BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0378 (PAB0378) DE:UDP-N-ACETYL-D-MANNOSAMINURONIC ACID
DEHYDROGENASE
(418 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75173 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase P... 830 0.0
pir||B71041 probable UDP-N-acetyl-D-mannosaminuronic acid dehydr... 661 0.0
sp|Q57871|Y428_METJA HYPOTHETICAL PROTEIN MJ0428 >gi|2129342|pir... 324 1e-87
gb|AAC46098.1| (U81973) Cap5O [Staphylococcus aureus] 320 2e-86
gb|AAB49444.1| (U73374) Cap8O [Staphylococcus aureus] 317 1e-85
sp|Q45410|EPSD_BURSO NDP-N-ACETYL-D-GALACTOSAMINURONIC ACID DEHY... 314 1e-84
pir||B82264 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase V... 309 5e-83
gb|AAF67264.1|AF169324_2 (AF169324) BcbB [Pasteurella multocida] 308 7e-83
gb|AAF08248.1|AF170495_9 (AF170495) UDP-N-acetylglucosamine-2-ep... 305 8e-82
pir||B49350 hypothetical protein 379 (nfrC 3' region) - Escheric... 293 3e-78
sp|P27829|WECC_ECOLI UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDR... 291 1e-77
pir||H72358 lipopolysaccharide biosynthesis protein - Thermotoga... 289 3e-77
pir||E69211 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -... 289 5e-77
pir||T44829 probable NDP-N-acetyl-D-galactosaminuronic acid dehy... 287 2e-76
gb|AAF33466.1| (AF233324) 90% identity with E. coli UDP-N-acetyl... 284 2e-75
pir||S30681 hypothetical protein o379 - Escherichia coli >gi|148... 272 4e-72
pir||F75096 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase P... 267 1e-70
gb|AAD56735.1|AF125164_8 (AF125164) UDP-ManNAc dehydrogenase [Ba... 265 7e-70
pir||F71153 probable Vi polysaccharide biosynthesis protein - Py... 262 6e-69
pir||A83252 probable UDP-glucose/GDP-mannose dehydrogenase WbpA ... 208 9e-53
gi|11498204 UDP-glucose dehydrogenase (ugd-2) [Archaeoglobus ful... 207 2e-52
gb|AAF23997.1| (AF035937) WbpO [Pseudomonas aeruginosa] 202 5e-51
pir||C82713 polysaccharide biosynthetic protein XF1183 [imported... 201 2e-50
sp|O05973|UDG_RICPR UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 199 4e-50
gb|AAD40718.1|AF048749_14 (AF048749) putative UDP-glucose-6 dehy... 196 3e-49
sp|Q04972|VIPA_SALTI VI POLYSACCHARIDE BIOSYNTHESIS PROTEIN VIPA... 196 5e-49
pir||H70301 nucleotide sugar dehydrogenase - Aquifex aeolicus >g... 193 3e-48
sp|P39861|CAPL_STAAU CAPL PROTEIN >gi|506708|gb|AAA64651.1| (U10... 191 1e-47
pir||H75095 udp-glucose dehydrogenase (ugd) PAB0770 - Pyrococcus... 189 4e-47
pir||T44509 Vi polysaccharide biosynthetic protein [imported] - ... 189 4e-47
pir||T44520 lipopolysaccharide biosynthesis protein [imported] -... 189 4e-47
gb|AAK41109.1| UDP-glucose 6-dehydrogenase (ugd) [Sulfolobus sol... 189 5e-47
emb|CAB57493.1| (Y18930) udp-glucose dehydrogenase [Sulfolobus s... 189 5e-47
pir||A70067 NDP-sugar dehydrogenase homolog ywqF - Bacillus subt... 187 2e-46
emb|CAC05895.1| (AL391754) putative dehydrogenase [Streptomyces ... 187 2e-46
pir||F69727 biosynthesis of teichuronic acid (UDP-glucose 6-dehy... 184 1e-45
gb|AAA84869.1| (U34305) ORF1; Method: conceptual translation su... 182 5e-45
sp|O54068|UDG_RHIME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 178 1e-43
gb|AAC12870.1| (AF044332) UDP-ManNAc dehydrogenase; RffD [Pectob... 176 5e-43
pir||T46573 UDPglucose 6-dehydrogenase (EC 1.1.1.22) [validated]... 175 7e-43
emb|CAA72087.1| (Y11203) UDP-glucose dehydrogenase [Acetobacter ... 173 3e-42
pir||H83393 probable nucleotide sugar dehydrogenase PA2022 [impo... 173 3e-42
gb|AAF23790.1|AF213822_5 (AF213822) UDP-glucose dehydrogenase [Z... 173 4e-42
gi|10956342 pXO1-95 [Bacillus anthracis] >gi|7474336|pir||G59102... 170 3e-41
gb|AAG26472.1|AF285774_12 (AF285774) putative UDP-glucose dehydr... 170 3e-41
gb|AAG18685.1| (AE004973) UDP-glucose dehydrogenase; Ugd [Haloba... 169 5e-41
pir||F82659 UDP-glucose dehydrogenase XF1606 [imported] - Xylell... 165 1e-39
pir||G69988 NDP-sugar dehydrogenase homolog ytcA - Bacillus subt... 162 5e-39
pir||B83202 probable nucleotide sugar dehydrogenase PA3559 [impo... 162 6e-39
pir||S74698 UDP-glucose dehydrogenase - Synechocystis sp. (strai... 162 9e-39
emb|CAB82012.1| (AL161755) putative nucleotide-sugar dehydrogena... 161 1e-38
sp|O07299|ALGD_PSESH GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|21607... 161 2e-38
pir||C70526 probable UDP-glucose dehydrogenase - Mycobacterium t... 161 2e-38
emb|CAB58323.1| (AL121855) UDP-glucose/GDP-mannose family dehydr... 156 5e-37
gi|11497917 UDP-glucose dehydrogenase (ugd-1) [Archaeoglobus ful... 155 8e-37
gb|AAG19454.1| (AE005038) UDP-glucose dehydrogenase; Udg1 [Halob... 155 8e-37
pir||H83203 GDP-mannose 6-dehydrogenase AlgD PA3540 [imported] -... 153 2e-36
sp|P11759|ALGD_PSEAE GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|65967... 153 4e-36
sp|P51585|ALGD_AZOVI GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|10019... 152 1e-35
gb|AAD43344.1|AF159428_1 (AF159428) putative UDP-glucose dehydro... 147 2e-34
emb|CAA11569.1| (AJ223832) hypothetical protein [Mycobacterium a... 147 2e-34
gb|AAD44217.2|AF143772_23 (AF143772) GdhgA [Mycobacterium avium] 136 6e-31
gb|AAD20371.1| (AF125999) UDP-D-glucose-dehydrogenase gdhgA [Myc... 134 2e-30
dbj|BAA99938.1| (AP001309) UDP-glucose dehydrogenase [Arabidopsi... 130 3e-29
sp|Q47329|UDG5_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 129 5e-29
emb|CAB46919.2| (AJ242946) putative UDP-glucose dehydrogenase [S... 128 1e-28
dbj|BAB11006.1| (AB009054) UDP-glucose dehydrogenase [Arabidopsi... 127 2e-28
gb|AAD50493.1|AF172324_11 (AF172324) UDP-Glc-6-dehydrogenase Ugd... 127 2e-28
sp|Q96558|UGDH_SOYBN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 126 5e-28
sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir... 126 5e-28
pir||T44338 hypothetical protein wbfV [imported] - Vibrio choler... 126 5e-28
gb|AAD45294.1|AF156256_2 (AF156256) putative dehydrogenase [Vibr... 125 7e-28
gb|AAC67251.2| (AF067175) UDP-glucose dehydrogenase [Pasteurella... 125 7e-28
sp|O86422|UDG_PSEAE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 125 1e-27
pir||S70888 nucleotide sugar dehydrogenase homolog - Vibrio chol... 124 2e-27
sp|O33952|UDG8_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 124 2e-27
pir||T51527 UDP-glucose dehydrogenase-like protein - Arabidopsis... 123 5e-27
gb|AAF98561.1|AC013427_4 (AC013427) Strong similarity to UDP-Glu... 122 6e-27
dbj|BAB07427.1| (AP001519) nucleotide sugar dehydrogenase [Bacil... 122 6e-27
gb|AAF04455.1|AF053973_1 (AF053973) UDP-glucose dehydrogenase [P... 122 8e-27
pir||F82417 UDP-glucose 6-dehydrogenase VCA0780 [imported] - Vib... 122 8e-27
gb|AAG35229.1| (AF176369) UDP-glucose-6-dehydrogenase [Escherich... 122 8e-27
gb|AAC45348.1| (U90519) putative UDP-glucose dehydrogenase [Esch... 122 1e-26
dbj|BAA77737.1| (AB008676) UDP-glucose-6-dehydrogenase [Escheric... 121 1e-26
sp|Q19905|UGDH_CAEEL PROBABLE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-G... 121 2e-26
sp|Q04873|UDG_SALTY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 120 3e-26
sp|P76373|UDG_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 119 7e-26
gb|AAF04239.1|AF093225_1 (AF093225) Vps21 [Vibrio cholerae] 119 7e-26
sp|P37791|UDG_SHIFL UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 117 2e-25
sp|Q04872|UDG1_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 117 3e-25
sp|O02373|UGDH_DROME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 115 8e-25
gb|AAC97125.1| (AF001310) UDP-glucose dehydrogenase [Drosophila ... 115 1e-24
sp|P12378|UGDH_BOVIN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 113 4e-24
pir||JC2525 UDP-glucose dehydrogenase (EC 1.1.99.-) - Xanthomona... 113 5e-24
gi|4507813 UDP-glucose dehydrogenase [Homo sapiens] >gi|11435916... 113 5e-24
pir||JE0353 uridine diphosphoglucose dehydrogenase (EC 1.-.-.-) ... 113 5e-24
gi|6678499 UDP-glucose dehydrogenase [Mus musculus] >gi|6136117|... 111 1e-23
pir||A54926 UDPglucose 6-dehydrogenase (EC 1.1.1.22) - bovine >g... 111 2e-23
sp|O70199|UGDH_RAT UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROG... 110 3e-23
pir||A81290 probable UDPglucose 6-dehydrogenase (EC 1.1.1.22) Cj... 110 3e-23
emb|CAB43615.1| (AJ239004) uridine diphosphate glucose dehydroge... 107 2e-22
gb|AAD10180.1| (AF026471) Cps2K [Streptococcus pneumoniae] 106 5e-22
sp|Q07172|UDG_STRPY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 104 1e-21
emb|CAA79813.1| (Z21706) ORF7 [synthetic construct] 103 4e-21
pdb|1DLJ|A Chain A, The First Structure Of Udp-Glucose Dehydroge... 101 2e-20
gb|AAC43311.1| (U15171) UDP-glucose dehydrogenase [Streptococcus... 100 3e-20
emb|CAB05929.1| (Z83335) uridine diphosphate glucose dehydrogena... 99 6e-20
sp|Q57346|UDG_STRPN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 98 1e-19
gi|9632145 PBCV-1 UDP-glucose dehydrogenase [Paramecium bursaria... 98 2e-19
emb|CAA78147.1| (Z12159) uridine diphosphate glucose dehydrogena... 94 2e-18
pir||S69821 NDP-sugar dehydrogenase homolog lmbL - Streptomyces ... 89 9e-17
pir||S44959 lmbL protein - Streptomyces lincolnensis 89 9e-17
pir||S38583 hypothetical protein - rice >gi|414707|emb|CAA53449.... 86 8e-16
>pir||G75173 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase PAB0378 -
Pyrococcus abyssi (strain Orsay)
>gi|5457980|emb|CAB49470.1| (AJ248284)
UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDROGENASE
[Pyrococcus abyssi]
Length = 418
Score = 830 bits (2120), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS
Sbjct: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
KGKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIESTV
Sbjct: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
Query: 121 PPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILA 180
PPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILA
Sbjct: 121 PPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILA 180
Query: 181 EKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELAN 240
EKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELAN
Sbjct: 181 EKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELAN 240
Query: 241 THPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAKLLFEALG 300
THPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAKLLFEALG
Sbjct: 241 THPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAKLLFEALG 300
Query: 301 EANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGTHTILEE 360
EANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGTHTILEE
Sbjct: 301 EANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGTHTILEE 360
Query: 361 AVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLVKEPPKGFIFKGIGRGDV 418
AVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLVKEPPKGFIFKGIGRGDV
Sbjct: 361 AVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLVKEPPKGFIFKGIGRGDV 418
>pir||B71041 probable UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -
Pyrococcus horikoshii >gi|3258047|dbj|BAA30730.1|
(AP000006) 418aa long hypothetical
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Pyrococcus horikoshii]
Length = 418
Score = 661 bits (1688), Expect = 0.0
Identities = 318/418 (76%), Positives = 367/418 (87%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRIAV+GLGYIGLPTAIMFASSG+DV+GYDIR +V++K+N G+AHI+EPEI RL+EV+S
Sbjct: 1 MRIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEVLS 60
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
GKL+ T DLKG++ FIICVQTPLS PDL+YLE AI+T+A+V+++ ALV+IEST+
Sbjct: 61 LGKLKVTDRVEDLKGSNVFIICVQTPLSGDDPDLSYLERAIRTVAEVMDRGALVIIESTI 120
Query: 121 PPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILA 180
PPGTTE+MA+LLE LTGL+EG DFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKA+ LA
Sbjct: 121 PPGTTEKMARLLENLTGLREGVDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAANLA 180
Query: 181 EKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELAN 240
EKLYRSFVKGRIFLT ATTAEMVKLMENTFRDVNIALANEFA LAH+YGVNVYEAIELAN
Sbjct: 181 EKLYRSFVKGRIFLTNATTAEMVKLMENTFRDVNIALANEFALLAHQYGVNVYEAIELAN 240
Query: 241 THPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAKLLFEALG 300
THPRVKIH PGIGVGGHCLPKDPYLLL+N ED GLIR AR+INE MP FAA LLFEAL
Sbjct: 241 THPRVKIHTPGIGVGGHCLPKDPYLLLSNAKEDFGLIRIARRINERMPAFAAGLLFEALE 300
Query: 301 EANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGTHTILEE 360
+AN+ P +A++ VLGLAYKG TDD RNSPAL+F++II VKEVRTYDPYV GTH LE+
Sbjct: 301 KANIKPSEAIIAVLGLAYKGGTDDTRNSPALKFVEIIRNSVKEVRTYDPYVRGTHDSLEK 360
Query: 361 AVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLVKEPPKGFIFKGIGRGDV 418
V+G DAI+IATDH F+ + W+ +G MR+KIIIDGRN++KEPP GFIF+GIGRGDV
Sbjct: 361 VVEGADAIVIATDHPEFKSVNWESIGKSMRHKIIIDGRNIIKEPPVGFIFRGIGRGDV 418
>sp|Q57871|Y428_METJA HYPOTHETICAL PROTEIN MJ0428 >gi|2129342|pir||D64353
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
homolog - Methanococcus jannaschii
>gi|1591131|gb|AAB98413.1| (U67494)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Methanococcus jannaschii]
Length = 427
Score = 324 bits (822), Expect = 1e-87
Identities = 182/410 (44%), Positives = 258/410 (62%), Gaps = 25/410 (6%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
RI VIGLGYIGLPTA M A G DVIG DI V+++ E ++ ++ ++
Sbjct: 12 RICVIGLGYIGLPTASMLAIQGFDVIGVDINEKRVKEIKELSFKTTEKDLMTLVKGAINS 71
Query: 62 GKLRATSDYNDLKGADAFIICVQTPL----SNGVPDLTYLESAIKTIAKVIEKEALVVIE 117
G L+ + AD FIICV TP DLTYL AI++I +E L++IE
Sbjct: 72 GNLKVQTKPEK---ADVFIICVPTPCIECDGEKKCDLTYLNKAIESIKPYLENGNLIIIE 128
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAS 177
ST+PPGTT+ + K L + + YVAH PERV+PG I KELV N R+IGGV EK++
Sbjct: 129 STIPPGTTDDIYKKLSK------DKKIYVAHCPERVLPGSILKELVENDRVIGGVDEKSA 182
Query: 178 ILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
+A+++Y +FV G+I+LT A TAEMVKLMENT+RDVNIALANEFA +A + G+NV+EAIE
Sbjct: 183 EMAKEIYETFVTGKIYLTDAKTAEMVKLMENTYRDVNIALANEFAKIAEEIGINVWEAIE 242
Query: 238 LANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAKLLFE 297
LAN HPRV I +PG GVGGHC+ DP+ ++ ++ LIR AR++N+SMP F + + +
Sbjct: 243 LANKHPRVNILKPGPGVGGHCISIDPWFIVEK-SKNAKLIRTARELNDSMPLFVVEKIKK 301
Query: 298 ALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNG---T 354
+ + D G V + G+ YKG+ DD R SPA + + + + EV+ YD Y
Sbjct: 302 IIKK---DIGK--VAIFGVTYKGNVDDTRESPAEKVVSKLIDEGFEVKCYDKYARDFIYP 356
Query: 355 HTILEEAVKGVDAIIIATDHSMFREIEWDKLGNL---MRNKIIIDGRNLV 401
L+EAV+G D I+I +H ++ + + + N+ ++NKII+D +N++
Sbjct: 357 LNSLDEAVEGADIIVILAEHDEYKNFDKEDIKNIASKVKNKIILDTKNIL 406
>gb|AAC46098.1| (U81973) Cap5O [Staphylococcus aureus]
Length = 420
Score = 320 bits (811), Expect = 2e-86
Identities = 177/424 (41%), Positives = 260/424 (60%), Gaps = 22/424 (5%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M++ V+GLGYIGLPT+IMFA G DV+G DI + ++K+ G I EP + E EV+S
Sbjct: 1 MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEVLS 60
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVP---DLTYLESAIKTIAKVIEKEALVVIE 117
GKL+ ++ + +D FII V TP ++ D++ + A+ +I ++K +++E
Sbjct: 61 SGKLKVSTTP---EASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLKKGNTIIVE 117
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAS 177
ST+ P T + K + E G GED Y+ H PERV+PG+I +ELV+N+RIIGGV++
Sbjct: 118 STIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGVTKACI 177
Query: 178 ILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
+++YR+FV+G + T A TAEM KLMENT+RDVNIALANE + + +NV + IE
Sbjct: 178 EAGKRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIE 237
Query: 238 LANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRF---AAKL 294
+AN HPRV IH+PG GVGGHCL DPY ++A E+ LI+ R+IN SMP + K
Sbjct: 238 MANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQ 297
Query: 295 LFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII--EKDVKEVRTYDPYV- 351
+ +AL V V GL YKGD DD+R SPA + +++ E D+ EV YDP+V
Sbjct: 298 IIKALSGNK-------VTVFGLTYKGDVDDIRESPAFDIYELLNQEPDI-EVCAYDPHVE 349
Query: 352 -NGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLVKEPPKGFIF 410
+ + AVK ++I +DHS F+ + D + M++K+I D +N+VK + ++
Sbjct: 350 LDFVEHDMSHAVKDASLVLILSDHSEFKNLS-DSHFDKMKHKVIFDTKNVVKSSFEDVLY 408
Query: 411 KGIG 414
G
Sbjct: 409 YNYG 412
>gb|AAB49444.1| (U73374) Cap8O [Staphylococcus aureus]
Length = 420
Score = 317 bits (804), Expect = 1e-85
Identities = 177/412 (42%), Positives = 254/412 (60%), Gaps = 22/412 (5%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M++ V+GLGYIGLPT+IMFA G DV+G DI + ++K+ G I EP + E EV+S
Sbjct: 1 MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEVYEEVLS 60
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVP---DLTYLESAIKTIAKVIEKEALVVIE 117
GKL+ ++ + +D FII V TP ++ D++ + A+ +I +EK +++E
Sbjct: 61 SGKLKVSTTP---EASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLEKGNTIIVE 117
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAS 177
ST+ P T + K + E G GED Y+ H PERV+PG+I +ELV+N+RIIGGV++
Sbjct: 118 STIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGVTKACI 177
Query: 178 ILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
+ +YR+FV+G + T A TAEM KLMENT+RDVNIALANE + + +NV IE
Sbjct: 178 EAGKYVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLVVIE 237
Query: 238 LANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRF---AAKL 294
+AN HPRV IH+PG GVGGHCL DPY ++A E+ LI+ R+IN SMP + K
Sbjct: 238 MANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQ 297
Query: 295 LFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII--EKDVKEVRTYDPYV- 351
+ +AL V V GL YKGD DD+R SPA + +++ E D+ EV YDP+V
Sbjct: 298 IIKALSGNK-------VTVFGLTYKGDVDDIRESPAFDIYELLNQEPDI-EVCAYDPHVE 349
Query: 352 -NGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLVK 402
+ + AVK ++I +DHS F+ + D + M++K+I D +N+VK
Sbjct: 350 LDFVEHDMSHAVKDASLVLILSDHSEFKNLS-DSHFDKMKHKVIFDTKNVVK 400
>sp|Q45410|EPSD_BURSO NDP-N-ACETYL-D-GALACTOSAMINURONIC ACID DEHYDROGENASE
>gi|7449841|pir||S77638 probable
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (EC
1.1.1.-) - Pseudomonas solanacearum
>gi|600868|gb|AAA91627.1| (U17898) EpsD [Ralstonia
solanacearum]
Length = 423
Score = 314 bits (796), Expect = 1e-84
Identities = 172/415 (41%), Positives = 256/415 (61%), Gaps = 28/415 (6%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
I+V+GLGYIGLPTA + AS ++IG DI + V+ +N+ HIVEP++ +R VS+G
Sbjct: 12 ISVVGLGYIGLPTATVLASRQRELIGVDINQHAVDTINQARIHIVEPDLDMLVRAAVSQG 71
Query: 63 KLRATSDYNDLKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEKEALVVIESTVP 121
LRAT++ ADAF+I V TP L + PDLTY+E+A K IA V+++ LVV+EST P
Sbjct: 72 YLRATTEPEP---ADAFLIAVPTPFLEDKQPDLTYIEAAAKAIAPVLKRGDLVVLESTSP 128
Query: 122 PGTTERMAKLLEELTG-------LKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
G TE+++ L E L E D VAH PERV+PG + +ELV N RIIGG++
Sbjct: 129 VGATEQLSAWLSEQRSDLSFPHQLGEESDIRVAHCPERVLPGHVLRELVENDRIIGGMTP 188
Query: 175 KASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
+ S A++LY FV+GR +T A TAEM KL EN FRDVNIA ANE + + + GVNV+E
Sbjct: 189 RCSQAAQRLYELFVRGRCIVTDARTAEMCKLTENAFRDVNIAFANELSMICDEIGVNVWE 248
Query: 235 AIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAKL 294
I +AN HPRV I +PG GVGGHC+ DP+ ++ E LIR AR++N++ P +
Sbjct: 249 LISVANRHPRVNILQPGPGVGGHCIAVDPWFIVDAAPESARLIRTAREVNDAKPHYVLDR 308
Query: 295 LFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIK-IIEKDVKEVRTYDPYVNG 353
+ +A + V+ GL++K + DD+R SPA+E ++ ++++ + V +P++
Sbjct: 309 VKQAARRFK----EPVIACFGLSFKANIDDLRESPAIEIVRTMVQQQLGTVLVVEPHIKV 364
Query: 354 THTIL--------EEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNL 400
L E A+ D +++ DH FR+++ D+L +++++ID R +
Sbjct: 365 LPASLEGVELLNAEPALSRADIVVLLVDHQKFRKLDTDRL----QSRVVIDTRGM 415
>pir||B82264 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase VC0918
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9655375|gb|AAF94080.1| (AE004175)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Vibrio cholerae]
Length = 413
Score = 309 bits (782), Expect = 5e-83
Identities = 176/420 (41%), Positives = 255/420 (59%), Gaps = 31/420 (7%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
+++VIGLGYIGLPTA + AS G DV+G D+ V+ +N+G HIVEP++ +R V
Sbjct: 4 KVSVIGLGYIGLPTAAVLASRGLDVVGVDVNAHAVDTINKGEIHIVEPDLDIVVRSAVMT 63
Query: 62 GKLRATSDYNDLKGADAFIICVQTPLS--NGVPDLTYLESAIKTIAKVIEKEALVVIEST 119
GKL+AT + ADAF++ V TP N PDL+Y+E+A KTIA V+ K LVV+EST
Sbjct: 64 GKLKATLT---AEPADAFLVAVPTPFKGDNHEPDLSYIEAAAKTIAPVLAKGNLVVLEST 120
Query: 120 VPPGTTERMAKLLEE----LTGLKE---GEDFYVAHAPERVMPGRIFKELVYNSRIIGGV 172
P GTTE++A+ L E LT ++ D +A+ PERV+PG + +ELV N R+IGGV
Sbjct: 121 SPVGTTEKLAQWLAEARPDLTFPQQKGIAADVKIAYCPERVLPGYVLQELVSNDRVIGGV 180
Query: 173 SEKASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNV 232
S+ S A LY++FVKG +T A TAEM KL EN+FRDVNIA ANE + + +K +NV
Sbjct: 181 SKACSEKAVALYKTFVKGECIVTNARTAEMAKLTENSFRDVNIAFANELSLVCNKLKINV 240
Query: 233 YEAIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAA 292
+E I LAN HPRV I PG GVGGHC+ DP+ ++ + ++ LIR AR++N+ P +
Sbjct: 241 WELIRLANRHPRVSILNPGPGVGGHCIAVDPWFIVNSCPDEAQLIRTAREVNDGKPHWVV 300
Query: 293 KLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIK-IIEKDVKEVRTYDPYV 351
+ +A + ++ LGLA+K D DD+R SPAL+ K + E V ++ +P +
Sbjct: 301 DQVKQAADQFK----KPIIACLGLAFKADIDDLRESPALDITKHLAESKVGQLLAVEPNI 356
Query: 352 ---------NGTHTI-LEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLV 401
G + LE A++ + +++ DH F+ + + K++ID R +V
Sbjct: 357 TELPSKLAKQGIELVSLERALELANIVVVLVDHKEFKAADKTEFA----KKVVIDTRGVV 412
>gb|AAF67264.1|AF169324_2 (AF169324) BcbB [Pasteurella multocida]
Length = 422
Score = 308 bits (781), Expect = 7e-83
Identities = 178/424 (41%), Positives = 252/424 (58%), Gaps = 33/424 (7%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
I+VIGLGYIGLPTA +FA VIG DI V +N+G HIVE ++ + +++ V+KG
Sbjct: 7 ISVIGLGYIGLPTAAVFAQHHVKVIGIDINEHAVNTINQGKIHIVESDLEQVVQQCVNKG 66
Query: 63 KLRATSDYNDLKGADAFIICVQTPL--SNGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
L+A+ ADAF+I V TP +N PDL+Y++SA K I+ V++K L+V+EST
Sbjct: 67 DLKASLTPEP---ADAFLIAVPTPFKGNNYEPDLSYIKSACKMISSVLKKGDLIVLESTS 123
Query: 121 PPGTTERMAKLLEELTG-------LKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVS 173
P GTTE+MA L E L E D +AH PERV+PG + +EL+ N RIIGG++
Sbjct: 124 PVGTTEKMAIWLSEFRHDLTFPQQLGELSDIRIAHCPERVLPGHVMRELIENDRIIGGMT 183
Query: 174 EKASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
K S +A LY++FVKG +T + TAEM KL EN FRDVNIA ANE + + K G+NV+
Sbjct: 184 PKCSQMAVDLYKTFVKGDCIVTNSRTAEMCKLTENAFRDVNIAFANELSIICDKLGINVW 243
Query: 234 EAIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAK 293
E I LAN HPRV I +PG GVGGHC+ DP+ ++ E LI AR +N+S P +
Sbjct: 244 ELINLANRHPRVNILQPGCGVGGHCIAVDPWFIVNKTPELAKLIHTARLVNDSKPEWVIN 303
Query: 294 LLFEALGEA-----NVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIK-IIEKDVKEVRTY 347
+ A+ EA N D + LGLA+K D DD+R SPAL+ K + K ++
Sbjct: 304 QVNNAVIEALQKNPNKTLQDIKIACLGLAFKPDIDDLRESPALKITKQLAAKYPNQITAV 363
Query: 348 DPYV----------NGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDG 397
+P + N H+ L++A++ D +++ DH F+EI+ + N I+D
Sbjct: 364 EPNIEALPEQLITQNIKHSSLQQALETCDVLVVLVDHKEFKEIQTTSV-----NATIVDT 418
Query: 398 RNLV 401
+ ++
Sbjct: 419 KGIL 422
>gb|AAF08248.1|AF170495_9 (AF170495) UDP-N-acetylglucosamine-2-epimerase [Pasteurella
haemolytica]
Length = 423
Score = 305 bits (772), Expect = 8e-82
Identities = 169/403 (41%), Positives = 245/403 (59%), Gaps = 27/403 (6%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
