BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0356 (TRUB) DE:PROBABLE TRNA PSEUDOURIDINE SYNTHASE B (EC
4.2.1.70) (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE)
(PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE).
(334 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75170 probable pseudouridylate synthase (EC 4.2.1.70) B PA... 677 0.0
sp|O59357|TRUB_PYRHO PROBABLE TRNA PSEUDOURIDINE SYNTHASE B (TRN... 645 0.0
sp|Q57612|TRUB_METJA PROBABLE TRNA PSEUDOURIDINE SYNTHASE B (TRN... 370 e-101
sp|O26140|TRUB_METTH PROBABLE TRNA PSEUDOURIDINE SYNTHASE B (TRN... 367 e-101
gi|11497854 centromere/microtubule-binding protein (cbf5) [Archa... 357 1e-97
sp|O43100|CBF5_EMENI CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5... 290 2e-77
pir||T47775 hypothetical protein F24I3.230 - Arabidopsis thalian... 287 2e-76
gb|AAF77119.1|AF234319_1 (AF234319) Cbf5p [Euglena gracilis] 286 2e-76
sp|O43102|CBF5_ASPFU CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5... 286 3e-76
sp|O43101|CBF5_CANAL CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5... 285 4e-76
emb|CAB85492.1| (AJ277097) putative kinetochore protein [Hordeum... 279 4e-74
emb|CAB86704.1| (AL163505) probable dyskerin [Leishmania major] 279 4e-74
sp|O14007|CBF5_SCHPO CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5... 277 1e-73
gb|AAG38982.1|AC082644_19 (AC082644) putative centromere/microtu... 277 1e-73
sp|O13473|CBF5_KLULA CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5... 277 2e-73
gi|6323204 major low affinity 55 kDa Centromere/microtubule bind... 275 4e-73
pir||F72696 probable nucleolar protein APE0990 - Aeropyrum perni... 273 1e-72
sp|O44081|NO60_DROME NUCLEOLAR PROTEIN AT BAND 60B >gi|2661227|g... 263 2e-69
gb|AAD19897.1| (AF097634) minifly protein [Drosophila melanogaster] 263 2e-69
gb|AAB94299.1| (U59151) Cbf5p homolog [Homo sapiens] 261 1e-68
gi|4503337 dyskeratosis congenita 1, dyskerin; Dyskerin [Homo sa... 261 1e-68
emb|CAB51168.1| (AJ010395) dyskerin [Homo sapiens] 261 1e-68
pir||A55163 nucleolar protein Nopp140, hepatic - rat >gi|1093316... 259 4e-68
sp|P40615|DKC1_RAT DYSKERIN (NUCLEOLAR PROTEIN NAP57) >gi|273932... 259 4e-68
emb|CAC04528.1| (AJ250973) DYSKERIN [Mus musculus] 253 2e-66
sp|O17919|NO50_CAEEL PUTATIVE NUCLEOLAR PROTEIN K01G5.5 >gi|7505... 251 7e-66
gb|AAG19966.1| (AE005078) tRNA-pseudouridine synthase; Sus [Halo... 247 1e-64
gb|AAK40720.1| tRNA pseudouridine synthase subunit B (truB) [Sul... 240 2e-62
emb|CAC12368.1| (AL445067) dyskerin (nucleolar protein Nap57) re... 210 3e-53
pir||A72325 tRNA-pseudouridine synthase (EC 5.4.99.-) TM0856 - T... 133 2e-30
pir||C82298 tRNA pseudouridine 55 synthase VC0645 [imported] - V... 123 2e-27
sp|P32732|TRUB_BACSU TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 119 5e-26
pir||E83052 tRNA pseudouridine 55 synthase PA4742 [imported] - P... 117 2e-25
dbj|BAB06129.1| (AP001515) tRNA pseudouridine 5S synthase [Bacil... 112 5e-24
sp|O33335|TRUB_MYCTU TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 110 2e-23
emb|CAB36580.1| (AL035472) possible tRNA pseudouridine synthase ... 106 3e-22
sp|O66922|TRUB_AQUAE TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 106 5e-22
sp|P09171|TRUB_ECOLI TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 103 3e-21
sp|P74696|TRUB_SYNY3 TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 102 4e-21
sp|P45142|TRUB_HAEIN TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 102 6e-21
pir||C81091 tRNA pseudouridine synthase B NMB1374 [imported] - N... 101 1e-20
gb|AAA57969.1| (U18997) P35 [Escherichia coli] 101 2e-20
pir||H72093 tRNA pseudouridine synthase B CP0438 [imported] - Ch... 100 2e-20
pir||T35986 probable tRNA pseudouridine synthase - Streptomyces ... 100 2e-20
pir||G81851 pseudouridylate synthase (EC 4.2.1.70) B tRNA-specif... 100 2e-20
emb|CAA71695.1| (Y10692) yhbA [Yersinia enterocolitica] 99 5e-20
sp|O34273|TRUB_YEREN TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 99 5e-20
gb|AAK40721.1| tRNA pseudouridine synthase subunit A (truB) [Sul... 97 3e-19
pir||F71558 probable tRNA pseudouridine synthase - Chlamydia tra... 97 3e-19
pir||F81709 tRNA pseudouridine synthase B TC0369 [imported] - Ch... 94 2e-18
sp|P57456|TRUB_BUCAI TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 93 4e-18
pir||D82831 tRNA pseudouridine synthase B XF0237 [imported] - Xy... 91 1e-17
pir||E72696 probable nucleolar protein APE0989 - Aeropyrum perni... 90 3e-17
pir||T44263 tRNA-pseudouridine 55 synthase (EC 5.4.99.-) [import... 89 1e-16
pir||T48619 tRNA synthase-like protein - Arabidopsis thaliana >g... 85 8e-16
gb|AAD50463.1|AF169967_6 (AF169967) TruB [Flavobacterium johnson... 84 2e-15
emb|CAA63512.1| (X92946) hypothetical protein [Lactococcus lactis] 83 6e-15
pir||B82902 tRNA pseudouridine 55 synthase UU354 [imported] - Ur... 77 3e-13
gb|AAB48163.1| (U54794) Orp [Pseudomonas aeruginosa] 76 7e-13
sp|P72154|TRUB_PSEAE TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 76 7e-13
sp|O51743|TRUB_BORBU TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOU... 73 6e-12
>pir||E75170 probable pseudouridylate synthase (EC 4.2.1.70) B PAB0356 -
Pyrococcus abyssi (strain Orsay)
>gi|5457954|emb|CAB49444.1| (AJ248284) PROBABLE TRNA
PSEUDOURIDINE SYNTHASE B (EC 4.2.1.70) (TRNA
PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE)
(PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE)
[Pyrococcus abyssi]
Length = 334
Score = 677 bits (1729), Expect = 0.0
Identities = 334/334 (100%), Positives = 334/334 (100%)
Query: 1 MARDEVRRILPADIKREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSH 60
MARDEVRRILPADIKREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSH
Sbjct: 1 MARDEVRRILPADIKREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSH 60
Query: 61 EVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDV 120
EVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDV
Sbjct: 61 EVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDV 120
Query: 121 PEDKIRAVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYI 180
PEDKIRAVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYI
Sbjct: 121 PEDKIRAVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYI 180
Query: 181 RSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAI 240
RSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAI
Sbjct: 181 RSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAI 240
Query: 241 QPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALG 300
QPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALG
Sbjct: 241 QPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALG 300
Query: 301 KAMMSTQEMIERSKGIAVDVEKVFMPRDWYPKLW 334
KAMMSTQEMIERSKGIAVDVEKVFMPRDWYPKLW
Sbjct: 301 KAMMSTQEMIERSKGIAVDVEKVFMPRDWYPKLW 334
>sp|O59357|TRUB_PYRHO PROBABLE TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55
SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE)
(URACIL HYDROLYASE) >gi|7444627|pir||D71044
tRNA-pseudouridine synthase (EC 5.4.99.-) PH1644 -
Pyrococcus horikoshii >gi|3258073|dbj|BAA30756.1|
(AP000006) 334aa long hypothetical
centromere/microtubule binding protein [Pyrococcus
horikoshii]
Length = 334
Score = 645 bits (1647), Expect = 0.0
Identities = 313/334 (93%), Positives = 329/334 (97%)
Query: 1 MARDEVRRILPADIKREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSH 60
MARDEVRR+LPADIKREV++KD+ AETNPKWGFPP +RPIELHIQYGVINLDKPPGPTSH
Sbjct: 1 MARDEVRRMLPADIKREVLIKDENAETNPKWGFPPYERPIELHIQYGVINLDKPPGPTSH 60
Query: 61 EVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDV 120
EVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALE+ATRVVQALLPAGKEYVALMHLHGDV
Sbjct: 61 EVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDV 120
Query: 121 PEDKIRAVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYI 180
PE+KI VMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLF+VGVEAGTYI
Sbjct: 121 PENKIIDVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLFKVGVEAGTYI 180
Query: 181 RSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAI 240
RSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIE+Y+R+AI
Sbjct: 181 RSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEKYLRRAI 240
Query: 241 QPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALG 300
QPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLN GIK+GDLVAIMTLKDELVALG
Sbjct: 241 QPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNVGIKRGDLVAIMTLKDELVALG 300
Query: 301 KAMMSTQEMIERSKGIAVDVEKVFMPRDWYPKLW 334
KAMM++QEM++RSKGIAVDVEKVFMPRDWYPKLW
Sbjct: 301 KAMMTSQEMMQRSKGIAVDVEKVFMPRDWYPKLW 334
>sp|Q57612|TRUB_METJA PROBABLE TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55
SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE)
(URACIL HYDROLYASE) >gi|2127807|pir||E64318
tRNA-pseudouridine synthase (EC 5.4.99.-) MJ0148 -
Methanococcus jannaschii >gi|1590909|gb|AAB98132.1|
(U67472) centromere/microtubule-binding protein (cbf5)
[Methanococcus jannaschii]
Length = 336
Score = 370 bits (940), Expect = e-101
Identities = 187/320 (58%), Positives = 239/320 (74%), Gaps = 2/320 (0%)
Query: 15 KREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEK 74
K E+IVK++ ETN +G P +R IE I+YGV+ +DKP GPTSHEV W+K+ILNL+K
Sbjct: 15 KEELIVKEE-VETNWDYGCNPYERKIEDLIKYGVVVVDKPRGPTSHEVSTWVKKILNLDK 73
Query: 75 AGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEG 134
AGHGGTLDPKV+GVLPVALERAT+ + KEYV LMHLH D E+ I V KEF G
Sbjct: 74 AGHGGTLDPKVTGVLPVALERATKTIPMWHIPPKEYVCLMHLHRDASEEDILRVFKEFTG 133
Query: 135 EIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVG 194
I QRPPL++AVKRRLR RK++ +E+L+ DG+DVLFRV ++GTYIR L IG ALG
Sbjct: 134 RIYQRPPLKAAVKRRLRIRKIHELELLDKDGKDVLFRVKCQSGTYIRKLCEDIGEALGTS 193
Query: 195 AHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIW 254
AHM ELRRT+SG F+E + V L DL+D Y FWKEDG EE +R+ I+PME + HL K+
Sbjct: 194 AHMQELRRTKSGCFEEKDA-VYLQDLLDAYVFWKEDGDEEELRRVIKPMEYGLRHLKKVV 252
Query: 255 IKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSK 314
+KDSAV A+ HGA++ V GI KL+ GI KG+ V + TLK E VA+GKA+M+T+E++ K
Sbjct: 253 VKDSAVDAICHGADVYVRGIAKLSKGIGKGETVLVETLKGEAVAVGKALMNTKEILNADK 312
Query: 315 GIAVDVEKVFMPRDWYPKLW 334
G+AVDVE+V+M R YP++W
Sbjct: 313 GVAVDVERVYMDRGTYPRMW 332
>sp|O26140|TRUB_METTH PROBABLE TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55
SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE)
(URACIL HYDROLYASE) >gi|7444628|pir||A69141
tRNA-pseudouridine synthase (EC 5.4.99.-) MTH32 -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621069|gb|AAB84541.1| (AE000796)
centromere/microtubule-binding protein [Methanobacterium
thermoautotrophicum]
Length = 324
Score = 367 bits (933), Expect = e-101
Identities = 180/311 (57%), Positives = 229/311 (72%), Gaps = 1/311 (0%)
Query: 24 KAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDP 83
+A TNP +G PP +R IE HI GV+NLDKP GPTSH+V +W++ +L++EK GHGGTLDP
Sbjct: 14 EATTNPDYGCPPAERDIEAHISMGVVNLDKPSGPTSHQVDSWVRDMLHVEKVGHGGTLDP 73
Query: 84 KVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQRPPLR 143
KV+GVLP+ ++RATRV+Q LL A KEYV LM +H +V E++IR V+ EF+G+I Q PPL+
Sbjct: 74 KVTGVLPLGIDRATRVMQLLLEAPKEYVCLMRVHREVDEERIREVLGEFQGKIFQIPPLK 133
Query: 144 SAVKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRT 203
SAVKR LR R +Y ++ILE+DG+DVLFR+ EAGTY+R H +G ALG GAHMAELRRT
Sbjct: 134 SAVKRDLRVRTIYRVDILEVDGQDVLFRIACEAGTYVRKYCHDVGEALGAGAHMAELRRT 193
Query: 204 RSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAV 263
GPF E E LVTLHDL D Y FW EDG E ++R+ I PME AV HLP++ I DSAV A+
Sbjct: 194 AVGPFTE-EGLVTLHDLKDAYQFWVEDGDETFLRECILPMEFAVGHLPRVVILDSAVDAI 252
Query: 264 AHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKV 323
HGA+L GI L+ I GD VAIMTLK ELV +G+A MS ++ G+ ++ KV
Sbjct: 253 CHGADLARGGIAGLDDNIAWGDTVAIMTLKGELVGVGEASMSALDIAAADGGLVIETRKV 312
Query: 324 FMPRDWYPKLW 334
FM YP++W
Sbjct: 313 FMEPGTYPRMW 323
>gi|11497854 centromere/microtubule-binding protein (cbf5) [Archaeoglobus
fulgidus] >gi|3915164|sp|O30001|TRUB_ARCFU PROBABLE TRNA
PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55
SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE)
(URACIL HYDROLYASE) >gi|7444629|pir||F69279
tRNA-pseudouridine synthase (EC 5.4.99.-) AF0238 -
Archaeoglobus fulgidus >gi|2650403|gb|AAB90995.1|
(AE001089) centromere/microtubule-binding protein (cbf5)
[Archaeoglobus fulgidus]
Length = 325
Score = 357 bits (906), Expect = 1e-97
Identities = 176/315 (55%), Positives = 230/315 (72%), Gaps = 2/315 (0%)
Query: 20 VKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGG 79
VKDD A T+ +G P KRP+E +I+ G++ +DKP GP+SHEVV W++RILN+ K GH G
Sbjct: 8 VKDD-ASTDESYGCYPTKRPMEEYIRKGLVCIDKPMGPSSHEVVVWVRRILNVSKTGHAG 66
Query: 80 TLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQR 139
TLDP+V+GVLP+ +E AT++V+ L + KEYV LM LHGD + + VMK F G I QR
Sbjct: 67 TLDPRVTGVLPIFIENATKMVKFLQESSKEYVCLMRLHGDAKREDVEKVMKLFVGRIYQR 126
Query: 140 PPLRSAVKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAE 199
PPL+SAVK+ LR R++Y +E+LE++GRDVLFRV E+GTYIR L IG LG GAHM E
Sbjct: 127 PPLKSAVKKVLRIREIYEMELLEMEGRDVLFRVVTESGTYIRKLCRDIGEVLGTGAHMQE 186
Query: 200 LRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSA 259
LRRTR+G F ED TL DL+D Y FWKE+G E+Y+R+ I+PME A LPKI IKDSA
Sbjct: 187 LRRTRTGKFGED-MCYTLQDLLDAYVFWKEEGEEKYLREIIKPMEVAAAELPKIVIKDSA 245
Query: 260 VAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVD 319
V A+ HGANL+V G+ + +KK VAI TLK+ELVA+G+A+M +++ KGIA D
Sbjct: 246 VDAICHGANLSVRGVAYVEKNVKKDSTVAIFTLKNELVAIGRALMDAEDIYRLKKGIAAD 305
Query: 320 VEKVFMPRDWYPKLW 334
+++V M R YPK+W
Sbjct: 306 IQRVMMERGVYPKVW 320
>sp|O43100|CBF5_EMENI CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 (CENTROMERE-BINDING
FACTOR 5) (NUCLEOLAR PROTEIN CBF5)
>gi|2737888|gb|AAB94296.1| (U59148) nucleolar protein
AnCbf5p [Aspergillus nidulans]
Length = 481
Score = 290 bits (734), Expect = 2e-77
Identities = 150/307 (48%), Positives = 202/307 (64%), Gaps = 4/307 (1%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR ++ +I GVINLDKP P+SHEVVAW+KRIL EK GH GTLDPKV+G L V
Sbjct: 46 GSSPLKRDLKSYINSGVINLDKPSNPSSHEVVAWMKRILRAEKTGHSGTLDPKVTGCLIV 105
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVP--EDKIRAVMKEFEGEIIQRPPLRSAVKRR 149
++RATR+V++ AGKEYV ++ LH +P E + + ++ G + QRPPL SAVKR+
Sbjct: 106 CIDRATRLVKSQQGAGKEYVCVIRLHDKIPGGEAQFKRALETLTGALFQRPPLISAVKRQ 165
Query: 150 LRTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGP 207
LR R ++ ++ E D L F V EAGTYIR+L H+GL LGVGAHM ELRR RSG
Sbjct: 166 LRIRTIHESKLYEFDNERHLGVFWVSCEAGTYIRTLCVHLGLLLGVGAHMQELRRVRSGA 225
Query: 208 FKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGA 267
E+E +VTLHD++D + E Y+RK I+P+E + +I +KDSAV AV +GA
Sbjct: 226 MSENEGMVTLHDVLDAQWLYDNQRDESYLRKVIKPLESLLTTYKRIVVKDSAVNAVCYGA 285
Query: 268 NLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPR 327
L +PG+++ AGI+ G+ V +MT K E +A+G A MST E+ G+ V++ M R
Sbjct: 286 KLMIPGLLRFEAGIELGEEVVLMTTKGEAIAIGIAQMSTVELSTCDHGVVAKVKRCIMER 345
Query: 328 DWYPKLW 334
D YP+ W
Sbjct: 346 DLYPRRW 352
>pir||T47775 hypothetical protein F24I3.230 - Arabidopsis thaliana
>gi|6911885|emb|CAB72185.1| (AL138655) putative protein
[Arabidopsis thaliana]
>gi|8901186|gb|AAF43210.2|AF234984_1 (AF234984) putative
pseudouridine synthase [Arabidopsis thaliana]
Length = 565
Score = 287 bits (726), Expect = 2e-76
Identities = 146/306 (47%), Positives = 200/306 (64%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KRP++ +I+YGVINLDKP P+SHEVVAWIKRIL +EK GH GTLDPKV+G L V
Sbjct: 66 GHSPLKRPLQEYIRYGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGNLIV 125
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPE-DKIRAVMKEFEGEIIQRPPLRSAVKRRL 150
++RATR+V++ AGKEYV + LH VP+ K+ ++ G + QRPPL SAVKR+L
Sbjct: 126 CIDRATRLVKSQQGAGKEYVCVARLHSAVPDVAKVARALESLTGAVFQRPPLISAVKRQL 185
Query: 151 RTRKVYYIEILEIDGRD--VLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y ++LE D V+F V EAGTYIR++ H+GL LGVG HM ELRR RSG
Sbjct: 186 RIRTIYESKLLEYDADRHLVVFWVSCEAGTYIRTMCVHLGLLLGVGGHMQELRRVRSGIL 245
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E+ +VT+HD++D + E Y+R+ I P+E + ++ +KDSAV A+ +GA
Sbjct: 246 GENNNMVTMHDVMDAQFVYDNSRDESYLRRVIMPLEMILTSYKRLVVKDSAVNAICYGAK 305
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
L +PG+++ I G V +MT K E +A+G A M+T M G+ +++V M RD
Sbjct: 306 LMIPGLLRFENDIDVGTEVVLMTTKGEAIAVGIAEMTTSVMATCDHGVVAKIKRVVMDRD 365
Query: 329 WYPKLW 334
YP+ W
Sbjct: 366 TYPRKW 371
>gb|AAF77119.1|AF234319_1 (AF234319) Cbf5p [Euglena gracilis]
Length = 467
Score = 286 bits (725), Expect = 2e-76
Identities = 135/306 (44%), Positives = 207/306 (67%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KRPI+ ++QYG +NLDKP P+SHEVV+W+KRIL +EK GH GTLDPKV+G L +
Sbjct: 51 GHTPLKRPIKAYLQYGCLNLDKPSNPSSHEVVSWLKRILKVEKTGHAGTLDPKVTGSLLI 110
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
+ERATR+V++ AGKEYV ++ LH + ++ ++ +++ G + QRPP+ +AVKR L
Sbjct: 111 CIERATRLVKSQQNAGKEYVGVLRLHDALKDEAQLLKALEDLTGAVFQRPPVVAAVKRTL 170
Query: 151 RTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y ++L+ D L F + EAGTY+R+L H+G LG HMAELRRTR+G
Sbjct: 171 RIRTIYESKLLDFDNDRHLAVFWISCEAGTYVRTLCVHLGFVLGTAGHMAELRRTRTGHL 230
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E++ +VT+HD++D H + ++G E Y+R+ + P E + ++ +KD+AV A+ +GA
Sbjct: 231 GENDGMVTMHDVLDAMHLYDQEGDESYLRRTVMPCELLLTAYKRVVVKDTAVNAICYGAK 290
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
L +PG+++ GI+ +++ +MT K E +ALG A+M+T +M GI +++V M RD
Sbjct: 291 LMIPGLLRFENGIEVNEVIVLMTTKGEAIALGIALMTTADMGTCDHGIVAKIKRVVMDRD 350
Query: 329 WYPKLW 334
YP+ W
Sbjct: 351 TYPRRW 356
>sp|O43102|CBF5_ASPFU CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 (CENTROMERE-BINDING
FACTOR 5) (NUCLEOLAR PROTEIN CBF5)
>gi|2737892|gb|AAB94298.1| (U59150) nucleolar protein
AfCbf5p [Aspergillus fumigatus]
Length = 487
Score = 286 bits (723), Expect = 3e-76
Identities = 149/307 (48%), Positives = 200/307 (64%), Gaps = 4/307 (1%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR ++ +I GVINLDKP P+SHEVVAW+KRIL EK GH GTLDPKV+G L V
Sbjct: 51 GCSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWMKRILRAEKTGHSGTLDPKVTGCLIV 110
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVP--EDKIRAVMKEFEGEIIQRPPLRSAVKRR 149
++RATR+V++ AGKEYV ++ LH +P E + + ++ G + QRPPL SAVKR+
Sbjct: 111 CIDRATRLVKSQQGAGKEYVCVIRLHDKIPGGEAQFKRALETLTGALFQRPPLISAVKRQ 170
Query: 150 LRTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGP 207
LR R ++ ++ E D L F V EAGTYIR+L H+GL LGVGAHM ELRR RSG
Sbjct: 171 LRIRTIHESKLYEFDNDRHLGVFWVSCEAGTYIRTLCVHLGLLLGVGAHMQELRRVRSGA 230
Query: 208 FKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGA 267
E+ LVTLHD++D + E Y+R+ IQP+E + +I +KDSAV AV +GA
Sbjct: 231 MDENNGLVTLHDVLDAQWMYDNQRDESYLRRVIQPLESLLTTYKRIVVKDSAVNAVCYGA 290
Query: 268 NLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPR 327
L +PG+++ AGI+ + V +MT K E +A+G A MST E+ G+ V++ M R
Sbjct: 291 KLMIPGLLRFEAGIEVNEEVVLMTTKGEAIAIGIAQMSTVELSTCDHGVVAKVKRCIMER 350
Query: 328 DWYPKLW 334
D YP+ W
Sbjct: 351 DLYPRRW 357
>sp|O43101|CBF5_CANAL CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 (CENTROMERE-BINDING
FACTOR 5) (NUCLEOLAR PROTEIN CBF5)
>gi|2737890|gb|AAB94297.1| (U59149) nucleolar protein
CaCbf5p [Candida albicans]
Length = 479
Score = 285 bits (722), Expect = 4e-76
Identities = 146/306 (47%), Positives = 200/306 (64%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P R I+ ++ GVINLDKP P+SHEVVAWIKRIL +EK GH GTLDPKV+G L V
Sbjct: 46 GSAPLNRDIKSYVSSGVINLDKPSNPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIV 105
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPEDK-IRAVMKEFEGEIIQRPPLRSAVKRRL 150
++RATR+V++ AGKEYV ++ LH + +DK + ++ G + QRPPL SAVKR+L
Sbjct: 106 CIDRATRLVKSQQGAGKEYVCIVRLHEQLKDDKELNRALENLTGALFQRPPLISAVKRQL 165
Query: 151 RTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R VY +++E D + L F EAGTY+R+L H+G+ LGVG HM ELRR RSG
Sbjct: 166 RVRTVYDSKLIEFDNKRGLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGAM 225
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + LVTLHD++D + + E Y+RK IQP+E + ++ +KDSAV +V +GA
Sbjct: 226 SESDNLVTLHDVLDAQYVYDNTRDESYLRKIIQPLESLLVGYKRVVVKDSAVNSVCYGAK 285
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
L +PG+++ GI+ D V +MT K E +A+G A MST ++ GI V++ M RD
Sbjct: 286 LMIPGLLRYEEGIELYDEVVLMTTKGEAIAIGIAQMSTVDLQSCDHGIVAKVKRCIMERD 345
Query: 329 WYPKLW 334
YP+ W
Sbjct: 346 TYPRRW 351
>emb|CAB85492.1| (AJ277097) putative kinetochore protein [Hordeum vulgare]
Length = 405
Score = 279 bits (705), Expect = 4e-74
Identities = 141/306 (46%), Positives = 196/306 (63%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KRP+ +++YGVINLDKP P+SHEVVAWIKR+L +EK GH GTLDPKV+G L V
