BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0417 (psmA) DE:proteasome, subunit alpha (EC 3.4.99.46)
(psmA)
         (260 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||B75181 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   515  e-145
sp|O59219|PRCA_PYRHO PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN...   499  e-140
pir||T43887 proteasome alpha chain [imported] - Thermococcus sp ...   437  e-122
sp|Q60177|PRCA_METJA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN...   315  4e-85
sp|Q59565|PRCA_METTE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN...   300  1e-80
gi|11498101 proteasome, subunit alpha (psmA) [Archaeoglobus fulg...   292  2e-78
sp|O26782|PRCA_METTH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN...   291  6e-78
pir||T48678 proteasome alpha-1 chain [validated] - Haloferax vol...   242  4e-63
sp|Q9YC01|PRCA_AERPE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN...   231  8e-60
gi|7106389 proteasome (prosome, macropain) subunit, alpha type 7...   220  2e-56
gb|AAK41034.1| Proteasome subunit [Sulfolobus solfataricus]           219  3e-56
emb|CAB57565.1| (Y18930) proteasome alpha subunit (N-terminus) [...   219  3e-56
sp|P48004|PRC6_RAT PROTEASOME SUBUNIT RC6-1 (MULTICATALYTIC ENDO...   218  5e-56
dbj|BAA89276.1| (AB027707) alpha 4 subunit of 20S proteasome [Ca...   218  6e-56
sp|P25156|PRCA_THEAC PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN...   218  6e-56
gi|4506189 proteasome (prosome, macropain) subunit, alpha type, ...   217  8e-56
gb|AAG18783.1| (AE004983) proteasome, subunit beta; PsmB [Haloba...   217  1e-55
gb|AAC99402.1| (AF054185) proteasome subunit HSPC [Homo sapiens]      216  2e-55
sp|O04861|PRC6_ORYSA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN...   214  9e-55
dbj|BAA86962.1| (AB004782) 20S proteasome alpha 4 subunit [Xenop...   213  2e-54
dbj|BAA86956.1| (AB027463) 20S proteasome alpha 4 subunit [Xenop...   213  2e-54
pir||JC5510 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   212  3e-54
dbj|BAA76428.1| (AB025000) multicatalytic endopeptidase complex ...   211  8e-54
sp|P30186|PRC6_ARATH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN...   210  1e-53
gb|AAC32059.1| (AF043523) 20S proteasome subunit PAD2 [Arabidops...   209  2e-53
sp|O24030|PRC6_LYCES PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN...   208  7e-53
emb|CAA73622.1| (Y13179) multicatalytic endopeptidase [Arabidops...   207  9e-53
sp|P52427|PRC9_SPIOL PROTEASOME 27 KD SUBUNIT (MULTICATALYTIC EN...   206  2e-52
dbj|BAA99540.1| (AB032061) alpha 4 subunit of 20S proteasome [Or...   206  3e-52
emb|CAA67761.1| (X99382) alpha proteasome [Entamoeba histolytica]     205  3e-52
emb|CAB86711.1| (AL163505) 20S proteasome alpha 5 subunit [Leish...   205  3e-52
gb|AAC32057.1| (AF043521) 20S proteasome subunit PAC1 [Arabidops...   203  1e-51
gb|AAC35982.1| (AF088914) proteasome alpha subunit [Petunia x hy...   203  1e-51
emb|CAA73624.1| (Y13181) multicatalytic endopeptidase [Arabidops...   202  4e-51
sp|P34120|PRC6_DICDI PROTEASOME SUBUNIT DD5 (MULTICATALYTIC ENDO...   201  5e-51
pir||T48679 proteasome alpha-2 chain [validated] - Haloferax vol...   201  7e-51
gb|AAC32061.1| (AF043525) 20S proteasome subunit PAE2 [Arabidops...   199  3e-50
dbj|BAA95822.1| (AP002069) ESTs AU058081(E3082),AU075427(E30384)...   199  3e-50
gb|AAD31877.1|AF140353_1 (AF140353) 20S proteasome alpha 5 subun...   199  3e-50
dbj|BAA96832.1| (AB026561) alpha 5 subunit of 20S proteasome [Or...   199  3e-50
gb|AAF89684.1|AF169652_1 (AF169652) 20S proteasome alpha 4 subun...   198  4e-50
gb|AAC32060.1| (AF043524) 20S proteasome subunit PAE1 [Arabidops...   198  6e-50
dbj|BAA78755.1| (AB023482) ESTs AU058081(E30812),AU058365(E50679...   198  6e-50
pir||T19775 hypothetical protein C36B1.4 - Caenorhabditis elegan...   198  8e-50
gb|AAF34770.1|AF227625_1 (AF227625) proteasome 27 kDa subunit [E...   197  1e-49
gi|6321574 proteasome component Y13; Pre9p [Saccharomyces cerevi...   196  3e-49
gi|6324535 alpha-type of subunit of 20S proteasome; Pre6p [Sacch...   195  5e-49
gb|AAF70292.1|AF255338_1 (AF255338) 20S proteasome subunit [Glyc...   195  5e-49
pir||T38639 proteasome component PUP2 homolog - fission yeast  (...   192  3e-48
pdb|1G65|B Chain B, Crystal Structure Of Epoxomicin:20s Proteaso...   192  3e-48
pdb|1G0U|B Chain B, A Gated Channel Into The Proteasome Core Par...   192  3e-48
sp|Q10329|PRC6_SCHPO PUTATIVE PROTEASOME COMPONENT PRE6 (MACROPA...   191  8e-48
pdb|1G0U|C Chain C, A Gated Channel Into The Proteasome Core Par...   191  8e-48
pdb|1G65|C Chain C, Crystal Structure Of Epoxomicin:20s Proteaso...   190  1e-47
sp|Q09682|PRC9_SCHPO PUTATIVE PROTEASOME COMPONENT C9/Y13 (MACRO...   190  2e-47
gi|4506185 proteasome (prosome, macropain) subunit, alpha type, ...   189  2e-47
pir||S17521 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   189  3e-47
gi|7106387 proteasome (prosome, macropain) subunit, alpha type 5...   189  3e-47
gi|8394069 proteasome (prosome, macropain) subunit, alpha type 4...   189  4e-47
gi|6755196 proteasome (prosome, macropain) subunit, alpha type 4...   188  5e-47
sp|Q95083|PRCZ_DROME PROTEASOME PSMA5 SUBUNIT (MULTICATALYTIC EN...   188  7e-47
gb|AAF57875.1| (AE003803) ProsMA5 gene product [Drosophila melan...   187  9e-47
sp|O73672|PRC3_CARAU PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT ...   187  1e-46
pir||S38530 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   187  1e-46
gi|4506187 proteasome (prosome, macropain) subunit, alpha type, ...   187  1e-46
pir||T40971 20s proteasome component C3 - fission yeast  (Schizo...   186  2e-46
sp|P34119|PRC9_DICDI PROTEASOME SUBUNIT DD4 (MULTICATALYTIC ENDO...   186  3e-46
sp|P22769|PRC6_DROME PROTEASOME 28 KD SUBUNIT 1 (MULTICATALYTIC ...   185  6e-46
pir||S23451 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   184  7e-46
gi|4506181 proteasome (prosome, macropain) subunit, alpha type, ...   184  7e-46
sp|O23708|PRC3_ARATH PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT ...   184  7e-46
gi|11428206 proteasome (prosome, macropain) subunit, alpha type,...   184  7e-46
gi|8394063 proteasome (prosome, macropain) subunit, alpha type 2...   184  1e-45
gb|AAF05906.1|AF148125_1 (AF148125) 20S proteasome alpha 2 subun...   184  1e-45
emb|CAB62817.1| (AL133435) 20S proteasome alpha 2 subunit [Leish...   184  1e-45
gi|6679497 proteasome (prosome, macropain) subunit, alpha type 2...   183  1e-45
sp|P24495|PRC3_XENLA PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT ...   183  2e-45
gi|8394072 proteasome (prosome, macropain) subunit, alpha type 5...   183  2e-45
dbj|BAA96830.1| (AB026559) alpha 2 subunit of 20S proteasome [Or...   182  3e-45
gb|AAC34196.1| (AF017649) alpha4 proteasome subunit [Drosophila ...   182  4e-45
gb|AAF60416.1| (AC006708) contains similarity to Pfam family PF0...   179  2e-44
sp|P40301|PRC3_DROME PROTEASOME 25 KDA SUBUNIT (MULTICATALYTIC E...   179  3e-44
gb|AAF46651.1| (AE003452) Pros29 gene product [Drosophila melano...   179  3e-44
sp|P18053|PRC9_DROME PROTEASOME 29 KD SUBUNIT (MULTICATALYTIC EN...   177  1e-43
gi|6321692 Proteasome subunit; Pup2p [Saccharomyces cerevisiae] ...   174  8e-43
pdb|1G0U|D Chain D, A Gated Channel Into The Proteasome Core Par...   174  8e-43
emb|CAA46111.1| (X64918) PUP2 [Saccharomyces cerevisiae]              173  2e-42
emb|CAA74025.1| (Y13691) multicatalytic endopeptidase complex, p...   170  1e-41
dbj|BAB09993.1| (AB023031) multicatalytic endopeptidase complex ...   170  1e-41
pdb|1G65|D Chain D, Crystal Structure Of Epoxomicin:20s Proteaso...   169  3e-41
emb|CAB95217.1| (AL359773) proteasome subunit [Leishmania major]      169  3e-41
gb|AAC32054.1| (AF043518) 20S proteasome subunit PAA1 [Arabidops...   169  4e-41
gb|AAG28528.1|AF198387_1 (AF198387) 20S proteasome alpha 3 subun...   168  5e-41
pir||S72226 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   168  6e-41
gb|AAF47215.1| (AE003464) Pros28.1B gene product [Drosophila mel...   167  1e-40
pir||T02089 proteasome chain - rice >gi|2570505|gb|AAB82138.1| (...   167  1e-40
gb|AAF55802.1| (AE003731) Pros28.1A gene product [Drosophila mel...   166  2e-40
gb|AAB34631.1| Doa5, PUP2=alpha-type proteasome subunit zeta hom...   166  2e-40
pir||T21350 hypothetical protein F25H2.9 - Caenorhabditis elegan...   166  2e-40
emb|CAB39975.1| (Y16644) PRCI [Nicotiana tabacum]                     165  4e-40
pir||T06142 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   165  5e-40
gi|6323547 proteasome component Y7; Pre8p [Saccharomyces cerevis...   164  1e-39
gi|6324938 proteasome component YC1 (protease yscE subunit 1); P...   163  2e-39
gb|AAC32055.1| (AF043519) 20S proteasome subunit PAA2 [Arabidops...   162  3e-39
sp|Q27488|PRC3_CAEEL PROBABLE PROTEASOME COMPONENT C3 (MACROPAIN...   161  6e-39
sp|Q27563|PRC8_DICDI PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT ...   161  8e-39
pdb|1G65|F Chain F, Crystal Structure Of Epoxomicin:20s Proteaso...   161  1e-38
pdb|1G0U|F Chain F, A Gated Channel Into The Proteasome Core Par...   161  1e-38
dbj|BAA96829.1| (AB026558) alpha 1 subunit of 20S proteasome [Or...   160  1e-38
gb|AAF59183.1| (AE003839) Prosalpha1 gene product [alt 1] [Droso...   160  2e-38
pir||S72225 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   159  2e-38
gi|8394076 proteasome (prosome, macropain) subunit, alpha type 6...   159  3e-38
sp|P90513|PRC8_ACACA PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT ...   159  3e-38
gi|6755198 proteasome (prosome, macropain) subunit, alpha type 6...   158  5e-38
gb|AAD33944.1|AF144749_1 (AF144749) 20S proteasome subunit alpha...   158  7e-38
gi|8394066 proteasome (prosome, macropain) subunit, alpha type 3...   156  3e-37
gi|4506183 proteasome (prosome, macropain) subunit, alpha type, ...   155  6e-37
emb|CAA62960.1| (X91847) proteasome subunit C9-like protein [Sus...   154  8e-37
gi|6755194 proteasome (prosome, macropain) subunit, alpha type 3...   154  8e-37
sp|P34066|PRC2_ARATH PROTEASOME, 30 KD SUBUNIT (MULTICATALYTIC E...   152  5e-36
gb|AAC32062.1| (AF043526) 20S proteasome subunit PAF1 [Arabidops...   152  5e-36
gb|AAC32063.1| (AF043527) 20S proteasome subunit PAF2 [Arabidops...   152  5e-36
pir||T19320 hypothetical protein C15H11.7 - Caenorhabditis elega...   151  7e-36
sp|O24362|PRC8_SPIOL PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT ...   151  9e-36
pir||S38529 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   149  3e-35
gb|AAC23597.1| (AF070462) proteasome A type subunit [Cryptospori...   148  6e-35
gb|AAB48404.1| (U73851) 29 kDa proteasome subunit TCPR29 [Trypan...   148  8e-35
gb|AAB48403.1| (U73850) 29 kDa proteasome subunit TCPR29A [Trypa...   148  8e-35
pir||T41139 proteasome component c1 - fission yeast (Schizosacch...   147  1e-34
gb|AAC32064.1| (AF043528) 20S proteasome subunit PAG1 [Arabidops...   147  1e-34
emb|CAA73625.1| (Y13182) multicatalytic endopeptidase [Arabidops...   146  2e-34
dbj|BAA96833.1| (AB026562) alpha 7 subunit of 20S proteasome [Or...   145  7e-34
sp|O23715|PRC8_ARATH PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT ...   144  9e-34
gb|AAD52094.1|AF088882_1 (AF088882) 20S proteasome alpha subunit...   142  3e-33
emb|CAA10314.1| (AJ131148) proteasome subunit alpha-6 [Trypanoso...   141  8e-33
sp|P52428|PRC2_ORYSA PROTEASOME COMPONENT C2 (MACROPAIN SUBUNIT ...   141  1e-32
gb|AAC34197.1| (AF017650) testes-specific alpha4 proteasome subu...   140  1e-32
gb|AAF69728.1|AC068783_4 (AC068783) 26S Proteasome alpha subunit...   140  1e-32
gb|AAF58889.1| (AE003832) Prosalpha7 gene product [Drosophila me...   140  2e-32
pir||T40592 26s proteasome alpha subunit - fission yeast  (Schiz...   139  3e-32
gb|AAF89683.1|AF169651_1 (AF169651) 20S proteasome alpha 7 subun...   138  7e-32
gb|AAB03506.1| (U60168) PrtC [Dictyostelium discoideum]               136  2e-31
gb|AAC16604.1| (AF027978) 20S proteasome subunit C2 [Gallus gallus]   133  2e-30
pir||S64739 multicatalytic endopeptidase complex (EC 3.4.99.46) ...   132  4e-30
gb|AAG28527.1|AF198386_1 (AF198386) 20S proteasome alpha 1 subun...   130  2e-29
gi|6321427 Proteasome subunit YC7alpha/Y8 (protease yscE subunit...   128  7e-29
pdb|1G65|G Chain G, Crystal Structure Of Epoxomicin:20s Proteaso...   128  7e-29
sp|P12881|PRC2_DROME PROTEASOME 29 KDA SUBUNIT (MULTICATALYTIC E...   126  3e-28
gb|AAB82572.1| (AF025793) 20S proteasome alpha7 subunit [Drosoph...   126  3e-28
pir||T18511 hypothetical protein C0745c - malaria parasite (Plas...   117  1e-25
sp|Q09583|PRC8_CAEEL PUTATIVE PROTEASOME COMPONENT ZK945.2 (MACR...   115  6e-25
gi|11498092 proteasome, subunit beta (psmB) [Archaeoglobus fulgi...   113  2e-24
gb|AAA35020.1| (M31430) scll+ suppressor protein [Saccharomyces ...   101  1e-20
sp|Q58634|PRCB_METJA PROTEASOME BETA SUBUNIT PRECURSOR (MULTICAT...    97  2e-19
gi|6755206 proteasome (prosome, macropain) subunit, beta type 7 ...    96  5e-19
gi|4506203 proteasome (prosome, macropain) subunit, beta type, 7...    92  5e-18
gb|AAF97811.1|AF285103_1 (AF285103) proteasome z subunit [Rattus...    92  5e-18
emb|CAB57537.1| (Y18930) proteasome, beta subunit [Sulfolobus so...    85  1e-15
sp|Q9UXF3|PRCB_SULSO PROTEASOME BETA SUBUNIT PRECURSOR (MULTICAT...    85  1e-15
emb|CAA73621.1| (Y13178) multicatalytic endopeptidase [Arabidops...    83  4e-15
gb|AAC32067.1| (AF043531) 20S proteasome beta subunit PBB2 [Arab...    83  4e-15
gb|AAC32066.1| (AF043530) 20S proteasome beta subunit PBB1 [Arab...    82  5e-15
dbj|BAA19767.1| (D89725) LMP7 [Oryzias latipes]                        78  1e-13

>pir||B75181 multicatalytic endopeptidase complex (EC 3.4.99.46) alpha chain
           PAB0417 - Pyrococcus abyssi (strain Orsay)
           >gi|5458039|emb|CAB49529.1| (AJ248284) proteasome,
           subunit alpha (EC 3.4.99.46) (psmA) [Pyrococcus abyssi]
           Length = 260
           
 Score =  515 bits (1312), Expect = e-145
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 1   MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
           MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL
Sbjct: 1   MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60

Query: 61  IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
           IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD
Sbjct: 61  IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120

Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
           LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK
Sbjct: 121 LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180

Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
           YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE
Sbjct: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240

Query: 241 VEEEEVKEKEEDYSELDSHY 260
           VEEEEVKEKEEDYSELDSHY
Sbjct: 241 VEEEEVKEKEEDYSELDSHY 260


>sp|O59219|PRCA_PYRHO PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           ALPHA SUBUNIT) >gi|7435878|pir||A71033 probable
           proteasome, alpha subunit - Pyrococcus horikoshii
           >gi|3257982|dbj|BAA30665.1| (AP000006) 260aa long
           hypothetical proteasome, alpha subunit [Pyrococcus
           horikoshii]
           Length = 260
           
 Score =  499 bits (1271), Expect = e-140
 Identities = 249/260 (95%), Positives = 258/260 (98%)

Query: 1   MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
           MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKC +GVVLAVEKRITSRL
Sbjct: 1   MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCNEGVVLAVEKRITSRL 60

Query: 61  IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
           IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD
Sbjct: 61  IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120

Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
           LKQMHTQYGGVRPFGAALLMAGVN+KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE+K
Sbjct: 121 LKQMHTQYGGVRPFGAALLMAGVNEKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEEK 180

Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
           Y+DDM+L+EAIKLAIFALAKTMEKPSAENIEVA+ITVKDKKFRKLS+EEIEK+L EVMKE
Sbjct: 181 YKDDMSLEEAIKLAIFALAKTMEKPSAENIEVAIITVKDKKFRKLSREEIEKYLNEVMKE 240

Query: 241 VEEEEVKEKEEDYSELDSHY 260
           VEEEEVKEKEEDYSELDSHY
Sbjct: 241 VEEEEVKEKEEDYSELDSHY 260


>pir||T43887 proteasome alpha chain [imported] - Thermococcus sp
           >gi|2398843|dbj|BAA22211.1| (AB001084) proteasome alpha
           subunit [Thermococcus sp. KS-1]
           Length = 260
           
 Score =  437 bits (1111), Expect = e-122
 Identities = 215/260 (82%), Positives = 242/260 (92%)

Query: 1   MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
           MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVK KDGVVLAVEKRITS+L
Sbjct: 1   MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKWKDGVVLAVEKRITSKL 60

Query: 61  IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
           IEP SYEKIF IDDHIAAA SGIIADARVLV+RARLEAQI+RLTYGEP PL V+VKKICD
Sbjct: 61  IEPSSYEKIFLIDDHIAAAPSGIIADARVLVDRARLEAQIYRLTYGEPVPLTVLVKKICD 120

Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
           LKQ HTQYGGVRPFGAALLMAGVN+KPEL+ETDPSGAYF WKAVAIGSGRNTAMAIFE+ 
Sbjct: 121 LKQAHTQYGGVRPFGAALLMAGVNEKPELFETDPSGAYFEWKAVAIGSGRNTAMAIFEEH 180

Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
           YRDD+  D+AIKLAI ALAKT+E+P+AE IEVA IT+ +K+++KL +EE+EK+L E+++E
Sbjct: 181 YRDDIGKDDAIKLAILALAKTLEEPTAEGIEVAYITMDEKRWKKLPREELEKYLNEILQE 240

Query: 241 VEEEEVKEKEEDYSELDSHY 260
           V+EEEV+EK+EDYSELD +Y
Sbjct: 241 VKEEEVEEKQEDYSELDQNY 260


>sp|Q60177|PRCA_METJA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           ALPHA SUBUNIT) (20S PROTEASOME ALPHA SUBUNIT)
           >gi|2118152|pir||G64373 proteasome alpha subunit homolog
           - Methanococcus jannaschii >gi|1591299|gb|AAB98581.1|
           (U67507) proteasome, subunit alpha (psmA) [Methanococcus
           jannaschii]
           Length = 261
           
 Score =  315 bits (798), Expect = 4e-85
 Identities = 154/251 (61%), Positives = 202/251 (80%), Gaps = 2/251 (0%)

Query: 1   MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
           M  VPP A YDRAITVFSP+GRL+QV YAREAV+RG TA+G+ CKDGVVLAV++RITS+L
Sbjct: 1   MQMVPPSA-YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKL 59

Query: 61  IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
           ++  S EKIFQIDDH+AAA+SG++ADARVL++RARLEAQI+RLTYGE   + ++ KKICD
Sbjct: 60  VKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICD 119

Query: 121 LKQMHTQYGGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFED 179
           +KQ +TQ+GGVRPFG +LL+AG++ ++  L+ETDPSGA   +KA AIGSGR   M + E 
Sbjct: 120 IKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK 179

Query: 180 KYRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMK 239
           +YRDD+TLDE ++LAI AL K  E    EN++V +ITVKD +F+K+  EEI+K + +V K
Sbjct: 180 EYRDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKK 239

Query: 240 EVEEEEVKEKE 250
           ++ EE  KE+E
Sbjct: 240 KLNEENKKEEE 250


>sp|Q59565|PRCA_METTE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           ALPHA SUBUNIT) >gi|11265947|pir||T48878 proteasome psmA,
           alpha chain [validated] - Methanosarcina thermophila
           >gi|1002689|gb|AAA93166.1| (U30483) PsmA [Methanosarcina
           thermophila]
           Length = 247
           
 Score =  300 bits (760), Expect = 1e-80
 Identities = 152/245 (62%), Positives = 193/245 (78%), Gaps = 2/245 (0%)

Query: 6   PQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPES 65
           PQ GYDRAITVFSPDGRLFQV YAREAVKRG TAVG+K  DGVVL V+KRITSRL+E ES
Sbjct: 3   PQMGYDRAITVFSPDGRLFQVEYAREAVKRGTTAVGIKAADGVVLLVDKRITSRLVEAES 62

Query: 66  YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
            EKIFQIDDHI AA+SG++ADAR LV+RAR+EAQ++R++Y E   + VI KKICD KQ +
Sbjct: 63  IEKIFQIDDHIGAATSGLVADARALVDRARVEAQVNRVSYDELIGVEVISKKICDHKQTY 122

Query: 126 TQYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
           TQYGGVRP+G ALL+AGV+DK P L+ETDPSGA   +KA AIG+GRN  + +FE  Y++D
Sbjct: 123 TQYGGVRPYGTALLIAGVDDKRPRLFETDPSGALLEYKATAIGAGRNAVVEVFEADYKED 182

Query: 185 MTLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
           M ++ AI L + AL K  E K  A  +EV V++++DKKFRKL  EE+  ++ +++++ +E
Sbjct: 183 MNIEAAILLGMDALYKAAEGKFDAGTLEVGVVSLQDKKFRKLEPEEVGNYVQQILEKHKE 242

Query: 244 EEVKE 248
            E KE
Sbjct: 243 TENKE 247


>gi|11498101 proteasome, subunit alpha (psmA) [Archaeoglobus fulgidus]
           >gi|6093781|sp|O29760|PRCA_ARCFU PROTEASOME ALPHA
           SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX ALPHA
           SUBUNIT) >gi|7435882|pir||B69311 proteasome, subunit
           alpha (psmA) homolog - Archaeoglobus fulgidus
           >gi|2650136|gb|AAB90747.1| (AE001070) proteasome,
           subunit alpha (psmA) [Archaeoglobus fulgidus]
           Length = 246
           
 Score =  292 bits (740), Expect = 2e-78
 Identities = 137/239 (57%), Positives = 186/239 (77%), Gaps = 1/239 (0%)

Query: 6   PQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPES 65
           PQ GYDRAITVFSPDGRLFQV YAREAVKRGATA+G+KCK+GV+L  +KR+ S+L+E ++
Sbjct: 4   PQMGYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVGSKLLEADT 63

Query: 66  YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
            EKI++ID+HI AA+SG++ADARVL++RAR+EAQI+RLTY EP  +  + KKICD KQ +
Sbjct: 64  IEKIYKIDEHICAATSGLVADARVLIDRARIEAQINRLTYDEPITVKELAKKICDFKQQY 123

Query: 126 TQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           TQYGGVRPFG +LL+AGV++ P+LYETDPSGA   +KA AIG GRN     FE +YRDD+
Sbjct: 124 TQYGGVRPFGVSLLIAGVDEVPKLYETDPSGALLEYKATAIGMGRNAVTEFFEKEYRDDL 183

Query: 186 TLDEAIKLAIFALAKTMEKPSA-ENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
           + D+A+ L + A+  ++E     ENIEV  + V D+ F+++S EE++ ++    + + E
Sbjct: 184 SFDDAMVLGLVAMGLSIESELVPENIEVGYVKVDDRTFKEVSPEELKPYVERANERIRE 242


>sp|O26782|PRCA_METTH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           ALPHA SUBUNIT) >gi|7435881|pir||D69191 proteasome, alpha
           subunit - Methanobacterium thermoautotrophicum (strain
           Delta H) >gi|2621771|gb|AAB85191.1| (AE000848)
           proteasome, alpha subunit [Methanobacterium
           thermoautotrophicum]
           Length = 248
           
 Score =  291 bits (737), Expect = 6e-78
 Identities = 147/242 (60%), Positives = 191/242 (78%), Gaps = 4/242 (1%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           AGYDRAITVFSPDGRLFQV YAREAVKRG T++GVK K+G+VL V+KR TS+L+EP+S E
Sbjct: 7   AGYDRAITVFSPDGRLFQVEYAREAVKRGTTSLGVKSKEGIVLVVDKRPTSKLVEPKSIE 66

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KIFQID+HI AA+SG++ADAR ++ +ARLEAQI+R+TY EP  +  + KKICD+KQM+TQ
Sbjct: 67  KIFQIDEHIGAATSGLVADARAIIEKARLEAQINRITYNEPIRVESLAKKICDMKQMYTQ 126

Query: 128 YGGVRPFGAALLMAGVNDKP-ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           +GGVRPFG AL++ GVN +   L+ETDPSGA   +KA AIG+GR  AM  FE KY DDM 
Sbjct: 127 HGGVRPFGTALIIGGVNGRGCRLFETDPSGALIEYKATAIGAGRPAAMEEFEKKYSDDMN 186

Query: 187 LDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVM--KEVEE 243
           L++AI+LA+ A+ +  E K + E++E+AVI   DKK+R+L  +EI   + E++  KE EE
Sbjct: 187 LNQAIELALDAVYEATEGKTTPESVEIAVIEAADKKYRRLPDDEIRDHVEELLIRKEKEE 246

Query: 244 EE 245
           EE
Sbjct: 247 EE 248


>pir||T48678 proteasome alpha-1 chain [validated] - Haloferax volcanii
           >gi|5833206|gb|AAD53404.1|AF126260_1 (AF126260) alpha-1
           subunit of 20S proteasome [Haloferax volcanii]
           Length = 252
           
 Score =  242 bits (610), Expect = 4e-63
 Identities = 121/246 (49%), Positives = 174/246 (70%), Gaps = 4/246 (1%)

Query: 7   QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           Q  YDR IT+FSPDGRL+QV YAREAVKRG  ++GV+  +GVVLA +KR  S L+EP S 
Sbjct: 7   QQAYDRGITIFSPDGRLYQVEYAREAVKRGTASIGVRTPEGVVLAADKRSRSPLMEPTSV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
           EKI + DDHI  AS+G +ADAR L++ AR ++Q++RL YGEP  +  + K++ D  Q +T
Sbjct: 67  EKIHKADDHIGIASAGHVADARQLIDFARHQSQVNRLRYGEPIGIETLTKEVTDHIQQYT 126

Query: 127 QYGGVRPFGAALLMAGV-NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           Q GG RPFG ALL+ GV N  P LYETDPSG  + WKAV+IG+ R       E+ +RDD+
Sbjct: 127 QVGGARPFGVALLIGGVENGTPRLYETDPSGTPYEWKAVSIGADRGDHQEHLEENFRDDL 186

Query: 186 TLDEAIKLAIFALAKTMEKPSA-ENIEVAVITVKDKKFRKLSKEEIEKFL--GEVMKEVE 242
           TLDE I+LA+ A+A T ++ +A + ++VA ++ + ++F +LS +EIE +L   +++   +
Sbjct: 187 TLDEGIELALEAIASTSDEGTAPDGVDVATVSAETERFVELSNDEIESYLEANDLLATED 246

Query: 243 EEEVKE 248
           +E+ +E
Sbjct: 247 DEQTEE 252


>sp|Q9YC01|PRCA_AERPE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           ALPHA SUBUNIT) >gi|7435889|pir||A72624 probable
           proteasome, alpha subunit APE1449 - Aeropyrum pernix
           (strain K1) >gi|5105133|dbj|BAA80447.1| (AP000061) 258aa
           long hypothetical proteasome , alpha subunit [Aeropyrum
           pernix]
           Length = 258
           
 Score =  231 bits (582), Expect = 8e-60
 Identities = 119/255 (46%), Positives = 174/255 (67%), Gaps = 14/255 (5%)

Query: 1   MAF-VPP-QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITS 58
           MAF +PP Q  YDRA T+FSP+G L+QV YA EAVK+G T++G+K  +GVV+A EKR   
Sbjct: 1   MAFPMPPHQTAYDRAATIFSPEGDLYQVRYAFEAVKKGWTSLGIKTNEGVVIAAEKRFIG 60

Query: 59  RLIEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKI 118
            L++ +  +KI++IDDHI  A +G+  D R+L++ AR+    HRL YGEP P+ ++ K +
Sbjct: 61  PLVDIDDIDKIYKIDDHIGVAFAGMGGDGRILIDYARVFTVRHRLLYGEPPPVELVAKVV 120

Query: 119 CDLKQMHTQYGGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAI 176
            D+KQ +TQ+GGVRPFG AL+ AGVN     ++Y TDP G YF++KA+AIGSG   A  +
Sbjct: 121 ADVKQAYTQHGGVRPFGVALIFAGVNPDGTTKVYRTDPGGQYFSFKAIAIGSGEQVANEM 180

Query: 177 FEDKYRDDMTLDEAIKLAIFAL----AKTMEKPS------AENIEVAVITVKDKKFRKLS 226
           FE  YR DM+L+EA KLA+  L     KT+E          + +E+A ITVK++ F K++
Sbjct: 181 FEKHYRSDMSLEEATKLALKILYAIIRKTVEDKEKAIATLPDQVELAYITVKERMFTKMT 240

Query: 227 KEEIEKFLGEVMKEV 241
           KE++++ +  + +E+
Sbjct: 241 KEQVKEIVDSMREEL 255


>gi|7106389 proteasome (prosome, macropain) subunit, alpha type 7 [Mus
           musculus] >gi|3805978|gb|AAC69150.1| (AF019662) C6-I
           proteasome chain; PSMA7 [Mus musculus]
           Length = 248
           
 Score =  220 bits (554), Expect = 2e-56
 Identities = 120/246 (48%), Positives = 164/246 (65%), Gaps = 6/246 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ KD VVL VEK+  ++L +  +  KI
Sbjct: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +DD++  A +G+ ADAR+++NRAR+E Q HRLT  +P  +  I + I  LKQ +TQ  
Sbjct: 63  CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
           G RPFG + L+ G   +  P LY+TDPSG Y AWKA AIG G  +     E  Y DD   
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
           T D  IKL I AL + ++    +NIE+AV+  +D+  + L+ EEIEK++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILNPEEIEKYVAEIEKEKEENE 240

Query: 246 VKEKEE 251
            K++++
Sbjct: 241 KKKQKK 246


>gb|AAK41034.1| Proteasome subunit [Sulfolobus solfataricus]
           Length = 241
           
 Score =  219 bits (552), Expect = 3e-56
 Identities = 110/238 (46%), Positives = 160/238 (67%), Gaps = 4/238 (1%)

Query: 1   MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
           MAF P   GYDRAIT+FSPDG L+QV+YA EAVK+G TA+G+K K  VV+A EKR    L
Sbjct: 1   MAFGPAAMGYDRAITIFSPDGSLYQVDYAFEAVKKGWTAIGIKSKSSVVIASEKRKAQSL 60

Query: 61  IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
           ++ +S EK+F IDDH+  + +G+ +D RVL++ AR  A  HRL Y EP  +  + K + D
Sbjct: 61  LDVDSIEKVFLIDDHVGCSFAGLASDGRVLIDYARNIALQHRLIYDEPVSIDYLTKSVAD 120

Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFED 179
           +KQM+TQ+GGVRPFG AL++AG++   P+L+ T+PSG Y  ++AVAIG G  TA    E 
Sbjct: 121 VKQMYTQHGGVRPFGVALVIAGIDKSVPKLFMTEPSGQYMPYQAVAIGQGYYTATEFLEK 180

Query: 180 KYRDDMTLDEAIKLAIFALAKTM---EKPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
            Y++D+ ++E I LA+ AL+ T+   EK +   +E+   + +   F K++ E+   +L
Sbjct: 181 NYKEDLNVEETILLALKALSATLKPNEKLTPNTVEIGYASTQTGLFLKMTNEDKNMYL 238


>emb|CAB57565.1| (Y18930) proteasome alpha subunit (N-terminus) [Sulfolobus
           solfataricus]
           Length = 241
           
 Score =  219 bits (552), Expect = 3e-56
 Identities = 110/238 (46%), Positives = 160/238 (67%), Gaps = 4/238 (1%)

Query: 1   MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
           MAF P   GYDRAIT+FSPDG L+QV+YA EAVK+G TA+G+K K  VV+A EKR    L
Sbjct: 1   MAFGPAAMGYDRAITIFSPDGSLYQVDYAFEAVKKGWTAIGIKSKSSVVIASEKRKAQSL 60

Query: 61  IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
           ++ +S EK+F IDDH+  + +G+ +D RVL++ AR  A  HRL Y EP  +  + K + D
Sbjct: 61  LDVDSIEKVFLIDDHVGCSFAGLASDGRVLIDYARNIALQHRLIYDEPVSIDYLTKSVAD 120

Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFED 179
           +KQM+TQ+GGVRPFG AL++AG++   P+L+ T+PSG Y  ++AVAIG G  TA    E 
Sbjct: 121 VKQMYTQHGGVRPFGVALVIAGIDKSVPKLFMTEPSGQYMPYQAVAIGQGYYTATEFLEK 180

Query: 180 KYRDDMTLDEAIKLAIFALAKTM---EKPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
            Y++D+ ++E I LA+ AL+ T+   EK +   +E+   + +   F K++ E+   +L
Sbjct: 181 NYKEDLNVEETILLALKALSATLKPNEKLTPNTVEIGYASTQTGLFLKMTNEDKNMYL 238


>sp|P48004|PRC6_RAT PROTEASOME SUBUNIT RC6-1 (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           SUBUNIT RC6-1) >gi|2118151|pir||S60038 multicatalytic
           endopeptidase complex (EC 3.4.99.46) alpha chain RC6-I -
           rat >gi|1089797|dbj|BAA06463.1| (D30804) proteasome
           subunit RC6-1 [Rattus rattus]
           Length = 254
           
 Score =  218 bits (550), Expect = 5e-56
 Identities = 122/252 (48%), Positives = 166/252 (65%), Gaps = 12/252 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ +D VVL VEK+  ++L +  +  KI
Sbjct: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62

Query: 70  FQIDDH------IAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQ 123
             +DD+      + A+ SG+ ADAR+++NRAR+E Q HRLT G+P  +  I + I  LKQ
Sbjct: 63  CALDDNVCMAFAVVASVSGLTADARIVINRARVECQSHRLTVGDPVTVEYITRYIASLKQ 122

Query: 124 MHTQYGGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
            +TQ  G RPFG + L+ G   +  P LY+TDPSG Y AWKA AIG G  +     E  Y
Sbjct: 123 RYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY 182

Query: 182 RDDM--TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMK 239
            DD   T D  IKL I AL + ++    +NIE+AV+  +D+  + LS EEIEK++ E+ K
Sbjct: 183 TDDAIETDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILSPEEIEKYVAEIEK 240

Query: 240 EVEEEEVKEKEE 251
           E EE E K++++
Sbjct: 241 EKEENEKKKQKK 252


>dbj|BAA89276.1| (AB027707) alpha 4 subunit of 20S proteasome [Carassius auratus]
           Length = 251
           
 Score =  218 bits (549), Expect = 6e-56
 Identities = 120/251 (47%), Positives = 164/251 (64%), Gaps = 6/251 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           A YDRAITVFSPDG LFQV YA+EAVK+G+TAVG++ KD VVL VEK+  ++L E  +  
Sbjct: 3   ARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGKDIVVLGVEKKSVAKLQEERTVR 62

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI  +D+H+  A +G+ ADAR+++NRAR+E Q HRLT  +P  +  I + I  LKQ +TQ
Sbjct: 63  KICALDEHVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIATLKQRYTQ 122

Query: 128 YGGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
             G RPFG + L+ G   +  P LY+TDPSG Y AWKA AIG    T     E  Y D+ 
Sbjct: 123 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTDEA 182

Query: 186 TL--DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
               ++AIKLAI AL + ++    +NIE+AVI  +++  + L  +EIE  + E+ KE EE
Sbjct: 183 IASDNDAIKLAIKALLEVVQS-GGKNIELAVIR-RNQPLKILESKEIETLVAEIEKEKEE 240

Query: 244 EEVKEKEEDYS 254
           E  K+K++  S
Sbjct: 241 EAEKKKQKKSS 251


>sp|P25156|PRCA_THEAC PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           ALPHA SUBUNIT) >gi|1076173|pir||S55350 multicatalytic
           endopeptidase complex (EC 3.4.99.46) alpha chain -
           Thermoplasma acidophilum >gi|1633359|pdb|1PMA|A Chain A,
           Proteasome From Thermoplasma Acidophilum
           >gi|1633361|pdb|1PMA|C Chain C, Proteasome From
           Thermoplasma Acidophilum >gi|1633362|pdb|1PMA|D Chain D,
           Proteasome From Thermoplasma Acidophilum
           >gi|1633363|pdb|1PMA|E Chain E, Proteasome From
           Thermoplasma Acidophilum >gi|1633364|pdb|1PMA|F Chain F,
           Proteasome From Thermoplasma Acidophilum
           >gi|1633365|pdb|1PMA|G Chain G, Proteasome From
           Thermoplasma Acidophilum >gi|1633366|pdb|1PMA|H Chain H,
           Proteasome From Thermoplasma Acidophilum
           >gi|1633367|pdb|1PMA|I Chain I, Proteasome From
           Thermoplasma Acidophilum >gi|1633368|pdb|1PMA|J Chain J,
           Proteasome From Thermoplasma Acidophilum
           >gi|1633369|pdb|1PMA|K Chain K, Proteasome From
           Thermoplasma Acidophilum >gi|1633370|pdb|1PMA|L Chain L,
           Proteasome From Thermoplasma Acidophilum
           >gi|1633371|pdb|1PMA|M Chain M, Proteasome From
           Thermoplasma Acidophilum >gi|1633372|pdb|1PMA|N Chain N,
           Proteasome From Thermoplasma Acidophilum
           >gi|1633373|pdb|1PMA|O Chain O, Proteasome From
           Thermoplasma Acidophilum >gi|395159|emb|CAA42094.1|
           (X59507) alpha-subunit of the proteasome [Thermoplasma
           acidophilum] >gi|10640633|emb|CAC12411.1| (AL445067)
           proteasome alpha subunit [Thermoplasma acidophilum]
           Length = 233
           
 Score =  218 bits (549), Expect = 6e-56
 Identities = 113/230 (49%), Positives = 164/230 (71%), Gaps = 3/230 (1%)

Query: 7   QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           Q  YDRAITVFSPDGRLFQV YAREAVK+G+TA+G+K  +GV+L  +K++ SRLIE  S 
Sbjct: 5   QMAYDRAITVFSPDGRLFQVEYAREAVKKGSTALGMKFANGVLLISDKKVRSRLIEQNSI 64

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
           EKI  IDD++AA +SG++ADARVLV+ AR+ AQ  ++TYG    +  +VK++ D  Q +T
Sbjct: 65  EKIQLIDDYVAAVTSGLVADARVLVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYT 124

Query: 127 QYGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           QYGGVRP+G +L+ AG++   P L++ DP+G    +KA AIGSG++  ++  E +Y++++
Sbjct: 125 QYGGVRPYGVSLIFAGIDQIGPRLFDCDPAGTINEYKATAIGSGKDAVVSFLEREYKENL 184

Query: 186 TLDEAIKLAIFALAKTMEK-PSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
              EA+ L I AL  ++E+    +  E+A ITV   K+R   +EE++KFL
Sbjct: 185 PEKEAVTLGIKALKSSLEEGEELKAPEIASITV-GNKYRIYDQEEVKKFL 233


>gi|4506189 proteasome (prosome, macropain) subunit, alpha type, 7 [Homo
           sapiens] >gi|11421089|ref|XP_009560.1| proteasome
           (prosome, macropain) subunit, alpha type, 7 [Homo
           sapiens] >gi|2555136|gb|AAB81515.1| (AF022815)
           proteasome subunit XAPC7 [Homo sapiens]
           Length = 248
           
 Score =  217 bits (548), Expect = 8e-56
 Identities = 118/246 (47%), Positives = 164/246 (65%), Gaps = 6/246 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ +D VVL VEK+  ++L +  +  KI
Sbjct: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +DD++  A +G+ ADAR+++NRAR+E Q HRLT  +P  +  I + I  LKQ +TQ  
Sbjct: 63  CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
           G RPFG + L+ G   +  P LY+TDPSG Y AWKA AIG G  +     E  Y D+   
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
           T D  IKL I AL + ++    +NIE+AV+  +D+  + L+ EEIEK++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQSLKILNPEEIEKYVAEIEKEKEENE 240

Query: 246 VKEKEE 251
            K++++
Sbjct: 241 KKKQKK 246


>gb|AAG18783.1| (AE004983) proteasome, subunit beta; PsmB [Halobacterium sp. NRC-1]
           Length = 253
           
 Score =  217 bits (547), Expect = 1e-55
 Identities = 110/247 (44%), Positives = 160/247 (64%), Gaps = 2/247 (0%)

Query: 7   QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           Q  YDR IT+FSPDGRL+QV YAREAVKRG  ++GV+  +GVVL V+K+  S L+E  S 
Sbjct: 7   QQAYDRGITIFSPDGRLYQVEYAREAVKRGTASIGVRTPEGVVLVVDKQTRSPLLEGSSV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
           EK+ +IDDH+ AAS+G +ADAR LV+ AR ++Q+ R+ Y EP  +  + K + D  Q +T
Sbjct: 67  EKLHKIDDHVGAASAGHVADARQLVDFARQQSQVERVRYDEPIGVRTLTKSVTDHIQQYT 126

Query: 127 QYGGVRPFGAALLMAGV-NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           Q GG RPFG ALL+AGV   +P L+ETDPSG    WKAVAIGS R       ED+Y   +
Sbjct: 127 QVGGARPFGVALLIAGVEGGEPRLFETDPSGTSNEWKAVAIGSNRGDIQEFLEDEYDAGL 186

Query: 186 TLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
           ++D+ I LA+ AL +  E   S + + V ++      +R+L+ +E + ++ ++    ++ 
Sbjct: 187 SVDDGIDLALRALNEGREDALSGDGVGVGIVDADTGTYRELAADESQSYIDDIEDAADDS 246

Query: 245 EVKEKEE 251
           +  + EE
Sbjct: 247 DDDDDEE 253


>gb|AAC99402.1| (AF054185) proteasome subunit HSPC [Homo sapiens]
           Length = 248
           
 Score =  216 bits (545), Expect = 2e-55
 Identities = 117/246 (47%), Positives = 164/246 (66%), Gaps = 6/246 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ +D VVL VEK+  ++L +  +  KI
Sbjct: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +DD++  A +G+ ADAR+++NRAR+E Q HRLT  +P  +  I + I  LKQ +TQ  
Sbjct: 63  CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
           G RPFG + L+ G   +  P LY+TDPSG Y AWKA +IG G  +     E  Y D+   
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANSIGRGAKSVREFLEKNYTDEAIE 182

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
           T D  IKL I AL + ++    +NIE+AV+  +D+  + L+ EEIEK++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQSLKILNPEEIEKYVAEIEKEKEENE 240

Query: 246 VKEKEE 251
            K++++
Sbjct: 241 KKKQKK 246


>sp|O04861|PRC6_ORYSA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           ALPHA SUBUNIT) >gi|7435885|pir||T04300 probable
           multicatalytic endopeptidase complex (EC 3.4.99.46)
           alpha chain - rice >gi|1930070|gb|AAB51521.1| (U92540)
           proteasome alpha subunit [Oryza sativa]
           Length = 249
           
 Score =  214 bits (539), Expect = 9e-55
 Identities = 121/245 (49%), Positives = 159/245 (64%), Gaps = 6/245 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           A YDRAITVFSPDG LFQV YA EAV++G  AVGV+  D VVL VEK+ T +L +  S  
Sbjct: 2   ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTVVLGVEKKSTPKLQDSRSMR 61

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI  +D HIA A +G+ ADARVL+NRAR+E Q HRLT  +P  +  I + I  L+Q +TQ
Sbjct: 62  KIASLDTHIALACAGLKADARVLINRARVECQSHRLTVEDPVTVEYITRYIAGLQQKYTQ 121

Query: 128 YGGVRPFGAALLMAGVN---DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
            GGVRPFG + L+ G +   +KP LY+TDPSG + AWKA A G   N+     E  Y+ D
Sbjct: 122 SGGVRPFGLSTLIVGFDPYTEKPALYQTDPSGTFSAWKANATGRNSNSMREFLEKNYK-D 180

Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
            +  E IKLAI AL + +E    +NIE+AV+T KD   R+L + EI++++ E+  E    
Sbjct: 181 TSGKETIKLAIRALLEVVES-GGKNIEIAVMTHKD-GLRELEEAEIDEYVAEIEAEKAAA 238

Query: 245 EVKEK 249
           E  +K
Sbjct: 239 EAAKK 243


>dbj|BAA86962.1| (AB004782) 20S proteasome alpha 4 subunit [Xenopus laevis]
           Length = 248
           
 Score =  213 bits (536), Expect = 2e-54
 Identities = 116/246 (47%), Positives = 164/246 (66%), Gaps = 6/246 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ K+ VVL VEK+  ++L +  +  KI
Sbjct: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKEIVVLGVEKKSVAKLQDERTVRKI 62

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +D+++  A +G+ ADAR+++NRAR+E Q HRLT  +P  +  I + I  LKQ +TQ  
Sbjct: 63  CALDENVFMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
           G RPFG + L+ G   +  P LY+TDPSG Y AWKA AIG G  +     E  Y D+   
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKHYTDEAIE 182

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
           T D  IKL I AL + ++    +NIE+AV+  +D+  + L+ EEIE+++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILNPEEIERYVAEIEKEKEENE 240

Query: 246 VKEKEE 251
            K++++
Sbjct: 241 KKKQKK 246


>dbj|BAA86956.1| (AB027463) 20S proteasome alpha 4 subunit [Xenopus laevis]
           Length = 247
           
 Score =  213 bits (536), Expect = 2e-54
 Identities = 116/246 (47%), Positives = 164/246 (66%), Gaps = 6/246 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ K+ VVL VEK+  ++L +  +  KI
Sbjct: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKEIVVLGVEKKSVAKLQDERTVRKI 62

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +D+++  A +G+ ADAR+++NRAR+E Q HRLT  +P  +  I + I  LKQ +TQ  
Sbjct: 63  CALDENVFMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
           G RPFG + L+ G   +  P LY+TDPSG Y AWKA AIG G  +     E  Y D+   
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKHYTDEAIE 182

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
           T D  IKL I AL + ++    +NIE+AV+  +D+  + L+ EEIE+++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILNPEEIERYVAEIEKEKEENE 240

Query: 246 VKEKEE 251
            K++++
Sbjct: 241 KKKQKK 246


>pir||JC5510 multicatalytic endopeptidase complex (EC 3.4.99.46) alpha chain -
           chicken >gi|485265|gb|AAC60206.1| (U09226) proteasome 28
           kDa subunit homolog, similar to Swiss-Prot Accession
           Number P22769 [Gallus gallus]
           Length = 249
           
 Score =  212 bits (535), Expect = 3e-54
 Identities = 120/247 (48%), Positives = 164/247 (65%), Gaps = 7/247 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ KD VVL VEK+  ++L +  +  KI
Sbjct: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +DD++  A +G+ ADAR+++NRAR+E Q HRLT  +P  +  I + I  LKQ +TQ  
Sbjct: 63  CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSK 122

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
             RPFG + L+ G   +  P LY+TDPSG Y AWKA AIG G  +    FE  Y D+   
Sbjct: 123 RRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVRVEFEKNYTDEAIE 182

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKL-SKEEIEKFLGEVMKEVEEE 244
           T D  IKL I AL + ++    +NIE+AV+  +D+  + L S EEIEK++ E+ KE EE 
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILTSPEEIEKYVAEIEKEKEEN 240

Query: 245 EVKEKEE 251
           E K++++
Sbjct: 241 EKKKQKK 247


>dbj|BAA76428.1| (AB025000) multicatalytic endopeptidase complex [Cicer arietinum]
           Length = 249
           
 Score =  211 bits (531), Expect = 8e-54
 Identities = 118/245 (48%), Positives = 157/245 (63%), Gaps = 6/245 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           A YDRAITVFSPDG LFQV YA EAV++G  AVGV+  D VVL VEK+ T++L +  S  
Sbjct: 2   ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDNVVLGVEKKSTAKLQDTRSVR 61

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI  +DDHIA A +G+ ADARVL+NRAR+E Q HRLT  +P  +  I + I  L+Q +TQ
Sbjct: 62  KIVNLDDHIALACAGLKADARVLINRARVECQSHRLTVEDPVTVEYITRYIAGLQQKYTQ 121

Query: 128 YGGVRPFGAALLMAGVN---DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
            GGVRPFG + L+ G +     P LY+TDPSG + AWKA A G   N+     E  ++ +
Sbjct: 122 SGGVRPFGLSTLIVGFDPYTGSPSLYQTDPSGTFSAWKANATGRNSNSIREFLEKNFK-E 180

Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
            +  E +KLAI AL + +E    +NIEVAV+T K+   R+L + EI+  + E+  E    
Sbjct: 181 TSGQETVKLAIRALLEVVES-GGKNIEVAVMT-KENGLRQLEEAEIDAIVAEIEAEKAAA 238

Query: 245 EVKEK 249
           E  +K
Sbjct: 239 EAAKK 243


>sp|P30186|PRC6_ARATH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           ALPHA SUBUNIT) (TAS-G64) >gi|478764|pir||S29240
           multicatalytic endopeptidase complex (EC 3.4.99.46)
           alpha chain - Arabidopsis thaliana
           >gi|16445|emb|CAA47298.1| (X66825) proteosome alpha
           subunit [Arabidopsis thaliana]
           >gi|3421080|gb|AAC32058.1| (AF043522) 20S proteasome
           subunit PAD1 [Arabidopsis thaliana]
           >gi|6562278|emb|CAB62648.1| (AL132980) multicatalytic
           endopeptidase complex [Arabidopsis thaliana]
           >gi|742351|prf||2009376B proteasome:SUBUNIT=alpha
           [Arabidopsis thaliana]
           Length = 250
           
 Score =  210 bits (529), Expect = 1e-53
 Identities = 117/245 (47%), Positives = 157/245 (63%), Gaps = 5/245 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           A YDRAITVFSPDG LFQV YA EAV++G  AVGV+  D VVLAVEK+ T +L +  S  
Sbjct: 2   ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTVVLAVEKKSTPKLQDSRSAR 61

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI  +D+HIA A +G+ ADARVL+N+AR+E Q HRLT  +P  +  I + I  L+Q +TQ
Sbjct: 62  KIVSLDNHIALACAGLKADARVLINKARIECQSHRLTLEDPVTVEYITRYIAGLQQKYTQ 121

Query: 128 YGGVRPFGAALLMAGVNDK---PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
            GGVRPFG + L+ G +     P LY+TDPSG + AWKA A G   N+     E  Y++ 
Sbjct: 122 SGGVRPFGLSTLIVGFDPYTRIPALYQTDPSGTFSAWKANATGRNSNSIREFLEKNYKES 181

Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
               E +KLAI AL + +E    +NIEVAV+T ++   ++L +EEI+  + E+  E    
Sbjct: 182 AG-QETVKLAIRALLEVVES-GGKNIEVAVMTREEGVLKQLEEEEIDIIVAEIEAEKAAA 239

Query: 245 EVKEK 249
           E  +K
Sbjct: 240 EAAKK 244


>gb|AAC32059.1| (AF043523) 20S proteasome subunit PAD2 [Arabidopsis thaliana]
           >gi|10177129|dbj|BAB10419.1| (AB011474) 20S proteasome
           subunit PAD2 [Arabidopsis thaliana]
           Length = 250
           
 Score =  209 bits (527), Expect = 2e-53
 Identities = 117/245 (47%), Positives = 157/245 (63%), Gaps = 5/245 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           A YDRAITVFSPDG LFQV YA EAV++G  AVGV+  D VVLAVEK+ T +L +  S  
Sbjct: 2   ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTVVLAVEKKSTPKLQDSRSAR 61

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI  +D+HIA A +G+ ADARVL+N+AR+E Q HRLT  +P  +  I + I  L+Q +TQ
Sbjct: 62  KIVSLDNHIALACAGLKADARVLINKARIECQSHRLTLEDPVTVEYITRYIAGLQQKYTQ 121

Query: 128 YGGVRPFGAALLMAGVND---KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
            GGVRPFG + L+ G +     P LY+TDPSG + AWKA A G   N+     E  Y++ 
Sbjct: 122 SGGVRPFGLSTLIVGFDPYSRLPSLYQTDPSGTFSAWKANATGRNSNSIREFLEKNYKES 181

Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
            +  E IKLAI AL + +E    +NIEVAV+T ++   R+L + EI+  + ++  E    
Sbjct: 182 -SGQETIKLAIRALLEVVES-GGKNIEVAVMTREETGLRQLEEAEIDAIVAKIEAEKAAA 239

Query: 245 EVKEK 249
           E  +K
Sbjct: 240 EAAKK 244


>sp|O24030|PRC6_LYCES PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           ALPHA SUBUNIT) >gi|7435877|pir||T07744 multicatalytic
           endopeptidase complex (EC 3.4.99.46) alpha chain -
           tomato >gi|2315211|emb|CAA74725.1| (Y14339) proteasome
           alpha subunit [Lycopersicon esculentum]
           Length = 259
           
