BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0346 (korA-2) DE:2-ketoglutarate ferredoxin oxidoreductase,
subunit alpha (korA-2)
         (385 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp...   774  0.0
pir||F71046 probable ferredoxin oxidoreductase alpha subunit - P...   740  0.0
pir||B71047 probable ferredoxin oxidoreductase alpha subunit - P...   438  e-122
pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp...   437  e-121
sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET...   418  e-116
pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7....   409  e-113
sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET...   409  e-113
pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7....   354  1e-96
pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7....   294  1e-78
gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit a...   278  7e-74
pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...   261  1e-68
pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacte...   258  7e-68
gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:accepto...   256  3e-67
pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (s...   240  3e-62
dbj|BAB06093.1| (AP001515) pyruvate synthase alpha subunit [Baci...   210  3e-53
gb|AAG19013.1| (AE005001) pyruvate ferredoxin oxidoreductase, su...   202  5e-51
pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...   196  3e-49
sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB...   196  3e-49
pir||A72519 probable 2-oxoacid--ferredoxin oxidoreductase alpha ...   186  4e-46
pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha...   184  1e-45
pir||S22396 pyruvate synthase (EC 1.2.7.1) alpha chain [validate...   176  4e-43
gb|AAG19514.1| (AE005043) putative 2-ketoglutarate ferredoxin ox...   176  4e-43
emb|CAB60189.1| (AL132824) putative oxidoreductase alpha-subunit...   175  1e-42
emb|CAC08296.1| (AL392148) putative oxidoreductase [Streptomyces...   175  1e-42
pir||F70864 probable oxidoreductase alpha subunit - Mycobacteriu...   169  5e-41
emb|CAC11404.1| (AL445063) probable pyruvate ferredoxin oxidored...   167  2e-40
emb|CAC11904.1| (AL445065) probable 2-oxoacid ferredoxin oxidore...   167  2e-40
gb|AAK42926.1| 2-oxoacid--ferredoxin oxidoreductase, alpha chain...   164  1e-39
pir||B72288 2-oxoacid ferredoxin oxidoreductase, alpha subunit -...   162  8e-39
emb|CAA75641.1| (Y15464) ferredoxin oxidoreductase-like (gamma a...   152  5e-36
pir||JC4919 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...   152  5e-36
pir||G69170 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...   142  7e-33
gi|11498355 2-oxoacid ferredoxin oxidoreductase, subunit alpha (...   131  1e-29
gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit...   116  5e-25
dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase al...   110  3e-23
sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...   106  4e-22
pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex ae...   106  6e-22
gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin...   104  1e-21
gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin...   101  2e-20
pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase...   101  2e-20
emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin ox...    98  1e-19
sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA...    97  4e-19
pir||A71114 probable ferredoxin oxidoreductase alpha subunit - P...    95  2e-18
sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA...    95  2e-18
gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alph...    94  2e-18
emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin ox...    93  4e-18
sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...    93  4e-18
pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit -...    93  4e-18
sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...    93  4e-18
pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicob...    92  8e-18
pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter py...    92  8e-18
gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alp...    92  1e-17
pir||E75038 indolepyruvate ferredoxin oxidoreductase, chain alph...    92  1e-17
sp|O58495|IORA_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA ...    91  2e-17
gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (p...    90  4e-17
pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 -...    89  7e-17
sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...    87  3e-16
pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex ae...    86  8e-16
gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin...    83  5e-15
pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolo...    83  5e-15
gb|AAK42250.1| Indolepyruvate ferredoxin oxidoreductase alpha su...    81  2e-14
gb|AAD28766.1| (AF132216) 2-oxoisovalerate oxidoreductase beta s...    81  3e-14
emb|CAC12141.1| (AL445066) indolepyruvate ferredoxin oxidoreduct...    80  3e-14
gi|11499084 indolepyruvate ferredoxin oxidoreductase, subunit al...    80  6e-14
gb|AAD17273.1| (AF119361) ferredoxin oxidoreductase a-subunit [F...    73  4e-12
pir||G75085 indolepyruvate ferredoxin oxidoreductase, chain alph...    71  2e-11
pir||D71055 probable indolepyruvate ferredoxin oxidoreductase al...    71  2e-11
sp|O07835|IORA_PYRKO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA ...    71  3e-11

>pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha  (kora-2)
           PAB0346 - Pyrococcus abyssi (strain Orsay)
           >gi|5457939|emb|CAB49429.1| (AJ248284) 2-ketoglutarate
           ferredoxin oxidoreductase, subunit alpha (korA-2)
           [Pyrococcus abyssi]
           Length = 385
           
 Score =  774 bits (1977), Expect = 0.0
 Identities = 385/385 (100%), Positives = 385/385 (100%)

Query: 1   MRFPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQM 60
           MRFPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQM
Sbjct: 1   MRFPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQM 60

Query: 61  EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120
           EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ
Sbjct: 61  EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120

Query: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180
           PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG
Sbjct: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180

Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240
           HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD
Sbjct: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240

Query: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300
           ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI
Sbjct: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300

Query: 301 KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV 360
           KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV
Sbjct: 301 KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV 360

Query: 361 KLISKIGGEVHTPMEIVDFIRRDFS 385
           KLISKIGGEVHTPMEIVDFIRRDFS
Sbjct: 361 KLISKIGGEVHTPMEIVDFIRRDFS 385


>pir||F71046 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3258091|dbj|BAA30774.1| (AP000006) 385aa
           long hypothetical ferredoxin oxidoreductase alpha
           subunit [Pyrococcus horikoshii]
           Length = 385
           
 Score =  740 bits (1890), Expect = 0.0
 Identities = 363/385 (94%), Positives = 376/385 (97%)

Query: 1   MRFPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQM 60
           MR PFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL+DGVVIQM
Sbjct: 1   MRLPFPVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLIDGVVIQM 60

Query: 61  EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120
           EDEI SIAA+IGASWAG KAMTATSGPGFSLMQENIGYAVMTETPIVVV+VQRGGPSTGQ
Sbjct: 61  EDEIGSIAAVIGASWAGVKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRGGPSTGQ 120

Query: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180
           PTLPSQGDIMQSIWGTHGDH+LIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG
Sbjct: 121 PTLPSQGDIMQSIWGTHGDHTLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180

Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240
           HMRERVYIPEPDEIEIVNRKLP +EEEAKLPFGDPHGD VPPMPIFG+GYRTYVTGLTHD
Sbjct: 181 HMRERVYIPEPDEIEIVNRKLPGSEEEAKLPFGDPHGDGVPPMPIFGKGYRTYVTGLTHD 240

Query: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300
           E+GRPRTVEREVHER+IRRI EKIE+NKKDIFDYEARELDDAE+AIVTTGIVARSALRAI
Sbjct: 241 EKGRPRTVEREVHERLIRRIFEKIEKNKKDIFDYEARELDDAEIAIVTTGIVARSALRAI 300

Query: 301 KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV 360
           KELR LGIKAGLLKINTIWPFDFELIEK+A KVERIYVPEMNLGQLYHLV+EGANGKAEV
Sbjct: 301 KELRNLGIKAGLLKINTIWPFDFELIEKVAEKVERIYVPEMNLGQLYHLVKEGANGKAEV 360

Query: 361 KLISKIGGEVHTPMEIVDFIRRDFS 385
           KLISKIGGEVHTPMEI+DFIRRD S
Sbjct: 361 KLISKIGGEVHTPMEIIDFIRRDLS 385


>pir||B71047 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3258095|dbj|BAA30778.1| (AP000006) 408aa
           long hypothetical ferredoxin oxidoreductase alpha
           subunit [Pyrococcus horikoshii]
           Length = 408
           
 Score =  438 bits (1114), Expect = e-122
 Identities = 224/370 (60%), Positives = 271/370 (72%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71
           F+ GDEAIA  AI AGCRFYAGYPITP+SEI E MA  +P V G  +QMEDEI SIAA+I
Sbjct: 36  FMMGDEAIAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIGSIAAMI 95

Query: 72  GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131
           GASW G KAMTATSGPGFSLMQENIGYAVMTETPIVVV+VQR GPSTGQ T  +QGD  Q
Sbjct: 96  GASWTGLKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRSGPSTGQATKGAQGDFFQ 155

Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191
           + WGTHGDH +I +SP +V++AF  TIRAFN+AEK RTPVI+L D  +GH RE++ IP+P
Sbjct: 156 ARWGTHGDHPMIAVSPISVEDAFWETIRAFNIAEKLRTPVIVLFDGILGHTREQIRIPDP 215

Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251
           DE+EI  RKLP +EEEAKLPFGDPHGD VPPMP+FG GY T+VTG TH E G      +E
Sbjct: 216 DEVEITYRKLPGSEEEAKLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275

Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311
           VH++++RRI  KIE+N+     YE    DDAE+ +V+ G+ AR +L A+ + RE GIKAG
Sbjct: 276 VHDKLVRRIHRKIEQNRDVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKAREEGIKAG 335

Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371
           L    T+ PF  E + ++  KV  I VPEMNLGQ+   V+   N    +K ++KIGG   
Sbjct: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMVLEVQRFVNDDVILKGVNKIGGVPL 395

Query: 372 TPMEIVDFIR 381
           T  EI+  IR
Sbjct: 396 TVEEILKEIR 405


>pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha  (kora-1)
           PAB2359 - Pyrococcus abyssi (strain Orsay)
           >gi|5457936|emb|CAB49426.1| (AJ248284) 2-ketoglutarate
           ferredoxin oxidoreductase, subunit alpha (korA-1)
           [Pyrococcus abyssi]
           Length = 408
           
 Score =  437 bits (1111), Expect = e-121
 Identities = 217/370 (58%), Positives = 273/370 (73%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71
           F+ GDEA+A  AI AGCRFYAGYPITP+SEI E MA  +P V G  +QMEDEIASIAA++
Sbjct: 36  FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGYYLQMEDEIASIAAMV 95

Query: 72  GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131
           GASW G K MTATSGPGFSLMQEN+GYAVMTETP+V+VDVQR GPSTGQ T  +QGD  Q
Sbjct: 96  GASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFFQ 155

Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191
           + WGTHGDH ++ +SP +V++AF  TIRAFN+AE+ RTPV++L D  +GH RE++ IP+P
Sbjct: 156 ARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDGILGHTREQIRIPDP 215

Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251
           DE+EIV RKLPQNEEEA+LPFGDPHGD VPPMP+FG GY T+VTG TH E G      +E
Sbjct: 216 DEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDVYTQE 275

Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311
           VH++++RRI  KIE+N++    YE    DDAE+ +V+ G+ AR +L A+ + R+ GIK G
Sbjct: 276 VHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKEGIKVG 335

Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371
           L    T+ PF  E + ++  KV  I VPEMNLGQ+   V+   N    +K ++KIGG   
Sbjct: 336 LFVPKTVHPFPGERMRELGKKVRAILVPEMNLGQMILEVQRFVNDDVLLKGVNKIGGVPL 395

Query: 372 TPMEIVDFIR 381
           T  EI+  IR
Sbjct: 396 TVEEILREIR 405


>sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
           OXIDOREDUCTASE ALPHA CHAIN) (KOR)
           (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           >gi|2127893|pir||E64334 2-oxoacid--ferredoxin
           oxidoreductase (EC 1.2.7.-) alpha chain - Methanococcus
           jannaschii >gi|1592279|gb|AAB98264.1| (U67483)
           2-ketoglutarate ferredoxin oxidoreductase, subunit alpha
           (korA) [Methanococcus jannaschii]
           Length = 366
           
 Score =  418 bits (1063), Expect = e-116
 Identities = 208/368 (56%), Positives = 271/368 (73%), Gaps = 9/368 (2%)

Query: 9   KADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIA 68
           K +F+QG++A A+ AI AGCRF+AGYPITP++EI EAMA  +P V G  IQMEDEI SIA
Sbjct: 2   KVEFMQGNQACAKGAIKAGCRFFAGYPITPSTEIAEAMARELPKVGGYYIQMEDEIGSIA 61

Query: 69  AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128
           A+IGASW G KAMTATSGPGFSLMQENIG+A MTETP VVVD+QRGGPSTGQPT+ SQGD
Sbjct: 62  AVIGASWGGLKAMTATSGPGFSLMQENIGFAYMTETPCVVVDIQRGGPSTGQPTMASQGD 121

Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188
           +MQ  WG+HGD+ +I L+PS+VQE +DFTI AFN AEKYR PV +++D  VGHMRE+V +
Sbjct: 122 MMQCRWGSHGDYEVIALAPSSVQEMYDFTIMAFNYAEKYRIPVFVMADEIVGHMREKVIL 181

Query: 189 PEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTV 248
              D IEI+NRK P+ E+  K P+  P    +P MP+FG GY  ++TGLTHDERG P  V
Sbjct: 182 --HDNIEIINRKKPE-EKPCKKPY--PFDKLIPEMPVFGEGYNVHITGLTHDERGYP-DV 235

Query: 249 EREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGI 308
             E H++++RRIV KI +NK +I  +E   L DAE+  V  G  +R+   A++ LRE G+
Sbjct: 236 SPETHDKLVRRIVNKIRKNKDEIIKWEGENL-DAEIVFVCYGSPSRTVKHAVRNLREKGL 294

Query: 309 KAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGG 368
             G +++ T++PF  +L++K+  K +++ VPEMNLGQ+Y+ V        EV L+ KIGG
Sbjct: 295 DVGYIRLITVYPFPDDLLKKL--KAKKVVVPEMNLGQIYYEVERVCKKAEEVILVDKIGG 352

Query: 369 EVHTPMEI 376
           E+H P E+
Sbjct: 353 ELHRPEEL 360


>pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
           - Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2622136|gb|AAB85529.1| (AE000875) 2-oxoglutarate
           oxidoreductase, alpha subunit  [Methanobacterium
           thermoautotrophicum]
           Length = 378
           
 Score =  409 bits (1040), Expect = e-113
 Identities = 202/369 (54%), Positives = 266/369 (71%), Gaps = 3/369 (0%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71
           FIQG++A AR AI AGCRF+AGYPITP++EI E MAL +P   GV +QMEDEI ++ A+I
Sbjct: 8   FIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGVFVQMEDEIGALGAVI 67

Query: 72  GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131
           GA W+G + MTATSGPGFSLMQE++GYA MTETP+V+V+VQRG PSTGQPT+ SQ D+MQ
Sbjct: 68  GAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMMQ 127

Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191
           + WG+HGD+ +I LSPS+VQE FDFT+RAFNLAE+YR PV+++ D  VGHMRE++ I  P
Sbjct: 128 ARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDEIVGHMREKITI--P 185

Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251
           D ++I  R+ P    E  LPF  P  D VP MP FG GYR  VTGLTHDE G P     E
Sbjct: 186 DRVKIRKRRGPSVPPEEFLPFSAPE-DGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNPE 244

Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311
            H R+++R+ +KI R++  I D +    +DA + +++ G  +RS   A+K  RE G++AG
Sbjct: 245 GHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVRAG 304

Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371
            LKINT WPF    +   A +  ++ V EMNLGQ+++ V+  A G AEV+L+ KIGGE+H
Sbjct: 305 YLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFYEVQRVAAGMAEVELLPKIGGEIH 364

Query: 372 TPMEIVDFI 380
            P EI++ I
Sbjct: 365 RPEEILNMI 373


>sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
           OXIDOREDUCTASE ALPHA CHAIN) (KOR)
           (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           Length = 376
           
 Score =  409 bits (1040), Expect = e-113
 Identities = 202/369 (54%), Positives = 266/369 (71%), Gaps = 3/369 (0%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71
           FIQG++A AR AI AGCRF+AGYPITP++EI E MAL +P   GV +QMEDEI ++ A+I
Sbjct: 6   FIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGVFVQMEDEIGALGAVI 65

Query: 72  GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131
           GA W+G + MTATSGPGFSLMQE++GYA MTETP+V+V+VQRG PSTGQPT+ SQ D+MQ
Sbjct: 66  GAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMMQ 125

Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191
           + WG+HGD+ +I LSPS+VQE FDFT+RAFNLAE+YR PV+++ D  VGHMRE++ I  P
Sbjct: 126 ARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDEIVGHMREKITI--P 183

Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251
           D ++I  R+ P    E  LPF  P  D VP MP FG GYR  VTGLTHDE G P     E
Sbjct: 184 DRVKIRKRRGPSVPPEEFLPFSAPE-DGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNPE 242

Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311
            H R+++R+ +KI R++  I D +    +DA + +++ G  +RS   A+K  RE G++AG
Sbjct: 243 GHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVRAG 302

Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371
            LKINT WPF    +   A +  ++ V EMNLGQ+++ V+  A G AEV+L+ KIGGE+H
Sbjct: 303 YLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFYEVQRVAAGMAEVELLPKIGGEIH 362

Query: 372 TPMEIVDFI 380
            P EI++ I
Sbjct: 363 RPEEILNMI 371


>pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
           TM0878 [similarity] - Thermotoga maritima (strain MSB8)
           >gi|4981412|gb|AAD35959.1|AE001753_15 (AE001753)
           pyruvate:ferredoxin 2-oxidoreductase-related protein
           [Thermotoga maritima]
           Length = 386
           
 Score =  354 bits (898), Expect = 1e-96
 Identities = 191/373 (51%), Positives = 251/373 (67%), Gaps = 5/373 (1%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAII 71
           F+QG+EA A  AI AGCRF+AGYPITP++EI E MA  +P V GV +QMEDEIAS AA++
Sbjct: 8   FLQGNEACALGAIKAGCRFFAGYPITPSTEIAEVMARELPKVGGVFVQMEDEIASAAAVV 67

Query: 72  GASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQ 131
           GAS AG K+MTATSGPGFSL+QE IGYA+MTETP V  +V R GPSTG PT P+QGDIMQ
Sbjct: 68  GASLAGVKSMTATSGPGFSLIQEVIGYAIMTETPCVFANVMRLGPSTGLPTKPAQGDIMQ 127

