BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0369 (thrC-like) DE:related threonine synthase (thrC-2)
(343 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75172 probable threonine synthase (EC 4.2.99.2) thrc-2 PAB... 693 0.0
pir||C71042 probable threonine synthase (EC 4.2.99.2) PH1627 [si... 554 e-157
gb|AAK40813.1| Threonine synthase (thrC-1) [Sulfolobus solfatari... 189 6e-47
emb|CAC11637.1| (AL445064) threonine synthase related protein [T... 173 3e-42
pir||G75080 threonine synthase (EC 4.2.99.2) thrc-2 PAB1677 [sim... 173 4e-42
gb|AAG20250.1| (AE005100) threonine synthase; ThrC3 [Halobacteri... 172 6e-42
pir||E71136 threonine synthase (EC 4.2.99.2) PH0857 [similarity]... 169 4e-41
gb|AAK41164.1| Threonine synthase (thrC-2) [Sulfolobus solfatari... 161 1e-38
sp|Q58860|THRC_METJA PROBABLE THREONINE SYNTHASE >gi|2118306|pir... 160 2e-38
pir||H72628 probable threonine synthase (EC 4.2.99.2) APE1488 [s... 159 6e-38
pir||E75118 probable threonine synthase (EC 4.2.99.2) thrc-2 PAB... 152 4e-36
pir||H71013 probable threonine synthase (EC 4.2.99.2) PH1406 [si... 149 4e-35
pir||B72455 threonine synthase (EC 4.2.99.2) APE2286 [similarity... 146 3e-34
pir||G69131 threonine synthase (EC 4.2.99.2) - Methanobacterium ... 142 7e-33
gi|11498914 threonine synthase (thrC-2) [Archaeoglobus fulgidus]... 135 8e-31
pir||D70354 threonine synthase (EC 4.2.99.2) thrC1 [similarity] ... 134 1e-30
pir||H70338 threonine synthase (EC 4.2.99.2) - Aquifex aeolicus ... 130 2e-29
pir||G72364 threonine synthase (EC 4.2.99.2) TM0546 [similarity]... 130 2e-29
gb|AAG19064.1| (AE005005) threonine synthase; ThrC2 [Halobacteri... 129 4e-29
sp|P74193|THRC_SYNY3 THREONINE SYNTHASE >gi|7436917|pir||S75823 ... 119 4e-26
pir||S77200 threonine synthase (EC 4.2.99.2) 1 - Synechocystis s... 117 2e-25
sp|P04990|THRC_BACSU THREONINE SYNTHASE >gi|80429|pir||A25364 th... 117 2e-25
gb|AAG20514.1| (AE005123) threonine synthase; ThrC1 [Halobacteri... 117 2e-25
sp|Q10610|THRC_MYCTU PROBABLE THREONINE SYNTHASE >gi|7436919|pir... 116 4e-25
sp|P09123|THRC_BRELA THREONINE SYNTHASE >gi|68321|pir||DWFKTG th... 115 6e-25
dbj|BAB07140.1| (AP001518) threonine synthase [Bacillus halodurans] 113 2e-24
emb|CAB93053.1| (AL357432) putative threonine synthase [Streptom... 113 3e-24
gi|11498161 threonine synthase (thrC-1) [Archaeoglobus fulgidus]... 112 7e-24
sp|P45837|THRC_MYCLE PROBABLE THREONINE SYNTHASE >gi|7436934|pir... 110 3e-23
gb|AAF54364.1| (AE003682) CG8129 gene product [alt 1] [Drosophil... 103 3e-21
gb|AAF59508.1| (AC024805) contains similarity to SW:THD2_ECOLI [... 101 1e-20
pir||D72386 threonine dehydratase (EC 4.2.1.16) TM0356 [similari... 99 9e-20
pir||T23166 hypothetical protein K01C8.1 - Caenorhabditis elegan... 95 1e-18
gb|AAD55628.1|AC008017_1 (AC008017) Putative threonine synthase ... 89 1e-16
emb|CAC11175.1| (AL445063) threonine synthase related protein [T... 89 1e-16
pir||S71362 threonine synthase (EC 4.2.99.2) precursor - Arabido... 87 4e-16
pir||T08545 threonine synthase (EC 4.2.99.2) precursor - Arabido... 87 4e-16
gb|AAF74984.1|AF082894_1 (AF082894) threonine synthase [Solanum ... 85 1e-15
pir||D81355 threonine dehydratase (EC 4.2.1.16) Cj0828c [importe... 83 3e-15
gb|AAG20244.1| (AE005099) threonine dehydratase; IluA [Halobacte... 80 5e-14
sp|P46493|THD1_HAEIN THREONINE DEHYDRATASE BIOSYNTHETIC (THREONI... 76 6e-13
pir||E82374 threonine dehydratase VC0027 [imported] - Vibrio cho... 75 2e-12
gi|7305521 serine racemase [Mus musculus] >gi|6448865|gb|AAF0870... 74 3e-12
gi|11345492 serine racemase [Homo sapiens] >gi|10434972|dbj|BAB1... 71 2e-11
gb|AAA67575.1| (M87049) threonine deaminase [Escherichia coli] 69 6e-11
sp|P04968|THD1_ECOLI THREONINE DEHYDRATASE BIOSYNTHETIC (THREONI... 69 7e-11
gb|AAA24014.1| (K03503) threonine dehydratase [Escherichia coli] 69 7e-11
emb|CAC11260.1| (AL445063) probable threonine dehydratase, biode... 69 9e-11
>pir||E75172 probable threonine synthase (EC 4.2.99.2) thrc-2 PAB0369
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5457970|emb|CAB49460.1| (AJ248284) related threonine
synthase (thrC-2) [Pyrococcus abyssi]
Length = 343
Score = 693 bits (1770), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MLVCTKCGRTFDEKFLLRCTCGGTLLVKRHYTSFSPRNYLDMRRYIDYLPVDSVFLPKLT 60
MLVCTKCGRTFDEKFLLRCTCGGTLLVKRHYTSFSPRNYLDMRRYIDYLPVDSVFLPKLT
Sbjct: 1 MLVCTKCGRTFDEKFLLRCTCGGTLLVKRHYTSFSPRNYLDMRRYIDYLPVDSVFLPKLT 60
Query: 61 PAITPIVKDSEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAGISLAA 120
PAITPIVKDSEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAGISLAA
Sbjct: 61 PAITPIVKDSEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAGISLAA 120
Query: 121 YGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSH 180
YGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSH
Sbjct: 121 YGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSH 180
Query: 181 WMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLV 240
WMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLV
Sbjct: 181 WMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLV 240
Query: 241 AVQAEGFESLCKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETLASLHW 300
AVQAEGFESLCKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETLASLHW
Sbjct: 241 AVQAEGFESLCKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETLASLHW 300
Query: 301 LRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGSAKNF 343
LRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGSAKNF
Sbjct: 301 LRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGSAKNF 343
>pir||C71042 probable threonine synthase (EC 4.2.99.2) PH1627 [similarity] -
Pyrococcus horikoshii >gi|3258056|dbj|BAA30739.1|
(AP000006) 346aa long hypothetical threonine synthase
[Pyrococcus horikoshii]
Length = 346
Score = 554 bits (1413), Expect = e-157
Identities = 259/343 (75%), Positives = 302/343 (87%)
Query: 1 MLVCTKCGRTFDEKFLLRCTCGGTLLVKRHYTSFSPRNYLDMRRYIDYLPVDSVFLPKLT 60
ML+C+KCGR F+EKF+LRCTCGGTLLVKR Y SF+PR +LD+RRYIDYLPVD FLP LT
Sbjct: 4 MLICSKCGRKFEEKFILRCTCGGTLLVKRKYDSFAPRKFLDIRRYIDYLPVDEKFLPSLT 63
Query: 61 PAITPIVKDSEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAGISLAA 120
P ITPI K S+++YLKLDYLQPTGSFKDRGTYVT+AK+KEEGI+EVVIDSSGNAG+SLA
Sbjct: 64 PGITPISKISDEVYLKLDYLQPTGSFKDRGTYVTVAKIKEEGIDEVVIDSSGNAGLSLAT 123
Query: 121 YGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSH 180
YG++EGIKVHVFLSY+A EKI+RL+++NA+LHFV+GDRM+VHEEA++FS + Y SH
Sbjct: 124 YGMAEGIKVHVFLSYNAKPEKIARLNSVNARLHFVEGDRMRVHEEAVKFSERTGIPYASH 183
Query: 181 WMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLV 240
W+NPYFLEGTKTIAFEIYEQI +P Y+F+PVGSGTAFLGIWKGFKEL+EMGEI MPSLV
Sbjct: 184 WLNPYFLEGTKTIAFEIYEQIGIPRYIFVPVGSGTAFLGIWKGFKELLEMGEINKMPSLV 243
Query: 241 AVQAEGFESLCKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETLASLHW 300
AVQAEG+ESLCKRSK N LADGIAIP PPRIEEMK A++E+SGFCISVG+EETLA HW
Sbjct: 244 AVQAEGYESLCKRSKSVNKLADGIAIPNPPRIEEMKVALRETSGFCISVGEEETLAGYHW 303
Query: 301 LRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGSAKNF 343
LR+ G +E TSA LA YWKA+E L+ G SLL+LTGSAK+F
Sbjct: 304 LRRNGFFIEETSATALAGYWKAREKGLVKGSSLLLLTGSAKSF 346
>gb|AAK40813.1| Threonine synthase (thrC-1) [Sulfolobus solfataricus]
Length = 345
Score = 189 bits (474), Expect = 6e-47
Identities = 118/350 (33%), Positives = 189/350 (53%), Gaps = 31/350 (8%)
Query: 3 VCTKCGRTFDEKFLLRCT-CGGT--LLVKRHYTSFSPRNYLDMRRYIDYLPVDSVFLPKL 59
VC KC + + + ++C CGG +L+ + S R + + Y+ L
Sbjct: 9 VCMKCRKERESIYEIKCNKCGGPFEILIDFEFDKNSERGFPYSEKIFPYIK----HFISL 64
Query: 60 TPAITPIVKDSEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAGISLA 119
TP++K +++ KLD+L P+GS+KDRG ++ L E+G+ ++ DSSGNAG ++A
Sbjct: 65 GEGRTPLIKKG-NIWFKLDFLNPSGSYKDRGAVTLVSYLAEKGVKQISEDSSGNAGSAIA 123
Query: 120 AYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVS 179
AY + GI+ ++F+ A K+ ++ + A + V G R E+ + + + Y S
Sbjct: 124 AYSAAAGIEAYIFVPETAKGGKLKQIESYGAHVVRVRGSR----EDVAKAAENSGYYYAS 179
Query: 180 HWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMP 237
H + P F +G +T+A+EI + + K+P+YVFIPV +GT LG++KGFK L++ G I MP
Sbjct: 180 HVLQPQFRDGIRTLAYEIVKDLDWKIPNYVFIPVSAGTLLLGVYKGFKHLLDSGVISEMP 239
Query: 238 SLVAVQAEGFESLCKRSK--------RKNTLADGIAIPEPPRIEEMKQAIKESSGFCISV 289
+VAVQ E LC + K + ++AD + P ++ M +A E CI V
Sbjct: 240 KIVAVQTEQVMPLCAKFKKISYTPPDKVTSIADALVSTRPFLLDYMVKASSE----CIVV 295
Query: 290 GKEETLASLHWLRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGS 339