 Score =  208 bits (523), Expect = 7e-53
 Identities = 117/245 (47%), Positives = 156/245 (62%), Gaps = 6/245 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           A YDRAITVFSPDG LFQV YA EAV++G  AVGV+  D VVL VEK+ T +L +  S  
Sbjct: 2   ARYDRAITVFSPDGHLFQVEYAMEAVRKGNAAVGVRGTDTVVLGVEKKSTPKLQDSRSVR 61

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI  +DDHIA A +G+ ADARVLVN+AR+E Q HRLT  +P  +  I + I  L+Q +TQ
Sbjct: 62  KIVNLDDHIALACAGLKADARVLVNKARIECQSHRLTVEDPVTVEYITRYIAGLQQKYTQ 121

Query: 128 YGGVRPFGAALLMAGVNDK---PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
            GGVRPFG + L+ G +     P LY+TDPSG + AWKA A G   N+     E  Y+ +
Sbjct: 122 SGGVRPFGLSTLIIGFDPHTGVPSLYQTDPSGTFSAWKANATGRNSNSTREFLEKNYK-E 180

Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
            +  E +KLAI AL + +E    +NIEVAV+T K+   ++L + EI+  + E+  E    
Sbjct: 181 TSGQETVKLAIRALLEVVES-GGKNIEVAVMT-KEHGLKQLEEAEIDAIVAEIEAEKAAA 238

Query: 245 EVKEK 249
           E  ++
Sbjct: 239 EAAKR 243


>emb|CAA73622.1| (Y13179) multicatalytic endopeptidase [Arabidopsis thaliana]
           >gi|2511582|emb|CAA73623.1| (Y13180) multicatalytic
           endopeptidase [Arabidopsis thaliana]
           Length = 235
           
 Score =  207 bits (522), Expect = 9e-53
 Identities = 115/236 (48%), Positives = 154/236 (64%), Gaps = 5/236 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           A YDRAITVFSPDG LFQV YA EAV++G  AVGV+  D VVLAVEK+ T +L +  S  
Sbjct: 2   ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTVVLAVEKKSTPKLQDSRSAR 61

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI  +D+HIA A +G+ ADARVL+N+AR+E Q HRLT  +P  +  I + I  L+Q +TQ
Sbjct: 62  KIVSLDNHIALACAGLKADARVLINKARIECQSHRLTLEDPVTVEYITRYIAGLQQKYTQ 121

Query: 128 YGGVRPFGAALLMAGVND---KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
            GGVRPFG + L+ G +     P LY+TDPSG + AWKA A G   N+     E  Y++ 
Sbjct: 122 SGGVRPFGLSTLIVGFDPYSRLPSLYQTDPSGTFSAWKANATGRNSNSIREFLEKNYKES 181

Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
            +  E IKLAI AL + +E    +NIEVAV+T ++   R+L + EI+  + ++  E
Sbjct: 182 -SGQETIKLAIRALLEVVES-GGKNIEVAVMTREETGLRQLEEAEIDAIVAKIEAE 235


>sp|P52427|PRC9_SPIOL PROTEASOME 27 KD SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 27
           KD SUBUNIT) >gi|7435866|pir||T09160 proteasome subunit -
           spinach >gi|1262146|emb|CAA65660.1| (X96974) proteasome
           subunit [Spinacia oleracea]
           Length = 250
           
 Score =  206 bits (519), Expect = 2e-52
 Identities = 104/235 (44%), Positives = 160/235 (67%), Gaps = 8/235 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA EA+    +A+G+  KDGVVL  EK++TS+L++   S EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILAKDGVVLIGEKKVTSKLLQTSTSTEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +++IDDH+A A +GI++DA +L+N AR++AQ +  +Y EP P+  +V+ +CD KQ +TQ+
Sbjct: 65  MYKIDDHVACAVAGIMSDANILINTARVQAQRYTFSYQEPMPVEQLVQSLCDTKQGYTQF 124

Query: 129 GGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+RPFG + L AG   N   +LY +DPSG Y  WKA AIG+    A ++ +  Y+DD+T
Sbjct: 125 GGLRPFGVSFLFAGWDKNYGFQLYMSDPSGNYGGWKATAIGANNQAAQSMLKQDYKDDVT 184

Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITVKDK---KFRKLSKEEIEKFLGE 236
            ++A+KLA+ AL+KTM+  S  +E +E+A + +      K++  S E + + L E
Sbjct: 185 REDAVKLALKALSKTMDSTSLTSEKLELAEVYLLPSGKVKYQVHSPESLNRLLTE 239


>dbj|BAA99540.1| (AB032061) alpha 4 subunit of 20S proteasome [Oryza sativa]
           Length = 248
           
 Score =  206 bits (518), Expect = 3e-52
 Identities = 120/245 (48%), Positives = 157/245 (63%), Gaps = 7/245 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           A YDRAITVFSPDG LFQV YA EAV++G  AVGV+  D VVL VEK+ T +L +  S  
Sbjct: 2   ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGSDTVVLGVEKKSTPKLQDSRSVR 61

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI  +D HIA A +G+ ADARVL NRAR+E Q HRLT  +   +  I + I  L+Q +TQ
Sbjct: 62  KIASLDTHIALACAGLKADARVL-NRARVECQSHRLTVEDAVTVEYITRYIAGLQQKYTQ 120

Query: 128 YGGVRPFGAALLMAGVN---DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
            GGVRPFG + L+ G +   DKP LY+TDPSG + AWKA A G   N+     E  Y+ +
Sbjct: 121 SGGVRPFGLSTLIVGFDPYTDKPALYQTDPSGTFSAWKANATGRNSNSMREFLEKNYK-E 179

Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
            +  E IKLAI AL + +E    +NIE+AV+T KD   R+L + EI++++ E+  E    
Sbjct: 180 TSGKETIKLAIRALLEVVES-GGKNIEIAVMTQKD-GLRQLEEAEIDEYVAEIEAEKAAA 237

Query: 245 EVKEK 249
           E  +K
Sbjct: 238 EAAKK 242


>emb|CAA67761.1| (X99382) alpha proteasome [Entamoeba histolytica]
           Length = 247
           
 Score =  205 bits (517), Expect = 3e-52
 Identities = 113/238 (47%), Positives = 155/238 (64%), Gaps = 7/238 (2%)

Query: 11  DRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIF 70
           D  +  FS +GRLFQV YA EA+K G+T +G++ K+GVVLAVEKRI+S L+   S EKI 
Sbjct: 9   DHGVNTFSSEGRLFQVEYATEAMKLGSTVIGIQTKEGVVLAVEKRISSPLMLGSSIEKII 68

Query: 71  QIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGG 130
           +IDDHI AA SG+ ADAR L++ ARLEAQ HR  Y EP  + V+ + I DL     +   
Sbjct: 69  EIDDHIGAAVSGLTADARTLIDNARLEAQNHRFMYDEPINVEVVAQAISDLSLRFGEGSR 128

Query: 131 -----VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
                 RPFG ALL+AGV++  P L++TDPSG +  + A A G+G   A +I  +KY   
Sbjct: 129 KKKVMSRPFGVALLIAGVDETGPRLFQTDPSGMFIEFYAKATGAGTEAAQSILHEKYNKS 188

Query: 185 MTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEV 241
           MTL EA  LA+  L + M EK +++N+EVA++TV+ KKF  +    IE  +GE+ +E+
Sbjct: 189 MTLREAEILALSTLKQVMEEKLNSKNVEVALVTVEKKKFEIMDTAFIENLIGEIKEEL 246


>emb|CAB86711.1| (AL163505) 20S proteasome alpha 5 subunit [Leishmania major]
           Length = 244
           
 Score =  205 bits (517), Expect = 3e-52
 Identities = 107/235 (45%), Positives = 150/235 (63%), Gaps = 7/235 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GR+FQ+ YA EA+K G+T++G++   GVVLA EKR+ S L+ P S  KI
Sbjct: 8   YDRGVNTFSPEGRIFQIEYAVEAIKLGSTSLGIRTPKGVVLAAEKRVPSTLVVPSSMSKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HIAA  SG++ADAR+LV  AR+E+Q HR TY EP  +       CDL     + G
Sbjct: 68  MEIDSHIAAVMSGMVADARILVEHARVESQNHRFTYNEPMSVESCTLATCDLSIQFGESG 127

Query: 130 G-----VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD 183
           G      RPFG +LL+AGV++K P+L++TDPSG +  + A AIG G   A ++F ++Y  
Sbjct: 128 GKRKLMSRPFGVSLLIAGVDEKGPQLWQTDPSGTHTRYDAQAIGGGAEAAQSVFTERYHR 187

Query: 184 DMTLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           +MTL+E   LA+  L + ME + S ENIEVAV+   D K    +  EI+  +  +
Sbjct: 188 NMTLEEGETLAVDILKQVMEDQLSPENIEVAVVRADDGKLHMYTPTEIKAIMSRM 242


>gb|AAC32057.1| (AF043521) 20S proteasome subunit PAC1 [Arabidopsis thaliana]
           >gi|9229453|dbj|BAA99919.1| (AP001306) 20S proteasome
           subunit PAC1 (gb|AAC32057.1) [Arabidopsis thaliana]
           Length = 250
           
 Score =  203 bits (512), Expect = 1e-51
 Identities = 103/233 (44%), Positives = 155/233 (66%), Gaps = 8/233 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA EA+    +A+G+  KDGVVL  EK++TS+L++   S EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +++IDDH+A A +GI++DA +L+N AR++AQ +   Y EP P+  +V+ +CD KQ +TQ+
Sbjct: 65  MYKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQF 124

Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+RPFG + L AG +     +LY +DPSG Y  WKA A+G+    A +I +  Y+DD T
Sbjct: 125 GGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYKDDAT 184

Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITV---KDKKFRKLSKEEIEKFL 234
            +EA++LA+  L KTM+  S  +E +E+A + +   K  K+   S E + K L
Sbjct: 185 REEAVELALKVLTKTMDSTSLTSEKLELAEVYLTPSKTVKYHVHSPESLTKLL 237


>gb|AAC35982.1| (AF088914) proteasome alpha subunit [Petunia x hybrida]
           Length = 249
           
 Score =  203 bits (512), Expect = 1e-51
 Identities = 101/232 (43%), Positives = 158/232 (67%), Gaps = 7/232 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA EA+    +A+G+  KDGVVL  EK++TS+L++   S EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGISSKDGVVLVGEKKVTSKLLQTSTSSEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +++IDDH+A A +GI++DA +L+N AR++AQ +  +Y EP P+  +V+ +CD KQ +TQY
Sbjct: 65  MYKIDDHVACAVAGIMSDANILINTARVQAQRYTFSYQEPMPVEQLVQSLCDTKQGYTQY 124

Query: 129 GGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+ PFG + L AG   N   +L+ +DPSG Y  WKA AIG+    A ++ +  Y+DD+T
Sbjct: 125 GGLPPFGVSFLFAGWDKNFGFQLFMSDPSGNYAGWKAAAIGANNQAAQSMLKQDYKDDIT 184

Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITVKD--KKFRKLSKEEIEKFL 234
            +EA++LA+  L+KTM+  S  +E +E+A + + +   K++  S E++   L
Sbjct: 185 REEAVQLALKVLSKTMDSTSLTSEKLELAEVFLSNGKVKYQACSPEKLNSML 236


>emb|CAA73624.1| (Y13181) multicatalytic endopeptidase [Arabidopsis thaliana]
           Length = 250
           
 Score =  202 bits (508), Expect = 4e-51
 Identities = 102/233 (43%), Positives = 154/233 (65%), Gaps = 8/233 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV Y  EA+    +A+G+  KDGVVL  EK++TS+L++   S EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYVMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +++IDDH+A A +GI++DA +L+N AR++AQ +   Y EP P+  +V+ +CD KQ +TQ+
Sbjct: 65  MYKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQF 124

Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+RPFG + L AG +     +LY +DPSG Y  WKA A+G+    A +I +  Y+DD T
Sbjct: 125 GGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYKDDAT 184

Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITV---KDKKFRKLSKEEIEKFL 234
            +EA++LA+  L KTM+  S  +E +E+A + +   K  K+   S E + K L
Sbjct: 185 REEAVELALKVLTKTMDSTSLTSEKLELAEVYLTPSKTVKYHVHSPESLTKLL 237


>sp|P34120|PRC6_DICDI PROTEASOME SUBUNIT DD5 (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           SUBUNIT DD5) >gi|347511|gb|AAA33234.1| (L22213)
           proteasome [Dictyostelium discoideum]
           Length = 250
           
 Score =  201 bits (507), Expect = 5e-51
 Identities = 113/246 (45%), Positives = 161/246 (64%), Gaps = 5/246 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           A YDRAITVFSPDG LFQV YA EAV++G  AVGV+ KD +VL VEK+ T++L +  S  
Sbjct: 4   ARYDRAITVFSPDGHLFQVEYAMEAVRKGTVAVGVRGKDVIVLGVEKKATAKLQDARSIR 63

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI ++DDHI    +G+ AD+RVL+++A +E Q +RLT  +   +  I K I  ++Q +TQ
Sbjct: 64  KIVKLDDHICLTFAGLTADSRVLISKALMECQSYRLTVEDSPSVEYISKFIAGIQQRYTQ 123

Query: 128 YGGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
            GGVRPFG + L+ G   +  P LY+TDPSG+Y +WKA AIG    +     E  Y  D+
Sbjct: 124 SGGVRPFGISTLIVGFDTDGTPNLYQTDPSGSYSSWKAAAIGRSSKSVGEFLEKNY-TDV 182

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
           + +E+IKLA+ AL + +E  + +NIE+AVI  K +    L ++EI+K +  V  E E ++
Sbjct: 183 SEEESIKLAVRALLEIVESGN-KNIEIAVIRNK-QPIVLLDEQEIDKLVAVVEAEKEIQK 240

Query: 246 VKEKEE 251
            +EK E
Sbjct: 241 EQEKSE 246


>pir||T48679 proteasome alpha-2 chain [validated] - Haloferax volcanii
           >gi|5833208|gb|AAD53405.1|AF126261_1 (AF126261) alpha-2
           subunit of 20S proteasome [Haloferax volcanii]
           Length = 249
           
 Score =  201 bits (506), Expect = 7e-51
 Identities = 109/243 (44%), Positives = 152/243 (61%), Gaps = 3/243 (1%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR  ++FSPDGR++QV YAREAVKRGA  +GV+  DGVVLA  +   S L+E ES EK+
Sbjct: 9   YDRGTSLFSPDGRIYQVEYAREAVKRGAPVLGVRTADGVVLAALRSTPSELMEAESIEKL 68

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            ++DD + AA++G +ADAR LV+ AR  AQ   L YGEP  +  + K I D  Q  TQ G
Sbjct: 69  HKLDDALGAATAGHVADARKLVDFARTTAQREHLRYGEPIGVETLTKTITDNIQESTQSG 128

Query: 130 GVRPFGAALLMAGV-NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
           G RP+GA+LL+ GV N    L+ TDPSG    WKAVAIG  R    A  ED Y +D++L+
Sbjct: 129 GTRPYGASLLIGGVENGSGRLFATDPSGTPQEWKAVAIGGHREDVQAALEDGYAEDLSLE 188

Query: 189 EAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVKE 248
           + + LA+ AL    E+   E+ E+ ++TV +  +  + +E I +   +   + E +E  E
Sbjct: 189 DGLALAVEALVAADEE--IESDELNLVTVSEAGYEIVDEETIAELFADATADDESDETDE 246

Query: 249 KEE 251
           +EE
Sbjct: 247 REE 249


>gb|AAC32061.1| (AF043525) 20S proteasome subunit PAE2 [Arabidopsis thaliana]
           >gi|9279577|dbj|BAB01035.1| (AB022220) 20S proteasome
           subunit PAE-like protein [Arabidopsis thaliana]
           Length = 237
           
 Score =  199 bits (501), Expect = 3e-50
 Identities = 106/211 (50%), Positives = 141/211 (66%), Gaps = 5/211 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+GVK K+GVVLAVEKRITS L+EP S EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKEGVVLAVEKRITSPLLEPSSVEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH---T 126
            +IDDHI  A SG+IADAR LV  AR+E Q HR +YGEP  +    + +CDL        
Sbjct: 68  MEIDDHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGE 127

Query: 127 QYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           +    RPFG +LL+AG ++  P LY TDPSG ++   A AIGSG   A +  ++++  D+
Sbjct: 128 EESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQFNKDI 187

Query: 186 TLDEAIKLAIFALAKTM-EKPSAENIEVAVI 215
           TL EA  +A+  L + M EK +  N+++A +
Sbjct: 188 TLQEAETIAVSILKQVMEEKVTPNNVDIAKV 218


>dbj|BAA95822.1| (AP002069) ESTs AU058081(E3082),AU075427(E30384) correspond to a
           region of the predicted gene.~Similar to Spinacia
           oleracea proteasome 27 kD subunit (P52427) [Oryza
           sativa] >gi|8096329|dbj|BAA95832.1| (AP002069) ESTs
           AU058081(E3082),AU075427(E30384) correspond to a region
           of the predicted gene.~Similar to Spinacia oleracea
           proteasome 27 kD subunit (P52427) [Oryza sativa]
           >gi|8671496|dbj|BAA96831.1| (AB026560) alpha 3 subunit
           of 20S proteasome [Oryza sativa]
           Length = 250
           
 Score =  199 bits (501), Expect = 3e-50
 Identities = 103/236 (43%), Positives = 157/236 (65%), Gaps = 9/236 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA EA+    +A+GV   DGVVL  EK++TS+L++   S EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAIGNAGSALGVLAADGVVLVGEKKVTSKLLQTSRSAEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +++ID H+A A +GI++DA +L+N ARL AQ + L+Y EP P+  +V+ +CD KQ +TQ+
Sbjct: 65  MYKIDSHLACAVAGIMSDANILLNTARLHAQRYALSYQEPIPVEQLVQSLCDTKQGYTQF 124

Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+RPFG + L AG +     +LY +DPSG Y  WKA A+G+    A ++ +  YRD MT
Sbjct: 125 GGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYSGWKAAAVGANSQAAQSMLKQDYRDGMT 184

Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITVK----DKKFRKLSKEEIEKFLGE 236
            +EA+ LA+  L+KTM+  S  AE +E+A + ++    + +++  S E + K L +
Sbjct: 185 REEAVALALKVLSKTMDSTSLTAEKLELAEVFLQPGTGEVQYQVCSPEAMGKLLAK 240


>gb|AAD31877.1|AF140353_1 (AF140353) 20S proteasome alpha 5 subunit [Trypanosoma brucei
           brucei]
           Length = 246
           
