BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0367 (eno-like) DE:enolase related (eno) (342 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||C75172 enolase related (eno) PAB0367 - Pyrococcus abyssi (s... 672 0.0 pir||F71042 hypothetical protein PH1630 - Pyrococcus horikoshii ... 594 e-169 sp|O26149|ENO_METTH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 143 2e-33 dbj|BAB07275.1| (AP001519) enolase (2-phosphoglycerate dehydrata... 109 3e-23 sp|O59605|ENO_PYRHO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 108 8e-23 sp|P33675|ENO_ZYMMO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 106 4e-22 pir||H75022 phosphopyruvate hydratase (EC 4.2.1.11) PAB1126 - Py... 106 4e-22 gb|AAD35958.1|AE001753_14 (AE001753) enolase [Thermotoga maritima] 101 1e-20 gi|11498732 enolase (eno) [Archaeoglobus fulgidus] >gi|6015092|s... 101 1e-20 sp|P42848|ENO_THEMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 101 1e-20 sp|O85348|ENO_NITEU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 99 5e-20 pir||D75251 enolase - Deinococcus radiodurans (strain R1) >gi|64... 99 7e-20 pir||A81841 phosphopyruvate hydratase (EC 4.2.1.11) NMA1495 [imp... 99 9e-20 pir||D81100 enolase NMB1285 [imported] - Neisseria meningitidis ... 99 9e-20 pir||A41835 phosphopyruvate hydratase (EC 4.2.1.11) - Bacillus s... 98 1e-19 sp|P37869|ENO_BACSU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 98 1e-19 sp|P29201|ENO_HALMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 97 3e-19 sp|P96377|ENO_MYCTU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 92 7e-18 pir||T33721 phosphopyruvate hydratase (EC 4.2.1.11) eno - Zymomo... 92 7e-18 dbj|BAA81815.1| (AB029313) enolase [Streptococcus intermedius] 92 1e-17 emb|CAC09537.1| (AL442120) enolase [Streptomyces coelicolor] 92 1e-17 sp|O66778|ENO_AQUAE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 92 1e-17 sp|Q60173|ENO_METJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 90 3e-17 sp|O69174|ENO_STAAU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 90 4e-17 sp|P48285|ENO_HELPY ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 90 4e-17 sp|Q9ZMS6|ENO_HELPJ ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 89 7e-17 sp|O30885|ENO_CAMFE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 86 5e-16 emb|CAC12011.1| (AL445065) enolase related protein [Thermoplasma... 85 1e-15 dbj|BAB07786.1| (AB046715) enolase [Desulfovibrio vulgaris] 85 1e-15 gb|AAF13454.1|AF205070_1 (AF205070) enolase [Mastigamoeba balamu... 84 2e-15 sp|Q57651|Y198_METJA HYPOTHETICAL PROTEIN MJ0198 >gi|2128174|pir... 84 2e-15 gb|AAC47644.1| (U85832) enolase [Stylochus zebra] 83 4e-15 gb|AAF73201.1|AF152348_1 (AF152348) enolase [Trypanosoma brucei ... 82 1e-14 sp|Q9Z7A6|ENO_CHLPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 82 1e-14 sp|P42448|ENO_CAMJE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 81 2e-14 sp|P08324|ENO_ECOLI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 80 4e-14 pir||E82076 enolase VC2447 [imported] - Vibrio cholerae (group O... 80 4e-14 emb|CAA57795.1| (X82400) enolase [Escherichia coli] 80 4e-14 emb|CAB94910.1| (AJ401152) enolase [Enterococcus faecalis] 80 5e-14 gb|AAC47645.1| (U85834) enolase [Tubularia sp.] 78 2e-13 sp|O84591|ENO_CHLTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 77 3e-13 pir||A72477 probable enolase APE2458 - Aeropyrum pernix (strain ... 76 4e-13 sp|Q27527|ENO_CAEEL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 76 7e-13 sp|P40370|ENO1_SCHPO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2... 75 9e-13 gb|AAC43380.1| (U13756) enolase [Helicobacter pylori] 75 9e-13 emb|CAB96125.1| (AJ272111) enolase [Euglena gracilis] 75 9e-13 gb|AAC47639.1| (U85833) enolase [Hymenolepis diminuta] 75 1e-12 sp|P15007|ENO_DROME ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 74 2e-12 gb|AAF51344.1| (AE003585) Eno gene product [Drosophila melanogas... 74 2e-12 sp|P74934|ENO_TREPA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 73 4e-12 sp|P07323|ENOG_RAT GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LY... 73 5e-12 emb|CAC16971.1| (AL450350) enolase [Streptomyces coelicolor] 73 5e-12 sp|P43806|ENO_HAEIN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 73 5e-12 sp|P08734|ENO_XENLA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 73 5e-12 sp|O52191|ENO_STRTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 73 5e-12 emb|CAB94039.1| (AL358652) enolase [Leishmania major] 72 8e-12 pir||S43113 phosphopyruvate hydratase (EC 4.2.1.11) - fungus (C... 72 1e-11 sp|P07322|ENOB_CHICK BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-L... 72 1e-11 sp|P42040|ENO_CLAHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 72 1e-11 pir||T39737 enolase - fission yeast (Schizosaccharomyces pombe) ... 71 1e-11 pir||JC1039 phosphopyruvate hydratase (EC 4.2.1.11) - rat 71 2e-11 gb|AAB87890.1| (AF025805) enolase [Drosophila pseudoobscura] 71 2e-11 gb|AAB87891.1| (AF025806) enolase [Drosophila subobscura] 71 2e-11 pir||A23850 phosphopyruvate hydratase (EC 4.2.1.11), skeletal mu... 71 2e-11 gb|AAD45339.1|AF159529_1 (AF159529) enolase [Trypanosoma brucei] 71 2e-11 gb|AAF36733.1| (AC016662) putative enolase; 31277-33713 [Arabido... 71 2e-11 emb|CAA31512.1| (X13120) neurone-specific enolase [Homo sapiens]... 70 3e-11 pir||E81654 enolase TC0876 [imported] - Chlamydia muridarum (str... 70 3e-11 sp|P09104|ENOG_HUMAN GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-... 70 3e-11 gi|7305027 enolase 2, gamma neuronal [Mus musculus] >gi|119348|s... 70 4e-11 gb|AAC47640.1| (U85826) enolase [Haematoloechus sp.] 70 4e-11 gb|AAC47641.1| (U85828) enolase [Lacistorhynchus tenuis] 70 4e-11 gb|AAC46289.1| (AF000366) enolase homolog [Borrelia burgdorferi] 70 4e-11 sp|O51312|ENO_BORBU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 70 4e-11 sp|P42894|ENO_NEOFR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 69 5e-11 gi|5803011 enolase 2, (gamma, neuronal); Enolase-2, gamma, neuro... 69 7e-11 sp|P30575|ENO1_CANAL ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) ... 69 9e-11 gi|6323985 Ymr323wp [Saccharomyces cerevisiae] >gi|1706698|sp|P4... 69 9e-11 gb|AAC47638.1| (U85827) enolase [Hydra cf. oligactis] 69 9e-11 sp|O57391|ENOG_CHICK GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-... 69 9e-11 >pir||C75172 enolase related (eno) PAB0367 - Pyrococcus abyssi (strain Orsay) >gi|5457968|emb|CAB49458.1| (AJ248284) enolase related (eno) [Pyrococcus abyssi] Length = 342 Score = 672 bits (1716), Expect = 0.0 Identities = 342/342 (100%), Positives = 342/342 (100%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEII 60 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEII Sbjct: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEII 60 Query: 61 GPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIG 120 GPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIG Sbjct: 61 GPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIG 120 Query: 121 GTFATELPVPIIQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKASE 180 GTFATELPVPIIQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKASE Sbjct: 121 GTFATELPVPIIQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKASE 180 Query: 181 SVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFIDG 240 SVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFIDG Sbjct: 181 SVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFIDG 240 Query: 241 EYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADDTFP 300 EYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADDTFP Sbjct: 241 EYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADDTFP 300 Query: 301 HLALGLRCPAMLISWNSVEKINELNRIAEELGERGRIITFEE 342 HLALGLRCPAMLISWNSVEKINELNRIAEELGERGRIITFEE Sbjct: 301 HLALGLRCPAMLISWNSVEKINELNRIAEELGERGRIITFEE 342 >pir||F71042 hypothetical protein PH1630 - Pyrococcus horikoshii >gi|3258059|dbj|BAA30742.1| (AP000006) 341aa long hypothetical protein [Pyrococcus horikoshii] Length = 341 Score = 594 bits (1515), Expect = e-169 Identities = 291/342 (85%), Positives = 322/342 (94%), Gaps = 1/342 (0%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEII 60 MSVIQNIIGR+ VLRGG YSVEVDVATDEGFGRF SPI++NPMLHIAEARRAVSEVDEII Sbjct: 1 MSVIQNIIGRIAVLRGGKYSVEVDVATDEGFGRFTSPIDDNPMLHIAEARRAVSEVDEII 60 Query: 61 GPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIG 120 GPELIGFDA EQELIDSYLWEIDGTEDFSHIGANTALAVS AIA+AAANS+DM LYSYIG Sbjct: 61 GPELIGFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSTAIAKAAANSRDMPLYSYIG 120 Query: 121 GTFATELPVPIIQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKASE 180 GTFATELPVP++ FA D+ F+YY++V+DLLEVTDI+DA NKI E+ ++++E LSKASE Sbjct: 121 GTFATELPVPVLSFAQDDMFDYYLVVKDLLEVTDIIDATNKI-REIVKEINLENLSKASE 179 Query: 181 SVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFIDG 240 VG+ELGLEVALGI MK+E++IE VLN+VED NVAYIKP+GPPELFLELIAGTHGVFIDG Sbjct: 180 DVGVELGLEVALGIGMKKEMDIEKVLNLVEDYNVAYIKPIGPPELFLELIAGTHGVFIDG 239 Query: 241 EYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADDTFP 300 EYLFR N++LDRRYYNALSIKPINLGTLTDLYNFVNDVK+EKITPILAEAKYEPAD+TFP Sbjct: 240 EYLFRTNSVLDRRYYNALSIKPINLGTLTDLYNFVNDVKAEKITPILAEAKYEPADETFP 299 Query: 301 HLALGLRCPAMLISWNSVEKINELNRIAEELGERGRIITFEE 342 H+ALGLRCPAMLISW+S+EKINELNRIAEELGERGRIITFEE Sbjct: 300 HIALGLRCPAMLISWSSIEKINELNRIAEELGERGRIITFEE 341 >sp|O26149|ENO_METTH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436881|pir||A69156 enolase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621078|gb|AAB84550.1| (AE000796) enolase [Methanobacterium thermoautotrophicum] Length = 416 Score = 143 bits (358), Expect = 2e-33 Identities = 129/405 (31%), Positives = 190/405 (46%), Gaps = 76/405 (18%) Query: 2 SVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPI------EENPMLHIAEARRAVSE 55 S+I+++ R ++ G +VEVDV T GFGR A+P E ++E Sbjct: 3 SIIEDVRVRKILDSRGNPTVEVDVITWNGFGRAAAPSGASTGSREVAAFPSGGVDEIITE 62 Query: 56 VDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSL 115 V++II ELIG DAV+ + ID L EIDGTE+ S +G NT +AVS+A A+AAA+S +M L Sbjct: 63 VEDIISSELIGMDAVDLQDIDLVLKEIDGTENLSSLGGNTVVAVSMATAKAAASSYNMPL 122 Query: 116 YSYIGGTFATELPVPIIQFASD--------ENFEYYILV----RDLLEVTDIVDAVNKII 163 Y ++GG AT +P P+ + + + +++V D+ E AV+K I Sbjct: 123 YRFLGGNLATSIPYPLGNMINGGAHAGKNAPDIQEFLVVPVGAEDITEAVFANAAVHKRI 182 Query: 164 SEV----------------------GNKVSIEELSKASESVGMELGLEVALGIKMKR--- 198 E+ N ++E + A E V ELG+EV + + Sbjct: 183 RELIQKKDPSFAGGKGDEGGWVPSLSNGDALEIQATACEEVTDELGVEVRPSLDLAASEF 242 Query: 199 ---ELE----------------IEDVLNIVEDNNVAYIK-PL--GPPELFLEL--IAGTH 234 E+E IE V I+E ++ Y++ PL G E F EL + G Sbjct: 243 WDPEIEKYVYRQENVQKDTGEQIEFVKEIIETYDMYYVEDPLHEGDLEGFAELTSLVGDR 302 Query: 235 GVFIDGEYLFRANNILDRRYY-----NALSIKPINLGTLTDLYNFVNDVKSEKITPILAE 289 I G+ +F N + R NA+ IKP +GTLTD Y V + TP+++ Sbjct: 303 -CMICGDDIFVTNREILREGIEMGAANAIIIKPNQIGTLTDTYLTVKLALENRYTPVVSH 361 Query: 290 AKYEPADDTFPHLALGLRCPAM---LISWNSVEKINELNRIAEEL 331 E DDT HLA+ P + I + K+NEL RI EE+ Sbjct: 362 RSGETTDDTIAHLAVAFGAPLIKTGAIGGERIAKLNELIRIQEEI 406 >dbj|BAB07275.1| (AP001519) enolase (2-phosphoglycerate dehydratase) [Bacillus halodurans] Length = 429 Score = 109 bits (271), Expect = 3e-23 Identities = 112/414 (27%), Positives = 185/414 (44%), Gaps = 83/414 (20%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51 M++I ++ R V+ G +VEV+V + G GR P + + A R Sbjct: 1 MTIITDVYAREVLDSRGNPTVEVEVYLESGAMGRALVPSGASTGEYEAVELRDGGERFLG 60 Query: 52 -----AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARA 106 AV V+E+I PELIGFDA++Q ID ++ E+DGTE+ +GAN L VS+A+ARA Sbjct: 61 KGVLKAVENVNEVIAPELIGFDALDQIGIDQHMIELDGTENKGKLGANAILGVSMAVARA 120 Query: 107 AANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLEV 152 AAN+ D+ LY Y+GG A +LPVP++ +D N E+ I+ ++ L Sbjct: 121 AANALDLPLYVYLGGFNAKQLPVPMMNIINGGEHADNNVDIQEFMIMPVGAESFKEALRT 180 Query: 153 -TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGI 194 T+I ++ K++ G N+ +++ + +A E G G +V L + Sbjct: 181 GTEIFHSLKKVLKSKGYNTAVGDEGGFAPNLSSNEEALQTIIEAIEQAGYTPGEQVKLAM 240 Query: 195 KM-----------KRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGT-------HGV 236 + K L E + + + VA+ + L + + G H + Sbjct: 241 DVASSELYNKEDGKYHLSGEGKV-LSSEEMVAFYEELVAKYPIISIEDGLDENDWEGHKM 299 Query: 237 FID---------GEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDVKSEK 282 D G+ LF N +++ N++ IK +GTLT+ ++ + K Sbjct: 300 LTDRLGDKVQLVGDDLFVTNTKKLAQGIEQGVGNSILIKVNQIGTLTETFDAIEMAKRAG 359 Query: 283 ITPILAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELG 332 T +++ E D T +A+ + S V K N+L RI +ELG Sbjct: 360 YTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELG 413 >sp|O59605|ENO_PYRHO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436873|pir||F71209 probable phosphoglycerate dehydratase - Pyrococcus horikoshii >gi|3258386|dbj|BAA31069.1| (AP000007) 428aa long hypothetical phosphoglycerate dehydratase [Pyrococcus horikoshii] Length = 428 Score = 108 bits (268), Expect = 8e-23 Identities = 116/407 (28%), Positives = 176/407 (42%), Gaps = 80/407 (19%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAE-------------AR 50 I I+ R ++ G +VEVDV T GR A P + H A R Sbjct: 7 ITAIVAREILDSRGNPTVEVDVHTPIAMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVR 66 Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 RAV V++II PELIG D Q ID L E+DGTE+ S++GAN LAVS+A+A+AAANS Sbjct: 67 RAVENVNKIIAPELIGMDVRWQREIDKLLIELDGTENKSNLGANAILAVSLAVAKAAANS 126 Query: 111 KDMSLYSYIGGTFATELPVPI-------IQFASDENFE---------------------- 141 ++ LY Y+GG A LPVP+ + ++ +F+ Sbjct: 127 LELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNELDFQEFMIMPIGASSFREAIRWVSET 186 Query: 142 YYILVRDLL---------------------EVTDIVDAVNKIISEVGNKVSIEELSKASE 180 Y++L R ++ EVT+ +DA+ K I E G K +E++ A + Sbjct: 187 YHVLKRVIMGKYGKNAVNVGDEGGFAPPMKEVTEPLDALIKAIEEAGYKPG-DEIALAID 245 Query: 181 SVGMEL---GLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTH--- 234 + E G + G + RE ++ +V + I+ E + + T+ Sbjct: 246 AASSEFFKDGKYIVGGKEYTREELLDLYKELVSTYPIVSIEDPFHEEDWEGFVMITNELG 305 Query: 235 -GVFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILA 288 + I G+ LF R ++ NAL +K +GTLT+ + + I++ Sbjct: 306 KKIQIVGDDLFVTNPRRLKKGIELGAANALLLKVNQIGTLTEAMDAAYTAFRAGYSVIVS 365 Query: 289 EAKYEPADDTFPHLALGLRCPAMLIS----WNSVEKINELNRIAEEL 331 E D T LA+ L + + K N+L RI EEL Sbjct: 366 HRSGETEDTTIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 412 >sp|P33675|ENO_ZYMMO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|538726|pir||A45732 phosphopyruvate hydratase (EC 4.2.1.11) - Zymomonas mobilis >gi|155581|gb|AAA27686.1| (M99380) enolase [Zymomonas mobilis] Length = 428 Score = 106 bits (262), Expect = 4e-22 Identities = 107/413 (25%), Positives = 181/413 (42%), Gaps = 81/413 (19%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51 M+ I +I GR VV G +VEVDV ++G FGR A P + +H A R Sbjct: 1 MTAIVSIHGRQVVDSRGNPTVEVDVTLEDGSFGRAAVPSGASTGVHEAVELRDGDKTRWG 60 Query: 52 ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 AV V+ I +IG +A +QELID + ++DGT + GAN L VS+A+A+ Sbjct: 61 GKGVTKAVHAVNNEIANAIIGLEAEDQELIDQTMIKLDGTPNKGKFGANAILGVSLAVAK 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFASDE-------NFEYYIL-------VRDLLE 151 AAA ++ + LY Y+GGT A LPVP++ + +F+ +++ + + + Sbjct: 121 AAAEARGLPLYRYVGGTAAHVLPVPMMNIVNGGMHADNPIDFQEFMIAPVGASSINEAVR 180 Query: 152 V-TDIVDAVNKIISEVGNKVS---------------------IEELSKASESVGME--LG 187 + T++ + K +S G + ++ +SKA G + + Sbjct: 181 IGTEVFHTLKKELSAKGMNTNVGDEGGFAPSLDSASSALDFIVDSISKAGYKPGEDVFIA 240 Query: 188 LEVALGIKMKRELEIEDV----------------LNIVEDNNVAYIKPLGPPEL-FLELI 230 L+ A ++ I D+ + + + I+ L + F +++ Sbjct: 241 LDAASSEFYNKDQNIYDLKGEGRKLTSAQLVDYYVELCGKYPIYSIEDLAEDDFEFWKIL 300 Query: 231 AGTHG--VFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKI 283 G V + G+ LF R ++ ++R N+L +K +G+L++ VN Sbjct: 301 TEKLGDKVQLVGDDLFVTNVKRLSDGIERGIANSLLVKFNQIGSLSETLAAVNMANDASY 360 Query: 284 TPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELG 332 TP+++ E D T LA+ C L + K N+L RI EELG Sbjct: 361 TPVMSHRSVETEDTTIADLAVATNCGQIKTGSLCRSERIAKYNQLMRIEEELG 413 >pir||H75022 phosphopyruvate hydratase (EC 4.2.1.11) PAB1126 - Pyrococcus abyssi (strain Orsay) >gi|5459136|emb|CAB50622.1| (AJ248288) enolase (EC 4.2.1.11) (eno) [Pyrococcus abyssi] Length = 430 Score = 106 bits (262), Expect = 4e-22 Identities = 88/259 (33%), Positives = 130/259 (49%), Gaps = 32/259 (12%) Query: 7 IIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAE-------------ARRAV 53 +I R ++ G +VEVDV T GR A P + H A RRAV Sbjct: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVRRAV 71 Query: 54 SEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDM 113 V++II PEL+G D Q ID L E+DGTE+ S++GAN LAVS+A+A+AAAN+ ++ Sbjct: 72 ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131 Query: 114 SLYSYIGGTFATELPVPI-------IQFASDENFEYYILVRDLLEVTDIVDAVNKIIS-- 164 LY Y+GG A LPVP+ + +D +F+ ++++ + +A+ + Sbjct: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMP--IGANSFREAIRWVSETY 189 Query: 165 EVGNKVSIEELSKASESVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPE 224 V KV E+ K + +VG E G MK E DVL ++ A KP E Sbjct: 190 HVLKKVIAEKYGKNAVNVGDEGG----FAPPMKEVTEPLDVL--IKAIEEAGYKP--GEE 241 Query: 225 LFLELIAGTHGVFIDGEYL 243 + L L A + + DG+Y+ Sbjct: 242 IALALDAASSEFYKDGKYI 260 >gb|AAD35958.1|AE001753_14 (AE001753) enolase [Thermotoga maritima] Length = 427 Score = 101 bits (249), Expect = 1e-20 Identities = 101/348 (29%), Positives = 156/348 (44%), Gaps = 65/348 (18%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 +AV V+E I P LIG +A +Q L+D L E+DGTE+ S +GAN LAVS+A+ARAAAN Sbjct: 65 KAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAAANY 124 Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLEV-TDI 155 + LY Y+GG A LPVP++ +D N E+ I+ R+ L +I Sbjct: 125 LGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAGAEI 184 Query: 156 VDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGIKMK- 197 + KI+ E G N+ +I+ L +A E G + G EV + + Sbjct: 185 FHTLKKILHEAGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIALDCAA 244 Query: 198 ---------------RELEIEDVLNIVEDNNVAY-IKPLGPP------ELFLELIAGT-H 234 E E ++ E+ Y I + P + F+E + Sbjct: 245 SSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFTKRVGN 304 Query: 235 GVFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAE 289 V I G+ L+ R + ++ + N++ IK +GT+T+ + V + +T I++ Sbjct: 305 KVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMTAIISH 364 Query: 290 AKYEPADDTFPHLAL----GLRCPAMLISWNSVEKINELNRIAEELGE 333 E D LA+ G L + K N+L RI EELG+ Sbjct: 365 RSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGK 412 >gi|11498732 enolase (eno) [Archaeoglobus fulgidus] >gi|6015092|sp|O29133|ENO_ARCFU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436882|pir||C69391 enolase (eno) homolog - Archaeoglobus fulgidus >gi|2649457|gb|AAB90112.1| (AE001026) enolase (eno) [Archaeoglobus fulgidus] Length = 366 Score = 101 bits (249), Expect = 1e-20 Identities = 90/344 (26%), Positives = 156/344 (45%), Gaps = 62/344 (18%) Query: 55 EVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMS 114 E++E + +IG +QE +D L E+DGT++FS IG N A+ S+A+A+AAA + Sbjct: 23 EIEEEVSKAIIGMSVFDQESVDEALRELDGTDNFSRIGGNFAITASLAVAKAAAEILGLP 82 Query: 115 LYSYIGGTFATELPVPIIQF--------ASDENFEYYIL---VRDLLEVTDIVDAVNKII 163 LY+Y+GG FA ELP P+ S E+ ++ + E AV+K + Sbjct: 83 LYAYVGGVFAKELPYPLGNVIGGGRHAEGSTSIQEFLVIPVGAKTFFEAQRANAAVHKQL 142 Query: 164 --------------------SEVGNKVSIEELSKASESVGMELGLEVALGI--------- 194 +++ ++ + E LS+A + V ELG++V +GI Sbjct: 143 KKIFKERGIFAAKGDEGAWAAQISDEQAFEILSEAIQRVEDELGVKVRMGIDVAATELWD 202 Query: 195 ---------KMKRELEIEDVLNIVEDNNVAYIK-PLGPPEL--FLELIAGTHGVFIDGEY 242 K+ E +I + + + ++ YI+ PL + F EL + G+ Sbjct: 203 GERYVYSDRKLTTEEQIAYMAELADRYDLLYIEDPLHEKDFEGFAELTKQVK-CMVCGDD 261 Query: 243 LFRANNILDRR-----YYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADD 297 +F N + ++ N + IKP GTL+ V K + +++ E D+ Sbjct: 262 IFVTNPEIIKKGIEVGAANTVLIKPNQNGTLSGTAKAVKIAKDNGYSVVVSHRSGETEDE 321 Query: 298 TFPHLALGLRCPAM---LISWNSVEKINELNRIAEELGERGRII 338 T HLA+ + ++ + K+NEL RI EEL ++ R++ Sbjct: 322 TLAHLAVAFNAKLIKTGVVGGERISKLNELIRI-EELMDKPRMV 364 >sp|P42848|ENO_THEMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436890|pir||G72323 phosphopyruvate hydratase (EC 4.2.1.11) - Thermotoga maritima (strain MSB8) Length = 429 Score = 101 bits (249), Expect = 1e-20 Identities = 101/348 (29%), Positives = 156/348 (44%), Gaps = 65/348 (18%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 +AV V+E I P LIG +A +Q L+D L E+DGTE+ S +GAN LAVS+A+ARAAAN Sbjct: 67 KAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAAANY 126 Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLEV-TDI 155 + LY Y+GG A LPVP++ +D N E+ I+ R+ L +I Sbjct: 127 LGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAGAEI 186 Query: 156 VDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGIKMK- 197 + KI+ E G N+ +I+ L +A E G + G EV + + Sbjct: 187 FHTLKKILHEAGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIALDCAA 246 Query: 198 ---------------RELEIEDVLNIVEDNNVAY-IKPLGPP------ELFLELIAGT-H 234 E E ++ E+ Y I + P + F+E + Sbjct: 247 SSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFTKRVGN 306 Query: 235 GVFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAE 289 V I G+ L+ R + ++ + N++ IK +GT+T+ + V + +T I++ Sbjct: 307 KVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMTAIISH 366 Query: 290 AKYEPADDTFPHLAL----GLRCPAMLISWNSVEKINELNRIAEELGE 333 E D LA+ G L + K N+L RI EELG+ Sbjct: 367 RSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGK 414 >sp|O85348|ENO_NITEU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|3493583|gb|AAC33442.1| (AF061753) enolase; 2-phospho-D-glycerate hydrolase [Nitrosomonas europaea] Length = 428 Score = 99.5 bits (244), Expect = 5e-20 Identities = 113/416 (27%), Positives = 176/416 (42%), Gaps = 86/416 (20%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP------IEENPMLHIAEARR-- 51 MS I ++I R ++ G ++E DV + G GR + P E L +A+R Sbjct: 1 MSAIVDVIAREIIDSRGNPTIEADVLLESGVLGRASVPSGASVGTREAVELRDGDAQRYY 60 Query: 52 ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 AV V+ I ++G DA+EQ ID L E+DG+E+ S +GAN LAVS+A+A+ Sbjct: 61 GKGVLKAVESVNGEISETIMGLDAMEQCFIDKTLIELDGSENKSRLGANAILAVSLAVAK 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFASD----------ENF--------------- 140 AAA + LY Y+GG A LPVP++ + + F Sbjct: 121 AAAEESGLPLYRYLGGINAKWLPVPMMNLVNGGVHANNRLDMQEFMIIPLGLPNLREAVR 180 Query: 141 ---EYYILVRDLLE----VTDIVDAVNKIISEVGNKVSIEELSKASESVGMELGLEVALG 193 E + +R LL T + D S N+ ++ + +A + G + G EVA+G Sbjct: 181 CGAEVFSTLRTLLNKRNLPTTVGDEGGFAPSFARNEEALALIVQAIDEAGYQPGSEVAIG 240 Query: 194 I---------KMKRELEIEDVLNIVEDNNVAYIK------PLGPPE------------LF 226 + + K L++ D L + V Y+ P+ E L Sbjct: 241 VDCASSEFFREGKYHLDV-DGLGLTSAQFVDYLATWVEKYPIISIEDGMSEQDWEGWGLL 299 Query: 227 LELIAGTHGVFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDVKSE 281 E + T V + G+ +F N + R N++ IK +GTLT+ N + K Sbjct: 300 TERLGKT--VQLVGDDVFVTNTRILKEGISRNIANSILIKINQIGTLTETLNAIEMAKCA 357 Query: 282 KITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333 T I++ E D T +A+ L + + K N+L RI E+LGE Sbjct: 358 GYTAIVSHRSGETEDTTIADIAVATNALQIKTGSLSRSDRLAKYNQLLRIEEDLGE 413 >pir||D75251 enolase - Deinococcus radiodurans (strain R1) >gi|6460466|gb|AAF12173.1|AE002092_11 (AE002092) enolase [Deinococcus radiodurans] Length = 422 Score = 99.1 bits (243), Expect = 7e-20 Identities = 109/415 (26%), Positives = 175/415 (41%), Gaps = 89/415 (21%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASPIEENPMLHIA-------------EA 49 I+ +I R V+ G +VE +V D GF GR P + H A Sbjct: 3 IEKVIAREVLDSRGNPTVEAEVHLDSGFSGRAIVPSGASTGSHEALELRDGGERYMGKGV 62 Query: 50 RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109 RAV V E +GP LIG DA EQ ID L ++DGT + ++G N LAVS+A ARAAA Sbjct: 63 ERAVQNVREALGPALIGMDASEQAAIDKALMDVDGTSNKGNMGGNAILAVSLATARAAAA 122 Query: 110 SKDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV-------RDLLEV-TD 154 D+ LY Y+GG+ A LPVP++ + +F+ ++++ R+ L + Sbjct: 123 ELDIPLYRYLGGSNAKTLPVPMMNVINGGAHADNSVDFQEFMVMPVGAPSFREALRYGAE 182 Query: 155 IVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGI--- 194 + K++S G N+ ++E L +A + G E G ++ + + Sbjct: 183 TFHHLKKVLSGRGYNTNVGDEGGFAPDLKSNEEALEVLLEAIQQAGYEPGKDICIALDPA 242 Query: 195 -------------KMKRELEIEDVLNIVEDNNVAYIKPL-------------GPPELFLE 228 R L +++++ D Y P+ G L + Sbjct: 243 VTELYKDGQYHLESEGRVLSSDEMIDFWADWTSRY--PIVSIEDGLAEDDWDGWERLTAK 300 Query: 229 LIAGTHGVFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKI 283 + A T V G+ LF R +DR+ NA+ +K +G+LT+ + + K Sbjct: 301 VGAKTQLV---GDDLFVTNPERLQQGIDRKVGNAILVKVNQIGSLTESMDAIELAKRHHY 357 Query: 284 TPILAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELGER 334 I++ E D LA+ + S + K