E + + L K G+LVE +SA AAY K+ + D V L+LTGS
Sbjct: 296 SDNEIVEAWKELAKMGLLVEYSSATVFAAY---KKYSVNDAV--LVLTGS 340
>emb|CAC11637.1| (AL445064) threonine synthase related protein [Thermoplasma
acidophilum]
Length = 334
Score = 173 bits (434), Expect = 3e-42
Identities = 117/339 (34%), Positives = 179/339 (52%), Gaps = 38/339 (11%)
Query: 17 LRC-TCGGTLLVKR--HYTSFSPRNYLDMRRYIDYLPVDSVFLPKLTPAITPIVKDSEDL 73
LRC +CG ++ HY N+ ++ I L + TPI +D
Sbjct: 12 LRCKSCGSPFEIRTGFHYRENIEDNFPYIKNMIS-----------LGESETPIFH-GDDF 59
Query: 74 YLKLDYLQPTGSFKDRGTYVTIAKLKE----EGINEVVIDSSGNAGISLAAYGLSEGIKV 129
LKLDY+ PT S+KDRG+ + I+ + + GI + DSSGNAG S+AAYG + G+ V
Sbjct: 60 DLKLDYMLPTFSYKDRGSRILISHIADIRDSYGITRISEDSSGNAGASIAAYGSAAGLAV 119
Query: 130 HVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEG 189
+++ K S++ A A + V G R V A R Y SH + P F +G
Sbjct: 120 DIYVPETVAGRKFSQIQAYGANVIKVKGSREDVQSAAER----SESFYASHVLRPEFRDG 175
Query: 190 TKTIAFEIYEQI-KLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFE 248
+T+A+EIY Q ++P ++IPV +GT LG++ G + L+E GEI MP++VAVQ E
Sbjct: 176 IRTLAYEIYRQYDRMPRNIYIPVSAGTLLLGLYSGLRHLMESGEIAEMPAIVAVQTEAVS 235
Query: 249 SLCKR--------SKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETLASLHW 300
LC + + +++AD + +P +++M Q I E G C++V +E + + +
Sbjct: 236 PLCAKINGLNYDPDNKLSSIADALVSRKPVLLQKMYQVISE-YGRCMTVSDDEIIEARNR 294
Query: 301 LRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGS 339
L K+G LVE +SA AA+ K + SLL+LTGS
Sbjct: 295 LAKKGFLVEYSSATVYAAFRKKPQEN-----SLLVLTGS 328
>pir||G75080 threonine synthase (EC 4.2.99.2) thrc-2 PAB1677 [similarity] -
Pyrococcus abyssi (strain Orsay)
>gi|5458460|emb|CAB49948.1| (AJ248286) threonine
synthase (thrC-2) [Pyrococcus abyssi]
Length = 394
Score = 173 bits (433), Expect = 4e-42
Identities = 125/354 (35%), Positives = 179/354 (50%), Gaps = 28/354 (7%)
Query: 1 MLVCTKCGRTFDE-KFLLRCTCGGTLLV----KRHYTSFSPRNYLDMRRYIDYLPVDSVF 55
+L C +CGR + E + RC CGG L V + T N + + +Y +LPV +
Sbjct: 2 VLRCIRCGREYPEDEIRYRCECGGLLEVVVDLDKVDTKIFDGNNITLWKYESWLPVKKIV 61
Query: 56 LPKLTPAITPIVKDS--------EDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVV 107
L TP+ + + ++LY K + PTGSFKDRG V ++K E G+ V
Sbjct: 62 --SLNEGGTPLYRLNNLEKILGVKELYAKNEGANPTGSFKDRGMTVGVSKALELGMKRVA 119
Query: 108 IDSSGNAGISLAAYGLSEGIKVHVFL-SYDANKEKISRLSALNAKLHFVDGDRMKVHEEA 166
S+GN SLAAY GI+ +V + S K+++ AK+ + G+
Sbjct: 120 CASTGNTSASLAAYAAKAGIEAYVLVPSGKIALGKLAQAIIYGAKVIPIKGNFDDALRVV 179
Query: 167 IRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI-KLPDYVFIPVGSGTAFLGIWKGFK 225
I S + + Y+ + +NP+ LEG KTIA+EIY+Q+ K+PD V +PVG+ IWKGFK
Sbjct: 180 IEASEELGI-YMLNSINPFRLEGQKTIAYEIYDQLQKVPDNVVLPVGNAGNISAIWKGFK 238
Query: 226 ELIEMGEIESMPSLVAVQAEGFESLCKRSKRK---------NTLADGIAIPEPPRIEEMK 276
EL E G I+ +P ++ +QAEG L K K K TLA I I P E+
Sbjct: 239 ELYEAGVIDKLPRMIGIQAEGASPLAKAWKEKRKFKPEKNPETLATAIRIGNPANWEKAW 298
Query: 277 QAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELID 329
+A++ES G V EE L + L K G+ VE SA +LA K E +D
Sbjct: 299 RAVEESGGMFEIVSDEEILKAQRILASKEGLFVEPASAASLAGLIKLLNEEKVD 352
>gb|AAG20250.1| (AE005100) threonine synthase; ThrC3 [Halobacterium sp. NRC-1]
Length = 363
Score = 172 bits (431), Expect = 6e-42
Identities = 121/358 (33%), Positives = 178/358 (48%), Gaps = 19/358 (5%)
Query: 1 MLVCTKCGRTFD----EKFLLRCTCGGTLLVKRHYTSFSPRNY---LDMRRYIDYLPVDS 53
MLVC CG T++ E + R +R + P + + ++LPV +
Sbjct: 1 MLVCRSCGATYETGPEEPWRCRACEHAVDFAERPRATGDPTAVDPTAGLWAFSEFLPVAA 60
Query: 54 VFLPKLTPAITPIVKDSE-DLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSG 112
L TP+V SE D KLDY+ P+GS+KDRG V + + G++ VV DSSG
Sbjct: 61 DDAVSLGEGWTPLVSASEWDAEFKLDYVCPSGSYKDRGAAVLMTRAAALGVDRVVEDSSG 120
Query: 113 NAGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRD 172
NAG ++A Y GI +++ DA K+ + A A V G R V E + +
Sbjct: 121 NAGAAVAQYAARAGIDAEIYVPADAPAAKLDAMEAAGATTVPVAGGRRAVTEACVSEAVG 180
Query: 173 GNLTYVSHWMNPYFLEGTKTIAFEIYEQ--IKLPDYVFIPVGSGTAFLGIWKGFKELIEM 230
+ Y SH +P F GT T+A+EI Q + PD V +PVG GT LG ++GF+ L
Sbjct: 181 SDAWYASHAWSPSFYAGTATVAYEIAAQRGWRAPDAVVVPVGHGTLLLGAYRGFRALAAG 240
Query: 231 GEIESMPSLVAVQAEGFESL-------CKRSKRKNTLADGIAIPEPPRIEEMKQAIKESS 283
G IESMP L+ VQA G E + N ADGI I P R++++ A+ +
Sbjct: 241 GWIESMPRLLGVQAAGVEPVAAAVNGSASDEDAVNEAADGIQIRSPARLDQVAAAVAATD 300
Query: 284 GFCISVGKEETLASLHWLRKRGILVEGTSAVTLA--AYWKAKELELIDGVSLLILTGS 339
G ++ + T +L L + G+ VE TSAV +A A ++A+ + ++ LTGS
Sbjct: 301 GDVVACDESATTDALASLHEAGLYVEPTSAVAVAGLAAYRARGVVGDSDDVVVALTGS 358
>pir||E71136 threonine synthase (EC 4.2.99.2) PH0857 [similarity] - Pyrococcus
horikoshii >gi|3257268|dbj|BAA29951.1| (AP000003) 394aa
long hypothetical threonine synthase [Pyrococcus
horikoshii]
Length = 394
Score = 169 bits (424), Expect = 4e-41
Identities = 127/364 (34%), Positives = 189/364 (51%), Gaps = 31/364 (8%)
Query: 1 MLVCTKCGRTFDE-KFLLRCTCGGTLLV-----KRHYTSFSPRNYLDMRRYIDYLPVDSV 54
+L C CGR + E + RC CGG L V K + F+ R+ + + +Y +LPV
Sbjct: 2 VLRCVVCGREYPEDEVRYRCDCGGLLEVVIDLDKVDTSIFNGRD-IKLWKYESWLPVKKR 60
Query: 55 FLPKLTPAITPIVKDS--------EDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEV 106
L TP+ + S ++LY K + PTGSFKDRG V ++K E G+++V
Sbjct: 61 V--SLEEGGTPLYRLSNLENELKVKELYAKNEGANPTGSFKDRGMTVGVSKALELGMDKV 118
Query: 107 VIDSSGNAGISLAAYGLSEGIKVHVFL-SYDANKEKISRLSALNAKLHFVDGDRMKVHEE 165
+ S+GN SLAAY GIK +V + S K+++ AK+ + G+
Sbjct: 119 ICASTGNTSASLAAYAAKAGIKAYVLIPSGKIALGKLAQAIIHGAKVIPIKGNFDDALRI 178
Query: 166 AIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI-KLPDYVFIPVGSGTAFLGIWKGF 224
+ SR+ + Y+ + +NP+ LEG KTIA+EIY+Q+ K+PD + +PVG+ IWKGF
Sbjct: 179 VVEASRELGI-YMLNSINPFRLEGQKTIAYEIYDQLGKVPDNIILPVGNAGNISAIWKGF 237
Query: 225 KELIEMGEIESMPSLVAVQAEGFESLCKRSKRK---------NTLADGIAIPEPPRIEEM 275
KE+ E G I+ +P ++ +QAEG L K K K T+A I I P +
Sbjct: 238 KEMYEAGVIDELPRMIGIQAEGASPLVKAWKEKKKFQPEENPETVASAIRIGNPANWIKA 297
Query: 276 KQAIKESSGFCISVGKEETLASLHWLRKR-GILVEGTSAVTLAAYWKAKEL-ELIDGVSL 333
+A++ES G SV EE L + L R G+ VE SA +LA K E E+ S
Sbjct: 298 WKAVEESGGLFESVSDEEILRAQRLLASREGLFVEPASAASLAGLIKLLESGEISRNESY 357
Query: 334 LILT 337
+++T
Sbjct: 358 ILIT 361
>gb|AAK41164.1| Threonine synthase (thrC-2) [Sulfolobus solfataricus]
Length = 396
Score = 161 bits (403), Expect = 1e-38
Identities = 117/357 (32%), Positives = 175/357 (48%), Gaps = 22/357 (6%)
Query: 4 CTKCG--RTFDEKFLLRCTCGGTL---LVKRHYTSFSPRNYLDMRRYIDYLPVDSVFLPK 58
C CG D+ +L CGG L L SFS + RY + + +
Sbjct: 3 CLNCGYETEIDQSQILCPRCGGLLEIILEPPKDFSFSKLRGRGVWRYKELIAGRYKNIVS 62
Query: 59 LTPAITPIVKDS---EDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAG 115
+ TP+++ S ++LY K + L PTGSFKDRG V ++ V+ S+GN
Sbjct: 63 INEGNTPLIRSSNINDNLYFKFEGLNPTGSFKDRGMTVAVSSAVSLNYKTVIAASTGNTA 122
Query: 116 ISLAAYGLSEGIKVHVFLSYD-ANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGN 174
S AAY GIK + L K+++ + + VDG + +R +D
Sbjct: 123 ASAAAYAARAGIKSFIVLPKGKVALGKLAQSILYGSVILEVDGSFDVAMDAVMRLYKDLK 182
Query: 175 LTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIE 234
+ Y + NP+ LEG KTIAFEI E++ +PD V +PVG+ IWKGF EL++ G I
Sbjct: 183 VVYPLNSFNPWRLEGQKTIAFEIAEELGVPDNVIVPVGNAGNIYAIWKGFNELVKTGVIN 242
Query: 235 SMPSLVAVQAEGFESLCKR----------SKRKNTLADGIAIPEPPRIEEMKQAIKESSG 284
++P ++ +QAEG + + +T+A I I +P ++ +AI+ES+G
Sbjct: 243 TIPRMIGIQAEGASPIVTAIIKGKDSPDFIENPDTVATAIRIGKPVNWQKAMKAIRESNG 302
Query: 285 FCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELI--DGVSLLILTG 338
I+V E L + L RK GI E SA LA Y KA +++ D ++LILTG
Sbjct: 303 TAIAVSDSEILDAQKTLARKEGIGAEPASAAALAGYIKAINEKVVDKDEKTVLILTG 359
>sp|Q58860|THRC_METJA PROBABLE THREONINE SYNTHASE >gi|2118306|pir||H64482 threonine
synthase (EC 4.2.99.2) - Methanococcus jannaschii
>gi|1592106|gb|AAB99473.1| (U67587) threonine synthase
(thrC) [Methanococcus jannaschii]
Length = 405
Score = 160 bits (401), Expect = 2e-38
Identities = 119/358 (33%), Positives = 178/358 (49%), Gaps = 33/358 (9%)
Query: 4 CTKCGRTFD-EKFLLRCTCGGTLLVKRHYTSFSPR--------NYLDMRRYIDYLPV-DS 53
C KCG+T+D ++ + C CGG L + Y + + + RY++YLPV D
Sbjct: 5 CIKCGKTYDVDEIIYTCECGGLLEIIYDYEEIKDKVSEEKLRKREIGVWRYLEYLPVKDE 64
Query: 54 VFLPKLTPAITPIVKDS--------EDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINE 105
+ L TP+ + + ++LY+K + PTGSFKDRG V + + E G+
Sbjct: 65 SKIVSLCEGGTPLYRCNNLEKELGIKELYVKNEGANPTGSFKDRGMTVGVTRANELGVEV 124
Query: 106 VVIDSSGNAGISLAAYGLSEGIKVHVFL-SYDANKEKISRLSALNAKLHFVDGDRMKVHE 164
V S+GN SLAAY G K V L K+++ AK+ V G+ +
Sbjct: 125 VGCASTGNTSASLAAYSARSGKKCIVLLPEGKVALGKLAQAMFYGAKVIQVKGNFDDALD 184