 Score =  199 bits (500), Expect = 3e-50
 Identities = 98/238 (41%), Positives = 151/238 (63%), Gaps = 7/238 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GR+FQ+ YA EA+K G+T++G++  D V++A EKR+ S L++P S  KI
Sbjct: 8   YDRGVNTFSPEGRIFQIEYAIEAIKLGSTSLGIQTPDAVIIAAEKRVPSTLVDPSSVNKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI    SG++ADAR+LV+ AR+EAQ HR TY EP  +       CDL     + G
Sbjct: 68  LEIDHHIGTVLSGMVADARILVDHARVEAQNHRFTYDEPMSVESCALATCDLSVQFGESG 127

Query: 130 G-----VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD 183
           G      RPFG +LL+AGV++  P+L++TDPSG Y  + A AIG G   A  +F ++Y  
Sbjct: 128 GRKKLMSRPFGVSLLIAGVDENGPQLWQTDPSGTYTRYDAQAIGGGAEAAQTVFSERYHR 187

Query: 184 DMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
           +MT++EA  L +  L + M EK +  ++E+A++ V   + +   +E+I++ +    +E
Sbjct: 188 NMTVEEAENLTVQILRQVMEEKLTKTSVEIAIVPVSTGRLQIYDQEQIQRIIDRQAEE 245


>dbj|BAA96832.1| (AB026561) alpha 5 subunit of 20S proteasome [Oryza sativa]
           Length = 237
           
 Score =  199 bits (500), Expect = 3e-50
 Identities = 105/212 (49%), Positives = 142/212 (66%), Gaps = 5/212 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+G+K KDGVVLAVEKR+TS L+EP S EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGLKTKDGVVLAVEKRVTSPLLEPSSVEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH---T 126
            +ID+HI  A SG+IADAR LV  AR+E Q HR +YGEP  +    + ICDL        
Sbjct: 68  MEIDEHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQAICDLALRFGEGD 127

Query: 127 QYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           +    RPFG +LL+AG ++  P LY TDPSG ++   A AIGSG   A +  +++Y  ++
Sbjct: 128 EESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQYNKEL 187

Query: 186 TLDEAIKLAIFALAKTM-EKPSAENIEVAVIT 216
           TL EA  +A+  L + M EK +  N+++A ++
Sbjct: 188 TLQEAETIALSILKQVMEEKVTPNNVDIAKVS 219


>gb|AAF89684.1|AF169652_1 (AF169652) 20S proteasome alpha 4 subunit [Trypanosoma brucei]
           Length = 247
           
 Score =  198 bits (499), Expect = 4e-50
 Identities = 108/248 (43%), Positives = 159/248 (63%), Gaps = 8/248 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRAITVFSPDG LFQV YA+EAV++G  AVGVK KD ++ AVEK+   +L +  +  KI
Sbjct: 3   YDRAITVFSPDGHLFQVEYAQEAVRKGLCAVGVKGKDSIIFAVEKKSVQKLQDSRTTRKI 62

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
           +++D+HI  AS+G+ ADARV+VN A+LE Q  RL+Y +   + ++V+ +  ++Q  TQ  
Sbjct: 63  YKLDEHIYLASAGLSADARVVVNHAQLECQRFRLSYEDAIDVDLLVRYVARVQQRSTQSS 122

Query: 130 GVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           G RP+G + ++ G N+  +P+L++T+PSG   AW A AIG      +   E  Y+D MT 
Sbjct: 123 GSRPYGVSTIIGGFNENGQPQLWKTEPSGTSSAWNAAAIGRNDKVVLEFMEKNYQDGMTR 182

Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
           D  +  AI AL + +E  S +NIE+ V+  +  K   +S  E+ +F+ EV KE EEE  +
Sbjct: 183 DRCVHFAIKALLEAVESGS-KNIELLVL--ERGKAAYMSDTELHRFVVEVEKEREEEAAR 239

Query: 248 EK---EED 252
            +   EED
Sbjct: 240 RRRLAEED 247


>gb|AAC32060.1| (AF043524) 20S proteasome subunit PAE1 [Arabidopsis thaliana]
           >gi|6056394|gb|AAF02858.1|AC009324_7 (AC009324) 20S
           proteasome subunit PAE1 [Arabidopsis thaliana]
           Length = 237
           
 Score =  198 bits (498), Expect = 6e-50
 Identities = 105/211 (49%), Positives = 141/211 (66%), Gaps = 5/211 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+GVK K+GVVLAVEKRITS L+EP S EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKEGVVLAVEKRITSPLLEPSSVEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH---T 126
            +IDDHI  A SG+IADAR LV  AR+E Q HR +YGEP  +    + +CDL        
Sbjct: 68  MEIDDHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGE 127

Query: 127 QYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           +    RPFG +LL+AG ++  P LY TDPSG ++   A AIGSG   A +  ++++  D+
Sbjct: 128 EESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQFNKDL 187

Query: 186 TLDEAIKLAIFALAKTM-EKPSAENIEVAVI 215
           +L EA  +A+  L + M EK +  N+++A +
Sbjct: 188 SLQEAETIAVSILKQVMEEKVTPNNVDIAKV 218


>dbj|BAA78755.1| (AB023482) ESTs AU058081(E30812),AU058365(E50679), AU030138(E50679)
           correspond to a region of the predicted gene.; Similar
           to Spinacia oleracea mRNA for proteasome 37kD
           subunit.(X96974) [Oryza sativa]
           Length = 250
           
 Score =  198 bits (498), Expect = 6e-50
 Identities = 102/236 (43%), Positives = 157/236 (66%), Gaps = 9/236 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA EA+    +A+GV   DGVVL  EK++TS+L++   S EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAIGNAGSALGVLAADGVVLVGEKKVTSKLLQTSRSAEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +++ID H+A A +GI++DA +L+N ARL AQ + L+Y EP P+  +V+ +CD KQ +TQ+
Sbjct: 65  MYKIDSHLACAVAGIMSDANILLNTARLHAQRYALSYQEPIPVEQLVQSLCDTKQGYTQF 124

Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+RPFG + L AG +     +LY +DPSG Y  WKA A+G+    A ++ +  YRD +T
Sbjct: 125 GGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYSGWKAAAVGANSQAAQSMLKQDYRDGLT 184

Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITVK----DKKFRKLSKEEIEKFLGE 236
            +EA+ LA+  L+KTM+  S  AE +E+A + ++    + +++  S E + K L +
Sbjct: 185 REEAVALALKVLSKTMDSTSLTAEKLELAEVFLQPGTGEVQYQVCSPEAMGKLLAK 240


>pir||T19775 hypothetical protein C36B1.4 - Caenorhabditis elegans
           >gi|3874776|emb|CAB02269.1| (Z80215) contains similarity
           to Pfam domain: PF00227 (Proteasome A-type and B-type),
           Score=181.5, E-value=4.3e-51, N=1~cDNA EST EMBL:M79843
           comes from this gene~cDNA EST yk89g4.5 comes from this
           gene~cDNA EST yk361a1.3 comes from this gene~cDNA EST
           yk3>
           Length = 253
           
 Score =  198 bits (497), Expect = 8e-50
 Identities = 115/249 (46%), Positives = 163/249 (65%), Gaps = 11/249 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRAIT+FSPDG LFQV YA+EAVK+G+TAVGV+ KD +V+ VEK+    L +  +  KI
Sbjct: 4   YDRAITIFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDCIVIGVEKKSIPALQDDRTIRKI 63

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             IDDH+  A +G+ ADARVLV+RAR+E Q ++LT  +P  +A I + I + KQ  TQ  
Sbjct: 64  HMIDDHVMLAFAGLSADARVLVDRARIECQSYKLTLEDPVTVAYISRYIANTKQRFTQSP 123

Query: 130 GVRPFGAALLMAGV--NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           G RPFG ++L+ G   +  P L++T+PSGAY+ + A A G G        E++Y ++ T+
Sbjct: 124 GRRPFGISMLIGGFDHDGTPRLFKTEPSGAYYEYVANATGRGEKPVREYLEEQYSEENTV 183

Query: 188 DEA--IKLAIFALAKTMEKPSAENIEVAVI-TVKDK-KFRKLSKEEIEKFLGEVMKEVEE 243
           DEA  +KL + +LA+ +  P ++NIE+AV+  V D+ + R LS EEIE  L    K VE 
Sbjct: 184 DEATTLKLVVKSLAQVV-PPGSQNIEIAVMKKVNDELQQRVLSTEEIEALL----KVVET 238

Query: 244 EEVKEKEED 252
           E V  + E+
Sbjct: 239 ERVAAEAEE 247


>gb|AAF34770.1|AF227625_1 (AF227625) proteasome 27 kDa subunit [Euphorbia esula]
           Length = 242
           
 Score =  197 bits (496), Expect = 1e-49
 Identities = 99/228 (43%), Positives = 152/228 (66%), Gaps = 8/228 (3%)

Query: 15  TVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEKIFQID 73
           T+FSP+GRL+QV YA EA+    TA+G+  KDGVVL  EK++TS+L++   S EK+++ID
Sbjct: 2   TIFSPEGRLYQVEYAMEAIGNAGTAIGILSKDGVVLVGEKKVTSKLLQTSTSTEKMYKID 61

Query: 74  DHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRP 133
           DH++ A +GI++DA +L+N AR++AQ +  +Y EP P+  +V+ +CD KQ +TQ+GG+RP
Sbjct: 62  DHVSCAVAGIMSDANILINTARVQAQRYYFSYQEPMPVEQLVQSLCDTKQGYTQFGGLRP 121

Query: 134 FGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAI 191
           FG + + AG   N   +LY +DPSG Y  WKA AIG+    A  + +  Y+D++T +EA+
Sbjct: 122 FGVSFIFAGWDKNFGFQLYTSDPSGNYGGWKAAAIGANNQAAQFMLKQDYKDEITREEAV 181

Query: 192 KLAIFALAKTMEKPS-----AENIEVAVITVKDKKFRKLSKEEIEKFL 234
           +LA+  L+KTM+  S      E  EV ++     K++  S E + K L
Sbjct: 182 QLALKVLSKTMDSTSLTSDKLELAEVFLLPSGKVKYQVCSPETVSKLL 229


>gi|6321574 proteasome component Y13; Pre9p [Saccharomyces cerevisiae]
           >gi|130875|sp|P23638|PRC9_YEAST PROTEASOME COMPONENT Y13
           (MACROPAIN SUBUNIT Y13) (PROTEINASE YSCE SUBUNIT 13)
           (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT Y13)
           >gi|67722|pir||SNBYY3 multicatalytic endopeptidase
           complex (EC 3.4.99.46) chain Y13 - yeast (Saccharomyces
           cerevisiae) >gi|172262|gb|AAA34907.1| (M63851)
           proteasome Y13 [Saccharomyces cerevisiae]
           >gi|506480|emb|CAA40054.1| (X56730) proteasome Y13
           subunit [Saccharomyces cerevisiae]
           >gi|1323225|emb|CAA97148.1| (Z72920) ORF YGR135w
           [Saccharomyces cerevisiae]
           Length = 258
           
 Score =  196 bits (492), Expect = 3e-49
 Identities = 97/250 (38%), Positives = 166/250 (65%), Gaps = 11/250 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA E++    TA+G+   DG+VLA E+++TS L+E + S EK
Sbjct: 6   YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +++++D IA A +G+ ADA +L+N AR+ AQ +  TY E  P+ ++V+++ D+KQ +TQ+
Sbjct: 66  LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125

Query: 129 GGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+RPFG + + AG +D+   +LY ++PSG Y  WKA+++G+  + A  + +  Y+DDM 
Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMK 185

Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVK-----DKKFRKLSK-EEIEKFLGE--VM 238
           +D+AI+LA+  L+KT +  +     +   T++      + ++K+ K +EI+  L +  + 
Sbjct: 186 VDDAIELALKTLSKTTDSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIKDILVKTGIT 245

Query: 239 KEVEEEEVKE 248
           K+ E+EE  E
Sbjct: 246 KKDEDEEADE 255


>gi|6324535 alpha-type of subunit of 20S proteasome; Pre6p [Saccharomyces
           cerevisiae] >gi|730374|sp|P40303|PRC6_YEAST PROTEASOME
           COMPONENT PRE6 (MACROPAIN SUBUNIT PRE6) (PROTEINASE YSCE
           SUBUNIT PRE6) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           SUBUNIT PRE6) >gi|2118150|pir||B55904 multicatalytic
           endopeptidase complex (EC 3.4.99.46) chain PRE6 - yeast
           (Saccharomyces cerevisiae) >gi|511905|gb|AAA34903.1|
           (L34348) proteasome alpha-subunit [Saccharomyces
           cerevisiae] >gi|1419833|emb|CAA99040.1| (Z74780) ORF
           YOL038w [Saccharomyces cerevisiae]
           Length = 254
           
 Score =  195 bits (490), Expect = 5e-49
 Identities = 102/251 (40%), Positives = 163/251 (64%), Gaps = 9/251 (3%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SY 66
           +GYDRA+++FSPDG +FQV YA EAVKRG  AVGVK K+ VVL  E+R T +L +   + 
Sbjct: 2   SGYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITP 61

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
            K+ +ID H+  + SG+ AD+R+L+ +AR+EAQ HRLT  +P  +  + + +  ++Q +T
Sbjct: 62  SKVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYT 121

Query: 127 QYGGVRPFGAALLMAGV---NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DK 180
           Q GGVRPFG + L+AG    +D+P+LY+T+PSG Y +W A  IG    T     E   D+
Sbjct: 122 QSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDR 181

Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
                T++E +KL + +L + ++   A+NIE+ V+   D     LS EEI +++ ++ +E
Sbjct: 182 KEPPATVEECVKLTVRSLLEVVQ-TGAKNIEITVVK-PDSDIVALSSEEINQYVTQIEQE 239

Query: 241 VEEEEVKEKEE 251
            +E++ ++K++
Sbjct: 240 KQEQQEQDKKK 250


>gb|AAF70292.1|AF255338_1 (AF255338) 20S proteasome subunit [Glycine max]
           Length = 237
           
 Score =  195 bits (490), Expect = 5e-49
 Identities = 103/211 (48%), Positives = 140/211 (65%), Gaps = 5/211 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+G+K K+GVVLAVEKRITS L+EP S EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGLKTKEGVVLAVEKRITSPLLEPSSVEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH---T 126
            +ID+HI  A SG+IADAR LV  AR+E Q HR +YGEP  +    + +CDL        
Sbjct: 68  MEIDEHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGD 127

Query: 127 QYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           +    RPFG +LL+AG ++  P LY TDPSG ++     AIGSG   A +  ++++  D+
Sbjct: 128 EESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNGKAIGSGSEGADSSLQEQFNKDL 187

Query: 186 TLDEAIKLAIFALAKTM-EKPSAENIEVAVI 215
           TL EA  +A+  L + M EK +  N+++A +
Sbjct: 188 TLQEAETIALSILKQVMEEKVTPNNVDIAKV 218


>pir||T38639 proteasome component PUP2 homolog - fission yeast
           (Schizosaccharomyces pombe) >gi|5777696|emb|CAB53405.1|
           (AL109988) proteasome component PUP2 homolog
           [Schizosaccharomyces pombe]
           Length = 247
           
 Score =  192 bits (484), Expect = 3e-48
 Identities = 103/220 (46%), Positives = 143/220 (64%), Gaps = 14/220 (6%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+GVK KD VVL VEKR+TS L+E  S EK+
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKDAVVLGVEKRLTSPLMESHSVEKL 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
           F+ID HI  A SG+ ADAR ++  AR++ Q HR TY EP  +    + ICDL     ++G
Sbjct: 68  FEIDSHIGCAISGLTADARTIIEHARVQTQNHRFTYDEPQGIESTTQSICDLA---LRFG 124

Query: 130 G---------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFED 179
                      RPFG ALL+AG+++  P+LY ++PSG YF ++A AIGSG   A +    
Sbjct: 125 EGEDGEERIMSRPFGVALLIAGIDEHGPQLYHSEPSGTYFRYEAKAIGSGSEPAKSELVK 184

Query: 180 KYRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVK 218
           ++  DMTL+EA  L +  L + M EK  ++N+++A +T +
Sbjct: 185 EFHKDMTLEEAEVLILKVLRQVMEEKLDSKNVQLAKVTAE 224


>pdb|1G65|B Chain B, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
           Molecular Basis For Selectivity Of
           Alpha,Beta-Epoxyketone Proteasome Inhibitors
           >gi|11513428|pdb|1G65|P Chain P, Crystal Structure Of
           Epoxomicin:20s Proteasome Reveals A Molecular Basis For
           Selectivity Of Alpha,Beta-Epoxyketone Proteasome
           Inhibitors >gi|3114271|pdb|1RYP|C Chain C, Crystal
           Structure Of The 20s Proteasome From Yeast At 2.4
           Angstroms Resolution >gi|3114285|pdb|1RYP|Q Chain Q,
           Crystal Structure Of The 20s Proteasome From Yeast At
           2.4 Angstroms Resolution
           Length = 244
           
 Score =  192 bits (483), Expect = 3e-48
 Identities = 89/211 (42%), Positives = 147/211 (69%), Gaps = 5/211 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA E++    TA+G+   DG+VLA E+++TS L+E + S EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +++++D IA A +G+ ADA +L+N AR+ AQ +  TY E  P+ ++V+++ D+KQ +TQ+
Sbjct: 65  LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 124

Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+RPFG + + AG +D+   +LY ++PSG Y  WKA+++G+  + A  + +  Y+DDM 
Sbjct: 125 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMK 184

Query: 187 LDEAIKLAIFALAKTMEKPSA--ENIEVAVI 215
           +D+AI+LA+  L+KT +  +   + +E A I
Sbjct: 185 VDDAIELALKTLSKTTDSSALTYDRLEFATI 215


>pdb|1G0U|B Chain B, A Gated Channel Into The Proteasome Core Particle
           >gi|11514007|pdb|1G0U|P Chain P, A Gated Channel Into
           The Proteasome Core Particle
           Length = 245
           
 Score =  192 bits (483), Expect = 3e-48
 Identities = 89/211 (42%), Positives = 147/211 (69%), Gaps = 5/211 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA E++    TA+G+   DG+VLA E+++TS L+E + S EK
Sbjct: 6   YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +++++D IA A +G+ ADA +L+N AR+ AQ +  TY E  P+ ++V+++ D+KQ +TQ+
Sbjct: 66  LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125

Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+RPFG + + AG +D+   +LY ++PSG Y  WKA+++G+  + A  + +  Y+DDM 
Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMK 185

Query: 187 LDEAIKLAIFALAKTMEKPSA--ENIEVAVI 215
           +D+AI+LA+  L+KT +  +   + +E A I
Sbjct: 186 VDDAIELALKTLSKTTDSSALTYDRLEFATI 216


