BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0396 (PAB0396) DE:peptide chain release factor aRF, subunit
1
(417 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75177 translation releasing factor aRF-1 PAB0396 - Pyrococ... 838 0.0
pir||H71036 translation releasing factor aRF-1 PH1584 - Pyrococc... 819 0.0
sp|Q58239|ERF1_METJA EUKARYOTIC-TYPE PEPTIDE CHAIN RELEASE FACTO... 416 e-115
pir||C69217 translation releasing factor aRF-1 MTH878 [similarit... 404 e-112
gi|11498819 peptide chain release factor eRF, subunit 1 [Archaeo... 390 e-107
emb|CAC11674.1| (AL445064) peptide chain release factor subunit ... 363 3e-99
gb|AAG20270.1| (AE005101) peptide chain release factor eRF-1; Er... 294 9e-79
pir||F72501 translation releasing factor aRF-1 APE1988 [similari... 274 1e-72
gb|AAK42492.1| Eukaryotic-type peptide chain release factor (sub... 264 1e-69
sp|P35615|ERF1_XENLA EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUB... 259 5e-68
pir||A71612 translation releasing factor eRF-1 PFB0550w - malari... 255 6e-67
sp|P35614|ERF1_ARATH EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUB... 254 1e-66
dbj|BAB11335.1| (AB016886) eukaryotic release factor 1 homolog [... 254 1e-66
gi|4759034 eukaryotic translation termination factor 1; polypept... 253 2e-66
gi|11416363 eukaryotic translation termination factor 1 [Homo sa... 253 2e-66
gb|AAA91169.1| (U40217) eukaryotic release factor 1 homolog [Ara... 253 3e-66
gb|AAF51574.1| (AE003591) CG5605 gene product [alt 1] [Drosophil... 252 7e-66
gb|AAC08410.1| (AF053983) translation release factor subunit 1 [... 251 1e-65
gb|AAF78496.1|AC012187_16 (AC012187) Identical to an omnipotent ... 249 3e-65
emb|CAA51935.1| (X73531) recessive omnipotent supressor [Sacchar... 245 7e-64
gi|6319619 Homolog of eRF1 (eukaryotic Release Factor 1) in othe... 245 7e-64
sp|P12385|ERF1_YEAST EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUB... 243 2e-63
pir||T31907 hypothetical protein T05H4.6 - Caenorhabditis elegan... 242 4e-63
pir||T43243 probable translation releasing factor eRF-1 [similar... 240 2e-62
gb|AAG25924.1|AF245454_1 (AF245454) peptide chain release factor... 238 1e-61
gb|AAF86346.1|AF278718_1 (AF278718) polypeptide chain release fa... 229 4e-59
emb|CAC14170.1| (AJ272501) polypeptide release factor eRF1a [Eup... 226 4e-58
gb|AAF74402.1|AF198107_2 (AF198107) eukaryotic release factor 1 ... 226 5e-58
emb|CAB77686.1| (AL161416) translation release factor 1 homolog ... 211 1e-53
gb|AAA36665.1| (M75715) TB3-1 [Homo sapiens] 207 2e-52
dbj|BAA85336.1| (AB026195) eRF1 [Tetrahymena thermophila] 205 1e-51
dbj|BAA13439.1| (D87691) eRF1 [Mus musculus] 176 3e-43
pir||S31445 omnipotent suppressor protein SUP1 homolog (clone A1... 154 2e-36
pir||E69086 cell division protein - Methanobacterium thermoautot... 84 3e-15
pir||G75110 cell division protein pelota (pela) PAB0468 - Pyroco... 81 2e-14
>pir||E75177 translation releasing factor aRF-1 PAB0396 - Pyrococcus abyssi
(strain Orsay) >gi|5458010|emb|CAB49500.1| (AJ248284)
peptide chain release factor aRF, subunit 1 [Pyrococcus
abyssi]
Length = 417
Score = 838 bits (2141), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 1 MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK 60
MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK
Sbjct: 1 MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK 60
Query: 61 SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVR 120
SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVR
Sbjct: 61 SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVR 120
Query: 121 LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAG 180
LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAG
Sbjct: 121 LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAG 180
Query: 181 GQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYL 240
GQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYL
Sbjct: 181 GQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYL 240
Query: 241 HHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLAT 300
HHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLAT
Sbjct: 241 HHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLAT 300
Query: 301 YGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCP 360
YGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCP
Sbjct: 301 YGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCP 360
Query: 361 KCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
KCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI
Sbjct: 361 KCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
>pir||H71036 translation releasing factor aRF-1 PH1584 - Pyrococcus horikoshii
>gi|3258013|dbj|BAA30696.1| (AP000006) 417aa long
hypothetical eukaryotic peptide chain release factor
subunit 1 [Pyrococcus horikoshii]
Length = 417
Score = 819 bits (2093), Expect = 0.0
Identities = 402/417 (96%), Positives = 414/417 (98%)
Query: 1 MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK 60
MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK
Sbjct: 1 MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK 60
Query: 61 SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVR 120
SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSE+EGNTDIRLWAI+PPEPLNVR
Sbjct: 61 SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEIEGNTDIRLWAIIPPEPLNVR 120
Query: 121 LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAG 180
LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIE+LDELTSNVPGKTRAG
Sbjct: 121 LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIELLDELTSNVPGKTRAG 180
Query: 181 GQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYL 240
GQSARRYERIREQETHEFMKRIGEHANR FLPLLEKGELKGII+GGPGPTKE+FVEG+YL
Sbjct: 181 GQSARRYERIREQETHEFMKRIGEHANRAFLPLLEKGELKGIIIGGPGPTKEEFVEGEYL 240
Query: 241 HHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLAT 300
HHELKKKI+GVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLAT
Sbjct: 241 HHELKKKILGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLAT 300
Query: 301 YGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCP 360
YGEREVRRALEIGAVD LLISEGY+KVRVR KCNHCGWEELKTMSEEE+EVY+KK+T+CP
Sbjct: 301 YGEREVRRALEIGAVDVLLISEGYNKVRVRVKCNHCGWEELKTMSEEEYEVYRKKITKCP 360
Query: 361 KCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
KCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI
Sbjct: 361 KCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
>sp|Q58239|ERF1_METJA EUKARYOTIC-TYPE PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 (ERF1)
>gi|2129177|pir||E64403 translation releasing factor
aRF-1 MJ0829 - Methanococcus jannaschii
>gi|1591516|gb|AAB98828.1| (U67526) peptide chain
release factor aRF, subunit 1 [Methanococcus jannaschii]
Length = 425
Score = 416 bits (1058), Expect = e-115
Identities = 210/412 (50%), Positives = 291/412 (69%), Gaps = 4/412 (0%)
Query: 10 QLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVL 69
QLY KK ++ELK +G+GTELISLYIPAG +S V Q LREE S A NIKSK+TRKNV
Sbjct: 12 QLYLFKKMLKELKSKKGKGTELISLYIPAGRRISDVAQHLREEMSQASNIKSKSTRKNVQ 71
Query: 70 GALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTD-IRLWAIVPPEPLNVRLYRCDQTF 128
A+E +Q LKL K+ E G+ +F G V T+ + + I PPEP+ +YRCD F
Sbjct: 72 SAIEAILQRLKLLKEPLEKGVVIFAGMVPRSGPGTEKMETYVIEPPEPIKTYIYRCDSEF 131
Query: 129 VTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYE 188
EPLEE L KDAYG+I V++NEATI L++G+ I +L +LTS VPGK +AGGQSARR E
Sbjct: 132 YLEPLEEFLEDKDAYGVILVDRNEATIALVKGRNINILKKLTSGVPGKFKAGGQSARRLE 191
Query: 189 RIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKI 248
R+ + HEF++R+G+ AN FLPLL++ +L+GI+VGGPG TK +FVEGDYLHHELKK +
Sbjct: 192 RLIDLAAHEFLQRVGQKANEQFLPLLQEKKLRGILVGGPGHTKNEFVEGDYLHHELKKIV 251