I+V+GLGYIGLPTA +FA G +VIG D+ + V+ +N+G HIVEP++ + + VS G
Sbjct: 7 ISVVGLGYIGLPTATVFAQHGLNVIGVDVNQHAVDHINQGKIHIVEPDLDVAVHQCVSSG 66
Query: 63 KLRATSDYNDLKGADAFIICVQTPLSNG--VPDLTYLESAIKTIAKVIEKEALVVIESTV 120
KL+AT A+AF+I V TP PDL+Y+++A K IA V+EK LV++EST
Sbjct: 67 KLKATLTPEP---AEAFLIAVPTPFKGQDYEPDLSYIQAACKAIAPVLEKGNLVILESTS 123
Query: 121 PPGTTERMAKLLEELTG-------LKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVS 173
P G TE+MA+ L E E D +AH PERV+PG++ EL+ N RI+GG++
Sbjct: 124 PVGATEQMAEWLAEYRPELSFPQQAGEDSDIRIAHCPERVLPGQVMHELIENDRIVGGMT 183
Query: 174 EKASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
K S+ A LY++FVKG +T A TAEM KL EN+FRDVNIA ANE + + + +NV+
Sbjct: 184 NKCSVQAVNLYKTFVKGDCIVTNARTAEMCKLTENSFRDVNIAFANELSIICDRLDINVW 243
Query: 234 EAIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAK 293
E I LAN HPRV I +PG GVGGHC+ DP+ ++ + +IR R++N+ P +
Sbjct: 244 ELIALANRHPRVNILQPGCGVGGHCIAVDPWFIVNKTPDLAKIIRTGREVNDHKPEWVIS 303
Query: 294 LLFEALGEANVDPGDAV----VLVLGLAYKGDTDDVRNSPALEFI-KIIEKDVKEVRTYD 348
+ EA+ A G ++ + LGLA+K D DD+R SPAL+ K+ EK +V +
Sbjct: 304 KMNEAVIYALQKTGKSIDQIKIACLGLAFKPDIDDLRESPALKITEKLAEKYPNQVFAVE 363
Query: 349 PYV----------NGTHTILEEAVKGVDAIIIATDHSMFREIE 381
P V N + ++EA++ D +++ DHS F+ ++
Sbjct: 364 PNVEELPKKLANKNISLISVDEALEVADVVVVLVDHSEFKLVK 406
>pir||B49350 hypothetical protein 379 (nfrC 3' region) - Escherichia coli
Length = 420
Score = 293 bits (741), Expect = 3e-78
Identities = 166/405 (40%), Positives = 245/405 (59%), Gaps = 25/405 (6%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
I+VIGLGYIGLPTA FAS VIG DI + V+ +NRG HIVEP++ ++ V G
Sbjct: 6 ISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVEPDLASVVKTAVEGG 65
Query: 63 KLRATSDYNDLKGADAFIICVQTPLSNG-VPDLTYLESAIKTIAKVIEKEALVVIESTVP 121
LRA++ + ADA++I V TP PD+TY+ESA ++IA V++K ALV++EST P
Sbjct: 66 FLRASTTPVE---ADAWLIAVPTPFKGDHEPDMTYVESAARSIAPVLKKGALVILESTSP 122
Query: 122 PGTTERMAKLLEELTG-------LKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
G+TE+MA+ L E+ + E D +A+ PERV+PG++ EL+ N R+IGG++
Sbjct: 123 VGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPERVLPGQVMVELIKNDRVIGGMTP 182
Query: 175 KASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
S A +LY+ F++G +T + TAEM KL EN+FRDVNIA ANE + + G+NV+E
Sbjct: 183 VCSARASELYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQGINVWE 242
Query: 235 AIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRF---- 290
I LAN HPRV I +PG GVGGHC+ DP+ ++A + LIR AR++N+ P +
Sbjct: 243 LIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVAQNPQQARLIRTAREVNDHKPFWVIDQ 302
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEK-DVKEVRTYDP 349
+ + L + + + GLA+K + DD+R SPA+E ++I + E +P
Sbjct: 303 VKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPAMEIAELIAQWHSGETLVVEP 362
Query: 350 YVN-------GTHTI--LEEAVKGVDAIIIATDHSMFREIEWDKL 385
++ G T+ L+EA+ D +++ DHS F+ I D +
Sbjct: 363 NIHQLPKKLTGLCTLAQLDEALATADVLVMLVDHSQFKVINGDNV 407
>sp|P27829|WECC_ECOLI UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDROGENASE (UDP-MANNACA
DEHYDROGENASE) >gi|7449840|pir||F65182 UDP-ManNAc
dehydrogenase - Escherichia coli
>gi|2367284|gb|AAC76792.1| (AE000455)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase;
synthesis of enterobacterial common antigen (ECA)
[Escherichia coli K12]
Length = 420
Score = 291 bits (736), Expect = 1e-77
Identities = 165/405 (40%), Positives = 244/405 (59%), Gaps = 25/405 (6%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
I+VIGLGYIGLPTA FAS VIG DI + V+ +NRG HIVEP++ ++ V G
Sbjct: 6 ISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVEPDLASVVKTAVEGG 65
Query: 63 KLRATSDYNDLKGADAFIICVQTPLSNG-VPDLTYLESAIKTIAKVIEKEALVVIESTVP 121
LRA++ + AD ++I V TP PD+TY+ESA ++IA V++K ALV++EST P
Sbjct: 66 FLRASTTPVE---ADRWLIAVPTPFKGDHEPDMTYVESAARSIAPVLKKGALVILESTSP 122
Query: 122 PGTTERMAKLLEELTG-------LKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
G+TE+MA+ L E+ + E D +A+ PERV+PG++ EL+ N R+IGG++
Sbjct: 123 VGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPERVLPGQVMVELIKNDRVIGGMTP 182
Query: 175 KASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
S A +LY+ F++G +T + TAEM KL EN+FRDVNIA ANE + + G+NV+E
Sbjct: 183 VCSARASELYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQGINVWE 242
Query: 235 AIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRF---- 290
I LAN HPRV I +PG GVGGHC+ DP+ ++A + LIR AR++N+ P +
Sbjct: 243 LIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVAQNPQQARLIRTAREVNDHKPFWVIDQ 302
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEK-DVKEVRTYDP 349
+ + L + + + GLA+K + DD+R SPA+E ++I + E +P
Sbjct: 303 VKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPAMEIAELIAQWHSGETLVVEP 362
Query: 350 YVN-------GTHTI--LEEAVKGVDAIIIATDHSMFREIEWDKL 385
++ G T+ L+EA+ D +++ DHS F+ I D +
Sbjct: 363 NIHQLPKKLTGLCTLAQLDEALATADVLVMLVDHSQFKVINGDNV 407
>pir||H72358 lipopolysaccharide biosynthesis protein - Thermotoga maritima
(strain MSB8) >gi|4981101|gb|AAD35668.1|AE001733_5
(AE001733) lipopolysaccharide biosynthesis protein
[Thermotoga maritima]
Length = 434
Score = 289 bits (733), Expect = 3e-77
Identities = 166/416 (39%), Positives = 250/416 (59%), Gaps = 20/416 (4%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
+ VIGLGY+GLP A+ A +G+ V+G+DI++ V+ VNRG +I + + E L+++V KG
Sbjct: 13 LGVIGLGYVGLPLAVEKAKAGYRVLGFDIQKKRVDMVNRGENYIGDV-VDEDLKDLVEKG 71
Query: 63 KLRATSDYNDLKGADAFIICVQTPLSN-GVPDLTYLESAIKTIAKVIEKEALVVIESTVP 121
+RAT+D++++K D ICV TPL PDLTY+ + K IAK + +E LVV+EST
Sbjct: 72 MIRATTDFSEMKNCDVVTICVPTPLGKYKEPDLTYVINTAKEIAKYLHREMLVVLESTTY 131
Query: 122 PGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILAE 181
PGTTE + + E TGLK G+DFY+A +PERV PG + +++GGV+EK + LA+
Sbjct: 132 PGTTEEVVLPILESTGLKVGKDFYLAFSPERVDPGNKIYKTKNTPKVVGGVTEKCTELAK 191
Query: 182 KLYRSFVKGRIF-LTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELAN 240
LY + ++ + +++ AEM K++ENTFR VNI+L NE A +A + G+N++E I+ A
Sbjct: 192 ILYENVLEAPVHTVSSPRAAEMAKVLENTFRLVNISLINEVAIVARRMGINIWEVIDAAA 251
Query: 241 THP-RVKIHRPGIGVGGHCLPKDPYLL---LANVDEDLGLIRKARKINESMPRFAAKLLF 296
T P PG G GGHC+P DP+ L D L L+ A +IN+ MP + +
Sbjct: 252 TKPFGFMPFYPGPGAGGHCIPIDPFYLAYKAKEYDVRLDLVEMAGEINDFMPEYVVMRVQ 311
Query: 297 EALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYV----- 351
+ L E + VL+LG+AYKGD DD R SPAL+ +EK V +DPYV
Sbjct: 312 DILNERKKPLNGSKVLLLGVAYKGDIDDTRESPALKVWDHLEKKKAVVEFFDPYVPEVKR 371
Query: 352 ----NGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLVKE 403
+ + EE +KGVD ++I T H +++D + + ++ D +N+ K+
Sbjct: 372 GDRIHRRVELTEEYLKGVDIVVITTAHK--NGVDYDFV--VKNAPVVFDTKNITKD 423
>pir||E69211 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621926|gb|AAB85334.1| (AE000860)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Methanobacterium thermoautotrophicum]
Length = 431
Score = 289 bits (731), Expect = 5e-77
Identities = 170/429 (39%), Positives = 241/429 (55%), Gaps = 18/429 (4%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
RIAV GLG+IGLPTA +FA +G V G DI + VEKVN G + ++EP + E + EVV
Sbjct: 5 RIAVFGLGHIGLPTAALFARAGFKVTGVDINPETVEKVNIGRSPVLEPGLDELVAEVVGT 64
Query: 62 GKLRATSDYNDLKG-ADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIEST 119
G L AT D ++ II V TP+ S DL+ + SA +TI++ ++K LV++EST
Sbjct: 65 GNLGATMDGERAAAESEVMIIVVPTPVNSENTSDLSAVISAAETISRGLKKGDLVIVEST 124
Query: 120 VPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASIL 179
VPPG + + + E TGLK EDF +A+ PER +P E+ N+R+IGG +++
Sbjct: 125 VPPGACQNVVLPILEKTGLKVSEDFGLAYTPERALPNNTLHEMQNNARVIGGADPESARR 184
Query: 180 AEKLYRSFVKGRIFLTT-ATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIEL 238
A LYR G + + TAEMVKLMENT+RD NIALANE A + G++ AIE
Sbjct: 185 AAALYRRITSGEVIVVDDLMTAEMVKLMENTYRDTNIALANELAVICEALGIDAINAIEA 244
Query: 239 ANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDE---DLGLIRKARKINESMPRFAAKLL 295
AN HPRV IH PG GVGGHCL DPY ++ + LIR AR++NESMP +++
Sbjct: 245 ANHHPRVNIHTPGPGVGGHCLSIDPYFIVEMAERKGVPARLIRTAREVNESMPLHVLEIV 304
Query: 296 FEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVN--- 352
E L + V +LG+AYKGD D R +P + + + V DP+V+
Sbjct: 305 RETLESRGKTLKGSNVGILGVAYKGDVADARETPTRPLVAALLSEGARVLVNDPHVSPEI 364
Query: 353 ----GTHTILEEAVKGVDAIIIATDHSMFREIEWDKL--GNLMRNKIIIDGRNLVKEPPK 406
G + E D +++ TDH+ + EI + + G + + ++D +
Sbjct: 365 IRGMGVEPVSLEEALNSDCVVLMTDHTEYLEITPEMIPGGIFICTRPVMDPERF---RTR 421
Query: 407 GFIFKGIGR 415
G F+G+GR
Sbjct: 422 GITFRGVGR 430
>pir||T44829 probable NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase
[imported] - Acinetobacter lwoffii
>gi|6009990|emb|CAB57197.1| (AJ243431) putative
NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase
[Acinetobacter lwoffii]
Length = 417
Score = 287 bits (726), Expect = 2e-76
Identities = 166/401 (41%), Positives = 234/401 (57%), Gaps = 24/401 (5%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
I VIGLGYIGLPTA FA+ G V G D+ + V+ +N+G HIVEP++ +R+VV++G
Sbjct: 8 ICVIGLGYIGLPTAATFAAHGVKVTGVDVNQHAVDMINQGKVHIVEPDLDALVRDVVAQG 67
Query: 63 KLRATSDYNDLKGADAFIICVQTPLSNGV-PDLTYLESAIKTIAKVIEKEALVVIESTVP 121
KL A + ADA+I+ V TP + PDL Y+E+A K +A ++ LV++EST P
Sbjct: 68 KLSAQLAPTE---ADAYIVAVPTPFKDDYQPDLKYIEAASKALAPFLKSGNLVILESTSP 124
Query: 122 PGTTERMAKLLEELTG-----LKEGE--DFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
TE+M+ L E ++GE D VAH PERV+PG++ +EL+ N RIIGG++
Sbjct: 125 VEATEQMSAWLSEARPDLSFPQQKGEEADILVAHCPERVLPGKVLQELISNDRIIGGMTP 184
Query: 175 KASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
+ S A LY+ FVKG T A TAEM KL EN+FRDVNIA ANE + + K +NV+E
Sbjct: 185 RCSKAACDLYKIFVKGACIETNARTAEMCKLTENSFRDVNIAFANELSVICDKLDINVWE 244
Query: 235 AIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFA--- 291
I LAN HPRV I +PG GVGGHC+ DP+ ++A E LIR AR++N++ P +
Sbjct: 245 LISLANRHPRVNILQPGPGVGGHCIAVDPWFIVAKTPEQARLIRTAREVNDAKPEWVIDQ 304
Query: 292 AKLLFEALGEANVDP--GDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
K+ +AN D + GLA+K D DD+R SPALE K + + + +P
Sbjct: 305 VKIKIADFLQANPTKTIQDVTIACYGLAFKPDIDDLRESPALEITKKLAEQGFNILAIEP 364
Query: 350 YVNGTHTILEEAVKGV--------DAIIIATDHSMFREIEW 382
++ L +K + D +I DH F+ + +
Sbjct: 365 NIHELPAKLPSNIKLIALKEHQQADIHLILVDHRQFKNMNF 405
>gb|AAF33466.1| (AF233324) 90% identity with E. coli
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
(WECC) (SP:P27829); contains similarity to Pfam family
PF00984 (UDP-glucose/GDP-mannose dehydrogenase family),
score=633.4, E=1.2e-186, N=1 [Salmonella typhimurium >
Length = 420
Score = 284 bits (718), Expect = 2e-75
Identities = 168/420 (40%), Positives = 246/420 (58%), Gaps = 29/420 (6%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
I+VIGLGYIGLPTA FAS VIG DI + V+ +NRG HIVEP +G ++ V G
Sbjct: 6 ISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDIINRGEIHIVEPALGNVVKMAVEGG 65
Query: 63 KLRATSDYNDLKGADAFIICVQTPLSNGV-PDLTYLESAIKTIAKVIEKEALVVIESTVP 121
LRAT+ + ADA++I V TP PD+ Y+E+A K+IA V++K ALV++EST P
Sbjct: 66 FLRATTTPVE---ADAYLIAVPTPFKGDHDPDMAYVEAAAKSIAPVLKKGALVILESTSP 122
Query: 122 PGTTERMAKLLEEL-TGLK------EGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
G TE+MA L + T L E D +A+ PERV+PG++ EL+ N R+IGG++
Sbjct: 123 VGATEQMAGWLAGMRTDLTFPQQAGEQADVNIAYCPERVLPGQVMVELIKNDRVIGGMTP 182
Query: 175 KASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
S A LY+ F++G +T + TAEM KL EN+FRDVNIA ANE + + + G+NV+E
Sbjct: 183 VCSARASALYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICAEQGINVWE 242
Query: 235 AIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAA-- 292
I LAN HPRV I +PG GVGGHC+ DP+ ++A + LIR AR++N+ P +
Sbjct: 243 LIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVAQNPQQARLIRTAREVNDGKPHWVVDQ 302
Query: 293 --KLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII------EKDVKE- 343
+ + L + + + GLA+K + DD+R SPA+ + I E V E
Sbjct: 303 VKAAVTDCLAATDKRASEVKIACFGLAFKPNIDDLRESPAMGIAQSIARWHSGETLVVEP 362
Query: 344 -VRTYDPYVNGTHTI--LEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNL 400
+R ++G T+ L+ A+ D +++ DH F+ I G+ + + ++D + +
Sbjct: 363 NIRQLPKKLDGLCTLAKLDAALAAADVLVMLVDHDEFKAIP----GDAVHQRYVVDTKGV 418
>pir||S30681 hypothetical protein o379 - Escherichia coli
>gi|148190|gb|AAA67587.1| (M87049) possibly rffD;
(UDP-ManNAc dehydrogenase) [Escherichia coli]
Length = 379
Score = 272 bits (689), Expect = 4e-72
Identities = 150/347 (43%), Positives = 217/347 (62%), Gaps = 16/347 (4%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
I+VIGLGYIGLPT FAS VIG DI + V+ +NRG HIVEP++ ++ V G
Sbjct: 6 ISVIGLGYIGLPTRA-FASRQKQVIGVDINQHAVDTINRGEIHIVEPDLASVVKTAVEGG 64
Query: 63 KLRATSDYNDLKGADAFIICVQTPLSNG-VPDLTYLESAIKTIAKVIEKEALVVIESTVP 121
LRA++ + AD ++I V TP PD+TY+ESA ++IA V++K ALV++EST P
Sbjct: 65 FLRASTTPVE---ADRWLIAVPTPFKGDHEPDMTYVESAARSIAPVLKKGALVILESTSP 121
Query: 122 PGTTERMAKLLEELTG-------LKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
G+TE+MA+ L E+ + E D +A+ PERV+PG++ EL+ N R+IGG++
Sbjct: 122 VGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPERVLPGQVMVELIKNDRVIGGMTP 181
Query: 175 KASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
S A +LY+ F++G +T + TAEM KL EN+FRDVNIA ANE + + G+NV+E
Sbjct: 182 VCSARASELYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQGINVWE 241
Query: 235 AIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRF---- 290
I LAN HPRV I +PG GVGGHC+ DP+ ++A + LIR AR++N+ P +
Sbjct: 242 LIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVAQNPQQARLIRTAREVNDHKPFWVIDQ 301
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII 337
+ + L + + + GLA+K + DD+R SPA+E ++I
Sbjct: 302 VKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPAMEIAELI 348
>pir||F75096 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase PAB0776 -
Pyrococcus abyssi (strain Orsay)
>gi|5458587|emb|CAB50075.1| (AJ248286)
UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDROGENASE
[Pyrococcus abyssi]
Length = 448
Score = 267 bits (676), Expect = 1e-70
Identities = 169/427 (39%), Positives = 248/427 (57%), Gaps = 16/427 (3%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVE-PEIGERLREVVSK 61
IAV GLG +GLP A +FA +G VIG DI VV VN G HI E P + E +++ V
Sbjct: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
Query: 62 GKLRATSD-YNDLKGADAFIICVQTPLSN-GVPDLTYLESAIKTIAKVIEKEALVVIEST 119
G+L+AT+D K AD II V T + G L + + I+K +EK +V+ E+T
Sbjct: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
Query: 120 VPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYN-SRIIGGVSEKASI 178
+PPGTTE + +LE+ +GLK G DF +AHAPER M G +++ +I+G E+
Sbjct: 143 MPPGTTESLIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
Query: 179 LAEKLYRSFV-KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
+Y + KG I +++ AE VK+ E +RDVNIALANE A ++G++ E
Sbjct: 201 AVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFN 260
Query: 238 LANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKINESMPRFAAKLLF 296
ANT P +H PG GVGGHC+P P+ ++ + ++ LIR AR+IN+SMPR +L
Sbjct: 261 AANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVELTV 320
Query: 297 EALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGTH- 355
AL +A + +LVLGL ++G + SPA++ I+ +++ EV YDP
Sbjct: 321 RALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLCTREDA 380
Query: 356 ----TILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLV--KEPPK-GF 408
+E K VDAI+I TDH F+ ++ ++ +R K+I+DGRN++ +E K GF
Sbjct: 381 ERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVIHPEEAKKLGF 440
Query: 409 IFKGIGR 415
I+KG+GR
Sbjct: 441 IYKGVGR 447
>gb|AAD56735.1|AF125164_8 (AF125164) UDP-ManNAc dehydrogenase [Bacteroides fragilis]
Length = 408
Score = 265 bits (670), Expect = 7e-70
Identities = 160/417 (38%), Positives = 237/417 (56%), Gaps = 30/417 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M +GLGYIGLPTAI+ A G V G DI VVE N G HI+EP + + L EVV+
Sbjct: 1 MDACFMGLGYIGLPTAIIAAKHGVKVTGVDINPKVVEMTNEGKLHIIEPGMQDILEEVVA 60
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIEST 119
G L A++ +DA+ + V TP N PD++Y+E+A + I +++ L VIEST
Sbjct: 61 NGMLTASTIPTV---SDAYFMVVPTPFKGNHEPDISYVEAATRAIIPFLKEGDLYVIEST 117
Query: 120 VPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASIL 179
P GTT +MA L+ L + Y+A+ PERV+PG + ELV+N R+IGG+ E+++
Sbjct: 118 SPVGTTGKMADLIFSLRPELRCK-IYIAYCPERVLPGNVIYELVHNDRVIGGIDERSTDK 176
Query: 180 AEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELA 239
A + Y FVKG++ T TAEM KL EN+ RDV IA ANE + + K G+NV+E I+LA
Sbjct: 177 AIEFYSQFVKGKLHKTDCKTAEMCKLTENSSRDVQIAFANELSLICDKAGINVWELIDLA 236
Query: 240 NTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAKLLFEAL 299
N HPRV I +P GVGGHC+ DPY + A+ + +I KAR+IN + A+ + +
Sbjct: 237 NKHPRVNILQPSCGVGGHCIAVDPYFITADFPIESQIIAKAREINNYKAFWCAEKVENEM 296
Query: 300 GEANVDPG-DAVVLVLGLAYKGDTDDVRNSPALEF------------IKIIEKDVKEVRT 346
+ + G ++ ++GLA+K D DD+R +PA I ++E +V E +
Sbjct: 297 LKFEIKYGRKPIIAMMGLAFKPDIDDLREAPAKYITTKVMQSCNNADILVVEPNVVEHKV 356
Query: 347 YDPYVNGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLVKE 403
+ T ++A D I+ HS+F+ + +D NK+I+D + K+
Sbjct: 357 F------KLTNYKDAYAKADIIVFLVAHSVFKTLLYDD------NKVILDFCGIYKK 401
>pir||F71153 probable Vi polysaccharide biosynthesis protein - Pyrococcus
horikoshii >gi|3256832|dbj|BAA29515.1| (AP000002) 455aa
long hypothetical Vi polysaccharide biosynthesis protein
[Pyrococcus horikoshii]
Length = 455
Score = 262 bits (662), Expect = 6e-69
Identities = 158/420 (37%), Positives = 238/420 (56%), Gaps = 26/420 (6%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
I ++GLGY+GLP A+ F S +VIGYDI ++ + + ++I + E ++
Sbjct: 20 IGIVGLGYVGLPLAVAF-SKKFNVIGYDINTKKIDSLKKRKSYIEDVRDDE-----INLN 73
Query: 63 KLRATSDYNDLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIESTVP 121
+L+ T+D DLK D II V TPL + PDL+Y++ A +T+ +++ + V++EST
Sbjct: 74 RLQPTNDPEDLKKCDFIIITVPTPLREDKTPDLSYVKDAARTVGRILRRGQFVILESTTY 133
Query: 122 PGTTER-MAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILA 180
PGTTE + +LEE +GLK EDF VA++PER+ PG ++ +++GG++ + + LA
Sbjct: 134 PGTTEEVLIPILEEESGLKVIEDFGVAYSPERIDPGNKRYKIENTPKVVGGLTPEFTELA 193
Query: 181 EKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELAN 240
LY S ++ + + TAE VK++EN FR+VNIAL NE A + K G++++E IE A
Sbjct: 194 SMLYGSVIEKIVPVKDCKTAEAVKMLENVFRNVNIALVNELALIFEKMGIDIWEVIEAAK 253
Query: 241 THP-RVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRK----ARKINESMPRFAAKLL 295
T P PG GVGGHC+P DPY L + G+I + A +IN MP L
Sbjct: 254 TKPYGFMAFYPGPGVGGHCIPVDPYYLSYRA-KQFGIIPRFIETAGEINNYMPVHTVNLA 312
Query: 296 FEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGTH 355
L + A V VLGLAYK D D R SPA++ I+ + + +V+ YDPYV
Sbjct: 313 ETGLRKIGRKIRGAKVAVLGLAYKADISDTRESPAIKIIEELIERGAQVKVYDPYVKSVR 372
Query: 356 T---------ILEEAVKGVDAIIIATDHSMFREIEWDKL---GNLMRNKIIIDGRNLVKE 403
T LE+ +K D +I TDHS+F+E + L G K+I+D RN+ ++
Sbjct: 373 TKFGTFRVTETLEDILKWSDCVIFVTDHSLFKEKMEEILKIFGETSTKKVIVDSRNIFEK 432
>pir||A83252 probable UDP-glucose/GDP-mannose dehydrogenase WbpA PA3159
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|1545847|gb|AAC45852.1| (U50396) WbpA [Pseudomonas
aeruginosa] >gi|9949274|gb|AAG06547.1|AE004739_9
(AE004739) probable UDP-glucose/GDP-mannose
dehydrogenase WbpA [Pseudomonas aeruginosa]
Length = 436
Score = 208 bits (524), Expect = 9e-53
Identities = 134/422 (31%), Positives = 216/422 (50%), Gaps = 30/422 (7%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRG---IAHIVEPEIGERLREVV 59
I ++GLGY+GLP + + + G DV+G DI V+K+N G I HI + +I +
Sbjct: 18 IGIVGLGYVGLPLMLRYNAIGFDVLGIDIDDVKVDKLNAGQCYIEHIPQAKIAK-----A 72
Query: 60 SKGKLRATSDYNDLKGADAFIICVQTPLSN-GVPDLTYLESAIKTIAKVIEKEALVVIES 118
AT+D++ + DA I+CV TPL+ PD++++ + + + +V +ES
Sbjct: 73 RASGFEATTDFSRVSECDALILCVPTPLNKYREPDMSFVINTTDALKPYLRVGQVVSLES 132
Query: 119 TVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASI 178
T PGTTE + GL G D Y+ ++PER PG E ++IGG + +
Sbjct: 133 TTYPGTTEEELLPRVQEGGLVVGRDIYLVYSPEREDPGNPNFETRTIPKVIGGHTPQCLE 192
Query: 179 LAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIEL 238
+ LY + + +++ AEM KL+EN R VNI L NE +A + G++++E ++
Sbjct: 193 VGIALYEQAIDRVVPVSSTKAAEMTKLLENIHRAVNIGLVNEMKIVADRMGIDIFEVVDA 252
Query: 239 ANTHP-RVKIHRPGIGVGGHCLPKDPYLLLANVDE---DLGLIRKARKINESMPRFAAKL 294
A T P + PG G+GGHC+P DP+ L E I + ++N++MP +
Sbjct: 253 AATKPFGFTPYYPGPGLGGHCIPIDPFYLTWKAREYGLHTRFIELSGEVNQAMPEYVLGK 312
Query: 295 LFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVN-- 352
L + L EA + VLVLG+AYK + DD+R SP++E +++IE V DP+V
Sbjct: 313 LMDGLNEAGRALKGSRVLVLGIAYKKNVDDMRESPSVEIMELIEAKGGMVAYSDPHVPVF 372
Query: 353 ----------GTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLVK 402
+ + E + DA+++ATDH F + E K K+++D R +
Sbjct: 373 PKMREHHFELSSEPLTAENLARFDAVVLATDHDKF-DYELIK----AEAKLVVDSRGKYR 427
Query: 403 EP 404
P
Sbjct: 428 SP 429
>gi|11498204 UDP-glucose dehydrogenase (ugd-2) [Archaeoglobus fulgidus]
>gi|7431387|pir||D69324 UDP-glucose dehydrogenase
(ugd-2) homolog - Archaeoglobus fulgidus
>gi|2650028|gb|AAB90645.1| (AE001064) UDP-glucose
dehydrogenase (ugd-2) [Archaeoglobus fulgidus]
Length = 465
Score = 207 bits (521), Expect = 2e-52
Identities = 146/440 (33%), Positives = 228/440 (51%), Gaps = 46/440 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+IA++G GY+G+ T I FA GH+++ D+ VE +N I E + E +++ +
Sbjct: 43 MKIAILGSGYVGIVTGIGFAELGHEIVFIDVDERKVEMLNSSKPPIYERGLEELMKK--N 100
Query: 61 KGKLRATSDYND-LKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEKE---ALVV 115
+GK RAT+DY + L+ ++ ICV TP +G DL Y ESA K I K ++ +VV
Sbjct: 101 RGKYRATTDYREALESSELTFICVGTPSKGDGSIDLKYAESASKEIGKALKNNDNFHVVV 160
Query: 116 IESTVPPGTTE-RMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV-S 173
++STV PGTTE ++ ++E+ +G K EDF +A PE + G + RI+ GV
Sbjct: 161 VKSTVVPGTTEDKIKPIIEKESGKKAFEDFGLAMNPEFLREGNAVYDFFNPDRIVIGVKD 220
Query: 174 EKASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
E+ + E+LY+ F ++ +T TAEM+K N F I+ ANE + K ++VY
Sbjct: 221 ERTKSVLEELYKPFDCPKL-ITEIKTAEMIKYASNAFLATKISFANEIGNICKKLRIDVY 279
Query: 234 EAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLG----LIRKARKINESM 287
+ E R+ R GIG GG C PKD L+ E+LG +++ ++NE
Sbjct: 280 KVFEGVGLDHRINPSFFRAGIGFGGSCFPKDVRALIRK-SEELGENPKILKAVMEVNERQ 338
Query: 288 PRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTY 347
P +LL + + + VLGLA+K DTDDVR S A+ +K + ++ E+ Y
Sbjct: 339 PLKMIELLKKHIPNLR----GKKIGVLGLAFKPDTDDVRESRAIPIVKALLEEGAEIIAY 394
Query: 348 DP--------------YVNGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKI 393
DP Y N E+ + DA++I T+ F E+++ KI
Sbjct: 395 DPKAIENFRKFFPQVEYANSA----EDVITKSDAVLIVTEWKEFEELDYS-------GKI 443
Query: 394 IIDGRNLVKEPPKGFIFKGI 413
+IDGR + K + I+KG+
Sbjct: 444 VIDGRRVEKAMKEAKIYKGV 463
>gb|AAF23997.1| (AF035937) WbpO [Pseudomonas aeruginosa]
Length = 422
Score = 202 bits (509), Expect = 5e-51
Identities = 130/419 (31%), Positives = 229/419 (54%), Gaps = 23/419 (5%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
+++AV+GLGY+GLP A+ F V+G+DI + + ++ +GI +E + E L+E
Sbjct: 4 LKVAVVGLGYVGLPLAVEFGKK-RTVVGFDINQGRIAELRQGIDSTLEVDAAE-LKEA-- 59
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIEST 119
+L T + DL+ + FI+ V TP+ + PDLT L A ++I KV++K +V+ EST
Sbjct: 60 -SELSFTFNLQDLQKCNVFIVTVPTPIDEHKQPDLTPLVKASESIGKVLKKGDIVIYEST 118
Query: 120 VPPGTTER-MAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASI 178
V PG TE +LE+ +GL+ EDF+ ++PER+ PG + ++ G + + +
Sbjct: 119 VYPGATEEDCVPVLEKFSGLRFNEDFFAGYSPERINPGDKEHRVSSIKKVTSGSTPEIAE 178
Query: 179 LAEKLYRSFVK-GRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