>sp|Q10329|PRC6_SCHPO PUTATIVE PROTEASOME COMPONENT PRE6 (MACROPAIN SUBUNIT)
           (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT)
           >gi|7492853|pir||T37985 proteasome component SPBC106.16
           - fission yeast  (Schizosaccharomyces pombe)
           >gi|7493192|pir||T39273 proteasome component SPBC106.16
           - fission yeast (Schizosaccharomyces pombe)
           >gi|1216254|emb|CAA93796.1| (Z69909) putative proteasome
           component [Schizosaccharomyces pombe]
           >gi|5817282|emb|CAB53732.1| (AL110295) proteasome
           component; PROS28 family [Schizosaccharomyces pombe]
           Length = 259
           
 Score =  191 bits (480), Expect = 8e-48
 Identities = 95/246 (38%), Positives = 160/246 (64%), Gaps = 7/246 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           +GYDRA++VFSPDGRL QV Y +EAV+RG TA+ ++  + +V+ VE++   +L    +++
Sbjct: 2   SGYDRALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQ 61

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           KI  +D+H+  A +G+ ADAR+L+++AR+EAQ H+L   +P  +  + + +  ++Q +TQ
Sbjct: 62  KIAMVDNHVCLAFAGLNADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYTQ 121

Query: 128 YGGVRPFGAALLMAGV---NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
            GGVRPFG + L+AG    ++ P +Y+T+P+G Y AWKA AIG     A    E  +++ 
Sbjct: 122 SGGVRPFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNWKEG 181

Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITV-KDKKFRKLSKEEIEKFLGEVMKEVEE 243
           ++ DE I LA+ +L + ++  S  NIE+A++   KD +F  L  ++I+  + E+  E E 
Sbjct: 182 LSRDETIHLAVSSLLEVVQTASG-NIELAIMDPGKDVEF--LHSDKIDTIVKEIQDEKEA 238

Query: 244 EEVKEK 249
           E  ++K
Sbjct: 239 EAARKK 244


>pdb|1G0U|C Chain C, A Gated Channel Into The Proteasome Core Particle
           >gi|11514008|pdb|1G0U|Q Chain Q, A Gated Channel Into
           The Proteasome Core Particle
           Length = 243
           
 Score =  191 bits (480), Expect = 8e-48
 Identities = 101/244 (41%), Positives = 157/244 (63%), Gaps = 9/244 (3%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SY 66
           +GYDRA+++FSPDG +FQV YA EAVKRG  AVGVK K+ VVL  E+R T +L +   + 
Sbjct: 2   SGYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITP 61

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
            K+ +ID H+  + SG+ AD+R+L+ +AR+EAQ HRLT  +P  +  + + +  ++Q +T
Sbjct: 62  SKVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYT 121

Query: 127 QYGGVRPFGAALLMAGV---NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DK 180
           Q GGVRPFG + L+AG    +D+P+LY+T+PSG Y +W A  IG    T     E   D+
Sbjct: 122 QSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDR 181

Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
                T++E +KL + +L + ++   A+NIE+ V+   D     LS EEI +++ ++ +E
Sbjct: 182 KEPPATVEECVKLTVRSLLEVVQ-TGAKNIEITVVK-PDSDIVALSSEEINQYVTQIEQE 239

Query: 241 VEEE 244
            +E+
Sbjct: 240 KQEQ 243


>pdb|1G65|C Chain C, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
           Molecular Basis For Selectivity Of
           Alpha,Beta-Epoxyketone Proteasome Inhibitors
           >gi|11513429|pdb|1G65|Q Chain Q, Crystal Structure Of
           Epoxomicin:20s Proteasome Reveals A Molecular Basis For
           Selectivity Of Alpha,Beta-Epoxyketone Proteasome
           Inhibitors >gi|3114272|pdb|1RYP|D Chain D, Crystal
           Structure Of The 20s Proteasome From Yeast At 2.4
           Angstroms Resolution >gi|3114286|pdb|1RYP|R Chain R,
           Crystal Structure Of The 20s Proteasome From Yeast At
           2.4 Angstroms Resolution
           Length = 241
           
 Score =  190 bits (479), Expect = 1e-47
 Identities = 101/243 (41%), Positives = 156/243 (63%), Gaps = 9/243 (3%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYE 67
           GYDRA+++FSPDG +FQV YA EAVKRG  AVGVK K+ VVL  E+R T +L +   +  
Sbjct: 1   GYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPS 60

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           K+ +ID H+  + SG+ AD+R+L+ +AR+EAQ HRLT  +P  +  + + +  ++Q +TQ
Sbjct: 61  KVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQ 120

Query: 128 YGGVRPFGAALLMAGV---NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DKY 181
            GGVRPFG + L+AG    +D+P+LY+T+PSG Y +W A  IG    T     E   D+ 
Sbjct: 121 SGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRK 180

Query: 182 RDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEV 241
               T++E +KL + +L + ++   A+NIE+ V+   D     LS EEI +++ ++ +E 
Sbjct: 181 EPPATVEECVKLTVRSLLEVVQ-TGAKNIEITVVK-PDSDIVALSSEEINQYVTQIEQEK 238

Query: 242 EEE 244
           +E+
Sbjct: 239 QEQ 241


>sp|Q09682|PRC9_SCHPO PUTATIVE PROTEASOME COMPONENT C9/Y13 (MACROPAIN SUBUNIT)
           (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT)
           >gi|2118147|pir||S58093 probable multicatalytic
           endopeptidase complex (EC 3.4.99.46) chain SPA13C5.01c -
           fission yeast (Schizosaccharomyces pombe)
           >gi|908890|emb|CAA90452.1| (Z50112) proteasome component
           y13 [Schizosaccharomyces pombe]
           Length = 248
           
 Score =  190 bits (477), Expect = 2e-47
 Identities = 98/241 (40%), Positives = 153/241 (62%), Gaps = 5/241 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA EA+     A+G+  KDG+VLA EK++TS+L+E E S EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYALEAINHAGVALGIVAKDGIVLAAEKKVTSKLLEQEESAEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           ++ I D++  A +G+ ADA +L+N AR   Q +  T+ E  P   +V+++CDLKQ +TQY
Sbjct: 65  LYHIGDNMLCAVAGLTADANILINYARRVGQQYLQTFNEEMPCEQLVRRVCDLKQGYTQY 124

Query: 129 GGVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG+RPFG + L AG +     +L++++PSG Y +W+A +IG    +  ++   +Y+DD+ 
Sbjct: 125 GGLRPFGVSFLYAGWDHIRGYQLFQSNPSGNYGSWQANSIGGNSTSVQSLMRQEYKDDIN 184

Query: 187 LDEAIKLAIFALAKTMEKPSA--ENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
           LDEA  +A+  L+KT++  S   E IE A IT    K + + K      + EV+ + +E 
Sbjct: 185 LDEASAMAVKFLSKTLDSNSLTHEKIEFATITKDTTKNKMVCKIWKSDEINEVLNKYQET 244

Query: 245 E 245
           +
Sbjct: 245 Q 245


>gi|4506185 proteasome (prosome, macropain) subunit, alpha type, 4 [Homo
           sapiens] >gi|11431712|ref|XP_007578.1| proteasome
           (prosome, macropain) subunit, alpha type, 4 [Homo
           sapiens] >gi|130861|sp|P25789|PRC9_HUMAN PROTEASOME
           COMPONENT C9 (MACROPAIN SUBUNIT C9) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C9) >gi|67720|pir||SNHUC9
           multicatalytic endopeptidase complex (EC 3.4.99.46)
           chain C9 - human >gi|220030|dbj|BAA00660.1| (D00763)
           proteasome subunit C9 [Homo sapiens]
           Length = 261
           
 Score =  189 bits (476), Expect = 2e-47
 Identities = 106/257 (41%), Positives = 164/257 (63%), Gaps = 10/257 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
           YD   T+FSP+GRL+QV YA EA+    T +G+   DGV+LA E+R   +L++   + EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I+++++ +A + +GI +DA VL N  RL AQ + L Y EP P   +V  +CD+KQ +TQ+
Sbjct: 65  IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124

Query: 129 GGVRPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-D 184
           GG RPFG +LL  G  DK    +LY++DPSG Y  WKA  IG+    A+++ +  Y++ +
Sbjct: 125 GGKRPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGE 183

Query: 185 MTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMKE 240
           MTL  A+ LAI  L KTM+  K SAE +E+A +T ++ K   R L ++E+E+ + +  +E
Sbjct: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEE 243

Query: 241 VEEEEVKEKEEDYSELD 257
             + E ++KE++  E D
Sbjct: 244 EAKAEREKKEKEQKEKD 260


>pir||S17521 multicatalytic endopeptidase complex (EC 3.4.99.46) zeta chain -
           human
           Length = 241
           
 Score =  189 bits (475), Expect = 3e-47
 Identities = 106/238 (44%), Positives = 149/238 (62%), Gaps = 14/238 (5%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+G++  +GV LAVEKRITS L+EP S EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI  A SG+IADA+ L+++AR+E Q H  TY E   +  + + + +L     Q+G
Sbjct: 68  VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124

Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
                     RPFG ALL  GV++K P+L+  DPSG +    A AIGS    A +  ++ 
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEL 184

Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           Y   MTL EAIK ++  L + M EK +A NIE+A +    + F   +KEE+E+ + ++
Sbjct: 185 YHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241


>gi|7106387 proteasome (prosome, macropain) subunit, alpha type 5 [Mus
           musculus] >gi|3805976|gb|AAC69149.1| (AF019661) zeta
           proteasome chain; PSMA5 [Mus musculus]
           Length = 241
           
 Score =  189 bits (475), Expect = 3e-47
 Identities = 106/238 (44%), Positives = 149/238 (62%), Gaps = 14/238 (5%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+G++  +GV LAVEKRITS L+EP S EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI  A SG+IADA+ L+++AR+E Q H  TY E   +  + + + +L     Q+G
Sbjct: 68  VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124

Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
                     RPFG ALL  GV++K P+L+  DPSG +    A AIGS    A +  ++ 
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEV 184

Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           Y   MTL EAIK ++  L + M EK +A NIE+A +    + F   +KEE+E+ + ++
Sbjct: 185 YHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241


>gi|8394069 proteasome (prosome, macropain) subunit, alpha type 4 [Rattus
           norvegicus] >gi|130862|sp|P21670|PRC9_RAT PROTEASOME
           COMPONENT C9 (MACROPAIN SUBUNIT C9) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C9) (PROTEASOME SUBUNIT L)
           >gi|67721|pir||SNRTC9 multicatalytic endopeptidase
           complex (EC 3.4.99.46) chain C9 - rat
           >gi|56641|emb|CAA39458.1| (X55986) multicatalytic
           proteinase subunit L [Rattus rattus]
           >gi|57000|emb|CAA37390.1| (X53304) unnamed protein
           product [Rattus norvegicus]
           Length = 261
           
 Score =  189 bits (474), Expect = 4e-47
 Identities = 105/257 (40%), Positives = 164/257 (62%), Gaps = 10/257 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
           YD   T+FSP+GRL+QV YA EA+    T +G+   DGV+LA E+R   +L++   + EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I+++++ +A + +GI +DA VL N  RL AQ + L Y EP P   +V  +CD+KQ +TQ+
Sbjct: 65  IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124

Query: 129 GGVRPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-D 184
           GG RPFG +LL  G  DK    +LY++DPSG Y  WKA  IG+    A+++ +  Y++ +
Sbjct: 125 GGKRPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGE 183

Query: 185 MTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMKE 240
           MTL  A+ LA+  L KTM+  K SAE +E+A +T ++ K   R L ++E+E+ + +  +E
Sbjct: 184 MTLKSALALAVKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEE 243

Query: 241 VEEEEVKEKEEDYSELD 257
             + E ++KE++  E D
Sbjct: 244 EAKAEREKKEKEQREKD 260


>gi|6755196 proteasome (prosome, macropain) subunit, alpha type 4 [Mus
           musculus] >gi|9910830|sp|Q9R1P0|PRC9_MOUSE PROTEASOME
           COMPONENT C9 (MACROPAIN SUBUNIT C9) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C9)
           >gi|5757663|gb|AAD50538.1|AF060093_1 (AF060093)
           proteasome subunit C9 [Mus musculus]
           Length = 261
           
 Score =  188 bits (473), Expect = 5e-47
 Identities = 105/257 (40%), Positives = 163/257 (62%), Gaps = 10/257 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
           YD   T+FSP+GRL+QV YA EA+    T +G+   DGV+LA E+R   +L++   + EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I+++++ +A + +GI +DA VL N  RL AQ + L Y EP P   +V  +CD+KQ +TQ+
Sbjct: 65  IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124

Query: 129 GGVRPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-D 184
           GG RPFG +LL  G  DK    +LY++DPSG Y  WKA  IG+    A+++ +  Y++ +
Sbjct: 125 GGKRPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGE 183

Query: 185 MTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMKE 240
           MTL  A+ LA+  L KTM+  K SAE +E+A +T +  K   R L ++E+E+ + +  +E
Sbjct: 184 MTLKSALALAVKVLNKTMDVSKLSAEKVEIATLTRESGKTVIRVLKQKEVEQLIKKHEEE 243

Query: 241 VEEEEVKEKEEDYSELD 257
             + E ++KE++  E D
Sbjct: 244 EAKAEREKKEKEQREKD 260


>sp|Q95083|PRCZ_DROME PROTEASOME PSMA5 SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           PSMA5 CHAIN) >gi|1498589|gb|AAB93421.1| (U64721) 20S
           proteasome alpha subunit PSMA5 [Drosophila melanogaster]
           Length = 244
           
 Score =  188 bits (472), Expect = 7e-47
 Identities = 103/237 (43%), Positives = 147/237 (61%), Gaps = 10/237 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+G+   +GVVLAVEKRITS L+ P + EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            ++D HI  A+SG++ADAR L+ RAR+E Q H   Y E   +    + +  L       G
Sbjct: 68  VEVDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSG 127

Query: 130 G-------VRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
                    RPFG A+L AG+   +P+L+  DPSG +    A AIGSG   A    +D +
Sbjct: 128 DSDGAAAMSRPFGVAILFAGIEAGQPQLWHMDPSGTFVGHGAKAIGSGSEGAQQNLQDLF 187

Query: 182 RDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           R D+TLDEAI +++  L + M EK ++ N+EV  +T K+++F   +KEE+E+ +  +
Sbjct: 188 RPDLTLDEAIDISLNTLKQVMEEKLNSTNVEVMTMT-KEREFYMFTKEEVEQHIKNI 243


>gb|AAF57875.1| (AE003803) ProsMA5 gene product [Drosophila melanogaster]
           Length = 244
           
 Score =  187 bits (471), Expect = 9e-47
 Identities = 103/237 (43%), Positives = 147/237 (61%), Gaps = 10/237 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+G+   +GVVLAVEKRITS L+ P + EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            ++D HI  A+SG++ADAR L+ RAR+E Q H   Y E   +    + +  L       G
Sbjct: 68  VEVDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSG 127

Query: 130 G-------VRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
                    RPFG A+L AG+   +P+L+  DPSG +    A AIGSG   A    +D +
Sbjct: 128 DSDGAAAMSRPFGVAILFAGIEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLF 187

Query: 182 RDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           R D+TLDEAI +++  L + M EK ++ N+EV  +T K+++F   +KEE+E+ +  +
Sbjct: 188 RPDLTLDEAIDISLNTLKQVMEEKLNSTNVEVMTMT-KEREFYMFTKEEVEQHIKNI 243


>sp|O73672|PRC3_CARAU PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C3) (PROTEASOME ALPHA-2
           SUBUNIT) >gi|3107927|dbj|BAA25915.1| (AB013342)
           proteasome alpha 2 subunit [Carassius auratus]
           Length = 234
           
 Score =  187 bits (470), Expect = 1e-46
 Identities = 102/231 (44%), Positives = 144/231 (62%), Gaps = 4/231 (1%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GY  ++T FSP G+L Q+ YA  AV  GA +VG+K  +GVVLA EK+  S L + +S  K
Sbjct: 5   GYSFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKASNGVVLATEKKQKSILYDEQSVHK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  I  HI    SG+  D RVLV RAR  AQ + L Y EP P   +V+++  + Q +TQ 
Sbjct: 65  IEPITKHIGMVYSGMGPDYRVLVRRARKLAQQYFLVYQEPIPTGQLVQRVASVMQEYTQS 124

Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           GGVRPFG +LL+AG + D+P L+++DPSGAYFAWKA A+G          E +Y +D+ L
Sbjct: 125 GGVRPFGVSLLIAGWDEDRPYLFQSDPSGAYFAWKATAMGKSYVNGKTFLEKRYNEDLEL 184

Query: 188 DEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           ++AI  AI  L ++ E + + ENIEV +    +  FR+LS  E++ +L  +
Sbjct: 185 EDAIHTAILTLKESFEGQMTEENIEVGI--CNEAGFRRLSPAEVKDYLAAI 233


>pir||S38530 multicatalytic endopeptidase complex (EC 3.4.99.46) chain XC9
           (clone 1) - clawed frog
           Length = 261
           
 Score =  187 bits (470), Expect = 1e-46
 Identities = 110/261 (42%), Positives = 164/261 (62%), Gaps = 18/261 (6%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
           YD   T+FSP+GRL+QV YA EA+    T +G+   DGV+LA E+R   +L++   + EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDDVFFSEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I++++D +A + +GI +DA VL N  RL AQ + L Y EP P   +V  +CD+KQ +TQ+
Sbjct: 65  IYKLNDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124

Query: 129 GGVRPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-D 184
           GG RPFG +LL  G  DK    +LY++DPSG Y  WKA  IG+    A+++ +  Y++  
Sbjct: 125 GGKRPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGG 183

Query: 185 MTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKD--KKFRKLSKEEIEKFLGEVMKE 240
           MTL  A+ LA+  L KTM+  K SAE +E+A +T ++   K R L ++E+E    E++K 
Sbjct: 184 MTLKSALALAVKVLNKTMDVSKLSAEKVELATLTRENGKTKIRVLQQKEVE----ELIKL 239

Query: 241 VEEEEVK----EKEEDYSELD 257
            EEEE K    +K+++  E D
Sbjct: 240 HEEEEAKIEREKKDKEQKEKD 260


>gi|4506187 proteasome (prosome, macropain) subunit, alpha type, 5; Proteasome
           component 5 [Homo sapiens]
           >gi|464456|sp|P28066|PRCZ_HUMAN PROTEASOME ZETA CHAIN
           (MACROPAIN ZETA CHAIN) (MULTICATALYTIC ENDOPEPTIDASE
           COMPLEX ZETA CHAIN) >gi|296740|emb|CAA43962.1| (X61970)
           macropain subunit zeta [Homo sapiens]
           Length = 241
           