Query: 249 IGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVK-DTGLATYGEREVR 307
+ D+ Y E+G+REL+EKA+ +L+D E+++E++ V FLK ++K D GLA YGE+EV
Sbjct: 252 LDTFDLCYTEEFGIRELLEKAAPLLKDVELMKEREAVQRFLKELIKEDGGLACYGEKEVL 311
Query: 308 RALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKL--TRCPKCGSQ 365
AL +GAVDTL++SE +K +V+ CN+C + E KT+++ E +++L +CPKCG
Sbjct: 312 EALMMGAVDTLIVSEELEKYKVKIACNNCDYLEEKTVNKLELIKLEEELKNAQCPKCGGA 371
Query: 366 NLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
+E+ D E L ++ E++G+ + +S +TEEG AF G+ AILR+KI
Sbjct: 372 LSIVEEKDYIEYLSELCEQSGAKLVTVSSETEEGAMILNAFKGIAAILRYKI 423
>pir||C69217 translation releasing factor aRF-1 MTH878 [similarity] -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621972|gb|AAB85376.1| (AE000864) peptide chain
release factor eRF, subunit 1 [Methanobacterium
thermoautotrophicum]
Length = 407
Score = 404 bits (1028), Expect = e-112
Identities = 202/408 (49%), Positives = 278/408 (67%), Gaps = 10/408 (2%)
Query: 10 QLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVL 69
+L+E K+ ++EL RGRGTEL+S+YIP +S V + +REE S + NIKSK T+KNV
Sbjct: 8 ELFEFKRTLQELSDKRGRGTELVSVYIPPDRQISDVAKHMREELSQSANIKSKQTKKNVQ 67
Query: 70 GALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTD-IRLWAIVPPEPLNVRLYRCDQTF 128
A+E MQ LKL+ + PE GL +FVG V T+ + + PPEP+ +Y C+ F
Sbjct: 68 SAIEVIMQRLKLFPKPPEKGLVMFVGMVPRGGPGTEKMETYVFEPPEPIKTYIYHCNSEF 127
Query: 129 VTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYE 188
EPL EML K+ YGL +++ EATI L+GKRI++L LTS VPGK +AGGQS RR++
Sbjct: 128 YLEPLREMLEEKETYGLAVLDRKEATIATLKGKRIDILKTLTSGVPGKHKAGGQSQRRFD 187
Query: 189 RIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKI 248
R+ + HEF+KRIGEH N FL + +LKGII+GGPG TKE+F+ GDYLHHELKKK+
Sbjct: 188 RLIDLAAHEFLKRIGEHMNEAFLQI---DDLKGIILGGPGHTKEEFLNGDYLHHELKKKV 244
Query: 249 IGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRR 308
I VD SY GE+G+RE+++K+ D+L + +V+REKKLV FL+ ++ + GLA+YGEREVR+
Sbjct: 245 ITTVDTSYTGEFGIREVIDKSMDVLSEIDVMREKKLVQRFLRELINEDGLASYGEREVRQ 304
Query: 309 ALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLT 368
L++GAV+ LL+SE R +C CG KT + CP C Q
Sbjct: 305 HLQMGAVEVLLLSEDLKYQRGTYECASCGHRMEKTGRD------LPDTETCPSCNDQMRL 358
Query: 369 IEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFK 416
++ D+ ++L++MAEE G++VEIIS +TEEG Q RAFGG+GAILR++
Sbjct: 359 SDRRDMIDDLVEMAEEVGTEVEIISTETEEGMQLLRAFGGIGAILRYR 406
>gi|11498819 peptide chain release factor eRF, subunit 1 [Archaeoglobus
fulgidus] >gi|7443566|pir||C69402 translation releasing
factor aRF-1 AF1220 - Archaeoglobus fulgidus
>gi|2649371|gb|AAB90026.1| (AE001020) peptide chain
release factor eRF, subunit 1 [Archaeoglobus fulgidus]
Length = 407
Score = 390 bits (991), Expect = e-107
Identities = 205/409 (50%), Positives = 276/409 (67%), Gaps = 15/409 (3%)
Query: 11 LYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLG 70
+YE K+K+EEL+K +GRGTELI+LYIP +++ V QLR E S A NIKSK TR NVL
Sbjct: 6 MYEFKRKLEELEKYKGRGTELITLYIPPDKNIADVSNQLRSELSQASNIKSKQTRTNVLA 65
Query: 71 ALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFVT 130
+E + LK +++ PENG+ + G V+ + G I PPEP+ + Y CD F
Sbjct: 66 GIEAILNRLKHFRKPPENGMVIISGVVN-INGKEKHITEIIEPPEPVPLYKYHCDSKFYL 124
Query: 131 EPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERI 190
+PL+EML K YGLI +++ EAT+GLL+GKRIEVLD TS VPGK R GGQS+ R+ER+
Sbjct: 125 DPLKEMLTEKKLYGLIVLDRREATVGLLKGKRIEVLDWDTSMVPGKHRQGGQSSVRFERL 184
Query: 191 REQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKIIG 250
RE HEF K++GE A+ LP K +L GI++GGP PTKE+F EG+YLHHEL+KK++G
Sbjct: 185 REIAIHEFYKKVGEMASEALLPY--KDKLIGILIGGPSPTKEEFYEGEYLHHELQKKVLG 242
Query: 251 VVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRAL 310
+ D+ Y E GL ELVEKA D+L++ ++IREK L+ FLK V +D GLA YGE EVRR +
Sbjct: 243 LFDVGYTDESGLYELVEKAKDVLQEVDIIREKNLMQRFLKEVARD-GLAAYGEEEVRRYI 301
Query: 311 EIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNL--- 367
E+GAVDTLL+SE RV+ +C CG E T+ E + + P C N+
Sbjct: 302 ELGAVDTLLLSEDLRYERVKYRCPKCGKEVEVTVRE--------GIEKPPFCEEDNVEME 353
Query: 368 TIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFK 416
+E+ D+ EL ++AE G+ VE +S ++EEG+ Y+AFGG+ AILRFK
Sbjct: 354 EVERRDIVLELSELAESTGAKVEFLSTESEEGEMLYKAFGGIAAILRFK 402
>emb|CAC11674.1| (AL445064) peptide chain release factor subunit 1 related protein
[Thermoplasma acidophilum]
Length = 417
Score = 363 bits (921), Expect = 3e-99
Identities = 193/405 (47%), Positives = 262/405 (64%), Gaps = 10/405 (2%)
Query: 12 YELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLGA 71
YE K+ +EEL K+ GRGTELISLYIP +S V+ LR+EYST+ NIKSK+TRKNVL A
Sbjct: 13 YEFKRALEELSKLHGRGTELISLYIPPDKQISDVVAYLRDEYSTSSNIKSKSTRKNVLAA 72
Query: 72 LERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFVTE 131
+E M LK YK P NG F G+++ T++ I PPEP+ +Y+CD F E
Sbjct: 73 IESIMARLKYYKTPPPNGFVFFEGHIATRGDQTEMYTKIIEPPEPITTFMYKCDSEFHLE 132
Query: 132 PLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERIR 191
L+ ML K+ YGLI +++ EAT+G L G RIEV+D + S VP K GGQS+RR+ER+
Sbjct: 133 MLKTMLEEKEIYGLIVIDRKEATVGFLNGTRIEVVDNVQSQVPSKHHQGGQSSRRFERLI 192
Query: 192 EQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKIIGV 251
E +EF K++GE AN F+P ++ +++ I +GGPG TKE F E DYL +E+K+KI +
Sbjct: 193 EIAANEFFKKVGEIANNAFMPKIK--DIRAIFLGGPGATKEYFFEKDYLRNEVKEKIKDL 250
Query: 252 VDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVK-DTGLATYGEREVRRAL 310
D+ Y E GLRELVEKAS+ ++D ++ +EK L+N FL+ V K D GLA YGE+ +R AL
Sbjct: 251 FDVGYTDESGLRELVEKASESIKDMKISKEKDLMNRFLREVRKPDGGLAIYGEQAIRDAL 310
Query: 311 EIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLTIE 370
E VD LLISEG KVR +C C E E+ V C K G+ +
Sbjct: 311 EQKMVDLLLISEGLRKVRYTYRCPTCQAELTLNQEPNEWPV-------CEKDGTPMELVA 363
Query: 371 KWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRF 415
+ D E+L ++A+E+G+ VEIIS +EEG+ +AFGG+ A+LRF
Sbjct: 364 EDDFIEDLYRLAKESGAQVEIISDQSEEGKLLKQAFGGMAAVLRF 408
>gb|AAG20270.1| (AE005101) peptide chain release factor eRF-1; Erf1 [Halobacterium
sp. NRC-1]
Length = 438
Score = 294 bits (746), Expect = 9e-79
Identities = 160/414 (38%), Positives = 244/414 (58%), Gaps = 18/414 (4%)
Query: 8 DAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKN 67
D + YE +K IEELK G GT+L+++YIP +S V+ + +E+S A NIKSK TR N
Sbjct: 33 DRRKYEFRKVIEELKDYEGSGTQLVTIYIPPDKQISDVVAHVTQEHSEASNIKSKQTRTN 92
Query: 68 VLGALERAMQHLKLYKQ-TPENGLALFVGNVSEMEGNTDIRLWAIV-PPEPLNVRLYRCD 125
V AL L+ Y P+NG+ +F G V G TD+ + PP+P+ Y CD
Sbjct: 93 VQDALTSIKDRLRYYDTFPPDNGMVVFSGAVDSGGGRTDMVTEVLESPPQPIESFRYHCD 152
Query: 126 QTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSAR 185
F+TEPL EML K YGLI +++ E+ +G L+GKR++ + S VPGK R GGQSA+
Sbjct: 153 SAFLTEPLAEMLGDKGLYGLIVLDRRESNVGWLKGKRVQPVKSAESLVPGKQRKGGQSAQ 212
Query: 186 RYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELK 245
R+ R+R + F + + A+ +F+P ++ E+ GI+VGGP PTK++F++GDYLHHEL+
Sbjct: 213 RFARLRLEAIDNFYQEVAGMADDLFVP--KRHEIDGILVGGPSPTKDEFLDGDYLHHELQ 270
Query: 246 KKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGERE 305
K++G D+SY E GL +LV+ L + +++ +K + EF + + LATYG +
Sbjct: 271 DKVLGKFDVSYTDESGLSDLVDAGQAALAEADLMDDKSDMEEFFEE-LNGGKLATYGFEQ 329
Query: 306 VRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLT----RCPK 361
RR L +G+VD LL+SE + V +C + EE+E ++ T C
Sbjct: 330 TRRNLIMGSVDRLLVSEDLREDVVIYECPN---------DHEEYETIDRRNTSPEHTCSD 380
Query: 362 CGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRF 415
CG + +++ D + L+ +A++ G++ IS D E+G+Q AFGG ILR+
Sbjct: 381 CGEEATEVDREDAIDHLMSIADQRGTETHFISTDFEKGEQLLTAFGGYAGILRY 434
>pir||F72501 translation releasing factor aRF-1 APE1988 [similarity] - Aeropyrum
pernix (strain K1) >gi|5105686|dbj|BAA80998.1|
(AP000063) 341aa long hypothetical eukaryotic peptide
chain release factor subunit 1 [Aeropyrum pernix]
Length = 341
Score = 274 bits (693), Expect = 1e-72
