BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0407 (top6B) DE:DNA topoisomerase VI, subunit B (top6B)
(564 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75179 DNA topoisomerase VI, chain B (top6b) PAB0407 - Pyro... 1122 0.0
pir||D71034 probable typeII DNA topoisomerase subunit B - Pyroco... 1055 0.0
sp|O27088|TP6B_METTH TYPE II DNA TOPOISOMERASE VI SUBUNIT B >gi|... 446 e-124
gi|11498260 DNA topoisomerase VI, subunit B (top6B) [Archaeoglob... 392 e-108
pir||B72660 probable type II DNA topoisomerase VI subunit b APE0... 330 3e-89
sp|Q58434|TP6B_METJA TYPE II DNA TOPOISOMERASE VI SUBUNIT B >gi|... 324 1e-87
gb|AAK41242.1| DNA topoisomerase VI subunit B (top6B) [Sulfolobu... 317 1e-85
sp|O05207|TP6B_SULSH TYPE II DNA TOPOISOMERASE VI SUBUNIT B >gi|... 315 7e-85
gb|AAG19327.1| (AE005027) DNA topoisomerase VI subunit B; Top6B ... 197 3e-49
dbj|BAB02486.1| (AB025629) DNA topoisomerase VI subunit B-like p... 153 6e-36
>pir||E75179 DNA topoisomerase VI, chain B (top6b) PAB0407 - Pyrococcus abyssi
(strain Orsay) >gi|5458026|emb|CAB49516.1| (AJ248284)
DNA topoisomerase VI, subunit B (top6B) [Pyrococcus
abyssi]
Length = 564
Score = 1122 bits (2871), Expect = 0.0
Identities = 564/564 (100%), Positives = 564/564 (100%)
Query: 1 MAEARDLFKEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYI 60
MAEARDLFKEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYI
Sbjct: 1 MAEARDLFKEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYI 60
Query: 61 RVEIEELGKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVM 120
RVEIEELGKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVM
Sbjct: 61 RVEIEELGKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVM 120
Query: 121 FAQITSGKATRVITSTGGEIVEAWVKIDVQKNEGKIVKKLKHPNPKGWRGTRIELEVKDV 180
FAQITSGKATRVITSTGGEIVEAWVKIDVQKNEGKIVKKLKHPNPKGWRGTRIELEVKDV
Sbjct: 121 FAQITSGKATRVITSTGGEIVEAWVKIDVQKNEGKIVKKLKHPNPKGWRGTRIELEVKDV 180
Query: 181 KYVRSKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVMV 240
KYVRSKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVMV
Sbjct: 181 KYVRSKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVMV 240
Query: 241 DDVYTMAHRSKRSSVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEKL 300
DDVYTMAHRSKRSSVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEKL
Sbjct: 241 DDVYTMAHRSKRSSVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEKL 300
Query: 301 VSGDVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMKFLAPPTHGLR 360
VSGDVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMKFLAPPTHGLR
Sbjct: 301 VSGDVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMKFLAPPTHGLR 360
Query: 361 PIGEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLAYGGQIQGSEILRYANRV 420
PIGEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLAYGGQIQGSEILRYANRV
Sbjct: 361 PIGEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLAYGGQIQGSEILRYANRV 420
Query: 421 PLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNVVSVHVPYTSTGKQSIADIDEI 480
PLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNVVSVHVPYTSTGKQSIADIDEI
Sbjct: 421 PLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNVVSVHVPYTSTGKQSIADIDEI 480