Sbjct: 88 GHSPLKRPLAEYLRYGVINLDKPSNPSSHEVVAWIKRLLRVEKTGHSGTLDPKVTGNLIV 147
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
++RATR+V++ AGKEYV + H VP+ ++ ++ G + QRPPL SAVKR+L
Sbjct: 148 CVDRATRLVKSQQGAGKEYVCIARFHAAVPDTARVARALESLTGAVFQRPPLISAVKRQL 207
Query: 151 RTRKVYYIEILEIDGRD--VLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y ++LE D +F + EAGTY+R+L H+GL LGVGAHM ELRR RSG
Sbjct: 208 RVRTIYESKLLEHDAERHLAVFWISCEAGTYVRTLCVHLGLLLGVGAHMQELRRVRSGIL 267
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D E YIR+ + P+E + ++ +KDSAV A+ +GA
Sbjct: 268 GEQDNMVTMHDVMDAMWALDNHKDESYIRRVVMPLEVILTSYKRLVVKDSAVNAICYGAK 327
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
L +PG+++ I G+ V +MT K E +A+G A M T M G +++V M RD
Sbjct: 328 LMIPGLLRFENDIDVGEEVVLMTTKGEAIAIGIAEMPTAVMATCDHGAVAKIKRVVMDRD 387
Query: 329 WYPKLW 334
YP+ W
Sbjct: 388 TYPRKW 393
>emb|CAB86704.1| (AL163505) probable dyskerin [Leishmania major]
Length = 430
Score = 279 bits (705), Expect = 4e-74
Identities = 136/305 (44%), Positives = 199/305 (64%), Gaps = 2/305 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G+ P +RP+ +I+YG+IN+DKP P+SHEVV+WIKRIL +K GH GTLDPKV+G L +
Sbjct: 56 GWSPLRRPLAEYIKYGMINMDKPSNPSSHEVVSWIKRILKCDKTGHAGTLDPKVTGALII 115
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQRPPLRSAVKRRLR 151
+RATR+V++ AGK Y+ ++ LH V + K+ A ++ G QRPPL +AVKR+LR
Sbjct: 116 CTDRATRLVKSQQNAGKTYIGVLRLHDTVSQKKVDAALQRLTGPCFQRPPLIAAVKRQLR 175
Query: 152 TRKVYYIEILEIDGRD--VLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFK 209
R +Y +++E D +F EAGTYIR+L H+GL LG G HM ELRR R+G
Sbjct: 176 IRNIYSNQLIEYDKHRHLAVFETHCEAGTYIRTLCVHVGLILGAGGHMEELRRIRTGVIT 235
Query: 210 EDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGANL 269
E++ L T+HD++D ++ + + Y+R+ I P E + + +I +KDSAV AV +GA L
Sbjct: 236 ENDHLSTMHDVMDAQWLYENEKDDTYLRRVILPCEYLLSNHKRIVVKDSAVNAVCYGAKL 295
Query: 270 TVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRDW 329
+PG+ + + GI++ D+V +MT K E +AL A M+T +M GI ++V M RD
Sbjct: 296 MIPGLARFDNGIERDDVVVLMTTKGEAIALAYAEMTTSQMASVDHGIVARSKRVIMDRDT 355
Query: 330 YPKLW 334
YP+ W
Sbjct: 356 YPRRW 360
>sp|O14007|CBF5_SCHPO CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 (CENTROMERE-BINDING
FACTOR 5) (NUCLEOLAR PROTEIN CBF5)
>gi|7490221|pir||T38485 centromere/microtubule binding
protein cbf5 - fission yeast (Schizosaccharomyces
pombe) >gi|2239214|emb|CAB10131.1| (Z97210)
centromere/microtubule binding protein cbf5
[Schizosaccharomyces pombe]
Length = 474
Score = 277 bits (702), Expect = 1e-73
Identities = 140/306 (45%), Positives = 199/306 (64%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KRPI ++ GVINLDKP P+SHEVVAW+K+IL +EK GH GTLDPKV+G L +
Sbjct: 50 GNNPLKRPIAEYVSSGVINLDKPANPSSHEVVAWVKKILRVEKTGHSGTLDPKVTGCLII 109
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVP-EDKIRAVMKEFEGEIIQRPPLRSAVKRRL 150
+RATR+V++ AGKEYV ++ LH V E + + ++ G + QRPPL SAVKR+L
Sbjct: 110 CNDRATRLVKSQQSAGKEYVCVLRLHDSVEGERNVASAIETLTGALFQRPPLISAVKRQL 169
Query: 151 RTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y +++E D L F EAGTY+R+L H+GL LGVG HM ELRR RSG
Sbjct: 170 RIRSIYESKLIEFDNERNLAVFWASCEAGTYMRTLCVHLGLLLGVGGHMQELRRVRSGCL 229
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E++ +VT+HD++D + E Y+R+ I+P+E + +I +KDSAV A+ +GA
Sbjct: 230 SENDDIVTMHDVLDAQWIYDNTRDESYLRRVIRPLESLLVGYKRIVVKDSAVNAICYGAK 289
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
L +PG+++ AGI+ + + ++T K E +A+G A MST E+ G+ V++ M RD
Sbjct: 290 LMIPGLLRYEAGIEVNEEIVLITTKGEAIAVGIAQMSTVELSTCDHGVVAKVKRCIMERD 349
Query: 329 WYPKLW 334
YP+ W
Sbjct: 350 VYPRRW 355
>gb|AAG38982.1|AC082644_19 (AC082644) putative centromere/microtubule binding protein [Oryza
sativa]
Length = 591
Score = 277 bits (702), Expect = 1e-73
Identities = 141/306 (46%), Positives = 198/306 (64%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KRPI +++YGVINLDKP P+SHEVVAWIKR+L +EK GH GTLDPKV+G L V
Sbjct: 93 GHSPLKRPIAEYLRYGVINLDKPSNPSSHEVVAWIKRLLRVEKTGHSGTLDPKVTGNLIV 152
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
++RATR+V++ AGKEYV + H VP+ ++ ++ G + QRPPL SAVKR+L
Sbjct: 153 CVDRATRLVKSQQGAGKEYVCVARFHAAVPDTARVARALEALTGAVFQRPPLISAVKRQL 212
Query: 151 RTRKVYYIEILE--IDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y ++LE D +F + EAGTY+R+L H+GL LGVGAHM ELRR RSG
Sbjct: 213 RVRTIYESKLLEHDADRHLAVFWISCEAGTYVRTLCVHLGLLLGVGAHMQELRRVRSGIL 272
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D E Y+R+ + P+E + ++ +KDSAV A+ +GA
Sbjct: 273 GETDNMVTMHDVMDARWAMDNFNDESYLRRIVMPLEVLLTSYKRLVVKDSAVNAICYGAK 332
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
L +PG+++ I+ G+ V +MT K E +A+G A M+T M G +++V M RD
Sbjct: 333 LMIPGLLRFENEIEVGEEVVLMTTKGEAIAIGIAEMTTAVMATCDHGAVAKIKRVVMDRD 392
Query: 329 WYPKLW 334
YP+ W
Sbjct: 393 TYPRKW 398
>sp|O13473|CBF5_KLULA CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 (CENTROMERE-BINDING
FACTOR 5) (NUCLEOLAR PROTEIN CBF5)
>gi|2258455|gb|AAC64862.1| (AF008563) centromere-binding
factor 5 [Kluyveromyces lactis]
Length = 474
Score = 277 bits (700), Expect = 2e-73
Identities = 144/306 (47%), Positives = 198/306 (64%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR ++ +I GVINLDKP P+SHEVVAWIKRIL EK GH GTLDPKV+G L V
Sbjct: 44 GASPLKRDLKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIV 103
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPEDK-IRAVMKEFEGEIIQRPPLRSAVKRRL 150
++RATR+V++ AGKEYV ++ LH + ++K + ++ G + QRPPL SAVKR+L
Sbjct: 104 CVDRATRLVKSQQGAGKEYVCIVRLHDALKDEKELGRGLENLTGALFQRPPLISAVKRQL 163
Query: 151 RTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y ++E D + L F EAGTY+R+L H+G+ LGVG HM ELRR RSG
Sbjct: 164 RVRTIYDSNLIEFDNKRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGAL 223
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E++ LVTLHD++D + E Y+RK IQP+E + +I +KDSAV AV +GA
Sbjct: 224 SENDNLVTLHDVMDAQWVYDNTRDESYLRKIIQPLETLLVGYKRIVVKDSAVNAVCYGAK 283
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
L +PG+++ GI+ D V ++T K E +A+ A MST ++ G+ V++ M RD
Sbjct: 284 LMIPGLLRYEEGIELYDEVVLITTKGEAIAVAIAQMSTVDLATCDHGVVAKVKRCIMERD 343
Query: 329 WYPKLW 334
YP+ W
Sbjct: 344 LYPRRW 349
>gi|6323204 major low affinity 55 kDa Centromere/microtubule binding protein;
Cbf5p [Saccharomyces cerevisiae]
>gi|461698|sp|P33322|CBF5_YEAST CENTROMERE/MICROTUBULE
BINDING PROTEIN CBF5 (CENTROMERE-BINDING FACTOR 5)
(NUCLEOLAR PROTEIN CBF5) (P64') >gi|542251|pir||S41853
centromere/microtubule-binding protein CBF5 [validated]
- yeast (Saccharomyces cerevisiae)
>gi|311097|gb|AAA34473.1| (L12351)
centromere/microtubule binding protein [Saccharomyces
cerevisiae] >gi|577203|gb|AAB67463.1| (U17246) Cbf5p:
centromere/microtubule binding protein [Saccharomyces
cerevisiae]
Length = 483
Score = 275 bits (697), Expect = 4e-73
Identities = 141/306 (46%), Positives = 197/306 (64%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR ++ +I GVINLDKP P+SHEVVAWIKRIL EK GH GTLDPKV+G L V
Sbjct: 45 GSSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIV 104
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPEDK-IRAVMKEFEGEIIQRPPLRSAVKRRL 150
++RATR+V++ AGKEYV ++ LH + ++K + ++ G + QRPPL SAVKR+L
Sbjct: 105 CIDRATRLVKSQQGAGKEYVCIVRLHDALKDEKDLGRSLENLTGALFQRPPLISAVKRQL 164
Query: 151 RTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y ++E D + L F EAGTY+R+L H+G+ LGVG HM ELRR RSG
Sbjct: 165 RVRTIYESNLIEFDNKRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGAL 224
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E++ +VTLHD++D + E Y+R IQP+E + +I +KDSAV AV +GA
Sbjct: 225 SENDNMVTLHDVMDAQWVYDNTRDESYLRSIIQPLETLLVGYKRIVVKDSAVNAVCYGAK 284
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
L +PG+++ GI+ D + ++T K E +A+ A MST ++ G+ V++ M RD
Sbjct: 285 LMIPGLLRYEEGIELYDEIVLITTKGEAIAVAIAQMSTVDLASCDHGVVASVKRCIMERD 344
Query: 329 WYPKLW 334
YP+ W
Sbjct: 345 LYPRRW 350
>pir||F72696 probable nucleolar protein APE0990 - Aeropyrum pernix (strain K1)
>gi|5104659|dbj|BAA79974.1| (AP000060) 293aa long
hypothetical nucleolar protein [Aeropyrum pernix]
Length = 293
Score = 273 bits (692), Expect = 1e-72
Identities = 135/260 (51%), Positives = 182/260 (69%), Gaps = 1/260 (0%)
Query: 76 GHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGE 135
G G PKV+GVLPVALER TR++ ++ + KEYV +M LH V ED++R V+K FEGE
Sbjct: 25 GAAGRGYPKVTGVLPVALERMTRIIGTVMHSSKEYVCVMQLHRPVEEDRLREVLKLFEGE 84
Query: 136 IIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGA 195
I Q+PPLRS+VKR LRTR+V+ IE+LE G+ L RV EAGTY+R L IGL LGVGA
Sbjct: 85 IYQKPPLRSSVKRALRTRRVFRIELLEYTGKYALLRVDCEAGTYMRKLCWDIGLVLGVGA 144
Query: 196 HMAELRRTRSGPFKEDETLVTLHDLVDYYHF-WKEDGIEEYIRKAIQPMEKAVEHLPKIW 254
HM ELRR R+GPF ED L+ D V Y W+E+G ++ +R+ + P E +V H+PK+
Sbjct: 145 HMRELRRIRTGPFSEDSGLMVRLDDVAYAVIRWREEGKDDLLRRVVIPGEYSVCHIPKVL 204
Query: 255 IKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSK 314
++DSAV ++ HGA L PG+ + G++KG +VA+MTLK EL+ LGKA+ S QEM+E +
Sbjct: 205 VRDSAVESLTHGAQLAAPGVAAVEEGVEKGGMVALMTLKGELIGLGKALASAQEMLEAER 264
Query: 315 GIAVDVEKVFMPRDWYPKLW 334
GI V ++ M R YP++W
Sbjct: 265 GIVVSPTRIIMERGLYPRMW 284
>sp|O44081|NO60_DROME NUCLEOLAR PROTEIN AT BAND 60B >gi|2661227|gb|AAC97117.1| (AF017230)
nucleolar protein at band 60B [Drosophila melanogaster]
>gi|4322557|gb|AAD16092.1| (AF089837) minifly protein
[Drosophila melanogaster] >gi|7291757|gb|AAF47178.1|
(AE003463) Nop60B gene product [Drosophila melanogaster]
Length = 508
Score = 263 bits (666), Expect = 2e-69
Identities = 139/306 (45%), Positives = 201/306 (65%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P R I+ +++ G INLDKP P+SHEVVAWIK+IL +EK GH GTLDPKV+G L V
Sbjct: 73 GSSPLNRDIKEYMKTGFINLDKPSNPSSHEVVAWIKKILKVEKTGHSGTLDPKVTGCLIV 132
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPE-DKIRAVMKEFEGEIIQRPPLRSAVKRRL 150
++RATR+V++ AGKEYVA+ LHG V K+R +++ G + QRPPL SAVKR+L
Sbjct: 133 CIDRATRLVKSQQSAGKEYVAIFKLHGAVESVAKVRQGLEKLRGALFQRPPLISAVKRQL 192
Query: 151 RTRKVYYIEILEIDG-RDV-LFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R VY ++L+ D R++ +F V EAG+YIR++ H+GL LGVG M ELRR RSG
Sbjct: 193 RVRTVYDSKLLDYDETRNMGVFWVSCEAGSYIRTMCVHLGLVLGVGGQMLELRRVRSGIQ 252
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D ++ E +R+ I+P+E + + +I +KDS+V AV +GA
Sbjct: 253 SERDGMVTMHDVLDAMWLYENHKDESMLRRVIKPLEGLLVNHKRIIMKDSSVNAVCYGAK 312