L + LYR + G ++ AE K++ENT RD+NIAL NE A + ++ G++ ++
Sbjct: 179 LVDSLYREIITAGTHKASSIKVAEAAKVIENTQRDLNIALINELAIIFNRMGIDTEAVLK 238
Query: 238 LANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLG----LIRKARKINESMPRFAAK 293
A T RPG+ VGGHC+ DPY L + + +G +I R++N+ M +
Sbjct: 239 AAGTKWNFMPFRPGL-VGGHCIGVDPY-YLTHKAQSIGYHPEIILAGRRLNDGMGAYVVS 296
Query: 294 LLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNG 353
L +A+ + + A VL++GL +K + D+RN+ ++ ++ + + +V +DP+V+
Sbjct: 297 QLVKAMLKRRIHVDGARVLLMGLTFKENCPDLRNTKVVDIVRELAEYNIQVDVFDPWVSA 356
Query: 354 THTILEEAVKGV--------DAIIIATDHSMFREIEWDKLGNLMR-NKIIIDGRNLVKE 403
+ E + V D II+A HS F+ + + + L + ++ D + L+ E
Sbjct: 357 EDAMHEYGITPVGTPSHGAYDGIILAVAHSEFKNMGAENIRKLGKAEHVLYDLKYLLDE 415
>pir||C82713 polysaccharide biosynthetic protein XF1183 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9106151|gb|AAF83993.1|AE003952_4 (AE003952)
polysaccharide biosynthetic protein [Xylella fastidiosa]
Length = 433
Score = 201 bits (505), Expect = 2e-50
Identities = 143/392 (36%), Positives = 206/392 (52%), Gaps = 22/392 (5%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
RIAV+GLGY+GLP A+ F +G+DI V+++ G H + EI L E+ +
Sbjct: 16 RIAVVGLGYVGLPLAVAFGRQ-RPTLGFDIDICRVQQLCAG--HDITCEI--ELEELQAA 70
Query: 62 GKLRATSDYNDLKGADAFIICVQTPLSNGV-PDLTYLESAIKTIAKVIEKEALVVIESTV 120
LR +SD +L FII V TP+ PDL L SA +A V++ LV+ ESTV
Sbjct: 71 RHLRYSSDPRELSDCQIFIITVPTPIDVAEQPDLGPLRSASMLVASVLKPGDLVIYESTV 130
Query: 121 PPGTTERMA-KLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASIL 179
PGTTE + LLE +GL DF+ ++PER+ PG + L +II G + + +
Sbjct: 131 YPGTTEEVCVPLLEVGSGLCFNVDFHCGYSPERINPGDRKRRLQDICKIISGSTPDITAV 190
Query: 180 AEKLYRSF-VKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIEL 238
+ LY V G + AE K++EN RDVNIAL NE A + ++ G++ + +E
Sbjct: 191 VDALYSQIIVAGTWCAPSIRVAEAAKVVENIQRDVNIALVNELALIFNRLGIDTLDVLEA 250
Query: 239 ANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLG----LIRKARKINESMPRFAAKL 294
A T RPG+ VGGHC+ DPY LL + E +G LI AR++N +
Sbjct: 251 AETKWNFLPFRPGL-VGGHCIGVDPYYLL-HKSESVGYYPDLIHTARRVNSRVSWHVVDR 308
Query: 295 LFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGT 354
+ LGE +V AVVLVLG+ +K D D+RNS AL+ +++ +V DP +
Sbjct: 309 VVALLGELSVPMTRAVVLVLGVTFKEDCPDLRNSRALDLVRMFRTLGAQVDVCDPCADPQ 368
Query: 355 HTILEEAVK--------GVDAIIIATDHSMFR 378
+ EAV DAI++A H+ +R
Sbjct: 369 QALEHEAVTLCTEPKAGAYDAIVLAVAHAQYR 400
>sp|O05973|UDG_RICPR UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|7431391|pir||E71638 UDP-glucose
6-dehydrogenase (udg) RP779 - Rickettsia prowazekii
>gi|2073510|emb|CAA72478.1| (Y11785) UDP-glucose
dehydrogenase [Rickettsia prowazekii]
>gi|3861306|emb|CAA15205.1| (AJ235273) UDP-GLUCOSE
6-DEHYDROGENASE (udg) [Rickettsia prowazekii]
Length = 434
Score = 199 bits (502), Expect = 4e-50
Identities = 144/428 (33%), Positives = 216/428 (49%), Gaps = 40/428 (9%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M I IG GY+GL + I+ GH+V D + K+N+ I I E ++ E L+ +
Sbjct: 1 MNITFIGSGYVGLVSGIIMGYLGHNVTCLDNDDVKISKLNKKILPIYEAKLDEYLKHALE 60
Query: 61 KGKLRATSDY-NDLKGADAFIICVQTPLSN-GVPDLTYLESAIKTIAKVIEKEALVVIES 118
+L+ T+ Y N+ + DA I V TP G DL Y+ A+ ++K I K+ L+VI+S
Sbjct: 61 SDRLKFTNIYSNEFRNFDAIFITVGTPSKELGEADLKYVYDAVDKVSKHINKDCLIVIKS 120
Query: 119 TVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAS- 177
TVPPG+ + L+ +G F VA PE + G ++ +Y RI+ GV+ K S
Sbjct: 121 TVPPGSCNNIIAYLKA-----KGFSFNVASNPEFLREGSAVEDFLYPDRIVVGVNNKESE 175
Query: 178 ILAEKLYRSFVK--GRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEA 235
L K+Y ++ + +T T+E++K + N+F IA NE A L K G N+ +
Sbjct: 176 ALLRKIYAPLIEQGAKFLVTNLVTSELIKYVSNSFLATKIAFINEMADLCEKIGANIKDL 235
Query: 236 IELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDE----DLGLIRKARKINESMP- 288
+ R+ G G GG C PKD L L N+ E D +++ K N+ P
Sbjct: 236 SQGVGLDQRIGRNFLNAGPGFGGSCFPKD-ILALNNLVENHKIDCKILKSVIKSNKLRPS 294
Query: 289 RFAAKLLFEALGEANVDPGDAV---VLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVR 345
AK+ A + GD + +LGL YK TDDVR SPA+E I I+ V+
Sbjct: 295 NMVAKI-------ATLLDGDLKGRNIAILGLTYKAGTDDVRASPAIEIITILLNKDVYVK 347
Query: 346 TYDPY------VNGTHTIL------EEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKI 393
+DP N H L EA K VD I+IAT+ S F+E+ W ++ NL+++ +
Sbjct: 348 AFDPIGLENAKKNLEHKNLLYFASAVEACKSVDIIVIATEWSEFKELNWQEIYNLVKSPM 407
Query: 394 IIDGRNLV 401
IID RN++
Sbjct: 408 IIDLRNIL 415
>gb|AAD40718.1|AF048749_14 (AF048749) putative UDP-glucose-6 dehydrogenase [Bacteroides
fragilis]
Length = 425
Score = 196 bits (494), Expect = 3e-49
Identities = 120/398 (30%), Positives = 210/398 (52%), Gaps = 23/398 (5%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
++IAVIGLGY+GLP A +F S+ ++ IG+D+ + V+ +N G H + E+ + L
Sbjct: 4 LKIAVIGLGYVGLPLARLF-STKYECIGFDLNQSRVDALNSG--HDMTLEVSDDLLRKAL 60
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIEST 119
+ + TS+ +++ + +++ V TP+ N PDLT L A T+ KVI K +VV EST
Sbjct: 61 ENGFKCTSNIDEISNCNFYVVAVPTPVDLNNRPDLTPLIGASTTVGKVISKGDIVVYEST 120
Query: 120 VPPGTTERMA-KLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASI 178
V PG TE ++EE++GL DFY ++PER+ PG + ++ G + + +
Sbjct: 121 VYPGVTEEECLPVVEEVSGLTYNVDFYAGYSPERINPGDKEHTVEKIKKVTSGSTPEIAD 180
Query: 179 LAEKLYRS-FVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
+ + +Y S V G + AE K++EN+ RDVNIA NE + + + G++ + IE
Sbjct: 181 IVDSVYNSVLVNGTHKAPSIKVAEASKIIENSQRDVNIAFMNELSKIFNAMGIDTNDVIE 240
Query: 238 LANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRK----ARKINESMPRFAAK 293
A++ +PG+ VGGHC+ DPY L+ + G++ + AR++N+ M + A
Sbjct: 241 AASSKWNFIKLKPGL-VGGHCISVDPYYLIQKA-QVYGVLPRIMSAARRLNDGMGDYVAN 298
Query: 294 LLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNG 353
+ + + + D+ +L+LG +K D D+RN+ ++ + + ++ YD + N
Sbjct: 299 QVIRLMNKKGILVKDSKILLLGFTFKEDCPDIRNTKVIDIYSTLHEYTSDITVYDAWANS 358
Query: 354 THTI-----------LEEAVKGVDAIIIATDHSMFREI 380
L+ V DA+++ H FR +
Sbjct: 359 AKVAHEYGISILTAGLDNLVGQFDAVVLCVGHKEFRHM 396
>sp|Q04972|VIPA_SALTI VI POLYSACCHARIDE BIOSYNTHESIS PROTEIN VIPA/TVIB
>gi|1361287|pir||B36892 Vi polysaccharide biosynthetic
protein VipA - Salmonella typhi
>gi|475033|dbj|BAA03192.1| (D14156) WcdA protein
[Salmonella typhi] >gi|581779|emb|CAA47991.1| (X67785)
wcdA; ORF2 in citation [1] [Salmonella typhi]
Length = 425
Score = 196 bits (492), Expect = 5e-49
Identities = 125/410 (30%), Positives = 222/410 (53%), Gaps = 22/410 (5%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
++IA+IGLGY+GLP A+ F S V+G+D+ + + ++ G+ +E E LRE
Sbjct: 7 VKIAIIGLGYVGLPLAVEFGKS-RQVVGFDVNKKRILELKNGVDVNLETT-EEELREA-- 62
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSN-GVPDLTYLESAIKTIAKVIEKEALVVIEST 119
L+ TS+ +K + +II V TP++ PDLT L A +T+ V+ + +VV EST
Sbjct: 63 -RYLKFTSEIEKIKECNFYIITVPTPINTYKQPDLTPLIKASETVGTVLNRGDIVVYEST 121
Query: 120 VPPGTTER-MAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASI 178
V PG TE +L ++G+ +DFYV ++PER+ PG L +I G + + +
Sbjct: 122 VYPGCTEEECVPILARMSGMTFNQDFYVGYSPERINPGDKKHRLTNIKKITSGSTAQIAE 181
Query: 179 LAEKLYRSFVK-GRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
L +++Y+ + G + AE K++ENT RD+NIAL NE A + ++ ++ +
Sbjct: 182 LIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLNIALVNELAIIFNRLNIDTEAVLR 241
Query: 238 LANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLG----LIRKARKINESMPRFAAK 293
A + RPG+ VGGHC+ DPY L + + +G +I R++N++M + ++
Sbjct: 242 AAGSKWNFLPFRPGL-VGGHCIGVDPYYL-THKSQGIGYYPEIILAGRRLNDNMGNYVSE 299
Query: 294 LLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVN- 352
L +A+ + ++ + VL+LG +K + D+RN+ ++ +K + K +V +DP+V+
Sbjct: 300 QLIKAMIKKGINVEGSSVLILGFTFKENCPDIRNTRIIDVVKELGKYSCKVDIFDPWVDA 359
Query: 353 -------GTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIII 395
G + E DAII+A H F+++ + + ++K ++
Sbjct: 360 EEVRREYGIIPVSEVKSSHYDAIIVAVGHQQFKQMGSEDIRGFGKDKHVL 409
>pir||H70301 nucleotide sugar dehydrogenase - Aquifex aeolicus
>gi|2982765|gb|AAC06391.1| (AE000669) nucleotide sugar
dehydrogenase [Aquifex aeolicus]
Length = 437
Score = 193 bits (486), Expect = 3e-48
Identities = 142/442 (32%), Positives = 235/442 (53%), Gaps = 33/442 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+++VIG GY+GL TA F+ GH+V+ + + VE + RG + I EP + E LRE ++
Sbjct: 1 MKLSVIGGGYVGLVTAACFSHLGHEVLVVEKIPEKVELLRRGKSPIYEPGLEELLREGIN 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIES 118
+G+L T+D + ++ ++ ICV TP + +G DL+ +E + AK ++ L+V +S
Sbjct: 61 EGRLSFTTDIKEGIEFSEVIFICVGTPSNPDGSADLSQVEEVARFTAKYMDSYKLLVNKS 120
Query: 119 TVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV-SEKAS 177
TVP GT ++ + + KE E F VA PE + G K+ + RI+ GV SE+A
Sbjct: 121 TVPVGTQRKVKRTVRLYLKNKELE-FDVASNPEFLREGHAVKDFLEPDRIVVGVESERAK 179
Query: 178 ILAEKLYRSFV-KG-RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEA 235
+ ++Y+ KG I +T TAE++K NTF I+ N + L K G NV E
Sbjct: 180 EVLLEIYKPITDKGFPILITNPPTAEIIKYASNTFLATKISFINMISDLCEKVGANVEEV 239
Query: 236 IELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDE---DLGLIRKARKINESMPRF 290
+ R+ + R G+G GG CLPKD + ++E D +++ A INES
Sbjct: 240 AQGMGYDKRIGKEFLRAGLGWGGSCLPKDTKAFIRILEELGVDATILKGALGINES---- 295
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPY 350
L + L +A + + GL++K +TDD+R +P+L+ ++ + ++ ++R YDP
Sbjct: 296 RVDRLLQKLKDALWILKGKTIAIWGLSFKPNTDDIREAPSLKVVERLLREGAKIRAYDPK 355
Query: 351 V--NGTHTILE-----------EAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDG 397
N +E +AV+G +A++I T+ F+ +++ LM IIIDG
Sbjct: 356 ATENFKRVFIEGEDLRYFDDKYKAVEGAEALLILTEWDEFKRANLERVKRLMELPIIIDG 415
Query: 398 RNLVKEPPK----GFIFKGIGR 415
RN + +P + GF + +GR
Sbjct: 416 RN-IYDPQEVRNLGFEYYSMGR 436
>sp|P39861|CAPL_STAAU CAPL PROTEIN >gi|506708|gb|AAA64651.1| (U10927) CapL
[Staphylococcus aureus]
Length = 424
Score = 191 bits (480), Expect = 1e-47
Identities = 129/413 (31%), Positives = 211/413 (50%), Gaps = 21/413 (5%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
IAV+GLGY+GLP A+ F + H VIG+DI ++++ E +
Sbjct: 5 IAVVGLGYVGLPVAVTFGNK-HKVIGFDINESRIKELKNNY-----DRTNEVTENKLKNT 58
Query: 63 KLRATSDYNDLKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIESTVP 121
+ TS+ DLK AD II V TP+ + PDL L A +T+ KVI + +VV ESTV
Sbjct: 59 NIEYTSNAEDLKKADFIIIAVPTPIDKHNKPDLLPLLKASETVGKVITPDTIVVYESTVY 118
Query: 122 PGTTER-MAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILA 180
PG TE +LE+ +GL G+DF+V ++PER+ PG ++++ G + + +
Sbjct: 119 PGATEEECVPVLEKYSGLVCGKDFFVGYSPERINPGDKVHTFETITKVVSGQTLEVLEIV 178
Query: 181 EKLYRSFVKGRIFLTTAT-TAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELA 239
+Y S V + ++ AE K++ENT RDVNIAL NE A + K ++ E ++ +
Sbjct: 179 ADVYSSVVTAGVHKASSIKVAEAAKVIENTQRDVNIALMNELAIIFDKLDIDTNEVLKAS 238
Query: 240 NTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDE---DLGLIRKARKINESMPRFAAKLLF 296
T +PG+ VGGHC+ DPY L E +I R+IN++M ++ A +
Sbjct: 239 GTKWNFLNFKPGL-VGGHCIGVDPYYLTHKAQEVGHHPEVILAGRRINDNMAKYIASNVI 297
Query: 297 EALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEK--------DVKEVRTYD 348
+ L + ++ A V VLGL +K + D+RN+ + I+ +++ DV+ +
Sbjct: 298 KELLKQGLEVQGATVNVLGLTFKENCPDLRNTKVIHIIEELKEYGLNVTVNDVEADKNEA 357
Query: 349 PYVNGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLV 401
G I + +K VD ++ A H + E + D + + I+ D + ++
Sbjct: 358 KKFFGLDLIDTKELKMVDVVLFAVPHKDYMENKKDYINLVKDCGIVFDIKGII 410
>pir||H75095 udp-glucose dehydrogenase (ugd) PAB0770 - Pyrococcus abyssi
(strain Orsay) >gi|5458581|emb|CAB50069.1| (AJ248286)
UDP-glucose dehydrogenase (ugd) [Pyrococcus abyssi]
Length = 427
Score = 189 bits (476), Expect = 4e-47
Identities = 145/443 (32%), Positives = 223/443 (49%), Gaps = 48/443 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M +++IG GY+GL T + F G+ VI D+ V +N I E + E ++E
Sbjct: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
Query: 61 KGKLRATSDYND-LKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKE---ALVV 115
KGK AT++Y + + +D I V TP +G DLTY+++A K I K ++++ +VV
Sbjct: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
Query: 116 IESTVPPGTTERMAK-LLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV-S 173
++STV PGTTE + + +LE+ +G K +DF +A PE + G K+ + RI+ GV
Sbjct: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
Query: 174 EKASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
E+ + EKLY F ++F T TAEM+K N F I+ ANE + K G++ +
Sbjct: 179 ERTKKVLEKLYEPFNAPKLF-TDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVD---EDLGLIRKARKINESMP 288
+ E R+ H R GIG GG C PKD L+ + ED +++ ++NE P
Sbjct: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
Query: 289 RFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYD 348
L E L + + D V VLGLA+K +TDDVR + A IK + ++ +V YD
Sbjct: 298 ----LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYD 353
Query: 349 P------------------YVNGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMR 390
P Y N EE ++ VD I+I T+ F +++
Sbjct: 354 PKAMENFKRFYPDVGRQISYANSA----EEVLREVDVILILTEWRDFESLDYS------- 402
Query: 391 NKIIIDGRNLVKEPPKGFIFKGI 413
KI+IDGR + I++G+
Sbjct: 403 GKIVIDGRRVRSAEKTAKIYEGV 425
>pir||T44509 Vi polysaccharide biosynthetic protein [imported] - Plesiomonas
shigelloides >gi|6009648|dbj|BAA85006.1| (AB025970)
ORF1P [Plesiomonas shigelloides]
>gi|10442655|gb|AAG17408.1|AF285970_2 (AF285970) WbgT
[Plesiomonas shigelloides]
Length = 437
Score = 189 bits (476), Expect = 4e-47
Identities = 126/393 (32%), Positives = 206/393 (52%), Gaps = 20/393 (5%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
+I +IGLGY+GLP A+ F IG+DI + ++++ G +E E L
Sbjct: 20 KIGIIGLGYVGLPLAVEFGKKV-TTIGFDINKSRIDELRNGHDSTLECSNLELLEAT--- 75
Query: 62 GKLRATSDYNDLKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
KL + LK + FI+ V TP+ + PDLT L A +T+ K+I+K +++ ESTV
Sbjct: 76 -KLTYACSLDALKECNVFIVTVPTPIDKHKQPDLTPLIKASETLGKIIKKGDVIIYESTV 134
Query: 121 PPGTTER-MAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASIL 179
PG TE ++E+++GLK DF+ ++PER+ PG + ++ G + +
Sbjct: 135 YPGATEEDCIPVVEKVSGLKFNIDFFAGYSPERINPGDKEHRVTNILKVTSGSTPDVAEY 194
Query: 180 AEKLYRSFVK-GRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIEL 238
++LY+ + G ++ AE K++ENT RDVNIAL NE + + +K G++ E +E
Sbjct: 195 VDQLYKLIITVGTHKASSIKVAEAAKVIENTQRDVNIALINELSIIFNKLGIDTLEVLEA 254
Query: 239 ANTHPRVKIHRPGIGVGGHCLPKDPYLL---LANVDEDLGLIRKARKINESMPRFAAKLL 295
A T RPG+ VGGHC+ DPY L +V +I R++N+SM ++ L
Sbjct: 255 AGTKWNFLPFRPGL-VGGHCIGVDPYYLTHKAQSVGYHPEMILAGRRLNDSMGQYVVSQL 313
Query: 296 FEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVN--- 352
+ + + + A VLV+GL +K + D+RN+ ++ I +++ + DP+ +
Sbjct: 314 VKKMLKQRIQVEGANVLVMGLTFKENCPDLRNTKVIDIISELKEYNINIDIIDPWCSTDE 373
Query: 353 -----GTHTILEEAVKGVDAIIIATDHSMFREI 380
G + V DAIIIA H+ FRE+
Sbjct: 374 AQHEYGLTLCEDPKVNHYDAIIIAVAHNEFREM 406
>pir||T44520 lipopolysaccharide biosynthesis protein [imported] - Shigella
sonnei >gi|6009797|dbj|BAA85071.1| (AB028135) ORF1S
[Shigella sonnei] >gi|10442666|gb|AAG17418.1|AF285971_2
(AF285971) WbgT [Shigella sonnei]
Length = 437
Score = 189 bits (476), Expect = 4e-47
Identities = 126/393 (32%), Positives = 206/393 (52%), Gaps = 20/393 (5%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
+I +IGLGY+GLP A+ F IG+DI + ++++ G +E E L
Sbjct: 20 KIGIIGLGYVGLPLAVEFGKKV-TTIGFDINKSRIDELRNGHDSTLECSNLELLEAT--- 75
Query: 62 GKLRATSDYNDLKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
KL + LK + FI+ V TP+ + PDLT L A +T+ K+I+K +++ ESTV
Sbjct: 76 -KLTYACSLDALKECNVFIVTVPTPIDKHKQPDLTPLIKASETLGKIIKKGDVIIYESTV 134
Query: 121 PPGTTER-MAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASIL 179
PG TE ++E+++GLK DF+ ++PER+ PG + ++ G + +
Sbjct: 135 YPGATEEDCIPVVEKVSGLKFNIDFFAGYSPERINPGDKEHRVTNILKVTSGSTPDVAEY 194
Query: 180 AEKLYRSFVK-GRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIEL 238
++LY+ + G ++ AE K++ENT RDVNIAL NE + + +K G++ E +E
Sbjct: 195 VDQLYKLIITVGTHKASSIKVAEAAKVIENTQRDVNIALINELSIIFNKLGIDTLEVLEA 254
Query: 239 ANTHPRVKIHRPGIGVGGHCLPKDPYLL---LANVDEDLGLIRKARKINESMPRFAAKLL 295
A T RPG+ VGGHC+ DPY L +V +I R++N+SM ++ L
Sbjct: 255 AGTKWNFLPFRPGL-VGGHCIGVDPYYLTHKAQSVGYHPEMILAGRRLNDSMGQYVVSQL 313
Query: 296 FEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVN--- 352
+ + + + A VLV+GL +K + D+RN+ ++ I +++ + DP+ +
Sbjct: 314 VKKMLKQRIQVEGANVLVMGLTFKENCPDLRNTKVIDIISELKEYNINIDIIDPWCSTDE 373
Query: 353 -----GTHTILEEAVKGVDAIIIATDHSMFREI 380
G + V DAIIIA H+ FRE+
Sbjct: 374 AQHEYGLTLCEDPKVNHYDAIIIAVAHNEFREM 406
>gb|AAK41109.1| UDP-glucose 6-dehydrogenase (ugd) [Sulfolobus solfataricus]
Length = 409
Score = 189 bits (475), Expect = 5e-47
Identities = 134/416 (32%), Positives = 212/416 (50%), Gaps = 41/416 (9%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRI V+GLG +GL T + A GH+V+G DI ++ V+ + + I EP + E L + +
Sbjct: 1 MRIGVVGLGVVGLVTGAVLADQGHEVVGVDIDQNKVKGLQCNRSPIYEPGLDELLLK--N 58
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
K + T+DY+ LK D I V TP G + Y+ A KT+ ++++A+VV++STV
Sbjct: 59 KNRFLFTTDYSALKDVDIVFITVATPTVEGKNYIGYVLDAAKTMKPYLKRDAIVVVKSTV 118
Query: 121 PPGTTERMAKLLE-ELTG----LKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEK 175
PGT+ ++ +++E E+ LKEG P+R+ +IG S+
Sbjct: 119 VPGTSRKVKQIVEREVVANPEFLKEGSAVIDTIKPDRI--------------VIGSDSKA 164
Query: 176 ASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKY-GVNVYE 234
A + E L+ SF K + T+ AEM+K N+F I+ NE A L +V
Sbjct: 165 AGDVIENLW-SFTKTVVLRTSIEEAEMIKYAANSFLATKISFINEIANLCEVIPNCDVNT 223
Query: 235 AIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLA---NVDEDLGLIRKARKINESMPR 289
+ R+ + G+G GG C PKD + + E+L ++ A K+NE PR
Sbjct: 224 IAKAIGLDKRIAPYFLNAGLGYGGSCFPKDTLAFASFARELGEELKIVEAAIKVNEERPR 283
Query: 290 FAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
A K++ E LGE + +LG+A+K +TDD R S AL+ K++ V YDP
Sbjct: 284 RAVKIMEELLGELK----GKTICILGIAFKPNTDDTRESVALKIAKLLVDIGANVIAYDP 339
Query: 350 YVNGTHTIL----EEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLV 401
+ + EE VK D +IIAT+ FR IE +++++K ++DGR ++
Sbjct: 340 KAKTSLVEMVSSKEECVKRSDGVIIATEWDEFRGIE-----HMLKDKAVLDGRRVL 390
>emb|CAB57493.1| (Y18930) udp-glucose dehydrogenase [Sulfolobus solfataricus]
Length = 409
Score = 189 bits (475), Expect = 5e-47
Identities = 134/416 (32%), Positives = 212/416 (50%), Gaps = 41/416 (9%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRI V+GLG +GL T + A GH+V+G DI ++ V+ + + I EP + E L + +
Sbjct: 1 MRIGVVGLGVVGLVTGAVLADQGHEVVGVDIDQNKVKGLQCNRSPIYEPGLDELLLK--N 58
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
K + T+DY+ LK D I V TP G + Y+ A KT+ ++++A+VV++STV
Sbjct: 59 KNRFLFTTDYSALKDVDIVFITVATPTVEGKNYIGYVLDAAKTMKPYLKRDAIVVVKSTV 118
Query: 121 PPGTTERMAKLLE-ELTG----LKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEK 175
PGT+ ++ +++E E+ LKEG P+R+ +IG S+
Sbjct: 119 VPGTSRKVKQIVEREVVANPEFLKEGSAVIDTIKPDRI--------------VIGSDSKA 164
Query: 176 ASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKY-GVNVYE 234
A + E L+ SF K + T+ AEM+K N+F I+ NE A L +V
Sbjct: 165 AGDVIENLW-SFTKTVVLRTSIEEAEMIKYAANSFLATKISFINEIANLCEVIPNCDVNT 223
Query: 235 AIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLA---NVDEDLGLIRKARKINESMPR 289
+ R+ + G+G GG C PKD + + E+L ++ A K+NE PR
Sbjct: 224 IAKAIGLDKRIAPYFLNAGLGYGGSCFPKDTLAFASFARELGEELKIVEAAIKVNEERPR 283
Query: 290 FAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
A K++ E LGE + +LG+A+K +TDD R S AL+ K++ V YDP
Sbjct: 284 RAVKIMEELLGELK----GKTICILGIAFKPNTDDTRESVALKIAKLLVDIGANVIAYDP 339
Query: 350 YVNGTHTIL----EEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLV 401
+ + EE VK D +IIAT+ FR IE +++++K ++DGR ++
Sbjct: 340 KAKTSLVEMVSSKEECVKRSDGVIIATEWDEFRGIE-----HMLKDKAVLDGRRVL 390
>pir||A70067 NDP-sugar dehydrogenase homolog ywqF - Bacillus subtilis
>gi|1894744|emb|CAB07444.1| (Z92952) product similar to
Pseudomonas aeruginosa GDP-mannose 6-dehydrogenase
protein [Bacillus subtilis] >gi|2636148|emb|CAB15640.1|
(Z99122) similar to NDP-sugar dehydrogenase [Bacillus
subtilis]
Length = 440
Score = 187 bits (470), Expect = 2e-46
Identities = 135/418 (32%), Positives = 208/418 (49%), Gaps = 26/418 (6%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M I VIG GY+GL T + + GH V DI ++++ +GI+ I EP + E +R+ +
Sbjct: 1 MNITVIGTGYVGLVTGVSLSEIGHHVTCIDIDAHKIDEMRKGISPIFEPGLEELMRKNTA 60
Query: 61 KGKLRATSDY-NDLKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
G+L + Y L AD I V TP S+G +L + A K IAK ++++ +VV +S
Sbjct: 61 DGRLNFETSYEKGLAQADIIFIAVGTPQKSDGHANLEQITDAAKRIAKHVKRDTVVVTKS 120
Query: 119 TVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEKAS 177
TVP GT + + L+ E L E VA PE + G + + RI IG EK +
Sbjct: 121 TVPVGTNDLINGLITE--HLAEPVSISVASNPEFLREGSAIYDTFHGDRIVIGTADEKTA 178
Query: 178 ILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
E+L+R F + I+ T +AEM+K N F I+ NE + + K G ++
Sbjct: 179 NTLEELFRPF-QIPIYQTDIRSAEMIKYASNAFLATKISFINEISNICEKVGADIEAVAY 237
Query: 238 LANTHPRV--KIHRPGIGVGGHCLPKDPYLLL---ANVDEDLGLIRKARKINESMPRFAA 292
R+ + + GIG GG C PKD L+ NV+ D L++ K+N + A
Sbjct: 238 GMGQDKRIGSQFLKAGIGYGGSCFPKDTNALVQIAGNVEHDFELLKSVIKVNNNQ---QA 294
Query: 293 KLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYV- 351
L+ +AL G + L LGL++K +TDD+R +P++ + +R YDP
Sbjct: 295 MLVDKALNRLGGVTGKTIAL-LGLSFKPNTDDMREAPSIVIADRLAALDARIRAYDPIAV 353
Query: 352 -NGTHTI---------LEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRN 399
+ H + +EEAVKG DA++I TD + ++ +LM +I DGRN
Sbjct: 354 SHAKHVLPQAVEYKETIEEAVKGSDAVMILTDWADIKQFPLAAYQDLMETPLIFDGRN 411
>emb|CAC05895.1| (AL391754) putative dehydrogenase [Streptomyces coelicolor]
Length = 443
Score = 187 bits (470), Expect = 2e-46
Identities = 132/392 (33%), Positives = 189/392 (47%), Gaps = 14/392 (3%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
+AV+GLGY+GLPTA+ +G VIG D + + + RG ++ P +L +
Sbjct: 17 VAVVGLGYVGLPTALALCDAGATVIGVDSSPERLRDIARGAVDLL-PLHHAQLACASAGD 75
Query: 63 KLRATSDYNDLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIESTVP 121
+ R T D ++ ADA +ICV TP+ + PDL L +A ++ + L+V+ ST
Sbjct: 76 RFRLTPDATAVRDADAVVICVPTPVDARRRPDLAALSAACASVVEHAVPGQLIVLTSTSY 135
Query: 122 PGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILAE 181
GTT + GL ED YVA APER+ PG R++GG ++S A
Sbjct: 136 VGTTRDLLVEPLRARGLTVDEDVYVAFAPERIDPGNERHTPERTPRLVGGAGPRSSRAAA 195
Query: 182 KLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELANT 241
L + TAEM KL ENT+R VNIALANE A H G+ IE A T
Sbjct: 196 DLLAPTASAVRTVPDPETAEMAKLWENTYRAVNIALANELADACHSLGLAPAPVIEAAAT 255
Query: 242 HP-RVKIHRPGIGVGGHCLPKDPYLL---LANVDEDLGLIRKARKINESMPRFAAKLLFE 297
P PG GVGGHC+P DP+ L L V + L+ A N P + +
Sbjct: 256 KPYGFMPFYPGPGVGGHCIPCDPHYLLWQLGKVRQQAPLVATALAANSRRPARITERALD 315
Query: 298 ALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYV------ 351
L ++ V A VL++G+AYK DVR SPALE + + + V DP V
Sbjct: 316 LLADSAVPAHGARVLLIGVAYKEGVADVRESPALEILAGLAEAGAHVAYCDPLVPSLRVG 375
Query: 352 -NGTHTILEEAVKGVDAIIIATDHSMFREIEW 382
+ H + + + D +++ T H + ++ W
Sbjct: 376 ADALHHLPDPHTRPWDLVVLNTVHPV-HDLTW 406
>pir||F69727 biosynthesis of teichuronic acid (UDP-glucose 6-dehydrogenase) tuaD
- Bacillus subtilis >gi|2454559|gb|AAB94865.1|
(AF015609) UDP-glucose dehydrogenase [Bacillus subtilis]
>gi|2636084|emb|CAB15575.1| (Z99122) UDP-glucose
6-dehydrogenase [Bacillus subtilis]
Length = 461
Score = 184 bits (463), Expect = 1e-45
Identities = 134/436 (30%), Positives = 217/436 (49%), Gaps = 29/436 (6%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
+IAVIG GY+GL + FA G+ V+ DI + + G+ I EP + + + + V
Sbjct: 3 KIAVIGTGYVGLVSGTCFAEIGNKVVCCDIDESKIRSLKNGVIPIYEPGLADLVEKNVLD 62