Query: 481 HNEIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLEKYLPEIARSLHILTGEPEEKIKEY 540
HNEIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLEKYLPEIARSLHILTGEPEEKIKEY
Sbjct: 481 HNEIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLEKYLPEIARSLHILTGEPEEKIKEY 540
Query: 541 FLKLIESKIEVEEVSEVEAEEAEA 564
FLKLIESKIEVEEVSEVEAEEAEA
Sbjct: 541 FLKLIESKIEVEEVSEVEAEEAEA 564
>pir||D71034 probable typeII DNA topoisomerase subunit B - Pyrococcus horikoshii
>gi|3257993|dbj|BAA30676.1| (AP000006) 564aa long
hypothetical typeII DNA topoisomerase subunit B
[Pyrococcus horikoshii]
Length = 564
Score = 1055 bits (2699), Expect = 0.0
Identities = 518/564 (91%), Positives = 551/564 (96%)
Query: 1 MAEARDLFKEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYI 60
MAEA+DLFKEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILP I
Sbjct: 1 MAEAKDLFKEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPTI 60
Query: 61 RVEIEELGKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVM 120
RVEIEELGKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVM
Sbjct: 61 RVEIEELGKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVM 120
Query: 121 FAQITSGKATRVITSTGGEIVEAWVKIDVQKNEGKIVKKLKHPNPKGWRGTRIELEVKDV 180
FAQIT+GK TRVITSTGGEIVEAWVKIDVQKNEGKIVKK+KHPNPKGWRGTRIE+EVKDV
Sbjct: 121 FAQITTGKPTRVITSTGGEIVEAWVKIDVQKNEGKIVKKVKHPNPKGWRGTRIEMEVKDV 180
Query: 181 KYVRSKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVMV 240
KYVRS+QGVYWYLKLTAIANPHA+IELVEPDGKLVVFPRSSE+IP+PPVEMKPHPKGVMV
Sbjct: 181 KYVRSRQGVYWYLKLTAIANPHAYIELVEPDGKLVVFPRSSEEIPKPPVEMKPHPKGVMV 240
Query: 241 DDVYTMAHRSKRSSVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEKL 300
DDVYTMAHRSKRSSV+RFLVSEFSRIS+KK++ELIKY+ A+RL+KSE N+E+KEKL EKL
Sbjct: 241 DDVYTMAHRSKRSSVKRFLVSEFSRISEKKIEELIKYVAAIRLLKSEQNEEIKEKLREKL 300
Query: 301 VSGDVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMKFLAPPTHGLR 360
++GDVDSVLR+FGRKWKKE+EKVAKIM+K PEKLTW EAEEIVEAFKLMKFLAPPTHGLR
Sbjct: 301 INGDVDSVLRSFGRKWKKEVEKVAKIMEKPPEKLTWQEAEEIVEAFKLMKFLAPPTHGLR 360
Query: 361 PIGEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLAYGGQIQGSEILRYANRV 420
PIGEENIK+GLT ILKPEFVTAVTR+P+VYAGGIPFQVEVGLAYGGQI GSEILRYANRV
Sbjct: 361 PIGEENIKRGLTGILKPEFVTAVTRSPKVYAGGIPFQVEVGLAYGGQISGSEILRYANRV 420
Query: 421 PLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNVVSVHVPYTSTGKQSIADIDEI 480
PLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNV+SVHVPYTSTGKQSIADI+EI
Sbjct: 421 PLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNVISVHVPYTSTGKQSIADIEEI 480
Query: 481 HNEIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLEKYLPEIARSLHILTGEPEEKIKEY 540
+NEIRLALMDAAR+L+ YLGGK+RRMYQ+KRRKTLEKYLPEIARSLHILTGEPEEKI+EY
Sbjct: 481 YNEIRLALMDAARKLALYLGGKYRRMYQIKRRKTLEKYLPEIARSLHILTGEPEEKIREY 540
Query: 541 FLKLIESKIEVEEVSEVEAEEAEA 564
FLKLIESKIEVEEV VE EEAEA
Sbjct: 541 FLKLIESKIEVEEVESVEVEEAEA 564
>sp|O27088|TP6B_METTH TYPE II DNA TOPOISOMERASE VI SUBUNIT B >gi|7450845|pir||C69001
conserved hypothetical protein MTH1007 -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2622108|gb|AAB85503.1| (AE000873) conserved protein
[Methanobacterium thermoautotrophicum]
Length = 523
