BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0380 (glyS) DE:glycyl-tRNA synthetase (glyS)
(571 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9V176|SYG_PYRAB GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 1164 0.0
sp|O59235|SYG_PYRHO GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 1080 0.0
sp|Q57681|SYG_METJA GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 626 e-178
sp|O27874|SYG_METTH GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 602 e-171
gi|11498521 glycyl-tRNA synthetase (glyS) [Archaeoglobus fulgidu... 545 e-154
sp|Q9YBF8|SYG_AERPE GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 513 e-144
gb|AAK40768.1| Glycyl-tRNA synthetase (glyS) [Sulfolobus solfata... 463 e-129
gb|AAG20454.1| (AE005117) glycine-tRNA synthetase; GlyS [Halobac... 444 e-123
gb|AAF49668.1| (AE003532) CG6778 gene product [Drosophila melano... 407 e-112
sp|Q10039|SYG_CAEEL PROBABLE GLYCYL-TRNA SYNTHETASE (GLYCINE--TR... 401 e-110
gb|AAA86443.1| (U09510) glycyl-tRNA synthetase [Homo sapiens] 388 e-107
gi|6996010 glycyl-tRNA synthetase; GlyRS; glycine tRNA ligase [H... 388 e-107
pir||A55314 glycine--tRNA ligase (EC 6.1.1.14) precursor [valida... 388 e-107
gi|11420984 glycyl-tRNA synthetase [Homo sapiens] 388 e-107
sp|Q04451|SYG_BOMMO GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 386 e-106
sp|Q10179|SYG_SCHPO PUTATIVE GLYCYL-TRNA SYNTHETASE (GLYCINE--TR... 384 e-105
sp|O23627|SYG_ARATH GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 380 e-104
pir||A46636 glycine--tRNA ligase (EC 6.1.1.14) - silkworm 376 e-103
gi|6325338 Ypr081cp [Saccharomyces cerevisiae] >gi|2132408|pir||... 372 e-102
gi|6319597 Glycyl-tRNA synthase; Grs1p [Saccharomyces cerevisiae... 363 2e-99
gb|AAG38542.1|AF309805_7 (AF309805) glycyl tRNA synthetase [Pneu... 329 5e-89
emb|CAC11352.1| (AL445063) glycyl-tRNA synthetase related [Therm... 284 2e-75
pir||C75320 glycyl-tRNA synthetase - Deinococcus radiodurans (st... 258 1e-67
sp|Q9RSR5|SYG_DEIRA GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 258 1e-67
gb|AAG10609.1|AC008030_9 (AC008030) Putative glycyl-tRNA synthe... 249 5e-65
gb|AAC71652.1| (AC004976) glycyl tRNA synthetase [Homo sapiens] 213 5e-54
sp|Q9PPZ7|SYG_UREPA GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 207 3e-52
sp|O51344|SYG_BORBU GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 203 3e-51
sp|Q9L2H9|SYG_STRCO GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 199 9e-50
sp|O65932|SYG_MYCTU GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 190 3e-47
emb|CAB40582.1| (AJ010128) glycyl-tRNA synthetase [Bacillus cereus] 180 4e-44
sp|O83678|SYG_TREPA GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 177 3e-43
sp|P75425|SYG_MYCPN GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 169 7e-41
pdb|1ATI|A Chain A, Crystal Structure Of Glycyl-Trna Synthetase ... 168 1e-40
sp|P56206|SYG_THETH GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 168 1e-40
pir||S58522 glycine--tRNA ligase (EC 6.1.1.14) - Thermus aquaticus 168 2e-40
sp|P47493|SYG_MYCGE GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE... 167 4e-40
pdb|1B76|A Chain A, Glycyl-Trna Synthetase From Thermus Thermoph... 147 3e-34
emb|CAA10903.1| (AJ222643) Glycyl-tRNA synthetase [Thermus therm... 140 3e-32
gb|AAB70033.1|AAB70033 (AC002534) similar to glycyl tRNA synthet... 122 1e-26
gb|AAC23791.1| (AC005154) glycyl-tRNA synthetase; similar to pro... 83 8e-15
>sp|Q9V176|SYG_PYRAB GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|7437698|pir||C75174 glycyl-tRNA synthetase (glys)
PAB0380 - Pyrococcus abyssi (strain Orsay)
>gi|5457984|emb|CAB49474.1| (AJ248284) glycyl-tRNA
synthetase (glyS) [Pyrococcus abyssi]
Length = 571
Score = 1164 bits (2979), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 1 MGERFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREG 60
MGERFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREG
Sbjct: 1 MGERFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREG 60
Query: 61 FFEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEM 120
FFEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEM
Sbjct: 61 FFEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEM 120
Query: 121 TKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAF 180
TKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAF
Sbjct: 121 TKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAF 180
Query: 181 ARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLR 240
ARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLR
Sbjct: 181 ARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLR 240
Query: 241 LYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLP 300
LYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLP
Sbjct: 241 LYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLP 300
Query: 301 EERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVK 360
EERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVK
Sbjct: 301 EERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVK 360
Query: 361 RLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDGYELSKDDFI 420
RLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDGYELSKDDFI
Sbjct: 361 RLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDGYELSKDDFI 420
Query: 421 IKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAPIEVAVL 480
IKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAPIEVAVL
Sbjct: 421 IKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAPIEVAVL 480
Query: 481 PLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDG 540
PLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDG
Sbjct: 481 PLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDG 540
Query: 541 TVTIRDRDTREQIRVKLEDVPRKLKELIFGS 571
TVTIRDRDTREQIRVKLEDVPRKLKELIFGS
Sbjct: 541 TVTIRDRDTREQIRVKLEDVPRKLKELIFGS 571
>sp|O59235|SYG_PYRHO GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|7437695|pir||F71040 glycine--tRNA ligase (EC
6.1.1.14) - Pyrococcus horikoshii
>gi|3258043|dbj|BAA30726.1| (AP000006) 570aa long
hypothetical glycyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 570
Score = 1080 bits (2763), Expect = 0.0
Identities = 513/570 (90%), Positives = 552/570 (96%)
Query: 1 MGERFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREG 60
M +FDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIE+KIREAFIREG
Sbjct: 1 MNGKFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIERKIREAFIREG 60
Query: 61 FFEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEM 120
FFEIETPDITPEQVFIASGHVEKFVDP+VECKKCG RFRADHLIEE LGIDVEGKSAEEM
Sbjct: 61 FFEIETPDITPEQVFIASGHVEKFVDPVVECKKCGMRFRADHLIEEFLGIDVEGKSAEEM 120
Query: 121 TKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAF 180
++IIREH +KCPECGGEL DVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAF
Sbjct: 121 SRIIREHGLKCPECGGELSDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAF 180
Query: 181 ARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLR 240
ARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAE EIFFNPNETEHPHF+EVKHEKL+
Sbjct: 181 ARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEAEIFFNPNETEHPHFNEVKHEKLK 240
Query: 241 LYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLP 300
LYPIENQLK+LG +E+TAEEAVK+GY+MN+FFAYY+VMIKKILLDIGIPEDKIRFRQQLP
Sbjct: 241 LYPIENQLKELGEVEVTAEEAVKRGYVMNSFFAYYMVMIKKILLDIGIPEDKIRFRQQLP 300
Query: 301 EERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVK 360
EERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPK+VK
Sbjct: 301 EERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKVVK 360
Query: 361 RLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDGYELSKDDFI 420
R++VSLNMK VGPKLK DAK+INE I++M ++EL +LVK LNE+GK+ I+GYELSK+DFI
Sbjct: 361 RIQVSLNMKKVGPKLKADAKKINEIIKSMDQKELEKLVKDLNEKGKVTIEGYELSKEDFI 420
Query: 421 IKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAPIEVAVL 480
+KEVEEK+TGEKI+PHVLEPSFGIDRPFYLLLENSLT+DEDGRIYLKIKKDMAPIEVAVL
Sbjct: 421 VKEVEEKITGEKIVPHVLEPSFGIDRPFYLLLENSLTVDEDGRIYLKIKKDMAPIEVAVL 480
Query: 481 PLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDG 540
PLVAKEPLT IAY+++R LQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVT+DNQTP DG
Sbjct: 481 PLVAKEPLTTIAYEIYRTLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTVDNQTPEDG 540
Query: 541 TVTIRDRDTREQIRVKLEDVPRKLKELIFG 570
TVTIRDRDTREQIRVK+E++PRKLKELIFG
Sbjct: 541 TVTIRDRDTREQIRVKIEELPRKLKELIFG 570
>sp|Q57681|SYG_METJA GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|2127942|pir||E64328 glycine--tRNA ligase (EC
6.1.1.14) - Methanococcus jannaschii
>gi|1499005|gb|AAB98213.1| (U67478) glycyl-tRNA
synthetase (glyS) [Methanococcus jannaschii]
Length = 577
Score = 626 bits (1596), Expect = e-178
Identities = 308/571 (53%), Positives = 409/571 (70%), Gaps = 11/571 (1%)
Query: 6 DKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI-REGFFEI 64
D YE + DL +RRG+ W SFEIYGG GF DYGPLG +K I K RE +I +EGF+EI
Sbjct: 4 DIYEKIMDLAKRRGYLWSSFEIYGGIAGFVDYGPLGCLLKNNIISKFREQYIIKEGFYEI 63
Query: 65 ETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEMTKII 124
E+P +TP +V ASGHV+ F DPIVECK C FRADHLIEE + +D EGK+ +E+ ++I
Sbjct: 64 ESPTVTPYEVLKASGHVDNFTDPIVECKNCLESFRADHLIEEFVDVDTEGKTLKELDELI 123
Query: 125 REHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFARNK 184
R+HNI+CP+CGGELG+V FNLMF T IGP + Y+RPETAQGIF+ F+RL F RNK
Sbjct: 124 RKHNIRCPKCGGELGEVKKFNLMFVTSIGPGGKRTGYMRPETAQGIFIQFRRLAQFFRNK 183
Query: 185 LPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPI 244
LPFGV QIGK+YRNEISPRQG+IRLREFTQAE+E F +P EH FD VK E + L P
Sbjct: 184 LPFGVVQIGKSYRNEISPRQGVIRLREFTQAEIEYFVHPERKEHEKFDLVKDEVVPLLPA 243
Query: 245 ENQL-----KDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQL 299
E Q+ D +I+++ EAV+KG + + AY++ + K+ L IGI +DKIRFRQ L
Sbjct: 244 ERQMDENLSDDEKVIKISIGEAVEKGIIRHQTIAYFIALTKRFLEAIGIDKDKIRFRQHL 303
Query: 300 PEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIV 359
P E AHY+ D WDAE+Y+ERFGW+ECVG+A RTDYDL H SG +L+V + D+ + +
Sbjct: 304 PNEMAHYAIDCWDAEIYTERFGWIECVGIADRTDYDLRSHSAHSGVELSVFVELDEEREI 363
Query: 360 KRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIV--IDG--YELS 415
+ +++LN K VG KKD K I I +SE+E E VK + +GK++ IDG +E+
Sbjct: 364 ETYEINLNYKVVGKIFKKDTKAIEAYINNLSEKEKEEFVKNIENDGKVIINIDGKEFEIL 423
Query: 416 KDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAPI 475
KD IK+V++ + GEK+IPHV+EPS+GIDR Y LLE+S +ED R+YL +K +API
Sbjct: 424 KDYVEIKKVKKVIKGEKVIPHVIEPSYGIDRITYCLLEHSYREEED-RVYLDLKPSIAPI 482
Query: 476 EVAVLPLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQ 535
+ VLPLV K+ + KIA ++ + L++ G I YD+ +IG+RYMR DEIG P+C+T+D Q
Sbjct: 483 KAYVLPLVNKDDMPKIAKEIEQMLRENGIIAEYDDSGAIGRRYMRADEIGVPFCITVDGQ 542
Query: 536 TPIDGTVTIRDRDTREQIRVKLEDVPRKLKE 566
T D TVT+R+R+TREQ+RVK++++ LKE
Sbjct: 543 TLEDRTVTVRERNTREQVRVKIDELVDYLKE 573
>sp|O27874|SYG_METTH GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|7437697|pir||H69113 glycine--tRNA ligase (EC
6.1.1.14) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622981|gb|AAB86312.1| (AE000937)
glycyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 565
Score = 602 bits (1536), Expect = e-171
Identities = 289/562 (51%), Positives = 397/562 (70%), Gaps = 6/562 (1%)
Query: 8 YEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI-REGFFEIET 66
+E + R+RGF W SFEIY G GF DYGPLGAT+K KI + RE ++ REGF+EIE+
Sbjct: 6 HERTMTVARKRGFLWSSFEIYSGVAGFVDYGPLGATLKNKIMNRWREFYVVREGFYEIES 65
Query: 67 PDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEMTKIIRE 126
