BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0390 (napA-2) DE:Na+/H+ antiporter (napA-2) (426 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abys... 826 0.0 pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus hori... 720 0.0 pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abys... 230 3e-59 pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus hori... 224 2e-57 gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus] 182 7e-45 pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus hori... 180 2e-44 gb|AAB40041.1| (U17283) putative spore germination apparatus pro... 180 4e-44 pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abys... 177 2e-43 pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp... 155 7e-37 sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A4211... 149 7e-35 emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus la... 129 8e-29 pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298... 126 4e-28 gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus] ... 120 3e-26 gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus] 111 1e-23 pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus hori... 104 2e-21 dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabi... 103 3e-21 pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp... 100 3e-20 pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abys... 100 4e-20 pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC... 99 7e-20 pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii... 99 9e-20 pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thalian... 99 9e-20 pir||C82955 probable sodium/proton antiporter PA5529 [imported] ... 99 9e-20 gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum] 99 1e-19 pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis >... 98 2e-19 emb|CAB45049.1| (AL078635) putative integral membrane ion antipo... 98 2e-19 dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arab... 92 1e-17 gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana] 91 2e-17 dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans] 91 3e-17 gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter ... 90 3e-17 pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spir... 89 1e-16 pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana... 88 2e-16 gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus] 86 9e-16 pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis >... 85 1e-15 pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298... 84 3e-15 gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40... 79 1e-13 pir||F69201 conserved hypothetical protein MTH760 - Methanobacte... 76 1e-12 gb|AAD30610.1|AC007153_2 (AC007153) similar to Na/H antiporter p... 74 3e-12 pir||T36239 probable integral membrane efflux protein - Streptom... 71 2e-11 pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum perni... 71 2e-11 gb|AAD32281.1|AC006533_5 (AC006533) putative Na+/H+ antiporter [... 70 4e-11 pir||F70591 probable kefB protein - Mycobacterium tuberculosis (... 70 5e-11 pir||A81330 probable glutathione-regulated potassium-efflux syst... 70 5e-11 >pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abyssi (strain Orsay) >gi|5458000|emb|CAB49490.1| (AJ248284) Na+/H+ antiporter (napA-2) [Pyrococcus abyssi] Length = 426 Score = 826 bits (2110), Expect = 0.0 Identities = 426/426 (100%), Positives = 426/426 (100%) Query: 1 MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60 MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT Sbjct: 1 MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60 Query: 61 MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM 120 MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM Sbjct: 61 MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM 120 Query: 121 GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG 180 GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG Sbjct: 121 GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG 180 Query: 181 SGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW 240 SGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW Sbjct: 181 SGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW 240 Query: 241 FAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIK 300 FAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIK Sbjct: 241 FAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIK 300 Query: 301 LALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDL 360 LALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDL Sbjct: 301 LALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDL 360 Query: 361 MVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIE 420 MVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIE Sbjct: 361 MVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIE 420 Query: 421 KKKKAR 426 KKKKAR Sbjct: 421 KKKKAR 426 >pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus horikoshii >gi|3258023|dbj|BAA30706.1| (AP000006) 425aa long hypothetical Na(+)/H(+) antiporter [Pyrococcus horikoshii] Length = 425 Score = 720 bits (1839), Expect = 0.0 Identities = 353/423 (83%), Positives = 396/423 (93%) Query: 4 ATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGS 63 ATWILFTIG A+I+AKIGD+I+ERFELPGVLGEL+MGM LGNLVYFG++ +YLPITMGS Sbjct: 3 ATWILFTIGTAIIIAKIGDSIVERFELPGVLGELLMGMALGNLVYFGLIKSEYLPITMGS 62 Query: 64 SEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYS 123 SEVIDFLAKLGII LLFLGALDTD+E+LK+TG+TA +ST+MGVFVPL LGY+ALR MGY Sbjct: 63 SEVIDFLAKLGIILLLFLGALDTDIEKLKRTGVTAVVSTIMGVFVPLALGYYALRVMGYG 122 Query: 124 HREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGS 183 +REAFAGGVLLTATSIGLTVR+MMDLG LRSEVGAASLSASV+DDFLGIALIIFAVGSGS Sbjct: 123 YREAFAGGVLLTATSIGLTVRIMMDLGALRSEVGAASLSASVIDDFLGIALIIFAVGSGS 182 Query: 184 LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAA 243 LL LS KII FFIITG+LGWY +D YI+FAE+LHVEKG+LG+ +G+MF+FAALAE WFAA Sbjct: 183 LLELSAKIIVFFIITGVLGWYLVDHYIKFAEKLHVEKGVLGLVIGLMFIFAALAEDWFAA 242 Query: 244 AIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLAL 303 AIEGSFM GLILSKLPEGKRIMEEVRSIGYG LIP+FF+HTGAMLNLTVF+N +A KLA Sbjct: 243 AIEGSFMAGLILSKLPEGKRIMEEVRSIGYGFLIPLFFVHTGAMLNLTVFKNIEAFKLAF 302 Query: 304 VLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVA 363 VL+TIAV+GKV GRGFGAW+TAWGRGR FLFT++NF+MSLQMGIGSIPRTEVALVDLMVA Sbjct: 303 VLTTIAVVGKVIGRGFGAWLTAWGRGRGFLFTKQNFRMSLQMGIGSIPRTEVALVDLMVA 362 Query: 364 IHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIEKKK 423 IHGGAIS +VPKFIAATLIFITVSVLITPPLLKWAF+EEVEAQ+ A++ESRKERIE+KK Sbjct: 363 IHGGAISSGNVPKFIAATLIFITVSVLITPPLLKWAFKEEVEAQKMAKLESRKERIERKK 422 Query: 424 KAR 426 KAR Sbjct: 423 KAR 425 >pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abyssi (strain Orsay) >gi|5459083|emb|CAB50569.1| (AJ248288) Na+/H+ antiporter (napA-3) [Pyrococcus abyssi] Length = 380 Score = 230 bits (580), Expect = 3e-59 Identities = 140/402 (34%), Positives = 224/402 (54%), Gaps = 35/402 (8%) Query: 7 ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEV 66 + + + L++AKI + R P LG+L+ G+++G L + SEV Sbjct: 3 VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIG---------PSLLDVVEYGSEV 53 Query: 67 IDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHRE 126 L++LG++ LLFL L+TDVE+ K GL+A I +MGVFVP +LGY GY + Sbjct: 54 -RLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLK 112 Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGS--- 183 A G +LTATS+GLT ++MD+ LR++VG L+A+++DD LGI ++ V S Sbjct: 113 ALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGK 172 Query: 184 -----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAE 238 + + +++ FFI+ ++G + + + +ER+ + + + A+ +M +FA LAE Sbjct: 173 VEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAE 232 Query: 239 GWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADA 298 + A I G+++ GL++S ++I +++ +IGY L IPIF + G ++ V +A Sbjct: 233 KFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGV 292 Query: 299 IKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALV 358 ALV S IAV+GK+ G GFGA L R ++Q+GIG IPR EVAL+ Sbjct: 293 --FALVYSLIAVVGKIIGCGFGA-----------LVARFKPIEAIQVGIGMIPRMEVALI 339 Query: 359 DLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAF 400 V + G ++ D +A + + ++ LITP LLKWAF Sbjct: 340 IANVGLKEGILTRGD----LAVPVTMVVITTLITPFLLKWAF 377 >pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus horikoshii >gi|3256692|dbj|BAA29375.1| (AP000001) 380aa long hypothetical Na(+)/H(+) antiporter [Pyrococcus horikoshii] Length = 380 Score = 224 bits (564), Expect = 2e-57 Identities = 140/402 (34%), Positives = 222/402 (54%), Gaps = 35/402 (8%) Query: 7 ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEV 66 +L + + L++AK+ ++ + P LG+LI G+++G