Score = 446 bits (1135), Expect = e-124
Identities = 255/549 (46%), Positives = 333/549 (60%), Gaps = 60/549 (10%)
Query: 3 EARDLFKE-FKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYIR 61
+A DLF E F+ + SEFFR+N MLG+TGKIRSLT + HE +TNS DA EEAGILP I+
Sbjct: 4 QALDLFDEGFQELTPSEFFRKNKQMLGFTGKIRSLTIVFHELITNSFDAAEEAGILPEIK 63
Query: 62 VEIEELGKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMF 121
++++ +GK+HY + +DNGPGIPE+YIP VF M AG+K RNIQSRGQQG+G SG V+
Sbjct: 64 IDLKRIGKDHYILRHQDNGPGIPEKYIPKVFCTMFAGSK-FRNIQSRGQQGLGCSGCVLL 122
Query: 122 AQITSGKATRVITST--GGEI--VEAWVKIDVQKNEGKIVKKLKHPNPKGWRGTRIELEV 177
+Q+T+GK +VI+ T GE+ V+ +K+DV+KN+G I++K + G G IEL
Sbjct: 123 SQMTTGKPVKVISGTMENGELKGVKMTLKMDVKKNQGLILEK-EEVEVDG-TGVCIELHF 180
Query: 178 KDVKYVRSKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKG 237
KDV Y S+QG Y Y++ T IANPHA I +P G VF R+S+ IP P E+ PHP G
Sbjct: 181 KDVSYSLSEQGAYEYIRRTMIANPHARIVFNDPTGNRYVFNRASDVIPPMPKEVLPHPWG 240
Query: 238 VMVDDVYTMAHRSKRSSVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLY 297
V DD+ MA + + L S SR+S K+ EL
Sbjct: 241 VTADDLIFMAKHTDKRRFGSMLKSNLSRMSSMKIKEL----------------------- 277
Query: 298 EKLVSGDVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMKFLAPPTH 357
E+L D ++K P+ + W EAE+IVEAFK MKF++PPT
Sbjct: 278 EELTGID----------------------LNKRPKDMKWEEAEQIVEAFKKMKFMSPPTS 315
Query: 358 GLRPIGEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLAYGGQI-------QG 410
GL PIGEE I KG+ IL+PEF VTR P+ Y GGI F VE G+AYGG +
Sbjct: 316 GLIPIGEEQIDKGMKEILQPEFTATVTRKPKTYRGGIAFIVEAGIAYGGNSGRLVGDQRK 375
Query: 411 SEILRYANRVPLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNVVSVHVPYTSTG 470
+EI+R+ANRVPL FDAGSC IT V+S+DWKRY I ++AP+ + VNVVS +VPY STG
Sbjct: 376 AEIMRFANRVPLTFDAGSCAITEGVKSLDWKRYGIRDLENAPISIFVNVVSTNVPYLSTG 435
Query: 471 KQSIADIDEIHNEIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLEKYLPEIARSLHILT 530
KQS++ EI EIR A M AR+L YL K + +R K E Y+P I + +L
Sbjct: 436 KQSVSPEPEILGEIRQATMIVARKLHKYLRKKKAAKEEAQRAKIFESYVPVIIKQAALLA 495
Query: 531 GEPEEKIKE 539
E +E
Sbjct: 496 EREEPDYRE 504
>gi|11498260 DNA topoisomerase VI, subunit B (top6B) [Archaeoglobus fulgidus]
>gi|3122957|sp|O29605|TP6B_ARCFU TYPE II DNA
TOPOISOMERASE VI SUBUNIT B >gi|7450846|pir||D69331
probable DNA topoisomerase VI chain B - Archaeoglobus
fulgidus >gi|2649967|gb|AAB90588.1| (AE001060) DNA
topoisomerase VI, subunit B (top6B) [Archaeoglobus
fulgidus]
Length = 602
Score = 392 bits (997), Expect = e-108
Identities = 227/534 (42%), Positives = 323/534 (59%), Gaps = 65/534 (12%)
Query: 15 SVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYIRVEIEELGKEHYKV 74
SV+EFF +N +LGY+ +++ T++ EAV N+LDACEEAGILP I V I ++ +H+K+
Sbjct: 9 SVAEFFEKNKHILGYSNPAKAIITVVKEAVDNALDACEEAGILPDIFVRISKVD-DHFKI 67
Query: 75 IVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMFAQITSGKATRVIT 134
+VEDNGPGIP E IP VFGK+L G++ H QSRGQQGIGIS AV++AQ+T+GK VI+
Sbjct: 68 VVEDNGPGIPREQIPKVFGKLLYGSRFHEIRQSRGQQGIGISAAVLYAQLTTGKPATVIS 127
Query: 135 STGGE--IVEAWVKIDVQKNEGKIVKKLKHPNPKGW---RGTRIELEVKDVKYVRS-KQG 188
T E + + I+ +KNE +IV++ + W GT+IELEV YVR KQ
Sbjct: 128 KTPDEDRAKKVVLYINTKKNEPEIVEE----GEEEWYLPSGTKIELEVAG-NYVRERKQS 182