Query: 132 SIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191
           + WGTHGDH++I L PS+V E + + I AFNLAE+YRTPV+ L DA +GHMRE  Y P+ 
Sbjct: 128 TRWGTHGDHAIIALYPSSVAEVYRYIITAFNLAEEYRTPVVFLMDAMLGHMRESFYPPKD 187

Query: 192 DEIEIVNRKLPQN--EEEAKLPFGDPHGDFVPPMPIFGRG-YRTYVTGLTHDERGRPRTV 248
           +E+ I+ R    +  EE+  +PF +       P P+   G  + +V+GL HDE G P + 
Sbjct: 188 EELFIIERLKDTSFGEEDLFVPFSESEYAEPTPFPMAEMGKTKFHVSGLVHDESGFPLS- 246

Query: 249 EREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGI 308
             +  E++IRR+  KI  +  +I  YE  E +DAE+ +V  GIVARSA++A+K  R   I
Sbjct: 247 SPDAAEKLIRRLTNKIRLHADEIAFYEEYETEDAEILVVAYGIVARSAMKAVKIARRDRI 306

Query: 309 KAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEV-KLISKIG 367
           K GL K  TIWP       K+A KV  I + EMNLGQ    +    + +++V + I+K+ 
Sbjct: 307 KVGLFKPITIWPAPVSRFRKLAEKVNTIVIAEMNLGQYAKELISSIDRRSKVIRTINKVN 366

Query: 368 GEVHTPMEIVDFI 380
           GE+  P EI+D I
Sbjct: 367 GELIKPEEILDVI 379


>pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
           Cj0536 [similarity] - Campylobacter jejuni (strain NCTC
           11168) >gi|6968004|emb|CAB75172.1| (AL139075) OORA
           subunit of 2-oxoglutarate:acceptor oxidoreductase
           [Campylobacter jejuni]
           Length = 374
           
 Score =  294 bits (745), Expect = 1e-78
 Identities = 157/369 (42%), Positives = 233/369 (62%), Gaps = 3/369 (0%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIGAS 74
           G+  IA+AAI  GC+F+ GYPITP+SEI   ++  +P  DG  IQMEDEI+ I+  IGA+
Sbjct: 8   GNVLIAKAAIDCGCKFFGGYPITPSSEIAHELSHMLPANDGTFIQMEDEISGISVAIGAA 67

Query: 75  WAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIW 134
            +G K+MTA+SGPG SL  E IG A + E P+V+V+V RGGPSTG PT  +QGD+ Q+  
Sbjct: 68  MSGVKSMTASSGPGISLKAEQIGLAFIAEIPLVIVNVMRGGPSTGLPTRVAQGDLFQAKA 127

Query: 135 GTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194
            THGD + I ++P++++EA+  TIRAFNLAEKY TPV LL D  VGHM  +  +P+  +I
Sbjct: 128 PTHGDFASIAIAPASLEEAYTETIRAFNLAEKYMTPVFLLMDETVGHMNGKAVLPDLKDI 187

Query: 195 EIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREVHE 254
           ++ NRK  + +++   P+     +     P F  GYR +VTGL H + G P T +  + +
Sbjct: 188 KVYNRKKFEGDKKDYKPYAAGENEPATLNPFF-TGYRYHVTGLHHGDIGFP-TEDGVIVK 245

Query: 255 RVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAGLLK 314
           + + R++ KI+ N++DI  YE   LDDAE  I+  G V+RSA  AI+ LRE GIK GL +
Sbjct: 246 KNMERLIGKIKNNQEDICTYEEYMLDDAEFLIIAYGSVSRSAKEAIQRLREQGIKVGLFR 305

Query: 315 INTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVHTPM 374
             T++P   + I ++  K +++ V E+N+GQ    + E    + +   + +  G   TP 
Sbjct: 306 PITLYPVAEKKIAEVVSKFKKVMVSELNMGQYLEEI-ERVTSRRDFISLHRANGRPITPS 364

Query: 375 EIVDFIRRD 383
           EI+  ++ +
Sbjct: 365 EIIAKVKEN 373


>gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA)
           [Archaeoglobus fulgidus]
           >gi|6685587|sp|O29781|KORA_ARCFU 2-OXOGLUTARATE SYNTHASE
           SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA
           CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE
           ALPHA SUBUNIT) >gi|7433685|pir||E69308
           2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-)
           alpha chain korA - Archaeoglobus fulgidus
           >gi|2650159|gb|AAB90768.1| (AE001072) 2-ketoglutarate
           ferredoxin oxidoreductase, subunit alpha (korA)
           [Archaeoglobus fulgidus]
           Length = 346
           
 Score =  278 bits (704), Expect = 7e-74
 Identities = 153/336 (45%), Positives = 209/336 (61%), Gaps = 28/336 (8%)

Query: 11  DFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAI 70
           + IQG+EA  R AI AGC F+AGYPITP+SEI   MA  +P   GV IQMEDEIASI+A+
Sbjct: 4   ELIQGNEAAVRGAINAGCNFFAGYPITPSSEIAHGMAELLPKFGGVFIQMEDEIASISAV 63

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           IGAS AGA AMTATSGPGFSLMQE +GYA +TE+P+V+ +V R GPSTG PT PSQGD M
Sbjct: 64  IGASMAGAVAMTATSGPGFSLMQEGMGYAAITESPVVIFNVMRAGPSTGIPTAPSQGDAM 123

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE 190
           Q+ +G+HGD+ ++VL+P++V++ +  T+ AF +A ++ TPVI+LSD  VGHMRE V +P 
Sbjct: 124 QARYGSHGDYPIVVLAPASVKDMYYLTVEAFKIAFRFSTPVIVLSDEIVGHMRESVALPP 183

Query: 191 PDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVER 250
             EIE   ++     +                      G R + TGL H E G P T + 
Sbjct: 184 LGEIESYEKRAKNLID----------------------GRRRHRTGLVHTENGLP-TTDL 220

Query: 251 EVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKA 310
           E +E+++R +  K      D F    R   +  V  V  G   R A  + K L E G+ A
Sbjct: 221 EEYEKLLRLLFAKF-----DDFRPMVRFEGEEGVLFVAYGSSYRLAKSSAKLLAEKGVSA 275

Query: 311 GLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQL 346
           G+LK+ +++PF  + + + + K + + VPEMN GQ+
Sbjct: 276 GILKLESLFPFPEDAVRRYSKKADLVVVPEMNAGQV 311


>pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
           Helicobacter pylori (strain 26695)
           >gi|2313707|gb|AAD07654.1| (AE000572) ferredoxin
           oxidoreductase, alpha subunit [Helicobacter pylori
           26695]
           Length = 375
           
 Score =  261 bits (660), Expect = 1e-68
 Identities = 145/366 (39%), Positives = 217/366 (58%), Gaps = 7/366 (1%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIGAS 74
           G+E +A+AAI  GCRF+ GYPITP+S+I  AM++ +P   G  IQMEDEI+ I+  +GAS
Sbjct: 8   GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPKCGGHFIQMEDEISGISVSLGAS 67

Query: 75  WAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIW 134
            +G K+MTA+SGPG SL  E IGY+ M E P+V+ DV R GPSTG PT  +QGD+     
Sbjct: 68  MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVAQGDVNFLRH 127

Query: 135 GTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194
             HGD   + L+P+ ++EA+  T+RAFNLAE   TPV LL D  VGHM  +V IP+ +E+
Sbjct: 128 PIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187

Query: 195 E--IVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREV 252
           +   +NRK    +++   P+G    +     P F +GYR +V+GL H   G P T + ++
Sbjct: 188 QKMTINRKEFLGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGFP-TEDAKI 245

Query: 253 HERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL-RELGIKAG 311
              +I R+  KIE  +  I + E  +L+ AE+ ++  G V+ +   A+K+  +E   K G
Sbjct: 246 GGDLIDRLFNKIESKQDIINENEEMDLEGAEIVVIAYGSVSLAVKEALKDYHKESKQKVG 305

Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371
             +  T+WP   + +++I  K E+I V E+N GQ    +      K  V  + +  G   
Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLEEIERAMQRK--VHFLGQANGRTI 363

Query: 372 TPMEIV 377
           +P +I+
Sbjct: 364 SPKQII 369


>pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacter pylori
           (strain J99) >gi|4155084|gb|AAD06119.1| (AE001486)
           SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCTASE [Helicobacter
           pylori J99]
           Length = 375
           
 Score =  258 bits (653), Expect = 7e-68
 Identities = 145/366 (39%), Positives = 215/366 (58%), Gaps = 7/366 (1%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIGAS 74
           G+E +A+AAI  GCRF+ GYPITP+S+I  AM++ +P   G  IQMEDEI+ I+  +GAS
Sbjct: 8   GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPKCGGHFIQMEDEISGISVSLGAS 67

Query: 75  WAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIW 134
            +G K+MTA+SGPG SL  E IGY+ M E P+V+ DV R GPSTG PT  +QGD+     
Sbjct: 68  MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVAQGDVNFLRH 127

Query: 135 GTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194
             HGD   + L+P+ ++EA+  T+RAFNLAE   TPV LL D  VGHM  +V IP+ +E+
Sbjct: 128 PIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187

Query: 195 E--IVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREV 252
           +   +NRK    +++   P+G    +     P F +GYR +V+GL H   G P T + ++
Sbjct: 188 QKMTINRKEFAGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGFP-TEDAKI 245

Query: 253 HERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL-RELGIKAG 311
              +I R+  KIE  +  I + E  +L+  E+ I+  G V+ +   A+K+  +E   K G
Sbjct: 246 GGDLIDRLFHKIESKQDIINENEEMDLEGTEIVIIAYGSVSLAVKEALKDYNKESKQKVG 305

Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371
             +  T+WP   + +++I  K E+I V E+N GQ    +      K  V    +  G   
Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQYLEEIERVMQRK--VHFFGQANGRTI 363

Query: 372 TPMEIV 377
           +P +I+
Sbjct: 364 SPKQII 369


>gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:acceptor oxidoreductase
           [Helicobacter pylori]
           Length = 371
           
 Score =  256 bits (647), Expect = 3e-67
 Identities = 141/334 (42%), Positives = 205/334 (61%), Gaps = 5/334 (1%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIGAS 74
           G+E +A+AAI  GCRF+ GYPITP+S+I  AM++ +P   G  IQMEDEI+ I+  +GAS
Sbjct: 8   GNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPNCGGHFIQMEDEISGISVSLGAS 67

Query: 75  WAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIW 134
            +G K+MTA+SGPG SL  E IGY+ M E P+V+ DV R GPSTG PT   QGD+     
Sbjct: 68  MSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVDQGDVNFLRH 127

Query: 135 GTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194
             HGD   + L+P++++EA+  T RAFNLAE   TPV LL D  VGHM  +V IP+ +E+
Sbjct: 128 PIHGDFKAVALAPASLEEAYTETARAFNLAEMLMTPVFLLMDETVGHMYGKVQIPDLEEV 187

Query: 195 E--IVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREV 252
           +   +NRK    +++   P+G    +     P F +GYR +V+GL H   G P T + ++
Sbjct: 188 QKTTINRKEFVGDKKDYKPYGVAQDEPAVLNPFF-KGYRYHVSGLHHGPIGFP-TEDAKI 245

Query: 253 HERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL-RELGIKAG 311
              +I R+  KIE  +  I + E  +L+ AE+ I+  G V+ +   A+K+  +E   K G
Sbjct: 246 GGDLIDRLFNKIESKQDIINENEEMDLEGAEIVIIAYGSVSLAVKEALKDYHKESNQKVG 305

Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQ 345
             +  T+WP   + +++I  K E+I V E+N GQ
Sbjct: 306 FFRPKTLWPSPAKRLKEIGDKYEKILVIELNKGQ 339


>pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (strain MSB8)
           >gi|4982338|gb|AAD36824.1|AE001814_6 (AE001814)
           2-oxoisovalerate oxidoreductase, beta subunit, putative
           [Thermotoga maritima]
           Length = 356
           
 Score =  240 bits (605), Expect = 3e-62
 Identities = 148/366 (40%), Positives = 203/366 (55%), Gaps = 29/366 (7%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72
           ++G+EAIA +AI AGCR Y  YPITP SEI E MA  +P V GV +Q E EIA++  + G
Sbjct: 9   MKGNEAIAESAIRAGCRLYFAYPITPQSEIAEYMARRLPEVGGVFLQTESEIATVNMVYG 68

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A+  G + MT+TS PGFSLMQE I Y    E P V VDV RGGP  G    PSQGD  Q+
Sbjct: 69  AACTGKRVMTSTSSPGFSLMQEGISYIAGAELPCVFVDVVRGGPGLGN-IQPSQGDYFQA 127

Query: 133 I-WGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP 191
           +  G HGD+ LIVL+PST+QEA D T  AF+LA++YR PV++L+D  +G M E V +PE 
Sbjct: 128 VKGGGHGDYRLIVLAPSTLQEAVDLTQLAFDLADRYRNPVLILADGMIGQMMEPVELPEM 187

Query: 192 DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVERE 251
            ++      LP + + A                   RG R          R     ++  
Sbjct: 188 RDLST----LPDHSDWAL------------------RGARN-----REPHRIAAFNIDPV 220

Query: 252 VHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAG 311
             E++ +R+ EK    +     +E   +D AE  +V  G + R     +  LRE GI AG
Sbjct: 221 GLEKMNKRLQEKYRLIEASEQRWEEYRVDGAEYLMVGYGTMGRILKSVVDSLREEGIPAG 280

Query: 312 LLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLISKIGGEVH 371
           L +  T+WPF    ++++A KV+ I+V EM+ GQ+   V+    GK  V    ++GG V 
Sbjct: 281 LFRPVTLWPFPKRRLKELAKKVQLIFVVEMSSGQMVEDVQISVEGKVPVHFYGRMGGVVP 340

Query: 372 TPMEIV 377
           TP EI+
Sbjct: 341 TPEEIL 346


>dbj|BAB06093.1| (AP001515) pyruvate synthase alpha subunit [Bacillus halodurans]
           Length = 579
           
 Score =  210 bits (528), Expect = 3e-53
 Identities = 138/380 (36%), Positives = 207/380 (54%), Gaps = 16/380 (4%)

Query: 9   KADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIA 68
           K  F+ G++AI   A+ AG RF A YPITPASEI E +   +P   G VIQ EDEIA+  
Sbjct: 196 KRMFMIGNDAIGMGAVAAGSRFMAAYPITPASEIMEYLIKKLPEFGGAVIQTEDEIAACT 255

Query: 69  AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128
             IGA++AG ++ TA++GPG SLM E IG + MTETP+V+VD QRGGPS G PT   Q D
Sbjct: 256 MAIGANYAGVRSFTASAGPGLSLMAEAIGLSGMTETPLVIVDTQRGGPSIGLPTKQEQSD 315

Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188
           +M  I+ THGD   +V++PSTV+EAF  T+ AFN+AE+Y+ PVIL++D  +   ++ V  
Sbjct: 316 LMAMIYSTHGDIPKVVMAPSTVEEAFYDTVEAFNIAEEYQCPVILVTDLALSLGKQTVEP 375

Query: 189 PEPDEIEIVNRKLPQNEEEAKLPFGDPHGDF------VPPMPIFG-RGYRTYVTGLTHDE 241
            +  ++EI    L   ++  +   G+ +  +      V P  + G +    +VTG+ HD+
Sbjct: 376 LDFSKVEIRRGSLQNEDQLTEQEKGEYYKRYELTETGVSPRVLPGQKNGIHHVTGVEHDQ 435

Query: 242 RGRP---RTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSAL- 297
            G+P    T   E  E+ +R++    ER    +  +   E  D  V  + +    R A+ 
Sbjct: 436 TGKPSESATNRIEQMEKRLRKVEALPERFPTPVHIHAPHEEPDLLVIGINS---TRGAIE 492

Query: 298 RAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVREGANG 356
            AI  L    I+     I  + PF    ++    K +++ V E N   QL  L++   + 
Sbjct: 493 EAIPRLEADSIRVNHAHIRLVHPFPKHELQPYLTKAKKVVVVEHNATAQLASLIKMNCDV 552

Query: 357 KAEVKLISKIGGEVHTPMEI 376
           KA ++ + +  G    P EI
Sbjct: 553 KA-IENVLRYDGNPFLPGEI 571


>gb|AAG19013.1| (AE005001) pyruvate ferredoxin oxidoreductase, subunit alpha; PorA
           [Halobacterium sp. NRC-1]
           Length = 582
           
 Score =  202 bits (509), Expect = 5e-51
 Identities = 123/304 (40%), Positives = 173/304 (56%), Gaps = 16/304 (5%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72
           + GDEAI   AI AGCRFYAGYPITPA+++ E +   +    G V+Q EDE+A+I   +G
Sbjct: 202 LNGDEAIGMGAIAAGCRFYAGYPITPATDVMEYLTGRIEQFGGHVVQAEDELAAINLALG 261

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A+ AGA++MTATSGPG  LM E  G    +ETP+V+ +V R GPSTG PT   QGD+   
Sbjct: 262 AARAGARSMTATSGPGIDLMSETFGLVATSETPLVIANVMRSGPSTGMPTKQEQGDLNMM 321

Query: 133 IWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEP- 191
           + G HG+    V++P++V E F  T+ AFNLAEKY+ PV + +D  +  + ER Y PE  
Sbjct: 322 LKGGHGEIPRFVVAPTSVAECFHKTVEAFNLAEKYQLPVYVTADLSMA-VTERTYPPEEF 380

Query: 192 --DEIEIVNRKLP--------QNEEEAKLPFGDPHGDFVPPMPIFG-RGYRTYVTGLTHD 240
             D +EI   KL         QN+ E   P  D   D + P  + G  G     TGL HD
Sbjct: 381 DMDAVEIERGKLVDEDEISAWQNDTEQFRPHADT-ADGISPRAVPGTEGGVHMSTGLEHD 439