Identities = 160/388 (41%), Positives = 215/388 (55%), Gaps = 52/388 (13%)
Query: 31 LISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLGALERAMQHLKLYKQTPENGL 90
L+SLYIP G LS VM LR+EYS NIK K TR+ V AL AM L++ TP NGL
Sbjct: 2 LLSLYIPPGRPLSDVMTLLRQEYSITDNIKLKRTRQAVKRALSAAMDRLQMLTSTPPNGL 61
Query: 91 ALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFVTEPLEEMLRVKDAYGLITVEK 150
LF G E + PPEP+ V YR D+ F+T+ LE+M+ +A G+I VE+
Sbjct: 62 VLFCG---EDMSTGKFECFMFSPPEPIRVFYYRTDKRFITDFLEDMVEDNNAIGIIIVER 118
Query: 151 NEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERIREQETHEFMKRIGEHANRVF 210
++ATIGLL+G R+EVL EL VPGK + GGQS RRYERI EQ EF K++GE A+ +
Sbjct: 119 DQATIGLLKGARLEVLKELEGFVPGKHKMGGQSQRRYERIIEQMVDEFFKKVGEEASNLL 178
Query: 211 LPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKII-GVVDISYHGEYGLRELVEKA 269
+PL EKG LKG+IV GPG K++FVEG+YL + LKK + +VD++Y G GL+E V KA
Sbjct: 179 VPLAEKGVLKGVIVAGPGLAKQEFVEGNYLDYRLKKILAPELVDVAYQGLQGLKEAVMKA 238
Query: 270 SDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRALEIGAVDTLLISEGYDKVRV 329
++ + EF H+ K TG+ YGE++V ALE+GAV TLLI E + +
Sbjct: 239 EKVVEAQMYRDAVNAMEEFKLHLAKGTGMIVYGEKDVEAALEMGAVKTLLIHESREDL-- 296
Query: 330 RAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLTIEKWDVAEELIKMAEEAGSDV 389
EE ++ A+ +G+ V
Sbjct: 297 ----------------------------------------------EEWVEKAKSSGAQV 310
Query: 390 EIISLDTEEGQQFYRAFGGLGAILRFKI 417
++ E + F + FGGL ILRF+I
Sbjct: 311 IVVPESLAEAEWFLKTFGGLAGILRFRI 338
>gb|AAK42492.1| Eukaryotic-type peptide chain release factor (subunit 1)
[Sulfolobus solfataricus]
Length = 357
Score = 264 bits (668), Expect = 1e-69
Identities = 135/310 (43%), Positives = 200/310 (63%), Gaps = 4/310 (1%)
Query: 14 LKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLGALE 73
+K I+ELKK + T L+SLYIP G + V+ LR+EYS AQNIK K TR VL A+
Sbjct: 1 MKALIKELKKWKAPATVLLSLYIPPGRPIPDVVNLLRQEYSIAQNIKLKRTRDAVLSAIG 60
Query: 74 RAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFVTEPL 133
A+ L + NGL LF G + E D + + PP+ + + YR D+ F E L
Sbjct: 61 AAIDRLNKIPKIDGNGLVLFCGENFDTE---DFKCFMFSPPDKVPLFFYRTDKEFHLEFL 117
Query: 134 EEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERIREQ 193
E+M+ YGLI VE++EATIGLL+G RIE+L+E+ VPGK GGQS RR +RI ++
Sbjct: 118 EDMVEDTAVYGLIIVERDEATIGLLKGARIEILEEIEGFVPGKHMMGGQSQRRIDRIIDE 177
Query: 194 ETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKII-GVV 252
H F+K +GE N F+P ++ G++KG+++GGPG KEDF + DY+ + +K I+ ++
Sbjct: 178 MYHNFLKEVGEKVNAYFMPFVQNGKMKGVLLGGPGYAKEDFYKEDYVDYRIKNLILQPLI 237
Query: 253 DISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRALEI 312
D+S GE GLRE++ KA D+L++ + I +KL+ E H+ KD GL YG+ ++++A+EI
Sbjct: 238 DVSDQGEVGLREMIMKAEDLLKNQQYIEVEKLLEELKYHLAKDDGLIIYGKEQIKKAMEI 297
Query: 313 GAVDTLLISE 322
GA++ ++I E
Sbjct: 298 GAIEAIVIHE 307
>sp|P35615|ERF1_XENLA EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 (ERF1)
(OMNIPOTENT SUPPRESSOR PROTEIN 1 HOMOLOG) (SUP1 HOMOLOG)
>gi|477078|pir||A48061 translation releasing factor
eRF-1 - African clawed frog >gi|64632|emb|CAA78620.1|
(Z14253) XLCL1 [Xenopus laevis]
Length = 437
Score = 259 bits (654), Expect = 5e-68
Identities = 138/410 (33%), Positives = 234/410 (56%), Gaps = 3/410 (0%)
Query: 8 DAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKN 67
+ +++++KK I+ L+ RG GT +ISL IP +S+V + L +E+ TA NIKS+ R +
Sbjct: 11 NVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLS 70
Query: 68 VLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQT 127
VLGA+ Q LKLY + P NGL ++ G + EG P +P+N LY CD
Sbjct: 71 VLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNK 130
Query: 128 FVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRY 187
F TE L +L +G I ++ + A G L+G EVL + T ++P K GGQSA R+
Sbjct: 131 FHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRF 190
Query: 188 ERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKK 247
R+R ++ H +++++ E A ++F+ +K + G+++ G K + + D L+ K
Sbjct: 191 ARLRMEKRHNYVRKVAETAVQLFISG-DKVNVAGLVLAGSADFKTELSQSDMFDQRLQSK 249
Query: 248 IIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVR 307
++ +VDISY GE G + +E ++++L + + I+EKKL+ + + +DTG +G +
Sbjct: 250 VLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTL 309
Query: 308 RALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNL 367
+ALE+GAV+ L++ E D +R +CN G EE KT+ + K + G ++
Sbjct: 310 KALEMGAVEILIVYENLDTMRYVLRCN--GSEEEKTLYLTPEQEKDKSHFIDKETGQEHE 367
Query: 368 TIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
IE + E ++ G+ +EI++ ++EG QF + FGG+G ILR+++
Sbjct: 368 LIESMPLLEWFANSYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRV 417
>pir||A71612 translation releasing factor eRF-1 PFB0550w - malaria parasite
(Plasmodium falciparum) >gi|3845214|gb|AAC71899.1|
(AE001402) eukaryotic peptide chain release factor
[Plasmodium falciparum]
Length = 427
Score = 255 bits (645), Expect = 6e-67
Identities = 141/419 (33%), Positives = 233/419 (54%), Gaps = 13/419 (3%)
Query: 4 MTRHDAQL--YELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKS 61
M HDA + +++K+ I++L+ +G GT +ISL I ++S++ + L +E TA NIKS
Sbjct: 1 MEDHDANVEQWKIKRLIKKLENAKGNGTSMISLIIKNKDEVSRINKMLADELGTASNIKS 60
Query: 62 KTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRL 121
+ R +VL A+ Q LKLY +TP GL ++ G V +G P P+N L
Sbjct: 61 RVNRLSVLSAITSTQQKLKLYNKTPPKGLVVYCGTVITEDGKEKKMSIDFEPFRPINTSL 120
Query: 122 YRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGG 181
Y CD F E L+E+L D +G I V+ N A G ++G EV+ T ++P K GG
Sbjct: 121 YLCDNKFHVEALKELLESDDKFGFIIVDGNGALFGTIQGNTREVIRRFTVDLPKKHGRGG 180
Query: 182 QSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLH 241
QSA R+ R+R ++ H +++++ E A VF+ +K + GI++ G K D + D
Sbjct: 181 QSALRFARLRLEKRHNYVRKVAEVATSVFI-TNDKVNVTGIVLAGSADFKNDLLNSDMFD 239
Query: 242 HELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATY 301
L K+I +VDISY G+ G + +E +S+ L++ + I+EKKL+ +F + + +DTG Y
Sbjct: 240 QRLFAKVIKIVDISYGGDNGFNQAIELSSEALQNVKFIQEKKLIGKFFEEIAQDTGKVVY 299
Query: 302 GEREVRRALEIGAVDTLLISEGYDKVRVRAK---CNHCGWEELKTMSEEEFEVYKKKLTR 358
G + +ALEIGAV+ L++ EG D +R+ K N + E++ +YK+
Sbjct: 300 GIDDTLKALEIGAVELLILYEGLDIIRLTTKNPVTNQTKTMHISPCDEKQESLYKENNVE 359
Query: 359 CPKCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
+EK + + +I ++ G+ ++ ++ ++EG QF + FGG G +LR+KI
Sbjct: 360 LE-------VVEKISLTDWVIGNYKKYGASLDFVTNKSQEGAQFQKGFGGFGGMLRYKI 411
>sp|P35614|ERF1_ARATH EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 (ERF1)
(OMNIPOTENT SUPPRESSOR PROTEIN 1 HOMOLOG) (SUP1 HOMOLOG)
>gi|322554|pir||S31328 omnipotent suppressor protein
SUP1 homolog (clone G18) - Arabidopsis thaliana
>gi|16514|emb|CAA49172.1| (X69375) similar to yeast
omnipotent suppressor protein SUP1 (SUP45) [Arabidopsis
thaliana] >gi|1402882|emb|CAA66813.1| (X98130)
eukaryotic early release factor subunit 1-like protein
[Arabidopsis thaliana] >gi|1495249|emb|CAA66118.1|
(X97486) eRF1-3 [Arabidopsis thaliana]
Length = 435
Score = 254 bits (642), Expect = 1e-66
Identities = 136/409 (33%), Positives = 230/409 (55%), Gaps = 3/409 (0%)
Query: 10 QLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVL 69
+++++KK I+ L+ RG GT +ISL +P +++V + L +EY TA NIKS+ R++VL
Sbjct: 11 EIWKIKKLIKGLETARGNGTSMISLIMPPRDQVARVTKMLADEYGTASNIKSRVNRQSVL 70
Query: 70 GALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFV 129
A+ A Q LKLY + P NGL L+ G + +G P +P+N LY CD F
Sbjct: 71 SAITSAQQRLKLYNKVPPNGLVLYTGTIVTDDGKEKKVTIDFEPFKPINASLYLCDNKFH 130
Query: 130 TEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYER 189
TEPL E+L D +G I ++ N G L G EVL + T ++P K GGQSA R+ R
Sbjct: 131 TEPLNELLESDDKFGFIVMDGNGTLFGTLSGNTREVLHKFTVDLPKKHGRGGQSALRFAR 190
Query: 190 IREQETHEFMKRIGEHANRVFL-PLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKI 248
+R ++ H ++++ E A + ++ P + + G+I+ G K + + + L+ KI