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+T+PG+++ GI+ + I T K E + L A+M+T M G+ +++V M RD
Sbjct: 313 ITLPGVLRYEDGIEIDQEIVICTTKGEAICLAIALMTTATMASCDHGVVAKIKRVIMERD 372
Query: 329 WYPKLW 334
YP+ W
Sbjct: 373 TYPRKW 378
>gb|AAD19897.1| (AF097634) minifly protein [Drosophila melanogaster]
Length = 508
Score = 263 bits (666), Expect = 2e-69
Identities = 139/306 (45%), Positives = 201/306 (65%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P R I+ +++ G INLDKP P+SHEVVAWIK+IL +EK GH GTLDPKV+G L V
Sbjct: 73 GSSPLNRDIKEYMKTGFINLDKPSNPSSHEVVAWIKKILKVEKTGHSGTLDPKVTGCLIV 132
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPE-DKIRAVMKEFEGEIIQRPPLRSAVKRRL 150
++RATR+V++ AGKEYVA+ LHG V K+R +++ G + QRPPL SAVKR+L
Sbjct: 133 CIDRATRLVKSQQSAGKEYVAIFKLHGAVESVAKVRQGLEKLRGALFQRPPLISAVKRQL 192
Query: 151 RTRKVYYIEILEIDG-RDV-LFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R VY ++L+ D R++ +F V EAG+YIR++ H+GL LGVG M ELRR RSG
Sbjct: 193 RVRTVYDSKLLDYDETRNMGVFWVSCEAGSYIRTMCVHLGLVLGVGGQMLELRRVRSGIQ 252
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D ++ E +R+ I+P+E + + +I +KDS+V AV +GA
Sbjct: 253 SERDGMVTMHDVLDAMWLYENHKDESMLRRVIKPLEGLLVNHKRIIMKDSSVNAVCYGAK 312
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+T+PG+++ GI+ + I T K E + L A+M+T M G+ +++V M RD
Sbjct: 313 ITLPGVLRYEDGIEIDQEIVICTTKGEAICLAIALMTTATMASCDHGVVAKIKRVIMERD 372
Query: 329 WYPKLW 334
YP+ W
Sbjct: 373 TYPRKW 378
>gb|AAB94299.1| (U59151) Cbf5p homolog [Homo sapiens]
Length = 514
Score = 261 bits (659), Expect = 1e-68
Identities = 134/306 (43%), Positives = 195/306 (62%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR I +I+ G INLDKP P+SHEVVAWI+RIL +EK GH GTLDPKV+G L V
Sbjct: 75 GSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIV 134
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
+ERATR+V++ AGKEYV ++ LH + ++ ++ G + QRPPL +AVKR+L
Sbjct: 135 CIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPLIAAVKRQL 194
Query: 151 RTRKVYYIEILEIDG--RDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y +++E D R +F V EAGTYIR+L H+GL LGVG M ELRR RSG
Sbjct: 195 RVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVM 254
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D + E Y+R+ + P+EK + ++ +KDSAV A+ +GA
Sbjct: 255 SEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAK 314
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+ +PG+++ GI+ + ++T K E + + A+M+T + GI +++V M RD
Sbjct: 315 IMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERD 374
Query: 329 WYPKLW 334
YP+ W
Sbjct: 375 TYPRKW 380
>gi|4503337 dyskeratosis congenita 1, dyskerin; Dyskerin [Homo sapiens]
>gi|3913488|sp|O60832|DKC1_HUMAN DYSKERIN (NUCLEOLAR
PROTEIN NAP57) (CBF5 HOMOLOG)
>gi|3135028|emb|CAA11970.1| (AJ224481) dyskerin [Homo
sapiens] >gi|3873221|gb|AAD11815.1| (AF067008) dyskerin
[Homo sapiens] >gi|4416165|gb|AAD20232.1| (AF067023)
dyskerin [Homo sapiens]
Length = 514
Score = 261 bits (659), Expect = 1e-68
Identities = 134/306 (43%), Positives = 195/306 (62%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR I +I+ G INLDKP P+SHEVVAWI+RIL +EK GH GTLDPKV+G L V
Sbjct: 75 GSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIV 134
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
+ERATR+V++ AGKEYV ++ LH + ++ ++ G + QRPPL +AVKR+L
Sbjct: 135 CIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPLIAAVKRQL 194
Query: 151 RTRKVYYIEILEIDG--RDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y +++E D R +F V EAGTYIR+L H+GL LGVG M ELRR RSG
Sbjct: 195 RVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVM 254
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D + E Y+R+ + P+EK + ++ +KDSAV A+ +GA
Sbjct: 255 SEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAK 314
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+ +PG+++ GI+ + ++T K E + + A+M+T + GI +++V M RD
Sbjct: 315 IMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERD 374
Query: 329 WYPKLW 334
YP+ W
Sbjct: 375 TYPRKW 380
>emb|CAB51168.1| (AJ010395) dyskerin [Homo sapiens]
Length = 524
Score = 261 bits (659), Expect = 1e-68
Identities = 134/306 (43%), Positives = 195/306 (62%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR I +I+ G INLDKP P+SHEVVAWI+RIL +EK GH GTLDPKV+G L V
Sbjct: 75 GSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIV 134
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
+ERATR+V++ AGKEYV ++ LH + ++ ++ G + QRPPL +AVKR+L
Sbjct: 135 CIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPLIAAVKRQL 194
Query: 151 RTRKVYYIEILEIDG--RDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y +++E D R +F V EAGTYIR+L H+GL LGVG M ELRR RSG
Sbjct: 195 RVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVM 254
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D + E Y+R+ + P+EK + ++ +KDSAV A+ +GA
Sbjct: 255 SEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAK 314
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+ +PG+++ GI+ + ++T K E + + A+M+T + GI +++V M RD
Sbjct: 315 IMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERD 374
Query: 329 WYPKLW 334
YP+ W
Sbjct: 375 TYPRKW 380
>pir||A55163 nucleolar protein Nopp140, hepatic - rat >gi|1093316|prf||2103261A
nuclear protein NAP57 [Rattus norvegicus]
Length = 466
Score = 259 bits (654), Expect = 4e-68
Identities = 134/306 (43%), Positives = 194/306 (62%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR I +++ G INLDKP P+SHEVVAWI+RIL +EK GH GTLDPKV+G L V
Sbjct: 76 GSNPLKREIGEYVRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIV 135
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
+ERATR+V++ AGKEYV ++ LH + ++ ++ G + QRPPL +AVKR+L
Sbjct: 136 CIERATRLVKSQQSAGKEYVGVVRLHNAIEGTAQLSRALETLTGALFQRPPLIAAVKRQL 195
Query: 151 RTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y ++E D L F V EAGTYIR+L H+GL LGVG M ELRR RSG
Sbjct: 196 RVRTIYESRVVEYDPERRLGVFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVV 255
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D + + E Y+R+ + P+EK + ++ +KDSAV A+ +GA
Sbjct: 256 GERDHMVTMHDVLDAQYLYDHHRDESYLRRVVFPLEKLLTSHKRLVMKDSAVNAICYGAK 315
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+ +PG+++ GI+ V ++T K E V + A+M+T + G+ +++V M RD
Sbjct: 316 IMLPGLLRYEDGIEVNQEVVVITTKGEAVCVAIALMTTAVISTCDHGVVAKIKRVIMERD 375
Query: 329 WYPKLW 334
YP+ W
Sbjct: 376 TYPRKW 381
>sp|P40615|DKC1_RAT DYSKERIN (NUCLEOLAR PROTEIN NAP57) >gi|2739325|emb|CAA84402.1|
(Z34922) NAP57 [Rattus norvegicus]
Length = 509
Score = 259 bits (654), Expect = 4e-68
Identities = 134/306 (43%), Positives = 194/306 (62%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR I +++ G INLDKP P+SHEVVAWI+RIL +EK GH GTLDPKV+G L V
Sbjct: 76 GSNPLKREIGEYVRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIV 135
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
+ERATR+V++ AGKEYV ++ LH + ++ ++ G + QRPPL +AVKR+L
Sbjct: 136 CIERATRLVKSQQSAGKEYVGVVRLHNAIEGTAQLSRALETLTGALFQRPPLIAAVKRQL 195
Query: 151 RTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y ++E D L F V EAGTYIR+L H+GL LGVG M ELRR RSG
Sbjct: 196 RVRTIYESRVVEYDPERRLGVFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVV 255
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D + + E Y+R+ + P+EK + ++ +KDSAV A+ +GA
Sbjct: 256 GERDHMVTMHDVLDAQYLYDHHRDESYLRRVVFPLEKLLTSHKRLVMKDSAVNAICYGAK 315
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+ +PG+++ GI+ V ++T K E V + A+M+T + G+ +++V M RD
Sbjct: 316 IMLPGLLRYEDGIEVNQEVVVITTKGEAVCVAIALMTTAVISTCDHGVVAKIKRVIMERD 375
Query: 329 WYPKLW 334
YP+ W
Sbjct: 376 TYPRKW 381
>emb|CAC04528.1| (AJ250973) DYSKERIN [Mus musculus]
Length = 509
Score = 253 bits (640), Expect = 2e-66
Identities = 131/306 (42%), Positives = 192/306 (61%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR I +I+ G INLDKP P+SHEVVAWI+RIL +EK GH GTLDPKV+G L V
Sbjct: 75 GSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIV 134
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
+ERATR+V++ AGKEYV ++ LH + ++ ++ G + QRPPL +AVKR+L
Sbjct: 135 CIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPLIAAVKRQL 194
Query: 151 RTRKVYYIEILEIDG--RDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R +Y +++E D R +F V EAGTYIR+L H+ LG G M ELRR RSG
Sbjct: 195 RVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLCFVLGSGCQMQELRRVRSGVM 254
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E + +VT+HD++D + E Y+R+ + P+EK + ++ +KDSAV A+ +GA
Sbjct: 255 SEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAK 314
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+ +PG+++ GI+ + ++T K E + + A+M+T + GI +++V M RD
Sbjct: 315 IMLPGLLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERD 374
Query: 329 WYPKLW 334
YP+ W
Sbjct: 375 TYPRKW 380
>sp|O17919|NO50_CAEEL PUTATIVE NUCLEOLAR PROTEIN K01G5.5 >gi|7505086|pir||T23199
hypothetical protein K01G5.5 - Caenorhabditis elegans
>gi|3924791|emb|CAB07244.1| (Z92803) contains similarity
to Pfam domain: PF01472 (PUA domain), Score=99.5,
E-value=2.2e-26, N=1; PF01509 (TruB family
pseudouridylate synthase (N terminal domain)),
Score=261.8, E-value=2.9e-75, N=1~cDNA EST EMBL:T01400
comes from this gene~cDNA ES>
Length = 445
Score = 251 bits (635), Expect = 7e-66
Identities = 127/306 (41%), Positives = 188/306 (60%), Gaps = 3/306 (0%)
Query: 32 GFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPV 91
G P KR I+ +I G NLDKP P+SHEVV+WIKRIL EK GH GTLDPKVSG L V
Sbjct: 63 GVSPLKRDIKNYISSGFFNLDKPSNPSSHEVVSWIKRILRCEKTGHSGTLDPKVSGCLIV 122
Query: 92 ALERATRVVQALLPAGKEYVALMHLHGDVPED-KIRAVMKEFEGEIIQRPPLRSAVKRRL 150
++R TR+ ++ AGKEY+ + LH +V +D K++ +++ G + QRPPL SAVKR+L
Sbjct: 123 CIDRTTRLAKSQQGAGKEYICIFKLHEEVEDDRKVKQALEKLTGALFQRPPLISAVKRQL 182
Query: 151 RTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
R R VY + +E D + F E+GTY+R++ H+GL LG G M ELRR RSG
Sbjct: 183 RIRTVYENKFIEYDPAQQMGIFNCICESGTYVRTICVHLGLILGCGGQMQELRRNRSGIC 242
Query: 209 KEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGAN 268
E+E +VT+HD++D + E Y+R ++P+E + ++ +KDS + A+ +GA
Sbjct: 243 DENENMVTMHDVLDAQYLLDTQKDESYMRHIVRPLEALLTQHKRVVVKDSCINAICYGAK 302
Query: 269 LTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+ +PGI++ + I+ G + IM+ K E + + A M+T + G+ ++V M RD
Sbjct: 303 ILIPGILRYDDDIEVGKEIVIMSTKGEAICIAIAQMNTSTIASVDHGVVAKSKRVIMERD 362
Query: 329 WYPKLW 334
Y + W
Sbjct: 363 VYGRKW 368
>gb|AAG19966.1| (AE005078) tRNA-pseudouridine synthase; Sus [Halobacterium sp.