Query: 241 ERGRPRTVEREVHERVIRRIVEKIE-RNKKDIFDYEARELDDAEVAIVTTGIVARSALRA 299
           E GR RT + +V    + +   K++   +++ FDY      DA+  +V+ G    + + A
Sbjct: 440 ELGR-RTEDTDVRVDQVDKRYRKVDTAREREQFDYREFGDSDADNLVVSWGSNEGTIVEA 498

Query: 300 IKEL 303
           ++ L
Sbjct: 499 LEYL 502


>pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621790|gb|AAB85209.1| (AE000849) 2-oxoisovalerate
           oxidoreductase, beta subunit  [Methanobacterium
           thermoautotrophicum]
           Length = 348
           
 Score =  196 bits (494), Expect = 3e-49
 Identities = 136/378 (35%), Positives = 198/378 (51%), Gaps = 48/378 (12%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72
           ++G+ A+   A+ AGC  Y GYPITPASEI    + Y P+V    +Q E E A+I  + G
Sbjct: 2   VKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYG 61

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A+ AG + MTA+SGPG SL QE I +    E P V+VDV R GP  G    P QGD  Q 
Sbjct: 62  AAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGN-IGPEQGDYNQI 120

Query: 133 I-WGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE- 190
           +  G HG++  +VL+PS+VQE  D T+ AF LA+KYR PV++L+DA +G M E +  PE 
Sbjct: 121 VKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPEE 180

Query: 191 -----PDEIEIV--NRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERG 243
                PD    V  NR+  +N                             VT +  D   
Sbjct: 181 AVEHRPDTSWAVCGNRETMKN----------------------------LVTSIFLD--- 209

Query: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303
                E E     ++    +IE N+     YE   +DDAE+ +V  GI +R A  A++  
Sbjct: 210 ---FDELEEFNFYLQEKYARIEENE---VRYEEYLVDDAEIVMVAYGISSRVARSAVETA 263

Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLI 363
           R  GI  GLL+  T++PF  + I ++A    R    EM+ GQ+   +R  A+G  +V+L+
Sbjct: 264 RAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDIRM-ASGCRDVELV 322

Query: 364 SKIGGEVHTPMEIVDFIR 381
           +++GG +    ++++ IR
Sbjct: 323 NRMGGNLIELRDVLEKIR 340


>sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB (VOR) (2-OXOISOVALERATE
           OXIDOREDUCTASE BETA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
           OXIDOREDUCTASE BETA SUBUNIT)
           Length = 352
           
 Score =  196 bits (494), Expect = 3e-49
 Identities = 136/378 (35%), Positives = 198/378 (51%), Gaps = 48/378 (12%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72
           ++G+ A+   A+ AGC  Y GYPITPASEI    + Y P+V    +Q E E A+I  + G
Sbjct: 6   VKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYG 65

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A+ AG + MTA+SGPG SL QE I +    E P V+VDV R GP  G    P QGD  Q 
Sbjct: 66  AAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGN-IGPEQGDYNQI 124

Query: 133 I-WGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE- 190
           +  G HG++  +VL+PS+VQE  D T+ AF LA+KYR PV++L+DA +G M E +  PE 
Sbjct: 125 VKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPEE 184

Query: 191 -----PDEIEIV--NRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERG 243
                PD    V  NR+  +N                             VT +  D   
Sbjct: 185 AVEHRPDTSWAVCGNRETMKN----------------------------LVTSIFLD--- 213

Query: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303
                E E     ++    +IE N+     YE   +DDAE+ +V  GI +R A  A++  
Sbjct: 214 ---FDELEEFNFYLQEKYARIEENE---VRYEEYLVDDAEIVMVAYGISSRVARSAVETA 267

Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLI 363
           R  GI  GLL+  T++PF  + I ++A    R    EM+ GQ+   +R  A+G  +V+L+
Sbjct: 268 RAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDIRM-ASGCRDVELV 326

Query: 364 SKIGGEVHTPMEIVDFIR 381
           +++GG +    ++++ IR
Sbjct: 327 NRMGGNLIELRDVLEKIR 344


>pir||A72519 probable 2-oxoacid--ferredoxin oxidoreductase alpha chain APE2126 -
           Aeropyrum pernix (strain K1) >gi|5105825|dbj|BAA81137.1|
           (AP000063) 644aa long hypothetical 2-oxoacid--ferredoxin
           oxidoreductase alpha chain [Aeropyrum pernix]
           Length = 644
           
 Score =  186 bits (467), Expect = 4e-46
 Identities = 129/359 (35%), Positives = 192/359 (52%), Gaps = 35/359 (9%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL-VDG------VVIQMEDEIASI 67
           G++ +A   ++ G R+ A YPITPAS+    +  +  L +DG       ++Q EDEIA++
Sbjct: 252 GNDVVAMGKVVGGVRYQAYYPITPASDESVLLEEFEGLKIDGESLGSIAILQTEDEIAAV 311

Query: 68  AAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQG 127
           +++IGA+  GA+A TATSGPGFSLM E +G+A   + P+V+   QRGGPSTG PT  SQ 
Sbjct: 312 SSVIGAALTGARASTATSGPGFSLMVEALGWAGKNDVPMVITYYQRGGPSTGLPTRGSQS 371

Query: 128 DIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVY 187
           D++ S++ +HG+   I+LS     EAF   I A+NLAE+++ PVI L D  + +M   V 
Sbjct: 372 DLLFSLFASHGEFPRIILSSGDHLEAFYDAIEAYNLAERFQMPVIHLLDKFLANMVASVP 431

Query: 188 IPEPDEIEIVNRKLPQNEEEAKLPFGD----PHGDFVPPMPIFGRGYRTYVTGLTHDERG 243
            P+   I     K+ + +   K P G     P    +   P+ G G  T+ TG  +DE G
Sbjct: 432 FPDWKAI-----KIDRGKTLFKAPTGPFKRFPRDQPLADRPVLGSGAITWYTGDENDEYG 486

Query: 244 RPRTVEREVHERVIRRIVEKIERNKK-DIFDYEARE--------LDDAEVAIVTTGIVAR 294
                   + E  + R+V    R KK +I D E  E         +DAEV +V  G V  
Sbjct: 487 -------HIDEDPVNRLVMYERRWKKMEIADREIPEDFRVKYYGDEDAEVLLVGWGSVKI 539

Query: 295 SALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGK--VERIYVPEMN-LGQLYHLV 350
            AL AI+ LRE+G+ A  L +  + P     + ++  +   +R+   E N LGQ   +V
Sbjct: 540 PALEAIERLREMGVNAAYLHLRMLSPLPKRRVSEVLSRFDADRVIAVEANYLGQASKIV 598


>pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha chain APE1473
           - Aeropyrum pernix (strain K1)
           >gi|5105157|dbj|BAA80471.1| (AP000061) 616aa long
           hypothetical 2-oxoacid--ferredoxin oxidoreductase ,
           alpha chain [Aeropyrum pernix]
           Length = 616
           
 Score =  184 bits (463), Expect = 1e-45
 Identities = 139/398 (34%), Positives = 206/398 (50%), Gaps = 44/398 (11%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL-----VDG-------------V 56
           G++ +A   I+ G      YPITP+S+     ALY+       +DG              
Sbjct: 218 GNDLVAMGKIVGGLGVITYYPITPSSD----EALYVEKHSYISIDGPLAEKLGYDKIAVA 273

Query: 57  VIQMEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGP 116
           ++QMEDE+ASI A++GA+ AGA+A T TSGPGFSLM E +  AV  E P+VV    R GP
Sbjct: 274 IVQMEDELASINAVLGAAAAGARASTTTSGPGFSLMNEAVSLAVEAEIPVVVTLWMRAGP 333

Query: 117 STGQPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSD 176
           STG PT   Q D++ SI+  HGD   IVL+     EAF   I+AFN AE+++TPVI L D
Sbjct: 334 STGMPTRTGQQDLLHSIFSGHGDAPKIVLASGDHVEAFYDAIKAFNWAEEFQTPVIHLLD 393

Query: 177 -----AEVGHMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYR 231
                + V   RE +   +P ++ I   KL  N   A     +   D + P    G    
Sbjct: 394 KYLASSMVSLAREDL---DPSKVPITRGKLLDN-PPADYRRYEVVEDGISPRARLGSA-T 448

Query: 232 TYVTGLTHDERG--RPRTVEREV----HERVIRRIVEKIERNKKDIFDYEARELDDAEVA 285
             +TGL HDE G      V RE+     ER  + I E+I   +K +   ++    +A VA
Sbjct: 449 MVITGLEHDEYGYATEDPVMREIMMFKRERKFKVIEERIPDEEKAVLHGDS----EASVA 504

Query: 286 IVTTGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LG 344
           +V+ G   +  L A++ LR+ G++A   ++  ++PF   L+E++   VE++ + E N LG
Sbjct: 505 LVSFGSTKQPILEALEMLRDEGVRARFAQVRLLYPFPGRLVEEMLEGVEKVIMVEQNLLG 564

Query: 345 QLYHLVREGANGKAEVKLISKIGGEVHTPMEIVDFIRR 382
           QL  L+R   + K +  ++ KI G      E+   ++R
Sbjct: 565 QLAMLLRAHTSIKPDSSIV-KINGRPLYSFEVAGAVKR 601


>pir||S22396 pyruvate synthase (EC 1.2.7.1) alpha chain [validated] -
           Halobacterium salinarum >gi|43498|emb|CAA45825.1|
           (X64521) pyruvate synthase [Halobacterium halobium]
           Length = 628
           
 Score =  176 bits (442), Expect = 4e-43
 Identities = 127/397 (31%), Positives = 192/397 (47%), Gaps = 25/397 (6%)

Query: 6   PVGKAD----FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQME 61
           P G  D     + G  AIA  AI AGCRF +GYP+TP ++ F  M   +P + GV  Q+E
Sbjct: 212 PTGSHDEPQVLMSGSHAIAYGAIDAGCRFISGYPMTPWTDAFTIMTQLLPDMGGVSEQVE 271

Query: 62  DEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQP 121
           DEIA+ A  +GAS AGAKAM+ +SG GF+LM E +G A MTETP+V+++ QR GPSTG P
Sbjct: 272 DEIAAAAMAVGASHAGAKAMSGSSGGGFALMSEPLGLAEMTETPLVLLEAQRAGPSTGMP 331

Query: 122 TLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGH 181
           T P Q D+   ++ + GD   +   P   +E ++ T  AF +A  Y+ PVILL D ++  
Sbjct: 332 TKPEQADLEHVLYTSQGDSHRVAFGPKDPKECYEQTRTAFEIAYDYQIPVILLYDQKLSG 391

Query: 182 MRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHG----------DFVPPMPIFGR-GY 230
               V     D     +     +E++      DP G          D V P  I G+ G 
Sbjct: 392 EYRNVDASFFDREPAADLGTTLSEDQIPDAPHDPTGKYHRYQHDVEDGVSPRTIPGQSGG 451

Query: 231 RTYVTGLTHDERGRPRTVEREVHERV--IRRIVEKIERNKKDIFDYEAREL---DDAEVA 285
           R   +G  H   G    +  +   RV  + R ++K+   + D+ + + +     +DA++ 
Sbjct: 452 RYLASGNEHWPNGH---ISEDTDNRVAQVERRLQKLAAIRDDLDERDQQTHYGDEDADIG 508

Query: 286 IVTTGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQ 345
           ++  G    +   A+  L + G     L I+ + PF           V+   V EM+  +
Sbjct: 509 LIAWGSQEGTVEEAVHRLNDDGNSVKALGISDLAPFPVAETRAFVDSVDEAIVVEMSSTK 568

Query: 346 LYHLVREGANGKAEVKLIS--KIGGEVHTPMEIVDFI 380
            +  + +   G    KL S  K  G    P EIV+ +
Sbjct: 569 QFRGLIQKEVGDIGGKLSSLLKYNGNPFEPAEIVEAV 605


>gb|AAG19514.1| (AE005043) putative 2-ketoglutarate ferredoxin oxidoreductase
           (alpha); KorA [Halobacterium sp. NRC-1]
           Length = 640
           
 Score =  176 bits (442), Expect = 4e-43
 Identities = 127/397 (31%), Positives = 192/397 (47%), Gaps = 25/397 (6%)

Query: 6   PVGKAD----FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQME 61
           P G  D     + G  AIA  AI AGCRF +GYP+TP ++ F  M   +P + GV  Q+E
Sbjct: 224 PTGSHDEPQVLMSGSHAIAYGAIDAGCRFISGYPMTPWTDAFTIMTQLLPDMGGVSEQVE 283

Query: 62  DEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQP 121
           DEIA+ A  +GAS AGAKAM+ +SG GF+LM E +G A MTETP+V+++ QR GPSTG P
Sbjct: 284 DEIAAAAMAVGASHAGAKAMSGSSGGGFALMSEPLGLAEMTETPLVLLEAQRAGPSTGMP 343

Query: 122 TLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGH 181
           T P Q D+   ++ + GD   +   P   +E ++ T  AF +A  Y+ PVILL D ++  
Sbjct: 344 TKPEQADLEHVLYTSQGDSHRVAFGPKDPKECYEQTRTAFEIAYDYQIPVILLYDQKLSG 403

Query: 182 MRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHG----------DFVPPMPIFGR-GY 230
               V     D     +     +E++      DP G          D V P  I G+ G 
Sbjct: 404 EYRNVDASFFDREPAADLGTTLSEDQIPDAPHDPTGKYHRYQHDVEDGVSPRTIPGQSGG 463

Query: 231 RTYVTGLTHDERGRPRTVEREVHERV--IRRIVEKIERNKKDIFDYEAREL---DDAEVA 285
           R   +G  H   G    +  +   RV  + R ++K+   + D+ + + +     +DA++ 
Sbjct: 464 RYLASGNEHWPNGH---ISEDTDNRVAQVERRLQKLAAIRDDLDERDQQTHYGDEDADIG 520

Query: 286 IVTTGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQ 345
           ++  G    +   A+  L + G     L I+ + PF           V+   V EM+  +
Sbjct: 521 LIAWGSQEGTVEEAVHRLNDDGNSVKALGISDLAPFPVAETRAFVDSVDEAIVVEMSSTK 580

Query: 346 LYHLVREGANGKAEVKLIS--KIGGEVHTPMEIVDFI 380
            +  + +   G    KL S  K  G    P EIV+ +
Sbjct: 581 QFRGLIQKEVGDIGGKLSSLLKYNGNPFEPAEIVEAV 617


>emb|CAB60189.1| (AL132824) putative oxidoreductase alpha-subunit [Streptomyces
           coelicolor]
           Length = 630
           
 Score =  175 bits (438), Expect = 1e-42
 Identities = 124/362 (34%), Positives = 184/362 (50%), Gaps = 21/362 (5%)

Query: 5   FPVGKADFIQGDEAIARAAILAGCR-----FYAGYPITPASEIFEAMALYMPLVDGV-VI 58
           FP G    I G+ A+A   I A  R     F   YPITPAS+I   ++ +     GV   
Sbjct: 242 FPPGTYRNISGNLALAYGLIAASRRADLPLFLGSYPITPASDILHELSKHKNF--GVRTF 299

Query: 59  QMEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPST 118
           Q EDEIA I A +GA++ GA A+T TSGPG +L  E IG AV  E P++VVD+QRGGPST
Sbjct: 300 QAEDEIAGIGAALGAAFGGALAVTTTSGPGVALKSETIGLAVSLELPLLVVDIQRGGPST 359

Query: 119 GQPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAE 178
           G PT   Q D++Q+++G +G+  + VL+P T  + FD  + A  +A  YRTPV LLSD  
Sbjct: 360 GLPTKTEQADLLQAMFGRNGEAPVAVLAPQTAADCFDAALEAARIALAYRTPVFLLSDGY 419

Query: 179 VGHMRERVYIPEPDEIEIVNRKLPQ-------NEEEAKLPF-GDPHGDFVPPMPIFGR-G 229
           + +  E   IPEPDE+  +  +  Q       +  E   P+  DPH     P  + G  G
Sbjct: 420 LANGSEPWRIPEPDELPDLTVQFAQGPNHTLDDGSEVFWPYKRDPH-TLARPWAVPGTPG 478

Query: 230 YRTYVTGLTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTT 289
               + G+   +     + +   H+ ++R    KI+     + D    + D A   ++  
Sbjct: 479 LEHRIGGIEKQDGTGNISYDPANHDFMVRTRQAKID--GITVPDLAVDDPDGARTLVLGW 536

Query: 290 GIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHL 349
           G        A++ +R+   +     +  + PF   L   +  + +++ VPEMNLGQL  L
Sbjct: 537 GSTYGPITAAVRRIRKEVGQIAQAHLRHLNPFPANL-GAVLERYDKVVVPEMNLGQLATL 595

Query: 350 VR 351
           +R
Sbjct: 596 IR 597


>emb|CAC08296.1| (AL392148) putative oxidoreductase [Streptomyces coelicolor]
           Length = 645
           
 Score =  175 bits (438), Expect = 1e-42
 Identities = 124/362 (34%), Positives = 184/362 (50%), Gaps = 21/362 (5%)

Query: 5   FPVGKADFIQGDEAIARAAILAGCR-----FYAGYPITPASEIFEAMALYMPLVDGV-VI 58
           FP G    I G+ A+A   I A  R     F   YPITPAS+I   ++ +     GV   
Sbjct: 257 FPPGTYRNISGNLALAYGLIAASRRADLPLFLGSYPITPASDILHELSKHKNF--GVRTF 314

Query: 59  QMEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPST 118
           Q EDEIA I A +GA++ GA A+T TSGPG +L  E IG AV  E P++VVD+QRGGPST
Sbjct: 315 QAEDEIAGIGAALGAAFGGALAVTTTSGPGVALKSETIGLAVSLELPLLVVDIQRGGPST 374