Query: 189 VYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVMVDDVYTMAH 248
VY YL+ T++ NPHA I VEPDG + F R ++DIP+PP +KPHP G+ + + +M
Sbjct: 183 VYEYLRETSVINPHAKITFVEPDGTINEFKRVTDDIPQPPKSIKPHPHGIELGTLMSMLK 242
Query: 249 RSKRSSVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEKLVSGDVDSV 308
++ +++RRFL EF R+ +K D++
Sbjct: 243 STRATTLRRFLKEEFVRVGEKIADDV---------------------------------- 268
Query: 309 LRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMKFLAPPTHGLRPIGEENIK 368
L K D++P+++ +A +++ AF+ FL PPT L PIGE I
Sbjct: 269 -----------LRKAGFSGDETPQEMGRDDAAKLLNAFRQTDFLPPPTDCLSPIGEAMIA 317
Query: 369 KGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLAYGGQIQGSEI--LRYANRVPLLFDA 426
K L + +PEFV AVTR P+VY+G PF VEVGLAYGG+I+ ++ LRYAN++PLL+
Sbjct: 318 KSLMAEFQPEFVYAVTRKPKVYSGH-PFLVEVGLAYGGEIKSEKVTLLRYANKIPLLYQQ 376
Query: 427 GSCVITSAVRSIDWKRYKI----DSFDSAPLVVLVNVVSVHVPYTSTGKQSIADIDEIHN 482
G C +T AV S++WK Y + SAP V+L+++ S ++PYTS K+S+A I EI +
Sbjct: 377 GGCALTKAVESVNWKSYGMVQNRGELPSAPAVILIHLASTNIPYTSESKESVAAIPEIID 436
Query: 483 EIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLEKYLPEIARSL-HILTGEPEE 535
E RLAL + RRL YL K R+ + K+ + + K LP IA+ + IL EP E
Sbjct: 437 ETRLALQEVGRRLKEYLERKSRQQKKKKKEEMIGKVLPLIAKKVCEILEKEPLE 490
>pir||B72660 probable type II DNA topoisomerase VI subunit b APE0706 - Aeropyrum
pernix (strain K1) >gi|5104367|dbj|BAA79682.1|
(AP000060) 565aa long hypothetical type II DNA
topoisomerase VI subunit b [Aeropyrum pernix]
Length = 565
Score = 330 bits (836), Expect = 3e-89
Identities = 203/578 (35%), Positives = 316/578 (54%), Gaps = 69/578 (11%)
Query: 9 KEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYIRVEIEEL- 67
++++ SV+EFF +N + G+ R+L I E V NSLDA + GILP+I + I ++
Sbjct: 23 EKYREMSVAEFFAKNKELAGFANPTRALYQTIRELVENSLDATDAKGILPWIHISIRQIE 82
Query: 68 ------GKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMF 121
G+ Y V VEDNG G+P + FGK+L +K + Q+RG G+G+ A+++
Sbjct: 83 GSEGRGGRPRYTVTVEDNGIGVPVTSMAMAFGKVLFSSK-YVIRQTRGMYGLGVKAAILY 141
Query: 122 AQITSGKATRVITSTGGEIVEAWVK--IDVQKNEGKIVKKLKHPNPKGWRGTRIELEVKD 179
Q+T+G V ++T G +K IDVQ+NE +I+++ + W GTR+ L ++
Sbjct: 142 GQMTAGTPVEVYSATKGSQYVYMMKLVIDVQRNEPRILERGEWNKRGSWHGTRVTLSLEG 201
Query: 180 VKYVRSKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVM 239
+ R+K + Y+K TA+ P+A I L PDG++ FPRS+ +P+PP E KPHP GV
Sbjct: 202 -DWSRAKSKILEYIKRTAVIAPYAEIILETPDGEIYYFPRSTRKLPKPPRESKPHPHGVD 260
Query: 240 VDDVYTMAHRSKRSSVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEK 299
++ + +M ++ S++R FLV EF I DK + ++ K + ++K +
Sbjct: 261 IEQLKSMLRSTRASTLREFLVKEFQSIGDKTAQDFLE--------KYGLDPDLKPR---- 308
Query: 300 LVSGDVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMKFLAPPTHGL 359
+++ K +KL A+ ++E F AP + L
Sbjct: 309 -------------------------ELLKKGRDKLLRRLADALME----YPFRAPKSDYL 339
Query: 360 RPIGEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLAYGGQIQGSE---ILRY 416
PIG + I+ GL + PE+V AV+R+P+ Y G PF VEVG+AYGG I+ +LRY
Sbjct: 340 SPIGSDIIEIGLRRMFNPEWVGAVSRSPKAYRGH-PFIVEVGIAYGGGIEARSEPLLLRY 398
Query: 417 ANRVPLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNVVSVHVPYTSTGKQSIAD 476
AN++PLL++ V V SI+W++Y +D APLVVLV++ S VPY GK+S++D