Sbjct: 191 LRMEKRHNYVRKTAELATQFYINPATSQPNVSGLILAGSADFKTELSQSELFDPRLQAKI 250
Query: 249 IGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRR 308
+ VVD+SY GE G + +E +++IL + + I+EKKL+ ++ + + +DTG +G + +
Sbjct: 251 LNVVDVSYGGENGFNQAIELSAEILSNVKFIQEKKLIGKYFEEISQDTGKYVFGVEDTLK 310
Query: 309 ALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLT 368
ALE+GAV+TL++ E D R K N G +K + +++ + + ++
Sbjct: 311 ALEMGAVETLIVWENLDINRYELKNNTTGEIVIKHLGKDQEN--NQSNFHDAETNAELEV 368
Query: 369 IEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
EK + E + G +E ++ ++EG QF R FGG+G +LR+++
Sbjct: 369 QEKMPLLEWFANEYKRFGCTLEFVTNKSQEGSQFCRGFGGIGGLLRYQL 417
>dbj|BAB11335.1| (AB016886) eukaryotic release factor 1 homolog [Arabidopsis
thaliana]
Length = 436
Score = 254 bits (642), Expect = 1e-66
Identities = 140/412 (33%), Positives = 229/412 (54%), Gaps = 9/412 (2%)
Query: 10 QLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVL 69
+++++KK I+ L+ RG GT +ISL +P +S+V + L +EY TA NIKS+ R++VL
Sbjct: 12 EIWKIKKLIKSLEAARGNGTSMISLIMPPRDQVSRVTKMLGDEYGTASNIKSRVNRQSVL 71
Query: 70 GALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFV 129
GA+ A Q LKLY + P NGL L+ G + +G P P+N LY CD F
Sbjct: 72 GAITSAQQRLKLYNRVPPNGLVLYTGTIVNEDGKEKKVTIDFEPFRPINASLYLCDNKFH 131
Query: 130 TEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYER 189
TE L E+L D +G I ++ N G L G EVL + + ++P K GGQSA R+ R
Sbjct: 132 TEALNELLESDDKFGFIVMDGNGTLFGTLSGNTREVLHKFSVDLPKKHGRGGQSALRFAR 191
Query: 190 IREQETHEFMKRIGEHANRVFL-PLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKI 248
+R ++ H ++++ E A + ++ P + + G+I+ G K + + D L KI
Sbjct: 192 LRMEKRHNYVRKTAELATQYYINPATSQPNVSGLILAGSADFKTELSQSDMFDPRLAAKI 251
Query: 249 IGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRR 308
+ VVD+SY GE G + +E +++IL + + I+EK+L+ ++ + + +DTG +G +
Sbjct: 252 LNVVDVSYGGENGFNQAIELSAEILANVKFIQEKRLIGKYFEEISQDTGKYVFGVEDTLN 311
Query: 309 ALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLT 368
ALE GA++TL++ E D R K + G +K +++E+ + T K +L
Sbjct: 312 ALESGAIETLIVWENLDINRYVMKNSATGETVIKHLNKEQ-----EANTENFKVADSDLA 366
Query: 369 I---EKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
+ EK + E L G +E ++ ++EG QF R FGG+G ILR+++
Sbjct: 367 LDVEEKLSLLEWLANEYRRFGCALEFVTNKSQEGSQFCRGFGGIGGILRYQL 418
>gi|4759034 eukaryotic translation termination factor 1; polypeptide chain
release factor 1; sup45 (yeast omnipotent suppressor 45)
homolog-like 1 [Homo sapiens]
>gi|1169547|sp|P46055|ERF1_HUMAN EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR SUBUNIT 1 (ERF1) (TB3-1) (C11
PROTEIN) >gi|1082824|pir||S50853 translation releasing
factor eRF-1 [validated] - human >gi|6980844|pdb|1DT9|A
Chain A, The Crystal Structure Of Human Eukaryotic
Release Factor Erf1-Mechanism Of Stop Codon Recognition
And Peptidyl-Trna Hydrolysis >gi|1491704|emb|CAA57281.1|
(X81625) C11 protein [Homo sapiens]
>gi|1890300|gb|AAB49726.1| (U90176) eukaryotic release
factor 1 [Homo sapiens] >gi|2275012|emb|CAA57282.1|
(X81626) C11 protein [Mesocricetus auratus]
>gi|5499721|gb|AAD43966.1|AF095901_1 (AF095901) eRF1
[Homo sapiens] >gi|6070211|dbj|BAA85489.1| (AB029089)
eukaryotic polypeptide chain release factor 1
[Oryctolagus cuniculus]
Length = 437
Score = 253 bits (640), Expect = 2e-66
Identities = 136/410 (33%), Positives = 234/410 (56%), Gaps = 3/410 (0%)
Query: 8 DAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKN 67
+ +++++KK I+ L+ RG GT +ISL IP +S+V + L +E+ TA NIKS+ R +
Sbjct: 11 NVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLS 70
Query: 68 VLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQT 127
VLGA+ Q LKLY + P NGL ++ G + EG P +P+N LY CD
Sbjct: 71 VLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNK 130
Query: 128 FVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRY 187
F TE L +L +G I ++ + A G L+G EVL + T ++P K GGQSA R+
Sbjct: 131 FHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRF 190
Query: 188 ERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKK 247
R+R ++ H +++++ E A ++F+ +K + G+++ G K + + D L+ K
Sbjct: 191 ARLRMEKRHNYVRKVAETAVQLFIS-GDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSK 249
Query: 248 IIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVR 307
++ +VDISY GE G + +E ++++L + + I+EKKL+ + + +DTG +G +
Sbjct: 250 VLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTL 309
Query: 308 RALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNL 367
+ALE+GAV+ L++ E D +R C E++ ++ E+ E K T + G ++
Sbjct: 310 KALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQ-EKDKSHFTD-KETGQEHE 367
Query: 368 TIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
IE + E ++ G+ +EI++ ++EG QF + FGG+G ILR+++
Sbjct: 368 LIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRV 417
>gi|11416363 eukaryotic translation termination factor 1 [Homo sapiens]
Length = 479
Score = 253 bits (640), Expect = 2e-66
Identities = 136/410 (33%), Positives = 234/410 (56%), Gaps = 3/410 (0%)
Query: 8 DAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKN 67
+ +++++KK I+ L+ RG GT +ISL IP +S+V + L +E+ TA NIKS+ R +
Sbjct: 53 NVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLS 112
Query: 68 VLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQT 127
VLGA+ Q LKLY + P NGL ++ G + EG P +P+N LY CD
Sbjct: 113 VLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNK 172
Query: 128 FVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRY 187
F TE L +L +G I ++ + A G L+G EVL + T ++P K GGQSA R+
Sbjct: 173 FHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRF 232
Query: 188 ERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKK 247
R+R ++ H +++++ E A ++F+ +K + G+++ G K + + D L+ K
Sbjct: 233 ARLRMEKRHNYVRKVAETAVQLFIS-GDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSK 291
Query: 248 IIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVR 307
++ +VDISY GE G + +E ++++L + + I+EKKL+ + + +DTG +G +
Sbjct: 292 VLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTL 351
Query: 308 RALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNL 367
+ALE+GAV+ L++ E D +R C E++ ++ E+ E K T + G ++
Sbjct: 352 KALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQ-EKDKSHFTD-KETGQEHE 409
Query: 368 TIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
IE + E ++ G+ +EI++ ++EG QF + FGG+G ILR+++
Sbjct: 410 LIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRV 459
>gb|AAA91169.1| (U40217) eukaryotic release factor 1 homolog [Arabidopsis thaliana]
Length = 436
Score = 253 bits (639), Expect = 3e-66
Identities = 140/412 (33%), Positives = 229/412 (54%), Gaps = 9/412 (2%)
Query: 10 QLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVL 69
+++++KK I+ L+ RG GT +ISL +P +S+V + L +EY TA NIKS+ R++VL
Sbjct: 12 EIWKIKKLIKSLEAARGNGTSMISLIMPPRDQVSRVTKMLGDEYGTASNIKSRVNRQSVL 71
Query: 70 GALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFV 129
GA+ A Q LKLY + P NGL L+ G + +G P P+N LY CD F
Sbjct: 72 GAITSAQQRLKLYNRVPPNGLVLYTGTIVNEDGKEKKVTIDFEPFRPINGSLYLCDNKFH 131
Query: 130 TEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYER 189
TE L E+L D +G I ++ N G L G EVL + + ++P K GGQSA R+ R
Sbjct: 132 TEALNELLESDDKFGFIVMDGNGTLFGTLSGNTREVLHKFSVDLPKKHGRGGQSALRFAR 191
Query: 190 IREQETHEFMKRIGEHANRVFL-PLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKI 248
+R ++ H ++++ E A + ++ P + + G+I+ G K + + D L KI
Sbjct: 192 LRMEKRHNYVRKTAELATQYYINPATSQPNVSGLILAGSADFKTELSQSDMFDPRLAAKI 251
Query: 249 IGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRR 308
+ VVD+SY GE G + +E +++IL + + I+EK+L+ ++ + + +DTG +G +
Sbjct: 252 LNVVDVSYGGENGFNQAIELSAEILANVKFIQEKRLIGKYFEEISQDTGKYVFGVEDTLN 311
Query: 309 ALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLT 368
ALE GA++TL++ E D R K + G +K +++E+ + T K +L
Sbjct: 312 ALESGAIETLIVWENLDINRYVMKNSATGETVIKHLNKEQ-----EANTENFKVADSDLA 366