P I PE+ ASGHV+ F DP+ +CK+C +RADH+IE+ G DVEG +E+T+II +
Sbjct: 66 PTIMPEEALKASGHVDHFNDPMTQCKECMDVYRADHIIEDATGRDVEGLENQELTEIISD 125
Query: 127 HNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFARNKLP 186
I+CP CGG L V+ +NLMF+T IG K YLRPETAQGIF+ FKRL F RN+LP
Sbjct: 126 EGIRCPRCGGHLTHVWSYNLMFQTLIGARGKKTGYLRPETAQGIFIPFKRLLRFFRNRLP 185
Query: 187 FGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPIEN 246
FGV Q+GK+YRNEISPRQG+IRLREFTQAE EIF +P HP F+EVK + LRLYP
Sbjct: 186 FGVVQLGKSYRNEISPRQGVIRLREFTQAEAEIFVDPEHKTHPDFEEVKEDILRLYPAGR 245
Query: 247 QLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEERAHY 306
Q+++ G +++TA EA++ G + + Y+L + K+ L+DIGIPED +RFRQ LP E AHY
Sbjct: 246 QMEESGTVDMTAAEALEAGVISSEVLTYHLCLAKRFLMDIGIPEDALRFRQHLPSEMAHY 305
Query: 307 SADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVKRLKVSL 366
+ D WD E +++ +GW+E +G+A RTDYDL H + SG DL V I YD+P+ +++ V
Sbjct: 306 AIDCWDVEAFTDSYGWIEIIGIADRTDYDLRSHSQHSGEDLRVFIEYDEPRRIRKRAVKP 365
Query: 367 NMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDG-YELSKDDFIIKEVE 425
+M +GPK +KDA RI A+SE ++ E+ K L+EEG+ +++G +E+ DD ++VE
Sbjct: 366 DMGKLGPKFRKDAARI---ASALSEVDVEEIEKALDEEGRFILEGEFEILPDDVSFEDVE 422
Query: 426 EKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAPIEVAVLPLVAK 485
E VTG K+ PHV+EPSFGIDR Y LL +SL +D+ R Y ++ +AP+EV VLPLV +
Sbjct: 423 EVVTGRKVYPHVIEPSFGIDRIIYTLLLHSL-VDDGERTYFRLPPHVAPVEVTVLPLVNR 481
Query: 486 EPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDGTVTIR 545
E + A ++ R L++ GFI +D +IG+RY R DEIG P+ VT+D++T DGTVT+R
Sbjct: 482 EEMVMTALEIERNLRRSGFIAEFDSSGTIGRRYARADEIGVPFAVTVDHETLEDGTVTLR 541
Query: 546 DRDTREQIRVKLEDVPRKLKEL 567
+RD Q+RVK+E++ L++L
Sbjct: 542 NRDDCSQVRVKIEELVPTLEKL 563
>gi|11498521 glycyl-tRNA synthetase (glyS) [Archaeoglobus fulgidus]
>gi|3334354|sp|O29346|SYG_ARCFU GLYCYL-TRNA SYNTHETASE
(GLYCINE--TRNA LIGASE) (GLYRS) >gi|7437696|pir||D69364
glycyl-tRNA synthetase (glyS) homolog - Archaeoglobus
fulgidus >gi|2649683|gb|AAB90321.1| (AE001040)
glycyl-tRNA synthetase (glyS) [Archaeoglobus fulgidus]
Length = 570
Score = 545 bits (1390), Expect = e-154
Identities = 281/564 (49%), Positives = 391/564 (68%), Gaps = 21/564 (3%)
Query: 11 LQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAF-IREGFFEIETPDI 69
+ +++ RRGF W SFEIYGG GF DY PLG ++RKIE R+ F I E EI+TP I
Sbjct: 6 IMEMLIRRGFLWQSFEIYGGMAGFIDYAPLGNNLRRKIENIWRKYFVINERAAEIDTPTI 65
Query: 70 TPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEMTKIIREHNI 129
E+VFIASGH F D +EC+ CG +RADH ++E LGI+V+ ++ E + +++ +++
Sbjct: 66 GIEEVFIASGHATSFTDVAIECENCGRVYRADHYVKEKLGIEVD-ETVEAVKEVMEVYDL 124
Query: 130 KCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFARNKLPFGV 189
KC ECGG D NLMF T IGP K KK YLRPETAQG+FV+FKRL F R KLPFGV
Sbjct: 125 KC-ECGGRFKDPAPMNLMFSTTIGPGKGKKGYLRPETAQGMFVDFKRLANFFREKLPFGV 183
Query: 190 FQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPIENQLK 249
QIG+AYRNEISPRQG+IRLREF QAE+E F +P E +HPHF + ++L K
Sbjct: 184 AQIGRAYRNEISPRQGVIRLREFNQAELEFFVHPGEKKHPHFSLYAKDVVKLVD-----K 238
Query: 250 DLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEERAHYSAD 309
E+T EEAV+KG + N AY++ ++ LL+IGI ++K+RFRQ ERAHY+ D
Sbjct: 239 FDSQHEITLEEAVEKGIIANQILAYFIGKTRRFLLEIGIKDEKLRFRQHKDVERAHYATD 298
Query: 310 TWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVKRLKVSLNMK 369
WDAEV + +GW+E VG+A RT+YDL RH K SG DL+V + Y++P VKR K+ +
Sbjct: 299 CWDAEVLTS-YGWIEVVGIADRTNYDLKRHSKFSGEDLSVFVPYEEPVKVKRRKIVPILS 357
Query: 370 SVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDG--YELSKDDFIIKEVEEK 427
+GP+ ++ AK++ E ++A++ V+ +E ++ +DG +++K+ F I+EVEE+
Sbjct: 358 KLGPEFRQKAKKVAEALEALN-------VEADLDEVEVEVDGEKVKVTKEFFEIQEVEEE 410
Query: 428 VTGEKIIPHVLEPSFGIDRPFYLLLENSL---TIDEDGRIYLKIKKDMAPIEVAVLPLVA 484
VTGEK+IPHV+EPSFG+DR Y +LE++ +D + R L++K+ ++PIEVAVLPL++
Sbjct: 411 VTGEKVIPHVIEPSFGLDRITYSVLEHAFDKDVVDGEERRVLRLKRWVSPIEVAVLPLLS 470
Query: 485 KEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDGTVTI 544
+EP ++ + L++EG YD+ SIG+RY R+DEIGTP+CVT+D+QT D TVTI
Sbjct: 471 REPFESKGMEIVQMLREEGIFTDYDDSGSIGRRYRRFDEIGTPFCVTVDHQTFEDETVTI 530
Query: 545 RDRDTREQIRVKLEDVPRKLKELI 568
RDRDT Q+RVKL ++P LKEL+
Sbjct: 531 RDRDTTAQVRVKLGELPSILKELL 554
>sp|Q9YBF8|SYG_AERPE GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|7437699|pir||C72544 probable glycyl-tRNA synthetase
APE1639 - Aeropyrum pernix (strain K1)
>gi|5105327|dbj|BAA80640.1| (AP000062) 583aa long
hypothetical glycyl-tRNA synthetase [Aeropyrum pernix]
Length = 583
Score = 513 bits (1307), Expect = e-144
Identities = 270/571 (47%), Positives = 366/571 (63%), Gaps = 12/571 (2%)
Query: 6 DKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI---REGFF 62
D +E L ++ +RRGF W S+EIYGG GFYD+GPLG +KR+I +K R F+ ++
Sbjct: 4 DLFEKLVEIGKRRGFFWPSYEIYGGVAGFYDWGPLGHLLKRRIIEKWRRYFVLMHQDHVV 63
Query: 63 EIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEMTK 122
EIETP I PE+V+IASGHVE F DPIV C CG FRADHL+EE LGI+ EG S E+ +
Sbjct: 64 EIETPVIGPEKVYIASGHVEHFTDPIVRCTSCGRTFRADHLVEEALGINAEGLSVSELDR 123
Query: 123 IIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFAR 182
IIRE ++CP C GELG V FNL+F T IGPY+ YLRPE AQGIFV FKR+ R
Sbjct: 124 IIRERGLRCPVCQGELGRVETFNLLFRTQIGPYEGSVGYLRPELAQGIFVAFKRVYEAMR 183
Query: 183 NKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNET--EHPHFDEVKHEKLR 240
+++P G+ Q+G+ RNEISPRQ ++RLREFT E+E F +P + P F + KL
Sbjct: 184 SRIPLGIAQVGRVGRNEISPRQALVRLREFTIMEMEYFIDPEDQWGSCPFFHRMADSKLP 243
Query: 241 LYPIENQLKDLGMIE-LTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQL 299
+ E + + E EEAV +G +++ Y++ + + + D+G+P D I F ++
Sbjct: 244 ILTYEAKRRGEEKPESFKLEEAVNEGVVISPCLGYWMAVGMRFVEDLGVPSDSIMFEEKG 303
Query: 300 PEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIV 359
PEERAHYS+ T+D V R+GW+E G +YR DYDLSRHMK SG DLT Y KP +V
Sbjct: 304 PEERAHYSSQTFDQLVKVSRWGWIEVAGHSYRGDYDLSRHMKYSGQDLTAFKPYPKPIVV 363
Query: 360 KRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDGYELSKDDF 419
K+ +V ++ ++G LK AK + E++ M E EL ++L + V+ G EL
Sbjct: 364 KKRRVVVDKAAIGRALKSRAKTVLEELGRMGEGEL----ERLAASNRAVVAGVELPPGSL 419
Query: 420 IIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAPIEVAV 479
I EVEEKV+G + +PHV+EPSFG DR Y+ LE + + +GR+ L +D+AP++ V
Sbjct: 420 RIVEVEEKVSGRRFVPHVVEPSFGTDRNVYVALEYAYR-EVEGRVVLAFPRDIAPVQAVV 478
Query: 480 LPLVAK-EPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPI 538
LPLV E L + A ++ L + GF V YD+ SIG+RY R DEIG P VTID QT
Sbjct: 479 LPLVENDEKLVERARMVYETLVEAGFTVYYDDSGSIGRRYARADEIGVPAAVTIDYQTLE 538
Query: 539 DGTVTIRDRDTREQIRVKLEDVPRKLKELIF 569
DGTVT+RDRDT Q+R+ ++V KL+ I+
Sbjct: 539 DGTVTLRDRDTWRQVRIGADEVVDKLRRFIY 569
>gb|AAK40768.1| Glycyl-tRNA synthetase (glyS) [Sulfolobus solfataricus]
Length = 574
Score = 463 bits (1178), Expect = e-129
Identities = 258/576 (44%), Positives = 363/576 (62%), Gaps = 23/576 (3%)
Query: 1 MGERFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREG 60
M E DK + DL +RRG W S+EIYGG GFYD GP+G IK +I + R+ F+++
Sbjct: 1 MSEVIDK---VLDLAKRRGIFWLSYEIYGGVAGFYDIGPVGVRIKNRIVELWRKYFVKDN 57
Query: 61 ---FFEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSA 117
EIE+P I P +VF ASGHVE F DPIVEC C +RADHLIE+ L VEG
Sbjct: 58 GDFVVEIESPMIGPAKVFEASGHVESFTDPIVECNNCKRIYRADHLIEDILKKSVEGLKP 117
Query: 118 EEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRL 177
EE+T+II+E+NI+C CGGELG+V FNL+F T IGPY Y+RPETAQG+F FKR+
Sbjct: 118 EELTRIIKENNIRCQYCGGELGEVRLFNLLFTTNIGPYTGNLGYIRPETAQGMFTAFKRV 177
Query: 178 NAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNP--NETEHPHFDEVK 235
R +LP G+ QIGK RNEISPRQG+IR+REFT E+E F +P N E+ K
Sbjct: 178 YEATRQRLPIGIAQIGKVGRNEISPRQGLIRMREFTIMEIEFFIDPEDNNIENIPLYRFK 237
Query: 236 HEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRF 295
KL + + KD E EE+V++ ++ + AY++ + + +GI E F
Sbjct: 238 DTKLNILTASEKEKDGKPQEFKLEESVREKIIIQPWMAYWMAVASSFVKALGINE--FYF 295
Query: 296 RQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDK 355
++LP ERAHYS T+D VE G AYR DYDLSRHMK SG DLT+ Y +
Sbjct: 296 EEKLPYERAHYSKQTFDQIAVINGIK-VEISGHAYRGDYDLSRHMKYSGQDLTIFRKYKE 354
Query: 356 PKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDGYELS 415
PK++K+ V +N + K K+ K+I E + S EE+ ++++ ++ID LS
Sbjct: 355 PKMIKKKTVIVNNTKL--KDKELRKKIMELLNGKSAEEIEQMIR-----NNVMIDDKPLS 407
Query: 416 KDDFI-IKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAP 474
+FI I E EEKV GE IPHV+EPSFG++R +L + ++ +++GR+ L + + +AP
Sbjct: 408 --EFINIVEREEKVHGEHFIPHVVEPSFGVERTLFLTILSAYK-EKEGRVLLSLPRHLAP 464
Query: 475 IEVAVLPLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDN 534
++AV PL+ +E L + + ++ R+ E + V+YD+ SIG+RY R DEIG P+ +T+D
Sbjct: 465 YDIAVFPLLEREELIRKSVEI-RESLSEKYEVLYDDSGSIGRRYARADEIGIPFAITVDP 523
Query: 535 QTPIDGTVTIRDRDTREQIRVKLEDVPRKLKELIFG 570
QT +D +VTIRDRD+ +Q+RVK++D+ L++L G
Sbjct: 524 QTLVDNSVTIRDRDSWKQVRVKIDDLKISLEKLFRG 559
>gb|AAG20454.1| (AE005117) glycine-tRNA synthetase; GlyS [Halobacterium sp. NRC-1]
Length = 576
Score = 444 bits (1130), Expect = e-123
Identities = 246/566 (43%), Positives = 341/566 (59%), Gaps = 15/566 (2%)
Query: 9 EYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI-REGFFEIETP 67
E + +L RRRGF + + E YGG+ GFY YGP GA +KR IE R+ F+ REG EI++P
Sbjct: 3 ETVSELARRRGFFFQASEAYGGAAGFYTYGPEGAALKRNIEDAWRDRFVTREGNMEIDSP 62
Query: 68 DITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGI-DVEGKSAEEMTKIIRE 126
+TPE VF ASGH++ F D +VEC CG RADH+IE+ + D E +E+ +I +
Sbjct: 63 TVTPEPVFQASGHLDDFDDMLVECPDCGESHRADHVIEDNTDVEDAESMPTDEVEALIAD 122
Query: 127 HNIKCPECGGELG--DVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFARNK 184
H + CP CGG L V FNLMF+T IGP YLRPETAQG+F F RL +ARN+
Sbjct: 123 HELVCPACGGPLAGQSVTGFNLMFDTTIGPGDGDPGYLRPETAQGMFTEFPRLKEYARNQ 182
Query: 185 LPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPI 244
LPFGV Q+G YRNEISPR ++R REFT AE+E F +P + P D V +L LYP+
Sbjct: 183 LPFGVAQVGTGYRNEISPRNALLRTREFTMAELEFFVDP-AGDGPALDRVADVELPLYPV 241
Query: 245 E-NQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEER 303
+ Q + LT +EA+ +G + + AY+L K+ +G+ D+ RFRQ LP E
Sbjct: 242 DAQQAAGEEYLRLTPQEALAEGVVGGEWVAYFLARSKQWFERVGVDMDRFRFRQHLPGEL 301
Query: 304 AHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVKRLK 363
AHY++D WDAE + WVE G+A RTDYDLS+H + + TV YD+PK V+R
Sbjct: 302 AHYASDCWDAEGEVDG-DWVELEGVASRTDYDLSKHDEHADDSFTVFQAYDEPKTVERAS 360
Query: 364 VSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDG--YELSKDDFII 421
V M +GP+ A + + + A++ R+ +E + +DG Y + +
Sbjct: 361 VDPEMSYLGPEFGGAAGDVADALAALA---ARDRAAFDGDEVTVDVDGEAYTVPTERTGF 417
Query: 422 KEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE-DG--RIYLKIKKDMAPIEVA 478
+ EE +G IIPHV+EP+FGI R Y L +S DE DG R L++ ++AP V
Sbjct: 418 EVAEETESGRHIIPHVVEPAFGIGRAVYTALAHSYEADEVDGEPRDVLRLPAEVAPTTVG 477
Query: 479 VLPLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPI 538
V PL+ K+ L + A ++ +L+ G V YD+ +IG+RY R DE+GTPYCVT+D +
Sbjct: 478 VFPLMDKDGLGERAREIAAELRAAGLAVTYDDSGNIGRRYRRQDEVGTPYCVTVDYEALE 537
Query: 539 DGTVTIRDRDTREQIRVKLEDVPRKL 564
+G VT+RDRDT Q+RV + +V L
Sbjct: 538 EGAVTLRDRDTTTQVRVPIAEVAETL 563
>gb|AAF49668.1| (AE003532) CG6778 gene product [Drosophila melanogaster]
Length = 765
Score = 407 bits (1034), Expect = e-112
Identities = 242/593 (40%), Positives = 342/593 (56%), Gaps = 32/593 (5%)
Query: 5 FDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAF-IREGFFE 63
FD+ + ++DL++RR F SF IYGG G YD+GP+G +K I R+ F + E E
Sbjct: 151 FDRAK-MEDLLKRRFFYDQSFAIYGGITGQYDFGPMGCALKSNILALWRQYFALEEQMLE 209
Query: 64 IETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLG-------------- 109
++ +TPE V ASGHVE+F D +V+ K G FR DHLI++ L