Query: 165 EAIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTAFLGIWK 222
+ +++ L Y+ + +NP+ LEG KTIAFEI +Q+ ++PD V +PVG+ IWK
Sbjct: 185 MVKQLAKE-KLIYLLNSINPFRLEGQKTIAFEICDQLNWQVPDRVIVPVGNAGNISAIWK 243
Query: 223 GFKELIEMGEIESMPSLVAVQAEG----FESLCKRS------KRKNTLADGIAIPEPPRI 272
GFKE G I+ +P + +QA+G E+ KR+ K T+A I I P
Sbjct: 244 GFKEFEITGIIDELPKMTGIQADGAKPIVEAFRKRAKDIIPYKNPETIATAIRIGNPVNA 303
Query: 273 EEMKQAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELID 329
+ AI S G+ +V EE + + L RK GI VE SA ++A K E +ID
Sbjct: 304 PKALDAIYSSGGYAEAVTDEEIVEAQKLLARKEGIFVEPASASSIAGLKKLLEEGIID 361
>pir||H72628 probable threonine synthase (EC 4.2.99.2) APE1488 [similarity] -
Aeropyrum pernix (strain K1) >gi|5105172|dbj|BAA80486.1|
(AP000061) 345aa long hypothetical threonine synthase
[Aeropyrum pernix]
Length = 345
Score = 159 bits (397), Expect = 6e-38
Identities = 108/307 (35%), Positives = 161/307 (52%), Gaps = 24/307 (7%)
Query: 50 PVDSVFLPKLTPAI----TPIVKDSEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINE 105
P+++V LP+L P + TP+V+ E +Y KL+YL P+GSFKDRG ++ G +
Sbjct: 38 PLEAVGLPRLPPVLGEGSTPLVEAGEGVYAKLEYLNPSGSFKDRGVGYSLRMASLLGYDC 97
Query: 106 VVIDSSGNAGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEE 165
VV+DSSGN G+S A Y G+K V++ A+ K + + A A+L + EE
Sbjct: 98 VVVDSSGNTGLSTALYSARLGLKARVYVPRGASPGKKALIRATGAELVEAES-----REE 152
Query: 166 AIRF--SRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKG 223
A R + +V+H NP F+EG K++ E+ + V PV SGT LGI++G
Sbjct: 153 AARLAEAEAEKCFHVAHPTNPLFIEGVKSLGRELAGEAAGDTDVLAPVSSGTLLLGIYRG 212
Query: 224 FKELIEMGEIESMPSLVAVQAEGFESLCKRSKR-------KNTLADGIAIPEPPRIEEMK 276
+E E G LVAVQ+ SL + L D + + PPR+EEM
Sbjct: 213 LEE--ERGRFR----LVAVQSPAAYSLKGLVPELGWVGGVEGRLLDALLLARPPRLEEMA 266
Query: 277 QAIKESSGFCISVGKEETLASLHWLRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLIL 336
+A++ES G + VG ++ +RG LVE +SA AA+ +E + + G SLL+L
Sbjct: 267 RAVRESGGGVVVVGDGAIPGAVREAVQRGFLVEPSSAAVFAAHEVLREKKWLSGRSLLVL 326
Query: 337 TGSAKNF 343
TGS +
Sbjct: 327 TGSGLKY 333
>pir||E75118 probable threonine synthase (EC 4.2.99.2) thrc-2 PAB1869
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5458173|emb|CAB49662.1| (AJ248285) threonine
synthase (thrC-2) [Pyrococcus abyssi]
Length = 439
Score = 152 bits (381), Expect = 4e-36
Identities = 118/354 (33%), Positives = 176/354 (49%), Gaps = 21/354 (5%)
Query: 4 CTKCGRTFDEKFLLRCTCGGTLLVKRHYTSFSPRNYLDMR----RYIDYLPVDSVFLPKL 59
C KCGR + + C CG L + Y+S R + + R RY + LP + L
Sbjct: 3 CPKCGREYKAEIPPFCICGEELEITYDYSSVDTRKWKNRRPGVWRYKELLPKVKKIV-SL 61
Query: 60 TPAITPIVKD------SEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGN 113
TP++K + D+++K + PTGSF+DR V I+ N ++ S GN
Sbjct: 62 QEGGTPLIKARISEQLNVDVFIKDETRNPTGSFRDRLATVAISYGLPYAKNGFIVASDGN 121
Query: 114 AGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDG 173
A S+AAY + V + +K K+ ++ A A++ E A ++
Sbjct: 122 AAASVAAYSARAEKECFVVIPRKVDKGKLIQMIAFGARIIRYGESVDDAIEYAKELAKLN 181
Query: 174 NLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEI 233
L V+ N LEG KTIAFE++E+I P +V +P GSG+ I+KGFKELIE+G +
Sbjct: 182 GLYNVTPEENIVGLEGQKTIAFELWEEIN-PTHVIVPTGSGSYLYSIYKGFKELIEIGAL 240
Query: 234 ESMPSLVAVQAE-----GFESLCKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCIS 288
E MP L+AVQ + E L + + K T A G+ + EP ++ +AI+ESSG +
Sbjct: 241 EEMPKLIAVQTDRCNPIASEILGIKGECKETKALGLYVREPLMKPKVIRAIRESSGTAVL 300
Query: 289 VGKEETLASLHWLRKRGILVEGTSAVTLAAYWKAKE---LELIDGVSLLILTGS 339
V +EE L GI E +SAV + A K +E D V +L++TGS
Sbjct: 301 VSEEEIEKGERLLANEGIFAELSSAVVMPALIKLVNDGFIEKGDRV-VLVVTGS 353
>pir||H71013 probable threonine synthase (EC 4.2.99.2) PH1406 [similarity] -
Pyrococcus horikoshii >gi|3257829|dbj|BAA30512.1|
(AP000006) 440aa long hypothetical threonine synthase
[Pyrococcus horikoshii]
Length = 440
Score = 149 bits (373), Expect = 4e-35
Identities = 116/357 (32%), Positives = 176/357 (48%), Gaps = 27/357 (7%)
Query: 4 CTKCGRTFDEKFLLRCTCGGTLLVKRHYTSFSPRNYLDMR----RYIDYLPVDSVFLPKL 59
C +CGR + C CG L + Y+S R + RY + LP + L
Sbjct: 3 CPRCGREYISSIPPFCICGEELEITYDYSSVDVRKWKRRNPGVWRYKELLPEVKKIIT-L 61
Query: 60 TPAITPIVKD------SEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGN 113
TP++K + D+Y+K + PTGSF+DR V I+ N ++ S GN
Sbjct: 62 QEGGTPLIKARISEKINVDVYIKDETRNPTGSFRDRLATVAISYGLPYASNGFIVASDGN 121
Query: 114 AGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRD- 172
A S+AAY + V + +K K+ ++ A A++ GD + +EAI ++R+
Sbjct: 122 AAASVAAYSARAEKECFVVVPRKVDKGKLIQMIAFGARI-IRYGDSV---DEAIEYAREL 177
Query: 173 ---GNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIE 229
L V+ N LEG KTIAFE++E+I P +V +P GSG+ I+KGFKELI+
Sbjct: 178 SKLNGLYNVTPEDNIIGLEGQKTIAFELWEEIN-PTHVIVPTGSGSYIYSIYKGFKELIK 236
Query: 230 MGEIESMPSLVAVQAE-----GFESLCKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSG 284
+G +E MP L+AVQ E E L + + K T A G+ + P + +AIKES G
Sbjct: 237 IGVLEKMPRLIAVQTERCNPIAAEILGLKKECKETKALGLYVKNPVMKSRVIRAIKESGG 296
Query: 285 FCISVGKEETLASLHWLRKRGILVEGTSAVTLAAYWKAKELELID--GVSLLILTGS 339
+ V + + + L GI E +SAV + A E +I+ +L++TGS
Sbjct: 297 TAVVVNENDIITGEKLLANEGIFAELSSAVVMPALLSLVEKGIIEKGDKVVLVVTGS 353
>pir||B72455 threonine synthase (EC 4.2.99.2) APE2286 [similarity] - Aeropyrum
pernix (strain K1) >gi|5105987|dbj|BAA81298.1|
(AP000064) 393aa long hypothetical threonine synthase
[Aeropyrum pernix]
Length = 393
Score = 146 bits (366), Expect = 3e-34
Identities = 119/339 (35%), Positives = 165/339 (48%), Gaps = 25/339 (7%)
Query: 21 CGGTLLVKRHYTSFSPRNYLDMRRYIDYLPVDSVFLPKLTPAITPIVKDSE-------DL 73
CGG LL + SPR + RY D LP + + TP+VK ++
Sbjct: 19 CGG-LLEPFYIDGGSPRGR-GVWRYRDLLPRPRRIVT-MGEGSTPLVKLENLSRAMGVEV 75
Query: 74 YLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAGISLAAYGLSEGIKVHVFL 133
Y KL++L PTGSFKDRG V ++ VV S+GN S+AAY G+ + +
Sbjct: 76 YGKLEFLNPTGSFKDRGMTVGVSIASSFSYRLVVAASTGNTAASMAAYARRAGLNPVILI 135
Query: 134 SYDANKE-KISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGTKT 192
K+S+++AL A + V+G +A R + + L Y + +NPY LEG KT
Sbjct: 136 PKGGIASGKLSQIAALGAWVLEVEGS-FDDALDAARAAAEKGLAYSLNSINPYRLEGQKT 194
Query: 193 IAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFESL-- 250
IAFEI E + D+V +PVG+ IWKGFKE +G P +V VQAEG L
Sbjct: 195 IAFEILEDVDRVDHVVVPVGNAGNISAIWKGFKEAGLLGLPSMRPRMVGVQAEGASPLYR 254
Query: 251 --------CKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETL-ASLHWL 301
+R + +T+A I I P + A++ES G ISV E L A+
Sbjct: 255 AWVEKMDSVERVRNPSTIASAIRIGNPVNAAKALAAVRESDGLIISVSDAEILKAAATLA 314
Query: 302 RKRGILVEGTSAVTLAAYWKAKELELIDGVS--LLILTG 338
G+LVE SA +LA K + +I S +LILTG
Sbjct: 315 ENEGMLVEPASAASLAGLIKLRNQGIIASGSSVVLILTG 353
>pir||G69131 threonine synthase (EC 4.2.99.2) - Methanobacterium
thermoautotrophicum >gi|2621303|gb|AAB84759.1|
(AE000812) threonine synthase [Methanobacterium
thermoautotrophicum]
Length = 406
Score = 142 bits (354), Expect = 7e-33
Identities = 116/353 (32%), Positives = 172/353 (47%), Gaps = 29/353 (8%)
Query: 4 CTKCGRTFD-EKFLLRCT-CGGTLLVKRHYTS----FSPRNYLDMRRYIDYLPVDSVFLP 57
C CGR +D E+ + C CG L V+ F R +M RY +++PVD +
Sbjct: 9 CISCGREYDLEEIIYTCRECGSVLEVECDVEVSRDVFRGRRQ-NMWRYREFMPVDPSRIV 67
Query: 58 KLTPAITPIVK----DSE---DLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDS 110
L TP V+ SE +LY+K++ PTGSFKDRG V I K E G++ V S
Sbjct: 68 SLDEGGTPFVRCDTIGSELGIELYVKVEGSNPTGSFKDRGMSVGITKALELGVDTVGCAS 127
Query: 111 SGNAGISLAAYGLSEGIKVHVFL-SYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRF 169
+GN SLAAY G+ V L S K+++ A++ V G+ + E
Sbjct: 128 TGNTSASLAAYAARAGLGCVVLLPSGKVALGKLAQAMFHGARVLSVRGNFDEALEAVTEL 187
Query: 170 SRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTAFLGIWKGFKEL 227
+ G L Y+ + +NP+ LEG K+I FEI + + + PD + +PVG+ IWKG E
Sbjct: 188 ALMGEL-YLLNSVNPFRLEGQKSIGFEIVDDLGWESPDRIILPVGNAGNISAIWKGISEF 246
Query: 228 IEMGEIESMPSLVAVQAEGFESLCKRSKR----------KNTLADGIAIPEPPRIEEMKQ 277
G I+ P + +QAEG + + ++ T+A I I P + +
Sbjct: 247 YRAGFIDERPMMTGIQAEGASPVVEAFRKGRTEIEPVRDPETVATAIRIGAPVSYLKALR 306
Query: 278 AIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELID 329
AI ES G+ SV EE L++ L R+ GI VE SA ++A K + ++D
Sbjct: 307 AIYESDGYAESVTDEEILSAQKLLARREGIGVEPASAASIAGLIKLVDEGVVD 359
>gi|11498914 threonine synthase (thrC-2) [Archaeoglobus fulgidus]
>gi|7436916|pir||C69414 threonine synthase (EC 4.2.99.2)
thrC-2 AF1316 [similarity] - Archaeoglobus fulgidus
>gi|2649262|gb|AAB89930.1| (AE001013) threonine synthase
(thrC-2) [Archaeoglobus fulgidus]
Length = 396
Score = 135 bits (336), Expect = 8e-31
