGPKDPKECYEQTRTAFEIAYDYQIPVILLYDQKLSG 403 Query: 182 MRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHG----------DFVPPMPIFGR-GY 230 V D + +E++ DP G D V P I G+ G Sbjct: 404 EYRNVDASFFDREPAADLGTTLSEDQIPDAPHDPTGKYHRYQHDVEDGVSPRTIPGQSGG 463 Query: 231 RTYVTGLTHDERGRPRTVEREVHERV--IRRIVEKIERNKKDIFDYEAREL---DDAEVA 285 R +G H G + + RV + R ++K+ + D+ + + + +DA++ Sbjct: 464 RYLASGNEHWPNGH---ISEDTDNRVAQVERRLQKLAAIRDDLDERDQQTHYGDEDADIG 520 Query: 286 IVTTGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQ 345 ++ G + A+ L + G L I+ + PF V+ V EM+ + Sbjct: 521 LIAWGSQEGTVEEAVHRLNDDGNSVKALGISDLAPFPVAETRAFVDSVDEAIVVEMSSTK 580 Query: 346 LYHLVREGANGKAEVKLIS--KIGGEVHTPMEIVDFI 380 + + + G KL S K G P EIV+ + Sbjct: 581 QFRGLIQKEVGDIGGKLSSLLKYNGNPFEPAEIVEAV 617 >emb|CAB60189.1| (AL132824) putative oxidoreductase alpha-subunit [Streptomyces coelicolor] Length = 630 Score = 175 bits (438), Expect = 1e-42 Identities = 124/362 (34%), Positives = 184/362 (50%), Gaps = 21/362 (5%) Query: 5 FPVGKADFIQGDEAIARAAILAGCR-----FYAGYPITPASEIFEAMALYMPLVDGV-VI 58 FP G I G+ A+A I A R F YPITPAS+I ++ + GV Sbjct: 242 FPPGTYRNISGNLALAYGLIAASRRADLPLFLGSYPITPASDILHELSKHKNF--GVRTF 299 Query: 59 QMEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPST 118 Q EDEIA I A +GA++ GA A+T TSGPG +L E IG AV E P++VVD+QRGGPST Sbjct: 300 QAEDEIAGIGAALGAAFGGALAVTTTSGPGVALKSETIGLAVSLELPLLVVDIQRGGPST 359 Query: 119 GQPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAE 178 G PT Q D++Q+++G +G+ + VL+P T + FD + A +A YRTPV LLSD Sbjct: 360 GLPTKTEQADLLQAMFGRNGEAPVAVLAPQTAADCFDAALEAARIALAYRTPVFLLSDGY 419 Query: 179 VGHMRERVYIPEPDEIEIVNRKLPQ-------NEEEAKLPF-GDPHGDFVPPMPIFGR-G 229 + + E IPEPDE+ + + Q + E P+ DPH P + G G Sbjct: 420 LANGSEPWRIPEPDELPDLTVQFAQGPNHTLDDGSEVFWPYKRDPH-TLARPWAVPGTPG 478 Query: 230 YRTYVTGLTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTT 289 + G+ + + + H+ ++R KI+ + D + D A ++ Sbjct: 479 LEHRIGGIEKQDGTGNISYDPANHDFMVRTRQAKID--GITVPDLAVDDPDGARTLVLGW 536 Query: 290 GIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHL 349 G A++ +R+ + + + PF L + + +++ VPEMNLGQL L Sbjct: 537 GSTYGPITAAVRRIRKEVGQIAQAHLRHLNPFPANL-GAVLERYDKVVVPEMNLGQLATL 595 Query: 350 VR 351 +R Sbjct: 596 IR 597 >emb|CAC08296.1| (AL392148) putative oxidoreductase [Streptomyces coelicolor] Length = 645 Score = 175 bits (438), Expect = 1e-42 Identities = 124/362 (34%), Positives = 184/362 (50%), Gaps = 21/362 (5%) Query: 5 FPVGKADFIQGDEAIARAAILAGCR-----FYAGYPITPASEIFEAMALYMPLVDGV-VI 58 FP G I G+ A+A I A R F YPITPAS+I ++ + GV Sbjct: 257 FPPGTYRNISGNLALAYGLIAASRRADLPLFLGSYPITPASDILHELSKHKNF--GVRTF 314 Query: 59 QMEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPST 118 Q EDEIA I A +GA++ GA A+T TSGPG +L E IG AV E P++VVD+QRGGPST Sbjct: 315 QAEDEIAGIGAALGAAFGGALAVTTTSGPGVALKSETIGLAVSLELPLLVVDIQRGGPST 374 Query: 119 GQPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAE 178 G PT Q D++Q+++G +G+ + VL+P T + FD + A +A YRTPV LLSD Sbjct: 375 GLPTKTEQADLLQAMFGRNGEAPVAVLAPQTAADCFDAALEAARIALAYRTPVFLLSDGY 434 Query: 179 VGHMRERVYIPEPDEIEIVNRKLPQ-------NEEEAKLPF-GDPHGDFVPPMPIFGR-G 229 + + E IPEPDE+ + + Q + E P+ DPH P + G G Sbjct: 435 LANGSEPWRIPEPDELPDLTVQFAQGPNHTLDDGSEVFWPYKRDPH-TLARPWAVPGTPG 493 Query: 230 YRTYVTGLTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTT 289 + G+ + + + H+ ++R KI+ + D + D A ++ Sbjct: 494 LEHRIGGIEKQDGTGNISYDPANHDFMVRTRQAKID--GITVPDLAVDDPDGARTLVLGW 551 Query: 290 GIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHL 349 G A++ +R+ + + + PF L + + +++ VPEMNLGQL L Sbjct: 552 GSTYGPITAAVRRIRKEVGQIAQAHLRHLNPFPANL-GAVLERYDKVVVPEMNLGQLATL 610 Query: 350 VR 351 +R Sbjct: 611 IR 612 >pir||F70864 probable oxidoreductase alpha subunit - Mycobacterium tuberculosis (strain H37RV) >gi|2791495|emb|CAA16032.1| (AL021246) hypothetical protein Rv2455c [Mycobacterium tuberculosis] Length = 653 Score = 169 bits (424), Expect = 5e-41 Identities = 123/385 (31%), Positives = 191/385 (48%), Gaps = 18/385 (4%) Query: 6 PVGKADFIQGDEAIARAAILAGCR-----FYAGYPITPASEIFEAMALYMPLVDGVVIQM 60 P G+ I G+ A+A ++AG YPITPAS+I ++ + + V Q Sbjct: 247 PPGEYRQISGNTALAYGIVVAGQLAGLPVVLGSYPITPASDILHELSKHKNF-NVVTFQA 305 Query: 61 EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120 EDEI I A +GA++ GA +T+TSGPG SL E +G VMTE P++V+DVQRGGPSTG Sbjct: 306 EDEIGGICAALGAAYGGALGVTSTSGPGISLKSEALGLGVMTELPLLVIDVQRGGPSTGL 365 Query: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180 PT Q D++Q+++G +G+ + VL+P + + F+ + A +A Y TPVILLSD + Sbjct: 366 PTKTEQADLLQALYGRNGESPVAVLAPRSPADCFETALEAVRIAVSYHTPVILLSDGAIA 425 Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGR-GYRTYVTGLTH 239 + E IP+ + + + + E + P+ I G G + GL Sbjct: 426 NGSEPWRIPDVNALPPIKHTFAKPGEPFQ-PYARDRETLARQFAIPGTPGLEHRIGGLEA 484 Query: 240 DERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARE-LDDAEVAIVTTGIVARSALR 298 + E H+ ++R KI+ + D E + DAE+ ++ G Sbjct: 485 ANGSGDISYEPTNHDLMVRLRQAKID--GIHVPDLEVDDPTGDAELLLIGWGSSYGPIGE 542 Query: 299 AIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGK- 357 A + R G K + + PF L E + + ++ PE+NLGQL ++R GK Sbjct: 543 ACRRARRRGTKVAHAHLRYLNPFPANLGE-VLRRYPKVVAPELNLGQLAQVLR----GKY 597 Query: 358 -AEVKLISKIGGEVHTPMEIVDFIR 381 +V+ ++K+ G EI FIR Sbjct: 598 LVDVQSVTKVKGVSFLADEIGRFIR 622 >emb|CAC11404.1| (AL445063) probable pyruvate ferredoxin oxidoreductase, alpha subunit [Thermoplasma acidophilum] Length = 588 Score = 167 bits (419), Expect = 2e-40 Identities = 115/381 (30%), Positives = 189/381 (49%), Gaps = 9/381 (2%) Query: 5 FPVGKADF-IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDE 63 F GK + I G A+A A+ G + Y YP+TPAS +A + V EDE Sbjct: 199 FKFGKKKYMISGGMAVALGAVAGGLKMYVAYPMTPASSALHFLAQHAKKYGVFVKIPEDE 258 Query: 64 IASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTL 123 I++I +IGA++AG +AMT +SG GF+LM E +G + MTE P+V+ + QR GPSTG PT Sbjct: 259 ISAINTVIGANYAGVRAMTGSSGGGFALMTEAVGLSGMTEVPLVIYEAQRPGPSTGLPTK 318 Query: 124 PSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMR 183 QGD+ Q + + GD IV +P ++EAF T A N+AEKY+TPV ++SD + Sbjct: 319 TEQGDLNQVLGASQGDFPRIVFAPGDIEEAFYLTREAMNIAEKYQTPVFVMSDLYLAEHY 378 Query: 184 ERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGR-GYRTYVTGLTHDER 242 + + + + + NE++ K G + P I G+ G H+E Sbjct: 379 DTIDSFDLNFNIDHGLRAKDNEQDYKRYLITETG--ISPRAIPGQPGNMHNEDSDEHNEY 436 Query: 243 G---RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRA 299 G + +++++ + K++ +++ + DAE I+ G + A Sbjct: 437 GDVVSDAVTNPQDRIKMMQKRMRKLDTYIEEMKPTPTYRIQDAEYVIIQWGSTKGAVEEA 496 Query: 300 IKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAE 359 I LR GIK G +++ ++P + ++ + + + + V GQL + A + Sbjct: 497 IDILRAKGIKIGAIEVKNVFPLNPDIGTLLKNRKKILAVENNYSGQLSKYI--AAQFLVK 554 Query: 360 VKLISKIGGEVHTPMEIVDFI 380 +LI+K GE P + + I Sbjct: 555 PELITKYDGEAFYPNALAEEI 575 >emb|CAC11904.1| (AL445065) probable 2-oxoacid ferredoxin oxidoreductase, alpha chain [Thermoplasma acidophilum] Length = 629 Score = 167 bits (419), Expect = 2e-40 Identities = 113/353 (32%), Positives = 176/353 (49%), Gaps = 20/353 (5%) Query: 6 PVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEI------------FEAMALYMPLV 53 P + + G++A A +L G RF YPITPAS+ + A + Sbjct: 226 PTPRKLLLTGNDASALGKLLGGLRFQTYYPITPASDESTTIEEHQNIKWLDKEAANLKKG 285 Query: 54 DGVVIQMEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQR 113 V++Q EDE++++ IG + G ++ TATSGPGFSLM E + +A M E P+VV +R Sbjct: 286 GVVIVQTEDELSAVNMAIGGALTGVRSATATSGPGFSLMAEGLSFAGMDEVPLVVTFYER 345 Query: 114 GGPSTGQPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVIL 173 GGPSTG PT Q D++ ++ HG++ IV S TV E +A N A KY+ PVI Sbjct: 346 GGPSTGLPTRNGQSDLLFALNAGHGEYPRIVFSSGTVDECIYDAAKALNYAAKYQMPVIH 405 Query: 174 LSDAEVGHMRERVYIPEPDEIEIVNRKLPQNEEEAK-LPFGDPHGDFVPPMPIFGRGYRT 232 L D + + + + + D I+I KL + ++ K +G V P GR Sbjct: 406 LIDKNLANTLDLISKVDLDRIKIETVKLAKEGDDVKRYDLNTDNG--VSPYTTMGRNI-F 462 Query: 233 YVTGLTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEAREL---DDAEVAIVTT 289 ++TG HDE G T + ++ +R++ + +K+E ++I E L +A++ VT Sbjct: 463 WMTGDEHDELGHV-TEDSDIRDRMMEKRFKKLETADREIPIDEKAVLIGEKEADITFVTW 521 Query: 290 GIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342 G L I++L+E GI A LL + PF E ++ + + E N Sbjct: 522 GSQKGPILDVIEDLKEEGISANLLYLKMFSPFPTEFVKNVLSSANLVIDVESN 574 >gb|AAK42926.1| 2-oxoacid--ferredoxin oxidoreductase, alpha chain [Sulfolobus solfataricus] Length = 632 Score = 164 bits (412), Expect = 1e-39 Identities = 125/349 (35%), Positives = 176/349 (49%), Gaps = 23/349 (6%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASE--IFEAMALYMPLVDG----------VVIQM 60 + G+ A A I G RF + YPITPAS+ +F + VD VV+Q Sbjct: 233 LDGNTAAAIGKIYGGLRFQSYYPITPASDESVFIEAHQTVFTVDPKTGEKRKSTIVVVQA 292 Query: 61 EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120 EDE+A+I GA+ G +A TATSGPGFSLM E +G+A M E P+V+ RGGPSTGQ Sbjct: 293 EDELAAINMASGAALTGVRAATATSGPGFSLMVEGMGWAGMNEVPVVITYYIRGGPSTGQ 352 Query: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180 PT SQ D+M ++ HG+ IV++ EAF A NLA+KY+TPVI L D + Sbjct: 353 PTRTSQADLMFALNAGHGEFPRIVIASGDHVEAFHDGTWALNLAQKYQTPVIHLVDKALA 412 Query: 181 HMRERVYIPEP----DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTG 236 + IP+ + I I K+ N +L + D + P G R + TG Sbjct: 413 NSYS--IIPKKTLGMENIRIEKGKIVINTNTPELKRFEITEDGISPFAPLGTA-RVHYTG 469 Query: 237 LTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEAREL---DDAEVAIVTTGIVA 293 HDE G E E++ + ++K+ K+I + + D++VAI+T G Sbjct: 470 DEHDEYGFIAEAS-ENREKMYEKRIKKLMTADKEIPEESRVNVYGNTDSKVAIITWGSPK 528 Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342 + L A++EL GIK L++I PF L+ K+ E I E N Sbjct: 529 GAILDAMEELENEGIKPMLIQIRMFSPFPKNLMRKLLNGKEFIIDVESN 577 >pir||B72288 2-oxoacid ferredoxin oxidoreductase, alpha subunit - Thermotoga maritima (strain MSB8) >gi|4981713|gb|AAD36240.1|AE001773_9 (AE001773) 2-oxoacid ferredoxin oxidoreductase, alpha subunit [Thermotoga maritima] Length = 558 Score = 162 bits (405), Expect = 8e-39 Identities = 111/343 (32%), Positives = 178/343 (51%), Gaps = 13/343 (3%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72 + G EA+ AI GC F + YP++P++ + +A + VV Q EDEIA++ IIG Sbjct: 195 LNGAEAVGLGAIAGGCNFVSSYPMSPSTSVLVFLAQHKNDFGIVVEQAEDEIAAMNMIIG 254 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A +AGA+ + TSG GF+LM+E + A M E+P V+ QR GP+TG PT QGD+ + Sbjct: 255 AWYAGARGLVTTSGGGFALMEEALSLAGMIESPAVIHLAQRPGPATGLPTRTEQGDLNLA 314 Query: 133 IWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPD 192 ++ HGD ++ +P V+EAF T +AFN+A+KY+ PV +L+D + + + + Sbjct: 315 LYAGHGDFPRVIYAPGNVEEAFYLTQKAFNVADKYQVPVFVLTDQYLVDSYYNLPGFDLN 374 Query: 193 EIEIVNRKLPQNEEEAKLPFGDPHGDFVPP--MPIFGRGYRTYVTGLTHDERGRPRTVER 250 E+++ + + + + D + P +P +G G V HDE G T + Sbjct: 375 ELKVEKHFIKTTRDYIRYAITE---DGISPRGIPGYGEGL-VRVDSDEHDEFGH-ITEDF 429 Query: 251 EVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKA 310 R++ + + K E KK+I + ++ V +V G S L IKE E Sbjct: 430 NTRVRMVNKRLRKGETLKKEIVKPKLIGDENYRVLLVAWG----STLEPIKEAIEGLDGV 485 Query: 311 GLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVRE 352 LL + +WP D E + K E++ E N GQ +L+R+ Sbjct: 486 ALLHFSQVWPID-ESVATYFEKAEKVVAVEGNATGQFANLIRQ 527 >emb|CAA75641.1| (Y15464) ferredoxin oxidoreductase-like (gamma and alpha subunit in fusion) [Thermus thermophilus] Length = 617 Score = 152 bits (381), Expect = 5e-36 Identities = 116/372 (31%), Positives = 190/372 (50%), Gaps = 19/372 (5%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPASE--IFEAMALYMPLVDGVVIQMEDEIASIAA 69 ++ G +A A + G RF YPI+PA++ +F ++P D V+Q EDEIA++ Sbjct: 233 YLTGAQAAALGKLAGGLRFQTYYPISPATDESVFLEAHTHLPGADVAVVQTEDEIAAVNM 292 Query: 70 IIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDI 129 +GA+ AGAKA TATSGPGFSLM E +G+A M E P+VV QRG PT QGD+ Sbjct: 293 AVGAALAGAKAATATSGPGFSLMAEGLGFAGMIEAPLVVTLYQRGRAQHRLPTRTEQGDL 352 Query: 130 MQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIP 189 M +I G HG++ +VL+ + +AF +A A +Y+T V+ L D + + + + Sbjct: 353 MFAIRGGHGEYPRLVLASGDILDAFLDAQKALAWAWRYQTVVVHLLDKFLASLAQSL--- 409 Query: 190 EPDEIEIVN----RKLPQNEEEAKLPFGDPHGDFVPP-MPIFGRGYRTYVTGLTHDERGR 244 + +++++ ++L E P D + P +PI G ++T HD G Sbjct: 410 PKEALKVLSLDGEKRLSPREGFGPYQRYAPGEDGLSPFIPIGTPGGFYWMTSDEHDPLGH 469 Query: 245 PRTVEREVHERVIRRIVEKIERNKKDI-FDYEARELDDAEVAIVTTGIVARSALRAIKEL 303 T + E+ E + + +EK+E +K+I + + D EV ++ G V + L A+ L Sbjct: 470 -ITEDVELRELQMEKRMEKLELARKEIPLEDQYTLFRDGEVLVLGWGTVKGTLLEALDHL 528 Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLI 363 + G L + +WPF + + GK + V GQL LV++ + +++ Sbjct: 529 EGV----GYLHLRLLWPFP-RIAPLLEGKT-LVTVEHNYSGQLADLVQQETLKRVHHRVV 582 Query: 364 SKIGGEVHTPME 375 K G +P+E Sbjct: 583 -KYNGRAPSPLE 593 >pir||JC4919 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain [validated] - Sulfolobus sp. (strain 7) >gi|1565183|dbj|BAA10898.1| (D64024) 2-oxoacid:ferredoxin oxidoreductase subunit alpha [Sulfolobus sp. 7] Length = 632 Score = 152 bits (381), Expect = 5e-36 Identities = 126/380 (33%), Positives = 182/380 (47%), Gaps = 35/380 (9%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPAS------EIFEAMALYMPLVDG------VVIQ 59 ++ G+ A+A I G RF + YPITPAS E + + + P+ VV+Q Sbjct: 231 WLDGNTAVAIGKIYGGVRFQSYYPITPASDESVYIEAHQDVLMEDPITGDKKKGTIVVVQ 290 Query: 60 MEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTG 119 EDE+A+I IGA+ G +A TATSGPGFSLM E +G+A M E P+V+ RGGPSTG Sbjct: 291 AEDELAAINMAIGAALTGVRAATATSGPGFSLMVEGLGWAGMNEVPVVITYYIRGGPSTG 350 Query: 120 QPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV 179 PT +Q D++ I+ HG+ IVL+ EAF I A NLAEKY+TPVI L + + Sbjct: 351 LPTRTAQSDLIFPIFAGHGEFPKIVLASGDHAEAFKDAIWALNLAEKYQTPVIHLVEKTL 410 Query: 180 GHMRERVYIP--EPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGL 237 + + E D+++ K+ ++ + + F D + P G+ Y TG Sbjct: 411 ANSYSTIPYEELELDKLKAERGKIVESGDISYKRFKFTE-DGISPRAFLGKA-TMYYTGD 468 Query: 238 THDERGRPRTVEREVHERVIRRIVEKIERNKK-DIFDYEARELDDAEV--------AIVT 288 H+E G + E V+ R + +R KK ++ D E E ++ I+T Sbjct: 469 EHNEEG-------HISEDVVNRTMMYEKRMKKLEVADKEIPEESRVKIYGDLNSRNLIIT 521 Query: 289 TGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYH 348 G LR I L E LL+I PF L+ K+ ++I E N Sbjct: 522 WG-SPTGVLRDI--LEESNFDFTLLQIRMFSPFPKNLVSKLMEGRDKIITVEGNYLAQTS 578 Query: 349 LVREGANGKAEVKLISKIGG 368 L+ + GK I K G Sbjct: 579 LLVKMYTGKDVTNSILKWNG 598 >pir||G69170 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621610|gb|AAB85042.1| (AE000836) 2-oxoacid:ferredoxin oxidoreductase, alpha subunit [Methanobacterium thermoautotrophicum] Length = 512 Score = 142 bits (354), Expect = 7e-33 Identities = 107/344 (31%), Positives = 175/344 (50%), Gaps = 19/344 (5%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72 + G EA+ I GCRF + YP+TP++ + ++ D V Q EDEIA+I +G Sbjct: 151 LNGTEAVGIGCIAGGCRFMSSYPMTPSTPLQVFISENAAEFDMVFEQAEDEIAAINMCLG 210 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 AS+AGA+++ ATSG GF+LM+E +G A M ETP+V+ QR GP+ G PT +Q D+ + Sbjct: 211 ASYAGARSLVATSGSGFALMEEAVGLAGMIETPVVIYIGQRPGPAVGLPTRTAQEDLNLA 270 Query: 133 IWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVY-IPEP 191 ++ G+ +L+P +++A + AFNLA++Y+ PV LLSD ++ + Y +P P Sbjct: 271 LYAGPGEFPRAILAPGKLEDAPEIAAHAFNLADRYQIPVFLLSDQ---YLADLYYDLPSP 327 Query: 192 DEIEIVNRKLPQN-EEEAKLPFGDPHGDFVPPMPIFGRGYRTY-VTGLTHDERGRPRTVE 249 E + + + E + F D + P I G G T V HDE G T + Sbjct: 328 QIGEEPSYHITRTWEGYRRFEF---TADGISPRGIPGYGSGTVRVDSDEHDEEGL-ITED 383 Query: 250 REVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKE-LRELGI 308 +V R++ + ++E K D E D A++ G S ++E + G Sbjct: 384 LDVRRRMVEKRNLRLEMLKDDTLKPEV--YGDNSSALICWG----STYWLVREAIESSGA 437 Query: 309 KAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL-GQLYHLVR 351 ++ + ++P + +E + +R V E N GQ L++ Sbjct: 438 DVSMVHFSQVYPLPHDTLE-LLESFDRTAVVENNYRGQFADLLK 480 >gi|11498355 2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA) [Archaeoglobus fulgidus] >gi|7433693|pir||E69343 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain orA - Archaeoglobus fulgidus >gi|2649863|gb|AAB90491.1| (AE001053) 2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA) [Archaeoglobus fulgidus] Length = 532 Score = 131 bits (326), Expect = 1e-29 Identities = 120/389 (30%), Positives = 180/389 (45%), Gaps = 52/389 (13%) Query: 9 KADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIA 68 K + + G AIA + AG +FY YP+TPAS I +A V +Q E+EIA+I Sbjct: 178 KKELVSGARAIAEGMLAAGLKFYYAYPMTPASPILHILAADSRCV---ALQPENEIAAIM 234 Query: 69 AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128 IG+++ G +A TSG GF+LM E+I A M E P++++ QR GPSTG T +Q D Sbjct: 235 MAIGSAFGGERAAVGTSGGGFALMSESISLAGMAEVPVLIILAQRSGPSTGMATYTAQQD 294 Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188 + ++ HG+ LIV SP T+++++ NLA +++TP ILL++ H+ E + Sbjct: 295 LYFALNPAHGEFPLIVASPITIEDSYRLAGELLNLAWQFQTPAILLTEK---HITESLAT 351 Query: 189 PEPD-----EIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIF---GRGYRTYVTGLTHD 240 + + E+EI K + A G + P IF + Y Sbjct: 352 AKLEGVVKREVEIFREKGELFKRYAITESG--ISPYAAPPAIFKANSNEHDEYGFATDDA 409 Query: 