Sbjct: 210 VDCSILTPEPVLKASGHVERFADLMVKDVKTGECFRLDHLIKQALEKLSKAKDATPALQA 269
Query: 110 ------IDVEGKSAEEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLR 163
I ++G + +E+ ++ ++NIK P G +L + FNLMF T IGP K +LR
Sbjct: 270 ECEDIIIKLDGLNKQELAGVLAKYNIKSPLTGNDLTEPIEFNLMFATQIGPTGLVKGFLR 329
Query: 164 PETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNP 223
PETAQGIFVNFKRL F + KLPF V QIG ++RNEISPR G+IR+REFT AE+E F +P
Sbjct: 330 PETAQGIFVNFKRLLEFNQGKLPFAVAQIGNSFRNEISPRSGLIRVREFTMAEIEHFCDP 389
Query: 224 NETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKIL 283
+HP F +K EKL LY NQ+ ++ EAV + N YY+ I++ L
Sbjct: 390 VLKDHPKFGNIKSEKLTLYSACNQMDGKSAAQVQIGEAVASKLVANETLGYYMARIQQFL 449
Query: 284 LDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMS 343
L IGI + +RFRQ + E AHY+ D WDAE+ + +GWVECVG A R+ YDL +H +
Sbjct: 450 LAIGIKPECLRFRQHMSNEMAHYACDCWDAEILTS-YGWVECVGCADRSAYDLGQHTAAT 508
Query: 344 GADLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNE 403
G L PK V+ ++ N +++G KK+AK I + + +S EE+ ++ ++L
Sbjct: 509 GVRLVAEKRLPAPKTVEVSEIVPNKQALGKTFKKEAKNITDALAKLSLEEITKVEEQLAG 568
Query: 404 EGKIVI---DG--YELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTI 458
+G+ + DG ++L KD +K + V E+ IP V+EPSFGI R Y LLE+S
Sbjct: 569 DGQYKLTTADGQSHDLGKDTISVKHSTKTVHVEEFIPSVVEPSFGIGRIMYSLLEHSFQC 628
Query: 459 --DEDGRIYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQK-EGFIVVYDEKDSIG 515
++ R Y + +API+ ++LPL L L K E V D SIG
Sbjct: 629 RDGDEQRCYFTLPPLVAPIKCSILPLSNNTDFQPYTQKLSSALTKAELSHKVDDSSGSIG 688
Query: 516 KRYMRYDEIGTPYCVTIDNQTPID-GTVTIRDRDTREQIRVKLEDVPRKLKEL 567
+RY R DEI PY +T+D T + TVT+RDR+T +Q+RV LE+V +K+L
Sbjct: 689 RRYARTDEIAIPYGITVDFDTLKEPHTVTLRDRNTMKQVRVGLEEVVGVVKDL 741
>sp|Q10039|SYG_CAEEL PROBABLE GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|7507632|pir||T16843 hypothetical protein T10F2.1 -
Caenorhabditis elegans >gi|727447|gb|AAA64291.1|
(U23412) coded for by C. elegans cDNA yk46g2.5; coded
for by C. elegans cDNA yk46g2.3; similar to glycyl-tRNA
synthetase [Caenorhabditis elegans]
Length = 746
Score = 401 bits (1019), Expect = e-110
Identities = 240/598 (40%), Positives = 345/598 (57%), Gaps = 36/598 (6%)
Query: 5 FDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI-REGFFE 63
FD+ + L+DL++RR F SF IYGG G YD+GP+G ++K + ++ R+ FI EG E
Sbjct: 133 FDRLK-LEDLLKRRFFYDQSFAIYGGVTGLYDFGPMGCSLKANMLQEWRKHFILEEGMLE 191
Query: 64 IETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETL--------------- 108
++ +TPE V ASGHV++F D +V+ K G FRADHLI+ ++
Sbjct: 192 VDCTSLTPEPVLKASGHVDRFADWMVKDMKNGECFRADHLIKNSIEKLLNDKKTSAAVKQ 251
Query: 109 -GIDV----EGKSAEEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLR 163
G DV EG ++M ++I N K P G +L + FNLMF T IGP D KA+LR
Sbjct: 252 DGQDVLARLEGFDNKDMHEVITRFNFKSPITGNDLTEPIAFNLMFPTQIGPTGDFKAFLR 311
Query: 164 PETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNP 223
PETAQGIFVNFKRL F + KLPF QIG +RNEISPRQG+IR+REFT E+E F +P
Sbjct: 312 PETAQGIFVNFKRLLEFNQGKLPFAAAQIGLGFRNEISPRQGLIRVREFTMCEIEHFVDP 371
Query: 224 NETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKIL 283
+ F +V +KL L+ NQL E+ EAV K + N YY+ + L
Sbjct: 372 EDKSLAKFAKVADQKLVLFSACNQLDGAPAQEVAIGEAVAKKTVANETLGYYMARCHQFL 431
Query: 284 LDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMS 343
+ +GI ++RFRQ L E AHY+ D WDAE+ + +GW+ECVG A R YDL +H K +
Sbjct: 432 MKVGIDGRRLRFRQHLSNEMAHYAQDCWDAEILTS-YGWIECVGNADRACYDLQQHYKAT 490
Query: 344 GADLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKL-- 401
L +P V ++ NM +G KKDAK+I +Q ++ E++ L ++L
Sbjct: 491 NVKLVAEKKLPEPVDVNFVEAQANMALLGKSFKKDAKKIQTSLQQLTSEQVSALEEELLA 550
Query: 402 NEEGKIVIDG--YELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTID 459
+ + +DG Y L+ + IK+ +K+ ++I P V+EPS+GI R Y LLE+S
Sbjct: 551 KKLYNLSVDGQNYALTPEHLNIKKYTKKIHVQEITPSVIEPSYGIGRIMYALLEHSFRQR 610
Query: 460 E--DGRIYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQK-EGFIVVYDEKDSIGK 516
E + R +L K +API+ +VLP+ A + L + + +L + E V D +IG+
Sbjct: 611 EGDEQRTFLAFKPLVAPIKCSVLPISANDTLIPVMDAVKEELSRFEMSYKVDDSSGTIGR 670
Query: 517 RYMRYDEIGTPYCVTID----NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKELIFG 570
RY R DEIG P+ +T+D TP TVTIR +T QIR+++ ++ R + +L+ G
Sbjct: 671 RYARTDEIGIPFGITVDFDSLKTTPF--TVTIRHAETMSQIRLEVSELGRLISDLVAG 726
>gb|AAA86443.1| (U09510) glycyl-tRNA synthetase [Homo sapiens]
Length = 685
Score = 388 bits (986), Expect = e-107
Identities = 227/593 (38%), Positives = 335/593 (56%), Gaps = 35/593 (5%)
Query: 11 LQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREG-FFEIETPDI 69
++D ++RR F +F IYGG G YD+GP+G +K I + R+ FI+E EI+ +
Sbjct: 70 MEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTML 129
Query: 70 TPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLG-------IDVEGKSA----- 117
TPE V SGHV+KF D +V+ K G FRADHL++ L VE KS
Sbjct: 130 TPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVL 189
Query: 118 --------EEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQG 169
+E+ + +N+K P G +L FNLMF+T+IGP + YLRPETAQG
Sbjct: 190 AQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQG 249
Query: 170 IFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHP 229
IF+NFKRL F + KLPF QIG ++RNEISPR G+IR+REFT AE+E F +P+E +HP
Sbjct: 250 IFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHP 309
Query: 230 HFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIP 289
F V L LY + Q+ ++ +AV++G + NT Y++ I L +GI
Sbjct: 310 KFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGIS 369
Query: 290 EDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTV 349
DK+RFRQ + E AHY+ D WDAE + +GW+E VG A R+ YDLS H + + L
Sbjct: 370 PDKLRFRQHMENEMAHYACDCWDAESKTS-YGWIEIVGCADRSCYDLSCHARATKVPLVA 428
Query: 350 MIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVI 409
+PK V ++ + ++G KKDAK + E + E + E+ LNE+G+ I
Sbjct: 429 EKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEIEMLLNEKGEFTI 488
Query: 410 D----GYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE--DGR 463
+ ++L+KD +K ++ + E+++P+V+EPSFG+ R Y + E++ + E + R
Sbjct: 489 ETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQR 548
Query: 464 IYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQKEGFI-VVYDEKDSIGKRYMRYD 522
+ +AP + +VLPL + +L L + G V D SIG+RY R D
Sbjct: 549 TFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTD 608
Query: 523 EIGTPYCVTID----NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKELIFGS 571
EIG + VTID N+TP T T+RDRD+ QIR ++ ++P +++L G+
Sbjct: 609 EIGVAFGVTIDFDTVNKTP--HTATLRDRDSMRQIRAEISELPSIVQDLANGN 659
>gi|6996010 glycyl-tRNA synthetase; GlyRS; glycine tRNA ligase [Homo sapiens]
>gi|730868|sp|P41250|SYG_HUMAN GLYCYL-TRNA SYNTHETASE
(GLYCINE--TRNA LIGASE) (GLYRS) >gi|600727|gb|AAA57001.1|
(U09587) glycyl-tRNA synthetase [Homo sapiens]
Length = 685
Score = 388 bits (986), Expect = e-107
Identities = 227/593 (38%), Positives = 335/593 (56%), Gaps = 35/593 (5%)
Query: 11 LQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREG-FFEIETPDI 69
++D ++RR F +F IYGG G YD+GP+G +K I + R+ FI+E EI+ +
Sbjct: 70 MEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTML 129
Query: 70 TPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLG-------IDVEGKSA----- 117
TPE V SGHV+KF D +V+ K G FRADHL++ L VE KS
Sbjct: 130 TPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVL 189
Query: 118 --------EEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQG 169
+E+ + +N+K P G +L FNLMF+T+IGP + YLRPETAQG
Sbjct: 190 AQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQG 249
Query: 170 IFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHP 229
IF+NFKRL F + KLPF QIG ++RNEISPR G+IR+REFT AE+E F +P+E +HP
Sbjct: 250 IFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHP 309
Query: 230 HFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIP 289
F V L LY + Q+ ++ +AV++G + NT Y++ I L +GI
Sbjct: 310 KFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGIS 369
Query: 290 EDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTV 349
DK+RFRQ + E AHY+ D WDAE + +GW+E VG A R+ YDLS H + + L
Sbjct: 370 PDKLRFRQHMENEMAHYACDCWDAESKTS-YGWIEIVGCADRSCYDLSCHARATKVPLVA 428
Query: 350 MIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVI 409
+PK V ++ + ++G KKDAK + E + E + E+ LNE+G+ I
Sbjct: 429 EKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTI 488
Query: 410 D----GYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE--DGR 463
+ ++L+KD +K ++ + E+++P+V+EPSFG+ R Y + E++ + E + R
Sbjct: 489 ETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQR 548
Query: 464 IYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQKEGFI-VVYDEKDSIGKRYMRYD 522
+ +AP + +VLPL + +L L + G V D SIG+RY R D
Sbjct: 549 TFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTD 608
Query: 523 EIGTPYCVTID----NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKELIFGS 571
EIG + VTID N+TP T T+RDRD+ QIR ++ ++P +++L G+
Sbjct: 609 EIGVAFGVTIDFDTVNKTP--HTATLRDRDSMRQIRAEISELPSIVQDLANGN 659
>pir||A55314 glycine--tRNA ligase (EC 6.1.1.14) precursor [validated] - human
>gi|1311463|dbj|BAA06338.1| (D30658) glycyl tRNA
synthetase [Homo sapiens]
Length = 739
Score = 388 bits (986), Expect = e-107
Identities = 227/593 (38%), Positives = 335/593 (56%), Gaps = 35/593 (5%)
Query: 11 LQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREG-FFEIETPDI 69
++D ++RR F +F IYGG G YD+GP+G +K I + R+ FI+E EI+ +
Sbjct: 124 MEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTML 183
Query: 70 TPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLG-------IDVEGKSA----- 117
TPE V SGHV+KF D +V+ K G FRADHL++ L VE KS
Sbjct: 184 TPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVL 243
Query: 118 --------EEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQG 169
+E+ + +N+K P G +L FNLMF+T+IGP + YLRPETAQG
Sbjct: 244 AQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQG 303
Query: 170 IFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHP 229
IF+NFKRL F + KLPF QIG ++RNEISPR G+IR+REFT AE+E F +P+E +HP
Sbjct: 304 IFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHP 363
Query: 230 HFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIP 289
F V L LY + Q+ ++ +AV++G + NT Y++ I L +GI
Sbjct: 364 KFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGIS 423
Query: 290 EDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTV 349
DK+RFRQ + E AHY+ D WDAE + +GW+E VG A R+ YDLS H + + L
Sbjct: 424 PDKLRFRQHMENEMAHYACDCWDAESKTS-YGWIEIVGCADRSCYDLSCHARATKVPLVA 482
Query: 350 MIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVI 409
+PK V ++ + ++G KKDAK + E + E + E+ LNE+G+ I
Sbjct: 483 EKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTI 542
Query: 410 D----GYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE--DGR 463
+ ++L+KD +K ++ + E+++P+V+EPSFG+ R Y + E++ + E + R
Sbjct: 543 ETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQR 602
Query: 464 IYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQKEGFI-VVYDEKDSIGKRYMRYD 522
+ +AP + +VLPL + +L L + G V D SIG+RY R D
Sbjct: 603 TFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTD 662
Query: 523 EIGTPYCVTID----NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKELIFGS 571
EIG + VTID N+TP T T+RDRD+ QIR ++ ++P +++L G+
Sbjct: 663 EIGVAFGVTIDFDTVNKTP--HTATLRDRDSMRQIRAEISELPSIVQDLANGN 713
>gi|11420984 glycyl-tRNA synthetase [Homo sapiens]
Length = 739
Score = 388 bits (986), Expect = e-107
Identities = 227/593 (38%), Positives = 335/593 (56%), Gaps = 35/593 (5%)
Query: 11 LQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREG-FFEIETPDI 69
++D ++RR F +F IYGG G YD+GP+G +K I + R+ FI+E EI+ +