Query: 62 GKLRATSDY-NDLKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIEST 119
+L T+D + ++ +D I V TP+S G DLTY+++A KTI + + ++V +ST
Sbjct: 63 QRLTFTNDIPSAIRASDIIYIAVGTPMSKTGEADLTYVKAAAKTIGEHLNGYKVIVNKST 122
Query: 120 VPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSR-IIGGVSEKASI 178
VP GT + + ++++ + K F V PE + G + + R +IG S KA+
Sbjct: 123 VPVGTGKLVQSIVQKAS--KGRYSFDVVSNPEFLREGSAIHDTMNMERAVIGSTSHKAAA 180
Query: 179 LAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIEL 238
+ E+L++ F + T +AEM+K N F I+ N+ A + + G +V + +
Sbjct: 181 IIEELHQPF-HAPVIKTNLESAEMIKYAANAFLATKISFINDIANICERVGADVSKVADG 239
Query: 239 ANTHPRV--KIHRPGIGVGGHCLPKDPYLLL---ANVDEDLGLIRKARKINESMPRFAAK 293
R+ K + GIG GG C PKD LL + LI + NE
Sbjct: 240 VGLDSRIGRKFLKAGIGFGGSCFPKDTTALLQIAKSAGYPFKLIEAVIETNEKQRVHIVD 299
Query: 294 LLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPY-VN 352
L +G + VLGLA+K +T+DVR++PAL+ I ++++ V+ YDP +
Sbjct: 300 KLLTVMGSVK----GRTISVLGLAFKPNTNDVRSAPALDIIPMLQQLGAHVKAYDPIAIP 355
Query: 353 GTHTILEE----------AVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLV- 401
IL E A++ DA +I TD +E+E K+ L++ +IIDGRNL
Sbjct: 356 EASAILGEQVEYYTDVYAAMEDTDACLILTDWPEVKEMELVKVKTLLKQPVIIDGRNLFS 415
Query: 402 --KEPPKGFIFKGIGR 415
+ G+I+ IGR
Sbjct: 416 LEEMQAAGYIYHSIGR 431
>gb|AAA84869.1| (U34305) ORF1; Method: conceptual translation supplied by author
[Shigella sonnei]
Length = 416
Score = 182 bits (458), Expect = 5e-45
Identities = 121/392 (30%), Positives = 202/392 (50%), Gaps = 19/392 (4%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
+I +IGLGY+GLP A+ F IG+DI + ++++ G +E E L
Sbjct: 9 KIGIIGLGYVGLPLAVEFGKKV-TTIGFDINKSRIDELRNGHDSTLECSNLELLEAT--- 64
Query: 62 GKLRATSDYNDLKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
KL + LK + FI+ V P+ + PDLT L A +T+ K+I+K +++ ESTV
Sbjct: 65 -KLTYACSLDALKECNVFIVTVPAPIDKHKQPDLTPLIKASETLGKIIKKGDVIIYESTV 123
Query: 121 PPGTTER-MAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASIL 179
PG TE ++E+++GLK DF+ ++PER+ PG + ++ G + +
Sbjct: 124 YPGATEEDCIPVVEKVSGLKFNIDFFAGYSPERINPGDKEHRVTNILKVASGSTPDVAEY 183
Query: 180 AEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELA 239
++LY+ + ++ E ++ NT RDVNIAL NE + + +K G++ E +E A
Sbjct: 184 VDQLYKLIITVGTHKASSIKVERLQSNVNTQRDVNIALINELSIIFNKLGIDTLEVLEAA 243
Query: 240 NTHPRVKIHRPGIGVGGHCLPKDPYLL---LANVDEDLGLIRKARKINESMPRFAAKLLF 296
T + RPG+ VGGHC+ DPY L +V +I R++N+SM ++ L
Sbjct: 244 GTKWNLLPFRPGL-VGGHCIGVDPYYLTHKAQSVGYHPEMILAGRRLNDSMGQYVVSQLV 302
Query: 297 EALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVN---- 352
+ + + + A VLV+GL +K + D+RN+ ++ I +++ + DP+ +
Sbjct: 303 KKMLKQRIQVEGANVLVMGLTFKENCPDLRNTKVIDIISELKEYNINIDIIDPWCSTDEA 362
Query: 353 ----GTHTILEEAVKGVDAIIIATDHSMFREI 380
G + V DAIIIA H+ FRE+
Sbjct: 363 QHEYGLTLCEDPKVNHYDAIIIAVAHNEFREM 394
>sp|O54068|UDG_RHIME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH)
Length = 437
Score = 178 bits (447), Expect = 1e-43
Identities = 128/443 (28%), Positives = 212/443 (46%), Gaps = 32/443 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I +IG GY+GL + + FA GHDV+ D + + +G I EP + + V+
Sbjct: 1 MKITMIGAGYVGLVSGVCFADFGHDVVCVDKDEGKISALKKGQIPIFEPGLDHLVASNVA 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTP--LSNGVPDLTYLESAIKTIAKVIEKEALVVIE 117
G+L T D + +D I V TP +G DL+Y+ +A + IA ++ +VV +
Sbjct: 61 SGRLNFTDDLKTAVAASDVVFIAVGTPSRRGDGHADLSYVYAAAREIAANLQGFTVVVTK 120
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV---SE 174
STVP GT + + +++ E D V PE + G ++ RI+ GV
Sbjct: 121 STVPVGTGDEVERIIRE---TNPAADVTVVSNPEFLREGAAIEDFKRPDRIVIGVDGSDG 177
Query: 175 KASILAEKLYRSFV--KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNV 232
+A + ++YR + + TT T+E++K N F + I NE A L K G NV
Sbjct: 178 RAREVMTEVYRPLYLNQSPLVFTTRRTSELIKYAGNAFLAMKITFINEIADLCEKVGANV 237
Query: 233 YEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANV---DEDLGLIRKARKINESM 287
+ R+ K G G GG C PKD L+ D + L+ +N++
Sbjct: 238 QDVARGIGLDGRIGSKFLHAGPGYGGSCFPKDTLALVKTAQDHDTPVRLVETTVAVNDNR 297
Query: 288 PRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTY 347
R + + A G D + + VLGL +K +TDD+R+SPA+ ++ ++ V Y
Sbjct: 298 KRAMGRKVIAAAGG---DIRGSKIAVLGLTFKPNTDDMRDSPAIAVVQALQDAGARVTGY 354
Query: 348 DPY-VNGTHTILE---------EAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDG 397
DP + ++E EA DA++I T+ + FR +++D+L + M+ +++D
Sbjct: 355 DPEGMENARKLIEGLDCARDPYEAAAEADALVIITEWNEFRALDFDRLKSTMKTPLLVDL 414
Query: 398 RNLVKE---PPKGFIFKGIGRGD 417
RN+ ++ GF + IGR D
Sbjct: 415 RNIYRKDEVAKHGFRYASIGRPD 437
>gb|AAC12870.1| (AF044332) UDP-ManNAc dehydrogenase; RffD [Pectobacterium
carotovorum subsp. atrosepticum]
Length = 287
Score = 176 bits (441), Expect = 5e-43
Identities = 96/258 (37%), Positives = 143/258 (55%), Gaps = 14/258 (5%)
Query: 140 EGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILAEKLYRSFVKGRIFLTTATT 199
E D +A+ PERV+PG++ EL+ N R+IGG++ S A +LY F++G +T + T
Sbjct: 15 ETADINIAYCPERVLPGQVVVELIKNDRVIGGMTPVCSARASELYNIFLEGECVVTNSRT 74
Query: 200 AEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELANTHPRVKIHRPGIGVGGHCL 259
AEM KL EN+FRDVNIA ANE + + + +NV+E I LAN HPRV I +PG GVGGHC+
Sbjct: 75 AEMCKLTENSFRDVNIAFANELSLICAEQNINVWELIRLANRHPRVNILQPGPGVGGHCI 134
Query: 260 PKDPYLLLANVDEDLGLIRKARKINESMPRFAAKLLFEA----LGEANVDPGDAVVLVLG 315
DP+ ++A + LI AR +N+ P + + A L + + + V G
Sbjct: 135 AVDPWFIVAQNPQQARLIHTARLVNDGKPLWVVDRVKAAVADYLAQTDKRASEVTVACFG 194
Query: 316 LAYKGDTDDVRNSPALEFIKIIEK-DVKEVRTYDPYVNGTHTIL---------EEAVKGV 365
LA+K D DD+R SPA+ +I + + +P V ++L A+K
Sbjct: 195 LAFKPDIDDLRESPAVGITSMIAQWNTGVTLVVEPNVKHLPSVLAGQVKLVDTSSALKEA 254
Query: 366 DAIIIATDHSMFREIEWD 383
D +++ DH F+ I D
Sbjct: 255 DVLVMLVDHRQFKAINPD 272
>pir||T46573 UDPglucose 6-dehydrogenase (EC 1.1.1.22) [validated] -
Sinorhizobium meliloti >gi|2959984|emb|CAA10918.1|
(AJ222661) UDP-glucose dehydrogenase [Sinorhizobium
meliloti]
Length = 437
Score = 175 bits (440), Expect = 7e-43
Identities = 127/443 (28%), Positives = 211/443 (46%), Gaps = 32/443 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I +IG GY+GL + + FA GHDV+ D + + +G I EP + + V+
Sbjct: 1 MKITMIGAGYVGLVSGVCFADFGHDVVCVDKDEGKISALKKGQIPIFEPGLDHLVASNVA 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTP--LSNGVPDLTYLESAIKTIAKVIEKEALVVIE 117
G+L T D + +D I V TP +G DL+Y+ +A + IA ++ +VV +
Sbjct: 61 SGRLNFTDDLKTAVAASDVVFIAVGTPSRRGDGHADLSYVYAAAREIASNLQGFTVVVTK 120
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV---SE 174
STVP GT + + +++ E D V PE + G ++ RI+ GV
Sbjct: 121 STVPVGTGDEVERIIRE---TNPAVDVTVVSNPEFLREGAAIEDFKRPDRIVIGVDGSDG 177
Query: 175 KASILAEKLYRSFV--KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNV 232
+A + ++YR + + TT T+E++K N F + I NE A L K G NV
Sbjct: 178 RAREVMTEVYRPLYLNQSPLVFTTRRTSELIKYAGNAFLAMKITFINEIADLCEKVGANV 237
Query: 233 YEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANV---DEDLGLIRKARKINESM 287
+ R+ K G G GG C PKD L+ D + L+ +N++
Sbjct: 238 QDVARGIGLDGRIGSKFLHAGPGYGGSCFPKDTLALVKTAQDHDTPVRLVETTVAVNDNR 297
Query: 288 PRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTY 347
R + + A G D + VLGL +K +TDD+R++PA+ ++ ++ V Y
Sbjct: 298 KRAMGRKVIAAAGG---DIRGSKYAVLGLTFKPNTDDMRDTPAIAVVQALQDAGARVTGY 354
Query: 348 DPY-VNGTHTILE---------EAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDG 397
DP + ++E EA DA++I T+ + FR +++D+L + M+ +++D
Sbjct: 355 DPEGMENARKLIEGLDCARDPYEAAAEADALVIITEWNEFRALDFDRLKSTMKTPLLVDL 414
Query: 398 RNLVKE---PPKGFIFKGIGRGD 417
RN+ ++ GF + IGR D
Sbjct: 415 RNIYRKDEVAKHGFRYASIGRPD 437
>emb|CAA72087.1| (Y11203) UDP-glucose dehydrogenase [Acetobacter xylinus]
Length = 449
Score = 173 bits (434), Expect = 3e-42
Identities = 134/450 (29%), Positives = 213/450 (46%), Gaps = 41/450 (9%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRIA+IG GY+GL + FA G DV + D + + G I EP + + E V
Sbjct: 1 MRIAMIGGGYVGLVSGTCFAEFGTDVAIVETNPDRLTALREGRIPIYEPGLDRLVEENVE 60
Query: 61 KGKLRATSDY-NDLKGADAFIICVQTP--LSNGVPDLTYLESAIKTIAKVIEKEALVVIE 117
G+L D +KGADA + V TP +G D +Y+ +A++ IA+V + ++V +
Sbjct: 61 AGRLTFGDDIAAAVKGADAVFVAVGTPSRRGDGQADTSYVYAAVEQIARVADGYTVIVTK 120
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV----- 172
STVP GT +A+++ + + DF VA PE + G ++ + R+I G
Sbjct: 121 STVPVGTGREIAQIIRK---TRPDLDFDVASNPEFLREGNAIQDFMRPDRVIIGTDQYKP 177
Query: 173 --SEKASILAEKLYRS--FVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKY 228
+E+A + KLYR ++ I T TAE++K N+F + I NE + L K
Sbjct: 178 EGTERAQNILRKLYRPLYLLETPIVFTGLETAELIKYSANSFLAMKITFINEISDLCEKV 237
Query: 229 GVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLA---NVDEDLGLIRKARKI 283
G NV + R+ K P G GG C PKD L A N + LI +
Sbjct: 238 GANVNDVARSIGLDGRIGKKFLHPSPGFGGSCFPKDTRALTAIGRNAGSPVRLIETTVAV 297
Query: 284 NESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKE 343
NE + + + G D + VLGL +K +TDD+R + ++ + +++K +
Sbjct: 298 NEQRMKDMGERVITFAGG---DVSGLTIGVLGLTFKPETDDMREAASIPVLDMLDKGGAK 354
Query: 344 VRTYDPYVNGTH-----------TILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNK 392
+R +DP T T +A KG D +++ T+ + FR + +KL M+ +
Sbjct: 355 IRAFDPAGMTTARPVLPQSVTYCTDALDAAKGADILVVLTEWNEFRSLAPEKLAAEMKGR 414
Query: 393 IIIDGRNL-----VKEPPKGFIFKGIGRGD 417
I D RN+ +K+ GF + +GR D
Sbjct: 415 KIADLRNIWDPKAIKD--AGFEYISLGRPD 442
>pir||H83393 probable nucleotide sugar dehydrogenase PA2022 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9948026|gb|AAG05410.1|AE004628_8 (AE004628) probable
nucleotide sugar dehydrogenase [Pseudomonas aeruginosa]
Length = 453
Score = 173 bits (434), Expect = 3e-42
Identities = 133/443 (30%), Positives = 210/443 (47%), Gaps = 29/443 (6%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MR+ VIG GY+GL TA FA G+ V + R+ V ++ RG I EP + LR+ +
Sbjct: 1 MRLCVIGAGYVGLVTAACFAEMGNQVRCVERDRERVARLRRGEMPIYEPGLESILRDQLD 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
+L T+ + L A+ I V TP +G DL+++ + + + + + +VV +S
Sbjct: 61 AARLTFTASLAEGLADAEVVFIAVGTPCGEDGSADLSHVLAVAEQLGAQLRQACIVVNKS 120
Query: 119 TVPPGTTERMAKLLE-ELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSR-IIGGVSEKA 176
TVP GT ER+ +++ L ++ VA PE + G + R IIG +A
Sbjct: 121 TVPVGTAERVEEIIRLGLARRRKRFRVAVASNPEFLKEGSAVDDFRRPDRVIIGSAETQA 180
Query: 177 SILAEKLYRSFVKG--RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
+LY F++ R+ L AE K N F I+ NE A L GV++ +
Sbjct: 181 GETLRQLYAPFLRNHERVLLMGRREAEFSKYAANAFLATKISFMNEMAGLCALTGVDIED 240
Query: 235 AIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAA 292
+ R+ H G G GG C PKD L+ + ++ G + + E+
Sbjct: 241 VRRGMGSDKRIGTHFIYAGCGYGGSCFPKDVRALIRSAEQQ-GYDSQILRAVEARNARQK 299
Query: 293 KLLFEALGEANVDPGDA-VVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYV 351
+LLFE LGE V + GLA+K TDD+R +P+L ++ + + VR +DP
Sbjct: 300 ELLFETLGELFQGRWQGRTVALWGLAFKPGTDDLREAPSLVLLEALLRHGVRVRAHDPVA 359
Query: 352 NG----------------THTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIII 395
N H AV+G DA+++ T+ FR+ ++ K+ MR +++
Sbjct: 360 NAGVAARYPEAVACARLTLHDSPYAAVEGADALVLVTEWKQFRQPDFQKIRGSMRTPLLV 419
Query: 396 DGRNL---VKEPPKGFIFKGIGR 415
DGRNL + GFI++GIGR
Sbjct: 420 DGRNLYAPARMAELGFIYQGIGR 442
>gb|AAF23790.1|AF213822_5 (AF213822) UDP-glucose dehydrogenase [Zymomonas mobilis]
Length = 437
Score = 173 bits (433), Expect = 4e-42
Identities = 127/443 (28%), Positives = 216/443 (48%), Gaps = 38/443 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRI +IG GY+GL + F+ GH+VI D ++ + + +G+ I EP + + + V
Sbjct: 1 MRITMIGSGYVGLVSGACFSDIGHNVICVDHDQEKIALLQKGVMPIYEPGLADMVANNVK 60
Query: 61 KGKLRATSDY-NDLKGADAFIICVQTP--LSNGVPDLTYLESAIKTIAKVIEKEALVVIE 117
G+L ++D + +K ADA I V TP +G DL+Y+ +A K IA + +VV +
Sbjct: 61 AGRLSFSNDLASSVKDADAVFIAVGTPSRRGDGHADLSYVFAAAKEIAASVSDNTVVVDK 120
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEKA 176
STVP GT + + +++ E+ K+ +VA PE + G + RI IG + +A
Sbjct: 121 STVPVGTGDEVERIIREIAPDKK---IWVASNPEFLREGAAIGDFKRPDRIVIGTENPEA 177
Query: 177 SILAEKLYRSFV--KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
+ +++YR + I T+ +AE++K N F I NE A L G +V +
Sbjct: 178 REIMQEIYRPLYLNQSPILFTSRRSAELIKYASNAFLATKITFINEMADLCEAVGGDVQD 237
Query: 235 AIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLL---ANVDEDLGLIRKARKINESMPR 289
R+ K G G GG C PKD LL N L ++ N R
Sbjct: 238 VARGIGADNRIGSKFLHAGPGYGGSCFPKDTLALLKTAENFATPLRVVESVVTANNIRKR 297
Query: 290 FAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
A+ + +A+G+ D + +LGL +K +TDD+R++P+L I+ +E + YDP
Sbjct: 298 AMARKVLQAIGK---DMRGQKIGLLGLPFKPNTDDMRDAPSLALIQGLEDAGAIIHAYDP 354
Query: 350 --------------YVNGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIII 395
+ + + + E+A +A++I T+ FR ++ ++ L++ +++
Sbjct: 355 EGMVQARPLLPNVIFEDEPYKVAEKA----EALVIVTEWDAFRALDLKRIAGLLKTPLLL 410
Query: 396 DGRNLVKE---PPKGFIFKGIGR 415
D RN+ E G ++ GIGR
Sbjct: 411 DLRNIYTEEEAKKAGLVYHGIGR 433
>gi|10956342 pXO1-95 [Bacillus anthracis] >gi|7474336|pir||G59102 hypothetical
protein pXO1-95 - Bacillus anthracis virulence plasmid
pXO1 >gi|4894311|gb|AAD32399.1|AAD32399 (AF065404)
pXO1-95 [Bacillus anthracis]
Length = 443
Score = 170 bits (426), Expect = 3e-41
Identities = 123/418 (29%), Positives = 205/418 (48%), Gaps = 26/418 (6%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M I+++G GY+GL T + + GH+V DI + V+K+ G + I EP + E ++ +
Sbjct: 1 MNISIVGTGYVGLVTGVCLSEVGHNVTCIDIDEEKVKKMKLGYSPIFEPCLEELMKNNII 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
KG+L T++Y D GA+ F I V TP +G DL++++ A IA+ I+ + ++V++S
Sbjct: 61 KGRLHFTTNYVDGADGAEIFYIAVGTPQKEDGSADLSFIKQAAINIARTIKNDVIIVVKS 120
Query: 119 TVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASI 178
TVP GT + L+ L L + PE + G + Y RI+ G K S
Sbjct: 121 TVPVGTNIYIKNLI--LKNLNYDVKVDIISNPEFLREGSAVNDTFYGDRIVIGSENKTSA 178
Query: 179 -LAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
+ E++Y+ F IF T +AEM+K NTF I+ N A L G +V + +
Sbjct: 179 NVMEEVYKPF-GTPIFKTDIQSAEMIKYASNTFLATKISFINGIANLCEMVGADVEKVAQ 237
Query: 238 LANTHPRV--KIHRPGIGVGGHCLPKDPYLLL---ANVDEDLGLIRKARKINESMPRFAA 292
R+ + GIG GG C PKD + L+ ++ L+ K+N++
Sbjct: 238 GMGQDKRIGSQFLNAGIGYGGSCFPKDTHALVKVSESLQHKFHLLESVIKLNKNQQTVLI 297
Query: 293 KLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPY-V 351
+ + + G G + L LGL++K +TDD+R +P++ + + ++ +V YDP +
Sbjct: 298 EKIKKRFGSI---VGKKIAL-LGLSFKPNTDDLREAPSIPIARKLVEEGAQVIAYDPVAI 353
Query: 352 NGTHTILEEAVKGVDAIIIATDHSMFREI--EWD--------KLGNLMRNKIIIDGRN 399
+L + V V + + A + + EWD K LM+ +I DGRN
Sbjct: 354 KNAREVLPKEVHYVYSTMEALTEADIALVLTEWDEVVDSLLLKASQLMKEPVIFDGRN 411
>gb|AAG26472.1|AF285774_12 (AF285774) putative UDP-glucose dehydrogenase [Bacteroides
fragilis]
Length = 440
Score = 170 bits (426), Expect = 3e-41
Identities = 132/426 (30%), Positives = 201/426 (46%), Gaps = 33/426 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+IA++G GY+GL T F+ G DV D+ ++ + +GI I EP + + + +
Sbjct: 1 MKIAIVGTGYVGLVTGTCFSEMGVDVTCVDVIESKIDNLKKGIIPIYEPGLEDMVHRNYN 60
Query: 61 KGKLR-ATSDYNDLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
G+L+ TS + L + V TP +G DL Y+ +TI K + LVV +S
Sbjct: 61 AGRLKFTTSLASCLNDVEVVFSAVGTPPDEDGSADLKYVLEVARTIGKTMNHYVLVVTKS 120
Query: 119 TVPPGTTERM-AKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV-SEKA 176
TVP GT +++ A + EL +F VA PE + G + + R++ GV SE+A
Sbjct: 121 TVPVGTAQQVKATIRGELDKRGLNLEFDVASNPEFLKEGDAVDDFMKPDRVVVGVESERA 180
Query: 177 SILAEKLYRSFVKG--RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
+ E+LY+ F+ R+ T +AEM+K N+ I+ N+ A L G NV
Sbjct: 181 KSIMERLYKPFMMNNYRLIFTDIPSAEMIKYAANSMLATRISFMNDIANLCELVGANVNM 240
Query: 235 AIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAA 292
+ R+ K PG G GG C PKD L+ D++ G + K E +
Sbjct: 241 VRKGIGADSRIGSKFLYPGCGYGGSCFPKDVKALIKTADKN-GYSMRVLKAVEEVNNSQK 299
Query: 293 KLLFEAL---GEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
+LF L + N+ G + L GL++K +TDD+R +PAL I I V+ YDP
Sbjct: 300 SILFNKLIRYFDGNLS-GKRIAL-WGLSFKPETDDMREAPALVLIDKILSCGGLVKAYDP 357
Query: 350 ---------------YVNGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKII 394
Y N + +AV DA+++ T+ FR W L M +I
Sbjct: 358 IAVEECKRRIGDSIEYANDMY----DAVLDADALLLVTEWKEFRMPSWGVLKKTMNRALI 413
Query: 395 IDGRNL 400
IDGRN+
Sbjct: 414 IDGRNI 419
>gb|AAG18685.1| (AE004973) UDP-glucose dehydrogenase; Ugd [Halobacterium sp. NRC-1]
Length = 430
Score = 169 bits (424), Expect = 5e-41
Identities = 124/437 (28%), Positives = 212/437 (48%), Gaps = 33/437 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MR++++G GY+G A F GHDV+ DI +D+V+ +N G A I EP + + L
Sbjct: 1 MRVSIVGSGYVGTTVAACFTDMGHDVVNVDIDQDIVDAINAGKAPIHEPGLDD-LLATHG 59
Query: 61 KGKLRATSDYNDLKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEK---EALVVI 116
L AT+DY D+ D + + TP +G D + +E+A +T+ + + + +VV
Sbjct: 60 GDTLAATTDYEDVLETDVTFLALPTPSKEDGSIDTSIIEAAAETLGDTLREKDGDHVVVT 119
Query: 117 ESTV-PPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRII-GGVSE 174
+STV P TTE +A +L + +G + G D +VA PE + G ++ +I+ G SE
Sbjct: 120 KSTVIPRTTTETLAPILADASGKQLGADLHVAMNPEFLREGTAVEDFQNPDKIVFGSDSE 179
Query: 175 KASILAEKLYRSFVK---GRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVN 231
A ++++ ++ + T AEM+K N F ++L N+ + ++GV+
Sbjct: 180 TAIDTLHEIFKPLIEASDATVVETGVEEAEMIKYANNAFLASKVSLINDIGNICKEFGVD 239
Query: 232 VYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDE---DLGLIRKARKINES 286
YE + R+ + R G+G GG C KD ++ E + ++ A +N+
Sbjct: 240 AYEVADAIGLDDRISERFLRSGLGWGGSCFGKDTNAIIHAATETGYEPAMLEAAVAVNDR 299
Query: 287 MPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRT 346
P LL + + D V VLGLA+K TDDVR+S A+ I +++ V
Sbjct: 300 QPERLLSLL-----DDHGDVESERVAVLGLAFKPGTDDVRDSRAIPVINGLQERGANVAA 354
Query: 347 YDPYV---NGTH-------TILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIID 396
YDP TH ++A+ A ++ TD F + D + M ++++D
Sbjct: 355 YDPVAAENMRTHFPDIEYTDAPQDALADASACVVCTDWDEFAVL--DDEFDAMETRVVVD 412
Query: 397 GRNLVKEPPKGFIFKGI 413
GR ++ E G ++G+
Sbjct: 413 GRRII-ERRDGLTYEGL 428
>pir||F82659 UDP-glucose dehydrogenase XF1606 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9106655|gb|AAF84415.1|AE003988_2
(AE003988) UDP-glucose dehydrogenase [Xylella
fastidiosa]
Length = 450
Score = 165 bits (413), Expect = 1e-39
Identities = 131/448 (29%), Positives = 212/448 (47%), Gaps = 35/448 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MR+A+ G GY+GL T A GH+V+ DI + V+ +N G+ I EP + ++ +
Sbjct: 1 MRVAIFGTGYVGLVTGTCLAEVGHEVLCVDINQAKVDGLNCGVIPIYEPGLEPMVKANHA 60
Query: 61 KGKLRATSD--YNDLKGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
G+LR T+D G FI P +G DL Y+ + +TI + I++ +VV +S
Sbjct: 61 TGRLRFTTDSVAAIAHGEITFIAVGTPPDEDGAADLQYVLAVARTIGQCIDRSTIVVNKS 120
Query: 119 TVPPGTTERMAKLLEELTGLKEGED--FYVAHAPERVMPGRIFKELVYNSRI-IGGVSEK 175
TVP GT +++ ++ ++ G D F V PE + G + + RI IG S
Sbjct: 121 TVPVGTADQVRAAIQHEMDVR-GVDFKFEVVSNPEFLKEGDAVADCMRPDRIVIGARSRD 179
Query: 176 ASILAEKLYRSFVKG--RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A + +LY F + RI +AE+ K N I+ NE A +A G ++
Sbjct: 180 AVVRMRRLYAPFNRNHDRIVEMDVRSAELTKYAANAMLATKISFMNEVANIAEYVGADIE 239
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE---DLGLIRKARKINESMP 288
+ + PR+ + PG+G GG C PKD L + D L+ +N +
Sbjct: 240 YVRKGIGSDPRIGWYFIYPGVGYGGSCFPKDVKALARTAQQYGVDPKLLNAVEDVNHAQK 299
Query: 289 RFAAKLL---FEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVR 345
+L+ + GE+ V G V GLA+K +TDD+R +P+ + + K +VR
Sbjct: 300 GHLFELMLRHYGCSGESTVLAGKTFA-VWGLAFKPNTDDMREAPSCRLLVQLWKAGAQVR 358
Query: 346 TYDP-YVNGTHTILEE------------AVKGVDAIIIATDHSMFREIEWDKLGNLMRNK 392
YDP + I E A++ DA+I+ T+ FR ++ + + +++
Sbjct: 359 AYDPEAMQEARRIFGERDDLVFCETAYAALQCADALIVVTEWKQFRSPDFFVIRDALKDA 418
Query: 393 IIIDGRNLVKEPPK----GFIFKGIGRG 416
+I DGRNL +P + G + GIGRG
Sbjct: 419 VIFDGRNLY-DPQEIEEAGLAYYGIGRG 445
>pir||G69988 NDP-sugar dehydrogenase homolog ytcA - Bacillus subtilis
>gi|2293289|gb|AAC00367.1| (AF008220) YtcA [Bacillus
subtilis] >gi|2635570|emb|CAB15064.1| (Z99119) similar
to NDP-sugar dehydrogenase [Bacillus subtilis]
Length = 428
Score = 162 bits (407), Expect = 5e-39
Identities = 121/440 (27%), Positives = 214/440 (48%), Gaps = 38/440 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I V+G GY+GL + AS GHD+I D + ++ +G+ EP + + ++
Sbjct: 1 MKICVVGAGYVGLTLSAALASIGHDMICTDKDVKKIGQLKKGVIPFYEPGLSDA---ILR 57
Query: 61 KGKLRATSDY-NDLKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
G L +S+ + ++ I V TP S+G D L+S I +++ I ++ +S
Sbjct: 58 CGNLSFSSEVKSSMEECPVIFIAVGTPPRSDGSADTKALQSVIGDLSEAIRSYKTIITKS 117
Query: 119 TVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEK--- 175
TVPPGT E +AK L +G+ + F + PE + G ++++ + + GV E+
Sbjct: 118 TVPPGTNENIAKQLIA-SGVSKNL-FNIVSNPEFLREGNALYDMLHPDKTVIGVQEEDHV 175
Query: 176 ASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEA 235
++ + + +Y+ + +T+ AE++K N F I+ NE A + Y ++ +
Sbjct: 176 SAAIVKSIYKH-IDTPFIVTSLAGAELIKYANNFFLAAKISFINEMARICEAYQSDISDI 234
Query: 236 IELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE---DLGLIRKARKINESMPRF 290
PR+ H + GIG GG C PKD L E + L+R + IN++
Sbjct: 235 SRAIGLDPRIGKHFLQAGIGYGGSCFPKDLQALQFAAQEKNTETFLLRAVQHINDTQLGL 294
Query: 291 AAKLL---FEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTY 347
K + FE L VLG+++K +TDD+RNS A+ ++ + + +V Y
Sbjct: 295 YIKKIQSFFETLQGKKA-------AVLGISFKPNTDDIRNSQAVRLMERLAELGCDVHAY 347
Query: 348 DPYVN---------GTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGR 398
DP H+ +A++ D + +AT+ S F +W K ++M+ +++IDGR
Sbjct: 348 DPEAVLPEHLRQHVTQHSQAFDAIEESDFLFLATEWSEFLAFDWKKAADIMKGRLVIDGR 407
Query: 399 NLVKE---PPKGFIFKGIGR 415
N++K+ G I G+GR
Sbjct: 408 NVLKKELIEACGLICTGVGR 427
>pir||B83202 probable nucleotide sugar dehydrogenase PA3559 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9949711|gb|AAG06947.1|AE004776_10 (AE004776)
probable nucleotide sugar dehydrogenase [Pseudomonas
aeruginosa]
Length = 464
Score = 162 bits (406), Expect = 6e-39
Identities = 132/444 (29%), Positives = 208/444 (46%), Gaps = 32/444 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I+V G GY+GL A + A GHDV+ DI R+ VE++ +G+A I EP + LRE +
Sbjct: 1 MKISVFGSGYVGLVQAAVLAEVGHDVLCMDIDRNKVERLAQGLASIYEPGLDALLREGLD 60
Query: 61 KGKLRATSDYNDL--KGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
G+LR +SD G FI P +G DL + IA+ K +VV +S
Sbjct: 61 SGRLRFSSDARLAVEHGRVQFIAVGTPPGEDGAADLGAVFVVADAIAEHRRKPVIVVEKS 120
Query: 119 TVPPGTTERMAKLLEELTGLKEGE-DFYVAHAPERVMPGRIFKELVYNSRIIGGV-SEKA 176
TVP GT +R+ +E E +F + PE + G + RI+ G +E+
Sbjct: 121 TVPVGTGDRLRAHIERRLEADGRELEFEIVSNPEFLKEGSAVADCRRPDRIVVGCDNEEV 180
Query: 177 SILAEKLYRSFVKG--RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
+ +LY F + R+ +AE+ K N I+ N+ A LA G ++
Sbjct: 181 RQVMRELYEPFNRNHDRMLFMGLRSAELTKYAANGMLATKISFINQIAELAEHLGADIEA 240
Query: 235 AIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE---DLGLIRKARKINESMPR 289
+ PR+ H PG G GG C PKD L+ + ++ L++ IN R
Sbjct: 241 VRQGIGADPRIGYHFIYPGCGYGGSCFPKDMRALIHSAEQAHCSSDLLQAVEAINR---R 297
Query: 290 FAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
KL + D + GLA+K +TDD+R++P+ E ++ + + +VR YDP
Sbjct: 298 QKHKLFERIRVFYDGDLRGKTFALWGLAFKPNTDDMRDAPSRELMEALWRHGAQVRAYDP 357
Query: 350 ---------YVNGTHTIL----EEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIID 396
Y + L E + G DA++I T+ F+ +++ L ++ +I D
Sbjct: 358 EAMQETQRLYGHDERLSLMGTPEATLGGADALVICTEWQQFKAPDFELLKERLKAPVIFD 417
Query: 397 GRNLVKEPPK----GFIFKGIGRG 416
GRNL +P + GF + +GRG
Sbjct: 418 GRNLY-DPERMARHGFHYYPMGRG 440
>pir||S74698 UDP-glucose dehydrogenase - Synechocystis sp. (strain PCC 6803)
>gi|1651923|dbj|BAA16849.1| (D90901) UDP-glucose
dehydrogenase [Synechocystis sp.]