241 ERGRPRTVEREVHERVIRRIVEKIE-----RNKKDIFDYEARELDDAEVAIVTTGIVARS 295 E +R E IRR+V + +N KD IVT G S Sbjct: 410 ETATKMYAKRMRKEEEIRRVVANLNPYVVVKNGKD--------------WIVTWG----S 451 Query: 296 ALRAIKEL-RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVREG 353 A+KE+ ELG ++ + P + KI+G V + E N G L L+ Sbjct: 452 NFGAVKEVAEELGFSVAAIRY--MRPL---FLPKISGNV---FCVECNYTGLLARLIE-- 501 Query: 354 ANGKAEVKLISKIGGEVHTPMEIVDFIRR 382 A G EVK I + G TP E+ + + + Sbjct: 502 AEG-VEVKRILRWDGRPFTPEEVREEVEK 529 >gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA) [Archaeoglobus fulgidus] >gi|7449955|pir||D69506 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain AF2053 [similarity] - Archaeoglobus fulgidus >gi|2648476|gb|AAB89196.1| (AE000961) 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA) [Archaeoglobus fulgidus] Length = 366 Score = 116 bits (287), Expect = 5e-25 Identities = 111/387 (28%), Positives = 164/387 (41%), Gaps = 57/387 (14%) Query: 8 GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIA 65 G + +EAIA A LA A YPITP S I E ++ + +D +++E E + Sbjct: 12 GMKKLLTSNEAIAEAVKLAKPDVIAAYPITPQSPIVEKLSEMVDSGELDSRFVRVESEHS 71 Query: 66 SIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPS 125 ++ +IGA+ AGA+ TATS G + M E +A + PIV+ R S G P Sbjct: 72 AMGVVIGAATAGARVFTATSSHGLAYMYEMCWWAAGSRLPIVMALAAR---SIGAP---- 124 Query: 126 QGDIMQSIWGTHGDH---------SLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSD 176 W HGDH I+ QEAFD T+ AF L+E+ PV + D Sbjct: 125 --------WNIHGDHLDLMAMRDLGWIISVAENAQEAFDMTLNAFMLSEEVNIPVAVAID 176 Query: 177 AEVGHMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTG 236 M + E E+EI P+ + LP D + V FG T Sbjct: 177 GFT--MSHTAEVVEVREVEIP----PRKQAYRILPGMDVALNAV----TFGEARMTARYD 226 Query: 237 LTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSA 296 L D +E+E V E L+DA+ A+V TG ++ Sbjct: 227 LAKDLENSAELIEKEYGGLV------------------ERYRLEDADYAVVVTGGLSGDV 268 Query: 297 LRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHL-VREGAN 355 A+ LRE G+K G+L++ I PF + ++ + +V + V N L V A Sbjct: 269 KDAVDMLREEGVKMGVLRLKFIRPFPKKAVKSLPSQV--LVVDRANTDLRGTLSVEVAAC 326 Query: 356 GKAEVKLISKIGGEVHTPMEIVDFIRR 382 G V +++ IGG T E+ ++R Sbjct: 327 GVENVNVVAGIGGRYPTVEELYSCLKR 353 >dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase alpha subunit [Hydrogenobacter thermophilus] Length = 400 Score = 110 bits (272), Expect = 3e-23 Identities = 106/385 (27%), Positives = 165/385 (42%), Gaps = 51/385 (13%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMA-LYMPLVDGVVIQMEDEIASIAAI 70 F+ G EA+ A A YPITP SE + L++ GV + E E ++ I Sbjct: 32 FMTGSEAVKEAVKRASVDASVSYPITPQSEAAHLIGELWVEGYVGVYFRGESEFGVMSEI 91 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRG--GPSTGQPTLPSQGD 128 G + AGA+ +T TSGPG EN T P+ +V + RG P + QP Sbjct: 92 AGCALAGARTITTTSGPGTLRAMENFPMWAGTRIPVQLVLMARGVNAPLSIQPDNLEVSF 151 Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEK--YRTPVILLSDAE-VGHMRER 185 ++ D ++ T Q+ FD + F +AE+ PVI + D V H RE Sbjct: 152 LL--------DTGCMIWYAETAQDLFDMILAGFVVAEQPDVHVPVITVVDGFFVSHTRET 203 Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGD---PHGDFVPPMPIFGRGYRTYVTGLTHD-- 240 V +P PD+I + P N A +P D P G F+ + Y +Y T + Sbjct: 204 VMLP-PDDIALP----PYNPYRAPMPVIDAEVPPGRFLRDPFVMKSNYISYATHASWQWE 258 Query: 241 -----ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARS 295 ER RP + +R ++E +A++ V G + Sbjct: 259 VRAAIERSRPYA------KHYLRGLIEHFGD-------------PEADLVFVACGTASAQ 299 Query: 296 ALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVREGA 354 A A++ L + GI A ++K+ TI PF E + + + I+VPE N +G L VR Sbjct: 300 AKEAVRMLEDEGISARVVKLKTIRPFPIEELREATKGAKYIFVPEFNVVGWLEREVRRYL 359 Query: 355 NGKAEVKLIS--KIGGEVHTPMEIV 377 G + ++I ++ G + P E++ Sbjct: 360 YGHSSAEIIGAPRVAGGMTMPAEVI 384 >sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7449945|pir||E69099 pyruvate synthase (EC 1.2.7.1) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622870|gb|AAB86209.1| (AE000929) pyruvate oxidoreductase, alpha subunit [Methanobacterium thermoautotrophicum] Length = 383 Score = 106 bits (263), Expect = 4e-22 Identities = 104/384 (27%), Positives = 168/384 (43%), Gaps = 38/384 (9%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV----IQMEDEIASIA 68 I ++A+A AA LA + YPITP + I E +A ++ DG + I++E E ++++ Sbjct: 6 ISANQAVAEAAKLAKPKVIPVYPITPQTSISEYLAKFV--ADGELKAEYIRVESEHSAMS 63 Query: 69 AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128 A +GAS AG + TATS G +LM E + A PIV+ + R + L D Sbjct: 64 ACVGASGAGVRVFTATSSQGLALMHEIVYAAAGLRNPIVMANANRALSA----PLSIWND 119 Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEK---YRTPVILLSDAEVGHMRER 185 SI D + + + QEA D + ++ ++E ++ L + H E Sbjct: 120 QQDSI--AERDSGWMQIYVESGQEALDSVLLSYRVSEDRDVLLPSMVCLDGFILTHTVEP 177 Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPH--GDFVPPMPIFGRGYRTYVTGLTHDERG 243 V IP ++++ LP+ + + L +P G F P Y+ E+ Sbjct: 178 VDIPSQEDVDSF---LPEFQPQVMLDPDEPMSLGTFTDP--------DYYMEARYEVEKA 226 Query: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303 R+ R++ ER R E R + +Y +DAE+ +V G V + I EL Sbjct: 227 MERS--RKIIERACREFSEMFGREYGLVEEYRC---EDAEIILVAMGSVCSTLREVIDEL 281 Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL-----GQLYHLVREGANGKA 358 R+ G GLLK+ PF E I+ ++ V + N+ G LY + + Sbjct: 282 RDKGKAVGLLKVRVHRPFPAEEIKSAVRNASKVAVLDKNITFSVGGALYTEISALLRDRE 341 Query: 359 EVKLISKIGGEVHTPMEIVDFIRR 382 I +GG TP I + +RR Sbjct: 342 VYGFIVGLGGRDITPAHIEEIVRR 365 >pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus >gi|2983644|gb|AAC07211.1| (AE000728) ferredoxin oxidoreductase alpha subunit [Aquifex aeolicus] Length = 404 Score = 106 bits (261), Expect = 6e-22 Identities = 108/386 (27%), Positives = 164/386 (41%), Gaps = 52/386 (13%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMA-LYMPLVDGVVIQMEDEIASIAAI 70 FI G EA+ AA A YPITP SE + L+ GV + E E ++ + Sbjct: 35 FITGSEAVKEAAKRASVDASISYPITPQSEAAHMLGELWREGYIGVYFRGESEFGVMSEV 94 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRG--GPSTGQPTLPSQGD 128 G + AGA+ +T TSGPG E + PI +V + RG P + QP Sbjct: 95 AGCAMAGARTITTTSGPGTMRAMEVFPMWAGSRLPIQLVLMARGINSPLSIQPDNLEISF 154 Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEK--YRTPVILLSDA-EVGHMRER 185 ++ D +V T QE FD I F +AE+ P+I D + H RE Sbjct: 155 LL--------DTGCMVWHAETAQELFDMIIAGFVVAEQPDVHVPIITAIDGFFISHTREA 206 Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGD---PHGDFVPPMPIFGRGYRTYVTGLTHD-- 240 VY+P P++I + P N +A +P D P G F+ + Y +Y T + Sbjct: 207 VYLP-PEDIALP----PYNPYKAPMPPIDMEMPPGRFMRDPFVMKSNYISYATHASWQFE 261 Query: 241 -----ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARS 295 ER RP + +R +VE + EV + +G A Sbjct: 262 VRAAIERSRPYA------KHYLRGLVEHFGD-------------PEGEVLFIASGTAAAQ 302 Query: 296 ALRAIKEL-RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVREG 353 A A + L E GIKA +L++ T+ PF E + + + I++PE N +G L V+ Sbjct: 303 AKEATQILIHEEGIKARVLRLKTLRPFPTEEVREAVKGAKYIFIPEFNVVGWLEREVKRA 362 Query: 354 ANGKAEVKLIS--KIGGEVHTPMEIV 377 G ++ + ++GG + P E + Sbjct: 363 LYGYTDIPIFGTPRVGGGMTMPPEFI 388 >gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-2) [Sulfolobus solfataricus] Length = 400 Score = 104 bits (258), Expect = 1e-21 Identities = 92/326 (28%), Positives = 149/326 (45%), Gaps = 46/326 (14%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70 I G+EA+A LA YPITP + I E +A ++ ++++E E +++AA Sbjct: 6 ISGNEAVALGVKLARVGVTGIYPITPQTTIIEKLAEMRAKGEIETEIVRVESEHSAMAAT 65 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 GA+ G +A TAT+ G M E + + + P+V+V G + G P Sbjct: 66 FGAALGGVRAFTATASQGLLYMHEMVWWVAGSRVPVVMV---VGTRAVGAP--------- 113 Query: 131 QSIWGTHGDHS------LIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GH 181 +IW H D + I+ S QEA D T++AF ++E R P+++ D + H Sbjct: 114 WNIWNEHTDFTSERDSGWIMAFASNPQEALDLTLQAFRISEDERVFLPMMIGMDGFILSH 173 Query: 182 MRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDP--HGDFVPPMPIFGRGYRTYVTGLTH 239 + V IP+ D+++ LP + + DP G+ PP GY + Sbjct: 174 TKTNVLIPDQDQVDDF---LPPRRQPYVIDPEDPVGMGNIFPP-----EGYMRLRESIDL 225 Query: 240 DERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYE----ARELDDAEVAIVTTGIVARS 295 R E VI+ I + + + DY + +L+DA+ A+V G A Sbjct: 226 ALRN---------SEDVIKEIGREYNKKINPLGDYSTLNVSYKLEDADYAVVLMGAWAGD 276 Query: 296 ALRAIKELRELGIKAGLLKINTIWPF 321 A+ A+ LRE GIK G+L+I + P+ Sbjct: 277 AMEAVDTLREKGIKIGMLRIRYLRPW 302 >gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-1) [Sulfolobus solfataricus] Length = 385 Score = 101 bits (249), Expect = 2e-20 Identities = 99/339 (29%), Positives = 153/339 (44%), Gaps = 45/339 (13%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVD--GVVIQMEDEIASIAAIIG 72 G+ A+A A A + A +PITP + + E ++ Y+ + +I++E E +++A+I G Sbjct: 13 GNHAVAYAVKQAKPKVLAVFPITPQTTMLEKLSEYISSEELKAELIKVESEHSALASIYG 72 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A+ AGA+ TATS G M E I +A PIV R + +P S Sbjct: 73 AALAGARVFTATSSQGLLYMTEMIYWAGGQRVPIVAAVATR---AIAEP---------WS 120 Query: 133 IWGTHGDH------SLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMR 183 IW H D I + VQEA+D TI+AF ++E R PV++ D + H Sbjct: 121 IWDDHQDFVSKRDAIWIQIMAENVQEAYDMTIQAFRISEDERVILPVMMGFDGFILTHTM 180 Query: 184 ERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDP--HGDFVPPMPIFGRGYRTYVTGLTHDE 241 ER+ + E +E V+ LP + + F DP G P Y Sbjct: 181 ERIEVLEDNE---VDNFLPPRQFNL-IDFSDPIAIGPIATPEEYIKYRYEAM-------- 228 Query: 242 RGRPRTVEREVHERVIRRIVEKIER--NKKDIFDYEARELDDAEVAIVTTGIVARSALRA 299 + +ER + VI I+ + ER +K E + +DA+ VT G + A Sbjct: 229 ----KAMERA--KGVIEEIMGEYERISGRKQHGLVECYKCEDAKYVFVTMGAWSGDGKAA 282 Query: 300 IKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYV 338 + LR+ G+K GLLKI PF E +E+ ++ + V Sbjct: 283 VDRLRDSGVKTGLLKIRVFRPFPKEKVEEYLRSMKGVVV 321 >pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain PAB1472 [similarity] - Pyrococcus abyssi (strain Orsay) >gi|5458784|emb|CAB50271.1| (AJ248287) KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (EC 1.-.-.-) (VOR) [Pyrococcus abyssi] Length = 395 Score = 101 bits (249), Expect = 2e-20 Identities = 100/336 (29%), Positives = 152/336 (44%), Gaps = 27/336 (8%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV--IQMEDEIASIAAI 70 + G+ A A A + A + A YPITP + I E +A ++ + + I +E E +++AA Sbjct: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 70 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 IGAS GA+ TATS G +LM E + +A PIV+VDV R P D Sbjct: 71 IGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR----AMAPPWSVWDDQT 126 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188 S+ + D + QE +D + AF +AE P +++ A + H E V I Sbjct: 127 DSL--SQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184 Query: 189 PEPDEIEIVNRKLPQNEEEAKL-PFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRP-R 246 P+ E+V+ LP + L F +P P +R Y H+E + + Sbjct: 185 PQ----ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFR-YKLARAHEEAKKVIK 239 Query: 247 TVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELREL 306 V RE ER R E IE+ +DDA+ + G + + A++ LR+ Sbjct: 240 DVGREFGERFGRDYSEMIEK----------AYIDDADFVFMGMGSLMGTVKEAVELLRKQ 289 Query: 307 GIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342 G K G K+ PF E + +IA V+ I V + N Sbjct: 290 GYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325 >emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin oxidoreductase alpha-2 chain [Thermoplasma acidophilum] Length = 402 Score = 98.3 bits (241), Expect = 1e-19 Identities = 103/374 (27%), Positives = 168/374 (44%), Gaps = 48/374 (12%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAIIG 72 G++A+A A LA +F + YPITP + I E +A + +D +++E E +++AA+ Sbjct: 23 GNDAVAYGAKLARVKFISAYPITPQTTIVEKLASMIANDELDAKYVEVESEHSALAAVFA 82 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 + G ++ TATS G M E + + PIV+ V R + G P + Sbjct: 83 SELTGVRSYTATSSHGLLYMHEMLHWVAGQRLPIVMSVVNR---AIGPPW---------N 130 Query: 133 IWGTHGDHS-------LIVLSPSTVQEAFDFTIRAFNLAEK--YRTPVILLSDAEV-GHM 182 IW D + V S S QEA D I + +AE P++ + DA + H Sbjct: 131 IWADQSDTINQRDTGWMQVYSESN-QEAMDTIIMGYKIAENSGVMLPLMSMEDAFILSHT 189 Query: 183 RERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDP--HGDFVPPMPIFGRGYRTYVTGLTHD 240 E V + + D +VN LP + + ++ +P +G + P F + + + + Sbjct: 190 SEPVTMRDQD---LVNEYLPDLDLKFRIDPENPMGYGSYDTPDGSFMEFKKDMIDSMNN- 245 Query: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300 R+V + ++ E E N + E +DDA+ AI+ G VA +A I Sbjct: 246 --------ARKVIKEETQKFNEMFETNYGALI--ERYRMDDADYAIIAMGTVASTARFVI 295 Query: 301 KELRELGIKAGLLKINTIWPFDF-ELIE-----KIAGKVERIYVPEMNLGQLYHLVREGA 354 LRE G+ GL++I PF + E++E K AG ++R V G Y V G Sbjct: 296 DRLRENGLNIGLIRIRYFRPFPYDEILEDLKNVKSAGVIDR-SVSFGLAGVTYSEVISGL 354 Query: 355 NGKAEVKLISKIGG 368 G+ + + S I G Sbjct: 355 YGRINIPVSSFIVG 368 >sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280154|pir||T45085 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain vorA - Pyrococcus furiosus >gi|1197360|emb|CAA59502.1| (X85250) 2-ketovalerate ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus] Length = 394 Score = 96.7 bits (237), Expect = 4e-19 Identities = 95/335 (28%), Positives = 152/335 (45%), Gaps = 25/335 (7%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV--IQMEDEIASIAAI 70 + G+ A A AA+ A + A YPITP + I E +A ++ + + I +E E +++AA Sbjct: 10 VSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 69 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 IGAS GA+ TATS G +LM E + +A PIV+VDV R P D Sbjct: 70 IGASATGARTFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR----AMAPPWSVWDDQT 125 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188 S+ + D + QE +D + A+ +AE P +++ A + H + V I Sbjct: 126 DSL--SQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNVPAMVVESAFILSHTYDVVEMI 183 Query: 189 PEPDEIEIVNRKLPQNEEEAKLP-FGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRT 247 P+ E+V+ LP + L F +P P +R Y H+E Sbjct: 184 PQ----ELVDEFLPPRKPLYSLANFDEPIAVGALATPNDYYEFR-YKLAKAHEE------ 232 Query: 248 VEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELG 307 ++V + V + E+ R+ + E +DDA+ + G + + A+ LR+ G Sbjct: 233 -AKKVIKEVGKEFGERFGRDYSQMI--ETGYIDDADFVFMGMGSLMGTVKEAVDLLRKEG 289 Query: 308 IKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342 K G K+ PF E + +IA V+ I V + N Sbjct: 290 YKVGYAKVRWFRPFPKEELVEIAESVKGIAVLDRN 324 >pir||A71114 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3257088|dbj|BAA29771.1| (AP000003) 397aa long hypothetical ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 397 Score = 94.8 bits (232), Expect = 2e-18 Identities = 96/336 (28%), Positives = 153/336 (44%), Gaps = 27/336 (8%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV--IQMEDEIASIAAI 70 + G+ A A AA+ A + A YPITP + I E +A ++ + + I +E E +++AA Sbjct: 13 VSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 72 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 IGAS GA+ TATS G +LM E + +A + PIV+V+V R P D Sbjct: 73 IGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNR----AMAPPWSVWDDQT 128 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188 S+ + D + QE +D + A+ +AE P +++ A + H E V I Sbjct: 129 DSL--SQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFILSHTYEVVNMI 186 Query: 189 PEPDEIEIVNRKLPQNEEEAKL-PFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRP-R 246 P+ E+V+ LP + L F +P P +R Y H+E + + Sbjct: 187 PQ----ELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFR-YKIAKAHEEAKKVIK 241 Query: 247 TVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELREL 306 +V +E ER R + IE ++DA+ + G + + A+ LR+ Sbjct: 242 SVGKEFGERFGRDYSKMIETG----------YIEDADFVFMGMGSLMGTVKEAVDLLRKE 291 Query: 307 GIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342 G K G K+ PF E + +IA V+ I V + N Sbjct: 292 GYKVGYAKVRWFRPFPKEELLEIAESVKGIAVLDRN 327 >sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) Length = 394 Score = 94.8 bits (232), Expect = 2e-18 Identities = 96/336 (28%), Positives = 153/336 (44%), Gaps = 27/336 (8%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV--IQMEDEIASIAAI 70 + G+ A A AA+ A + A YPITP + I E +A ++ + + I +E E +++AA Sbjct: 10 VSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 69 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 IGAS GA+ TATS G +LM E + +A + PIV+V+V R P D Sbjct: 70 IGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNR----AMAPPWSVWDDQT 125 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188 S+ + D + QE +D + A+ +AE P +++ A + H E V I Sbjct: 126 DSL--SQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFILSHTYEVVNMI 183 Query: 189 PEPDEIEIVNRKLPQNEEEAKL-PFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRP-R 246 P+ E+V+ LP + L F +P P +R Y H+E + + Sbjct: 184 PQ----ELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFR-YKIAKAHEEAKKVIK 238 Query: 247 TVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELREL 306 +V +E ER R + IE ++DA+ + G + + A+ LR+ Sbjct: 239 SVGKEFGERFGRDYSKMIETG----------YIEDADFVFMGMGSLMGTVKEAVDLLRKE 288 Query: 307 GIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342 G K G