BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0390 (napA-2) DE:Na+/H+ antiporter (napA-2)
         (426 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abys...   826  0.0
pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus hori...   720  0.0
pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abys...   230  3e-59
pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus hori...   224  2e-57
gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus]            182  7e-45
pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus hori...   180  2e-44
gb|AAB40041.1| (U17283) putative spore germination apparatus pro...   180  4e-44
pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abys...   177  2e-43
pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp...   155  7e-37
sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A4211...   149  7e-35
emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus la...   129  8e-29
pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298...   126  4e-28
gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus] ...   120  3e-26
gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]        111  1e-23
pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus hori...   104  2e-21
dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabi...   103  3e-21
pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp...   100  3e-20
pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abys...   100  4e-20
pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC...    99  7e-20
pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii...    99  9e-20
pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thalian...    99  9e-20
pir||C82955 probable sodium/proton antiporter PA5529 [imported] ...    99  9e-20
gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum]     99  1e-19
pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis >...    98  2e-19
emb|CAB45049.1| (AL078635) putative integral membrane ion antipo...    98  2e-19
dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arab...    92  1e-17
gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana]    91  2e-17
dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans]     91  3e-17
gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter ...    90  3e-17
pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spir...    89  1e-16
pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana...    88  2e-16
gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]         86  9e-16
pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis >...    85  1e-15
pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298...    84  3e-15
gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40...    79  1e-13
pir||F69201 conserved hypothetical protein MTH760 - Methanobacte...    76  1e-12
gb|AAD30610.1|AC007153_2 (AC007153) similar to Na/H antiporter p...    74  3e-12
pir||T36239 probable integral membrane efflux protein - Streptom...    71  2e-11
pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum perni...    71  2e-11
gb|AAD32281.1|AC006533_5 (AC006533) putative Na+/H+ antiporter [...    70  4e-11
pir||F70591 probable kefB protein - Mycobacterium tuberculosis (...    70  5e-11
pir||A81330 probable glutathione-regulated potassium-efflux syst...    70  5e-11

>pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458000|emb|CAB49490.1| (AJ248284) Na+/H+
           antiporter (napA-2) [Pyrococcus abyssi]
           Length = 426
           
 Score =  826 bits (2110), Expect = 0.0
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 1   MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60
           MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT
Sbjct: 1   MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60

Query: 61  MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM 120
           MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM
Sbjct: 61  MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM 120

Query: 121 GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG 180
           GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG
Sbjct: 121 GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG 180

Query: 181 SGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW 240
           SGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW
Sbjct: 181 SGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW 240

Query: 241 FAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIK 300
           FAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIK
Sbjct: 241 FAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIK 300

Query: 301 LALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDL 360
           LALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDL
Sbjct: 301 LALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDL 360

Query: 361 MVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIE 420
           MVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIE
Sbjct: 361 MVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIE 420

Query: 421 KKKKAR 426
           KKKKAR
Sbjct: 421 KKKKAR 426


>pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
           >gi|3258023|dbj|BAA30706.1| (AP000006) 425aa long
           hypothetical Na(+)/H(+) antiporter [Pyrococcus
           horikoshii]
           Length = 425
           
 Score =  720 bits (1839), Expect = 0.0
 Identities = 353/423 (83%), Positives = 396/423 (93%)

Query: 4   ATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGS 63
           ATWILFTIG A+I+AKIGD+I+ERFELPGVLGEL+MGM LGNLVYFG++  +YLPITMGS
Sbjct: 3   ATWILFTIGTAIIIAKIGDSIVERFELPGVLGELLMGMALGNLVYFGLIKSEYLPITMGS 62

Query: 64  SEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYS 123
           SEVIDFLAKLGII LLFLGALDTD+E+LK+TG+TA +ST+MGVFVPL LGY+ALR MGY 
Sbjct: 63  SEVIDFLAKLGIILLLFLGALDTDIEKLKRTGVTAVVSTIMGVFVPLALGYYALRVMGYG 122

Query: 124 HREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGS 183
           +REAFAGGVLLTATSIGLTVR+MMDLG LRSEVGAASLSASV+DDFLGIALIIFAVGSGS
Sbjct: 123 YREAFAGGVLLTATSIGLTVRIMMDLGALRSEVGAASLSASVIDDFLGIALIIFAVGSGS 182

Query: 184 LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAA 243
           LL LS KII FFIITG+LGWY +D YI+FAE+LHVEKG+LG+ +G+MF+FAALAE WFAA
Sbjct: 183 LLELSAKIIVFFIITGVLGWYLVDHYIKFAEKLHVEKGVLGLVIGLMFIFAALAEDWFAA 242

Query: 244 AIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLAL 303
           AIEGSFM GLILSKLPEGKRIMEEVRSIGYG LIP+FF+HTGAMLNLTVF+N +A KLA 
Sbjct: 243 AIEGSFMAGLILSKLPEGKRIMEEVRSIGYGFLIPLFFVHTGAMLNLTVFKNIEAFKLAF 302

Query: 304 VLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVA 363
           VL+TIAV+GKV GRGFGAW+TAWGRGR FLFT++NF+MSLQMGIGSIPRTEVALVDLMVA
Sbjct: 303 VLTTIAVVGKVIGRGFGAWLTAWGRGRGFLFTKQNFRMSLQMGIGSIPRTEVALVDLMVA 362

Query: 364 IHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIEKKK 423
           IHGGAIS  +VPKFIAATLIFITVSVLITPPLLKWAF+EEVEAQ+ A++ESRKERIE+KK
Sbjct: 363 IHGGAISSGNVPKFIAATLIFITVSVLITPPLLKWAFKEEVEAQKMAKLESRKERIERKK 422

Query: 424 KAR 426
           KAR
Sbjct: 423 KAR 425


>pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abyssi  (strain
           Orsay) >gi|5459083|emb|CAB50569.1| (AJ248288) Na+/H+
           antiporter (napA-3) [Pyrococcus abyssi]
           Length = 380
           
 Score =  230 bits (580), Expect = 3e-59
 Identities = 140/402 (34%), Positives = 224/402 (54%), Gaps = 35/402 (8%)

Query: 7   ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEV 66
           +   + + L++AKI   +  R   P  LG+L+ G+++G            L +    SEV
Sbjct: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIG---------PSLLDVVEYGSEV 53

Query: 67  IDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHRE 126
              L++LG++ LLFL  L+TDVE+ K  GL+A I  +MGVFVP +LGY      GY   +
Sbjct: 54  -RLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLK 112

Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGS--- 183
           A   G +LTATS+GLT  ++MD+  LR++VG   L+A+++DD LGI ++   V   S   
Sbjct: 113 ALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGK 172

Query: 184 -----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAE 238
                +  + +++  FFI+  ++G   + + +  +ER+ + + +   A+ +M +FA LAE
Sbjct: 173 VEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAE 232

Query: 239 GWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADA 298
            +  A I G+++ GL++S     ++I +++ +IGY L IPIF +  G   ++ V  +A  
Sbjct: 233 KFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGV 292

Query: 299 IKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALV 358
              ALV S IAV+GK+ G GFGA           L  R     ++Q+GIG IPR EVAL+
Sbjct: 293 --FALVYSLIAVVGKIIGCGFGA-----------LVARFKPIEAIQVGIGMIPRMEVALI 339

Query: 359 DLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAF 400
              V +  G ++  D    +A  +  + ++ LITP LLKWAF
Sbjct: 340 IANVGLKEGILTRGD----LAVPVTMVVITTLITPFLLKWAF 377


>pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
           >gi|3256692|dbj|BAA29375.1| (AP000001) 380aa long
           hypothetical Na(+)/H(+) antiporter [Pyrococcus
           horikoshii]
           Length = 380
           
 Score =  224 bits (564), Expect = 2e-57
 Identities = 140/402 (34%), Positives = 222/402 (54%), Gaps = 35/402 (8%)

Query: 7   ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEV 66
           +L  + + L++AK+   ++ +   P  LG+LI G+++G            L I   S EV
Sbjct: 3   VLLELAIILVVAKLFGYLMVKLGFPAALGQLIGGIIIG---------PSLLNIVEYSQEV 53

Query: 67  IDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHRE 126
             FLA+LG+I LLFL  L+TDVE+ K  GL+A I   MGVFVP +LGY      GY    
Sbjct: 54  -RFLAELGVIILLFLAGLETDVEEFKHVGLSAFIVATMGVFVPFLLGYLIAIVYGYRSLA 112

Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGS--- 183
           A   G +LTATS+GLT  ++M++  LR++VG   L+A+++DD LGI ++   V   S   
Sbjct: 113 ALFLGGILTATSVGLTTSILMEMKKLRTKVGTTILAAAIVDDVLGIIILTILVAMSSRGR 172

Query: 184 -----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAE 238
                +  +  ++I FF++   +G   + + +  +E++ + + +   A+ +M LFA LAE
Sbjct: 173 VEIFDIEIILAEVIIFFLLGIFIGHPIVKEVLMLSEKITLPETVTTFAIVIMLLFAYLAE 232

Query: 239 GWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADA 298
            +  A I G+++ GL++S     K++ +++ +IGY L IPIF +  G   ++ V   A  
Sbjct: 233 KFQLAGITGAYLAGLLVSMSEGSKKVTDKMMTIGYSLFIPIFLVSIGIETDIKVLATAGV 292

Query: 299 IKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALV 358
              A+V S IA+IGK+ G GFGA +T +               +LQ+GIG IPR EVAL+
Sbjct: 293 --FAIVYSLIAIIGKIQGCGFGALVTKFKPAE-----------ALQVGIGMIPRMEVALI 339

Query: 359 DLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAF 400
              V +  G ++       +A  +  + V+ L+TP LLK AF
Sbjct: 340 IANVGLKEGILTRGT----LAIPVTMVVVTTLVTPFLLKLAF 377


>gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus]
           Length = 387
           
 Score =  182 bits (457), Expect = 7e-45
 Identities = 118/408 (28%), Positives = 209/408 (50%), Gaps = 32/408 (7%)

Query: 9   FTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVID 68
           F I + L+  K+   +  R   P VLG+LI+G+++G  V   I +          SE++ 
Sbjct: 7   FQIALILLSTKLAGDLSVRLGQPSVLGKLIVGIVIGPAVLGWIEN----------SELLT 56

Query: 69  FLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAF 128
            L+ +G+I L+F+  L+TD+E+L     ++    L G+ +P + GY +   MG     A 
Sbjct: 57  QLSNVGVILLMFMAGLETDLEELNANRNSSLAVALGGIILPFVGGYVSGLVMGMEQGNAV 116

Query: 129 AGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG-----SGS 183
             G+LL ATS+ ++V+ + DLG +++      L A+V DD L + L+ FA+        +
Sbjct: 117 FLGLLLCATSVSISVQTLRDLGKMKTRESTTMLGAAVFDDILVVILLAFAMSFLGTDDVN 176

Query: 184 LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAA 243
           L  + +K + FF    ++GW  +   +R+   L V + I+  A+ + F FA   E    A
Sbjct: 177 LTMVILKKVVFFASIILIGWKGVPAIMRWLSPLRVSESIVSAALIICFSFAYFGELLGIA 236

Query: 244 AIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLAL 303
            I G+F  G+ +S+      + ++V  I Y + +P+FF+  G  +N+T     + I   L
Sbjct: 237 GIIGAFAAGIAISQTNYKHEVEKKVEPIAYAMFVPVFFVSIG--MNITFDGIGNQIWFIL 294

Query: 304 VLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVA 363
            L+ IAV+ K+ G GFGA +T +           + K S  +G G + R EVAL+     
Sbjct: 295 ALTVIAVLTKLIGCGFGARMTGF-----------DAKSSAIIGAGMVSRGEVALIIAGTG 343

Query: 364 IHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKAR 411
           +  G ++ D    +  A +I + ++ +ITPP+LK+ F  + +A + ++
Sbjct: 344 LSSGLLAQD----YFTAIVIVVILTTMITPPMLKYTFGAKDKAMKASK 387


>pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
           >gi|3256522|dbj|BAA29205.1| (AP000001) 375aa long
           hypothetical Na(+)/H(+) antiporter [Pyrococcus
           horikoshii]
           Length = 375
           