Sbjct: 124 MEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTML 183
Query: 70 TPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLG-------IDVEGKSA----- 117
TPE V SGHV+KF D +V+ K G FRADHL++ L VE KS
Sbjct: 184 TPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVL 243
Query: 118 --------EEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQG 169
+E+ + +N+K P G +L FNLMF+T+IGP + YLRPETAQG
Sbjct: 244 AQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQG 303
Query: 170 IFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHP 229
IF+NFKRL F + KLPF QIG ++RNEISPR G+IR+REFT AE+E F +P+E +HP
Sbjct: 304 IFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHP 363
Query: 230 HFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIP 289
F V L LY + Q+ ++ +AV++G + NT Y++ I L +GI
Sbjct: 364 KFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGIS 423
Query: 290 EDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTV 349
DK+RFRQ + E AHY+ D WDAE + +GW+E VG A R+ YDLS H + + L
Sbjct: 424 PDKLRFRQHMENEMAHYACDCWDAESKTS-YGWIEIVGCADRSCYDLSCHARATKVPLVA 482
Query: 350 MIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVI 409
+PK V ++ + ++G KKDAK + E + E + E+ LNE+G+ I
Sbjct: 483 EKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTI 542
Query: 410 D----GYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE--DGR 463
+ ++L+KD +K ++ + E+++P+V+EPSFG+ R Y + E++ + E + R
Sbjct: 543 ETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQR 602
Query: 464 IYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQKEGFI-VVYDEKDSIGKRYMRYD 522
+ +AP + +VLPL + +L L + G V D SIG+RY R D
Sbjct: 603 TFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTD 662
Query: 523 EIGTPYCVTID----NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKELIFGS 571
EIG + VTID N+TP T T+RDRD+ QIR ++ ++P +++L G+
Sbjct: 663 EIGVAFGVTIDFDTVNKTP--HTATLRDRDSMRQIRAEISELPSIVQDLANGN 713
>sp|Q04451|SYG_BOMMO GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|665680|gb|AAA62231.1| (L08106) glycyl-tRNA
synthetase [Bombyx mori]
Length = 680
Score = 386 bits (982), Expect = e-106
Identities = 224/592 (37%), Positives = 337/592 (56%), Gaps = 33/592 (5%)
Query: 5 FDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI-REGFFE 63
FD+ + ++DL++RR F SF IYGG G +D+GP+G +K + ++ FI +E E
Sbjct: 65 FDRAK-MEDLIKRRFFYDQSFAIYGGITGQFDFGPMGCALKSNMIHLWKKFFILQEQMLE 123
Query: 64 IETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIE------------------ 105
+E +TPE V ASGHVE+F D + + K G FR DHLI+
Sbjct: 124 VECSILTPEPVLKASGHVERFADLMTKDIKTGECFRLDHLIKGHLEKIKSDKNTKIELKA 183
Query: 106 --ETLGIDVEGKSAEEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLR 163
E + I ++G +A+EM+ +++ +K P G +L FNLMF T IGP K +LR
Sbjct: 184 EIEDILIKLDGMNADEMSALMKRFEMKSPISGNDLTPPIEFNLMFNTQIGPSGLVKGFLR 243
Query: 164 PETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNP 223
PETAQGIFVNFKRL F + +LPF QIG ++RNEISPR G++R+REFT E+E F +
Sbjct: 244 PETAQGIFVNFKRLLEFNQGRLPFAAAQIGNSFRNEISPRSGLLRVREFTMCEIEHFCDV 303
Query: 224 NETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKIL 283
EHP F+ VK+ + LY +NQ + T +AV KG + N Y++ I +
Sbjct: 304 K--EHPKFESVKNTQSLLYSADNQEQGKPADLTTIGDAVCKGIVNNETLGYFMARIHMYM 361
Query: 284 LDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMS 343
L +GI ++RFRQ + E AHY+ D WDAE S +GW+ECVG A R+ YDL++H K +
Sbjct: 362 LAVGIDPKRLRFRQHMGNEMAHYACDCWDAECLSS-YGWIECVGCADRSAYDLTQHTKAT 420
Query: 344 GADLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNE 403
G L PK ++ ++ N +G KKD++ IN+ + + L E+ K+L+
Sbjct: 421 GIRLAAEKKLPAPKQIEVVEAIANNGRIGKAFKKDSQAINDTLATLDNAALEEMQKELDS 480
Query: 404 EGKIVI----DGYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTID 459
G+ + ++L+ +K+ ++ + E+IIP V+EPSFG+ R Y +LE++ +
Sbjct: 481 NGEYTLITARGEFKLTPSLVNVKKTQKTIHVEEIIPSVIEPSFGVGRILYCILEHNFRMR 540
Query: 460 E--DGRIYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKL-QKEGFIVVYDEKDSIGK 516
E + R Y + +AP++ VLPL DL ++L + V D SIG+
Sbjct: 541 EGDEQRTYFSLPPTVAPMKCVVLPLSGNAEFQPFVRDLSQELITVDVSHKVDDSSGSIGR 600
Query: 517 RYMRYDEIGTPYCVTIDNQTPID-GTVTIRDRDTREQIRVKLEDVPRKLKEL 567
RY R DE+G PY VT+D T + TVT+R+RD+ Q+R+ + DVP +++L
Sbjct: 601 RYARTDELGVPYAVTVDFDTIKEPHTVTLRERDSMRQVRLPMADVPTVVRDL 652
>sp|Q10179|SYG_SCHPO PUTATIVE GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|7490605|pir||T38704 glycyl tRNA synthetase - fission
yeast (Schizosaccharomyces pombe)
>gi|1182050|emb|CAA93301.1| (Z69369) glycyl tRNA
synthetase [Schizosaccharomyces pombe]
Length = 652
Score = 384 bits (977), Expect = e-105
Identities = 233/627 (37%), Positives = 346/627 (55%), Gaps = 64/627 (10%)
Query: 5 FDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAF-IREGFFE 63
FD+ ++ ++LM++R F SF+IYGG G YDYGP G+ ++ + R+ F I E E
Sbjct: 10 FDRTQF-EELMKKRFFFSPSFQIYGGISGLYDYGPPGSALQSNLVDIWRKHFVIEESMLE 68
Query: 64 IETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEG--------- 114
++ +TP +V SGHV+KF D + + G FRADHL+EE L ++G
Sbjct: 69 VDCSMLTPHEVLKTSGHVDKFADWMCKDPATGEIFRADHLVEEVLEARLKGDKEARGQNS 128
Query: 115 ---------------------------KSAEE---------------MTKIIREHNIKCP 132
K+ EE + +++++++I+ P
Sbjct: 129 NDQPEESDDKKKRKKKVKEIRATRLDDKTVEEYEFILAQIDNYDGDQLGELMKKYDIRNP 188
Query: 133 ECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFARNKLPFGVFQI 192
GEL FNLMFET IGP K YLRPETAQG F+NF RL F K+PF +
Sbjct: 189 ATNGELETPRQFNLMFETQIGPSGGLKGYLRPETAQGQFLNFSRLLEFNNGKVPFASAMV 248
Query: 193 GKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPIENQLK-DL 251
GKA+RNEISPR G++R+REF AEVE F +P EH FDEV H LRL P QL+
Sbjct: 249 GKAFRNEISPRSGLLRVREFLMAEVEHFVDPKNKEHDRFDEVSHMPLRLLPRGVQLEGKT 308
Query: 252 GMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEERAHYSADTW 311
++E+ +AVKKG + NT Y++ I L IGI +++RFRQ + E AHY+ D W
Sbjct: 309 DILEMPIGDAVKKGIVDNTTLGYFMARISLFLEKIGIDMNRVRFRQHMSNEMAHYACDCW 368
Query: 312 DAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVKRLKVSLNMKSV 371
DAE+ +GW+ECVG A R+ YDLS H K + L V +P +V++ +V +N K
Sbjct: 369 DAEIQCS-YGWIECVGCADRSAYDLSVHSKATKTPLVVQEALPEPVVVEQFEVEVNRKKF 427
Query: 372 GPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIV--IDGYELSKDDFIIKEVEEKVT 429
GP+ K+DAK + E + + E E E +L EGKI+ ++G E + + ++ +E++
Sbjct: 428 GPRFKRDAKAVEEAMISWPESEKVEKSAQLVAEGKIIVNVNGVEHTVESDLV-TIEKRKH 486
Query: 430 GEKI---IPHVLEPSFGIDRPFYLLLENSL-TIDED-GRIYLKIKKDMAPIEVAVLPLVA 484
E I P+V+EPSFG+ R Y+L+E++ T ED R L +API+ ++PL
Sbjct: 487 TEHIRTYTPNVIEPSFGLGRILYVLMEHAYWTRPEDVNRGVLSFPASIAPIKALIVPLSR 546
Query: 485 KEPLTKIAYDLFRKLQKEGFIVVYDEKD-SIGKRYMRYDEIGTPYCVTIDNQTPIDGTVT 543
L KL+ G D+ + +IG+RY R DE+GTP+ +T+D +T + T+T
Sbjct: 547 NAEFAPFVKKLSAKLRNLGISNKIDDSNANIGRRYARNDELGTPFGLTVDFETLQNETIT 606
Query: 544 IRDRDTREQIRVKLEDVPRKLKELIFG 570
+R+RD+ +Q+R ++V L ++ G
Sbjct: 607 LRERDSTKQVRGSQDEVIAALVSMVEG 633
>sp|O23627|SYG_ARATH GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|2564215|emb|CAA05162.1| (AJ002062) glycyl-tRNA
synthetase [Arabidopsis thaliana]
>gi|9972358|gb|AAG10608.1|AC008030_8 (AC008030)
glycyl-tRNA synthetase [Arabidopsis thaliana]
Length = 729
Score = 380 bits (966), Expect = e-104
Identities = 225/580 (38%), Positives = 328/580 (55%), Gaps = 41/580 (7%)
Query: 15 MRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI-REGFFEIETPDITPEQ 73
+ RR F SF+IY G G +DYGP G IK + R+ FI E E++ P +TPE
Sbjct: 124 LERRLFYIPSFKIYSGVAGLFDYGPPGCAIKSNVLSFWRQHFILEENMLEVDCPCVTPEV 183
Query: 74 VFIASGHVEKFVDPIVECKKCGARFRADHLIEE----------TLGID-----------V 112
V ASGHV+KF D +V+ +K G +RADHL+++ T+ + +
Sbjct: 184 VLKASGHVDKFTDLMVKDEKTGTCYRADHLLKDYCTEKLEKDLTISAEKAAELKDVLAVM 243
Query: 113 EGKSAEEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFV 172
E S E++ IRE+ I P+ L D + FNLMF+T IGP Y+RPETAQGIFV
Sbjct: 244 EDFSPEQLGAKIREYGITAPDTKNPLSDPYPFNLMFQTSIGPSGLIPGYMRPETAQGIFV 303
Query: 173 NFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFD 232
NFK L + KLPF QIG+A+RNEISPRQG++R+REFT AE+E F +P HP F
Sbjct: 304 NFKDLYYYNGKKLPFAAAQIGQAFRNEISPRQGLLRVREFTLAEIEHFVDPENKSHPKFS 363
Query: 233 EVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDK 292
+V + ++P E Q+ +L EAV KG + N Y++ + L +GI +++
Sbjct: 364 DVAKLEFLMFPREEQMSGQSAKKLCLGEAVAKGTVNNETLGYFIGRVYLFLTRLGIDKER 423
Query: 293 IRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIH 352
+RFRQ L E AHY+AD WDAE+ S +GW+ECVG+A R+ YDL H SG L
Sbjct: 424 LRFRQHLANEMAHYAADCWDAEIESS-YGWIECVGIADRSAYDLRAHSDKSGTPLVAEEK 482
Query: 353 YDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGKIVIDGY 412
+ +PK V++L ++ K +G K + K + E ++AM+EEE E+ L +G++
Sbjct: 483 FAEPKEVEKLVITPVKKELGLAFKGNQKNVVESLEAMNEEEAMEMKATLESKGEVEFYVC 542
Query: 413 ELSKDDFIIKEV-----EEKVTGEKII-PHVLEPSFGIDRPFYLLLENSLTI------DE 460
L K I K + E+K +++ P V+EPSFGI R Y L E+ + DE
Sbjct: 543 TLKKSVNIKKNMVSISKEKKKEHQRVFTPSVIEPSFGIGRIIYCLYEHCFSTRPSKAGDE 602
Query: 461 DGRIYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQKEGFIVVYD-EKDSIGKRYM 519
++ + +API+ V PLV + ++A + ++L G D SIGKRY
Sbjct: 603 QLNLF-RFPPLVAPIKCTVFPLVQNQQFEEVAKVISKELASVGISHKIDITGTSIGKRYA 661
Query: 520 RYDEIGTPYCVTIDNQTPIDGTVTIRDRDTREQIRVKLED 559
R DE+G P+ +T+D+ T +VTIR+RD+++Q+RV L++
Sbjct: 662 RTDELGVPFAITVDSDT----SVTIRERDSKDQVRVTLKE 697
>pir||A46636 glycine--tRNA ligase (EC 6.1.1.14) - silkworm
Length = 687
Score = 376 bits (954), Expect = e-103
Identities = 224/599 (37%), Positives = 337/599 (55%), Gaps = 40/599 (6%)
Query: 5 FDKYEYLQDLMRRRGFAWGSFE------IYGGSRGFYDYGPLGATIKRKIEKKIREAFI- 57
FD+ + ++DL++RR F SF IYGG G +D+GP+G +K + ++ FI
Sbjct: 65 FDRAK-MEDLIKRRFFYDQSFSMTSRFAIYGGITGQFDFGPMGCALKSNMIHLWKKFFIL 123
Query: 58 REGFFEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIE------------ 105
+E E+E +TPE V ASGHVE+F D + + K G FR DHLI+
Sbjct: 124 QEQMLEVECSILTPEPVLKASGHVERFADLMTKDIKTGECFRLDHLIKGHLEKIKSDKNT 183
Query: 106 --------ETLGIDVEGKSAEEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKD 157
E + I ++G +A+EM+ +++ +K P G +L FNLMF T IGP
Sbjct: 184 KIELKAEIEDILIKLDGMNADEMSALMKRFEMKSPISGNDLTPPIEFNLMFNTQIGPSGL 243
Query: 158 KKAYLRPETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRN-EISPRQGMIRLREFTQAE 216
K +LRPETAQGIFVNFKRL F + +LPF QIG ++RN EISPR G++R+REFT E
Sbjct: 244 VKGFLRPETAQGIFVNFKRLLEFNQGRLPFAAAQIGNSFRNPEISPRSGLLRVREFTMCE 303
Query: 217 VEIFFNPNETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYL 276
+E F + EHP F+ VK+ + LY +NQ + T +AV KG + N Y++
Sbjct: 304 IEHFCDVK--EHPKFESVKNTQSLLYSADNQEQGKPADLTTIGDAVCKGIVNNETLGYFM 361
Query: 277 VMIKKILLDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDL 336
I +L +GI ++RFRQ + E AHY+ D WDAE S +GW+ECVG A R+ YDL
Sbjct: 362 ARIHMYMLAVGIDPKRLRFRQHMGNEMAHYACDCWDAECLSS-YGWIECVGCADRSAYDL 420
Query: 337 SRHMKMSGADLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRE 396
++H K +G L PK ++ ++ N +G KKD++ IN+ + + L E
Sbjct: 421 TQHTKATGIRLAAEKKLPAPKQIEVVEAIANNGPIGKAFKKDSQAINDTLATLDNAALEE 480
Query: 397 LVKKLNEEGKIVI----DGYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLL 452
+ K+L+ G+ + ++L+ +K+ ++ + E+IIP V+EPSFG+ R Y +L
Sbjct: 481 MQKELDSNGEYTLITARGEFKLTPSLVNVKKTQKTIHVEEIIPSVIEPSFGVGRILYCIL 540
Query: 453 ENSLTIDE--DGRIYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKL-QKEGFIVVYD 509
E++ + E + R Y + +AP++ VLPL DL ++L + V D
Sbjct: 541 EHNFRMREGDEQRTYFSLPPTVAPMKCVVLPLSGNAEFQPFVRDLSQELITVDVSHKVDD 600
Query: 510 EKDSIGKRYMRYDEIGTPYCVTIDNQTPID-GTVTIRDRDTREQIRVKLEDVPRKLKEL 567
SIG+RY R DE+G PY VT+D T + TVT+R+RD+ Q+R+ + DVP +++L
Sbjct: 601 SSGSIGRRYARTDELGVPYAVTVDFDTIKEPHTVTLRERDSMRQVRLPMADVPTVVRDL 659
>gi|6325338 Ypr081cp [Saccharomyces cerevisiae] >gi|2132408|pir||S69067
probable glycine--tRNA ligase (EC 6.1.1.14) - yeast