K+ PF E + +IA V+ I V + N Sbjct: 289 GYKVGYAKVRWFRPFPKEELLEIAESVKGIAVLDRN 324 >gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alpha subunit [Methanococcus maripaludis] Length = 387 Score = 94.4 bits (231), Expect = 2e-18 Identities = 103/383 (26%), Positives = 159/383 (40%), Gaps = 42/383 (10%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70 I G A A AA LA A YPITP + E +A ++ ++ I++E E ++++A Sbjct: 7 ITGTSAAAEAAKLADVDVIAAYPITPQTTCVEKLADFVANGELNAEYIKVESEHSAMSAS 66 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 IGAS AGA+A TATS G +LM E + A P+V+++ R + Q + Sbjct: 67 IGASAAGARAFTATSSQGLALMHEVLFAAAGMRVPVVMMNANRALSAPINIWNDQQDSLS 126 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLA--EKYRTPVILLSDAEV-GHMRERVY 187 Q D I L QE D I+AF +A EK PV++ D + H E V Sbjct: 127 QR------DTGWIQLYAEDNQEVLDLVIQAFKIAEDEKVLLPVMVNLDGFILTHTVEPVT 180 Query: 188 IPEPDEI-------EIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240 +P+ + + E + L + + GDP+ Y Sbjct: 181 LPKQENVLDFIGTYEPKHAYLDPKKPMTQGALGDPN-------------YYMETRYAIET 227 Query: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300 + V +VH+ EK R + E+ L+ AE IV G + + I Sbjct: 228 AMENAKKVIADVHD----AFAEKFNRAYGNGL-IESYNLEKAENVIVAMGSICGTIKDMI 282 Query: 301 KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE------MNLGQLYHLVREGA 354 ++ G++ GLLKI P E+I+ + + + + MN G +Y V Sbjct: 283 DLKKKEGVEIGLLKIRCYRPLPIEMIKDALKNAKNVAILDKSISLGMNKGAIYADVASHL 342 Query: 355 NGKAEVKLISKIGGEVHTPMEIV 377 K V I +GG TP +I+ Sbjct: 343 KDKKTVNYIVGLGGRDITPEDIL 365 >emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin oxidoreductase [Thermotoga maritima] >gi|4980501|gb|AAD35111.1|AE001690_5 (AE001690) pyruvate ferredoxin oxidoreductase, alpha subunit [Thermotoga maritima] Length = 394 Score = 93.2 bits (228), Expect = 4e-18 Identities = 103/328 (31%), Positives = 146/328 (44%), Gaps = 36/328 (10%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV----IQMEDEIASIA 68 + G EA+A A A YPITP + I E A ++ DGVV I +E E ++++ Sbjct: 12 VTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFV--ADGVVRTEMIPVESEHSAMS 69 Query: 69 AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQR--GGPSTGQPTLPSQ 126 A++GA+ AGA+AMTATS G +LM E + A PIV+ V R GP Sbjct: 70 AVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPIN---IHCDH 126 Query: 127 GDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLA--EKYRTPVILLSDAEV-GHMR 183 D M D I L T QEA+DFTI A LA E R PV++ D + H Sbjct: 127 SDAM-----AERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGV 181 Query: 184 ERVYIPEPDEIEIVNRKLPQNEEEAKLPFGD-PHGDFVPPMPIFGRGYRTYVTGLTHDER 242 E V PDE+ K E + P D H P+ ++ + E Sbjct: 182 EPVEF-YPDELV----KKFVGELKPMYPLLDTEHPVTWGPLDLYDYYF----------EH 226 Query: 243 GRPRTVEREVHERVIRRIVEKIERN-KKDIFDYEARELDDAEVAIVTTGIVARSALRAIK 301 R + E ++V I ++ E + + E ++DAE +V G + + Sbjct: 227 KRQQIEAMENVKKVFPEIAKEFEETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVD 286 Query: 302 ELRELGIKAGLLKINTIWPFDFELIEKI 329 ELRE G K G LKI PF E ++++ Sbjct: 287 ELREEGYKVGSLKIWMFRPFPKEQLQEL 314 >sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7449946|pir||C72427 pyruvate synthase (EC 1.2.7.1) alpha chain - Thermotoga maritima (strain MSB8) Length = 392 Score = 93.2 bits (228), Expect = 4e-18 Identities = 103/328 (31%), Positives = 146/328 (44%), Gaps = 36/328 (10%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV----IQMEDEIASIA 68 + G EA+A A A YPITP + I E A ++ DGVV I +E E ++++ Sbjct: 10 VTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFV--ADGVVRTEMIPVESEHSAMS 67 Query: 69 AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQR--GGPSTGQPTLPSQ 126 A++GA+ AGA+AMTATS G +LM E + A PIV+ V R GP Sbjct: 68 AVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPIN---IHCDH 124 Query: 127 GDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLA--EKYRTPVILLSDAEV-GHMR 183 D M D I L T QEA+DFTI A LA E R PV++ D + H Sbjct: 125 SDAM-----AERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGV 179 Query: 184 ERVYIPEPDEIEIVNRKLPQNEEEAKLPFGD-PHGDFVPPMPIFGRGYRTYVTGLTHDER 242 E V PDE+ K E + P D H P+ ++ + E Sbjct: 180 EPVEF-YPDELV----KKFVGELKPMYPLLDTEHPVTWGPLDLYDYYF----------EH 224 Query: 243 GRPRTVEREVHERVIRRIVEKIERN-KKDIFDYEARELDDAEVAIVTTGIVARSALRAIK 301 R + E ++V I ++ E + + E ++DAE +V G + + Sbjct: 225 KRQQIEAMENVKKVFPEIAKEFEETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVD 284 Query: 302 ELRELGIKAGLLKINTIWPFDFELIEKI 329 ELRE G K G LKI PF E ++++ Sbjct: 285 ELREEGYKVGSLKIWMFRPFPKEQLQEL 312 >pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit - Pyrococcus horikoshii >gi|3257092|dbj|BAA29775.1| (AP000003) 398aa long hypothetical ferredoxin oxidoreductase alpha-2 subunit [Pyrococcus horikoshii] Length = 398 Score = 93.2 bits (228), Expect = 4e-18 Identities = 97/327 (29%), Positives = 147/327 (44%), Gaps = 24/327 (7%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70 ++ +EA A AA LA + A +PITP++ + E ++ ++ +D I++E E ++I+A+ Sbjct: 10 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAV 69 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 +GAS AG + TAT+ G +LM E + A PIV+ G S P + D Sbjct: 70 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMA---IGNRSLSAP-INIWNDWQ 125 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRERVY 187 SI + D I QEA D + A+ +AE R P ++ DA + H E V Sbjct: 126 DSI--SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 183 Query: 188 IPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRT 247 IP+ E+V+ L E E K + DP F Y L D + R Sbjct: 184 IPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYME-AKYLVWDAMEKARK 237 Query: 248 VEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELG 307 V E +R K ++ E + DDAE+ VT G +A + + + RE G Sbjct: 238 VIDEAFAEFEKRFGRKYQK-------IEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEG 290 Query: 308 IKAGLLKINTIWPFDFELIEKIAGKVE 334 K G K+ PF E I +A K + Sbjct: 291 YKVGAAKMTVYRPFPVEEIRALAKKAK 317 >sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) Length = 395 Score = 93.2 bits (228), Expect = 4e-18 Identities = 97/327 (29%), Positives = 147/327 (44%), Gaps = 24/327 (7%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70 ++ +EA A AA LA + A +PITP++ + E ++ ++ +D I++E E ++I+A+ Sbjct: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAV 66 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 +GAS AG + TAT+ G +LM E + A PIV+ G S P + D Sbjct: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMA---IGNRSLSAP-INIWNDWQ 122 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRERVY 187 SI + D I QEA D + A+ +AE R P ++ DA + H E V Sbjct: 123 DSI--SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Query: 188 IPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRT 247 IP+ E+V+ L E E K + DP F Y L D + R Sbjct: 181 IPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYME-AKYLVWDAMEKARK 234 Query: 248 VEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELG 307 V E +R K ++ E + DDAE+ VT G +A + + + RE G Sbjct: 235 VIDEAFAEFEKRFGRKYQK-------IEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEG 287 Query: 308 IKAGLLKINTIWPFDFELIEKIAGKVE 334 K G K+ PF E I +A K + Sbjct: 288 YKVGAAKMTVYRPFPVEEIRALAKKAK 314 >pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicobacter pylori (strain 26695) >gi|2314261|gb|AAD08154.1| (AE000617) pyruvate ferredoxin oxidoreductase, alpha subunit [Helicobacter pylori 26695] Length = 407 Score = 92.4 bits (226), Expect = 8e-18 Identities = 92/331 (27%), Positives = 149/331 (44%), Gaps = 56/331 (16%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAIIG 72 G+ A + A A A YPITP++ I + + VDG + +E E A+++A +G Sbjct: 15 GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVG 74 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A+ AG + TATS G +LM E + A PIV+ V R + + Sbjct: 75 AAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRA---------------LAA 119 Query: 133 IWGTHGDHSLIVLSPST---------VQEAFDFTIRAFNLAE--KYRTPVILLSDAEV-G 180 HGDHS + LS + QEA+DFT+ AF +AE K R P I+ D + Sbjct: 120 PLNIHGDHSDMYLSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCS 179 Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240 H + V P + + + + + + L DF P+ Y H Sbjct: 180 HTVQNV---RPLSDAVAYQFVGEYQTKHSLL------DFDKPV-----SYGAQAEEEWHY 225 Query: 241 ERGRPRTVEREVHERVI--RRIVEKIERNKKDIFDYEAR-----ELDDAEVAIVTTGIVA 293 E + ++H ++ ++E++ + + + +L+DAE+AI G Sbjct: 226 EH------KAQLHHAIMSASSVIEEVFNDFAKLTGRQYHLTKTFQLEDAEIAIFALGTTY 279 Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFE 324 