Query: 369 I---EKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
+ EK + E L G +E ++ ++EG QF R FGG+G ILR+++
Sbjct: 367 LDVEEKLSLLEWLANEYRRFGCALEFVTNKSQEGSQFCRGFGGIGGILRYQL 418
>gb|AAF51574.1| (AE003591) CG5605 gene product [alt 1] [Drosophila melanogaster]
>gi|7296285|gb|AAF51575.1| (AE003591) CG5605 gene
product [alt 2] [Drosophila melanogaster]
Length = 464
Score = 252 bits (636), Expect = 7e-66
Identities = 141/410 (34%), Positives = 227/410 (54%), Gaps = 2/410 (0%)
Query: 8 DAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKN 67
+ +++++KK I+ L+ RG GT +ISL IP +S+V + L +E+ TA NIKS+ R +
Sbjct: 11 NVEIWKIKKLIKSLEMARGNGTSMISLIIPPKDQISRVSKMLADEFGTASNIKSRVNRLS 70
Query: 68 VLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQT 127
VLGA+ LKLY + P NGL ++ G + EG P +P+N LY CD
Sbjct: 71 VLGAITSVQHRLKLYTKVPPNGLVIYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNK 130
Query: 128 FVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRY 187
F TE L +L + +G I ++ N A G L+G EVL + T ++P K GGQSA R+
Sbjct: 131 FHTEALTALLADDNKFGFIVMDGNGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRF 190
Query: 188 ERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKK 247
R+R ++ H +++++ E A ++F+ +K + G+I+ G K + + D L+ K
Sbjct: 191 ARLRMEKRHNYVRKVAEVATQLFI-TNDKPNIAGLILAGSADFKTELSQSDMFDPRLQSK 249
Query: 248 IIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVR 307
+I +VD+SY GE G + +E A++ L++ + I+EKKL+ + + +DTG +G +
Sbjct: 250 VIKLVDVSYGGENGFNQAIELAAESLQNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTL 309
Query: 308 RALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNL 367
RALE+G+V+TL+ E D R K NH + + K + G +
Sbjct: 310 RALELGSVETLICWENLDIQRYVLK-NHANSTSTTVLHLTPEQEKDKSHFTDKESGVEME 368
Query: 368 TIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
IE + E L + G+ +EII+ ++EG QF R FGG+G ILR+K+
Sbjct: 369 LIESQPLLEWLANNYKMFGATLEIITDKSQEGSQFVRGFGGIGGILRYKV 418
>gb|AAC08410.1| (AF053983) translation release factor subunit 1 [Podospora
anserina]
Length = 435
Score = 251 bits (634), Expect = 1e-65
Identities = 137/408 (33%), Positives = 228/408 (55%), Gaps = 3/408 (0%)
Query: 10 QLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVL 69
+++++KK I+ L+ RG GT +ISL IP +S+ + L EEY TA NIKS+ R++VL
Sbjct: 14 EIWKVKKLIKRLEAARGNGTSMISLIIPPKDQISRAAKMLAEEYGTASNIKSRVNRQSVL 73
Query: 70 GALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFV 129
A+ Q LKLY + P NGL ++ G + EG P +P+N LY CD F
Sbjct: 74 SAITSTQQRLKLYNKVPPNGLVVYCGEILTSEGKERKVNIDFEPFKPINTSLYLCDNKFH 133
Query: 130 TEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYER 189
TE L E+L +G I ++ N A G L G +++ + + ++P K GGQSA R+ R
Sbjct: 134 TEALAELLESDQKFGFIVMDGNGALFGTLSGNTRDIVHKFSVDLPKKHGRGGQSALRFAR 193
Query: 190 IREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKII 249
+RE++ H +++++ E A + F+ +K + GI++ G K D D L K+I
Sbjct: 194 LREEKRHNYVRKVAELAVQNFITN-DKVNVMGIVLAGSADFKNDLNASDMFDQRLATKVI 252
Query: 250 GVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRA 309
VVD+SY GE G + +E AS+ L + + I+EKKL+ ++ + + +DTG YG + +A
Sbjct: 253 KVVDVSYGGENGFNQAIELASETLGNVKFIQEKKLIGKYFEEISQDTGRICYGVEDTLKA 312
Query: 310 LEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLTI 369
LE+GAV+TL++ E + R K ++ E+ S ++ + + + G + +
Sbjct: 313 LELGAVETLIVFENLEVTRWVLKDSN--GAEIIIHSTKQQDAANRDRFMDKETGQEMEVV 370
Query: 370 EKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
+ E + + ++ G+ +E +S + EG QF + FGG+G ILR+K+
Sbjct: 371 SQESFLEWIAEHYKDFGTTLEFVSDRSTEGNQFVKGFGGIGGILRYKV 418
>gb|AAF78496.1|AC012187_16 (AC012187) Identical to an omnipotent supressor protein SUP1
homolog (fragment) from Arabidopsis thaliana gi|322525
and is a member of the eRF1 PF|01605 family. ESTs
gb|Z18188, gb|H36000, gb|AA651147, gb|W43754 come from
this gene
Length = 434
Score = 249 bits (630), Expect = 3e-65
Identities = 135/418 (32%), Positives = 231/418 (54%), Gaps = 3/418 (0%)
Query: 1 MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK 60
M++ + +++++KK I+ L+ RG GT +ISL +P +S+V + L +EY TA NIK
Sbjct: 1 MAEEADTNIEIWKIKKLIKGLESARGNGTSMISLIMPPRDQVSRVTKMLGDEYGTASNIK 60
Query: 61 SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVR 120
S+ R++VL A+ A Q LKLY + P NGL L+ G + +G + P P+N
Sbjct: 61 SRVNRQSVLSAITSAQQRLKLYNKVPTNGLVLYTGTIVNDDGKEKKVTFDFEPFRPINAS 120
Query: 121 LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAG 180
LY CD F TE L E+L D +G I ++ N G L G EVL + T ++P K G
Sbjct: 121 LYLCDNKFHTEALNELLESDDKFGFIVMDGNGTLFGTLSGNTREVLHKFTVDLPKKHGRG 180
Query: 181 GQSARRYERIREQETHEFMKRIGEHANRVFL-PLLEKGELKGIIVGGPGPTKEDFVEGDY 239
GQSA R+ R+R ++ H ++++ E A + ++ P + + G+I+ G K + + +
Sbjct: 181 GQSALRFARLRMEKRHNYVRKTAELATQFYINPATSQPNVSGLILAGSADFKTELSQSEL 240
Query: 240 LHHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLA 299
L+ KI+ VVD+SY GE G + +E +++IL + + I+EKKL+ ++ + + +DTG
Sbjct: 241 FDPRLQAKILNVVDVSYGGENGFNQAIELSAEILSNVKFIQEKKLIGKYFEEISQDTGKY 300
Query: 300 TYGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRC 359
+G + +ALE+GA++TL++ E D R K + G +K +++
Sbjct: 301 VFGVEDTLKALEMGAIETLIVWENLDINRYELKNSTTGEMVVKHFGKDQES--DTSNFHD 358
Query: 360 PKCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
+ ++ EK + E + G +E ++ ++EG QF R FGG+G +LR+++
Sbjct: 359 SETNAELEVQEKMPLLEWFANEYKRFGCTLEFVTNKSQEGSQFCRGFGGIGGMLRYQL 416
>emb|CAA51935.1| (X73531) recessive omnipotent supressor [Saccharomyces cerevisiae]
Length = 432
Score = 245 bits (619), Expect = 7e-64
Identities = 135/417 (32%), Positives = 226/417 (53%), Gaps = 5/417 (1%)
Query: 1 MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK 60
M + +++++KK ++ L+K RG GT +ISL IP + + L +EY TA NIK
Sbjct: 1 MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIK 60
Query: 61 SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVR 120
S+ R +VL A+ Q LKLY P+NGL L+ G++ +G + I P +P+N
Sbjct: 61 SRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTS 120
Query: 121 LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAG 180
LY CD F TE L E+L+ D +G I ++ G + G VL + T ++P K G
Sbjct: 121 LYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRG 180
Query: 181 GQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYL 240
GQSA R+ R+RE++ H +++++ E A + F+ +K +KG+I+ G K D + +
Sbjct: 181 GQSALRFARLREEKRHNYVRKVAEVAVQNFI-TNDKVNVKGLILAGSADFKTDLAKSELF 239
Query: 241 HHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLAT 300
L K+I +VD+SY GE G + +E +++ L + + ++EKKL+ + + +DTG
Sbjct: 240 DPRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFC 299
Query: 301 YGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCP 360
YG + +AL++GAV+ L++ E + +R K E+ + + E E K
Sbjct: 300 YGIDDTLKALDLGAVEKLIVFENLETIRYTFK----DAEDNEVIKFAEPEAKDKSFAIDK 355
Query: 361 KCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
G + + + + E L + G+ +E I+ + EG QF FGG+GA+LR+K+
Sbjct: 356 ATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKV 412
>gi|6319619 Homolog of eRF1 (eukaryotic Release Factor 1) in other metazoans.;
Sup45p [Saccharomyces cerevisiae] >gi|626763|pir||S46014
omnipotent suppressor protein SUP45 - yeast
(Saccharomyces cerevisiae) >gi|536444|emb|CAA85101.1|
(Z36012) ORF YBR143c [Saccharomyces cerevisiae]
Length = 437
Score = 245 bits (619), Expect = 7e-64
Identities = 135/417 (32%), Positives = 226/417 (53%), Gaps = 5/417 (1%)
Query: 1 MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK 60
M + +++++KK ++ L+K RG GT +ISL IP + + L +EY TA NIK
Sbjct: 1 MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIK 60
Query: 61 SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVR 120
S+ R +VL A+ Q LKLY P+NGL L+ G++ +G + I P +P+N
Sbjct: 61 SRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTS 120
Query: 121 LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAG 180
LY CD F TE L E+L+ D +G I ++ G + G VL + T ++P K G
