BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0367 (eno-like) DE:enolase related (eno)
         (342 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75172 enolase related (eno) PAB0367 - Pyrococcus abyssi (s...   672  0.0
pir||F71042 hypothetical protein PH1630 - Pyrococcus horikoshii ...   594  e-169
sp|O26149|ENO_METTH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   143  2e-33
dbj|BAB07275.1| (AP001519) enolase (2-phosphoglycerate dehydrata...   109  3e-23
sp|O59605|ENO_PYRHO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   108  8e-23
sp|P33675|ENO_ZYMMO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   106  4e-22
pir||H75022 phosphopyruvate hydratase (EC 4.2.1.11) PAB1126 - Py...   106  4e-22
gb|AAD35958.1|AE001753_14 (AE001753) enolase [Thermotoga maritima]    101  1e-20
gi|11498732 enolase (eno) [Archaeoglobus fulgidus] >gi|6015092|s...   101  1e-20
sp|P42848|ENO_THEMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   101  1e-20
sp|O85348|ENO_NITEU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    99  5e-20
pir||D75251 enolase - Deinococcus radiodurans (strain R1) >gi|64...    99  7e-20
pir||A81841 phosphopyruvate hydratase (EC 4.2.1.11) NMA1495 [imp...    99  9e-20
pir||D81100 enolase NMB1285 [imported] - Neisseria meningitidis ...    99  9e-20
pir||A41835 phosphopyruvate hydratase (EC 4.2.1.11) - Bacillus s...    98  1e-19
sp|P37869|ENO_BACSU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    98  1e-19
sp|P29201|ENO_HALMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    97  3e-19
sp|P96377|ENO_MYCTU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    92  7e-18
pir||T33721 phosphopyruvate hydratase (EC 4.2.1.11) eno - Zymomo...    92  7e-18
dbj|BAA81815.1| (AB029313) enolase [Streptococcus intermedius]         92  1e-17
emb|CAC09537.1| (AL442120) enolase [Streptomyces coelicolor]           92  1e-17
sp|O66778|ENO_AQUAE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    92  1e-17
sp|Q60173|ENO_METJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    90  3e-17
sp|O69174|ENO_STAAU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    90  4e-17
sp|P48285|ENO_HELPY ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    90  4e-17
sp|Q9ZMS6|ENO_HELPJ ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    89  7e-17
sp|O30885|ENO_CAMFE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    86  5e-16
emb|CAC12011.1| (AL445065) enolase related protein [Thermoplasma...    85  1e-15
dbj|BAB07786.1| (AB046715) enolase [Desulfovibrio vulgaris]            85  1e-15
gb|AAF13454.1|AF205070_1 (AF205070) enolase [Mastigamoeba balamu...    84  2e-15
sp|Q57651|Y198_METJA HYPOTHETICAL PROTEIN MJ0198 >gi|2128174|pir...    84  2e-15
gb|AAC47644.1| (U85832) enolase [Stylochus zebra]                      83  4e-15
gb|AAF73201.1|AF152348_1 (AF152348) enolase [Trypanosoma brucei ...    82  1e-14
sp|Q9Z7A6|ENO_CHLPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    82  1e-14
sp|P42448|ENO_CAMJE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    81  2e-14
sp|P08324|ENO_ECOLI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    80  4e-14
pir||E82076 enolase VC2447 [imported] - Vibrio cholerae (group O...    80  4e-14
emb|CAA57795.1| (X82400) enolase [Escherichia coli]                    80  4e-14
emb|CAB94910.1| (AJ401152) enolase [Enterococcus faecalis]             80  5e-14
gb|AAC47645.1| (U85834) enolase [Tubularia sp.]                        78  2e-13
sp|O84591|ENO_CHLTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    77  3e-13
pir||A72477 probable enolase APE2458 - Aeropyrum pernix (strain ...    76  4e-13
sp|Q27527|ENO_CAEEL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    76  7e-13
sp|P40370|ENO1_SCHPO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2...    75  9e-13
gb|AAC43380.1| (U13756) enolase [Helicobacter pylori]                  75  9e-13
emb|CAB96125.1| (AJ272111) enolase [Euglena gracilis]                  75  9e-13
gb|AAC47639.1| (U85833) enolase [Hymenolepis diminuta]                 75  1e-12
sp|P15007|ENO_DROME ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    74  2e-12
gb|AAF51344.1| (AE003585) Eno gene product [Drosophila melanogas...    74  2e-12
sp|P74934|ENO_TREPA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    73  4e-12
sp|P07323|ENOG_RAT GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LY...    73  5e-12
emb|CAC16971.1| (AL450350) enolase [Streptomyces coelicolor]           73  5e-12
sp|P43806|ENO_HAEIN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    73  5e-12
sp|P08734|ENO_XENLA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    73  5e-12
sp|O52191|ENO_STRTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    73  5e-12
emb|CAB94039.1| (AL358652) enolase [Leishmania major]                  72  8e-12
pir||S43113 phosphopyruvate hydratase (EC 4.2.1.11) - fungus  (C...    72  1e-11
sp|P07322|ENOB_CHICK BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-L...    72  1e-11
sp|P42040|ENO_CLAHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    72  1e-11
pir||T39737 enolase - fission yeast (Schizosaccharomyces pombe) ...    71  1e-11
pir||JC1039 phosphopyruvate hydratase (EC 4.2.1.11) - rat              71  2e-11
gb|AAB87890.1| (AF025805) enolase [Drosophila pseudoobscura]           71  2e-11
gb|AAB87891.1| (AF025806) enolase [Drosophila subobscura]              71  2e-11
pir||A23850 phosphopyruvate hydratase (EC 4.2.1.11), skeletal mu...    71  2e-11
gb|AAD45339.1|AF159529_1 (AF159529) enolase [Trypanosoma brucei]       71  2e-11
gb|AAF36733.1| (AC016662) putative enolase; 31277-33713 [Arabido...    71  2e-11
emb|CAA31512.1| (X13120) neurone-specific enolase [Homo sapiens]...    70  3e-11
pir||E81654 enolase TC0876 [imported] - Chlamydia muridarum (str...    70  3e-11
sp|P09104|ENOG_HUMAN GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-...    70  3e-11
gi|7305027 enolase 2, gamma neuronal [Mus musculus] >gi|119348|s...    70  4e-11
gb|AAC47640.1| (U85826) enolase [Haematoloechus sp.]                   70  4e-11
gb|AAC47641.1| (U85828) enolase [Lacistorhynchus tenuis]               70  4e-11
gb|AAC46289.1| (AF000366) enolase homolog [Borrelia burgdorferi]       70  4e-11
sp|O51312|ENO_BORBU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    70  4e-11
sp|P42894|ENO_NEOFR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...    69  5e-11
gi|5803011 enolase 2, (gamma, neuronal); Enolase-2, gamma, neuro...    69  7e-11
sp|P30575|ENO1_CANAL ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) ...    69  9e-11
gi|6323985 Ymr323wp [Saccharomyces cerevisiae] >gi|1706698|sp|P4...    69  9e-11
gb|AAC47638.1| (U85827) enolase [Hydra cf. oligactis]                  69  9e-11
sp|O57391|ENOG_CHICK GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-...    69  9e-11

>pir||C75172 enolase related (eno) PAB0367 - Pyrococcus abyssi (strain Orsay)
           >gi|5457968|emb|CAB49458.1| (AJ248284) enolase related
           (eno) [Pyrococcus abyssi]
           Length = 342
           
 Score =  672 bits (1716), Expect = 0.0
 Identities = 342/342 (100%), Positives = 342/342 (100%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEII 60
           MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEII
Sbjct: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEII 60

Query: 61  GPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIG 120
           GPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIG
Sbjct: 61  GPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIG 120

Query: 121 GTFATELPVPIIQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKASE 180
           GTFATELPVPIIQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKASE
Sbjct: 121 GTFATELPVPIIQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKASE 180

Query: 181 SVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFIDG 240
           SVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFIDG
Sbjct: 181 SVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFIDG 240

Query: 241 EYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADDTFP 300
           EYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADDTFP
Sbjct: 241 EYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADDTFP 300

Query: 301 HLALGLRCPAMLISWNSVEKINELNRIAEELGERGRIITFEE 342
           HLALGLRCPAMLISWNSVEKINELNRIAEELGERGRIITFEE
Sbjct: 301 HLALGLRCPAMLISWNSVEKINELNRIAEELGERGRIITFEE 342


>pir||F71042 hypothetical protein PH1630 - Pyrococcus horikoshii
           >gi|3258059|dbj|BAA30742.1| (AP000006) 341aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 341
           
 Score =  594 bits (1515), Expect = e-169
 Identities = 291/342 (85%), Positives = 322/342 (94%), Gaps = 1/342 (0%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEII 60
           MSVIQNIIGR+ VLRGG YSVEVDVATDEGFGRF SPI++NPMLHIAEARRAVSEVDEII
Sbjct: 1   MSVIQNIIGRIAVLRGGKYSVEVDVATDEGFGRFTSPIDDNPMLHIAEARRAVSEVDEII 60

Query: 61  GPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIG 120
           GPELIGFDA EQELIDSYLWEIDGTEDFSHIGANTALAVS AIA+AAANS+DM LYSYIG
Sbjct: 61  GPELIGFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSTAIAKAAANSRDMPLYSYIG 120

Query: 121 GTFATELPVPIIQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKASE 180
           GTFATELPVP++ FA D+ F+YY++V+DLLEVTDI+DA NKI  E+  ++++E LSKASE
Sbjct: 121 GTFATELPVPVLSFAQDDMFDYYLVVKDLLEVTDIIDATNKI-REIVKEINLENLSKASE 179

Query: 181 SVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFIDG 240
            VG+ELGLEVALGI MK+E++IE VLN+VED NVAYIKP+GPPELFLELIAGTHGVFIDG
Sbjct: 180 DVGVELGLEVALGIGMKKEMDIEKVLNLVEDYNVAYIKPIGPPELFLELIAGTHGVFIDG 239

Query: 241 EYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADDTFP 300
           EYLFR N++LDRRYYNALSIKPINLGTLTDLYNFVNDVK+EKITPILAEAKYEPAD+TFP
Sbjct: 240 EYLFRTNSVLDRRYYNALSIKPINLGTLTDLYNFVNDVKAEKITPILAEAKYEPADETFP 299

Query: 301 HLALGLRCPAMLISWNSVEKINELNRIAEELGERGRIITFEE 342
           H+ALGLRCPAMLISW+S+EKINELNRIAEELGERGRIITFEE
Sbjct: 300 HIALGLRCPAMLISWSSIEKINELNRIAEELGERGRIITFEE 341


>sp|O26149|ENO_METTH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436881|pir||A69156 enolase -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621078|gb|AAB84550.1| (AE000796) enolase
           [Methanobacterium thermoautotrophicum]
           Length = 416
           
 Score =  143 bits (358), Expect = 2e-33
 Identities = 129/405 (31%), Positives = 190/405 (46%), Gaps = 76/405 (18%)

Query: 2   SVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPI------EENPMLHIAEARRAVSE 55
           S+I+++  R ++   G  +VEVDV T  GFGR A+P        E            ++E
Sbjct: 3   SIIEDVRVRKILDSRGNPTVEVDVITWNGFGRAAAPSGASTGSREVAAFPSGGVDEIITE 62

Query: 56  VDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSL 115
           V++II  ELIG DAV+ + ID  L EIDGTE+ S +G NT +AVS+A A+AAA+S +M L
Sbjct: 63  VEDIISSELIGMDAVDLQDIDLVLKEIDGTENLSSLGGNTVVAVSMATAKAAASSYNMPL 122

Query: 116 YSYIGGTFATELPVPIIQFASD--------ENFEYYILV----RDLLEVTDIVDAVNKII 163
           Y ++GG  AT +P P+    +          + + +++V     D+ E      AV+K I
Sbjct: 123 YRFLGGNLATSIPYPLGNMINGGAHAGKNAPDIQEFLVVPVGAEDITEAVFANAAVHKRI 182

Query: 164 SEV----------------------GNKVSIEELSKASESVGMELGLEVALGIKMKR--- 198
            E+                       N  ++E  + A E V  ELG+EV   + +     
Sbjct: 183 RELIQKKDPSFAGGKGDEGGWVPSLSNGDALEIQATACEEVTDELGVEVRPSLDLAASEF 242

Query: 199 ---ELE----------------IEDVLNIVEDNNVAYIK-PL--GPPELFLEL--IAGTH 234
              E+E                IE V  I+E  ++ Y++ PL  G  E F EL  + G  
Sbjct: 243 WDPEIEKYVYRQENVQKDTGEQIEFVKEIIETYDMYYVEDPLHEGDLEGFAELTSLVGDR 302

Query: 235 GVFIDGEYLFRANNILDRRYY-----NALSIKPINLGTLTDLYNFVNDVKSEKITPILAE 289
              I G+ +F  N  + R        NA+ IKP  +GTLTD Y  V      + TP+++ 
Sbjct: 303 -CMICGDDIFVTNREILREGIEMGAANAIIIKPNQIGTLTDTYLTVKLALENRYTPVVSH 361

Query: 290 AKYEPADDTFPHLALGLRCPAM---LISWNSVEKINELNRIAEEL 331
              E  DDT  HLA+    P +    I    + K+NEL RI EE+
Sbjct: 362 RSGETTDDTIAHLAVAFGAPLIKTGAIGGERIAKLNELIRIQEEI 406


>dbj|BAB07275.1| (AP001519) enolase (2-phosphoglycerate dehydratase) [Bacillus
           halodurans]
           Length = 429
           
 Score =  109 bits (271), Expect = 3e-23
 Identities = 112/414 (27%), Positives = 185/414 (44%), Gaps = 83/414 (20%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51
           M++I ++  R V+   G  +VEV+V  + G  GR   P   +   + A   R        
Sbjct: 1   MTIITDVYAREVLDSRGNPTVEVEVYLESGAMGRALVPSGASTGEYEAVELRDGGERFLG 60

Query: 52  -----AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARA 106
                AV  V+E+I PELIGFDA++Q  ID ++ E+DGTE+   +GAN  L VS+A+ARA
Sbjct: 61  KGVLKAVENVNEVIAPELIGFDALDQIGIDQHMIELDGTENKGKLGANAILGVSMAVARA 120

Query: 107 AANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLEV 152
           AAN+ D+ LY Y+GG  A +LPVP++        +D N    E+ I+       ++ L  
Sbjct: 121 AANALDLPLYVYLGGFNAKQLPVPMMNIINGGEHADNNVDIQEFMIMPVGAESFKEALRT 180

Query: 153 -TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGI 194
            T+I  ++ K++   G                 N+ +++ + +A E  G   G +V L +
Sbjct: 181 GTEIFHSLKKVLKSKGYNTAVGDEGGFAPNLSSNEEALQTIIEAIEQAGYTPGEQVKLAM 240

Query: 195 KM-----------KRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGT-------HGV 236
            +           K  L  E  + +  +  VA+ + L      + +  G        H +
Sbjct: 241 DVASSELYNKEDGKYHLSGEGKV-LSSEEMVAFYEELVAKYPIISIEDGLDENDWEGHKM 299

Query: 237 FID---------GEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDVKSEK 282
             D         G+ LF  N       +++   N++ IK   +GTLT+ ++ +   K   
Sbjct: 300 LTDRLGDKVQLVGDDLFVTNTKKLAQGIEQGVGNSILIKVNQIGTLTETFDAIEMAKRAG 359

Query: 283 ITPILAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELG 332
            T +++    E  D T   +A+      +     S    V K N+L RI +ELG
Sbjct: 360 YTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELG 413


>sp|O59605|ENO_PYRHO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436873|pir||F71209 probable
           phosphoglycerate dehydratase - Pyrococcus horikoshii
           >gi|3258386|dbj|BAA31069.1| (AP000007) 428aa long
           hypothetical phosphoglycerate dehydratase [Pyrococcus
           horikoshii]
           Length = 428
           
 Score =  108 bits (268), Expect = 8e-23
 Identities = 116/407 (28%), Positives = 176/407 (42%), Gaps = 80/407 (19%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAE-------------AR 50
           I  I+ R ++   G  +VEVDV T    GR A P   +   H A               R
Sbjct: 7   ITAIVAREILDSRGNPTVEVDVHTPIAMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVR 66

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           RAV  V++II PELIG D   Q  ID  L E+DGTE+ S++GAN  LAVS+A+A+AAANS
Sbjct: 67  RAVENVNKIIAPELIGMDVRWQREIDKLLIELDGTENKSNLGANAILAVSLAVAKAAANS 126

Query: 111 KDMSLYSYIGGTFATELPVPI-------IQFASDENFE---------------------- 141
            ++ LY Y+GG  A  LPVP+       +   ++ +F+                      
Sbjct: 127 LELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNELDFQEFMIMPIGASSFREAIRWVSET 186

Query: 142 YYILVRDLL---------------------EVTDIVDAVNKIISEVGNKVSIEELSKASE 180
           Y++L R ++                     EVT+ +DA+ K I E G K   +E++ A +
Sbjct: 187 YHVLKRVIMGKYGKNAVNVGDEGGFAPPMKEVTEPLDALIKAIEEAGYKPG-DEIALAID 245