SA+ A KE+R+ GIKAG+ I+++ PF +E Sbjct: 280 ESAIVAAKEMRKKGIKAGVATIHSLRPFPYE 310 >pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter pylori (strain J99) >gi|4155626|gb|AAD06616.1| (AE001531) Pyruvate ferrodoxin oxidoreductase [Helicobacter pylori J99] Length = 407 Score = 92.4 bits (226), Expect = 8e-18 Identities = 92/331 (27%), Positives = 149/331 (44%), Gaps = 56/331 (16%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAIIG 72 G+ A + A A A YPITP++ I + + VDG + +E E A+++A +G Sbjct: 15 GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVG 74 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A+ AG + TATS G +LM E + A PIV+ V R + + Sbjct: 75 AAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRA---------------LAA 119 Query: 133 IWGTHGDHSLIVLSPST---------VQEAFDFTIRAFNLAE--KYRTPVILLSDAEV-G 180 HGDHS + LS + QEA+DFT+ AF +AE K R P I+ D + Sbjct: 120 PLNIHGDHSDMYLSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCS 179 Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240 H + V P + + + + + + L DF P+ Y H Sbjct: 180 HTVQNV---RPLSDAVAYQFVGEYQTKHSLL------DFDKPV-----SYGAQAEEEWHY 225 Query: 241 ERGRPRTVEREVHERVI--RRIVEKIERNKKDIFDYEAR-----ELDDAEVAIVTTGIVA 293 E + ++H ++ ++E++ + + + +L+DAE+AI G Sbjct: 226 EH------KAQLHHAIMSASSVIEEVFNDFAKLTGRQYHLTKTFQLEDAEIAIFALGTTY 279 Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFE 324 SA+ A KE+R+ GIKAG+ I+++ PF +E Sbjct: 280 ESAIVAAKEMRKKGIKAGVATIHSLRPFPYE 310 >gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alpha subunit [Helicobacter pylori] Length = 396 Score = 92.1 bits (225), Expect = 1e-17 Identities = 91/331 (27%), Positives = 149/331 (44%), Gaps = 56/331 (16%) Query: 15 GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAIIG 72 G+ A + A A A YPITP++ I + + +DG + +E E A+++A +G Sbjct: 15 GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGEFVLVESEHAAMSACVG 74 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A+ AG + TATS G +LM E + A PIV+ V R + + Sbjct: 75 AAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRA---------------LAA 119 Query: 133 IWGTHGDHSLIVLSPST---------VQEAFDFTIRAFNLAE--KYRTPVILLSDAEV-G 180 HGDHS + LS + QEA+DFT+ AF +AE K R P I+ D + Sbjct: 120 PLNIHGDHSDMYLSRDSGWISLCTCNPQEAYDFTLMAFKIAEHQKVRVPTIVNQDGFLCS 179 Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240 H + V P + + + + + + L DF P+ Y H Sbjct: 180 HTVQNV---RPLSDAVAYQFVGEYQTKHSLL------DFDKPV-----SYGAQAEEEWHY 225 Query: 241 ERGRPRTVEREVHERVI--RRIVEKIERNKKDIFDYEAR-----ELDDAEVAIVTTGIVA 293 E + ++H ++ ++E++ + + + +L+DAE+AI G Sbjct: 226 EH------KAQLHHAIMSASSVIEEVFNDFAKLTGRQYHLTKTFQLEDAEIAIFALGTTY 279 Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFE 324 SA+ A KE+R+ GIKAG+ I+++ PF +E Sbjct: 280 ESAIVAAKEMRKKGIKAGVATIHSLRPFPYE 310 >pir||E75038 indolepyruvate ferredoxin oxidoreductase, chain alpha (iora-1) PAB0855 - Pyrococcus abyssi (strain Orsay) >gi|5458715|emb|CAB50202.1| (AJ248287) indolepyruvate ferredoxin oxidoreductase, subunit alpha (iorA-1) [Pyrococcus abyssi] Length = 648 Score = 92.1 bits (225), Expect = 1e-17 Identities = 91/336 (27%), Positives = 143/336 (42%), Gaps = 45/336 (13%) Query: 8 GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASI 67 G+ + G++AI R A+ YA YP TP+SEI + MA + +E + Sbjct: 14 GERVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAAVASRAGVYMEYSTNEKVAF 73 Query: 68 AAIIGASWAGAKAMTATSGPGFSLMQEN---IGYAVMTETPIVVVDVQRGGPSTGQPTLP 124 + ASWAG +AMTA G ++ ++ + Y + +VVV P++ Sbjct: 74 ETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGVNGGLVVVV--------ADDPSMW 125 Query: 125 SQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRE 184 S + Q ++ VL PS+VQEA D AF ++EKY VIL + HMR Sbjct: 126 SSQN-EQDTRAIAKFANIPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRG 184 Query: 185 RVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGR 244 V + E LPQ +E K FGD F + YV Sbjct: 185 DVVLGE----------LPQEIKEGKRKFGD-----------FKKNPERYVD--------- 214 Query: 245 PRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELR 304 +R H+ ++ I + E F++ +DA+V I+ G+ A+ L Sbjct: 215 IPAFQRPKHKWLLETIEKFREEFNNSPFNW-IEGPEDAKVGIIAPGLSYAYVKEALAWLG 273 Query: 305 ELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340 +K +LK+ T +P + L+EK +ER+ + E Sbjct: 274 VDNVK--VLKLGTPFPVPYGLLEKFFQGLERVLIVE 307 >sp|O58495|IORA_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7450338|pir||F71124 probable indolepyruvate ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3257173|dbj|BAA29856.1| (AP000003) 648aa long hypothetical indolepyruvate ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 648 Score = 91.3 bits (223), Expect = 2e-17 Identities = 94/338 (27%), Positives = 146/338 (42%), Gaps = 49/338 (14%) Query: 8 GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASI 67 G+ + G++AI R A+ YA YP TP+SEI + MA+ + +E + Sbjct: 14 GEKVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAMVAKKAGVYMEYSTNEKVAF 73 Query: 68 AAIIGASWAGAKAMTATSGPGFSLMQEN---IGYAVMTETPIVVVDVQRGGPSTGQPTLP 124 + ASWAG +AMTA G ++ ++ + Y + IVVV P++ Sbjct: 74 ETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGINGGLIVVV--------ADDPSMW 125 Query: 125 SQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRE 184 S + Q ++ VL PS+VQEA D AF ++EKY VIL + HMR Sbjct: 126 SSQN-EQDTRAIAKFANIPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRG 184 Query: 185 RVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGR 244 V + E LPQ +E K FG+ F + YV Sbjct: 185 DVVLGE----------LPQEIKEGKRKFGN-----------FKKNPEKYVD--------- 214 Query: 245 PRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKE-L 303 +R H ++ I + E F++ +DA+V I+ G+ + +KE L Sbjct: 215 IPAFQRPKHPWLLETIEKFREEFNTSPFNW-IEGPEDAKVGIIAPGL----SYAYVKEAL 269 Query: 304 RELGI-KAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340 LGI +LK+ T +P + L+EK +ER+ + E Sbjct: 270 AWLGIDNVKILKLGTPFPVPYGLLEKFFNGLERVLIVE 307 >gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (porA) [Archaeoglobus fulgidus] >gi|7449947|pir||D69462 pyruvate synthase (EC 1.2.7.1) alpha chain - Archaeoglobus fulgidus >gi|2648853|gb|AAB89548.1| (AE000986) pyruvate ferredoxin oxidoreductase, subunit alpha (porA) [Archaeoglobus fulgidus] Length = 391 Score = 90.1 bits (220), Expect = 4e-17 Identities = 103/381 (27%), Positives = 156/381 (40%), Gaps = 51/381 (13%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP---LVDGVVIQMEDEIASIAA 69 ++G ++A + L YPITP +EI E +A L D I E E + + Sbjct: 5 VRGFYSVAYSVKLCKPNVICAYPITPQTEIVENLAAMYANGELGDAEYITAESEFGAASM 64 Query: 70 IIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDI 129 ++GAS AGA+ TAT G LM E + A PIV+V+ R + P Sbjct: 65 LVGASAAGARVFTATCSQGLILMSEVLFNAAGMRLPIVLVNTNR---ALSAPL------- 114 Query: 130 MQSIWGTHGDH------SLIVLSPSTVQEAFDFTIRAFNLAE--KYRTPVILLSDAEVGH 181 SIW H D ++ + QEA D +A+ +AE K P ++ D G+ Sbjct: 115 --SIWNDHQDSMAMRDAGIMQVYVENNQEAHDMIPQAYKVAENRKVLLPFMICMD---GY 169 Query: 182 MRERVYIP-EPDEIEIVNRKLPQNEEEAKLPFGDP--HGDFVPPMPIFGRGYRTYVTGLT 238 Y P + E E V+ LP E A + P G + PP Y + + Sbjct: 170 KLTHAYEPVDLLEQETVDSFLPPYEPAAYMTTKKPLAFGCYAPP-----HVYMEFRVAM- 223 Query: 239 HDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALR 298 R R + +V + E E +D + + D+++ +V G V + Sbjct: 224 QQAMERARKIMLDVFK-------EWGELTGRDWGGHITVDFPDSKIFVVAMGSVVGLLRK 276 Query: 299 AIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKA 358 ++ELR G+ GL+KI T PF E + + E++ V L V G G Sbjct: 277 VVEELRGEGLSVGLIKIRTFRPFPVEELREALKDAEKVIV-------LDRSVSFGYEGPV 329 Query: 359 EVKLISKIGGEVHTPMEIVDF 379 ++L S I G H+ EI F Sbjct: 330 SIELKSAIYG--HSSAEIYSF 348 >pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 - Pyrococcus abyssi (strain Orsay) >gi|5458781|emb|CAB50268.1| (AJ248287) PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1) (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) [Pyrococcus abyssi] Length = 395 Score = 89.3 bits (218), Expect = 7e-17 Identities = 94/331 (28%), Positives = 148/331 (44%), Gaps = 32/331 (9%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70 ++ +EA A AA LA + A +PITP++ + E ++ ++ +D I++E E ++I+A+ Sbjct: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 +GAS AG + TAT+ G +LM E + A PIV+ + G L + +I Sbjct: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM--------AIGNRALSAPINIW 118 Query: 131 QSIWGT--HGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRER 185 T D I QEA D + A+ +AE R P ++ DA + H E Sbjct: 119 NDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEP 178 Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGY--RTYVTGLTHDERG 