L I S EV Sbjct: 3 VLLELAIILVVAKLFGYLMVKLGFPAALGQLIGGIIIG---------PSLLNIVEYSQEV 53 Query: 67 IDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHRE 126 FLA+LG+I LLFL L+TDVE+ K GL+A I MGVFVP +LGY GY Sbjct: 54 -RFLAELGVIILLFLAGLETDVEEFKHVGLSAFIVATMGVFVPFLLGYLIAIVYGYRSLA 112 Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGS--- 183 A G +LTATS+GLT ++M++ LR++VG L+A+++DD LGI ++ V S Sbjct: 113 ALFLGGILTATSVGLTTSILMEMKKLRTKVGTTILAAAIVDDVLGIIILTILVAMSSRGR 172 Query: 184 -----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAE 238 + + ++I FF++ +G + + + +E++ + + + A+ +M LFA LAE Sbjct: 173 VEIFDIEIILAEVIIFFLLGIFIGHPIVKEVLMLSEKITLPETVTTFAIVIMLLFAYLAE 232 Query: 239 GWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADA 298 + A I G+++ GL++S K++ +++ +IGY L IPIF + G ++ V A Sbjct: 233 KFQLAGITGAYLAGLLVSMSEGSKKVTDKMMTIGYSLFIPIFLVSIGIETDIKVLATAGV 292 Query: 299 IKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALV 358 A+V S IA+IGK+ G GFGA +T + +LQ+GIG IPR EVAL+ Sbjct: 293 --FAIVYSLIAIIGKIQGCGFGALVTKFKPAE-----------ALQVGIGMIPRMEVALI 339 Query: 359 DLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAF 400 V + G ++ +A + + V+ L+TP LLK AF Sbjct: 340 IANVGLKEGILTRGT----LAIPVTMVVVTTLVTPFLLKLAF 377 >gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus] Length = 387 Score = 182 bits (457), Expect = 7e-45 Identities = 118/408 (28%), Positives = 209/408 (50%), Gaps = 32/408 (7%) Query: 9 FTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVID 68 F I + L+ K+ + R P VLG+LI+G+++G V I + SE++ Sbjct: 7 FQIALILLSTKLAGDLSVRLGQPSVLGKLIVGIVIGPAVLGWIEN----------SELLT 56 Query: 69 FLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAF 128 L+ +G+I L+F+ L+TD+E+L ++ L G+ +P + GY + MG A Sbjct: 57 QLSNVGVILLMFMAGLETDLEELNANRNSSLAVALGGIILPFVGGYVSGLVMGMEQGNAV 116 Query: 129 AGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG-----SGS 183 G+LL ATS+ ++V+ + DLG +++ L A+V DD L + L+ FA+ + Sbjct: 117 FLGLLLCATSVSISVQTLRDLGKMKTRESTTMLGAAVFDDILVVILLAFAMSFLGTDDVN 176 Query: 184 LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAA 243 L + +K + FF ++GW + +R+ L V + I+ A+ + F FA E A Sbjct: 177 LTMVILKKVVFFASIILIGWKGVPAIMRWLSPLRVSESIVSAALIICFSFAYFGELLGIA 236 Query: 244 AIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLAL 303 I G+F G+ +S+ + ++V I Y + +P+FF+ G +N+T + I L Sbjct: 237 GIIGAFAAGIAISQTNYKHEVEKKVEPIAYAMFVPVFFVSIG--MNITFDGIGNQIWFIL 294 Query: 304 VLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVA 363 L+ IAV+ K+ G GFGA +T + + K S +G G + R EVAL+ Sbjct: 295 ALTVIAVLTKLIGCGFGARMTGF-----------DAKSSAIIGAGMVSRGEVALIIAGTG 343 Query: 364 IHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKAR 411 + G ++ D + A +I + ++ +ITPP+LK+ F + +A + ++ Sbjct: 344 LSSGLLAQD----YFTAIVIVVILTTMITPPMLKYTFGAKDKAMKASK 387 >pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus horikoshii >gi|3256522|dbj|BAA29205.1| (AP000001) 375aa long hypothetical Na(+)/H(+) antiporter [Pyrococcus horikoshii] Length = 375 Score = 180 bits (453), Expect = 2e-44 Identities = 121/398 (30%), Positives = 208/398 (51%), Gaps = 40/398 (10%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67 L + + L +AK I E+F P VLG+++ G+L+G ++ +E+I Sbjct: 4 LLLLAILLAVAKFSGWIFEKFNQPIVLGQILAGILMGLIIE--------------RNEII 49 Query: 68 DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127 A LG++ LLFL +++D+E+ KK G + +GV I G F + Y + A Sbjct: 50 IEFANLGVLMLLFLAGIESDLEEFKKVGKPGILVAGVGVLFAFIFG-FIVAYPFFDFGTA 108 Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGI---ALIIFAVGSGS- 183 G ++T TS+ +TV+V+M+LG LR+ G L+A+V+DD LGI ++I + GS Sbjct: 109 MLYGAVMTPTSVSITVKVLMELGKLRTREGTTILAAAVIDDVLGILVLTIVISTLREGSV 168 Query: 184 ----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEG 239 +L + +++ F + +G ++ R ++ + + AV + LFA LAE Sbjct: 169 HYDIILKILLEVAGFLAVFLYIGPVFMEDAFRRLSKIDLPEATTTFAVVFLVLFAYLAEH 228 Query: 240 WFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI 299 A+I G++++GL + + KRI + + ++GY + IP+FF+ G ++ A Sbjct: 229 LNLASILGAYLIGLSIGQTSYKKRIEDHMNTLGYSIFIPLFFVDVGMRIDPRFLLQAKV- 287 Query: 300 KLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVD 359 AL+ + IA++ KV G G GA++ + ++K SL++GIG IPR V L Sbjct: 288 -FALLYALIAMLSKVIGCGLGAYLANF-----------DWKSSLKIGIGMIPRLGVELAM 335 Query: 360 LMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLK 397 + A+ G D + +A T++F+T L+TP LLK Sbjct: 336 ITTAMASGIAGSDVLT--VAMTMVFLT--TLVTPLLLK 369 >gb|AAB40041.1| (U17283) putative spore germination apparatus protein [Bacillus megaterium] >gi|1589214|prf||2210362A grmA gene [Bacillus megaterium] Length = 386 Score = 180 bits (451), Expect = 4e-44 Identities = 120/403 (29%), Positives = 208/403 (50%), Gaps = 35/403 (8%) Query: 9 FTIGVALIL--AKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEV 66 F + +ALIL KI + R P VLG+L++G++LG V G + D + Sbjct: 3 FVLSLALILFATKIAGHLSVRLGQPSVLGKLLIGIILGPAV-LGWIHND---------QF 52 Query: 67 IDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHRE 126 + + +++G++ L+FL L+TD+EQLK+ A ++G+ +P I G+ G Sbjct: 53 VHYFSEIGVLLLMFLAGLETDLEQLKRNWKAAFAVAVLGIILPFIGGFGVGELFGLGATY 112 Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGI---ALIIFAVGSGS 183 + GVLL ATS+ +TV+V+ D+ L S G+ L A+V+DD L + A++I +G+G Sbjct: 113 SLFIGVLLCATSVSITVQVLKDMNRLNSREGSTILGAAVVDDVLVVVLLAIMISFLGTGE 172 Query: 184 LLGLSM---KIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW 240 + L + K + FFI + GW + K + + L V + ++ + + + F + A+ Sbjct: 173 EVSLGLLVGKKLIFFIGAVLAGWLVVPKVLDWLTNLKVTEPVVSIGLAICFGYVYFADLM 232 Query: 241 FAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIK 300 A I G+F G+ +S+ I +V I Y + +P+FF+ G LN++ D I Sbjct: 233 GMAGIIGAFAAGIAISQTSYRHTIESKVEPIAYAVFVPVFFVSIG--LNVSFEGVGDQIG 290 Query: 301 LALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDL 360 L+LS IAVI K+ G GA +T + + + SL +G G + R EVAL+ Sbjct: 291 FILLLSVIAVITKLVGGALGAKVTGF-----------STRSSLLIGSGMVSRGEVALIIA 339 Query: 361 MVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREE 403 + + +P++ + +I I ++ L+ PPL+K+ + E Sbjct: 340 ATGLQESLL----LPEYFTSAVIVIIITTLVAPPLIKYIIQSE 378 >pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abyssi (strain Orsay) >gi|5457567|emb|CAB49058.1| (AJ248283) Na+/H+ antiporter (napA-1) [Pyrococcus abyssi] Length = 375 Score = 177 bits (445), Expect = 2e-43 Identities = 118/398 (29%), Positives = 209/398 (51%), Gaps = 40/398 (10%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67 L + + L +AK+ + ERF P VLG++I G+++G L+ +E+I Sbjct: 4 LLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGLLIE--------------RNEII 49 Query: 68 DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127 A LG++ LLFL L++D E+ K+ G + + +GV + G F + Y + A Sbjct: 50 VEFANLGVLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFG-FLIAYPFFDFGTA 108 Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGI---ALIIFAVGSGS- 183 G ++T TS+ +TV+V+M+LG LR++ GA L+A+V+DD LGI ++I + GS Sbjct: 109 LLYGAIMTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSV 168 Query: 184 ----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEG 239 ++ + +++ F + LG ++ R ++ + + A+ + LFA LAE Sbjct: 169 HYDVIVEVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEH 228 Query: 240 WFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI 299 A+I G++++GL + + KRI + IGY + IP+FF+ G ++ +A Sbjct: 229 LNLASILGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFL--FEAK 286 Query: 300 KLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVD 359 A + + A+I KV G G GA+++ + +++ S+++GIG IPR V L Sbjct: 287 TFAFLYAVFAMISKVIGCGLGAYLSKF-----------DWRTSIKIGIGMIPRLGVELAM 335 Query: 360 LMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLK 397 + A+ G D + +A T++F+T LITP +L+ Sbjct: 336 ISTAMAAGVAGSDVLT--VAMTMVFLT--TLITPIMLR 369 >pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp. (strain PCC 6803) >gi|1001188|dbj|BAA10332.1| (D64001) NaH-antiporter protein [Synechocystis sp.] Length = 461 Score = 155 bits (389), Expect = 7e-37 Identities = 128/433 (29%), Positives = 214/433 (48%), Gaps = 59/433 (13%) Query: 7 ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLG----NLVYF---GIVSKDYLPI 59 +L ++ V +K+G + R LP VLGEL+ G+L+G L+ F G+ +D L I Sbjct: 32 VLLSLVVIYFASKLGGEVCLRLNLPPVLGELVGGVLVGVSALKLLLFPEGGLAPEDSLVI 91 Query: 60 T--MGS---------------SEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATIST 102 MGS SEVI +++LG+I LLF L++++++L + G A I Sbjct: 92 QLLMGSADLSPEAAQSVFSAQSEVISVISELGVIILLFEIGLESNLKELIRVGPQAAIVA 151 Query: 103 LMGVFVPLILGYFALRYM-GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASL 161 ++GV P LG L + G + A G LTATSIG+T +V+ ++ L S G + Sbjct: 152 VVGVVTPFSLGTIGLMTIFGVAAIPAIFAGAALTATSIGITAKVLAEINRLSSNEGQIII 211 Query: 162 SASVMDDFLGIALIIFAVGS---------GSLLGLSMKIIAFFIITGILGWYSIDKYIRF 212 A+V+DD LGI +++ VGS +++ L + F + + ++G Y+ Sbjct: 212 