N+L RI ++LG+R Sbjct: 358 GTIISHRSGESEDAFIADLAVATNAGQIKTGSASRSDRIAKYNQLLRIEDQLGDR 412 >pir||A81841 phosphopyruvate hydratase (EC 4.2.1.11) NMA1495 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7380143|emb|CAB84728.1| (AL162756) enolase [Neisseria meningitidis Z2491] Length = 428 Score = 98.7 bits (242), Expect = 9e-20 Identities = 110/416 (26%), Positives = 176/416 (41%), Gaps = 86/416 (20%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP----IEENPMLHIAEARR---- 51 MS I +I R ++ G +VE DV + G GR A P + L + + + Sbjct: 1 MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYS 60 Query: 52 ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 AV V+ I LIG DA EQ ID + E+DGTE+ ++GAN LAVS+A+AR Sbjct: 61 GKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVAR 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV-------RDLLE 151 AAA + LY Y+GG LPVP++ + N + ++++ R+ L Sbjct: 121 AAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALR 180 Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193 +I A+ K+ G +K +++ + +A+E+ G + G +V Sbjct: 181 CGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFA 240 Query: 194 IKM---------KRELEIED-----------VLNIVEDNNVAYIKPLGPPE-------LF 226 + K LE E + +V + + I+ G E L Sbjct: 241 LDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIED-GMDENDWEGWKLL 299 Query: 227 LELIAGTHGVFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSE 281 E + G V + G+ LF N +++ NAL +K +GTL++ V+ K Sbjct: 300 TEKLGGK--VQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRN 357 Query: 282 KITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333 + +++ E D T LA+ C L + + K N+L RI EEL E Sbjct: 358 RYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAE 413 >pir||D81100 enolase NMB1285 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226525|gb|AAF41661.1| (AE002477) enolase [Neisseria meningitidis MC58] Length = 428 Score = 98.7 bits (242), Expect = 9e-20 Identities = 110/416 (26%), Positives = 176/416 (41%), Gaps = 86/416 (20%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP----IEENPMLHIAEARR---- 51 MS I +I R ++ G +VE DV + G GR A P + L + + + Sbjct: 1 MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYS 60 Query: 52 ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 AV V+ I LIG DA EQ ID + E+DGTE+ ++GAN LAVS+A+AR Sbjct: 61 GKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVAR 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV-------RDLLE 151 AAA + LY Y+GG LPVP++ + N + ++++ R+ L Sbjct: 121 AAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALR 180 Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193 +I A+ K+ G +K +++ + +A+E+ G + G +V Sbjct: 181 CGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFA 240 Query: 194 IKM---------KRELEIED-----------VLNIVEDNNVAYIKPLGPPE-------LF 226 + K LE E + +V + + I+ G E L Sbjct: 241 LDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIED-GMDENDWEGWKLL 299 Query: 227 LELIAGTHGVFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSE 281 E + G V + G+ LF N +++ NAL +K +GTL++ V+ K Sbjct: 300 TEKLGGR--VQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRN 357 Query: 282 KITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333 + +++ E D T LA+ C L + + K N+L RI EEL E Sbjct: 358 RYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAE 413 >pir||A41835 phosphopyruvate hydratase (EC 4.2.1.11) - Bacillus subtilis >gi|460259|gb|AAA21681.1| (L29475) enolase [Bacillus subtilis] Length = 430 Score = 98.3 bits (241), Expect = 1e-19 Identities = 113/415 (27%), Positives = 177/415 (42%), Gaps = 82/415 (19%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51 M I ++ R V+ G +VEV+V T+ G FGR P + + A R Sbjct: 1 MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGQYEAVELRDGDKDRYL 60 Query: 52 ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 AV+ V+EII PEL+GFD EQ ID L E+DGTE+ +GAN L VS+A AR Sbjct: 61 GKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACAR 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLE 151 AAA+ + LY Y+GG + LPVP++ +D N E+ I+ R+ L Sbjct: 121 AAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALR 180 Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193 + I ++ ++S G N+ +++ + +A E G + G EV L Sbjct: 181 MGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLA 240 Query: 194 IKM-----------KRELEIEDVLNIVEDNNVAYIKPLGP-PELFLE------------L 229 + K L E V+ + Y + + P + +E L Sbjct: 241 MDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKL 300 Query: 230 IAGTHG--VFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDVKSEK 282 + G V + G+ LF N + N++ IK +GTLT+ ++ + K Sbjct: 301 LTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAG 360 Query: 283 ITPILAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELGE 333 T +++ E D T +A+ + S V K N+L RI ++L E Sbjct: 361 YTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAE 415 >sp|P37869|ENO_BACSU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436878|pir||B69620 phosphopyruvate hydratase (EC 4.2.1.11) [validated] - Bacillus subtilis >gi|2635903|emb|CAB15395.1| (Z99121) enolase [Bacillus subtilis] Length = 430 Score = 97.9 bits (240), Expect = 1e-19 Identities = 113/415 (27%), Positives = 177/415 (42%), Gaps = 82/415 (19%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51 M I ++ R V+ G +VEV+V T+ G FGR P + + A R Sbjct: 1 MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYL 60 Query: 52 ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 AV+ V+EII PEL+GFD EQ ID L E+DGTE+ +GAN L VS+A AR Sbjct: 61 GKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACAR 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLE 151 AAA+ + LY Y+GG + LPVP++ +D N E+ I+ R+ L Sbjct: 121 AAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALR 180 Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193 + I ++ ++S G N+ +++ + +A E G + G EV L Sbjct: 181 MGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLA 240 Query: 194 IKM-----------KRELEIEDVLNIVEDNNVAYIKPLGP-PELFLE------------L 229 + K L E V+ + Y + + P + +E L Sbjct: 241 MDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKL 300 Query: 230 IAGTHG--VFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDVKSEK 282 + G V + G+ LF N + N++ IK +GTLT+ ++ + K Sbjct: 301 LTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAG 360 Query: 283 ITPILAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELGE 333 T +++ E D T +A+ + S V K N+L RI ++L E Sbjct: 361 YTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAE 415 >sp|P29201|ENO_HALMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|68311|pir||NOHSM phosphopyruvate hydratase (EC 4.2.1.11) - Haloarcula marismortui >gi|148781|gb|AAA73101.1| (M76567) 2-phosphoglycerate dehydratase [Haloarcula marismortui] Length = 400 Score = 97.1 bits (238), Expect = 3e-19 Identities = 107/397 (26%), Positives = 176/397 (43%), Gaps = 68/397 (17%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIA---EARRAVSEV 56 M++I +I R V+ G +VE DV T+ G FGR +P + + A A A+++ Sbjct: 1 MTLITDIRLRRVLDSRGNATVEADVLTESGGFGRGKAPSGASTGEYEAIELPANEAIAKA 60 Query: 57 DEIIGPELIG-FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSL 115 E P LIG A Q +D+ L DGT+DFS IGAN+A+A+S+A A+A A+ L Sbjct: 61 REEALPRLIGEVHAGNQRDVDTALHAADGTDDFSGIGANSAVAISMAAAKAGADVLGAPL 120 Query: 116 YSYIGGTF-ATELPVPIIQFASDENFEYYILVRDLL-------EVTDIVDA-------VN 160 Y ++GGTF E P P+ E+ +++ L V + V A V+ Sbjct: 121 YQHLGGTFRGNEYPTPLGNIIGGEHAADATNIQEFLAAPVGAPSVEEAVFANAAVHQEVH 180 Query: 161 KIISE----------------VGNKVSIEELSKASESVGMELGLEVALGIKMKR------ 198 I+++ V + + E + +A E+V + G ++ G+ + R Sbjct: 181 DILADRDLPAGKGDEGAWAPSVSDDEAFEIMDEAVETVADDFGFAISFGLDVARAELYDD 240 Query: 199 --------------ELEIEDVLNIVEDNNVAYIK-PLGPP--ELFLELIAGTHG-VFIDG 240 E +IE + VE+ ++ Y++ PL E F +L A + G Sbjct: 241 EADGYVYDDGVKSTEEQIEYIAGKVEEYDLVYVEDPLDENDYEAFADLTAQVGDQTLVCG 300 Query: 241 EYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPA 295 + LF R ++ N++ IKP +GTLTD + + + +++ E Sbjct: 301 DDLFVTNVERLQAGINADAGNSILIKPNQIGTLTDAVDAIELATASGYESVVSHRSGETE 360 Query: 296 DDTFPHLALGLRCPAM---LISWNSVEKINELNRIAE 329 D T HLA+ P + + K+NEL RI + Sbjct: 361 DTTIAHLAVATDAPFIKTGAVGGERTAKLNELIRIED 397 >sp|P96377|ENO_MYCTU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436874|pir||B70623 probable enolase - Mycobacterium tuberculosis (strain H37RV) >gi|1870005|emb|CAB06856.1| (Z92539) eno [Mycobacterium tuberculosis] Length = 429 Score = 92.4 bits (226), Expect = 7e-18 Identities = 107/414 (25%), Positives = 172/414 (40%), Gaps = 78/414 (18%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAE----------- 48 M +I+ + R ++ G +VEV+VA +G F R A P + H A Sbjct: 1 MPIIEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGG 60 Query: 49 --ARRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARA 106 ++AV V + IGP +IG +A +Q L+D L ++DGT D S +G N L VS+A+A+A Sbjct: 61 KGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKA 120 Query: 107 AANSKDMSLYSYIGGTFATELPVPIIQFASD----------ENF---------------- 140 AA+S ++ L+ Y+GG A LPVP++ + + F Sbjct: 121 AADSAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRW 180 Query: 141 --EYYILVRDLLE----VTDIVDAVNKIISEVGNKVSIEELSKASESVGMELGLEVALGI 194 E Y ++ +L+ T + D G +++ +S+A ES G+ G +VAL + Sbjct: 181 GAEVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALAL 240 Query: 195 KMKRELEIEDVLNIVEDNNVA--------YIKPLGP-PELFLE------------LIAGT 233 D V + Y LG P + +E + + Sbjct: 241 DAAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTAS 300 Query: 234 HG--VFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPI 286 G V I G+ +F R ++R NAL +K +GTLT+ + V + Sbjct: 301 IGDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTM 360 Query: 287 LAEAKYEPADDTFPHLALGLRCPAMLIS----WNSVEKINELNRIAEELGERGR 336 ++ E D LA+ + + V K N+L RI E LG+ R Sbjct: 361 ISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAAR 414 >pir||T33721 phosphopyruvate hydratase (EC 4.2.1.11) eno - Zymomonas mobilis >gi|3089611|gb|AAC70360.1| (AF086791) enolase [Zymomonas mobilis] Length = 377 Score = 92.4 bits (226), Expect = 7e-18 Identities = 73/213 (34%), Positives = 112/213 (52%), Gaps = 22/213 (10%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51 M+ I +I GR VV G +VEVDV ++G FGR A P + +H A R Sbjct: 1 MTAIVSIHGRQVVDSRGNPTVEVDVTLEDGSFGRAAVPSGASTGVHEAVELRDGDKTRWG 60 Query: 52 ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 AV V+ I +IG +A +QELID + ++DGT + GAN L VS+A+A+ Sbjct: 61 GKGVTKAVHAVNNEIANAIIGLEAEDQELIDQTMIKLDGTPNKGKFGANAILGVSLAVAK 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENFEYYILVRDLLEVTDIVDAVN 160 AAA ++ + LY Y+GGT A LPVP++ +D ++ + + + I +AV Sbjct: 121 AAAEARGLPLYRYVGGTAAHVLPVPMMNIVNGGMHADNPIDFQEFMIAPVGASSINEAV- 179 Query: 161 KIISEVGNKVSIEELSKA-SESVGMELGLEVAL 192 +I +EV + + E +K + +VG E G +L Sbjct: 180 RIGTEVSHTLKKELSAKGMNTNVGDEGGFAPSL 212 >dbj|BAA81815.1| (AB029313) enolase [Streptococcus intermedius] Length = 434 Score = 91.7 bits (224), Expect = 1e-17 Identities = 101/419 (24%), Positives = 170/419 (40%), Gaps = 86/419 (20%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAE----------- 48 MS+I ++ R V+ G ++EV+V T+ G FGR P + H A Sbjct: 1 MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYG 60 Query: 49 ---ARRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 ++AV V+ II +IG+D +Q+ ID + +DGT + +GAN L VSIA+AR Sbjct: 61 GLGTQKAVDNVNNIIAEAVIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVAR 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFASDEN-------FEYYILV--------RDLL 150 AAA+ ++ LYSY+GG LP P++ + + F+ +++V L Sbjct: 121 AAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIVPAGAPTFKEALR 180 Query: 151 EVTDIVDAVNKIISE-----------------VGNKVSIEELSKASESVGMELGLEVALG 193 +I A+ KI+ G + +E + A E+ G G +V LG Sbjct: 181 WGAEIFHALKKILKSRGLATAVGDEGGFAPRFDGTEDGVETILAAIEAAGYVPGKDVFLG 240 Query: 194 IK------MKRELEIEDVLNI--------VEDNNVAYIKPLGPPELFLELIAGTHGVFID 239 +E ++ D D + Y++ L + + G D Sbjct: 241 FDCASSEFYDKERKVYDYTKFEGEGAAVRTADEQIDYLEELVNKYPIITIEDGMDENDWD 300 Query: 240 ----------------GEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDV 278 G+ F N ++ N++ IK +GTLT+ ++ + Sbjct: 301 GWKKLTERLGKKVQPVGDDFFVTNTSYLEKGINEACANSILIKVNQIGTLTETFDAIEMA 360 Query: 279 KSEKITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333 K T +++ E D T +A+ L + + K N+L RI ++LGE Sbjct: 361 KEAGYTAVVSHRSGETEDSTIADIAVAANAGQIKTGSLSRTDRIAKYNQLLRIEDQLGE 419 >emb|CAC09537.1| (AL442120) enolase [Streptomyces coelicolor] Length = 426 Score = 91.7 bits (224), Expect = 1e-17 Identities = 101/414 (24%), Positives = 172/414 (41%), Gaps = 84/414 (20%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASPI-------------EENPMLHI 46 M I ++ R ++ G +VEV+V D+G GR A P + +P ++ Sbjct: 1 MPSIDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGASTGAFEAIELRDGDPSRYL 60 Query: 47 AEA-RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 + +AV V E IGPEL+G+DA EQ LID ++++D T++ +GAN L VS+A+A Sbjct: 61 GKGVEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDNKGSLGANAILGVSLAVAH 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYI-------LVRDLL 150 AA+ + D+ L+ Y+GG A LPVP++ +D N E+ I L Sbjct: 121 AASEASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVDIQEFMIAPIGAESFSEALR 180 Query: 151 EVTDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193 ++ + K++ G N+ +++ + +A + G G ++AL Sbjct: 181 WGAEVYHTLKKVLKNKGLATGLGDEGGFAPNLGSNREALDLILEAIKEAGYTPGEQIALA 240 Query: 194 IKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFID-------------- 239 + + +D E N + + E + EL+ V I+ Sbjct: 241 LDVAASEFYKDGSYAFEGKNRSAAE---MTEYYAELVEAYPLVSIEDPLFEDDWDGWNTI 297 Query: 240 -----------GEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKI 283 G+ LF N ++ NAL +K +G+LT+ + V + Sbjct: 298 TAKLGDKVQLVGDDLFVTNPERLARGIEENSANALLVKVNQIGSLTETLDAVELAQRNGF 357 Query: 284 TPILAEAKYEPADDTFPHLALGLRCPAMLIS----WNSVEKINELNRIAEELGE 333 +++ E D T LA+ C + V K N+L RI E L + Sbjct: 358 KCMMSHRSGETEDVTIADLAVATNCGQIKTGAPARSERVAKYNQLLRIEEILDD 411 >sp|O66778|ENO_AQUAE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436875|pir||F70343 enolase - Aquifex aeolicus >gi|2983135|gb|AAC06738.1| (AE000692) enolase [Aquifex aeolicus] Length = 426 Score = 91.7 bits (224), Expect = 1e-17 Identities = 107/410 (26%), Positives = 174/410 (42%), Gaps = 78/410 (19%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPI-------------EENPMLHI 46 MS I+ + GR V+ G +VEV+V + G GR P + +P ++ Sbjct: 1 MSRIKRVHGREVLDSRGNPTVEVEVELESGALGRAIVPSGASTGEREALELRDGDPKRYL 60 Query: 47 AEA-RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 + +AV V+ +I L+G + Q ID L E+DGTE+ S +GAN L S+A+AR Sbjct: 61 GKGVLKAVDNVNGVIAKALVGLEPYNQREIDQILIELDGTENKSKLGANAILGTSMAVAR 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLE 151 AAAN + LY Y+GG F LPVP++ +D N E+ I+ R+ L Sbjct: 121 AAANELGIPLYEYLGGKFGYRLPVPLMNVINGGAHADNNLDIQEFMIVPVCGGAFREALR 180 Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193 + + KI+ E G ++ +++ L +A E G + G ++ L Sbjct: 181 AGVETFHHLKKILKEKGYSTNVGDEGGFAPNLNSSEEALDILMQAIEKAGYKPGEDILLA 240 Query: 194 IKMK--------------RELEIEDVLNIVEDNNVAY-IKPLGPP------ELFLELIAG 232 + + +E E+++ E Y I + P E + E+ Sbjct: 241 LDVASSEFYENGVYKFEGKERSAEEMIEFYEKLIQKYPIISIEDPMSENDWEGWKEITKR 300 Query: 233 T-HGVFIDGEYLFRANNILDRR-----YYNALSIKPINLGTLTDLYNFVNDVKSEKITPI 286 V + G+ LF N + R+ NA+ +K +GT+++ + V K + I Sbjct: 301 LGDKVQLVGDDLFTTNPKILRKGIEEGVANAILVKLNQIGTVSETLDTVMLAKERNYSAI 360 Query: 287 LAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELG 332 ++ E D HLA+ + S + K NEL RI E LG Sbjct: 361 ISHRSGETEDTFISHLAVATNAGQIKTGSASRTDRIAKYNELLRIEERLG 410 >sp|Q60173|ENO_METJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|2118303|pir||A64329 phosphopyruvate hydratase (EC 4.2.1.11) - Methanococcus jannaschii >gi|1590967|gb|AAB98220.1| (U67479) enolase (eno) [Methanococcus jannaschii] Length = 427 Score = 90.1 bits (220), Expect = 3e-17 Identities = 86/281 (30%), Positives = 139/281 (48%), Gaps = 38/281 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATD-EGFGRFASPIEENPMLHIAEARR----------- 51 I++I+ R V+ G +VEV+V T G+G P + H A R Sbjct: 11 IKDIVAREVIDSRGNPTVEVEVITKGNGYGSAIVPSGASTGTHEALELRDKEKRFGGKGV 70 Query: 52 --AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109 AV V+ II PE++G+DA Q ID+ + E+DGT + S +GAN LAVS+A+A+AAA Sbjct: 71 LMAVENVNSIIRPEILGYDARMQREIDTIMIELDGTPNKSRLGANAILAVSLAVAKAAAA 130 Query: 110 SKDMSLYSYIGGTFATELPVPIIQF-------ASDENFEYYILVRDLLEVTDIVDAV--N 160 + + LY Y+GG + +PVP++ +D + + ++++ + T I +AV Sbjct: 131 TAKIPLYKYLGGFNSYVMPVPMMNVINGGKHAGNDLDLQEFMIMP--VGATSISEAVRMG 188 Query: 161 KIISEVGNKVSIEELSKASESVGMELGLEVALGIKMKRE---LEIEDVLNIVEDNNVAYI 217 + V V +E+ K + +VG E G A +K RE L E V ++ V + Sbjct: 189 SEVYHVLKNVILEKYGKNAVNVGDEGGF--APPLKTSREALDLLTESVKKAGYEDEVVFA 246 Query: 218 KPLGPPELFLELIAGTHGVFIDGEYLFRANNILDRRYYNAL 258 E + + G + +++G+ L R +LD YY AL Sbjct: 247 LDAAASEFYKD---GYY--YVEGKKLTR-EELLD--YYKAL 279 >sp|O69174|ENO_STAAU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (LAMININ BINDING PROTEIN) >gi|11268974|pir||T47276 phosphopyruvate hydratase (EC 4.2.1.11) [imported] - Staphylococcus aureus >gi|3152725|gb|AAC17130.1| (AF065394) enolase [Staphylococcus aureus] Length = 434 Score = 89.7 bits (219), Expect = 4e-17 Identities = 104/422 (24%), Positives = 171/422 (39%), Gaps = 86/422 (20%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51 M +I ++ R V+ G +VEV+V T+ G FGR P + H A R Sbjct: 1 MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYL 60 Query: 52 ------AVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAI 103 AV V+EII PE+I F ++Q ID + +DGT + +GAN L VSIA+ Sbjct: 61 GKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAV 120 Query: 104 ARAAANSKDMSLYSYIGGTFATELPVPIIQFASDEN-------FEYYILV--------RD 148 ARAAA+ LY Y+GG +LPVP++ + + F+ ++++ Sbjct: 121 ARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKES 180 Query: 149 LLEVTDIVDAVNKIISE-----------------VGNKVSIEELSKASESVGMELGLEVA 191 L T+I + I+S+ G + ++E + +A E+ G + G EV Sbjct: 181 LRWGTEIFHNLKSILSQRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVF 240 Query: 192 LGIKMK------------RELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGT------ 233 LG + E E V Y++ L + + G Sbjct: 241 LGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWD 300 Query: 234 ----------HGVFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDV 278 V + G+ LF N ++ N++ IK +GTLT+ ++ + Sbjct: 301 GWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMA 360 Query: 279 KSEKITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGER 334 + T +++ E D T +A+ L + + K N+L RI +EL E Sbjct: 361 QKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFET 420 Query: 335 GR 336 + Sbjct: 421 AK 422 >sp|P48285|ENO_HELPY ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436877|pir||S58684 phosphopyruvate hydratase (EC 4.2.1.11) - Helicobacter pylori (strains 26695 and others) >gi|2313236|gb|AAD07219.1| (AE000536) enolase (eno) [Helicobacter pylori 26695] Length = 426 Score = 89.7 bits (219), Expect = 4e-17 Identities = 85/342 (24%), Positives = 147/342 (42%), Gaps = 63/342 (18%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 RA V+ +I LIG +A+ Q +D L +DGT +++++GAN L VS+A+ARA+A + Sbjct: 66 RACENVNSVIKHHLIGLEAINQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKA 125 Query: 111 KDMSLYSYIGGTFATELPVPIIQFASD--------------------ENF--------EY 142 ++ LY Y+GG A LPVP++ + E+F E Sbjct: 126 LNLPLYRYLGGANALTLPVPMLNIINGGTHANNSIDFQEYMIMPLGFESFKEALRASAEV 185 Query: 143 YILVRDLL----EVTDIVDAVNKIISEVGNKVSIEELSKASESVGMELGLEVALGIKMKR 198 Y ++ LL ++T + D + N +E +S+A E G +LG E+AL + + Sbjct: 186 YHTLKKLLDGKNQLTSVGDEGGFAPNFSNNVEPLEVISQAIEKAGYKLGEEIALALDVAS 245 Query: 199 ELEIEDVLN--------IVEDNN-VAYIKPLGPPELFLELIAGT---------------- 233 +++ N I++ + VAY K L + + G Sbjct: 246 SELVDENFNYHLKGENKILDSHELVAYYKELVAKYPIVSIEDGLSEDDWEGWAFLSKELG 305 Query: 234 HGVFIDGEYLFRANNIL-----DRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILA 288 + + G+ LF N L ++ NA+ IKP +GT+++ + K +++ Sbjct: 306 RQIQLVGDDLFVTNASLLQKGIEKNIANAVLIKPNQIGTISETLETIRLAKHHAYQCVMS 365 Query: 289 EAKYEPADDTFPHLALGLRCPAMLI-SWNSVEKINELNRIAE 329 E D A+ L + S E+I + NR+ E Sbjct: 366 HRSGESEDSFIADFAVALNTGEIKTGSTARSERIAKYNRLLE 407 >sp|Q9ZMS6|ENO_HELPJ ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436886|pir||H71967 enolase - Helicobacter pylori (strain J99) >gi|4154655|gb|AAD05723.1| (AE001453) ENOLASE [Helicobacter pylori J99] Length = 426 Score = 88.9 bits (217), Expect = 7e-17 Identities = 81/342 (23%), Positives = 146/342 (42%), Gaps = 63/342 (18%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 RA V+ +I LIG +A Q +D L +DGT +++++GAN L VS+A+ARA+A + Sbjct: 66 RACENVNSVIKHHLIGLEATNQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKA 125 Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV--------RDLLEVTDI 155 ++ LY Y+GG A LPVP++ + +F+ Y+++ L ++ Sbjct: 126 LNLPLYRYLGGANALTLPVPMLNIINGGTHANNSIDFQEYMIMPLGFESFKEALRASAEV 185 Query: 156 VDAVNKIISEVGNKVSI-----------------EELSKASESVGMELGLEVALGIKMKR 198 + K++ E S+ E +S+A E G +LG E+AL + + Sbjct: 186 YHTLKKLLDEKNQLTSVGDEGGFAPNFNNNVEPLEIISQAIEKAGYKLGEEIALALDVAS 245 Query: 199 ELEIEDVLN--------IVEDNN-VAYIKPLGPPELFLELIAGT---------------- 233 +++ N I++ + VAY K L + + G Sbjct: 246 SELVDEHFNYHLKGENKILDSHELVAYYKELVAKYPIVSIEDGLSEDDWEGWAFLSKELG 305 Query: 234 HGVFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILA 288 + + G+ LF N +++ NA+ IKP +GT+++ + K +++ Sbjct: 306 RQIQLVGDDLFVTNASILQKGIEKNVANAILIKPNQIGTISETLETIRLAKHHAYQCVIS 365 Query: 289 EAKYEPADDTFPHLALGLRCPAMLI-SWNSVEKINELNRIAE 329 E D A+ L + S E+I + NR+ E Sbjct: 366 HRSGESEDSFIADFAVALNTGEIKTGSTARSERIAKYNRLLE 407 >sp|O30885|ENO_CAMFE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|2642185|gb|AAB86924.1| (AF020677) enolase [Campylobacter fetus] Length = 207 Score = 86.2 bits (210), Expect = 5e-16 Identities = 45/137 (32%), Positives = 79/137 (56%), Gaps = 15/137 (10%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 +A+ V+ +I E+ G DA Q+ ID + +DGT+++S IGAN L VS+A+ARAAANS Sbjct: 65 KAIKNVNSMIAEEICGKDAYNQKAIDDAMLALDGTDNYSRIGANAVLGVSMAVARAAANS 124 Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV--------RDLLEVTDI 155 ++ LY Y+GG A LPVP+ + +F+ ++++ L T++ Sbjct: 125 LNIPLYRYLGGANACTLPVPMFNIINGGAHANNSVDFQEFMIMPFGFSKFSNALRAATEV 184 Query: 156 VDAVNKIISEVGNKVSI 172 + KI++++G+ ++ Sbjct: 185 YQTLKKILNDLGHSTAV 201 >emb|CAC12011.1| (AL445065) enolase related protein [Thermoplasma acidophilum] Length = 401 Score = 85.0 bits (207), Expect = 1e-15 Identities = 97/395 (24%), Positives = 176/395 (44%), Gaps = 71/395 (17%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIE----ENPMLHIAEAR--RAVSEVD 57 I+ I R V+ G ++VE DV GFGR ++P E ++ +++ ++ + Sbjct: 5 IEEIKVRKVLDSRGNFTVEADVTVPNGFGRTSAPAGASTGETEVIAFSKSGIDASIQFFE 64 Query: 58 EIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYS 117 + LIGF+A++Q D L +IDG+ +FS++G N A A+S+++A+AAA S + LY Sbjct: 65 SKVKRSLIGFNALDQSGFDKLLTDIDGSGNFSNLGGNLATALSMSVAKAAAQSLGIPLYR 124 Query: 118 YIGGTFATELPVPI-------------------IQFASDENF--EYYILVRDLLEVTDIV 156 Y+GG +T +P P+ + A F YI V + D++ Sbjct: 125 YVGGIRST-IPRPMGNVIGGGKHARNGTSIQEFLVSAQGSTFLESAYINVLVHRRIGDML 183 Query: 157 DAVNKIIS-----------EVGNKVSIEELSKASESVGMELGLEVALGIKM--------- 196 K IS + ++ + E L++A + + E +++ G+ Sbjct: 184 SDKFKDISIGVGDERTWSVNLSDEEAFEILNEAVKEISSEKKVKIYTGVDFAADSLYENG 243 Query: 197 ---------KRELEIEDVLNIVEDNNVAYIK-PLGPPEL--FLELIA--GTHGVFIDGEY 242 R+ +I+ ++I +D V YI+ P+ + F E+ A G + + G+ Sbjct: 244 KYVYKHTTKSRDEQIDYAISISKDFGVYYIEDPMYDTDFDGFAEITARIGDRSLIV-GDD 302 Query: 243 LFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADD 297 L+ N ++++ NA+ IK +GTL+ V + I++ E DD Sbjct: 303 LYTTNPDRIRKGVEKKSTNAVLIKVNQIGTLSAAREAVAVATFAGMKNIVSHRSGETTDD 362 Query: 298 TFPHLALGLRCPAM---LISWNSVEKINELNRIAE 329 HL++ + +I V K+NE+ RI E Sbjct: 363 FLAHLSVAFGSTFVKTGVIGGERVAKLNEIARIEE 397 >dbj|BAB07786.1| (AB046715) enolase [Desulfovibrio vulgaris] Length = 434 Score = 84.7 bits (206), Expect = 1e-15 Identities = 100/415 (24%), Positives = 171/415 (41%), Gaps = 80/415 (19%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASP----IEENPMLHIAEA------ 49 MS I ++ R ++ G +VEV+V+ + G GR A P L + + Sbjct: 1 MSTIVSVWAREILDSRGNPTVEVEVSLESGHTGRAAVPSGASTGSREALEMRDGDKGRYK 60 Query: 50 ----RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 +AV V I ++G D++ Q +D+ L ++DGT++ S +GAN L VS+A AR Sbjct: 61 GKGVEKAVDNVMGEIAEAIVGLDSLRQVQVDNTLLDLDGTDNKSRLGANAMLGVSLATAR 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFASD--------ENFEYYIL------VRDLLE 151 AA++ + LY Y+GG A LPVP++ + + E+ I+ RD L Sbjct: 121 AASSFLGLPLYQYLGGVNAKVLPVPLMNIINGGAHAPNNLDIQEFMIMPIGAATFRDALR 180 Query: 152 V-TDIVDAVNKIISEVGNKVSIEE-----------------LSKASESVGMELGLEVALG 193 + + + +++ G+ S+ + + KA E G G E+AL Sbjct: 181 MGAETFHTLKALLAADGHVTSVGDEGGFAPNLKNHDEAFRYIMKAIEEAGYIPGAEIALA 240 Query: 194 