NRC-1]
Length = 301
Score = 247 bits (625), Expect = 1e-64
Identities = 137/302 (45%), Positives = 187/302 (61%), Gaps = 16/302 (5%)
Query: 34 PPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVAL 93
PP +R + +GV+NLDKPPGP++H+V AWI+ ++ +EKA H GTLDPKV+G LPV
Sbjct: 6 PPGERSPAAVLSFGVVNLDKPPGPSAHQVSAWIRDLVGVEKAAHAGTLDPKVTGCLPVLT 65
Query: 94 ERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQRPPLRSAVKRRLRTR 153
ATR+ ALL KEYVA++ LH D P + V++ F GEI Q+PP +SAV RRLRTR
Sbjct: 66 GTATRIAPALLEGFKEYVAVLELHDDPPR-ILPDVIEAFTGEIYQKPPKKSAVARRLRTR 124
Query: 154 KVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDET 213
VY +++L++DGR VL R+ E+GTYIR L H IG ALG AHM LRR+ + PF +D
Sbjct: 125 TVYDLDVLDVDGRQVLLRIRCESGTYIRKLCHDIGRALGTNAHMGHLRRSATTPF-DDTD 183
Query: 214 LVTLHDLVDYYHFWKE-------DGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHG 266
LVTLHDL D + ++ D + +R A+QP E+A+ HLP++ I DSA VA G
Sbjct: 184 LVTLHDLADAVAWLRDTDDTEPPDAPADALRAAVQPAERALTHLPRLTIADSAAHEVATG 243
Query: 267 ANLTVPGIVKLNA---GIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKV 323
A + PG++ A G LVA T V LG+ + + G+ V +E+V
Sbjct: 244 APVYAPGVIDTTALPTPPADGALVACYTAGGTAVCLGRLVGDP----DADAGVVVALERV 299
Query: 324 FM 325
+
Sbjct: 300 LV 301
>gb|AAK40720.1| tRNA pseudouridine synthase subunit B (truB) [Sulfolobus
solfataricus]
Length = 251
Score = 240 bits (606), Expect = 2e-62
Identities = 120/247 (48%), Positives = 169/247 (67%), Gaps = 1/247 (0%)
Query: 88 VLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQRPPLRSAVK 147
+LP+ +E AT+++ + GKEYV +M +H + ++++ ++ F+GEI QRPP+RS+VK
Sbjct: 1 MLPIGIENATKIMNYISKGGKEYVCVMQVHCEYNKEELAKIISSFKGEIYQRPPVRSSVK 60
Query: 148 RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGP 207
RRLR R++Y IEIL++D + VL RV ++GTY+R L H IG+ G GAHM ELRRTRSG
Sbjct: 61 RRLRIRRIYDIEILDMDKKLVLLRVNCDSGTYMRKLCHDIGIIYGCGAHMRELRRTRSGI 120
Query: 208 FKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGA 267
F E LV LH+L + + +K E +R+ + PME A +PKI I+DSAV A+A+GA
Sbjct: 121 FTESTNLVKLHELSEAIYLYKNCKDETELRRVLIPMEFATCEIPKIVIEDSAVNALAYGA 180
Query: 268 NLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPR 327
L VPG+V KK D VA++TLK ELVA G A+M ++E+ KGI V++ +VFM R
Sbjct: 181 QLAVPGVVAYQ-NFKKNDTVAVLTLKGELVATGNALMDSEELENAKKGIVVNLSRVFMQR 239
Query: 328 DWYPKLW 334
D YPK W
Sbjct: 240 DIYPKAW 246
>emb|CAC12368.1| (AL445067) dyskerin (nucleolar protein Nap57) related protein
[Thermoplasma acidophilum]
Length = 355
Score = 210 bits (528), Expect = 3e-53
Identities = 115/278 (41%), Positives = 169/278 (60%), Gaps = 6/278 (2%)
Query: 51 LDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEY 110
LDKP GPTSH+V W++ IL +EK H GTLDP V+GVL +A+ +A R+V + + KEY
Sbjct: 2 LDKPQGPTSHQVDHWVREILGIEKVAHIGTLDPNVTGVLTMAIGKAVRLVDVVHESPKEY 61
Query: 111 VALMHLHGDVPEDKIRAVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLF 170
V +M + D+ E+++R K+F G I Q PP+RSAV R LR + VY +++LE R VLF
Sbjct: 62 VGVMRFYEDITEEEVRYYFKKFTGRIYQLPPVRSAVARSLRIKTVYSLDLLEKKDRLVLF 121
Query: 171 RVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKED 230
V E+GTYIR+L IG G G M +LRRT +GPF ED +TL D ++
Sbjct: 122 HVKCESGTYIRTLCTDIGYVSGKGGQMVDLRRTSTGPFSEDR-CITLQDFAAMVELARK- 179
Query: 231 GIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIM 290
G ++ +R I M A + PKI +K SA+ +AHG++L GI ++ +KG+ VA++
Sbjct: 180 GEDKLLRDHILDMTYAFKDYPKIVVKRSAMRNIAHGSDLYAGGIKIIDGKFRKGERVAVI 239
Query: 291 TLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRD 328
+ ++LV G AM S+ + + VD + +F+ D
Sbjct: 240 SEDNDLVGTGIAMCSSDNIFMK----VVDFDHIFLEAD 273
>pir||A72325 tRNA-pseudouridine synthase (EC 5.4.99.-) TM0856 - Thermotoga
maritima (strain MSB8)
>gi|4981390|gb|AAD35938.1|AE001752_5 (AE001752) tRNA
pseudouridine 55 synthase [Thermotoga maritima]
Length = 309
Score = 133 bits (332), Expect = 2e-30
Identities = 102/323 (31%), Positives = 154/323 (47%), Gaps = 53/323 (16%)
Query: 44 IQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQAL 103
+++G++ KP GPTSH+VV +++ L K GHGGTLDP GVL + + + TR+++
Sbjct: 1 MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFY 60
Query: 104 LPAGKEYVALMHL-----------------HGDVPEDKIRAVMKEFEGEIIQRPPLRSAV 146
K Y M L +V E++IR + F GE Q PP SA
Sbjct: 61 KDLKKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVGEYDQVPPAYSAK 120
Query: 147 K---RRL--------------RTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGL 189
K RL + K++ I + I+GRDV FRV V GTYIRSL IG
Sbjct: 121 KYKGERLYKLAREGKIINLPPKRVKIFKIWDVNIEGRDVSFRVEVSPGTYIRSLCMDIGY 180
Query: 190 ALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEH 249
LG GA EL R GP +E+L + E I I P+EK +E
Sbjct: 181 KLGCGATAVELVRESVGPHTIEESLNVF------------EAAPEEIENRIIPLEKCLEW 228
Query: 250 LPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKA-----MM 304
LP++ + + + +G+ + + ++K G KKG++V + + L+AL +A +
Sbjct: 229 LPRVVVHQESTKMILNGSQIHLE-MLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFL 287
Query: 305 STQEMIERSKGIAVDVEKVFMPR 327
T ER++ + + + KVF R
Sbjct: 288 ETLRKHERNERV-LTLRKVFNTR 309
>pir||C82298 tRNA pseudouridine 55 synthase VC0645 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9655081|gb|AAF93811.1|
(AE004150) tRNA pseudouridine 55 synthase [Vibrio
cholerae]
Length = 312
Score = 123 bits (307), Expect = 2e-27
Identities = 89/279 (31%), Positives = 136/279 (47%), Gaps = 42/279 (15%)
Query: 46 YGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLP 105
+GVI LDKP G +S++ + +KR+ EKAGH G LDP +G+LP+ L AT+ Q LL
Sbjct: 11 HGVILLDKPTGISSNDALQKVKRLYGAEKAGHTGALDPLATGMLPICLGEATKFSQFLLD 70
Query: 106 AGKEYVALMHL---------HGDVPE--------DKIRAVMKEFEGEIIQRPPLRSAVK- 147
+ K Y + L G V + D + A + +F GE Q P + SA+K
Sbjct: 71 SDKRYRVIAKLGERTDTSDSDGQVVQTRPVHVDYDTLLACIAKFRGETDQVPSMFSALKY 130
Query: 148 ----------------RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLAL 191
R R VY IE+ +G +V V GTYIR+++ +G L
Sbjct: 131 QGRPLYEYARQGIEVPREARKITVYEIELHRFEGDEVEMEVHCSKGTYIRTIVDDLGEML 190
Query: 192 GVGAHMAELRR--TRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEH 249
G GAH+ LRR + P++ TL L+ LV+ H E + + + + PM+ AVE
Sbjct: 191 GCGAHVTMLRRVGVANYPYERMVTLEQLNALVEQAH-RDEKAVADVLDPLLLPMDTAVEA 249
Query: 250 LPKIWIKDSAVAAVAHGANLTV-----PGIVKLNAGIKK 283
LP++ + + + HG + V G+V++ G +K
Sbjct: 250 LPEVNVIPELMTLIQHGQAVQVSGAPSDGMVRITGGEQK 288
>sp|P32732|TRUB_BACSU TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE) >gi|7444626|pir||G69726 tRNA-pseudouridine
synthase (EC 5.4.99.-) - Bacillus subtilis
>gi|2634038|emb|CAB13539.1| (Z99112) tRNA pseudouridine
55 synthase [Bacillus subtilis]
Length = 309
Score = 119 bits (295), Expect = 5e-26
Identities = 96/295 (32%), Positives = 142/295 (47%), Gaps = 54/295 (18%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
GV+ L KP G TSH+ V I+++L +K GH GTLDP+VSGVLP+ + RAT++V+ L
Sbjct: 4 GVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSGVLPICVGRATKIVEYLTEK 63
Query: 107 GKEYVALMHL-------------------HGDVPEDKIRAVMKEFEGEIIQRPPLRSAVK 147
K Y A + L + D+ + + V+ +G+ Q PP+ SAVK
Sbjct: 64 SKTYDAEITLGFSTTTEDQTGETVETKPVNHDIDKADVEKVLNSLKGKQEQIPPMYSAVK 123
Query: 148 ---RRL-----------RTRKVYYIEILEI------DGRDVLFR--VGVEAGTYIRSLIH 185
++L R +++ IE + + G FR V GTY+R+L
Sbjct: 124 VNGKKLYEYARAGIEVERPKRMITIEDIALTTEIKHHGETASFRFTVTCSKGTYVRTLAV 183
Query: 186 HIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDG-IEEYIRKAIQPME 244
IG LG AHM+ L RT SG F DE D + G +EE+ P+E
Sbjct: 184 MIGEKLGYPAHMSHLIRTASGDFSLDECFT-----FDELEAQAQSGTVEEH----TVPIE 234
Query: 245 KAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVAL 299
+A+ HLPK I D+ V +GA L P + + + GD +A+ T +A+
Sbjct: 235 RALNHLPKWIISDTLAKKVENGALLETP---EQFSEMTSGDRIAVFTESGTCLAI 286
>pir||E83052 tRNA pseudouridine 55 synthase PA4742 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951004|gb|AAG08128.1|AE004888_3 (AE004888) tRNA
pseudouridine 55 synthase [Pseudomonas aeruginosa]
Length = 304
Score = 117 bits (290), Expect = 2e-25
Identities = 78/260 (30%), Positives = 125/260 (48%), Gaps = 39/260 (15%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G++ LDKP G +S++ + ++ +LN EKAGH G+LDP +GVLP+ AT+ Q LL A
Sbjct: 13 GILVLDKPRGMSSNQALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLDA 72
Query: 107 GKEYVALMHL-----HGD------------VPEDKIRAVMKEFEGEIIQRPPLRSAVK-- 147
K Y +M + GD V D + + F G+I Q PP+ SA+K
Sbjct: 73 DKGYETVMRMGITTTTGDAEGELLAERDVTVGRDDLEQALPRFRGDIEQVPPMYSALKKD 132
Query: 148 ---------------RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALG 192
R R+ + +++L + V GTY+R+L+ +G LG
Sbjct: 133 GQPLYKLARAGEVVEREARSVTITRLDLLSFEPPCATLAVSCSKGTYVRTLVEDLGQVLG 192
Query: 193 VGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPK 252
GAH+A LRRT++GPF + +TL L + +G E + + + P + + H P
Sbjct: 193 CGAHVAALRRTQAGPFALAQA-ITLETLERVH----AEGGPEALDQFLMPEDSGLLHWPV 247
Query: 253 IWIKDSAVAAVAHGANLTVP 272
+ + + + HG + P
Sbjct: 248 LQLSEHSAYYWLHGQPVRAP 267
>dbj|BAB06129.1| (AP001515) tRNA pseudouridine 5S synthase [Bacillus halodurans]
Length = 304
Score = 112 bits (278), Expect = 5e-24
Identities = 88/265 (33%), Positives = 126/265 (47%), Gaps = 51/265 (19%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G++ L KP G TSH+ VA ++R+L +K GH GTLDP V GVLPV + AT+V Q +
Sbjct: 5 GILPLAKPRGMTSHDCVAKLRRLLKTKKVGHTGTLDPDVYGVLPVCIGHATKVAQYMSDY 64
Query: 107 GKEYVALMHL---------HGDVPEDK----------IRAVMKEFEGEIIQRPPLRSAVK 147
K Y + + GD E K + V+ F GEI Q PP+ SAVK
Sbjct: 65 PKAYEGEVTVGFSTTTEDRSGDTVETKTIQQPFVEAVVDQVLATFVGEIKQIPPMYSAVK 124
Query: 148 -----------------RRLRTRKVYYIE-----ILEIDGRDVLFRVGVEAGTYIRSLIH 185
R RT ++ +E + E F V GTY+R+L
Sbjct: 125 VRGKRLYEYARAGITVERPERTVTIFSLERMSDIVYEEGVCRFRFNVSCSKGTYVRTLAV 184
Query: 186 HIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKA-IQPME 244
IG ALG AHM++L RT+SGPF +E T +L E+ +E+ + + P+E
Sbjct: 185 DIGKALGYPAHMSDLVRTKSGPFSLEECF-TFTEL--------EERLEQGEGSSLLLPIE 235
Query: 245 KAVEHLPKIWIKDSAVAAVAHGANL 269
A+ +P++ + + HGA L
Sbjct: 236 TAILDIPRVQVNKEIEEKIRHGAVL 260
>sp|O33335|TRUB_MYCTU TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE) >gi|7444632|pir||H70884 probable tRNA
modification enzyme - Mycobacterium tuberculosis (strain
H37RV) >gi|2624315|emb|CAA15588.1| (AL008967) truB
[Mycobacterium tuberculosis]
Length = 298
Score = 110 bits (273), Expect = 2e-23
Identities = 79/215 (36%), Positives = 108/215 (49%), Gaps = 40/215 (18%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G++ +DKP G TSH+VV +RI + GH GTLDP +GVL + +ERAT+++ L A
Sbjct: 7 GIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDPMATGVLVIGIERATKILGLLTAA 66