GAAVLDDILGI-IVLAVVGSLVKTGEIQISNIIYLILSATGFVVGSILIGRLLSPFYVSL 270 Query: 213 AERLHVEKGILGMAVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIG 272 R+ +L +++ + F+ + +A+ AI GSF GLIL++ + + + E++ + Sbjct: 271 VNRMKTRGQLLLVSICVAFVLSYIAQIVQLEAILGSFAAGLILAETEKREDLEEQILPLA 330 Query: 273 YGLLIPIFFIHTGA-----MLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWG 327 +P+FF+ GA +LN V N + + +A L +A++GKV GF T +G Sbjct: 331 -DFFVPVFFVCVGAKTDVSVLNPAVPANREGLIIAAFLILVAIVGKVV-TGF----TLFG 384 Query: 328 RGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITV 387 + L +G+G IPR EV LV V GA+ P AA ++ + V Sbjct: 385 KSE---------LNKLAIGVGMIPRGEVGLVFAGVGAASGALD----PATDAAIIVMVIV 431 Query: 388 SVLITPPLLKWAF 400 + + PP L+ F Sbjct: 432 TTFVAPPWLRAVF 444 >sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A42111 Na+/H+-exchanging protein NapA - Enterococcus hirae >gi|148316|gb|AAA24781.1| (M81961) NaH-antiporter protein [Enterococcus hirae] Length = 383 Score = 149 bits (372), Expect = 7e-35 Identities = 108/400 (27%), Positives = 205/400 (51%), Gaps = 36/400 (9%) Query: 15 LILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFLAKLG 74 L+ IG I RF +P V+G+L++G+LLG G V + L V DF +++G Sbjct: 11 LVATTIGSHISRRFGIPAVIGQLLVGVLLGQ-AGLGWVHPNIL--------VHDF-SEIG 60 Query: 75 IIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFAGGVLL 134 +I L+FL L++D+ LKK L+G+ P+ G+ ++ EA G++L Sbjct: 61 VILLMFLAGLESDLSLLKKYFKPGMFVALLGILFPVFFGWLTGEAFQVANNEAIFFGIIL 120 Query: 135 TATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG-----SGSLLGLSM 189 ATS+ ++V V+ +L V+ ++ G+ L ASV+DD L + ++ F++ S S L L + Sbjct: 121 AATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLVLSFSLSFLTGKSTSNLPLPL 180 Query: 190 KIIA---FFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAAAIE 246 ++ +F+ +L + + AE+++ I+ M++ + + LA+ +++ Sbjct: 181 LLLEQLFYFLFIFLLVKWIAPFLMSLAEKIYANSAIIIMSLVICLGMSYLADLIGLSSVI 240 Query: 247 GSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLALVLS 306 G+F G+ +S+ + V ++GY + IP+FF+ G ++ + F ++ I L+L+ Sbjct: 241 GAFFAGIAVSQTKVKHEVYNNVEALGYAVFIPVFFVSVGLEVDFSKF--SEQILFILILT 298 Query: 307 TIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVAIHG 366 +A++ K+ G GA F+ + +L +G G I R E+AL+ L + Sbjct: 299 LVAILTKLIGGYIGA-----------KFSSFSSNSALMVGAGMISRGEMALIILQIGQQS 347 Query: 367 GAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEA 406 I + + +I + +S LI+P +LK+ F ++V A Sbjct: 348 NLIE----NHYYSPLVIVVLLSTLISPLILKY-FTKKVYA 382 >emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus lactis] Length = 379 Score = 129 bits (320), Expect = 8e-29 Identities = 106/401 (26%), Positives = 196/401 (48%), Gaps = 34/401 (8%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67 + + + LI + I R ++P V+G++++G+L+ V G+V S V+ Sbjct: 4 ILQLTIVLIASLIATLASRRLKIPAVIGQMLVGILIAPSV-LGLVH---------SGHVL 53 Query: 68 DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127 + ++++G+I L+FL L++D+ LKK + + + GV VPLI+ GY + Sbjct: 54 EVMSEIGVILLMFLAGLESDLTVLKKNFKASMLVAIGGVIVPLIVFGLVAFSFGYGMSTS 113 Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI-IFAV----GSG 182 F G++ ATS+ +TV V+ + G L + G+ L A+V+DD L + ++ IF GSG Sbjct: 114 FFYGIVFAATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLILSIFTSFKNGGSG 173 Query: 183 SLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFA 242 + L + F + I ++ +F ++L + +A+ + + LA+ Sbjct: 174 THLFFQFLLELLFFAFLFVVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGM 233 Query: 243 AAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLA 302 +A+ GSF GL +S+ +I E +IGY + IP+FF+ + + I Sbjct: 234 SAVIGSFFAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWI--I 291 Query: 303 LVLSTIAVIGKVAGRGFGAWITAWGRGR-DFLFTRENFKMSLQMGIGSIPRTEVALVDLM 361 L+ + +A++ K +I A+ G+ + L T E S+ +G G I R E+AL+ Sbjct: 292 LLFTLLAILTK--------FIPAYFVGKSNKLSTGE----SMLIGTGMISRGEMALIVAQ 339 Query: 362 VAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFRE 402 + + AI D+V + +I TV + P L+K ++ Sbjct: 340 IGL-TSAIITDEVYSELVIVIILATV---LAPFLIKLVLKK 376 >pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus >gi|2983453|gb|AAC07034.1| (AE000714) Na(+)/H(+) antiporter [Aquifex aeolicus] Length = 408 Score = 126 bits (314), Expect = 4e-28 Identities = 118/417 (28%), Positives = 192/417 (45%), Gaps = 54/417 (12%) Query: 11 IGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFL 70 + + L AK+ +I + +P VLGE+ G++LG V G++ P+ SE I L Sbjct: 22 LAILLFSAKLFGSIFRKLGIPPVLGEVTAGVILGQSV-LGLI-----PL----SEAIKVL 71 Query: 71 AKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRY-MGYSHREAFA 129 A+LG+I LLF L+ D+ L + GL +T+ ++G +P G+ Y G + Sbjct: 72 AELGVILLLFEVGLEADINMLMRVGLWSTLVAIVGAALPFAGGFIVSYYFFGLDLVASLF 131 Query: 130 GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIF--------AVGS 181 G LTATSIG+TVRV+ DL + L A+V+DD +G+ ++ AV Sbjct: 132 MGGALTATSIGITVRVLTDLNKHKERFAQIVLGAAVLDDIMGVIILAALYEFSKTKAVHF 191 Query: 182 GSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWF 241 + + L + I+ FF+I + + K + A R + ++ ++ + L AA + F Sbjct: 192 DTTVNLIIHILMFFLIAPFVA-NVLAKLLSIAARKTQDMDLIPASIMALILLAAYSAHKF 250 Query: 242 AA-AIEGSFMMGLILSK---LPEGKRI---------MEEVRSIGYGLLIPIFFIHTGAML 288 + +I GSF GL LS+ +P + +EE + ++ PIFF+ G L Sbjct: 251 GSPSILGSFTAGLALSRRFVIPFAAMLRLDEKLLHKVEESITPLVWVMAPIFFVSVGLAL 310 Query: 289 NLTV--FRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMG 346 NL F + + + L +A+IGKV GF A + K +G Sbjct: 311 NLKAIDFSSPEFWTFSSALIVVAIIGKVLA-GFVA--------------PGSLKEKASIG 355 Query: 347 IGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREE 403 +PR EV L+ AI+ + A + + V+ LI P +LK +EE Sbjct: 356 FSMLPRGEVGLIFAEFGRSFKAINEVE----YAVIVFVVAVTTLIAPIVLKLLLKEE 408 >gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus] >gi|7451786|pir||A69277 Na+/H+ antiporter (napA-1) homolog - Archaeoglobus fulgidus >gi|2650426|gb|AAB91016.1| (AE001091) Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus] Length = 377 Score = 120 bits (298), Expect = 3e-26 Identities = 100/402 (24%), Positives = 191/402 (46%), Gaps = 52/402 (12%) Query: 10 TIGVALILAKIGDAIIERFELPGVLGELIMGMLLG----NLVYFGIVSKDYLPITMGSSE 65 TI + + A I I ++ +P V+ E+++GM+ G N++Y +SE Sbjct: 9 TIALISLTAFISPLIADKLRVPVVVLEIVLGMIFGVSFLNVIY--------------ASE 54 Query: 66 VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHR 125 + FL+ G+IFL+FL L+ D + + K+G + + + L + AL + + Sbjct: 55 WLSFLSLFGLIFLMFLAGLEIDADVVLKSGHLKRVVAFFALSLALSVALTALMGLNLFY- 113 Query: 126 EAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGSL- 184 ++LT ++G+ V V+ ++G+ + + G ++ +++ DF + L+ +G L Sbjct: 114 -----AIILTNVAVGVVVSVLREIGLEKEDFGQLNIVTALVSDFSTMFLLSIYFITGYLQ 168 Query: 185 LGLSMKIIAFFIITGILG----WYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGW 240 + + II F+ G W+ D R+ E G+ G ++ +M LF L+ Sbjct: 169 VAFAFLIILVFLAAYRFGKLVIWHFPDFISRWFSDEPSEIGVRG-SLAIMILFVGLSSLL 227 Query: 241 FAAAIEGSFMMGLILS-KLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI 299 AI G+F+ G++LS GK++ +++ +G+G IPIFFI TG+ LN+T Sbjct: 228 GVEAILGAFLAGVLLSITFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELNITQAGEGIGF 287 Query: 300 KLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVD 359 L L+ ++AV +G L NF + + +G + T+++L Sbjct: 288 ILLLLAVSVAV-----------------KGIPSLIFASNFGLRRAISMGMLQSTKLSLTI 330 Query: 360 LMVAIHGGAISPDDVPKFIAATLI-FITVSVLITPPLLKWAF 400 VAI +S + +F + L+ F +S L++P L ++ + Sbjct: 331 AGVAI---GVSSGVITEFESTALVTFTIISCLLSPTLFRFLY 369 >gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus] Length = 391 Score = 111 bits (276), Expect = 1e-23 Identities = 89/381 (23%), Positives = 182/381 (47%), Gaps = 27/381 (7%) Query: 1 MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60 M P LF + + ++LA+I ++++++ LP ++GEL+ GM++G ++++ Sbjct: 1 MNPIILALFDVSIFILLAEILSSLVQKYGLPKLIGELLAGMIIGPYALGSLLNQLLGFPL 60 Query: 61 MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM 120 +G + I+FLA+ +I L+F L+ + +K +G+ + G +P Y+ Sbjct: 61 IGINSYIEFLAEFSVILLIFASGLEHGIAPIKSSGILGFLGATFGALLPFFAAYY-FYIS 119 Query: 121 GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD-----FLGIALI 175 + A G + ATS+ V +++ G L+ + +S++ DD L + + Sbjct: 120 SFGLDSALILGTAMGATSLA-AVASIIEEGKLKGKGINFMVSSAAADDVVDLLLLSVVIA 178 Query: 176 IFAVGSGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERL---HVEKGILGMAVGMMFL 232 I S S+ +S+KIIA +I ++ SI + +R+ ++E+ L + G+ L Sbjct: 179 ILQGESTSVTSISLKIIALVVIWVVILVVSIILIPKITDRISDKYIEEFPLAVLFGLTLL 238 Query: 233 FAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTV 292 +L + I +F+ G+ + + +I +E+ S + P+FF++ GA +N Sbjct: 239 MVSLG----YSPIISAFVAGVAFANSVKNSKI-KEISSTLLSVFGPLFFVYIGAEVNFLT 293 Query: 293 FRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPR 352 N + + L+L L+ IA I K W+ + +L N K + + +G +PR Sbjct: 294 L-NLNTVILSLELTAIATIFK--------WLGIFPFALAYL---RNAKAANTVALGMVPR 341 Query: 353 