IKMKRELEIEDVLNIVED-----NNVAYIKPLGPPELFLELIAGTHG------------- 235 I +D ++ +N ++ LG LI+ G Sbjct: 241 IDAAASEFHKDGKYVLAGEGKNLSNSEMVEWLGEFTTRYPLISIEDGLAEADWDGWRELT 300 Query: 236 ------VFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKIT 284 + + G+ +F N +D N++ IK +GTLT+ + + K T Sbjct: 301 YKLGDTIQLVGDDIFVTNPDILAEGIDEGVANSILIKLNQIGTLTETLDTIEMAKQAAYT 360 Query: 285 PILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGERG 335 +++ E D LA+GL L + + K N+L RI E+L + G Sbjct: 361 TVISHRSGETEDHFISDLAVGLNAGQIKTGSLCRSDRLAKYNQLLRIEEDLDDTG 415 >gb|AAF13454.1|AF205070_1 (AF205070) enolase [Mastigamoeba balamuthi] Length = 439 Score = 84.3 bits (205), Expect = 2e-15 Identities = 102/424 (24%), Positives = 179/424 (42%), Gaps = 92/424 (21%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR--------- 50 MS I+++ R ++ G +VEVD+ T++G R A P + ++ A E R Sbjct: 1 MSTIKSVFAREILDSRGNPTVEVDLTTEKGLFRSAVPSGASTGIYEACELRDGDKSRYLG 60 Query: 51 ----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARA 106 +AV V++I+ P+LIG D +Q ID + +IDGTE+ +H+GAN L S+++ RA Sbjct: 61 KGVLKAVENVNKILAPKLIGLDVTKQGEIDRLMLQIDGTENKTHLGANAILGCSMSVCRA 120 Query: 107 AANSKDMSLYSYI---GGTFATELPVP--------------------------------I 131 AA + + LY YI G + LP+P Sbjct: 121 AAAFRGLPLYRYIAELSGNKSPMLPLPCFNVINGGEHAGNKLAMQEFMICPTGATSFHEA 180 Query: 132 IQFASD--ENFEYYILVRDLLEVTDIVD----AVNKIISEVGNKVSIEELSKASESVGME 185 ++ A++ N + I R ++ T++ D A N + G ++ +E + +A + +E Sbjct: 181 LRMAAETYHNLKLVIKKRYGMDATNVGDEGGFAPNIQANHEGLELIVEAIKQAGYTGKIE 240 Query: 186 LGLEVA-------------LGIKMKRELEIEDVL-------NIVEDNNVAY-IKPLGPP- 223 +G++VA LG K+ + + D+L + E+ Y I + P Sbjct: 241 IGMDVAASSFWDAKESKYDLGFKVPADKKTPDMLVSGEGLIKLYEEWTSKYPIWSIEDPF 300 Query: 224 --------ELFLELIAGTHGVFIDGEYLFRANNILD---RRYYNALSIKPINLGTLTDLY 272 F ELI + D + I++ ++ NAL +K +G++++ Sbjct: 301 DQDDWATYTRFTELIRNRIQIVGDDLLVTNPKRIVEARNKKACNALLLKLNQIGSVSEAV 360 Query: 273 NFVNDVKSEKITPILAEAKYEPADDTFPHLALGLRCPAMLIS----WNSVEKINELNRIA 328 + +++ E D L +GL C + + K N+L RI Sbjct: 361 EACRLAREVNWGVMVSHRSGETEDAFIADLVVGLGCGQIKTGAPCRSERLAKYNQLLRIE 420 Query: 329 EELG 332 EELG Sbjct: 421 EELG 424 >sp|Q57651|Y198_METJA HYPOTHETICAL PROTEIN MJ0198 >gi|2128174|pir||G64324 hypothetical protein MJ0198 - Methanococcus jannaschii >gi|1592276|gb|AAB98193.1| (U67476) M. jannaschii predicted coding region MJ0198 [Methanococcus jannaschii] Length = 314 Score = 83.9 bits (204), Expect = 2e-15 Identities = 74/327 (22%), Positives = 145/327 (43%), Gaps = 63/327 (19%) Query: 2 SVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEIIG 61 +VI I V +G V + T+ G ++ + A+++V+ +I Sbjct: 3 NVIIEKISAKEVFKGAKIKVMITTMTNISIGY--------DIIEVNNPEEAIADVENVIA 54 Query: 62 PELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIGG 121 PELIG+ A + + IDS + E S A+ +SI++ARAA+NS D+ L+ ++GG Sbjct: 55 PELIGYPATDIDFIDSLICET------SVNNPTVAMGISISVARAASNSLDIPLFKFLGG 108 Query: 122 TFATELPVPI--IQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKA- 178 TELP+ I D+N I++ D +E DIV+ K+ + + SI + A Sbjct: 109 ALTTELPIVASGILVDKDKNELIPIVMADSIE--DIVNLYLKLTDVLSHDYSIVNIDGAY 166 Query: 179 ---------------SESVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPP 223 + + + L++ LG+ K+E V+D +++ I L Sbjct: 167 TCKDIFNEIPKIRNLIDEIKEDEDLDILLGLSSKKE--------TVKDKDLSQIDYLEVE 218 Query: 224 E-LFLELIAGTHGVFIDGEYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEK 282 E + + T ++ + ++ + + P +GT+T++Y ++N + + Sbjct: 219 EPVEFDGFLCTDSIYEESDF---------------VKVFPYEMGTITEMYYYINYIMDKG 263 Query: 283 ITPILAEAKYEPADDTFPHLALGLRCP 309 + P++ + +F H+A+ + P Sbjct: 264 LYPVIF-----GNNSSFAHIAVSFKVP 285 >gb|AAC47644.1| (U85832) enolase [Stylochus zebra] Length = 168 Score = 83.1 bits (202), Expect = 4e-15 Identities = 56/145 (38%), Positives = 78/145 (53%), Gaps = 18/145 (12%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51 I+ I GR + G +VEVD+ T++G R A P + +H A R Sbjct: 3 IKKIHGRQIFDSRGNPTVEVDITTEKGMFRAAVPSGASTGVHEALEMRDKAKEYMGKGVL 62 Query: 52 -AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAA 108 AV+ V+ +IGP LI GF VEQE ID+++ E+DGTE+ + +GAN L VS+A+ +A A Sbjct: 63 NAVNNVNNVIGPALIAKGFSVVEQENIDNFMLELDGTENKAKLGANAILGVSLAVLKAGA 122 Query: 109 NSKDMSLYSYI---GGTFATELPVP 130 K LY +I G LPVP Sbjct: 123 AQKGTPLYRHIADLAGNNEVILPVP 147 >gb|AAF73201.1|AF152348_1 (AF152348) enolase [Trypanosoma brucei brucei] Length = 429 Score = 81.9 bits (199), Expect = 1e-14 Identities = 55/144 (38%), Positives = 79/144 (54%), Gaps = 17/144 (11%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASP------IEENPMLHIAEARR------ 51 IQ + GR V+ G +VEV+V T+ G R A P + E L + +R Sbjct: 3 IQKVHGREVLDSRGNPTVEVEVTTERGVFRSAVPSGASTGVYEACELRDGDKKRYVGKGC 62 Query: 52 --AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109 AV V+E+IGP LIG D ++QE +D+ + +DGT + +GAN L S+AI++AAA Sbjct: 63 LQAVKNVNEVIGPALIGRDELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISKAAAA 122 Query: 110 SKDMSLYSY---IGGTFATELPVP 130 +K + LY Y + GT LPVP Sbjct: 123 AKGVPLYRYLASLAGTKELRLPVP 146 >sp|Q9Z7A6|ENO_CHLPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436889|pir||A72034 enolase - Chlamydophila pneumoniae (strain CWL029) >gi|4377111|gb|AAD18938.1| (AE001661) Enolase [Chlamydophila pneumoniae CWL029] Length = 428 Score = 81.5 bits (198), Expect = 1e-14 Identities = 92/345 (26%), Positives = 138/345 (39%), Gaps = 65/345 (18%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 +AV V EI+ P + G EQ LIDS + + DG+ + +GAN L VS+A A AAA + Sbjct: 68 QAVKNVKEILFPLVKGCSVYEQSLIDSLMMDSDGSPNKETLGANAILGVSLATAHAAAAT 127 Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-----SDENFEYYILVRDLLEVTDIVDAVN----- 160 LY Y+GG FA LP P++ +D E+ + + + I +AVN Sbjct: 128 LRRPLYRYLGGCFACSLPCPMMNLINGGMHADNGLEFQEFMIRPIGASSIKEAVNMGADV 187 Query: 161 -----KIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGIKMKR 198 K++ E G N+ ++E L A E G G +++L + Sbjct: 188 FHTLKKLLHERGLSTGVGDEGGFAPNLASNEEALELLLLAIEKAGFTPGKDISLALDCAA 247 Query: 199 ----------------ELEIEDVLNIVEDNNVAYIKPLGPPE------LFLELIAGTHGV 236 E +I + N+ + + I+ E L E++ V Sbjct: 248 SSFYNVKTGTYDGRHYEEQIAILSNLCDRYPIDSIEDGLAEEDYDGWALLTEVLG--EKV 305 Query: 237 FIDGEYLFRANNIL-----DRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAK 291 I G+ LF N L N++ IKP +GTLT+ + + T I++ Sbjct: 306 QIVGDDLFVTNPELILEGISNGLANSVLIKPNQIGTLTETVYAIKLAQMAGYTTIISHRS 365 Query: 292 YEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELG 332 E D T LA+ L V K N L I EELG Sbjct: 366 GETTDTTIADLAVAFNAGQIKTGSLSRSERVAKYNRLMEIEEELG 410 >sp|P42448|ENO_CAMJE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|11268976|pir||E81264 phosphopyruvate hydratase (EC 4.2.1.11) Cj1672c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6969088|emb|CAB73659.1| (AL139079) enolase [Campylobacter jejuni] Length = 414 Score = 81.1 bits (197), Expect = 2e-14 Identities = 40/81 (49%), Positives = 56/81 (68%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 +AV+ V+E I E++G DA Q +D L E+DGT ++S++GAN L VS+A ARAAA + Sbjct: 65 KAVANVNETIADEILGLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATARAAAAA 124 Query: 111 KDMSLYSYIGGTFATELPVPI 131 M LY Y+GG A+ LPVP+ Sbjct: 125 LGMPLYRYLGGANASILPVPM 145 >sp|P08324|ENO_ECOLI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7428364|pir||NOEC phosphopyruvate hydratase (EC 4.2.1.11) - Escherichia coli (strain K-12) >gi|882673|gb|AAA69289.1| (U29580) enolase [Escherichia coli] >gi|1789141|gb|AAC75821.1| (AE000361) enolase [Escherichia coli K12] Length = 432 Score = 80.0 bits (194), Expect = 4e-14 Identities = 107/427 (25%), Positives = 182/427 (42%), Gaps = 101/427 (23%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASP----IEENPMLHIAEA------ 49 MS I IIGR ++ G +VE +V + GF G A+P L + + Sbjct: 1 MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFL 60 Query: 50 ----RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 +AV+ V+ I LIG DA +Q ID + ++DGTE+ S GAN LAVS+A A+ Sbjct: 61 GKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAK 120 Query: 106 AAANSKDMSLYSYIGGTFAT----ELPVPIIQFA-----SDENF---EYYI------LVR 147 AAA +K M LY +I T +PVP++ +D N E+ I V+ Sbjct: 121 AAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVK 180 Query: 148 DLLEV-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLE 189 + + + +++ + K++ G N ++ +++A ++ G ELG + Sbjct: 181 EAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKD 240 Query: 190 VALGI------------------------------------KMKRELEIEDVLNIVEDNN 213 + L + K + IED L+ + + Sbjct: 241 ITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDG 300 Query: 214 VAY-IKPLGPPELFLELIAGTHGVFIDGEYLFRANNILDRRYYNALSIKPINLGTLTDLY 272 AY K LG ++L+ +F+ + + +++ N++ IK +G+LT+ Sbjct: 301 FAYQTKVLGDK---IQLVG--DDLFVTNTKILKEG--IEKGIANSILIKFNQIGSLTETL 353 Query: 273 NFVNDVKSEKITPILAEAKYEPADDTFPHLALG-----LRCPAMLISWNSVEKINELNRI 327 + K T +++ E D T LA+G ++ +M S + V K N+L RI Sbjct: 354 AAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRS-DRVAKYNQLIRI 412 Query: 328 AEELGER 334 E LGE+ Sbjct: 413 EEALGEK 419 >pir||E82076 enolase VC2447 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657023|gb|AAF95589.1| (AE004314) enolase [Vibrio cholerae] Length = 433 Score = 80.0 bits (194), Expect = 4e-14 Identities = 103/421 (24%), Positives = 176/421 (41%), Gaps = 88/421 (20%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASPIEENPMLHIA-EAR-------- 50 MS I ++GR ++ G +VE +V + GF G A+P + A E R Sbjct: 1 MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFL 60 Query: 51 -----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 +A++ V+ I L+G DA +Q ID + ++DGTE+ S+ GAN LAVS+A A+ Sbjct: 61 GKGVLKALAAVNGPIADALVGKDAKDQATIDQIMIDLDGTENKSNFGANAILAVSLANAK 120 Query: 106 AAANSKDMSLYSYIGGTFAT----ELPVPIIQFA-----SDENFEYYILVRDLLEVTDIV 156 AAA +K M LY +I T +P+P++ +D N + + + + Sbjct: 121 AAAAAKGMPLYEHIAELNGTPGVFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLK 180 Query: 157 DAVN----------KIISEVG-----------------NKVSIEELSKASESVGMELGLE 189 +AV K++ G N ++E +++A + G +LG + Sbjct: 181 EAVRMGAEVFHNLAKVLKSKGYNTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYKLGTD 240 Query: 190 VALGIKM---------KRELEIEDVLNIVEDNNVA-YIKPLGPPELFLELIAGT------ 233 + L + K+E ++ I N + +++ L + + G Sbjct: 241 ITLAMDCAASEFYDAEKKEYNLKGEGRIFTSNGFSDFLEELTEKFPIVSIEDGLDESDWE 300 Query: 234 ----------HGVFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDV 278 + I G+ LF N +D N++ IK +G+LT+ + Sbjct: 301 GFAYQTEKLGKKIQIVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMA 360 Query: 279 KSEKITPILAEAKYEPADDTFPHLALG-----LRCPAMLISWNSVEKINELNRIAEELGE 333 K T +++ E D T LA+G ++ +M S + V K N+L RI E LG Sbjct: 361 KDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRS-DRVAKYNQLIRIEEALGS 419 Query: 334 R 334 R Sbjct: 420 R 420 >emb|CAA57795.1| (X82400) enolase [Escherichia coli] Length = 437 Score = 80.0 bits (194), Expect = 4e-14 Identities = 108/429 (25%), Positives = 181/429 (42%), Gaps = 101/429 (23%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASP----IEENPMLHIAEA------ 49 MS I IIGR ++ G +VE +V + GF G A+P L + + Sbjct: 1 MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFL 60 Query: 50 ----RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 +AV+ V+ I LIG DA +Q ID + ++DGTE S GAN LAVS+A A+ Sbjct: 61 GKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEKKSKFGANAILAVSLANAK 120 Query: 106 AAANSKDMSLYSYIGGTFAT----ELPVPIIQFA-----SDENF---EYYI------LVR 147 AAA +K M LY +I T +PVP++ +D N E+ I V+ Sbjct: 121 AAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVK 180 Query: 148 DLLEV-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLE 189 + + + +++ + K++ G N ++ +++A ++ G ELG + Sbjct: 181 EAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNDEALAVIAEAVKAAGYELGKD 240 Query: 190 VALGI------------------------------------KMKRELEIEDVLNIVEDNN 213 + L + K + IED L+ + + Sbjct: 241 ITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDG 300 Query: 214 VAY-IKPLGPPELFLELIAGTHGVFIDGEYLFRANNILDRRYYNALSIKPINLGTLTDLY 272 AY K LG ++L+ +F+ + + +++ N+ IK +G+LT+ Sbjct: 301 FAYQTKVLGDK---IQLVG--DDLFVTNTKILKEG--IEKGIANSYLIKFNQIGSLTETL 353 Query: 273 NFVNDVKSEKITPILAEAKYEPADDTFPHLALG-----LRCPAMLISWNSVEKINELNRI 327 + K T +++ E D T LA+G ++ +M S + V K N+L RI Sbjct: 354 AAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRS-DRVAKYNQLIRI 412 Query: 328 AEELGERGR 336 E LGE+ R Sbjct: 413 EEALGEKAR 421 >emb|CAB94910.1| (AJ401152) enolase [Enterococcus faecalis] Length = 432 Score = 79.6 bits (193), Expect = 