Length = 453
Score = 162 bits (405), Expect = 9e-39
Identities = 127/453 (28%), Positives = 218/453 (48%), Gaps = 39/453 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MR+ VIG GY+GL T + A GH VI D + V+ + G + I EP + E + +
Sbjct: 1 MRVCVIGTGYVGLVTGVCLAHIGHQVICVDNNEEKVKLMRAGQSPIYEPGLSELMVANME 60
Query: 61 KGKLRATSDY-NDLKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEKEALVVI-E 117
G+L T+D ++ + I V TP L +G D Y+E+ ++I + ++++ V++ +
Sbjct: 61 SGRLVFTTDLGKGVQESAILFIAVGTPALEDGSSDTRYVEAVARSIGEHLDEQYRVIVNK 120
Query: 118 STVPPGTTERMAKLL-------EELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRII- 169
STVP G+ + + ++ ++ TG +F V PE + G + RI+
Sbjct: 121 STVPIGSGDWVRMIVTEGNEAHQQQTGQAIAVNFDVVSNPEFLREGSAVYDTFNPDRIVL 180
Query: 170 GGVSEKASILAEKLYRSFVKGR-----------IFLTTATTAEMVKLMENTFRDVNIALA 218
GG + +A L +LY ++ R + +T ++AEM+K N F I+
Sbjct: 181 GGNNPQALALMRELYTPLIERRVGENPELPPVPVVMTDLSSAEMIKYAANAFLATKISFI 240
Query: 219 NEFAFLAHKYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGL 276
NE A + + G +V + + R+ K GIG GG C PKD L+ + +D G
Sbjct: 241 NEVANICDRVGADVTQVAQGIGLDSRIGSKFLNAGIGWGGSCFPKDVSALI-HTAKDYGY 299
Query: 277 IRKARKINESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKI 336
+ + ++ E L + V+ +LGL +K DTDD+R++PAL I+
Sbjct: 300 TTSILNAVVEVNQVQRLIVVEKLQQELKILKGKVIGLLGLTFKPDTDDMRDAPALNIIQQ 359
Query: 337 IEKDVKEVRTYDPYV------NGTHTILEEAVKGV-----DAIIIATDHSMFREIEWDKL 385
+ + +V+ YDP V +G + E+ + DA+I+ T+ F ++++ L
Sbjct: 360 LNRLGAKVKAYDPIVSQSGVSHGLSGVKIESTPAMLADQCDALILVTEWQEFLKLDFPVL 419
Query: 386 GNLMRNKIIIDGRNLV---KEPPKGFIFKGIGR 415
+ M +IIDGRN + K GF + G+GR
Sbjct: 420 ASRMHQAVIIDGRNFLDKEKLQGAGFRYLGVGR 452
>emb|CAB82012.1| (AL161755) putative nucleotide-sugar dehydrogenase [Streptomyces
coelicolor A3(2)]
Length = 405
Score = 161 bits (403), Expect = 1e-38
Identities = 121/410 (29%), Positives = 190/410 (45%), Gaps = 34/410 (8%)
Query: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSKG 62
+AVIGLG GLP A ++G +GY + +P +R +++ G
Sbjct: 5 LAVIGLGPYGLPLAQAAVAAGIPTLGYRTGPEA------------DPLTPAEVRRMLATG 52
Query: 63 KLRATSDYN--DLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIEST 119
T +L +IC TP ++G DLT +E+A +T+A + V++ES
Sbjct: 53 FRTPTGPAGPAELGRVRTAVICAPTPPGADGGLDLTQVEAAARTLAAHMRPHTTVILESP 112
Query: 120 VPPGTTERMAK-LLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASI 178
V PGTTE + LLE+ +GL+ G DF++A++P RV PG ++IGG++ +
Sbjct: 113 VRPGTTEDFLRPLLEQGSGLRAGRDFHLAYSPSRVDPGNRDFTPANTPKVIGGLTPACTE 172
Query: 179 LAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIEL 238
A Y + AE V+L+E FR VNIAL NE A L GV++++ +
Sbjct: 173 SAAAFYSRLTDKVVRARGPREAETVQLLETNFRHVNIALVNEMAVLCDDLGVDLWDVLRC 232
Query: 239 ANTHP-RVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAAKLLFE 297
A T P RPG GVGGH + +D L L ++ A+++N MPR+ +
Sbjct: 233 AETKPFGFHAFRPGPGVGGHSVAQD---LTGRAPHSLRMVELAQQVNAQMPRYVVQRAAA 289
Query: 298 ALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGTHTI 357
L E A +L+LG+ YK D D + +PA E + V +DP++ +
Sbjct: 290 LLNEHGKSARGARILLLGVTYKADLADQQATPAEEIATRLMSMGAAVSYHDPHIPSWNVA 349
Query: 358 ---------LEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGR 398
L EA D I+ H + D G ++ ++++D R
Sbjct: 350 DRPVPRADSLYEAAADADLTILLQQHRTY-----DLQGLSVKAQLLLDTR 394
>sp|O07299|ALGD_PSESH GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|2160786|gb|AAB58939.1|
(AF001555) GDP mannose dehydrogenase [Pseudomonas
syringae pv. phaseolicola]
Length = 438
Score = 161 bits (402), Expect = 2e-38
Identities = 124/415 (29%), Positives = 201/415 (47%), Gaps = 44/415 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRI++ GLGY+G A ++ GHDV+G DI ++ +N G + IVEP + E L++ +S
Sbjct: 1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGIS 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEKEA---LVV 115
GKLR T+D+ + ++ D +ICV TP NG +L Y+ES + I V+ +A +V
Sbjct: 61 TGKLRGTTDFAEAIRATDLSMICVGTPSKKNGDLELDYIESVCREIGYVLRDKATRHTIV 120
Query: 116 IESTVPPGTTERMA-KLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
+ STV PGT + +LE+ +G K G DF VA PE + K+ + G +
Sbjct: 121 VRSTVLPGTVANVVIPILEDCSGKKAGVDFGVAVNPEFLRESTAIKDYDLPPMTVIGEFD 180
Query: 175 KAS-ILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
KAS + + LY + I AEM+K N + + ANE +A GV+
Sbjct: 181 KASGDVLQSLYEE-LDAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGR 239
Query: 234 EAIELANTHPRVKIH----RPGIGVGGHCLPKDPYLL---LANVDEDLGLIRKARKINES 286
E +++ + + RPG GG CLPKD L +++D + L+ + N S
Sbjct: 240 EVMDVVCQDKALNLSQYYMRPGFAFGGSCLPKDVRALTYRASSLDVEAPLLNSLMRSNTS 299
Query: 287 MPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEF----------IKI 336
+ A ++ A+ D V +LGL++K TDD+R SP +E + I
Sbjct: 300 QVQNAFDMV------ASYD--TRKVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSI 351
Query: 337 IEKDVKEVRTYD----------PYVNG-THTILEEAVKGVDAIIIATDHSMFREI 380
+ +V+ R + P+V+ ++ ++ + D II+ FR +
Sbjct: 352 FDSNVEYARVHGANKDYIESKIPHVSSLLNSDFDQVINDSDVIILGNRDERFRAL 406
>pir||C70526 probable UDP-glucose dehydrogenase - Mycobacterium tuberculosis
(strain H37RV) >gi|2193943|emb|CAB09606.1| (Z96800) udgA
[Mycobacterium tuberculosis]
Length = 443
Score = 161 bits (402), Expect = 2e-38
Identities = 124/424 (29%), Positives = 202/424 (47%), Gaps = 30/424 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MR +V G GY+G A+ A GH+V+G DI V K+ G EP + + L + ++
Sbjct: 1 MRCSVFGTGYLGATHAVGMAQLGHEVVGVDIDPGKVAKLAGGDIPFYEPGLRKLLTDNLA 60
Query: 61 KGKLRATSDYNDLKG-ADAFIICVQTPLSNGV--PDLTYLESAIKTIAKVIEKEALVVIE 117
G+LR T+DY+ AD + V TP G DL ++ + I + + + +++V +
Sbjct: 61 AGRLRFTTDYDMAADFADVHFLGVGTPQKIGEYGADLRHVHAVIDALVPRLVRASILVGK 120
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV---SE 174
STVP GT + L G D +A PE + G + + RI+ GV S
Sbjct: 121 STVPVGTAAELGHRAGALA--PRGVDVEIAWNPEFLREGFAVHDTLNPDRIVLGVQDDST 178
Query: 175 KASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNV 232
+A + +LY + + +T TAE+VK+ N F I+ N + + G +V
Sbjct: 179 RAEVAVRELYAPLLAAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCEAAGADV 238
Query: 233 YEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLA-----NVDEDLGLIRKARKINE 285
+ + PR+ + G+G GG CLPKD +A D+ L +R+ IN
Sbjct: 239 SQLADALGYDPRIGRQCLNAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINM 298
Query: 286 SMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVR 345
+L A G + + A + VLG A+K ++DDVR+SPAL ++ + V
Sbjct: 299 RRRTKMVELATTACGGSLL---GANIAVLGAAFKPESDDVRDSPALNVAGQLQLNGATVH 355
Query: 346 TYDP-YVNGTHTI---------LEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIII 395
YDP ++ H + + EA + DA+++ T+ F ++E L N +R ++I+
Sbjct: 356 VYDPKALDNAHRLFPTLNYAVSVAEACERADAVLVLTEWREFIDLEPADLANRVRARVIV 415
Query: 396 DGRN 399
DGRN
Sbjct: 416 DGRN 419
>emb|CAB58323.1| (AL121855) UDP-glucose/GDP-mannose family dehydrogenase
[Streptomyces coelicolor A3(2)]
Length = 441
Score = 156 bits (390), Expect = 5e-37
Identities = 113/368 (30%), Positives = 175/368 (46%), Gaps = 24/368 (6%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MR++V GLGY+G +A A GH V+G D+ + V+ VN G A +VE IGE + EVV
Sbjct: 1 MRVSVFGLGYVGCVSAACLAGMGHQVVGVDVNQAKVDLVNDGKAPVVEERIGELIAEVVG 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEA------ 112
G LRAT D + + ++ ++CV TP NG TYLE + I + +
Sbjct: 61 SGALRATGDVREAIMESEISLVCVGTPSEPNGSLCTTYLERVTEEIGTALAERGGGGGRH 120
Query: 113 LVVIESTVPPGT-TERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGG 171
VV ST+ PGT + +LE+ G G DF VA PE + G ++ + + G
Sbjct: 121 TVVFRSTMLPGTCANLLVPILEKYVGGTAGVDFGVAVNPEFLREGTSVRDFFDPPKTVIG 180
Query: 172 VSEKASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVN 231
+ A A + G +F TAE +K +N F + I ANE + H GV+
Sbjct: 181 ELDAAGGDAVLALYDSLPGEVFRVPVATAEAIKYADNAFHGLKIGFANELGAVCHALGVD 240
Query: 232 VYEAIELANTHPRVKIH----RPGIGVGGHCLPKDPYLLL---ANVDEDLGLIRKARKIN 284
++ +++ ++ I RPG GG CLPKD L+ D + ++ N
Sbjct: 241 SHQVMDVFLADRKLNISPAYLRPGFAFGGSCLPKDLRSLVHAAQRADVSVPILSHVLPSN 300
Query: 285 ESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEV 344
+ A +L+ E G+ V + GL++K TDD+R SP +E + + ++
Sbjct: 301 SAHLERAVELV-ERTGKRRVG-------MFGLSFKPGTDDLRESPLVELAERLFGKGYDL 352
Query: 345 RTYDPYVN 352
R +D V+
Sbjct: 353 RIHDANVS 360
>gi|11497917 UDP-glucose dehydrogenase (ugd-1) [Archaeoglobus fulgidus]
>gi|7431386|pir||F69287 UDP-glucose dehydrogenase
(ugd-1) homolog - Archaeoglobus fulgidus
>gi|2650332|gb|AAB90929.1| (AE001084) UDP-glucose
dehydrogenase (ugd-1) [Archaeoglobus fulgidus]
Length = 324
Score = 155 bits (388), Expect = 8e-37
Identities = 105/306 (34%), Positives = 166/306 (53%), Gaps = 14/306 (4%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M++++IG GY+GL T + FA G+ V+ D ++ +N I I EP + E +++ +
Sbjct: 1 MKVSIIGCGYVGLVTGLGFAELGNPVVFVDSNGSKIKSINDLIPPIYEPGLEELIKK--N 58
Query: 61 KGKLRATSDYND-LKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVI-EKE-ALVVI 116
+GK AT+DY + L ++ ICV TP +G DL +E A + K + EKE ++V+
Sbjct: 59 EGKFYATNDYFEALDNSEVSFICVGTPSKEDGSLDLRQVEEASSKLGKALAEKEFHVIVV 118
Query: 117 ESTVPPGTTERMAK-LLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV-SE 174
+STV PGTTE K ++E+ +G K +DF +A PE + G ++ RI+ GV E
Sbjct: 119 KSTVLPGTTENFVKPIIEKESGKKAFDDFGLAMNPEFLREGNAVEDFFNPDRIVIGVKDE 178
Query: 175 KASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
+ + E+LY+ F ++ +T TAEM+K N F I+ ANE + K G++VY+
Sbjct: 179 RTKSVLEELYKPFDCPKL-ITEIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDVYK 237
Query: 235 AIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLL---ANVDEDLGLIRKARKINESMPR 289
E R+ R GIG GG C PKD L+ + EDL +++ ++NE P
Sbjct: 238 VFEGVGLDHRINPSFFRAGIGFGGSCFPKDVRALIRKSEELGEDLQILKAVIEVNEKQPL 297
Query: 290 FAAKLL 295
+LL
Sbjct: 298 KMIELL 303
>gb|AAG19454.1| (AE005038) UDP-glucose dehydrogenase; Udg1 [Halobacterium sp.
NRC-1]
Length = 426
Score = 155 bits (388), Expect = 8e-37
Identities = 118/440 (26%), Positives = 203/440 (45%), Gaps = 43/440 (9%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M ++++G GY+G A FA GH V+ D+ DVV +N G A I EP + ER+ + +
Sbjct: 1 MDVSIVGSGYVGTTIAACFAELGHTVVNVDVDADVVAAINDGDAPIHEPGLAERI-DAHA 59
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVI--EKEALVVIE 117
+LRAT+DY ++ D + + TP +G D + +ES ++ + + + +VV++
Sbjct: 60 GTRLRATTDYEAVRDTDVTFLALPTPAREDGSIDTSIMESGAASLGEALAGADDHMVVVK 119
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAS 177
STV PGTTE + + G +D +A PE + G + + +++ G A+
Sbjct: 120 STVVPGTTEDVVESALVSAGF---DDPLLAMNPEFLRMGSAVDDFRHPDKVVFGARRDAA 176
Query: 178 -----ILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNV 232
+ E L + T AEM+K N F ++L N+ + + GV+
Sbjct: 177 YDQLHAVFEPLLADAGDATVVETGLREAEMIKYANNAFLASKVSLINDLGNICKELGVDA 236
Query: 233 YEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDE---DLGLIRKARKINESM 287
YE + R+ + R G+G GG C PKD + A + + ++ A ++N+
Sbjct: 237 YEVADAIAEDDRISGRFLRSGVGWGGSCFPKDVAAITAAAKDAGYEPAMLEAAVEVNDRQ 296
Query: 288 PRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTY 347
P LL + +VD V VLGL++K TDD+R + A+ I ++ +V Y
Sbjct: 297 PERLLSLL-----DGHVDVAGERVAVLGLSFKPGTDDIRGTRAVPVIDGLQDREADVVAY 351
Query: 348 DP--------------YVNGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKI 393
DP Y + L +AV ++ TD F + D + M ++
Sbjct: 352 DPVAAEKMAEQRPEVTYADSAAGALADAV----GAVVVTDWDEFAAL--DDEFDAMAERV 405
Query: 394 IIDGRNLVKEPPKGFIFKGI 413
++DGR +V +P + G+
Sbjct: 406 VVDGRRVV-DPQADLTYDGL 424
>pir||H83203 GDP-mannose 6-dehydrogenase AlgD PA3540 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949690|gb|AAG06928.1|AE004774_6 (AE004774)
GDP-mannose 6-dehydrogenase AlgD [Pseudomonas
aeruginosa]
Length = 436
Score = 153 bits (384), Expect = 2e-36
Identities = 120/427 (28%), Positives = 205/427 (47%), Gaps = 34/427 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRI++ GLGY+G A ++ GH+VIG D+ ++ +N+G + IVEP + L++
Sbjct: 1 MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQ 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEKEA---LVV 115
G+L T+D+ + +D ICV TP NG DL Y+E+ + I I +++ VV
Sbjct: 61 TGRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVV 120
Query: 116 IESTVPPGTTERMA-KLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVY-NSRIIGGVS 173
+ STV PGT + L+E+ +G K G DF V PE + K+ + +IG +
Sbjct: 121 VRSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPMTVIGELD 180
Query: 174 EKASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
++ L E++YR + I T AEM+K N + + ANE +A GV+
Sbjct: 181 KQTGDLLEEIYRE-LDAPIIRKTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDGR 239
Query: 234 EAIELANTHPRVKIH----RPGIGVGGHCLPKDPYLL---LANVDEDLGLIRKARKINES 286
E +++ ++ + RPG GG CLPKD L + +D + ++ + N +
Sbjct: 240 EVMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEHPMLGSLMRSNSN 299
Query: 287 MPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRT 346
+ A L+ V +LGL++K TDD+R SP +E +++ E+R
Sbjct: 300 QVQKAFDLI--------TSHDTRKVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYELRI 351
Query: 347 YDPYV------NGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNL 400
+D V +E + V +++++ + + LGN +++ +D L
Sbjct: 352 FDRNVEYARVHGANKEYIESKIPHVSSLLVSDLDEVVASSDVLVLGN--GDELFVD---L 406
Query: 401 VKEPPKG 407
V + P G
Sbjct: 407 VNKTPSG 413
>sp|P11759|ALGD_PSEAE GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|65967|pir||DEPSGD GDPmannose
6-dehydrogenase (EC 1.1.1.132) - Pseudomonas aeruginosa
>gi|45268|emb|CAA68425.1| (Y00337) GDPmannose
dehydrogenase (AA 1-436) [Pseudomonas aeruginosa]
Length = 436
Score = 153 bits (382), Expect = 4e-36
Identities = 120/427 (28%), Positives = 204/427 (47%), Gaps = 34/427 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRI++ GLGY+G A ++ GH+VIG D+ ++ +N+G + IVEP + L++
Sbjct: 1 MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQ 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTP-LSNGVPDLTYLESAIKTIAKVIEKEA---LVV 115
G+L T+D+ + +D ICV TP NG DL Y+E+ + I I +++ VV
Sbjct: 61 TGRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVV 120
Query: 116 IESTVPPGTTERMA-KLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVY-NSRIIGGVS 173
+ STV PGT + L+E+ +G K G DF V PE + K+ + +IG +
Sbjct: 121 VRSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPMTVIGELD 180
Query: 174 EKASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
++ L E++YR + I T AEM+K N + + ANE +A GV+
Sbjct: 181 KQTGDLLEEIYRE-LDAPIIRKTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDGR 239
Query: 234 EAIELANTHPRVKIH----RPGIGVGGHCLPKDPYLL---LANVDEDLGLIRKARKINES 286
E +++ ++ + RPG GG CLPKD L + +D + ++ + N +
Sbjct: 240 EVMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEHPMLGSLMRSNSN 299
Query: 287 MPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRT 346
+ A L+ V +LGL++K TDD+R SP +E +++ E R
Sbjct: 300 QVQKAFDLI--------TSHDTRKVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYEFRI 351
Query: 347 YDPYV------NGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNL 400
+D V +E + V +++++ + + LGN +++ +D L
Sbjct: 352 FDRNVEYARVHGANKEYIESKIPHVSSLLVSDLDEVVASSDVLVLGN--GDELFVD---L 406
Query: 401 VKEPPKG 407
V + P G
Sbjct: 407 VNKTPSG 413
>sp|P51585|ALGD_AZOVI GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|1001937|gb|AAB01487.1|
(U11240) GDP-mannose dehydrogenase [Azotobacter
vinelandii]
Length = 436
Score = 152 bits (379), Expect = 1e-35
Identities = 108/350 (30%), Positives = 170/350 (47%), Gaps = 21/350 (6%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MRI++ GLGY+G A + GH+V+G DI ++ +N+G + IVEP +GE L E V
Sbjct: 1 MRISIFGLGYVGAVCAGCLSGRGHEVVGVDISAAKIDMINQGKSPIVEPGLGELLAEGVK 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEA---LVV 115
G+LR T++ + + + ++CV TP NG +L Y+E + + + + VV
Sbjct: 61 TGRLRGTTNVTEAVLATELSMLCVGTPSKLNGDLELDYIEEVCRQMGSALRDKTERHTVV 120
Query: 116 IESTVPPGTTERMA-KLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
+ STV PGT + +LEE +G K G DF VA PE + K+ + + G +
Sbjct: 121 VRSTVLPGTVHNVVIPILEEFSGKKAGVDFGVAVNPEFLRESTAIKDYNFPPMTVIGELD 180
Query: 175 KASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
KAS + + I AEM+K N + + ANE +A GV+ E
Sbjct: 181 KASGRRLASIYAELDAPIVRKGIAVAEMIKYTCNVWHATKVTFANEIGNIAKAAGVDGRE 240
Query: 235 AIELANTHPRVKIH----RPGIGVGGHCLPKDPYLLLANV---DEDLGLIRKARKINESM 287
+E+ ++ + RPG+ GG CLPKD L D + LI + N +
Sbjct: 241 VMEVVCMDNKLNLSQYYMRPGLAFGGSCLPKDVSALSYRAHLWDIEAPLISSLMRSNAAQ 300
Query: 288 PRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII 337
+ A ++ + G V +LGL++K TDD+R SP LE +++
Sbjct: 301 VQKAYDMIDK--------HGSRKVALLGLSFKAGTDDLRESPQLELAEML 342
>gb|AAD43344.1|AF159428_1 (AF159428) putative UDP-glucose dehydrogenase [Burkholderia
pseudomallei]
Length = 466
Score = 147 bits (368), Expect = 2e-34
Identities = 127/460 (27%), Positives = 201/460 (43%), Gaps = 50/460 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I +IG GY+GL T A GHDV D+ ++ +N G I EP + E + +
Sbjct: 1 MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARTRA 60
Query: 61 KGKLRATSDY--NDLKGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
G++ ++D + G FI P +G DL Y+ A + I + + ++V +S
Sbjct: 61 AGRIAFSTDIEASVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGYKVIVDKS 120
Query: 119 TVPPGTTERMAKLLEE------LTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV 172
TVP GT +R+ +++E L G E F V PE + G + + RII GV
Sbjct: 121 TVPVGTAQRVRAVIDEALAARGLAGSAE-HRFSVVSNPEFLKEGAAVDDFMRPDRIIIGV 179
Query: 173 SEKA--SILAE---KLYRSFVKG--RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLA 225
+ A +I E KLY F + R +AE K N I+ NE + LA
Sbjct: 180 DDDAAGAIAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLA 239
Query: 226 HKYGVNVYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDED---LGLIRKA 280
+ G ++ + PR+ H G+G GG C PKD L+ E+ L ++
Sbjct: 240 DRVGADIEALRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTASENGQPLRILEAV 299
Query: 281 RKINESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKD 340
+N + + + G D V GLA+K +TDD+R +P+ I +
Sbjct: 300 EDVNHAQKNVLLDKIEKRYG---ADLAGRTFAVWGLAFKPNTDDMREAPSRRLIASLLAR 356
Query: 341 VKEVRTYDPYV-------------NGTHTI--------LEEAVKGVDAIIIATDHSMFRE 379
VR YDP +G + ++A+ G DA++I T+ F+
Sbjct: 357 GAMVRAYDPVALDEARRVFALDLHDGADALARLAFVDSADDALAGADALVIVTEWKEFKS 416
Query: 380 IEWDKLGNLMRNKIIIDGRNLVKEPPK----GFIFKGIGR 415
++ L ++++ +I DGRNL EP G + IGR
Sbjct: 417 PDFAHLKSVLKAPVIFDGRNLY-EPDAMAELGIDYHAIGR 455
>emb|CAA11569.1| (AJ223832) hypothetical protein [Mycobacterium avium subsp.
silvaticum]
Length = 411
Score = 147 bits (367), Expect = 2e-34
Identities = 104/372 (27%), Positives = 176/372 (46%), Gaps = 27/372 (7%)
Query: 67 TSDYNDLKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKEALVVIESTVPPGTT 125
T ++ AD I V TP+ +G DLTY+ S I I++ ++V +STVP GT
Sbjct: 43 TDRQRGIEHADVIFIAVPTPMGESGAADLTYVFSVADDIGSYIDRYKVIVDKSTVPVGTA 102
Query: 126 ERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEKASILAEKLY 184
+++ ++ K ++F V PE + G+ + + R+ IG S++A + E+LY
Sbjct: 103 DQITAIIRS----KTDQEFDVVSNPEFLKQGKAIADFMQPDRVVIGSDSKRALRIMEELY 158
Query: 185 RSFVKG--RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELANTH 242
F++ + +AEM K N F I+ NE + L K G ++ E
Sbjct: 159 EPFLRTFHPLIAIDVRSAEMAKYAANCFLATKISFINEMSNLCEKAGADISAVREAIGAD 218
Query: 243 PRVKIHR--PGIGVGGHCLPKDPYLLLANVD---EDLGLIRKARKINESMPRFAAKLLFE 297
R+ PGIG GG CLPKD LL D D+ L+R ++N+ +
Sbjct: 219 KRIGYDFLFPGIGYGGSCLPKDVRALLYTADCLGSDMHLLRAVERVNDEQKAALVSKIIT 278
Query: 298 ALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPY-VNGTHT 356
G + + + + GL++K TDDVR +P+L + + + V +DP + T
Sbjct: 279 RFGGSEKNLDGLRIGLWGLSFKPQTDDVRAAPSLVIAEKLVEFGATVCAFDPEAMEQTKK 338
Query: 357 ILEE----------AVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLV---KE 403
+L + AV+G DA+++ T+ F+ W ++ + MR ++ DGRN+ +
Sbjct: 339 VLGDSIEYAGNMYDAVQGADALLLLTEWKQFQRPSWSRVRSAMRGCVVFDGRNIYDPERM 398
Query: 404 PPKGFIFKGIGR 415
+GF + G+GR
Sbjct: 399 KDEGFEYYGMGR 410
>gb|AAD44217.2|AF143772_23 (AF143772) GdhgA [Mycobacterium avium]
Length = 346
Score = 136 bits (338), Expect = 6e-31
Identities = 95/317 (29%), Positives = 152/317 (46%), Gaps = 16/317 (5%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
++I+V+G GY+GL T A SG+DV+ DI + ++ + G I EP + E +
Sbjct: 26 LKISVVGSGYVGLVTGACLADSGNDVVCVDIDQAKIDLLLAGGVPIFEPGLAELIARNRE 85
Query: 61 KGKLRATSD-YNDLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
G + T+D ++ AD I V TP+ +G DLTY+ S I I++ ++V +S
Sbjct: 86 NGLIDFTTDRQRGIEHADVIFIAVPTPMGESGAADLTYVFSVADDIGSYIDRYKVIVDKS 145
Query: 119 TVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSR-IIGGVSEKAS 177
TVP GT +++ ++ K ++F V PE + G+ + + R +IG S++A
Sbjct: 146 TVPVGTADQITAIIRS----KTDQEFDVVSNPEFLKQGKAIADFMQPDRVVIGSDSKRAL 201
Query: 178 ILAEKLYRSFVK--GRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEA 235
+ E+LY F++ + +AEM K N F I+ NE + L K G ++
Sbjct: 202 RIMEELYEPFLRTFHPLIAIDVRSAEMAKYAANCFLATKISFINEMSNLCEKAGADISAV 261
Query: 236 IELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVD---EDLGLIRKARKINESMPRF 290
E R+ PGIG GG CLPKD LL D D+ L+R ++N+
Sbjct: 262 REAIGADKRIGYDFLFPGIGYGGSCLPKDVRALLYTADCLGSDMHLLRAVERVNDEQKAA 321
Query: 291 AAKLLFEALG--EANVD 305
+ G E N+D
Sbjct: 322 LVSKIITRFGGSEKNLD 338
>gb|AAD20371.1| (AF125999) UDP-D-glucose-dehydrogenase gdhgA [Mycobacterium avium]
Length = 346
Score = 134 bits (334), Expect = 2e-30
Identities = 94/317 (29%), Positives = 151/317 (46%), Gaps = 16/317 (5%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
++I+V+G GY+GL T A SG+DV+ DI + ++ + G I EP + E +
Sbjct: 26 LKISVVGSGYVGLVTGACLADSGNDVVCVDIDQAKIDLLLAGSVPIFEPGLAELIARNRE 85
Query: 61 KGKLRATSD-YNDLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
G + T+D ++ AD I V TP+ +G DLTY+ S I I++ ++V +S
Sbjct: 86 NGLIDFTTDRQRGIEHADVIFIAVPTPMGESGAADLTYVFSVADDIGSYIDRYKVIVDKS 145
Query: 119 TVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSR-IIGGVSEKAS 177
TVP GT +++ ++ K ++F V PE + G+ + + R +IG S++A
Sbjct: 146 TVPVGTADQITAIIRS----KTDQEFDVVSNPEFLKQGKAIADFMQPDRVVIGSDSKRAL 201
Query: 178 ILAEKLYRSFVK--GRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEA 235
+ E+LY F++ + +AEM K N F I+ NE + L K G ++
Sbjct: 202 RIMEELYEPFLRTFHPLIAIDVRSAEMAKYAANCFLATKISFINEMSNLCEKAGADISAV 261
Query: 236 IELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVD---EDLGLIRKARKINESMPRF 290
E R+ PGIG G CLPKD LL D D+ L+R ++N+
Sbjct: 262 REAIGADKRIGYDFLFPGIGYGASCLPKDVRALLYTADCLGSDMHLLRAVERVNDEQKAA 321
Query: 291 AAKLLFEALG--EANVD 305
+ G E N+D
Sbjct: 322 LVSKIITRFGGSEKNLD 338
>dbj|BAA99938.1| (AP001309) UDP-glucose dehydrogenase [Arabidopsis thaliana]
Length = 480
Score = 130 bits (324), Expect = 3e-29
Identities = 130/474 (27%), Positives = 199/474 (41%), Gaps = 67/474 (14%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDV--IGYDIRRDVVEKVNRGIAHIVEPEIGERLREV 58