TEVALVDLMVAIHGGAISPDD 373 E LV + + A++ ++ Sbjct: 342 GETGLVIASLGLSYNALNQEE 362 >pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus horikoshii >gi|3257347|dbj|BAA30030.1| (AP000004) 390aa long hypothetical Na(+)/H(+) antiporter [Pyrococcus horikoshii] Length = 390 Score = 104 bits (257), Expect = 2e-21 Identities = 96/414 (23%), Positives = 194/414 (46%), Gaps = 48/414 (11%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67 +F + + L++AK + ++++ + ++ ++ G++LG FG L I + +SE + Sbjct: 4 IFDLSILLVVAKSLEWLLKKKGIHPIIAHILTGIILGP---FG------LSIVLPTSE-L 53 Query: 68 DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127 L + G+I ++ L ++ + + + A++ + GV ILG+ + ++ S A Sbjct: 54 KVLGEFGLIMMMLYMGLTSNFSAISRNKVKASVVAMFGVAFSFILGFLTVYFLEKSLIAA 113 Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIAL--IIFAVGSGSLL 185 G+ L T+I +T V++ V + ++ + + A+ DD + + L I+ + G + Sbjct: 114 LFVGITLGNTAIEVTSGVLVRERV-KKDISSVLMGAAFADDIIAVYLIGILTGITQGGIS 172 Query: 186 GLSMKIIAFFIITGILGWYSIDKYI-----RFAERLHVEKGILGMAVGMMFLFAALAEGW 240 GLS+ + I+ ILG + +++ RF + + + F A +A+ Sbjct: 173 GLSLVFLTIKIVIFILGVLMLSEFVFKRSTRFYNIIRDLHIFFTFTIVLTFTLAFIAQDI 232 Query: 241 FAAAIEGSFMMGLILSKLPEGK-----------RIMEEVRSIGYGLLIPIFFIHTGAMLN 289 I G+++ GL +S+L E K ++EE+ + IP+FF++ G M N Sbjct: 233 GLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELIEELEIVLVEFFIPLFFVYVGLMFN 292 Query: 290 LTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGS 349 V +I L L+L AV+GK+ G G G I + + ++ +GIG Sbjct: 293 PNV--RDISILLILLLYASAVLGKLIGCGLGMKIFG-----------SSIRDAIIVGIGM 339 Query: 350 IPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFIT-VSVLITPPLLKWAFRE 402 R + L L + + G I + I AT++ ++ ++ L TP L ++ R+ Sbjct: 340 GGRGSLELAILKLGLEKGLID-----EGIFATVVIVSMLTALSTPVLFRYTVRK 388 >dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabidopsis thaliana] Length = 810 Score = 103 bits (255), Expect = 3e-21 Identities = 85/331 (25%), Positives = 162/331 (48%), Gaps = 28/331 (8%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG--SSE 65 + I + ++L ++ ++ P V+ E+I G++LG + SK +L S Sbjct: 35 ILQIVIVIVLTRVLAYLLRPLRQPRVIAEVIGGIMLGPSLLGR--SKAFLDAVFPKKSLT 92 Query: 66 VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGY---FALRYMGY 122 V++ LA LG++F LFL L+ D + L++TG A L G+ +P LG F L+ Sbjct: 93 VLETLANLGLLFFLFLAGLEIDTKALRRTGKKALGIALAGITLPFALGIGSSFVLKATIS 152 Query: 123 SHREAFA----GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFA 178 + A GV L+ T+ + R++ +L +L +E+G ++SA+ ++D L+ A Sbjct: 153 KGVNSTAFLVFMGVALSITAFPVLARILAELKLLTTEIGRLAMSAAAVNDVAAWILLALA 212 Query: 179 VG-SGS-----------LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMA 226 + SGS L G + I A FII I W S R E +E+ + Sbjct: 213 IALSGSNTSPLVSLWVFLSGCAFVIGASFIIPPIFRWIS----RRCHEGEPIEETYICAT 268 Query: 227 VGMMFLFAALAEGWFAAAIEGSFMMGLILSKL-PEGKRIMEEVRSIGYGLLIPIFFIHTG 285 + ++ + + + ++ G+F++G+++ K P ++E+V + GL +P++F+ +G Sbjct: 269 LAVVLVCGFITDAIGIHSMFGAFVVGVLIPKEGPFAGALVEKVEDLVSGLFLPLYFVASG 328 Query: 286 AMLNLTVFRNADAIKLALVLSTIAVIGKVAG 316 N+ + A + L ++++ A GK+ G Sbjct: 329 LKTNVATIQGAQSWGLLVLVTATACFGKILG 359 >pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp. (strain PCC 6803) >gi|1652066|dbj|BAA16991.1| (D90902) Na/H antiporter [Synechocystis sp.] Length = 410 Score = 100 bits (247), Expect = 3e-20 Identities = 99/412 (24%), Positives = 190/412 (46%), Gaps = 41/412 (9%) Query: 7 ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVS----KDYLPITMG 62 IL I V + LA++ + RF+ P V+GE+I G++LG + G++S K + P T Sbjct: 9 ILANIIVIIGLARLIGLLFARFQQPPVIGEIIAGIMLGPSL-LGLLSPALEKSFFPAT-- 65 Query: 63 SSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILG----YFALR 118 + + L+++G+IF +FL L+ + + L++ A +++ + +F P +LG +F L Sbjct: 66 TQPFLYLLSEIGLIFYMFLVGLELNPQYLRQKLKVAILTSNVSIFFPFVLGIVLSFFVLY 125 Query: 119 YMGYSHREAFAG-----GVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIA 173 + ++ +F G ++ T+ + R++ D G+ ++ +G L+ + +DD Sbjct: 126 SLNQPNKTSFIPFALFIGAAMSITAFPVLARILKDTGLDKTPLGTLGLTCASVDDISAWC 185 Query: 174 LIIFAVG---SGSLLG---LSMKIIAFFIITGILGWYSIDKYI--RFAERLHVEKGILGM 225 L+ A+ + ++ G + II + + LG KYI + ++ ++ +G+L Sbjct: 186 LLAIAIAVTRTDNIFGAFPTLLGIIVYTVFMVTLG-RKFFKYILRNYGQKNYLSQGLLTF 244 Query: 226 AVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLPE-GKRIMEEVRSIGYGLLIPIFFIHT 284 M+ L A L E I G F++G IL K + + L+PIFF ++ Sbjct: 245 IYIMVILSAMLTEWIGIDVIFGGFILGAILPKNTNLSTELATKTEDFVSTFLLPIFFAYS 304 Query: 285 GAMLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQ 344 G +L + + + V +AG+ G ++T G + ++ K Sbjct: 305 GLSTDLGLLNK----PYLWAVCALVVAAAIAGKYCGVYVTTRALGVE----KQEAK---A 353 Query: 345 MGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLL 396 +G R L+ L V + G ISP F+ I ++ +IT PL+ Sbjct: 354 LGWLMNTRGLTELIILNVGLKLGVISPVIFTMFV----IMAIITTIITSPLV 401 >pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abyssi (strain Orsay) >gi|5458640|emb|CAB50128.1| (AJ248286) Na+/H+ antiporter (napA-4) [Pyrococcus abyssi] Length = 390 Score = 100 bits (246), Expect = 4e-20 Identities = 92/409 (22%), Positives = 191/409 (46%), Gaps = 53/409 (12%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67 +F + + L++AK + ++++ + ++ ++ G++LG FG+ + SE + Sbjct: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGP---FGLA-------IVKPSEEL 53 Query: 68 DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127 L + G+I ++ L ++ + + + ATI +GV ILG+ + ++ + A Sbjct: 54 KVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAA 113 Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI--IFAVGSGS-- 183 G+ L T+I +T V++ V + E+ + + A+ DD + + LI + + GS Sbjct: 114 LFVGITLGNTAIEVTSGVLVRERV-KKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFS 172 Query: 184 ---LLGLSMKIIAFFIITGILGWYSIDKYIRF---AERLHVEKGILGMAVGMMFLFAALA 237 ++ L++KI+ F + T ++ + + RF + LHV + + F+ A LA Sbjct: 173 LYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHV---FFTFTIILTFMLAFLA 229 Query: 238 EGWFAAAIEGSFMMGLILSKLPEGK-----------RIMEEVRSIGYGLLIPIFFIHTGA 286 E I G+++ GL +S+L E K ++ E+ + IP+FFI+ G Sbjct: 230 EDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGL 289 Query: 287 MLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMG 346 M V R + +AL L A++GK+ G G G L + + ++ +G Sbjct: 290 MFQPNV-REISVLMIAL-LYLAAILGKLIGCGLG-----------MLLFGSSLRDAIIVG 336 Query: 347 IGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPL 395 +G R + L L + + G I+ + + AT++ +++ ++ P+ Sbjct: 337 VGMGGRGSLELAILKLGLEKGLIN-----ESLFATIVIVSMLTALSTPI 380 >pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1001647|dbj|BAA10378.1| (D64002) Na(+)/H(+) antiporter [Synechocystis sp.] Length = 698 Score = 99.5 bits (244), Expect = 7e-20 Identities = 94/406 (23%), Positives = 181/406 (44%), Gaps = 31/406 (7%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67 L + L++ I I ER +LPG++G L G++LG G++++D SE I Sbjct: 13 LIDFTILLLVTLILPPIFERLKLPGLVGLLFAGIVLGKSG-LGVLNED--------SESI 63 Query: 68 DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127 +G I+L+F+ L+ D+ ++T + + + VPL+ G GYS + Sbjct: 64 KLFTDIGKIYLMFVAGLEIDMVDFRRTRNRSLLYGSLTFAVPLLTGLAVGLTFGYSFNAS 123 Query: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAV----GSGS 183 G L + ++ L ++ LG++R++ ++ A++ D + ++ + GS S Sbjct: 124 VLLGSLFASHTL-LGYPIVQRLGIVRNQAVMVTIGATIFTDIAALLVLAICISIHSGSFS 182 Query: 184 LLGLSMKIIAFFIITGIL----GWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEG 239 GL ++++A + + ++ W + + R + + + +AV FL + +E Sbjct: 183 PAGLVVQLVAIAVYSALVLIGFDWAGREYFRRTGDEQSNQFLFVLLAV---FLASVGSEL 239 Query: 240 WFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI 299 I G+F+ GL ++ + + E+V +G L IP FFI G +L+L F Sbjct: 240 INVDKIVGAFLAGLAVNDVLGNSPVKEKVEFLGTTLFIPFFFIGIGLLLDLPAFLVTLTT 299 Query: 300 KLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVD 359 LV++ V+G + +G A + W G ++ L M SIP+ L Sbjct: 300 LFPLVVA--IVVGLILSKGVAAILAQWKLGYTWV-------EGLTMWSLSIPQVAATLAA 350 Query: 360 LMVAIHGGAISPDD-VPKFIAATLIFITVSVLITPPLLKWAFREEV 404 + + D V + + T+I + + I PL+ F ++ Sbjct: 351 AVAGYQAVNAAGDRLVSETVLNTIIVLMLITSIVGPLMTAKFAPKI 396 >pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii >gi|1591911|gb|AAB99281.1| (U67568) NA(+)/H(+) antiporter (napA) [Methanococcus jannaschii] Length = 388 Score = 99.1 bits (243), Expect = 9e-20 Identities = 95/408 (23%), Positives = 187/408 (45%), Gaps = 38/408 (9%) Query: 1 MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60 ME ++ F I L + I ++++F +P + +I G+++G +G+ + L + Sbjct: 1 MESYYYVFFII---LSIIFIVPNLLKKFNIPAITSIMIAGIIIGP---YGL---NILQV- 50 Query: 61 MGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM 120 E + LA G I L+FL L+ D E LK+ + I +L + +P + GY +Y+ Sbjct: 51 ---DETLKILADFGAIMLMFLAGLEVDNETLKQEFKNSLILSLFSLLIPGVGGYLIGQYL 107 Query: 121 GYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIAL--IIFA 178 G + V+ + S+ + ++ +L ++++ +G LSA+++ D + L ++ Sbjct: 108 GLGFIGSLLYAVIFASHSVAIVYAILEELKMVKTRLGTIILSATIIVDLFTLLLLSVVIK 167 Query: 179 VG-SGSLLGLSMKIIAFFIITGILGWYSIDKYI-RFAERLHVEKGILGMAVGMMFLFAAL 236 +G G +G + +I +L S+ K I E+LH ++ + + ++F+ + Sbjct: 168 LGIGGENVGTFLLETVLYIGVLLLAIPSLSKNILGVFEKLHAQR--IHYVLFIIFIAIIV 225 Query: 237 AEGWFAAAIEGSFMMGL----ILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTV 292 E I G+F+ G+ L+K + + + + +IGYG IPIFF+ G N+ V Sbjct: 226 GEVIGIHPIVGAFICGVAVSEALTKEEHDELLNKNLNAIGYGFFIPIFFLVLGMETNIRV 285 Query: 293 FRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPR 352 N ++L L+ AV K I + R ++ + G+ ++P+ Sbjct: 286 IFNLSNLELLLITLISAVALKFISGFIALRILGFDRIKNTI-----------GGLLTVPK 334 Query: 353 TEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAF 400 +LV + G I + +A ++I T ITP ++K F Sbjct: 335 ISASLVAASIGRELGLIGNEIFVTIVALSVITAT----ITPIVVKHIF 378 >pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thaliana >gi|4454039|emb|CAA23036.1| (AL035394) putative Na+/H+-exchanging protein [Arabidopsis thaliana] >gi|7269218|emb|CAB79325.1| (AL161559) putative Na+/H+-exchanging protein [Arabidopsis thaliana] Length = 820 Score = 99.1 bits (243), Expect = 9e-20 Identities = 89/332 (26%), Positives = 157/332 (46%), Gaps = 28/332 (8%) Query: 7 ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEV 66 ++ I + L+L ++ ++ P V+ E++ G+LLG S V Sbjct: 33 LILQICIVLLLTRLLAFLLRPLRQPRVIAEIVGGILLGPSALGKSTKFINTVFPPKSLTV 92 Query: 67 IDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGY---FALRYM--- 120 +D LA LG+IF LFL L+ D + LK+TG A L G+ +P +LG FALR Sbjct: 93 LDTLANLGLIFFLFLVGLELDPKSLKRTGKRALSIALAGITLPFVLGIGTSFALRSSIAD 152 Query: 121 GYSHREAFA-GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAV 179 G S GV L+ T+ + R++ ++ +L +++G +LSA+ ++D L+ AV Sbjct: 153 GASKAPFLVFMGVALSITAFPVLARILAEIKLLTTDIGKIALSAAAVNDVAAWILLALAV 212 Query: 180 ---GSGS---------LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAV 227 G GS L G + F++ G I K R E V + + + Sbjct: 213 ALSGEGSSPLTSLWVFLSGCGFVLFCIFVVQP--GIKLIAK--RCPEGEPVNELYVCCTL 268 Query: 228 GMMFLFAALAEGWFAAAIEGSFMMGLILSKLPEG---KRIMEEVRSIGYGLLIPIFFIHT 284 G++ + + + A+ G+F++G+I K EG ++E+V + GL +P++F+ + Sbjct: 269 GIVLAASFVTDFIGIHALFGAFVIGVIFPK--EGNFANALVEKVEDLVSGLFLPLYFVSS 326 Query: 285 GAMLNLTVFRNADAIKLALVLSTIAVIGKVAG 316 G N+ + A + L +++ A GK+ G Sbjct: 327 GLKTNVATIQGAQSWGLLVLVIFNACFGKIIG 358 >pir||C82955 probable sodium/proton antiporter PA5529 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951867|gb|AAG08914.1|AE004965_6 (AE004965) probable sodium/proton antiporter [Pseudomonas aeruginosa] Length = 585 Score = 99.1 bits (243), Expect = 9e-20 Identities = 87/401 (21%), Positives = 186/401 (45%), Gaps = 42/401 (10%) Query: 11 IGVALILAKIGDAIIERFELPGVLGELIMGMLLG-NLVYFGIVSKDYLPITMGSSEVIDF 69 + V +++A + + R P VLG ++ G ++G + FG++ + + I Sbjct: 10 LAVIMLVAGVVTILFHRLRQPVVLGYIVAGFIIGPHTPPFGLIHDE---------DTIKT 60 Query: 70 LAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFA 129 LA+LG+IFL+F L+ + +L + G TA I+ + + + + +G+ R+ +S ++ Sbjct: 61 LAELGVIFLMFCLGLEFSLRKLFQVGATAFIAAFLEIVLMIWIGFEIGRFFEWSTMDSLF 120 Query: 130 GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIF--------AVGS 181 G +L +S + V+ + DL + +++D LGI +I +V + Sbjct: 121 LGAILAISSTTIIVKALGDLKMKNERFAQLIFGVLIVEDILGIGIIALLSGIAVSGSVET 180 Query: 182 GSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWF 241 G + K+ F I+ ++G + + + + + + +L +G+ F F L Sbjct: 181 GEVFSTVGKLSLFMIVALVVGILLVPRLLAYVAKFESNEMLLVTVLGLCFGFCLLVVKLE 240 Query: 242 AAAIEGSFMMGLILS---KLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADA 298 + + G+F++G I++ +L + +R++E VR + IFF+ G +++ + A Sbjct: 241 YSMVLGAFLIGAIMAESRQLVQIERLIEPVRD----MFSAIFFVAIGLLIDPKILVEY-A 295 Query: 299 IKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALV 358 +AL+ + V+GK+ G GA+I + + SL++G+G E + + Sbjct: 296 WPIALI-TVAVVLGKMFSCGMGAFIAG-----------NDGRTSLRVGMGLSQIGEFSFI 343 Query: 359 DLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWA 399 + + S P +A + ++ L+TP L++ A Sbjct: 344 IAALGMTLKVTSDFLYPVAVAVS----AITTLLTPYLIRAA 380 >gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum] Length = 713 Score = 98.7 bits (242), Expect = 1e-19 Identities = 99/432 (22%), Positives = 192/432 (43%), Gaps = 35/432 (8%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITM--GSSE 65 L T+ + L+ A+ + R P VLGEL G++LG V + + + Sbjct: 13 LVTLALILVTARASGELARRLRQPEVLGELFGGVVLGPSVVGALAPGFHRALFQEPAVGV 72 Query: 66 VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILG-YFALRYMGYSH 124 V+ ++ +G + LL + ++ DV L+K +S L + PL G F+ + Sbjct: 73 VLSGISWIGALLLLLMAGIEVDVGILRKEARPGALSALGAIAPPLAAGAAFSALVLDRPL 132 Query: 125 REAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD---FLGIALIIFAVGS 181 G++L+ T++ + +V+++ +R +L+A V+ + ++ +A+ + G+ Sbjct: 133 PSGLFLGIVLSVTAVSVIAKVLIERESMRRSYAQVTLAAGVVSEVAAWVLVAMTSSSYGA 192 Query: 182 GSLLGLSMKII---AFFIITGILGWYSIDKYIRF-AERLHVEKGILGMAVGMMFLFAALA 237 L ++ + F + ++G +R+ A+ V KG + + + + FL AAL Sbjct: 193 SPALAVARSALLASGFLLFMVLVGRRLTHLAMRWVADATRVSKGQVSLVLVLTFLAAALT 252 Query: 238 EGWFAAAIEGSFMMGLILSKLPEGKR-IMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNA 296 + + G+F +G++L+ P R +++ V+++ GL P+FF+ G ++++ R Sbjct: 253 QRLGLHPLLGAFALGVLLNSAPRTNRPLLDGVQTLVAGLFAPVFFVLAGMRVDVSQLRTP 312 Query: 297 DAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVA 356 A +L A KV GA + RG + + L M G+ Sbjct: 313 AAWGTVALLLATATAAKVVPAALGARLGGL-RGSEAALV----AVGLNMKGGT------- 360 Query: 357 LVDLMVAIHG---GAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQRKARIE 413 DL+VAI G G +S + + L+ +T S P LL W + Q ++ Sbjct: 361 --DLIVAIVGVELGLLSNEAYTMYAVVALVTVTAS----PALLIWLEKRAPPTQEES--- 411 Query: 414 SRKERIEKKKKA 425 +R ER E ++A Sbjct: 412 ARLEREEAARRA 423 >pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis >gi|2633518|emb|CAB13021.1| (Z99110) similar to Na+/H+ antiporter [Bacillus subtilis] Length = 614 Score = 98.3 bits (241), Expect = 2e-19 Identities = 80/325 (24%), Positives = 157/325 (47%), Gaps = 35/325 (10%) Query: 13 VALILAKIGDAIIERFEL--PGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFL 70 V LI+A + ++ RF+L P V+ E+IMG+++G K L + + + L Sbjct: 11 VVLIVAFLTPILLHRFKLSIPVVVAEIIMGLIIG---------KSGLNLVVEGDTWLQTL 61 Query: 71 AKLGIIFLLFLGALDTDVEQLKK--------------TGLTATISTLMGVFVPLILGYFA 116 + LG IFL+FL L+ D +K A +G+F+ +L + Sbjct: 62 SMLGFIFLMFLSGLEIDFSSFEKGKKKQFLPNGKEAPNTFAAASVIFVGIFILSLLLSYG 121 Query: 117 LRYMGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI- 175 G+ + AF ++++ S+G+ V + + ++ S +G L +V+ D + L+ Sbjct: 122 FVLAGFI-QNAFLMTLIISTISLGVVVPTLKEERIMNSNIGQIILLVAVIADLATMILLA 180 Query: 176 IFAVGSGSLLGLSMKIIAFFIITGILGWYS-IDKYIRFAERLHVEKGILGMAVGMMF--- 231 +F+ G G ++ F +L ++ + K+ F + + KG + + +F Sbjct: 181 VFSSLYGEDSGNMWLLMILFAAGVVLYFFGRVFKHRSFVQSM--SKGTIQIGTRAIFTLI 238 Query: 232 -LFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNL 290 + AL+E A I G+F+ G+++S L K +++++ S GYG LIPIFF+ G L++ Sbjct: 239 IVLVALSESLGAENILGAFLAGVLVSLLSPNKELVQQLDSFGYGFLIPIFFVMVGVKLDI 298 Query: 291 -TVFRNADAIKLALVLSTIAVIGKV 314 T+F++ + + +L ++ K+ Sbjct: 299 WTLFQDKTILIMIPLLLLALLVSKI 323 >emb|CAB45049.1| (AL078635) putative integral membrane ion antiporter [Amycolatopsis orientalis] Length = 409 Score = 97.9 bits (240), Expect = 2e-19 Identities = 83/328 (25%), Positives = 152/328 (46%), Gaps = 18/328 (5%) Query: 6 WILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSE 65 ++L + V ++LA++ A+ R + P V+GEL+ G+LLG ++ + P + Sbjct: 8 FLLLDLAVIVVLARLLGAVARRLDQPPVIGELLAGILLGPTLFGEGFAAALFPTDV--RP 65 Query: 66 VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYS-- 123 + LA +G+ +F+ L+ + L+ G A ++ + +P LG Y+ + Sbjct: 66 FLAALANVGVAMFMFMVGLELEQTLLRGRGKLALTVSVSSIVLPFTLGVGLAFYLAMNRP 125 Query: 124 --HREAFA--GGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI-IFA 178 HR F G ++ T+ + R++ D G+LR+ +G +L+ + + D L L+ + Sbjct: 126 VEHRLGFLLFIGAAMSVTAFPVLARILQDRGMLRTMLGGLALTCAAIGDVLAWCLLAVVV 185 Query: 179 VGSGSLLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAE 238 + SG G +I I L + + +R V G L + + A+ E Sbjct: 186 IVSGGASGTEQWLIVLGPIYVALMLWVVRPLLRKLFTAGV-TGALPTVLAGALISGAVTE 244 Query: 239 GWFAAAIEGSFMMGLILSKLPEG-----KRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVF 293 I G+F+ G+I+ + EG RI++ V LL+P+FFI +G +NL+ Sbjct: 245 LIGLHFIFGAFLFGVIVPR--EGTDTLRHRIIDRVEEFNSALLLPVFFIVSGLKVNLSTL 302 Query: 294 RNADAIKLALVLSTIAVIGKVAGRGFGA 321 ++ LVL +A+ GK G GA Sbjct: 303 SATGLVEFGLVL-LVAIAGKFGGAFVGA 329 >dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arabidopsis thaliana] Length = 800 Score = 91.7 bits (224), Expect = 1e-17 Identities = 78/328 (23%), Positives = 164/328 (49%), Gaps = 20/328 (6%) Query: 7 ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG--SS 64 I+ I + ++ ++ ++ + P V+ E+I G+LLG SK YL S Sbjct: 35 