 Score =  180 bits (453), Expect = 2e-44
 Identities = 121/398 (30%), Positives = 208/398 (51%), Gaps = 40/398 (10%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
           L  + + L +AK    I E+F  P VLG+++ G+L+G ++                +E+I
Sbjct: 4   LLLLAILLAVAKFSGWIFEKFNQPIVLGQILAGILMGLIIE--------------RNEII 49

Query: 68  DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127
              A LG++ LLFL  +++D+E+ KK G    +   +GV    I G F + Y  +    A
Sbjct: 50  IEFANLGVLMLLFLAGIESDLEEFKKVGKPGILVAGVGVLFAFIFG-FIVAYPFFDFGTA 108

Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGI---ALIIFAVGSGS- 183
              G ++T TS+ +TV+V+M+LG LR+  G   L+A+V+DD LGI    ++I  +  GS 
Sbjct: 109 MLYGAVMTPTSVSITVKVLMELGKLRTREGTTILAAAVIDDVLGILVLTIVISTLREGSV 168

Query: 184 ----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEG 239
               +L + +++  F  +   +G   ++   R   ++ + +     AV  + LFA LAE 
Sbjct: 169 HYDIILKILLEVAGFLAVFLYIGPVFMEDAFRRLSKIDLPEATTTFAVVFLVLFAYLAEH 228

Query: 240 WFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI 299
              A+I G++++GL + +    KRI + + ++GY + IP+FF+  G  ++      A   
Sbjct: 229 LNLASILGAYLIGLSIGQTSYKKRIEDHMNTLGYSIFIPLFFVDVGMRIDPRFLLQAKV- 287

Query: 300 KLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVD 359
             AL+ + IA++ KV G G GA++  +           ++K SL++GIG IPR  V L  
Sbjct: 288 -FALLYALIAMLSKVIGCGLGAYLANF-----------DWKSSLKIGIGMIPRLGVELAM 335

Query: 360 LMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLK 397
           +  A+  G    D +   +A T++F+T   L+TP LLK
Sbjct: 336 ITTAMASGIAGSDVLT--VAMTMVFLT--TLVTPLLLK 369


>gb|AAB40041.1| (U17283) putative spore germination apparatus protein [Bacillus
           megaterium] >gi|1589214|prf||2210362A grmA gene
           [Bacillus megaterium]
           Length = 386
           
 Score =  180 bits (451), Expect = 4e-44
 Identities = 120/403 (29%), Positives = 208/403 (50%), Gaps = 35/403 (8%)

Query: 9   FTIGVALIL--AKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEV 66
           F + +ALIL   KI   +  R   P VLG+L++G++LG  V  G +  D         + 
Sbjct: 3   FVLSLALILFATKIAGHLSVRLGQPSVLGKLLIGIILGPAV-LGWIHND---------QF 52

Query: 67  IDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHRE 126
           + + +++G++ L+FL  L+TD+EQLK+    A    ++G+ +P I G+      G     
Sbjct: 53  VHYFSEIGVLLLMFLAGLETDLEQLKRNWKAAFAVAVLGIILPFIGGFGVGELFGLGATY 112

Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGI---ALIIFAVGSGS 183
           +   GVLL ATS+ +TV+V+ D+  L S  G+  L A+V+DD L +   A++I  +G+G 
Sbjct: 113 SLFIGVLLCATSVSITVQVLKDMNRLNSREGSTILGAAVVDDVLVVVLLAIMISFLGTGE 172

Query: 184 LLGLSM---KIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW 240
            + L +   K + FFI   + GW  + K + +   L V + ++ + + + F +   A+  
Sbjct: 173 EVSLGLLVGKKLIFFIGAVLAGWLVVPKVLDWLTNLKVTEPVVSIGLAICFGYVYFADLM 232

Query: 241 FAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIK 300
             A I G+F  G+ +S+      I  +V  I Y + +P+FF+  G  LN++     D I 
Sbjct: 233 GMAGIIGAFAAGIAISQTSYRHTIESKVEPIAYAVFVPVFFVSIG--LNVSFEGVGDQIG 290

Query: 301 LALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDL 360
             L+LS IAVI K+ G   GA +T +           + + SL +G G + R EVAL+  
Sbjct: 291 FILLLSVIAVITKLVGGALGAKVTGF-----------STRSSLLIGSGMVSRGEVALIIA 339

Query: 361 MVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREE 403
              +    +    +P++  + +I I ++ L+ PPL+K+  + E
Sbjct: 340 ATGLQESLL----LPEYFTSAVIVIIITTLVAPPLIKYIIQSE 378


>pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abyssi  (strain
           Orsay) >gi|5457567|emb|CAB49058.1| (AJ248283) Na+/H+
           antiporter (napA-1) [Pyrococcus abyssi]
           Length = 375
           
 Score =  177 bits (445), Expect = 2e-43
 Identities = 118/398 (29%), Positives = 209/398 (51%), Gaps = 40/398 (10%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
           L  + + L +AK+   + ERF  P VLG++I G+++G L+                +E+I
Sbjct: 4   LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIE--------------RNEII 49

Query: 68  DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127
              A LG++ LLFL  L++D E+ K+ G  + +   +GV    + G F + Y  +    A
Sbjct: 50  VEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFG-FLIAYPFFDFGTA 108

Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGI---ALIIFAVGSGS- 183
              G ++T TS+ +TV+V+M+LG LR++ GA  L+A+V+DD LGI    ++I  +  GS 
Sbjct: 109 LLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSV 168

Query: 184 ----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEG 239
               ++ + +++  F  +   LG   ++   R   ++ + +     A+  + LFA LAE 
Sbjct: 169 HYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEH 228

Query: 240 WFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI 299
              A+I G++++GL + +    KRI   +  IGY + IP+FF+  G  ++       +A 
Sbjct: 229 LNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFL--FEAK 286

Query: 300 KLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVD 359
             A + +  A+I KV G G GA+++ +           +++ S+++GIG IPR  V L  
Sbjct: 287 TFAFLYAVFAMISKVIGCGLGAYLSKF-----------DWRTSIKIGIGMIPRLGVELAM 335

Query: 360 LMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLK 397
           +  A+  G    D +   +A T++F+T   LITP +L+
Sbjct: 336 ISTAMAAGVAGSDVLT--VAMTMVFLT--TLITPIMLR 369


>pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp.  (strain PCC
           6803) >gi|1001188|dbj|BAA10332.1| (D64001)
           NaH-antiporter protein [Synechocystis sp.]
           Length = 461
           
 Score =  155 bits (389), Expect = 7e-37
 Identities = 128/433 (29%), Positives = 214/433 (48%), Gaps = 59/433 (13%)

Query: 7   ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLG----NLVYF---GIVSKDYLPI 59
           +L ++ V    +K+G  +  R  LP VLGEL+ G+L+G     L+ F   G+  +D L I
Sbjct: 32  VLLSLVVIYFASKLGGEVCLRLNLPPVLGELVGGVLVGVSALKLLLFPEGGLAPEDSLVI 91

Query: 60  T--MGS---------------SEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATIST 102
              MGS               SEVI  +++LG+I LLF   L++++++L + G  A I  
Sbjct: 92  QLLMGSADLSPEAAQSVFSAQSEVISVISELGVIILLFEIGLESNLKELIRVGPQAAIVA 151

Query: 103 LMGVFVPLILGYFALRYM-GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASL 161
           ++GV  P  LG   L  + G +   A   G  LTATSIG+T +V+ ++  L S  G   +
Sbjct: 152 VVGVVTPFSLGTIGLMTIFGVAAIPAIFAGAALTATSIGITAKVLAEINRLSSNEGQIII 211

Query: 162 SASVMDDFLGIALIIFAVGS---------GSLLGLSMKIIAFFIITGILGWYSIDKYIRF 212
            A+V+DD LGI +++  VGS          +++ L +    F + + ++G      Y+  
Sbjct: 212 GAAVLDDILGI-IVLAVVGSLVKTGEIQISNIIYLILSATGFVVGSILIGRLLSPFYVSL 270

Query: 213 AERLHVEKGILGMAVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIG 272
             R+     +L +++ + F+ + +A+     AI GSF  GLIL++  + + + E++  + 
Sbjct: 271 VNRMKTRGQLLLVSICVAFVLSYIAQIVQLEAILGSFAAGLILAETEKREDLEEQILPLA 330

Query: 273 YGLLIPIFFIHTGA-----MLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWG 327
               +P+FF+  GA     +LN  V  N + + +A  L  +A++GKV   GF    T +G
Sbjct: 331 -DFFVPVFFVCVGAKTDVSVLNPAVPANREGLIIAAFLILVAIVGKVV-TGF----TLFG 384

Query: 328 RGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITV 387
           +              L +G+G IPR EV LV   V    GA+     P   AA ++ + V
Sbjct: 385 KSE---------LNKLAIGVGMIPRGEVGLVFAGVGAASGALD----PATDAAIIVMVIV 431

Query: 388 SVLITPPLLKWAF 400
           +  + PP L+  F
Sbjct: 432 TTFVAPPWLRAVF 444


>sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A42111 Na+/H+-exchanging
           protein NapA - Enterococcus hirae
           >gi|148316|gb|AAA24781.1| (M81961) NaH-antiporter
           protein [Enterococcus hirae]
           Length = 383
           
 Score =  149 bits (372), Expect = 7e-35
 Identities = 108/400 (27%), Positives = 205/400 (51%), Gaps = 36/400 (9%)

Query: 15  LILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFLAKLG 74
           L+   IG  I  RF +P V+G+L++G+LLG     G V  + L        V DF +++G
Sbjct: 11  LVATTIGSHISRRFGIPAVIGQLLVGVLLGQ-AGLGWVHPNIL--------VHDF-SEIG 60

Query: 75  IIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFAGGVLL 134
           +I L+FL  L++D+  LKK         L+G+  P+  G+        ++ EA   G++L
Sbjct: 61  VILLMFLAGLESDLSLLKKYFKPGMFVALLGILFPVFFGWLTGEAFQVANNEAIFFGIIL 120

Query: 135 TATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG-----SGSLLGLSM 189
            ATS+ ++V V+ +L V+ ++ G+  L ASV+DD L + ++ F++      S S L L +
Sbjct: 121 AATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLVLSFSLSFLTGKSTSNLPLPL 180

Query: 190 KIIA---FFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAAAIE 246
            ++    +F+   +L  +     +  AE+++    I+ M++ +    + LA+    +++ 
Sbjct: 181 LLLEQLFYFLFIFLLVKWIAPFLMSLAEKIYANSAIIIMSLVICLGMSYLADLIGLSSVI 240

Query: 247 GSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLALVLS 306
           G+F  G+ +S+      +   V ++GY + IP+FF+  G  ++ + F  ++ I   L+L+
Sbjct: 241 GAFFAGIAVSQTKVKHEVYNNVEALGYAVFIPVFFVSVGLEVDFSKF--SEQILFILILT 298

Query: 307 TIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVAIHG 366
            +A++ K+ G   GA            F+  +   +L +G G I R E+AL+ L +    
Sbjct: 299 LVAILTKLIGGYIGA-----------KFSSFSSNSALMVGAGMISRGEMALIILQIGQQS 347

Query: 367 GAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEA 406
             I       + +  +I + +S LI+P +LK+ F ++V A
Sbjct: 348 NLIE----NHYYSPLVIVVLLSTLISPLILKY-FTKKVYA 382


>emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus lactis]
           Length = 379
           
 Score =  129 bits (320), Expect = 8e-29
 Identities = 106/401 (26%), Positives = 196/401 (48%), Gaps = 34/401 (8%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
           +  + + LI + I      R ++P V+G++++G+L+   V  G+V          S  V+
Sbjct: 4   ILQLTIVLIASLIATLASRRLKIPAVIGQMLVGILIAPSV-LGLVH---------SGHVL 53

Query: 68  DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127
           + ++++G+I L+FL  L++D+  LKK    + +  + GV VPLI+        GY    +
Sbjct: 54  EVMSEIGVILLMFLAGLESDLTVLKKNFKASMLVAIGGVIVPLIVFGLVAFSFGYGMSTS 113

Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI-IFAV----GSG 182
           F  G++  ATS+ +TV V+ + G L +  G+  L A+V+DD L + ++ IF      GSG
Sbjct: 114 FFYGIVFAATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLILSIFTSFKNGGSG 173

Query: 183 SLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFA 242
           + L     +   F     +    I ++ +F ++L +      +A+ +    + LA+    
Sbjct: 174 THLFFQFLLELLFFAFLFVVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGM 233