5e-14 Identities = 54/147 (36%), Positives = 81/147 (54%), Gaps = 15/147 (10%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIA-------EAR-- 50 MS+I +I R V+ G ++EV+V T+ G FGR P + + A +AR Sbjct: 1 MSIITDIYAREVLDSRGNPTIEVEVYTESGAFGRGMVPSGASTGEYEAVELRDGDKARYL 60 Query: 51 -----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 +AV V+ II +IG+D +Q ID + ++DGT + +GAN L VSIA+AR Sbjct: 61 GKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIDLDGTPNKGKLGANAILGVSIAVAR 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPII 132 AAA+ ++ LY Y+GG LP P++ Sbjct: 121 AAADYLEVPLYHYLGGFNTKVLPTPMM 147 >gb|AAC47645.1| (U85834) enolase [Tubularia sp.] Length = 166 Score = 77.6 bits (188), Expect = 2e-13 Identities = 53/149 (35%), Positives = 80/149 (53%), Gaps = 19/149 (12%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPI-------------EENPMLHIA 47 MS + I R ++ G +VEVD+AT G R A P +++P ++ Sbjct: 1 MSGVTKIHAREILDSRGNPTVEVDLATSRGVFRAAVPSGASTGIYEALELRDKDPKRYLG 60 Query: 48 E-ARRAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIA 104 + A +AVS +++IIGP LI D +Q +D + E+DGTE+ S +GAN LAVS+A+ Sbjct: 61 KGALKAVSNINDIIGPALISKNIDCTQQGEVDKIMLELDGTENKSKLGANAILAVSLAVC 120 Query: 105 RAAANSKDMSLYSYI---GGTFATELPVP 130 +A A K + LY +I G +PVP Sbjct: 121 KAGAAHKGVPLYKHIADLAGNSKVIMPVP 149 >sp|O84591|ENO_CHLTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436872|pir||D71496 probable enolase - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3329030|gb|AAC68189.1| (AE001329) Enolase [Chlamydia trachomatis] Length = 424 Score = 76.9 bits (186), Expect = 3e-13 Identities = 98/406 (24%), Positives = 167/406 (40%), Gaps = 76/406 (18%) Query: 3 VIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP------IEENPMLHIAEARR---- 51 VI +I R ++ G ++ V V T+ G FG P I+E L + +R Sbjct: 5 VISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQGK 64 Query: 52 ----AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 A+S V++++ P L GF +Q D+ + + DGT + +GAN L VS+A+A+AA Sbjct: 65 GVLQAISNVEKVLMPALQGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALAKAA 124 Query: 108 ANSKDMSLYSYIGGTFATELPVPIIQF-------ASDENFEYYIL----VRDLLEV---- 152 AN+ LY Y+GG+F+ LP P++ + F+ +++ L E Sbjct: 125 ANTLQRPLYRYLGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLTEAVRMG 184 Query: 153 TDIVDAVNKIISE-----------------VGNKVSIEELSKASESVGMELGLEVALGIK 195 ++ +A+ KI+ N +++ L A E+ G +++L + Sbjct: 185 AEVFNALKKILQNRQLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPREDISLALD 244 Query: 196 MKREL----------------EIEDVLNIVEDNNVAYIKPLGPPELF--LELIAGTHG-- 235 ++ + + E + I+ E F +L++ T G Sbjct: 245 CAASSFYNTQDKTYDGKSYADQVGILAELCEHYPIDSIEDGLAEEDFEGWKLLSETLGDR 304 Query: 236 VFIDGEYLFRANNIL-----DRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEA 290 V + G+ LF N+ L + NA+ IKP +GTLT+ + + IL+ Sbjct: 305 VQLVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATIQGYATILSHR 364 Query: 291 KYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELG 332 E D T LA+ L + K N L I EE+G Sbjct: 365 SGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEEEMG 410 >pir||A72477 probable enolase APE2458 - Aeropyrum pernix (strain K1) >gi|5106162|dbj|BAA81473.1| (AP000064) 432aa long hypothetical enolase [Aeropyrum pernix] Length = 432 Score = 76.5 bits (185), Expect = 4e-13 Identities = 83/345 (24%), Positives = 146/345 (42%), Gaps = 70/345 (20%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 RAVS ++ ++ P L G DA Q ID L E+DGT + S +G NT A+SIA++RAAA Sbjct: 69 RAVSLLNTVVAPRLEGVDARRQAQIDRLLIELDGTPNKSRLGGNTTTALSIAVSRAAAAQ 128 Query: 111 KDMSLYSYIGGTFATELPVPI-------IQFASDENFEYYILV----------------- 146 + L+ Y+GG A LP+P+ + ++ +F+ ++++ Sbjct: 129 ARLELFQYLGGAGARRLPIPLLNVINGGVHAGNELDFQEFMIIPYGFESFTEAMRAAVET 188 Query: 147 ----RDLLEVTDIVDAVNKIISEVGN--------KVSIEELSKASESVGMELGLEVALGI 194 + LL+ AVN + + G + +++ L A E G + G E+ALGI Sbjct: 189 YGELKSLLKDRYGASAVN--VGDEGGFAPPMRSAEEALKTLVDAVEKAGYQPGSEIALGI 246 Query: 195 KMK--------------RELEIEDVLN----IVEDNNVAYIK-PLGPP--ELFLELI--A 231 + L E++L+ +VE + Y++ P E F + Sbjct: 247 DAAASQLYSNGRYSVEGKSLSREELLSLYQRLVEQYPIVYLEDPFSEDDYEGFKAAVDAL 306 Query: 232 GTHGVFIDGEYLF----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPIL 287 T + + + L R + L +K +GTLT+ + + I I+ Sbjct: 307 STETIIVGDDLLVTNPQRVKEASALKAVTGLLVKVNQVGTLTEALEAIQAARDRGIVHIV 366 Query: 288 AEAKYEPADDTFPHLALGLRCPAMLISWNSV---EKINELNRIAE 329 + + D LA+ A++I + E+ ++ NR+ E Sbjct: 367 SHRSGDTEDTFIADLAVATE--ALMIKTGAPARGERTSKYNRLLE 409 >sp|Q27527|ENO_CAEEL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7508094|pir||T25040 hypothetical protein T21B10.2 - Caenorhabditis elegans >gi|3879986|emb|CAA92692.1| (Z68318) contains similarity to Pfam domain: PF00113 (Enol-ase), Score=1030.7, E-value=0, N=1~cDNA EST EMBL:Z14384 comes from this gene~cDNA EST EMBL:T02304 comes from this gene~cDNA EST yk99b2.5 comes from this gene~cDNA EST yk55g12.5 comes from this > Length = 434 Score = 75.7 bits (183), Expect = 7e-13 Identities = 55/146 (37%), Positives = 77/146 (52%), Gaps = 19/146 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 I I R + G +VEVD+ T++G R A P + +H A E R Sbjct: 3 ITKIHARQIYDSRGNPTVEVDLFTEKGVFRAAVPSGASTGVHEALELRDGDKAVHLGKGV 62 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AVS ++E I P LI GFD Q+ ID ++ +DG+E+ ++GAN L VS+A+A+A Sbjct: 63 LKAVSNINEKIAPALIAKGFDVTAQKDIDDFMMALDGSENKGNLGANAILGVSLAVAKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130 A K + LY YI GT LPVP Sbjct: 123 AVHKGLPLYKYIAELAGTGKVVLPVP 148 >sp|P40370|ENO1_SCHPO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|1076907|pir||JC4036 phosphopyruvate hydratase (EC 4.2.1.11) - fission yeast (Schizosaccharomyces pombe) >gi|535442|gb|AAA70080.1| (U13799) enolase [Schizosaccharomyces pombe] Length = 439 Score = 75.3 bits (182), Expect = 9e-13 Identities = 51/147 (34%), Positives = 72/147 (48%), Gaps = 20/147 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51 IQ + R + GG +VEVD+ T+ G R P + + A R Sbjct: 3 IQKVFARQIYALGGNPTVEVDLTTETGIHRAIVPSGASTGIWEALEMRDGDKTKWGGKGV 62 Query: 52 --AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 AV V+ II P ++ D +Q+ D +L ++DGTE+ S +GAN L VS+AI RA Sbjct: 63 LKAVGNVNNIIAPAVVKANLDVTDQKAADEFLLKLDGTENKSKLGANAILGVSMAICRAG 122 Query: 108 ANSKDMSLYSYIGGTFATE----LPVP 130 A K + L+ YI F T+ LPVP Sbjct: 123 AAQKKLPLWKYIAENFGTKGPYVLPVP 149 >gb|AAC43380.1| (U13756) enolase [Helicobacter pylori] Length = 178 Score = 75.3 bits (182), Expect = 9e-13 Identities = 35/82 (42%), Positives = 54/82 (65%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 RA V+ +I LIG +A Q +D L +DGT +++++GAN L VS+A+ARA+A + Sbjct: 66 RACENVNSVIKHHLIGLEATNQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKA 125 Query: 111 KDMSLYSYIGGTFATELPVPII 132 ++ LY Y+GG A LPVP++ Sbjct: 126 LNLPLYRYLGGANALTLPVPML 147 >emb|CAB96125.1| (AJ272111) enolase [Euglena gracilis] Length = 431 Score = 75.3 bits (182), Expect = 9e-13 Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 18/149 (12%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASP----IEENPMLHIAEARRAV-- 53 M VI+ + R ++ G +VEVDV D G GR A P E + + + +AV Sbjct: 1 MPVIKTVKARQILDSRGNPTVEVDVILDNGLLGRGAVPSGASTGEYEAVELRDGDKAVYL 60 Query: 54 --------SEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 V+ I+ P+L+G D EQ ID+ + E+DGT + IGAN L VS+A+ R Sbjct: 61 GKGVLKSVEAVNTIVAPKLVGLDPTEQLKIDNLMRELDGTPNKGKIGANGILGVSMAVCR 120 Query: 106 AAANSKDMSLYSYIG---GTFATELPVPI 131 AAA K + LY +IG G ++PVP+ Sbjct: 121 AAALVKGVPLYRHIGDLHGNKTFQMPVPM 149 >gb|AAC47639.1| (U85833) enolase [Hymenolepis diminuta] Length = 168 Score = 74.9 bits (181), Expect = 1e-12 Identities = 55/149 (36%), Positives = 77/149 (50%), Gaps = 20/149 (13%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR--------- 51 MS+++ I R + G +VEVD+ TD G R A P + +H A R Sbjct: 1 MSIVK-IHARQIFDSRGNPTVEVDLFTDNGMFRAAVPSGASTGVHEAVELRDNDKANYMG 59 Query: 52 -----AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIA 104 AV V++II PELI GF EQE ID ++ ++DGT++ +GAN L VS+A+ Sbjct: 60 KGVLNAVKNVNDIIAPELIKKGFKVTEQEAIDEFMIKLDGTKNKGKLGANAILGVSLAVC 119 Query: 105 RAAANSKDMSLYSYI---GGTFATELPVP 130 +A A K + LY +I G LPVP Sbjct: 120 KAGAALKGVPLYRHIAELAGNKDVILPVP 148 >sp|P15007|ENO_DROME ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|84950|pir||S07586 phosphopyruvate hydratase (EC 4.2.1.11) - fruit fly (Drosophila melanogaster) >gi|7946|emb|CAA34895.1| (X17034) enolase (AA 1-433) [Drosophila melanogaster] Length = 433 Score = 74.1 bits (179), Expect = 2e-12 Identities = 74/266 (27%), Positives = 121/266 (44%), Gaps = 38/266 (14%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA--------------EA 49 I+ I R + G +VEVD+ T+ G R A P + +H A Sbjct: 3 IKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSV 62 Query: 50 RRAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV V++ +GPELI D V+Q ID+++ ++DGTE+ S GAN L VS+A+A+A Sbjct: 63 LKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVPIIQFASDENF--------EYYILVRDLLEVTDIV 156 A K + LY +I G LPVP + + E+ IL T+ + Sbjct: 123 AAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182 Query: 157 DAVNKIISEVGNKVSIEELSKASESVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAY 216 +++ + N + + + +VG E G A I+ +E LN++ D +A Sbjct: 183 KMGSEVYHHLKNVIK-AKFGLDATAVGDEGGF--APNIQSNKE-----ALNLISD-AIAK 233 Query: 217 IKPLGPPELFLELIAGTHGVFIDGEY 242 G E+ +++ A + DG+Y Sbjct: 234 AGYTGKIEIGMDVAASE--FYKDGQY 257 >gb|AAF51344.1| (AE003585) Eno gene product [Drosophila melanogaster] Length = 433 Score = 74.1 bits (179), Expect = 2e-12 Identities = 74/266 (27%), Positives = 121/266 (44%), Gaps = 38/266 (14%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA--------------EA 49 I+ I R + G +VEVD+ T+ G R A P + +H A Sbjct: 3 IKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSV 62 Query: 50 RRAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV V++ +GPELI D V+Q ID+++ ++DGTE+ S GAN L VS+A+A+A Sbjct: 63 LKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVPIIQFASDENF--------EYYILVRDLLEVTDIV 156 A K + LY +I G LPVP + + E+ IL T+ + Sbjct: 123 AAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182 Query: 157 DAVNKIISEVGNKVSIEELSKASESVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAY 216 +++ + N + + + +VG E G A I+ +E LN++ D +A Sbjct: 183 KMGSEVYHHLKNVIK-AKFGLDATAVGDEGGF--APNIQSNKE-----ALNLISD-AIAK 233 Query: 217 IKPLGPPELFLELIAGTHGVFIDGEY 242 G E+ +++ A + DG+Y Sbjct: 234 AGYTGKIEIGMDVAASE--FYKDGQY 257 >sp|P74934|ENO_TREPA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436871|pir||F71278 probable enolase (eno) - syphilis spirochete >gi|1575361|gb|AAB39979.1| (U61534) 2-phospho-D-glycerate hydrolase [Treponema pallidum] >gi|3323125|gb|AAC65781.1| (AE001252) enolase (eno) [Treponema pallidum] Length = 432 Score = 73.4 bits (177), Expect = 4e-12 Identities = 54/146 (36%), Positives = 75/146 (50%), Gaps = 15/146 (10%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP-------IEENPMLHIAEAR-- 50 MS I I R ++ G +VEVDV+ +G FGR P E M + R Sbjct: 1 MSDIACIEAREIIDSRGNPTVEVDVSLSDGSFGRACVPSGASTGEFEALEMRDGDKERYN 60 Query: 51 -----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 +AV V+ +I L G DA+ Q ID + +DGT++ S +GAN L VS+A AR Sbjct: 61 GKGVLKAVGTVNTLIADTLEGMDALNQGEIDHAMRNLDGTDNKSKLGANAMLGVSMACAR 120 Query: 106 AAANSKDMSLYSYIGGTFATELPVPI 131 AAA+ + LY Y+GG +PVP+ Sbjct: 121 AAADFLGVPLYRYLGGVHTFRMPVPM 146 >sp|P07323|ENOG_RAT GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE) (NSE) >gi|92215|pir||A24742 phosphopyruvate hydratase (EC 4.2.1.11) gamma - rat >gi|204042|gb|AAA41119.1| (M11931) neuron-specific enolase [Rattus norvegicus] >gi|1619609|emb|CAA30556.1| (X07727) enol_cds [Rattus norvegicus] >gi|2465396|gb|AAB72088.1| (AF019973) neuron-specific enolase [Rattus norvegicus] >gi|225406|prf||1302225A enolase gamma,neuron specific [Rattus norvegicus] Length = 434 Score = 73.0 bits (176), Expect = 5e-12 Identities = 54/146 (36%), Positives = 75/146 (50%), Gaps = 19/146 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 IQ I R ++ G +VEVD+ T +G R A P + ++ A E R Sbjct: 3 IQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV ++ I P LI G VEQE +D+ + E+DGTE+ S GAN L VS+A+ +A Sbjct: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130 A KD+ LY +I G LPVP Sbjct: 123 AAEKDLPLYRHIAQLAGNSDLILPVP 148 >emb|CAC16971.1| (AL450350) enolase [Streptomyces coelicolor] Length = 434 Score = 73.0 bits (176), Expect = 5e-12 Identities = 50/150 (33%), Positives = 76/150 (50%), Gaps = 15/150 (10%) Query: 2 SVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPI--------------EENPMLHI 46 + I+ + R ++ G +VEVDV ++G GR A P E+ H Sbjct: 10 AAIETVTARRIIDSRGNPTVEVDVVLEDGSLGRAAVPSGASTGAREAVELRDEDPTRWHG 69 Query: 47 AEARRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARA 106 RAV+ V+ I + G DA +Q +D+ L +DGT S +GAN L VS+A A+A Sbjct: 70 KGVDRAVAHVNGEIAASVRGRDAADQAGLDAALIALDGTAAKSRLGANALLGVSLAAAKA 129 Query: 107 AANSKDMSLYSYIGGTFATELPVPIIQFAS 136 AA ++ LY Y+GG A LP+P++ + Sbjct: 130 AAAARRQPLYRYLGGADAHLLPLPMMNIVN 159 >sp|P43806|ENO_HAEIN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|1074058|pir||E64103 phosphopyruvate hydratase (EC 4.2.1.11) - Haemophilus influenzae (strain Rd KW20) >gi|1573953|gb|AAC22590.1| (U32775) enolase (eno) [Haemophilus influenzae Rd] Length = 436 Score = 73.0 bits (176), Expect = 5e-12 Identities = 109/429 (25%), Positives = 179/429 (41%), Gaps = 92/429 (21%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASPIEENPMLHIA-EAR-------- 50 M+ I +IGR ++ G +VE +V GF G A+P + A E R Sbjct: 1 MAKIVKVIGREIIDSRGNPTVEAEVHLXGGFVGLAAAPSGASTGSREALELRDGDKSRFL 60 Query: 51 -----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105 +AV+ V+ I ++G DA Q ID + ++DGTE+ S+ GAN LAVS+A A+ Sbjct: 61 GKGVLKAVAAVNNEIAQAIVGKDATNQAEIDQIMIDLDGTENKSNFGANAILAVSLANAK 120 Query: 106 AAANSKDMSLYSYI----GGTFATELPVPIIQFA-----SDENF---EYYI------LVR 147 AAA SK + LY+YI G +P+P++ +D N E+ I +R Sbjct: 121 AAAASKGLPLYAYIAELNGTAGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLR 180 Query: 148 DLLEV-TDIVDAVNKIISEVGNKVSIEE-----------------LSKASESVGMELGLE 189 + L + ++ + K++ G ++ + + +A E G LG + Sbjct: 181 EALRIGAEVFHNLAKVLKAKGMSTAVGDEGGFAPNLASNADALACIKEAVEKAGYVLGKD 240 Query: 190 VALGI---------------KMKRE---LEIEDVLNIVEDNNVAYIKPL-----GPPELF 226 V L + +MK E ++ + +E+ Y P+ G E Sbjct: 241 VTLAMDCASSEFYNKENGMYEMKGEGKSFTSQEFTHYLEELCKEY--PIVSIEDGQDESD 298 Query: 227 LELIAGTHGVFID-----GEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVN 276 E A V D G+ LF N +++ N++ IK +G+LT+ + Sbjct: 299 WEGFAYQTKVLGDRVQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIK 358 Query: 277 DVKSEKITPILAEAKYEPADDTFPHLALG-----LRCPAMLISWNSVEKINELNRIAEEL 331 K T +++ E D T LA+G ++ +M S + + K N+L RI E L Sbjct: 359 MAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRS-DRIAKYNQLIRIEEAL 417 Query: 332 GERGRIITF 340 G F Sbjct: 418 ERAGTPAAF 426 >sp|P08734|ENO_XENLA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|68307|pir||NOXL phosphopyruvate hydratase (EC 4.2.1.11) ENO1 - African clawed frog >gi|64680|emb|CAA68706.1| (Y00718) enolase (AA 1-434) [Xenopus laevis] Length = 434 Score = 73.0 bits (176), Expect = 5e-12 Identities = 105/426 (24%), Positives = 169/426 (39%), Gaps = 99/426 (23%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 I+NI R + G +VEVD+ T +G R A P + ++ A E R Sbjct: 3 IKNIRAREIFDSRGNPTVEVDLYTCKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGV 62 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 RAV V+E +GP L + VEQE ID + E+DGTE+ S GAN L VS+A+ +A Sbjct: 63 GRAVKYVNEFLGPALCTQNLNVVEQEKIDKLMIEMDGTENKSKFGANALLGVSLAVCKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVP---------------------IIQFASDE----- 138 A K + LY +I G LPVP I+ +D Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGADSFKEAM 182 Query: 139 --NFEYYILVRDLL------EVTDIVDAVNKIISEVGNKVSIEELSKASESVG----MEL 186 E Y +++++ + T++ D + + NK ++E L A G + + Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAINKAGYPDKIVI 242 Query: 187 GLEVALG---IKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELI------------- 230 G++VA K +L+ + D+ YI P EL++ + Sbjct: 243 GMDVAASEFYRDGKYDLDFKS-----PDDPSRYISPDKLAELYMSFVKNYPVVSIEDPFD 297 Query: 231 ----------AGTHGVFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFV 275 G+ + G+ L N ++ + N L +K +GT+T+ Sbjct: 298 QDHWEAWTKFTAASGIQVVGDDLTVTNPKRIAKAVEEKACNCLLLKVNQIGTVTESLEAC 357 Query: 276 NDVKSEKITPILAEAKYEPADDTFPHLALGLRCPAMLISW-----NSVEKINELNRIAEE 330 +S +++ E D L +GL C + + + K N+L RI EE Sbjct: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGL-CTGQIKTGAPCRSERLAKYNQLLRIEEE 416 Query: 331 LGERGR 336 LG + R Sbjct: 417 LGSKAR 422 >sp|O52191|ENO_STRTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|2921237|gb|AAC64907.1| (AF027167) enolase [Streptococcus thermophilus] Length = 422 Score = 73.0 bits (176), Expect = 5e-12 Identities = 102/414 (24%), Positives = 162/414 (38%), Gaps = 89/414 (21%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVA-TDEGFGRFASPI------EENPMLHIAEAR------ 50 I+NI R + G +VEVDV TD GR A P E L AR Sbjct: 5 IENIHAREIFDSRGNPTVEVDVRLTDGTLGRAAVPSGASTGDREAVELRDGGARLQGKGV 64 Query: 51 -RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109 +AV+ V+ I L G Q +D + E+DGTE+ S +GAN L VS+AI RAAAN Sbjct: 65 SKAVANVNGEIYEALKGQSPFNQAKLDHLMIELDGTENKSCLGANAILGVSMAIFRAAAN 124 Query: 110 SKDMSLYSYIGGTFATELPVPIIQFASD----------ENFEYYILVRD-----LLEVTD 154 S+ + LY Y GG ELP P + + F + RD L ++ + Sbjct: 125 SEKIPLYRYFGGV-DLELPQPFFNVINGGVHADSGIDVQEFLITPVKRDSFRDGLKKIAN 183 Query: 155 IVDAVNKIISEVGNKVSIEE-----------------LSKASESVGMELGLEVALGIKM- 196 I + KI+S+ G K + + L + +S G G ++A+ I Sbjct: 184 IYHTLKKILSDKGLKTPVGDEGGFAPKLGTTENAIAILYQPIDSAGYFPGEKIAIAIDSS 243 Query: 197 -------KRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHG-------------- 235 K++ + N+ + Y L E + LI+ G Sbjct: 244 SIEFYDDKKKFYRFEGKNLTSKELLTYYDNL--VEKYPALISIEDGFSEHDWEGFAAQTK 301 Query: 236 ------------VFIDGEYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKI 283 +F+ +F+ + + NA+ IK +GT+T+ ++ + Sbjct: 302 ARGQKIQLVGDDIFVTNPTIFKEG--IKKNVANAILIKLNQIGTVTETIETISLARKAGY 359 Query: 284 TPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333 +++ E D ++ + + VEK N+L RI E+LG+ Sbjct: 360 KTMISHRSGETVDSYIADFSVAMHAGQIKSGSMARSERVEKYNQLLRIEEDLGK 413 >emb|CAB94039.1| (AL358652) enolase [Leishmania major] Length = 429 Score = 72.2 bits (174), Expect = 8e-12 Identities = 51/144 (35%), Positives = 77/144 (53%), Gaps = 17/144 (11%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-------EAR------ 50 I+ + R V+ G +VEV++ T+ G R A P + +H A +AR Sbjct: 3 IRKVYAREVLDSRGNPTVEVELMTEAGVFRSAVPSGASTGVHEACELRDGDKARYCGAGC 62 Query: 51 -RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109 +AV V+EI+ P L+G + +Q +D + E+DGT++ S +GAN L S+AI++AAA Sbjct: 63 TQAVKNVNEILAPALVGKEESDQAGLDKMMCELDGTKNKSKLGANAILGCSMAISKAAAA 122 Query: 110 SKDMSLYSYI---GGTFATELPVP 130 + LY YI GT LPVP Sbjct: 123 KAGVPLYRYIASLAGTKDIRLPVP 146 >pir||S43113 phosphopyruvate hydratase (EC 4.2.1.11) - fungus (Cladosporium herbarum) >gi|467660|emb|CAA55070.1| (X78226) phosphopyruvate hydratase [Cladosporium herbarum] Length = 440 Score = 71.8 bits (173), Expect = 1e-11 Identities = 54/149 (36%), Positives = 77/149 (51%), Gaps = 20/149 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 I I R V G +VEVD+ T+ G R P + H A E R Sbjct: 3 ISKIHSRYVYDSRGNPTVEVDIVTETGLHRAIVPSVASTGSHEACELRDGDKSKWAGKGV 62 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV+ V+EII P LI D +Q +D++L ++DGT + + IGAN L VS+A+A+AA Sbjct: 63 TKAVANVNEIIAPALIKENLDVKDQAAVDAFLNKLDGTTNKTKIGANAILGVSMAVAKAA 122 Query: 108 ANSKDMSLYSYIGGTFATE----LPVPII 132 A K + LY++I T+ LPVP + Sbjct: 123 AAEKRVPLYAHISDLSGTKKPFVLPVPFM 151 >sp|P07322|ENOB_CHICK BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (PHOSPHOPYRUVATE HYDRATASE) >gi|1085244|pir||JC4187 phosphopyruvate hydratase (EC 4.2.1.11) beta chain - chicken >gi|1616990|dbj|BAA07133.1| (D37901) enolase [Gallus gallus] Length = 434 Score = 71.8 bits (173), Expect = 1e-11 Identities = 55/148 (37%), Positives = 76/148 (51%), Gaps = 17/148 (11%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 IQ I R ++ G +VEVD+ T +G R A P + +H A E R Sbjct: 3 IQKIHAREILDSRGEPTVEVDLHTAKGHFRAAVPSGASTGIHEALEPRDGDKKRFLGKGV 62 Query: 51 -RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV +++ IGP LI VEQE ID + E+DGTE+ S GAN L VS+A+ +A Sbjct: 63 LKAVEHINKTIGPALIEKKISVVEQEKIDKVMIEMDGTENKSKFGANAILGVSLAVCKAG 122 Query: 108 ANSKDMSLYSYIGGTFA-TELPVPIIQF 134 A K + LY +I TEL +P+ F Sbjct: 123 AAEKGVPLYRHIADLAGNTELILPVPAF 150 >sp|P42040|ENO_CLAHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (ALLERGEN CLA H 6) (CLA H VI) Length = 440 Score = 71.8 bits (173), Expect = 1e-11 Identities = 54/149 (36%), Positives = 77/149 (51%), Gaps = 20/149 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 I I R V G +VEVD+ T+ G R P + H A E R Sbjct: 3 ISKIHSRYVYDSRGNPTVEVDIVTETGLHRAIVPSGASTGSHEACELRDGDKSKWAGKGV 62 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV+ V+EII P LI D +Q +D++L ++DGT + + IGAN L VS+A+A+AA Sbjct: 63 TKAVANVNEIIAPALIKENLDVKDQAAVDAFLNKLDGTTNKTKIGANAILGVSMAVAKAA 122 Query: 108 ANSKDMSLYSYIGGTFATE----LPVPII 132 A K + LY++I T+ LPVP + Sbjct: 123 AAEKRVPLYAHISDLSGTKKPFVLPVPFM 151 >pir||T39737 enolase - fission yeast (Schizosaccharomyces pombe) >gi|4886570|emb|CAB43486.1| (AL050301) enolase [Schizosaccharomyces pombe] >gi|6579195|gb|AAA51399.2| (L37084) phosphopyruvate hydratase [Schizosaccharomyces pombe] Length = 439 Score = 71.4 bits (172), Expect = 1e-11 Identities = 50/147 (34%), Positives = 71/147 (48%), Gaps = 20/147 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51 IQ + R + G +VEVD+ T+ G R P + + A R Sbjct: 3 IQKVFARQIYDSRGNPTVEVDLTTETGIHRAIVPSGASTGIWEALEMRDGDKTKWGGKGV 62 Query: 52 --AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 AV V+ II P ++ D +Q+ D +L ++DGTE+ S +GAN L VS+AI RA Sbjct: 63 LKAVGNVNNIIAPAVVKANLDVTDQKAADEFLLKLDGTENKSKLGANAILGVSMAICRAG 122 Query: 108 ANSKDMSLYSYIGGTFATE----LPVP 130 A K + L+ YI F T+ LPVP Sbjct: 123 AAQKKLPLWKYIAENFGTKGPYVLPVP 149 >pir||JC1039 phosphopyruvate hydratase (EC 4.2.1.11) - rat Length = 434 Score = 71.0 bits (171), Expect = 2e-11 Identities = 53/146 (36%), Positives = 75/146 (51%), Gaps = 19/146 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 IQ I R ++ G +VEVD+ T +G R A P + ++ A E R Sbjct: 3 IQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV ++ I P LI G VEQE +D+ + E+DGTE+ S GAN L VS+A+ +A Sbjct: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130 A K++ LY +I G LPVP Sbjct: 123 AAEKNLPLYRHIAQLAGNSDLILPVP 148 >gb|AAB87890.1| (AF025805) enolase [Drosophila pseudoobscura] Length = 413 Score = 71.0 bits (171), Expect = 2e-11 Identities = 44/128 (34%), Positives = 69/128 (53%), Gaps = 19/128 (14%) Query: 22 EVDVATDEGFGRFASPIEENPMLHIA--------------EARRAVSEVDEIIGPELI-- 65 EVD+ T+ G R A P + +H A +AV+ V++ +GPE+I Sbjct: 1 EVDLTTENGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVAHVNDTLGPEVIKA 60 Query: 66 GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYI---GGT 122 D V+Q +D+++ ++DGTE+ S GAN L +S+A+A+A A K++ LY +I G Sbjct: 61 NLDVVDQAAVDNFMIKLDGTENKSKFGANAILGISLAVAKAGAAKKNVPLYKHIADLAGN 120 Query: 123 FATELPVP 130 LPVP Sbjct: 121 KEIILPVP 128 >gb|AAB87891.1| (AF025806) enolase [Drosophila subobscura] Length = 413 Score = 71.0 bits (171), Expect = 2e-11 Identities = 44/128 (34%), Positives = 69/128 (53%), Gaps = 19/128 (14%) Query: 22 EVDVATDEGFGRFASPIEENPMLHIA--------------EARRAVSEVDEIIGPELI-- 65 EVD+ T+ G R A P + +H A +AV+ V++ +GPE+I Sbjct: 1 EVDLTTEHGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVAHVNDTLGPEVIKA 60 Query: 66 GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYI---GGT 122 D V+Q +D+++ ++DGTE+ S GAN L +S+A+A+A A K++ LY +I G Sbjct: 61 NLDVVDQAAVDNFMIKLDGTENKSKFGANAILGISLAVAKAGAAKKNVPLYKHIADLAGN 120 Query: 123 FATELPVP 130 LPVP Sbjct: 121 KEIILPVP 128 >pir||A23850 phosphopyruvate hydratase (EC 4.2.1.11), skeletal muscle - chicken Length = 433 Score = 70.6 bits (170), Expect = 2e-11 Identities = 55/148 (37%), Positives = 76/148 (51%), Gaps = 17/148 (11%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 IQ I R ++ G +VEVD+ T +G R A P + +H A E R Sbjct: 2 IQKIHAREILDSRGDPTVEVDLHTAKGHFRAAVPSGASTGIHEALELRDGDKKRFLGKGV 61 Query: 51 -RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV +++ IGP LI VEQE ID + E+DGTE+ S GAN L VS+A++ A Sbjct: 62 LKAVEHINKTIGPALIEKKISVVEQEKIDKVVIEMDGTENKSKFGANAILGVSLAVSHAG 121 Query: 108 ANSKDMSLYSYIGGTFA-TELPVPIIQF 134 A K + LY +I TEL +P+ F Sbjct: 122 AAEKGVPLYRHIADLAGNTELILPVPAF 149 >gb|AAD45339.1|AF159529_1 (AF159529) enolase [Trypanosoma brucei] Length = 370 Score = 70.6 bits (170), Expect = 2e-11 Identities = 37/83 (44%), Positives = 54/83 (64%), Gaps = 3/83 (3%) Query: 51 RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110 +AV V+E+IGP LIG D ++QE +D+ + +DGT + +GAN L S+AI++AAA + Sbjct: 41 QAVKNVNEVIGPALIGRDELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISKAAAAA 100 Query: 111 KDMSLYSY---IGGTFATELPVP 130 K + LY Y + GT LPVP Sbjct: 101 KGVPLYRYLASLAGTKELRLPVP 123 >gb|AAF36733.1| (AC016662) putative enolase; 31277-33713 [Arabidopsis thaliana] Length = 477 Score = 70.6 bits (170), Expect = 2e-11 Identities = 46/146 (31%), Positives = 78/146 (52%), Gaps = 16/146 (10%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51 ++ + R ++ G +VEVD+ TD+ + R A P + ++ A R Sbjct: 51 VKGVKARQIIDSRGNPTVEVDLITDDLY-RSAVPSGASTGIYEALELRDGDKSVYGGKGV 109 Query: 52 --AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109 A+ ++E++ P+LIG D Q +D+ + E+DGT + S +GAN L VS+++ RA A Sbjct: 110 LQAIKNINELVAPKLIGVDVRNQADVDALMLELDGTPNKSKLGANAILGVSLSVCRAGAG 169 Query: 110 SKDMSLYSYIGGTFAT-ELPVPIIQF 134 +K + LY +I T T EL +P+ F Sbjct: 170 AKGVPLYKHIQETSGTKELVMPVPAF 195 >emb|CAA31512.1| (X13120) neurone-specific enolase [Homo sapiens] >gi|930101|emb|CAA32505.1| (X14327) gamma enolase [Homo sapiens] Length = 433 Score = 70.2 bits (169), Expect = 3e-11 Identities = 52/146 (35%), Positives = 75/146 (50%), Gaps = 19/146 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 IQ I R ++ G +VEVD+ T +G R A P + ++ A E R Sbjct: 2 IQKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 61 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV ++ I P LI G VEQE +D+ + E+DGTE+ S GAN L VS+A+ +A Sbjct: 62 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 121 Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130 A +++ LY +I G LPVP Sbjct: 122 AAERELPLYRHIAQLAGNSDLILPVP 147 >pir||E81654 enolase TC0876 [imported] - Chlamydia muridarum (strain Nigg) >gi|7190904|gb|AAF39672.1| (AE002354) enolase [Chlamydia muridarum] Length = 424 Score = 70.2 bits (169), Expect = 3e-11 Identities = 48/145 (33%), Positives = 77/145 (53%), Gaps = 15/145 (10%) Query: 3 VIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP------IEENPMLHIAEARR---- 51 VI +I R ++ G ++ V V T+ G FG P I+E L + +R Sbjct: 5 VISDIEAREILDSRGYPTLYVKVITNTGIFGEACVPSGASTGIKEALELRDQDPKRYQGK 64 Query: 52 ----AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 AV+ V++++ P L GF +Q D+ + + DGT + +GAN L VS+A+A+AA Sbjct: 65 GVLQAVANVEKVLLPALQGFSVFDQITADAIMIDADGTSNKEKLGANAILGVSLALAKAA 124 Query: 108 ANSKDMSLYSYIGGTFATELPVPII 132 A + + LY Y+GG F+ LP P++ Sbjct: 125 AATLERPLYRYLGGAFSHVLPCPMM 149 >sp|P09104|ENOG_HUMAN GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE) (NSE) Length = 434 Score = 70.2 bits (169), Expect = 3e-11 Identities = 52/146 (35%), Positives = 75/146 (50%), Gaps = 19/146 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 IQ I R ++ G +VEVD+ T +G R A P + ++ A E R Sbjct: 3 IQKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV ++ I P LI G VEQE +D+ + E+DGTE+ S GAN L VS+A+ +A Sbjct: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130 A +++ LY +I G LPVP Sbjct: 123 AAERELPLYRHIAQLAGNSDLILPVP 148 >gi|7305027 enolase 2, gamma neuronal [Mus musculus] >gi|119348|sp|P17183|ENOG_MOUSE GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE) (NSE) >gi|109805|pir||S10247 phosphopyruvate hydratase (EC 4.2.1.11) gamma - mouse >gi|55495|emb|CAA36606.1| (X52380) gamma-enolase (AA 1-434) [Mus sp.] >gi|2289903|gb|AAC36002.1| (AC002397) ENO2 [Mus musculus] Length = 434 Score = 69.9 bits (168), Expect = 4e-11 Identities = 52/146 (35%), Positives = 75/146 (50%), Gaps = 19/146 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 I+ I R ++ G +VEVD+ T +G R A P + ++ A E R Sbjct: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV ++ I P LI G VEQE +D+ + E+DGTE+ S GAN L VS+A+ +A Sbjct: 63 LKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130 A +D+ LY +I G LPVP Sbjct: 123 AAERDLPLYRHIAQLAGNSDLILPVP 148 >gb|AAC47640.1| (U85826) enolase [Haematoloechus sp.] Length = 168 Score = 69.9 bits (168), Expect = 4e-11 Identities = 52/145 (35%), Positives = 76/145 (51%), Gaps = 18/145 (12%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 I+ I R + G +VEVDV TD+G R A P + +H A E R Sbjct: 3 IKKIHARQIFDSRGNPTVEVDVFTDKGTFRAAVPSGASTGVHEALELRDGGKTYMGKAVL 62 Query: 51 RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAA 108 +A+S V++ I PELI +Q ID+++ ++DGT++ + +GAN L VS+A+ +A A Sbjct: 63 KAISNVNDKIAPELIKANIPVTDQTAIDNFMIKLDGTKNKATLGANAILGVSLAVCKAGA 122 Query: 109 NSKDMSLYSYI---GGTFATELPVP 130 K + LY YI G LPVP Sbjct: 123 AEKGVPLYRYIASLAGNNDVILPVP 147 >gb|AAC47641.1| (U85828) enolase [Lacistorhynchus tenuis] Length = 169 Score = 69.9 bits (168), Expect = 4e-11 Identities = 50/146 (34%), Positives = 73/146 (49%), Gaps = 19/146 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51 I+ I R + G +VEVD+ T +G R A P + +H A R Sbjct: 3 IKTIHARQIFDSRGNPTVEVDLTTAKGMFRAAVPSGASTGVHEAVELRDGVKNQYMGKGV 62 Query: 52 --AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 AV V++I+GPELI G EQ +D ++ ++DGT++ +GAN L VS+A+ +A Sbjct: 63 LKAVDNVNKILGPELIKSGIAVTEQVKVDEFMKKLDGTDNKGKLGANAILGVSLAVCKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130 A K + LY +I G LPVP Sbjct: 123 AAEKGIPLYRHIANLAGNKEIVLPVP 148 >gb|AAC46289.1| (AF000366) enolase homolog [Borrelia burgdorferi] Length = 433 Score = 69.9 bits (168), Expect = 4e-11 Identities = 49/143 (34%), Positives = 69/143 (47%), Gaps = 15/143 (10%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR----------- 51 I I R ++ G +VE DV ++G +GR A P + ++ A R Sbjct: 5 IYEIKARQIIDSRGNPTVEADVILEDGTYGRAAVPSGASTGINEAVELRDGDKSVYMGKG 64 Query: 52 ---AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAA 108 A+ + II PEL G A+ Q ID + E+DGT +GAN LAVS+A A+AAA Sbjct: 65 VLKAIENIKNIIAPELEGMSALNQVAIDRKMLELDGTPTKEKLGANAILAVSMATAKAAA 124 Query: 109 NSKDMSLYSYIGGTFATELPVPI 131 + Y Y+G A LP P+ Sbjct: 125 KYLGLRPYQYLGAYKANILPTPM 147 >sp|O51312|ENO_BORBU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436876|pir||H70141 enolase (eno) homolog - Lyme disease spirochete >gi|2688240|gb|AAC66719.1| (AE001140) enolase (eno) [Borrelia burgdorferi] Length = 433 Score = 69.9 bits (168), Expect = 4e-11 Identities = 49/143 (34%), Positives = 69/143 (47%), Gaps = 15/143 (10%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR----------- 51 I I R ++ G +VE DV ++G +GR A P + ++ A R Sbjct: 5 IYEIKARQIIDSRGNPTVEADVILEDGTYGRAAVPSGASTGINEAVELRDGDKSVYMGKG 64 Query: 52 ---AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAA 108 A+ + II PEL G A+ Q ID + E+DGT +GAN LAVS+A A+AAA Sbjct: 65 VLKAIENIKNIIAPELEGMSALNQVAIDRKMLELDGTPTKEKLGANAILAVSMATAKAAA 124 Query: 109 NSKDMSLYSYIGGTFATELPVPI 131 + Y Y+G A LP P+ Sbjct: 125 KYLGLRPYQYLGAYKANILPTPM 147 >sp|P42894|ENO_NEOFR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|515827|emb|CAA56645.1| (X80474) enolase [Neocallimastix frontalis] Length = 436 Score = 69.5 bits (167), Expect = 5e-11 Identities = 50/147 (34%), Positives = 74/147 (50%), Gaps = 20/147 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 I + R + G +VEV+V TD+G R A P + +H A E R Sbjct: 3 ITKVHARQIFDSRGNPTVEVEVTTDKGLFRAAVPSGASTGVHEALELRDGIKADYVGKGV 62 Query: 51 -RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV V++ I P L+ D Q+ +D +L ++DGT + S +GAN L VS+A+ARA Sbjct: 63 LKAVENVNKTIAPALVAANLDVKNQKAVDDFLLKLDGTPNKSKLGANAILGVSLAVARAG 122 Query: 108 ANSKDMSLYSYIGGTFATE----LPVP 130 A K + LY ++G + LPVP Sbjct: 123 AADKGVPLYQHLGELAGNKGPWILPVP 149 >gi|5803011 enolase 2, (gamma, neuronal); Enolase-2, gamma, neuronal [Homo sapiens] >gi|11436317|ref|XP_006974.1| enolase 2, (gamma, neuronal) [Homo sapiens] >gi|68305|pir||NOHUG phosphopyruvate hydratase (EC 4.2.1.11) gamma - human >gi|31165|emb|CAA36215.1| (X51956) human gamma enolase [Homo sapiens] >gi|182116|gb|AAB59554.1| (M22349) enolase [Homo sapiens] >gi|1732416|gb|AAB51320.1| (U47924) neuron specific gamma-enolase [Homo sapiens] Length = 434 Score = 69.1 bits (166), Expect = 7e-11 Identities = 51/146 (34%), Positives = 75/146 (50%), Gaps = 19/146 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50 I+ I R ++ G +VEVD+ T +G R A P + ++ A E R Sbjct: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 51 -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 +AV ++ I P LI G VEQE +D+ + E+DGTE+ S GAN L VS+A+ +A Sbjct: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130 A +++ LY +I G LPVP Sbjct: 123 AAERELPLYRHIAQLAGNSDLILPVP 148 >sp|P30575|ENO1_CANAL ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|422073|pir||A40624 phosphopyruvate hydratase (EC 4.2.1.11) - yeast (Candida albicans) >gi|170861|gb|AAB46358.1| (L04943) enolase [Candida albicans] >gi|170863|gb|AAA71939.1| (L10290) enolase [Candida albicans] >gi|170865|gb|AAA34341.1| (M93712) enolase [Candida albicans] Length = 440 Score = 68.7 bits (165), Expect = 9e-11 Identities = 57/153 (37%), Positives = 75/153 (48%), Gaps = 25/153 (16%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR--------- 50 MS I R V G +VEVD TD+G R P + +H A E R Sbjct: 1 MSYATKIHARYVYDSRGNPTVEVDFTTDKGLFRSIVPSGASTGVHEALELRDGDKSKWLG 60 Query: 51 ----RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIA 104 +AV+ V++II P LI D V+Q ID +L +DGT + S +GAN L VS+A A Sbjct: 61 KGVLKAVANVNDIIAPALIKAKIDVVDQAKIDEFLLSLDGTPNKSKLGANAILGVSLAAA 120 Query: 105 RAAANSKDMSLYSYIG-------GTFATELPVP 130 AAA ++ + LY +I G F LPVP Sbjct: 121 NAAAAAQGIPLYKHIANISNAKKGKFV--LPVP 151 >gi|6323985 Ymr323wp [Saccharomyces cerevisiae] >gi|1706698|sp|P42222|ERR1_YEAST ENOLASE RELATED PROTEIN 1 >gi|2118301|pir||S69881 phosphopyruvate hydratase (EC 4.2.1.11) YMR323w - yeast (Saccharomyces cerevisiae) >gi|1072413|emb|CAA90841.1| (Z54141) unknown [Saccharomyces cerevisiae] Length = 437 Score = 68.7 bits (165), Expect = 9e-11 Identities = 48/132 (36%), Positives = 65/132 (48%), Gaps = 16/132 (12%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51 I + R V G +VEV++ T+ G R P + +H A R Sbjct: 3 ITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGV 62 Query: 52 --AVSEVDEIIGPELIGFD--AVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 AVS V+ IIGP LI D Q+ ID + +DGT + S +GAN L VS+ +ARAA Sbjct: 63 TKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAA 122 Query: 108 ANSKDMSLYSYI 119 A K ++LY YI Sbjct: 123 AAQKGITLYKYI 134 >gb|AAC47638.1| (U85827) enolase [Hydra cf. oligactis] Length = 173 Score = 68.7 bits (165), Expect = 9e-11 Identities = 52/149 (34%), Positives = 75/149 (49%), Gaps = 19/149 (12%) Query: 1 MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR--------- 50 M+ I I R ++ G +VEVD+ T G R A P + +H A E R Sbjct: 1 MAPITKIHAREILDSTGNPTVEVDLTTPLGTFRAAVPSGASTGIHEALELRDKDPKRYLG 60 Query: 51 ----RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIA 104 +AV V+EII P LI D +Q+ +D + E+DGT + S +GAN L VS+A++ Sbjct: 61 KGVTKAVENVNEIIAPYLISKNIDCTKQKEVDQLMIELDGTPNKSKLGANATLGVSLAVS 120 Query: 105 RAAANSKDMSLYSYIGGTFATE---LPVP 130 +A A K + LY ++ E LPVP Sbjct: 121 KAGAAQKGVPLYKHLADLAGNENLILPVP 149 >sp|O57391|ENOG_CHICK GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE) (NSE) >gi|2842531|dbj|BAA24680.1| (AB004291) gamma-subunit of enolase [Gallus gallus] Length = 434 Score = 68.7 bits (165), Expect = 9e-11 Identities = 48/146 (32%), Positives = 73/146 (49%), Gaps = 19/146 (13%) Query: 4 IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51 ++ I R ++ G +VEVD+ T +G R A P + ++ A R Sbjct: 3 VERIHAREILDSRGNPTVEVDLYTHKGMFRAAVPSGASTGIYEALELRDNDKSRFLGKGV 62 Query: 52 --AVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107 AV ++ + P ++G V+QE ID+ + E+DGTE+ S GAN L VS+A+ +A Sbjct: 63 LQAVDHINSTVAPAIVGSGLSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAG 122 Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130 A KD+ LY +I G LPVP Sbjct: 123 AAEKDVPLYRHIADLAGNSDLILPVP 148 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.318 0.139 0.385 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 121507069 Number of Sequences: 2977 Number of extensions: 5045219 Number of successful extensions: 13373 Number of sequences better than 1.0e-10: 80 Number of HSP's better than 0.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 49 Number of HSP's that attempted gapping in prelim test: 13233 Number of HSP's gapped (non-prelim): 140 length of query: 342 length of database: 189,106,746 effective HSP length: 58 effective length of query: 284 effective length of database: 154,394,500 effective search space: 43848038000 effective search space used: 43848038000 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 165 (68.7 bits)