IILQIVLVVVFTRLLAYFLKPLKQPRVIAEIIGGILLGPSALGR--SKAYLDTIFPKKSL 92 Query: 65 EVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSH 124 V+D LA +G++F LFL L+ D +KKTG + + + G+ +P I+G + + Sbjct: 93 TVLDTLANIGLLFFLFLVGLELDFAAIKKTGKKSLLIAIAGISLPFIVGVGTSFVLSATI 152 Query: 125 REAFAG-------GVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD---FLGIAL 174 + GV L+ T+ + R++ +L +L +++G ++SA+ ++D ++ +AL Sbjct: 153 SKGVDQLPFIVFMGVALSITAFPVLARILAELKLLTTDIGRMAMSAAGVNDVAAWILLAL 212 Query: 175 IIFAVGSGSLLGLSMKII---AFFIITGILGWYSIDKYI--RFAERLHVEKGILGMAVGM 229 I G G+ +S+ ++ F+I ++ + Y+ R E V++ + + + + Sbjct: 213 AIALSGDGTSPLVSVWVLLCGTGFVIFAVVAIKPLLAYMARRCPEGEPVKELYVCVTLTV 272 Query: 230 MFLFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIM-EEVRSIGYGLLIPIFFIHTGAML 288 + + + + A+ G+F++G++ K RI+ E++ + GLL+P++F +G Sbjct: 273 VLAASFVTDTIGIHALFGAFVVGIVAPKEGPFCRILTEKIEDLVSGLLLPLYFAASGLKT 332 Query: 289 NLTVFRNADAIKLALVLSTIAVIGKVAG 316 ++T R A + L +++ GK+ G Sbjct: 333 DVTTIRGAQSWGLLVLVILTTCFGKIVG 360 >gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana] Length = 868 Score = 91.3 bits (223), Expect = 2e-17 Identities = 82/303 (27%), Positives = 142/303 (46%), Gaps = 35/303 (11%) Query: 40 GMLLGNLVYFGIVSKDYLPITMGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTAT 99 G+LLG I S S V+D LA LG++ LFL L+ D+ L++TG A Sbjct: 132 GILLGPSALGRITSYKNSIFPARSLTVLDTLANLGLLLFLFLVGLEIDLTSLRRTGKKAI 191 Query: 100 ISTLMGVFVPLILGYFALRYMGYSHREAFAGG-------------VLLTATSIGLTVRVM 146 G+ +P +G ++ EA + G V L+ T+ G+ R++ Sbjct: 192 SIAAAGMLLPFGMGIVT----SFAFPEASSSGDNSKVLPFIIFMGVALSITAFGVLARIL 247 Query: 147 MDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG-SGSL------LGLSMKIIAFFIITG 199 +L +L +++G S++A+ ++D L+ AV SG L + + IAF I Sbjct: 248 AELKLLTTDLGRISMNAAAINDVAAWVLLALAVSLSGDRNSPLVPLWVLLSGIAFVIACF 307 Query: 200 ILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAAAIE-----GSFMMGLI 254 ++ + + +F R E +G + L A L G+ AI G+F+MG++ Sbjct: 308 LI----VPRIFKFISRRCPEGEPIGEMYVCVALCAVLLAGFATDAIGIHAIFGAFVMGVL 363 Query: 255 LSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAI-KLALVLSTIAVIGK 313 K I+E++ + GLL+P++F+ +G ++T + + +LALV+ T A GK Sbjct: 364 FPKGHFSDAIVEKIEDLVMGLLLPLYFVMSGLKTDITTIQGVKSWGRLALVIVT-ACFGK 422 Query: 314 VAG 316 + G Sbjct: 423 IVG 425 >dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans] Length = 686 Score = 90.9 bits (222), Expect = 3e-17 Identities = 88/421 (20%), Positives = 194/421 (45%), Gaps = 46/421 (10%) Query: 3 PATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG 62 P T + +A+++ + ++ R +PG++G ++ G+++G F ++ +D + +G Sbjct: 5 PITDPVLIFAIAMVVFFVAPLLMSRLRIPGIIGLILAGVVIGPNG-FALLDRDPTIVLLG 63 Query: 63 SSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGY 122 + +G+++++F+ L+ D+E KK + + + +P + G +G+ Sbjct: 64 T---------VGLLYIIFIAGLEIDLEGFKKYRNRSVLFGTLSFTIPFLFGLVFTFILGF 114 Query: 123 SHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSG 182 S A +L + ++ L + LG+ + ++ ++M D L AL++ A+ +G Sbjct: 115 STPAAILLASILGSHTL-LAYPIASRLGISKDRGVTTAVGGTIMTDTL--ALLVLAIVAG 171 Query: 183 SLLG---------LSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLF 233 S+ G +++ ++ + IT IL I + R +G L M LF Sbjct: 172 SMQGELNSTFWFTIAVSLVLYVAITLIL----IPILAKSFFRTMSSEGALEFIFVMSILF 227 Query: 234 AALAEGWFAAAIE---GSFMMGLILSK-LPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLN 289 A G A +E G+F+ GL L++ + E +M ++ +G L IP F + G +++ Sbjct: 228 VT-AYGATLAGLEPIIGAFLAGLALNRFILEHSPLMNRIKFVGNALFIPFFLLSVGMLMD 286 Query: 290 LTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGS 349 + V + A +L+ + VI G+ A+I+ G+ + ++ + K+ + S Sbjct: 287 IRVLLGDPS---AWLLAALVVIFVQLGKFLAAFIS----GKLYNYSMDQIKLMFGL---S 336 Query: 350 IPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLL-KWAFREEVEAQR 408 +P+ L +V G + A ++ I V+ ++ P ++ K+A + +E + Sbjct: 337 VPQAAATLAATLVGFDLGLFD----SAVVNAVIVMILVTCMVGPYVVEKYARKLALEEEL 392 Query: 409 K 409 K Sbjct: 393 K 393 >gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter [Arabidopsis thaliana] Length = 821 Score = 90.5 bits (221), Expect = 3e-17 Identities = 88/390 (22%), Positives = 169/390 (42%), Gaps = 40/390 (10%) Query: 24 IIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFLAKLGIIFLLFLGA 83 I++ F P V+ E++ G++LG V + S V++ +A +G+++ LFL Sbjct: 57 ILKPFRQPRVISEILGGIVLGPSVLGRSTKFAHTIFPQRSVMVLETMANVGLLYFLFLVG 116 Query: 84 LDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFAG------GVLLTAT 137 ++ D+ ++KTG A + G+ +P ++G M S G GV L+ T Sbjct: 117 VEMDIMVVRKTGKRALTIAIGGMVLPFLIGAAFSFSMHRSEDHLGQGTYILFLGVALSVT 176 Query: 138 SIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSG-----SLLGLSMKI- 191 + + R++ +L ++ +E+G S+SA++++D L+ A+ S L + I Sbjct: 177 AFPVLARILAELKLINTEIGRISMSAALVNDMFAWILLALAIALAESDKTSFASLWVMIS 236 Query: 192 ------IAFFIITGILGWY--SIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAA 243 + F++ + W + F+E H+ + G+ + A F Sbjct: 237 SAVFIAVCVFVVRPGIAWIIRKTPEGENFSE-FHICLILTGVMISGFITDAIGTHSVF-- 293 Query: 244 AIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLAL 303 G+F+ GL++ P G ++E++ GLL+P+FF +G N+ + Sbjct: 294 ---GAFVFGLVIPNGPLGLTLIEKLEDFVSGLLLPLFFAISGLKTNIAAIQGPATWLTLF 350 Query: 304 VLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVA 363 ++ +A GKV G I A+ G + RE + L + LV+++V Sbjct: 351 LVIFLACAGKV----IGTVIVAFFHG---MPVREGITLGLLL-------NTKGLVEMIVL 396 Query: 364 IHGGAISPDDVPKFIAATLIFITVSVLITP 393 G D F L+ + ++ +ITP Sbjct: 397 NVGKDQKVLDDETFATMVLVALVMTGVITP 426 >pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spirochete >gi|2688368|gb|AAC66821.1| (AE001150) Na+/H+ antiporter (napA) [Borrelia burgdorferi] Length = 701 Score = 88.9 bits (217), Expect = 1e-16 Identities = 92/420 (21%), Positives = 184/420 (42%), Gaps = 43/420 (10%) Query: 1 MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60 M A ++ +I + ++AKIG +P V+G++ G++L + I P+ Sbjct: 36 MSLAIIVISSISIGNLVAKIG--------IPKVIGQITAGIILSPNAFGKIQIPLLFPLG 87 Query: 61 MGS-------SEVIDFLAKLGIIFLLFLGALDTDVEQLKK---TGLTATISTLMGVFVPL 110 + +E I ++ + I LLF L+TD++ K G I+ ++G F Sbjct: 88 ITQIGENYLINEKIFAISTIASIILLFTAGLETDLKLFIKFLPRGGIIGITEVVGTFTSF 147 Query: 111 ILGYFALRYMGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFL 170 +L + + + G++ T TS G+ ++ + + G +S S++DD L Sbjct: 148 VLMASIIFNVPLISPTSLFIGIIGTPTSAGIAASILSAKKKMSTSEGVTIISTSIIDDVL 207 Query: 171 GIALIIFAVG-SGSLLGLSMKIIAFFIITGILGW--------YSIDKYIRFAERLHVEKG 221 + ++ + S S+ L + I+ I+ W Y + R ++L+ Sbjct: 208 SMLMLTSVITISRSISDLDIASSIKAIVQNIVIWLCLTFSLIYISETLSRLLKKLNSVTL 267 Query: 222 ILGMAVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFF 281 + + + A++ + + + G+++ GL +SK + ++++ +I IPIFF Sbjct: 268 ATVITLSLALTIASIFQNLGMSFVVGAYVFGLAMSKT-DIVYVIQDKLTIFERFFIPIFF 326 Query: 282 IHTGAMLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKM 341 G M ++ + + + L L +S IA+I K +I A LF N Sbjct: 327 TSIGLMSDINEILSKEVLILGLAISAIAIITK----SIFCFIPA-------LFLGFNKLG 375 Query: 342 SLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFR 401 +L++ G +PR EV+L+ VA+ G IS K +I + + +I P++ + F+ Sbjct: 376 ALKIATGMVPRGEVSLIMANVALSSGFIS----QKIFGIIIIMVFLPTIIATPIINFLFK 431 >pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana >gi|7629992|emb|CAB88334.1| (AL132960) putative protein [Arabidopsis thaliana] Length = 842 Score = 88.2 bits (215), Expect = 2e-16 Identities = 78/345 (22%), Positives = 162/345 (46%), Gaps = 43/345 (12%) Query: 8 LFTIGVALILA--KIGDAIIERFELPGVLGELIMGMLLG------NLVYFGIVSKDYLPI 59 L + ALI+A + + + P V+ E++ G+LLG N+ Y + + Sbjct: 28 LLIVQTALIIAVSRFLAVLFKPLRQPKVIAEIVGGILLGPSALGRNMAYMDRIFPKW--- 84 Query: 60 TMGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILG------ 113 S +++ +A +G++F LFL L+ D+ ++++G A + G+ +P I G Sbjct: 85 ---SMPILESVASIGLLFFLFLVGLELDLSSIRRSGKRAFGIAVAGITLPFIAGVGVAFV 141 Query: 114 -----YFALRYMGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD 168 Y A GY+ F GV L+ T+ + R++ +L +L +++G +++A+ +D Sbjct: 142 IRNTLYTAADKPGYAEFLVFM-GVALSITAFPVLARILAELKLLTTQIGETAMAAAAFND 200 Query: 169 ---FLGIALIIFAVGSGSLLGLSMK--IIAFFIITGILGWYSIDKYI------RFAERLH 217 ++ +AL + G+G G K +++ +++ G+ + A+R Sbjct: 201 VAAWILLALAVALAGNGGEGGGEKKSPLVSLWVLLSGAGFVVFMLVVIRPGMKWVAKRGS 260 Query: 218 VEKGILGMAVGMMFLFAALAEGWFA-----AAIEGSFMMGLILSKLPE-GKRIMEEVRSI 271 E ++ + + L + G+ +I G+F+ GL + K E G+R++E + Sbjct: 261 PENDVVRESYVCLTLAGVMVSGFATDLIGIHSIFGAFVFGLTIPKDGEFGQRLIERIEDF 320 Query: 272 GYGLLIPIFFIHTGAMLNLTVFRNADAIKLALVLSTIAVIGKVAG 316 GLL+P++F +G ++ R A++ + ++ A GK+ G Sbjct: 321 VSGLLLPLYFATSGLKTDVAKIRGAESWGMLGLVVVTACAGKIVG 365 >gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus] Length = 505 Score = 85.8 bits (209), Expect = 9e-16 Identities = 75/309 (24%), Positives = 144/309 (46%), Gaps = 21/309 (6%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67 L +G+ LI AKI + I R L +G ++MG+LLGN V FG++ +E+I Sbjct: 