Identities = 112/359 (31%), Positives = 172/359 (47%), Gaps = 40/359 (11%)
Query: 2 LVCTKCGRTF-DEKFLLRCTCGGTLLVKRHYTSFSPRNYLD-----MRRYIDYLPVDSVF 55
L C +CG+ + DE + C CGG L V+ LD + +Y LPV +
Sbjct: 4 LKCIECGKEWGDENYT--CECGGLLEVEIDLDEVEIDFRLDGSNITVWKYRSLLPV-KID 60
Query: 56 LPKLTPAITPIVKDSE--------DLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVV 107
L TP+ + +Y+K + L P+GSFKDRG V + K E G V
Sbjct: 61 PVTLKEGGTPLYRAERLEKEVGVRRVYVKHEGLNPSGSFKDRGMTVGVTKALELGRKAVA 120
Query: 108 IDSSGNAGISLAAYGLSEGIKVHVFLSYDANKEKISRLSAL---NAKLHFVDGDRMKVHE 164
S+GN S+A Y G+K +V L A K + +++ AK+ +DG+ +
Sbjct: 121 CASTGNTSASMAMYAAKAGLKAYVLLP--AGKVALGKVAQALMHGAKVIGIDGN----FD 174
Query: 165 EAIRFSRD---GNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIW 221
+A+R R+ Y+ + +NP+ EG KTIA+EI ++I +PD V +PVG+ I+
Sbjct: 175 DALRIVREVCSREPIYLLNSINPFRPEGQKTIAYEIADEIGVPDRVVLPVGNAGNISAIY 234
Query: 222 KGFKELIEMGEIESMPSLVAVQAEGFESLCKRSK----------RKNTLADGIAIPEPPR 271
KGFKEL E+G +SMP + +QAEG + + K T+A I I P
Sbjct: 235 KGFKELREVGLTDSMPKMTGIQAEGAAPIYRAFKEGKEDITPMENPETIATAIRIGNPVS 294
Query: 272 IEEMKQAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELID 329
++ +AI ++G V E + + +L K GI VE SA ++A K ++D
Sbjct: 295 AKKALRAIYSTNGLAEVVSDSEIIEAQKFLAAKEGIGVEPASAASVAGLRKLAANGMLD 353
>pir||D70354 threonine synthase (EC 4.2.99.2) thrC1 [similarity] - Aquifex
aeolicus >gi|2983225|gb|AAC06822.1| (AE000698) threonine
synthase [Aquifex aeolicus]
Length = 409
Score = 134 bits (335), Expect = 1e-30
Identities = 107/358 (29%), Positives = 167/358 (45%), Gaps = 32/358 (8%)
Query: 2 LVCTKCGRTFDEKFLLRCT-CGGTLLVKRHYTSFSP--------RNYLDMRRYIDYLPVD 52
L C +CGR + + + C C G L V Y + + RY+D LPV+
Sbjct: 7 LKCRECGREYPAEPIHVCEFCFGPLEVVYDYDEIKKNISREKIEKGPKSLWRYVDLLPVE 66
Query: 53 SVFLPKLTPAITPIVKDSE--------DLYLKLDYLQ-PTGSFKDRGTYVTIAKLKEEGI 103
+ + LT TP+ K + +LY+K D + PT SFKDR V ++K KE G
Sbjct: 67 NPTVG-LTAGFTPLKKAEKLGEVLGLKNLYIKDDSVNHPTLSFKDRVVSVALSKAKEFGF 125
Query: 104 NEVVIDSSGNAGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVH 163
+ S+GN S+AA+ G+ VF+ + +KI N + V+G+ V+
Sbjct: 126 DTAACASTGNLANSVAAHSAQAGMNCFVFIPANLETQKIIGSLVFNPTVVAVEGNYDDVN 185
Query: 164 EEAIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTAFLGIW 221
+ D +V+ + PY+ EG+KT+AFE+ EQ+ + PD V P SG+ + IW
Sbjct: 186 RLCSEIANDLGWAFVNINIRPYYAEGSKTLAFEVAEQLGWRAPDVVVAPAASGSLYTKIW 245
Query: 222 KGFKELIEMGEIESMPS-LVAVQAEGFESLCK---------RSKRKNTLADGIAIPEPPR 271
KGF EL ++G I+ + + + QAEG + + + + NT+A IAI P
Sbjct: 246 KGFNELKKVGLIDEVKTRMYGAQAEGCSPIAQAWREGRDFIKPVKPNTIAKSIAIGNPAD 305
Query: 272 IEEMKQAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELI 328
Q +ES+G + EE + + L + GI E T+A K E +I
Sbjct: 306 GIYALQVARESNGAWETATDEEIIEGIKLLAQTEGIFTETAGGTTIAVLKKYVEKGMI 363
>pir||H70338 threonine synthase (EC 4.2.99.2) - Aquifex aeolicus
>gi|2983084|gb|AAC06690.1| (AE000689) threonine synthase
[Aquifex aeolicus]
Length = 352
Score = 130 bits (324), Expect = 2e-29
Identities = 98/298 (32%), Positives = 146/298 (48%), Gaps = 22/298 (7%)
Query: 42 MRRYIDYLPVD-SVFLPKLTPAITPIVKDSE---------DLYLKLDYLQPTGSFKDRGT 91
+++Y YLPVD + + L TP+++ +YLK + L PTGSFKDRG
Sbjct: 8 IKQYKKYLPVDENTPIVTLYEGNTPLIEADNLARAIGFKGKIYLKYEGLNPTGSFKDRGM 67
Query: 92 YVTIAKLKEEGINEVVIDSSGNAGISLAAYGLSEGIKVHVFLSYDANK-EKISRLSALNA 150
+ I+K E G V+ S+GN S AAY G++ +V L A K+S+ A
Sbjct: 68 TLAISKAVEAGKRAVICASTGNTSASAAAYAARAGLRAYVLLPKGAVAIGKLSQAMIYGA 127
Query: 151 KLHFVDGDRMKVHEEAIRFSRDGNLTY---VSHWMNPYFLEGTKTIAFEIYEQI-KLPDY 206
K+ + G ++A+ R + + + +NPY +EG KT AFEI + + + PDY
Sbjct: 128 KVLAIQG----TFDDALNIVRKIGENFPVEIVNSVNPYRIEGQKTAAFEICDTLGEAPDY 183
Query: 207 VFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFESLCKRSKRKN--TLADGI 264
FIPVG+ WKGFK E G+I +P ++ QAEG + K KN T+A I
Sbjct: 184 HFIPVGNAGNITAYWKGFKIYYEEGKITKLPRMMGWQAEGAAPIVKGYPIKNPQTIATAI 243
Query: 265 AIPEPPRIEEMKQAIKESSGFCISVGKEETLASLHWLRK-RGILVEGTSAVTLAAYWK 321
I P + +A +ES G +V E L + + G+ E SA ++A K
Sbjct: 244 KIGNPYSWKSALKAAQESGGKIDAVSDSEILYAYKLIASTEGVFCEPASAASVAGLIK 301
>pir||G72364 threonine synthase (EC 4.2.99.2) TM0546 [similarity] - Thermotoga
maritima (strain MSB8)
>gi|4981060|gb|AAD35631.1|AE001729_11 (AE001729)
threonine synthase [Thermotoga maritima]
Length = 348
Score = 130 bits (324), Expect = 2e-29
Identities = 101/309 (32%), Positives = 148/309 (47%), Gaps = 14/309 (4%)
Query: 42 MRRYIDYLPVDS----VFLPKLTPAITPIVKDSEDL----YLKLDYLQPTGSFKDRGTYV 93
+ +Y +LPV + L + + P+V S +L Y+K + PTGSFKDRG V
Sbjct: 6 LEKYRRFLPVTDKTPMLSLNEGNTPLIPLVNMSRELGINIYVKYEGSNPTGSFKDRGMVV 65
Query: 94 TIAKLKEEGINEVVIDSSGNAGISLAAYGLSEGIKVHVFL-SYDANKEKISRLSALNAKL 152
+AK EEG ++ S+GN S AAY GIK V + K+++ A +
Sbjct: 66 AVAKALEEGSKAIMCASTGNTSASAAAYAARAGIKAIVLIPEGKIALGKLAQAMIYGAVV 125
Query: 153 HFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI-KLPDYVFIPV 211
V G+ K E + +T V+ +NPY LEG KT AFEI +++ PDY FIPV
Sbjct: 126 LQVRGNFDKCLELVKEITSKYPITLVNS-INPYRLEGQKTAAFEIVDELGDAPDYHFIPV 184
Query: 212 GSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFESLCKRSKRKN--TLADGIAIPEP 269
G+ W G+KE + G +P ++ QAEG + + +N T+A I I P
Sbjct: 185 GNAGNISAYWMGYKEYYQHGFSTKLPKMMGFQAEGAAPIVRGHPIENPETVATAIRIGNP 244
Query: 270 PRIEEMKQAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELI 328
E+ +A ES G V EE L + L +K GI E SA ++A K +
Sbjct: 245 ANWEKAVRARDESGGDIDMVSDEEILRAQRLLAQKEGIFCEPASAASIAGLLKKHRQGIF 304
Query: 329 DGVSLLILT 337
G +++ T
Sbjct: 305 RGGEIVVCT 313
>gb|AAG19064.1| (AE005005) threonine synthase; ThrC2 [Halobacterium sp. NRC-1]
Length = 398
Score = 129 bits (322), Expect = 4e-29
Identities = 105/375 (28%), Positives = 171/375 (45%), Gaps = 38/375 (10%)
Query: 2 LVCTKCGRTFDEKFLL-RCT-CGGTL-------LVKRHYTSFSPRNYLDMRRYIDYLPV- 51
L C CG +F RC CGG L + +F R + + RY + LP
Sbjct: 10 LECVDCGESFAAAAATHRCPECGGILDPAYDLENLDVDAETFGARRFDSLWRYAELLPFT 69
Query: 52 --DSVFLPKLTPAITPIVKDSEDL-----YLKLDYLQPTGSFKDRGTYVTIAKLKEEGIN 104
+V + + A+ P +++L Y+K + PTG+F+DRG V + + G +
Sbjct: 70 RGSAVSMDEGATALVPCPGLADELGVGELYIKDEGRNPTGTFRDRGQTVAMTAAAQHGAS 129
Query: 105 EVVIDSSGNAGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVD---GDRMK 161
EV + S+GNAG S AY G+ HVFL + + ++ ++ V GD
Sbjct: 130 EVALASTGNAGQSAGAYAGRAGLDAHVFLPSRSGFTTKAMVNVHGGDMNVVQGRIGDANA 189
Query: 162 VHEEAIRFSRDGNLTY-VSHWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTAFL 218
E+A+ G Y + + PY EG KT+ +E EQ+ + PD+V P G G +
Sbjct: 190 AFEDAM--DEHGEAWYSLQAFATPYRHEGKKTLLYETVEQLDWETPDHVVYPTGDGGGLV 247
Query: 219 GIWKGFKELIEMGEIESMPSLVAVQAEGFESLCKRSKR----------KNTLADGIAIPE 268
G+WK EL E+G +P++ A QAEG + + + +T+ GI IP+
Sbjct: 248 GMWKAATELRELGITADVPAMYAAQAEGCAPIVRAFQEGRDAHEPWDTPDTICGGIEIPD 307
Query: 269 PPRIEEMKQAIKESSGFCISVGKEETL-ASLHWLRKRGILVEGTSAVTLAAYWKAKELEL 327
P + +A++ES+G ++ EE L A + G + T A A W+ + +
Sbjct: 308 PAGSRLVLEALRESNGGAVAASDEEILEAGTAVASRAGPEMGATCAAAAAGAWELADRDA 367
Query: 328 I--DGVSLLILTGSA 340
D +++ TG+A
Sbjct: 368 FGEDDTVVVVSTGTA 382
>sp|P74193|THRC_SYNY3 THREONINE SYNTHASE >gi|7436917|pir||S75823 threonine synthase (EC
4.2.99.2) 2 - Synechocystis sp. (strain PCC 6803)
>gi|1653368|dbj|BAA18282.1| (D90913) threonine synthase
[Synechocystis sp.]
Length = 382
Score = 119 bits (296), Expect = 4e-26
Identities = 89/285 (31%), Positives = 138/285 (48%), Gaps = 8/285 (2%)
Query: 61 PAITPIVKDSEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAGISLAA 120
PAI + +++K D L PTGSFKDRG + I+K KE G V+ S+GN + AA
Sbjct: 67 PAIAKRIGKDVRVFVKYDGLNPTGSFKDRGMTMAISKAKEAGAKAVICASTGNTSAAAAA 126
Query: 121 YGLSEGIKVHVFL--SYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYV 178
Y G++ V + Y A K+ + A++ +DG+ + S +T V
Sbjct: 127 YARRAGLRAFVIIPDGYVA-LGKLGQALIYGAEVIAIDGNFDDALTTVRQLSEHYPVTLV 185
Query: 179 SHWMNPYFLEGTKTIAFEIYEQI-KLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMP 237
+ +NPY LEG KT AFEI + + + PD++ IPVG+ W GF + E+G+ + +P
Sbjct: 186 NS-VNPYRLEGQKTAAFEIVDVLGQAPDWLCIPVGNAGNITAYWMGFCQYKELGKGDRLP 244
Query: 238 SLVAVQAEGFESLCKRS--KRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETL 295
++ QA G + TLA I I P ++ A +ES+G V E L
Sbjct: 245 RMMGFQAAGSAPFIQGQPISHPETLATAIRIGNPANWDKAWAASRESNGEFHPVTDAEIL 304
Query: 296 ASLHWL-RKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGS 339
+ L + G+ E SA ++A K K+ + +LTG+
Sbjct: 305 EAYRILAAEEGVFCEPASAASVAGLLKQKDQVPAGATVVCVLTGN 349
>pir||S77200 threonine synthase (EC 4.2.99.2) 1 - Synechocystis sp. (strain PCC
6803) >gi|1652839|dbj|BAA17758.1| (D90908) threonine
synthase [Synechocystis sp.]