Sbjct: 399 ANKIPLLYEEREDVSYKVVSSINWRQYNVDF--PAPLVVLVHIASTKVPYKGVGKESVSD 456
Query: 477 IDEIHNEIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLEKYLPEIARSLHILTGEPE-- 534
+ EI EIR A+ + ARRL YL K R ++R TL KY+PE+A SL P
Sbjct: 457 VPEIEAEIRNAVQEVARRLRLYLSRKAREEEAIRRSVTLAKYIPEVAVSLAYFLRPPSKW 516
Query: 535 --------EKIKEYFLKLIESKIEVEEVSEVEAEEAEA 564
+KI+E +K++ IE+ V + + E+ EA
Sbjct: 517 QPPKPEEVKKIQEALIKIVARHIELPPV-DGKTEDPEA 553
>sp|Q58434|TP6B_METJA TYPE II DNA TOPOISOMERASE VI SUBUNIT B >gi|2128638|pir||C64428
hypothetical protein MJ1028 - Methanococcus jannaschii
>gi|1591683|gb|AAB99032.1| (U67545) DNA topoisomerase
VI, subunit B (top6B) [Methanococcus jannaschii]
Length = 686
Score = 324 bits (822), Expect = 1e-87
Identities = 181/366 (49%), Positives = 240/366 (65%), Gaps = 13/366 (3%)
Query: 6 DLFKEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYIRVEIE 65
+LFKEFK SV+EFFR+N MLGY+GKIRSLTTIIHE VTNSLDACEEAGILP I+VEIE
Sbjct: 34 ELFKEFKEHSVAEFFRKNKHMLGYSGKIRSLTTIIHELVTNSLDACEEAGILPDIKVEIE 93
Query: 66 ELGKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMFAQIT 125
+LG +HYKV VEDNGPGIP E+IP VFGKMLAG+K HR IQSRGQQGIG +G ++F+QIT
Sbjct: 94 KLGADHYKVAVEDNGPGIPLEFIPKVFGKMLAGSKMHRFIQSRGQQGIGAAGVLLFSQIT 153
Query: 126 SGKATRVITSTG-GEIVEAWVKIDVQKNEGKIVKKLKHPNPKGWRGTRIELEVKDVKYVR 184
+GK ++ITSTG G I E VK++V+KNEG+IV K WRGTR+E E K+V Y R
Sbjct: 154 TGKPLKIITSTGDGNIYEVEVKMNVEKNEGEIVSKKVRKGK--WRGTRVEGEFKEVSYNR 211
Query: 185 SKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVMVDDVY 244
+ G + YL+ ++A PHA I L +P G+ VVF R ++P+ P EMKPHP G+ D++
Sbjct: 212 GEFGPFEYLRRISLATPHAKIVLKDPYGE-VVFDRVVNELPKKPEEMKPHPYGLTTDELL 270
Query: 245 TMAHRSKRSSVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEKLVSGD 304
+A ++K V LVSE SR++ K++ ELI Y+ ++K + + ++ D
Sbjct: 271 YIARKTKSKKVSSMLVSELSRVTTKRIKELINYMLRDLILKKFKDSVFWNMVVSCYLNID 330
Query: 305 VDSVLRAF-GRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMKFLAPPTHGLRPIG 363
++S L F E+E V ++ PE L E + + M++L +
Sbjct: 331 IESYLNKFKDYITDDEIETVRMLIKNLPESL--DELKRYALKYITMEYL------FNKLS 382
Query: 364 EENIKK 369
EE I K
Sbjct: 383 EEEINK 388
Score = 221 bits (558), Expect = 1e-56
Identities = 142/394 (36%), Positives = 228/394 (57%), Gaps = 28/394 (7%)
Query: 173 IELEVKDVKYVRSKQGVYWYLKLTAIANPHAHIELVE-----PDGKLVVFPRSSEDIPEP 227
I ++D+ + K V+W + ++ N L + D ++ +++PE
Sbjct: 301 INYMLRDLILKKFKDSVFWNMVVSCYLNIDIESYLNKFKDYITDDEIETVRMLIKNLPES 360
Query: 228 PVEMKPHP-KGVMVDDVYTMAHRSKRSSVRRFLVSEFSRISDKKVDELIK-YITALRLIK 285
E+K + K + ++ ++ + + ++ + F +I + ++ K Y++A +
Sbjct: 361 LDELKRYALKYITMEYLFNKLSEEEINKLK----NHFKKIPENFMEWAEKNYLSAT--VV 414
Query: 286 SETNKEVKE--KLYEKLVSGDVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIV 343
E NK+VK K E+ ++ ++ + + KK ++V I++K+P++LTW EAE IV
Sbjct: 415 DELNKKVKNIVKNPEEFIA-EIKNKGLISDEELKKFEDEVKSILNKNPKELTWDEAEMIV 473
Query: 344 EAFKLMKFLAPPTHGLRPIGEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLA 403
+ M+F+APPT GLRPIG ENI+K L +L+P+FV A+TR P+ Y GGIPF VEV +A
Sbjct: 474 NCLQSMEFMAPPTTGLRPIGAENIEKSLKELLQPDFVKAITRNPKTYKGGIPFAVEVAIA 533
Query: 404 YGGQI--QGS-----EILRYANRVPLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVL 456