9 LLYLGIMLIAAKISEEIFRRIGLVTFVGPILMGILLGNGV-FGVIQ---------INEII 58 Query: 68 DFLAKLGIIFLLFL-GALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHRE 126 F+ LGI+FLLFL GA + +VE + ++ ++ +P + A+ +G+ + Sbjct: 59 SFITSLGIVFLLFLAGAEEFNVE--NRPNANVFLAVILESIIPFSVILVAIYIIGFKNYL 116 Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGSLLG 186 V L +S G R++MD+ + + + ++ + + + L + + +L Sbjct: 117 ILI--VPLAMSSAGPLSRMLMDVKISDNRISNLIFQQVILIEIIFVILFAILLKTSEILI 174 Query: 187 LSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGI-LGMAVGMMFLFAALAEGW-FAAA 244 ++I F T + G ++ K + E + I + ++ + LAE + F +A Sbjct: 175 TIIEIFLVFAFTIMFG-RTLAKILEKIEYYFKAREIEFASLIAIILIIGYLAELYKFNSA 233 Query: 245 IEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLALV 304 I F+ L+ L + ++E + + YG P+FF+ G + NA I +L+ Sbjct: 234 ISAFFLGILLKDYLKDRPELLERLHAFTYGFFEPLFFLGIGLYVTKI---NASIILFSLL 290 Query: 305 LSTIAVIGK 313 ++ + K Sbjct: 291 FFSLIIASK 299 >pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis >gi|2226151|emb|CAA74453.1| (Y14080) hypothetical protein [Bacillus subtilis] >gi|2633321|emb|CAB12825.1| (Z99109) similar to Na+/H+ antiporter [Bacillus subtilis] Length = 408 Score = 85.4 bits (208), Expect = 1e-15 Identities = 97/415 (23%), Positives = 178/415 (42%), Gaps = 57/415 (13%) Query: 1 MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLG-NLVYFGIVSKDYLPI 59 M P ++F +G AL+L I I + + + +++GML+G + GI+ ++ Sbjct: 1 MSPMDHLVFEVGTALVLVAIASVIANKIKFSIIPFLIVLGMLVGPHAPKMGIIDLTFIQ- 59 Query: 60 TMGSSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRY 119 SSE+I+F ++G++FLLF L+ V +L K+G + + + + + LG Sbjct: 60 ---SSEIIEFFGRMGVLFLLFYLGLEFSVGKLIKSGKSIAVGGTIYILINFSLGLLYGFI 116 Query: 120 MGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDD-FLGIALIIFA 178 G+S E ++T +S + +V++DL + L + +D FL + L + Sbjct: 117 TGFSFLEVLILAGVITISSSAIVAKVLVDLKRTANPETELILGIIMFEDIFLAVYL---S 173 Query: 179 VGSGSLLG---------LSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGM 229 V SG +LG LS+ I +++ + + + + + + + Sbjct: 174 VVSGLILGDATSVGSALLSILIAFGYMLLFFIAARKLPPLLNKLLDIRSNEVFIIVIFAA 233 Query: 230 MFLFAALAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIP-------IFFI 282 +F A +E A G+ ++GL+ S+ RI L++P +FF Sbjct: 234 LFFIAGFSETIHVAEAIGALLLGLVFSETEHSDRIEH--------LVVPFRDFFGAMFFF 285 Query: 283 HTGAMLNLTVFRNADAIKLAL--VLSTIA---VIGKVAGRGFGAWITAWGRGRDFLFTRE 337 G L++ F +A+ LAL V+ TI + G VAGR G Sbjct: 286 SFG--LSIDPFSLGEAVWLALGAVILTILGNFIAGMVAGRRAGL---------------- 327 Query: 338 NFKMSLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLIT 392 + K S +G+ + R E +++ + I GG +S P LI + L+T Sbjct: 328 SHKASSNIGLTIVSRGEFSIIVANLGIAGG-LSATLKPFAALYVLILAILGPLVT 381 >pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus >gi|2983090|gb|AAC06696.1| (AE000689) NA(+)/H(+) antiporter [Aquifex aeolicus] Length = 387 Score = 83.9 bits (204), Expect = 3e-15 Identities = 83/318 (26%), Positives = 142/318 (44%), Gaps = 42/318 (13%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67 L + ++ LA + I+ +P +GELI G+L+GN + GI +P E++ Sbjct: 13 LIIVFLSAFLAPLFSRILR---MPVPVGELIFGILIGNF-FVGI----QVP------EIL 58 Query: 68 DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYM-GYSHRE 126 +FL+ G + L+FL L+ D ++K V++ +L F ++ G Sbjct: 59 NFLSDFGFLLLMFLAGLELDFNLIEKADKKQN-----AVYISYVLLIFLSAFVFGILLGI 113 Query: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAV------G 180 A ++L+ S+GL V + D+ VL L V + + + + G Sbjct: 114 GTAPAIILSLISLGLMVATLKDMSVLEEPFAKKVLLIGVFGEIISLLALTLMEKLLHFHG 173 Query: 181 SGSLLGLSMKIIAFFI-------ITGILGWYSIDKYIRFAERLHVEK--GILGMAVGMMF 231 SL+ I FF +T +L W+ Y RL E+ LG+ + + Sbjct: 174 FVSLIKELGVIFVFFFSFFLGFYLTRLLVWW----YPEIVNRLTYEEDPSALGIRLSLFL 229 Query: 232 LFAALAEGWFAA--AIEGSFMMGLILSK-LPEGKRIMEEVRSIGYGLLIPIFFIHTGAML 288 +F + A ++ G+FM G++ S + E K + E++ SIGYG LIPIFFI TG + Sbjct: 230 MFTSSIFAKLAGIESVLGAFMAGVVFSYFIREKKDLEEKLSSIGYGFLIPIFFIKTGMGM 289 Query: 289 NLTVFRNADAIKLALVLS 306 + A K+ + L+ Sbjct: 290 EVAGLNLAILFKVFIFLA 307 >gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40309|YJJ4_YEAST HYPOTHETICAL 97.1 KD PROTEIN IN BCK1-TOK1 INTERGENIC REGION >gi|630170|pir||S46584 probable membrane protein YJL094c - yeast (Saccharomyces cerevisiae) >gi|521094|emb|CAA54359.1| (X77087) 12 transmembrane domains; J0909 ORF [Saccharomyces cerevisiae] >gi|1008268|emb|CAA89387.1| (Z49369) ORF YJL094c [Saccharomyces cerevisiae] Length = 873 Score = 78.8 bits (191), Expect = 1e-13 Identities = 96/425 (22%), Positives = 173/425 (40%), Gaps = 45/425 (10%) Query: 3 PATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG 62 P T LF + L++ + P V+ E+I G++LG ++ I + Sbjct: 22 PLTLFLFQACLILLVCNLIHIPFSMMRQPKVISEVISGVILGPTIFGQIPNYTNTIFPTS 81 Query: 63 SSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILG--------- 113 S ++ +A LGII +F L+ D+ +KK A + ++ + VP G Sbjct: 82 SIPGLNLVANLGIILFMFFLGLEVDIAFIKKHLKKALVIGIVTLAVPFGFGCLLAIPLFH 141 Query: 114 YFALRYMGYSHREAFAGGVLLTATSIGLTV-----RVMMDLGVLRSEVGAASLSASVMDD 168 +A + G H + F+ ++ A SI +T R++ +L +++ G L+A +++D Sbjct: 142 TYANKTEGERHIK-FSVFMVFIAVSISVTAFPVLCRILNELRLIKDRAGIVVLAAGIIND 200 Query: 169 FLGIALIIFAVGSGSLLGLSMKIIAFFIITGILGWYSID----KYIR--FAERLH-VEKG 221 +G L+ ++ S G + + +IT W+ I KY+ R H +++ Sbjct: 201 IMGWILLALSIILSSAEGSPVNTVYILLIT--FAWFLIYFFPLKYLLRWVLIRTHELDRS 258 Query: 222 ILGMAVGMMFLFAALAEGWFAAAIE-----GSFMMGLILSKLPE-GKRIMEEVRSIGYGL 275 M LF +F I G+F+ GL++ + ++ E + I + Sbjct: 259 KPSPLATMCILFIMFISAYFTDIIGVHPIFGAFIAGLVVPRDDHYVVKLTERMEDIPNIV 318 Query: 276 LIPIFFIHTGAMLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFT 335 IPI+F G ++LT+ IA+ K+ A +T LF Sbjct: 319 FIPIYFAVAGLNVDLTLLNEGRDWGYVFATIGIAIFTKIISGTLTAKLTG-------LFW 371 Query: 336 RENFKMSLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPL 395 RE + M I V +V L V ++ G IS K ++ VS +T PL Sbjct: 372 REATAAGVLMSCKGI----VEIVVLTVGLNAGIIS----RKIFGMFVLMALVSTFVTTPL 423 Query: 396 LKWAF 400 + + Sbjct: 424 TQLVY 428 >pir||F69201 conserved hypothetical protein MTH760 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621849|gb|AAB85263.1| (AE000854) Na+/H+-exchanging protein:Na+/H+ antiporter [Methanobacterium thermoautotrophicum] Length = 399 Score = 75.7 bits (183), Expect = 1e-12 Identities = 99/426 (23%), Positives = 190/426 (44%), Gaps = 54/426 (12%) Query: 6 WILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSE 65 ++ F++ V ++L + + + R LPG+LG LI+G+L+G ++SK + I+ Sbjct: 3 YVAFSVAVIILLGLLFNRVFTRARLPGILGMLILGILIGP-HGLNLISKSIMDISPD--- 58 Query: 66 VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTAT-ISTLMGVFVPLILGYFALRYMGYSH 124 L + +I +L ++E L+K G+TA +S + VF L + + +G Sbjct: 59 ----LRVIALIIILLRAGFGINLESLRKVGMTAVKMSFIPDVFEGLAVMVASHYILGLPI 114 Query: 125 REAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAAS------LSASVMDDFLGIAL--II 176 EA G ++ A S + V M L + +G A L+ + +DD + I L + Sbjct: 115 IEAGILGFVIAAVSPAVIVPQM--LSFIERRMGTAKGIPTIILTGASVDDVVSITLFSVF 172 Query: 177 FAVGSGSLLGLSMKIIA--FFIITGILGWYSIDKYI----RFAERLHVEKG--ILGMAVG 228 + G + L ++ I I+TGI G ++ + R E + EK ILG A+ Sbjct: 173 LGIYQGQQVNLLVEAIGVPLSILTGITGGLALGLALVYLFRRFEIRNTEKTLIILGAAIL 232 Query: 229 MMFLFAALAEGWFAAAIEGSFMMGL-ILSKLPE-GKRIMEEVRSIGYGLLIPIFFIHTGA 286 + + ++ AA+ G ++GL IL ++PE G ++ E+ + I + F+ GA Sbjct: 233 LKNMGDLISTYLPIAALVGVMVVGLVILERMPETGLKLSEKFNKVWIFAEI-LLFVLVGA 291 Query: 287 MLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMG 346 +++ + + + LA++ + + V R G ++ +G D + F +S Sbjct: 292 QVDVRLIFHVGLLGLAVITAGLMV------RSIGVLLSL--KGTDLNLKEKVFCIS---- 339 Query: 347 IGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPL----LKWAFRE 402 IP+ V + + G + + + L +++L T PL +KW Sbjct: 340 -AYIPKATVQAAIGAIPLAAGVAAGETI-------LAMAVLAILFTAPLGSLAVKWTGER 391 Query: 403 EVEAQR 408 +E +R Sbjct: 392 FLEVER 397 >gb|AAD30610.1|AC007153_2 (AC007153) similar to Na/H antiporter proteins [Arabidopsis thaliana] Length = 855 Score = 74.1 bits (179), Expect = 3e-12 Identities = 96/407 (23%), Positives = 175/407 (42%), Gaps = 42/407 (10%) Query: 30 LPGVLGELIMGML-----LGNLVYFGIVSKDYLPITMGSSEVIDFLAKLGIIFLLFLGAL 84 LP + +++ G+L LGN F I TM V++ A L +++ +FL L Sbjct: 77 LPPFVAQILCGLLFSPSVLGN-TRFIIAHVFPYRFTM----VLETFANLALVYNIFLLGL 131 Query: 85 DTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFAGGVLLTATSIGLT-- 142 D+ ++ T L I G+ V L +G F G H + G + + ++ T Sbjct: 132 GMDLRMVRITELKPVIIAFTGLLVALPVGAFLYYLPGNGHPDKIISGCVFWSVALACTNF 191 Query: 143 ---VRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGSLLGLSMKIIAFFIITG 199 R++ DL +LRS++G ++ A+++ D L++F S S G K++ F IIT Sbjct: 192 PDLARILADLKLLRSDMGRTAMCAAIVTDLCTWVLLVFGFASFSKSGTWNKMMPFVIITT 251 Query: 200 ILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLP 259 + IR K + G + L + + +I G+F+ GL + Sbjct: 252 AIFVLLCIFVIRPGIAWIFAKTV---KAGGVVLCGLITDACGVHSITGAFLFGLSIPHDH 308 Query: 260 