Query: 243 AAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLA 302
           +A+ GSF  GL +S+     +I E   +IGY + IP+FF+     +      +   I   
Sbjct: 234 SAVIGSFFAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWI--I 291

Query: 303 LVLSTIAVIGKVAGRGFGAWITAWGRGR-DFLFTRENFKMSLQMGIGSIPRTEVALVDLM 361
           L+ + +A++ K        +I A+  G+ + L T E    S+ +G G I R E+AL+   
Sbjct: 292 LLFTLLAILTK--------FIPAYFVGKSNKLSTGE----SMLIGTGMISRGEMALIVAQ 339

Query: 362 VAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFRE 402
           + +   AI  D+V   +   +I  TV   + P L+K   ++
Sbjct: 340 IGL-TSAIITDEVYSELVIVIILATV---LAPFLIKLVLKK 376


>pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus
           >gi|2983453|gb|AAC07034.1| (AE000714) Na(+)/H(+)
           antiporter [Aquifex aeolicus]
           Length = 408
           
 Score =  126 bits (314), Expect = 4e-28
 Identities = 118/417 (28%), Positives = 192/417 (45%), Gaps = 54/417 (12%)

Query: 11  IGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFL 70
           + + L  AK+  +I  +  +P VLGE+  G++LG  V  G++     P+    SE I  L
Sbjct: 22  LAILLFSAKLFGSIFRKLGIPPVLGEVTAGVILGQSV-LGLI-----PL----SEAIKVL 71

Query: 71  AKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRY-MGYSHREAFA 129
           A+LG+I LLF   L+ D+  L + GL +T+  ++G  +P   G+    Y  G     +  
Sbjct: 72  AELGVILLLFEVGLEADINMLMRVGLWSTLVAIVGAALPFAGGFIVSYYFFGLDLVASLF 131

Query: 130 GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIF--------AVGS 181
            G  LTATSIG+TVRV+ DL   +       L A+V+DD +G+ ++          AV  
Sbjct: 132 MGGALTATSIGITVRVLTDLNKHKERFAQIVLGAAVLDDIMGVIILAALYEFSKTKAVHF 191

Query: 182 GSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWF 241
            + + L + I+ FF+I   +    + K +  A R   +  ++  ++  + L AA +   F
Sbjct: 192 DTTVNLIIHILMFFLIAPFVA-NVLAKLLSIAARKTQDMDLIPASIMALILLAAYSAHKF 250

Query: 242 AA-AIEGSFMMGLILSK---LPEGKRI---------MEEVRSIGYGLLIPIFFIHTGAML 288
            + +I GSF  GL LS+   +P    +         +EE  +    ++ PIFF+  G  L
Sbjct: 251 GSPSILGSFTAGLALSRRFVIPFAAMLRLDEKLLHKVEESITPLVWVMAPIFFVSVGLAL 310

Query: 289 NLTV--FRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMG 346
           NL    F + +    +  L  +A+IGKV   GF A                + K    +G
Sbjct: 311 NLKAIDFSSPEFWTFSSALIVVAIIGKVLA-GFVA--------------PGSLKEKASIG 355

Query: 347 IGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREE 403
              +PR EV L+         AI+  +     A  +  + V+ LI P +LK   +EE
Sbjct: 356 FSMLPRGEVGLIFAEFGRSFKAINEVE----YAVIVFVVAVTTLIAPIVLKLLLKEE 408


>gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus]
           >gi|7451786|pir||A69277 Na+/H+ antiporter (napA-1)
           homolog - Archaeoglobus fulgidus
           >gi|2650426|gb|AAB91016.1| (AE001091) Na+/H+ antiporter
           (napA-1) [Archaeoglobus fulgidus]
           Length = 377
           
 Score =  120 bits (298), Expect = 3e-26
 Identities = 100/402 (24%), Positives = 191/402 (46%), Gaps = 52/402 (12%)

Query: 10  TIGVALILAKIGDAIIERFELPGVLGELIMGMLLG----NLVYFGIVSKDYLPITMGSSE 65
           TI +  + A I   I ++  +P V+ E+++GM+ G    N++Y              +SE
Sbjct: 9   TIALISLTAFISPLIADKLRVPVVVLEIVLGMIFGVSFLNVIY--------------ASE 54

Query: 66  VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHR 125
            + FL+  G+IFL+FL  L+ D + + K+G    +     + + L +   AL  +   + 
Sbjct: 55  WLSFLSLFGLIFLMFLAGLEIDADVVLKSGHLKRVVAFFALSLALSVALTALMGLNLFY- 113

Query: 126 EAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGSL- 184
                 ++LT  ++G+ V V+ ++G+ + + G  ++  +++ DF  + L+     +G L 
Sbjct: 114 -----AIILTNVAVGVVVSVLREIGLEKEDFGQLNIVTALVSDFSTMFLLSIYFITGYLQ 168

Query: 185 LGLSMKIIAFFIITGILG----WYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW 240
           +  +  II  F+     G    W+  D   R+      E G+ G ++ +M LF  L+   
Sbjct: 169 VAFAFLIILVFLAAYRFGKLVIWHFPDFISRWFSDEPSEIGVRG-SLAIMILFVGLSSLL 227

Query: 241 FAAAIEGSFMMGLILS-KLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI 299
              AI G+F+ G++LS     GK++ +++  +G+G  IPIFFI TG+ LN+T        
Sbjct: 228 GVEAILGAFLAGVLLSITFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELNITQAGEGIGF 287

Query: 300 KLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVD 359
            L L+  ++AV                 +G   L    NF +   + +G +  T+++L  
Sbjct: 288 ILLLLAVSVAV-----------------KGIPSLIFASNFGLRRAISMGMLQSTKLSLTI 330

Query: 360 LMVAIHGGAISPDDVPKFIAATLI-FITVSVLITPPLLKWAF 400
             VAI    +S   + +F +  L+ F  +S L++P L ++ +
Sbjct: 331 AGVAI---GVSSGVITEFESTALVTFTIISCLLSPTLFRFLY 369


>gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]
           Length = 391
           
 Score =  111 bits (276), Expect = 1e-23
 Identities = 89/381 (23%), Positives = 182/381 (47%), Gaps = 27/381 (7%)

Query: 1   MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60
           M P    LF + + ++LA+I  ++++++ LP ++GEL+ GM++G      ++++      
Sbjct: 1   MNPIILALFDVSIFILLAEILSSLVQKYGLPKLIGELLAGMIIGPYALGSLLNQLLGFPL 60

Query: 61  MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM 120
           +G +  I+FLA+  +I L+F   L+  +  +K +G+   +    G  +P    Y+     
Sbjct: 61  IGINSYIEFLAEFSVILLIFASGLEHGIAPIKSSGILGFLGATFGALLPFFAAYY-FYIS 119

Query: 121 GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD-----FLGIALI 175
            +    A   G  + ATS+   V  +++ G L+ +     +S++  DD      L + + 
Sbjct: 120 SFGLDSALILGTAMGATSLA-AVASIIEEGKLKGKGINFMVSSAAADDVVDLLLLSVVIA 178

Query: 176 IFAVGSGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERL---HVEKGILGMAVGMMFL 232
           I    S S+  +S+KIIA  +I  ++   SI    +  +R+   ++E+  L +  G+  L
Sbjct: 179 ILQGESTSVTSISLKIIALVVIWVVILVVSIILIPKITDRISDKYIEEFPLAVLFGLTLL 238

Query: 233 FAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTV 292
             +L      + I  +F+ G+  +   +  +I +E+ S    +  P+FF++ GA +N   
Sbjct: 239 MVSLG----YSPIISAFVAGVAFANSVKNSKI-KEISSTLLSVFGPLFFVYIGAEVNFLT 293

Query: 293 FRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPR 352
             N + + L+L L+ IA I K        W+  +     +L    N K +  + +G +PR
Sbjct: 294 L-NLNTVILSLELTAIATIFK--------WLGIFPFALAYL---RNAKAANTVALGMVPR 341

Query: 353 TEVALVDLMVAIHGGAISPDD 373
            E  LV   + +   A++ ++
Sbjct: 342 GETGLVIASLGLSYNALNQEE 362


>pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
           >gi|3257347|dbj|BAA30030.1| (AP000004) 390aa long
           hypothetical Na(+)/H(+) antiporter [Pyrococcus
           horikoshii]
           Length = 390
           
 Score =  104 bits (257), Expect = 2e-21
 Identities = 96/414 (23%), Positives = 194/414 (46%), Gaps = 48/414 (11%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
           +F + + L++AK  + ++++  +  ++  ++ G++LG    FG      L I + +SE +
Sbjct: 4   IFDLSILLVVAKSLEWLLKKKGIHPIIAHILTGIILGP---FG------LSIVLPTSE-L 53

Query: 68  DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127
             L + G+I ++    L ++   + +  + A++  + GV    ILG+  + ++  S   A
Sbjct: 54  KVLGEFGLIMMMLYMGLTSNFSAISRNKVKASVVAMFGVAFSFILGFLTVYFLEKSLIAA 113

Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIAL--IIFAVGSGSLL 185
              G+ L  T+I +T  V++   V + ++ +  + A+  DD + + L  I+  +  G + 
Sbjct: 114 LFVGITLGNTAIEVTSGVLVRERV-KKDISSVLMGAAFADDIIAVYLIGILTGITQGGIS 172

Query: 186 GLSMKIIAFFIITGILGWYSIDKYI-----RFAERLHVEKGILGMAVGMMFLFAALAEGW 240
           GLS+  +   I+  ILG   + +++     RF   +          + + F  A +A+  
Sbjct: 173 GLSLVFLTIKIVIFILGVLMLSEFVFKRSTRFYNIIRDLHIFFTFTIVLTFTLAFIAQDI 232

Query: 241 FAAAIEGSFMMGLILSKLPEGK-----------RIMEEVRSIGYGLLIPIFFIHTGAMLN 289
               I G+++ GL +S+L E K            ++EE+  +     IP+FF++ G M N
Sbjct: 233 GLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELIEELEIVLVEFFIPLFFVYVGLMFN 292

Query: 290 LTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGS 349
             V     +I L L+L   AV+GK+ G G G  I              + + ++ +GIG 
Sbjct: 293 PNV--RDISILLILLLYASAVLGKLIGCGLGMKIFG-----------SSIRDAIIVGIGM 339

Query: 350 IPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFIT-VSVLITPPLLKWAFRE 402
             R  + L  L + +  G I      + I AT++ ++ ++ L TP L ++  R+
Sbjct: 340 GGRGSLELAILKLGLEKGLID-----EGIFATVVIVSMLTALSTPVLFRYTVRK 388


>dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabidopsis thaliana]
           Length = 810
           
 Score =  103 bits (255), Expect = 3e-21
 Identities = 85/331 (25%), Positives = 162/331 (48%), Gaps = 28/331 (8%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG--SSE 65
           +  I + ++L ++   ++     P V+ E+I G++LG  +     SK +L       S  
Sbjct: 35  ILQIVIVIVLTRVLAYLLRPLRQPRVIAEVIGGIMLGPSLLGR--SKAFLDAVFPKKSLT 92

Query: 66  VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGY---FALRYMGY 122
           V++ LA LG++F LFL  L+ D + L++TG  A    L G+ +P  LG    F L+    
Sbjct: 93  VLETLANLGLLFFLFLAGLEIDTKALRRTGKKALGIALAGITLPFALGIGSSFVLKATIS 152

Query: 123 SHREAFA----GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFA 178
               + A     GV L+ T+  +  R++ +L +L +E+G  ++SA+ ++D     L+  A
Sbjct: 153 KGVNSTAFLVFMGVALSITAFPVLARILAELKLLTTEIGRLAMSAAAVNDVAAWILLALA 212

Query: 179 VG-SGS-----------LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMA 226
           +  SGS           L G +  I A FII  I  W S     R  E   +E+  +   
Sbjct: 213 IALSGSNTSPLVSLWVFLSGCAFVIGASFIIPPIFRWIS----RRCHEGEPIEETYICAT 268

Query: 227 VGMMFLFAALAEGWFAAAIEGSFMMGLILSKL-PEGKRIMEEVRSIGYGLLIPIFFIHTG 285
           + ++ +   + +     ++ G+F++G+++ K  P    ++E+V  +  GL +P++F+ +G
Sbjct: 269 LAVVLVCGFITDAIGIHSMFGAFVVGVLIPKEGPFAGALVEKVEDLVSGLFLPLYFVASG 328