YGG QG EI+R+AN VPLL+DA +C +T AV+SI+WKRY + D AP+ V
Sbjct: 534 YGGNAGRQGDEGRRMEIMRFANHVPLLYDASACGLTKAVKSINWKRYGLRGED-APITVF 592
Query: 457 VNVVSVHVPYTSTGKQSIA----DIDEIHNEIRLALMDAARRLSFYLGGKFRRMYQVKRR 512
VN++S +PYTS GKQ++A + +EI+NEIR ALM R L YL R + K+R
Sbjct: 593 VNLISTFIPYTSAGKQAVACSENENEEIYNEIRHALMICGRELEKYLSRIRREAEEEKKR 652
Query: 513 KTLEKYLPEIARSLHILTGEPEEKIKEYFLKLIE 546
K + KY A +L + +P ++I+E +KL+E
Sbjct: 653 KYVMKYARIFAEALANILNKPVDEIEEKVVKLLE 686
>gb|AAK41242.1| DNA topoisomerase VI subunit B (top6B) [Sulfolobus solfataricus]
Length = 530
Score = 317 bits (805), Expect = 1e-85
Identities = 196/565 (34%), Positives = 304/565 (53%), Gaps = 66/565 (11%)
Query: 9 KEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYIRVEIEEL- 67
++F S +EFF+RN + G+ R+L + E + NSLDA + GILP I++ I+ +
Sbjct: 5 EKFASLSPAEFFKRNPELAGFPNPARALYQTVRELIENSLDATDVHGILPNIKITIDLID 64
Query: 68 -GKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMFAQITS 126
++ YKV V DNG GIP + +P+ FG++L +K + N Q+RG G+G+ AV+++Q+
Sbjct: 65 ESRQIYKVNVVDNGIGIPPQEVPNAFGRVLYSSK-YVNRQTRGMYGLGVKAAVLYSQMHQ 123
Query: 127 GKATRVITS--TGGEIVEAWVKIDVQKNEGKIVKKLKHPNPKGWRGTRIELEVKDVKYVR 184
K + TS + +KID+ KNE IV++ N G+ GT + + + + +
Sbjct: 124 DKPIEIETSPVNSKRLYTFKLKIDINKNEPIIVERGSVENNTGFHGTSVAISIPG-DWPK 182
Query: 185 SKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVMVDDVY 244
+K +Y Y+K T I P+A +P+G + +PR + IP+PP E+KPHP GV +++
Sbjct: 183 AKSRIYEYIKRTYIITPYAEFIFKDPEGNVTYYPRLTNKIPKPPQEVKPHPYGVDREEIK 242
Query: 245 TMAHRSKRS-SVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEKLVSG 303
M + KR +++ FL+SEF I D D++ L L+ NK+VK
Sbjct: 243 IMINNLKRDYTIKEFLMSEFQSIGDTTADKI------LELVGLRPNKKVK---------- 286
Query: 304 DVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMK-FLAPPTHGLRPI 362
LT E +VE FK + F +P L I
Sbjct: 287 -----------------------------NLTEEEITRLVETFKKYEDFRSPSADSLSVI 317
Query: 363 GEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLAYGGQIQGSE---ILRYANR 419
GE+ I+ GL I P+F ++TR P+ Y G PF VE G+A+GG I E +LRYAN+
Sbjct: 318 GEDLIELGLKKIFNPDFTASITRKPKAYQGH-PFIVEAGIAFGGSIPVGEEPIVLRYANK 376
Query: 420 VPLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNVVSVHVPYTSTGKQSIADIDE 479
+PL++D S VI V +DWKRY I+S D +VV+V++ S +PY S GK+SIA++++
Sbjct: 377 IPLIYDEKSDVIWKVVEELDWKRYGIES-DQYQMVVMVHLCSTKIPYKSAGKESIAEVED 435
Query: 480 IHNEIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLEKYLPEIARSLHI--------LTG 531
I EI+ ALM+ AR+L YL K + K+ KY+PE++RSL I L
Sbjct: 436 IEKEIKNALMEVARKLKLYLSEKRKEQEAKKKLLAYLKYVPEVSRSLAIFLASGNKELVP 495
Query: 532 EPEEKIKEYFLKLIESKIEVEEVSE 556
+ + +I E KLI K+++ + E
Sbjct: 496 KYQGEIVEGLFKLISKKLDLINIEE 520
>sp|O05207|TP6B_SULSH TYPE II DNA TOPOISOMERASE VI SUBUNIT B >gi|1926403|emb|CAA71604.1|
(Y10582) type II DNA topoisomerase subunit B [Sulfolobus
shibatae]
Length = 530
Score = 315 bits (799), Expect = 7e-85
Identities = 195/565 (34%), Positives = 303/565 (53%), Gaps = 66/565 (11%)
Query: 9 KEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYIRVEIEEL- 67
++F S +EFF+RN + G+ R+L + E + NSLDA + GILP I++ I+ +
Sbjct: 5 EKFTSLSPAEFFKRNPELAGFPNPARALYQTVRELIENSLDATDVHGILPNIKITIDLID 64