Query: 119 GQPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAE 178
           G PT   Q D++Q+++G +G+  + VL+P T  + FD  + A  +A  YRTPV LLSD  
Sbjct: 375 GLPTKTEQADLLQAMFGRNGEAPVAVLAPQTAADCFDAALEAARIALAYRTPVFLLSDGY 434

Query: 179 VGHMRERVYIPEPDEIEIVNRKLPQ-------NEEEAKLPF-GDPHGDFVPPMPIFGR-G 229
           + +  E   IPEPDE+  +  +  Q       +  E   P+  DPH     P  + G  G
Sbjct: 435 LANGSEPWRIPEPDELPDLTVQFAQGPNHTLDDGSEVFWPYKRDPH-TLARPWAVPGTPG 493

Query: 230 YRTYVTGLTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTT 289
               + G+   +     + +   H+ ++R    KI+     + D    + D A   ++  
Sbjct: 494 LEHRIGGIEKQDGTGNISYDPANHDFMVRTRQAKID--GITVPDLAVDDPDGARTLVLGW 551

Query: 290 GIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHL 349
           G        A++ +R+   +     +  + PF   L   +  + +++ VPEMNLGQL  L
Sbjct: 552 GSTYGPITAAVRRIRKEVGQIAQAHLRHLNPFPANL-GAVLERYDKVVVPEMNLGQLATL 610

Query: 350 VR 351
           +R
Sbjct: 611 IR 612


>pir||F70864 probable oxidoreductase alpha subunit - Mycobacterium tuberculosis
           (strain H37RV) >gi|2791495|emb|CAA16032.1| (AL021246)
           hypothetical protein Rv2455c [Mycobacterium
           tuberculosis]
           Length = 653
           
 Score =  169 bits (424), Expect = 5e-41
 Identities = 123/385 (31%), Positives = 191/385 (48%), Gaps = 18/385 (4%)

Query: 6   PVGKADFIQGDEAIARAAILAGCR-----FYAGYPITPASEIFEAMALYMPLVDGVVIQM 60
           P G+   I G+ A+A   ++AG           YPITPAS+I   ++ +    + V  Q 
Sbjct: 247 PPGEYRQISGNTALAYGIVVAGQLAGLPVVLGSYPITPASDILHELSKHKNF-NVVTFQA 305

Query: 61  EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120
           EDEI  I A +GA++ GA  +T+TSGPG SL  E +G  VMTE P++V+DVQRGGPSTG 
Sbjct: 306 EDEIGGICAALGAAYGGALGVTSTSGPGISLKSEALGLGVMTELPLLVIDVQRGGPSTGL 365

Query: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180
           PT   Q D++Q+++G +G+  + VL+P +  + F+  + A  +A  Y TPVILLSD  + 
Sbjct: 366 PTKTEQADLLQALYGRNGESPVAVLAPRSPADCFETALEAVRIAVSYHTPVILLSDGAIA 425

Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGR-GYRTYVTGLTH 239
           +  E   IP+ + +  +     +  E  + P+            I G  G    + GL  
Sbjct: 426 NGSEPWRIPDVNALPPIKHTFAKPGEPFQ-PYARDRETLARQFAIPGTPGLEHRIGGLEA 484

Query: 240 DERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARE-LDDAEVAIVTTGIVARSALR 298
                  + E   H+ ++R    KI+     + D E  +   DAE+ ++  G        
Sbjct: 485 ANGSGDISYEPTNHDLMVRLRQAKID--GIHVPDLEVDDPTGDAELLLIGWGSSYGPIGE 542

Query: 299 AIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGK- 357
           A +  R  G K     +  + PF   L E +  +  ++  PE+NLGQL  ++R    GK 
Sbjct: 543 ACRRARRRGTKVAHAHLRYLNPFPANLGE-VLRRYPKVVAPELNLGQLAQVLR----GKY 597

Query: 358 -AEVKLISKIGGEVHTPMEIVDFIR 381
             +V+ ++K+ G      EI  FIR
Sbjct: 598 LVDVQSVTKVKGVSFLADEIGRFIR 622


>emb|CAC11404.1| (AL445063) probable pyruvate ferredoxin oxidoreductase, alpha
           subunit [Thermoplasma acidophilum]
           Length = 588
           
 Score =  167 bits (419), Expect = 2e-40
 Identities = 115/381 (30%), Positives = 189/381 (49%), Gaps = 9/381 (2%)

Query: 5   FPVGKADF-IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDE 63
           F  GK  + I G  A+A  A+  G + Y  YP+TPAS     +A +       V   EDE
Sbjct: 199 FKFGKKKYMISGGMAVALGAVAGGLKMYVAYPMTPASSALHFLAQHAKKYGVFVKIPEDE 258

Query: 64  IASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTL 123
           I++I  +IGA++AG +AMT +SG GF+LM E +G + MTE P+V+ + QR GPSTG PT 
Sbjct: 259 ISAINTVIGANYAGVRAMTGSSGGGFALMTEAVGLSGMTEVPLVIYEAQRPGPSTGLPTK 318

Query: 124 PSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMR 183
             QGD+ Q +  + GD   IV +P  ++EAF  T  A N+AEKY+TPV ++SD  +    
Sbjct: 319 TEQGDLNQVLGASQGDFPRIVFAPGDIEEAFYLTREAMNIAEKYQTPVFVMSDLYLAEHY 378

Query: 184 ERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGR-GYRTYVTGLTHDER 242
           + +   + +       +   NE++ K       G  + P  I G+ G         H+E 
Sbjct: 379 DTIDSFDLNFNIDHGLRAKDNEQDYKRYLITETG--ISPRAIPGQPGNMHNEDSDEHNEY 436

Query: 243 G---RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRA 299
           G          +   +++++ + K++   +++       + DAE  I+  G    +   A
Sbjct: 437 GDVVSDAVTNPQDRIKMMQKRMRKLDTYIEEMKPTPTYRIQDAEYVIIQWGSTKGAVEEA 496

Query: 300 IKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAE 359
           I  LR  GIK G +++  ++P + ++   +  + + + V     GQL   +   A    +
Sbjct: 497 IDILRAKGIKIGAIEVKNVFPLNPDIGTLLKNRKKILAVENNYSGQLSKYI--AAQFLVK 554

Query: 360 VKLISKIGGEVHTPMEIVDFI 380
            +LI+K  GE   P  + + I
Sbjct: 555 PELITKYDGEAFYPNALAEEI 575


>emb|CAC11904.1| (AL445065) probable 2-oxoacid ferredoxin oxidoreductase, alpha
           chain [Thermoplasma acidophilum]
           Length = 629
           
 Score =  167 bits (419), Expect = 2e-40
 Identities = 113/353 (32%), Positives = 176/353 (49%), Gaps = 20/353 (5%)

Query: 6   PVGKADFIQGDEAIARAAILAGCRFYAGYPITPASEI------------FEAMALYMPLV 53
           P  +   + G++A A   +L G RF   YPITPAS+              +  A  +   
Sbjct: 226 PTPRKLLLTGNDASALGKLLGGLRFQTYYPITPASDESTTIEEHQNIKWLDKEAANLKKG 285

Query: 54  DGVVIQMEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQR 113
             V++Q EDE++++   IG +  G ++ TATSGPGFSLM E + +A M E P+VV   +R
Sbjct: 286 GVVIVQTEDELSAVNMAIGGALTGVRSATATSGPGFSLMAEGLSFAGMDEVPLVVTFYER 345

Query: 114 GGPSTGQPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVIL 173
           GGPSTG PT   Q D++ ++   HG++  IV S  TV E      +A N A KY+ PVI 
Sbjct: 346 GGPSTGLPTRNGQSDLLFALNAGHGEYPRIVFSSGTVDECIYDAAKALNYAAKYQMPVIH 405

Query: 174 LSDAEVGHMRERVYIPEPDEIEIVNRKLPQNEEEAK-LPFGDPHGDFVPPMPIFGRGYRT 232
           L D  + +  + +   + D I+I   KL +  ++ K       +G  V P    GR    
Sbjct: 406 LIDKNLANTLDLISKVDLDRIKIETVKLAKEGDDVKRYDLNTDNG--VSPYTTMGRNI-F 462

Query: 233 YVTGLTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEAREL---DDAEVAIVTT 289
           ++TG  HDE G   T + ++ +R++ +  +K+E   ++I   E   L    +A++  VT 
Sbjct: 463 WMTGDEHDELGHV-TEDSDIRDRMMEKRFKKLETADREIPIDEKAVLIGEKEADITFVTW 521

Query: 290 GIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342
           G      L  I++L+E GI A LL +    PF  E ++ +      +   E N
Sbjct: 522 GSQKGPILDVIEDLKEEGISANLLYLKMFSPFPTEFVKNVLSSANLVIDVESN 574


>gb|AAK42926.1| 2-oxoacid--ferredoxin oxidoreductase, alpha chain [Sulfolobus
           solfataricus]
           Length = 632
           
 Score =  164 bits (412), Expect = 1e-39
 Identities = 125/349 (35%), Positives = 176/349 (49%), Gaps = 23/349 (6%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASE--IFEAMALYMPLVDG----------VVIQM 60
           + G+ A A   I  G RF + YPITPAS+  +F      +  VD           VV+Q 
Sbjct: 233 LDGNTAAAIGKIYGGLRFQSYYPITPASDESVFIEAHQTVFTVDPKTGEKRKSTIVVVQA 292

Query: 61  EDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQ 120
           EDE+A+I    GA+  G +A TATSGPGFSLM E +G+A M E P+V+    RGGPSTGQ
Sbjct: 293 EDELAAINMASGAALTGVRAATATSGPGFSLMVEGMGWAGMNEVPVVITYYIRGGPSTGQ 352

Query: 121 PTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVG 180
           PT  SQ D+M ++   HG+   IV++     EAF     A NLA+KY+TPVI L D  + 
Sbjct: 353 PTRTSQADLMFALNAGHGEFPRIVIASGDHVEAFHDGTWALNLAQKYQTPVIHLVDKALA 412

Query: 181 HMRERVYIPEP----DEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTG 236
           +      IP+     + I I   K+  N    +L   +   D + P    G   R + TG
Sbjct: 413 NSYS--IIPKKTLGMENIRIEKGKIVINTNTPELKRFEITEDGISPFAPLGTA-RVHYTG 469

Query: 237 LTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEAREL---DDAEVAIVTTGIVA 293
             HDE G       E  E++  + ++K+    K+I +     +    D++VAI+T G   
Sbjct: 470 DEHDEYGFIAEAS-ENREKMYEKRIKKLMTADKEIPEESRVNVYGNTDSKVAIITWGSPK 528

Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342
            + L A++EL   GIK  L++I    PF   L+ K+    E I   E N
Sbjct: 529 GAILDAMEELENEGIKPMLIQIRMFSPFPKNLMRKLLNGKEFIIDVESN 577


>pir||B72288 2-oxoacid ferredoxin oxidoreductase, alpha subunit - Thermotoga
           maritima (strain MSB8)
           >gi|4981713|gb|AAD36240.1|AE001773_9 (AE001773)
           2-oxoacid ferredoxin oxidoreductase, alpha subunit
           [Thermotoga maritima]
           Length = 558
           
 Score =  162 bits (405), Expect = 8e-39
 Identities = 111/343 (32%), Positives = 178/343 (51%), Gaps = 13/343 (3%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72
           + G EA+   AI  GC F + YP++P++ +   +A +      VV Q EDEIA++  IIG
Sbjct: 195 LNGAEAVGLGAIAGGCNFVSSYPMSPSTSVLVFLAQHKNDFGIVVEQAEDEIAAMNMIIG 254

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A +AGA+ +  TSG GF+LM+E +  A M E+P V+   QR GP+TG PT   QGD+  +
Sbjct: 255 AWYAGARGLVTTSGGGFALMEEALSLAGMIESPAVIHLAQRPGPATGLPTRTEQGDLNLA 314

Query: 133 IWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPD 192
           ++  HGD   ++ +P  V+EAF  T +AFN+A+KY+ PV +L+D  +      +   + +
Sbjct: 315 LYAGHGDFPRVIYAPGNVEEAFYLTQKAFNVADKYQVPVFVLTDQYLVDSYYNLPGFDLN 374

Query: 193 EIEIVNRKLPQNEEEAKLPFGDPHGDFVPP--MPIFGRGYRTYVTGLTHDERGRPRTVER 250
           E+++    +    +  +    +   D + P  +P +G G    V    HDE G   T + 
Sbjct: 375 ELKVEKHFIKTTRDYIRYAITE---DGISPRGIPGYGEGL-VRVDSDEHDEFGH-ITEDF 429

Query: 251 EVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKA 310
               R++ + + K E  KK+I   +    ++  V +V  G    S L  IKE  E     
Sbjct: 430 NTRVRMVNKRLRKGETLKKEIVKPKLIGDENYRVLLVAWG----STLEPIKEAIEGLDGV 485

Query: 311 GLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVRE 352
            LL  + +WP D E +     K E++   E N  GQ  +L+R+
Sbjct: 486 ALLHFSQVWPID-ESVATYFEKAEKVVAVEGNATGQFANLIRQ 527


>emb|CAA75641.1| (Y15464) ferredoxin oxidoreductase-like (gamma and alpha subunit in
           fusion) [Thermus thermophilus]
           Length = 617
           
 Score =  152 bits (381), Expect = 5e-36
 Identities = 116/372 (31%), Positives = 190/372 (50%), Gaps = 19/372 (5%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPASE--IFEAMALYMPLVDGVVIQMEDEIASIAA 69
           ++ G +A A   +  G RF   YPI+PA++  +F     ++P  D  V+Q EDEIA++  
Sbjct: 233 YLTGAQAAALGKLAGGLRFQTYYPISPATDESVFLEAHTHLPGADVAVVQTEDEIAAVNM 292

Query: 70  IIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDI 129
            +GA+ AGAKA TATSGPGFSLM E +G+A M E P+VV   QRG      PT   QGD+
Sbjct: 293 AVGAALAGAKAATATSGPGFSLMAEGLGFAGMIEAPLVVTLYQRGRAQHRLPTRTEQGDL 352

Query: 130 MQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIP 189
           M +I G HG++  +VL+   + +AF    +A   A +Y+T V+ L D  +  + + +   
Sbjct: 353 MFAIRGGHGEYPRLVLASGDILDAFLDAQKALAWAWRYQTVVVHLLDKFLASLAQSL--- 409

Query: 190 EPDEIEIVN----RKLPQNEEEAKLPFGDPHGDFVPP-MPIFGRGYRTYVTGLTHDERGR 244
             + +++++    ++L   E         P  D + P +PI   G   ++T   HD  G 
Sbjct: 410 PKEALKVLSLDGEKRLSPREGFGPYQRYAPGEDGLSPFIPIGTPGGFYWMTSDEHDPLGH 469

Query: 245 PRTVEREVHERVIRRIVEKIERNKKDI-FDYEARELDDAEVAIVTTGIVARSALRAIKEL 303
             T + E+ E  + + +EK+E  +K+I  + +     D EV ++  G V  + L A+  L
Sbjct: 470 -ITEDVELRELQMEKRMEKLELARKEIPLEDQYTLFRDGEVLVLGWGTVKGTLLEALDHL 528

Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKAEVKLI 363
             +    G L +  +WPF   +   + GK   + V     GQL  LV++    +   +++
Sbjct: 529 EGV----GYLHLRLLWPFP-RIAPLLEGKT-LVTVEHNYSGQLADLVQQETLKRVHHRVV 582

Query: 364 SKIGGEVHTPME 375
            K  G   +P+E
Sbjct: 583 -KYNGRAPSPLE 593


>pir||JC4919 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
           [validated] - Sulfolobus sp. (strain 7)
           >gi|1565183|dbj|BAA10898.1| (D64024)
           2-oxoacid:ferredoxin oxidoreductase subunit alpha
           [Sulfolobus sp. 7]
           Length = 632
           
 Score =  152 bits (381), Expect = 5e-36
 Identities = 126/380 (33%), Positives = 182/380 (47%), Gaps = 35/380 (9%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPAS------EIFEAMALYMPLVDG------VVIQ 59
           ++ G+ A+A   I  G RF + YPITPAS      E  + + +  P+         VV+Q
Sbjct: 231 WLDGNTAVAIGKIYGGVRFQSYYPITPASDESVYIEAHQDVLMEDPITGDKKKGTIVVVQ 290

Query: 60  MEDEIASIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTG 119
            EDE+A+I   IGA+  G +A TATSGPGFSLM E +G+A M E P+V+    RGGPSTG
Sbjct: 291 AEDELAAINMAIGAALTGVRAATATSGPGFSLMVEGLGWAGMNEVPVVITYYIRGGPSTG 350

Query: 120 QPTLPSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV 179
            PT  +Q D++  I+  HG+   IVL+     EAF   I A NLAEKY+TPVI L +  +
Sbjct: 351 LPTRTAQSDLIFPIFAGHGEFPKIVLASGDHAEAFKDAIWALNLAEKYQTPVIHLVEKTL 410

Query: 180 GHMRERVYIP--EPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGL 237
            +    +     E D+++    K+ ++ + +   F     D + P    G+    Y TG 
Sbjct: 411 ANSYSTIPYEELELDKLKAERGKIVESGDISYKRFKFTE-DGISPRAFLGKA-TMYYTGD 468

Query: 238 THDERGRPRTVEREVHERVIRRIVEKIERNKK-DIFDYEARELDDAEV--------AIVT 288
            H+E G        + E V+ R +   +R KK ++ D E  E    ++         I+T
Sbjct: 469 EHNEEG-------HISEDVVNRTMMYEKRMKKLEVADKEIPEESRVKIYGDLNSRNLIIT 521