(Saccharomyces cerevisiae) >gi|1230687|gb|AAB68130.1|
(U51033) Highly similar to Glycyl-tRNA synthetase (Swiss
Prot. accession numbers P41250 and P38088)
[Saccharomyces cerevisiae]
Length = 618
Score = 372 bits (946), Expect = e-102
Identities = 220/591 (37%), Positives = 331/591 (55%), Gaps = 37/591 (6%)
Query: 11 LQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI-REGFFEIETPDI 69
L+ +RRR F SFEIYGG G +D GP G ++ + + RE FI E +++ P +
Sbjct: 12 LESTLRRRFFYTPSFEIYGGVSGLFDLGPPGCQLQNNLIRLWREHFIMEENMLQVDGPML 71
Query: 70 TPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLG-------------------- 109
TP V SGHV+KF D + K G +RADHLIE+TL
Sbjct: 72 TPYDVLKTSGHVDKFTDWMCRNPKTGEYYRADHLIEQTLKKRLLDKDVNPQDMKNMEKIL 131
Query: 110 IDVEGKSAEEMTKIIREHNIKCPECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQG 169
++G S E+ +++E+NI P L + FNLMFET IG KA+LRPETAQG
Sbjct: 132 TTIDGFSGPELNLVMQEYNINDPVTNDVLDALTSFNLMFETKIGASGQLKAFLRPETAQG 191
Query: 170 IFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHP 229
F+NF +L + K+PF IGK++RNEISPR G++R+REF AE+E F +P H
Sbjct: 192 QFLNFNKLLEINQGKIPFASASIGKSFRNEISPRSGLLRVREFLMAEIEHFVDPLNKSHA 251
Query: 230 HFDEVKHEKLRLYPIENQLKDLGMIEL----TAEEAVKKGYLMNTFFAYYLVMIKKILLD 285
F+EV +E++ L + +L++ G ++L T EAV G + N Y++ + + LL+
Sbjct: 252 KFNEVLNEEIPL--LSRRLQESGEVQLPVKMTIGEAVNSGMVENETLGYFMARVHQFLLN 309
Query: 286 IGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGA 345
IGI +DK RFRQ L E AHY+ D WD E+ + +GW+ECVG A R +DL+ H K +G
Sbjct: 310 IGINKDKFRFRQHLKNEMAHYATDCWDGEILTS-YGWIECVGCADRAAFDLTVHSKKTGR 368
Query: 346 DLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKLNEEG 405
LTV D PK V +N K G K K+ AK I + S++EL ++L + G
Sbjct: 369 SLTVKQKLDTPKERTEWVVEVNKKFFGSKFKQKAKLIESVLSKFSQDELIRRHEELEKNG 428
Query: 406 KIV--IDGYELSKDDFIIKEVEEKVTGEKI---IPHVLEPSFGIDRPFYLLLEN--SLTI 458
+ ++G ++ K D + ++ K T + I IP+V+EPSFG+ R Y + ++ + +
Sbjct: 429 EFTCQVNG-QIVKLDSSLVTIKMKTTLQHIREYIPNVIEPSFGLGRIIYCIFDHCFQVRV 487
Query: 459 DEDGRIYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQK-EGFIVVYDEKDSIGKR 517
D + R + +API+V V + + I + + L+K E + + D SIGK+
Sbjct: 488 DSESRGFFSFPLQIAPIKVFVTTISNNDGFPAILKRISQALRKREIYFKIDDSNTSIGKK 547
Query: 518 YMRYDEIGTPYCVTIDNQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKELI 568
Y R DE+GTP+ +TID +T D TVT+R+R++ Q+R + DV + +++
Sbjct: 548 YARNDELGTPFGITIDFETIKDQTVTLRERNSMRQVRGTITDVISTIDKML 598
>gi|6319597 Glycyl-tRNA synthase; Grs1p [Saccharomyces cerevisiae]
>gi|586057|sp|P38088|SYG_YEAST GLYCYL-TRNA SYNTHETASE
(GLYCINE--TRNA LIGASE) (GLYRS) >gi|1078212|pir||S48285
probable glycine--tRNA ligase (EC 6.1.1.14) GRS1 - yeast
(Saccharomyces cerevisiae) >gi|536402|emb|CAA85078.1|
(Z35990) ORF YBR121c [Saccharomyces cerevisiae]
>gi|565058|emb|CAA55623.1| (X78993) probable transfer
RNA-Gly synthetase [Saccharomyces cerevisiae]
Length = 667
Score = 363 bits (923), Expect = 2e-99
Identities = 222/628 (35%), Positives = 335/628 (52%), Gaps = 71/628 (11%)
Query: 9 EYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI-REGFFEIETP 67
E L+ ++R R F +F++YGG G YDYGP G + I R+ FI E E++
Sbjct: 18 EQLESVLRGRFFYAPAFDLYGGVSGLYDYGPPGCAFQNNIIDAWRKHFILEEDMLEVDCT 77
Query: 68 DITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIE---------------------- 105
+TP +V SGHV+KF D + K G FRADHL+E
Sbjct: 78 MLTPYEVLKTSGHVDKFSDWMCRDLKTGEIFRADHLVEEVLEARLKGDQEARGLVEDANA 137
Query: 106 -------------------------------ETLGIDVEGKSAEEMTKIIREHNIKCPEC 134
E + ++G S E+ +++ +++I P
Sbjct: 138 AAKDDAEKKKRKKKVKQIKAVKLDDDVVKEYEEILAKIDGYSGPELGELMEKYDIGNPVT 197
Query: 135 GGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFARNKLPFGVFQIGK 194
G L FNLMFET IGP K YLRPETAQG F+NF +L F +K PF IGK
Sbjct: 198 GETLESPRAFNLMFETAIGPSGQLKGYLRPETAQGQFLNFNKLLEFNNSKTPFASASIGK 257
Query: 195 AYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPIENQLKDLGMI 254
++RNEISPR G++R+REF AE+E F +P + HP F+E+K KL P +++ G
Sbjct: 258 SFRNEISPRAGLLRVREFLMAEIEHFVDPLDKSHPKFNEIKDIKLSFLP--RDVQEAGST 315
Query: 255 E---LTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEERAHYSADTW 311
E T EAV + N Y++ I + L+ IG+ E K+RFRQ + E AHY+AD W
Sbjct: 316 EPIVKTVGEAVASRMVDNETLGYFIARIYQFLMKIGVDESKLRFRQHMANEMAHYAADCW 375
Query: 312 DAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVKRLKVSLNMKSV 371
D E+ + +GW+ECVG A R+ YDL+ H K + L V D P V + ++ L K
Sbjct: 376 DGELKTS-YGWIECVGCADRSAYDLTVHSKKTKEKLVVRQKLDNPIEVTKWEIDLTKKLF 434
Query: 372 GPKLKKDAKRINEKIQAMSEEELRELVKKLNEEGK--IVIDGY--ELSKDDFIIKEVEEK 427
GPK +KDA ++ + MS+++L + L GK I +DG E+ DD ++K +E++
Sbjct: 435 GPKFRKDAPKVESHLLNMSQDDLASKAELLKANGKFTIKVDGVDGEVELDDKLVK-IEQR 493
Query: 428 VTGEKI---IPHVLEPSFGIDRPFYLLLENSL--TIDEDGRIYLKIKKDMAPIEVAVLPL 482
E + +P V+EPSFGI R Y + E+S +++ R L +AP +V ++PL
Sbjct: 494 TKVEHVREYVPSVIEPSFGIGRIIYSVFEHSFWNRPEDNARSVLSFPPLVAPTKVLLVPL 553
Query: 483 VAKEPLTKIAYDLFRKLQKEGFIVVYDEKD-SIGKRYMRYDEIGTPYCVTIDNQTPIDGT 541
+ L + +++ + L+K D+ SIGKRY R DE+GTP+ VTID ++ D +
Sbjct: 554 SNHKDLVPVHHEVAKILRKSQIPFKIDDSGVSIGKRYARNDELGTPFGVTIDFESAKDHS 613
Query: 542 VTIRDRDTREQIRVKLEDVPRKLKELIF 569
VT+R+RD+ +Q+R +E+V + ++++ +
Sbjct: 614 VTLRERDSTKQVRGSVENVIKAIRDITY 641
>gb|AAG38542.1|AF309805_7 (AF309805) glycyl tRNA synthetase [Pneumocystis carinii f. sp.
carinii]
Length = 615
Score = 329 bits (835), Expect = 5e-89
Identities = 209/609 (34%), Positives = 317/609 (51%), Gaps = 88/609 (14%)
Query: 11 LQDLMRRRGFAWGSFEIYGGSRGFYD--YGPLGATIKRKIEKKIREAFI-REGFFEIETP 67
L++L+++R F S+EIYGG F+ YGP G +++ I R+ F+ E EI T
Sbjct: 15 LEELLKKRFFYCPSYEIYGGIGSFWFVYYGPPGMALEQNILNVWRKHFVYEENMLEIGTS 74
Query: 68 DITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETL----------GID------ 111
+TP +V SGHV KF D + + G FRADH+I+E L G++
Sbjct: 75 IVTPHEVLETSGHVSKFRDWMCKDPSTGEVFRADHIIKEILLSRIKKRVESGLEGEKVEG 134
Query: 112 --------------------------VEGKSAEEMTKIIREHNIKCPECGGELGDVFYFN 145
++G E ++++I E++I+ P + FN
Sbjct: 135 GASGTKFDTLDESLSRIREYEDIISRIDGYDGEGLSRVIEEYDIRNPATNVRMEGPVGFN 194
Query: 146 LMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQG 205
LMF T IGP + YLRPETAQG F+NF +L F K+PF +GK++RNEISPR G
Sbjct: 195 LMFATEIGPKGNMTGYLRPETAQGQFLNFNKLLEFNNGKMPFASVVVGKSFRNEISPRSG 254
Query: 206 MIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPIENQLKDL-GMIELTAEEAVKK 264
++R+REFT AE+E + +P +H F+EV++ K++ E Q+ +IE+ EAV +
Sbjct: 255 LLRMREFTMAEIEHYVDPLNKDHRRFNEVENVKMKFLTREIQMSGKEEVIEMKIGEAVAR 314
Query: 265 GYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVE 324
G L NT AY+L I L+ IG+ ++K+RFRQ + E AHY++ WDAE+ + +GW+E
Sbjct: 315 GILENTTLAYFLARIHLFLIRIGMNQEKLRFRQHMNNEMAHYASVCWDAELLTS-YGWIE 373
Query: 325 CVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINE 384
CVG A R YDL+ H + + L V KP V V+++ K
Sbjct: 374 CVGCADRAAYDLTVHSEKTKEKLVVRELLPKPMEVTEWVVNVDKKK-------------- 419
Query: 385 KIQAMSEEELRELVKKLNEEGKIVIDGYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGI 444
I+ + F I++V++ ++ + IP+V+EPSFGI
Sbjct: 420 ------------------------IENLKFPSSLFTIEQVKKTISVREYIPNVIEPSFGI 455
Query: 445 DRPFYLLLENSLTI--DEDGRIYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQKE 502
R Y L+E+S I D+ R L +AP++ ++PL I L +L++
Sbjct: 456 GRILYSLIEHSYWIRSDDVDRCVLSFPPIVAPVKCLLVPLSNNSAFDPIIDKLSFELRQL 515
Query: 503 GFI-VVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDGTVTIRDRDTREQIRVKLEDVP 561
G V D +IG+RY R DE+GTP+ +T+D QT DG++T+R+RDT QIR +++
Sbjct: 516 GISHKVDDSSAAIGRRYSRNDELGTPFGITVDFQTVNDGSLTLRERDTTRQIRASEKEIL 575
Query: 562 RKLKELIFG 570
R +KEL G
Sbjct: 576 RVIKELSEG 584
>emb|CAC11352.1| (AL445063) glycyl-tRNA synthetase related [Thermoplasma
acidophilum]
Length = 476
Score = 284 bits (719), Expect = 2e-75
Identities = 154/349 (44%), Positives = 218/349 (62%), Gaps = 19/349 (5%)
Query: 13 DLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREGFFEIETPDITPE 72
+L +RRGF W S+ IYGGS GFYDYGPLG +K I + + REG ++TP I+P
Sbjct: 8 ELAKRRGFFWPSYMIYGGSSGFYDYGPLGTLLKDNIIAAWKREYAREGAIFLDTPVISPA 67
Query: 73 QVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEMTKIIREHNIKCP 132
VF ASGH+EKF D V+C KCG ++ + LI ++LGI+ K+ +E I+ ++++KCP
Sbjct: 68 DVFRASGHLEKFSDIAVKCSKCGTPYKFESLI-KSLGINEIAKTVDEAAAILEKYDVKCP 126
Query: 133 ECGGELGDVFYFNLMFETYIGPYKDKKAYLRPETAQGIFVNFKRLNAFARNKLPFGVFQI 192
+CG +L + + FNLMF YLRPETAQGIF+NFK L +ARN +P V Q+
Sbjct: 127 KCGEKLKNPYDFNLMFRV-----GSNDLYLRPETAQGIFINFKNLYNYARNSMPIIVCQV 181
Query: 193 GKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPIENQLKDLG 252
GK +RNEISPRQ +IR+REF+QAEVE+F+ N+ + P + + L N L++ G
Sbjct: 182 GKGFRNEISPRQALIRMREFSQAEVEVFYIEND-DFP----IPDSSVEL----NMLRNTG 232
Query: 253 -MIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEERAHYSADTW 311
++++ +A++ G + N AY+L +ILL +G D IR R+ P ERAHYS++TW
Sbjct: 233 DLLKMKVSDALRSGIIGNRVMAYFLNKTYEILLKLGFQPDHIRAREHDPGERAHYSSETW 292
Query: 312 DAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIVK 360
D E Y W E VG++ R YDL RH + SG + I PK+V+
Sbjct: 293 DFE-YLLDGDWTEIVGVSDRGTYDLGRHQQFSGENF--QIDGRTPKVVE 338
Score = 122 bits (302), Expect = 1e-26
Identities = 57/126 (45%), Positives = 86/126 (68%)
Query: 435 PHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAPIEVAVLPLVAKEPLTKIAYD 494
P V+EPS+G+DR ++++S E+G L++ ++PI +A+ PL ++ L KIA D
Sbjct: 334 PKVVEPSYGLDRILLTIMDSSYYRRENGYKVLRLDPHISPIHMAIFPLQKRDDLDKIAKD 393
Query: 495 LFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDGTVTIRDRDTREQIR 554
LF K++ + YD+ +IG+RY R DEIGTP+CVT+D QT D TVTIR+RD+ Q+R
Sbjct: 394 LFEKMKNIDPFIFYDDSGNIGRRYARQDEIGTPFCVTVDYQTKDDETVTIRERDSTSQVR 453
Query: 555 VKLEDV 560
VK+ D+
Sbjct: 454 VKISDL 459
>pir||C75320 glycyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459849|gb|AAF11606.1|AE002042_1 (AE002042)
glycyl-tRNA synthetase [Deinococcus radiodurans]
Length = 521
Score = 258 bits (653), Expect = 1e-67
Identities = 196/594 (32%), Positives = 271/594 (44%), Gaps = 145/594 (24%)
Query: 9 EYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKI--REAFIREGFFEIET 66
E L L +RRGF + EIYGG +GFYDYGPLG +K I+ + R+ ++
Sbjct: 22 EELVSLCKRRGFIFQGSEIYGGLQGFYDYGPLGVELKNNIKAAWWRSNVYERDDMEGLDA 81
Query: 67 PDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEM------ 120
I V SGH F DP+++ KK R+R DHL+++ DV+ K AE M
Sbjct: 82 SIIMHRMVLRHSGHEATFSDPMIDNKKNNKRYRLDHLLKDQKA-DVQAKVAEIMGESADN 140
Query: 121 ---------------TKIIREHNIKCPECG--GELGDVFYFNLMFETYIGPYKDKKAY-- 161
+ +E ++ P G GE D FN+MF T IGP D+++Y
Sbjct: 141 FAALVAALNAKPAQASAAFKEAGVRDPFSGEVGEWTDPKPFNMMFRTTIGPVADEESYGY 200
Query: 162 LRPETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFF 221
LRPETAQGIF NFK + +LPFG+ QIGKA+RNEI+PR + R+RE Q E+E F
Sbjct: 201 LRPETAQGIFTNFKNVVDSTSRRLPFGIAQIGKAFRNEITPRNFIFRVRELEQMEIEFFV 260
Query: 222 NPNETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKK 281
P DE HE ++L K
Sbjct: 261 TPGT------DEEWHE------------------------------------HWLEKRLK 278
Query: 282 ILLDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMK 341
D G+P +KI E+ AHYS T+D G E G+A R+DYDL H K
Sbjct: 279 WWEDQGVPREKIEILDVPKEDLAHYSKRTYDLMYDYPTLGHEEIEGIANRSDYDLGSHTK 338
Query: 342 MSGADLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKL 401
S+ EL LV K+
Sbjct: 339 ------------------------------------------------SQSEL-GLVAKV 349
Query: 402 NEEGKIVIDGYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTID-- 459
E + D + T + ++P V+EPS G+DR +L + T +
Sbjct: 350 EE-----------NNDSIAKLTIPHPETNKPVVPFVIEPSAGVDRAMLAVLSEAFTKETL 398
Query: 460 EDG--RIYLKIKKDMAPIEVAVLPLVA-KEPLTKIAYDLFRKLQKEGF-IVVYDEKDSIG 515
E+G RI LK+K +API+VAV+PL +E +T +A + +LQ G V+Y++ +IG
Sbjct: 399 ENGNERIVLKLKPHLAPIKVAVIPLARNREEITDVAKAIKAELQGLGLGRVLYEDSGNIG 458