Query: 181 SVGMEL---GLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTH--- 234
           +   E    G  +  G +  RE  ++    +V    +  I+     E +   +  T+   
Sbjct: 246 AASSEFFKDGKYIVGGKEYTREELLDLYKELVSTYPIVSIEDPFHEEDWEGFVMITNELG 305

Query: 235 -GVFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILA 288
             + I G+ LF     R    ++    NAL +K   +GTLT+  +          + I++
Sbjct: 306 KKIQIVGDDLFVTNPRRLKKGIELGAANALLLKVNQIGTLTEAMDAAYTAFRAGYSVIVS 365

Query: 289 EAKYEPADDTFPHLALGLRCPAMLIS----WNSVEKINELNRIAEEL 331
               E  D T   LA+ L    +        +   K N+L RI EEL
Sbjct: 366 HRSGETEDTTIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 412


>sp|P33675|ENO_ZYMMO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|538726|pir||A45732 phosphopyruvate
           hydratase (EC 4.2.1.11) - Zymomonas mobilis
           >gi|155581|gb|AAA27686.1| (M99380) enolase [Zymomonas
           mobilis]
           Length = 428
           
 Score =  106 bits (262), Expect = 4e-22
 Identities = 107/413 (25%), Positives = 181/413 (42%), Gaps = 81/413 (19%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51
           M+ I +I GR VV   G  +VEVDV  ++G FGR A P   +  +H A   R        
Sbjct: 1   MTAIVSIHGRQVVDSRGNPTVEVDVTLEDGSFGRAAVPSGASTGVHEAVELRDGDKTRWG 60

Query: 52  ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                 AV  V+  I   +IG +A +QELID  + ++DGT +    GAN  L VS+A+A+
Sbjct: 61  GKGVTKAVHAVNNEIANAIIGLEAEDQELIDQTMIKLDGTPNKGKFGANAILGVSLAVAK 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFASDE-------NFEYYIL-------VRDLLE 151
           AAA ++ + LY Y+GGT A  LPVP++   +         +F+ +++       + + + 
Sbjct: 121 AAAEARGLPLYRYVGGTAAHVLPVPMMNIVNGGMHADNPIDFQEFMIAPVGASSINEAVR 180

Query: 152 V-TDIVDAVNKIISEVGNKVS---------------------IEELSKASESVGME--LG 187
           + T++   + K +S  G   +                     ++ +SKA    G +  + 
Sbjct: 181 IGTEVFHTLKKELSAKGMNTNVGDEGGFAPSLDSASSALDFIVDSISKAGYKPGEDVFIA 240

Query: 188 LEVALGIKMKRELEIEDV----------------LNIVEDNNVAYIKPLGPPEL-FLELI 230
           L+ A      ++  I D+                + +     +  I+ L   +  F +++
Sbjct: 241 LDAASSEFYNKDQNIYDLKGEGRKLTSAQLVDYYVELCGKYPIYSIEDLAEDDFEFWKIL 300

Query: 231 AGTHG--VFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKI 283
               G  V + G+ LF     R ++ ++R   N+L +K   +G+L++    VN       
Sbjct: 301 TEKLGDKVQLVGDDLFVTNVKRLSDGIERGIANSLLVKFNQIGSLSETLAAVNMANDASY 360

Query: 284 TPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELG 332
           TP+++    E  D T   LA+   C       L     + K N+L RI EELG
Sbjct: 361 TPVMSHRSVETEDTTIADLAVATNCGQIKTGSLCRSERIAKYNQLMRIEEELG 413


>pir||H75022 phosphopyruvate hydratase (EC 4.2.1.11) PAB1126 - Pyrococcus abyssi
           (strain Orsay) >gi|5459136|emb|CAB50622.1| (AJ248288)
           enolase (EC 4.2.1.11) (eno) [Pyrococcus abyssi]
           Length = 430
           
 Score =  106 bits (262), Expect = 4e-22
 Identities = 88/259 (33%), Positives = 130/259 (49%), Gaps = 32/259 (12%)

Query: 7   IIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAE-------------ARRAV 53
           +I R ++   G  +VEVDV T    GR A P   +   H A               RRAV
Sbjct: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVRRAV 71

Query: 54  SEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDM 113
             V++II PEL+G D   Q  ID  L E+DGTE+ S++GAN  LAVS+A+A+AAAN+ ++
Sbjct: 72  ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131

Query: 114 SLYSYIGGTFATELPVPI-------IQFASDENFEYYILVRDLLEVTDIVDAVNKIIS-- 164
            LY Y+GG  A  LPVP+       +   +D +F+ ++++   +      +A+  +    
Sbjct: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMP--IGANSFREAIRWVSETY 189

Query: 165 EVGNKVSIEELSKASESVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPPE 224
            V  KV  E+  K + +VG E G        MK   E  DVL  ++    A  KP    E
Sbjct: 190 HVLKKVIAEKYGKNAVNVGDEGG----FAPPMKEVTEPLDVL--IKAIEEAGYKP--GEE 241

Query: 225 LFLELIAGTHGVFIDGEYL 243
           + L L A +   + DG+Y+
Sbjct: 242 IALALDAASSEFYKDGKYI 260


>gb|AAD35958.1|AE001753_14 (AE001753) enolase [Thermotoga maritima]
           Length = 427
           
 Score =  101 bits (249), Expect = 1e-20
 Identities = 101/348 (29%), Positives = 156/348 (44%), Gaps = 65/348 (18%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           +AV  V+E I P LIG +A +Q L+D  L E+DGTE+ S +GAN  LAVS+A+ARAAAN 
Sbjct: 65  KAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAAANY 124

Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLEV-TDI 155
             + LY Y+GG  A  LPVP++        +D N    E+ I+       R+ L    +I
Sbjct: 125 LGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAGAEI 184

Query: 156 VDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGIKMK- 197
              + KI+ E G                 N+ +I+ L +A E  G + G EV + +    
Sbjct: 185 FHTLKKILHEAGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIALDCAA 244

Query: 198 ---------------RELEIEDVLNIVEDNNVAY-IKPLGPP------ELFLELIAGT-H 234
                           E   E ++   E+    Y I  +  P      + F+E      +
Sbjct: 245 SSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFTKRVGN 304

Query: 235 GVFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAE 289
            V I G+ L+     R +  ++ +  N++ IK   +GT+T+  + V   +   +T I++ 
Sbjct: 305 KVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMTAIISH 364

Query: 290 AKYEPADDTFPHLAL----GLRCPAMLISWNSVEKINELNRIAEELGE 333
              E  D     LA+    G      L     + K N+L RI EELG+
Sbjct: 365 RSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGK 412


>gi|11498732 enolase (eno) [Archaeoglobus fulgidus]
           >gi|6015092|sp|O29133|ENO_ARCFU ENOLASE
           (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436882|pir||C69391 enolase (eno)
           homolog - Archaeoglobus fulgidus
           >gi|2649457|gb|AAB90112.1| (AE001026) enolase (eno)
           [Archaeoglobus fulgidus]
           Length = 366
           
 Score =  101 bits (249), Expect = 1e-20
 Identities = 90/344 (26%), Positives = 156/344 (45%), Gaps = 62/344 (18%)

Query: 55  EVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMS 114
           E++E +   +IG    +QE +D  L E+DGT++FS IG N A+  S+A+A+AAA    + 
Sbjct: 23  EIEEEVSKAIIGMSVFDQESVDEALRELDGTDNFSRIGGNFAITASLAVAKAAAEILGLP 82

Query: 115 LYSYIGGTFATELPVPIIQF--------ASDENFEYYIL---VRDLLEVTDIVDAVNKII 163
           LY+Y+GG FA ELP P+            S    E+ ++    +   E      AV+K +
Sbjct: 83  LYAYVGGVFAKELPYPLGNVIGGGRHAEGSTSIQEFLVIPVGAKTFFEAQRANAAVHKQL 142

Query: 164 --------------------SEVGNKVSIEELSKASESVGMELGLEVALGI--------- 194
                               +++ ++ + E LS+A + V  ELG++V +GI         
Sbjct: 143 KKIFKERGIFAAKGDEGAWAAQISDEQAFEILSEAIQRVEDELGVKVRMGIDVAATELWD 202

Query: 195 ---------KMKRELEIEDVLNIVEDNNVAYIK-PLGPPEL--FLELIAGTHGVFIDGEY 242
                    K+  E +I  +  + +  ++ YI+ PL   +   F EL        + G+ 
Sbjct: 203 GERYVYSDRKLTTEEQIAYMAELADRYDLLYIEDPLHEKDFEGFAELTKQVK-CMVCGDD 261

Query: 243 LFRANNILDRR-----YYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADD 297
           +F  N  + ++       N + IKP   GTL+     V   K    + +++    E  D+
Sbjct: 262 IFVTNPEIIKKGIEVGAANTVLIKPNQNGTLSGTAKAVKIAKDNGYSVVVSHRSGETEDE 321

Query: 298 TFPHLALGLRCPAM---LISWNSVEKINELNRIAEELGERGRII 338
           T  HLA+      +   ++    + K+NEL RI EEL ++ R++
Sbjct: 322 TLAHLAVAFNAKLIKTGVVGGERISKLNELIRI-EELMDKPRMV 364


>sp|P42848|ENO_THEMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436890|pir||G72323 phosphopyruvate
           hydratase (EC 4.2.1.11) - Thermotoga maritima (strain
           MSB8)
           Length = 429
           
 Score =  101 bits (249), Expect = 1e-20
 Identities = 101/348 (29%), Positives = 156/348 (44%), Gaps = 65/348 (18%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           +AV  V+E I P LIG +A +Q L+D  L E+DGTE+ S +GAN  LAVS+A+ARAAAN 
Sbjct: 67  KAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAAANY 126

Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLEV-TDI 155
             + LY Y+GG  A  LPVP++        +D N    E+ I+       R+ L    +I
Sbjct: 127 LGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAGAEI 186

Query: 156 VDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGIKMK- 197
              + KI+ E G                 N+ +I+ L +A E  G + G EV + +    
Sbjct: 187 FHTLKKILHEAGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIALDCAA 246

Query: 198 ---------------RELEIEDVLNIVEDNNVAY-IKPLGPP------ELFLELIAGT-H 234
                           E   E ++   E+    Y I  +  P      + F+E      +
Sbjct: 247 SSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFTKRVGN 306

Query: 235 GVFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAE 289
            V I G+ L+     R +  ++ +  N++ IK   +GT+T+  + V   +   +T I++ 
Sbjct: 307 KVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMTAIISH 366

Query: 290 AKYEPADDTFPHLAL----GLRCPAMLISWNSVEKINELNRIAEELGE 333
              E  D     LA+    G      L     + K N+L RI EELG+
Sbjct: 367 RSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGK 414


>sp|O85348|ENO_NITEU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|3493583|gb|AAC33442.1| (AF061753)
           enolase; 2-phospho-D-glycerate hydrolase [Nitrosomonas
           europaea]
           Length = 428
           
 Score = 99.5 bits (244), Expect = 5e-20
 Identities = 113/416 (27%), Positives = 176/416 (42%), Gaps = 86/416 (20%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP------IEENPMLHIAEARR-- 51
           MS I ++I R ++   G  ++E DV  + G  GR + P        E   L   +A+R  
Sbjct: 1   MSAIVDVIAREIIDSRGNPTIEADVLLESGVLGRASVPSGASVGTREAVELRDGDAQRYY 60

Query: 52  ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                 AV  V+  I   ++G DA+EQ  ID  L E+DG+E+ S +GAN  LAVS+A+A+
Sbjct: 61  GKGVLKAVESVNGEISETIMGLDAMEQCFIDKTLIELDGSENKSRLGANAILAVSLAVAK 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFASD----------ENF--------------- 140
           AAA    + LY Y+GG  A  LPVP++   +           + F               
Sbjct: 121 AAAEESGLPLYRYLGGINAKWLPVPMMNLVNGGVHANNRLDMQEFMIIPLGLPNLREAVR 180

Query: 141 ---EYYILVRDLLE----VTDIVDAVNKIISEVGNKVSIEELSKASESVGMELGLEVALG 193
              E +  +R LL      T + D      S   N+ ++  + +A +  G + G EVA+G
Sbjct: 181 CGAEVFSTLRTLLNKRNLPTTVGDEGGFAPSFARNEEALALIVQAIDEAGYQPGSEVAIG 240

Query: 194 I---------KMKRELEIEDVLNIVEDNNVAYIK------PLGPPE------------LF 226
           +         + K  L++ D L +     V Y+       P+   E            L 
Sbjct: 241 VDCASSEFFREGKYHLDV-DGLGLTSAQFVDYLATWVEKYPIISIEDGMSEQDWEGWGLL 299

Query: 227 LELIAGTHGVFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDVKSE 281
            E +  T  V + G+ +F  N       + R   N++ IK   +GTLT+  N +   K  
Sbjct: 300 TERLGKT--VQLVGDDVFVTNTRILKEGISRNIANSILIKINQIGTLTETLNAIEMAKCA 357

Query: 282 KITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333
             T I++    E  D T   +A+           L   + + K N+L RI E+LGE
Sbjct: 358 GYTAIVSHRSGETEDTTIADIAVATNALQIKTGSLSRSDRLAKYNQLLRIEEDLGE 413


>pir||D75251 enolase - Deinococcus radiodurans (strain R1)
           >gi|6460466|gb|AAF12173.1|AE002092_11 (AE002092) enolase
           [Deinococcus radiodurans]
           Length = 422
           
 Score = 99.1 bits (243), Expect = 7e-20
 Identities = 109/415 (26%), Positives = 175/415 (41%), Gaps = 89/415 (21%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASPIEENPMLHIA-------------EA 49
           I+ +I R V+   G  +VE +V  D GF GR   P   +   H A               
Sbjct: 3   IEKVIAREVLDSRGNPTVEAEVHLDSGFSGRAIVPSGASTGSHEALELRDGGERYMGKGV 62

Query: 50  RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109
            RAV  V E +GP LIG DA EQ  ID  L ++DGT +  ++G N  LAVS+A ARAAA 
Sbjct: 63  ERAVQNVREALGPALIGMDASEQAAIDKALMDVDGTSNKGNMGGNAILAVSLATARAAAA 122

Query: 110 SKDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV-------RDLLEV-TD 154
             D+ LY Y+GG+ A  LPVP++          +  +F+ ++++       R+ L    +
Sbjct: 123 ELDIPLYRYLGGSNAKTLPVPMMNVINGGAHADNSVDFQEFMVMPVGAPSFREALRYGAE 182

Query: 155 IVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGI--- 194
               + K++S  G                 N+ ++E L +A +  G E G ++ + +   
Sbjct: 183 TFHHLKKVLSGRGYNTNVGDEGGFAPDLKSNEEALEVLLEAIQQAGYEPGKDICIALDPA 242

Query: 195 -------------KMKRELEIEDVLNIVEDNNVAYIKPL-------------GPPELFLE 228
                           R L  +++++   D    Y  P+             G   L  +
Sbjct: 243 VTELYKDGQYHLESEGRVLSSDEMIDFWADWTSRY--PIVSIEDGLAEDDWDGWERLTAK 300

Query: 229 LIAGTHGVFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKI 283
           + A T  V   G+ LF     R    +DR+  NA+ +K   +G+LT+  + +   K    
Sbjct: 301 VGAKTQLV---GDDLFVTNPERLQQGIDRKVGNAILVKVNQIGSLTESMDAIELAKRHHY 357

Query: 284 TPILAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELGER 334
             I++    E  D     LA+      +     S    + K N+L RI ++LG+R
Sbjct: 358 GTIISHRSGESEDAFIADLAVATNAGQIKTGSASRSDRIAKYNQLLRIEDQLGDR 412


>pir||A81841 phosphopyruvate hydratase (EC 4.2.1.11) NMA1495 [imported] -
           Neisseria meningitidis (group A strain Z2491)
           >gi|7380143|emb|CAB84728.1| (AL162756) enolase
           [Neisseria meningitidis Z2491]
           Length = 428
           
 Score = 98.7 bits (242), Expect = 9e-20
 Identities = 110/416 (26%), Positives = 176/416 (41%), Gaps = 86/416 (20%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP----IEENPMLHIAEARR---- 51
           MS I +I  R ++   G  +VE DV  + G  GR A P      +   L + +  +    
Sbjct: 1   MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYS 60

Query: 52  ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                 AV  V+  I   LIG DA EQ  ID  + E+DGTE+  ++GAN  LAVS+A+AR
Sbjct: 61  GKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVAR 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV-------RDLLE 151
           AAA    + LY Y+GG     LPVP++          +  N + ++++       R+ L 
Sbjct: 121 AAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALR 180

Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193
              +I  A+ K+    G                 +K +++ + +A+E+ G + G +V   
Sbjct: 181 CGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFA 240

Query: 194 IKM---------KRELEIED-----------VLNIVEDNNVAYIKPLGPPE-------LF 226
           +           K  LE E            +  +V +  +  I+  G  E       L 
Sbjct: 241 LDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIED-GMDENDWEGWKLL 299