Length = 433
Score = 117 bits (291), Expect = 2e-25
Identities = 98/339 (28%), Positives = 155/339 (44%), Gaps = 25/339 (7%)
Query: 26 LVKRHYTSFS-PRNYLDMRRYIDYLPVDSVFLPKLTPAITPIVKDS--------EDLYLK 76
L++RH T + + RY +LPV + + +TP+VK ++LY+K
Sbjct: 50 LIRRHVTRETIEAGPNSIWRYRAFLPVTGKDVIDVGTGMTPLVKSHRLARRLGLKNLYIK 109
Query: 77 LDYLQ-PTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAGISLAAYGLSEGIKVHVFLSY 135
D + PT SFKDR V + + +E G V S+GN S AA G+ VF+
Sbjct: 110 NDAVNMPTLSFKDRVVSVALTRARELGFTTVSCASTGNLANSTAAIAAHAGLDCCVFIPA 169
Query: 136 DANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGTKTIAF 195
D K+ N L V G+ +V+ +V+ + PY+ EG+KT+ F
Sbjct: 170 DLEAGKVLGTLIYNPTLMAVKGNYDQVNRLCCEVGNSYGWGFVNINLRPYYSEGSKTLGF 229
Query: 196 EIYEQI--KLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMP-SLVAVQAEGFESLCK 252
E+ EQ+ KLPD++ P+ SG+ F I KGF+E I++G ++ P QAEG +
Sbjct: 230 EVAEQLGWKLPDHIVAPLASGSLFTKIHKGFQEFIKVGLVDDKPVRFSGAQAEGCSPIAT 289
Query: 253 ---------RSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETLASLHWLRK 303
+ + NT+A IAI P ++++G SV E + + L +
Sbjct: 290 AFQEGRDFVKPVKPNTIAKSIAIGNPADGVYALDIARKTNGNIESVNDAEIIEGIKLLAE 349
Query: 304 -RGILVEGTSAVTLAAYWKAKELELID--GVSLLILTGS 339
GI E T+A K E ID +++ +TG+
Sbjct: 350 TEGIFTETAGGTTVAVLKKLVEAGKIDPEETTVVYITGN 388
>sp|P04990|THRC_BACSU THREONINE SYNTHASE >gi|80429|pir||A25364 threonine synthase (EC
4.2.99.2) thrC - Bacillus subtilis
>gi|40211|emb|CAA28270.1| (X04603) threonine synthase
[Bacillus subtilis] >gi|2635722|emb|CAB15215.1| (Z99120)
threonine synthase [Bacillus subtilis]
Length = 352
Score = 117 bits (290), Expect = 2e-25
Identities = 97/316 (30%), Positives = 162/316 (50%), Gaps = 23/316 (7%)
Query: 42 MRRYIDYLPV-DSVFLPKLTPAITPIV---KDSE----DLYLKLDYLQPTGSFKDRGTYV 93
+ +Y ++LPV D L TP++ K SE +L++K + + PTGSFKDRG +
Sbjct: 6 IHQYKEFLPVTDQTPALTLHEGNTPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVM 65
Query: 94 TIAKLKEEGINEVVIDSSGNAGISLAAYGLSEGIKVHVFL-SYDANKEKISRLSALNAKL 152
+AK KEEG + ++ S+GN + AAY +K V + + K+++ A++
Sbjct: 66 AVAKAKEEGNDTIMCASTGNTSAAAAAYAARANMKCIVIIPNGKIAFGKLAQAVMYGAEI 125
Query: 153 HFVDG---DRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI-KLPDYVF 208
+DG D +K+ +R + + + + +NPY +EG KT AFE+ EQ+ + PD +
Sbjct: 126 IAIDGNFDDALKI----VRSICEKSPIALVNSVNPYRIEGQKTAAFEVCEQLGEAPDVLA 181
Query: 209 IPVGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFESLCKRSKRKN--TLADGIAI 266
IPVG+ WKGFKE E +P + +AEG ++ + +N T+A I I
Sbjct: 182 IPVGNAGNITAYWKGFKEYHEKNG-TGLPKMRGFEAEGAAAIVRNEVIENPETIATAIRI 240
Query: 267 PEPPRIEEMKQAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWK-AKE 324
P ++ +A +ES+G V +E L + + R G+ E S ++A K K
Sbjct: 241 GNPASWDKAVKAAEESNGKIDEVTDDEILHAYQLIARVEGVFAEPGSCASIAGVLKQVKS 300
Query: 325 LELIDGVSLL-ILTGS 339
E+ G ++ +LTG+
Sbjct: 301 GEIPKGSKVVAVLTGN 316
>gb|AAG20514.1| (AE005123) threonine synthase; ThrC1 [Halobacterium sp. NRC-1]
Length = 415
Score = 117 bits (290), Expect = 2e-25
Identities = 103/353 (29%), Positives = 162/353 (45%), Gaps = 33/353 (9%)
Query: 2 LVCTKCGRTFDE--KFLLRCT-CGGTLLVK-RHYTSFSPRNYLDMRRYIDYLPVDSVFLP 57
L C +CG T + RC C G L + Y F + + RY D LPVD+
Sbjct: 20 LACVECGGTLAPFADVVYRCPECSGLLEARYADYPGFEAFSGRGVWRYADALPVDAGV-- 77
Query: 58 KLTPAITPIVKDSE--------DLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVID 109
+ TP+ + + D+ +K + + PTGSFKDRG V + + G++ +
Sbjct: 78 SVQEGDTPLYEAPDVAAAAGVADVRVKHEGMNPTGSFKDRGMTVGVRVAERLGVDRLACA 137
Query: 110 SSGNAGISLAAYGLSEGIKVHVFL-SYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIR 168
S+GN +LAAYG V V L + KI++ + A++ VDG+ +
Sbjct: 138 STGNTSAALAAYGGRADTPVLVLLPAGKVAAGKIAQAALHGARICEVDGNFDDCLDVVAE 197
Query: 169 FSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQIKL-----PDYVFIPVGSGTAFLGIWKG 223
+ G Y+ + +NP+ LEG KTIAFEI EQ + PD + +PVG+ ++K
Sbjct: 198 LAARGE-AYLLNSLNPFRLEGQKTIAFEILEQSRTATGEWPDRIVLPVGNAGNTAALYKA 256
Query: 224 FKELIEMGEI--ESMPSLVAVQAEGFESLCK-------RSKR---KNTLADGIAIPEPPR 271
F+EL+ G + + MP+L VQA G + + R++R T A I I P
Sbjct: 257 FRELVAAGAMTDDEMPALTGVQAAGAAPMVEAVEAGRGRTERWTDVETRATAIRIGNPVN 316
Query: 272 IEEMKQAIKESSGFCISVGKEETLASLHWLRKRGILVEGTSAVTLAAYWKAKE 324
+ + E+ G ++V + + L GI VE SA ++A +E
Sbjct: 317 APKALPGVYETGGTAVAVSDDRITDAQRMLAGDGIGVEPASAASVAGLLALRE 369
>sp|Q10610|THRC_MYCTU PROBABLE THREONINE SYNTHASE >gi|7436919|pir||C70773 threonine
synthase (EC 4.2.99.2) thrC [similarity] - Mycobacterium
tuberculosis (strain H37RV) >gi|1322419|emb|CAA97760.1|
(Z73419) thrC [Mycobacterium tuberculosis]
Length = 360
Score = 116 bits (288), Expect = 4e-25
Identities = 89/291 (30%), Positives = 137/291 (46%), Gaps = 13/291 (4%)
Query: 45 YIDYLPVDSVFLP-KLTPAITPIVKDSE-------DLYLKLDYLQPTGSFKDRGTYVTIA 96
Y D LPV + P L TP++ + ++LK++ L PTGSFKDRG + +
Sbjct: 19 YRDRLPVGDDWTPVTLLEGGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVT 78
Query: 97 KLKEEGINEVVIDSSGNAGISLAAYGLSEGIKVHVFLSY-DANKEKISRLSALNAKLHFV 155
G V+ S+GN S AAY GI V + K+++ AK+ +
Sbjct: 79 DALAHGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQI 138
Query: 156 DGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI-KLPDYVFIPVGSG 214
DG+ E A + + D + + +NP +EG KT AFEI + + PD +PVG+
Sbjct: 139 DGNFDDCLELARKMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNA 198
Query: 215 TAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFESLC--KRSKRKNTLADGIAIPEPPRI 272
WKG+ E ++G I+ +P ++ QA G L + T+A I I P
Sbjct: 199 GNITAYWKGYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASW 258
Query: 273 EEMKQAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKA 322
+A ++S G ++ EE LA+ H + R G+ VE SA ++A KA
Sbjct: 259 TSAVEAQQQSKGRFLAASDEEILAAYHLVARVEGVFVEPASAASIAGLLKA 309
>sp|P09123|THRC_BRELA THREONINE SYNTHASE >gi|68321|pir||DWFKTG threonine synthase (EC
4.2.99.2) - Corynebacterium glutamicum
>gi|541381|pir||S41448 threonine synthase (EC 4.2.99.2)
- Bacillus sp >gi|452398|emb|CAA82669.1| (Z29562)
threonine synthase [Bacillus sp.]
Length = 352
Score = 115 bits (286), Expect = 6e-25
Identities = 93/296 (31%), Positives = 143/296 (47%), Gaps = 15/296 (5%)
Query: 42 MRRYIDYLPVDS----VFLPKLTPAITPIVKDSEDL----YLKLDYLQPTGSFKDRGTYV 93
+++Y YLPV+ V L + + P++ S+ L Y K + PTGSFKDRG +
Sbjct: 6 LKQYASYLPVNEKTPDVSLMEGNTPLIPLLNISKQLGVQLYGKYEGANPTGSFKDRGMVM 65
Query: 94 TIAKLKEEGINEVVIDSSGNAGISLAAYGLSEGIK-VHVFLSYDANKEKISRLSALNAKL 152
+AK KEEG ++ S+GN S AAY G+K + V K+++ A A++
Sbjct: 66 AVAKAKEEGSEAIICASTGNTSASAAAYAARLGMKCIIVIPEGKIAHGKLAQAVAYGAEI 125
Query: 153 HFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQIK-LPDYVFIPV 211
++G+ + + + +T V+ +NPY +EG KT AFEI +Q++ PD + IPV
Sbjct: 126 ISIEGNFDDALKAVRNIAAEEPITLVNS-VNPYRIEGQKTAAFEICDQLQNAPDVLAIPV 184
Query: 212 GSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFESLCKRS--KRKNTLADGIAIPEP 269
G+ WKGF E E + P + +AEG ++ K + T+A I I P
Sbjct: 185 GNAGNITAYWKGFCE-YEKEKGYKKPRIHGFEAEGAAAIVKGHVIEEPETIATAIRIGNP 243
Query: 270 PRIEEMKQAIKESSGFCISVGKEETLASLHWLRK-RGILVEGTSAVTLAAYWKAKE 324
+A ++S G V EE L + L K G+ E S +LA K E
Sbjct: 244 ASWSYAVEAAEQSHGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVIKHVE 299
>dbj|BAB07140.1| (AP001518) threonine synthase [Bacillus halodurans]
Length = 354
Score = 113 bits (281), Expect = 2e-24
Identities = 91/294 (30%), Positives = 143/294 (47%), Gaps = 17/294 (5%)
Query: 42 MRRYIDYLPV-DSVFLPKLTPAITPIVKDSEDL--------YLKLDYLQPTGSFKDRGTY 92
++ Y ++LPV + L L TP++ E+L Y+K + PTGSFKDRG
Sbjct: 8 LQEYKEFLPVTEETPLLTLGEGNTPLIP-LENLSKEWGVKAYVKYEGANPTGSFKDRGMV 66
Query: 93 VTIAKLKEEGINEVVIDSSGNAGISLAAYGLSEGIK-VHVFLSYDANKEKISRLSALNAK 151
+ +AK KEEG ++ S+GN + AAYG G++ + V K+++ A+
Sbjct: 67 MAVAKAKEEGSRTIICASTGNTSAAAAAYGARAGLRCIVVIPEGKIALGKLAQAVMYGAE 126
Query: 152 LHFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI-KLPDYVFIP 210
+ + G+ + S +T V+ +NPY +EG KT AFEI + + + PD + IP
Sbjct: 127 VLEIKGNFDHALDIVRSISEKEPITLVNS-VNPYRIEGQKTSAFEICDALGQAPDVLAIP 185
Query: 211 VGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFESLCKRS--KRKNTLADGIAIPE 268
VG+ WKGFKE E + +P + +AEG ++ + + T+A I I
Sbjct: 186 VGNAGNITAYWKGFKEYHEK-KGTGLPQMRGFEAEGAAAIVRNQVIEEPETIATAIRIGN 244
Query: 269 PPRIEEMKQAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWK 321
P +A ES+G V EE LA+ L +K G+ E S ++A K
Sbjct: 245 PASWTYAVEAAAESNGKIDEVTDEEILAAYQLLAQKEGVFAEPASCASIAGLRK 298
>emb|CAB93053.1| (AL357432) putative threonine synthase [Streptomyces coelicolor
A3(2)]
Length = 428
Score = 113 bits (280), Expect = 3e-24
Identities = 98/364 (26%), Positives = 157/364 (42%), Gaps = 36/364 (9%)
Query: 2 LVCTKCGRTFDEKFLLRCT-CGGTLLVKRHYTSFSPRNY--------LDMRRYIDYLPV- 51
L C +CG + C C G L + ++ + ++ RY LPV
Sbjct: 23 LSCRECGHRVPLGPVFACEECFGPLEIAYDFSDYDAEELRKRIEAGPANIWRYAPLLPVP 82
Query: 52 -DSVFLPKLTPAITPIVKDSE---------DLYLKLDYLQPTGSFKDRGTYVTIAKLKEE 101
D P + P T +V+ LY+K D PT SFKDR I +
Sbjct: 83 ADVATKPNINPGWTKLVQADNLARELGVTGGLYVKDDSGNPTHSFKDRVVAQAIEAARAF 142
Query: 102 GINEVVIDSSGNAGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMK 161
G + S+GN ++ A G + VF+ +D + K+ + +L ++G+
Sbjct: 143 GFTTLSCSSTGNLAGAVGAAAARAGFRSCVFIPHDLEQGKVVMAAVYGGELVGIEGNYDD 202
Query: 162 VHE---EAIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTA 216
V+ E I +V+ + PY+ EG+KT+A+EI EQ+ +LPD + +P+ SG+
Sbjct: 203 VNRFCSELIGDPAGEGWGFVNVNLRPYYAEGSKTLAYEICEQLGWRLPDQIVVPIASGSQ 262
Query: 217 FLGIWKGFKELIEMGEIESMP-SLVAVQAEGFESLCK---------RSKRKNTLADGIAI 266