Query: 286 AMLNLTVFRNADAIKLALVLSTIAVIGKVAG 316
              N+   + A +  L ++++  A  GK+ G
Sbjct: 329 LKTNVATIQGAQSWGLLVLVTATACFGKILG 359


>pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp.  (strain PCC
           6803) >gi|1652066|dbj|BAA16991.1| (D90902) Na/H
           antiporter [Synechocystis sp.]
           Length = 410
           
 Score =  100 bits (247), Expect = 3e-20
 Identities = 99/412 (24%), Positives = 190/412 (46%), Gaps = 41/412 (9%)

Query: 7   ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVS----KDYLPITMG 62
           IL  I V + LA++   +  RF+ P V+GE+I G++LG  +  G++S    K + P T  
Sbjct: 9   ILANIIVIIGLARLIGLLFARFQQPPVIGEIIAGIMLGPSL-LGLLSPALEKSFFPAT-- 65

Query: 63  SSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILG----YFALR 118
           +   +  L+++G+IF +FL  L+ + + L++    A +++ + +F P +LG    +F L 
Sbjct: 66  TQPFLYLLSEIGLIFYMFLVGLELNPQYLRQKLKVAILTSNVSIFFPFVLGIVLSFFVLY 125

Query: 119 YMGYSHREAFAG-----GVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIA 173
            +   ++ +F       G  ++ T+  +  R++ D G+ ++ +G   L+ + +DD     
Sbjct: 126 SLNQPNKTSFIPFALFIGAAMSITAFPVLARILKDTGLDKTPLGTLGLTCASVDDISAWC 185

Query: 174 LIIFAVG---SGSLLG---LSMKIIAFFIITGILGWYSIDKYI--RFAERLHVEKGILGM 225
           L+  A+    + ++ G     + II + +    LG     KYI   + ++ ++ +G+L  
Sbjct: 186 LLAIAIAVTRTDNIFGAFPTLLGIIVYTVFMVTLG-RKFFKYILRNYGQKNYLSQGLLTF 244

Query: 226 AVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLPE-GKRIMEEVRSIGYGLLIPIFFIHT 284
              M+ L A L E      I G F++G IL K       +  +        L+PIFF ++
Sbjct: 245 IYIMVILSAMLTEWIGIDVIFGGFILGAILPKNTNLSTELATKTEDFVSTFLLPIFFAYS 304

Query: 285 GAMLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQ 344
           G   +L +            +  + V   +AG+  G ++T    G +    ++  K    
Sbjct: 305 GLSTDLGLLNK----PYLWAVCALVVAAAIAGKYCGVYVTTRALGVE----KQEAK---A 353

Query: 345 MGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLL 396
           +G     R    L+ L V +  G ISP     F+    I   ++ +IT PL+
Sbjct: 354 LGWLMNTRGLTELIILNVGLKLGVISPVIFTMFV----IMAIITTIITSPLV 401


>pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458640|emb|CAB50128.1| (AJ248286) Na+/H+
           antiporter (napA-4) [Pyrococcus abyssi]
           Length = 390
           
 Score =  100 bits (246), Expect = 4e-20
 Identities = 92/409 (22%), Positives = 191/409 (46%), Gaps = 53/409 (12%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
           +F + + L++AK  + ++++  +  ++  ++ G++LG    FG+         +  SE +
Sbjct: 4   IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGP---FGLA-------IVKPSEEL 53

Query: 68  DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127
             L + G+I ++    L ++   + +  + ATI   +GV    ILG+  + ++  +   A
Sbjct: 54  KVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAA 113

Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI--IFAVGSGS-- 183
              G+ L  T+I +T  V++   V + E+ +  + A+  DD + + LI  +  +  GS  
Sbjct: 114 LFVGITLGNTAIEVTSGVLVRERV-KKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFS 172

Query: 184 ---LLGLSMKIIAFFIITGILGWYSIDKYIRF---AERLHVEKGILGMAVGMMFLFAALA 237
              ++ L++KI+ F + T ++  +   +  RF    + LHV        + + F+ A LA
Sbjct: 173 LYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHV---FFTFTIILTFMLAFLA 229

Query: 238 EGWFAAAIEGSFMMGLILSKLPEGK-----------RIMEEVRSIGYGLLIPIFFIHTGA 286
           E      I G+++ GL +S+L E K            ++ E+  +     IP+FFI+ G 
Sbjct: 230 EDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGL 289

Query: 287 MLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMG 346
           M    V R    + +AL L   A++GK+ G G G            L    + + ++ +G
Sbjct: 290 MFQPNV-REISVLMIAL-LYLAAILGKLIGCGLG-----------MLLFGSSLRDAIIVG 336

Query: 347 IGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPL 395
           +G   R  + L  L + +  G I+     + + AT++ +++   ++ P+
Sbjct: 337 VGMGGRGSLELAILKLGLEKGLIN-----ESLFATIVIVSMLTALSTPI 380


>pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1001647|dbj|BAA10378.1| (D64002) Na(+)/H(+)
           antiporter [Synechocystis sp.]
           Length = 698
           
 Score = 99.5 bits (244), Expect = 7e-20
 Identities = 94/406 (23%), Positives = 181/406 (44%), Gaps = 31/406 (7%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
           L    + L++  I   I ER +LPG++G L  G++LG     G++++D        SE I
Sbjct: 13  LIDFTILLLVTLILPPIFERLKLPGLVGLLFAGIVLGKSG-LGVLNED--------SESI 63

Query: 68  DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127
                +G I+L+F+  L+ D+   ++T   + +   +   VPL+ G       GYS   +
Sbjct: 64  KLFTDIGKIYLMFVAGLEIDMVDFRRTRNRSLLYGSLTFAVPLLTGLAVGLTFGYSFNAS 123

Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAV----GSGS 183
              G L  + ++ L   ++  LG++R++    ++ A++  D   + ++   +    GS S
Sbjct: 124 VLLGSLFASHTL-LGYPIVQRLGIVRNQAVMVTIGATIFTDIAALLVLAICISIHSGSFS 182

Query: 184 LLGLSMKIIAFFIITGIL----GWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEG 239
             GL ++++A  + + ++     W   + + R  +    +   + +AV   FL +  +E 
Sbjct: 183 PAGLVVQLVAIAVYSALVLIGFDWAGREYFRRTGDEQSNQFLFVLLAV---FLASVGSEL 239

Query: 240 WFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI 299
                I G+F+ GL ++ +     + E+V  +G  L IP FFI  G +L+L  F      
Sbjct: 240 INVDKIVGAFLAGLAVNDVLGNSPVKEKVEFLGTTLFIPFFFIGIGLLLDLPAFLVTLTT 299

Query: 300 KLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVD 359
              LV++   V+G +  +G  A +  W  G  ++         L M   SIP+    L  
Sbjct: 300 LFPLVVA--IVVGLILSKGVAAILAQWKLGYTWV-------EGLTMWSLSIPQVAATLAA 350

Query: 360 LMVAIHGGAISPDD-VPKFIAATLIFITVSVLITPPLLKWAFREEV 404
            +        + D  V + +  T+I + +   I  PL+   F  ++
Sbjct: 351 AVAGYQAVNAAGDRLVSETVLNTIIVLMLITSIVGPLMTAKFAPKI 396


>pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii
           >gi|1591911|gb|AAB99281.1| (U67568) NA(+)/H(+)
           antiporter (napA) [Methanococcus jannaschii]
           Length = 388
           
 Score = 99.1 bits (243), Expect = 9e-20
 Identities = 95/408 (23%), Positives = 187/408 (45%), Gaps = 38/408 (9%)

Query: 1   MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60
           ME   ++ F I   L +  I   ++++F +P +   +I G+++G    +G+   + L + 
Sbjct: 1   MESYYYVFFII---LSIIFIVPNLLKKFNIPAITSIMIAGIIIGP---YGL---NILQV- 50

Query: 61  MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM 120
               E +  LA  G I L+FL  L+ D E LK+    + I +L  + +P + GY   +Y+
Sbjct: 51  ---DETLKILADFGAIMLMFLAGLEVDNETLKQEFKNSLILSLFSLLIPGVGGYLIGQYL 107

Query: 121 GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIAL--IIFA 178
           G     +    V+  + S+ +   ++ +L ++++ +G   LSA+++ D   + L  ++  
Sbjct: 108 GLGFIGSLLYAVIFASHSVAIVYAILEELKMVKTRLGTIILSATIIVDLFTLLLLSVVIK 167

Query: 179 VG-SGSLLGLSMKIIAFFIITGILGWYSIDKYI-RFAERLHVEKGILGMAVGMMFLFAAL 236
           +G  G  +G  +     +I   +L   S+ K I    E+LH ++  +   + ++F+   +
Sbjct: 168 LGIGGENVGTFLLETVLYIGVLLLAIPSLSKNILGVFEKLHAQR--IHYVLFIIFIAIIV 225

Query: 237 AEGWFAAAIEGSFMMGL----ILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTV 292
            E      I G+F+ G+     L+K    + + + + +IGYG  IPIFF+  G   N+ V
Sbjct: 226 GEVIGIHPIVGAFICGVAVSEALTKEEHDELLNKNLNAIGYGFFIPIFFLVLGMETNIRV 285

Query: 293 FRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPR 352
             N   ++L L+    AV  K         I  + R ++ +            G+ ++P+
Sbjct: 286 IFNLSNLELLLITLISAVALKFISGFIALRILGFDRIKNTI-----------GGLLTVPK 334

Query: 353 TEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAF 400
              +LV   +    G I  +     +A ++I  T    ITP ++K  F
Sbjct: 335 ISASLVAASIGRELGLIGNEIFVTIVALSVITAT----ITPIVVKHIF 378


>pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thaliana
           >gi|4454039|emb|CAA23036.1| (AL035394) putative
           Na+/H+-exchanging protein [Arabidopsis thaliana]
           >gi|7269218|emb|CAB79325.1| (AL161559) putative
           Na+/H+-exchanging protein [Arabidopsis thaliana]
           Length = 820
           
 Score = 99.1 bits (243), Expect = 9e-20
 Identities = 89/332 (26%), Positives = 157/332 (46%), Gaps = 28/332 (8%)

Query: 7   ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEV 66
           ++  I + L+L ++   ++     P V+ E++ G+LLG                  S  V
Sbjct: 33  LILQICIVLLLTRLLAFLLRPLRQPRVIAEIVGGILLGPSALGKSTKFINTVFPPKSLTV 92

Query: 67  IDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGY---FALRYM--- 120
           +D LA LG+IF LFL  L+ D + LK+TG  A    L G+ +P +LG    FALR     
Sbjct: 93  LDTLANLGLIFFLFLVGLELDPKSLKRTGKRALSIALAGITLPFVLGIGTSFALRSSIAD 152

Query: 121 GYSHREAFA-GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAV 179
           G S        GV L+ T+  +  R++ ++ +L +++G  +LSA+ ++D     L+  AV
Sbjct: 153 GASKAPFLVFMGVALSITAFPVLARILAEIKLLTTDIGKIALSAAAVNDVAAWILLALAV 212

Query: 180 ---GSGS---------LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAV 227
              G GS         L G    +   F++    G   I K  R  E   V +  +   +
Sbjct: 213 ALSGEGSSPLTSLWVFLSGCGFVLFCIFVVQP--GIKLIAK--RCPEGEPVNELYVCCTL 268

Query: 228 GMMFLFAALAEGWFAAAIEGSFMMGLILSKLPEG---KRIMEEVRSIGYGLLIPIFFIHT 284
           G++   + + +     A+ G+F++G+I  K  EG     ++E+V  +  GL +P++F+ +
Sbjct: 269 GIVLAASFVTDFIGIHALFGAFVIGVIFPK--EGNFANALVEKVEDLVSGLFLPLYFVSS 326

Query: 285 GAMLNLTVFRNADAIKLALVLSTIAVIGKVAG 316
           G   N+   + A +  L +++   A  GK+ G
Sbjct: 327 GLKTNVATIQGAQSWGLLVLVIFNACFGKIIG 358


>pir||C82955 probable sodium/proton antiporter PA5529 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9951867|gb|AAG08914.1|AE004965_6 (AE004965) probable
           sodium/proton antiporter [Pseudomonas aeruginosa]
           Length = 585
           