243 V IP+ E+V+ L E E K + DP F Y Y+ + Sbjct: 179 VEIPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMEN-- 231 Query: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303 R+V + +K R + I +Y DDAE+ VT G +A + + + Sbjct: 232 -----ARKVIDEAFAEFEKKFGRKYQKIEEYRT---DDAEIIFVTMGSLAGTLKDWVDKK 283 Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVE 334 RE G K G K+ PF E I ++A K + Sbjct: 284 REEGYKVGAAKMTVYRPFPVEEIRELAKKTK 314 >sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280155|pir||T45088 pyruvate synthase (EC 1.2.7.1) alpha-2 chain [imported] - Pyrococcus furiosus >gi|1197363|emb|CAA59505.1| (X85250) pyruvate ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus] Length = 396 Score = 87.4 bits (213), Expect = 3e-16 Identities = 96/339 (28%), Positives = 153/339 (44%), Gaps = 30/339 (8%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70 ++ +EA A AA LA + A +PITP++ I E ++ ++ +D I++E E ++I+A Sbjct: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEHSAISAC 66 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 +GA+ AG + TAT+ G +LM E + A PIV+ + G L + +I Sbjct: 67 VGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVM--------AIGNRALSAPINIW 118 Query: 131 QSIWGT--HGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRER 185 T D + QEA D + A+ +AE R P ++ DA + H E Sbjct: 119 NDWQDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEP 178 Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGY-RTYVTGLTHDERGR 244 V IP+ E+V+ L E E K + DP F Y + T ER Sbjct: 179 VEIPDQ---EVVDEFL--GEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERA- 232 Query: 245 PRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELR 304 ++V + +K R + I +Y+ +DA++ VT G +A + I + R Sbjct: 233 -----KKVIDEAFAEFEKKFGRKYQKIEEYKT---EDADIIFVTMGSLAGTLNEWIDKKR 284 Query: 305 ELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL 343 E G K G KI PF E I ++A K + + E N+ Sbjct: 285 EEGYKVGAAKITVYRPFPVEEIRELAKKAKVLAFLEKNI 323 >pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus >gi|2983615|gb|AAC07184.1| (AE000726) ferredoxin oxidoreductase alpha subunit [Aquifex aeolicus] Length = 389 Score = 85.8 bits (209), Expect = 8e-16 Identities = 100/390 (25%), Positives = 152/390 (38%), Gaps = 64/390 (16%) Query: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMA-LYMPLVDGVVIQMEDEIASIAAI 70 FI G +A A A A YPITP SE + LY + E+E +++AI Sbjct: 22 FITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRAEEEYGAMSAI 81 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQR--GGPSTGQPTLPSQGD 128 GA GA+A TATSGPG E I P V+ + R P + QP Sbjct: 82 AGAVRGGARAFTATSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISY 141 Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEK---YRTPVILLSDAEVGHMRER 185 ++ S L+VL Q+ FDFT+ F ++EK Y V+ V H + Sbjct: 142 LLNS--------GLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193 Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPP-------------MPIFGRGYRT 232 V +P E+ KLP DP+ VPP P+ + + Sbjct: 194 VELP---------------PEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMS 238 Query: 233 YVTGLTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELD----DAEVAIVT 288 Y+ +H + + R K I Y ++ DAEV +V Sbjct: 239 YL-----------------IHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVA 281 Query: 289 TGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL-GQLY 347 +G A A + G+ GL+K+ ++ PF + I + + + VPE N+ G L Sbjct: 282 SGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLA 341 Query: 348 HLVREGANGKAEVKLISKIGGEVHTPMEIV 377 V+ V ++ G + P+E++ Sbjct: 342 KEVKAAIPNSGIVVDGPRVYGGMTLPVELI 371 >gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-like) [Sulfolobus solfataricus] Length = 415 Score = 83.1 bits (202), Expect = 5e-15 Identities = 96/398 (24%), Positives = 149/398 (37%), Gaps = 49/398 (12%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAI 70 + G +A+A AA+ A A YPI P +E+ + ++ + +D I E E + Sbjct: 14 MNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFETV 73 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 AS AGA+ + +SG G+ E I P+V + R G + +M Sbjct: 74 KHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDALM 133 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE 190 D +++ T QEAFD + A+ +AE R + L + G + I Sbjct: 134 VR------DVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVR 187 Query: 191 PDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVER 250 E+V LP P+ P PI T + D R Sbjct: 188 LPPRELVKNFLP--------PYNRGKYLVHPDNPI------TVAPQVNEDWVMEIRRQHE 233 Query: 251 EVHERVIRRIVEKIERNKKDIFDY---------------EARELDDAEVAIVTTGIVARS 295 E ER IVE E KK Y E +DDAEV ++ G V++ Sbjct: 234 EAMERARSVIVEAYEEFKKVFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKP 293 Query: 296 ALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL--------GQLY 347 AIK +R G K G+L+I PF + + + + V + + G +Y Sbjct: 294 MKVAIKNMRRQGYKVGMLRIRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIY 353 Query: 348 HLVREGANGKAE----VKLISKIGGEVHTPMEIVDFIR 381 H VR + + I +GG T ++ I+ Sbjct: 354 HEVRSSLYDLDQRPRVMNFIGGLGGREITIQDVEKIIK 391 >pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolobus solfataricus >gi|1707735|emb|CAA69455.1| (Y08256) pyruvate-ferredoxin oxidoreductase alpha-2 [Sulfolobus solfataricus] Length = 415 Score = 83.1 bits (202), Expect = 5e-15 Identities = 96/398 (24%), Positives = 149/398 (37%), Gaps = 49/398 (12%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAI 70 + G +A+A AA+ A A YPI P +E+ + ++ + +D I E E + Sbjct: 14 MNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFETV 73 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 AS AGA+ + +SG G+ E I P+V + R G + +M Sbjct: 74 KHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDALM 133 Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE 190 D +++ T QEAFD + A+ +AE R + L + G + I Sbjct: 134 VR------DVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVR 187 Query: 191 PDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVER 250 E+V LP P+ P PI T + D R Sbjct: 188 LPPRELVKNFLP--------PYNRGKYLVHPDNPI------TVAPQVNEDWVMEIRRQHE 233 Query: 251 EVHERVIRRIVEKIERNKKDIFDY---------------EARELDDAEVAIVTTGIVARS 295 E ER IVE E KK Y E +DDAEV ++ G V++ Sbjct: 234 EAMERARSVIVEAYEEFKKVFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKP 293 Query: 296 ALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL--------GQLY 347 AIK +R G K G+L+I PF + + + + V + + G +Y Sbjct: 294 MKVAIKNMRRQGYKVGMLRIRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIY 353 Query: 348 HLVREGANGKAE----VKLISKIGGEVHTPMEIVDFIR 381 H VR + + I +GG T ++ I+ Sbjct: 354 HEVRSSLYDLDQRPRVMNFIGGLGGREITIQDVEKIIK 391 >gb|AAK42250.1| Indolepyruvate ferredoxin oxidoreductase alpha subunit (iorA) [Sulfolobus solfataricus] Length = 612 Score = 81.1 bits (197), Expect = 2e-14 Identities = 88/328 (26%), Positives = 134/328 (40%), Gaps = 52/328 (15%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72 I G+EAIA A+ AG AGYP TP++EI E + + + +E + G Sbjct: 11 ILGNEAIAFGALSAGVSVAAGYPGTPSTEIIETLMKFGKIY---AEWSTNEKVAFETAYG 67 Query: 73 ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132 A+ GA A+T G ++ + + + T +V V PS SQ + Sbjct: 68 AAINGAFALTTMKHVGLNVAADPLISSSYTGVEGALVIVSADDPSMWS----SQNEQDNR 123 Query: 133 IWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPD 192 +G H + V+ P Q A D TI AF L+ K + PVI S +GH+R V + P Sbjct: 124 YYGLHA--LIPVVEPYDPQSAHDLTIEAFKLSNKVKHPVIFRSTTRIGHIRGPVELKPPS 181 Query: 193 EIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREV 252 P M + + YV + R R ++R Sbjct: 182 R---------------------------PVMGKVIKNPKRYVLVPENARRDRVEQLKR-- 212 Query: 253 HERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAGL 312 RI E++E ++ D +D+E I+ +GI + AIKEL IKA + Sbjct: 213 ----WERIEEEVE-GLNELID------NDSENLIIASGISFGYVIDAIKELE---IKANI 258 Query: 313 LKINTIWPFDFELIEKIAGKVERIYVPE 340 L++ T P LI K +R+ + E Sbjct: 259 LRLTTPVPIPKRLILKAVSNSKRVLIVE 286 >gb|AAD28766.1| (AF132216) 2-oxoisovalerate oxidoreductase beta subunit [Prevotella albensis] Length = 104 Score = 80.8 bits (196), Expect = 3e-14 Identities = 43/88 (48%), Positives = 56/88 (62%), Gaps = 2/88 (2%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAI 70 ++G+EAIA AAI G + GYPITP SEI E +AL P VV+Q E E+ASI + Sbjct: 8 MKGNEAIAHAAIRCGADGFFGYPITPQSEIIETLALLKPWETTGMVVLQAESEVASINML 67 Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGY 98 G + AG + +T +S PG +LMQE I Y Sbjct: 68 YGGAGAGKRVLTTSSSPGVALMQEGIAY 95 >emb|CAC12141.1| (AL445066) indolepyruvate