Query: 227 LELIAGTHGVFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSE 281
            E + G   V + G+ LF  N       +++   NAL +K   +GTL++    V+  K  
Sbjct: 300 TEKLGGK--VQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRN 357

Query: 282 KITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333
           +   +++    E  D T   LA+   C       L   + + K N+L RI EEL E
Sbjct: 358 RYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAE 413


>pir||D81100 enolase NMB1285 [imported] - Neisseria meningitidis (group B strain
           MD58) >gi|7226525|gb|AAF41661.1| (AE002477) enolase
           [Neisseria meningitidis MC58]
           Length = 428
           
 Score = 98.7 bits (242), Expect = 9e-20
 Identities = 110/416 (26%), Positives = 176/416 (41%), Gaps = 86/416 (20%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP----IEENPMLHIAEARR---- 51
           MS I +I  R ++   G  +VE DV  + G  GR A P      +   L + +  +    
Sbjct: 1   MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYS 60

Query: 52  ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                 AV  V+  I   LIG DA EQ  ID  + E+DGTE+  ++GAN  LAVS+A+AR
Sbjct: 61  GKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVAR 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV-------RDLLE 151
           AAA    + LY Y+GG     LPVP++          +  N + ++++       R+ L 
Sbjct: 121 AAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALR 180

Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193
              +I  A+ K+    G                 +K +++ + +A+E+ G + G +V   
Sbjct: 181 CGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFA 240

Query: 194 IKM---------KRELEIED-----------VLNIVEDNNVAYIKPLGPPE-------LF 226
           +           K  LE E            +  +V +  +  I+  G  E       L 
Sbjct: 241 LDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIED-GMDENDWEGWKLL 299

Query: 227 LELIAGTHGVFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSE 281
            E + G   V + G+ LF  N       +++   NAL +K   +GTL++    V+  K  
Sbjct: 300 TEKLGGR--VQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRN 357

Query: 282 KITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333
           +   +++    E  D T   LA+   C       L   + + K N+L RI EEL E
Sbjct: 358 RYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAE 413


>pir||A41835 phosphopyruvate hydratase (EC 4.2.1.11) - Bacillus subtilis
           >gi|460259|gb|AAA21681.1| (L29475) enolase [Bacillus
           subtilis]
           Length = 430
           
 Score = 98.3 bits (241), Expect = 1e-19
 Identities = 113/415 (27%), Positives = 177/415 (42%), Gaps = 82/415 (19%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51
           M  I ++  R V+   G  +VEV+V T+ G FGR   P   +   + A   R        
Sbjct: 1   MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGQYEAVELRDGDKDRYL 60

Query: 52  ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                 AV+ V+EII PEL+GFD  EQ  ID  L E+DGTE+   +GAN  L VS+A AR
Sbjct: 61  GKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACAR 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLE 151
           AAA+   + LY Y+GG  +  LPVP++        +D N    E+ I+       R+ L 
Sbjct: 121 AAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALR 180

Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193
           +   I  ++  ++S  G                 N+ +++ + +A E  G + G EV L 
Sbjct: 181 MGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLA 240

Query: 194 IKM-----------KRELEIEDVLNIVEDNNVAYIKPLGP-PELFLE------------L 229
           +             K  L  E V+    +    Y + +   P + +E            L
Sbjct: 241 MDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKL 300

Query: 230 IAGTHG--VFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDVKSEK 282
           +    G  V + G+ LF  N       +     N++ IK   +GTLT+ ++ +   K   
Sbjct: 301 LTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAG 360

Query: 283 ITPILAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELGE 333
            T +++    E  D T   +A+      +     S    V K N+L RI ++L E
Sbjct: 361 YTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAE 415


>sp|P37869|ENO_BACSU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436878|pir||B69620 phosphopyruvate
           hydratase (EC 4.2.1.11) [validated] - Bacillus subtilis
           >gi|2635903|emb|CAB15395.1| (Z99121) enolase [Bacillus
           subtilis]
           Length = 430
           
 Score = 97.9 bits (240), Expect = 1e-19
 Identities = 113/415 (27%), Positives = 177/415 (42%), Gaps = 82/415 (19%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51
           M  I ++  R V+   G  +VEV+V T+ G FGR   P   +   + A   R        
Sbjct: 1   MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYL 60

Query: 52  ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                 AV+ V+EII PEL+GFD  EQ  ID  L E+DGTE+   +GAN  L VS+A AR
Sbjct: 61  GKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACAR 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLE 151
           AAA+   + LY Y+GG  +  LPVP++        +D N    E+ I+       R+ L 
Sbjct: 121 AAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALR 180

Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193
           +   I  ++  ++S  G                 N+ +++ + +A E  G + G EV L 
Sbjct: 181 MGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLA 240

Query: 194 IKM-----------KRELEIEDVLNIVEDNNVAYIKPLGP-PELFLE------------L 229
           +             K  L  E V+    +    Y + +   P + +E            L
Sbjct: 241 MDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKL 300

Query: 230 IAGTHG--VFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDVKSEK 282
           +    G  V + G+ LF  N       +     N++ IK   +GTLT+ ++ +   K   
Sbjct: 301 LTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAG 360

Query: 283 ITPILAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELGE 333
            T +++    E  D T   +A+      +     S    V K N+L RI ++L E
Sbjct: 361 YTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAE 415


>sp|P29201|ENO_HALMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|68311|pir||NOHSM phosphopyruvate
           hydratase (EC 4.2.1.11) - Haloarcula marismortui
           >gi|148781|gb|AAA73101.1| (M76567) 2-phosphoglycerate
           dehydratase [Haloarcula marismortui]
           Length = 400
           
 Score = 97.1 bits (238), Expect = 3e-19
 Identities = 107/397 (26%), Positives = 176/397 (43%), Gaps = 68/397 (17%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIA---EARRAVSEV 56
           M++I +I  R V+   G  +VE DV T+ G FGR  +P   +   + A    A  A+++ 
Sbjct: 1   MTLITDIRLRRVLDSRGNATVEADVLTESGGFGRGKAPSGASTGEYEAIELPANEAIAKA 60

Query: 57  DEIIGPELIG-FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSL 115
            E   P LIG   A  Q  +D+ L   DGT+DFS IGAN+A+A+S+A A+A A+     L
Sbjct: 61  REEALPRLIGEVHAGNQRDVDTALHAADGTDDFSGIGANSAVAISMAAAKAGADVLGAPL 120

Query: 116 YSYIGGTF-ATELPVPIIQFASDENFEYYILVRDLL-------EVTDIVDA-------VN 160
           Y ++GGTF   E P P+      E+      +++ L        V + V A       V+
Sbjct: 121 YQHLGGTFRGNEYPTPLGNIIGGEHAADATNIQEFLAAPVGAPSVEEAVFANAAVHQEVH 180

Query: 161 KIISE----------------VGNKVSIEELSKASESVGMELGLEVALGIKMKR------ 198
            I+++                V +  + E + +A E+V  + G  ++ G+ + R      
Sbjct: 181 DILADRDLPAGKGDEGAWAPSVSDDEAFEIMDEAVETVADDFGFAISFGLDVARAELYDD 240

Query: 199 --------------ELEIEDVLNIVEDNNVAYIK-PLGPP--ELFLELIAGTHG-VFIDG 240
                         E +IE +   VE+ ++ Y++ PL     E F +L A       + G
Sbjct: 241 EADGYVYDDGVKSTEEQIEYIAGKVEEYDLVYVEDPLDENDYEAFADLTAQVGDQTLVCG 300

Query: 241 EYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPA 295
           + LF     R    ++    N++ IKP  +GTLTD  + +    +     +++    E  
Sbjct: 301 DDLFVTNVERLQAGINADAGNSILIKPNQIGTLTDAVDAIELATASGYESVVSHRSGETE 360

Query: 296 DDTFPHLALGLRCPAM---LISWNSVEKINELNRIAE 329
           D T  HLA+    P +    +      K+NEL RI +
Sbjct: 361 DTTIAHLAVATDAPFIKTGAVGGERTAKLNELIRIED 397


>sp|P96377|ENO_MYCTU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436874|pir||B70623 probable enolase -
           Mycobacterium tuberculosis (strain H37RV)
           >gi|1870005|emb|CAB06856.1| (Z92539) eno [Mycobacterium
           tuberculosis]
           Length = 429
           
 Score = 92.4 bits (226), Expect = 7e-18
 Identities = 107/414 (25%), Positives = 172/414 (40%), Gaps = 78/414 (18%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAE----------- 48
           M +I+ +  R ++   G  +VEV+VA  +G F R A P   +   H A            
Sbjct: 1   MPIIEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGG 60

Query: 49  --ARRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARA 106
              ++AV  V + IGP +IG +A +Q L+D  L ++DGT D S +G N  L VS+A+A+A
Sbjct: 61  KGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKA 120

Query: 107 AANSKDMSLYSYIGGTFATELPVPIIQFASD----------ENF---------------- 140
           AA+S ++ L+ Y+GG  A  LPVP++   +           + F                
Sbjct: 121 AADSAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRW 180

Query: 141 --EYYILVRDLLE----VTDIVDAVNKIISEVGNKVSIEELSKASESVGMELGLEVALGI 194
             E Y  ++ +L+     T + D         G   +++ +S+A ES G+  G +VAL +
Sbjct: 181 GAEVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALAL 240

Query: 195 KMKRELEIEDVLNIVEDNNVA--------YIKPLGP-PELFLE------------LIAGT 233
                    D    V +            Y   LG  P + +E             +  +
Sbjct: 241 DAAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTAS 300

Query: 234 HG--VFIDGEYLF-----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPI 286
            G  V I G+ +F     R    ++R   NAL +K   +GTLT+  + V          +
Sbjct: 301 IGDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTM 360

Query: 287 LAEAKYEPADDTFPHLALGLRCPAMLIS----WNSVEKINELNRIAEELGERGR 336
           ++    E  D     LA+ +    +          V K N+L RI E LG+  R
Sbjct: 361 ISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAAR 414


>pir||T33721 phosphopyruvate hydratase (EC 4.2.1.11) eno - Zymomonas mobilis
           >gi|3089611|gb|AAC70360.1| (AF086791) enolase [Zymomonas
           mobilis]
           Length = 377
           
 Score = 92.4 bits (226), Expect = 7e-18
 Identities = 73/213 (34%), Positives = 112/213 (52%), Gaps = 22/213 (10%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51
           M+ I +I GR VV   G  +VEVDV  ++G FGR A P   +  +H A   R        
Sbjct: 1   MTAIVSIHGRQVVDSRGNPTVEVDVTLEDGSFGRAAVPSGASTGVHEAVELRDGDKTRWG 60

Query: 52  ------AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                 AV  V+  I   +IG +A +QELID  + ++DGT +    GAN  L VS+A+A+
Sbjct: 61  GKGVTKAVHAVNNEIANAIIGLEAEDQELIDQTMIKLDGTPNKGKFGANAILGVSLAVAK 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENFEYYILVRDLLEVTDIVDAVN 160
           AAA ++ + LY Y+GGT A  LPVP++        +D   ++   +   +  + I +AV 
Sbjct: 121 AAAEARGLPLYRYVGGTAAHVLPVPMMNIVNGGMHADNPIDFQEFMIAPVGASSINEAV- 179

Query: 161 KIISEVGNKVSIEELSKA-SESVGMELGLEVAL 192
           +I +EV + +  E  +K  + +VG E G   +L
Sbjct: 180 RIGTEVSHTLKKELSAKGMNTNVGDEGGFAPSL 212


>dbj|BAA81815.1| (AB029313) enolase [Streptococcus intermedius]
           Length = 434
           
 Score = 91.7 bits (224), Expect = 1e-17
 Identities = 101/419 (24%), Positives = 170/419 (40%), Gaps = 86/419 (20%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAE----------- 48
           MS+I ++  R V+   G  ++EV+V T+ G FGR   P   +   H A            
Sbjct: 1   MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYG 60

Query: 49  ---ARRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
               ++AV  V+ II   +IG+D  +Q+ ID  +  +DGT +   +GAN  L VSIA+AR
Sbjct: 61  GLGTQKAVDNVNNIIAEAVIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVAR 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFASDEN-------FEYYILV--------RDLL 150
           AAA+  ++ LYSY+GG     LP P++   +  +       F+ +++V          L 
Sbjct: 121 AAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIVPAGAPTFKEALR 180

Query: 151 EVTDIVDAVNKIISE-----------------VGNKVSIEELSKASESVGMELGLEVALG 193
              +I  A+ KI+                    G +  +E +  A E+ G   G +V LG
Sbjct: 181 WGAEIFHALKKILKSRGLATAVGDEGGFAPRFDGTEDGVETILAAIEAAGYVPGKDVFLG 240

Query: 194 IK------MKRELEIEDVLNI--------VEDNNVAYIKPLGPPELFLELIAGTHGVFID 239
                     +E ++ D              D  + Y++ L      + +  G      D
Sbjct: 241 FDCASSEFYDKERKVYDYTKFEGEGAAVRTADEQIDYLEELVNKYPIITIEDGMDENDWD 300

Query: 240 ----------------GEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDV 278
                           G+  F  N       ++    N++ IK   +GTLT+ ++ +   
Sbjct: 301 GWKKLTERLGKKVQPVGDDFFVTNTSYLEKGINEACANSILIKVNQIGTLTETFDAIEMA 360

Query: 279 KSEKITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333
           K    T +++    E  D T   +A+           L   + + K N+L RI ++LGE
Sbjct: 361 KEAGYTAVVSHRSGETEDSTIADIAVAANAGQIKTGSLSRTDRIAKYNQLLRIEDQLGE 419


>emb|CAC09537.1| (AL442120) enolase [Streptomyces coelicolor]
           Length = 426
           
 Score = 91.7 bits (224), Expect = 1e-17
 Identities = 101/414 (24%), Positives = 172/414 (41%), Gaps = 84/414 (20%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASPI-------------EENPMLHI 46
           M  I  ++ R ++   G  +VEV+V  D+G  GR A P              + +P  ++
Sbjct: 1   MPSIDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGASTGAFEAIELRDGDPSRYL 60

Query: 47  AEA-RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
            +   +AV  V E IGPEL+G+DA EQ LID  ++++D T++   +GAN  L VS+A+A 
Sbjct: 61  GKGVEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDNKGSLGANAILGVSLAVAH 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYI-------LVRDLL 150
           AA+ + D+ L+ Y+GG  A  LPVP++        +D N    E+ I           L 
Sbjct: 121 AASEASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVDIQEFMIAPIGAESFSEALR 180

Query: 151 EVTDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193
              ++   + K++   G                 N+ +++ + +A +  G   G ++AL 
Sbjct: 181 WGAEVYHTLKKVLKNKGLATGLGDEGGFAPNLGSNREALDLILEAIKEAGYTPGEQIALA 240

Query: 194 IKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHGVFID-------------- 239
           + +      +D     E  N +  +     E + EL+     V I+              
Sbjct: 241 LDVAASEFYKDGSYAFEGKNRSAAE---MTEYYAELVEAYPLVSIEDPLFEDDWDGWNTI 297

Query: 240 -----------GEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKI 283
                      G+ LF  N       ++    NAL +K   +G+LT+  + V   +    
Sbjct: 298 TAKLGDKVQLVGDDLFVTNPERLARGIEENSANALLVKVNQIGSLTETLDAVELAQRNGF 357

Query: 284 TPILAEAKYEPADDTFPHLALGLRCPAMLIS----WNSVEKINELNRIAEELGE 333
             +++    E  D T   LA+   C  +          V K N+L RI E L +
Sbjct: 358 KCMMSHRSGETEDVTIADLAVATNCGQIKTGAPARSERVAKYNQLLRIEEILDD 411


>sp|O66778|ENO_AQUAE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436875|pir||F70343 enolase - Aquifex
           aeolicus >gi|2983135|gb|AAC06738.1| (AE000692) enolase
           [Aquifex aeolicus]
           Length = 426
           
 Score = 91.7 bits (224), Expect = 1e-17
 Identities = 107/410 (26%), Positives = 174/410 (42%), Gaps = 78/410 (19%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPI-------------EENPMLHI 46
           MS I+ + GR V+   G  +VEV+V  + G  GR   P              + +P  ++
Sbjct: 1   MSRIKRVHGREVLDSRGNPTVEVEVELESGALGRAIVPSGASTGEREALELRDGDPKRYL 60

Query: 47  AEA-RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
            +   +AV  V+ +I   L+G +   Q  ID  L E+DGTE+ S +GAN  L  S+A+AR
Sbjct: 61  GKGVLKAVDNVNGVIAKALVGLEPYNQREIDQILIELDGTENKSKLGANAILGTSMAVAR 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFA-----SDENF---EYYIL------VRDLLE 151
           AAAN   + LY Y+GG F   LPVP++        +D N    E+ I+       R+ L 
Sbjct: 121 AAANELGIPLYEYLGGKFGYRLPVPLMNVINGGAHADNNLDIQEFMIVPVCGGAFREALR 180