 Score = 99.1 bits (243), Expect = 9e-20
 Identities = 87/401 (21%), Positives = 186/401 (45%), Gaps = 42/401 (10%)

Query: 11  IGVALILAKIGDAIIERFELPGVLGELIMGMLLG-NLVYFGIVSKDYLPITMGSSEVIDF 69
           + V +++A +   +  R   P VLG ++ G ++G +   FG++  +         + I  
Sbjct: 10  LAVIMLVAGVVTILFHRLRQPVVLGYIVAGFIIGPHTPPFGLIHDE---------DTIKT 60

Query: 70  LAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFA 129
           LA+LG+IFL+F   L+  + +L + G TA I+  + + + + +G+   R+  +S  ++  
Sbjct: 61  LAELGVIFLMFCLGLEFSLRKLFQVGATAFIAAFLEIVLMIWIGFEIGRFFEWSTMDSLF 120

Query: 130 GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIF--------AVGS 181
            G +L  +S  + V+ + DL +             +++D LGI +I          +V +
Sbjct: 121 LGAILAISSTTIIVKALGDLKMKNERFAQLIFGVLIVEDILGIGIIALLSGIAVSGSVET 180

Query: 182 GSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWF 241
           G +     K+  F I+  ++G   + + + +  +    + +L   +G+ F F  L     
Sbjct: 181 GEVFSTVGKLSLFMIVALVVGILLVPRLLAYVAKFESNEMLLVTVLGLCFGFCLLVVKLE 240

Query: 242 AAAIEGSFMMGLILS---KLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADA 298
            + + G+F++G I++   +L + +R++E VR     +   IFF+  G +++  +     A
Sbjct: 241 YSMVLGAFLIGAIMAESRQLVQIERLIEPVRD----MFSAIFFVAIGLLIDPKILVEY-A 295

Query: 299 IKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALV 358
             +AL+ +   V+GK+   G GA+I              + + SL++G+G     E + +
Sbjct: 296 WPIALI-TVAVVLGKMFSCGMGAFIAG-----------NDGRTSLRVGMGLSQIGEFSFI 343

Query: 359 DLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWA 399
              + +     S    P  +A +     ++ L+TP L++ A
Sbjct: 344 IAALGMTLKVTSDFLYPVAVAVS----AITTLLTPYLIRAA 380


>gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum]
           Length = 713
           
 Score = 98.7 bits (242), Expect = 1e-19
 Identities = 99/432 (22%), Positives = 192/432 (43%), Gaps = 35/432 (8%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITM--GSSE 65
           L T+ + L+ A+    +  R   P VLGEL  G++LG  V   +    +  +        
Sbjct: 13  LVTLALILVTARASGELARRLRQPEVLGELFGGVVLGPSVVGALAPGFHRALFQEPAVGV 72

Query: 66  VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILG-YFALRYMGYSH 124
           V+  ++ +G + LL +  ++ DV  L+K      +S L  +  PL  G  F+   +    
Sbjct: 73  VLSGISWIGALLLLLMAGIEVDVGILRKEARPGALSALGAIAPPLAAGAAFSALVLDRPL 132

Query: 125 REAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD---FLGIALIIFAVGS 181
                 G++L+ T++ +  +V+++   +R      +L+A V+ +   ++ +A+   + G+
Sbjct: 133 PSGLFLGIVLSVTAVSVIAKVLIERESMRRSYAQVTLAAGVVSEVAAWVLVAMTSSSYGA 192

Query: 182 GSLLGLSMKII---AFFIITGILGWYSIDKYIRF-AERLHVEKGILGMAVGMMFLFAALA 237
              L ++   +    F +   ++G       +R+ A+   V KG + + + + FL AAL 
Sbjct: 193 SPALAVARSALLASGFLLFMVLVGRRLTHLAMRWVADATRVSKGQVSLVLVLTFLAAALT 252

Query: 238 EGWFAAAIEGSFMMGLILSKLPEGKR-IMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNA 296
           +      + G+F +G++L+  P   R +++ V+++  GL  P+FF+  G  ++++  R  
Sbjct: 253 QRLGLHPLLGAFALGVLLNSAPRTNRPLLDGVQTLVAGLFAPVFFVLAGMRVDVSQLRTP 312

Query: 297 DAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVA 356
            A     +L   A   KV     GA +    RG +         + L M  G+       
Sbjct: 313 AAWGTVALLLATATAAKVVPAALGARLGGL-RGSEAALV----AVGLNMKGGT------- 360

Query: 357 LVDLMVAIHG---GAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIE 413
             DL+VAI G   G +S +    +    L+ +T S    P LL W  +     Q ++   
Sbjct: 361 --DLIVAIVGVELGLLSNEAYTMYAVVALVTVTAS----PALLIWLEKRAPPTQEES--- 411

Query: 414 SRKERIEKKKKA 425
           +R ER E  ++A
Sbjct: 412 ARLEREEAARRA 423


>pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis
           >gi|2633518|emb|CAB13021.1| (Z99110) similar to Na+/H+
           antiporter [Bacillus subtilis]
           Length = 614
           
 Score = 98.3 bits (241), Expect = 2e-19
 Identities = 80/325 (24%), Positives = 157/325 (47%), Gaps = 35/325 (10%)

Query: 13  VALILAKIGDAIIERFEL--PGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFL 70
           V LI+A +   ++ RF+L  P V+ E+IMG+++G         K  L + +     +  L
Sbjct: 11  VVLIVAFLTPILLHRFKLSIPVVVAEIIMGLIIG---------KSGLNLVVEGDTWLQTL 61

Query: 71  AKLGIIFLLFLGALDTDVEQLKK--------------TGLTATISTLMGVFVPLILGYFA 116
           + LG IFL+FL  L+ D    +K                  A     +G+F+  +L  + 
Sbjct: 62  SMLGFIFLMFLSGLEIDFSSFEKGKKKQFLPNGKEAPNTFAAASVIFVGIFILSLLLSYG 121

Query: 117 LRYMGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI- 175
               G+  + AF   ++++  S+G+ V  + +  ++ S +G   L  +V+ D   + L+ 
Sbjct: 122 FVLAGFI-QNAFLMTLIISTISLGVVVPTLKEERIMNSNIGQIILLVAVIADLATMILLA 180

Query: 176 IFAVGSGSLLGLSMKIIAFFIITGILGWYS-IDKYIRFAERLHVEKGILGMAVGMMF--- 231
           +F+   G   G    ++  F    +L ++  + K+  F + +   KG + +    +F   
Sbjct: 181 VFSSLYGEDSGNMWLLMILFAAGVVLYFFGRVFKHRSFVQSM--SKGTIQIGTRAIFTLI 238

Query: 232 -LFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNL 290
            +  AL+E   A  I G+F+ G+++S L   K +++++ S GYG LIPIFF+  G  L++
Sbjct: 239 IVLVALSESLGAENILGAFLAGVLVSLLSPNKELVQQLDSFGYGFLIPIFFVMVGVKLDI 298

Query: 291 -TVFRNADAIKLALVLSTIAVIGKV 314
            T+F++   + +  +L    ++ K+
Sbjct: 299 WTLFQDKTILIMIPLLLLALLVSKI 323


>emb|CAB45049.1| (AL078635) putative integral membrane ion antiporter [Amycolatopsis
           orientalis]
           Length = 409
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 83/328 (25%), Positives = 152/328 (46%), Gaps = 18/328 (5%)

Query: 6   WILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSE 65
           ++L  + V ++LA++  A+  R + P V+GEL+ G+LLG  ++    +    P  +    
Sbjct: 8   FLLLDLAVIVVLARLLGAVARRLDQPPVIGELLAGILLGPTLFGEGFAAALFPTDV--RP 65

Query: 66  VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYS-- 123
            +  LA +G+   +F+  L+ +   L+  G  A   ++  + +P  LG     Y+  +  
Sbjct: 66  FLAALANVGVAMFMFMVGLELEQTLLRGRGKLALTVSVSSIVLPFTLGVGLAFYLAMNRP 125

Query: 124 --HREAFA--GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI-IFA 178
             HR  F    G  ++ T+  +  R++ D G+LR+ +G  +L+ + + D L   L+ +  
Sbjct: 126 VEHRLGFLLFIGAAMSVTAFPVLARILQDRGMLRTMLGGLALTCAAIGDVLAWCLLAVVV 185

Query: 179 VGSGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAE 238
           + SG   G    +I    I   L  + +   +R      V  G L   +    +  A+ E
Sbjct: 186 IVSGGASGTEQWLIVLGPIYVALMLWVVRPLLRKLFTAGV-TGALPTVLAGALISGAVTE 244

Query: 239 GWFAAAIEGSFMMGLILSKLPEG-----KRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVF 293
                 I G+F+ G+I+ +  EG      RI++ V      LL+P+FFI +G  +NL+  
Sbjct: 245 LIGLHFIFGAFLFGVIVPR--EGTDTLRHRIIDRVEEFNSALLLPVFFIVSGLKVNLSTL 302

Query: 294 RNADAIKLALVLSTIAVIGKVAGRGFGA 321
                ++  LVL  +A+ GK  G   GA
Sbjct: 303 SATGLVEFGLVL-LVAIAGKFGGAFVGA 329


>dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arabidopsis thaliana]
           Length = 800
           
 Score = 91.7 bits (224), Expect = 1e-17
 Identities = 78/328 (23%), Positives = 164/328 (49%), Gaps = 20/328 (6%)

Query: 7   ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG--SS 64
           I+  I + ++  ++    ++  + P V+ E+I G+LLG        SK YL       S 
Sbjct: 35  IILQIVLVVVFTRLLAYFLKPLKQPRVIAEIIGGILLGPSALGR--SKAYLDTIFPKKSL 92

Query: 65  EVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSH 124
            V+D LA +G++F LFL  L+ D   +KKTG  + +  + G+ +P I+G      +  + 
Sbjct: 93  TVLDTLANIGLLFFLFLVGLELDFAAIKKTGKKSLLIAIAGISLPFIVGVGTSFVLSATI 152

Query: 125 REAFAG-------GVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD---FLGIAL 174
            +           GV L+ T+  +  R++ +L +L +++G  ++SA+ ++D   ++ +AL
Sbjct: 153 SKGVDQLPFIVFMGVALSITAFPVLARILAELKLLTTDIGRMAMSAAGVNDVAAWILLAL 212

Query: 175 IIFAVGSGSLLGLSMKII---AFFIITGILGWYSIDKYI--RFAERLHVEKGILGMAVGM 229
            I   G G+   +S+ ++     F+I  ++    +  Y+  R  E   V++  + + + +
Sbjct: 213 AIALSGDGTSPLVSVWVLLCGTGFVIFAVVAIKPLLAYMARRCPEGEPVKELYVCVTLTV 272

Query: 230 MFLFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIM-EEVRSIGYGLLIPIFFIHTGAML 288
           +   + + +     A+ G+F++G++  K     RI+ E++  +  GLL+P++F  +G   
Sbjct: 273 VLAASFVTDTIGIHALFGAFVVGIVAPKEGPFCRILTEKIEDLVSGLLLPLYFAASGLKT 332

Query: 289 NLTVFRNADAIKLALVLSTIAVIGKVAG 316
           ++T  R A +  L +++      GK+ G
Sbjct: 333 DVTTIRGAQSWGLLVLVILTTCFGKIVG 360


>gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana]
           Length = 868
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 82/303 (27%), Positives = 142/303 (46%), Gaps = 35/303 (11%)

Query: 40  GMLLGNLVYFGIVSKDYLPITMGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTAT 99
           G+LLG      I S         S  V+D LA LG++  LFL  L+ D+  L++TG  A 
Sbjct: 132 GILLGPSALGRITSYKNSIFPARSLTVLDTLANLGLLLFLFLVGLEIDLTSLRRTGKKAI 191

Query: 100 ISTLMGVFVPLILGYFALRYMGYSHREAFAGG-------------VLLTATSIGLTVRVM 146
                G+ +P  +G        ++  EA + G             V L+ T+ G+  R++
Sbjct: 192 SIAAAGMLLPFGMGIVT----SFAFPEASSSGDNSKVLPFIIFMGVALSITAFGVLARIL 247