Query: 68 -GKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMFAQITS 126
++ YKV V DNG GIP + +P+ FG++L +K + N Q+RG G+G+ AV+++Q+
Sbjct: 65 DARQIYKVNVVDNGIGIPPQEVPNAFGRVLYSSK-YVNRQTRGMYGLGVKAAVLYSQMHQ 123
Query: 127 GKATRVITS--TGGEIVEAWVKIDVQKNEGKIVKKLKHPNPKGWRGTRIELEVKDVKYVR 184
K + TS I +KID+ KNE IV++ N +G+ GT + + + + +
Sbjct: 124 DKPIEIETSPVNSKRIYTFKLKIDINKNEPIIVERGSVENTRGFHGTSVAISIPG-DWPK 182
Query: 185 SKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVMVDDVY 244
+K +Y Y+K T I P+A +P+G + +PR + IP+PP E+KPHP GV +++
Sbjct: 183 AKSRIYEYIKRTYIITPYAEFIFKDPEGNVTYYPRLTNKIPKPPQEVKPHPYGVDREEIK 242
Query: 245 TMAHRSKRS-SVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEKLVSG 303
+ + KR +++ FLV+EF I D D++ L L + NK+VK
Sbjct: 243 ILINNLKRDYTIKEFLVNEFQSIGDTTADKI------LELAGLKPNKKVK---------- 286
Query: 304 DVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMK-FLAPPTHGLRPI 362
LT E +VE FK + F +P L I
Sbjct: 287 -----------------------------NLTEEEITRLVETFKKDEDFRSPSADSLSVI 317
Query: 363 GEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQVEVGLAYGGQIQGSE---ILRYANR 419
GE+ I+ GL I P+F ++TR P+ Y G PF VE G+A+GG I E +LRYAN+
Sbjct: 318 GEDLIELGLKKIFNPDFAASITRKPKAYQGH-PFIVEAGVAFGGSIPVGEEPIVLRYANK 376
Query: 420 VPLLFDAGSCVITSAVRSIDWKRYKIDSFDSAPLVVLVNVVSVHVPYTSTGKQSIADIDE 479
+PL++D S VI V +DWKRY I+S D +VV+V++ S +PY S GK+SIA+++
Sbjct: 377 IPLIYDEKSDVIWKVVEELDWKRYGIES-DQYQMVVMVHLCSTKIPYKSAGKESIAEVEN 435
Query: 480 IHNEIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLEKYLPEIARSLHI--------LTG 531
I EI+ ALM+ AR+L YL K + K+ KY+PE++RSL L
Sbjct: 436 IEKEIKNALMEVARKLKQYLSEKRKEQEAKKKLLAYLKYIPEVSRSLATFLASGNKELVS 495
Query: 532 EPEEKIKEYFLKLIESKIEVEEVSE 556
+ + +I E KLI K+++ + E
Sbjct: 496 KYQNEISEGLFKLISKKLDLINIEE 520
>gb|AAG19327.1| (AE005027) DNA topoisomerase VI subunit B; Top6B [Halobacterium sp.
NRC-1]
Length = 804
Score = 197 bits (495), Expect = 3e-49
Identities = 118/278 (42%), Positives = 164/278 (58%), Gaps = 9/278 (3%)
Query: 4 ARDLFKEFKVQSVSEFFRRNAAMLGYTGKIRSLTTIIHEAVTNSLDACEEAGILPYIRVE 63
A +L + SV+EFF +N MLG+ R L T + EAV N+LDA EEAGILP I VE
Sbjct: 16 AEELAASQREISVAEFFEKNKHMLGFDSGARGLVTAVKEAVDNALDATEEAGILPDIYVE 75
Query: 64 IEELGKEHYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMFAQ 123
I E G+++Y +IVEDNGPGI IP +FGK+L G++ H QSRGQQGIGIS AV+++Q
Sbjct: 76 ISE-GRDYYTLIVEDNGPGITNAQIPKIFGKLLYGSRFHAREQSRGQQGIGISAAVLYSQ 134
Query: 124 ITSGKATRVITST-GGEIVEAW-VKIDVQKNEGKIVKKLK----HPNPKGWRGTRIELEV 177
+TSGK R+ + T E + + ID NE +I + + + +G GTRIE+ +
Sbjct: 135 LTSGKPVRIESRTQDSETANVYELIIDTDTNEPEISAETEVSAAKSDLRGTHGTRIEMAL 194
Query: 178 KDVKYVRSKQGVYWYLKLTAIANPHAHIELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKG 237
+R++ ++ Y+K TA+ NPHA IEL EP G+L +P E+ PHP G
Sbjct: 195 D--ANMRARGQLHDYIKHTAVVNPHARIELQEPGGELKSERAEEASLPAETDEILPHPHG 252
Query: 238 VMVDDVYTMAHRSKRSSVRRFLVSEFSRISDKKVDELI 275
V + + M + SV FL SEF+R+ K +I
Sbjct: 253 VELGTLIKMLAETDSHSVSGFLQSEFTRVGSKTATGII 290
Score = 129 bits (320), Expect = 1e-28
Identities = 71/217 (32%), Positives = 118/217 (53%), Gaps = 9/217 (4%)
Query: 339 AEEIVEAFKLMKFLAPPTHGLRPIGEENIKKGLTSILKPEFVTAVTRAPRVYAGGIPFQV 398
A +++ A + +APPT L PI + ++ GL + +F A TR V+ GG PF V