Query: 152 V-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLEVALG 193
              +    + KI+ E G                 ++ +++ L +A E  G + G ++ L 
Sbjct: 181 AGVETFHHLKKILKEKGYSTNVGDEGGFAPNLNSSEEALDILMQAIEKAGYKPGEDILLA 240

Query: 194 IKMK--------------RELEIEDVLNIVEDNNVAY-IKPLGPP------ELFLELIAG 232
           + +               +E   E+++   E     Y I  +  P      E + E+   
Sbjct: 241 LDVASSEFYENGVYKFEGKERSAEEMIEFYEKLIQKYPIISIEDPMSENDWEGWKEITKR 300

Query: 233 T-HGVFIDGEYLFRANNILDRR-----YYNALSIKPINLGTLTDLYNFVNDVKSEKITPI 286
               V + G+ LF  N  + R+       NA+ +K   +GT+++  + V   K    + I
Sbjct: 301 LGDKVQLVGDDLFTTNPKILRKGIEEGVANAILVKLNQIGTVSETLDTVMLAKERNYSAI 360

Query: 287 LAEAKYEPADDTFPHLALGLRCPAMLISWNS----VEKINELNRIAEELG 332
           ++    E  D    HLA+      +     S    + K NEL RI E LG
Sbjct: 361 ISHRSGETEDTFISHLAVATNAGQIKTGSASRTDRIAKYNELLRIEERLG 410


>sp|Q60173|ENO_METJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|2118303|pir||A64329 phosphopyruvate
           hydratase (EC 4.2.1.11) - Methanococcus jannaschii
           >gi|1590967|gb|AAB98220.1| (U67479) enolase (eno)
           [Methanococcus jannaschii]
           Length = 427
           
 Score = 90.1 bits (220), Expect = 3e-17
 Identities = 86/281 (30%), Positives = 139/281 (48%), Gaps = 38/281 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATD-EGFGRFASPIEENPMLHIAEARR----------- 51
           I++I+ R V+   G  +VEV+V T   G+G    P   +   H A   R           
Sbjct: 11  IKDIVAREVIDSRGNPTVEVEVITKGNGYGSAIVPSGASTGTHEALELRDKEKRFGGKGV 70

Query: 52  --AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109
             AV  V+ II PE++G+DA  Q  ID+ + E+DGT + S +GAN  LAVS+A+A+AAA 
Sbjct: 71  LMAVENVNSIIRPEILGYDARMQREIDTIMIELDGTPNKSRLGANAILAVSLAVAKAAAA 130

Query: 110 SKDMSLYSYIGGTFATELPVPIIQF-------ASDENFEYYILVRDLLEVTDIVDAV--N 160
           +  + LY Y+GG  +  +PVP++          +D + + ++++   +  T I +AV   
Sbjct: 131 TAKIPLYKYLGGFNSYVMPVPMMNVINGGKHAGNDLDLQEFMIMP--VGATSISEAVRMG 188

Query: 161 KIISEVGNKVSIEELSKASESVGMELGLEVALGIKMKRE---LEIEDVLNIVEDNNVAYI 217
             +  V   V +E+  K + +VG E G   A  +K  RE   L  E V     ++ V + 
Sbjct: 189 SEVYHVLKNVILEKYGKNAVNVGDEGGF--APPLKTSREALDLLTESVKKAGYEDEVVFA 246

Query: 218 KPLGPPELFLELIAGTHGVFIDGEYLFRANNILDRRYYNAL 258
                 E + +   G +  +++G+ L R   +LD  YY AL
Sbjct: 247 LDAAASEFYKD---GYY--YVEGKKLTR-EELLD--YYKAL 279


>sp|O69174|ENO_STAAU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) (LAMININ BINDING PROTEIN)
           >gi|11268974|pir||T47276 phosphopyruvate hydratase (EC
           4.2.1.11) [imported] - Staphylococcus aureus
           >gi|3152725|gb|AAC17130.1| (AF065394) enolase
           [Staphylococcus aureus]
           Length = 434
           
 Score = 89.7 bits (219), Expect = 4e-17
 Identities = 104/422 (24%), Positives = 171/422 (39%), Gaps = 86/422 (20%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR-------- 51
           M +I ++  R V+   G  +VEV+V T+ G FGR   P   +   H A   R        
Sbjct: 1   MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYL 60

Query: 52  ------AVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAI 103
                 AV  V+EII PE+I   F  ++Q  ID  +  +DGT +   +GAN  L VSIA+
Sbjct: 61  GKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAV 120

Query: 104 ARAAANSKDMSLYSYIGGTFATELPVPIIQFASDEN-------FEYYILV--------RD 148
           ARAAA+     LY Y+GG    +LPVP++   +  +       F+ ++++          
Sbjct: 121 ARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKES 180

Query: 149 LLEVTDIVDAVNKIISE-----------------VGNKVSIEELSKASESVGMELGLEVA 191
           L   T+I   +  I+S+                  G + ++E + +A E+ G + G EV 
Sbjct: 181 LRWGTEIFHNLKSILSQRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVF 240

Query: 192 LGIKMK------------RELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGT------ 233
           LG                 + E E          V Y++ L      + +  G       
Sbjct: 241 LGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWD 300

Query: 234 ----------HGVFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDV 278
                       V + G+ LF  N       ++    N++ IK   +GTLT+ ++ +   
Sbjct: 301 GWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMA 360

Query: 279 KSEKITPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGER 334
           +    T +++    E  D T   +A+           L   + + K N+L RI +EL E 
Sbjct: 361 QKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFET 420

Query: 335 GR 336
            +
Sbjct: 421 AK 422


>sp|P48285|ENO_HELPY ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436877|pir||S58684 phosphopyruvate
           hydratase (EC 4.2.1.11) - Helicobacter pylori (strains
           26695 and others) >gi|2313236|gb|AAD07219.1| (AE000536)
           enolase (eno) [Helicobacter pylori 26695]
           Length = 426
           
 Score = 89.7 bits (219), Expect = 4e-17
 Identities = 85/342 (24%), Positives = 147/342 (42%), Gaps = 63/342 (18%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           RA   V+ +I   LIG +A+ Q  +D  L  +DGT +++++GAN  L VS+A+ARA+A +
Sbjct: 66  RACENVNSVIKHHLIGLEAINQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKA 125

Query: 111 KDMSLYSYIGGTFATELPVPIIQFASD--------------------ENF--------EY 142
            ++ LY Y+GG  A  LPVP++   +                     E+F        E 
Sbjct: 126 LNLPLYRYLGGANALTLPVPMLNIINGGTHANNSIDFQEYMIMPLGFESFKEALRASAEV 185

Query: 143 YILVRDLL----EVTDIVDAVNKIISEVGNKVSIEELSKASESVGMELGLEVALGIKMKR 198
           Y  ++ LL    ++T + D      +   N   +E +S+A E  G +LG E+AL + +  
Sbjct: 186 YHTLKKLLDGKNQLTSVGDEGGFAPNFSNNVEPLEVISQAIEKAGYKLGEEIALALDVAS 245

Query: 199 ELEIEDVLN--------IVEDNN-VAYIKPLGPPELFLELIAGT---------------- 233
              +++  N        I++ +  VAY K L      + +  G                 
Sbjct: 246 SELVDENFNYHLKGENKILDSHELVAYYKELVAKYPIVSIEDGLSEDDWEGWAFLSKELG 305

Query: 234 HGVFIDGEYLFRANNIL-----DRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILA 288
             + + G+ LF  N  L     ++   NA+ IKP  +GT+++    +   K      +++
Sbjct: 306 RQIQLVGDDLFVTNASLLQKGIEKNIANAVLIKPNQIGTISETLETIRLAKHHAYQCVMS 365

Query: 289 EAKYEPADDTFPHLALGLRCPAMLI-SWNSVEKINELNRIAE 329
               E  D      A+ L    +   S    E+I + NR+ E
Sbjct: 366 HRSGESEDSFIADFAVALNTGEIKTGSTARSERIAKYNRLLE 407


>sp|Q9ZMS6|ENO_HELPJ ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436886|pir||H71967 enolase -
           Helicobacter pylori (strain J99)
           >gi|4154655|gb|AAD05723.1| (AE001453) ENOLASE
           [Helicobacter pylori J99]
           Length = 426
           
 Score = 88.9 bits (217), Expect = 7e-17
 Identities = 81/342 (23%), Positives = 146/342 (42%), Gaps = 63/342 (18%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           RA   V+ +I   LIG +A  Q  +D  L  +DGT +++++GAN  L VS+A+ARA+A +
Sbjct: 66  RACENVNSVIKHHLIGLEATNQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKA 125

Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV--------RDLLEVTDI 155
            ++ LY Y+GG  A  LPVP++          +  +F+ Y+++          L    ++
Sbjct: 126 LNLPLYRYLGGANALTLPVPMLNIINGGTHANNSIDFQEYMIMPLGFESFKEALRASAEV 185

Query: 156 VDAVNKIISEVGNKVSI-----------------EELSKASESVGMELGLEVALGIKMKR 198
              + K++ E     S+                 E +S+A E  G +LG E+AL + +  
Sbjct: 186 YHTLKKLLDEKNQLTSVGDEGGFAPNFNNNVEPLEIISQAIEKAGYKLGEEIALALDVAS 245

Query: 199 ELEIEDVLN--------IVEDNN-VAYIKPLGPPELFLELIAGT---------------- 233
              +++  N        I++ +  VAY K L      + +  G                 
Sbjct: 246 SELVDEHFNYHLKGENKILDSHELVAYYKELVAKYPIVSIEDGLSEDDWEGWAFLSKELG 305

Query: 234 HGVFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILA 288
             + + G+ LF  N       +++   NA+ IKP  +GT+++    +   K      +++
Sbjct: 306 RQIQLVGDDLFVTNASILQKGIEKNVANAILIKPNQIGTISETLETIRLAKHHAYQCVIS 365

Query: 289 EAKYEPADDTFPHLALGLRCPAMLI-SWNSVEKINELNRIAE 329
               E  D      A+ L    +   S    E+I + NR+ E
Sbjct: 366 HRSGESEDSFIADFAVALNTGEIKTGSTARSERIAKYNRLLE 407


>sp|O30885|ENO_CAMFE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|2642185|gb|AAB86924.1| (AF020677)
           enolase [Campylobacter fetus]
           Length = 207
           
 Score = 86.2 bits (210), Expect = 5e-16
 Identities = 45/137 (32%), Positives = 79/137 (56%), Gaps = 15/137 (10%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           +A+  V+ +I  E+ G DA  Q+ ID  +  +DGT+++S IGAN  L VS+A+ARAAANS
Sbjct: 65  KAIKNVNSMIAEEICGKDAYNQKAIDDAMLALDGTDNYSRIGANAVLGVSMAVARAAANS 124

Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-------SDENFEYYILV--------RDLLEVTDI 155
            ++ LY Y+GG  A  LPVP+           +  +F+ ++++          L   T++
Sbjct: 125 LNIPLYRYLGGANACTLPVPMFNIINGGAHANNSVDFQEFMIMPFGFSKFSNALRAATEV 184

Query: 156 VDAVNKIISEVGNKVSI 172
              + KI++++G+  ++
Sbjct: 185 YQTLKKILNDLGHSTAV 201


>emb|CAC12011.1| (AL445065) enolase related protein [Thermoplasma acidophilum]
           Length = 401
           
 Score = 85.0 bits (207), Expect = 1e-15
 Identities = 97/395 (24%), Positives = 176/395 (44%), Gaps = 71/395 (17%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIE----ENPMLHIAEAR--RAVSEVD 57
           I+ I  R V+   G ++VE DV    GFGR ++P      E  ++  +++    ++   +
Sbjct: 5   IEEIKVRKVLDSRGNFTVEADVTVPNGFGRTSAPAGASTGETEVIAFSKSGIDASIQFFE 64

Query: 58  EIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYS 117
             +   LIGF+A++Q   D  L +IDG+ +FS++G N A A+S+++A+AAA S  + LY 
Sbjct: 65  SKVKRSLIGFNALDQSGFDKLLTDIDGSGNFSNLGGNLATALSMSVAKAAAQSLGIPLYR 124

Query: 118 YIGGTFATELPVPI-------------------IQFASDENF--EYYILVRDLLEVTDIV 156
           Y+GG  +T +P P+                   +  A    F    YI V     + D++
Sbjct: 125 YVGGIRST-IPRPMGNVIGGGKHARNGTSIQEFLVSAQGSTFLESAYINVLVHRRIGDML 183

Query: 157 DAVNKIIS-----------EVGNKVSIEELSKASESVGMELGLEVALGIKM--------- 196
               K IS            + ++ + E L++A + +  E  +++  G+           
Sbjct: 184 SDKFKDISIGVGDERTWSVNLSDEEAFEILNEAVKEISSEKKVKIYTGVDFAADSLYENG 243

Query: 197 ---------KRELEIEDVLNIVEDNNVAYIK-PLGPPEL--FLELIA--GTHGVFIDGEY 242
                     R+ +I+  ++I +D  V YI+ P+   +   F E+ A  G   + + G+ 
Sbjct: 244 KYVYKHTTKSRDEQIDYAISISKDFGVYYIEDPMYDTDFDGFAEITARIGDRSLIV-GDD 302

Query: 243 LFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAKYEPADD 297
           L+  N       ++++  NA+ IK   +GTL+     V       +  I++    E  DD
Sbjct: 303 LYTTNPDRIRKGVEKKSTNAVLIKVNQIGTLSAAREAVAVATFAGMKNIVSHRSGETTDD 362

Query: 298 TFPHLALGLRCPAM---LISWNSVEKINELNRIAE 329
              HL++      +   +I    V K+NE+ RI E
Sbjct: 363 FLAHLSVAFGSTFVKTGVIGGERVAKLNEIARIEE 397


>dbj|BAB07786.1| (AB046715) enolase [Desulfovibrio vulgaris]
           Length = 434
           
 Score = 84.7 bits (206), Expect = 1e-15
 Identities = 100/415 (24%), Positives = 171/415 (41%), Gaps = 80/415 (19%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASP----IEENPMLHIAEA------ 49
           MS I ++  R ++   G  +VEV+V+ + G  GR A P          L + +       
Sbjct: 1   MSTIVSVWAREILDSRGNPTVEVEVSLESGHTGRAAVPSGASTGSREALEMRDGDKGRYK 60

Query: 50  ----RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                +AV  V   I   ++G D++ Q  +D+ L ++DGT++ S +GAN  L VS+A AR
Sbjct: 61  GKGVEKAVDNVMGEIAEAIVGLDSLRQVQVDNTLLDLDGTDNKSRLGANAMLGVSLATAR 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPIIQFASD--------ENFEYYIL------VRDLLE 151
           AA++   + LY Y+GG  A  LPVP++   +         +  E+ I+       RD L 
Sbjct: 121 AASSFLGLPLYQYLGGVNAKVLPVPLMNIINGGAHAPNNLDIQEFMIMPIGAATFRDALR 180

Query: 152 V-TDIVDAVNKIISEVGNKVSIEE-----------------LSKASESVGMELGLEVALG 193
           +  +    +  +++  G+  S+ +                 + KA E  G   G E+AL 
Sbjct: 181 MGAETFHTLKALLAADGHVTSVGDEGGFAPNLKNHDEAFRYIMKAIEEAGYIPGAEIALA 240

Query: 194 IKMKRELEIEDVLNIVED-----NNVAYIKPLGPPELFLELIAGTHG------------- 235
           I        +D   ++       +N   ++ LG       LI+   G             
Sbjct: 241 IDAAASEFHKDGKYVLAGEGKNLSNSEMVEWLGEFTTRYPLISIEDGLAEADWDGWRELT 300

Query: 236 ------VFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKIT 284
                 + + G+ +F  N       +D    N++ IK   +GTLT+  + +   K    T
Sbjct: 301 YKLGDTIQLVGDDIFVTNPDILAEGIDEGVANSILIKLNQIGTLTETLDTIEMAKQAAYT 360

Query: 285 PILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGERG 335
            +++    E  D     LA+GL         L   + + K N+L RI E+L + G
Sbjct: 361 TVISHRSGETEDHFISDLAVGLNAGQIKTGSLCRSDRLAKYNQLLRIEEDLDDTG 415


>gb|AAF13454.1|AF205070_1 (AF205070) enolase [Mastigamoeba balamuthi]
           Length = 439
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 102/424 (24%), Positives = 179/424 (42%), Gaps = 92/424 (21%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR--------- 50
           MS I+++  R ++   G  +VEVD+ T++G  R A P   +  ++ A E R         
Sbjct: 1   MSTIKSVFAREILDSRGNPTVEVDLTTEKGLFRSAVPSGASTGIYEACELRDGDKSRYLG 60

Query: 51  ----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARA 106
               +AV  V++I+ P+LIG D  +Q  ID  + +IDGTE+ +H+GAN  L  S+++ RA
Sbjct: 61  KGVLKAVENVNKILAPKLIGLDVTKQGEIDRLMLQIDGTENKTHLGANAILGCSMSVCRA 120