Sbjct: 121 LYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRG 180
Query: 181 GQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYL 240
GQSA R+ R+RE++ H +++++ E A + F+ +K +KG+I+ G K D + +
Sbjct: 181 GQSALRFARLREEKRHNYVRKVAEVAVQNFI-TNDKVNVKGLILAGSADFKTDLAKSELF 239
Query: 241 HHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLAT 300
L K+I +VD+SY GE G + +E +++ L + + ++EKKL+ + + +DTG
Sbjct: 240 DPRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFC 299
Query: 301 YGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCP 360
YG + +AL++GAV+ L++ E + +R K E+ + + E E K
Sbjct: 300 YGIDDTLKALDLGAVEKLIVFENLETIRYTFK----DAEDNEVIKFAEPEAKDKSFAIDK 355
Query: 361 KCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
G + + + + E L + G+ +E I+ + EG QF FGG+GA+LR+K+
Sbjct: 356 ATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKV 412
>sp|P12385|ERF1_YEAST EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 (ERF1)
(OMNIPOTENT SUPPRESSOR PROTEIN 1)
>gi|4593|emb|CAA27719.1| (X04082) SUP1 gene product (aa
1-437) [Saccharomyces cerevisiae]
Length = 437
Score = 243 bits (615), Expect = 2e-63
Identities = 135/417 (32%), Positives = 226/417 (53%), Gaps = 5/417 (1%)
Query: 1 MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK 60
M + +++++KK ++ L+K RG GT +ISL IP + + L +EY TA NIK
Sbjct: 1 MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGLIPLYQKMLTDEYGTASNIK 60
Query: 61 SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVR 120
S+ R +VL A+ Q LKLY P+NGL L+ G++ +G + I P +P+N
Sbjct: 61 SRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTS 120
Query: 121 LYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAG 180
LY CD F TE L E+L+ D +G I ++ G + G VL + T ++P K G
Sbjct: 121 LYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRG 180
Query: 181 GQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYL 240
GQSA R+ R+RE++ H +++++ E A + F+ +K +KG+I+ G K D + +
Sbjct: 181 GQSALRFARLREEKRHNYVRKVAEVAVQNFI-TNDKVNVKGLILAGSADFKTDLAKSELF 239
Query: 241 HHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLAT 300
L K+I +VD+SY GE G + +E +++ L + + ++EKKL+ + + +DTG
Sbjct: 240 DPRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFC 299
Query: 301 YGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCP 360
YG + +AL++GAV+ L++ E + +R K E+ + + E E K
Sbjct: 300 YGIDDTLKALDLGAVEKLIVFENLETIRYTFK----DAEDNEVIKFAEPEAKDKSFAIDK 355
Query: 361 KCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
G + + + + E L + G+ +E I+ + EG QF FGG+GA+LR+K+
Sbjct: 356 ATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKV 412
>pir||T31907 hypothetical protein T05H4.6 - Caenorhabditis elegans
>gi|2315514|gb|AAB66012.1| (AF016452) Similar to
eukaryotic peptide chain release factor subunit 1; coded
for by C. elegans cDNA yk6h9.5; coded for by C. elegans
cDNA yk6h9.3 [Caenorhabditis elegans]
Length = 443
Score = 242 bits (612), Expect = 4e-63
Identities = 138/410 (33%), Positives = 227/410 (54%), Gaps = 4/410 (0%)
Query: 8 DAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKN 67
+ +++++K+ I+ L+ RG GT +ISL IP ++++ + L EEY TA NIKS+ R +
Sbjct: 19 NVEMWKIKRLIKSLELARGNGTSMISLIIPPKDQVARIQRMLAEEYGTASNIKSRVNRLS 78
Query: 68 VLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQT 127
VLGA+ LKLY + P NGL ++ G + EG P + +N LY CD
Sbjct: 79 VLGAITSVQGRLKLYNKVPPNGLVVYCGTIMTDEGKEKKVNIDFEPFKAINTSLYLCDNK 138
Query: 128 FVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRY 187
F TE L+ +L + +G I ++ N G L+G EVL + T ++P K GGQSA R+
Sbjct: 139 FHTEALQGLLADDNKFGFIIMDGNGCLFGTLQGNTREVLHKFTVDLPKKHGRGGQSAVRF 198
Query: 188 ERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKK 247
R+R ++ H +++++ E++ F+ +K + G+I+ G K + + D L+ K
Sbjct: 199 ARLRNEKRHNYVRKVAENSVEQFIK-NDKVTVAGLILAGSADFKTELGQSDMFDQRLQAK 257
Query: 248 IIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVR 307
+I VDI+Y GE G + +E A+D L + I+EKKL+ + + +DTG +G ++
Sbjct: 258 MIKTVDIAYGGENGFNQAIELAADTLASVKFIQEKKLIGGYFDEISQDTGKYVFGVKDTL 317
Query: 308 RALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNL 367
ALE+GA++TL+ E D VR + K N G + L + +E E K T + G
Sbjct: 318 AALEMGAIETLICWENLDIVRYKMK-NSLGEDILLNLRPDE-EKDKSHFTD-SETGQDME 374
Query: 368 TIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
IE + E + G+ +EI++ ++EG QF R FGG+G +LR+++
Sbjct: 375 IIETMPLLEWFANNYKNFGAALEIVTDKSQEGAQFVRGFGGIGGLLRYRV 424
>pir||T43243 probable translation releasing factor eRF-1 [similarity] - fission
yeast (Schizosaccharomyces pombe)
>gi|1881399|dbj|BAA09933.1| (D63883) sup45
[Schizosaccharomyces pombe] >gi|7019761|emb|CAB75769.1|
(AL157734) translation release factor subunit 1.
[Schizosaccharomyces pombe]
Length = 433
Score = 240 bits (606), Expect = 2e-62
Identities = 135/419 (32%), Positives = 233/419 (55%), Gaps = 5/419 (1%)
Query: 1 MSKMTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIK 60
MS+ +++++++ +++L G GT +I+L IP G +S+ L EEY TA NIK
Sbjct: 1 MSETAEKAIEIWKIRRLVKQLINCHGNGTSMITLIIPPGEQISRYSNMLAEEYGTASNIK 60
Query: 61 SKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPP-EPLNV 119
S+ R +VL A+ + LKLY + P+NGL ++ G V MEGN +L P +P+N
Sbjct: 61 SRVNRLSVLSAITSTRERLKLYNKVPDNGLVIYCGEVI-MEGNKTRKLNIDFEPFKPINT 119
Query: 120 RLYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRA 179
Y CD F TE L E+L +G I ++ ++ G++ G EVL T ++P K
Sbjct: 120 SQYLCDNKFHTEALAELLESDQRFGFIVMDGHQTLYGVVSGSAREVLQRFTVDLPKKHGR 179
Query: 180 GGQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDY 239
GGQSA R+ R+R+++ H +++++ E A + F+ +K + GI++ G K + + D
Sbjct: 180 GGQSALRFARLRDEKRHNYVRKVAEGAVQHFI-TDDKPNVAGIVLAGSADFKTELGQSDL 238
Query: 240 LHHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLA 299
L+ +II VD+SY G+ G + +E A+D L + + ++EKKL+ F + D+G
Sbjct: 239 FDQRLQSRIIKTVDVSYGGDAGFNQAIELAADTLSNVKYVQEKKLIQRFFDEISLDSGKY 298
Query: 300 TYGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRC 359
+G + AL+ GAV+TLL D +R K N G + M++E+ E
Sbjct: 299 CFGVVDTMNALQEGAVETLLCFADLDMIRYEFK-NSEGNPVITYMTKEQEEKDSTNSFLL 357
Query: 360 PK-CGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
K G++ + ++E L + ++ G+++E +S ++EG QF + FGG+GA++R+++
Sbjct: 358 DKDTGAEMELVSSMLLSEWLAEHYKDYGANLEFVSDRSQEGMQFVKGFGGIGAVMRYQL 416
>gb|AAG25924.1|AF245454_1 (AF245454) peptide chain release factor 1b [Euplotes octocarinatus]
Length = 437
Score = 238 bits (600), Expect = 1e-61
Identities = 132/412 (32%), Positives = 225/412 (54%), Gaps = 7/412 (1%)
Query: 8 DAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKN 67
+ + + +K+ I+ L+K+RG GT +ISL + +SKV L E TA NIKS+ R+
Sbjct: 7 NVETWRIKRLIKNLEKLRGDGTSMISLLLSPRDQISKVQAMLAGEAGTAVNIKSRVNRQA 66
Query: 68 VLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQT 127
VL A+ A + LKLY +TP NGL ++ G V + + P PLN Y CD
Sbjct: 67 VLSAITSAKERLKLYSKTPTNGLVVYCGTVIGEDDSEKKYTIDFEPFRPLNTFKYICDNK 126
Query: 128 FVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRY 187
F TEPL E+L D +G + V+ N G L+G ++L ++T ++P K GGQSA R+
Sbjct: 127 FCTEPLFELLENDDVFGFVIVDGNGCLFGTLQGNTKKILQQITVSLPKKHGRGGQSAPRF 186
Query: 188 ERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKK 247
RIRE++ H +++++ E A + F+ ++ +KG+++ G K D E D L +
Sbjct: 187 GRIREEKRHNYVRKVAELATQHFI-TDDRPNVKGLVLAGSANFKNDLSESDLFDKRLSEV 245
Query: 248 IIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVR 307
+I +VD+SY GE G + + A D L + + + EK L++++ + + D+G+ +G +
Sbjct: 246 VIKIVDVSYGGENGFSQAISLAEDALSNVKFVEEKNLISKYFEEIALDSGMIVFGVEDTL 305
Query: 308 RALEIGAVDTLLISEGYD--KVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQ 365
+LE+GA+D L+ E + + +R N +E+K + + + K + K G+
Sbjct: 306 HSLEVGALDLLMCFENLEINRYEIRDPAN----DEIKIYNLNKEQEKDSKYFKNEKTGTD 361
Query: 366 NLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
++ ++E L + + G +E I+ ++EG QF FGG+G LR+K+
Sbjct: 362 LEIVKCVALSEWLCENYSKYGVKLEFITDKSQEGFQFVNGFGGIGGFLRYKL 413