I KG KELIE+G +E P + QAEG + R ++ NT+A +AI
Sbjct: 263 LTKIDKGLKELIELGLVEDRPYKIFGAQAEGCSPVSTAYKAGHDVVRPQKPNTIAKSLAI 322
Query: 267 PEPPRIEEMKQAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKEL 325
P + + + G V E+ + ++ L R GI E VT+ K E
Sbjct: 323 GNPADGPYVLDIARRTGGAVEDVTDEQVVDAIKLLARTEGIFAETAGGVTVGVTRKLIEN 382
Query: 326 ELID 329
++D
Sbjct: 383 GVLD 386
>gi|11498161 threonine synthase (thrC-1) [Archaeoglobus fulgidus]
>gi|7436927|pir||G69318 threonine synthase (EC 4.2.99.2)
thrC-1 AF0551 [similarity] - Archaeoglobus fulgidus
>gi|2650068|gb|AAB90683.1| (AE001066) threonine synthase
(thrC-1) [Archaeoglobus fulgidus]
Length = 404
Score = 112 bits (277), Expect = 7e-24
Identities = 86/272 (31%), Positives = 133/272 (48%), Gaps = 13/272 (4%)
Query: 71 EDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSGNAGISLAAYGLSEGIKVH 130
++LYL D PT SFKDR V + K E G++ V S+GN SLAA+ G+K
Sbjct: 91 KNLYLLDDSTNPTYSFKDRVVSVAVTKALEFGMDVVGCASTGNLAGSLAAHAAKAGLKAF 150
Query: 131 VFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFS-RDGNLTYVSHWMNPYFLEG 189
+F+ K KI + A + V+G + A + ++ N +V+ + PY++EG
Sbjct: 151 IFVPAGIEKNKIVQALVHGATVVEVNGTYDDANRLAAEIAEKNRNWGFVNINLRPYYVEG 210
Query: 190 TKTIAFEIYEQI--KLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMP-SLVAVQAEG 246
+KT+AFE E++ + P V +PV SG I++GFKEL +G I+S + A Q EG
Sbjct: 211 SKTLAFEAAERLGWEAPSQVVVPVASGALLYSIYRGFKELETVGLIDSAEVAFNAAQPEG 270
Query: 247 FESLCKRSKRK--------NTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETLASL 298
F +R+ +T+ +AI P K+ ++ S G+ E + ++
Sbjct: 271 FPVARAVKERRQVEPIERFSTIVHSLAIGNPADGIFAKEVVERSGGYAEDPSDAEVIEAV 330
Query: 299 HWL-RKRGILVEGTSAVTLAAYWKAKELELID 329
L R GI E VT+AA + E ID
Sbjct: 331 KLLARTEGIFTELAGGVTVAALIRLVEDGRID 362
>sp|P45837|THRC_MYCLE PROBABLE THREONINE SYNTHASE >gi|7436934|pir||T09991 threonine
synthase (EC 4.2.99.2) - Mycobacterium leprae
>gi|699329|gb|AAA63090.1| (U15186) threonine synthase
[Mycobacterium leprae]
Length = 360
Score = 110 bits (272), Expect = 3e-23
Identities = 89/291 (30%), Positives = 137/291 (46%), Gaps = 13/291 (4%)
Query: 45 YIDYLPVDSVFLP-KLTPAITPIV---KDSED----LYLKLDYLQPTGSFKDRGTYVTIA 96
Y D LPV + P L TP++ + SE ++LK++ L PTGSFKDRG + +
Sbjct: 19 YRDRLPVGDDWTPVTLLEGGTPLIAAPRLSEQTGCTIHLKVEGLNPTGSFKDRGMTMAVT 78
Query: 97 KLKEEGINEVVIDSSGNAGISLAAYGLSEGIKVHVFLSY-DANKEKISRLSALNAKLHFV 155
G V+ S+GN S AAY GI V + K+++ AK+ +
Sbjct: 79 DALARGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQI 138
Query: 156 DGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVF-IPVGSG 214
DG+ E A + + D + + + +NP +EG KT FEI + + +V +PVG+
Sbjct: 139 DGNFDDCLELARKMAADFPMISLVNSVNPVRIEGQKTAVFEIVDALGTAPHVHALPVGNA 198
Query: 215 TAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFESLC--KRSKRKNTLADGIAIPEPPRI 272
WKG+ E G I+ +P ++ QA G L + T+A I I P
Sbjct: 199 GNITAYWKGYTEYHADGLIDRLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASW 258
Query: 273 EEMKQAIKESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKA 322
+A ++S G ++ EE LA+ H + R G+ VE SA ++A KA
Sbjct: 259 TSAVEAQQQSKGRFLAATDEEILAAYHLVARAEGVFVEPASAASIAGLLKA 309
>gb|AAF54364.1| (AE003682) CG8129 gene product [alt 1] [Drosophila melanogaster]
Length = 469
Score = 103 bits (254), Expect = 3e-21
Identities = 92/286 (32%), Positives = 133/286 (46%), Gaps = 41/286 (14%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSS-GNAGISLAAYGLSEGIKVH 130
+LYLK D+LQ TGSFK+RG + L EE VI +S GN +L +G I V
Sbjct: 92 ELYLKKDFLQYTGSFKERGARYALLSLTEEQKRTGVISASLGNHAQALCYHGWKLNIPVT 151
Query: 131 VFLSYDANKEKISRLSALNAKLHFVDGDRM-KVHEEAIRFSRDGNLTYVSHWMNPYFLEG 189
V + A KI + A++ VDG+ M + A+R SR+ L YV+ + +P+ + G
Sbjct: 152 VVMPKAAPIMKIQKCRNYKARV-IVDGNDMGEAKSLAMRMSREEGLLYVNGYDHPHIMAG 210
Query: 190 TKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFES 249
TI EI EQ+ PD V +PVG G GI K L ++ V++E S
Sbjct: 211 QGTIGLEILEQVPEPDAVVVPVGGGGLIAGIATAVKAL------SPKTKIIGVESEKCAS 264
Query: 250 LCKRSKR--------KNTLADGIAIPE---------PPRIEEMKQAIKESSGFCISVGKE 292
+ + KNTLADG+A+P+ P I+ M V KE
Sbjct: 265 FTRAMENDGPIHTPIKNTLADGLAVPKVGYNAYATAMPLIDRM------------VVVKE 312
Query: 293 E--TLASLHWLRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLIL 336
E +A L + + +VEG LAA A L+ + G +++L
Sbjct: 313 EWIAVAILRLVEEEKCVVEGAGGAGLAAI-LAGHLDELKGKKVVVL 357
>gb|AAF59508.1| (AC024805) contains similarity to SW:THD2_ECOLI [Caenorhabditis
elegans]
Length = 368
Score = 101 bits (249), Expect = 1e-20
Identities = 77/276 (27%), Positives = 127/276 (45%), Gaps = 16/276 (5%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINE-VVIDSSGNAGISLAAYGLSEGIKVH 130
++YLK++ Q TGSFK+RG + L EE V S+GN ++L+ +G G++V+
Sbjct: 76 NIYLKMEVNQDTGSFKERGARYALQNLPEEKKKAGVYAASAGNHALALSLHGKQLGVEVN 135
Query: 131 VFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGT 190
V + A KI+R L A + D + E A+R + D N TY++ + + L G
Sbjct: 136 VVMPKIAPLMKINRCQDLGANILVQGEDIAESREIALRMAHDSNGTYINGYDHYDILAGA 195
Query: 191 KTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFESL 250
T EI EQI++PD + +PVG G G+ K L E+ + V +E +++
Sbjct: 196 GTTGIEILEQIQMPDAILVPVGGGGLVAGVATAVKALSPTTEV------IGVVSETCQAI 249
Query: 251 CKR--------SKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETLASLHWLR 302
K + + TLADG+A+P + I + + +A L +
Sbjct: 250 VKSLQAGHPVYTPTRPTLADGLAVPN-AGVNAFASMIGKVDRVISVPENDIAVAILRLIE 308
Query: 303 KRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTG 338
++ EG A+ + A K L + IL+G
Sbjct: 309 NEKVVCEGAGAIGIGAILSGKLNHLKGKTVVSILSG 344
>pir||D72386 threonine dehydratase (EC 4.2.1.16) TM0356 [similarity] -
Thermotoga maritima (strain MSB8)
>gi|4980859|gb|AAD35443.1|AE001716_6 (AE001716)
threonine dehydratase catabolic [Thermotoga maritima]
Length = 401
Score = 98.7 bits (242), Expect = 9e-20
Identities = 82/256 (32%), Positives = 127/256 (49%), Gaps = 16/256 (6%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINE-VVIDSSGNAGISLAAYGLSEGIKVH 130
++YLK++ LQ TGSFK RG Y IA L EE VV S+GN +A GI
Sbjct: 36 EIYLKMENLQKTGSFKIRGAYNKIAHLSEEERKRGVVAASAGNHAQGVALAAQIFGIPAT 95
Query: 131 VFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGT 190
+ + A KI++ L A++ + +E A+R +V + +P+ + G
Sbjct: 96 IVMPRYAPLSKITKTRNLGAQVILEGNIFDEAYEAALRIQEKTGAVFVHPFNDPHVIAGQ 155
Query: 191 KTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFK----ELIEMG-EIESMPSLVAVQAE 245
TI EI E + + V +PVG G G+ K E+ +G + E+MPS++A
Sbjct: 156 GTIGLEIMEDLPDVEVVVVPVGGGGLISGVSVAIKSMNPEVKVIGVQTENMPSMIASLRR 215
Query: 246 GFESLCKRSKRKNTLADGIAIPEPPRI--EEMKQAIKESSGFCISVGKEETL-ASLHWLR 302
G +R + K TLADGIA+ +P + E +K+ + E ++V +EE A L L
Sbjct: 216 G---RAERVEGKPTLADGIAVKKPGDLTFELVKKYVDE----MVAVNEEEIADAILFLLE 268
Query: 303 KRGILVEGTSAVTLAA 318
+ ++ EG AV +AA
Sbjct: 269 QAKVVAEGAGAVGVAA 284
>pir||T23166 hypothetical protein K01C8.1 - Caenorhabditis elegans
>gi|3878113|emb|CAA88854.1| (Z49068) contains similarity
to Pfam domain: PF00291 (Pyridoxal-phosphate dependent
enzyme), Score=292.1, E-value=2.3e-84, N=1; PF01842 (ACT
domain), Score=38.9, E-value=3.8e-08, N=1~cDNA EST
EMBL:M89183 comes from this gene~cDNA EST yk195g4.5
comes fr>
Length = 512
Score = 94.8 bits (232), Expect = 1e-18
Identities = 91/306 (29%), Positives = 142/306 (45%), Gaps = 36/306 (11%)
Query: 60 TPAITPIVKDSE---DLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINE-VVIDSSGNAG 115
TP + + S+ DLY K +YLQ TGSFK+RG ++K+ E+ V+ S+GN
Sbjct: 118 TPCVRSLQLSSKCEMDLYFKKEYLQVTGSFKERGARYALSKMAEQFKKAGVIAASAGNHA 177
Query: 116 ISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEE-AIRFSRDGN 174
++L+ +G GI V V + A KI +L A + + G+ + V ++ A+R +++ +
Sbjct: 178 LALSYHGQQMGIPVTVVMPVIAPLMKIQFCRSLGATV-ILKGESIAVAKDFALRHAKENH 236
Query: 175 LTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKEL------- 227
L Y++ + L G TI EI +Q+ D + +PVG G GI K L
Sbjct: 237 LKYINGYDAIDILAGQGTIGLEILDQVPDVDTILVPVGGGGLIAGIATAVKTLKPDVHIY 296
Query: 228 -----------IEMGEIESMPSLVAVQAEGFESLCKRSKRKNTLADGIAIPE--PPRIEE 274
+ E E+ PS G S+ K +LADG+A+P +E
Sbjct: 297 VSSFLIIANFKVTGIESETCPSFTEAYEAGH---IITSQAKASLADGLAVPTVGGNSLET 353
Query: 275 MKQAIKESSGFCISVGKEETLA--SLHWLRKRGILVEGTSAVTLAAYWKAKELELIDGVS 332
K + + + KEE++A L L +VEG AV LAA + K EL
Sbjct: 354 AKGLVDK-----VITVKEESIALSILRLLEVEKAVVEGGGAVGLAAILEGKVPELKGKKV 408
Query: 333 LLILTG 338
+ IL+G
Sbjct: 409 VSILSG 414
>gb|AAD55628.1|AC008017_1 (AC008017) Putative threonine synthase [Arabidopsis thaliana]
Length = 516
Score = 88.5 bits (216), Expect = 1e-16
Identities = 82/294 (27%), Positives = 133/294 (44%), Gaps = 32/294 (10%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLKE-EGINEVVID----SSGNAGISLAAYGLSEG 126
DL++K + TGSFKD G V ++++ +N+ VI S+G+ +L+AY S G
Sbjct: 179 DLWVKHCGISHTGSFKDLGMSVLVSQVNRLRKMNKPVIGVGCASTGDTSAALSAYCASAG 238
Query: 127 IKVHVFLSYDANKEKISRLSALNAKLHFV-------DGDRMKVHEEAIRFSRDGNLTYVS 179
I VFL A+K +++L A FV DG + E Y++
Sbjct: 239 IPSIVFLP--ADKISMAQLVQPIANGAFVLSIDTDFDGCMHLIREVTAELP-----IYLA 291
Query: 180 HWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMP 237
+ +N LEG KT A EI +Q ++PD+V +P G+ +KGF E+G ++ +P
Sbjct: 292 NSLNSLRLEGQKTAAIEILQQFNWQVPDWVIVPGGNLGNIYAFYKGFHMCKELGLVDRIP 351
Query: 238 SLVAVQA-----------EGFESLCKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFC 286
LV QA GF+ K T A I I +P I+ A+K+S+G
Sbjct: 352 RLVCAQAANANPLYLHYKSGFKEDFNPLKANTTFASAIQIGDPVSIDRAVYALKKSNGIV 411
Query: 287 ISVGKEETLASLHWLRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGSA 340
+EE + + G+ + + V L A K ++ +I ++ +A
Sbjct: 412 EEATEEELMDATALADSTGMFICPHTGVALTALMKLRKSGVIGANDRTVVVSTA 465
>emb|CAC11175.1| (AL445063) threonine synthase related protein [Thermoplasma
acidophilum]
Length = 316
Score = 88.5 bits (216), Expect = 1e-16
Identities = 56/197 (28%), Positives = 95/197 (47%), Gaps = 11/197 (5%)
Query: 61 PAITPIVK--------DSEDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSSG 112
P TP +K +L+LK + TG+ KDR + + G N + + + G
Sbjct: 12 PGRTPTIKAYALGNKLHLNNLFLKFEGANATGTQKDRISEAHVINAMRGGYNGIAVGTCG 71
Query: 113 NAGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRD 172
N G S+A + G+K ++ + + ++ + + A++ + DG + E FS+D
Sbjct: 72 NYGASIAYFAHQYGVKSYIGIPRSYSHDRTDFMQSEQAEILYYDGKYEETVEFIRDFSKD 131
Query: 173 GNLTYVSHWMNPYFLEGTK--TIAFEIYEQI-KLPDYVFIPVGSGTAFLGIWKGFKELIE 229
L S ++ TIAFEIYE + +P YV +PVG+GT GI+ GF+ + +
Sbjct: 132 NGLYDASPGSANSSIDKMMYATIAFEIYEALLTVPSYVIVPVGNGTTLAGIYHGFRRMYD 191
Query: 230 MGEIESMPSLVAVQAEG 246
G I+ +P +V V G
Sbjct: 192 EGVIDHLPRMVGVSTSG 208
>pir||S71362 threonine synthase (EC 4.2.99.2) precursor - Arabidopsis thaliana
(fragment) >gi|1448917|gb|AAB04607.1| (L41666) threonine
synthase [Arabidopsis thaliana]
Length = 525
Score = 86.6 bits (211), Expect = 4e-16
Identities = 79/293 (26%), Positives = 130/293 (43%), Gaps = 31/293 (10%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLK-----EEGINEVVIDSSGNAGISLAAYGLSEG 126
DL++K + TGSFKD G V ++++ + + V S+G+ +L+AY S G
Sbjct: 187 DLWVKHCGISHTGSFKDLGMTVLVSQVNRLRKMKRPVVGVGCASTGDTSAALSAYCASAG 246
Query: 127 IKVHVFLSYDANKEKISRLSALNAKLHFV-------DGDRMKVHEEAIRFSRDGNLTYVS 179
I VFL ANK +++L A FV DG + E Y++
Sbjct: 247 IPSIVFLP--ANKISMAQLVQPIANGAFVLSIDTDFDGCMKLIREITAELP-----IYLA 299
Query: 180 HWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMP 237
+ +N LEG KT A EI +Q ++PD+V +P G+ +KGFK E+G ++ +P
Sbjct: 300 NSLNSLRLEGQKTAAIEILQQFDWQVPDWVIVPGGNLGNIYAFYKGFKMCQELGLVDRIP 359
Query: 238 SLVAVQAEGFESL----------CKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCI 287
+V QA L K T A I I +P I+ A+K+ +G
Sbjct: 360 RMVCAQAANANPLYLHYKSGWKDFKPMTASTTFASAIQIGDPVSIDRAVYALKKCNGIVE 419
Query: 288 SVGKEETLASLHWLRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGSA 340
+EE + ++ G+ + + V L A +K + +I ++ +A
Sbjct: 420 EATEEELMDAMAQADSTGMFICPHTGVALTALFKLRNQGVIAPTDRTVVVSTA 472
>pir||T08545 threonine synthase (EC 4.2.99.2) precursor - Arabidopsis thaliana
>gi|4850369|dbj|BAA77707.1| (AB027151) threonine
synthase [Arabidopsis thaliana]
>gi|4914408|emb|CAB43659.1| (AL050352) threonine
synthase [Arabidopsis thaliana]
>gi|7269883|emb|CAB79742.1| (AL161575) threonine
synthase [Arabidopsis thaliana]
Length = 526
Score = 86.6 bits (211), Expect = 4e-16
Identities = 79/293 (26%), Positives = 130/293 (43%), Gaps = 31/293 (10%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLK-----EEGINEVVIDSSGNAGISLAAYGLSEG 126
DL++K + TGSFKD G V ++++ + + V S+G+ +L+AY S G
Sbjct: 188 DLWVKHCGISHTGSFKDLGMTVLVSQVNRLRKMKRPVVGVGCASTGDTSAALSAYCASAG 247
Query: 127 IKVHVFLSYDANKEKISRLSALNAKLHFV-------DGDRMKVHEEAIRFSRDGNLTYVS 179
I VFL ANK +++L A FV DG + E Y++
Sbjct: 248 IPSIVFLP--ANKISMAQLVQPIANGAFVLSIDTDFDGCMKLIREITAELP-----IYLA 300
Query: 180 HWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMP 237
+ +N LEG KT A EI +Q ++PD+V +P G+ +KGFK E+G ++ +P
Sbjct: 301 NSLNSLRLEGQKTAAIEILQQFDWQVPDWVIVPGGNLGNIYAFYKGFKMCQELGLVDRIP 360
Query: 238 SLVAVQAEGFESL----------CKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCI 287
+V QA L K T A I I +P I+ A+K+ +G
Sbjct: 361 RMVCAQAANANPLYLHYKSGWKDFKPMTASTTFASAIQIGDPVSIDRAVYALKKCNGIVE 420
Query: 288 SVGKEETLASLHWLRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGSA 340
+EE + ++ G+ + + V L A +K + +I ++ +A
Sbjct: 421 EATEEELMDAMAQADSTGMFICPHTGVALTALFKLRNQGVIAPTDRTVVVSTA 473
>gb|AAF74984.1|AF082894_1 (AF082894) threonine synthase [Solanum tuberosum]
Length = 519
Score = 85.0 bits (207), Expect = 1e-15
Identities = 78/293 (26%), Positives = 131/293 (44%), Gaps = 31/293 (10%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLKE-----EGINEVVIDSSGNAGISLAAYGLSEG 126
DL++K + TGSFKD G V ++++ + + V S+G+ +L+AY S G
Sbjct: 181 DLWVKHCGISHTGSFKDLGMTVLVSQVNRLRKMHKPVVGVGCASTGDTSAALSAYCASAG 240
Query: 127 IKVHVFLSYDANKEKISRLSALNAKLHFV-------DGDRMKVHEEAIRFSRDGNLTYVS 179
I VFL ANK +++L A FV DG + E Y++
Sbjct: 241 IPSIVFLP--ANKISMAQLVQPIANGAFVLSIDTDFDGCMQLIREVTAELP-----IYLA 293
Query: 180 HWMNPYFLEGTKTIAFEIYEQI--KLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMP 237
+ +N LEG KT A EI +Q ++P++V +P G+ +KGF+ E+G ++ +P
Sbjct: 294 NSLNSLRLEGQKTAAIEILQQFDWEVPEWVIVPGGNLGNIYAFYKGFQMCKELGLVDRIP 353
Query: 238 SLVAVQAEGFESL----------CKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCI 287
LV QA L K K T A I I +P I+ A+++ +G
Sbjct: 354 RLVCAQAANANPLYLHYKSGWKDFKPVKANTTFASAIQIGDPVSIDRAVFALQQCNGIVE 413
Query: 288 SVGKEETLASLHWLRKRGILVEGTSAVTLAAYWKAKELELIDGVSLLILTGSA 340
+EE + ++ G+ + + V L A +K + +I ++ +A
Sbjct: 414 EATEEELMDAMAQADSTGMFICPHTGVALTALFKLRNSGVIAPTDRTVVVSTA 466
>pir||D81355 threonine dehydratase (EC 4.2.1.16) Cj0828c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968274|emb|CAB73093.1| (AL139076) threonine
dehydratase biosynthetic [Campylobacter jejuni]
Length = 403
Score = 83.5 bits (203), Expect = 3e-15
Identities = 74/257 (28%), Positives = 120/257 (45%), Gaps = 18/257 (7%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLK-EEGINEVVIDSSGNAGISLAAYGLSEGIKVH 130
++YLK + LQ TG++K RG Y IA L E+ + V+ S+GN +A IK
Sbjct: 36 EIYLKNENLQITGAYKIRGAYNKIANLSTEQKQHGVIAASAGNHAQGVAISAKKFSIKAV 95
Query: 131 VFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLEGT 190
+ + K+S AL A++ + + + A ++++ NL+++ + + + + G
Sbjct: 96 IVMPESTPLLKVSATKALGAEVILRGDNFDEAYAFATSYAKENNLSFIHPFEDEFVMAGQ 155
Query: 191 KTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEG---- 246
T+ E+ ++I D + PVG G GI K +I ++ V A+G
Sbjct: 156 GTLMLEMLDEISDLDMIIAPVGGGGLISGISSTAK------QINPNIKIIGVGAKGAPAM 209
Query: 247 FESL----CKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETL-ASLHWL 301
+ES K +K T+ADGIA+ + I I E I V EE A L L
Sbjct: 210 YESFHAKKIKNAKSVRTIADGIAVRDANPIN--FNIILECVDDFIQVDDEEIANAVLFLL 267
Query: 302 RKRGILVEGTSAVTLAA 318
K I+VEG A ++AA
Sbjct: 268 EKHKIIVEGAGAASVAA 284
>gb|AAG20244.1| (AE005099) threonine dehydratase; IluA [Halobacterium sp. NRC-1]
Length = 495
Score = 79.6 bits (193), Expect = 5e-14
Identities = 80/275 (29%), Positives = 125/275 (45%), Gaps = 23/275 (8%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINE-VVIDSSGN--AGISLAAYGLSEGIK 128
D+ KL+ Q TGSFK RG I L + + VV S+GN G++LAA K
Sbjct: 121 DVRPKLECFQRTGSFKIRGATNRIRTLSADQQDAGVVTASAGNHAQGVALAASRSGVDSK 180
Query: 129 VHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLE 188
V + S +K K ++ LH D D + H + + TYV + + Y +
Sbjct: 181 VVMPESAPISKIKATKSYGAEVVLHGADYDDAQAHAHELEAAE--GRTYVHAFDDEYIMA 238
Query: 189 GTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFE 248
G T+ EI D V +P+G G G+ K GE++ + ++ VQAEG
Sbjct: 239 GQGTLGLEIAADCPTVDTVVVPIGGGGLISGVATALK-----GELDDV-RVIGVQAEGAS 292
Query: 249 SLCKRSKR--------KNTLADGIAIPEPPRIEEMKQAIKESSGFCISVGKEETLASLHW 300
++ + + +T+ADGIA+ + + I+E ++V +E +L
Sbjct: 293 TVARSLDKGQPQAVDHVDTIADGIAVRQVG--AQTFPVIQEHVDEVVTVSDDEIATALVL 350
Query: 301 LRKRG-ILVEGTSAVTLAAYWKAKELELIDGVSLL 334
L +RG LVEG A LAA + K E DG +++
Sbjct: 351 LLERGKTLVEGAGATALAAVLEDK-FEYADGETIV 384
>sp|P46493|THD1_HAEIN THREONINE DEHYDRATASE BIOSYNTHETIC (THREONINE DEAMINASE)
>gi|1573745|gb|AAC22398.1| (U32757) threonine deaminase
(ilvA) [Haemophilus influenzae Rd]
Length = 513
Score = 76.1 bits (184), Expect = 6e-13
Identities = 75/288 (26%), Positives = 137/288 (47%), Gaps = 29/288 (10%)
Query: 72 DLYLKLDYLQPTGSFKDRGTYVTIAKLK-EEGINEVVIDSSGNAGISLAAYGLSEGIKVH 130
++++K + QP SFK RG Y I+ L E+ V+ S+GN +A G+K
Sbjct: 48 NIWIKREDRQPVNSFKLRGAYAMISSLSAEQKAAGVIAASAGNHAQGVALSAKQLGLKAL 107
Query: 131 VFLSYDANKEKISRLSALNAK--LHFVDGDRMKVHEEAIRFSRDGNLTYVSHWMNPYFLE 188
+ + + K+ + + LH + D K +AI S++ N+T++ + +P +
Sbjct: 108 IVMPQNTPSIKVDAVRGFGGEVLLHGANFDEAKA--KAIELSKEKNMTFIPPFDHPLVIA 165
Query: 189 GTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIESMPSLVAVQAEGFE 248
G T+A E+ +Q+ DYVF+ VG G G+ G L++ + MP + + E +
Sbjct: 166 GQGTLAMEMLQQVADLDYVFVQVGGG----GLAAGVAILLK----QFMPEIKIIGVESKD 217
Query: 249 SLCKRS---KRKNT-------LADGIAIPEPPRI-EEMKQAIKESSGFCISVGKEETLAS 297
S C ++ K + T ADG+A+ RI +E + ++ + V +E A+
Sbjct: 218 SACLKAALDKGEPTDLTHIGLFADGVAV---KRIGDETFRLCQQYLDDMVLVDSDEVCAA 274
Query: 298 LHWLRKR-GILVEGTSAVTLAAYWKAKELELIDGVSL-LILTGSAKNF 343
+ L + + E + A+ LA K + I+G ++ IL+G+ NF
Sbjct: 275 MKDLFENVRAVAEPSGALGLAGLKKYVKQNHIEGKNMAAILSGANLNF 322
>pir||E82374 threonine dehydratase VC0027 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9654419|gb|AAF93205.1| (AE004094)
threonine dehydratase [Vibrio cholerae]
Length = 510
Score = 74.5 bits (180), Expect = 2e-12
Identities = 77/304 (25%), Positives = 134/304 (43%), Gaps = 35/304 (11%)
Query: 56 LPKLTPAITPIVKDSEDLYLKLDYLQPTGSFKDRGTYVTIAKLKE-EGINEVVIDSSGNA 114
+P+L+ I + +K + QP SFK RG Y ++ L E + V+ S+GN
Sbjct: 32 MPRLSARI------GNQVQIKREDRQPVHSFKLRGAYNMVSHLTEAQKAAGVIAASAGNH 85
Query: 115 GISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAK--LHFVDGDRMKVHEEAIRFSRD 172
+A G GIK + + K+ + + LH + D K EA R S++