Query: 107 AANSKDMSLYSYI---GGTFATELPVP--------------------------------I 131
           AA  + + LY YI    G  +  LP+P                                 
Sbjct: 121 AAAFRGLPLYRYIAELSGNKSPMLPLPCFNVINGGEHAGNKLAMQEFMICPTGATSFHEA 180

Query: 132 IQFASD--ENFEYYILVRDLLEVTDIVD----AVNKIISEVGNKVSIEELSKASESVGME 185
           ++ A++   N +  I  R  ++ T++ D    A N   +  G ++ +E + +A  +  +E
Sbjct: 181 LRMAAETYHNLKLVIKKRYGMDATNVGDEGGFAPNIQANHEGLELIVEAIKQAGYTGKIE 240

Query: 186 LGLEVA-------------LGIKMKRELEIEDVL-------NIVEDNNVAY-IKPLGPP- 223
           +G++VA             LG K+  + +  D+L        + E+    Y I  +  P 
Sbjct: 241 IGMDVAASSFWDAKESKYDLGFKVPADKKTPDMLVSGEGLIKLYEEWTSKYPIWSIEDPF 300

Query: 224 --------ELFLELIAGTHGVFIDGEYLFRANNILD---RRYYNALSIKPINLGTLTDLY 272
                     F ELI     +  D   +     I++   ++  NAL +K   +G++++  
Sbjct: 301 DQDDWATYTRFTELIRNRIQIVGDDLLVTNPKRIVEARNKKACNALLLKLNQIGSVSEAV 360

Query: 273 NFVNDVKSEKITPILAEAKYEPADDTFPHLALGLRCPAMLIS----WNSVEKINELNRIA 328
                 +      +++    E  D     L +GL C  +          + K N+L RI 
Sbjct: 361 EACRLAREVNWGVMVSHRSGETEDAFIADLVVGLGCGQIKTGAPCRSERLAKYNQLLRIE 420

Query: 329 EELG 332
           EELG
Sbjct: 421 EELG 424


>sp|Q57651|Y198_METJA HYPOTHETICAL PROTEIN MJ0198 >gi|2128174|pir||G64324 hypothetical
           protein MJ0198 - Methanococcus jannaschii
           >gi|1592276|gb|AAB98193.1| (U67476) M. jannaschii
           predicted coding region MJ0198 [Methanococcus
           jannaschii]
           Length = 314
           
 Score = 83.9 bits (204), Expect = 2e-15
 Identities = 74/327 (22%), Positives = 145/327 (43%), Gaps = 63/327 (19%)

Query: 2   SVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARRAVSEVDEIIG 61
           +VI   I    V +G    V +   T+   G          ++ +     A+++V+ +I 
Sbjct: 3   NVIIEKISAKEVFKGAKIKVMITTMTNISIGY--------DIIEVNNPEEAIADVENVIA 54

Query: 62  PELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYIGG 121
           PELIG+ A + + IDS + E       S      A+ +SI++ARAA+NS D+ L+ ++GG
Sbjct: 55  PELIGYPATDIDFIDSLICET------SVNNPTVAMGISISVARAASNSLDIPLFKFLGG 108

Query: 122 TFATELPVPI--IQFASDENFEYYILVRDLLEVTDIVDAVNKIISEVGNKVSIEELSKA- 178
              TELP+    I    D+N    I++ D +E  DIV+   K+   + +  SI  +  A 
Sbjct: 109 ALTTELPIVASGILVDKDKNELIPIVMADSIE--DIVNLYLKLTDVLSHDYSIVNIDGAY 166

Query: 179 ---------------SESVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAYIKPLGPP 223
                           + +  +  L++ LG+  K+E         V+D +++ I  L   
Sbjct: 167 TCKDIFNEIPKIRNLIDEIKEDEDLDILLGLSSKKE--------TVKDKDLSQIDYLEVE 218

Query: 224 E-LFLELIAGTHGVFIDGEYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEK 282
           E +  +    T  ++ + ++               + + P  +GT+T++Y ++N +  + 
Sbjct: 219 EPVEFDGFLCTDSIYEESDF---------------VKVFPYEMGTITEMYYYINYIMDKG 263

Query: 283 ITPILAEAKYEPADDTFPHLALGLRCP 309
           + P++        + +F H+A+  + P
Sbjct: 264 LYPVIF-----GNNSSFAHIAVSFKVP 285


>gb|AAC47644.1| (U85832) enolase [Stylochus zebra]
           Length = 168
           
 Score = 83.1 bits (202), Expect = 4e-15
 Identities = 56/145 (38%), Positives = 78/145 (53%), Gaps = 18/145 (12%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51
           I+ I GR +    G  +VEVD+ T++G  R A P   +  +H A   R            
Sbjct: 3   IKKIHGRQIFDSRGNPTVEVDITTEKGMFRAAVPSGASTGVHEALEMRDKAKEYMGKGVL 62

Query: 52  -AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAA 108
            AV+ V+ +IGP LI  GF  VEQE ID+++ E+DGTE+ + +GAN  L VS+A+ +A A
Sbjct: 63  NAVNNVNNVIGPALIAKGFSVVEQENIDNFMLELDGTENKAKLGANAILGVSLAVLKAGA 122

Query: 109 NSKDMSLYSYI---GGTFATELPVP 130
             K   LY +I    G     LPVP
Sbjct: 123 AQKGTPLYRHIADLAGNNEVILPVP 147


>gb|AAF73201.1|AF152348_1 (AF152348) enolase [Trypanosoma brucei brucei]
           Length = 429
           
 Score = 81.9 bits (199), Expect = 1e-14
 Identities = 55/144 (38%), Positives = 79/144 (54%), Gaps = 17/144 (11%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASP------IEENPMLHIAEARR------ 51
           IQ + GR V+   G  +VEV+V T+ G  R A P      + E   L   + +R      
Sbjct: 3   IQKVHGREVLDSRGNPTVEVEVTTERGVFRSAVPSGASTGVYEACELRDGDKKRYVGKGC 62

Query: 52  --AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109
             AV  V+E+IGP LIG D ++QE +D+ +  +DGT +   +GAN  L  S+AI++AAA 
Sbjct: 63  LQAVKNVNEVIGPALIGRDELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISKAAAA 122

Query: 110 SKDMSLYSY---IGGTFATELPVP 130
           +K + LY Y   + GT    LPVP
Sbjct: 123 AKGVPLYRYLASLAGTKELRLPVP 146


>sp|Q9Z7A6|ENO_CHLPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436889|pir||A72034 enolase -
           Chlamydophila pneumoniae (strain CWL029)
           >gi|4377111|gb|AAD18938.1| (AE001661) Enolase
           [Chlamydophila pneumoniae CWL029]
           Length = 428
           
 Score = 81.5 bits (198), Expect = 1e-14
 Identities = 92/345 (26%), Positives = 138/345 (39%), Gaps = 65/345 (18%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           +AV  V EI+ P + G    EQ LIDS + + DG+ +   +GAN  L VS+A A AAA +
Sbjct: 68  QAVKNVKEILFPLVKGCSVYEQSLIDSLMMDSDGSPNKETLGANAILGVSLATAHAAAAT 127

Query: 111 KDMSLYSYIGGTFATELPVPIIQFA-----SDENFEYYILVRDLLEVTDIVDAVN----- 160
               LY Y+GG FA  LP P++        +D   E+   +   +  + I +AVN     
Sbjct: 128 LRRPLYRYLGGCFACSLPCPMMNLINGGMHADNGLEFQEFMIRPIGASSIKEAVNMGADV 187

Query: 161 -----KIISEVG-----------------NKVSIEELSKASESVGMELGLEVALGIKMKR 198
                K++ E G                 N+ ++E L  A E  G   G +++L +    
Sbjct: 188 FHTLKKLLHERGLSTGVGDEGGFAPNLASNEEALELLLLAIEKAGFTPGKDISLALDCAA 247

Query: 199 ----------------ELEIEDVLNIVEDNNVAYIKPLGPPE------LFLELIAGTHGV 236
                           E +I  + N+ +   +  I+     E      L  E++     V
Sbjct: 248 SSFYNVKTGTYDGRHYEEQIAILSNLCDRYPIDSIEDGLAEEDYDGWALLTEVLG--EKV 305

Query: 237 FIDGEYLFRANNIL-----DRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEAK 291
            I G+ LF  N  L          N++ IKP  +GTLT+    +   +    T I++   
Sbjct: 306 QIVGDDLFVTNPELILEGISNGLANSVLIKPNQIGTLTETVYAIKLAQMAGYTTIISHRS 365

Query: 292 YEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELG 332
            E  D T   LA+           L     V K N L  I EELG
Sbjct: 366 GETTDTTIADLAVAFNAGQIKTGSLSRSERVAKYNRLMEIEEELG 410


>sp|P42448|ENO_CAMJE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|11268976|pir||E81264 phosphopyruvate
           hydratase (EC 4.2.1.11) Cj1672c [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6969088|emb|CAB73659.1| (AL139079) enolase
           [Campylobacter jejuni]
           Length = 414
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 40/81 (49%), Positives = 56/81 (68%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           +AV+ V+E I  E++G DA  Q  +D  L E+DGT ++S++GAN  L VS+A ARAAA +
Sbjct: 65  KAVANVNETIADEILGLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATARAAAAA 124

Query: 111 KDMSLYSYIGGTFATELPVPI 131
             M LY Y+GG  A+ LPVP+
Sbjct: 125 LGMPLYRYLGGANASILPVPM 145


>sp|P08324|ENO_ECOLI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7428364|pir||NOEC phosphopyruvate
           hydratase (EC 4.2.1.11) - Escherichia coli  (strain
           K-12) >gi|882673|gb|AAA69289.1| (U29580) enolase
           [Escherichia coli] >gi|1789141|gb|AAC75821.1| (AE000361)
           enolase [Escherichia coli K12]
           Length = 432
           
 Score = 80.0 bits (194), Expect = 4e-14
 Identities = 107/427 (25%), Positives = 182/427 (42%), Gaps = 101/427 (23%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASP----IEENPMLHIAEA------ 49
           MS I  IIGR ++   G  +VE +V  + GF G  A+P          L + +       
Sbjct: 1   MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFL 60

Query: 50  ----RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                +AV+ V+  I   LIG DA +Q  ID  + ++DGTE+ S  GAN  LAVS+A A+
Sbjct: 61  GKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAK 120

Query: 106 AAANSKDMSLYSYIGGTFAT----ELPVPIIQFA-----SDENF---EYYI------LVR 147
           AAA +K M LY +I     T     +PVP++        +D N    E+ I       V+
Sbjct: 121 AAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVK 180

Query: 148 DLLEV-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLE 189
           + + + +++   + K++   G                 N  ++  +++A ++ G ELG +
Sbjct: 181 EAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKD 240

Query: 190 VALGI------------------------------------KMKRELEIEDVLNIVEDNN 213
           + L +                                    K    + IED L+  + + 
Sbjct: 241 ITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDG 300

Query: 214 VAY-IKPLGPPELFLELIAGTHGVFIDGEYLFRANNILDRRYYNALSIKPINLGTLTDLY 272
            AY  K LG     ++L+     +F+    + +    +++   N++ IK   +G+LT+  
Sbjct: 301 FAYQTKVLGDK---IQLVG--DDLFVTNTKILKEG--IEKGIANSILIKFNQIGSLTETL 353

Query: 273 NFVNDVKSEKITPILAEAKYEPADDTFPHLALG-----LRCPAMLISWNSVEKINELNRI 327
             +   K    T +++    E  D T   LA+G     ++  +M  S + V K N+L RI
Sbjct: 354 AAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRS-DRVAKYNQLIRI 412

Query: 328 AEELGER 334
            E LGE+
Sbjct: 413 EEALGEK 419


>pir||E82076 enolase VC2447 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9657023|gb|AAF95589.1| (AE004314) enolase
           [Vibrio cholerae]
           Length = 433
           
 Score = 80.0 bits (194), Expect = 4e-14
 Identities = 103/421 (24%), Positives = 176/421 (41%), Gaps = 88/421 (20%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASPIEENPMLHIA-EAR-------- 50
           MS I  ++GR ++   G  +VE +V  + GF G  A+P   +     A E R        
Sbjct: 1   MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFL 60

Query: 51  -----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                +A++ V+  I   L+G DA +Q  ID  + ++DGTE+ S+ GAN  LAVS+A A+
Sbjct: 61  GKGVLKALAAVNGPIADALVGKDAKDQATIDQIMIDLDGTENKSNFGANAILAVSLANAK 120

Query: 106 AAANSKDMSLYSYIGGTFAT----ELPVPIIQFA-----SDENFEYYILVRDLLEVTDIV 156
           AAA +K M LY +I     T     +P+P++        +D N +    +   +    + 
Sbjct: 121 AAAAAKGMPLYEHIAELNGTPGVFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLK 180

Query: 157 DAVN----------KIISEVG-----------------NKVSIEELSKASESVGMELGLE 189
           +AV           K++   G                 N  ++E +++A  + G +LG +
Sbjct: 181 EAVRMGAEVFHNLAKVLKSKGYNTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYKLGTD 240

Query: 190 VALGIKM---------KRELEIEDVLNIVEDNNVA-YIKPLGPPELFLELIAGT------ 233
           + L +           K+E  ++    I   N  + +++ L      + +  G       
Sbjct: 241 ITLAMDCAASEFYDAEKKEYNLKGEGRIFTSNGFSDFLEELTEKFPIVSIEDGLDESDWE 300

Query: 234 ----------HGVFIDGEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVNDV 278
                       + I G+ LF  N       +D    N++ IK   +G+LT+    +   
Sbjct: 301 GFAYQTEKLGKKIQIVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMA 360

Query: 279 KSEKITPILAEAKYEPADDTFPHLALG-----LRCPAMLISWNSVEKINELNRIAEELGE 333
           K    T +++    E  D T   LA+G     ++  +M  S + V K N+L RI E LG 
Sbjct: 361 KDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRS-DRVAKYNQLIRIEEALGS 419

Query: 334 R 334
           R
Sbjct: 420 R 420


>emb|CAA57795.1| (X82400) enolase [Escherichia coli]
           Length = 437
           
 Score = 80.0 bits (194), Expect = 4e-14
 Identities = 108/429 (25%), Positives = 181/429 (42%), Gaps = 101/429 (23%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASP----IEENPMLHIAEA------ 49
           MS I  IIGR ++   G  +VE +V  + GF G  A+P          L + +       
Sbjct: 1   MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFL 60

Query: 50  ----RRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                +AV+ V+  I   LIG DA +Q  ID  + ++DGTE  S  GAN  LAVS+A A+
Sbjct: 61  GKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEKKSKFGANAILAVSLANAK 120

Query: 106 AAANSKDMSLYSYIGGTFAT----ELPVPIIQFA-----SDENF---EYYI------LVR 147
           AAA +K M LY +I     T     +PVP++        +D N    E+ I       V+
Sbjct: 121 AAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVK 180

Query: 148 DLLEV-TDIVDAVNKIISEVG-----------------NKVSIEELSKASESVGMELGLE 189
           + + + +++   + K++   G                 N  ++  +++A ++ G ELG +
Sbjct: 181 EAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNDEALAVIAEAVKAAGYELGKD 240

Query: 190 VALGI------------------------------------KMKRELEIEDVLNIVEDNN 213
           + L +                                    K    + IED L+  + + 
Sbjct: 241 ITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDG 300

Query: 214 VAY-IKPLGPPELFLELIAGTHGVFIDGEYLFRANNILDRRYYNALSIKPINLGTLTDLY 272
            AY  K LG     ++L+     +F+    + +    +++   N+  IK   +G+LT+  
Sbjct: 301 FAYQTKVLGDK---IQLVG--DDLFVTNTKILKEG--IEKGIANSYLIKFNQIGSLTETL 353

Query: 273 NFVNDVKSEKITPILAEAKYEPADDTFPHLALG-----LRCPAMLISWNSVEKINELNRI 327
             +   K    T +++    E  D T   LA+G     ++  +M  S + V K N+L RI
Sbjct: 354 AAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRS-DRVAKYNQLIRI 412

Query: 328 AEELGERGR 336
            E LGE+ R
Sbjct: 413 EEALGEKAR 421


>emb|CAB94910.1| (AJ401152) enolase [Enterococcus faecalis]
           Length = 432
           
 Score = 79.6 bits (193), Expect = 5e-14
 Identities = 54/147 (36%), Positives = 81/147 (54%), Gaps = 15/147 (10%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIA-------EAR-- 50
           MS+I +I  R V+   G  ++EV+V T+ G FGR   P   +   + A       +AR  
Sbjct: 1   MSIITDIYAREVLDSRGNPTIEVEVYTESGAFGRGMVPSGASTGEYEAVELRDGDKARYL 60

Query: 51  -----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                +AV  V+ II   +IG+D  +Q  ID  + ++DGT +   +GAN  L VSIA+AR
Sbjct: 61  GKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIDLDGTPNKGKLGANAILGVSIAVAR 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPII 132
           AAA+  ++ LY Y+GG     LP P++
Sbjct: 121 AAADYLEVPLYHYLGGFNTKVLPTPMM 147