Query: 147 MDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG-SGSL------LGLSMKIIAFFIITG 199
            +L +L +++G  S++A+ ++D     L+  AV  SG        L + +  IAF I   
Sbjct: 248 AELKLLTTDLGRISMNAAAINDVAAWVLLALAVSLSGDRNSPLVPLWVLLSGIAFVIACF 307

Query: 200 ILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAAAIE-----GSFMMGLI 254
           ++    + +  +F  R   E   +G     + L A L  G+   AI      G+F+MG++
Sbjct: 308 LI----VPRIFKFISRRCPEGEPIGEMYVCVALCAVLLAGFATDAIGIHAIFGAFVMGVL 363

Query: 255 LSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI-KLALVLSTIAVIGK 313
             K      I+E++  +  GLL+P++F+ +G   ++T  +   +  +LALV+ T A  GK
Sbjct: 364 FPKGHFSDAIVEKIEDLVMGLLLPLYFVMSGLKTDITTIQGVKSWGRLALVIVT-ACFGK 422

Query: 314 VAG 316
           + G
Sbjct: 423 IVG 425


>dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans]
           Length = 686
           
 Score = 90.9 bits (222), Expect = 3e-17
 Identities = 88/421 (20%), Positives = 194/421 (45%), Gaps = 46/421 (10%)

Query: 3   PATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG 62
           P T  +    +A+++  +   ++ R  +PG++G ++ G+++G    F ++ +D   + +G
Sbjct: 5   PITDPVLIFAIAMVVFFVAPLLMSRLRIPGIIGLILAGVVIGPNG-FALLDRDPTIVLLG 63

Query: 63  SSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGY 122
           +         +G+++++F+  L+ D+E  KK    + +   +   +P + G      +G+
Sbjct: 64  T---------VGLLYIIFIAGLEIDLEGFKKYRNRSVLFGTLSFTIPFLFGLVFTFILGF 114

Query: 123 SHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSG 182
           S   A     +L + ++ L   +   LG+ +      ++  ++M D L  AL++ A+ +G
Sbjct: 115 STPAAILLASILGSHTL-LAYPIASRLGISKDRGVTTAVGGTIMTDTL--ALLVLAIVAG 171

Query: 183 SLLG---------LSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLF 233
           S+ G         +++ ++ +  IT IL    I    +   R    +G L     M  LF
Sbjct: 172 SMQGELNSTFWFTIAVSLVLYVAITLIL----IPILAKSFFRTMSSEGALEFIFVMSILF 227

Query: 234 AALAEGWFAAAIE---GSFMMGLILSK-LPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLN 289
              A G   A +E   G+F+ GL L++ + E   +M  ++ +G  L IP F +  G +++
Sbjct: 228 VT-AYGATLAGLEPIIGAFLAGLALNRFILEHSPLMNRIKFVGNALFIPFFLLSVGMLMD 286

Query: 290 LTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGS 349
           + V     +   A +L+ + VI    G+   A+I+    G+ + ++ +  K+   +   S
Sbjct: 287 IRVLLGDPS---AWLLAALVVIFVQLGKFLAAFIS----GKLYNYSMDQIKLMFGL---S 336

Query: 350 IPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLL-KWAFREEVEAQR 408
           +P+    L   +V    G          + A ++ I V+ ++ P ++ K+A +  +E + 
Sbjct: 337 VPQAAATLAATLVGFDLGLFD----SAVVNAVIVMILVTCMVGPYVVEKYARKLALEEEL 392

Query: 409 K 409
           K
Sbjct: 393 K 393


>gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter [Arabidopsis thaliana]
           Length = 821
           
 Score = 90.5 bits (221), Expect = 3e-17
 Identities = 88/390 (22%), Positives = 169/390 (42%), Gaps = 40/390 (10%)

Query: 24  IIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFLAKLGIIFLLFLGA 83
           I++ F  P V+ E++ G++LG  V        +      S  V++ +A +G+++ LFL  
Sbjct: 57  ILKPFRQPRVISEILGGIVLGPSVLGRSTKFAHTIFPQRSVMVLETMANVGLLYFLFLVG 116

Query: 84  LDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFAG------GVLLTAT 137
           ++ D+  ++KTG  A    + G+ +P ++G      M  S      G      GV L+ T
Sbjct: 117 VEMDIMVVRKTGKRALTIAIGGMVLPFLIGAAFSFSMHRSEDHLGQGTYILFLGVALSVT 176

Query: 138 SIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSG-----SLLGLSMKI- 191
           +  +  R++ +L ++ +E+G  S+SA++++D     L+  A+        S   L + I 
Sbjct: 177 AFPVLARILAELKLINTEIGRISMSAALVNDMFAWILLALAIALAESDKTSFASLWVMIS 236

Query: 192 ------IAFFIITGILGWY--SIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAA 243
                 +  F++   + W      +   F+E  H+   + G+ +      A      F  
Sbjct: 237 SAVFIAVCVFVVRPGIAWIIRKTPEGENFSE-FHICLILTGVMISGFITDAIGTHSVF-- 293

Query: 244 AIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLAL 303
              G+F+ GL++   P G  ++E++     GLL+P+FF  +G   N+   +         
Sbjct: 294 ---GAFVFGLVIPNGPLGLTLIEKLEDFVSGLLLPLFFAISGLKTNIAAIQGPATWLTLF 350

Query: 304 VLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVA 363
           ++  +A  GKV     G  I A+  G   +  RE   + L +           LV+++V 
Sbjct: 351 LVIFLACAGKV----IGTVIVAFFHG---MPVREGITLGLLL-------NTKGLVEMIVL 396

Query: 364 IHGGAISPDDVPKFIAATLIFITVSVLITP 393
             G      D   F    L+ + ++ +ITP
Sbjct: 397 NVGKDQKVLDDETFATMVLVALVMTGVITP 426


>pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spirochete
           >gi|2688368|gb|AAC66821.1| (AE001150) Na+/H+ antiporter
           (napA) [Borrelia burgdorferi]
           Length = 701
           
 Score = 88.9 bits (217), Expect = 1e-16
 Identities = 92/420 (21%), Positives = 184/420 (42%), Gaps = 43/420 (10%)

Query: 1   MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60
           M  A  ++ +I +  ++AKIG        +P V+G++  G++L    +  I      P+ 
Sbjct: 36  MSLAIIVISSISIGNLVAKIG--------IPKVIGQITAGIILSPNAFGKIQIPLLFPLG 87

Query: 61  MGS-------SEVIDFLAKLGIIFLLFLGALDTDVEQLKK---TGLTATISTLMGVFVPL 110
           +         +E I  ++ +  I LLF   L+TD++   K    G    I+ ++G F   
Sbjct: 88  ITQIGENYLINEKIFAISTIASIILLFTAGLETDLKLFIKFLPRGGIIGITEVVGTFTSF 147

Query: 111 ILGYFALRYMGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFL 170
           +L    +  +      +   G++ T TS G+   ++     + +  G   +S S++DD L
Sbjct: 148 VLMASIIFNVPLISPTSLFIGIIGTPTSAGIAASILSAKKKMSTSEGVTIISTSIIDDVL 207

Query: 171 GIALIIFAVG-SGSLLGLSMKIIAFFIITGILGW--------YSIDKYIRFAERLHVEKG 221
            + ++   +  S S+  L +      I+  I+ W        Y  +   R  ++L+    
Sbjct: 208 SMLMLTSVITISRSISDLDIASSIKAIVQNIVIWLCLTFSLIYISETLSRLLKKLNSVTL 267

Query: 222 ILGMAVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFF 281
              + + +    A++ +    + + G+++ GL +SK  +   ++++  +I     IPIFF
Sbjct: 268 ATVITLSLALTIASIFQNLGMSFVVGAYVFGLAMSKT-DIVYVIQDKLTIFERFFIPIFF 326

Query: 282 IHTGAMLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKM 341
              G M ++    + + + L L +S IA+I K        +I A       LF   N   
Sbjct: 327 TSIGLMSDINEILSKEVLILGLAISAIAIITK----SIFCFIPA-------LFLGFNKLG 375

Query: 342 SLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFR 401
           +L++  G +PR EV+L+   VA+  G IS     K     +I + +  +I  P++ + F+
Sbjct: 376 ALKIATGMVPRGEVSLIMANVALSSGFIS----QKIFGIIIIMVFLPTIIATPIINFLFK 431


>pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana
           >gi|7629992|emb|CAB88334.1| (AL132960) putative protein
           [Arabidopsis thaliana]
           Length = 842
           
 Score = 88.2 bits (215), Expect = 2e-16
 Identities = 78/345 (22%), Positives = 162/345 (46%), Gaps = 43/345 (12%)

Query: 8   LFTIGVALILA--KIGDAIIERFELPGVLGELIMGMLLG------NLVYFGIVSKDYLPI 59
           L  +  ALI+A  +    + +    P V+ E++ G+LLG      N+ Y   +   +   
Sbjct: 28  LLIVQTALIIAVSRFLAVLFKPLRQPKVIAEIVGGILLGPSALGRNMAYMDRIFPKW--- 84

Query: 60  TMGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILG------ 113
              S  +++ +A +G++F LFL  L+ D+  ++++G  A    + G+ +P I G      
Sbjct: 85  ---SMPILESVASIGLLFFLFLVGLELDLSSIRRSGKRAFGIAVAGITLPFIAGVGVAFV 141

Query: 114 -----YFALRYMGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD 168
                Y A    GY+    F  GV L+ T+  +  R++ +L +L +++G  +++A+  +D
Sbjct: 142 IRNTLYTAADKPGYAEFLVFM-GVALSITAFPVLARILAELKLLTTQIGETAMAAAAFND 200

Query: 169 ---FLGIALIIFAVGSGSLLGLSMK--IIAFFIITGILGWYSIDKYI------RFAERLH 217
              ++ +AL +   G+G   G   K  +++ +++    G+      +        A+R  
Sbjct: 201 VAAWILLALAVALAGNGGEGGGEKKSPLVSLWVLLSGAGFVVFMLVVIRPGMKWVAKRGS 260

Query: 218 VEKGILGMAVGMMFLFAALAEGWFA-----AAIEGSFMMGLILSKLPE-GKRIMEEVRSI 271
            E  ++  +   + L   +  G+        +I G+F+ GL + K  E G+R++E +   
Sbjct: 261 PENDVVRESYVCLTLAGVMVSGFATDLIGIHSIFGAFVFGLTIPKDGEFGQRLIERIEDF 320

Query: 272 GYGLLIPIFFIHTGAMLNLTVFRNADAIKLALVLSTIAVIGKVAG 316
             GLL+P++F  +G   ++   R A++  +  ++   A  GK+ G
Sbjct: 321 VSGLLLPLYFATSGLKTDVAKIRGAESWGMLGLVVVTACAGKIVG 365


>gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]
           Length = 505
           
 Score = 85.8 bits (209), Expect = 9e-16
 Identities = 75/309 (24%), Positives = 144/309 (46%), Gaps = 21/309 (6%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
           L  +G+ LI AKI + I  R  L   +G ++MG+LLGN V FG++           +E+I
Sbjct: 9   LLYLGIMLIAAKISEEIFRRIGLVTFVGPILMGILLGNGV-FGVIQ---------INEII 58

Query: 68  DFLAKLGIIFLLFL-GALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHRE 126
            F+  LGI+FLLFL GA + +VE   +      ++ ++   +P  +   A+  +G+ +  
Sbjct: 59  SFITSLGIVFLLFLAGAEEFNVE--NRPNANVFLAVILESIIPFSVILVAIYIIGFKNYL 116

Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGSLLG 186
                V L  +S G   R++MD+ +  + +        ++ + + + L    + +  +L 
Sbjct: 117 ILI--VPLAMSSAGPLSRMLMDVKISDNRISNLIFQQVILIEIIFVILFAILLKTSEILI 174

Query: 187 LSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGI-LGMAVGMMFLFAALAEGW-FAAA 244
             ++I   F  T + G  ++ K +   E     + I     + ++ +   LAE + F +A
Sbjct: 175 TIIEIFLVFAFTIMFG-RTLAKILEKIEYYFKAREIEFASLIAIILIIGYLAELYKFNSA 233

Query: 245 IEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLALV 304
           I   F+  L+   L +   ++E + +  YG   P+FF+  G  +      NA  I  +L+
Sbjct: 234 ISAFFLGILLKDYLKDRPELLERLHAFTYGFFEPLFFLGIGLYVTKI---NASIILFSLL 290