Query: 289 TGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYH 348
            G      LR I  L E      LL+I    PF   L+ K+    ++I   E N      
Sbjct: 522 WG-SPTGVLRDI--LEESNFDFTLLQIRMFSPFPKNLVSKLMEGRDKIITVEGNYLAQTS 578

Query: 349 LVREGANGKAEVKLISKIGG 368
           L+ +   GK     I K  G
Sbjct: 579 LLVKMYTGKDVTNSILKWNG 598


>pir||G69170 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621610|gb|AAB85042.1| (AE000836)
           2-oxoacid:ferredoxin oxidoreductase, alpha subunit
           [Methanobacterium thermoautotrophicum]
           Length = 512
           
 Score =  142 bits (354), Expect = 7e-33
 Identities = 107/344 (31%), Positives = 175/344 (50%), Gaps = 19/344 (5%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72
           + G EA+    I  GCRF + YP+TP++ +   ++      D V  Q EDEIA+I   +G
Sbjct: 151 LNGTEAVGIGCIAGGCRFMSSYPMTPSTPLQVFISENAAEFDMVFEQAEDEIAAINMCLG 210

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           AS+AGA+++ ATSG GF+LM+E +G A M ETP+V+   QR GP+ G PT  +Q D+  +
Sbjct: 211 ASYAGARSLVATSGSGFALMEEAVGLAGMIETPVVIYIGQRPGPAVGLPTRTAQEDLNLA 270

Query: 133 IWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVY-IPEP 191
           ++   G+    +L+P  +++A +    AFNLA++Y+ PV LLSD    ++ +  Y +P P
Sbjct: 271 LYAGPGEFPRAILAPGKLEDAPEIAAHAFNLADRYQIPVFLLSDQ---YLADLYYDLPSP 327

Query: 192 DEIEIVNRKLPQN-EEEAKLPFGDPHGDFVPPMPIFGRGYRTY-VTGLTHDERGRPRTVE 249
              E  +  + +  E   +  F     D + P  I G G  T  V    HDE G   T +
Sbjct: 328 QIGEEPSYHITRTWEGYRRFEF---TADGISPRGIPGYGSGTVRVDSDEHDEEGL-ITED 383

Query: 250 REVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKE-LRELGI 308
            +V  R++ +   ++E  K D    E     D   A++  G    S    ++E +   G 
Sbjct: 384 LDVRRRMVEKRNLRLEMLKDDTLKPEV--YGDNSSALICWG----STYWLVREAIESSGA 437

Query: 309 KAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL-GQLYHLVR 351
              ++  + ++P   + +E +    +R  V E N  GQ   L++
Sbjct: 438 DVSMVHFSQVYPLPHDTLE-LLESFDRTAVVENNYRGQFADLLK 480


>gi|11498355 2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA)
           [Archaeoglobus fulgidus] >gi|7433693|pir||E69343
           2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha
           chain orA - Archaeoglobus fulgidus
           >gi|2649863|gb|AAB90491.1| (AE001053) 2-oxoacid
           ferredoxin oxidoreductase, subunit alpha (orA)
           [Archaeoglobus fulgidus]
           Length = 532
           
 Score =  131 bits (326), Expect = 1e-29
 Identities = 120/389 (30%), Positives = 180/389 (45%), Gaps = 52/389 (13%)

Query: 9   KADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIA 68
           K + + G  AIA   + AG +FY  YP+TPAS I   +A     V    +Q E+EIA+I 
Sbjct: 178 KKELVSGARAIAEGMLAAGLKFYYAYPMTPASPILHILAADSRCV---ALQPENEIAAIM 234

Query: 69  AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128
             IG+++ G +A   TSG GF+LM E+I  A M E P++++  QR GPSTG  T  +Q D
Sbjct: 235 MAIGSAFGGERAAVGTSGGGFALMSESISLAGMAEVPVLIILAQRSGPSTGMATYTAQQD 294

Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188
           +  ++   HG+  LIV SP T+++++       NLA +++TP ILL++    H+ E +  
Sbjct: 295 LYFALNPAHGEFPLIVASPITIEDSYRLAGELLNLAWQFQTPAILLTEK---HITESLAT 351

Query: 189 PEPD-----EIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIF---GRGYRTYVTGLTHD 240
            + +     E+EI   K    +  A    G     +  P  IF      +  Y       
Sbjct: 352 AKLEGVVKREVEIFREKGELFKRYAITESG--ISPYAAPPAIFKANSNEHDEYGFATDDA 409

Query: 241 ERGRPRTVEREVHERVIRRIVEKIE-----RNKKDIFDYEARELDDAEVAIVTTGIVARS 295
           E       +R   E  IRR+V  +      +N KD               IVT G    S
Sbjct: 410 ETATKMYAKRMRKEEEIRRVVANLNPYVVVKNGKD--------------WIVTWG----S 451

Query: 296 ALRAIKEL-RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVREG 353
              A+KE+  ELG     ++   + P     + KI+G V   +  E N  G L  L+   
Sbjct: 452 NFGAVKEVAEELGFSVAAIRY--MRPL---FLPKISGNV---FCVECNYTGLLARLIE-- 501

Query: 354 ANGKAEVKLISKIGGEVHTPMEIVDFIRR 382
           A G  EVK I +  G   TP E+ + + +
Sbjct: 502 AEG-VEVKRILRWDGRPFTPEEVREEVEK 529


>gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA)
           [Archaeoglobus fulgidus] >gi|7449955|pir||D69506
           probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC
           1.2.7.-) alpha chain AF2053 [similarity] - Archaeoglobus
           fulgidus >gi|2648476|gb|AAB89196.1| (AE000961)
           2-ketoisovalerate ferredoxin oxidoreductase, subunit
           alpha (vorA) [Archaeoglobus fulgidus]
           Length = 366
           
 Score =  116 bits (287), Expect = 5e-25
 Identities = 111/387 (28%), Positives = 164/387 (41%), Gaps = 57/387 (14%)

Query: 8   GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIA 65
           G    +  +EAIA A  LA     A YPITP S I E ++  +    +D   +++E E +
Sbjct: 12  GMKKLLTSNEAIAEAVKLAKPDVIAAYPITPQSPIVEKLSEMVDSGELDSRFVRVESEHS 71

Query: 66  SIAAIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPS 125
           ++  +IGA+ AGA+  TATS  G + M E   +A  +  PIV+    R   S G P    
Sbjct: 72  AMGVVIGAATAGARVFTATSSHGLAYMYEMCWWAAGSRLPIVMALAAR---SIGAP---- 124

Query: 126 QGDIMQSIWGTHGDH---------SLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSD 176
                   W  HGDH           I+      QEAFD T+ AF L+E+   PV +  D
Sbjct: 125 --------WNIHGDHLDLMAMRDLGWIISVAENAQEAFDMTLNAFMLSEEVNIPVAVAID 176

Query: 177 AEVGHMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTG 236
                M     + E  E+EI     P+ +    LP  D   + V     FG    T    
Sbjct: 177 GFT--MSHTAEVVEVREVEIP----PRKQAYRILPGMDVALNAV----TFGEARMTARYD 226

Query: 237 LTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSA 296
           L  D       +E+E    V                  E   L+DA+ A+V TG ++   
Sbjct: 227 LAKDLENSAELIEKEYGGLV------------------ERYRLEDADYAVVVTGGLSGDV 268

Query: 297 LRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHL-VREGAN 355
             A+  LRE G+K G+L++  I PF  + ++ +  +V  + V   N      L V   A 
Sbjct: 269 KDAVDMLREEGVKMGVLRLKFIRPFPKKAVKSLPSQV--LVVDRANTDLRGTLSVEVAAC 326

Query: 356 GKAEVKLISKIGGEVHTPMEIVDFIRR 382
           G   V +++ IGG   T  E+   ++R
Sbjct: 327 GVENVNVVAGIGGRYPTVEELYSCLKR 353


>dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase alpha subunit
           [Hydrogenobacter thermophilus]
           Length = 400
           
 Score =  110 bits (272), Expect = 3e-23
 Identities = 106/385 (27%), Positives = 165/385 (42%), Gaps = 51/385 (13%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMA-LYMPLVDGVVIQMEDEIASIAAI 70
           F+ G EA+  A   A       YPITP SE    +  L++    GV  + E E   ++ I
Sbjct: 32  FMTGSEAVKEAVKRASVDASVSYPITPQSEAAHLIGELWVEGYVGVYFRGESEFGVMSEI 91

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRG--GPSTGQPTLPSQGD 128
            G + AGA+ +T TSGPG     EN      T  P+ +V + RG   P + QP       
Sbjct: 92  AGCALAGARTITTTSGPGTLRAMENFPMWAGTRIPVQLVLMARGVNAPLSIQPDNLEVSF 151

Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEK--YRTPVILLSDAE-VGHMRER 185
           ++        D   ++    T Q+ FD  +  F +AE+     PVI + D   V H RE 
Sbjct: 152 LL--------DTGCMIWYAETAQDLFDMILAGFVVAEQPDVHVPVITVVDGFFVSHTRET 203

Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGD---PHGDFVPPMPIFGRGYRTYVTGLTHD-- 240
           V +P PD+I +     P N   A +P  D   P G F+    +    Y +Y T  +    
Sbjct: 204 VMLP-PDDIALP----PYNPYRAPMPVIDAEVPPGRFLRDPFVMKSNYISYATHASWQWE 258

Query: 241 -----ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARS 295
                ER RP        +  +R ++E                  +A++  V  G  +  
Sbjct: 259 VRAAIERSRPYA------KHYLRGLIEHFGD-------------PEADLVFVACGTASAQ 299

Query: 296 ALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVREGA 354
           A  A++ L + GI A ++K+ TI PF  E + +     + I+VPE N +G L   VR   
Sbjct: 300 AKEAVRMLEDEGISARVVKLKTIRPFPIEELREATKGAKYIFVPEFNVVGWLEREVRRYL 359

Query: 355 NGKAEVKLIS--KIGGEVHTPMEIV 377
            G +  ++I   ++ G +  P E++
Sbjct: 360 YGHSSAEIIGAPRVAGGMTMPAEVI 384


>sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|7449945|pir||E69099 pyruvate synthase (EC
           1.2.7.1) alpha chain - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622870|gb|AAB86209.1| (AE000929) pyruvate
           oxidoreductase, alpha subunit  [Methanobacterium
           thermoautotrophicum]
           Length = 383
           
 Score =  106 bits (263), Expect = 4e-22
 Identities = 104/384 (27%), Positives = 168/384 (43%), Gaps = 38/384 (9%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV----IQMEDEIASIA 68
           I  ++A+A AA LA  +    YPITP + I E +A ++   DG +    I++E E ++++
Sbjct: 6   ISANQAVAEAAKLAKPKVIPVYPITPQTSISEYLAKFV--ADGELKAEYIRVESEHSAMS 63

Query: 69  AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128
           A +GAS AG +  TATS  G +LM E +  A     PIV+ +  R   +     L    D
Sbjct: 64  ACVGASGAGVRVFTATSSQGLALMHEIVYAAAGLRNPIVMANANRALSA----PLSIWND 119

Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEK---YRTPVILLSDAEVGHMRER 185
              SI     D   + +   + QEA D  + ++ ++E        ++ L    + H  E 
Sbjct: 120 QQDSI--AERDSGWMQIYVESGQEALDSVLLSYRVSEDRDVLLPSMVCLDGFILTHTVEP 177

Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPH--GDFVPPMPIFGRGYRTYVTGLTHDERG 243
           V IP  ++++     LP+ + +  L   +P   G F  P          Y+      E+ 
Sbjct: 178 VDIPSQEDVDSF---LPEFQPQVMLDPDEPMSLGTFTDP--------DYYMEARYEVEKA 226

Query: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303
             R+  R++ ER  R   E   R    + +Y     +DAE+ +V  G V  +    I EL
Sbjct: 227 MERS--RKIIERACREFSEMFGREYGLVEEYRC---EDAEIILVAMGSVCSTLREVIDEL 281

Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL-----GQLYHLVREGANGKA 358
           R+ G   GLLK+    PF  E I+       ++ V + N+     G LY  +      + 
Sbjct: 282 RDKGKAVGLLKVRVHRPFPAEEIKSAVRNASKVAVLDKNITFSVGGALYTEISALLRDRE 341

Query: 359 EVKLISKIGGEVHTPMEIVDFIRR 382
               I  +GG   TP  I + +RR
Sbjct: 342 VYGFIVGLGGRDITPAHIEEIVRR 365


>pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus
           >gi|2983644|gb|AAC07211.1| (AE000728) ferredoxin
           oxidoreductase alpha subunit [Aquifex aeolicus]
           Length = 404
           
 Score =  106 bits (261), Expect = 6e-22
 Identities = 108/386 (27%), Positives = 164/386 (41%), Gaps = 52/386 (13%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMA-LYMPLVDGVVIQMEDEIASIAAI 70
           FI G EA+  AA  A       YPITP SE    +  L+     GV  + E E   ++ +
Sbjct: 35  FITGSEAVKEAAKRASVDASISYPITPQSEAAHMLGELWREGYIGVYFRGESEFGVMSEV 94

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRG--GPSTGQPTLPSQGD 128
            G + AGA+ +T TSGPG     E       +  PI +V + RG   P + QP       
Sbjct: 95  AGCAMAGARTITTTSGPGTMRAMEVFPMWAGSRLPIQLVLMARGINSPLSIQPDNLEISF 154

Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEK--YRTPVILLSDA-EVGHMRER 185
           ++        D   +V    T QE FD  I  F +AE+     P+I   D   + H RE 
Sbjct: 155 LL--------DTGCMVWHAETAQELFDMIIAGFVVAEQPDVHVPIITAIDGFFISHTREA 206

Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGD---PHGDFVPPMPIFGRGYRTYVTGLTHD-- 240
           VY+P P++I +     P N  +A +P  D   P G F+    +    Y +Y T  +    
Sbjct: 207 VYLP-PEDIALP----PYNPYKAPMPPIDMEMPPGRFMRDPFVMKSNYISYATHASWQFE 261

Query: 241 -----ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARS 295
                ER RP        +  +R +VE                  + EV  + +G  A  
Sbjct: 262 VRAAIERSRPYA------KHYLRGLVEHFGD-------------PEGEVLFIASGTAAAQ 302

Query: 296 ALRAIKEL-RELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN-LGQLYHLVREG 353
           A  A + L  E GIKA +L++ T+ PF  E + +     + I++PE N +G L   V+  
Sbjct: 303 AKEATQILIHEEGIKARVLRLKTLRPFPTEEVREAVKGAKYIFIPEFNVVGWLEREVKRA 362

Query: 354 ANGKAEVKLIS--KIGGEVHTPMEIV 377
             G  ++ +    ++GG +  P E +
Sbjct: 363 LYGYTDIPIFGTPRVGGGMTMPPEFI 388


>gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
           alpha chain) (porA-2) [Sulfolobus solfataricus]
           Length = 400
           
 Score =  104 bits (258), Expect = 1e-21
 Identities = 92/326 (28%), Positives = 149/326 (45%), Gaps = 46/326 (14%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70
           I G+EA+A    LA       YPITP + I E +A       ++  ++++E E +++AA 
Sbjct: 6   ISGNEAVALGVKLARVGVTGIYPITPQTTIIEKLAEMRAKGEIETEIVRVESEHSAMAAT 65

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
            GA+  G +A TAT+  G   M E + +   +  P+V+V    G  + G P         
Sbjct: 66  FGAALGGVRAFTATASQGLLYMHEMVWWVAGSRVPVVMV---VGTRAVGAP--------- 113

Query: 131 QSIWGTHGDHS------LIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GH 181
            +IW  H D +       I+   S  QEA D T++AF ++E  R   P+++  D  +  H
Sbjct: 114 WNIWNEHTDFTSERDSGWIMAFASNPQEALDLTLQAFRISEDERVFLPMMIGMDGFILSH 173

Query: 182 MRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDP--HGDFVPPMPIFGRGYRTYVTGLTH 239
            +  V IP+ D+++     LP   +   +   DP   G+  PP      GY      +  
Sbjct: 174 TKTNVLIPDQDQVDDF---LPPRRQPYVIDPEDPVGMGNIFPP-----EGYMRLRESIDL 225

Query: 240 DERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYE----ARELDDAEVAIVTTGIVARS 295
             R           E VI+ I  +  +    + DY     + +L+DA+ A+V  G  A  
Sbjct: 226 ALRN---------SEDVIKEIGREYNKKINPLGDYSTLNVSYKLEDADYAVVLMGAWAGD 276

Query: 296 ALRAIKELRELGIKAGLLKINTIWPF 321
           A+ A+  LRE GIK G+L+I  + P+
Sbjct: 277 AMEAVDTLREKGIKIGMLRIRYLRPW 302


>gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
           alpha chain) (porA-1) [Sulfolobus solfataricus]
           Length = 385
           
 Score =  101 bits (249), Expect = 2e-20
 Identities = 99/339 (29%), Positives = 153/339 (44%), Gaps = 45/339 (13%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVD--GVVIQMEDEIASIAAIIG 72
           G+ A+A A   A  +  A +PITP + + E ++ Y+   +    +I++E E +++A+I G
Sbjct: 13  GNHAVAYAVKQAKPKVLAVFPITPQTTMLEKLSEYISSEELKAELIKVESEHSALASIYG 72

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A+ AGA+  TATS  G   M E I +A     PIV     R   +  +P          S
Sbjct: 73  AALAGARVFTATSSQGLLYMTEMIYWAGGQRVPIVAAVATR---AIAEP---------WS 120

Query: 133 IWGTHGDH------SLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMR 183
           IW  H D         I +    VQEA+D TI+AF ++E  R   PV++  D  +  H  
Sbjct: 121 IWDDHQDFVSKRDAIWIQIMAENVQEAYDMTIQAFRISEDERVILPVMMGFDGFILTHTM 180