Sbjct: 490 ASDLLAAMASVNVMAPPTSCLSPIEADQLEAGLRTEFDADFYAAATRDADVH-GGDPFIV 548
Query: 399 EVGLAYGGQIQ---GSEILRYANRVPLLFDAGSCVITSAVRSIDWKRYKIDS-----FDS 450
E G+AYGG I G +++R+ANRVPL++ G+C T + I W+ Y +
Sbjct: 549 EAGIAYGGDIDSEGGVQLMRFANRVPLVYQRGACATTDVLGDIGWRNYNLSQPGGSGLPQ 608
Query: 451 APLVVLVNVVSVHVPYTSTGKQSIADIDEIHNEIRLALMDAARRLSFYLGGKFRRMYQVK 510
P V++V+V S +VP+TS K +IA++ EI EI LA+ +AAR L +L + + +
Sbjct: 609 GPAVIMVHVASTNVPFTSESKDAIANVPEIEAEIELAVREAARELKSFLQKRQSMRKRQQ 668
Query: 511 RRKTLEKYLPEIARSLHILTGEPEEKIKEYFLKLIES 547
++ + LP +A + LTG + + +++ +
Sbjct: 669 KQDVIMDILPTMAEKVGELTGRGGVDVSDSLARIMNN 705
>dbj|BAB02486.1| (AB025629) DNA topoisomerase VI subunit B-like protein [Arabidopsis
thaliana]
Length = 694
Score = 153 bits (382), Expect = 6e-36
Identities = 126/508 (24%), Positives = 228/508 (44%), Gaps = 84/508 (16%)
Query: 71 HYKVIVEDNGPGIPEEYIPHVFGKMLAGTKAHRNIQSRGQQGIGISGAVMFAQITSGKAT 130
+YKV +DNG G+P + IP++FG++L+GTK Q+RG+ G+G A++++++++G
Sbjct: 153 YYKVTCKDNGKGMPHDDIPNMFGRVLSGTKYGLK-QTRGKFGLGAKMALIWSKMSTGLPI 211
Query: 131 RVITSTGGE--IVEAWVKIDVQKNEGKIVKKLKHPNPKGWRGTRIELEVKDVKYVRSKQG 188
+ +S + + + ID+ +N I K N + W G I++ ++ + +
Sbjct: 212 EISSSMKSQNYVTFCRLDIDIHRNIPHIHLHEKKGNKEKWHGAEIQVVIEG-NWTTYRSK 270
Query: 189 VYWYLKLTAIANPHAH-----IELVEPDGKLVVFPRSSEDIPEPPVEMKPHPKGVMVDDV 243
+ Y++ A+ P+A I + F R ++ +P P+E K HP V + +
Sbjct: 271 ILHYMRQMAVITPYAQFLFRFISETPEKNVTIKFTRRTDVMPPIPIETKHHPSSVDLLLI 330
Query: 244 YTMAHRSKRSSVRRFLVSEFSRISDKKVDELIKYITALRLIKSETNKEVKEKLYEKLVSG 303
+ + + ++ +FL +EF I+ LI E + + K V
Sbjct: 331 KRLITDTSKKTLLQFLQNEFVNINKTLAARLI----------GEMGPDFGPSMAVKSV-- 378
Query: 304 DVDSVLRAFGRKWKKELEKVAKIMDKSPEKLTWHEAEEIVEAFKLMKFLAPPTHGLRPIG 363
T + I + F+ KF P L P G
Sbjct: 379 -------------------------------TSQQMVRIHQLFRQAKFDDPSGDCLSPAG 407
Query: 364 EENIKKGLTSILKPEFVTAVTRAPRVYA-----------------------GGIPFQVEV 400
E N++ G+ L P+ V + + + G PF VE
Sbjct: 408 EYNLRLGIIKELHPDMVATYSGSFTYFVVNLSFVSSSVDFFLETMFSAQVFEGHPFIVEA 467
Query: 401 GLAYGGQI--QGSEILRYANRVPLLFDAGSCVIT-SAVRSIDWKRYKIDSFDSAPLVVLV 457
G++ GG+ QG I R+ANR+PLLF+ G+ V+T +A++ I+W YKI+ + V V
Sbjct: 468 GVSLGGRDVKQGINIFRFANRIPLLFEQGADVVTRTALKRINWNSYKINQTQD-KIGVFV 526
Query: 458 NVVSVHVPYTSTGKQSIA-DIDEIHNEIRLALMDAARRLSFYLGGKFRRMYQVKRRKTLE 516
++VS +P+ TGK+ I DI EI ++ A+ +L + + + Q +R+++L
Sbjct: 527 SIVSTKIPFKGTGKEYIGDDISEIATAVKSAIQQCCIQLKSKIVKRLQAREQQERKRSLS 586
Query: 517 KYLPE----IARSLHILTGEPEEKIKEY 540
+Y+P+ + L +T E + K K Y
Sbjct: 587 RYIPDATGAVYEVLKQMTEEHKTKRKRY 614
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.136 0.384
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 202789257
Number of Sequences: 2977
Number of extensions: 8818925
Number of successful extensions: 27175
Number of sequences better than 1.0e-10: 10
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 27109
Number of HSP's gapped (non-prelim): 19
length of query: 564
length of database: 189,106,746
effective HSP length: 60
effective length of query: 504
effective length of database: 153,197,526
effective search space: 77211553104
effective search space used: 77211553104
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 167 (69.5 bits)