Query: 305 LSTIAVIGK 313
             ++ +  K
Sbjct: 291 FFSLIIASK 299


>pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis
           >gi|2226151|emb|CAA74453.1| (Y14080) hypothetical
           protein [Bacillus subtilis] >gi|2633321|emb|CAB12825.1|
           (Z99109) similar to Na+/H+ antiporter [Bacillus
           subtilis]
           Length = 408
           
 Score = 85.4 bits (208), Expect = 1e-15
 Identities = 97/415 (23%), Positives = 178/415 (42%), Gaps = 57/415 (13%)

Query: 1   MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLG-NLVYFGIVSKDYLPI 59
           M P   ++F +G AL+L  I   I  + +   +   +++GML+G +    GI+   ++  
Sbjct: 1   MSPMDHLVFEVGTALVLVAIASVIANKIKFSIIPFLIVLGMLVGPHAPKMGIIDLTFIQ- 59

Query: 60  TMGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRY 119
              SSE+I+F  ++G++FLLF   L+  V +L K+G +  +   + + +   LG      
Sbjct: 60  ---SSEIIEFFGRMGVLFLLFYLGLEFSVGKLIKSGKSIAVGGTIYILINFSLGLLYGFI 116

Query: 120 MGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD-FLGIALIIFA 178
            G+S  E      ++T +S  +  +V++DL    +      L   + +D FL + L   +
Sbjct: 117 TGFSFLEVLILAGVITISSSAIVAKVLVDLKRTANPETELILGIIMFEDIFLAVYL---S 173

Query: 179 VGSGSLLG---------LSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGM 229
           V SG +LG         LS+ I   +++   +    +   +     +   +  + +    
Sbjct: 174 VVSGLILGDATSVGSALLSILIAFGYMLLFFIAARKLPPLLNKLLDIRSNEVFIIVIFAA 233

Query: 230 MFLFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIP-------IFFI 282
           +F  A  +E    A   G+ ++GL+ S+     RI          L++P       +FF 
Sbjct: 234 LFFIAGFSETIHVAEAIGALLLGLVFSETEHSDRIEH--------LVVPFRDFFGAMFFF 285

Query: 283 HTGAMLNLTVFRNADAIKLAL--VLSTIA---VIGKVAGRGFGAWITAWGRGRDFLFTRE 337
             G  L++  F   +A+ LAL  V+ TI    + G VAGR  G                 
Sbjct: 286 SFG--LSIDPFSLGEAVWLALGAVILTILGNFIAGMVAGRRAGL---------------- 327

Query: 338 NFKMSLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLIT 392
           + K S  +G+  + R E +++   + I GG +S    P      LI   +  L+T
Sbjct: 328 SHKASSNIGLTIVSRGEFSIIVANLGIAGG-LSATLKPFAALYVLILAILGPLVT 381


>pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus
           >gi|2983090|gb|AAC06696.1| (AE000689) NA(+)/H(+)
           antiporter [Aquifex aeolicus]
           Length = 387
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 83/318 (26%), Positives = 142/318 (44%), Gaps = 42/318 (13%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
           L  + ++  LA +   I+    +P  +GELI G+L+GN  + GI     +P      E++
Sbjct: 13  LIIVFLSAFLAPLFSRILR---MPVPVGELIFGILIGNF-FVGI----QVP------EIL 58

Query: 68  DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM-GYSHRE 126
           +FL+  G + L+FL  L+ D   ++K            V++  +L  F   ++ G     
Sbjct: 59  NFLSDFGFLLLMFLAGLELDFNLIEKADKKQN-----AVYISYVLLIFLSAFVFGILLGI 113

Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAV------G 180
             A  ++L+  S+GL V  + D+ VL        L   V  + + +  +          G
Sbjct: 114 GTAPAIILSLISLGLMVATLKDMSVLEEPFAKKVLLIGVFGEIISLLALTLMEKLLHFHG 173

Query: 181 SGSLLGLSMKIIAFFI-------ITGILGWYSIDKYIRFAERLHVEK--GILGMAVGMMF 231
             SL+     I  FF        +T +L W+    Y     RL  E+    LG+ + +  
Sbjct: 174 FVSLIKELGVIFVFFFSFFLGFYLTRLLVWW----YPEIVNRLTYEEDPSALGIRLSLFL 229

Query: 232 LFAALAEGWFAA--AIEGSFMMGLILSK-LPEGKRIMEEVRSIGYGLLIPIFFIHTGAML 288
           +F +      A   ++ G+FM G++ S  + E K + E++ SIGYG LIPIFFI TG  +
Sbjct: 230 MFTSSIFAKLAGIESVLGAFMAGVVFSYFIREKKDLEEKLSSIGYGFLIPIFFIKTGMGM 289

Query: 289 NLTVFRNADAIKLALVLS 306
            +     A   K+ + L+
Sbjct: 290 EVAGLNLAILFKVFIFLA 307


>gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40309|YJJ4_YEAST
           HYPOTHETICAL 97.1 KD PROTEIN IN BCK1-TOK1 INTERGENIC
           REGION >gi|630170|pir||S46584 probable membrane protein
           YJL094c - yeast (Saccharomyces cerevisiae)
           >gi|521094|emb|CAA54359.1| (X77087) 12 transmembrane
           domains; J0909 ORF [Saccharomyces cerevisiae]
           >gi|1008268|emb|CAA89387.1| (Z49369) ORF YJL094c
           [Saccharomyces cerevisiae]
           Length = 873
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 96/425 (22%), Positives = 173/425 (40%), Gaps = 45/425 (10%)

Query: 3   PATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG 62
           P T  LF   + L++  +          P V+ E+I G++LG  ++  I +         
Sbjct: 22  PLTLFLFQACLILLVCNLIHIPFSMMRQPKVISEVISGVILGPTIFGQIPNYTNTIFPTS 81

Query: 63  SSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILG--------- 113
           S   ++ +A LGII  +F   L+ D+  +KK    A +  ++ + VP   G         
Sbjct: 82  SIPGLNLVANLGIILFMFFLGLEVDIAFIKKHLKKALVIGIVTLAVPFGFGCLLAIPLFH 141

Query: 114 YFALRYMGYSHREAFAGGVLLTATSIGLTV-----RVMMDLGVLRSEVGAASLSASVMDD 168
            +A +  G  H + F+  ++  A SI +T      R++ +L +++   G   L+A +++D
Sbjct: 142 TYANKTEGERHIK-FSVFMVFIAVSISVTAFPVLCRILNELRLIKDRAGIVVLAAGIIND 200

Query: 169 FLGIALIIFAVGSGSLLGLSMKIIAFFIITGILGWYSID----KYIR--FAERLH-VEKG 221
            +G  L+  ++   S  G  +  +   +IT    W+ I     KY+      R H +++ 
Sbjct: 201 IMGWILLALSIILSSAEGSPVNTVYILLIT--FAWFLIYFFPLKYLLRWVLIRTHELDRS 258

Query: 222 ILGMAVGMMFLFAALAEGWFAAAIE-----GSFMMGLILSKLPE-GKRIMEEVRSIGYGL 275
                  M  LF      +F   I      G+F+ GL++ +      ++ E +  I   +
Sbjct: 259 KPSPLATMCILFIMFISAYFTDIIGVHPIFGAFIAGLVVPRDDHYVVKLTERMEDIPNIV 318

Query: 276 LIPIFFIHTGAMLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFT 335
            IPI+F   G  ++LT+               IA+  K+      A +T        LF 
Sbjct: 319 FIPIYFAVAGLNVDLTLLNEGRDWGYVFATIGIAIFTKIISGTLTAKLTG-------LFW 371

Query: 336 RENFKMSLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPL 395
           RE     + M    I    V +V L V ++ G IS     K     ++   VS  +T PL
Sbjct: 372 REATAAGVLMSCKGI----VEIVVLTVGLNAGIIS----RKIFGMFVLMALVSTFVTTPL 423

Query: 396 LKWAF 400
            +  +
Sbjct: 424 TQLVY 428


>pir||F69201 conserved hypothetical protein MTH760 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621849|gb|AAB85263.1| (AE000854) Na+/H+-exchanging
           protein:Na+/H+ antiporter [Methanobacterium
           thermoautotrophicum]
           Length = 399
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 99/426 (23%), Positives = 190/426 (44%), Gaps = 54/426 (12%)

Query: 6   WILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSE 65
           ++ F++ V ++L  + + +  R  LPG+LG LI+G+L+G      ++SK  + I+     
Sbjct: 3   YVAFSVAVIILLGLLFNRVFTRARLPGILGMLILGILIGP-HGLNLISKSIMDISPD--- 58

Query: 66  VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTAT-ISTLMGVFVPLILGYFALRYMGYSH 124
               L  + +I +L       ++E L+K G+TA  +S +  VF  L +   +   +G   
Sbjct: 59  ----LRVIALIIILLRAGFGINLESLRKVGMTAVKMSFIPDVFEGLAVMVASHYILGLPI 114

Query: 125 REAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAAS------LSASVMDDFLGIAL--II 176
            EA   G ++ A S  + V  M  L  +   +G A       L+ + +DD + I L  + 
Sbjct: 115 IEAGILGFVIAAVSPAVIVPQM--LSFIERRMGTAKGIPTIILTGASVDDVVSITLFSVF 172

Query: 177 FAVGSGSLLGLSMKIIA--FFIITGILGWYSIDKYI----RFAERLHVEKG--ILGMAVG 228
             +  G  + L ++ I     I+TGI G  ++   +    R  E  + EK   ILG A+ 
Sbjct: 173 LGIYQGQQVNLLVEAIGVPLSILTGITGGLALGLALVYLFRRFEIRNTEKTLIILGAAIL 232

Query: 229 MMFLFAALAEGWFAAAIEGSFMMGL-ILSKLPE-GKRIMEEVRSIGYGLLIPIFFIHTGA 286
           +  +   ++     AA+ G  ++GL IL ++PE G ++ E+   +     I + F+  GA
Sbjct: 233 LKNMGDLISTYLPIAALVGVMVVGLVILERMPETGLKLSEKFNKVWIFAEI-LLFVLVGA 291

Query: 287 MLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMG 346
            +++ +  +   + LA++ + + V      R  G  ++   +G D     + F +S    
Sbjct: 292 QVDVRLIFHVGLLGLAVITAGLMV------RSIGVLLSL--KGTDLNLKEKVFCIS---- 339

Query: 347 IGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPL----LKWAFRE 402
              IP+  V      + +  G  + + +       L    +++L T PL    +KW    
Sbjct: 340 -AYIPKATVQAAIGAIPLAAGVAAGETI-------LAMAVLAILFTAPLGSLAVKWTGER 391

Query: 403 EVEAQR 408
            +E +R
Sbjct: 392 FLEVER 397


>gb|AAD30610.1|AC007153_2 (AC007153) similar to Na/H antiporter proteins [Arabidopsis
           thaliana]
           Length = 855
           
 Score = 74.1 bits (179), Expect = 3e-12
 Identities = 96/407 (23%), Positives = 175/407 (42%), Gaps = 42/407 (10%)

Query: 30  LPGVLGELIMGML-----LGNLVYFGIVSKDYLPITMGSSEVIDFLAKLGIIFLLFLGAL 84
           LP  + +++ G+L     LGN   F I        TM    V++  A L +++ +FL  L
Sbjct: 77  LPPFVAQILCGLLFSPSVLGN-TRFIIAHVFPYRFTM----VLETFANLALVYNIFLLGL 131

Query: 85  DTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFAGGVLLTATSIGLT-- 142
             D+  ++ T L   I    G+ V L +G F     G  H +    G +  + ++  T  
Sbjct: 132 GMDLRMVRITELKPVIIAFTGLLVALPVGAFLYYLPGNGHPDKIISGCVFWSVALACTNF 191

Query: 143 ---VRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGSLLGLSMKIIAFFIITG 199
               R++ DL +LRS++G  ++ A+++ D     L++F   S S  G   K++ F IIT 
Sbjct: 192 PDLARILADLKLLRSDMGRTAMCAAIVTDLCTWVLLVFGFASFSKSGTWNKMMPFVIITT 251

Query: 200 ILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLP 259
            +        IR        K +     G + L   + +     +I G+F+ GL +    
Sbjct: 252 AIFVLLCIFVIRPGIAWIFAKTV---KAGGVVLCGLITDACGVHSITGAFLFGLSIPHDH 308