Query: 184 ERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDP--HGDFVPPMPIFGRGYRTYVTGLTHDE 241
           ER+ + E +E   V+  LP  +    + F DP   G    P       Y           
Sbjct: 181 ERIEVLEDNE---VDNFLPPRQFNL-IDFSDPIAIGPIATPEEYIKYRYEAM-------- 228

Query: 242 RGRPRTVEREVHERVIRRIVEKIER--NKKDIFDYEARELDDAEVAIVTTGIVARSALRA 299
               + +ER   + VI  I+ + ER   +K     E  + +DA+   VT G  +     A
Sbjct: 229 ----KAMERA--KGVIEEIMGEYERISGRKQHGLVECYKCEDAKYVFVTMGAWSGDGKAA 282

Query: 300 IKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYV 338
           +  LR+ G+K GLLKI    PF  E +E+    ++ + V
Sbjct: 283 VDRLRDSGVKTGLLKIRVFRPFPKEKVEEYLRSMKGVVV 321


>pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-)
           alpha chain PAB1472 [similarity] - Pyrococcus abyssi
           (strain Orsay) >gi|5458784|emb|CAB50271.1| (AJ248287)
           KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (EC 1.-.-.-)
           (VOR) [Pyrococcus abyssi]
           Length = 395
           
 Score =  101 bits (249), Expect = 2e-20
 Identities = 100/336 (29%), Positives = 152/336 (44%), Gaps = 27/336 (8%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV--IQMEDEIASIAAI 70
           + G+ A A A + A  +  A YPITP + I E +A ++   +  +  I +E E +++AA 
Sbjct: 11  VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 70

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           IGAS  GA+  TATS  G +LM E + +A     PIV+VDV R       P      D  
Sbjct: 71  IGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR----AMAPPWSVWDDQT 126

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188
            S+  +  D   +       QE +D  + AF +AE    P +++  A +  H  E V  I
Sbjct: 127 DSL--SQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184

Query: 189 PEPDEIEIVNRKLPQNEEEAKL-PFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRP-R 246
           P+    E+V+  LP  +    L  F +P        P     +R Y     H+E  +  +
Sbjct: 185 PQ----ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFR-YKLARAHEEAKKVIK 239

Query: 247 TVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELREL 306
            V RE  ER  R   E IE+            +DDA+   +  G +  +   A++ LR+ 
Sbjct: 240 DVGREFGERFGRDYSEMIEK----------AYIDDADFVFMGMGSLMGTVKEAVELLRKQ 289

Query: 307 GIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342
           G K G  K+    PF  E + +IA  V+ I V + N
Sbjct: 290 GYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325


>emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin oxidoreductase
           alpha-2 chain [Thermoplasma acidophilum]
           Length = 402
           
 Score = 98.3 bits (241), Expect = 1e-19
 Identities = 103/374 (27%), Positives = 168/374 (44%), Gaps = 48/374 (12%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAIIG 72
           G++A+A  A LA  +F + YPITP + I E +A  +    +D   +++E E +++AA+  
Sbjct: 23  GNDAVAYGAKLARVKFISAYPITPQTTIVEKLASMIANDELDAKYVEVESEHSALAAVFA 82

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           +   G ++ TATS  G   M E + +      PIV+  V R   + G P          +
Sbjct: 83  SELTGVRSYTATSSHGLLYMHEMLHWVAGQRLPIVMSVVNR---AIGPPW---------N 130

Query: 133 IWGTHGDHS-------LIVLSPSTVQEAFDFTIRAFNLAEK--YRTPVILLSDAEV-GHM 182
           IW    D         + V S S  QEA D  I  + +AE      P++ + DA +  H 
Sbjct: 131 IWADQSDTINQRDTGWMQVYSESN-QEAMDTIIMGYKIAENSGVMLPLMSMEDAFILSHT 189

Query: 183 RERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDP--HGDFVPPMPIFGRGYRTYVTGLTHD 240
            E V + + D   +VN  LP  + + ++   +P  +G +  P   F    +  +  + + 
Sbjct: 190 SEPVTMRDQD---LVNEYLPDLDLKFRIDPENPMGYGSYDTPDGSFMEFKKDMIDSMNN- 245

Query: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300
                    R+V +   ++  E  E N   +   E   +DDA+ AI+  G VA +A   I
Sbjct: 246 --------ARKVIKEETQKFNEMFETNYGALI--ERYRMDDADYAIIAMGTVASTARFVI 295

Query: 301 KELRELGIKAGLLKINTIWPFDF-ELIE-----KIAGKVERIYVPEMNLGQLYHLVREGA 354
             LRE G+  GL++I    PF + E++E     K AG ++R  V     G  Y  V  G 
Sbjct: 296 DRLRENGLNIGLIRIRYFRPFPYDEILEDLKNVKSAGVIDR-SVSFGLAGVTYSEVISGL 354

Query: 355 NGKAEVKLISKIGG 368
            G+  + + S I G
Sbjct: 355 YGRINIPVSSFIVG 368


>sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
           OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
           OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280154|pir||T45085
           2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-)
           alpha chain vorA - Pyrococcus furiosus
           >gi|1197360|emb|CAA59502.1| (X85250) 2-ketovalerate
           ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus]
           Length = 394
           
 Score = 96.7 bits (237), Expect = 4e-19
 Identities = 95/335 (28%), Positives = 152/335 (45%), Gaps = 25/335 (7%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV--IQMEDEIASIAAI 70
           + G+ A A AA+ A  +  A YPITP + I E +A ++   +  +  I +E E +++AA 
Sbjct: 10  VSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 69

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           IGAS  GA+  TATS  G +LM E + +A     PIV+VDV R       P      D  
Sbjct: 70  IGASATGARTFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR----AMAPPWSVWDDQT 125

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188
            S+  +  D   +       QE +D  + A+ +AE    P +++  A +  H  + V  I
Sbjct: 126 DSL--SQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNVPAMVVESAFILSHTYDVVEMI 183

Query: 189 PEPDEIEIVNRKLPQNEEEAKLP-FGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRT 247
           P+    E+V+  LP  +    L  F +P        P     +R Y     H+E      
Sbjct: 184 PQ----ELVDEFLPPRKPLYSLANFDEPIAVGALATPNDYYEFR-YKLAKAHEE------ 232

Query: 248 VEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELG 307
             ++V + V +   E+  R+   +   E   +DDA+   +  G +  +   A+  LR+ G
Sbjct: 233 -AKKVIKEVGKEFGERFGRDYSQMI--ETGYIDDADFVFMGMGSLMGTVKEAVDLLRKEG 289

Query: 308 IKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342
            K G  K+    PF  E + +IA  V+ I V + N
Sbjct: 290 YKVGYAKVRWFRPFPKEELVEIAESVKGIAVLDRN 324


>pir||A71114 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3257088|dbj|BAA29771.1| (AP000003) 397aa
           long hypothetical ferredoxin oxidoreductase alpha
           subunit [Pyrococcus horikoshii]
           Length = 397
           
 Score = 94.8 bits (232), Expect = 2e-18
 Identities = 96/336 (28%), Positives = 153/336 (44%), Gaps = 27/336 (8%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV--IQMEDEIASIAAI 70
           + G+ A A AA+ A  +  A YPITP + I E +A ++   +  +  I +E E +++AA 
Sbjct: 13  VSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 72

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           IGAS  GA+  TATS  G +LM E + +A  +  PIV+V+V R       P      D  
Sbjct: 73  IGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNR----AMAPPWSVWDDQT 128

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188
            S+  +  D   +       QE +D  + A+ +AE    P +++  A +  H  E V  I
Sbjct: 129 DSL--SQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFILSHTYEVVNMI 186

Query: 189 PEPDEIEIVNRKLPQNEEEAKL-PFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRP-R 246
           P+    E+V+  LP  +    L  F +P        P     +R Y     H+E  +  +
Sbjct: 187 PQ----ELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFR-YKIAKAHEEAKKVIK 241

Query: 247 TVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELREL 306
           +V +E  ER  R   + IE             ++DA+   +  G +  +   A+  LR+ 
Sbjct: 242 SVGKEFGERFGRDYSKMIETG----------YIEDADFVFMGMGSLMGTVKEAVDLLRKE 291

Query: 307 GIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342
           G K G  K+    PF  E + +IA  V+ I V + N
Sbjct: 292 GYKVGYAKVRWFRPFPKEELLEIAESVKGIAVLDRN 327


>sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
           OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
           OXIDOREDUCTASE ALPHA SUBUNIT)
           Length = 394
           
 Score = 94.8 bits (232), Expect = 2e-18
 Identities = 96/336 (28%), Positives = 153/336 (44%), Gaps = 27/336 (8%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV--IQMEDEIASIAAI 70
           + G+ A A AA+ A  +  A YPITP + I E +A ++   +  +  I +E E +++AA 
Sbjct: 10  VSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 69

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           IGAS  GA+  TATS  G +LM E + +A  +  PIV+V+V R       P      D  
Sbjct: 70  IGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNR----AMAPPWSVWDDQT 125

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188
            S+  +  D   +       QE +D  + A+ +AE    P +++  A +  H  E V  I
Sbjct: 126 DSL--SQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFILSHTYEVVNMI 183

Query: 189 PEPDEIEIVNRKLPQNEEEAKL-PFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRP-R 246
           P+    E+V+  LP  +    L  F +P        P     +R Y     H+E  +  +
Sbjct: 184 PQ----ELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFR-YKIAKAHEEAKKVIK 238

Query: 247 TVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELREL 306
           +V +E  ER  R   + IE             ++DA+   +  G +  +   A+  LR+ 
Sbjct: 239 SVGKEFGERFGRDYSKMIETG----------YIEDADFVFMGMGSLMGTVKEAVDLLRKE 288

Query: 307 GIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342
           G K G  K+    PF  E + +IA  V+ I V + N
Sbjct: 289 GYKVGYAKVRWFRPFPKEELLEIAESVKGIAVLDRN 324


>gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alpha subunit [Methanococcus
           maripaludis]
           Length = 387
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 103/383 (26%), Positives = 159/383 (40%), Gaps = 42/383 (10%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70
           I G  A A AA LA     A YPITP +   E +A ++    ++   I++E E ++++A 
Sbjct: 7   ITGTSAAAEAAKLADVDVIAAYPITPQTTCVEKLADFVANGELNAEYIKVESEHSAMSAS 66

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           IGAS AGA+A TATS  G +LM E +  A     P+V+++  R   +        Q  + 
Sbjct: 67  IGASAAGARAFTATSSQGLALMHEVLFAAAGMRVPVVMMNANRALSAPINIWNDQQDSLS 126

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLA--EKYRTPVILLSDAEV-GHMRERVY 187
           Q       D   I L     QE  D  I+AF +A  EK   PV++  D  +  H  E V 
Sbjct: 127 QR------DTGWIQLYAEDNQEVLDLVIQAFKIAEDEKVLLPVMVNLDGFILTHTVEPVT 180

Query: 188 IPEPDEI-------EIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240
           +P+ + +       E  +  L   +   +   GDP+             Y          
Sbjct: 181 LPKQENVLDFIGTYEPKHAYLDPKKPMTQGALGDPN-------------YYMETRYAIET 227

Query: 241 ERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAI 300
                + V  +VH+       EK  R   +    E+  L+ AE  IV  G +  +    I
Sbjct: 228 AMENAKKVIADVHD----AFAEKFNRAYGNGL-IESYNLEKAENVIVAMGSICGTIKDMI 282

Query: 301 KELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE------MNLGQLYHLVREGA 354
              ++ G++ GLLKI    P   E+I+      + + + +      MN G +Y  V    
Sbjct: 283 DLKKKEGVEIGLLKIRCYRPLPIEMIKDALKNAKNVAILDKSISLGMNKGAIYADVASHL 342

Query: 355 NGKAEVKLISKIGGEVHTPMEIV 377
             K  V  I  +GG   TP +I+
Sbjct: 343 KDKKTVNYIVGLGGRDITPEDIL 365


>emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin oxidoreductase
           [Thermotoga maritima]
           >gi|4980501|gb|AAD35111.1|AE001690_5 (AE001690) pyruvate
           ferredoxin oxidoreductase, alpha subunit [Thermotoga
           maritima]
           Length = 394
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 103/328 (31%), Positives = 146/328 (44%), Gaps = 36/328 (10%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV----IQMEDEIASIA 68
           + G EA+A A         A YPITP + I E  A ++   DGVV    I +E E ++++
Sbjct: 12  VTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFV--ADGVVRTEMIPVESEHSAMS 69

Query: 69  AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQR--GGPSTGQPTLPSQ 126
           A++GA+ AGA+AMTATS  G +LM E +  A     PIV+  V R   GP          
Sbjct: 70  AVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPIN---IHCDH 126

Query: 127 GDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLA--EKYRTPVILLSDAEV-GHMR 183
            D M        D   I L   T QEA+DFTI A  LA  E  R PV++  D  +  H  
Sbjct: 127 SDAM-----AERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGV 181

Query: 184 ERVYIPEPDEIEIVNRKLPQNEEEAKLPFGD-PHGDFVPPMPIFGRGYRTYVTGLTHDER 242
           E V    PDE+     K    E +   P  D  H     P+ ++   +          E 
Sbjct: 182 EPVEF-YPDELV----KKFVGELKPMYPLLDTEHPVTWGPLDLYDYYF----------EH 226

Query: 243 GRPRTVEREVHERVIRRIVEKIERN-KKDIFDYEARELDDAEVAIVTTGIVARSALRAIK 301
            R +    E  ++V   I ++ E    +  +  E   ++DAE  +V  G    +    + 
Sbjct: 227 KRQQIEAMENVKKVFPEIAKEFEETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVD 286

Query: 302 ELRELGIKAGLLKINTIWPFDFELIEKI 329
           ELRE G K G LKI    PF  E ++++
Sbjct: 287 ELREEGYKVGSLKIWMFRPFPKEQLQEL 314


>sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|7449946|pir||C72427 pyruvate synthase (EC
           1.2.7.1) alpha chain - Thermotoga maritima (strain MSB8)
           Length = 392
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 103/328 (31%), Positives = 146/328 (44%), Gaps = 36/328 (10%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV----IQMEDEIASIA 68
           + G EA+A A         A YPITP + I E  A ++   DGVV    I +E E ++++
Sbjct: 10  VTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFV--ADGVVRTEMIPVESEHSAMS 67

Query: 69  AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQR--GGPSTGQPTLPSQ 126
           A++GA+ AGA+AMTATS  G +LM E +  A     PIV+  V R   GP          
Sbjct: 68  AVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPIN---IHCDH 124

Query: 127 GDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLA--EKYRTPVILLSDAEV-GHMR 183
            D M        D   I L   T QEA+DFTI A  LA  E  R PV++  D  +  H  
Sbjct: 125 SDAM-----AERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGV 179

Query: 184 ERVYIPEPDEIEIVNRKLPQNEEEAKLPFGD-PHGDFVPPMPIFGRGYRTYVTGLTHDER 242
           E V    PDE+     K    E +   P  D  H     P+ ++   +          E 
Sbjct: 180 EPVEF-YPDELV----KKFVGELKPMYPLLDTEHPVTWGPLDLYDYYF----------EH 224

Query: 243 GRPRTVEREVHERVIRRIVEKIERN-KKDIFDYEARELDDAEVAIVTTGIVARSALRAIK 301
            R +    E  ++V   I ++ E    +  +  E   ++DAE  +V  G    +    + 
Sbjct: 225 KRQQIEAMENVKKVFPEIAKEFEETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVD 284

Query: 302 ELRELGIKAGLLKINTIWPFDFELIEKI 329
           ELRE G K G LKI    PF  E ++++
Sbjct: 285 ELREEGYKVGSLKIWMFRPFPKEQLQEL 312


>pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit - Pyrococcus
           horikoshii >gi|3257092|dbj|BAA29775.1| (AP000003) 398aa
           long hypothetical ferredoxin oxidoreductase alpha-2
           subunit [Pyrococcus horikoshii]
           Length = 398
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 97/327 (29%), Positives = 147/327 (44%), Gaps = 24/327 (7%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70
           ++ +EA A AA LA  +  A +PITP++ + E ++ ++    +D   I++E E ++I+A+
Sbjct: 10  MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAV 69

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           +GAS AG +  TAT+  G +LM E +  A     PIV+     G  S   P +    D  
Sbjct: 70  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMA---IGNRSLSAP-INIWNDWQ 125

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRERVY 187
            SI  +  D   I       QEA D  + A+ +AE  R   P ++  DA +  H  E V 
Sbjct: 126 DSI--SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 183

Query: 188 IPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRT 247
           IP+    E+V+  L   E E K  + DP          F   Y      L  D   + R 
Sbjct: 184 IPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYME-AKYLVWDAMEKARK 237

Query: 248 VEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELG 307
           V  E      +R   K ++        E  + DDAE+  VT G +A +    + + RE G
Sbjct: 238 VIDEAFAEFEKRFGRKYQK-------IEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEG 290

Query: 308 IKAGLLKINTIWPFDFELIEKIAGKVE 334
            K G  K+    PF  E I  +A K +
Sbjct: 291 YKVGAAKMTVYRPFPVEEIRALAKKAK 317


>sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT)
           Length = 395
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 97/327 (29%), Positives = 147/327 (44%), Gaps = 24/327 (7%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70
           ++ +EA A AA LA  +  A +PITP++ + E ++ ++    +D   I++E E ++I+A+
Sbjct: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAV 66

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           +GAS AG +  TAT+  G +LM E +  A     PIV+     G  S   P +    D  
Sbjct: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMA---IGNRSLSAP-INIWNDWQ 122

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRERVY 187
            SI  +  D   I       QEA D  + A+ +AE  R   P ++  DA +  H  E V 
Sbjct: 123 DSI--SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180

Query: 188 IPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRT 247
           IP+    E+V+  L   E E K  + DP          F   Y      L  D   + R 
Sbjct: 181 IPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYME-AKYLVWDAMEKARK 234