>gb|AAC47645.1| (U85834) enolase [Tubularia sp.]
           Length = 166
           
 Score = 77.6 bits (188), Expect = 2e-13
 Identities = 53/149 (35%), Positives = 80/149 (53%), Gaps = 19/149 (12%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPI-------------EENPMLHIA 47
           MS +  I  R ++   G  +VEVD+AT  G  R A P              +++P  ++ 
Sbjct: 1   MSGVTKIHAREILDSRGNPTVEVDLATSRGVFRAAVPSGASTGIYEALELRDKDPKRYLG 60

Query: 48  E-ARRAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIA 104
           + A +AVS +++IIGP LI    D  +Q  +D  + E+DGTE+ S +GAN  LAVS+A+ 
Sbjct: 61  KGALKAVSNINDIIGPALISKNIDCTQQGEVDKIMLELDGTENKSKLGANAILAVSLAVC 120

Query: 105 RAAANSKDMSLYSYI---GGTFATELPVP 130
           +A A  K + LY +I    G     +PVP
Sbjct: 121 KAGAAHKGVPLYKHIADLAGNSKVIMPVP 149


>sp|O84591|ENO_CHLTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436872|pir||D71496 probable enolase -
           Chlamydia trachomatis (serotype D, strain UW3/Cx)
           >gi|3329030|gb|AAC68189.1| (AE001329) Enolase [Chlamydia
           trachomatis]
           Length = 424
           
 Score = 76.9 bits (186), Expect = 3e-13
 Identities = 98/406 (24%), Positives = 167/406 (40%), Gaps = 76/406 (18%)

Query: 3   VIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP------IEENPMLHIAEARR---- 51
           VI +I  R ++   G  ++ V V T+ G FG    P      I+E   L   + +R    
Sbjct: 5   VISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQGK 64

Query: 52  ----AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
               A+S V++++ P L GF   +Q   D+ + + DGT +   +GAN  L VS+A+A+AA
Sbjct: 65  GVLQAISNVEKVLMPALQGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALAKAA 124

Query: 108 ANSKDMSLYSYIGGTFATELPVPIIQF-------ASDENFEYYIL----VRDLLEV---- 152
           AN+    LY Y+GG+F+  LP P++          +   F+ +++       L E     
Sbjct: 125 ANTLQRPLYRYLGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLTEAVRMG 184

Query: 153 TDIVDAVNKIISE-----------------VGNKVSIEELSKASESVGMELGLEVALGIK 195
            ++ +A+ KI+                     N  +++ L  A E+ G     +++L + 
Sbjct: 185 AEVFNALKKILQNRQLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPREDISLALD 244

Query: 196 MKREL----------------EIEDVLNIVEDNNVAYIKPLGPPELF--LELIAGTHG-- 235
                                ++  +  + E   +  I+     E F   +L++ T G  
Sbjct: 245 CAASSFYNTQDKTYDGKSYADQVGILAELCEHYPIDSIEDGLAEEDFEGWKLLSETLGDR 304

Query: 236 VFIDGEYLFRANNIL-----DRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPILAEA 290
           V + G+ LF  N+ L      +   NA+ IKP  +GTLT+    +     +    IL+  
Sbjct: 305 VQLVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATIQGYATILSHR 364

Query: 291 KYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELG 332
             E  D T   LA+           L     + K N L  I EE+G
Sbjct: 365 SGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEEEMG 410


>pir||A72477 probable enolase APE2458 - Aeropyrum pernix (strain K1)
           >gi|5106162|dbj|BAA81473.1| (AP000064) 432aa long
           hypothetical enolase [Aeropyrum pernix]
           Length = 432
           
 Score = 76.5 bits (185), Expect = 4e-13
 Identities = 83/345 (24%), Positives = 146/345 (42%), Gaps = 70/345 (20%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           RAVS ++ ++ P L G DA  Q  ID  L E+DGT + S +G NT  A+SIA++RAAA  
Sbjct: 69  RAVSLLNTVVAPRLEGVDARRQAQIDRLLIELDGTPNKSRLGGNTTTALSIAVSRAAAAQ 128

Query: 111 KDMSLYSYIGGTFATELPVPI-------IQFASDENFEYYILV----------------- 146
             + L+ Y+GG  A  LP+P+       +   ++ +F+ ++++                 
Sbjct: 129 ARLELFQYLGGAGARRLPIPLLNVINGGVHAGNELDFQEFMIIPYGFESFTEAMRAAVET 188

Query: 147 ----RDLLEVTDIVDAVNKIISEVGN--------KVSIEELSKASESVGMELGLEVALGI 194
               + LL+      AVN  + + G         + +++ L  A E  G + G E+ALGI
Sbjct: 189 YGELKSLLKDRYGASAVN--VGDEGGFAPPMRSAEEALKTLVDAVEKAGYQPGSEIALGI 246

Query: 195 KMK--------------RELEIEDVLN----IVEDNNVAYIK-PLGPP--ELFLELI--A 231
                            + L  E++L+    +VE   + Y++ P      E F   +   
Sbjct: 247 DAAASQLYSNGRYSVEGKSLSREELLSLYQRLVEQYPIVYLEDPFSEDDYEGFKAAVDAL 306

Query: 232 GTHGVFIDGEYLF----RANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKITPIL 287
            T  + +  + L     R       +    L +K   +GTLT+    +   +   I  I+
Sbjct: 307 STETIIVGDDLLVTNPQRVKEASALKAVTGLLVKVNQVGTLTEALEAIQAARDRGIVHIV 366

Query: 288 AEAKYEPADDTFPHLALGLRCPAMLISWNSV---EKINELNRIAE 329
           +    +  D     LA+     A++I   +    E+ ++ NR+ E
Sbjct: 367 SHRSGDTEDTFIADLAVATE--ALMIKTGAPARGERTSKYNRLLE 409


>sp|Q27527|ENO_CAEEL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7508094|pir||T25040 hypothetical
           protein T21B10.2 - Caenorhabditis elegans
           >gi|3879986|emb|CAA92692.1| (Z68318) contains similarity
           to Pfam domain: PF00113 (Enol-ase), Score=1030.7,
           E-value=0, N=1~cDNA EST EMBL:Z14384 comes from this
           gene~cDNA EST EMBL:T02304 comes from this gene~cDNA EST
           yk99b2.5 comes from this gene~cDNA EST yk55g12.5 comes
           from this >
           Length = 434
           
 Score = 75.7 bits (183), Expect = 7e-13
 Identities = 55/146 (37%), Positives = 77/146 (52%), Gaps = 19/146 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           I  I  R +    G  +VEVD+ T++G  R A P   +  +H A E R            
Sbjct: 3   ITKIHARQIYDSRGNPTVEVDLFTEKGVFRAAVPSGASTGVHEALELRDGDKAVHLGKGV 62

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AVS ++E I P LI  GFD   Q+ ID ++  +DG+E+  ++GAN  L VS+A+A+A 
Sbjct: 63  LKAVSNINEKIAPALIAKGFDVTAQKDIDDFMMALDGSENKGNLGANAILGVSLAVAKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130
           A  K + LY YI    GT    LPVP
Sbjct: 123 AVHKGLPLYKYIAELAGTGKVVLPVP 148


>sp|P40370|ENO1_SCHPO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|1076907|pir||JC4036 phosphopyruvate
           hydratase (EC 4.2.1.11) - fission yeast
           (Schizosaccharomyces pombe) >gi|535442|gb|AAA70080.1|
           (U13799) enolase [Schizosaccharomyces pombe]
           Length = 439
           
 Score = 75.3 bits (182), Expect = 9e-13
 Identities = 51/147 (34%), Positives = 72/147 (48%), Gaps = 20/147 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51
           IQ +  R +   GG  +VEVD+ T+ G  R   P   +  +  A   R            
Sbjct: 3   IQKVFARQIYALGGNPTVEVDLTTETGIHRAIVPSGASTGIWEALEMRDGDKTKWGGKGV 62

Query: 52  --AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
             AV  V+ II P ++    D  +Q+  D +L ++DGTE+ S +GAN  L VS+AI RA 
Sbjct: 63  LKAVGNVNNIIAPAVVKANLDVTDQKAADEFLLKLDGTENKSKLGANAILGVSMAICRAG 122

Query: 108 ANSKDMSLYSYIGGTFATE----LPVP 130
           A  K + L+ YI   F T+    LPVP
Sbjct: 123 AAQKKLPLWKYIAENFGTKGPYVLPVP 149


>gb|AAC43380.1| (U13756) enolase [Helicobacter pylori]
           Length = 178
           
 Score = 75.3 bits (182), Expect = 9e-13
 Identities = 35/82 (42%), Positives = 54/82 (65%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           RA   V+ +I   LIG +A  Q  +D  L  +DGT +++++GAN  L VS+A+ARA+A +
Sbjct: 66  RACENVNSVIKHHLIGLEATNQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKA 125

Query: 111 KDMSLYSYIGGTFATELPVPII 132
            ++ LY Y+GG  A  LPVP++
Sbjct: 126 LNLPLYRYLGGANALTLPVPML 147


>emb|CAB96125.1| (AJ272111) enolase [Euglena gracilis]
           Length = 431
           
 Score = 75.3 bits (182), Expect = 9e-13
 Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 18/149 (12%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASP----IEENPMLHIAEARRAV-- 53
           M VI+ +  R ++   G  +VEVDV  D G  GR A P      E   + + +  +AV  
Sbjct: 1   MPVIKTVKARQILDSRGNPTVEVDVILDNGLLGRGAVPSGASTGEYEAVELRDGDKAVYL 60

Query: 54  --------SEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                     V+ I+ P+L+G D  EQ  ID+ + E+DGT +   IGAN  L VS+A+ R
Sbjct: 61  GKGVLKSVEAVNTIVAPKLVGLDPTEQLKIDNLMRELDGTPNKGKIGANGILGVSMAVCR 120

Query: 106 AAANSKDMSLYSYIG---GTFATELPVPI 131
           AAA  K + LY +IG   G    ++PVP+
Sbjct: 121 AAALVKGVPLYRHIGDLHGNKTFQMPVPM 149


>gb|AAC47639.1| (U85833) enolase [Hymenolepis diminuta]
           Length = 168
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 55/149 (36%), Positives = 77/149 (50%), Gaps = 20/149 (13%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR--------- 51
           MS+++ I  R +    G  +VEVD+ TD G  R A P   +  +H A   R         
Sbjct: 1   MSIVK-IHARQIFDSRGNPTVEVDLFTDNGMFRAAVPSGASTGVHEAVELRDNDKANYMG 59

Query: 52  -----AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIA 104
                AV  V++II PELI  GF   EQE ID ++ ++DGT++   +GAN  L VS+A+ 
Sbjct: 60  KGVLNAVKNVNDIIAPELIKKGFKVTEQEAIDEFMIKLDGTKNKGKLGANAILGVSLAVC 119

Query: 105 RAAANSKDMSLYSYI---GGTFATELPVP 130
           +A A  K + LY +I    G     LPVP
Sbjct: 120 KAGAALKGVPLYRHIAELAGNKDVILPVP 148


>sp|P15007|ENO_DROME ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|84950|pir||S07586 phosphopyruvate
           hydratase (EC 4.2.1.11) - fruit fly  (Drosophila
           melanogaster) >gi|7946|emb|CAA34895.1| (X17034) enolase
           (AA 1-433) [Drosophila melanogaster]
           Length = 433
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 74/266 (27%), Positives = 121/266 (44%), Gaps = 38/266 (14%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA--------------EA 49
           I+ I  R +    G  +VEVD+ T+ G  R A P   +  +H A                
Sbjct: 3   IKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSV 62

Query: 50  RRAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  V++ +GPELI    D V+Q  ID+++ ++DGTE+ S  GAN  L VS+A+A+A 
Sbjct: 63  LKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVPIIQFASDENF--------EYYILVRDLLEVTDIV 156
           A  K + LY +I    G     LPVP     +  +         E+ IL       T+ +
Sbjct: 123 AAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182

Query: 157 DAVNKIISEVGNKVSIEELSKASESVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAY 216
              +++   + N +   +    + +VG E G   A  I+  +E      LN++ D  +A 
Sbjct: 183 KMGSEVYHHLKNVIK-AKFGLDATAVGDEGGF--APNIQSNKE-----ALNLISD-AIAK 233

Query: 217 IKPLGPPELFLELIAGTHGVFIDGEY 242
               G  E+ +++ A     + DG+Y
Sbjct: 234 AGYTGKIEIGMDVAASE--FYKDGQY 257


>gb|AAF51344.1| (AE003585) Eno gene product [Drosophila melanogaster]
           Length = 433
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 74/266 (27%), Positives = 121/266 (44%), Gaps = 38/266 (14%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA--------------EA 49
           I+ I  R +    G  +VEVD+ T+ G  R A P   +  +H A                
Sbjct: 3   IKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSV 62

Query: 50  RRAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  V++ +GPELI    D V+Q  ID+++ ++DGTE+ S  GAN  L VS+A+A+A 
Sbjct: 63  LKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVPIIQFASDENF--------EYYILVRDLLEVTDIV 156
           A  K + LY +I    G     LPVP     +  +         E+ IL       T+ +
Sbjct: 123 AAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182

Query: 157 DAVNKIISEVGNKVSIEELSKASESVGMELGLEVALGIKMKRELEIEDVLNIVEDNNVAY 216
              +++   + N +   +    + +VG E G   A  I+  +E      LN++ D  +A 
Sbjct: 183 KMGSEVYHHLKNVIK-AKFGLDATAVGDEGGF--APNIQSNKE-----ALNLISD-AIAK 233

Query: 217 IKPLGPPELFLELIAGTHGVFIDGEY 242
               G  E+ +++ A     + DG+Y
Sbjct: 234 AGYTGKIEIGMDVAASE--FYKDGQY 257


>sp|P74934|ENO_TREPA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436871|pir||F71278 probable enolase
           (eno) - syphilis spirochete >gi|1575361|gb|AAB39979.1|
           (U61534) 2-phospho-D-glycerate hydrolase [Treponema
           pallidum] >gi|3323125|gb|AAC65781.1| (AE001252) enolase
           (eno) [Treponema pallidum]
           Length = 432
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 54/146 (36%), Positives = 75/146 (50%), Gaps = 15/146 (10%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP-------IEENPMLHIAEAR-- 50
           MS I  I  R ++   G  +VEVDV+  +G FGR   P        E   M    + R  
Sbjct: 1   MSDIACIEAREIIDSRGNPTVEVDVSLSDGSFGRACVPSGASTGEFEALEMRDGDKERYN 60

Query: 51  -----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                +AV  V+ +I   L G DA+ Q  ID  +  +DGT++ S +GAN  L VS+A AR
Sbjct: 61  GKGVLKAVGTVNTLIADTLEGMDALNQGEIDHAMRNLDGTDNKSKLGANAMLGVSMACAR 120

Query: 106 AAANSKDMSLYSYIGGTFATELPVPI 131
           AAA+   + LY Y+GG     +PVP+
Sbjct: 121 AAADFLGVPLYRYLGGVHTFRMPVPM 146


>sp|P07323|ENOG_RAT GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE)
           (NSE) >gi|92215|pir||A24742 phosphopyruvate hydratase
           (EC 4.2.1.11) gamma - rat >gi|204042|gb|AAA41119.1|
           (M11931) neuron-specific enolase [Rattus norvegicus]
           >gi|1619609|emb|CAA30556.1| (X07727) enol_cds [Rattus
           norvegicus] >gi|2465396|gb|AAB72088.1| (AF019973)
           neuron-specific enolase [Rattus norvegicus]
           >gi|225406|prf||1302225A enolase gamma,neuron specific
           [Rattus norvegicus]
           Length = 434
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 54/146 (36%), Positives = 75/146 (50%), Gaps = 19/146 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           IQ I  R ++   G  +VEVD+ T +G  R A P   +  ++ A E R            
Sbjct: 3   IQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  ++  I P LI  G   VEQE +D+ + E+DGTE+ S  GAN  L VS+A+ +A 
Sbjct: 63  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130
           A  KD+ LY +I    G     LPVP
Sbjct: 123 AAEKDLPLYRHIAQLAGNSDLILPVP 148


>emb|CAC16971.1| (AL450350) enolase [Streptomyces coelicolor]
           Length = 434
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 50/150 (33%), Positives = 76/150 (50%), Gaps = 15/150 (10%)

Query: 2   SVIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPI--------------EENPMLHI 46
           + I+ +  R ++   G  +VEVDV  ++G  GR A P               E+    H 
Sbjct: 10  AAIETVTARRIIDSRGNPTVEVDVVLEDGSLGRAAVPSGASTGAREAVELRDEDPTRWHG 69

Query: 47  AEARRAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARA 106
               RAV+ V+  I   + G DA +Q  +D+ L  +DGT   S +GAN  L VS+A A+A
Sbjct: 70  KGVDRAVAHVNGEIAASVRGRDAADQAGLDAALIALDGTAAKSRLGANALLGVSLAAAKA 129