ferredoxin oxidoreductase, alpha subunit related protein [Thermoplasma acidophilum] Length = 605 Score = 80.4 bits (195), Expect = 3e-14 Identities = 88/343 (25%), Positives = 139/343 (39%), Gaps = 69/343 (20%) Query: 9 KADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIA 68 KA F+ G+EAIA AA+ AG AGYP TP++EI E + + P D V +E + Sbjct: 4 KAKFMIGNEAIAAAAVHAGVSVAAGYPGTPSTEIIENVRKFGP--DVYVEWSVNEKIAFE 61 Query: 69 AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128 GA+ +G + A G ++ + + + T TG + S D Sbjct: 62 TAYGAAMSGGTGLVAVKHVGLNVASDPMFSSSYTGI-------------TGSLVIVSADD 108 Query: 129 IMQSIWGT--------HGDHSLI-VLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV 179 S+W + +G H+LI VL P VQ A+D T++AF ++ + PVIL + + Sbjct: 109 --SSMWSSQNEQDNRFYGLHALIPVLEPYDVQSAYDLTLKAFEVSRLFHHPVILRTTTRI 166 Query: 180 GHMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTH 239 GH+R V + E P + K P TYV + Sbjct: 167 GHVRSNVIYEDHHE--------PLRGKVIKDP-------------------NTYVLAPEN 199 Query: 240 DERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRA 299 R + +ER +I + YE D +I+ TG ++ S L+ Sbjct: 200 ARSDRKKQLER----------WREISDYLSSLCSYE----PDGGDSIIITGGISYSYLK- 244 Query: 300 IKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342 + L + GI +L+++ P I + R+ V E N Sbjct: 245 -EALEDAGIHTNVLRLDATVPIPESAILNHINGIRRVLVVEEN 286 >gi|11499084 indolepyruvate ferredoxin oxidoreductase, subunit alpha (iorA) [Archaeoglobus fulgidus] >gi|6685558|sp|O28783|IORA_ARCFU INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7450334|pir||H69435 indolepyruvate ferredoxin oxidoreductase, subunit alpha (iorA) homolog - Archaeoglobus fulgidus >gi|2649079|gb|AAB89760.1| (AE001000) indolepyruvate ferredoxin oxidoreductase, subunit alpha (iorA) [Archaeoglobus fulgidus] Length = 623 Score = 79.6 bits (193), Expect = 6e-14 Identities = 91/347 (26%), Positives = 153/347 (43%), Gaps = 69/347 (19%) Query: 8 GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV-IQME---DE 63 G+ F+ G+EAIAR AI AG +A YP TP+SEI + ++ L+ G + ME +E Sbjct: 11 GEKVFLLGNEAIARGAIEAGIDVFAAYPGTPSSEIADTLSDACRLLRGKMDFYMEYSANE 70 Query: 64 IASIAAIIGASWAGAKAMTATSGPGFSLMQENI-GYAVMTETPIVVVDVQRGG---PSTG 119 + +GAS AG +AM G ++ + + +A + RGG + Sbjct: 71 KVAFEVAVGASLAGKRAMATMKHVGVNVAADPLFSFAYVG---------ARGGFVLVTAD 121 Query: 120 QPTLPSQGDIMQSIWGTHGDHS-LIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAE 178 P++ S + + W +G + L V+ PS+VQEA D+ F+L+EK+ P+IL S Sbjct: 122 DPSMHSSQNEQDNRW--YGKAAKLPVVEPSSVQEAKDYAKLCFDLSEKFGLPMILRSYTR 179 Query: 179 VGHMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLT 238 + H V + K+P+ E P D V P Sbjct: 180 LSHASGVVEL----------GKIPEKEFSRVEWERHPETDVVLP---------------A 214 Query: 239 HDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELD-----DAEVAIVTTGIVA 293 H + +P +E+ +EKIER + + E++ D +V I+ G+ Sbjct: 215 HARKLKPILLEK----------LEKIERY------FNSSEMNWVDEGDGDVGIIACGL-- 256 Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340 S + L L + +LK++++ P LIE +++++ V E Sbjct: 257 -SYAYTKEALENLNLNLPVLKLSSMHPLPERLIENFVSQMKKVIVVE 302 >gb|AAD17273.1| (AF119361) ferredoxin oxidoreductase a-subunit [Frankia sp. EuIK1] Length = 671 Score = 73.4 bits (177), Expect = 4e-12 Identities = 54/172 (31%), Positives = 80/172 (46%), Gaps = 13/172 (7%) Query: 30 FYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIAS------IAAIIGASWAGAKAMTA 83 F YPITPA+++ ++ L V S AA A WA A Sbjct: 258 FLGAYPITPATDVLHELS---KLTSHDVRHSRPRTRSRRSARRSAARSPACWASPSTSGA 314 Query: 84 TSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIWGTHGDHSLI 143 G + + + +V+VQRGGPSTG PT Q D++Q+++G HG+ L Sbjct: 315 RHG---AQVPRRSACDLAGSCRWFIVNVQRGGPSTGLPTKTEQSDLLQALYGRHGEAPLP 371 Query: 144 VLSPSTVQEAFDFTIRAFNL-AEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194 VL+ + + FD A + A RTPVILLSD+ + + E +P +E+ Sbjct: 372 VLAGESPADCFDAAFEAAQMRAGGRRTPVILLSDSYIANGSEPWKVPSVEEL 423 >pir||G75085 indolepyruvate ferredoxin oxidoreductase, chain alpha (iora-2) PAB0718 - Pyrococcus abyssi (strain Orsay) >gi|5458500|emb|CAB49988.1| (AJ248286) indolepyruvate ferredoxin oxidoreductase, subunit alpha (iorA-2) [Pyrococcus abyssi] Length = 613 Score = 71.0 bits (171), Expect = 2e-11 Identities = 84/334 (25%), Positives = 138/334 (41%), Gaps = 60/334 (17%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72 + G+EAIA A+ +G F GYP TP++E+ E +A P V +E ++ G Sbjct: 5 LMGNEAIAYGALESGIAFATGYPGTPSTEVIETIARLKPEV--FAEWAPNEKVALEEAAG 62 Query: 73 ASWAGAKAMTATSGPGFSLMQE---NIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDI 129 S+AG +++ G ++ + ++ Y+ + E +V++ GP T Q Q D Sbjct: 63 VSYAGLRSLVTMKCVGLNVAADPLMSLAYSGV-EGGLVILVADDPGPHTSQ---TEQDD- 117 Query: 130 MQSIWGTHGDHSLI-VLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188 +G +++ VL P QEA D A+ L+EKY+ PVI + V H V + Sbjct: 118 -----RYYGKIAILPVLEPYDPQEAHDLIKYAYELSEKYKVPVIFRTTTRVNHTTADVEV 172 Query: 189 PEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTV 248 E E+ NRK P+F + YV R R + + Sbjct: 173 GEFVEL---NRK-----------------------PVFKKDIERYVRASMEGNRRRHKWL 206 Query: 249 EREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSA-LRAIKE-LREL 306 IR+I E+ + + E + GI+ A +KE L + Sbjct: 207 -----NETIRKIEEEFNSMPFNWVEGEGK-----------LGIIVEGAPYNYVKEILPSI 250 Query: 307 GIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340 G +LK++T P +L+ VE++ V E Sbjct: 251 GEDFKILKLSTPHPLPRKLVLDFLKSVEKVIVIE 284 >pir||D71055 probable indolepyruvate ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3257555|dbj|BAA30238.1| (AP000005) 618aa long hypothetical indolepyruvate ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 618 Score = 71.0 bits (171), Expect = 2e-11 Identities = 57/182 (31%), Positives = 88/182 (48%), Gaps = 16/182 (8%) Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72 + G+EAIA A+ AG F GYP TP++E+ E +A P V +E ++ G Sbjct: 10 LMGNEAIAYGALEAGVSFATGYPGTPSTEVIETIARLKPEV--FAEWAPNEKVALEEAAG 67 Query: 73 ASWAGAKAMTATSGPGFSLMQE---NIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDI 129 AS+AG +++ G ++ + ++ Y+ + E +VV+ GP T Q Q D Sbjct: 68 ASYAGIRSLVTMKCVGLNVAADPLMSLAYSGV-EGGLVVLVADDPGPHTSQ---TEQDD- 122 Query: 130 MQSIWGTHGDHSLI-VLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188 +G SL+ VL P QEA D A+ L+EKY+ P+I + V H V + Sbjct: 123 -----RYYGKISLLPVLEPYDPQEAHDLIKYAYELSEKYKVPIIFRTTTRVNHTTADVEV 177 Query: 189 PE 190 E Sbjct: 178 GE 179 >sp|O07835|IORA_PYRKO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|2209070|dbj|BAA20528.1| (D86221) indolepyruvate ferredoxin oxidoreductase alpha subunit [Pyrococcus sp.] Length = 647 Score = 70.6 bits (170), Expect = 3e-11 Identities = 83/343 (24%), Positives = 145/343 (42%), Gaps = 59/343 (17%) Query: 8 GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASI 67 G+ + G+ AI R A+ A +A YP TP+SE+ + +E + Sbjct: 14 GERVLLLGNHAIERGALEANIAVFAAYPGTPSSELTIRWQTVAKKAGVYMEYSTNEKVAF 73 Query: 68 AAIIGASWAGAKAMTATSGPGFSLMQEN----IGYAVMTETPIVVVDVQRGGPSTGQPTL 123 + A+W+G +AMTA G ++ ++ +G V I+V D P++ Sbjct: 74 ETALAAAWSGLRAMTAMKHVGLNVAADSFLSSVGMGVEGGFVIMVAD---------DPSM 124 Query: 124 -PSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHM 182 SQ + ++ + + VL PS+ EA + T AF L+EK++ VIL + H Sbjct: 125 WSSQNEQDTRVYAKFAN--VPVLEPSSPHEAKEMTKYAFELSEKFKHFVILRTTTRSSHA 182 Query: 183 RERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDER 242 R V + E LP+ + K FG F + +V H + Sbjct: 183 RGDVVLGE----------LPEEIKTGKRKFGK-----------FKKDPTRFVDVPAHARK 221 Query: 243 GRPRTVEREVHERVIRRIVEKIERNKKDI----FDY-EARELDDAEVAIVTTGIVARSAL 297 P I+EKIE+ ++++ F++ E +E DA+V I+ G+ Sbjct: 222 FHP-------------LILEKIEKIREELNNCPFNWIEGKE--DAKVGIIAPGLSYAYVK 266 Query: 298 RAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340 A+ L +K +LK+ T +P + L+ K +E++ + E Sbjct: 267 EALAWLGVEDVK--ILKLGTPFPVPYGLLGKFFDGLEKVLIVE 307 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.140 0.407 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 146513081 Number of Sequences: 2977 Number of extensions: 6453748 Number of successful extensions: 15647 Number of sequences better than 1.0e-10: 68 Number of HSP's better than 0.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 15471 Number of HSP's gapped (non-prelim): 82 length of query: 385 length of database: 189,106,746 effective HSP length: 55 effective length of query: 330 effective length of database: 156,189,961 effective search space: 51542687130 effective search space used: 51542687130 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 166 (69.1 bits)