++I IG GY+G PT + A DV DI + N I EP + + +++
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPDVEVAVVDISVPRINAWNSDTLPIYEPGLDDVVKQC 61
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPL------SNGVPDLTYLESAIKTIAKVIEKEA 112
K +T ++ AD + V TP + DLTY ESA + IA V +
Sbjct: 62 RGKNLFFSTDVEKHVREADIVFVSVNTPTKTRGLGAGKAADLTYWESAARMIADVSVSDK 121
Query: 113 LVVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV 172
+VV +STVP T E + K+L T +G F + PE + G K+L R++ G
Sbjct: 122 IVVEKSTVPVKTAEAIEKIL---THNSKGIKFQILSNPEFLAEGTAIKDLFNPDRVLIGG 178
Query: 173 SE-----KASILAEKLYRSFV-KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAH 226
E KA + +Y +V +G+I T +AE+ KL N F I+ N + L
Sbjct: 179 RETPEGFKAVQTLKNVYAHWVPEGQIITTNLWSAELSKLAANAFLAQRISSVNAMSALCE 238
Query: 227 KYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKAR--- 281
G +V + T R+ K +G GG C KD L L + E GL A
Sbjct: 239 ATGADVTQVSYAVGTDSRIGPKFLNSSVGFGGSCFQKD-ILNLVYICECNGLPEVAEYWK 297
Query: 282 ---KINE-SMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII 337
KIN+ RF +++ + + + VLG A+K DT D R +PA++ K +
Sbjct: 298 QVIKINDYQKSRFVNRVVSSMFNSVS----NKKIAVLGFAFKKDTGDTRETPAIDVCKGL 353
Query: 338 EKDVKEVRTYDPYVN------------------------GTHTILE--------EAVKGV 365
+D + YDP V T+ + EA K
Sbjct: 354 LEDKARLSIYDPQVTEDQIQRDLSMNKFDWDHPLHLQPMSPTTVKQVTVTWDAYEATKDA 413
Query: 366 DAIIIATDHSMFREIEWDKL-GNLMRNKIIIDGRNLV---KEPPKGFIFKGIGR 415
I I T+ F+ +++ K+ N+ + + DGRN++ K GFI IG+
Sbjct: 414 HGICIMTEWDEFKNLDFQKIFDNMQKPAFVFDGRNIMNLQKLREIGFIVYSIGK 467
>sp|Q47329|UDG5_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|2126103|pir||S70197 UDP-glucose
dehydrogenase - Escherichia coli
>gi|735963|emb|CAA54708.1| (X77617) UDP-glucose
dehydrogenase [Escherichia coli]
Length = 392
Score = 129 bits (322), Expect = 5e-29
Identities = 108/361 (29%), Positives = 172/361 (46%), Gaps = 28/361 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
++I V G GY+GL I+ A + H+V+ +D + V+ +N ++ I + EI L +
Sbjct: 5 LKITVSGAGYVGLSNGILMAQN-HEVVAFDTHQKKVDLLNDKLSPIEDKEIENYLSTKIL 63
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVP--DLTYLESAIKTIAKVIEKEALVVIES 118
+ T+ Y K A+ II T G D + +E+ I+ + + I A++V++S
Sbjct: 64 NFRA-TTNKYEAYKNANYVIIATPTNYDPGSNYFDTSSVEAVIRDVTE-INPNAIMVVKS 121
Query: 119 TVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRII-GGVSEKAS 177
TVP G T K ++E G+ + +PE + GR + ++ SRII G SE+A
Sbjct: 122 TVPVGFT----KTIKEHLGINN-----IIFSPEFLREGRALYDNLHPSRIIIGECSERAE 172
Query: 178 ILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEA 235
LA +K I T +T AE +KL NT+ + +A NE A +G+N +
Sbjct: 173 RLAVLFQEGAIKQNIPVLFTDSTEAEAIKLFSNTYLAMRVAFFNELDSYAESFGLNTRQI 232
Query: 236 IELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKINESMPRFAA 292
I+ PR+ + P G GG+CLPKD LLAN LI N + F
Sbjct: 233 IDGVCLDPRIGNYYNNPSFGYGGYCLPKDTKQLLANYQSVPNKLISAIVDANRTRKDFIT 292
Query: 293 KLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVN 352
++ + + VV V L K +D+ R+S L IK I+K +V Y+P ++
Sbjct: 293 NVILKHRPQ--------VVGVYRLIMKSGSDNFRDSSILGIIKRIKKKGVKVIIYEPLIS 344
Query: 353 G 353
G
Sbjct: 345 G 345
>emb|CAB46919.2| (AJ242946) putative UDP-glucose dehydrogenase [Streptococcus
uberis]
Length = 401
Score = 128 bits (318), Expect = 1e-28
Identities = 109/368 (29%), Positives = 173/368 (46%), Gaps = 29/368 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+IAV G GY+GL +++ A + V DI V +N+ + I + +I L+E
Sbjct: 1 MKIAVAGSGYVGLSLSVLLAQK-NPVTVVDIIEKKVNLINQKQSPIQDVDIENYLKE--K 57
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTYLESAIKTI---AKVIEKEALVVIE 117
K +LRAT D D DA I+ + TP + V + S ++T+ A + +AL+VI+
Sbjct: 58 KLQLRATLDA-DQAFRDADILIIATPTNYDVEKNFFDTSHVETVIEKALALNSQALLVIK 116
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAS 177
ST+P G ++M + + + + +PE + + K+ +Y SRII + S
Sbjct: 117 STIPLGFIKKMRQ---------KYQTDRIIFSPEFLRESKALKDNLYPSRIIVSFEDDDS 167
Query: 178 ---ILAEKLYRSFVKGR-------IFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHK 227
I A K + +K + + AE VKL NT+ + ++ NE A K
Sbjct: 168 MEVIEAAKTFAQLLKDGSLDKDVPVLFMGSAEAEAVKLFANTYLAMRVSYFNELDTYAEK 227
Query: 228 YGVNVYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKIN 284
G+ V IE R+ IH P G GG+CLPKD LLA D LI+ N
Sbjct: 228 NGLRVDNIIEGVCHDRRIGIHYNNPSFGYGGYCLPKDTKQLLAGYDGIPQSLIKAIVDSN 287
Query: 285 ESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEV 344
+ + A + + L + NVDP DA + + L K ++D+ R S + I I+ +
Sbjct: 288 KIRKEYIASQILQQLSDINVDPKDATIGIYRLIMKSNSDNFRESAIKDIIDHIKSYQINI 347
Query: 345 RTYDPYVN 352
Y+P +N
Sbjct: 348 VLYEPMMN 355
>dbj|BAB11006.1| (AB009054) UDP-glucose dehydrogenase [Arabidopsis thaliana]
Length = 480
Score = 127 bits (317), Expect = 2e-28
Identities = 127/474 (26%), Positives = 201/474 (41%), Gaps = 67/474 (14%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHD--VIGYDIRRDVVEKVNRGIAHIVEPEIGERLREV 58
++I IG GY+G PT + A D V DI + N I EP + + +++
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPDIEVAVVDISVPRINAWNSDQLPIYEPGLDDIVKQC 61
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPL------SNGVPDLTYLESAIKTIAKVIEKEA 112
K +T ++ AD + V TP + DLTY ESA + IA V +
Sbjct: 62 RGKNLFFSTDVEKHVREADIVFVSVNTPTKTTGLGAGKAADLTYWESAARMIADVSVSDK 121
Query: 113 LVVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV 172
+VV +STVP T E + K+L + +G F + PE + G +L R++ G
Sbjct: 122 IVVEKSTVPVKTAEAIEKILMHNS---KGIKFQILSNPEFLAEGTAIADLFNPDRVLIGG 178
Query: 173 SE-----KASILAEKLYRSFV-KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAH 226
E KA +++Y ++V +G+I T +AE+ KL N F I+ N + L
Sbjct: 179 RETPEGFKAVQTLKEVYANWVPEGQIITTNLWSAELSKLAANAFLAQRISSVNAMSALCE 238
Query: 227 KYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKAR--- 281
G +V + T R+ K +G GG C KD L L + + GL A
Sbjct: 239 STGADVTQVSYAVGTDSRIGSKFLNASVGFGGSCFQKD-ILNLVYICQCNGLPEVAEYWK 297
Query: 282 ---KINESMP-RFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII 337
KIN+ RF +++ + + V +LG A+K DT D R +PA++ K +
Sbjct: 298 QVIKINDYQKNRFVNRIVSSMFNTVS----NKKVAILGFAFKKDTGDTRETPAIDVCKGL 353
Query: 338 EKDVKEVRTYDPYVN------------------------GTHTILE--------EAVKGV 365
D ++ YDP V T+ + EA K
Sbjct: 354 LGDKAQISIYDPQVTEEQIQRDLSMKKFDWDHPLHLQPMSPTTVKQVSVTWDAYEATKDA 413
Query: 366 DAIIIATDHSMFREIEWDKL-GNLMRNKIIIDGRNLV---KEPPKGFIFKGIGR 415
A+ + T+ F+ +++ K+ N+ + I DGRN++ K GFI IG+
Sbjct: 414 HAVCVLTEWDEFKSLDYQKIFDNMQKPAFIFDGRNIMNVNKLREIGFIVYSIGK 467
>gb|AAD50493.1|AF172324_11 (AF172324) UDP-Glc-6-dehydrogenase Ugd [Escherichia coli]
Length = 388
Score = 127 bits (316), Expect = 2e-28
Identities = 116/383 (30%), Positives = 179/383 (46%), Gaps = 32/383 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL I+ A + H+V+ DI + V+ +N+ + IV+ EI E L
Sbjct: 1 MKITISGTGYVGLSNGILIAQN-HEVVALDIVQAKVDMLNKKQSPIVDKEIEEYL--ATK 57
Query: 61 KGKLRATSD-YNDLKGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
RAT+D Y+ K AD II T P +N + + +E+ I+ + + I A+++I
Sbjct: 58 DLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYF-NTSSVEAVIRDVTE-INPNAVMII 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEK 175
+ST+P G TE ++E G++ V +PE + G+ + ++ SRI IG S++
Sbjct: 116 KSTIPVGFTES----IKERFGIEN-----VIFSPEFLREGKALYDNLHPSRIVIGEQSDR 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A A L +K I T +T AE +KL NT+ + +A NE A G+N
Sbjct: 167 AERFAALLQEGAIKQDIPILFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSR 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKINESMPRF 290
+ IE PR+ H P G GG+CLPKD LLAN LI N + F
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDF 286
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPY 350
A + + VV V L K +D++R S +K I+ V Y+P
Sbjct: 287 IADSILARKPK--------VVGVYRLIMKSGSDNIRASSIQGIMKRIKAKCVPVIVYEPA 338
Query: 351 VNGTHTILEEAVKGVDAIIIATD 373
+ V+ +DA + D
Sbjct: 339 MKEDDFFRSRVVRDLDAFVQEAD 361
>sp|Q96558|UGDH_SOYBN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|7431381|pir||T08818 probable UDPglucose
6-dehydrogenase (EC 1.1.1.22) - soybean
>gi|1518540|gb|AAB58398.1| (U53418) UDP-glucose
dehydrogenase [Glycine max]
Length = 480
Score = 126 bits (313), Expect = 5e-28
Identities = 130/474 (27%), Positives = 198/474 (41%), Gaps = 67/474 (14%)
Query: 1 MRIAVIGLGYIGLPTAIMFASS--GHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREV 58
++I IG GY+G PT + A +V DI + + N I EP + +++
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPSIEVAVVDISKSRIAAWNSDQLPIYEPGLDGVVKQC 61
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPL------SNGVPDLTYLESAIKTIAKVIEKEA 112
K +T + AD + V TP + DLTY ESA + IA V + +
Sbjct: 62 RGKNLFFSTDVEKHVFEADIVFVSVNTPTKTQGLGAGKAADLTYWESAARMIADVSKSDK 121
Query: 113 LVVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGG 171
+VV +STVP T E + K+ LT +G F + PE + G K+L R+ IGG
Sbjct: 122 IVVEKSTVPVKTAEAIEKI---LTHNSKGIKFQILSNPEFLAEGTAIKDLFNPDRVLIGG 178
Query: 172 ----VSEKASILAEKLYRSFV-KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAH 226
+KA + +Y +V + RI T +AE+ KL N F I+ N + L
Sbjct: 179 RETPEGQKAIQTLKDVYAQWVPEERILTTNLWSAELSKLAANAFLAQRISSVNAMSALCE 238
Query: 227 KYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKAR--- 281
G NV + T R+ K +G GG C KD L L + E GL A
Sbjct: 239 ATGANVQQVSYSVGTDSRIGPKFLNASVGFGGSCFQKD-ILNLVYICECNGLPEVAEYWK 297
Query: 282 ---KINE-SMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII 337
KIN+ RF +++ + + + +LG A+K DT D R +PA++ + +
Sbjct: 298 QVIKINDYQKSRFVNRVVASMFNTVS----NKKIAILGFAFKKDTGDTRETPAIDVCQGL 353
Query: 338 EKDVKEVRTYDPYV--------------NGTHTI------------------LEEAVKGV 365
D + YDP V + H I EA K
Sbjct: 354 LGDKANLSIYDPQVTEDQIQRDLSMNKFDWDHPIHLQPTSPTTVKKVSVVWDAYEATKDA 413
Query: 366 DAIIIATDHSMFREIEWDKL-GNLMRNKIIIDGRNLV---KEPPKGFIFKGIGR 415
+ I T+ F+ +++ K+ N+ + + DGRN+V K GFI IG+
Sbjct: 414 HGLCILTEWDEFKTLDYQKIFDNMQKPAFVFDGRNIVDADKLREIGFIVYSIGK 467
>sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir||E64431 UDPglucose
6-dehydrogenase (EC 1.1.1.22) (intein-containing) -
Methanococcus jannaschii >gi|1591706|gb|AAB99056.1|
(U67548) UDP-glucose dehydrogenase, putative
[Methanococcus jannaschii]
Length = 895
Score = 126 bits (313), Expect = 5e-28
Identities = 95/282 (33%), Positives = 141/282 (49%), Gaps = 27/282 (9%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M I+VIG GY+GL A+ A G DV+G DI V+ +NRG + E + L++ V+
Sbjct: 1 MNISVIGTGYVGLIQAVGLAEFGFDVVGIDIDESKVKALNRGECPLYEEGLEGLLKKHVN 60
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKE--ALVVIE 117
K L T+ Y +K +D +CV TP +G DL +L SA++ I + I+KE ++VI+
Sbjct: 61 K-NLTFTTSYKPIKDSDVIFLCVGTPQDKDGNADLRFLFSAVEKIKETIDKEDYKVIVIK 119
Query: 118 STVPPGTTERMAKLLEELT--------GLKEGEDFYVAHAPERVMPGRIFKELVYNSRII 169
STVP GT R+ +LL++ L+EG Y PERV+ G F+ L
Sbjct: 120 STVPVGTNRRVKELLKDYNVDVVSNPEFLREGIAVYDFFNPERVILG--FENL------- 170
Query: 170 GGVSEKASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHK 227
++K + E++Y+ F I +T TAE++K N F I+ NE A L+ K
Sbjct: 171 --NNKKPIEIMEEVYKYFKDKNIPFVITNWETAELIKYASNAFLATKISFINELAKLSDK 228
Query: 228 YGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLL 267
++ PR+ K GIG GG C D L +
Sbjct: 229 VKADIKTISYAMGLDPRIGNKFLNAGIGYGGSCFHPDEVLFI 270
Score = 71.0 bits (171), Expect = 2e-11
Identities = 57/188 (30%), Positives = 90/188 (47%), Gaps = 35/188 (18%)
Query: 257 HCLPKDPYLLLANVDE---DLGLIRKARKINESMPRFAAKLLFEALGEANVDPGDAVVLV 313
+C PKD L+ + + LI+ +NE K FE + + V
Sbjct: 714 NCFPKDVKALIKQFENNNIEPILIKATDIVNEEQ----IKWFFEKIKNYYGNLNGKTFAV 769
Query: 314 LGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGT--HTI-------------- 357
LGLA+K +TDD+R S A++ I ++ + V+ +D YV +TI
Sbjct: 770 LGLAFKPNTDDLRESRAIKLIDMLLESGAIVKGFD-YVEKARENTINMYKLDKSKGFYGY 828
Query: 358 -------LEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLV---KEPPKG 407
L E VK VD III ++ +E +W+K+GNL++ K++ DGRN++ K G
Sbjct: 829 NLYVLDDLYETVKNVDGIIITVEYDFNKE-DWEKIGNLVKEKVVFDGRNILDVEKIKKLG 887
Query: 408 FIFKGIGR 415
F + G+GR
Sbjct: 888 FKYYGVGR 895
>pir||T44338 hypothetical protein wbfV [imported] - Vibrio cholerae
>gi|3721692|dbj|BAA33642.1| (AB012957) probable
nucleotide sugar dehydrogenase [Vibrio cholerae]
Length = 388
Score = 126 bits (313), Expect = 5e-28
Identities = 120/380 (31%), Positives = 178/380 (46%), Gaps = 40/380 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERL--REV 58
M+IAV G GY+GL AI+ A H VI DI + V +N + IV+ EI L + +
Sbjct: 1 MKIAVAGTGYVGLSNAILLAQH-HQVIAVDIIAEKVAMLNNKQSPIVDQEIEYFLAHKTL 59
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVV 115
+ L S Y D AD II T P +N + T +ES IK + I +A++V
Sbjct: 60 DFQATLDKQSAYRD---ADFVIIATPTDYDPQTNYF-NTTSVESVIKEVM-AINPQAVMV 114
Query: 116 IESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV-SE 174
I+STVP G T R+ L G D + +PE + G+ + ++ SRII G SE
Sbjct: 115 IKSTVPVGYTVRIKNQL--------GCD-NILFSPEFLREGKALHDNLHPSRIIVGERSE 165
Query: 175 KASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNV 232
+A + A L VK I T +T AE VKL NT+ + +A NE A +G++
Sbjct: 166 RAKVFANLLVEGAVKKNIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAEAHGLDA 225
Query: 233 YEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANV----DEDLGLIRKARKINES 286
+ IE PR+ H P G GG+CLPKD LLAN + +G I +A + +
Sbjct: 226 RQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYSSVPNSIIGAIVEANRTRK- 284
Query: 287 MPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRT 346
+ + ++ + VV + L K +D+ R S +K I+ EV
Sbjct: 285 ----------DFVADSIIKRQPKVVGIYRLIMKAGSDNFRASSIQGIMKRIKAKGIEVVV 334
Query: 347 YDPYVNGTHTILEEAVKGVD 366
Y+P +N +K ++
Sbjct: 335 YEPVLNEPEFFHSRVIKDLN 354
>gb|AAD45294.1|AF156256_2 (AF156256) putative dehydrogenase [Vibrio anguillarum]
Length = 237
Score = 125 bits (312), Expect = 7e-28
Identities = 80/233 (34%), Positives = 130/233 (55%), Gaps = 8/233 (3%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
++I +IGLGY+GLP A+ F +G+DI + V +++ GI +E E LR S
Sbjct: 6 VKIGIIGLGYVGLPLAVEFGKK-FSTVGFDINQKRVAELHSGIDLTLECS-EEELR---S 60
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNG-VPDLTYLESAIKTIAKVIEKEALVVIEST 119
L T ++K + +I+ V TP+++ PDL L+ A + +AKV+ +VV EST
Sbjct: 61 APLLSYTHQLEEIKDCNFYIVTVPTPITDEKTPDLNPLKKASEALAKVVSHGDIVVFEST 120
Query: 120 VPPGTTERMA-KLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASI 178
V PG TE + ++E+ +GL DF+ ++PER+ PG L +I G + + +
Sbjct: 121 VYPGATEEVCLPIIEKNSGLVFNRDFFAGYSPERINPGDKVNRLTTIMKITSGSTPEVAD 180
Query: 179 LAEKLYRSFV-KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGV 230
+++Y S V G + AE K++ENT RD+NIA+ NEFA + ++ G+
Sbjct: 181 FVDQVYSSIVTAGTHKAPSIKVAEAAKVIENTQRDLNIAVINEFAKIFNRLGI 233
>gb|AAC67251.2| (AF067175) UDP-glucose dehydrogenase [Pasteurella multocida]
Length = 390
Score = 125 bits (312), Expect = 7e-28
Identities = 108/359 (30%), Positives = 170/359 (47%), Gaps = 28/359 (7%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
+I + G GY+GL A++ A H+VI DI ++ V+ +N + I + EI + L+ S
Sbjct: 3 KITIAGAGYVGLSNAVLLAQH-HNVILLDIDQNKVDLINNKKSPITDKEIEDFLQNK-SL 60
Query: 62 GKLRATSDYNDLKGADAFIICVQTPLSN--GVPDLTYLESAIKTIAKVIEKEALVVIEST 119
+ T LK AD II T + G + + +E+ I+ I +A ++I+ST
Sbjct: 61 TMMATTDKEVALKNADFVIIATPTDYNTETGYFNTSTVEAVIEQTLS-INPQATIIIKST 119
Query: 120 VPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRII-GGVSEKASI 178
+P G TE M + + +PE V G+ + +Y SRII G S +A +
Sbjct: 120 IPVGFTENMREKFNTPN---------LIFSPEFVREGKALYDNLYPSRIIVGSTSYQAKV 170
Query: 179 LAEKLYRSFVKG--RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAI 236
A+ L + K + T T AE VKL NT+ + +A NE A + +N + I
Sbjct: 171 FADMLTQCARKKDVTVLFTHNTEAEAVKLFANTYLAMRVAFFNELDTYASLHHLNTKDII 230
Query: 237 ELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLAN-VDEDLGLIRKARKINESMPRFAAK 293
+T PR+ H P G GG+CLPKD LLAN D LI K NE+ RF
Sbjct: 231 NGISTDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYADVPQNLIEAIVKSNETRKRF--- 287
Query: 294 LLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVN 352
+ + L + G + L K +D+ R S L+ + ++++ E+ Y+P +N
Sbjct: 288 ITHDVLNKKPKTVG-----IYRLIMKSGSDNFRASAILDIMPHLKENGVEIVIYEPTLN 341
>sp|O86422|UDG_PSEAE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3559950|emb|CAA09327.1| (AJ010734)
UDP-glucose 6-dehydrogenase [Pseudomonas aeruginosa]
Length = 452
Score = 125 bits (310), Expect = 1e-27
Identities = 103/339 (30%), Positives = 159/339 (46%), Gaps = 10/339 (2%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MR+ VIG GY+GL TA FA G+ V + R+ V ++ RG I EP + LR+ +
Sbjct: 1 MRLCVIGAGYVGLVTAACFAEMGNQVRCVERDRERVARLRRGEMPIYEPGLESILRDQLD 60
Query: 61 KGKLRATSDYND-LKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
+L T+ + L A+ +I V TP +G DL+++ + + + + + +VV +S
Sbjct: 61 AARLTFTASLAEGLADAEVVLIAVGTPCGEDGSADLSHVLAVAEQLGAQLRQACIVVNKS 120
Query: 119 TVPPGTTERMAKLLE-ELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSR-IIGGVSEKA 176
TVP GT ER+ +++ L ++ VA PE + G + R IIG +A
Sbjct: 121 TVPVGTAERVEEIIRLGLARRRKRFRVAVASNPEFLKEGSAVDDFRRPDRVIIGSAETQA 180
Query: 177 SILAEKLYRSFVKG--RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
+LY F++ R+ L AE K N F I+ NE A L GV++ +
Sbjct: 181 GETLRQLYAPFLRNHERVLLMGRREAEFSKYAANAFLATKISFMNEMAGLCALTGVDIED 240
Query: 235 AIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFAA 292
+ R+ H G G GG C PKD L+ + ++ G + + E+
Sbjct: 241 VRRGMGSDKRIGTHFIYAGCGYGGSCFPKDVRALIRSAEQQ-GYDSQILRAVEARNARQK 299
Query: 293 KLLFEALGEANVDPGDA-VVLVLGLAYKGDTDDVRNSPA 330
+LLFE LGE V + GLA+K TDD+R A
Sbjct: 300 ELLFETLGELFQGRWQGRTVALWGLAFKPGTDDLRERRA 338
>pir||S70888 nucleotide sugar dehydrogenase homolog - Vibrio cholerae
>gi|1230584|gb|AAC46249.1| (U47057) nucleotide sugar
dehydrogenase [Vibrio cholerae O139]
>gi|3724323|dbj|BAA33612.1| (AB012956) probable
nucleotide sugar dehydrogenase [Vibrio cholerae]
>gi|1588978|prf||2209416H nucleotide sugar dehydrogenase
[Vibrio cholerae]
Length = 388
Score = 124 bits (309), Expect = 2e-27
Identities = 118/379 (31%), Positives = 177/379 (46%), Gaps = 38/379 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+IAV G GY+GL A++ A H VI DI + V +N + IV+ EI L
Sbjct: 1 MKIAVAGTGYVGLSNAMLLAQH-HQVIAVDIIAEKVAMLNNKQSPIVDQEIEYFLAHKTL 59
Query: 61 KGKLRATSDYNDL-KGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
+AT D + AD II T P +N + T +ES IK + I +A++VI
Sbjct: 60 D--FQATLDKQSAYRNADFVIIATPTDYDPQTNYF-NTTSVESVIKEVM-AINPQAVMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV-SEK 175
+STVP G T R+ + L G D + +PE + G+ + ++ SRII G SE+
Sbjct: 116 KSTVPVGYTARIKEQL--------GCD-NILFSPEFLREGKALHDNLHPSRIIVGERSER 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A + A L VK I T +T AE VKL NT+ + +A NE A +G++
Sbjct: 167 AEVFANLLVEGAVKKNIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAEAHGLDAR 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANV----DEDLGLIRKARKINESM 287
+ IE PR+ H P G GG+CLPKD LLAN + +G I +A + +
Sbjct: 227 QIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYSSVPNNIIGAIVEANRTRK-- 284
Query: 288 PRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTY 347
+ + ++ + VV + L K +D+ R S +K I+ EV Y
Sbjct: 285 ---------DFVADSIIKRQPKVVGIYRLIMKAGSDNFRASSIQGIMKRIKAKGIEVVVY 335
Query: 348 DPYVNGTHTILEEAVKGVD 366
+P ++ +K +D
Sbjct: 336 EPVLDEPEFFHSRVIKDLD 354
>sp|O33952|UDG8_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|2586097|gb|AAC45829.1| (U78086)
hypothetical uridine-5'-diphosphoglucose dehydrogenase
[Escherichia coli]
Length = 388
Score = 124 bits (308), Expect = 2e-27
Identities = 114/359 (31%), Positives = 171/359 (46%), Gaps = 32/359 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL I+ A + H+V+ DI + V+ +N+ + IV+ EI E L
Sbjct: 1 MKITISGTGYVGLSNGILIAQN-HEVVALDIVQAKVDMLNKKQSPIVDKEIEEYL--ATK 57
Query: 61 KGKLRATSD-YNDLKGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
RAT+D Y+ K AD II T P +N + + +E+ I+ + + I A++VI
Sbjct: 58 DLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYF-NTSSVEAVIRDVTE-INPNAVMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEK 175
+ST+P G T K ++E G+ + +PE + G+ + ++ SRI IG SE+
Sbjct: 116 KSTIPVGFT----KSIKERLGIDN-----LIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A A L +K I T +T AE +KL NT+ + +A NE A G+N
Sbjct: 167 AERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTR 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKINESMPRF 290
+ IE PR+ H P G GG+CLPKD LLAN LI N + F
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDF 286
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
A +A + VV + L K +D+ R S +K I+ EV Y+P
Sbjct: 287 IA--------DAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEP 337
>pir||T51527 UDP-glucose dehydrogenase-like protein - Arabidopsis thaliana
>gi|9755804|emb|CAC01748.1| (AL391143) UDP-glucose
dehydrogenase-like protein [Arabidopsis thaliana]
Length = 480
Score = 123 bits (305), Expect = 5e-27
Identities = 129/474 (27%), Positives = 197/474 (41%), Gaps = 67/474 (14%)
Query: 1 MRIAVIGLGYIGLPTAIMFASS--GHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREV 58
++I IG GY+G PT + A +V DI + N I EP + + +++
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPSVEVAVVDISVPRINAWNSDQLPIYEPGLDDVVKQC 61
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPL------SNGVPDLTYLESAIKTIAKVIEKEA 112
K +T ++ AD + V TP + DLTY ESA + IA V +
Sbjct: 62 RGKNLFFSTDVEKHVREADIVFVSVNTPTKTRGLGAGKAADLTYWESAARMIADVSVSDK 121
Query: 113 LVVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGG 171
+VV +STVP T E + K+ LT +G F + PE + G ++L R+ IGG
Sbjct: 122 IVVEKSTVPVKTAEAIEKI---LTHNSKGIKFQILSNPEFLAEGTAIEDLFMPDRVLIGG 178
Query: 172 VSEKASILAEK----LYRSFV-KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAH 226
A K +Y +V + RI T +AE+ KL N F I+ N + L
Sbjct: 179 RETTEGFAAVKALKDIYAQWVPEERILTTNLWSAELSKLAANAFLAQRISSVNAMSALCE 238
Query: 227 KYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKAR--- 281
G NV E R+ K +G GG C KD L L + E GL A
Sbjct: 239 ATGANVSEVSYAVGKDSRIGPKFLNSSVGFGGSCFQKD-ILNLVYICECNGLPEVAEYWK 297
Query: 282 ---KINE-SMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII 337
KIN+ RF +++ + + + VLG A+K DT D R +PA++ K +
Sbjct: 298 QVIKINDYQKTRFVNRIVSSMFNTVS----NKKIAVLGFAFKKDTGDTRETPAIDVCKGL 353
Query: 338 EKDVKEVRTYDPYVNG-----------------------THTILEE---------AVKGV 365
D + YDP V + T +++ A K
Sbjct: 354 LGDKARLSIYDPQVTEEQIQRDLTMNKFDWDHPLHLQPMSPTTVKQVSVAWDAYTATKDA 413
Query: 366 DAIIIATDHSMFREIEWDKL-GNLMRNKIIIDGRNLV---KEPPKGFIFKGIGR 415
I I T+ F+++++ ++ N+ + + DGRN+V K GFI IG+
Sbjct: 414 HGICILTEWDEFKKLDFQRIFENMQKPAFVFDGRNVVDADKLREIGFIVYSIGK 467
>gb|AAF98561.1|AC013427_4 (AC013427) Strong similarity to UDP-Glucose 6-Dehydrogenase from
Glycine max gb|6136119 and is a member of the
UDP-glucose/GDP-mannose dehydrogenase PF|00984 family.
ESTs gb|AV566422, gb|AV555903 come from this gene.