EGKRIMEE-VRSIGYGLLIPIFFIHTGAMLNL-TVFRNADAIKLALVLSTIAVIGKVAGR 317 + ++EE + G+L+P+F+I G ++ + + D + +V+ + ++ V Sbjct: 309 IIRNMIEEKLHDFLSGILMPLFYIICGLRADIGFMLQFTDKFMMVVVICSSFLVKIVT-- 366 Query: 318 GFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALVDLMVAIHGGAISPDDVPKF 377 IT+ LF + M IG++ T+ L L+V G D P + Sbjct: 367 ---TVITS-------LFM--HIPMRDAFAIGALMNTKGTL-SLVVLNAGRDTKALDSPMY 413 Query: 378 IAATLIFITVSVLITPPLLKWAFREEVEAQRKARIESRKERIEKKKK 424 T+ + +S L+ PLL +A++ K ++ K R +K K Sbjct: 414 THMTIALLVMS-LVVEPLLAFAYKP------KKKLAHYKHRTVQKIK 453 >pir||T36239 probable integral membrane efflux protein - Streptomyces coelicolor >gi|4582390|emb|CAB40337.1| (AL049573) putative integral membrane efflux protein [Streptomyces coelicolor A3(2)] Length = 404 Score = 71.4 bits (172), Expect = 2e-11 Identities = 77/302 (25%), Positives = 135/302 (44%), Gaps = 29/302 (9%) Query: 3 PATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMG 62 P T +L + A++ + A R +P V+ E+ +G+++G V G D Sbjct: 4 PGTLVLI-LAAAVLAPLLVHATGRRVRVPLVIFEISLGIVMGPDV-LGWARPD------- 54 Query: 63 SSEVIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGY-FALRYMG 121 +V+D LA LG+ L+FL + D ++ L ++ + V L+ G AL G Sbjct: 55 --DVVDTLADLGLSMLIFLAGYEIDFAAVRGDTLRRSLWSWP---VALVAGIALALLVSG 109 Query: 122 YSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGS 181 EAF G LT+T++G + ++ D G LR G + + +F G + + + S Sbjct: 110 GDVFEAFVIGTALTSTTLGTVLPMLRDSGELRGRFGTVISAFGAVGEF-GPVIAVALLLS 168 Query: 182 GSLLGLSMKIIAFF--IITGILGWYSIDK---YIRFAERLHVEKGILGMAVGMMFL--FA 234 G S ++A F I T + W + + R ER G + M+ L Sbjct: 169 GRRPAESAALLAAFGAITTAAVFWALRPRPPWFARLTERTLHTSGQFAVRFVMLLLACML 228 Query: 235 ALAEGWFAAAIEGSFMMG-----LILSKLPEGK-RIMEEVRSIGYGLLIPIFFIHTGAML 288 LAE + + G+F G ++L P ++ +V ++G+G L+P+F++ TG Sbjct: 229 GLAEVFGLDVLLGAFAAGVLTRLVLLRAAPASSGEVLGKVEAMGFGFLVPLFYVVTGIEF 288 Query: 289 NL 290 +L Sbjct: 289 DL 290 >pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum pernix (strain K1) >gi|5106130|dbj|BAA81441.1| (AP000064) 412aa long hypothetical Na+/H+ antiporter [Aeropyrum pernix] Length = 412 Score = 71.0 bits (171), Expect = 2e-11 Identities = 68/278 (24%), Positives = 127/278 (45%), Gaps = 33/278 (11%) Query: 31 PGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVIDFLAKLGIIFLLFLGALDTDVEQ 90 PGV+ E+IMG +L ++G+ S +EV+ LA +G LLF+ + D+ Sbjct: 82 PGVV-EIIMGAMLA---FWGVKS----------TEVLTLLAAIGANLLLFMAGSEIDLAL 127 Query: 91 LKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREAFAGGVLLTATSIGLTVRVMMDLG 150 L+ A I L+ PL L Y+G S + L+ATS+ LT ++ Sbjct: 128 LRSILPQAVIVALVSALAPLALTALLHVYLGLSLTSSLVILASLSATSVALTYLLLSSYR 187 Query: 151 VLRSEVGAASLSASVMDDFLGIALIIFAVGSGS-----LLGLSMKIIAFFIITGILGWYS 205 ++RS +G +L+++++ D G+ ++ A S S + + + + + + LG Sbjct: 188 LVRSRLGQLALASAMLLDLSGMIMLNIATASISPSLAFYIVILLAALLLYPLLPRLGGAP 247 Query: 206 IDKYIRFAERLHVEKGILGMAVGMMFLFAALAEGWFAAAIEGSFMMGLILSKLPEGK-RI 264 + IR + G L VG+ ++ SF++G+I S+ + ++ Sbjct: 248 FEAEIRLITMTVIILGFLSDFVGV-------------HSVLTSFILGVIASETVRTRVQL 294 Query: 265 MEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADAIKLA 302 E++ S+ G P FFI +G ++ + + A+ LA Sbjct: 295 REKLESLATGFFTPFFFIASGMSIDPGIPLHYVALALA 332 >gb|AAD32281.1|AC006533_5 (AC006533) putative Na+/H+ antiporter [Arabidopsis thaliana] Length = 735 Score = 70.2 bits (169), Expect = 4e-11 Identities = 79/376 (21%), Positives = 163/376 (43%), Gaps = 41/376 (10%) Query: 66 VIDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHR 125 +++ A L +++ +FL L D+ +K + I ++G+ L+ G Sbjct: 2 LLETFANLALVYNVFLLGLGLDLRMIKIKDIKPVIIAIVGLLAALLAGAGLYYLPSNGEA 61 Query: 126 EAFAGGVLLTATSIGLT-----VRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVG 180 + G + + + G T R++ DL +LR+++G ++ A+V+ D L IF + Sbjct: 62 DKILAGCMYWSIAFGCTNFPDLARILADLKLLRTDMGHTAMCAAVVTDLCTWILFIFGMA 121 Query: 181 SGSLLGLSMKIIAFFIITGI----LGWYSIDKYIRFAERLHVEKGILG-----MAVGMMF 231 S G+ +++ + + + I L ++ I + + VE G +G + + Sbjct: 122 IFSKSGVRNEMLPYSLASTIAFVLLCYFVIQPGVAWIFNNTVEGGQVGDTHVWYTLAGVI 181 Query: 232 LFAALAEGWFAAAIEGSFMMGLILSKLPEG----KRIMEEVRSIGYGLLIPIFFIHTGAM 287 + + + E +I G+F+ GL +P K I E++ G+L+P+F+I G Sbjct: 182 ICSLITEVCGVHSITGAFLFGL---SIPHDHIIRKMIEEKLHDFLSGMLMPLFYIICGLR 238 Query: 288 LNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGI 347 ++ ++ + V+++ +V+ K+ F + +F R + L +G Sbjct: 239 ADIGYMNRTVSVGMMAVVTSASVMVKILSTMFCS-----------IFLRIPLRDGLAIGA 287 Query: 348 GSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAFREEVEAQ 407 + +ALV L A+ DV + TL F+ +S ++ PLL A++ Sbjct: 288 LMNTKGTMALVILNAGRDTKAL---DVIMYTHLTLAFLVMS-MVVQPLLAIAYK-----P 338 Query: 408 RKARIESRKERIEKKK 423 +K I + I+K K Sbjct: 339 KKKLIFYKNRTIQKHK 354 >pir||F70591 probable kefB protein - Mycobacterium tuberculosis (strain H37RV) >gi|2072703|emb|CAB08337.1| (Z95121) kefB [Mycobacterium tuberculosis] Length = 385 Score = 69.9 bits (168), Expect = 5e-11 Identities = 96/407 (23%), Positives = 172/407 (41%), Gaps = 44/407 (10%) Query: 1 MEPATWILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPIT 60 ME + +LF +GV L + + A+ RF L + L+ G+ LGN G+ + T Sbjct: 1 MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 Query: 61 MGSSEVIDFLAKLGIIFLL--FLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALR 118 V+ L LG+ F F +L L G+ ++ G +LG + Sbjct: 61 GAPIGVVLLLLALGLEFSATEFASSLR---HHLPSAGVDIVLNATPGAVAGWLLGLDGVA 117 Query: 119 YMGYSHREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDF-LGIALIIF 177 +G + GV ++S G+ R++ DL L + A LS V++DF + L +F Sbjct: 118 ILGLA-------GVTYISSS-GVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLF 169 Query: 178 AVGSGSLLGLSMKIIAFFIITGILGWYSID-KYIRFAERLHV---EKGILGMAVGMMFLF 233 AV + L + I +LG ++ ++ RL + +L +G+ + Sbjct: 170 AVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIV 229 Query: 234 AALAEGWFAAAIEGSFMMGLILS--KLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLT 291 AA+AE A+A G+F++GL L+ + ++ +R L IFF+ G L++ Sbjct: 230 AAVAESLHASAAVGAFLVGLTLTGETADRARMVLTPLRD----LFATIFFLGIG--LSVD 283 Query: 292 VFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIP 351 + + +AL L+ + KVA F A R + L+ G + Sbjct: 284 PGKLVSMLPVALALAAVTAATKVATGMFAARREGVAR-----------RGQLRAGTALVA 332 Query: 352 RTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKW 398 R E +L+ ++ + G +I P A ++ V ++ P L ++ Sbjct: 333 RGEFSLI--IIGLAGASI-----PGVAALATAYVFVMAIVGPILARY 372 >pir||A81330 probable glutathione-regulated potassium-efflux system protein Cj1231 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968664|emb|CAB73485.1| (AL139077) putative glutathione-regulated potassium-efflux system protein [Campylobacter jejuni] Length = 541 Score = 69.9 bits (168), Expect = 5e-11 Identities = 86/395 (21%), Positives = 173/395 (43%), Gaps = 44/395 (11%) Query: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67 L T+ +A++L + I ++FE+P ++G + G ++ + + G E I Sbjct: 9 LITVAIAIVL----NVIFKKFEIPTIIGYIAAGEIISEIYHLS-----------GKGE-I 52 Query: 68 DFLAKLGIIFLLFLGALDTDVEQL----KKTGLTATISTLMGVFVPLILGYFALRYMGYS 123 +A+ GI+FL+F L+ + L ++ L ++ L FV ++L A+ +G Sbjct: 53 THIAEFGIVFLMFTIGLEFSFKHLMAMKQEVFLNGSLQMLTCGFVFMLL---AIGILGLG 109 Query: 124 HREAFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI----IFAV 179 + A G L +S + ++++ D G + + G +L + D I L+ IF+ Sbjct: 110 DKSATIVGFALALSSTAVVLKILNDNGDINEQYGRKALGILLFQDIAVIPLLLLVDIFSS 169 Query: 180 GSGSL--LGLSMKIIAFFIITGI--LGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAA 235 + ++ L + I A +IT + +G Y +D+ R ++ + + M+ + Sbjct: 170 NNQNIEKLLFTSLISALILITLLFFIGKYLVDRIFRLIIHTSSQEIFISTVLFMVIGASF 229 Query: 236 LAEGWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRN 295 LA + + G+F+ G ++++ +I ++ LL+ +FFI G + L V Sbjct: 230 LANYFGFSYSLGAFIAGALIAETKYKHKIEADLIPF-RDLLLGLFFITVGMQIQLDVV-- 286 Query: 296 ADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEV 355 A L +VL T+ V+ G FG FL+T++ + I I + Sbjct: 287 AQNWFLIIVL-TLLVMALKFGIVFGFL---------FLYTKKRVALKTAFAIAQIGEFAL 336 Query: 356 ALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVL 390 A+ L+ A + I + ++ + IT +L Sbjct: 337 AIFSLLQAKNMLDIKTSQILIVVSILTMIITPFIL 371 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.328 0.145 0.418 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 141537896 Number of Sequences: 2977 Number of extensions: 5738030 Number of successful extensions: 22318 Number of sequences better than 1.0e-10: 42 Number of HSP's better than 0.0 without gapping: 8 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 22193 Number of HSP's gapped (non-prelim): 48 length of query: 426 length of database: 189,106,746 effective HSP length: 54 effective length of query: 372 effective length of database: 156,788,448 effective search space: 58325302656 effective search space used: 58325302656 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 40 (21.7 bits) S2: 166 (69.1 bits)