Query: 260 EGKRIMEE-VRSIGYGLLIPIFFIHTGAMLNL-TVFRNADAIKLALVLSTIAVIGKVAGR 317
             + ++EE +     G+L+P+F+I  G   ++  + +  D   + +V+ +  ++  V   
Sbjct: 309 IIRNMIEEKLHDFLSGILMPLFYIICGLRADIGFMLQFTDKFMMVVVICSSFLVKIVT-- 366

Query: 318 GFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKF 377
                IT+       LF   +  M     IG++  T+  L  L+V   G      D P +
Sbjct: 367 ---TVITS-------LFM--HIPMRDAFAIGALMNTKGTL-SLVVLNAGRDTKALDSPMY 413

Query: 378 IAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIEKKKK 424
              T+  + +S L+  PLL +A++       K ++   K R  +K K
Sbjct: 414 THMTIALLVMS-LVVEPLLAFAYKP------KKKLAHYKHRTVQKIK 453


>pir||T36239 probable integral membrane efflux protein - Streptomyces coelicolor
           >gi|4582390|emb|CAB40337.1| (AL049573) putative integral
           membrane efflux protein [Streptomyces coelicolor A3(2)]
           Length = 404
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 77/302 (25%), Positives = 135/302 (44%), Gaps = 29/302 (9%)

Query: 3   PATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG 62
           P T +L  +  A++   +  A   R  +P V+ E+ +G+++G  V  G    D       
Sbjct: 4   PGTLVLI-LAAAVLAPLLVHATGRRVRVPLVIFEISLGIVMGPDV-LGWARPD------- 54

Query: 63  SSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGY-FALRYMG 121
             +V+D LA LG+  L+FL   + D   ++   L  ++ +     V L+ G   AL   G
Sbjct: 55  --DVVDTLADLGLSMLIFLAGYEIDFAAVRGDTLRRSLWSWP---VALVAGIALALLVSG 109

Query: 122 YSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGS 181
               EAF  G  LT+T++G  + ++ D G LR   G    +   + +F G  + +  + S
Sbjct: 110 GDVFEAFVIGTALTSTTLGTVLPMLRDSGELRGRFGTVISAFGAVGEF-GPVIAVALLLS 168

Query: 182 GSLLGLSMKIIAFF--IITGILGWYSIDK---YIRFAERLHVEKGILGMAVGMMFL--FA 234
           G     S  ++A F  I T  + W    +   + R  ER     G   +   M+ L    
Sbjct: 169 GRRPAESAALLAAFGAITTAAVFWALRPRPPWFARLTERTLHTSGQFAVRFVMLLLACML 228

Query: 235 ALAEGWFAAAIEGSFMMG-----LILSKLPEGK-RIMEEVRSIGYGLLIPIFFIHTGAML 288
            LAE +    + G+F  G     ++L   P     ++ +V ++G+G L+P+F++ TG   
Sbjct: 229 GLAEVFGLDVLLGAFAAGVLTRLVLLRAAPASSGEVLGKVEAMGFGFLVPLFYVVTGIEF 288

Query: 289 NL 290
           +L
Sbjct: 289 DL 290


>pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum pernix  (strain K1)
           >gi|5106130|dbj|BAA81441.1| (AP000064) 412aa long
           hypothetical Na+/H+ antiporter [Aeropyrum pernix]
           Length = 412
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 68/278 (24%), Positives = 127/278 (45%), Gaps = 33/278 (11%)

Query: 31  PGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFLAKLGIIFLLFLGALDTDVEQ 90
           PGV+ E+IMG +L    ++G+ S          +EV+  LA +G   LLF+   + D+  
Sbjct: 82  PGVV-EIIMGAMLA---FWGVKS----------TEVLTLLAAIGANLLLFMAGSEIDLAL 127

Query: 91  LKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFAGGVLLTATSIGLTVRVMMDLG 150
           L+     A I  L+    PL L      Y+G S   +      L+ATS+ LT  ++    
Sbjct: 128 LRSILPQAVIVALVSALAPLALTALLHVYLGLSLTSSLVILASLSATSVALTYLLLSSYR 187

Query: 151 VLRSEVGAASLSASVMDDFLGIALIIFAVGSGS-----LLGLSMKIIAFFIITGILGWYS 205
           ++RS +G  +L+++++ D  G+ ++  A  S S      + + +  +  + +   LG   
Sbjct: 188 LVRSRLGQLALASAMLLDLSGMIMLNIATASISPSLAFYIVILLAALLLYPLLPRLGGAP 247

Query: 206 IDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLPEGK-RI 264
            +  IR      +  G L   VG+              ++  SF++G+I S+    + ++
Sbjct: 248 FEAEIRLITMTVIILGFLSDFVGV-------------HSVLTSFILGVIASETVRTRVQL 294

Query: 265 MEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLA 302
            E++ S+  G   P FFI +G  ++  +  +  A+ LA
Sbjct: 295 REKLESLATGFFTPFFFIASGMSIDPGIPLHYVALALA 332


>gb|AAD32281.1|AC006533_5 (AC006533) putative Na+/H+ antiporter [Arabidopsis thaliana]
           Length = 735
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 79/376 (21%), Positives = 163/376 (43%), Gaps = 41/376 (10%)

Query: 66  VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHR 125
           +++  A L +++ +FL  L  D+  +K   +   I  ++G+   L+ G            
Sbjct: 2   LLETFANLALVYNVFLLGLGLDLRMIKIKDIKPVIIAIVGLLAALLAGAGLYYLPSNGEA 61

Query: 126 EAFAGGVLLTATSIGLT-----VRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG 180
           +    G +  + + G T      R++ DL +LR+++G  ++ A+V+ D     L IF + 
Sbjct: 62  DKILAGCMYWSIAFGCTNFPDLARILADLKLLRTDMGHTAMCAAVVTDLCTWILFIFGMA 121

Query: 181 SGSLLGLSMKIIAFFIITGI----LGWYSIDKYIRFAERLHVEKGILG-----MAVGMMF 231
             S  G+  +++ + + + I    L ++ I   + +     VE G +G       +  + 
Sbjct: 122 IFSKSGVRNEMLPYSLASTIAFVLLCYFVIQPGVAWIFNNTVEGGQVGDTHVWYTLAGVI 181

Query: 232 LFAALAEGWFAAAIEGSFMMGLILSKLPEG----KRIMEEVRSIGYGLLIPIFFIHTGAM 287
           + + + E     +I G+F+ GL    +P      K I E++     G+L+P+F+I  G  
Sbjct: 182 ICSLITEVCGVHSITGAFLFGL---SIPHDHIIRKMIEEKLHDFLSGMLMPLFYIICGLR 238

Query: 288 LNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGI 347
            ++       ++ +  V+++ +V+ K+    F +           +F R   +  L +G 
Sbjct: 239 ADIGYMNRTVSVGMMAVVTSASVMVKILSTMFCS-----------IFLRIPLRDGLAIGA 287

Query: 348 GSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQ 407
               +  +ALV L       A+   DV  +   TL F+ +S ++  PLL  A++      
Sbjct: 288 LMNTKGTMALVILNAGRDTKAL---DVIMYTHLTLAFLVMS-MVVQPLLAIAYK-----P 338

Query: 408 RKARIESRKERIEKKK 423
           +K  I  +   I+K K
Sbjct: 339 KKKLIFYKNRTIQKHK 354


>pir||F70591 probable kefB protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|2072703|emb|CAB08337.1| (Z95121) kefB [Mycobacterium
           tuberculosis]
           Length = 385
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 96/407 (23%), Positives = 172/407 (41%), Gaps = 44/407 (10%)

Query: 1   MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60
           ME +  +LF +GV L +  +  A+  RF L  +   L+ G+ LGN    G+ +      T
Sbjct: 1   MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60

Query: 61  MGSSEVIDFLAKLGIIFLL--FLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALR 118
                V+  L  LG+ F    F  +L      L   G+   ++   G     +LG   + 
Sbjct: 61  GAPIGVVLLLLALGLEFSATEFASSLR---HHLPSAGVDIVLNATPGAVAGWLLGLDGVA 117

Query: 119 YMGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDF-LGIALIIF 177
            +G +       GV   ++S G+  R++ DL  L +    A LS  V++DF +   L +F
Sbjct: 118 ILGLA-------GVTYISSS-GVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLF 169

Query: 178 AVGSGSLLGLSMKIIAFFIITGILGWYSID-KYIRFAERLHV---EKGILGMAVGMMFLF 233
           AV +     L   +     I  +LG ++   ++     RL      + +L   +G+  + 
Sbjct: 170 AVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIV 229

Query: 234 AALAEGWFAAAIEGSFMMGLILS--KLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLT 291
           AA+AE   A+A  G+F++GL L+       + ++  +R     L   IFF+  G  L++ 
Sbjct: 230 AAVAESLHASAAVGAFLVGLTLTGETADRARMVLTPLRD----LFATIFFLGIG--LSVD 283

Query: 292 VFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIP 351
             +    + +AL L+ +    KVA   F A      R           +  L+ G   + 
Sbjct: 284 PGKLVSMLPVALALAAVTAATKVATGMFAARREGVAR-----------RGQLRAGTALVA 332

Query: 352 RTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKW 398
           R E +L+  ++ + G +I     P   A    ++ V  ++ P L ++
Sbjct: 333 RGEFSLI--IIGLAGASI-----PGVAALATAYVFVMAIVGPILARY 372


>pir||A81330 probable glutathione-regulated potassium-efflux system protein
           Cj1231 [imported] - Campylobacter jejuni (strain NCTC
           11168) >gi|6968664|emb|CAB73485.1| (AL139077) putative
           glutathione-regulated potassium-efflux system protein
           [Campylobacter jejuni]
           Length = 541
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 86/395 (21%), Positives = 173/395 (43%), Gaps = 44/395 (11%)

Query: 8   LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
           L T+ +A++L    + I ++FE+P ++G +  G ++  + +             G  E I
Sbjct: 9   LITVAIAIVL----NVIFKKFEIPTIIGYIAAGEIISEIYHLS-----------GKGE-I 52

Query: 68  DFLAKLGIIFLLFLGALDTDVEQL----KKTGLTATISTLMGVFVPLILGYFALRYMGYS 123
             +A+ GI+FL+F   L+   + L    ++  L  ++  L   FV ++L   A+  +G  
Sbjct: 53  THIAEFGIVFLMFTIGLEFSFKHLMAMKQEVFLNGSLQMLTCGFVFMLL---AIGILGLG 109

Query: 124 HREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI----IFAV 179
            + A   G  L  +S  + ++++ D G +  + G  +L   +  D   I L+    IF+ 
Sbjct: 110 DKSATIVGFALALSSTAVVLKILNDNGDINEQYGRKALGILLFQDIAVIPLLLLVDIFSS 169

Query: 180 GSGSL--LGLSMKIIAFFIITGI--LGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAA 235
            + ++  L  +  I A  +IT +  +G Y +D+  R       ++  +   + M+   + 
Sbjct: 170 NNQNIEKLLFTSLISALILITLLFFIGKYLVDRIFRLIIHTSSQEIFISTVLFMVIGASF 229

Query: 236 LAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRN 295
           LA  +  +   G+F+ G ++++     +I  ++      LL+ +FFI  G  + L V   
Sbjct: 230 LANYFGFSYSLGAFIAGALIAETKYKHKIEADLIPF-RDLLLGLFFITVGMQIQLDVV-- 286

Query: 296 ADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEV 355
           A    L +VL T+ V+    G  FG           FL+T++   +     I  I    +
Sbjct: 287 AQNWFLIIVL-TLLVMALKFGIVFGFL---------FLYTKKRVALKTAFAIAQIGEFAL 336

Query: 356 ALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVL 390
           A+  L+ A +   I    +   ++   + IT  +L
Sbjct: 337 AIFSLLQAKNMLDIKTSQILIVVSILTMIITPFIL 371


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.328    0.145    0.418 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 141537896
Number of Sequences: 2977
Number of extensions: 5738030
Number of successful extensions: 22318
Number of sequences better than 1.0e-10: 42
Number of HSP's better than  0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 22193
Number of HSP's gapped (non-prelim): 48
length of query: 426
length of database: 189,106,746
effective HSP length: 54
effective length of query: 372
effective length of database: 156,788,448
effective search space: 58325302656
effective search space used: 58325302656
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 166 (69.1 bits)