Query: 516 KRYMRYDEIGTPYCVTIDNQT---------PIDGTVTIRDRDTREQIRVKLEDV 560
K Y R+DE+GTPYCVT+D T + TVT+RDRDT Q RVK+ ++
Sbjct: 459 KAYRRHDEVGTPYCVTVDFDTVGLGENTDESLKDTVTVRDRDTLAQERVKISEL 512
>sp|Q9RSR5|SYG_DEIRA GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
Length = 506
Score = 258 bits (653), Expect = 1e-67
Identities = 196/594 (32%), Positives = 271/594 (44%), Gaps = 145/594 (24%)
Query: 9 EYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKI--REAFIREGFFEIET 66
E L L +RRGF + EIYGG +GFYDYGPLG +K I+ + R+ ++
Sbjct: 7 EELVSLCKRRGFIFQGSEIYGGLQGFYDYGPLGVELKNNIKAAWWRSNVYERDDMEGLDA 66
Query: 67 PDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEM------ 120
I V SGH F DP+++ KK R+R DHL+++ DV+ K AE M
Sbjct: 67 SIIMHRMVLRHSGHEATFSDPMIDNKKNNKRYRLDHLLKDQKA-DVQAKVAEIMGESADN 125
Query: 121 ---------------TKIIREHNIKCPECG--GELGDVFYFNLMFETYIGPYKDKKAY-- 161
+ +E ++ P G GE D FN+MF T IGP D+++Y
Sbjct: 126 FAALVAALNAKPAQASAAFKEAGVRDPFSGEVGEWTDPKPFNMMFRTTIGPVADEESYGY 185
Query: 162 LRPETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFF 221
LRPETAQGIF NFK + +LPFG+ QIGKA+RNEI+PR + R+RE Q E+E F
Sbjct: 186 LRPETAQGIFTNFKNVVDSTSRRLPFGIAQIGKAFRNEITPRNFIFRVRELEQMEIEFFV 245
Query: 222 NPNETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKK 281
P DE HE ++L K
Sbjct: 246 TPGT------DEEWHE------------------------------------HWLEKRLK 263
Query: 282 ILLDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMK 341
D G+P +KI E+ AHYS T+D G E G+A R+DYDL H K
Sbjct: 264 WWEDQGVPREKIEILDVPKEDLAHYSKRTYDLMYDYPTLGHEEIEGIANRSDYDLGSHTK 323
Query: 342 MSGADLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKL 401
S+ EL LV K+
Sbjct: 324 ------------------------------------------------SQSEL-GLVAKV 334
Query: 402 NEEGKIVIDGYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTID-- 459
E + D + T + ++P V+EPS G+DR +L + T +
Sbjct: 335 EE-----------NNDSIAKLTIPHPETNKPVVPFVIEPSAGVDRAMLAVLSEAFTKETL 383
Query: 460 EDG--RIYLKIKKDMAPIEVAVLPLVA-KEPLTKIAYDLFRKLQKEGF-IVVYDEKDSIG 515
E+G RI LK+K +API+VAV+PL +E +T +A + +LQ G V+Y++ +IG
Sbjct: 384 ENGNERIVLKLKPHLAPIKVAVIPLARNREEITDVAKAIKAELQGLGLGRVLYEDSGNIG 443
Query: 516 KRYMRYDEIGTPYCVTIDNQT---------PIDGTVTIRDRDTREQIRVKLEDV 560
K Y R+DE+GTPYCVT+D T + TVT+RDRDT Q RVK+ ++
Sbjct: 444 KAYRRHDEVGTPYCVTVDFDTVGLGENTDESLKDTVTVRDRDTLAQERVKISEL 497
>gb|AAG10609.1|AC008030_9 (AC008030) Putative glycyl-tRNA synthetase [Arabidopsis thaliana]
Length = 464
Score = 249 bits (630), Expect = 5e-65
Identities = 154/408 (37%), Positives = 220/408 (53%), Gaps = 24/408 (5%)
Query: 3 ERFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI-REGF 61
+R D E + + R F SF+IY G G YD+GP G T++ I R+ F+ E
Sbjct: 56 DREDFREAVVKTLDRLLFVHKSFDIYHGVAGLYDFGPHGRTVELNILSLWRKCFVDEEDM 115
Query: 62 FEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIE---ETLGID--VEGKS 116
E+ +TPE VF ASGHV+KF D +V+ + GA RADHL++ E D + ++
Sbjct: 116 MEVACTALTPEAVFNASGHVKKFTDLMVKDEVDGAFHRADHLVKSYCENRKKDPTISAEN 175
Query: 117 AEEMTKIIRE-HNIKCPECGGELGDVFY--------------FNLMFETYIGPYKDKKAY 161
A E+ K+I ++ E GG FNLMF+T G Y
Sbjct: 176 AAELDKVIAHVEDLSAEELGGVWNHCSTAPVTKNPLSHPPRPFNLMFQTSFGASGSLIGY 235
Query: 162 LRPETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFF 221
LRPETAQG F NFK KLPF V Q+G+ +RNEISPRQG++R REFT AE+E F
Sbjct: 236 LRPETAQGSFCNFKDYYNLNGRKLPFAVAQVGRVFRNEISPRQGLLRTREFTLAEIEHFV 295
Query: 222 NPNETEHPHFDEVKHEKLRLYPIENQLKDLGMIE-LTAEEAVKKGYLMNT-FFAYYLVMI 279
+P H F +V +L ++P E Q K + L EAV K +N+ +++ +
Sbjct: 296 HPEHKSHSKFSDVAKLELLMFPREEQEKPGQFAKRLCLGEAVAKVRHVNSETLGFFIGRV 355
Query: 280 KKILLDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRH 339
L+ +GI ++++RFR L E AHY+ D WDAE+ +GW+ECVG+A R+DYDL H
Sbjct: 356 YLFLIRLGIDKERLRFRHHLANEMAHYATDCWDAEIECS-YGWIECVGIADRSDYDLRAH 414
Query: 340 MKMSGADLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQ 387
+ SG L +P V++L ++ MK +GP K + K + E ++
Sbjct: 415 SEKSGHALVAQEKLAEPIEVEKLAITPEMKELGPAFKGNQKNVVEALE 462
>gb|AAC71652.1| (AC004976) glycyl tRNA synthetase [Homo sapiens]
Length = 392
Score = 213 bits (536), Expect = 5e-54
Identities = 126/368 (34%), Positives = 201/368 (54%), Gaps = 14/368 (3%)
Query: 215 AEVEIFFNPNETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAY 274
AE+E F +P+E +HP F V L LY + Q+ ++ +AV++G + NT Y
Sbjct: 2 AEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGY 61
Query: 275 YLVMIKKILLDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDY 334
++ I L +GI DK+RFRQ + E AHY+ D WDAE + +GW+E VG A R+ Y
Sbjct: 62 FIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTS-YGWIEIVGCADRSCY 120
Query: 335 DLSRHMKMSGADLTVMIHYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEEL 394
DLS H + + L +PK V ++ + ++G KKDAK + E + E +
Sbjct: 121 DLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYI 180
Query: 395 RELVKKLNEEGKIVID----GYELSKDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYL 450
E+ LNE+G+ I+ ++L+KD +K ++ + E+++P+V+EPSFG+ R Y
Sbjct: 181 TEMEMLLNEKGEFTIETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYT 240
Query: 451 LLENSLTIDE--DGRIYLKIKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQKEGFI-VV 507
+ E++ + E + R + +AP + +VLPL + +L L + G V
Sbjct: 241 VFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKV 300
Query: 508 YDEKDSIGKRYMRYDEIGTPYCVTID----NQTPIDGTVTIRDRDTREQIRVKLEDVPRK 563
D SIG+RY R DEIG + VTID N+TP T T+RDRD+ QIR ++ ++P
Sbjct: 301 DDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTP--HTATLRDRDSMRQIRAEISELPSI 358
Query: 564 LKELIFGS 571
+++L G+
Sbjct: 359 VQDLANGN 366
>sp|Q9PPZ7|SYG_UREPA GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|11271564|pir||D82884 glycyl-tRNA synthetase UU493
[imported] - Ureaplasma urealyticum
>gi|6899491|gb|AAF30905.1|AE002147_6 (AE002147)
glycyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 473
Score = 207 bits (521), Expect = 3e-52
Identities = 173/582 (29%), Positives = 263/582 (44%), Gaps = 137/582 (23%)
Query: 1 MGERFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI--R 58
M +F E L + ++ GF + + EIY G +DYGPLG +K ++ + F+ +
Sbjct: 1 MRYKFKTQEDLVNHLKSVGFVFANSEIYNGLANAWDYGPLGVLLKNNLKNLWWKEFVTKQ 60
Query: 59 EGFFEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDV---EGK 115
+ +++ I V+ ASGH++ F DP+++CK C R+RAD LIE + D+ E
Sbjct: 61 KNIVGLDSAIILNPLVWKASGHLDNFSDPLIDCKSCKTRYRADKLIE-SFNKDIHIAENS 119
Query: 116 SAEEMTKIIREHNIKCPECGG-ELGDVFYFNLMFETYIGPYKDKK--AYLRPETAQGIFV 172
+ EE K++ +H I CP C D+ +FNLMF+T+ G +D K YLRPETAQGIFV
Sbjct: 120 TNEEFMKVLNDHKIFCPTCKQFNWTDIRHFNLMFKTHQGVIEDPKNIVYLRPETAQGIFV 179
Query: 173 NFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFD 232
NFK + R LPFG+ QIGK++RNEI+P + R REF Q E+E FF E + FD
Sbjct: 180 NFKNVQRSMRLHLPFGIAQIGKSFRNEITPGNFIFRTREFEQMEIE-FFLKEEIAYDVFD 238
Query: 233 EVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLD-IGIPED 291
+ YL I+ L+ G+ +
Sbjct: 239 K-----------------------------------------YLNQIQNWLVTCCGLDLN 257
Query: 292 KIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMI 351
+R + EE +HYS T D E Y+ G+ E G+AYRT+YDLS HM +S DLT
Sbjct: 258 NLRKHEHPKEELSHYSKKTIDFE-YNFLHGFSELYGIAYRTNYDLSVHMNLSKKDLTYFD 316
Query: 352 HYDKPKIVKRLKVSLNMKSVGPKLKKDAKRINEKIQAMSEEELRELVKKL-NEEGKIVID 410
K K + P + + + + + A+ E ++KL N+E +I+++
Sbjct: 317 EETKQKYI-------------PHVIEPSVGVERLLYAILTE--ATFIEKLANDEDRILMN 361
Query: 411 -GYELSKDDFIIKEVEEKV--TGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLK 467
Y+L+ + + K+ E + +L+ L S+T D G I +
Sbjct: 362 LKYDLAPYKIAVMPLVNKLKEKAEAVYNKILD------------LNISVTFDNSGSIGKR 409
Query: 468 IKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTP 527
Y +D+IG T
Sbjct: 410 ----------------------------------------YRRQDAIG----------TI 419
Query: 528 YCVTIDNQT---PIDGTVTIRDRDTREQIRVKLEDVPRKLKE 566
YC+TID + D T TIR+R+T Q R+KL ++ L +
Sbjct: 420 YCITIDYDSFGDEHDPTFTIRERNTMAQKRIKLSELSLYLSQ 461
>sp|O51344|SYG_BORBU GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|7428472|pir||B70146 glycine--tRNA ligase (EC
6.1.1.14) glyS - Lyme disease spirochete
>gi|2688266|gb|AAC66743.1| (AE001142) glycyl-tRNA
synthetase (glyS) # [Borrelia burgdorferi]
Length = 445
Score = 203 bits (512), Expect = 3e-51
Identities = 164/570 (28%), Positives = 255/570 (43%), Gaps = 150/570 (26%)
Query: 7 KYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREA--FIREGFFEI 64
+ E + L +R+GF + S E+YGG G +DYGPLG +K+ I+K+ ++ ++ E +
Sbjct: 3 RMEDIISLAKRKGFVFQSSEVYGGLSGAWDYGPLGVELKKNIKKEWWKSMVYLHENIVGL 62
Query: 65 ETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEMTKII 124
++ +++ ASGHV+ F D +V+CK C +RFRAD + +++K
Sbjct: 63 DSAIFMRPEIWRASGHVDGFSDSMVDCKDCKSRFRADFI---------------DLSK-- 105
Query: 125 REHNIKCPEC--GGELGDVFYFNLMFETYIGPYKDKKA--YLRPETAQGIFVNFKRLNAF 180
CP C G FNLMF+T+IG +D + YLRPETAQGIFVNF+ +
Sbjct: 106 -----NCPNCKVGNNFTSPRSFNLMFKTHIGVVEDSSSEVYLRPETAQGIFVNFRNVLDS 160
Query: 181 ARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLR 240
+R K+PFG+ Q+GKA+RNEI + + R EF Q E++ F +P +
Sbjct: 161 SRLKIPFGIAQVGKAFRNEIVTKNFIFRTCEFEQMEMQFFVHPKQ--------------- 205
Query: 241 LYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLD-IGIPEDKIRFRQQL 299
++ +F Y+ ++ + I D++RF+
Sbjct: 206 ---------------------------IDEWFCYWQQNRMNFFIETLKISPDRLRFKAHD 238
Query: 300 PEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADLTVMIHYDKPKIV 359
+ AHY+ +D E Y FG+ E G+ R +YDL++H K S +KPK+
Sbjct: 239 STQLAHYAKAAFDIE-YEFPFGFQEVEGIHNRGNYDLTQHAKFS----------NKPKVF 287
Query: 360 KRLKVSLNMKSVGPKLKKDAKRINEKI----QAMSEEELRELVKKLNEEGKIVIDGYELS 415
+ + K V ++ A + A SEEEL DG
Sbjct: 288 EYHDLLTKEKYVPYVIETSAGLTRSVLMTLCDAYSEEELS--------------DG---- 329
Query: 416 KDDFIIKEVEEKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDEDGRIYLKIKKDMAPI 475
D I+ + K+ KI + L++ + RIY+++ D
Sbjct: 330 -DKRIVLRLHPKLAPYKI-------------AIFPLVKKVELTEIARRIYMELCDDF--- 372
Query: 476 EVAVLPLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQ 535
I YD + +IGKRY R DEIGTPYCVTID
Sbjct: 373 --------------HIFYD---------------DSGTIGKRYRRQDEIGTPYCVTIDYN 403
Query: 536 TPIDGTVTIRDRDTREQIRVKLEDVPRKLK 565
T D TVT+R+R++ Q R+ + D+ +K
Sbjct: 404 TIEDETVTVRERNSMTQKRIFINDLYSYIK 433
>sp|Q9L2H9|SYG_STRCO GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|6752347|emb|CAB69725.1| (AL137166) glycyl-tRNA
synthetase [Streptomyces coelicolor A3(2)]
Length = 460
Score = 199 bits (500), Expect = 9e-50
Identities = 132/362 (36%), Positives = 182/362 (49%), Gaps = 68/362 (18%)
Query: 6 DKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI--REGFFE 63
DK + + L +RRGF + EIYGG R +DYGPLG +K ++++ + RE
Sbjct: 4 DKIDTIVSLSKRRGFVFPCSEIYGGQRAAWDYGPLGVELKENLKRQWWRYMVTSREDVVG 63
Query: 64 IETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHL---IEETLGIDVEGKSAEEM 120
+++ I +V++ASGHV F DP+ EC C RFRADHL EE G E A+
Sbjct: 64 LDSSVILAPEVWVASGHVATFTDPLTECTSCHKRFRADHLEEAYEEKKGHAPENGLAD-- 121
Query: 121 TKIIREHNIKCPECG--GELGDVFYFNLMFETYIGPYKDKK--AYLRPETAQGIFVNFKR 176
+ CP CG G + F+ + T++GP +D AYLRPETAQGIF NF +
Sbjct: 122 --------LNCPNCGNKGTFTEPKQFSGLLSTHLGPTQDSGSVAYLRPETAQGIFTNFAQ 173
Query: 177 LNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKH 236
+ +R K PFG+ Q+GK++RNEI+P + R REF Q E+E F P E DE
Sbjct: 174 VQTTSRRKPPFGIAQMGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGE------DEKWQ 227
Query: 237 EKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFR 296
E Y M + +Y +G+ E+ +R+
Sbjct: 228 E----------------------------YWMEQRWNWY--------TGLGLREENMRWY 251
Query: 297 QQLPEERAHYSADTWDAEVYSERFG---WVECVGLAYRTDYDLSRHMKMSGADLTVMIHY 353
+ E+ +HYS T D E Y FG W E G+A RTDYDLS H K SG DL+ +Y
Sbjct: 252 EHPAEKLSHYSKRTADIE-YRFSFGGSEWGELEGVANRTDYDLSSHAKASGQDLS---YY 307