Query: 107 AANSKDMSLYSYIGGTFATELPVPIIQFAS 136
           AA ++   LY Y+GG  A  LP+P++   +
Sbjct: 130 AAAARRQPLYRYLGGADAHLLPLPMMNIVN 159


>sp|P43806|ENO_HAEIN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|1074058|pir||E64103 phosphopyruvate
           hydratase (EC 4.2.1.11) - Haemophilus influenzae (strain
           Rd KW20) >gi|1573953|gb|AAC22590.1| (U32775) enolase
           (eno) [Haemophilus influenzae Rd]
           Length = 436
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 109/429 (25%), Positives = 179/429 (41%), Gaps = 92/429 (21%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGF-GRFASPIEENPMLHIA-EAR-------- 50
           M+ I  +IGR ++   G  +VE +V    GF G  A+P   +     A E R        
Sbjct: 1   MAKIVKVIGREIIDSRGNPTVEAEVHLXGGFVGLAAAPSGASTGSREALELRDGDKSRFL 60

Query: 51  -----RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIAR 105
                +AV+ V+  I   ++G DA  Q  ID  + ++DGTE+ S+ GAN  LAVS+A A+
Sbjct: 61  GKGVLKAVAAVNNEIAQAIVGKDATNQAEIDQIMIDLDGTENKSNFGANAILAVSLANAK 120

Query: 106 AAANSKDMSLYSYI----GGTFATELPVPIIQFA-----SDENF---EYYI------LVR 147
           AAA SK + LY+YI    G      +P+P++        +D N    E+ I       +R
Sbjct: 121 AAAASKGLPLYAYIAELNGTAGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLR 180

Query: 148 DLLEV-TDIVDAVNKIISEVGNKVSIEE-----------------LSKASESVGMELGLE 189
           + L +  ++   + K++   G   ++ +                 + +A E  G  LG +
Sbjct: 181 EALRIGAEVFHNLAKVLKAKGMSTAVGDEGGFAPNLASNADALACIKEAVEKAGYVLGKD 240

Query: 190 VALGI---------------KMKRE---LEIEDVLNIVEDNNVAYIKPL-----GPPELF 226
           V L +               +MK E      ++  + +E+    Y  P+     G  E  
Sbjct: 241 VTLAMDCASSEFYNKENGMYEMKGEGKSFTSQEFTHYLEELCKEY--PIVSIEDGQDESD 298

Query: 227 LELIAGTHGVFID-----GEYLFRANNI-----LDRRYYNALSIKPINLGTLTDLYNFVN 276
            E  A    V  D     G+ LF  N       +++   N++ IK   +G+LT+    + 
Sbjct: 299 WEGFAYQTKVLGDRVQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIK 358

Query: 277 DVKSEKITPILAEAKYEPADDTFPHLALG-----LRCPAMLISWNSVEKINELNRIAEEL 331
             K    T +++    E  D T   LA+G     ++  +M  S + + K N+L RI E L
Sbjct: 359 MAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRS-DRIAKYNQLIRIEEAL 417

Query: 332 GERGRIITF 340
              G    F
Sbjct: 418 ERAGTPAAF 426


>sp|P08734|ENO_XENLA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|68307|pir||NOXL phosphopyruvate
           hydratase (EC 4.2.1.11) ENO1 - African clawed frog
           >gi|64680|emb|CAA68706.1| (Y00718) enolase (AA 1-434)
           [Xenopus laevis]
           Length = 434
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 105/426 (24%), Positives = 169/426 (39%), Gaps = 99/426 (23%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           I+NI  R +    G  +VEVD+ T +G  R A P   +  ++ A E R            
Sbjct: 3   IKNIRAREIFDSRGNPTVEVDLYTCKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGV 62

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            RAV  V+E +GP L     + VEQE ID  + E+DGTE+ S  GAN  L VS+A+ +A 
Sbjct: 63  GRAVKYVNEFLGPALCTQNLNVVEQEKIDKLMIEMDGTENKSKFGANALLGVSLAVCKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVP---------------------IIQFASDE----- 138
           A  K + LY +I    G     LPVP                     I+   +D      
Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGADSFKEAM 182

Query: 139 --NFEYYILVRDLL------EVTDIVDAVNKIISEVGNKVSIEELSKASESVG----MEL 186
               E Y  +++++      + T++ D      + + NK ++E L  A    G    + +
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAINKAGYPDKIVI 242

Query: 187 GLEVALG---IKMKRELEIEDVLNIVEDNNVAYIKPLGPPELFLELI------------- 230
           G++VA        K +L+ +       D+   YI P    EL++  +             
Sbjct: 243 GMDVAASEFYRDGKYDLDFKS-----PDDPSRYISPDKLAELYMSFVKNYPVVSIEDPFD 297

Query: 231 ----------AGTHGVFIDGEYLFRAN-----NILDRRYYNALSIKPINLGTLTDLYNFV 275
                         G+ + G+ L   N       ++ +  N L +K   +GT+T+     
Sbjct: 298 QDHWEAWTKFTAASGIQVVGDDLTVTNPKRIAKAVEEKACNCLLLKVNQIGTVTESLEAC 357

Query: 276 NDVKSEKITPILAEAKYEPADDTFPHLALGLRCPAMLISW-----NSVEKINELNRIAEE 330
              +S     +++    E  D     L +GL C   + +        + K N+L RI EE
Sbjct: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGL-CTGQIKTGAPCRSERLAKYNQLLRIEEE 416

Query: 331 LGERGR 336
           LG + R
Sbjct: 417 LGSKAR 422


>sp|O52191|ENO_STRTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|2921237|gb|AAC64907.1| (AF027167)
           enolase [Streptococcus thermophilus]
           Length = 422
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 102/414 (24%), Positives = 162/414 (38%), Gaps = 89/414 (21%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVA-TDEGFGRFASPI------EENPMLHIAEAR------ 50
           I+NI  R +    G  +VEVDV  TD   GR A P        E   L    AR      
Sbjct: 5   IENIHAREIFDSRGNPTVEVDVRLTDGTLGRAAVPSGASTGDREAVELRDGGARLQGKGV 64

Query: 51  -RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109
            +AV+ V+  I   L G     Q  +D  + E+DGTE+ S +GAN  L VS+AI RAAAN
Sbjct: 65  SKAVANVNGEIYEALKGQSPFNQAKLDHLMIELDGTENKSCLGANAILGVSMAIFRAAAN 124

Query: 110 SKDMSLYSYIGGTFATELPVPIIQFASD----------ENFEYYILVRD-----LLEVTD 154
           S+ + LY Y GG    ELP P     +           + F    + RD     L ++ +
Sbjct: 125 SEKIPLYRYFGGV-DLELPQPFFNVINGGVHADSGIDVQEFLITPVKRDSFRDGLKKIAN 183

Query: 155 IVDAVNKIISEVGNKVSIEE-----------------LSKASESVGMELGLEVALGIKM- 196
           I   + KI+S+ G K  + +                 L +  +S G   G ++A+ I   
Sbjct: 184 IYHTLKKILSDKGLKTPVGDEGGFAPKLGTTENAIAILYQPIDSAGYFPGEKIAIAIDSS 243

Query: 197 -------KRELEIEDVLNIVEDNNVAYIKPLGPPELFLELIAGTHG-------------- 235
                  K++    +  N+     + Y   L   E +  LI+   G              
Sbjct: 244 SIEFYDDKKKFYRFEGKNLTSKELLTYYDNL--VEKYPALISIEDGFSEHDWEGFAAQTK 301

Query: 236 ------------VFIDGEYLFRANNILDRRYYNALSIKPINLGTLTDLYNFVNDVKSEKI 283
                       +F+    +F+    + +   NA+ IK   +GT+T+    ++  +    
Sbjct: 302 ARGQKIQLVGDDIFVTNPTIFKEG--IKKNVANAILIKLNQIGTVTETIETISLARKAGY 359

Query: 284 TPILAEAKYEPADDTFPHLALGLRC----PAMLISWNSVEKINELNRIAEELGE 333
             +++    E  D      ++ +         +     VEK N+L RI E+LG+
Sbjct: 360 KTMISHRSGETVDSYIADFSVAMHAGQIKSGSMARSERVEKYNQLLRIEEDLGK 413


>emb|CAB94039.1| (AL358652) enolase [Leishmania major]
           Length = 429
           
 Score = 72.2 bits (174), Expect = 8e-12
 Identities = 51/144 (35%), Positives = 77/144 (53%), Gaps = 17/144 (11%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-------EAR------ 50
           I+ +  R V+   G  +VEV++ T+ G  R A P   +  +H A       +AR      
Sbjct: 3   IRKVYAREVLDSRGNPTVEVELMTEAGVFRSAVPSGASTGVHEACELRDGDKARYCGAGC 62

Query: 51  -RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109
            +AV  V+EI+ P L+G +  +Q  +D  + E+DGT++ S +GAN  L  S+AI++AAA 
Sbjct: 63  TQAVKNVNEILAPALVGKEESDQAGLDKMMCELDGTKNKSKLGANAILGCSMAISKAAAA 122

Query: 110 SKDMSLYSYI---GGTFATELPVP 130
              + LY YI    GT    LPVP
Sbjct: 123 KAGVPLYRYIASLAGTKDIRLPVP 146


>pir||S43113 phosphopyruvate hydratase (EC 4.2.1.11) - fungus  (Cladosporium
           herbarum) >gi|467660|emb|CAA55070.1| (X78226)
           phosphopyruvate hydratase [Cladosporium herbarum]
           Length = 440
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 54/149 (36%), Positives = 77/149 (51%), Gaps = 20/149 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           I  I  R V    G  +VEVD+ T+ G  R   P   +   H A E R            
Sbjct: 3   ISKIHSRYVYDSRGNPTVEVDIVTETGLHRAIVPSVASTGSHEACELRDGDKSKWAGKGV 62

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV+ V+EII P LI    D  +Q  +D++L ++DGT + + IGAN  L VS+A+A+AA
Sbjct: 63  TKAVANVNEIIAPALIKENLDVKDQAAVDAFLNKLDGTTNKTKIGANAILGVSMAVAKAA 122

Query: 108 ANSKDMSLYSYIGGTFATE----LPVPII 132
           A  K + LY++I     T+    LPVP +
Sbjct: 123 AAEKRVPLYAHISDLSGTKKPFVLPVPFM 151


>sp|P07322|ENOB_CHICK BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (PHOSPHOPYRUVATE
           HYDRATASE) >gi|1085244|pir||JC4187 phosphopyruvate
           hydratase (EC 4.2.1.11) beta chain - chicken
           >gi|1616990|dbj|BAA07133.1| (D37901) enolase [Gallus
           gallus]
           Length = 434
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 55/148 (37%), Positives = 76/148 (51%), Gaps = 17/148 (11%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           IQ I  R ++   G  +VEVD+ T +G  R A P   +  +H A E R            
Sbjct: 3   IQKIHAREILDSRGEPTVEVDLHTAKGHFRAAVPSGASTGIHEALEPRDGDKKRFLGKGV 62

Query: 51  -RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  +++ IGP LI      VEQE ID  + E+DGTE+ S  GAN  L VS+A+ +A 
Sbjct: 63  LKAVEHINKTIGPALIEKKISVVEQEKIDKVMIEMDGTENKSKFGANAILGVSLAVCKAG 122

Query: 108 ANSKDMSLYSYIGGTFA-TELPVPIIQF 134
           A  K + LY +I      TEL +P+  F
Sbjct: 123 AAEKGVPLYRHIADLAGNTELILPVPAF 150


>sp|P42040|ENO_CLAHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) (ALLERGEN CLA H 6) (CLA H VI)
           Length = 440
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 54/149 (36%), Positives = 77/149 (51%), Gaps = 20/149 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           I  I  R V    G  +VEVD+ T+ G  R   P   +   H A E R            
Sbjct: 3   ISKIHSRYVYDSRGNPTVEVDIVTETGLHRAIVPSGASTGSHEACELRDGDKSKWAGKGV 62

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV+ V+EII P LI    D  +Q  +D++L ++DGT + + IGAN  L VS+A+A+AA
Sbjct: 63  TKAVANVNEIIAPALIKENLDVKDQAAVDAFLNKLDGTTNKTKIGANAILGVSMAVAKAA 122

Query: 108 ANSKDMSLYSYIGGTFATE----LPVPII 132
           A  K + LY++I     T+    LPVP +
Sbjct: 123 AAEKRVPLYAHISDLSGTKKPFVLPVPFM 151


>pir||T39737 enolase - fission yeast (Schizosaccharomyces pombe)
           >gi|4886570|emb|CAB43486.1| (AL050301) enolase
           [Schizosaccharomyces pombe] >gi|6579195|gb|AAA51399.2|
           (L37084) phosphopyruvate hydratase [Schizosaccharomyces
           pombe]
           Length = 439
           
 Score = 71.4 bits (172), Expect = 1e-11
 Identities = 50/147 (34%), Positives = 71/147 (48%), Gaps = 20/147 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51
           IQ +  R +    G  +VEVD+ T+ G  R   P   +  +  A   R            
Sbjct: 3   IQKVFARQIYDSRGNPTVEVDLTTETGIHRAIVPSGASTGIWEALEMRDGDKTKWGGKGV 62

Query: 52  --AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
             AV  V+ II P ++    D  +Q+  D +L ++DGTE+ S +GAN  L VS+AI RA 
Sbjct: 63  LKAVGNVNNIIAPAVVKANLDVTDQKAADEFLLKLDGTENKSKLGANAILGVSMAICRAG 122

Query: 108 ANSKDMSLYSYIGGTFATE----LPVP 130
           A  K + L+ YI   F T+    LPVP
Sbjct: 123 AAQKKLPLWKYIAENFGTKGPYVLPVP 149


>pir||JC1039 phosphopyruvate hydratase (EC 4.2.1.11) - rat
           Length = 434
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 53/146 (36%), Positives = 75/146 (51%), Gaps = 19/146 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           IQ I  R ++   G  +VEVD+ T +G  R A P   +  ++ A E R            
Sbjct: 3   IQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  ++  I P LI  G   VEQE +D+ + E+DGTE+ S  GAN  L VS+A+ +A 
Sbjct: 63  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130
           A  K++ LY +I    G     LPVP
Sbjct: 123 AAEKNLPLYRHIAQLAGNSDLILPVP 148


>gb|AAB87890.1| (AF025805) enolase [Drosophila pseudoobscura]
           Length = 413
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 44/128 (34%), Positives = 69/128 (53%), Gaps = 19/128 (14%)

Query: 22  EVDVATDEGFGRFASPIEENPMLHIA--------------EARRAVSEVDEIIGPELI-- 65
           EVD+ T+ G  R A P   +  +H A                 +AV+ V++ +GPE+I  
Sbjct: 1   EVDLTTENGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVAHVNDTLGPEVIKA 60

Query: 66  GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYI---GGT 122
             D V+Q  +D+++ ++DGTE+ S  GAN  L +S+A+A+A A  K++ LY +I    G 
Sbjct: 61  NLDVVDQAAVDNFMIKLDGTENKSKFGANAILGISLAVAKAGAAKKNVPLYKHIADLAGN 120

Query: 123 FATELPVP 130
               LPVP
Sbjct: 121 KEIILPVP 128


>gb|AAB87891.1| (AF025806) enolase [Drosophila subobscura]
           Length = 413
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 44/128 (34%), Positives = 69/128 (53%), Gaps = 19/128 (14%)

Query: 22  EVDVATDEGFGRFASPIEENPMLHIA--------------EARRAVSEVDEIIGPELI-- 65
           EVD+ T+ G  R A P   +  +H A                 +AV+ V++ +GPE+I  
Sbjct: 1   EVDLTTEHGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVAHVNDTLGPEVIKA 60

Query: 66  GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANSKDMSLYSYI---GGT 122
             D V+Q  +D+++ ++DGTE+ S  GAN  L +S+A+A+A A  K++ LY +I    G 
Sbjct: 61  NLDVVDQAAVDNFMIKLDGTENKSKFGANAILGISLAVAKAGAAKKNVPLYKHIADLAGN 120

Query: 123 FATELPVP 130
               LPVP
Sbjct: 121 KEIILPVP 128


>pir||A23850 phosphopyruvate hydratase (EC 4.2.1.11), skeletal muscle - chicken
           Length = 433
           
 Score = 70.6 bits (170), Expect = 2e-11
 Identities = 55/148 (37%), Positives = 76/148 (51%), Gaps = 17/148 (11%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           IQ I  R ++   G  +VEVD+ T +G  R A P   +  +H A E R            
Sbjct: 2   IQKIHAREILDSRGDPTVEVDLHTAKGHFRAAVPSGASTGIHEALELRDGDKKRFLGKGV 61

Query: 51  -RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  +++ IGP LI      VEQE ID  + E+DGTE+ S  GAN  L VS+A++ A 
Sbjct: 62  LKAVEHINKTIGPALIEKKISVVEQEKIDKVVIEMDGTENKSKFGANAILGVSLAVSHAG 121

Query: 108 ANSKDMSLYSYIGGTFA-TELPVPIIQF 134
           A  K + LY +I      TEL +P+  F
Sbjct: 122 AAEKGVPLYRHIADLAGNTELILPVPAF 149