[Arabidopsis thaliana]
Length = 481
Score = 122 bits (304), Expect = 6e-27
Identities = 125/475 (26%), Positives = 197/475 (41%), Gaps = 68/475 (14%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHD--VIGYDIRRDVVEKVNRGIAHIVEPEIGERLREV 58
++I IG GY+G PT + A + V+ DI + N I EP + + +++
Sbjct: 2 VKICCIGAGYVGGPTMAVMALKCPEIEVVVVDISEPRINAWNSDRLPIYEPGLEDVVKQC 61
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPL------SNGVPDLTYLESAIKTIAKVIEKEA 112
K +T + +D + V TP + DLTY ESA + IA V +
Sbjct: 62 RGKNLFFSTDVEKHVFESDIVFVSVNTPTKTQGLGAGKAADLTYWESAARMIADVSKSSK 121
Query: 113 LVVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGG 171
+VV +STVP T E + K+ LT +G +F + PE + G K+L R+ IGG
Sbjct: 122 IVVEKSTVPVRTAEAIEKI---LTHNSKGIEFQILSNPEFLAEGTAIKDLYNPDRVLIGG 178
Query: 172 ----VSEKASILAEKLYRSFVK-GRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAH 226
+KA +Y +V +I T +AE+ KL N F I+ N + L
Sbjct: 179 RDTAAGQKAIKALRDVYAHWVPVEQIICTNLWSAELSKLAANAFLAQRISSVNAMSALCE 238
Query: 227 KYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKAR--- 281
G +V + T R+ K +G GG C KD L L + E GL A
Sbjct: 239 ATGADVTQVAHAVGTDTRIGPKFLNASVGFGGSCFQKD-ILNLIYICECNGLPEAANYWK 297
Query: 282 ---KINESMP-RFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII 337
K+N+ RFA +++ + + +LG A+K DT D R +PA++ +
Sbjct: 298 QVVKVNDYQKIRFANRVVSSMFNTVS----GKKIAILGFAFKKDTGDTRETPAIDVCNRL 353
Query: 338 EKDVKEVRTYDPYV--------------NGTHTI-------------------LEEAVKG 364
D ++ YDP V + H + EA K
Sbjct: 354 VADKAKLSIYDPQVLEEQIRRDLSMARFDWDHPVPLQQIKAEGISEQVNVVSDAYEATKD 413
Query: 365 VDAIIIATDHSMFREIEWDKL-GNLMRNKIIIDGRNL---VKEPPKGFIFKGIGR 415
+ + T+ F+ +++ K+ N+ + + DGRN+ VK GFI IG+
Sbjct: 414 AHGLCVLTEWDEFKSLDFKKIFDNMQKPAFVFDGRNVVDAVKLREIGFIVYSIGK 468
>dbj|BAB07427.1| (AP001519) nucleotide sugar dehydrogenase [Bacillus halodurans]
Length = 388
Score = 122 bits (304), Expect = 6e-27
Identities = 105/364 (28%), Positives = 172/364 (46%), Gaps = 32/364 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M I + G GY+GL A++ A +DVI YDI ++ V+ +N + IV+ EI E L
Sbjct: 1 MNITIAGTGYVGLSNAVLLAQH-NDVIAYDIVQEKVDMINNRKSPIVDREIEEFL--ATK 57
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTYLES----AIKTIAKVIEKEALVVI 116
+ L AT+D + DA + + TP +N P+ Y ++ A+ + I A++VI
Sbjct: 58 ELNLTATTD-KEKAFKDAQFVVISTP-TNYDPEKNYFDTSSVEAVISDVLSINPNAVMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV-SEK 175
+ST+P G T + + + +PE + G + ++ SRI+ G +++
Sbjct: 116 KSTIPVGYTREVNERFNTKN---------IIFSPEFLREGSALYDNLHPSRIVVGERTQR 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A I A L + +K I T +T AE +KL NT+ + +A NE A G++
Sbjct: 167 AKIFAALLVQGAIKENIDVLFTDSTEAEAIKLFANTYLAMRVAFFNELDSYAELKGLDAK 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANV-DEDLGLIRKARKINESMPRF 290
+ I+ PR+ H P G GG+CLPKD LLAN D +I N++
Sbjct: 227 QIIDGVGLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANFEDVPNNIIGAIVDANDTRKDH 286
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPY 350
A ++ + +P VV + L K +D+ R S L+ + + EV Y+P
Sbjct: 287 VANMILKR------EP--KVVGIYRLTMKTGSDNFRQSAILDVMTRLNNAGAEVVVYEPA 338
Query: 351 VNGT 354
++ T
Sbjct: 339 LDAT 342
>gb|AAF04455.1|AF053973_1 (AF053973) UDP-glucose dehydrogenase [Populus tremula x Populus
tremuloides]
Length = 481
Score = 122 bits (303), Expect = 8e-27
Identities = 127/475 (26%), Positives = 196/475 (40%), Gaps = 68/475 (14%)
Query: 1 MRIAVIGLGYIGLPTAIMFASS--GHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREV 58
++I IG GY+G PT + A +V+ DI + N I EP + + ++E
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPSIEVVVVDIWEPRIAAWNSDQLPIYEPGLYDVVKEC 61
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPL------SNGVPDLTYLESAIKTIAKVIEKEA 112
+ + + AD + V TP + DLTY ESA +TIA V + +
Sbjct: 62 RGRNLFFSKDVEKHVAEADIVFVSVNTPTKTQGLGAGKAADLTYWESAARTIADVSKSDK 121
Query: 113 LVVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGG 171
+VV +STVP T E + K+ LT +G F + PE + G +L R+ IGG
Sbjct: 122 IVVEKSTVPVKTAEAIEKI---LTHNSKGIKFQILSNPEFLAEGTAIGDLFQPDRVLIGG 178
Query: 172 ----VSEKASILAEKLYRSFV-KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAH 226
+KA + +Y +V + RI T +AE+ KL N F I+ N + L
Sbjct: 179 RETPEGQKAIQALKDVYAHWVPEDRILTTNLWSAELSKLAANAFLAQRISSVNAMSALCE 238
Query: 227 KYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKAR--- 281
G +V E R+ K +G GG C KD L L + E GL A
Sbjct: 239 ATGADVAEVSYAVGKDSRIGPKFLNASVGFGGSCFQKD-ILNLVYICECNGLPEVAEYWK 297
Query: 282 ---KINE-SMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKII 337
KIN+ RF +++ + + +LG A+K DT D R +PA++ + +
Sbjct: 298 QVIKINDYQKSRFVNRVVSSMFNTVS----QKKIAILGFAFKKDTGDTRETPAIDVCQGL 353
Query: 338 EKDVKEVRTYDPYVNGTHTILE---------------------------------EAVKG 364
D + YDP V H + EA K
Sbjct: 354 LGDKALLSIYDPQVQKEHIQRDLIMKKFDWDHPLHLQPKSASSAVEQVTVTSDAYEATKE 413
Query: 365 VDAIIIATDHSMFREIEWDKL-GNLMRNKIIIDGRNLV---KEPPKGFIFKGIGR 415
+ I T+ F+ ++++K+ N+ + + DGRN+V K GFI IG+
Sbjct: 414 AHGVCILTEWDEFKTLDYNKIYDNMQKPAFVFDGRNVVNADKLREIGFIVYSIGK 468
>pir||F82417 UDP-glucose 6-dehydrogenase VCA0780 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9658204|gb|AAF96678.1|
(AE004406) UDP-glucose 6-dehydrogenase [Vibrio cholerae]
Length = 388
Score = 122 bits (303), Expect = 8e-27
Identities = 118/362 (32%), Positives = 169/362 (46%), Gaps = 32/362 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+IA+ G GY+GL I+ A ++V+ DI VE++N I+ I +PEI L+
Sbjct: 1 MKIAIAGTGYVGLSNGILLAQH-NEVVALDIVVSRVEQLNDKISPIADPEIESFLQH--Q 57
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVP----DLTYLESAIKTIAKVIEKEALVVI 116
RAT D D DA + + TP D +E+ I + I +A++VI
Sbjct: 58 PLNFRATCDKRDAY-QDAQFVVIATPTDYDPQTNHFDTRTVEAVIDDVL-AINPQAIMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRII-GGVSEK 175
+STVP G T+R+ + L + +PE + GR + +Y SRII G SE+
Sbjct: 116 KSTVPVGYTKRIKQRLCCNN---------LIFSPEFLREGRALYDNLYPSRIIVGEKSER 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A L + K I LT +T AE VKL NT+ + ++ NE A +G++
Sbjct: 167 GQAFATLLAQGAKKMDIPILLTHSTEAEAVKLFSNTYLAMRVSFFNELDTYAETHGLDTK 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANV-DEDLGLIRKARKINESMPRF 290
+ IE PR+ H P G GG+CLPKD LL N D LIR N +
Sbjct: 227 QIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTRQLLRNFEDVPNNLIRAIVDANTTRKDH 286
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPY 350
A F L N +P VV + L K +D+ R S L +K I+ EV Y+P
Sbjct: 287 IA---FSIL---NRNP--KVVGIYRLIMKSGSDNFRASSILGIMKRIKAQGVEVVIYEPV 338
Query: 351 VN 352
+N
Sbjct: 339 LN 340
>gb|AAG35229.1| (AF176369) UDP-glucose-6-dehydrogenase [Escherichia coli]
Length = 388
Score = 122 bits (303), Expect = 8e-27
Identities = 115/359 (32%), Positives = 166/359 (46%), Gaps = 32/359 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL ++ A + H+V+ DI V +N I+ IV+ EI + L+
Sbjct: 1 MKITISGTGYVGLSNGLLIAQN-HEVVALDILPSRVAMLNDRISPIVDKEIQQFLQS--D 57
Query: 61 KGKLRATSDYNDL-KGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
K AT D N+ + AD II T P +N + + +ES IK + + I A++VI
Sbjct: 58 KIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYF-NTSSVESVIKDVVE-INPYAVMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEK 175
+STVP G TE M K + +PE + G+ + ++ SRI IG SE+
Sbjct: 116 KSTVPVGFTEAMHKKYRTEN---------IIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A A L +K I T +T AE +KL NT+ + +A NE A G+N
Sbjct: 167 AERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTR 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKINESMPRF 290
+ IE PR+ H P G GG+CLPKD LLAN LI N + F
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDF 286
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
A +A + VV + L K +D+ R S +K I+ EV Y+P
Sbjct: 287 IA--------DAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEP 337
>gb|AAC45348.1| (U90519) putative UDP-glucose dehydrogenase [Escherichia coli]
Length = 388
Score = 122 bits (302), Expect = 1e-26
Identities = 114/377 (30%), Positives = 177/377 (46%), Gaps = 32/377 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL ++ A + H+V+ DI + V+ +N+ I+ IV+ EI E L E
Sbjct: 1 MKITISGTGYVGLSNGVLIAQN-HEVVALDIVQAKVDMLNQKISPIVDKEIQEYLAE--K 57
Query: 61 KGKLRATSDYNDL-KGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
RAT+D +D + AD II T P +N T +E+ I+ + + I A+++I
Sbjct: 58 PLNFRATTDKHDAYRNADYVIIATPTDYDPKTNYFNTST-VEAVIRDVTE-INPNAVMII 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEK 175
+ST+P G T ++E G+ V +PE + GR + ++ SRI IG S +
Sbjct: 116 KSTIPVGFTRD----IKERLGIDN-----VIFSPEFLREGRALYDNLHPSRIVIGERSAR 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A A+ L +K I T +T AE +KL NT+ + +A NE A G+N
Sbjct: 167 AERFADLLKEGAIKQDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYAESQGLNSK 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKINESMPRF 290
+ IE PR+ H P G GG+CLPKD LLAN + +I N + F
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYESVPNNIIAAIVDANRTRKDF 286
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPY 350
+ ++ + VV V L K +D+ R S +K I+ V Y+P
Sbjct: 287 --------ISDSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIPVIIYEPV 338
Query: 351 VNGTHTILEEAVKGVDA 367
+ V+ +DA
Sbjct: 339 MQEDEFFNSRVVRDLDA 355
>dbj|BAA77737.1| (AB008676) UDP-glucose-6-dehydrogenase [Escherichia coli]
>gi|11464509|gb|AAG35214.1| (AF176356)
UDP-glucose-6-dehydrogenase [Escherichia coli]
Length = 388
Score = 121 bits (301), Expect = 1e-26
Identities = 115/359 (32%), Positives = 166/359 (46%), Gaps = 32/359 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL ++ A + H+V+ DI V +N I+ IV+ EI + L+
Sbjct: 1 MKITISGTGYVGLSNGLLIAQN-HEVVALDILPSRVAMLNDRISPIVDKEIQQFLQS--D 57
Query: 61 KGKLRATSDYNDL-KGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
K AT D N+ + AD II T P +N + + +ES IK + + I A++VI
Sbjct: 58 KIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYF-NTSSVESVIKDVVE-INPYAVMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEK 175
+STVP G TE M K + +PE + G+ + ++ SRI IG SE+
Sbjct: 116 KSTVPVGFTEAMHKKYRTEN---------IIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A A L +K I T +T AE +KL NT+ + +A NE A G+N
Sbjct: 167 AERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSR 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKINESMPRF 290
+ IE PR+ H P G GG+CLPKD LLAN LI N + F
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDF 286
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
A +A + VV + L K +D+ R S +K I+ EV Y+P
Sbjct: 287 IA--------DAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEP 337
>sp|Q19905|UGDH_CAEEL PROBABLE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE)
(UDP-GLCDH) (UDPGDH) >gi|7500161|pir||T21550
hypothetical protein F29F11.1 - Caenorhabditis elegans
>gi|3876536|emb|CAA98269.1| (Z73974) Similarity to
Xanthomonas UDP-glucose dehydrogenase (TR:G747911),
contains similarity to Pfam domain: PF00984
(UDP-glucose/GDP-mannose dehydrogenase family),
Score=750.5, E-value=2.3e-222, N=1 [Caenorhabditis
elegans]
Length = 481
Score = 121 bits (300), Expect = 2e-26
Identities = 115/447 (25%), Positives = 185/447 (40%), Gaps = 50/447 (11%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHD--VIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVV 59
++ +G GY+G PT M A V D+ + + N I EP + E +
Sbjct: 11 KVVCVGAGYVGGPTCAMIAHKCPHITVTVVDMNTAKIAEWNSDKLPIYEPGLDEIVFAAR 70
Query: 60 SKGKLRATSDYNDLKGADAFIICVQTPLS------NGVPDLTYLESAIKTIAKVIEKEAL 113
+ ++ + AD I V TP PDL Y+ES +TIA+ +
Sbjct: 71 GRNLFFSSDIPKAIAEADLIFISVNTPTKMYGRGKGMAPDLKYVESVSRTIAQYAGGPKI 130
Query: 114 VVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGV 172
VV +STVP E + +L E E F V PE + G K+L R+ IGG
Sbjct: 131 VVEKSTVPVKAAESIGCILREAQKNNENLKFQVLSNPEFLAEGTAMKDLANPDRVLIGGE 190
Query: 173 SEKASILA----EKLYRSFV-KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHK 227
S + A ++Y ++V + RI T ++E+ KL+ N F I+ N + +
Sbjct: 191 SSPEGLQAVAELVRIYENWVPRNRIITTNTWSSELSKLVANAFLAQRISSINSISAVCEA 250
Query: 228 YGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKA----- 280
G + E R+ K + +G GG C KD L L + E L L + A
Sbjct: 251 TGAEISEVAHAVGYDTRIGSKFLQASVGFGGSCFQKD-VLSLVYLCESLNLPQVADYWQG 309
Query: 281 --RKINESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIE 338
N RFA K++ E D + + G A+K +T D R S A+ IK +
Sbjct: 310 VININNWQRRRFADKIIAELFNTVT----DKKIAIFGFAFKKNTGDTRESSAIHVIKHLM 365
Query: 339 KDVKEVRTYDPYVNGTHTILE---------------------EAVKGVDAIIIATDHSMF 377
++ ++ YDP V + + + A +G AI++ T+ F
Sbjct: 366 EEHAKLSVYDPKVQKSQMLNDLASVTSAQDVERLITVESDPYAAARGAHAIVVLTEWDEF 425
Query: 378 REIEWDKLGNLMRN-KIIIDGRNLVKE 403
E+ + ++ N M++ I DGR ++ +
Sbjct: 426 VELNYSQIHNDMQHPAAIFDGRLILDQ 452
>sp|Q04873|UDG_SALTY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|485529|pir||S33671 hypothetical protein
(cld 3' region) - Salmonella choleraesuis
>gi|46959|emb|CAA78945.1| (Z17278) putative
UDP-D-glucose dehydrogenase [Salmonella enterica]
Length = 388
Score = 120 bits (298), Expect = 3e-26
Identities = 112/365 (30%), Positives = 168/365 (45%), Gaps = 44/365 (12%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL ++ A HDV+ DI VE +N I+ IV+ EI + L+E
Sbjct: 1 MKITISGTGYVGLSNGLLIAQH-HDVVALDIVPSRVELLNDRISPIVDKEIQQFLKE--D 57
Query: 61 KGKLRATSD-YNDLKGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
+ RAT D ++ + AD II T P +N + + +ES ++ + I A+++I
Sbjct: 58 NIRFRATLDKFDAYQNADYVIIATPTDYDPKTNYF-NTSSVESVMQDVIS-INPAAVMII 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEK 175
+STVP G T M + + +PE + G+ + +Y SRI IG SE+
Sbjct: 116 KSTVPVGFTAAMRQKFATEN---------IIFSPEFLREGKALYDNLYPSRIVIGEQSER 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A A L +K I T +T AE +KL NT+ + +A NE A G+N
Sbjct: 167 AREFAALLQEGAIKQEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAETLGLNTR 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFA 291
+ IE PR+ H P G GG+CLPKD LLAN +S+P
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANY--------------QSVPNNI 272
Query: 292 AKLLFEA-------LGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEV 344
+ EA + +A + VV + L K +D+ R S +K I+ EV
Sbjct: 273 ISAIVEANRTRKDFIADAILARKPKVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEV 332
Query: 345 RTYDP 349
Y+P
Sbjct: 333 IIYEP 337
>sp|P76373|UDG_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|7431378|pir||C64968 hypothetical protein
b2028 - Escherichia coli (strain K-12)
>gi|1736716|dbj|BAA15868.1| (D90841) UDG protein.
[Escherichia coli] >gi|1788340|gb|AAC75089.1| (AE000294)
UDP-glucose 6-dehydrogenase [Escherichia coli K12]
Length = 388
Score = 119 bits (295), Expect = 7e-26
Identities = 114/359 (31%), Positives = 165/359 (45%), Gaps = 32/359 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL ++ A + H+V+ DI V +N I+ IV+ EI + L+
Sbjct: 1 MKITISGTGYVGLSNGLLIAQN-HEVVALDILPSRVAMLNDRISPIVDKEIQQFLQS--D 57
Query: 61 KGKLRATSDYNDL-KGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
K AT D N+ + AD II T P +N + + +ES IK + + I A++VI
Sbjct: 58 KIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYF-NTSSVESVIKDVVE-INPYAVMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEK 175
+STVP G T M K + +PE + G+ + ++ SRI IG SE+
Sbjct: 116 KSTVPVGFTAAMHKKYRTEN---------IIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A A L +K I T +T AE +KL NT+ + +A NE A G+N
Sbjct: 167 AERFAALLQEGAIKQNIPMLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSR 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKINESMPRF 290
+ IE PR+ H P G GG+CLPKD LLAN LI N + F
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDF 286
Query: 291 AAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDP 349
A +A + VV + L K +D+ R S +K I+ EV Y+P
Sbjct: 287 IA--------DAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEP 337
>gb|AAF04239.1|AF093225_1 (AF093225) Vps21 [Vibrio cholerae]
Length = 106
Score = 119 bits (295), Expect = 7e-26
Identities = 55/103 (53%), Positives = 74/103 (71%)
Query: 183 LYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELANTH 242
LY++FVKG +T A TAEM KL EN+FRDVNIA ANE + + +K +NV+E I LAN H
Sbjct: 4 LYKTFVKGECIVTNARTAEMAKLTENSFRDVNIAFANELSLVCNKLKINVWELIRLANRH 63
Query: 243 PRVKIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINE 285
PRV I PG GVGGHC+ DP+ ++ + ++ LIR AR++N+
Sbjct: 64 PRVSILNPGPGVGGHCIAVDPWFIVNSCPDEAQLIRTAREVND 106
>sp|P37791|UDG_SHIFL UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|530776|emb|CAA50782.1| (X71970) frame shift
mutation between 15882 and 15885 [Shigella flexneri]
Length = 372
Score = 117 bits (291), Expect = 2e-25
Identities = 113/362 (31%), Positives = 168/362 (46%), Gaps = 46/362 (12%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL ++ A + H+V+ DI V +N I+ IV+ EI + L+
Sbjct: 1 MKITISGTGYVGLSNGLLIAQN-HEVVALDILPSRVAMLNDRISPIVDKEIQQFLQS--D 57
Query: 61 KGKLRATSDYNDL-KGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
K AT D N+ + AD II T P +N + + +ES IK + + I A++VI
Sbjct: 58 KIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYF-NTSSVESVIKDVVE-INPYAVMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSEK 175
+STVP G T M K + +PE + G+ + ++ SRI IG SE+
Sbjct: 116 KSTVPVGFTAAMHKKYRTEN---------IIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 176 ASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
A A L +K I T +T AE +KL NT+ + +A NE A G+N
Sbjct: 167 AERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTR 226
Query: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINESMPRFA 291
+ IE PR+ H P G GG+CLPKD LLAN +S+P
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANY--------------QSVP--- 269
Query: 292 AKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYV 351
L A+ +AN +V++ K +D+ R S +K I+ EV Y+P +
Sbjct: 270 -NNLISAIVDANRKWWVFIVIM-----KSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVM 323
Query: 352 NG 353
G
Sbjct: 324 KG 325
>sp|Q04872|UDG1_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|485526|pir||S33668 hypothetical protein
(gnd 3' region) - Escherichia coli
>gi|41110|emb|CAA78939.1| (Z17241) putative
UDP-D-glucose dehydrogenase [Escherichia coli]
Length = 388
Score = 117 bits (290), Expect = 3e-25
Identities = 113/363 (31%), Positives = 167/363 (45%), Gaps = 40/363 (11%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL I+ A H+V+ DI VE +N+ + IV+ EI E L
Sbjct: 1 MKITISGTGYVGLSNGILIAQH-HEVVALDIVPTKVEMLNQKKSPIVDKEIEEYL--ATK 57
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTY-----LESAIKTIAKVIEKEALVV 115
+ RAT+D D ++I + TP P Y +ES I+ + I A++V
Sbjct: 58 QLNFRATTDKYDAYRDGTYVI-IATPTDYD-PKTNYFNTSSVESVIRDVVD-INPNAVMV 114
Query: 116 IESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRI-IGGVSE 174
I+ST+P G T LL+E G+ + +PE + GR + ++ SRI IG SE
Sbjct: 115 IKSTIPVGFTN----LLKERLGIDN-----IFFSPEFLREGRALYDNLHPSRIVIGERSE 165
Query: 175 KASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNV 232
+A A L VK I T +T AE +KL NT+ + +A NE A G+N
Sbjct: 166 RAGRFAALLQEGAVKKDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYAESLGLNS 225
Query: 233 YEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANV----DEDLGLIRKARKINES 286
+ IE PR+ H P G GG+CLPKD LLAN + +G I A + +
Sbjct: 226 RQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYASVPNNIIGAIVDANRTRK- 284
Query: 287 MPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRT 346
+ + ++ + VV V L K +D+ R S +K I+ V
Sbjct: 285 ----------DFIADSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGVPVII 334
Query: 347 YDP 349
Y+P
Sbjct: 335 YEP 337
>sp|O02373|UGDH_DROME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) (SUGARLESS PROTEIN) >gi|2149991|gb|AAB58714.1|
(AF000570) UDP-glucose dehydrogenase [Drosophila
melanogaster] >gi|2257994|gb|AAB63208.1| (AF007870)
UDP-glucose dehydrogenase [Drosophila melanogaster]
>gi|2266945|gb|AAB63462.1| (AF009013)
UDP-glucose-6-dehydrogenase [Drosophila melanogaster]
>gi|7295310|gb|AAF50631.1| (AE003560) sgl gene product
[Drosophila melanogaster]
Length = 476
Score = 115 bits (286), Expect = 8e-25
Identities = 112/447 (25%), Positives = 194/447 (43%), Gaps = 51/447 (11%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIG--YDIRRDVVEKVNRGIAHIVEPEIGERLREV 58
M++ IG GY+G PT + A D++ D + + + N I EP + E +++
Sbjct: 1 MKVCCIGAGYVGGPTCAVMALKCPDIVITLVDKSSERIAQWNSDKLPIYEPGLDEVVKKC 60
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPLS---NG---VPDLTYLESAIKTIAKVIEKEA 112
+ +T +K AD I V TP NG DL Y+ESA + IA++ +
Sbjct: 61 RNVNLFFSTDIETAIKEADLIFISVNTPTKTCGNGKGRAADLKYVESAARMIAEIAQSNK 120
Query: 113 LVVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV 172
+VV +STVP E + +L K G + + PE + G +L+ R++ G
Sbjct: 121 IVVEKSTVPVRAAESIMHILR--ANQKPGIHYDILSNPEFLAEGTAINDLLNADRVLIGG 178
Query: 173 SE--KASILAEKL---YRSFVKGRIFLTTAT-TAEMVKLMENTFRDVNIALANEFAFLAH 226
E + EKL Y ++ + LTT T ++E+ KL N F I+ N + +
Sbjct: 179 EETPEGHQAVEKLSWIYEHWIPKQNILTTNTWSSELSKLAANAFLAQRISSINSLSAVCE 238
Query: 227 KYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLL-----ANVDEDLGLIRK 279
G +V E R+ K + +G GG C KD L+ N+ E ++
Sbjct: 239 ATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYICENLNLPEVAAYWQQ 298
Query: 280 ARKINESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEK 339
+NE R ++ + E+L D + +LG A+K +T D R + A+ + + +
Sbjct: 299 VIDMNEYQKRRFSQKIIESLFNT---VSDKRIAILGFAFKKNTGDTRETAAITVCQTLLE 355
Query: 340 DVKEVRTYDPYVNG-------THTILEE-----------------AVKGVDAIIIATDHS 375
+ + YDP V TH + E AV+ A++I T+
Sbjct: 356 EGAALDIYDPKVEPEQIIDDLTHPSVTESPEKVKKAVQIHSDPYSAVRATHALVICTEWD 415
Query: 376 MFREIEWDKL-GNLMRNKIIIDGRNLV 401
F ++++ ++ ++M+ I DGR ++
Sbjct: 416 EFVDLDFKRIYQSMMKPAYIFDGRKIL 442
>gb|AAC97125.1| (AF001310) UDP-glucose dehydrogenase [Drosophila melanogaster]
Length = 476
Score = 115 bits (285), Expect = 1e-24
Identities = 112/447 (25%), Positives = 193/447 (43%), Gaps = 51/447 (11%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIG--YDIRRDVVEKVNRGIAHIVEPEIGERLREV 58
M++ IG GY+G PT + A D++ D + + + N I EP + E ++
Sbjct: 1 MKVCCIGAGYVGGPTCAVMALKCPDIVITLVDKSSERIAQWNSDKLPIYEPGLDEVVKRC 60
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPLS---NG---VPDLTYLESAIKTIAKVIEKEA 112
+ +T +K AD I V TP NG DL Y+ESA + IA++ +
Sbjct: 61 RNVNLFFSTDIETAIKEADLIFISVNTPTKTCGNGKGRAADLKYVESAARMIAEIAQSNK 120
Query: 113 LVVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV 172
+VV +STVP E + +L K G + + PE + G +L+ R++ G
Sbjct: 121 IVVEKSTVPVRAAESIMHILR--ANQKPGIHYDILSNPEFLAEGTAINDLLNADRVLIGG 178
Query: 173 SE--KASILAEKL---YRSFVKGRIFLTTAT-TAEMVKLMENTFRDVNIALANEFAFLAH 226
E + EKL Y ++ + LTT T ++E+ KL N F I+ N + +
Sbjct: 179 EETPEGHQAVEKLSWIYEHWIPKQNILTTNTWSSELSKLAANAFLAQRISSINSLSAVCE 238
Query: 227 KYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLL-----ANVDEDLGLIRK 279
G +V E R+ K + +G GG C KD L+ N+ E ++
Sbjct: 239 ATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYICENLNLPEVAAYWQQ 298
Query: 280 ARKINESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEK 339
+NE R ++ + E+L D + +LG A+K +T D R + A+ + + +
Sbjct: 299 VIDMNEYQKRRFSQKIIESLFNT---VSDKRIAILGFAFKKNTGDTRETAAITVCQTLLE 355
Query: 340 DVKEVRTYDPYVNG-------THTILEE-----------------AVKGVDAIIIATDHS 375
+ + YDP V TH + E AV+ A++I T+
Sbjct: 356 EGAALDIYDPKVEPEQIIDDLTHPSVTESPEKVKKAVQIHSDPYSAVRATHALVICTEWD 415
Query: 376 MFREIEWDKL-GNLMRNKIIIDGRNLV 401
F ++++ ++ ++M+ I DGR ++
Sbjct: 416 EFVDLDFKRIYQSMMKPAYIFDGRKIL 442
>sp|P12378|UGDH_BOVIN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3747091|gb|AAC64183.1| (AF095792)
UDP-glucose dehydrogenase [Bos taurus]
Length = 494
Score = 113 bits (280), Expect = 4e-24
Identities = 112/447 (25%), Positives = 183/447 (40%), Gaps = 54/447 (12%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHD--VIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVV 59
+I IG GY+G PT + A + V DI + N I EP + E +
Sbjct: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDINESRINAWNSPTLPIYEPGLKEVVESCR 65
Query: 60 SKGKLRATSDYNDLKGADAFIICVQTPLSN------GVPDLTYLESAIKTIAKVIEKEAL 113
K +T+ + +K AD I V TP DL Y+E+ + I + +
Sbjct: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSHGYKI 125
Query: 114 VVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVS 173
V +STVP E + ++ + T K + V PE + G K+L R++ G
Sbjct: 126 VTEKSTVPVRAAESIRRIFDANT--KPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183
Query: 174 E-----KASILAEKLYRSFVKGRIFLTTAT-TAEMVKLMENTFRDVNIALANEFAFLAHK 227
E +A +Y +V LTT T ++E+ KL N F I+ N + L
Sbjct: 184 ETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLTANAFLAQRISSINSISALCEA 243
Query: 228 YGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINE 285
G +V E R+ K + +G GG C KD L L + E L L AR +
Sbjct: 244 TGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKD-VLNLVYLCEALNLPEVARYWQQ 302
Query: 286 SMP-------RFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIE 338
+ RFA++++ D + +LG A+K DT D R S ++ K +
Sbjct: 303 VIDMNDYQRRRFASRIIDSLFNTVT----DKKIAILGFAFKKDTGDTRESSSIYISKYLM 358
Query: 339 KDVKEVRTYDPYVNGTHTILE-----------------------EAVKGVDAIIIATDHS 375
+ + YDP V +++ EA G A++I T+
Sbjct: 359 DEGAHLHIYDPKVPREQIVVDLSHPGVSKDDQVARLVTISKDPYEACDGAHAVVICTEWD 418
Query: 376 MFREIEWDKL-GNLMRNKIIIDGRNLV 401
MF+E++++++ +++ I DGR ++
Sbjct: 419 MFKELDYERIHKKMLKPAFIFDGRRVL 445
>pir||JC2525 UDP-glucose dehydrogenase (EC 1.1.99.-) - Xanthomonas campestris
pv. campestris >gi|747911|emb|CAA56166.1| (X79772)
UDP-glucose dehydrogenase [Xanthomonas campestris]
Length = 445
Score = 113 bits (279), Expect = 5e-24
Identities = 94/344 (27%), Positives = 152/344 (43%), Gaps = 27/344 (7%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
MR+A+ G GY+GL T A GH VI DI + V+ +NRG+ I EP + ++ +
Sbjct: 1 MRVAIFGTGYVGLVTGTCLAEVGHHVICVDIDQAKVDGLNRGVIPIYEPGLEPMVKGNHA 60
Query: 61 KGKLRATSDYND--LKGADAFIICVQTPLSNGVPDLTYLESAIKTIAKVIEKEALVVIES 118
G+LR T+D + G FI P +G DL Y+ + +T+ + I+ +++V +S
Sbjct: 61 SGRLRFTTDAAEAIAHGEITFIAVGTPPDEDGSADLQYVLAVARTVGRHIDGPSVIVNKS 120
Query: 119 TVPPGTTERM-AKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAS 177
TVP T +++ A + EEL +F V PE + G + + RI+ G + A+
Sbjct: 121 TVPVRTADKVRAAIQEELDARGVDHEFDVVSNPEFLKEGDAVADCMRPDRIVIGAKKPAA 180
Query: 178 IL-AEKLYRSFVKG--RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYE 234
I +LY F + RI +AE+ K N I+ NE A +A + G +V
Sbjct: 181 IARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEH 240
Query: 235 AIELANTHPRVKIHRPGIGVGGHCLPKDPYLLLAN--------VDEDLG----LIRKARK 282
+ PR +G H + P A+ + G L+
Sbjct: 241 VRNGIGSDPR---------IGWHFIYPVPATARASRRCAGARKTAHEYGMQPTLLNAVES 291
Query: 283 INESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVR 326
+N + +L+ + N V GLA+K +TDD+R
Sbjct: 292 VNNAQKGHLFELVQRHYADGNGSIAGKTFAVWGLAFKPNTDDMR 335
>gi|4507813 UDP-glucose dehydrogenase [Homo sapiens]
>gi|11435916|ref|XP_003427.1| UDP-glucose dehydrogenase
[Homo sapiens] >gi|6175086|sp|O60701|UGDH_HUMAN
UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE)
(UDP-GLCDH) (UDPGDH) >gi|3127127|gb|AAC36095.1|
(AF061016) UDP-glucose dehydrogenase [Homo sapiens]
>gi|3452405|emb|CAA07609.1| (AJ007702) UDPglucose
dehydrogenase [Homo sapiens] >gi|7025909|emb|CAB75891.1|
(AJ272274) UDP-glucose dehydrogenase [Homo sapiens]
Length = 494
Score = 113 bits (279), Expect = 5e-24
Identities = 111/447 (24%), Positives = 183/447 (40%), Gaps = 54/447 (12%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHD--VIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVV 59
+I IG GY+G PT + A + V D+ + N I EP + E +
Sbjct: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCR 65
Query: 60 SKGKLRATSDYNDLKGADAFIICVQTPLSN------GVPDLTYLESAIKTIAKVIEKEAL 113
K +T+ + +K AD I V TP DL Y+E+ + I + +
Sbjct: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125
Query: 114 VVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVS 173
V +STVP E + ++ + T K + V PE + G K+L R++ G
Sbjct: 126 VTEKSTVPVRAAESIRRIFDANT--KPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183
Query: 174 E-----KASILAEKLYRSFVKGRIFLTTAT-TAEMVKLMENTFRDVNIALANEFAFLAHK 227
E +A +Y +V LTT T ++E+ KL N F I+ N + L
Sbjct: 184 ETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEA 243
Query: 228 YGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINE 285
G +V E R+ K + +G GG C KD L L + E L L AR +
Sbjct: 244 TGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKD-VLNLVYLCEALNLPEVARYWQQ 302
Query: 286 SMP-------RFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIE 338
+ RFA++++ D + +LG A+K DT D R S ++ K +
Sbjct: 303 VIDMNDYQRRRFASRIIDSLFNTVT----DKKIAILGFAFKKDTGDTRESSSIYISKYLM 358
Query: 339 KDVKEVRTYDPYVNGTHTILE-----------------------EAVKGVDAIIIATDHS 375
+ + YDP V +++ EA G A++I T+
Sbjct: 359 DEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWD 418
Query: 376 MFREIEWDKL-GNLMRNKIIIDGRNLV 401
MF+E++++++ +++ I DGR ++
Sbjct: 419 MFKELDYERIHKKMLKPAFIFDGRRVL 445
>pir||JE0353 uridine diphosphoglucose dehydrogenase (EC 1.-.-.-) - human
Length = 494
Score = 113 bits (279), Expect = 5e-24
Identities = 110/446 (24%), Positives = 178/446 (39%), Gaps = 52/446 (11%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHD--VIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVV 59