Query: 354 DK 355
D+
Sbjct: 308 DQ 309
Score = 94.4 bits (231), Expect = 3e-18
Identities = 53/148 (35%), Positives = 85/148 (56%), Gaps = 9/148 (6%)
Query: 431 EKIIPHVLEPSFGIDRPFYLLLENSLTIDE--------DGRIYLKIKKDMAPIEVAVLPL 482
E+ P+V+EP+ G+ R L ++ DE + R L++ ++P++VAVLPL
Sbjct: 313 ERWTPYVIEPAAGVGRAMLAFLLDAYIEDEAPNAKGKLEKRTVLRLDPRLSPVKVAVLPL 372
Query: 483 VAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDGTV 542
L+ A L + L ++ + + +D+ +IG+RY R DEIGTP+CVT+D T D V
Sbjct: 373 SRNPELSPKAKGLAQAL-RQNWNIEFDDAGAIGRRYRRQDEIGTPFCVTVDFDTLDDNAV 431
Query: 543 TIRDRDTREQIRVKLEDVPRKLKELIFG 570
T+R+RDT +Q RV L+ + L + G
Sbjct: 432 TVRERDTMKQERVSLDQIEGYLASRLVG 459
>sp|O65932|SYG_MYCTU GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|7428473|pir||D70585 probable glyS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2078043|emb|CAB08466.1| (Z95208) glyS [Mycobacterium
tuberculosis]
Length = 463
Score = 190 bits (479), Expect = 3e-47
Identities = 127/347 (36%), Positives = 183/347 (52%), Gaps = 63/347 (18%)
Query: 13 DLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFI--REGFFEIETPDIT 70
+L +RRGF + S EIYGG++ +DYGPLG +K I+++ + + R+ I++ I
Sbjct: 14 NLAKRRGFVYPSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVVTGRDDVVGIDSSIIL 73
Query: 71 PEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEMTKIIREHNIK 130
P +V++ASGHV+ F DP+VE R+RADHLIE E K + + I+
Sbjct: 74 PREVWVASGHVDVFHDPLVESLITHKRYRADHLIEA-----YEAKHGHPPPNGLAD--IR 126
Query: 131 CPECG--GELGDVFYFNLMFETYIGPYKDKKA--YLRPETAQGIFVNFKRLNAFARNKLP 186
PE G G+ FN+M +TY+GP + ++ YLRPETAQGIFVNF + AR K P
Sbjct: 127 DPETGEPGQWTQPREFNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVVTTARKKPP 186
Query: 187 FGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPIEN 246
FG+ QIGK++RNEI+P + R REF Q E+E F P + H Y I+N
Sbjct: 187 FGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPATAKEWH----------QYWIDN 236
Query: 247 QLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEERAHY 306
+L+ +Y +D+GI + +R + ++ +HY
Sbjct: 237 RLQ------------------------WY--------IDLGIRRENLRLWEHPKDKLSHY 264
Query: 307 SADTWDAEVYSERFG-----WVECVGLAYRTDYDLSRHMKMSGADLT 348
S T D E +FG W E G+A RTD+DLS H + SG DL+
Sbjct: 265 SDRTVDIEY---KFGFMGNPWGELEGVANRTDFDLSTHARHSGVDLS 308
Score = 94.8 bits (232), Expect = 2e-18
Identities = 55/154 (35%), Positives = 87/154 (55%), Gaps = 9/154 (5%)
Query: 426 EKVTGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE--------DGRIYLKIKKDMAPIEV 477
+++ + P+V+EP+ G+ R F L ++ T DE D R L++ +AP++
Sbjct: 311 DQINDVRYTPYVIEPAAGLTRSFMAFLIDAYTEDEAPNTKGGMDKRTVLRLDPRLAPVKA 370
Query: 478 AVLPLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTP 537
AVLPL L+ A DL +L+K + + +D+ +IG+RY R DE+GTP+CVT+D +
Sbjct: 371 AVLPLSRHADLSPKARDLGAELRK-CWNIDFDDAGAIGRRYRRQDEVGTPFCVTVDFDSL 429
Query: 538 IDGTVTIRDRDTREQIRVKLEDVPRKLKELIFGS 571
D VT+R+RD Q RV + V L + GS
Sbjct: 430 QDNAVTVRERDAMTQDRVAMSSVADYLAVRLKGS 463
>emb|CAB40582.1| (AJ010128) glycyl-tRNA synthetase [Bacillus cereus]
Length = 217
Score = 180 bits (452), Expect = 4e-44
Identities = 95/213 (44%), Positives = 137/213 (63%), Gaps = 10/213 (4%)
Query: 9 EYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIREGFFEI--ET 66
E + +L + RGF + EIYGG +DYGPLG +K ++K + FI+E + + +
Sbjct: 5 EQVVNLAKHRGFVFPGSEIYGGLANTWDYGPLGIELKNNVKKAWWKKFIQESPYNVGLDA 64
Query: 67 PDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETL---GID--VEGKSAEEMT 121
+ + +IASGHV F DP+++CKKC AR RAD LIE+ L GI+ V+G + ++M
Sbjct: 65 AILMNPKTWIASGHVGNFNDPMIDCKKCKARHRADKLIEDALDAKGIEMVVDGLTFDQMA 124
Query: 122 KIIREHNIKCPECGGE-LGDVFYFNLMFETYIGPYKDK--KAYLRPETAQGIFVNFKRLN 178
+++EH +KCP+CG E ++ FNLMF+T+ G + + +LRPETAQGIFVNFK +
Sbjct: 125 DLMKEHEVKCPDCGSEEFTEIRQFNLMFKTFQGVTESSTNEIFLRPETAQGIFVNFKNVQ 184
Query: 179 AFARNKLPFGVFQIGKAYRNEISPRQGMIRLRE 211
R KLPFG+ QIGK++RNEI+P R RE
Sbjct: 185 RSMRKKLPFGIGQIGKSFRNEITPGNFTFRTRE 217
>sp|O83678|SYG_TREPA GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|7428471|pir||C71296 glycine--tRNA ligase (EC
6.1.1.14) (glyS) - syphilis spirochete
>gi|3322974|gb|AAC26570.1| (AE001241) glycyl-tRNA
synthetase (glyS) [Treponema pallidum]
Length = 462
Score = 177 bits (444), Expect = 3e-43
Identities = 114/343 (33%), Positives = 161/343 (46%), Gaps = 66/343 (19%)
Query: 9 EYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIR--EGFFEIET 66
E + L +RRGF + S EIYGG G +DYGP+G +K I + R + ++
Sbjct: 2 EKIVGLCKRRGFVFPSSEIYGGQGGVWDYGPMGIALKNNIAHAWWQDMTRLHDHIVGLDA 61
Query: 67 PDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEMTKIIRE 126
+ V+ SGHV+ F DP+V+C C +RFRAD + + G
Sbjct: 62 AILMHPNVWRTSGHVDHFSDPLVDCTVCKSRFRADQVAVPSAGGP--------------- 106
Query: 127 HNIKCPECGGELGDVFYFNLMFETYIGPYKDKKA--YLRPETAQGIFVNFKRLNAFARNK 184
CP+CGG L V FNLMF T++GP ++ + YLRPETAQGI+VN+K + R K
Sbjct: 107 ----CPQCGGALTGVRNFNLMFSTHMGPTDERASLLYLRPETAQGIYVNYKNVLQTTRLK 162
Query: 185 LPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPI 244
+PFG+ QIGKA+RNEI + + R EF Q E++ F P E H
Sbjct: 163 VPFGIAQIGKAFRNEIVTKNFIFRTCEFEQMEMQFFVRPAEDTH---------------- 206
Query: 245 ENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEERA 304
+F Y+ G+ + +R+R E A
Sbjct: 207 --------------------------WFEYWCAQRWAFYQKYGVRMNHMRWRTHAAHELA 240
Query: 305 HYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMSGADL 347
HY+ D E Y+ G+ E G+ R D+DL+RH + SG DL
Sbjct: 241 HYARAACDIE-YAFPMGFRELEGVHNRGDFDLTRHAQHSGKDL 282
Score = 83.9 bits (204), Expect = 5e-15
Identities = 54/148 (36%), Positives = 79/148 (52%), Gaps = 25/148 (16%)
Query: 432 KIIPHVLEPSFGIDRPFYLLL-----------------ENSLTIDEDG-------RIYLK 467
+ +P V+E S G+ R + L E + T D++G RI L+
Sbjct: 297 RYVPCVVETSAGLTRCVLMFLCDAYTEEYVQAPNVAFSETTQTADQEGAARTGEMRIVLR 356
Query: 468 IKKDMAPIEVAVLPLVAKEPLTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTP 527
+ ++P VA LPLV K+ L +A + +L +E F +D +IGKRY R DE+GTP
Sbjct: 357 LHPALSPTTVAFLPLVKKDGLVDLARAVRDEL-REDFACDFDAAGAIGKRYRRQDEVGTP 415
Query: 528 YCVTIDNQTPIDGTVTIRDRDTREQIRV 555
+CVT+D Q+ D TVT+R RD+ Q RV
Sbjct: 416 FCVTVDYQSKEDDTVTVRLRDSMAQRRV 443
>sp|P75425|SYG_MYCPN GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|2146142|pir||S73808 glycine--tRNA ligase (EC
6.1.1.14) grs1 - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1674173|gb|AAB96130.1| (AE000047) glycyl-tRNA
synthetase [Mycoplasma pneumoniae]
Length = 449
Score = 169 bits (424), Expect = 7e-41
Identities = 96/228 (42%), Positives = 134/228 (58%), Gaps = 17/228 (7%)
Query: 1 MGERFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIRE- 59
M + + + Y+Q L +R GF + S E+Y G +D+GPLGA +K++I+ + FI+
Sbjct: 1 MAQVYSQEVYVQYL-KRYGFVFQSSELYNGLANSWDFGPLGAVLKQQIKTALYNFFIKNK 59
Query: 60 -GFFEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAE 118
I+TP I EQ++ ASGH+ F D +V+CK C RFR DHL E+ KSA
Sbjct: 60 RDVLLIDTPIILNEQIWKASGHLANFTDALVDCKSCKLRFRVDHLDEQI-------KSAT 112
Query: 119 EMTKIIREHNIKCPEC-GGELGDVFYFNLMFETYIGPYKDKK--AYLRPETAQGIFVNFK 175
+ + CP C +V FNL+F+T IG +K YLRPETAQGIF+NFK
Sbjct: 113 QWNP----KQVNCPNCKANNWSEVRDFNLLFQTEIGVVNSEKRLVYLRPETAQGIFINFK 168
Query: 176 RLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNP 223
+L + LPFGV Q GK++RNE++P + R+REF Q E+E F NP
Sbjct: 169 QLLQLKKRPLPFGVAQFGKSFRNEVTPGNFLFRVREFEQFEMEWFCNP 216
Score = 88.2 bits (215), Expect = 2e-16
Identities = 50/133 (37%), Positives = 81/133 (60%), Gaps = 5/133 (3%)
Query: 431 EKIIPHVLEPSFGIDRPFYLLLENSLT---IDEDGRIYLKIKKDMAPIEVAVLPLVAKEP 487
E IP V+EPS GI+R FY L+ +S ++ + R L++ + P ++ VLPLV K
Sbjct: 307 EHFIPAVVEPSVGIERLFYALIVSSYQQEQLEGEMREVLRLPFHLCPEQIVVLPLVNK-- 364
Query: 488 LTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDGTVTIRDR 547
L + A LF L + + + ++ SIGKRY + D IGT + +T D ++ D VTIR+R
Sbjct: 365 LKETAQTLFEALSQTHWRIGFESAGSIGKRYRKADAIGTKFAITFDFESLEDQAVTIRER 424
Query: 548 DTREQIRVKLEDV 560
D+ +Q+RV ++++
Sbjct: 425 DSLKQVRVPIKEL 437
>pdb|1ATI|A Chain A, Crystal Structure Of Glycyl-Trna Synthetase From Thermus
Thermophilus >gi|2392170|pdb|1ATI|B Chain B, Crystal
Structure Of Glycyl-Trna Synthetase From Thermus
Thermophilus
Length = 505
Score = 168 bits (422), Expect = 1e-40
Identities = 123/358 (34%), Positives = 170/358 (47%), Gaps = 77/358 (21%)
Query: 14 LMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKI--REAFIREGFFEIETPDITP 71
L +RRGF + S EIYGG +G YDYGPLG +K +++ R + R+ ++ +T
Sbjct: 11 LCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNVYERDDMEGLDASVLTH 70
Query: 72 EQVFIASGHVEKFVDPIVECKKCGARFRADHLIEET---------LGIDVEGKSAEEMTK 122
V SGH F DP+V+ + R+R DHL++E ++VE EE
Sbjct: 71 RLVLHYSGHEATFADPMVDNRITKKRYRLDHLLKEQPEEVLKRLYRAMEVE----EENLH 126
Query: 123 IIREHNIKCPE--------------CGGELGDVF---YFNLMFETYIGPYKDKK--AYLR 163
+ + ++ PE GE GD YFN+MF+ GP + AYLR
Sbjct: 127 ALVQAMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRGPRGGRGLLAYLR 186
Query: 164 PETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNP 223
PETAQGIFVNFK + KL FG+ QIGKA+RNEI+PR + R+REF Q E+E F P
Sbjct: 187 PETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFRNEITPRNFIFRVREFEQMEIEYFVRP 246
Query: 224 NETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKIL 283
E E+ H Y +E +L K
Sbjct: 247 GEDEYWH----------RYWVEERL--------------------------------KWW 264
Query: 284 LDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMK 341
++G+ + + QQ PE AHY+ T D +Y G +E G+A RTD+DL H K
Sbjct: 265 QEMGLSRENLVPYQQPPESSAHYAKATVDI-LYRFPHGSLELEGIAQRTDFDLGSHTK 321
Score = 109 bits (270), Expect = 8e-23
Identities = 64/153 (41%), Positives = 95/153 (61%), Gaps = 15/153 (9%)
Query: 429 TGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE----DGRIYLKIKKDMAPIEVAVLPLVA 484
TG+ +P+V+EPS G+DR LL + T +E + RI LK+K +API+VAV+PLV
Sbjct: 349 TGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVK 408
Query: 485 KEP-LTKIAYDLFRKLQKEGF-IVVYDEKDSIGKRYMRYDEIGTPYCVTI---------D 533
P +T+ A L +L G V+Y++ +IGK Y R+DE+GTP+ VT+ D
Sbjct: 409 NRPEITEYAKRLKARLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKD 468
Query: 534 NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKE 566
T + TVT+RDRDT EQIR+ ++++ L+E
Sbjct: 469 GTTRLKDTVTVRDRDTMEQIRLHVDELEGFLRE 501
>sp|P56206|SYG_THETH GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
Length = 506
Score = 168 bits (422), Expect = 1e-40
Identities = 123/358 (34%), Positives = 170/358 (47%), Gaps = 77/358 (21%)
Query: 14 LMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKI--REAFIREGFFEIETPDITP 71
L +RRGF + S EIYGG +G YDYGPLG +K +++ R + R+ ++ +T
Sbjct: 12 LCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNVYERDDMEGLDASVLTH 71
Query: 72 EQVFIASGHVEKFVDPIVECKKCGARFRADHLIEET---------LGIDVEGKSAEEMTK 122
V SGH F DP+V+ + R+R DHL++E ++VE EE
Sbjct: 72 RLVLHYSGHEATFADPMVDNRITKKRYRLDHLLKEQPEEVLKRLYRAMEVE----EENLH 127
Query: 123 IIREHNIKCPE--------------CGGELGDVF---YFNLMFETYIGPYKDKK--AYLR 163
+ + ++ PE GE GD YFN+MF+ GP + AYLR
Sbjct: 128 ALVQAMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRGPRGGRGLLAYLR 187
Query: 164 PETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNP 223
PETAQGIFVNFK + KL FG+ QIGKA+RNEI+PR + R+REF Q E+E F P
Sbjct: 188 PETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFRNEITPRNFIFRVREFEQMEIEYFVRP 247
Query: 224 NETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKIL 283
E E+ H Y +E +L K
Sbjct: 248 GEDEYWH----------RYWVEERL--------------------------------KWW 265
Query: 284 LDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMK 341
++G+ + + QQ PE AHY+ T D +Y G +E G+A RTD+DL H K
Sbjct: 266 QEMGLSRENLVPYQQPPESSAHYAKATVDI-LYRFPHGSLELEGIAQRTDFDLGSHTK 322
Score = 109 bits (270), Expect = 8e-23