Query: 107 GKEYVALMHL---------HGDVPE---------DKIRAVMKEFEGEIIQRPPLRSAVK- 147
K Y A + L G V + + I A M+ GEI Q P SA+K
Sbjct: 67 PKSYAATIRLGQTTSTEDAEGQVLQSVPAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKV 126
Query: 148 --RR--------------LRTRKVYYIEILEIDGRDVLFRVGVE----AGTYIRSLIHHI 187
RR R ++ E+L RD L + VE +GTYIR+L +
Sbjct: 127 GGRRAYRLARQGRSVQLEARPIRIDRFELLAARRRDQLIDIDVEIDCSSGTYIRALARDL 186
Query: 188 GLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVD 222
G ALGVG H+ LRRTR G F+ D+ +L DL +
Sbjct: 187 GDALGVGGHVTALRRTRVGRFELDQAR-SLDDLAE 220
>emb|CAB36580.1| (AL035472) possible tRNA pseudouridine synthase B [Mycobacterium
leprae]
Length = 320
Score = 106 bits (263), Expect = 3e-22
Identities = 87/293 (29%), Positives = 131/293 (44%), Gaps = 58/293 (19%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G++ +DKP G TSH+VVA +RI + GH GTLDP +GVL + ++RAT+++ L A
Sbjct: 13 GIVVIDKPSGMTSHDVVARCRRIFCTRRVGHAGTLDPMATGVLVLGVDRATKILGLLAGA 72
Query: 107 GKEYVALMHL---------HGD---------VPEDKIRAVMKEFEGEIIQRPPLRSAVK- 147
KEYVA + L G+ V ++ I + G+I Q P SA+K
Sbjct: 73 SKEYVATIRLGQTTSTEDAEGELLQCVSARHVTDEAIATAIGRLRGDIKQVPSAVSAIKV 132
Query: 148 ----------------RRLRTRKVYYIEILEI---------DGRDVLFRVGVEAGTYIRS 182
+ R ++ E+L + D D+ V +GTYIR+
Sbjct: 133 DGRRAYRLVREGHVVELQARPVRIDRFEVLAVRPGPEVGLADVIDLDVEVECSSGTYIRA 192
Query: 183 LIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQP 242
L +G A GVG H+ LRRTR G F+ D+ W + + E R +
Sbjct: 193 LARDLGDAFGVGGHLTSLRRTRVGRFELDQA-------------WSLEDLAELPRLSRTL 239
Query: 243 MEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDE 295
E + P+ + S V A ++G ++ GI + A D I L+DE
Sbjct: 240 DETCLLMFPRRDLTVSEVEATSNGRPISSAGIDGIYAA-SDADGRVIALLRDE 291
>sp|O66922|TRUB_AQUAE TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE) >gi|7444631|pir||F70361 tRNA-pseudouridine
synthase (EC 5.4.99.-) truB - Aquifex aeolicus
>gi|2983293|gb|AAC06885.1| (AE000703) tRNA pseudouridine
55 synthase [Aquifex aeolicus]
Length = 287
Score = 106 bits (261), Expect = 5e-22
Identities = 82/272 (30%), Positives = 126/272 (46%), Gaps = 52/272 (19%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G + +DKP G TS EVV +K L KAGH GTLDP +G+L + + +ATR Q +
Sbjct: 3 GALLIDKPKGITSTEVVERVKEKLKARKAGHTGTLDPIATGLLIILINKATRFSQFFIGM 62
Query: 107 GKEY-----------------VALMHLHGDVPEDKIRAVMKEFEGEIIQRPPLRSAVKRR 149
K Y + G++ DK++ V+ EF GEI+Q PP SA K +
Sbjct: 63 PKTYRFTVKFGAETDTYDAQGKVVETYEGELNCDKLKEVLNEFRGEILQTPPPFSAKKIK 122
Query: 150 LR-----TRK------------VYYIEILEIDGR--DVLFRVGVEAGTYIRSLIHHIGLA 190
R RK VY +E+L + R + F + +G Y+RSL + IG
Sbjct: 123 GRRAYELARKGKKVELKPVKITVYSLELLSCNPREKEAEFLAEISSGGYVRSLAYDIGKK 182
Query: 191 LGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHL 250
LG+G +M ELRR K DE +++ + V F + EEY + P++ +
Sbjct: 183 LGIGGYMKELRR-----LKIDE--ISVEEAVSLEEFLSSENPEEY----VLPVDTLFRVI 231
Query: 251 PKIWIKDSAVAAVAHGANLTV-----PGIVKL 277
P++ + + G + + G+VK+
Sbjct: 232 PEVRLNTFEAGKILQGKRILIKNYDYEGLVKI 263
>sp|P09171|TRUB_ECOLI TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE) (P35 PROTEIN) >gi|76181|pir||Q9EC35
tRNA-pseudouridine synthase (EC 5.4.99.-) truB
[validated] - Escherichia coli >gi|42219|emb|CAA32021.1|
(X13775) P35 gene product (AA 1 - 314) [Escherichia
coli] >gi|42223|emb|CAA31635.1| (X13270) P35 gene
product (AA 1 - 314) [Escherichia coli]
>gi|2367200|gb|AAC76200.1| (AE000397) tRNA pseudouridine
5S synthase [Escherichia coli K12]
Length = 314
Score = 103 bits (254), Expect = 3e-21
Identities = 79/290 (27%), Positives = 132/290 (45%), Gaps = 43/290 (14%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
GV+ LDKP G +S++ + +KRI N +AGH G LDP +G+LP+ L AT+ Q LL +
Sbjct: 13 GVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDS 72
Query: 107 GKEYVALMHL---------HGDVPEDK--------IRAVMKEFEGEIIQRPPLRSAVK-- 147
K Y + L G + E++ + A + F G+I Q P + SA+K
Sbjct: 73 DKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQ 132
Query: 148 ---------------RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALG 192
R R VY + + +G ++ + GTYIR++I +G LG
Sbjct: 133 GKKLYEYARQGIEVPREARPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLG 192
Query: 193 VGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGI--EEYIRKAIQPMEKAVEHL 250
GAH+ LRR + E +VTL L + ++ I E + + PM+
Sbjct: 193 CGAHVIYLRRLAVSKYPV-ERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDY 251
Query: 251 PKIWIKDSAVAAVAHG-----ANLTVPGIVKLNAGIKKGDLVAIMTLKDE 295
P + + ++ +G + + G+V++ G + G + + + DE
Sbjct: 252 PVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEG-ENGKFIGMGEIDDE 300
>sp|P74696|TRUB_SYNY3 TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE) >gi|7444625|pir||S76902 tRNA-pseudouridine
synthase (EC 5.4.99.-) - Synechocystis sp. (strain PCC
6803) >gi|1653904|dbj|BAA18814.1| (D90917) tRNA
pseudouridine 55 synthase [Synechocystis sp.]
Length = 296
Score = 102 bits (253), Expect = 4e-21
Identities = 87/269 (32%), Positives = 129/269 (47%), Gaps = 52/269 (19%)
Query: 46 YGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLP 105
+G +NL KP TSH+ VA ++R+L ++ GHGGTLDP GVLP+A+ ATR++ LP
Sbjct: 2 FGFLNLHKPLHLTSHDCVAKVRRLLRQKRVGHGGTLDPLAEGVLPLAVGSATRLL-PYLP 60
Query: 106 AGKEYVALMH---------LHGDVPEDK---------IRAVMKEFEGEIIQRPPLRSAVK 147
K+Y AL+ L G+V E K + ++ F GEI Q PP SA++
Sbjct: 61 GAKQYQALIRFGVRTDSDDLAGEVLESKNVSYLTLAAVEQILPTFLGEIEQIPPQYSAIQ 120
Query: 148 ---RRLR-----------TRKVYYIEILEIDG------RDVLFRVGVEAGTYIRSLIHHI 187
+RL ++ I L+I G ++ +V GTYIR+L +
Sbjct: 121 VNGKRLYELARAGIPQAVPSRMVTINDLKILGWRSGNQPELDLQVTCGEGTYIRALARDL 180
Query: 188 GLALGVGAHMAELRRTRSGPFKEDET--LVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEK 245
G LG GA +A L R +SG D + L L +V EE+I + P ++
Sbjct: 181 GDRLGTGATLAGLVRQQSGGMALDNSVGLTALEKIV---------AEEEHI--PLIPPQE 229
Query: 246 AVEHLPKIWIKDSAVAAVAHGANLTVPGI 274
A+ HLP + + HG L +P +
Sbjct: 230 ALSHLPTVQLNSELEKRWFHGQRLLLPDL 258
>sp|P45142|TRUB_HAEIN TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE) >gi|1074717|pir||B64170 tRNA-pseudouridine
synthase (EC 5.4.99.-) HI1289 - Haemophilus influenzae
(strain Rd KW20) >gi|1574748|gb|AAC22938.1| (U32809)
tRNA pseudouridine 55 synthase (truB) [Haemophilus
influenzae Rd]
Length = 312
Score = 102 bits (252), Expect = 6e-21
Identities = 73/270 (27%), Positives = 119/270 (44%), Gaps = 39/270 (14%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
GV LDKP G +S++++ +KR+ KAGH G LDP +G+LP+ L AT+ Q LL A
Sbjct: 13 GVFLLDKPQGMSSNDIMQKVKRLFQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDA 72
Query: 107 GKEYVALMHL---------HGDVPE--------DKIRAVMKEFEGEIIQRPPLRSAVK-- 147
K Y+ L G V E +I +++F G+I+Q P + SA+K
Sbjct: 73 DKRYLVTAKLGERTDTSDAEGQVVETREVNLETQQILTALEQFRGDILQVPTMFSALKHN 132
Query: 148 ---------------RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALG 192
R R ++ + +E + + V GTYIR+L+ +G LG
Sbjct: 133 GKPLYEYARQGITVEREARPITIFELNFIEYNAPFLTLEVHCSKGTYIRTLVDDLGEVLG 192
Query: 193 VGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPK 252
GAH+ LRRT + E + ++ E + + + P + AV LP
Sbjct: 193 CGAHVTMLRRTAVADYPVAEMMP-----INELQLLAESFPLSELDRLLLPTDTAVSKLPA 247
Query: 253 IWIKDSAVAAVAHGANLTVPGIVKLNAGIK 282
+ + A+ G + +L+ ++
Sbjct: 248 LHLDAEQSKAIGFGQRVKFANEQQLSGQVR 277
>pir||C81091 tRNA pseudouridine synthase B NMB1374 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226620|gb|AAF41748.1| (AE002485) tRNA pseudouridine
synthase B [Neisseria meningitidis MC58]
Length = 307
Score = 101 bits (250), Expect = 1e-20
Identities = 80/262 (30%), Positives = 114/262 (42%), Gaps = 52/262 (19%)
Query: 35 PDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALE 94
P KR + GV+ LDKP G +S+ + +R+ + EKAGH G LDP +G+LPV
Sbjct: 6 PQKRAVN-----GVLLLDKPEGLSSNTALQKARRLFHAEKAGHTGVLDPLATGLLPVCFG 60
Query: 95 RATRVVQALLPAGKEYVALMHL-----------------HGDVPEDKIRAVMKEFEGEII 137
AT+ Q LL A K Y A + L D+ + + + G I
Sbjct: 61 EATKFAQYLLDADKAYTATLKLGEASSTGDAEGEIIATARADISLAEFQTACQALTGNIR 120
Query: 138 QRPPLRSAVK-----------------RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYI 180
Q PP+ SA+K R+ R VY I+I E D + V GTYI
Sbjct: 121 QVPPMFSALKHEGKPLYEYARKGIVIERKARYITVYAIDIAEFDAPKAVIDVRCSKGTYI 180
Query: 181 RSLIHHIGLALGVGAHMAELRRTRSGPF--KEDETLVTLHDLVDYYHFWKEDGIEEYIRK 238
R+L I +G AH+ LRRT + F + TL L +L + + D +
Sbjct: 181 RTLSEDIAKHIGTFAHLTALRRTETAGFTIAQSHTLEALANLNE----TERDSL------ 230
Query: 239 AIQPMEKAVEHLPKIWIKDSAV 260
+ P + V H P+ + D AV
Sbjct: 231 -LLPCDVLVSHFPQTVLNDYAV 251
>gb|AAA57969.1| (U18997) P35 [Escherichia coli]
Length = 314
Score = 101 bits (248), Expect = 2e-20
Identities = 78/290 (26%), Positives = 131/290 (44%), Gaps = 43/290 (14%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
GV+ LDKP G +S++ + +KRI N +AGH G LDP +G+LP+ L AT+ Q LL +
Sbjct: 13 GVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDS 72
Query: 107 GKEYVALMHL---------HGDVPEDK--------IRAVMKEFEGEIIQRPPLRSAVK-- 147
K Y + L G + E++ + A + F G+I Q P + SA+K
Sbjct: 73 DKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQ 132
Query: 148 ---------------RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALG 192
R VY + + +G ++ + GTYIR++I +G LG
Sbjct: 133 GKKLYEYARQGIEVPREAXPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLG 192
Query: 193 VGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGI--EEYIRKAIQPMEKAVEHL 250
GAH+ LRR + E +VTL L + ++ I E + + PM+
Sbjct: 193 CGAHVIYLRRLAVSKYPV-ERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDY 251
Query: 251 PKIWIKDSAVAAVAHG-----ANLTVPGIVKLNAGIKKGDLVAIMTLKDE 295
P + + ++ +G + + G+V++ G + G + + + DE
Sbjct: 252 PVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEG-ENGKFIGMGEIDDE 300
>pir||H72093 tRNA pseudouridine synthase B CP0438 [imported] - Chlamydophila
pneumoniae (strains CWL029 and AR39)
>gi|4376596|gb|AAD18468.1| (AE001616) tRNA Pseudouridine
Synthase [Chlamydophila pneumoniae CWL029]
>gi|7189361|gb|AAF38278.1| (AE002205) tRNA pseudouridine
synthase B [Chlamydophila pneumoniae AR39]
>gi|8978693|dbj|BAA98529.1| (AP002546) tRNA
pseudouridine synthase [Chlamydophila pneumoniae J138]
Length = 235
Score = 100 bits (247), Expect = 2e-20
Identities = 71/236 (30%), Positives = 122/236 (51%), Gaps = 44/236 (18%)
Query: 40 IELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERA-TR 98
+ + ++ G++ +DKP G TS ++ + +++ ++K GH GTLDP +GV+ + + R TR
Sbjct: 3 LAVELKEGILLVDKPQGRTSFSLIRALTKLIGVKKIGHAGTLDPFATGVMVMLIGRKFTR 62
Query: 99 VVQALLPAGKEYVALMHL----------------HGDVPE-DKIRAVMKEFEGEIIQRPP 141