+I IG GY+G PT + A + V D+ + N I EP + E +
Sbjct: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTRRDVNESRINAWNSPTLPIYEPGLKEVVESCR 65
Query: 60 SKGKLRATSDYNDLKGADAFIICVQTPLSN------GVPDLTYLESAIKTIAKVIEKEAL 113
K +T+ + +K AD I V TP DL Y+E+ + I + +
Sbjct: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125
Query: 114 VVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVS 173
V +STVP E + ++ + T K + V PE + G K+L R++ G
Sbjct: 126 VTEKSTVPVRAAESIRRIFDANT--KPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183
Query: 174 EK------ASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHK 227
E L + RI T ++E+ KL N F I+ N + L
Sbjct: 184 ETPEGQRAVQALCAVYEHEVPRERILTTNTWSSELSKLAANAFLAQRISSINSISALCEA 243
Query: 228 YGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKAR---- 281
G +V E R+ K + +G GG C KD L L + E L L AR
Sbjct: 244 TGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKD-VLNLVYLCEALNLPEVARYWQQ 302
Query: 282 --KINESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEK 339
+N+ R A + +AL D + +LG A+K DT D R S ++ K +
Sbjct: 303 VIDMNDYQRRRFASRIIDALFNTVTDKK---IAILGFAFKKDTGDTRESSSIYISKYLMD 359
Query: 340 DVKEVRTYDPYVNGTHTILE-----------------------EAVKGVDAIIIATDHSM 376
+ + YDP V +++ EA G A++I T+ M
Sbjct: 360 EGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDM 419
Query: 377 FREIEWDKL-GNLMRNKIIIDGRNLV 401
F+E++++++ +++ I DGR ++
Sbjct: 420 FKELDYERIHKKMLKPAFIFDGRRVL 445
>gi|6678499 UDP-glucose dehydrogenase [Mus musculus]
>gi|6136117|sp|O70475|UGDH_MOUSE UDP-GLUCOSE
6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3127129|gb|AAC36096.1| (AF061017)
UDP-glucose dehydrogenase [Mus musculus]
Length = 493
Score = 111 bits (276), Expect = 1e-23
Identities = 111/447 (24%), Positives = 183/447 (40%), Gaps = 54/447 (12%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHD--VIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVV 59
+I IG GY+G PT + A + V D+ + N I EP + E +
Sbjct: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCR 65
Query: 60 SKGKLRATSDYNDLKGADAFIICVQTPLSN------GVPDLTYLESAIKTIAKVIEKEAL 113
K +T+ + ++ AD I V TP DL Y+E+ + I + +
Sbjct: 66 GKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125
Query: 114 VVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVS 173
V +STVP E + ++ + T K + V PE + G K+L R++ G
Sbjct: 126 VTEKSTVPVRAAESIRRIFDANT--KPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183
Query: 174 E-----KASILAEKLYRSFVKGRIFLTTAT-TAEMVKLMENTFRDVNIALANEFAFLAHK 227
E KA +Y +V LTT T ++E+ KL N F I+ N + L
Sbjct: 184 ETPEGQKAVRALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCEA 243
Query: 228 YGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINE 285
G +V E R+ K + +G GG C KD L L + E L L AR +
Sbjct: 244 TGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKD-VLNLVYLCEALNLPEVARYWQQ 302
Query: 286 SMP-------RFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIE 338
+ RFA++++ D + +LG A+K DT D R S ++ K +
Sbjct: 303 VIDMNDYQRRRFASRIIDSLFNTVT----DKKIAILGFAFKKDTGDTRESSSIYISKYLM 358
Query: 339 KDVKEVRTYDPYVNGTHTILE-----------------------EAVKGVDAIIIATDHS 375
+ + YDP V +++ EA G A++I T+
Sbjct: 359 DEGAHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWD 418
Query: 376 MFREIEWDKL-GNLMRNKIIIDGRNLV 401
MF+E++++++ +++ I DGR ++
Sbjct: 419 MFKELDYERIHKKMLKPAFIFDGRRVL 445
>pir||A54926 UDPglucose 6-dehydrogenase (EC 1.1.1.22) - bovine
>gi|806944|gb|AAB32227.1| UDP-glucose dehydrogenase,
UDPGDH=52 kda subunit {EC 1.1.1.22} [cattle, liver,
Peptide, 468 aa]
Length = 468
Score = 111 bits (274), Expect = 2e-23
Identities = 112/447 (25%), Positives = 185/447 (41%), Gaps = 55/447 (12%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHD--VIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVV 59
+I IG GY+G PT + A + V DI + N I EP + E +
Sbjct: 6 KICCIGAGYVGGPTCSVIAHMCPEIRVTVVDINESRINAWNSPTLPIYEPGLKEVVESCR 65
Query: 60 SKGKLRATSDYNDLKGADAFIICVQTPLSN------GVPDLTYLESAIKTIAKVIEKEAL 113
K +T+ + +K AD I V TP DL Y+E+ + I + +
Sbjct: 66 GKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSHGYKI 125
Query: 114 VVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVS 173
V +STVP E + ++ + T K + V++ PE + G K+L R++ G
Sbjct: 126 VTEKSTVPVRAAESIRRIFDANT--KPNLNLQVSN-PEFLAEGTAIKDLKNPDRVLIGGD 182
Query: 174 E-----KASILAEKLYRSFVKGRIFLTTAT-TAEMVKLMENTFRDVNIALANEFAFLAHK 227
E +A +Y +V LTT T ++E+ KL N F I+ N + L
Sbjct: 183 ETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLTANAFLAQRISSINSISALCEA 242
Query: 228 YGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINE 285
G +V E R+ K + +G GG C KD L L + E L L AR +
Sbjct: 243 TGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKD-VLNLVYLCEALNLPEVARYWQQ 301
Query: 286 SMP-------RFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIE 338
+ RFA++++ D + +LG A+K DT D R S ++ K +
Sbjct: 302 VIDMNDYQRRRFASRIIDSLFNTVT----DKKIAILGFAFKKDTGDTRESSSIYISKYLM 357
Query: 339 KDVKEVRTYDPYVNGTHTILE-----------------------EAVKGVDAIIIATDHS 375
+ + YDP V +++ EA G A++I T+
Sbjct: 358 DEGAHLHIYDPKVPREQIVVDLSHPGVSKDDQVARLVTISKDPYEACDGAHAVVICTEWD 417
Query: 376 MFREIEWDKL-GNLMRNKIIIDGRNLV 401
MF+E++++++ +++ I DGR ++
Sbjct: 418 MFKELDYERIHKKMLKPAFIFDGRRVL 444
>sp|O70199|UGDH_RAT UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3133257|dbj|BAA28215.1| (AB013732)
UDP-glucose dehydrogeanse [Rattus norvegicus]
Length = 493
Score = 110 bits (273), Expect = 3e-23
Identities = 110/447 (24%), Positives = 183/447 (40%), Gaps = 54/447 (12%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHD--VIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVV 59
+I IG GY+G PT + A + V D+ + N I EP + E +
Sbjct: 6 KICCIGAGYVGGPTCSVIARMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCR 65
Query: 60 SKGKLRATSDYNDLKGADAFIICVQTPLSN------GVPDLTYLESAIKTIAKVIEKEAL 113
K +T+ + ++ AD I V TP DL Y+E+ + I + +
Sbjct: 66 GKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKI 125
Query: 114 VVIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVS 173
V +STVP E + ++ + T K + V PE + G K+L R++ G
Sbjct: 126 VTEKSTVPVRAAESIRRIFDANT--KPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGD 183
Query: 174 E-----KASILAEKLYRSFVKGRIFLTTAT-TAEMVKLMENTFRDVNIALANEFAFLAHK 227
E +A +Y +V LTT T ++E+ KL N F I+ N + L
Sbjct: 184 ETPEGQRAVQALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCES 243
Query: 228 YGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVDEDLGLIRKARKINE 285
G +V E R+ K + +G GG C KD L L + E L L AR +
Sbjct: 244 TGADVEEVATAIGMDQRIGNKFLKASVGFGGGCFQKD-VLNLVYLCEALNLPEVARYWQQ 302
Query: 286 SMP-------RFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIE 338
+ RFA++++ D + +LG A+K DT D R S ++ K +
Sbjct: 303 VIDMNDYQRRRFASRIIDSLFNTVT----DKKIAILGFAFKKDTGDTRESSSIYISKYLM 358
Query: 339 KDVKEVRTYDPYVNGTHTILE-----------------------EAVKGVDAIIIATDHS 375
+ + YDP V +++ EA G A++I T+
Sbjct: 359 DEGAHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWD 418
Query: 376 MFREIEWDKL-GNLMRNKIIIDGRNLV 401
MF+E++++++ +++ I DGR ++
Sbjct: 419 MFKELDYERIHKRMLKPAFIFDGRRVL 445
>pir||A81290 probable UDPglucose 6-dehydrogenase (EC 1.1.1.22) Cj1441c
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6968870|emb|CAB73865.1| (AL139078) putative
UDP-glucose 6-dehydrogenase [Campylobacter jejuni]
Length = 393
Score = 110 bits (273), Expect = 3e-23
Identities = 102/366 (27%), Positives = 176/366 (47%), Gaps = 38/366 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSG-HDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVV 59
M+I ++G+GY+GL AI+F+ + ++V+ DI + ++ +N + I + I + + +
Sbjct: 1 MKIVIVGIGYVGLANAILFSKNNENEVVLLDIDENKIQSINNHKSPIKDKLIEKFFVQNI 60
Query: 60 SKGKLRATSDYNDLK-GADAFIICVQTPLSNGVP--DLTYLESAIKTIAKVIEKEALVVI 116
SK L ATS+ + AD +I T + D +E+ +K I K I + V+I
Sbjct: 61 SK--LHATSNIKEAYFNADFAVIATPTDYDEQLNFFDTRSIENVLKDI-KNINSKINVII 117
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKA 176
+STVP G T K +++ + + +PE + G + +Y SRII G
Sbjct: 118 KSTVPIGYT----KTIKQKFNMSN-----IVFSPEFLREGSALYDSLYPSRIIIG---DK 165
Query: 177 SILAEKLYRSFVKG------RIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGV 230
S+L + + F+K IF + AE VKL NT+ + + NE A K+ +
Sbjct: 166 SVLGKTIGDLFLKNIEKKNVDIFYMDSDEAESVKLFSNTYLAMRVGFFNEVDSYARKHNL 225
Query: 231 NVYEAIELANTHPRVK--IHRPGIGVGGHCLPKDPYLLLAN-VDEDLGLIRKARKINESM 287
N + I+ + R+ + P G GG+CLPKD LLAN + LI+ + NE
Sbjct: 226 NSADIIKGISADDRIGKYYNNPSFGYGGYCLPKDTKQLLANFYNIPNSLIKAIVETNEIR 285
Query: 288 PRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEK--DVKEVR 345
+F +L+ E ++ + L K ++D+ RNS ++ IK +++ E+
Sbjct: 286 KKFITQLILEKKPN--------ILGIYRLIMKQNSDNFRNSVIIDIIKYLQEYNSNIELI 337
Query: 346 TYDPYV 351
Y+P V
Sbjct: 338 IYEPLV 343
>emb|CAB43615.1| (AJ239004) uridine diphosphate glucose dehydrogenase [Streptococcus
pneumoniae]
Length = 412
Score = 107 bits (265), Expect = 2e-22
Identities = 109/387 (28%), Positives = 169/387 (43%), Gaps = 39/387 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+IAV G GY+GL A++ A H VI DI + VE +N+ + I + I + L E
Sbjct: 1 MKIAVTGTGYVGLSIAVLLAQH-HQVIAVDIIPEKVELINQRKSPIQDDYIEKYLAE--K 57
Query: 61 KGKLRATSDYNDL-KGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
L AT D + K AD +I T P N D + +ES I+T+ K +A++VI
Sbjct: 58 DLNLVATLDAKEAYKDADFVVIAAPTNYDPKKNFF-DTSAVESVIETVLKY-NPDAIMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV---S 173
+STVP G TE K + + +PE + + + +Y SRII G +
Sbjct: 116 KSTVPVGYTESARKKFQTEN---------ILFSPEFLRESKALYDNLYPSRIILGTDKNN 166
Query: 174 EKASILAEKLYRSFVKGRI------FLTTATTAEMVKLMENTFRDVNIALANEFAFLAHK 227
E+ +AE +G + T AE VKL NT+ + ++ NE +
Sbjct: 167 ERLVSVAETFAGLLQEGALKEDIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEM 226
Query: 228 YGVNVYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANV-DEDLGLIRKARKIN 284
G++ I+ PR+ H P G GG+CLPKD LLAN D LI + N
Sbjct: 227 KGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDVPEELIGAIVRSN 286
Query: 285 ESMPRFAAKLLFEALGEANVD---------PGDAVVLVLGLAYKGDTDDVRNSPALEFIK 335
+ F A + + + + D ++ + L K ++D+ R S +K
Sbjct: 287 STRKDFIADQVLKMVDSYDYSAHNVFNERVEKDIIIGIYRLTMKSNSDNFRQSSIQGIMK 346
Query: 336 IIEKDVKEVRTYDPYVNGTHTILEEAV 362
I+ V Y+P + T ++
Sbjct: 347 RIKAKGVRVVIYEPTLESGSTFFGSSI 373
>gb|AAD10180.1| (AF026471) Cps2K [Streptococcus pneumoniae]
Length = 412
Score = 106 bits (262), Expect = 5e-22
Identities = 108/388 (27%), Positives = 170/388 (42%), Gaps = 41/388 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERL--REV 58
M+IAV G GY+GL A++ S H V+ DI + VE +N+ + I + I + L +++
Sbjct: 1 MKIAVAGTGYVGLSIAVLL-SQQHQVMAVDIIPEKVELINQRKSPIQDDYIEKYLAKKDL 59
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVV 115
L A Y D AD +I T P N D + +ES I+T K +A++V
Sbjct: 60 NLVATLDAKEAYQD---ADFVVIAAPTNYDPKKNFF-DTSAVESVIETALKY-NPDAIMV 114
Query: 116 IESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV--- 172
I+STVP G TE K + + +PE + + + +Y SRII G
Sbjct: 115 IKSTVPVGYTESARKKFQTEN---------ILFSPEFLRESKALYDNLYPSRIILGTDKN 165
Query: 173 SEKASILAEKLYRSFVKGRI------FLTTATTAEMVKLMENTFRDVNIALANEFAFLAH 226
+E+ AE R +G + T AE VKL NT+ + ++ NE +
Sbjct: 166 NERLVSAAETFARLLQEGALKENIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSE 225
Query: 227 KYGVNVYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDEDLG-LIRKARKI 283
G++ I+ PR+ H P G GG+CLPKD LLAN ++ G LI +
Sbjct: 226 MTGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDIPGELIGAIVRS 285
Query: 284 NESMPRFAAKLLFEALGEANVD---------PGDAVVLVLGLAYKGDTDDVRNSPALEFI 334
N + F A + + + + D ++ + L K ++D+ R S +
Sbjct: 286 NSTRKDFIADQVLKMVDYYDYSAHNIFDERVEKDIIIGIYRLTMKSNSDNFRQSSIQGIM 345
Query: 335 KIIEKDVKEVRTYDPYVNGTHTILEEAV 362
K I+ V Y+P + T +V
Sbjct: 346 KRIKAKGVRVVIYEPTLESGSTFFGSSV 373
>sp|Q07172|UDG_STRPY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|1075776|pir||A46089 UDPglucose
6-dehydrogenase (EC 1.1.1.22) - Streptococcus pyogenes
>gi|8569328|pdb|1DLI|A Chain A, The First Structure Of
Udp-Glucose Dehydrogenase (Udpgdh) Reveals The Catalytic
Residues Necessary For The Two-Fold Oxidation
>gi|295189|gb|AAA26899.1| (L08444) UDP-glucose
hydrogenase [Streptococcus pyogenes]
Length = 402
Score = 104 bits (258), Expect = 1e-21
Identities = 107/369 (28%), Positives = 170/369 (45%), Gaps = 33/369 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+IAV G GY+GL ++ S ++V DI V+K+N G++ I + I L+
Sbjct: 1 MKIAVAGSGYVGLSLGVLL-SLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKS--K 57
Query: 61 KGKLRATSDYNDL-KGADAFIICVQTPLSNGVP--DLTYLESAIKTIAKVIEKEALVVIE 117
+ ++AT D K A+ II T ++ + D ++E+ IK + V A ++I+
Sbjct: 58 QLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSV-NSHATLIIK 116
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE--- 174
ST+P G M + + + +PE + + + +Y SRII E
Sbjct: 117 STIPIGFITEMRQKFQTDR---------IIFSPEFLRESKALYDNLYPSRIIVSCEENDS 167
Query: 175 -KASILAEK---LYRSFVKGR---IFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHK 227
K AEK L +S K + + A+ AE VKL NT+ + +A NE A
Sbjct: 168 PKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAES 227
Query: 228 YGVNVYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKIN 284
+N + I+ + R+ +H P G GG+CLPKD LLAN + LI N
Sbjct: 228 RKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSN 287
Query: 285 ESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIE-KDVKE 343
+ AK + L E + VV V L K ++D+ R S + I I++ KD+K
Sbjct: 288 NVRKSYIAKQIINVLKEQ--ESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIK- 344
Query: 344 VRTYDPYVN 352
+ Y+P +N
Sbjct: 345 IIIYEPMLN 353
>emb|CAA79813.1| (Z21706) ORF7 [synthetic construct]
Length = 209
Score = 103 bits (254), Expect = 4e-21
Identities = 68/209 (32%), Positives = 113/209 (53%), Gaps = 12/209 (5%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
++IA+IGLGY+GLP A F V+G+D+ + ++ GI +E E LR+
Sbjct: 7 VKIAIIGLGYVGLPLAAEFGKI-RQVVGFDVNHKRILELKEGIDVNLETT-EEELRDA-- 62
Query: 61 KGKLRATSDYNDLKGADAFIICVQTPLSN-GVPDLTYLESAIKTIAKVIEKEALVVIEST 119
L TS ++++ + +II V TP+++ PDLT L A +T+ KV+ +VV EST
Sbjct: 63 -RHLTFTSSIDEIRECNFYIITVPTPINDYKQPDLTPLIMASETVGKVLRPGDIVVYEST 121
Query: 120 VPPGTTER-MAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASI 178
V PG TE +LE ++ + +DF+V ++PER+ PG L +I G + + +
Sbjct: 122 VYPGCTEEECVPILERMSAMTFNKDFFVGYSPERINPGDKKYRLTTIKKITSGSTAETAC 181
Query: 179 LAEKLYRSFVKGRIFLTTATTAEMVKLME 207
L +++YR + + T E +K+ E
Sbjct: 182 LVDEIYRQIITAGTYKT-----ESIKIAE 205
>pdb|1DLJ|A Chain A, The First Structure Of Udp-Glucose Dehydrogenase (Udpgdh)
Reveals The Catalytic Residues Necessary For The
Two-Fold Oxidation
Length = 402
Score = 101 bits (248), Expect = 2e-20
Identities = 106/369 (28%), Positives = 169/369 (45%), Gaps = 33/369 (8%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+IAV G GY+GL ++ S ++V DI V+K+N G++ I + I L+
Sbjct: 1 MKIAVAGSGYVGLSLGVLL-SLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKS--K 57
Query: 61 KGKLRATSDYNDL-KGADAFIICVQTPLSNGVP--DLTYLESAIKTIAKVIEKEALVVIE 117
+ ++AT D K A+ II T ++ + D ++E+ IK + V A ++I+
Sbjct: 58 QLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSV-NSHATLIIK 116
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE--- 174
ST+P G M + + + +PE + + + +Y SRII E
Sbjct: 117 STIPIGFITEMRQKFQTDR---------IIFSPEFLRESKALYDNLYPSRIIVSCEENDS 167
Query: 175 -KASILAEK---LYRSFVKGR---IFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHK 227
K AEK L +S K + + A+ AE VKL NT+ + +A NE A
Sbjct: 168 PKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAES 227
Query: 228 YGVNVYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKIN 284
+N + I+ + R+ +H P G GG+ LPKD LLAN + LI N
Sbjct: 228 RKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYSLPKDTKQLLANYNNIPQTLIEAIVSSN 287
Query: 285 ESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIE-KDVKE 343
+ AK + L E + VV V L K ++D+ R S + I I++ KD+K
Sbjct: 288 NVRKSYIAKQIINVLKEQ--ESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIK- 344
Query: 344 VRTYDPYVN 352
+ Y+P +N
Sbjct: 345 IIIYEPMLN 353
>gb|AAC43311.1| (U15171) UDP-glucose dehydrogenase [Streptococcus pneumoniae]
>gi|1095716|prf||2109359A UDP-glucose dehydrogenase
[Streptococcus pneumoniae]
Length = 394
Score = 100 bits (247), Expect = 3e-20
Identities = 100/384 (26%), Positives = 174/384 (45%), Gaps = 42/384 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERL--REV 58
M+IA+ G GY+GL A++ A H+V D+ +D VE +N + I + I + L +E+
Sbjct: 1 MKIAIAGSGYVGLSLAVLLAQH-HEVKVIDVIKDKVESINNRKSPIKDEAIEKYLVEKEL 59
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPLSNGVP----DLTYLESAIKTIAKVIEKEALV 114
+ L Y D++ A + TP + V D + +E+AIKT + + +
Sbjct: 60 NLEASLDPAHVYKDVEYA-----IIATPTNYDVDLNQFDTSSVEAAIKTCMEYNDT-CTI 113
Query: 115 VIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
VI+ST+P G T+ + + K D + +PE + + + +Y SRI+ G
Sbjct: 114 VIKSTIPEGYTKEVRE--------KFNTD-RIIFSPEFLRESKALYDNLYPSRIVVGTDL 164
Query: 175 KASILAEKLYR--SFVKGR-------IFLTTATTAEMVKLMENTFRDVNIALANEFAFLA 225
S L ++ ++ +KG I + AE+ KL NT+ +A NE +
Sbjct: 165 DDSELTKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVAYFNEIDTYS 224
Query: 226 HKYGVNVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANV-DEDLGLIRKARK 282
G+N I++ PR+ + P G GG+CLPKD L A+ D LI +
Sbjct: 225 EVKGLNPKTIIDIVCYDPRIGSDYNNPSFGYGGYCLPKDTKQLKASFRDVPENLITAVVQ 284
Query: 283 INESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVK 342
N++ + A A + +VV + L K D+D+ R+S ++ ++ K
Sbjct: 285 SNKTRKDYIA--------GAILAKQPSVVGIYRLIMKSDSDNFRSSAVKGVMERLDNYGK 336
Query: 343 EVRTYDPYVNGTHTILEEAVKGVD 366
E+ Y+P + + +K +D
Sbjct: 337 EIVIYEPTIECDTFMGYRVIKSLD 360
>emb|CAB05929.1| (Z83335) uridine diphosphate glucose dehydrogenase [Streptococcus
pneumoniae]
Length = 410
Score = 99.5 bits (244), Expect = 6e-20
Identities = 104/373 (27%), Positives = 166/373 (43%), Gaps = 39/373 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERL--REV 58
M+IAV G GY+GL AI+ A H V+ DI + VE +N+ + I + I + L +E+
Sbjct: 1 MKIAVAGTGYVGLFIAILLAQH-HQVVAVDIIPEKVELINKKKSPIQDDYIEKYLAEKEL 59
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVV 115
L A Y + AD +I T P N D + +E+ I+ + K +A+++
Sbjct: 60 NFVATLNAEEAYEN---ADFIVIAAPTNYDPKKNFF-DTSSVEAVIEAVMKY-NPDAIII 114
Query: 116 IESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE- 174
I+STVP G T+ + + LT + +PE + + + +Y SRII G +
Sbjct: 115 IKSTVPVGYTKSVRRKF--LTD-------NIMFSPEFLRESKALYDNLYPSRIIIGTDKD 165
Query: 175 ------KASILAEKLYRSFVKGRI--FLTTATTAEMVKLMENTFRDVNIALANEFAFLAH 226
A I + L VK I T AE VKL NT+ + ++ NE +
Sbjct: 166 DKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFNELDTYSE 225
Query: 227 KYGVNVYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANV-DEDLGLIRKARKI 283
G++ I+ PR+ H P G GG+CLPKD LLAN D +I +
Sbjct: 226 MKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQEMITAIVQS 285
Query: 284 NESMPRFAAKLLFEA----LGEANVDPGDAVVLVLG---LAYKGDTDDVRNSPALEFIKI 336
N + + A + + +G P +V+G L K ++D+ R S +K
Sbjct: 286 NRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNFRQSSIQGIMKR 345
Query: 337 IEKDVKEVRTYDP 349
++ + Y+P
Sbjct: 346 LKAKGVTIIIYEP 358
>sp|Q57346|UDG_STRPN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|1658317|emb|CAA87403.1| (Z47210) uridine
diphosphate glucose dehydrogenase [Streptococcus
pneumoniae]
Length = 394
Score = 98.3 bits (241), Expect = 1e-19
Identities = 99/384 (25%), Positives = 173/384 (44%), Gaps = 42/384 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERL--REV 58
M+IA+ G GY+GL A++ A H+V D+ +D VE +N + I + I + L +E+
Sbjct: 1 MKIAIAGSGYVGLSLAVLLAQH-HEVKVIDVIKDKVESINNRKSPIKDEAIEKYLVEKEL 59
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPLSNGVP----DLTYLESAIKTIAKVIEKEALV 114
+ L Y D++ A + TP + V D + +E+AIKT + + +
Sbjct: 60 NLEASLDPAHVYKDVEYA-----IIATPTNYDVDLNQFDTSSVEAAIKTCMEYNDT-CTI 113
Query: 115 VIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
VI+ST+P G T+ + + K D + +PE + + + +Y SRI+ G
Sbjct: 114 VIKSTIPEGYTKEVRE--------KFNTD-RIIFSPEFLRESKALYDNLYPSRIVVGTDL 164
Query: 175 KASILAEKLYR--SFVKGR-------IFLTTATTAEMVKLMENTFRDVNIALANEFAFLA 225
S L ++ ++ +KG I + AE+ KL NT+ + NE +
Sbjct: 165 DDSELTKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVRYFNEIDTYS 224
Query: 226 HKYGVNVYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANV-DEDLGLIRKARK 282
G+N I++ PR+ + P G GG+CLPKD L A+ D LI +
Sbjct: 225 EVKGLNPKTIIDIVCYDPRIGSYYNNPSFGYGGYCLPKDTKQLKASFRDVPENLITAVVQ 284
Query: 283 INESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVK 342
N++ + A A + +VV + L K D+D+ R+S ++ ++ K
Sbjct: 285 SNKTRKDYIA--------GAILAKQPSVVGIYRLIMKSDSDNFRSSAVKGVMERLDNYGK 336
Query: 343 EVRTYDPYVNGTHTILEEAVKGVD 366
E+ Y+P + + +K +D
Sbjct: 337 EIVIYEPTIECDTFMGYRVIKSLD 360
>gi|9632145 PBCV-1 UDP-glucose dehydrogenase [Paramecium bursaria Chlorella
virus 1] >gi|7431390|pir||T18111 probable UDPglucose
6-dehydrogenase (EC 1.1.1.22) - Chlorella virus PBCV-1
>gi|2447087|gb|AAC96945.1| (U42580) PBCV-1 UDP-glucose
dehydrogenase [Paramecium bursaria Chlorella virus 1]
Length = 389
Score = 97.5 bits (239), Expect = 2e-19
Identities = 100/367 (27%), Positives = 163/367 (44%), Gaps = 45/367 (12%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
RIAV+G GY+G A++ A ++VI DI D V+ + + I + EI E L
Sbjct: 3 RIAVVGCGYVGTACAVLLAQK-NEVIVLDISEDRVQLIKNKKSPIEDKEIEEFLE--TKD 59
Query: 62 GKLRATSDYNDLKGADAFIICVQTPLSNGVPDLTY----LESAIKTIAKVIEKEALVVIE 117
L AT+D L +A + + TP V + +E+ I + K + +VI+
Sbjct: 60 LNLTATTD-KVLAYENAEFVIIATPTDYDVVTRYFNTKSVENVIGDVIKNTQTHPTIVIK 118
Query: 118 STVPPGTTERMAKLLEELTGLKEGEDFY-VAHAPERVMPGRIFKELVYNSRIIGGVSEKA 176
ST+P G +++ +E D+ + +PE + GR + +Y SRII G
Sbjct: 119 STIPIGFVDKV----------REQFDYQNIIFSPEFLREGRALYDNLYPSRIIVGDD--- 165
Query: 177 SILAEKLYRSFVKGRI-----FLTTATT-AEMVKLMENTFRDVNIALANEFAFLAHKYGV 230
S +A K V+G LT T AE VKL NT+ + +A NE A +G+
Sbjct: 166 SPIALKFANLLVEGSKTPLAPVLTMGTREAEAVKLFSNTYLAMRVAYFNELDTFAMSHGM 225
Query: 231 NVYEAIELANTHPRV--KIHRPGIGVGGHCLPKDPYLLLANVD----EDLGLIRKARKIN 284
N E I+ PR+ P G G +C PKD LLAN + + +G I ++ +
Sbjct: 226 NAKEIIDGVTLEPRIGQGYSNPSFGYGAYCFPKDTKQLLANFEGVPQDIIGAIVESNETR 285
Query: 285 ESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEV 344
+ E + + V V LA K +D+ R+S ++ ++ + +
Sbjct: 286 K-----------EVIVSEVENRFPTTVGVYKLAAKAGSDNFRSSAIVDIMERLANKGYHI 334
Query: 345 RTYDPYV 351
+ ++P V
Sbjct: 335 KIFEPTV 341
>emb|CAA78147.1| (Z12159) uridine diphosphate glucose dehydrogenase [Streptococcus
pneumoniae] >gi|1586508|prf||2204223D UDP-Glucose
dehydrogenase [Streptococcus pneumoniae]
Length = 394
Score = 94.4 bits (231), Expect = 2e-18
Identities = 98/384 (25%), Positives = 171/384 (44%), Gaps = 42/384 (10%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERL--REV 58
M+IA+ G GY+GL A++ A H+V D+ +D VE +N + I + I + L +E+
Sbjct: 1 MKIAIAGSGYVGLSLAVLLAQH-HEVKVIDVIKDKVESINNRKSPIKDEAIEKYLVEKEL 59
Query: 59 VSKGKLRATSDYNDLKGADAFIICVQTPLSNGVP----DLTYLESAIKTIAKVIEKEALV 114
+ L Y D++ A + TP + V D + +E+AIKT + + +
Sbjct: 60 NLEASLDPAHVYKDVEYA-----IIATPTNYDVDLNQFDTSSVEAAIKTCMEYNDT-CTI 113
Query: 115 VIESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSE 174
VI+ST+P G T+ + K D + +PE + + + +Y SRI+ G
Sbjct: 114 VIKSTIPEGYTKEVRD--------KFNTD-RIIFSPEFLRESKALYDNLYPSRIVVGTDL 164
Query: 175 KASILAEKLYR--SFVKGR-------IFLTTATTAEMVKLMENTFRDVNIALANEFAFLA 225
S L ++ ++ +KG I + AE+ KL NT+ + NE +
Sbjct: 165 DDSELTKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVRYFNEIDTYS 224
Query: 226 HKYGVNVYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANV-DEDLGLIRKARK 282
+N I++ PR+ + P G GG+CLPKD L A+ D LI +
Sbjct: 225 EVKELNPKTIIDIVCYDPRIGSYYNNPSFGYGGYCLPKDTKQLKASFRDVPENLITAVVQ 284
Query: 283 INESMPRFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVK 342
N++ + A A + +VV + L K D+D+ R+S ++ ++ K
Sbjct: 285 SNKTRKDYIA--------GAILAKQPSVVGIYRLIMKSDSDNFRSSAVKGVMERLDNYGK 336
Query: 343 EVRTYDPYVNGTHTILEEAVKGVD 366
E+ Y+P + + +K +D
Sbjct: 337 EIVIYEPTIECDTFMGYRVIKSLD 360
>pir||S69821 NDP-sugar dehydrogenase homolog lmbL - Streptomyces lincolnensis
>gi|581693|emb|CAA55758.1| (X79146) lmbL [Streptomyces
lincolnensis]
Length = 436
Score = 88.9 bits (217), Expect = 9e-17
Identities = 99/412 (24%), Positives = 161/412 (39%), Gaps = 31/412 (7%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
R+AV GL ++G A + G V+ Y+ + + EP +GE LR + +
Sbjct: 7 RVAVCGLWHLGSTAAAGLLTHGRAVVAYEPQEHCGRRA-AATPPTGEPGVGEVLRRGLRE 65
Query: 62 GKLRATSDYNDLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
G+LR + ++ + + ++G D L A+ A+ A + + S V
Sbjct: 66 GRLRVADALAEWARNALCVLAYDSAVDADGGVDDARLAQAVAAFARHAPAGATLAVLSQV 125
Query: 121 PPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILA 180
P T + L L D + H PE + GR + V +R++ G E+ + A
Sbjct: 126 PAHTQCAWRRTL-----LAHRPDVNLVHIPENLRLGRAMDDFVAPARLVVGAEERCT--A 178
Query: 181 EKLYRS-FVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELA 239
E+ RS F + T T AE+VK N + + ++ NE +LA G + L
Sbjct: 179 ERTARSLFPRATPAYVTLTEAELVKHATNAYLGMCVSFGNELGWLAAHLGADPQVVARLL 238
Query: 240 NTHPRVKIHR---PGIGVGGHCLPKDPYLLLANVDEDLG---LIRKARKINESMPRFAAK 293
PRV PG G L +D + L+ + G +N+ F
Sbjct: 239 KADPRVADAAPLLPGAAFSGATLRRD-LVALSRIGAKWGRPEFFDTVLTVNDRHAAFPLD 297
Query: 294 LLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNG 353
LL LG D + + GL YK +R+S L ++ + D EV YDP
Sbjct: 298 LLGAELGNLK----DRRIALAGLTYKAGHATLRDSLPLRLVRTLLTDGAEVVAYDPVAED 353
Query: 354 --------THTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDG 397
L +AV +A ++A +W L R +++DG
Sbjct: 354 LPDDVGARRAATLADAVPAPNACLVAAALPELDGADWAGLRPAAR--LVVDG 403
>pir||S44959 lmbL protein - Streptomyces lincolnensis
Length = 436
Score = 88.9 bits (217), Expect = 9e-17
Identities = 99/412 (24%), Positives = 161/412 (39%), Gaps = 31/412 (7%)
Query: 2 RIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVSK 61
R+AV GL ++G A + G V+ Y+ + + EP +GE LR + +
Sbjct: 7 RVAVCGLWHLGSTAAAGLLTHGRAVVAYEPQEHCGRRA-AATPPTGEPGVGEVLRRGLRE 65
Query: 62 GKLRATSDYNDLKGADAFIICVQTPL-SNGVPDLTYLESAIKTIAKVIEKEALVVIESTV 120
G+LR + ++ + + ++G D L A+ A+ A + + S V
Sbjct: 66 GRLRVADALAEWARNALCVLAYDSAVDADGGVDDARLAQAVAAFARHAPAGATLAVLSQV 125
Query: 121 PPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKASILA 180
P T + L L D + H PE + GR + V +R++ G E+ + A
Sbjct: 126 PAHTQCAWRRTL-----LAHRPDVNLVHIPENLRLGRAMDDFVAPARLVVGAEERCT--A 178
Query: 181 EKLYRS-FVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIELA 239
E+ RS F + T T AE+VK N + + ++ NE +LA G + L
Sbjct: 179 ERTARSLFPRATPAYVTLTEAELVKHATNAYLGMCVSFGNELGWLAAHLGADPQVVARLL 238
Query: 240 NTHPRVKIHR---PGIGVGGHCLPKDPYLLLANVDEDLG---LIRKARKINESMPRFAAK 293
PRV PG G L +D + L+ + G +N+ F
Sbjct: 239 KADPRVADAAPLLPGAAFSGATLRRD-LVALSRIGAKWGRPEFFDTVLTVNDRHAAFPLD 297
Query: 294 LLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNG 353
LL LG D + + GL YK +R+S L ++ + D EV YDP
Sbjct: 298 LLGAELGNLK----DRRIALAGLTYKAGHATLRDSLPLRLVRTLLTDGAEVVAYDPVAED 353
Query: 354 --------THTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDG 397
L +AV +A ++A +W L R +++DG
Sbjct: 354 LPDDVGARRAATLADAVPAPNACLVAAALPELDGADWAGLRPAAR--LVVDG 403
>pir||S38583 hypothetical protein - rice >gi|414707|emb|CAA53449.1| (X75814)
22.4% identity in277 aa overlap with P1; ALGO_PSEAE
(ACP11759) [Oryza sativa]
Length = 338
Score = 85.8 bits (209), Expect = 8e-16
Identities = 89/280 (31%), Positives = 132/280 (46%), Gaps = 26/280 (9%)
Query: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
M+I + G GY+GL ++ A + H+V+ DI V +N I+ IV+ EI + L+
Sbjct: 1 MKITISGTGYVGLSNGLLIAQN-HEVVALDILPSRVAMLNDRISPIVDKEIQQFLQS--D 57
Query: 61 KGKLRATSDYNDL-KGADAFIICVQT---PLSNGVPDLTYLESAIKTIAKVIEKEALVVI 116
K AT D N+ + AD II T P +N + + +ES IK + + I A++VI
Sbjct: 58 KIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYF-NTSSVESVIKDVVE-INPYAVMVI 115
Query: 117 ESTVPPGTTERMAKLLEELTGLKEGEDFYVAHAP----ERVMPGRIFKELVYNSRIIGGV 172
+STVP G T A+ T LK + ++P ERV P I L S +
Sbjct: 116 KSTVPVGFT---AERCIRNTALK------ILYSPLNFSERVKPFTIISILHVFSSVSVQN 166
Query: 173 SEKASILAEKLYRSFVKGRIFLTTATTAEMVKLMEN-TFRDVNIALANEFAFLAHKYGVN 231
++ S+L + R R L T + + ++ T+R L N A + G+N
Sbjct: 167 AQNVSLLCYRKARLSKISRCCLPTPLKQKRLNFLQTRTWRCAWRTLTNWIA-MPESLGLN 225
Query: 232 VYEAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLAN 269
+ IE PR+ H P G GG+CLPKD LLAN
Sbjct: 226 SRQIIEGVCXDPRIGNHYNNPSFGYGGYCLPKDTKQLLAN 265
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.141 0.398
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 153599184
Number of Sequences: 2977
Number of extensions: 6482998
Number of successful extensions: 18424
Number of sequences better than 1.0e-10: 113
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 17931
Number of HSP's gapped (non-prelim): 119
length of query: 418
length of database: 189,106,746
effective HSP length: 57
effective length of query: 361
effective length of database: 154,992,987
effective search space: 55952468307
effective search space used: 55952468307
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)