>gb|AAF86346.1|AF278718_1 (AF278718) polypeptide chain release factor 1 [Trypanosoma brucei]
Length = 452
Score = 229 bits (578), Expect = 4e-59
Identities = 134/409 (32%), Positives = 217/409 (52%), Gaps = 7/409 (1%)
Query: 12 YELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLGA 71
Y++KK I+ L+ RG GT +IS+Y+ +S ++ +L EY TA NIKS T + +V A
Sbjct: 16 YKVKKLIQMLESARGMGTSVISIYMTPKEQISGMVTKLNNEYGTASNIKSHTNKLSVQSA 75
Query: 72 LERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFVTE 131
+ ++ LK Y + P NGL L+ G V E I P +P++ LY CD F TE
Sbjct: 76 ITASLGRLKQYNRLPPNGLLLYCGTVLTAENKEKKLTLDIEPFKPVSRSLYLCDNKFHTE 135
Query: 132 PLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERIR 191
L ML + +G I V+ + T L G E L T +P K GGQS R+ RIR
Sbjct: 136 ELHRMLESDEKFGFIVVDGSGTTYATLCGSVKEKLSSFTVELPKKHGRGGQSKNRFARIR 195
Query: 192 EQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKIIGV 251
+ H +++++ E A ++F+ ++ + G+++ G KE + D LK ++ V
Sbjct: 196 MERRHNYLRKVAEGATQLFI-TNDRPNIVGLVLAGSAEFKEVLYQSDLFDPRLKAIVVKV 254
Query: 252 VDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRALE 311
VD+++ G+ GL + ++ A+D L ++++EKKL+ F + DT L +G ++ + LE
Sbjct: 255 VDVAHPGDVGLNQAIDLAADALSGVKLVQEKKLLQGFFDQIACDTQLYCFGVQDTLKCLE 314
Query: 312 IGAVDTLLISEGYDKVRVRAKCNHCGWEE---LKTMSEEEFEVYKKKLTRCPKCGSQNLT 368
GAV+TL++ E + R N +E + MSEEE K+ + G
Sbjct: 315 AGAVETLIVYEDLNIYRYTVVKNRGADDEETFVHVMSEEE---AKRSNIHMQESGKTRNE 371
Query: 369 IEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
IE+ D + L + G +E+I+ ++EG QF R FGG+G +LR+K+
Sbjct: 372 IEQEDFVDWLATNYRKFGCALELITNRSQEGTQFVRGFGGIGGVLRYKL 420
>emb|CAC14170.1| (AJ272501) polypeptide release factor eRF1a [Euplotes
octocarinatus]
Length = 446
Score = 226 bits (570), Expect = 4e-58
Identities = 133/419 (31%), Positives = 223/419 (52%), Gaps = 12/419 (2%)
Query: 8 DAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKN 67
+ + +++K+ I+ L+++RG GT +ISL + + KV L EY TA++IKSK R
Sbjct: 7 NVETWKIKRIIKNLERLRGNGTSMISLLLSPRDAIPKVQGMLAGEYGTAESIKSKINRLA 66
Query: 68 VLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQT 127
V GA+ A + LKLY +TP NGL ++ G V + + P PLN Y CD
Sbjct: 67 VQGAITSAKERLKLYNRTPPNGLVIYCGIVIGEDKSEKKYCIDFEPFRPLNTFKYICDNK 126
Query: 128 FVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRY 187
F T+PL E+L D +G + V+ + G L+G +++ +T ++P K GGQSA R+
Sbjct: 127 FYTKPLFELLENDDVFGFVIVDGSGCLFGTLQGNTKKIIQNITVSLPKKHGRGGQSAPRF 186
Query: 188 ERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKK 247
RIRE++ H +++++ E A + F+ +K +KGII+ G K D E D L +
Sbjct: 187 GRIREEKRHNYVRKVAEFATQHFI-TEDKPNVKGIILAGSANFKNDLSESDLFDKRLSEI 245
Query: 248 IIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVR 307
++ +VD+SY GE G + + A D L + + + EK L++++ + + +DTG+ +G +
Sbjct: 246 VLKIVDVSYGGENGFSQAITLAEDTLSNVKFVEEKNLISKYFEEIAQDTGMVVFGIEDTL 305
Query: 308 RALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTM----SEEEFEVYKKKLTRCPKCG 363
+LE+GAV T++ E + R + + EE+K + ++ YK
Sbjct: 306 NSLELGAVGTIICFENLEINRYEIR--NPSTEEIKVIHLCKDQQNDTRYKMIDNNYSYFI 363
Query: 364 SQNLTIEK-----WDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
QN ++ + E L + + G +E I+ ++EG QF FGG+G LRFK+
Sbjct: 364 DQNTGLDLEILSCVPLTEWLCENYSKYGVRLEFITDKSQEGFQFVNGFGGIGGFLRFKL 422
>gb|AAF74402.1|AF198107_2 (AF198107) eukaryotic release factor 1 [Giardia intestinalis]
Length = 457
Score = 226 bits (569), Expect = 5e-58
Identities = 141/421 (33%), Positives = 221/421 (52%), Gaps = 22/421 (5%)
Query: 11 LYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLG 70
+++LK+ IE+L+ G GT +ISL IP G LS V L EY TA NIKS+ + VL
Sbjct: 20 IWQLKRTIEKLESYTGSGTSVISLLIPPGEQLSSVTGMLTNEYGTASNIKSRVNKNAVLS 79
Query: 71 ALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFVT 130
A+ AM LKLY + P NGLA++ G + E NT + + P +P++ +Y CD F T
Sbjct: 80 AITSAMSRLKLYNRLPPNGLAVYCGEIEEDGKNTKVVI-DYTPYKPISNFIYLCDSKFHT 138
Query: 131 EPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERI 190
E L E+L D +G I ++ E + L G +LD T ++P K GGQS+ R+ R+
Sbjct: 139 EHLRELLTNDDTFGFIIMDGKETLMATLSGTVRTILDRSTVDLPKKHGRGGQSSVRFARL 198
Query: 191 REQETHEFMKRIGEHANRVFLPLLEKGELK----GIIVGGPGPTKEDFVEGDYLHHELKK 246
RE+ H +++++ E AN +F+ G K G+I+GG K L+
Sbjct: 199 REEARHNYVRKVAERANSLFISSGPTGTNKPIVSGLILGGSADFKNVLSTSAIFDQRLQS 258
Query: 247 KIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREV 306
++ +DI+Y GE G + +E A D L+D ++I+E KL+ EF +++ KDT +G +
Sbjct: 259 IVMKQIDINYGGEQGFNQAIEMAGDTLKDVKLIQEVKLLTEFTENIAKDTKRVCFGITDT 318
Query: 307 RRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEE-------LKT-MSEEEF--EVYKKKL 356
R LE+ AV+ L++ + RV +C G LK+ MS ++ EV +
Sbjct: 319 IRCLEMSAVEKLIVWDDLPYHRVTLQCVINGETSAPVIKYLLKSQMSNPKYLREVINGEE 378
Query: 357 TRCPKCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFK 416
+ G Q L E + + G+ +E I+ + EG QF FGG+G +LR++
Sbjct: 379 VQLDIMGDQLL-------LEWFVDNYKNYGASLEFITNRSAEGTQFCSGFGGIGGLLRWQ 431
Query: 417 I 417
+
Sbjct: 432 V 432
>emb|CAB77686.1| (AL161416) translation release factor 1 homolog [Leishmania major]
Length = 453
Score = 211 bits (531), Expect = 1e-53
Identities = 126/409 (30%), Positives = 212/409 (51%), Gaps = 7/409 (1%)
Query: 12 YELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLGA 71
Y++KK I+ L+ RG GT +IS+Y+ ++ ++ +L EY TA NIKS T + +V A
Sbjct: 17 YKVKKLIQMLESARGMGTSVISVYMTPKEQIAGMVAKLNNEYGTASNIKSHTNKLSVQSA 76
Query: 72 LERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFVTE 131
+ A+ LK + P NGL L+ G V + I P + ++ LY CD F TE
Sbjct: 77 ITAALGRLKQIPRVPANGLLLYSGTVMTADNKEKKLTLDIEPFKAVSRSLYLCDNKFHTE 136
Query: 132 PLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERIR 191
L ML D +G I ++ + +T + G E L T +P K GGQS R+ RIR
Sbjct: 137 ELRRMLESDDKFGFIIMDGSGSTFATVCGDVKEKLGSFTVELPKKHGRGGQSKNRFARIR 196
Query: 192 EQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKIIGV 251
+ H +++++ E A F+ ++ ++G+++ G KE + D LK+ ++ +
Sbjct: 197 MERRHNYVRKVAETAVSYFI-TNDRPNVRGLVLAGSADFKEVLFQSDLFDPRLKEVVVKI 255
Query: 252 VDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRALE 311
VD+++ G+ GL + ++ ++D L ++++EKKL+ F + DT +G + R LE
Sbjct: 256 VDVAHPGDVGLNQAIDLSADALSGVKLVQEKKLLQTFFDQIAMDTQQYCFGVNDTMRCLE 315
Query: 312 IGAVDTLLISEGYDKVR---VRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLT 368
GAV+TL+ E R ++ K E+ ++E E KK + G
Sbjct: 316 AGAVETLICFEDLQVNRYVIIKNKGAEDETTEIHLLTEAE---ASKKNIHAHEAGKTQNE 372
Query: 369 IEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
IE + + L + ++ G +E+IS ++EG Q R FGG+G ILR+K+
Sbjct: 373 IESENFVDWLAQNYQKFGCTLELISDRSQEGTQLVRGFGGIGGILRYKM 421
>gb|AAA36665.1| (M75715) TB3-1 [Homo sapiens]
Length = 428
Score = 207 bits (522), Expect = 2e-52
Identities = 119/409 (29%), Positives = 213/409 (51%), Gaps = 4/409 (0%)
Query: 8 DAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKN 67
+ +++++KK I+ L+ RG GT +ISL IP +S+V + L +E+ TA NIKS+ R +
Sbjct: 11 NVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLS 70
Query: 68 VLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQT 127
VLGA+ Q LKLY + P NGL ++ G + EG P +P+N LY CD
Sbjct: 71 VLGAITSVQQRLKLYNKVPPNGLEVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNK 130
Query: 128 FVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRY 187
F TE L +L +G I ++ + A G L+G EVL + T ++P K GGQSA R+
Sbjct: 131 FHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRF 190
Query: 188 ERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKK 247
R+R ++ H +++++ E A ++F+ +K + G+++ G K + + D L+ K
Sbjct: 191 ARLRMEKRHNYVRKVAETAVQLFIS-GDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSK 249
Query: 248 IIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVR 307
++ +VDISY GE G + +E ++++L + + I+EKKL+ + + +D+ +T ++
Sbjct: 250 VLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDSLASTVLALKIH 309
Query: 308 RALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNL 367