>gb|AAD45339.1|AF159529_1 (AF159529) enolase [Trypanosoma brucei]
           Length = 370
           
 Score = 70.6 bits (170), Expect = 2e-11
 Identities = 37/83 (44%), Positives = 54/83 (64%), Gaps = 3/83 (3%)

Query: 51  RAVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAANS 110
           +AV  V+E+IGP LIG D ++QE +D+ +  +DGT +   +GAN  L  S+AI++AAA +
Sbjct: 41  QAVKNVNEVIGPALIGRDELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISKAAAAA 100

Query: 111 KDMSLYSY---IGGTFATELPVP 130
           K + LY Y   + GT    LPVP
Sbjct: 101 KGVPLYRYLASLAGTKELRLPVP 123


>gb|AAF36733.1| (AC016662) putative enolase; 31277-33713 [Arabidopsis thaliana]
           Length = 477
           
 Score = 70.6 bits (170), Expect = 2e-11
 Identities = 46/146 (31%), Positives = 78/146 (52%), Gaps = 16/146 (10%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51
           ++ +  R ++   G  +VEVD+ TD+ + R A P   +  ++ A   R            
Sbjct: 51  VKGVKARQIIDSRGNPTVEVDLITDDLY-RSAVPSGASTGIYEALELRDGDKSVYGGKGV 109

Query: 52  --AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAAN 109
             A+  ++E++ P+LIG D   Q  +D+ + E+DGT + S +GAN  L VS+++ RA A 
Sbjct: 110 LQAIKNINELVAPKLIGVDVRNQADVDALMLELDGTPNKSKLGANAILGVSLSVCRAGAG 169

Query: 110 SKDMSLYSYIGGTFAT-ELPVPIIQF 134
           +K + LY +I  T  T EL +P+  F
Sbjct: 170 AKGVPLYKHIQETSGTKELVMPVPAF 195


>emb|CAA31512.1| (X13120) neurone-specific enolase [Homo sapiens]
           >gi|930101|emb|CAA32505.1| (X14327) gamma enolase [Homo
           sapiens]
           Length = 433
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 52/146 (35%), Positives = 75/146 (50%), Gaps = 19/146 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           IQ I  R ++   G  +VEVD+ T +G  R A P   +  ++ A E R            
Sbjct: 2   IQKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 61

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  ++  I P LI  G   VEQE +D+ + E+DGTE+ S  GAN  L VS+A+ +A 
Sbjct: 62  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 121

Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130
           A  +++ LY +I    G     LPVP
Sbjct: 122 AAERELPLYRHIAQLAGNSDLILPVP 147


>pir||E81654 enolase TC0876 [imported] - Chlamydia muridarum (strain Nigg)
           >gi|7190904|gb|AAF39672.1| (AE002354) enolase [Chlamydia
           muridarum]
           Length = 424
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 48/145 (33%), Positives = 77/145 (53%), Gaps = 15/145 (10%)

Query: 3   VIQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASP------IEENPMLHIAEARR---- 51
           VI +I  R ++   G  ++ V V T+ G FG    P      I+E   L   + +R    
Sbjct: 5   VISDIEAREILDSRGYPTLYVKVITNTGIFGEACVPSGASTGIKEALELRDQDPKRYQGK 64

Query: 52  ----AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
               AV+ V++++ P L GF   +Q   D+ + + DGT +   +GAN  L VS+A+A+AA
Sbjct: 65  GVLQAVANVEKVLLPALQGFSVFDQITADAIMIDADGTSNKEKLGANAILGVSLALAKAA 124

Query: 108 ANSKDMSLYSYIGGTFATELPVPII 132
           A + +  LY Y+GG F+  LP P++
Sbjct: 125 AATLERPLYRYLGGAFSHVLPCPMM 149


>sp|P09104|ENOG_HUMAN GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE)
           (NSE)
           Length = 434
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 52/146 (35%), Positives = 75/146 (50%), Gaps = 19/146 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           IQ I  R ++   G  +VEVD+ T +G  R A P   +  ++ A E R            
Sbjct: 3   IQKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  ++  I P LI  G   VEQE +D+ + E+DGTE+ S  GAN  L VS+A+ +A 
Sbjct: 63  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130
           A  +++ LY +I    G     LPVP
Sbjct: 123 AAERELPLYRHIAQLAGNSDLILPVP 148


>gi|7305027 enolase 2, gamma neuronal [Mus musculus]
           >gi|119348|sp|P17183|ENOG_MOUSE GAMMA ENOLASE
           (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE)
           (NSE) >gi|109805|pir||S10247 phosphopyruvate hydratase
           (EC 4.2.1.11) gamma - mouse >gi|55495|emb|CAA36606.1|
           (X52380) gamma-enolase (AA 1-434) [Mus sp.]
           >gi|2289903|gb|AAC36002.1| (AC002397) ENO2 [Mus
           musculus]
           Length = 434
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 52/146 (35%), Positives = 75/146 (50%), Gaps = 19/146 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           I+ I  R ++   G  +VEVD+ T +G  R A P   +  ++ A E R            
Sbjct: 3   IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  ++  I P LI  G   VEQE +D+ + E+DGTE+ S  GAN  L VS+A+ +A 
Sbjct: 63  LKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130
           A  +D+ LY +I    G     LPVP
Sbjct: 123 AAERDLPLYRHIAQLAGNSDLILPVP 148


>gb|AAC47640.1| (U85826) enolase [Haematoloechus sp.]
           Length = 168
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 52/145 (35%), Positives = 76/145 (51%), Gaps = 18/145 (12%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           I+ I  R +    G  +VEVDV TD+G  R A P   +  +H A E R            
Sbjct: 3   IKKIHARQIFDSRGNPTVEVDVFTDKGTFRAAVPSGASTGVHEALELRDGGKTYMGKAVL 62

Query: 51  RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAA 108
           +A+S V++ I PELI       +Q  ID+++ ++DGT++ + +GAN  L VS+A+ +A A
Sbjct: 63  KAISNVNDKIAPELIKANIPVTDQTAIDNFMIKLDGTKNKATLGANAILGVSLAVCKAGA 122

Query: 109 NSKDMSLYSYI---GGTFATELPVP 130
             K + LY YI    G     LPVP
Sbjct: 123 AEKGVPLYRYIASLAGNNDVILPVP 147


>gb|AAC47641.1| (U85828) enolase [Lacistorhynchus tenuis]
           Length = 169
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 50/146 (34%), Positives = 73/146 (49%), Gaps = 19/146 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51
           I+ I  R +    G  +VEVD+ T +G  R A P   +  +H A   R            
Sbjct: 3   IKTIHARQIFDSRGNPTVEVDLTTAKGMFRAAVPSGASTGVHEAVELRDGVKNQYMGKGV 62

Query: 52  --AVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
             AV  V++I+GPELI  G    EQ  +D ++ ++DGT++   +GAN  L VS+A+ +A 
Sbjct: 63  LKAVDNVNKILGPELIKSGIAVTEQVKVDEFMKKLDGTDNKGKLGANAILGVSLAVCKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130
           A  K + LY +I    G     LPVP
Sbjct: 123 AAEKGIPLYRHIANLAGNKEIVLPVP 148


>gb|AAC46289.1| (AF000366) enolase homolog [Borrelia burgdorferi]
           Length = 433
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 49/143 (34%), Positives = 69/143 (47%), Gaps = 15/143 (10%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR----------- 51
           I  I  R ++   G  +VE DV  ++G +GR A P   +  ++ A   R           
Sbjct: 5   IYEIKARQIIDSRGNPTVEADVILEDGTYGRAAVPSGASTGINEAVELRDGDKSVYMGKG 64

Query: 52  ---AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAA 108
              A+  +  II PEL G  A+ Q  ID  + E+DGT     +GAN  LAVS+A A+AAA
Sbjct: 65  VLKAIENIKNIIAPELEGMSALNQVAIDRKMLELDGTPTKEKLGANAILAVSMATAKAAA 124

Query: 109 NSKDMSLYSYIGGTFATELPVPI 131
               +  Y Y+G   A  LP P+
Sbjct: 125 KYLGLRPYQYLGAYKANILPTPM 147


>sp|O51312|ENO_BORBU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436876|pir||H70141 enolase (eno)
           homolog - Lyme disease spirochete
           >gi|2688240|gb|AAC66719.1| (AE001140) enolase (eno)
           [Borrelia burgdorferi]
           Length = 433
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 49/143 (34%), Positives = 69/143 (47%), Gaps = 15/143 (10%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEG-FGRFASPIEENPMLHIAEARR----------- 51
           I  I  R ++   G  +VE DV  ++G +GR A P   +  ++ A   R           
Sbjct: 5   IYEIKARQIIDSRGNPTVEADVILEDGTYGRAAVPSGASTGINEAVELRDGDKSVYMGKG 64

Query: 52  ---AVSEVDEIIGPELIGFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAAA 108
              A+  +  II PEL G  A+ Q  ID  + E+DGT     +GAN  LAVS+A A+AAA
Sbjct: 65  VLKAIENIKNIIAPELEGMSALNQVAIDRKMLELDGTPTKEKLGANAILAVSMATAKAAA 124

Query: 109 NSKDMSLYSYIGGTFATELPVPI 131
               +  Y Y+G   A  LP P+
Sbjct: 125 KYLGLRPYQYLGAYKANILPTPM 147


>sp|P42894|ENO_NEOFR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|515827|emb|CAA56645.1| (X80474) enolase
           [Neocallimastix frontalis]
           Length = 436
           
 Score = 69.5 bits (167), Expect = 5e-11
 Identities = 50/147 (34%), Positives = 74/147 (50%), Gaps = 20/147 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           I  +  R +    G  +VEV+V TD+G  R A P   +  +H A E R            
Sbjct: 3   ITKVHARQIFDSRGNPTVEVEVTTDKGLFRAAVPSGASTGVHEALELRDGIKADYVGKGV 62

Query: 51  -RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  V++ I P L+    D   Q+ +D +L ++DGT + S +GAN  L VS+A+ARA 
Sbjct: 63  LKAVENVNKTIAPALVAANLDVKNQKAVDDFLLKLDGTPNKSKLGANAILGVSLAVARAG 122

Query: 108 ANSKDMSLYSYIGGTFATE----LPVP 130
           A  K + LY ++G     +    LPVP
Sbjct: 123 AADKGVPLYQHLGELAGNKGPWILPVP 149


>gi|5803011 enolase 2, (gamma, neuronal); Enolase-2, gamma, neuronal [Homo
           sapiens] >gi|11436317|ref|XP_006974.1| enolase 2,
           (gamma, neuronal) [Homo sapiens] >gi|68305|pir||NOHUG
           phosphopyruvate hydratase (EC 4.2.1.11) gamma - human
           >gi|31165|emb|CAA36215.1| (X51956) human gamma enolase
           [Homo sapiens] >gi|182116|gb|AAB59554.1| (M22349)
           enolase [Homo sapiens] >gi|1732416|gb|AAB51320.1|
           (U47924) neuron specific gamma-enolase [Homo sapiens]
           Length = 434
           
 Score = 69.1 bits (166), Expect = 7e-11
 Identities = 51/146 (34%), Positives = 75/146 (50%), Gaps = 19/146 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR------------ 50
           I+ I  R ++   G  +VEVD+ T +G  R A P   +  ++ A E R            
Sbjct: 3   IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 51  -RAVSEVDEIIGPELI--GFDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
            +AV  ++  I P LI  G   VEQE +D+ + E+DGTE+ S  GAN  L VS+A+ +A 
Sbjct: 63  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130
           A  +++ LY +I    G     LPVP
Sbjct: 123 AAERELPLYRHIAQLAGNSDLILPVP 148


>sp|P30575|ENO1_CANAL ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|422073|pir||A40624 phosphopyruvate
           hydratase (EC 4.2.1.11) - yeast (Candida albicans)
           >gi|170861|gb|AAB46358.1| (L04943) enolase [Candida
           albicans] >gi|170863|gb|AAA71939.1| (L10290) enolase
           [Candida albicans] >gi|170865|gb|AAA34341.1| (M93712)
           enolase [Candida albicans]
           Length = 440
           
 Score = 68.7 bits (165), Expect = 9e-11
 Identities = 57/153 (37%), Positives = 75/153 (48%), Gaps = 25/153 (16%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR--------- 50
           MS    I  R V    G  +VEVD  TD+G  R   P   +  +H A E R         
Sbjct: 1   MSYATKIHARYVYDSRGNPTVEVDFTTDKGLFRSIVPSGASTGVHEALELRDGDKSKWLG 60

Query: 51  ----RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIA 104
               +AV+ V++II P LI    D V+Q  ID +L  +DGT + S +GAN  L VS+A A
Sbjct: 61  KGVLKAVANVNDIIAPALIKAKIDVVDQAKIDEFLLSLDGTPNKSKLGANAILGVSLAAA 120

Query: 105 RAAANSKDMSLYSYIG-------GTFATELPVP 130
            AAA ++ + LY +I        G F   LPVP
Sbjct: 121 NAAAAAQGIPLYKHIANISNAKKGKFV--LPVP 151


>gi|6323985 Ymr323wp [Saccharomyces cerevisiae]
           >gi|1706698|sp|P42222|ERR1_YEAST ENOLASE RELATED PROTEIN
           1 >gi|2118301|pir||S69881 phosphopyruvate hydratase (EC
           4.2.1.11) YMR323w - yeast  (Saccharomyces cerevisiae)
           >gi|1072413|emb|CAA90841.1| (Z54141) unknown
           [Saccharomyces cerevisiae]
           Length = 437
           
 Score = 68.7 bits (165), Expect = 9e-11
 Identities = 48/132 (36%), Positives = 65/132 (48%), Gaps = 16/132 (12%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51
           I  +  R V    G  +VEV++ T+ G  R   P   +  +H A   R            
Sbjct: 3   ITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGV 62

Query: 52  --AVSEVDEIIGPELIGFD--AVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
             AVS V+ IIGP LI  D     Q+ ID  +  +DGT + S +GAN  L VS+ +ARAA
Sbjct: 63  TKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAA 122

Query: 108 ANSKDMSLYSYI 119
           A  K ++LY YI
Sbjct: 123 AAQKGITLYKYI 134


>gb|AAC47638.1| (U85827) enolase [Hydra cf. oligactis]
           Length = 173
           
 Score = 68.7 bits (165), Expect = 9e-11
 Identities = 52/149 (34%), Positives = 75/149 (49%), Gaps = 19/149 (12%)

Query: 1   MSVIQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIA-EAR--------- 50
           M+ I  I  R ++   G  +VEVD+ T  G  R A P   +  +H A E R         
Sbjct: 1   MAPITKIHAREILDSTGNPTVEVDLTTPLGTFRAAVPSGASTGIHEALELRDKDPKRYLG 60

Query: 51  ----RAVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIA 104
               +AV  V+EII P LI    D  +Q+ +D  + E+DGT + S +GAN  L VS+A++
Sbjct: 61  KGVTKAVENVNEIIAPYLISKNIDCTKQKEVDQLMIELDGTPNKSKLGANATLGVSLAVS 120

Query: 105 RAAANSKDMSLYSYIGGTFATE---LPVP 130
           +A A  K + LY ++      E   LPVP
Sbjct: 121 KAGAAQKGVPLYKHLADLAGNENLILPVP 149


>sp|O57391|ENOG_CHICK GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE)
           (NSE) >gi|2842531|dbj|BAA24680.1| (AB004291)
           gamma-subunit of enolase [Gallus gallus]
           Length = 434
           
 Score = 68.7 bits (165), Expect = 9e-11
 Identities = 48/146 (32%), Positives = 73/146 (49%), Gaps = 19/146 (13%)

Query: 4   IQNIIGRVVVLRGGMYSVEVDVATDEGFGRFASPIEENPMLHIAEARR------------ 51
           ++ I  R ++   G  +VEVD+ T +G  R A P   +  ++ A   R            
Sbjct: 3   VERIHAREILDSRGNPTVEVDLYTHKGMFRAAVPSGASTGIYEALELRDNDKSRFLGKGV 62

Query: 52  --AVSEVDEIIGPELIG--FDAVEQELIDSYLWEIDGTEDFSHIGANTALAVSIAIARAA 107
             AV  ++  + P ++G     V+QE ID+ + E+DGTE+ S  GAN  L VS+A+ +A 
Sbjct: 63  LQAVDHINSTVAPAIVGSGLSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAG 122

Query: 108 ANSKDMSLYSYI---GGTFATELPVP 130
           A  KD+ LY +I    G     LPVP
Sbjct: 123 AAEKDVPLYRHIADLAGNSDLILPVP 148


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.318    0.139    0.385 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 121507069
Number of Sequences: 2977
Number of extensions: 5045219
Number of successful extensions: 13373
Number of sequences better than 1.0e-10: 80
Number of HSP's better than  0.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 13233
Number of HSP's gapped (non-prelim): 140
length of query: 342
length of database: 189,106,746
effective HSP length: 58
effective length of query: 284
effective length of database: 154,394,500
effective search space: 43848038000
effective search space used: 43848038000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 165 (68.7 bits)