Identities = 64/153 (41%), Positives = 95/153 (61%), Gaps = 15/153 (9%)
Query: 429 TGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE----DGRIYLKIKKDMAPIEVAVLPLVA 484
TG+ +P+V+EPS G+DR LL + T +E + RI LK+K +API+VAV+PLV
Sbjct: 350 TGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVK 409
Query: 485 KEP-LTKIAYDLFRKLQKEGF-IVVYDEKDSIGKRYMRYDEIGTPYCVTI---------D 533
P +T+ A L +L G V+Y++ +IGK Y R+DE+GTP+ VT+ D
Sbjct: 410 NRPEITEYAKRLKARLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKD 469
Query: 534 NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKE 566
T + TVT+RDRDT EQIR+ ++++ L+E
Sbjct: 470 GTTRLKDTVTVRDRDTMEQIRLHVDELEGFLRE 502
>pir||S58522 glycine--tRNA ligase (EC 6.1.1.14) - Thermus aquaticus
Length = 506
Score = 168 bits (421), Expect = 2e-40
Identities = 123/358 (34%), Positives = 170/358 (47%), Gaps = 77/358 (21%)
Query: 14 LMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKI--REAFIREGFFEIETPDITP 71
L +RRGF + S EIYGG +G YDYGPLG +K +++ R + R+ ++ +T
Sbjct: 12 LCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNVYERDDMEGLDASVLTH 71
Query: 72 EQVFIASGHVEKFVDPIVECKKCGARFRADHLIEET---------LGIDVEGKSAEEMTK 122
V SGH F DP+V+ + R+R DHL++E ++VE EE
Sbjct: 72 RLVLHYSGHEATFADPMVDNRITKKRYRLDHLLKEQPEEVLKRLYRAMEVE----EENLH 127
Query: 123 IIREHNIKCPE--------------CGGELGDVF---YFNLMFETYIGPYKDKK--AYLR 163
+ + ++ PE GE GD YFN+MF+ GP + AYLR
Sbjct: 128 ALVQAMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRGPRGGRGLLAYLR 187
Query: 164 PETAQGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNP 223
PETAQGIFVNFK + KL FG+ QIGKA+RNEI+PR + R+REF Q E+E F P
Sbjct: 188 PETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFRNEITPRNFIFRVREFEQMEIEYFVRP 247
Query: 224 NETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKIL 283
E E+ H Y +E +L K
Sbjct: 248 GEDEYWH----------RYWVEERL--------------------------------KWW 265
Query: 284 LDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMK 341
++G+ + + QQ PE AHY+ T D +Y G +E G+A RTD+DL H K
Sbjct: 266 QEMGLSRENLVPYQQPPESSAHYAKATVDI-LYRFPHGSLELEGIANRTDFDLGSHTK 322
Score = 109 bits (270), Expect = 8e-23
Identities = 64/153 (41%), Positives = 95/153 (61%), Gaps = 15/153 (9%)
Query: 429 TGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE----DGRIYLKIKKDMAPIEVAVLPLVA 484
TG+ +P+V+EPS G+DR LL + T +E + RI LK+K +API+VAV+PLV
Sbjct: 350 TGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVK 409
Query: 485 KEP-LTKIAYDLFRKLQKEGF-IVVYDEKDSIGKRYMRYDEIGTPYCVTI---------D 533
P +T+ A L +L G V+Y++ +IGK Y R+DE+GTP+ VT+ D
Sbjct: 410 NRPEITEYAKRLKARLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKD 469
Query: 534 NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKE 566
T + TVT+RDRDT EQIR+ ++++ L+E
Sbjct: 470 GTTRLKDTVTVRDRDTMEQIRLHVDELEGFLRE 502
>sp|P47493|SYG_MYCGE GLYCYL-TRNA SYNTHETASE (GLYCINE--TRNA LIGASE) (GLYRS)
>gi|1361523|pir||G64227 glycine--tRNA ligase (EC
6.1.1.14) - Mycoplasma genitalium
>gi|3844849|gb|AAC71471.1| (U39704) glycyl-tRNA
synthetase [Mycoplasma genitalium]
Length = 446
Score = 167 bits (418), Expect = 4e-40
Identities = 111/349 (31%), Positives = 173/349 (48%), Gaps = 61/349 (17%)
Query: 1 MGERFDKYEYLQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIRE- 59
M + +++ Y+Q +++ GF + S EIY G +D+GPLGA +K++I++ + FI+
Sbjct: 1 MAKVYNQEVYVQ-FLKQHGFVFQSSEIYNGLNNSWDFGPLGAVLKQQIKQALYNFFIKNK 59
Query: 60 -GFFEIETPDITPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAE 118
+ETP I E V+ ASGH+ FVD +V+CK C RFR D I+ E K+ +
Sbjct: 60 ADVLLVETPIILSELVWKASGHLANFVDTLVDCKSCKYRFRVDQ-------INAEIKAKK 112
Query: 119 EMTKIIREHNIKCPECGGE-LGDVFYFNLMFETYIGPYKDKK--AYLRPETAQGIFVNFK 175
+ + CP C + +V FNL+F+T IG + K +LRPETAQG F+NFK
Sbjct: 113 DWNSF----KVNCPNCHNQNWSEVRDFNLLFQTEIGVVNNDKRLVFLRPETAQGSFINFK 168
Query: 176 RLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVK 235
+ + LPF + Q GK++RNEI+P + R REF Q E+E F P++
Sbjct: 169 NILQAKKRNLPFAIAQFGKSFRNEITPGNFLFRTREFEQFEIEWFCKPDDA--------- 219
Query: 236 HEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDI-GIPEDKIR 294
N+ F L+M+++ L + I + ++
Sbjct: 220 ---------------------------------NSLFEKQLIMVEQFLQTVLKINPELLK 246
Query: 295 FRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMKMS 343
+ E AHY+ T D +++ G E GLA R D+DL +H + S
Sbjct: 247 KHEYDQSELAHYAKKTTDF-LFNFPHGLKELWGLANRGDFDLKQHQEFS 294
Score = 96.7 bits (237), Expect = 6e-19
Identities = 54/135 (40%), Positives = 82/135 (60%), Gaps = 5/135 (3%)
Query: 431 EKIIPHVLEPSFGIDRPFYLLLENSLT---IDEDGRIYLKIKKDMAPIEVAVLPLVAKEP 487
+ +P ++EP+ GI+R FY L+ +S I+E+ R L + D+ P ++ VLPLV K
Sbjct: 307 QHFLPFIIEPAVGIERLFYALIVSSYRREIINEEEREVLSLPFDLCPEQIIVLPLVNK-- 364
Query: 488 LTKIAYDLFRKLQKEGFIVVYDEKDSIGKRYMRYDEIGTPYCVTIDNQTPIDGTVTIRDR 547
L K A+ +F L K + V ++ SIGKRY + D IG Y VT D ++ D VTIRDR
Sbjct: 365 LKKEAFSVFETLAKTRWRVCFETTGSIGKRYRKADAIGIKYAVTFDFESLEDNAVTIRDR 424
Query: 548 DTREQIRVKLEDVPR 562
DT Q R+ ++++P+
Sbjct: 425 DTLVQQRIAIKELPQ 439
>pdb|1B76|A Chain A, Glycyl-Trna Synthetase From Thermus Thermophilus Complexed
With Atp >gi|4388931|pdb|1GGM|A Chain A, Glycyl-Trna
Synthetase From Thermus Thermophilus Complexed With
Glycyl-Adenylate >gi|4388930|pdb|1B76|B Chain B,
Glycyl-Trna Synthetase From Thermus Thermophilus
Complexed With Atp >gi|4388932|pdb|1GGM|B Chain B,
Glycyl-Trna Synthetase From Thermus Thermophilus
Complexed With Glycyl-Adenylate
Length = 442
Score = 147 bits (368), Expect = 3e-34
Identities = 110/332 (33%), Positives = 148/332 (44%), Gaps = 88/332 (26%)
Query: 14 LMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKI--REAFIREGFFEIETPDITP 71
L +RRGF + S EIYGG +G YDYGPLG +K +++ R + R+ ++ +T
Sbjct: 11 LCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNVYERDDMEGLDASVLTH 70
Query: 72 EQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETLGIDVEGKSAEEMTKIIREHNIKC 131
V SGH F DP+V+ K AR+
Sbjct: 71 RLVLHYSGHEATFADPMVDNAK--ARYWTPPR---------------------------- 100
Query: 132 PECGGELGDVFYFNLMFETYIGPYKDKK--AYLRPETAQGIFVNFKRLNAFARNKLPFGV 189
YFN+MF+ GP + AYLRPETAQGIFVNFK + KL FG+
Sbjct: 101 -----------YFNMMFQDLRGPRGGRGLLAYLRPETAQGIFVNFKNVLDATSRKLGFGI 149
Query: 190 FQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETEHPHFDEVKHEKLRLYPIENQLK 249
QIGKA+RNEI+PR + R+REF Q E+E F P E E+ H Y +E +L
Sbjct: 150 AQIGKAFRNEITPRNFIFRVREFEQMEIEYFVRPGEDEYWH----------RYWVEERL- 198
Query: 250 DLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIGIPEDKIRFRQQLPEERAHYSAD 309
K ++G+ + + QQ PE AHY+
Sbjct: 199 -------------------------------KWWQEMGLSRENLVPYQQPPESSAHYAKA 227
Query: 310 TWDAEVYSERFGWVECVGLAYRTDYDLSRHMK 341
T D +Y G +E G+A RTD+DL H K
Sbjct: 228 TVDI-LYRFPHGSLELEGIAQRTDFDLGSHTK 258
Score = 109 bits (270), Expect = 8e-23
Identities = 64/153 (41%), Positives = 95/153 (61%), Gaps = 15/153 (9%)
Query: 429 TGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE----DGRIYLKIKKDMAPIEVAVLPLVA 484
TG+ +P+V+EPS G+DR LL + T +E + RI LK+K +API+VAV+PLV
Sbjct: 286 TGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVK 345
Query: 485 KEP-LTKIAYDLFRKLQKEGF-IVVYDEKDSIGKRYMRYDEIGTPYCVTI---------D 533
P +T+ A L +L G V+Y++ +IGK Y R+DE+GTP+ VT+ D
Sbjct: 346 NRPEITEYAKRLKARLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKD 405
Query: 534 NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKE 566
T + TVT+RDRDT EQIR+ ++++ L+E
Sbjct: 406 GTTRLKDTVTVRDRDTMEQIRLHVDELEGFLRE 438
>emb|CAA10903.1| (AJ222643) Glycyl-tRNA synthetase [Thermus thermophilus]
Length = 506
Score = 140 bits (350), Expect = 3e-32
Identities = 112/354 (31%), Positives = 157/354 (43%), Gaps = 69/354 (19%)
Query: 14 LMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKI--REAFIREGFFEIETPDITP 71
L +RRGF + S EIYGG +G YDYGPLG +K +++ R + R+ ++ +T
Sbjct: 12 LCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNVYERDDMEGLDASVLTH 71
Query: 72 EQVFIASGHVEKFVDPIVECKKCGARFRADHLIEET-----LGIDVEGKSAEEMTKIIRE 126
V SGH F DP+V+ + R+R DHL++E + + EE + +
Sbjct: 72 RLVLHYSGHEATFADPMVDNRITKKRYRLDHLLKEQPEEVLKRLTGPWRVEEENLHALVQ 131
Query: 127 HNIKCPE--------------CGGELGDVF---YFNLMFETYIGPYKDKK--AYLRPETA 167
++ PE GE GD YFN+MF+ GP + AYLRPETA
Sbjct: 132 AMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRGPRGGRGLLAYLRPETA 191
Query: 168 QGIFVNFKRLNAFARNKLPFGVFQIGKAYRNEISPRQGMIRLREFTQAEVEIFFNPNETE 227
+ + + KL FG+ Q + RNEI+PR + R+REF Q E+E F P E E
Sbjct: 192 RASSSTSRTVLDATSRKLGFGIAQSARPSRNEITPRNFIFRVREFEQMEIEYFVRPGEDE 251
Query: 228 HPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKKILLDIG 287
+ H Y +E +LK + L+ E V
Sbjct: 252 YWH----------RYWVEERLKWWQRMGLSRENLVP------------------------ 277
Query: 288 IPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMK 341
QQ PEE AHY+ T D +Y G E G+A RTD+DL H K
Sbjct: 278 --------YQQPPEELAHYAKATVDI-LYRFPHGLEELEGIANRTDFDLGSHTK 322
Score = 109 bits (270), Expect = 8e-23
Identities = 64/153 (41%), Positives = 95/153 (61%), Gaps = 15/153 (9%)
Query: 429 TGEKIIPHVLEPSFGIDRPFYLLLENSLTIDE----DGRIYLKIKKDMAPIEVAVLPLVA 484
TG+ +P+V+EPS G+DR LL + T +E + RI LK+K +API+VAV+PLV
Sbjct: 350 TGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVK 409
Query: 485 KEP-LTKIAYDLFRKLQKEGF-IVVYDEKDSIGKRYMRYDEIGTPYCVTI---------D 533
P +T+ A L +L G V+Y++ +IGK Y R+DE+GTP+ VT+ D
Sbjct: 410 NRPEITEYAKRLKARLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKD 469
Query: 534 NQTPIDGTVTIRDRDTREQIRVKLEDVPRKLKE 566
T + TVT+RDRDT EQIR+ ++++ L+E
Sbjct: 470 GTTRLKDTVTVRDRDTMEQIRLHVDELEGFLRE 502
>gb|AAB70033.1|AAB70033 (AC002534) similar to glycyl tRNA synthetase [Arabidopsis thaliana]
Length = 291
Score = 122 bits (303), Expect = 1e-26
Identities = 67/181 (37%), Positives = 101/181 (55%), Gaps = 9/181 (4%)
Query: 168 QGIFVNFKRLNAFARNKLPFGVFQIGK------AYRNEISPRQGMIRLREFTQAEVEIFF 221
+GIFV K L + K PF QIG+ AY +IS RQG++R+ EFT AE+E F
Sbjct: 88 KGIFV--KDLYYYNGRKFPFAAAQIGQPLEMSDAYYLQISHRQGLLRVCEFTLAEIEHFV 145
Query: 222 NPNETEHPHFDEVKHEKLRLYPIENQLKDLGMIELTAEEAVKKGYLMNTFFAYYLVMIKK 281
+P HP F +V + + ++P E Q+ +L E V KG + Y++ +
Sbjct: 146 DPGNKSHPKFSDVANFEFLMFPREEQMSGQSAKKLCLGEVVAKGTVNKETVGYFIARVYL 205
Query: 282 ILLDIGIPEDKIRFRQQLPEERAHYSADTWDAEVYSERFGWVECVGLAYRTDYDLSRHMK 341
L+ +G ++++RFRQ E A Y+AD DAE + +GW+ECVG+A R+ +DL H K
Sbjct: 206 FLVRLGTDKEQLRFRQHFANEMARYAADCLDAE-FESSYGWIECVGIADRSAFDLRAHSK 264
Query: 342 M 342
+
Sbjct: 265 L 265
>gb|AAC23791.1| (AC005154) glycyl-tRNA synthetase; similar to protein A55314
(PID:g1082407) [Homo sapiens]
Length = 245
Score = 83.1 bits (202), Expect = 8e-15
Identities = 44/99 (44%), Positives = 62/99 (62%), Gaps = 1/99 (1%)
Query: 11 LQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIEKKIREAFIR-EGFFEIETPDI 69
++D ++RR F +F IYGG G YD+GP+G +K I + R+ FI+ E EI+ +
Sbjct: 124 MEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTML 183
Query: 70 TPEQVFIASGHVEKFVDPIVECKKCGARFRADHLIEETL 108
TPE V SGHV+KF D +V+ K G FRADHL++ L
Sbjct: 184 TPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHL 222
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.142 0.412
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 215227470
Number of Sequences: 2977
Number of extensions: 9657064
Number of successful extensions: 28714
Number of sequences better than 1.0e-10: 41
Number of HSP's better than 0.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 28416
Number of HSP's gapped (non-prelim): 76
length of query: 571
length of database: 189,106,746
effective HSP length: 56
effective length of query: 515
effective length of database: 155,591,474
effective search space: 80129609110
effective search space used: 80129609110
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 167 (69.5 bits)