Sbjct: 86 AQGMALSGTKLGIKTTIVMPRTTPDIKVEAVRGFGGEVLLHGSNFDEAKA--EAERLSKE 143
Query: 173 GNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGE 232
T+V + +P + G TI E+ +Q DY+F+PVG G G+ K+L
Sbjct: 144 QGYTFVPPFDHPLVIAGQGTIGMEMLQQNGHLDYIFVPVGGGGLAAGVAVLVKQL----- 198
Query: 233 IESMPSLVAVQAEGFESLCKRS----------KRKNTLADGIAIPEPPRI-EEMKQAIKE 281
MP + + E +S C ++ + + ADG+A+ RI +E + ++
Sbjct: 199 ---MPEIQVIAVEPEDSACLKAALDAGKPVVLDQVSMFADGVAV---KRIGDETFRLCQQ 252
Query: 282 SSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELIDGVSL-LILTGS 339
++V +E A++ + + E + A+ LA K E + + G L +L+G+
Sbjct: 253 YIDGHVTVSSDEICAAVKDIFEDTRAIAEPSGALALAGLKKFAEQQQLKGKQLGTVLSGA 312
Query: 340 AKNF 343
NF
Sbjct: 313 NTNF 316
>gi|7305521 serine racemase [Mus musculus] >gi|6448865|gb|AAF08701.1|AF148321_1
(AF148321) serine racemase [Mus musculus]
Length = 339
Score = 73.7 bits (178), Expect = 3e-12
Identities = 79/282 (28%), Positives = 114/282 (40%), Gaps = 36/282 (12%)
Query: 59 LTPAITPIVKDS---EDLYLKLDYLQPTGSFKDRGTYVTIAKL----KEEGINEVVIDSS 111
LTP +T + + +L+ K + Q TGSFK RG I L EE VV SS
Sbjct: 25 LTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTPEEKPKAVVTHSS 84
Query: 112 GNAGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSR 171
GN G +L EGI ++ + A K + A A + + D + R +
Sbjct: 85 GNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYCDPSDESREKVTQRIMQ 144
Query: 172 DGNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMG 231
+ V P + G TIA E+ Q+ L D + +PVG G GI K L
Sbjct: 145 ETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKAL---- 200
Query: 232 EIESMPSLVAVQAEGFES-LCKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSG------ 284
PS+ AE + C +SK K L + PP E + +K S G
Sbjct: 201 ----KPSVKVYAAEPSNADDCYQSKLKGELTPNL---HPP--ETIADGVKSSIGLNTWPI 251
Query: 285 --------FCISVGKEETLASLHWLRKRGILVEGTSAVTLAA 318
F ++ + + L W R + +L+E T+ V LAA
Sbjct: 252 IRDLVDDVFTVTEDEIKYATQLVWGRMK-LLIEPTAGVALAA 292
>gi|11345492 serine racemase [Homo sapiens] >gi|10434972|dbj|BAB14442.1|
(AK023169) unnamed protein product [Homo sapiens]
>gi|11034785|gb|AAG27081.1|AF169974_1 (AF169974) serine
racemase [Homo sapiens]
Length = 340
Score = 70.6 bits (170), Expect = 2e-11
Identities = 74/282 (26%), Positives = 113/282 (39%), Gaps = 36/282 (12%)
Query: 59 LTPAITPIVKDS---EDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINE----VVIDSS 111
LTP +T + + +L+ K + Q TGSFK RG + L + + VV SS
Sbjct: 25 LTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSS 84
Query: 112 GNAGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSR 171
GN G +L EGI ++ + A K + A A + + + A R +
Sbjct: 85 GNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTE 144
Query: 172 DGNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMG 231
+ V P + G TIA E+ Q+ L D + +PVG G GI K L
Sbjct: 145 ETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMLAGIAITVKAL---- 200
Query: 232 EIESMPSLVAVQAEGFES-LCKRSKRKNTLADGIAIPEPPRIEEMKQAIKESSG------ 284
PS+ AE + C +SK K L + P E + +K S G
Sbjct: 201 ----KPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPP-----ETIADGVKSSIGLNTWPI 251
Query: 285 --------FCISVGKEETLASLHWLRKRGILVEGTSAVTLAA 318
F ++ + + L W R + +L+E T+ V +AA
Sbjct: 252 IRDLVDDIFTVTEDEIKCATQLVWERMK-LLIEPTAGVGVAA 292
>gb|AAA67575.1| (M87049) threonine deaminase [Escherichia coli]
Length = 514
Score = 69.5 bits (167), Expect = 6e-11
Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 38/305 (12%)
Query: 63 ITPIVKDSEDLYLKLDYL--------QPTGSFKDRGTYVTIAKLKEEG-INEVVIDSSGN 113
+TP+ K E L +LD + QP SFK RG Y +A L EE + V+ S+GN
Sbjct: 31 VTPLQK-MEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGN 89
Query: 114 AGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAK--LHFVDGDRMKVHEEAIRFSR 171
+A G+K + + K+ + + LH + D K +AI S+
Sbjct: 90 HAQGVAFSSARLGVKALIVMPTATADIKVDAVXGFGGEVLLHGANFDEAK--RKAIELSQ 147
Query: 172 DGNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMG 231
T+V + +P + G T+A E+ +Q D VF+PVG G G+ K+L
Sbjct: 148 QQGFTWVPPFDHPMVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQL---- 203
Query: 232 EIESMPSLVAVQAEGFESLCKRS----------KRKNTLADGIAIPEPPRI-EEMKQAIK 280
MP + + E +S C ++ R A+G+A+ RI +E + +
Sbjct: 204 ----MPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAV---KRIGDETFRLCQ 256
Query: 281 ESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELIDGVSLL-ILTG 338
E I+V + A++ L + E + A+ LA K L I G L IL+G
Sbjct: 257 EYLDDIITVDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSG 316
Query: 339 SAKNF 343
+ NF
Sbjct: 317 ANVNF 321
>sp|P04968|THD1_ECOLI THREONINE DEHYDRATASE BIOSYNTHETIC (THREONINE DEAMINASE)
>gi|68318|pir||DWECTS threonine dehydratase (EC
4.2.1.16), biosynthetic - Escherichia coli
>gi|3891839|pdb|1TDJ| Threonine Deaminase
(Biosynthetic) From E. Coli >gi|146462|gb|AAB59054.1|
(M10313) threonine deaminase [Escherichia coli]
>gi|288533|emb|CAA28577.1| (X04890) threonine deaminase
[Escherichia coli] >gi|1790207|gb|AAC77492.1| (AE000453)
threonine deaminase (dehydratase) [Escherichia coli K12]
>gi|225743|prf||1312306B gene ilvGMEDA cluster
[Escherichia coli]
Length = 514
Score = 69.1 bits (166), Expect = 7e-11
Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 38/305 (12%)
Query: 63 ITPIVKDSEDLYLKLDYL--------QPTGSFKDRGTYVTIAKLKEEG-INEVVIDSSGN 113
+TP+ K E L +LD + QP SFK RG Y +A L EE + V+ S+GN
Sbjct: 31 VTPLQK-MEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGN 89
Query: 114 AGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAK--LHFVDGDRMKVHEEAIRFSR 171
+A G+K + + K+ + + LH + D K +AI S+
Sbjct: 90 HAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKA--KAIELSQ 147
Query: 172 DGNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMG 231
T+V + +P + G T+A E+ +Q D VF+PVG G G+ K+L
Sbjct: 148 QQGFTWVPPFDHPMVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQL---- 203
Query: 232 EIESMPSLVAVQAEGFESLCKRS----------KRKNTLADGIAIPEPPRI-EEMKQAIK 280
MP + + E +S C ++ R A+G+A+ RI +E + +
Sbjct: 204 ----MPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAV---KRIGDETFRLCQ 256
Query: 281 ESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELIDGVSLL-ILTG 338
E I+V + A++ L + E + A+ LA K L I G L IL+G
Sbjct: 257 EYLDDIITVDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSG 316
Query: 339 SAKNF 343
+ NF
Sbjct: 317 ANVNF 321
>gb|AAA24014.1| (K03503) threonine dehydratase [Escherichia coli]
Length = 514
Score = 69.1 bits (166), Expect = 7e-11
Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 38/305 (12%)
Query: 63 ITPIVKDSEDLYLKLDYL--------QPTGSFKDRGTYVTIAKLKEEG-INEVVIDSSGN 113
+TP+ K E L +LD + QP SFK RG Y +A L EE + V+ S+GN
Sbjct: 31 VTPLQK-MEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGN 89
Query: 114 AGISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAK--LHFVDGDRMKVHEEAIRFSR 171
+A G+K + + K+ RL + LH + D K +AI S+
Sbjct: 90 HAQGVAFSSARLGVKALIVMPTATADIKVDRLRGFGGEVLLHGANFDEAK--RKAIELSQ 147
Query: 172 DGNLTYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMG 231
T+V + +P + G T+A E+ +Q D VF+PVG G G + +
Sbjct: 148 QQGFTWVPPFDHPMVIAGQGTLALELLQQDAHLDRVFVPVGGG--------GLAACVAVL 199
Query: 232 EIESMPSLVAVQAEGFESLCKRS----------KRKNTLADGIAIPEPPRI-EEMKQAIK 280
+ MP + + E +S C ++ R A+G+A+ RI +E + +
Sbjct: 200 IKQLMPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAV---KRIGDETFRLCQ 256
Query: 281 ESSGFCISVGKEETLASLHWL-RKRGILVEGTSAVTLAAYWKAKELELIDGVSLL-ILTG 338
E I+V + A++ L + E + A+ LA K L I G L IL+G
Sbjct: 257 EYLDDIITVDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSG 316
Query: 339 SAKNF 343
+ NF
Sbjct: 317 ANVNF 321
>emb|CAC11260.1| (AL445063) probable threonine dehydratase, biodegradative
[Thermoplasma acidophilum]
Length = 406
Score = 68.7 bits (165), Expect = 9e-11
Identities = 67/278 (24%), Positives = 121/278 (43%), Gaps = 27/278 (9%)
Query: 64 TPIVKDS-------EDLYLKLDYLQPTGSFKDRGTYVTIAKLKEEGINEVVIDSS-GNAG 115
TP++K + ++Y KL+ Q TGSFK RG +KL E+ V+ +S GN
Sbjct: 26 TPLIKSTTFGNEYGSEMYFKLENFQKTGSFKSRGALFKFSKLSEDDRRRGVLTASAGNHA 85
Query: 116 ISLAAYGLSEGIKVHVFLSYDANKEKISRLSALNAKLHFVDGDRMKVHEEAIRFSRDGNL 175
+A GI + + +K++ ++ A++ D + H A +R N
Sbjct: 86 QGVAYAAKVNGINAKIVMPEYTIPQKVNAVAGYGAEVILHGFDYDEAHRYADDLARKENR 145
Query: 176 TYVSHWMNPYFLEGTKTIAFEIYEQIKLPDYVFIPVGSGTAFLGIWKGFKELIEMGEIES 235
++ + + + + G TI EI E D + +PVG G GI K
Sbjct: 146 VFIEAFNDRWVISGQGTIGLEIMEDRPDIDTIIVPVGGGGLISGIALAAK------HHNP 199
Query: 236 MPSLVAVQAEGFESLCKRSKRKN---------TLADGIAIPEPPRIEEMKQAIKESSGFC 286
++ +++E +S+ K S R+ ++ DGI++ P + K+
Sbjct: 200 HVRIIGIESELSDSM-KASLREGKIVAHTSGVSICDGISVKYPGDL--TFNIAKDYVDDI 256
Query: 287 ISVGKEETLASLHWLRKR-GILVEGTSAVTLAAYWKAK 323
++V +E +++ L +R I+ E + AV LAA + K
Sbjct: 257 VTVTEESVSKAIYRLFERMKIVAEPSGAVGLAAIMEGK 294
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.138 0.405
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 130504268
Number of Sequences: 2977
Number of extensions: 5605168
Number of successful extensions: 12996
Number of sequences better than 1.0e-10: 48
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 12884
Number of HSP's gapped (non-prelim): 48
length of query: 343
length of database: 189,106,746
effective HSP length: 55
effective length of query: 288
effective length of database: 156,189,961
effective search space: 44982708768
effective search space used: 44982708768
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)