Query: 248 VEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELG 307
           V  E      +R   K ++        E  + DDAE+  VT G +A +    + + RE G
Sbjct: 235 VIDEAFAEFEKRFGRKYQK-------IEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEG 287

Query: 308 IKAGLLKINTIWPFDFELIEKIAGKVE 334
            K G  K+    PF  E I  +A K +
Sbjct: 288 YKVGAAKMTVYRPFPVEEIRALAKKAK 314


>pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicobacter pylori
           (strain 26695) >gi|2314261|gb|AAD08154.1| (AE000617)
           pyruvate ferredoxin oxidoreductase, alpha subunit
           [Helicobacter pylori 26695]
           Length = 407
           
 Score = 92.4 bits (226), Expect = 8e-18
 Identities = 92/331 (27%), Positives = 149/331 (44%), Gaps = 56/331 (16%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAIIG 72
           G+ A + A   A     A YPITP++ I +    +     VDG  + +E E A+++A +G
Sbjct: 15  GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVG 74

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A+ AG +  TATS  G +LM E +  A     PIV+  V R                + +
Sbjct: 75  AAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRA---------------LAA 119

Query: 133 IWGTHGDHSLIVLSPST---------VQEAFDFTIRAFNLAE--KYRTPVILLSDAEV-G 180
               HGDHS + LS  +          QEA+DFT+ AF +AE  K R P I+  D  +  
Sbjct: 120 PLNIHGDHSDMYLSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCS 179

Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240
           H  + V    P    +  + + + + +  L       DF  P+      Y        H 
Sbjct: 180 HTVQNV---RPLSDAVAYQFVGEYQTKHSLL------DFDKPV-----SYGAQAEEEWHY 225

Query: 241 ERGRPRTVEREVHERVI--RRIVEKIERNKKDIFDYEAR-----ELDDAEVAIVTTGIVA 293
           E       + ++H  ++    ++E++  +   +   +       +L+DAE+AI   G   
Sbjct: 226 EH------KAQLHHAIMSASSVIEEVFNDFAKLTGRQYHLTKTFQLEDAEIAIFALGTTY 279

Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFE 324
            SA+ A KE+R+ GIKAG+  I+++ PF +E
Sbjct: 280 ESAIVAAKEMRKKGIKAGVATIHSLRPFPYE 310


>pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter pylori  (strain
           J99) >gi|4155626|gb|AAD06616.1| (AE001531) Pyruvate
           ferrodoxin oxidoreductase [Helicobacter pylori J99]
           Length = 407
           
 Score = 92.4 bits (226), Expect = 8e-18
 Identities = 92/331 (27%), Positives = 149/331 (44%), Gaps = 56/331 (16%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAIIG 72
           G+ A + A   A     A YPITP++ I +    +     VDG  + +E E A+++A +G
Sbjct: 15  GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVG 74

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A+ AG +  TATS  G +LM E +  A     PIV+  V R                + +
Sbjct: 75  AAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRA---------------LAA 119

Query: 133 IWGTHGDHSLIVLSPST---------VQEAFDFTIRAFNLAE--KYRTPVILLSDAEV-G 180
               HGDHS + LS  +          QEA+DFT+ AF +AE  K R P I+  D  +  
Sbjct: 120 PLNIHGDHSDMYLSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCS 179

Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240
           H  + V    P    +  + + + + +  L       DF  P+      Y        H 
Sbjct: 180 HTVQNV---RPLSDAVAYQFVGEYQTKHSLL------DFDKPV-----SYGAQAEEEWHY 225

Query: 241 ERGRPRTVEREVHERVI--RRIVEKIERNKKDIFDYEAR-----ELDDAEVAIVTTGIVA 293
           E       + ++H  ++    ++E++  +   +   +       +L+DAE+AI   G   
Sbjct: 226 EH------KAQLHHAIMSASSVIEEVFNDFAKLTGRQYHLTKTFQLEDAEIAIFALGTTY 279

Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFE 324
            SA+ A KE+R+ GIKAG+  I+++ PF +E
Sbjct: 280 ESAIVAAKEMRKKGIKAGVATIHSLRPFPYE 310


>gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alpha subunit
           [Helicobacter pylori]
           Length = 396
           
 Score = 92.1 bits (225), Expect = 1e-17
 Identities = 91/331 (27%), Positives = 149/331 (44%), Gaps = 56/331 (16%)

Query: 15  GDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAIIG 72
           G+ A + A   A     A YPITP++ I +    +     +DG  + +E E A+++A +G
Sbjct: 15  GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGEFVLVESEHAAMSACVG 74

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A+ AG +  TATS  G +LM E +  A     PIV+  V R                + +
Sbjct: 75  AAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRA---------------LAA 119

Query: 133 IWGTHGDHSLIVLSPST---------VQEAFDFTIRAFNLAE--KYRTPVILLSDAEV-G 180
               HGDHS + LS  +          QEA+DFT+ AF +AE  K R P I+  D  +  
Sbjct: 120 PLNIHGDHSDMYLSRDSGWISLCTCNPQEAYDFTLMAFKIAEHQKVRVPTIVNQDGFLCS 179

Query: 181 HMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHD 240
           H  + V    P    +  + + + + +  L       DF  P+      Y        H 
Sbjct: 180 HTVQNV---RPLSDAVAYQFVGEYQTKHSLL------DFDKPV-----SYGAQAEEEWHY 225

Query: 241 ERGRPRTVEREVHERVI--RRIVEKIERNKKDIFDYEAR-----ELDDAEVAIVTTGIVA 293
           E       + ++H  ++    ++E++  +   +   +       +L+DAE+AI   G   
Sbjct: 226 EH------KAQLHHAIMSASSVIEEVFNDFAKLTGRQYHLTKTFQLEDAEIAIFALGTTY 279

Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFE 324
            SA+ A KE+R+ GIKAG+  I+++ PF +E
Sbjct: 280 ESAIVAAKEMRKKGIKAGVATIHSLRPFPYE 310


>pir||E75038 indolepyruvate ferredoxin oxidoreductase, chain alpha  (iora-1)
           PAB0855 - Pyrococcus abyssi (strain Orsay)
           >gi|5458715|emb|CAB50202.1| (AJ248287) indolepyruvate
           ferredoxin oxidoreductase, subunit alpha (iorA-1)
           [Pyrococcus abyssi]
           Length = 648
           
 Score = 92.1 bits (225), Expect = 1e-17
 Identities = 91/336 (27%), Positives = 143/336 (42%), Gaps = 45/336 (13%)

Query: 8   GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASI 67
           G+   + G++AI R A+      YA YP TP+SEI + MA         +    +E  + 
Sbjct: 14  GERVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAAVASRAGVYMEYSTNEKVAF 73

Query: 68  AAIIGASWAGAKAMTATSGPGFSLMQEN---IGYAVMTETPIVVVDVQRGGPSTGQPTLP 124
              + ASWAG +AMTA    G ++  ++   + Y  +    +VVV           P++ 
Sbjct: 74  ETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGVNGGLVVVV--------ADDPSMW 125

Query: 125 SQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRE 184
           S  +  Q         ++ VL PS+VQEA D    AF ++EKY   VIL +     HMR 
Sbjct: 126 SSQN-EQDTRAIAKFANIPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRG 184

Query: 185 RVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGR 244
            V + E          LPQ  +E K  FGD           F +    YV          
Sbjct: 185 DVVLGE----------LPQEIKEGKRKFGD-----------FKKNPERYVD--------- 214

Query: 245 PRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELR 304
               +R  H+ ++  I +  E      F++     +DA+V I+  G+       A+  L 
Sbjct: 215 IPAFQRPKHKWLLETIEKFREEFNNSPFNW-IEGPEDAKVGIIAPGLSYAYVKEALAWLG 273

Query: 305 ELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340
              +K  +LK+ T +P  + L+EK    +ER+ + E
Sbjct: 274 VDNVK--VLKLGTPFPVPYGLLEKFFQGLERVLIVE 307


>sp|O58495|IORA_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE
           FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           >gi|7450338|pir||F71124 probable indolepyruvate
           ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3257173|dbj|BAA29856.1| (AP000003) 648aa
           long hypothetical indolepyruvate ferredoxin
           oxidoreductase alpha subunit [Pyrococcus horikoshii]
           Length = 648
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 94/338 (27%), Positives = 146/338 (42%), Gaps = 49/338 (14%)

Query: 8   GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASI 67
           G+   + G++AI R A+      YA YP TP+SEI + MA+        +    +E  + 
Sbjct: 14  GEKVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAMVAKKAGVYMEYSTNEKVAF 73

Query: 68  AAIIGASWAGAKAMTATSGPGFSLMQEN---IGYAVMTETPIVVVDVQRGGPSTGQPTLP 124
              + ASWAG +AMTA    G ++  ++   + Y  +    IVVV           P++ 
Sbjct: 74  ETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGINGGLIVVV--------ADDPSMW 125

Query: 125 SQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRE 184
           S  +  Q         ++ VL PS+VQEA D    AF ++EKY   VIL +     HMR 
Sbjct: 126 SSQN-EQDTRAIAKFANIPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRG 184

Query: 185 RVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGR 244
            V + E          LPQ  +E K  FG+           F +    YV          
Sbjct: 185 DVVLGE----------LPQEIKEGKRKFGN-----------FKKNPEKYVD--------- 214

Query: 245 PRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKE-L 303
               +R  H  ++  I +  E      F++     +DA+V I+  G+    +   +KE L
Sbjct: 215 IPAFQRPKHPWLLETIEKFREEFNTSPFNW-IEGPEDAKVGIIAPGL----SYAYVKEAL 269

Query: 304 RELGI-KAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340
             LGI    +LK+ T +P  + L+EK    +ER+ + E
Sbjct: 270 AWLGIDNVKILKLGTPFPVPYGLLEKFFNGLERVLIVE 307


>gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (porA)
           [Archaeoglobus fulgidus] >gi|7449947|pir||D69462
           pyruvate synthase (EC 1.2.7.1) alpha chain -
           Archaeoglobus fulgidus >gi|2648853|gb|AAB89548.1|
           (AE000986) pyruvate ferredoxin oxidoreductase, subunit
           alpha (porA) [Archaeoglobus fulgidus]
           Length = 391
           
 Score = 90.1 bits (220), Expect = 4e-17
 Identities = 103/381 (27%), Positives = 156/381 (40%), Gaps = 51/381 (13%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP---LVDGVVIQMEDEIASIAA 69
           ++G  ++A +  L        YPITP +EI E +A       L D   I  E E  + + 
Sbjct: 5   VRGFYSVAYSVKLCKPNVICAYPITPQTEIVENLAAMYANGELGDAEYITAESEFGAASM 64

Query: 70  IIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDI 129
           ++GAS AGA+  TAT   G  LM E +  A     PIV+V+  R   +   P        
Sbjct: 65  LVGASAAGARVFTATCSQGLILMSEVLFNAAGMRLPIVLVNTNR---ALSAPL------- 114

Query: 130 MQSIWGTHGDH------SLIVLSPSTVQEAFDFTIRAFNLAE--KYRTPVILLSDAEVGH 181
             SIW  H D        ++ +     QEA D   +A+ +AE  K   P ++  D   G+
Sbjct: 115 --SIWNDHQDSMAMRDAGIMQVYVENNQEAHDMIPQAYKVAENRKVLLPFMICMD---GY 169

Query: 182 MRERVYIP-EPDEIEIVNRKLPQNEEEAKLPFGDP--HGDFVPPMPIFGRGYRTYVTGLT 238
                Y P +  E E V+  LP  E  A +    P   G + PP       Y  +   + 
Sbjct: 170 KLTHAYEPVDLLEQETVDSFLPPYEPAAYMTTKKPLAFGCYAPP-----HVYMEFRVAM- 223

Query: 239 HDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALR 298
                R R +  +V +       E  E   +D   +   +  D+++ +V  G V     +
Sbjct: 224 QQAMERARKIMLDVFK-------EWGELTGRDWGGHITVDFPDSKIFVVAMGSVVGLLRK 276

Query: 299 AIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNLGQLYHLVREGANGKA 358
            ++ELR  G+  GL+KI T  PF  E + +     E++ V       L   V  G  G  
Sbjct: 277 VVEELRGEGLSVGLIKIRTFRPFPVEELREALKDAEKVIV-------LDRSVSFGYEGPV 329

Query: 359 EVKLISKIGGEVHTPMEIVDF 379
            ++L S I G  H+  EI  F
Sbjct: 330 SIELKSAIYG--HSSAEIYSF 348


>pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 - Pyrococcus
           abyssi (strain Orsay) >gi|5458781|emb|CAB50268.1|
           (AJ248287) PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1)
           (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) [Pyrococcus
           abyssi]
           Length = 395
           
 Score = 89.3 bits (218), Expect = 7e-17
 Identities = 94/331 (28%), Positives = 148/331 (44%), Gaps = 32/331 (9%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70
           ++ +EA A AA LA  +  A +PITP++ + E ++ ++    +D   I++E E ++I+A+
Sbjct: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           +GAS AG +  TAT+  G +LM E +  A     PIV+        + G   L +  +I 
Sbjct: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM--------AIGNRALSAPINIW 118

Query: 131 QSIWGT--HGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRER 185
                T    D   I       QEA D  + A+ +AE  R   P ++  DA +  H  E 
Sbjct: 119 NDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEP 178

Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGY--RTYVTGLTHDERG 243
           V IP+    E+V+  L   E E K  + DP          F   Y    Y+     +   
Sbjct: 179 VEIPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMEN-- 231

Query: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303
                 R+V +       +K  R  + I +Y     DDAE+  VT G +A +    + + 
Sbjct: 232 -----ARKVIDEAFAEFEKKFGRKYQKIEEYRT---DDAEIIFVTMGSLAGTLKDWVDKK 283

Query: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVE 334
           RE G K G  K+    PF  E I ++A K +
Sbjct: 284 REEGYKVGAAKMTVYRPFPVEEIRELAKKTK 314


>sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|11280155|pir||T45088 pyruvate synthase (EC
           1.2.7.1) alpha-2 chain [imported] - Pyrococcus furiosus
           >gi|1197363|emb|CAA59505.1| (X85250) pyruvate ferredoxin
           oxidoreductase alpha-2 [Pyrococcus furiosus]
           Length = 396
           
 Score = 87.4 bits (213), Expect = 3e-16
 Identities = 96/339 (28%), Positives = 153/339 (44%), Gaps = 30/339 (8%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70
           ++ +EA A AA LA  +  A +PITP++ I E ++ ++    +D   I++E E ++I+A 
Sbjct: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEHSAISAC 66

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
           +GA+ AG +  TAT+  G +LM E +  A     PIV+        + G   L +  +I 
Sbjct: 67  VGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVM--------AIGNRALSAPINIW 118

Query: 131 QSIWGT--HGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRER 185
                T    D   +       QEA D  + A+ +AE  R   P ++  DA +  H  E 
Sbjct: 119 NDWQDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEP 178

Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGY-RTYVTGLTHDERGR 244
           V IP+    E+V+  L   E E K  + DP          F   Y  +  T     ER  
Sbjct: 179 VEIPDQ---EVVDEFL--GEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERA- 232

Query: 245 PRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELR 304
                ++V +       +K  R  + I +Y+    +DA++  VT G +A +    I + R
Sbjct: 233 -----KKVIDEAFAEFEKKFGRKYQKIEEYKT---EDADIIFVTMGSLAGTLNEWIDKKR 284

Query: 305 ELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL 343
           E G K G  KI    PF  E I ++A K + +   E N+
Sbjct: 285 EEGYKVGAAKITVYRPFPVEEIRELAKKAKVLAFLEKNI 323


>pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus
           >gi|2983615|gb|AAC07184.1| (AE000726) ferredoxin
           oxidoreductase alpha subunit [Aquifex aeolicus]
           Length = 389
           
 Score = 85.8 bits (209), Expect = 8e-16
 Identities = 100/390 (25%), Positives = 152/390 (38%), Gaps = 64/390 (16%)

Query: 12  FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMA-LYMPLVDGVVIQMEDEIASIAAI 70
           FI G +A A A   A       YPITP SE    +  LY         + E+E  +++AI
Sbjct: 22  FITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRAEEEYGAMSAI 81

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQR--GGPSTGQPTLPSQGD 128
            GA   GA+A TATSGPG     E I        P V+  + R    P + QP       
Sbjct: 82  AGAVRGGARAFTATSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISY 141

Query: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEK---YRTPVILLSDAEVGHMRER 185
           ++ S         L+VL     Q+ FDFT+  F ++EK   Y   V+      V H +  
Sbjct: 142 LLNS--------GLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193

Query: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPP-------------MPIFGRGYRT 232
           V +P                E+ KLP  DP+   VPP              P+    + +
Sbjct: 194 VELP---------------PEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMS 238

Query: 233 YVTGLTHDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELD----DAEVAIVT 288
           Y+                 +H    + +     R  K I  Y    ++    DAEV +V 
Sbjct: 239 YL-----------------IHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVA 281

Query: 289 TGIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL-GQLY 347
           +G  A     A +     G+  GL+K+ ++ PF  + I +     + + VPE N+ G L 
Sbjct: 282 SGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLA 341

Query: 348 HLVREGANGKAEVKLISKIGGEVHTPMEIV 377
             V+        V    ++ G +  P+E++
Sbjct: 342 KEVKAAIPNSGIVVDGPRVYGGMTLPVELI 371


>gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
           alpha chain) (porA-like) [Sulfolobus solfataricus]
           Length = 415
           
 Score = 83.1 bits (202), Expect = 5e-15
 Identities = 96/398 (24%), Positives = 149/398 (37%), Gaps = 49/398 (12%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAI 70
           + G +A+A AA+ A     A YPI P +E+ + ++  +    +D   I  E E      +
Sbjct: 14  MNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFETV 73