+ LL KEY A+ HL +P +++ + + F+GEI Q PP
Sbjct: 63 LSDILLFEDKEYEAIAHLGTTTDSYDCDGKVVGRSKKIPSLEEVLSAAEYFQGEIQQLPP 122
Query: 142 LRSAVKRRLRTRKVY------------------YIEILEIDGRDVLFRVGVEAGTYIRSL 183
+ SA ++++ +K+Y +++I + + + F V GTYIRS+
Sbjct: 123 MFSA--KKVQGKKLYEYARKGLSIERHHSTVQVHLQITKYEYPLLHFVVSCSKGTYIRSI 180
Query: 184 IHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKA 239
H +G LG GA++ +LRR RSG F DE + +L+D+ F I Y+R A
Sbjct: 181 AHELGTMLGCGAYLEQLRRLRSGRFSIDECID--GNLLDHPDF----DISPYLRDA 230
>pir||T35986 probable tRNA pseudouridine synthase - Streptomyces coelicolor
>gi|4464271|emb|CAB37474.1| (AL035559) probable tRNA
pseudouridine synthase [Streptomyces coelicolor A3(2)]
Length = 301
Score = 100 bits (247), Expect = 2e-20
Identities = 70/209 (33%), Positives = 104/209 (49%), Gaps = 44/209 (21%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G++ +DKP G TSH+VVA ++ I + GH GTLDP +GVL + +ERAT+++ L
Sbjct: 10 GLVIVDKPSGFTSHDVVAKMRGIARTRRVGHAGTLDPMATGVLVLGVERATKLLGHLALT 69
Query: 107 GKEYVALMHL---------HGDVPEDK---------IRAVMKEFEGEIIQRPPLRSAVK- 147
KEY+ + L G++ + I A + E G+I+Q P SA+K
Sbjct: 70 EKEYLGTIRLGQTTLTDDAEGEITGSRDASKVTWEAIDAGVAELSGDIMQVPSKVSAIKI 129
Query: 148 ------RRLRTRKVYYI----------------EILEIDGR---DVLFRVGVEAGTYIRS 182
+R R + + I + + DG D++ V +GTYIR+
Sbjct: 130 KGVRSYKRAREGEEFEIPARPVTVSSFAVYDVRDAVADDGTPVLDLVVSVTCSSGTYIRA 189
Query: 183 LIHHIGLALGVGAHMAELRRTRSGPFKED 211
L +G LGVG H+ LRRTR GP+K D
Sbjct: 190 LARDLGAGLGVGGHLTALRRTRVGPYKLD 218
>pir||G81851 pseudouridylate synthase (EC 4.2.1.70) B tRNA-specific NMA1588
[imported] - Neisseria meningitidis (group A strain
Z2491) >gi|7380229|emb|CAB84815.1| (AL162756) tRNA
pseudouridine synthase B [Neisseria meningitidis Z2491]
Length = 306
Score = 100 bits (247), Expect = 2e-20
Identities = 79/262 (30%), Positives = 113/262 (42%), Gaps = 52/262 (19%)
Query: 35 PDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALE 94
P KRP+ GV+ LDKP G +S+ + + + EKAGH G LDP +G+LPV
Sbjct: 5 PAKRPVN-----GVLLLDKPEGLSSNTALQKTRHLFRAEKAGHTGVLDPLATGLLPVCFG 59
Query: 95 RATRVVQALLPAGKEYVALMHL-----------------HGDVPEDKIRAVMKEFEGEII 137
AT+ Q L+ A K Y A + L D+ + + + G I
Sbjct: 60 EATKFAQYLINADKAYTATLKLGEASSTGDAEGEIVATARADISLAEFQTACQALTGNIR 119
Query: 138 QRPPLRSAVK-----------------RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYI 180
Q PP+ SA+K R+ R VY I+I E D + V GTYI
Sbjct: 120 QVPPMFSALKHEGKPLYEYARKGIVIERKARDITVYAIDIAEFDAPKAVIDVRCSKGTYI 179
Query: 181 RSLIHHIGLALGVGAHMAELRRTRSGPF--KEDETLVTLHDLVDYYHFWKEDGIEEYIRK 238
R+L I +G AH+ LRRT + F + TL L +L + + D +
Sbjct: 180 RTLSEDIAKHIGTFAHLTALRRTETAGFTIAQSHTLEALANLDE----TERDSL------ 229
Query: 239 AIQPMEKAVEHLPKIWIKDSAV 260
+ P + V H P+ + D AV
Sbjct: 230 -LLPCDVLVAHFPQTVLNDYAV 250
>emb|CAA71695.1| (Y10692) yhbA [Yersinia enterocolitica]
Length = 317
Score = 99.5 bits (244), Expect = 5e-20
Identities = 79/290 (27%), Positives = 134/290 (45%), Gaps = 43/290 (14%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
GV+ LDKP G +S++V+ +KR+ + +AGH G LDP +G+LP+ L AT+ Q LL +
Sbjct: 21 GVLLLDKPLGLSSNDVLQKVKRLFSANRAGHTGALDPLATGMLPICLGEATKFSQFLLDS 80
Query: 107 GKEYVAL---------MHLHGDVPEDK--------IRAVMKEFEGEIIQRPPLRSAVK-- 147
K Y + H G + ++ A + G Q P + SA+K
Sbjct: 81 DKRYRVVARLGQRTNTSHAEGALISEREDICHTGTDDAALDSHRGSSQQVPSMYSALKHQ 140
Query: 148 ---------------RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALG 192
R R+ VY + + +G D+ + GTYIR++I +G LG
Sbjct: 141 GKPLYEYARQGIEVDREARSITVYELLFIRWEGNDLELEIHCSKGTYIRTIIDDLGELLG 200
Query: 193 VGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHF--WKEDGIEEYIRKAIQPMEKAVEHL 250
GAH++ LRR + + D +VTL L +E + + PM+ AV +
Sbjct: 201 CGAHVSYLRRLQVATYPSDR-MVTLEQLTAIVETAQAEERSPNAELDALLLPMDSAVLNF 259
Query: 251 PKIWIKDSAVAAVAHGANLTV-----PGIVKLNAGIKKGDLVAIMTLKDE 295
P++ + + A V G + V G+V++ G ++ + + I T+ ++
Sbjct: 260 PEVNLLPTVAAYVKQGQPVHVAGAPGEGMVRITEG-EERNFIGIGTIAED 308
>sp|O34273|TRUB_YEREN TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE)
Length = 309
Score = 99.5 bits (244), Expect = 5e-20
Identities = 79/290 (27%), Positives = 134/290 (45%), Gaps = 43/290 (14%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
GV+ LDKP G +S++V+ +KR+ + +AGH G LDP +G+LP+ L AT+ Q LL +
Sbjct: 13 GVLLLDKPLGLSSNDVLQKVKRLFSANRAGHTGALDPLATGMLPICLGEATKFSQFLLDS 72
Query: 107 GKEYVAL---------MHLHGDVPEDK--------IRAVMKEFEGEIIQRPPLRSAVK-- 147
K Y + H G + ++ A + G Q P + SA+K
Sbjct: 73 DKRYRVVARLGQRTNTSHAEGALISEREDICHTGTDDAALDSHRGSSQQVPSMYSALKHQ 132
Query: 148 ---------------RRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALG 192
R R+ VY + + +G D+ + GTYIR++I +G LG
Sbjct: 133 GKPLYEYARQGIEVDREARSITVYELLFIRWEGNDLELEIHCSKGTYIRTIIDDLGELLG 192
Query: 193 VGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHF--WKEDGIEEYIRKAIQPMEKAVEHL 250
GAH++ LRR + + D +VTL L +E + + PM+ AV +
Sbjct: 193 CGAHVSYLRRLQVATYPSDR-MVTLEQLTAIVETAQAEERSPNAELDALLLPMDSAVLNF 251
Query: 251 PKIWIKDSAVAAVAHGANLTV-----PGIVKLNAGIKKGDLVAIMTLKDE 295
P++ + + A V G + V G+V++ G ++ + + I T+ ++
Sbjct: 252 PEVNLLPTVAAYVKQGQPVHVAGAPGEGMVRITEG-EERNFIGIGTIAED 300
>gb|AAK40721.1| tRNA pseudouridine synthase subunit A (truB) [Sulfolobus
solfataricus]
Length = 89
Score = 97.1 bits (238), Expect = 3e-19
Identities = 42/69 (60%), Positives = 57/69 (81%), Gaps = 1/69 (1%)
Query: 15 KREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEK 74
K E ++ D +ET+ K+G+ P+KRPIE+HI+ +INLDKPPGPTSHEV W+K++LN+ K
Sbjct: 17 KNEWKIRKD-SETSDKYGYYPEKRPIEIHIKNSIINLDKPPGPTSHEVAYWVKKMLNVTK 75
Query: 75 AGHGGTLDP 83
AGHGGTL+P
Sbjct: 76 AGHGGTLEP 84
>pir||F71558 probable tRNA pseudouridine synthase - Chlamydia trachomatis
(serotype D, strain UW3/Cx) >gi|3328490|gb|AAC67685.1|
(AE001283) tRNA Pseudouridine Synthase [Chlamydia
trachomatis]
Length = 241
Score = 97.1 bits (238), Expect = 3e-19
Identities = 69/202 (34%), Positives = 99/202 (48%), Gaps = 34/202 (16%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERA-TRVVQALLP 105
GV+ +DKP G TS ++ + R++ ++K GH GTLDP +GV+ + + R TR+ +L
Sbjct: 10 GVLLVDKPQGRTSFSLIRSLVRLIGVKKIGHAGTLDPFATGVMVMLIGRKFTRLSDIMLF 69
Query: 106 AGKEYVALMHL----------------HGDVPE-DKIRAVMKEFEGEIIQRPPLRSAVKR 148
KEY A+ HL VP D++ F+GEI Q PP+ SA K
Sbjct: 70 EDKEYAAVAHLGTTTDTYDCDGKIVGRSKKVPTMDEVLTCTSYFQGEIQQVPPMFSAKKV 129
Query: 149 RLRTRKVYYIEILEIDGRDVL----------------FRVGVEAGTYIRSLIHHIGLALG 192
+ + Y + L I+ R F V GTYIRS+ H +G LG
Sbjct: 130 QGKKLYEYARQGLSIERRFATVTVNLRLVKYEYPRLHFVVQCSKGTYIRSIAHELGNMLG 189
Query: 193 VGAHMAELRRTRSGPFKEDETL 214
GA++ ELRR RSG F D+ +
Sbjct: 190 CGAYLEELRRLRSGSFSIDQCI 211
>pir||F81709 tRNA pseudouridine synthase B TC0369 [imported] - Chlamydia
muridarum (strain Nigg) >gi|7190410|gb|AAF39228.1|
(AE002304) tRNA pseudouridine synthase B [Chlamydia
muridarum]
Length = 241
Score = 94.4 bits (231), Expect = 2e-18
Identities = 67/204 (32%), Positives = 104/204 (50%), Gaps = 38/204 (18%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERA-TRVVQALLP 105
GV+ +DKP G TS ++ + R++ ++K GH GTLDP +GV+ + + R TR+ +L
Sbjct: 10 GVLLVDKPQGRTSFSLIRSLVRLIGVKKIGHAGTLDPFATGVMVMLIGRKFTRLSDIMLF 69
Query: 106 AGKEYVALMHLHGD----------VPEDKIRAVMKE-------FEGEIIQRPPLRSAVKR 148
KEY A+ HL V K M+E F+GEI Q PP+ SA +
Sbjct: 70 EDKEYSAVAHLGTTTDTYDCDGKIVGRSKKVPTMEEVLECTSYFQGEIQQVPPMFSA--K 127
Query: 149 RLRTRKVYY------------------IEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLA 190
+++ +K+Y + +++ + + F V GTYIRS+ H +G
Sbjct: 128 KVQGKKLYEYARQGLSIERSFATVRVDLRLIKYEYPRLHFVVKCSKGTYIRSIAHELGNM 187
Query: 191 LGVGAHMAELRRTRSGPFKEDETL 214
LG GA++ ELRR RSG F D+ +
Sbjct: 188 LGCGAYLEELRRLRSGNFSIDQCI 211
>sp|P57456|TRUB_BUCAI TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE) >gi|10039045|dbj|BAB13079.1| (AP001119) tRNA
pseudouridine 55 synthase [Buchnera sp. APS]
Length = 312
Score = 93.2 bits (228), Expect = 4e-18
Identities = 66/247 (26%), Positives = 116/247 (46%), Gaps = 39/247 (15%)
Query: 46 YGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLP 105
+G++ LDKP G +S+ + +K + + +KAG+ GTLDP +G+LP+ ++ L+
Sbjct: 10 HGLLLLDKPQGISSNNALQKVKMLFSAKKAGYIGTLDPLATGMLPICFGECSKFSHYLME 69
Query: 106 AGKEYVALMHLHGD------------------VPEDKIRAVMKEFEGEIIQRPPLRSA-- 145
+ K+Y + L G+ + KI++ +KE G I Q PP+ SA
Sbjct: 70 SNKKYHVIAKL-GEKTSTSDSDGIIIKKRPILINSFKIKSALKELTGLIEQIPPMYSAIK 128
Query: 146 ---------------VKRRLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLA 190
+KR +R ++ I + + + F++ GTY+R+L+ +G
Sbjct: 129 HNGVPLYKYARQGLNIKRSIRKVLIHDISSIHQEKNLIEFKIFCSKGTYVRTLVEDLGEK 188
Query: 191 LGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIE--EYIRKAIQPMEKAVE 248
LG GAH+ LRR + + LVT+ L K + E I + P++ V
Sbjct: 189 LGCGAHVIFLRRLEMASYLHSQ-LVTISYLHKLLRKEKNNNFNFFEKIDNLLMPIDSPVS 247
Query: 249 HLPKIWI 255
LPK+++
Sbjct: 248 FLPKVYL 254
>pir||D82831 tRNA pseudouridine synthase B XF0237 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9105048|gb|AAF83050.1|AE003877_5 (AE003877) tRNA
pseudouridine synthase B [Xylella fastidiosa]
Length = 302
Score = 91.3 bits (223), Expect = 1e-17
Identities = 62/198 (31%), Positives = 96/198 (48%), Gaps = 35/198 (17%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G++ LDKP G +S+ + +R+L +K GH G+LDP +G+LP+ AT++ LL +
Sbjct: 13 GILLLDKPAGISSNSALQIARRLLRAKKGGHTGSLDPLATGLLPLCFGEATKIAGLLLGS 72
Query: 107 GKEY------------------VALMHLHGDVPEDKIRAVMKEFEGEIIQRPPLRSAVKR 148
K Y V L + + + AV+ + G I QR P+ SA+K+
Sbjct: 73 TKAYDADVLLGTTTTTDDAEGAVLLTRPVPTLDAEMVDAVIPQLIGRIRQRAPIYSALKQ 132
Query: 149 -----------------RLRTRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLAL 191
+R +V+ IE+L + + RV +GTYIRSL+ +G L
Sbjct: 133 GGEPLYAKARRGEVVNAPVREVEVHAIELLVLATPRLQLRVTCGSGTYIRSLVRDLGEIL 192
Query: 192 GVGAHMAELRRTRSGPFK 209
G GAH+ LRR PF+
Sbjct: 193 GCGAHITALRRRWVAPFQ 210
>pir||E72696 probable nucleolar protein APE0989 - Aeropyrum pernix (strain
K1) >gi|5104658|dbj|BAA79973.1| (AP000060) 107aa long
hypothetical nucleolar protein [Aeropyrum pernix]
Length = 107
Score = 90.5 bits (221), Expect = 3e-17
Identities = 35/57 (61%), Positives = 52/57 (90%)
Query: 27 TNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDP 83
T+P++G+ P +RP++++++YG+I +DKPPGPTSHEVVAWIKR+L + +AGHGGTL+P
Sbjct: 37 TDPRYGYLPHERPLDVYLRYGMIVVDKPPGPTSHEVVAWIKRMLGVSRAGHGGTLEP 93
>pir||T44263 tRNA-pseudouridine 55 synthase (EC 5.4.99.-) [imported] -
Synechococcus sp. (strain PCC7942) (fragment)
>gi|4156224|dbj|BAA37097.1| (AB010691) tRNA pseudoridine
55 synthase [Synechococcus sp.]