+GAV+ S + K C+ + + + K + G ++
Sbjct: 310 IGFGMGAVEN---SNSHMKSGYNEICSSLPRHRRRNLYLTPEQEKDKSHFTDKETGQEHE 366
Query: 368 TIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFK 416
IE + E + ++ ++ ++G + FGG+G ILR++
Sbjct: 367 LIESMPLLEWFANNYKNLELRWKLSQINHKKGLSLMKGFGGIGGILRYQ 415
>dbj|BAA85336.1| (AB026195) eRF1 [Tetrahymena thermophila]
Length = 435
Score = 205 bits (515), Expect = 1e-51
Identities = 124/407 (30%), Positives = 215/407 (52%), Gaps = 7/407 (1%)
Query: 12 YELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLGA 71
+++KK + L+ RG GT ++SL IP ++ + + +E+S A NIK + R++V A
Sbjct: 14 FKIKKLMTRLRNTRGSGTSMVSLIIPPKKQINDSTKLISDEFSKATNIKDRVNRQSVQDA 73
Query: 72 LERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFVTE 131
+ A+Q LKLY++TP NGL L+ G V EG L P +P+N LY CD F +
Sbjct: 74 MVSALQRLKLYQRTPNNGLILYCGKVLNEEGKEIKLLIDFEPYKPINTSLYFCDSKFHVD 133
Query: 132 PLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERIR 191
L +L +G I ++ A L+G VL++ + +P K GGQS+ R+ R+R
Sbjct: 134 ELGSLLETDPPFGFIVMDGQGALYANLQGNTKTVLNKFSVELPKKHGRGGQSSVRFARLR 193
Query: 192 EQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKIIGV 251
++ H +++++ E A + F+ +K ++G+++ G G K + L KII +
Sbjct: 194 VEKRHNYLRKVCEVATQTFIS-QDKINVQGLVLAGSGDFKNELSTTQMFDPRLACKIIKI 252
Query: 252 VDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRALE 311
VD+SY GE GL + +E A + L + + ++EK ++++F + D+G YG ++ + L
Sbjct: 253 VDVSYGGENGLNQAIELAQESLTNVKFVQEKNVISKFFDCIAIDSGTVVYGVQDTMQLLL 312
Query: 312 IGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNL-TIE 370
G ++ +L E +RV K + E++ + E+ K K G L IE
Sbjct: 313 DGVIENILCFEELTTLRVTRK--NKVTEQITHIFIPPNELNNPKHF---KDGEHELEKIE 367
Query: 371 KWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
++ E L + E G+++ I+ + EG QF + F G+G LR+K+
Sbjct: 368 VENLTEWLAEHYSEFGAELYFITDKSAEGCQFVKGFSGIGGFLRYKV 414
>dbj|BAA13439.1| (D87691) eRF1 [Mus musculus]
Length = 338
Score = 176 bits (443), Expect = 3e-43
Identities = 95/305 (31%), Positives = 172/305 (56%), Gaps = 3/305 (0%)
Query: 113 PPEPLNVRLYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSN 172
P +P+N LY CD F TE L +L +G I ++ + A G L+G EVL + T +
Sbjct: 17 PFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVD 76
Query: 173 VPGKTRAGGQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKE 232
+P K GGQSA R+ R+R ++ H +++++ E A ++F+ ++ + G+++ G K
Sbjct: 77 LPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISG-DQVNVAGLVLAGSADFKT 135
Query: 233 DFVEGDYLHHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHV 292
+ + D L+ K++ +VDISY GE G + +E ++++L + + I+EKKL+ + +
Sbjct: 136 ELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEI 195
Query: 293 VKDTGLATYGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVY 352
+DTG +G + +ALE+GAV L++ E D +R C E++ ++ E+ E
Sbjct: 196 SQDTGKYCFGVEDTLKALEMGAVQILIVYENLDIMRYVLHCQGTEEEKILYLTPEQ-EKD 254
Query: 353 KKKLTRCPKCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAI 412
K T + G ++ IE + E ++ G+ +EI++ ++EG QF + FGG+G I
Sbjct: 255 KSHFTD-KETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGI 313
Query: 413 LRFKI 417
LR+++
Sbjct: 314 LRYRV 318
>pir||S31445 omnipotent suppressor protein SUP1 homolog (clone A18) -
Arabidopsis thaliana (fragment)
>gi|16512|emb|CAA49171.1| (X69374) similar to yeast
omnipotent suppressor protein SUP1 (SUP45); ORF
[Arabidopsis thaliana]
Length = 304
Score = 154 bits (385), Expect = 2e-36
Identities = 85/288 (29%), Positives = 155/288 (53%), Gaps = 3/288 (1%)
Query: 131 EPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERI 190
E L E+L D +G I ++ N G L G EVL + T ++P K GGQSA R+ R+
Sbjct: 1 EALNELLESDDKFGFIVMDGNGTLFGTLSGNTREVLHKFTVDLPKKHGRGGQSALRFARL 60
Query: 191 REQETHEFMKRIGEHANRVFL-PLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKII 249
R ++ H ++++ E A + ++ P + + G+I+ G K + + + L+ KI+
Sbjct: 61 RMEKRHNYVRKTAELATQFYINPATSQPNVSGLILAGSADFKTELSQSELFDPRLQAKIL 120
Query: 250 GVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRA 309
VVD+SY GE G + +E +++IL + + I+EKKL+ ++ + + +DTG +G + +A
Sbjct: 121 NVVDVSYGGENGFNQAIELSAEILSNVKFIQEKKLIGKYFEEISQDTGKYVFGVEDTLKA 180
Query: 310 LEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLTI 369
LE+GA++TL++ E D R K + G +K +++ + ++
Sbjct: 181 LEMGAIETLIVWENLDINRYELKNSTTGEMVVKHFGKDQES--DTSNFHDSETNAELEVQ 238
Query: 370 EKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
EK + E + G +E ++ ++EG QF R FGG+G +LR+++
Sbjct: 239 EKMPLLEWFANEYKRFGCTLEFVTNKSQEGSQFCRGFGGIGGMLRYQL 286
>pir||E69086 cell division protein - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622770|gb|AAB86115.1| (AE000923)
cell division protein [Methanobacterium
thermoautotrophicum]
Length = 360
Score = 83.9 bits (204), Expect = 3e-15
Identities = 77/278 (27%), Positives = 124/278 (43%), Gaps = 69/278 (24%)
Query: 145 LITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERIREQETHEFMKRIGE 204
++ +E + A +GL+R +E +T ++PGK R +R R + EF + I E
Sbjct: 146 ILVMEDDVAELGLIRQYGVEYRGPITGHIPGK--------RIQQRDRGKLRREFYESIVE 197
Query: 205 HANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYL---HHELKKKIIGVVDISYHGEYG 261
L + G+L+ II+ GPG K DF DYL + E+ KK + + + G G
Sbjct: 198 S-------LQKYGDLETIIIAGPGFYKSDFY--DYLMERYPEIAKKAV-LENTGTGGRAG 247
Query: 262 LRELVEKAS--DILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRALEIGAVDTLL 319
+ E++ K + + + + E + VNEFL+ + +D YG+ EV A+ +GAV+ LL
Sbjct: 248 ISEVLRKGTVERVSSEKRIASEIRNVNEFLEKLARDPDSVVYGKVEVMDAINMGAVEKLL 307
Query: 320 ISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLTIEKWDVAEELI 379
+ + + +S E+ E Y +
Sbjct: 308 VLD-------------------RVVSREDIEGY--------------------------L 322
Query: 380 KMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
M E G V +IS + E G+Q + GGL ILRFKI
Sbjct: 323 DMVESMGGSVVLISSEHEGGKQL-ESLGGLAGILRFKI 359
>pir||G75110 cell division protein pelota (pela) PAB0468 - Pyrococcus abyssi
(strain Orsay) >gi|5458111|emb|CAB49600.1| (AJ248285)
cell division protein PELOTA (PELA) [Pyrococcus abyssi]
Length = 356
Score = 81.1 bits (197), Expect = 2e-14
Identities = 77/294 (26%), Positives = 133/294 (45%), Gaps = 67/294 (22%)
Query: 129 VTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYE 188
+ E +E R K ++ +E EA + ++R ++ + + N+ GK RY
Sbjct: 124 IKEAVEASKRAKVM--IVAMEDGEAEVAIVREYGLDFIASIRHNIGGK---------RYN 172
Query: 189 RIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHH---ELK 245
RE E +F + + L+E+ ++ +IV GPG KE+F +L EL
Sbjct: 173 VKREDEEKKFFHDVA----KTIKDLIERENVQKVIVAGPGFYKENFY--GFLRENYPELA 226
Query: 246 KKIIGVVDISYHGEYGLRELVEKAS--DILRDHEVIREKKLVNEFLKHVVKDTGLATYGE 303
K++ + D S G G+ E++++ + + + V +E KLV + ++ + KD +A YG
Sbjct: 227 GKVV-LDDTSMGGRVGVYEVIKRGTVDKVYTETRVAQEIKLVEKVIERIAKDEPVA-YGL 284
Query: 304 REVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCG 363
++V A+ GAVDTLL+ + E LK E
Sbjct: 285 KDVEEAVNYGAVDTLLVLD----------------ELLKGDDRERI-------------- 314
Query: 364 SQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI 417
EE+++MA ++V ++S + E G + +A GG+ AILRFKI
Sbjct: 315 ------------EEIMEMARNLRANVVVVSSEHEGGDKL-KALGGIAAILRFKI 355
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.137 0.387
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 154861898
Number of Sequences: 2977
Number of extensions: 6726279
Number of successful extensions: 23514
Number of sequences better than 1.0e-10: 35
Number of HSP's better than 0.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 23388
Number of HSP's gapped (non-prelim): 40
length of query: 417
length of database: 189,106,746
effective HSP length: 58
effective length of query: 359
effective length of database: 154,394,500
effective search space: 55427625500
effective search space used: 55427625500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)