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
             AS AGA+ +  +SG G+    E I        P+V +   R     G   +     +M
Sbjct: 74  KHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDALM 133

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE 190
                   D   +++   T QEAFD  + A+ +AE  R  + L    + G +     I  
Sbjct: 134 VR------DVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVR 187

Query: 191 PDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVER 250
               E+V   LP        P+        P  PI      T    +  D     R    
Sbjct: 188 LPPRELVKNFLP--------PYNRGKYLVHPDNPI------TVAPQVNEDWVMEIRRQHE 233

Query: 251 EVHERVIRRIVEKIERNKKDIFDY---------------EARELDDAEVAIVTTGIVARS 295
           E  ER    IVE  E  KK    Y               E   +DDAEV ++  G V++ 
Sbjct: 234 EAMERARSVIVEAYEEFKKVFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKP 293

Query: 296 ALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL--------GQLY 347
              AIK +R  G K G+L+I    PF  + + +       + V + +         G +Y
Sbjct: 294 MKVAIKNMRRQGYKVGMLRIRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIY 353

Query: 348 HLVREGANGKAE----VKLISKIGGEVHTPMEIVDFIR 381
           H VR       +    +  I  +GG   T  ++   I+
Sbjct: 354 HEVRSSLYDLDQRPRVMNFIGGLGGREITIQDVEKIIK 391


>pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolobus
           solfataricus >gi|1707735|emb|CAA69455.1| (Y08256)
           pyruvate-ferredoxin oxidoreductase alpha-2 [Sulfolobus
           solfataricus]
           Length = 415
           
 Score = 83.1 bits (202), Expect = 5e-15
 Identities = 96/398 (24%), Positives = 149/398 (37%), Gaps = 49/398 (12%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAI 70
           + G +A+A AA+ A     A YPI P +E+ + ++  +    +D   I  E E      +
Sbjct: 14  MNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFETV 73

Query: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
             AS AGA+ +  +SG G+    E I        P+V +   R     G   +     +M
Sbjct: 74  KHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDALM 133

Query: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPE 190
                   D   +++   T QEAFD  + A+ +AE  R  + L    + G +     I  
Sbjct: 134 VR------DVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVR 187

Query: 191 PDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVER 250
               E+V   LP        P+        P  PI      T    +  D     R    
Sbjct: 188 LPPRELVKNFLP--------PYNRGKYLVHPDNPI------TVAPQVNEDWVMEIRRQHE 233

Query: 251 EVHERVIRRIVEKIERNKKDIFDY---------------EARELDDAEVAIVTTGIVARS 295
           E  ER    IVE  E  KK    Y               E   +DDAEV ++  G V++ 
Sbjct: 234 EAMERARSVIVEAYEEFKKVFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKP 293

Query: 296 ALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL--------GQLY 347
              AIK +R  G K G+L+I    PF  + + +       + V + +         G +Y
Sbjct: 294 MKVAIKNMRRQGYKVGMLRIRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIY 353

Query: 348 HLVREGANGKAE----VKLISKIGGEVHTPMEIVDFIR 381
           H VR       +    +  I  +GG   T  ++   I+
Sbjct: 354 HEVRSSLYDLDQRPRVMNFIGGLGGREITIQDVEKIIK 391


>gb|AAK42250.1| Indolepyruvate ferredoxin oxidoreductase alpha subunit (iorA)
           [Sulfolobus solfataricus]
           Length = 612
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 88/328 (26%), Positives = 134/328 (40%), Gaps = 52/328 (15%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72
           I G+EAIA  A+ AG    AGYP TP++EI E +  +  +         +E  +     G
Sbjct: 11  ILGNEAIAFGALSAGVSVAAGYPGTPSTEIIETLMKFGKIY---AEWSTNEKVAFETAYG 67

Query: 73  ASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQS 132
           A+  GA A+T     G ++  + +  +  T     +V V    PS       SQ +    
Sbjct: 68  AAINGAFALTTMKHVGLNVAADPLISSSYTGVEGALVIVSADDPSMWS----SQNEQDNR 123

Query: 133 IWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYIPEPD 192
            +G H    + V+ P   Q A D TI AF L+ K + PVI  S   +GH+R  V +  P 
Sbjct: 124 YYGLHA--LIPVVEPYDPQSAHDLTIEAFKLSNKVKHPVIFRSTTRIGHIRGPVELKPPS 181

Query: 193 EIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTVEREV 252
                                       P M    +  + YV    +  R R   ++R  
Sbjct: 182 R---------------------------PVMGKVIKNPKRYVLVPENARRDRVEQLKR-- 212

Query: 253 HERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELRELGIKAGL 312
                 RI E++E    ++ D      +D+E  I+ +GI     + AIKEL    IKA +
Sbjct: 213 ----WERIEEEVE-GLNELID------NDSENLIIASGISFGYVIDAIKELE---IKANI 258

Query: 313 LKINTIWPFDFELIEKIAGKVERIYVPE 340
           L++ T  P    LI K     +R+ + E
Sbjct: 259 LRLTTPVPIPKRLILKAVSNSKRVLIVE 286


>gb|AAD28766.1| (AF132216) 2-oxoisovalerate oxidoreductase beta subunit
          [Prevotella albensis]
          Length = 104
          
 Score = 80.8 bits (196), Expect = 3e-14
 Identities = 43/88 (48%), Positives = 56/88 (62%), Gaps = 2/88 (2%)

Query: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMP--LVDGVVIQMEDEIASIAAI 70
          ++G+EAIA AAI  G   + GYPITP SEI E +AL  P      VV+Q E E+ASI  +
Sbjct: 8  MKGNEAIAHAAIRCGADGFFGYPITPQSEIIETLALLKPWETTGMVVLQAESEVASINML 67

Query: 71 IGASWAGAKAMTATSGPGFSLMQENIGY 98
           G + AG + +T +S PG +LMQE I Y
Sbjct: 68 YGGAGAGKRVLTTSSSPGVALMQEGIAY 95


>emb|CAC12141.1| (AL445066) indolepyruvate ferredoxin oxidoreductase, alpha subunit
           related protein [Thermoplasma acidophilum]
           Length = 605
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 88/343 (25%), Positives = 139/343 (39%), Gaps = 69/343 (20%)

Query: 9   KADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIA 68
           KA F+ G+EAIA AA+ AG    AGYP TP++EI E +  + P  D  V    +E  +  
Sbjct: 4   KAKFMIGNEAIAAAAVHAGVSVAAGYPGTPSTEIIENVRKFGP--DVYVEWSVNEKIAFE 61

Query: 69  AIIGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGD 128
              GA+ +G   + A    G ++  + +  +  T               TG   + S  D
Sbjct: 62  TAYGAAMSGGTGLVAVKHVGLNVASDPMFSSSYTGI-------------TGSLVIVSADD 108

Query: 129 IMQSIWGT--------HGDHSLI-VLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV 179
              S+W +        +G H+LI VL P  VQ A+D T++AF ++  +  PVIL +   +
Sbjct: 109 --SSMWSSQNEQDNRFYGLHALIPVLEPYDVQSAYDLTLKAFEVSRLFHHPVILRTTTRI 166

Query: 180 GHMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTH 239
           GH+R  V   +  E        P   +  K P                    TYV    +
Sbjct: 167 GHVRSNVIYEDHHE--------PLRGKVIKDP-------------------NTYVLAPEN 199

Query: 240 DERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRA 299
               R + +ER            +I      +  YE     D   +I+ TG ++ S L+ 
Sbjct: 200 ARSDRKKQLER----------WREISDYLSSLCSYE----PDGGDSIIITGGISYSYLK- 244

Query: 300 IKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342
            + L + GI   +L+++   P     I      + R+ V E N
Sbjct: 245 -EALEDAGIHTNVLRLDATVPIPESAILNHINGIRRVLVVEEN 286


>gi|11499084 indolepyruvate ferredoxin oxidoreductase, subunit alpha (iorA)
           [Archaeoglobus fulgidus]
           >gi|6685558|sp|O28783|IORA_ARCFU INDOLEPYRUVATE
           OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE
           FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           >gi|7450334|pir||H69435 indolepyruvate ferredoxin
           oxidoreductase, subunit alpha  (iorA) homolog -
           Archaeoglobus fulgidus >gi|2649079|gb|AAB89760.1|
           (AE001000) indolepyruvate ferredoxin oxidoreductase,
           subunit alpha (iorA) [Archaeoglobus fulgidus]
           Length = 623
           
 Score = 79.6 bits (193), Expect = 6e-14
 Identities = 91/347 (26%), Positives = 153/347 (43%), Gaps = 69/347 (19%)

Query: 8   GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV-IQME---DE 63
           G+  F+ G+EAIAR AI AG   +A YP TP+SEI + ++    L+ G +   ME   +E
Sbjct: 11  GEKVFLLGNEAIARGAIEAGIDVFAAYPGTPSSEIADTLSDACRLLRGKMDFYMEYSANE 70

Query: 64  IASIAAIIGASWAGAKAMTATSGPGFSLMQENI-GYAVMTETPIVVVDVQRGG---PSTG 119
             +    +GAS AG +AM      G ++  + +  +A +           RGG    +  
Sbjct: 71  KVAFEVAVGASLAGKRAMATMKHVGVNVAADPLFSFAYVG---------ARGGFVLVTAD 121

Query: 120 QPTLPSQGDIMQSIWGTHGDHS-LIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAE 178
            P++ S  +   + W  +G  + L V+ PS+VQEA D+    F+L+EK+  P+IL S   
Sbjct: 122 DPSMHSSQNEQDNRW--YGKAAKLPVVEPSSVQEAKDYAKLCFDLSEKFGLPMILRSYTR 179

Query: 179 VGHMRERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLT 238
           + H    V +           K+P+ E         P  D V P                
Sbjct: 180 LSHASGVVEL----------GKIPEKEFSRVEWERHPETDVVLP---------------A 214

Query: 239 HDERGRPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELD-----DAEVAIVTTGIVA 293
           H  + +P  +E+          +EKIER       + + E++     D +V I+  G+  
Sbjct: 215 HARKLKPILLEK----------LEKIERY------FNSSEMNWVDEGDGDVGIIACGL-- 256

Query: 294 RSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340
            S     + L  L +   +LK++++ P    LIE    +++++ V E
Sbjct: 257 -SYAYTKEALENLNLNLPVLKLSSMHPLPERLIENFVSQMKKVIVVE 302


>gb|AAD17273.1| (AF119361) ferredoxin oxidoreductase a-subunit [Frankia sp. EuIK1]
           Length = 671
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 54/172 (31%), Positives = 80/172 (46%), Gaps = 13/172 (7%)

Query: 30  FYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIAS------IAAIIGASWAGAKAMTA 83
           F   YPITPA+++   ++    L    V        S       AA   A WA      A
Sbjct: 258 FLGAYPITPATDVLHELS---KLTSHDVRHSRPRTRSRRSARRSAARSPACWASPSTSGA 314

Query: 84  TSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIMQSIWGTHGDHSLI 143
             G   + +       +       +V+VQRGGPSTG PT   Q D++Q+++G HG+  L 
Sbjct: 315 RHG---AQVPRRSACDLAGSCRWFIVNVQRGGPSTGLPTKTEQSDLLQALYGRHGEAPLP 371

Query: 144 VLSPSTVQEAFDFTIRAFNL-AEKYRTPVILLSDAEVGHMRERVYIPEPDEI 194
           VL+  +  + FD    A  + A   RTPVILLSD+ + +  E   +P  +E+
Sbjct: 372 VLAGESPADCFDAAFEAAQMRAGGRRTPVILLSDSYIANGSEPWKVPSVEEL 423


>pir||G75085 indolepyruvate ferredoxin oxidoreductase, chain alpha  (iora-2)
           PAB0718 - Pyrococcus abyssi (strain Orsay)
           >gi|5458500|emb|CAB49988.1| (AJ248286) indolepyruvate
           ferredoxin oxidoreductase, subunit alpha (iorA-2)
           [Pyrococcus abyssi]
           Length = 613
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 84/334 (25%), Positives = 138/334 (41%), Gaps = 60/334 (17%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72
           + G+EAIA  A+ +G  F  GYP TP++E+ E +A   P V        +E  ++    G
Sbjct: 5   LMGNEAIAYGALESGIAFATGYPGTPSTEVIETIARLKPEV--FAEWAPNEKVALEEAAG 62

Query: 73  ASWAGAKAMTATSGPGFSLMQE---NIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDI 129
            S+AG +++      G ++  +   ++ Y+ + E  +V++     GP T Q     Q D 
Sbjct: 63  VSYAGLRSLVTMKCVGLNVAADPLMSLAYSGV-EGGLVILVADDPGPHTSQ---TEQDD- 117

Query: 130 MQSIWGTHGDHSLI-VLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188
                  +G  +++ VL P   QEA D    A+ L+EKY+ PVI  +   V H    V +
Sbjct: 118 -----RYYGKIAILPVLEPYDPQEAHDLIKYAYELSEKYKVPVIFRTTTRVNHTTADVEV 172

Query: 189 PEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRPRTV 248
            E  E+   NRK                       P+F +    YV       R R + +
Sbjct: 173 GEFVEL---NRK-----------------------PVFKKDIERYVRASMEGNRRRHKWL 206

Query: 249 EREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSA-LRAIKE-LREL 306
                   IR+I E+      +  + E +            GI+   A    +KE L  +
Sbjct: 207 -----NETIRKIEEEFNSMPFNWVEGEGK-----------LGIIVEGAPYNYVKEILPSI 250

Query: 307 GIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340
           G    +LK++T  P   +L+      VE++ V E
Sbjct: 251 GEDFKILKLSTPHPLPRKLVLDFLKSVEKVIVIE 284


>pir||D71055 probable indolepyruvate ferredoxin oxidoreductase alpha subunit -
           Pyrococcus horikoshii >gi|3257555|dbj|BAA30238.1|
           (AP000005) 618aa long hypothetical indolepyruvate
           ferredoxin oxidoreductase alpha subunit [Pyrococcus
           horikoshii]
           Length = 618
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 57/182 (31%), Positives = 88/182 (48%), Gaps = 16/182 (8%)

Query: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASIAAIIG 72
           + G+EAIA  A+ AG  F  GYP TP++E+ E +A   P V        +E  ++    G
Sbjct: 10  LMGNEAIAYGALEAGVSFATGYPGTPSTEVIETIARLKPEV--FAEWAPNEKVALEEAAG 67

Query: 73  ASWAGAKAMTATSGPGFSLMQE---NIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDI 129
           AS+AG +++      G ++  +   ++ Y+ + E  +VV+     GP T Q     Q D 
Sbjct: 68  ASYAGIRSLVTMKCVGLNVAADPLMSLAYSGV-EGGLVVLVADDPGPHTSQ---TEQDD- 122

Query: 130 MQSIWGTHGDHSLI-VLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHMRERVYI 188
                  +G  SL+ VL P   QEA D    A+ L+EKY+ P+I  +   V H    V +
Sbjct: 123 -----RYYGKISLLPVLEPYDPQEAHDLIKYAYELSEKYKVPIIFRTTTRVNHTTADVEV 177

Query: 189 PE 190
            E
Sbjct: 178 GE 179


>sp|O07835|IORA_PYRKO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE
           FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           >gi|2209070|dbj|BAA20528.1| (D86221) indolepyruvate
           ferredoxin oxidoreductase alpha subunit [Pyrococcus sp.]
           Length = 647
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 83/343 (24%), Positives = 145/343 (42%), Gaps = 59/343 (17%)

Query: 8   GKADFIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVVIQMEDEIASI 67
           G+   + G+ AI R A+ A    +A YP TP+SE+              +    +E  + 
Sbjct: 14  GERVLLLGNHAIERGALEANIAVFAAYPGTPSSELTIRWQTVAKKAGVYMEYSTNEKVAF 73

Query: 68  AAIIGASWAGAKAMTATSGPGFSLMQEN----IGYAVMTETPIVVVDVQRGGPSTGQPTL 123
              + A+W+G +AMTA    G ++  ++    +G  V     I+V D          P++
Sbjct: 74  ETALAAAWSGLRAMTAMKHVGLNVAADSFLSSVGMGVEGGFVIMVAD---------DPSM 124

Query: 124 -PSQGDIMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEVGHM 182
             SQ +    ++    +  + VL PS+  EA + T  AF L+EK++  VIL +     H 
Sbjct: 125 WSSQNEQDTRVYAKFAN--VPVLEPSSPHEAKEMTKYAFELSEKFKHFVILRTTTRSSHA 182

Query: 183 RERVYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDER 242
           R  V + E          LP+  +  K  FG            F +    +V    H  +
Sbjct: 183 RGDVVLGE----------LPEEIKTGKRKFGK-----------FKKDPTRFVDVPAHARK 221

Query: 243 GRPRTVEREVHERVIRRIVEKIERNKKDI----FDY-EARELDDAEVAIVTTGIVARSAL 297
             P              I+EKIE+ ++++    F++ E +E  DA+V I+  G+      
Sbjct: 222 FHP-------------LILEKIEKIREELNNCPFNWIEGKE--DAKVGIIAPGLSYAYVK 266

Query: 298 RAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPE 340
            A+  L    +K  +LK+ T +P  + L+ K    +E++ + E
Sbjct: 267 EALAWLGVEDVK--ILKLGTPFPVPYGLLGKFFDGLEKVLIVE 307


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.140    0.407 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 146513081
Number of Sequences: 2977
Number of extensions: 6453748
Number of successful extensions: 15647
Number of sequences better than 1.0e-10: 68
Number of HSP's better than  0.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 15471
Number of HSP's gapped (non-prelim): 82
length of query: 385
length of database: 189,106,746
effective HSP length: 55
effective length of query: 330
effective length of database: 156,189,961
effective search space: 51542687130
effective search space used: 51542687130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)