Length = 153
Score = 88.5 bits (216), Expect = 1e-16
Identities = 52/119 (43%), Positives = 71/119 (58%), Gaps = 19/119 (15%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G +NLDKP G TSH+ VA ++R+L + GHGGTLDP V+GVLP+A+ RATR++ LP+
Sbjct: 5 GFVNLDKPAGWTSHDCVAKLRRLLRERRIGHGGTLDPAVTGVLPIAVGRATRLL-PYLPS 63
Query: 107 GKEYVALMH---------LHGD---------VPEDKIRAVMKEFEGEIIQRPPLRSAVK 147
GK YV + L GD + + I A + +F G I Q+PP SAV+
Sbjct: 64 GKTYVGTIRFGLQTSTDDLTGDRLAEADTSHLSREAIEAALPQFLGHIQQQPPQVSAVQ 122
>pir||T48619 tRNA synthase-like protein - Arabidopsis thaliana
>gi|7573471|emb|CAB87785.1| (AL163817) tRNA
synthase-like protein [Arabidopsis thaliana]
Length = 540
Score = 85.4 bits (208), Expect = 8e-16
Identities = 66/202 (32%), Positives = 98/202 (47%), Gaps = 37/202 (18%)
Query: 48 VINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAG 107
V+ ++KP G TS V ++R++ ++K GH GTLDP +G+L V + +AT+VV
Sbjct: 323 VLLVNKPKGWTSFTVCGKLRRLVKVKKVGHAGTLDPMATGLLIVCVGKATKVVDRYQGMI 382
Query: 108 KEYVALMH-------LHGDVP-----------EDKIRAVMKEFEGEIIQRPPLRSAVK-- 147
K Y + L D P +D I+ + F GEI Q PP+ SA+K
Sbjct: 383 KGYSGVFRLGEATSTLDADSPVIQRESWEHIKDDDIKKALTSFLGEIWQVPPMFSAIKVG 442
Query: 148 --------RR-----LRTRKV----YYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLA 190
RR L R++ + IE D ++++FRV GTYIRSL + A
Sbjct: 443 GEKMYEKARRGETVELSPRRISIFQFDIERSLDDRQNLIFRVICSKGTYIRSLCADLAKA 502
Query: 191 LGVGAHMAELRRTRSGPFKEDE 212
LG AH+ LRR G + ++
Sbjct: 503 LGSCAHLTALRRDSIGEYSAND 524
>gb|AAD50463.1|AF169967_6 (AF169967) TruB [Flavobacterium johnsoniae]
Length = 229
Score = 84.3 bits (205), Expect = 2e-15
Identities = 62/210 (29%), Positives = 98/210 (46%), Gaps = 42/210 (20%)
Query: 41 ELHIQYGVINLDKPPGPTSHEVVAWIKRILNLE-------KAGHGGTLDPKVSGVLPVAL 93
E +++ V+ +DKP +S + V +K +L + K GH GTLDP +G+L +
Sbjct: 4 EEYLEGQVLLIDKPLKWSSFQAVNKLKYLLINKVGLPKKFKIGHAGTLDPLATGLLLICT 63
Query: 94 ERATRVVQALLPAGKEYVALMHLHGDVP------------------EDKIRAVMKEFEGE 135
+ T+ + L KEY ++ P E I +K+F GE
Sbjct: 64 GKFTKKISELQGQAKEYTGTFYIGATTPSYDLETEIDQTFPTEHINEVLIHETVKQFLGE 123
Query: 136 IIQRPPLRSAVKR---------------RLRTRK--VYYIEILEIDGRDVLFRVGVEAGT 178
I Q+PP+ SA+K+ + +RK ++ EI I ++ FRV GT
Sbjct: 124 IDQKPPIFSAIKKDGVRLYEHARAGESIEIESRKTTIHEFEITRIALPEIDFRVVCSKGT 183
Query: 179 YIRSLIHHIGLALGVGAHMAELRRTRSGPF 208
YIRSL + G A+ G+H+ LRRT+ G +
Sbjct: 184 YIRSLAYDFGKAMNSGSHLTVLRRTKIGDY 213
>emb|CAA63512.1| (X92946) hypothetical protein [Lactococcus lactis]
Length = 177
Score = 82.7 bits (201), Expect = 6e-15
Identities = 51/120 (42%), Positives = 72/120 (59%), Gaps = 19/120 (15%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G++N+ K G TS +VVA ++ IL +K GHGGTLDP+V+GVLPVA+ +ATR+++ + A
Sbjct: 3 GILNVYKEAGWTSFDVVAKLRGILKTKKIGHGGTLDPQVTGVLPVAVGKATRLLEYMEEA 62
Query: 107 GKEYVALMHL---------HGDVPE----------DKIRAVMKEFEGEIIQRPPLRSAVK 147
GK Y + + G+V E ++I VM F GEI Q PP+ SAVK
Sbjct: 63 GKVYEGEVTIGFSTETEDAEGEVIETTPVPSTLSDEEIDEVMTRFVGEIQQVPPMYSAVK 122
>pir||B82902 tRNA pseudouridine 55 synthase UU354 [imported] - Ureaplasma
urealyticum >gi|6899334|gb|AAF30763.1|AE002132_7
(AE002132) tRNA pseudouridine 55 synthase [Ureaplasma
urealyticum]
Length = 227
Score = 76.9 bits (186), Expect = 3e-13
Identities = 56/219 (25%), Positives = 103/219 (46%), Gaps = 38/219 (17%)
Query: 44 IQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQAL 103
I +I ++KP TS++VV +KR++ +K GH GTLDP SGVL + + T+++ L
Sbjct: 4 ISKNIIIINKPIKWTSNDVVQKVKRVIGAKKVGHAGTLDPNASGVLVLGINEGTKLLTKL 63
Query: 104 LPAGKEYVA-----------------LMHLHGDVPEDKIRAVMKEF-EGEIIQRPPLRSA 145
+ K Y+A + + V ++ ++K+F + + Q+PP SA
Sbjct: 64 ILDNKSYIAEIKFGTSTNTYDAAGEIVSSTNRMVTLTEVTKIVKDFYKNDYWQKPPQFSA 123
Query: 146 VKRR-----------------LRTRKVYYIEILEIDGRDVLFRVG--VEAGTYIRSLIHH 186
+K R K++ +I++ + + ++ V G Y+RS
Sbjct: 124 LKINGQKAYVLARQKVDFEIAPRLVKIFKYQIMDFNYEKQILKISLHVSKGFYVRSFAVD 183
Query: 187 IGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYH 225
+ + AH+ L RT+SGPF E + + + + DY++
Sbjct: 184 LATKINNLAHLLTLIRTQSGPF-EIKDAIEIEQVYDYWN 221
>gb|AAB48163.1| (U54794) Orp [Pseudomonas aeruginosa]
Length = 139
Score = 75.7 bits (183), Expect = 7e-13
Identities = 44/119 (36%), Positives = 65/119 (53%), Gaps = 17/119 (14%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G++ LDKP G +S++ + ++ +LN EKAGH G+LDP +GVLP+ AT+ Q LL A
Sbjct: 13 GILVLDKPRGMSSNQALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLDA 72
Query: 107 GKEYVALMHL-----HGD------------VPEDKIRAVMKEFEGEIIQRPPLRSAVKR 148
K Y +M + GD V D + + F G+I Q PP+ SA+K+
Sbjct: 73 DKGYETVMRMGITTTTGDAEGELLAERDVTVGRDDLEQALPRFRGDIEQVPPMYSALKK 131
>sp|P72154|TRUB_PSEAE TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE) (ORP PROTEIN)
Length = 138
Score = 75.7 bits (183), Expect = 7e-13
Identities = 44/119 (36%), Positives = 65/119 (53%), Gaps = 17/119 (14%)
Query: 47 GVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPA 106
G++ LDKP G +S++ + ++ +LN EKAGH G+LDP +GVLP+ AT+ Q LL A
Sbjct: 13 GILVLDKPRGMSSNQALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLDA 72
Query: 107 GKEYVALMHL-----HGD------------VPEDKIRAVMKEFEGEIIQRPPLRSAVKR 148
K Y +M + GD V D + + F G+I Q PP+ SA+K+
Sbjct: 73 DKGYETVMRMGITTTTGDAEGELLAERDVTVGRDDLEQALPRFRGDIEQVPPMYSALKK 131
>sp|O51743|TRUB_BORBU TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE)
(PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL
HYDROLYASE) >gi|7444630|pir||B70200 tRNA-pseudouridine
synthase (EC 5.4.99.-) BB0803 - Lyme disease spirochete
>gi|2688745|gb|AAC67151.1| (AE001179) tRNA pseudouridine
55 synthase (truB) [Borrelia burgdorferi]
Length = 282
Score = 72.6 bits (175), Expect = 6e-12
Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 37/208 (17%)
Query: 44 IQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQAL 103
++ G + ++K G TS E + IK+ N + GH GTLD SG+L + + T++
Sbjct: 1 MENGFLLINKEQGKTSFETLFPIKKYFNTNRVGHAGTLDKFASGILVCLVGKYTKLSGYF 60
Query: 104 LPAGKEYVALMH--LHGDVPEDKIRAV---------------MKEFEGEIIQRPPLRSAV 146
KEYVA L D + R V +K+F GEI Q PP S+V
Sbjct: 61 TSLDKEYVAEFRFGLETDTLDPNGRIVSKTDYIPNVEDIDLKLKDFVGEIYQSPPRFSSV 120
Query: 147 -----------------KRRLRTRKVYYIEILEIDGRDVL--FRVGVEAGTYIRSLIHHI 187
+ + R VY I+ L D L ++ GTYIRS+ +
Sbjct: 121 HIDGSRAYKLALNGKFFEIKKRKVTVYNIQRLSYDFSSSLLSLKISCSKGTYIRSIARDL 180
Query: 188 GLALGVGAHMAELRRTRSGPFK-EDETL 214
+L A+++ L+RT+ G F+ +D TL
Sbjct: 181 AYSLNSCAYVSNLKRTKVGMFRLKDSTL 208
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.140 0.415
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 129820884
Number of Sequences: 2977
Number of extensions: 5648013
Number of successful extensions: 13896
Number of sequences better than 1.0e-10: 61
Number of HSP's better than 0.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 13755
Number of HSP's gapped (non-prelim): 61
length of query: 334
length of database: 189,106,746
effective HSP length: 54
effective length of query: 280
effective length of database: 156,788,448
effective search space: 43900765440
effective search space used: 43900765440
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)