 Score =  187 bits (469), Expect = 1e-46
 Identities = 105/238 (44%), Positives = 148/238 (62%), Gaps = 14/238 (5%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV Y  EA+K G+TA+G++  +GV LAVEKRITS L+EP S EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYDIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI  A SG+IADA+ L+++AR+E Q H  TY E   +  + + + +L     Q+G
Sbjct: 68  VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124

Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
                     RPFG ALL  GV++K P+L+  DPSG +    A AIGS    A +  ++ 
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEL 184

Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           Y   MTL EAIK ++  L + M EK +A NIE+A +    + F   +KEE+E+ + ++
Sbjct: 185 YHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241


>pir||T40971 20s proteasome component C3 - fission yeast  (Schizosaccharomyces
           pombe) >gi|3790251|emb|CAA21440.1| (AL031966) 20s
           proteasome component C3 [Schizosaccharomyces pombe]
           Length = 245
           
 Score =  186 bits (468), Expect = 2e-46
 Identities = 105/241 (43%), Positives = 147/241 (60%), Gaps = 13/241 (5%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           Y  ++T FSP+G+L Q+ YA  AV  G T+VG+K  DGVVLA EK+ TS L    S EK+
Sbjct: 5   YAFSLTTFSPNGKLVQIEYALNAVNAGVTSVGIKATDGVVLATEKKPTSELAIGASLEKV 64

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQ-IHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
             I   I    SG+  D RVLV+++R  AQ  ++  Y E  P  ++V++I  + Q  TQ 
Sbjct: 65  CAITPDIGMVYSGMGPDFRVLVDKSRKVAQTTYKKIYNEYPPTKILVQEIASVMQESTQS 124

Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           GGVRPFG +LL+AG+++K P LY+ DPSG YFAWKA AIG     A    E +Y D++ L
Sbjct: 125 GGVRPFGVSLLVAGMDEKGPSLYQVDPSGTYFAWKATAIGKSSTAAKTFLEKRYNDELEL 184

Query: 188 DEAIKLAIFALAKTME-KPSAENIEVAVITVKDK----------KFRKLSKEEIEKFLGE 236
           D+A+  AI AL +T E + + +NIE+AV++ K             F +LS+ EI  +L +
Sbjct: 185 DDAVHTAILALKETFEGELTEDNIEIAVVSTKPTDSGIVGVPGGHFCRLSQSEIRDYLDQ 244

Query: 237 V 237
           V
Sbjct: 245 V 245


>sp|P34119|PRC9_DICDI PROTEASOME SUBUNIT DD4 (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
           SUBUNIT DD4) >gi|347509|gb|AAA33233.1| (L22212)
           proteasome [Dictyostelium discoideum]
           Length = 250
           
 Score =  186 bits (467), Expect = 3e-46
 Identities = 98/246 (39%), Positives = 156/246 (62%), Gaps = 11/246 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY--E 67
           YD+  T+FSP+GR++QV YA  A++     VG+  KDG+VLA EK+ T++L++  +   E
Sbjct: 5   YDQRTTIFSPEGRVYQVEYAMTAIRHAGATVGILAKDGIVLAAEKKTTAKLLDSSTSISE 64

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           K+F+ID+H+  A +GI +DA +L+N ARL +Q     Y EP P+  +V +ICD KQ +TQ
Sbjct: 65  KMFKIDEHVVCAVAGITSDANILINYARLSSQRFFYQYQEPMPVEQLVSQICDTKQGYTQ 124

Query: 128 YGGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNT--AMAIFEDKYRD 183
           YGG+RPFG + L AG +     +LY++DPSG +  WKA +IG G N+  A ++    Y+ 
Sbjct: 125 YGGLRPFGVSFLYAGWDRHYGFQLYQSDPSGNFAGWKATSIG-GENSQVAQSVLRSNYKP 183

Query: 184 DMTLDEAIKLAIFALAKTMEKP--SAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMK 239
           D++L EA++LA+  L KTM++   ++E +E +  T +     +   +  E++ F+ E   
Sbjct: 184 DISLKEALQLALKVLTKTMDRSNINSEKLEFSYFTKQGDNVVYHIFTAAELDAFIKETDL 243

Query: 240 EVEEEE 245
           E E E+
Sbjct: 244 EQETED 249


>sp|P22769|PRC6_DROME PROTEASOME 28 KD SUBUNIT 1 (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 28
           KD SUBUNIT 1) >gi|85119|pir||JQ0681 proteasome chain 1 -
           fruit fly (Drosophila melanogaster)
           >gi|158186|gb|AAA62768.1| (M57712) proteasome
           beta-subunit [Drosophila melanogaster]
           Length = 249
           
 Score =  185 bits (464), Expect = 6e-46
 Identities = 101/246 (41%), Positives = 151/246 (61%), Gaps = 6/246 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRA+T+FSPDG L QV YA+EAV++G+TAVGV+  + VVL VEK+  ++L E     KI
Sbjct: 5   YDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKI 64

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +D+H+  A +G+ ADAR+++NRA++E Q HRL   +P  L  I + I  LKQ +TQ  
Sbjct: 65  CMLDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSN 124

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           G RPFG + L+ G   +    L++T+PSG ++ +KA A G         FE  YR++   
Sbjct: 125 GRRPFGISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVA 184

Query: 188 DE--AIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
           +E  A+KLAI AL +  +     N+EVA++    K  + L  + I  ++  + KE EEE 
Sbjct: 185 NEHGAVKLAIRALLEVAQS-GQNNLEVAIME-NGKPLKMLDNDVITDYVKIIEKEKEEEL 242

Query: 246 VKEKEE 251
            K+K++
Sbjct: 243 EKKKQK 248


>pir||S23451 multicatalytic endopeptidase complex (EC 3.4.99.46) 28K chain -
           fruit fly (Drosophila melanogaster)
           >gi|8386|emb|CAA44174.1| (X62286) 28 KDa proteasome
           subunit [Drosophila melanogaster]
           >gi|7293190|gb|AAF48573.1| (AE003501) Pros28.1 gene
           product [Drosophila melanogaster]
           Length = 249
           
 Score =  184 bits (463), Expect = 7e-46
 Identities = 101/246 (41%), Positives = 151/246 (61%), Gaps = 6/246 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRA+T+FSPDG L QV YA+EAV++G+TAVGV+  + VVL VEK+  ++L E     KI
Sbjct: 5   YDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKI 64

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +D+H+  A +G+ ADAR+++NRA++E Q HRL   +P  L  I + I  LKQ +TQ  
Sbjct: 65  CMLDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSN 124

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           G RPFG + L+ G   +    L++T+PSG ++ +KA A G         FE  YR++   
Sbjct: 125 GRRPFGISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVA 184

Query: 188 DE--AIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
           +E  A+KLAI AL +  +     N+EVA++    K  + L  + I  ++  + KE EEE 
Sbjct: 185 NEHGAVKLAIRALLEVAQS-GQNNLEVAIME-NGKPLKMLDTDVITDYVKIIEKEKEEEL 242

Query: 246 VKEKEE 251
            K+K++
Sbjct: 243 EKKKQK 248


>gi|4506181 proteasome (prosome, macropain) subunit, alpha type, 2 [Homo
           sapiens] >gi|11421228|ref|XP_004888.1| similar to
           proteasome (prosome, macropain) subunit, alpha type, 2
           (H. sapiens) [Homo sapiens]
           >gi|130850|sp|P25787|PRC3_HUMAN PROTEASOME COMPONENT C3
           (MACROPAIN SUBUNIT C3) (MULTICATALYTIC ENDOPEPTIDASE
           COMPLEX SUBUNIT C3) >gi|67725|pir||SNHUC3 multicatalytic
           endopeptidase complex (EC 3.4.99.46) chain C3 - human
           >gi|220024|dbj|BAA00657.1| (D00760) proteasome subunit
           C3 [Homo sapiens]
           Length = 234
           
 Score =  184 bits (463), Expect = 7e-46
 Identities = 99/233 (42%), Positives = 145/233 (61%), Gaps = 4/233 (1%)

Query: 7   QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           + GY  ++T FSP G+L Q+ YA  AV  GA +VG+K  +GVVLA EK+  S L +  S 
Sbjct: 3   ERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSV 62

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
            K+  I  HI    SG+  D RVLV+RAR  AQ + L Y EP P A +V+++  + Q +T
Sbjct: 63  HKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYT 122

Query: 127 QYGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           Q GGVRPFG +LL+ G N+ +P L+++DPSGAYFAWKA A+G          E +Y +D+
Sbjct: 123 QSGGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDL 182

Query: 186 TLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
            L++AI  AI  L ++ E + + +NIEV +    +  FR+L+  E++ +L  +
Sbjct: 183 ELEDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFRRLTPTEVKDYLAAI 233


>sp|O23708|PRC3_ARATH PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C3)
           >gi|2511574|emb|CAA73619.1| (Y13176) multicatalytic
           endopeptidase [Arabidopsis thaliana]
           >gi|3421075|gb|AAC32056.1| (AF043520) 20S proteasome
           subunit PAB1 [Arabidopsis thaliana]
           >gi|4966368|gb|AAD34699.1|AC006341_27 (AC006341)
           Identical to gb|Y13176 Arabidopsis thaliana mRNA for
           proteasome subunit prc3.  ESTs gb|H36972, gb|T22551 and
           gb|T13800 come from this gene
           Length = 235
           
 Score =  184 bits (463), Expect = 7e-46
 Identities = 99/230 (43%), Positives = 147/230 (63%), Gaps = 3/230 (1%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           Y  ++T FSP G+L Q+ +A  AV  G T++G+K  +GVV+A EK++ S L++  S +KI
Sbjct: 6   YSFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKASNGVVIATEKKLPSILVDEASVQKI 65

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +  +I    SG+  D RVLV ++R +A+ +   Y EP P+  +V++   + Q  TQ G
Sbjct: 66  QHLTPNIGVVYSGMGPDFRVLVRKSRKQAEQYLRLYKEPIPVTQLVRETATVMQEFTQSG 125

Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
           GVRPFG +LL+AG +DK P+LY+ DPSG+YF+WKA A+G   + A    E +Y +DM LD
Sbjct: 126 GVRPFGVSLLVAGYDDKGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMELD 185

Query: 189 EAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           +AI  AI  L +  E + S++NIE+  I   DK FR L+  EI+ +L EV
Sbjct: 186 DAIHTAILTLKEGFEGEISSKNIEIGKIGA-DKVFRVLTPAEIDDYLAEV 234


>gi|11428206 proteasome (prosome, macropain) subunit, alpha type, 5 [Homo
           sapiens]
           Length = 241
           
 Score =  184 bits (463), Expect = 7e-46
 Identities = 105/238 (44%), Positives = 148/238 (62%), Gaps = 14/238 (5%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EA+K G+TA+G++  +GV LAVEKRITS L+EP S EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI  A SG+IADA+ L+++AR+E Q H  TY E   +  + + + +L     Q+G
Sbjct: 68  VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124

Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
                     RPFG ALL  GV++K P+L+  DPSG +    A AIGS    A +  ++ 
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEL 184

Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
               MTL EAIK ++  L + M EK +A NIE+A +    + F   +KEE+E+ + ++
Sbjct: 185 CFKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241


>gi|8394063 proteasome (prosome, macropain) subunit, alpha type 2 [Rattus
           norvegicus] >gi|130851|sp|P17220|PRC3_RAT PROTEASOME
           COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C3) >gi|67726|pir||SNRTC3
           proteasome chain C3 - rat >gi|203203|gb|AAA40838.1|
           (J02897) proteasome component C3 protein [Rattus
           norvegicus] >gi|5757867|gb|AAD50623.1|AF099733_1
           (AF099733) proteasome subunit C3 [Mus musculus]
           Length = 234
           
 Score =  184 bits (462), Expect = 1e-45
 Identities = 99/233 (42%), Positives = 144/233 (61%), Gaps = 4/233 (1%)

Query: 7   QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           + GY  ++T FSP G+L Q+ YA  AV  GA +VG+K  +GVVLA EK+  S L +  S 
Sbjct: 3   ERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSV 62

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
            K+  I  HI    SG+  D RVLV+RAR  AQ + L Y EP P A +V+++  + Q +T
Sbjct: 63  HKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYT 122

Query: 127 QYGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           Q GGVRPFG +LL+ G N+ +P L+++DPSGAYFAWKA A+G          E +Y +D+
Sbjct: 123 QSGGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDL 182

Query: 186 TLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
            L++AI  AI  L ++ E + + +NIEV +    +  FR+L+  E+  +L  +
Sbjct: 183 ELEDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFRRLTPTEVRDYLAAI 233


>gb|AAF05906.1|AF148125_1 (AF148125) 20S proteasome alpha 2 subunit [Trypanosoma brucei
           brucei]
           Length = 231
           
 Score =  184 bits (462), Expect = 1e-45
 Identities = 95/226 (42%), Positives = 143/226 (63%), Gaps = 4/226 (1%)

Query: 14  ITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIFQID 73
           +T FSP GRL Q+ YA  A  +G TA+GVK  DGVV+A EK+ TS L +  +  K+F +D
Sbjct: 8   LTTFSPSGRLVQIEYATTAASKGTTALGVKATDGVVIAAEKKTTSPLADSLTLHKVFALD 67

Query: 74  DHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRP 133
           DH+    SGI  D RVLV+ AR   Q +RLTY EP P++ +V++I  L Q  TQ GGVRP
Sbjct: 68  DHVGCTYSGIGPDCRVLVDAARRACQRYRLTYHEPMPISQLVRQISFLFQEFTQSGGVRP 127

Query: 134 FGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIK 192
           FG +LL+AG + +   LY+ DPSG ++ WKA +IG G   A    E +Y ++M +++A+ 
Sbjct: 128 FGCSLLVAGADSRGNHLYQLDPSGTFWTWKATSIGKGSPDARTFLEKRYTNEMEIEDAVH 187

Query: 193 LAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
            A+  L +  + + +AEN +V    V + +F  L+ E+++ +L ++
Sbjct: 188 TALLTLKEGFDGRMTAENTQVG--RVVEGRFELLTVEQLKDYLDQI 231


>emb|CAB62817.1| (AL133435) 20S proteasome alpha 2 subunit [Leishmania major]
           Length = 231
           
 Score =  184 bits (462), Expect = 1e-45
 Identities = 95/226 (42%), Positives = 144/226 (63%), Gaps = 4/226 (1%)

Query: 14  ITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIFQID 73
           +T FSP G+L Q+ YA  A  +G TA+GVK  DGVV+A +K+  S L++  S +K+F +D
Sbjct: 8   LTTFSPSGKLVQIEYATTAAGKGTTALGVKATDGVVIAAKKKAPSTLVDASSIQKVFILD 67

Query: 74  DHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRP 133
           +H+    SG+  D RVL++ AR   Q +RL Y EP P++ +V+KI  L Q  TQ GGVRP
Sbjct: 68  EHVGCTYSGMGPDCRVLIDSARKNCQQYRLMYNEPIPISQLVRKISALYQEFTQSGGVRP 127

Query: 134 FGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIK 192
           FG +LL+AGV+ +   LY+ DPSG ++AWKA AIG+G   A A  E +Y  DM L++A+ 
Sbjct: 128 FGCSLLVAGVDANGYHLYQVDPSGTFWAWKATAIGTGSPDAKAFLEKRYTVDMELEDAVH 187

Query: 193 LAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
            A+  L +  + + ++EN +V    V   +F  LS +++  +L ++
Sbjct: 188 TALLTLKEGFDGQMTSENTQVG--RVVGNRFEVLSVDQLRDYLDQI 231


>gi|6679497 proteasome (prosome, macropain) subunit, alpha type 2 [Mus
           musculus] >gi|1709759|sp|P49722|PRC3_MOUSE PROTEASOME
           COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C3)
           >gi|897784|emb|CAA49782.1| (X70303) proteasome, 25 kDa
           subunit [Mus musculus]
           Length = 234
           
 Score =  183 bits (461), Expect = 1e-45
 Identities = 99/231 (42%), Positives = 143/231 (61%), Gaps = 4/231 (1%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GY  ++T FSP G+L Q+ YA  AV  GA +VG+K  +GVVLA EK+  S L +  S  K
Sbjct: 5   GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +  I  HI    SG+  D RVLV+RAR  AQ + L Y EP P A +V+++  + Q +TQ 
Sbjct: 65  VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124

Query: 129 GGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           GGVRPFG +LL+ G N+ +P L+++DPSGAYFAWKA A+G          E +Y +D+ L
Sbjct: 125 GGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184

Query: 188 DEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           ++AI  AI  L ++ E + + +NIEV +    +  FR+L+  E+  +L  +
Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFRRLTPTEVRDYLAAI 233


>sp|P24495|PRC3_XENLA PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C3) >gi|85841|pir||JH0421
           proteasome chain XC3 - African clawed frog
           >gi|233668|gb|AAB19485.1| (S51111) proteasome subunit
           XC3 [Xenopus laevis, Peptide, 234 aa]
           Length = 234
           
 Score =  183 bits (460), Expect = 2e-45
 Identities = 98/233 (42%), Positives = 146/233 (62%), Gaps = 4/233 (1%)

Query: 7   QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           + GY  ++T FSP G+L Q+ YA  AV  GA +VG+K  +GVVLA EK+  S L + +S 
Sbjct: 3   ERGYSFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKATNGVVLATEKKQKSILYDEQSA 62

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
            K+  I  HI    SG+  D RVLV RAR  AQ + L Y EP P A +V+++  + Q +T
Sbjct: 63  HKVEPITKHIGMVYSGMGPDYRVLVRRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYT 122

Query: 127 QYGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
           Q GGVRPFG +LL+AG ++ +P L+++DPSGAYFAWKA A+G          E +Y +D+
Sbjct: 123 QSGGVRPFGVSLLIAGWDEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDL 182

Query: 186 TLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
            L++AI  AI  L ++ E + + +NIEV +    +  F++L+  E++ +L  +
Sbjct: 183 ELEDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFKRLTPAEVKDYLAAI 233


>gi|8394072 proteasome (prosome, macropain) subunit, alpha type 5 [Rattus
           norvegicus] >gi|464457|sp|P34064|PRCZ_RAT PROTEASOME
           ZETA CHAIN (MACROPAIN ZETA CHAIN) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX ZETA CHAIN) >gi|285143|pir||JX0229
           multicatalytic endopeptidase complex (EC 3.4.99.46) zeta
           chain - rat >gi|286254|dbj|BAA01588.1| (D10756)
           proteasome subunit R-ZETA [Rattus sp.]
           Length = 241
           
 Score =  183 bits (459), Expect = 2e-45
 Identities = 104/238 (43%), Positives = 146/238 (60%), Gaps = 14/238 (5%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA E  K G+TA+G++  +GV LAVEKRITS L+EP S EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEGHKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI  A SG+IADA+ L+++AR+E Q H  TY E   +  + + + +L     Q+G
Sbjct: 68  VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124

Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
                     RPFG ALL  GV++K P+L+  DPSG +    A AIGS    A +  ++ 
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEV 184

Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           Y    TL EAIK ++  L + M EK +A NIE+A +    + F   +KEE+E+ + ++
Sbjct: 185 YHKSTTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241


>dbj|BAA96830.1| (AB026559) alpha 2 subunit of 20S proteasome [Oryza sativa]
           Length = 235
           
 Score =  182 bits (458), Expect = 3e-45
 Identities = 99/230 (43%), Positives = 146/230 (63%), Gaps = 3/230 (1%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           Y  ++T FSP G+L Q+ +A  AV  G T++G+K  +GVV+A EK++ S L++  S +KI
Sbjct: 6   YSFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKAANGVVIATEKKLPSILVDETSVQKI 65

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +  +I    SG+  D RVLV ++R +AQ +   Y E  P+  +V++   + Q  TQ G
Sbjct: 66  QSLTPNIGVVYSGMGPDFRVLVRKSRKQAQQYYRLYKETIPVTQLVRETAAVMQEFTQSG 125

Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
           GVRPFG +LL+AG +D  P+LY+ DPSG+YF+WKA A+G   + A    E +Y +DM LD
Sbjct: 126 GVRPFGVSLLIAGYDDNGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMELD 185

Query: 189 EAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           +AI  AI  L +  E + SA NIE+ +I   D++F+ LS  EI+ FL EV
Sbjct: 186 DAIHTAILTLKEGYEGQISANNIEIGIIR-SDREFKVLSPAEIKDFLEEV 234


>gb|AAC34196.1| (AF017649) alpha4 proteasome subunit [Drosophila virilis]
           Length = 247
           
 Score =  182 bits (457), Expect = 4e-45
 Identities = 105/246 (42%), Positives = 155/246 (62%), Gaps = 8/246 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRA+T+FSPDGRL QV YA+EAV++G+TAVGV+  + VVL VEK+  ++L E  +  KI
Sbjct: 5   YDRAVTIFSPDGRLLQVEYAQEAVRKGSTAVGVRGGNCVVLGVEKKSVAKLQEDRTVRKI 64

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             + DH+  A +G + DAR+L+NRA++E Q HRL   +P  L  I + I  LKQ +TQ  
Sbjct: 65  CVL-DHVVMAFAG-LTDARILINRAQVECQSHRLNVEDPVTLEYITRYIAQLKQKYTQSN 122

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           G RPFG + L+ G   +  P L++T+PSG ++ +KA A G    T    FE +YR++   
Sbjct: 123 GRRPFGISCLIGGFDADGSPYLFQTEPSGIFYEYKANATGCSAKTVREFFEKQYREEEVS 182

Query: 188 DE--AIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
            E  A+KLAI AL +  +     N+EVA++    K  + L ++ I ++L  + KE EEE 
Sbjct: 183 TERGAVKLAIRALLEVAQS-GQHNLEVAIME-NGKPLKMLDRKVILEYLDIIEKEKEEEL 240

Query: 246 VKEKEE 251
            K+K++
Sbjct: 241 EKKKQK 246


>gb|AAF60416.1| (AC006708) contains similarity to Pfam family PF00227 (Proteasome
           A-type and B-type), score=170.2, E=3.3e-47, N=1
           [Caenorhabditis elegans]
           Length = 283
           
 Score =  179 bits (450), Expect = 2e-44
 Identities = 95/247 (38%), Positives = 155/247 (62%), Gaps = 7/247 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
           YD   T+FSP+GRL+QV YA EA+    T +G+   +G+V+A E++   +L++     EK
Sbjct: 38  YDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILSSEGIVVAAERKNVHKLLDDSVMTEK 97

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           ++++ D+I+   +GI ADA +L+N  R  A  +R +YGE  P+  +V+ +C+ KQ +TQ 
Sbjct: 98  VYRLSDNISCTVAGITADANILINHLRWWAASYRNSYGEEMPVEQLVQNLCNEKQRYTQI 157

Query: 129 GGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GG RPFG +LL  G +     +LY++DPSG Y  WKA  IGS    A+ + + +Y+    
Sbjct: 158 GGKRPFGVSLLYIGWDKHYGYQLYQSDPSGNYTGWKATCIGSNHQAAVTLLKQEYKSP-N 216

Query: 187 LDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMKEVEE 243
           L+EA +LAI  L KT++ K ++E +E+AV+T +D K    +L+ +E++  + E  K+ +E
Sbjct: 217 LEEAKQLAIKVLWKTLDVKLASEKVEMAVLTRRDGKTVLEELTTKEVDALIAEHEKKEKE 276

Query: 244 EEVKEKE 250
            E  EK+
Sbjct: 277 AETAEKK 283


>sp|P40301|PRC3_DROME PROTEASOME 25 KDA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 25
           KDA SUBUNIT) >gi|486825|pir||S36116 multicatalytic
           endopeptidase complex (EC 3.4.99.46) chain PROS-Dm25 -
           fruit fly (Drosophila melanogaster)
           >gi|397850|emb|CAA49783.1| (X70304) proteasome, 25kDa
           subunit [Drosophila melanogaster]
           >gi|7299630|gb|AAF54814.1| (AE003696) Pros25 gene
           product [Drosophila melanogaster]
           Length = 234
           
 Score =  179 bits (449), Expect = 3e-44
 Identities = 96/230 (41%), Positives = 140/230 (60%), Gaps = 4/230 (1%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           Y  ++T FSP G+L Q+ YA  AV  GA +VG+   +GVV+A E +  S L E  S  ++
Sbjct: 6   YSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRV 65

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             I +HI    SG+  D R+LV +AR  AQ + LTY EP P++ +V+++  L Q +TQ G
Sbjct: 66  EMIYNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSG 125

Query: 130 GVRPFGAALLMAG-VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
           GVRPFG +LL+ G  ND+P LY++DPSGAYFAWKA A+G          E +Y +D+ LD
Sbjct: 126 GVRPFGVSLLICGWDNDRPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLELD 185

Query: 189 EAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
           +A+  AI  L +  E K +A+NIE+ +       F++L    I+ +L  +
Sbjct: 186 DAVHTAILTLKEGFEGKMTADNIEIGI--CDQNGFQRLDPASIKDYLASI 233


>gb|AAF46651.1| (AE003452) Pros29 gene product [Drosophila melanogaster]
           Length = 264
           
 Score =  179 bits (449), Expect = 3e-44
 Identities = 99/253 (39%), Positives = 156/253 (61%), Gaps = 11/253 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA EA+    T +G+  +DG++LA E R T++L++     EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I++++D++  + +GI +DA VL +  RL AQ ++ +YGE  P   +V  +CD+KQ +TQY
Sbjct: 65  IYRLNDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQY 124

Query: 129 GGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFE----DKYR 182
           GG RPFG +LL  G ++K   +LY++DPSG Y  WKA  IG+    A+++ +    DK  
Sbjct: 125 GGKRPFGVSLLYMGWDNKYGYQLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKEN 184

Query: 183 DDMTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVM 238
             +TL +A  LAI  L+ T++  K + E +E+A +   D K  +  L K ++EK + +  
Sbjct: 185 VKLTLADAKDLAIKVLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYT 244

Query: 239 KEVEEEEVKEKEE 251
           K   E E  +KE+
Sbjct: 245 KVQAEAEAAKKEK 257


>sp|P18053|PRC9_DROME PROTEASOME 29 KD SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 29
           KD SUBUNIT) >gi|103322|pir||S10318 multicatalytic
           endopeptidase complex (EC 3.4.99.46) chain PROS-29 -
           fruit fly (Drosophila melanogaster)
           >gi|8380|emb|CAA36555.1| (X52319) PROS-29 protein (AA
           1-264) [Drosophila melanogaster]
           Length = 264
           
 Score =  177 bits (444), Expect = 1e-43
 Identities = 99/253 (39%), Positives = 155/253 (61%), Gaps = 11/253 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
           YD   T+FSP+GRL+QV YA EA+    T +G+  +DG++LA E R T++L++     EK
Sbjct: 5   YDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEK 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I++ +D++  + +GI +DA VL +  RL AQ ++ +YGE  P   +V  +CD+KQ +TQY
Sbjct: 65  IYRRNDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQY 124

Query: 129 GGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFE----DKYR 182
           GG RPFG +LL  G ++K   +LY++DPSG Y  WKA  IG+    A+++ +    DK  
Sbjct: 125 GGKRPFGVSLLYMGWDNKYGYQLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKEN 184

Query: 183 DDMTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVM 238
             +TL +A  LAI  L+ T++  K + E +E+A +   D K  +  L K ++EK + +  
Sbjct: 185 VKLTLADAKDLAIKVLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYT 244

Query: 239 KEVEEEEVKEKEE 251
           K   E E  +KE+
Sbjct: 245 KVQAEAEAAKKEK 257


>gi|6321692 Proteasome subunit; Pup2p [Saccharomyces cerevisiae]
           >gi|1709764|sp|P32379|PRCZ_YEAST PROTEASOME COMPONENT
           PUP2 (MACROPAIN SUBUNIT PUP2) (PROTEINASE YSCE SUBUNIT
           PUP2) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT
           PUP2) >gi|2118148|pir||S64585 multicatalytic
           endopeptidase complex (EC 3.4.99.46) chain PUP2 - yeast
           (Saccharomyces cerevisiae) >gi|1323460|emb|CAA97282.1|
           (Z73038) ORF YGR253c [Saccharomyces cerevisiae]
           >gi|1502356|emb|CAA67615.1| (X99228) PUP2 [Saccharomyces
           cerevisiae]
           Length = 260
           
 Score =  174 bits (437), Expect = 8e-43
 Identities = 100/251 (39%), Positives = 143/251 (56%), Gaps = 12/251 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR ++ FSP+GRLFQV Y+ EA+K G+TA+G+  K+GVVL VEKR TS L+E +S EKI
Sbjct: 8   YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI  A SG+ ADAR ++  AR  A  H L Y E   +  + + +CDL     +  
Sbjct: 68  VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGA 127

Query: 130 G------VRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
                   RPFG ALL+AG   +D  +L+  +PSG ++ + A AIGSG   A A   +++
Sbjct: 128 SGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEW 187

Query: 182 RDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEV 241
              +TL EA  L +  L + ME+   EN        K   F+    E+      E++KE+
Sbjct: 188 HSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEK----TAELIKEL 243

Query: 242 EEEEVKEKEED 252
           +E+E  E  E+
Sbjct: 244 KEKEAAESPEE 254


>pdb|1G0U|D Chain D, A Gated Channel Into The Proteasome Core Particle
           >gi|11514009|pdb|1G0U|R Chain R, A Gated Channel Into
           The Proteasome Core Particle
           Length = 241
           
 Score =  174 bits (437), Expect = 8e-43
 Identities = 99/241 (41%), Positives = 140/241 (58%), Gaps = 9/241 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR ++ FSP+GRLFQV Y+ EA+K G+TA+G+  K+GVVL VEKR TS L+E +S EKI
Sbjct: 8   YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI  A SG+ ADAR ++  AR  A  H L Y E   +  + + +CDL        
Sbjct: 68  VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAM-- 125

Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
             RPFG ALL+AG   +D  +L+  +PSG ++ + A AIGSG   A A   +++   +TL
Sbjct: 126 -SRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTL 184

Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
            EA  L +  L + ME+   EN        K   F+    E+      E++KE++E+E  
Sbjct: 185 KEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEK----TAELIKELKEKEAA 240

Query: 248 E 248
           E
Sbjct: 241 E 241


>emb|CAA46111.1| (X64918) PUP2 [Saccharomyces cerevisiae]
           Length = 260
           
 Score =  173 bits (433), Expect = 2e-42
 Identities = 99/251 (39%), Positives = 143/251 (56%), Gaps = 12/251 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR ++ FSP+GRLFQV Y+ EA+K G+TA+G+  K+GVVL VEKR TS L+E +S EKI
Sbjct: 8   YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI  A SG+ ADAR ++  AR  A  H L Y E   +  + + +CDL     +  
Sbjct: 68  VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGA 127

Query: 130 G------VRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
                   RPFG ALL+AG   +D  +L+  +PSG ++ + A AIGSG   A A   +++
Sbjct: 128 SGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEW 187

Query: 182 RDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEV 241
              ++L EA  L +  L + ME+   EN        K   F+    E+      E++KE+
Sbjct: 188 HSSLSLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEK----TAELIKEL 243

Query: 242 EEEEVKEKEED 252
           +E+E  E  E+
Sbjct: 244 KEKEAAESPEE 254


>emb|CAA74025.1| (Y13691) multicatalytic endopeptidase complex, proteasome
           component, alpha subunit [Arabidopsis thaliana]
           Length = 245
           
 Score =  170 bits (427), Expect = 1e-41
 Identities = 93/233 (39%), Positives = 144/233 (60%), Gaps = 6/233 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AGYDR IT+FSP+GRLFQV YA +AVK  G T++GV+ KD V +  +K++  +L++  S 
Sbjct: 6   AGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSV 65

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             +F I  +I   ++GI ADAR LV +AR +A   R TYG   P+ ++ K I D  Q++T
Sbjct: 66  THLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYT 125

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
           Q+  +RP G   ++ GV+++  P LY+ DP+G ++  KA + G     A+   E K +++
Sbjct: 126 QHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKEN 185

Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
              T DE ++ AI AL   +++   A  IEV V+  ++ +FR L+ EEIE+ L
Sbjct: 186 PSFTFDETVQTAISALQSVLQEDFKATEIEVGVVRAENPEFRALTTEEIEEHL 238


>dbj|BAB09993.1| (AB023031) multicatalytic endopeptidase complex alpha subunit-like
           [Arabidopsis thaliana]
           Length = 246
           
 Score =  170 bits (427), Expect = 1e-41
 Identities = 93/233 (39%), Positives = 144/233 (60%), Gaps = 6/233 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AGYDR IT+FSP+GRLFQV YA +AVK  G T++GV+ KD V +  +K++  +L++  S 
Sbjct: 7   AGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             +F I  +I   ++GI ADAR LV +AR +A   R TYG   P+ ++ K I D  Q++T
Sbjct: 67  THLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYT 126

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
           Q+  +RP G   ++ GV+++  P LY+ DP+G ++  KA + G     A+   E K +++
Sbjct: 127 QHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKEN 186

Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
              T DE ++ AI AL   +++   A  IEV V+  ++ +FR L+ EEIE+ L
Sbjct: 187 PSFTFDETVQTAISALQSVLQEDFKATEIEVGVVRAENPEFRALTTEEIEEHL 239


>pdb|1G65|D Chain D, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
           Molecular Basis For Selectivity Of
           Alpha,Beta-Epoxyketone Proteasome Inhibitors
           >gi|11513430|pdb|1G65|R Chain R, Crystal Structure Of
           Epoxomicin:20s Proteasome Reveals A Molecular Basis For
           Selectivity Of Alpha,Beta-Epoxyketone Proteasome
           Inhibitors >gi|3114273|pdb|1RYP|E Chain E, Crystal
           Structure Of The 20s Proteasome From Yeast At 2.4
           Angstroms Resolution >gi|3114287|pdb|1RYP|S Chain S,
           Crystal Structure Of The 20s Proteasome From Yeast At
           2.4 Angstroms Resolution
           Length = 242
           
 Score =  169 bits (424), Expect = 3e-41
 Identities = 98/246 (39%), Positives = 140/246 (56%), Gaps = 12/246 (4%)

Query: 11  DRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIF 70
           DR ++ FSP+GRLFQV Y+ EA+K G+TA+G+  K+GVVL VEKR TS L+E +S EKI 
Sbjct: 1   DRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKIV 60

Query: 71  QIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGG 130
           +ID HI  A SG+ ADAR ++  AR  A  H L Y E   +  + + +CDL     +   
Sbjct: 61  EIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGAS 120

Query: 131 ------VRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR 182
                  RPFG ALL+AG   +D  +L+  +PSG ++ + A AIGSG   A A   +++ 
Sbjct: 121 GEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWH 180

Query: 183 DDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVE 242
             +TL EA  L +  L + ME+   EN        K   F+    E+      E++KE++
Sbjct: 181 SSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEK----TAELIKELK 236

Query: 243 EEEVKE 248
           E+E  E
Sbjct: 237 EKEAAE 242


>emb|CAB95217.1| (AL359773) proteasome subunit [Leishmania major]
           Length = 407
           
 Score =  169 bits (424), Expect = 3e-41
 Identities = 94/236 (39%), Positives = 142/236 (59%), Gaps = 18/236 (7%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE----- 64
           YD   T FSP+GRL+QV YA EA+++  T +GV  KDGVVLA EK +   L + E     
Sbjct: 127 YDSRTTTFSPEGRLYQVEYAVEAIQQAGTVIGVCTKDGVVLAGEKMVPHPLFDSENMQDK 186

Query: 65  --SYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLK 122
             S EK+++I +HI  + +G+ +DA  L+N ARL A  H+ T+ EP  +  + + +CD K
Sbjct: 187 NISGEKMYKIAEHIGCSVAGVTSDAYALLNYARLSALRHQYTFQEPIAIEDLCRILCDEK 246

Query: 123 QMHTQYGGVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
           Q++TQYGGVRP+G + L+ G +     +LY T+PSG Y AW A AIG     A ++ +  
Sbjct: 247 QLYTQYGGVRPYGVSFLLVGWDRYYGYQLYSTEPSGDYSAWSAYAIGQNDQVAHSLLKKD 306

Query: 181 YRDDMTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
           + ++MTL++ + LA+  L KTM+  K     +EVAV+       RK+    +++ L
Sbjct: 307 WHENMTLEDGMLLALRVLGKTMDTAKIDLGRVEVAVM-------RKVPASNVDQLL 355


>gb|AAC32054.1| (AF043518) 20S proteasome subunit PAA1 [Arabidopsis thaliana]
           Length = 246
           
 Score =  169 bits (423), Expect = 4e-41
 Identities = 92/233 (39%), Positives = 144/233 (61%), Gaps = 6/233 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AGYDR IT+FSP+GRLFQV YA +AVK  G T++GV+ KD V +  +K++  +L++  S 
Sbjct: 7   AGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             +F I  +I   ++GI ADAR LV +AR +A   R TYG   P+ ++ K I D  Q++T
Sbjct: 67  THLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYT 126

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
           Q+  +RP G   ++ GV+++  P LY+ DP+G ++  KA + G     A+   E++ + +
Sbjct: 127 QHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEEEMKGN 186

Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
              T DE ++ AI AL   +++   A  IEV V+  ++ +FR L+ EEIE+ L
Sbjct: 187 PSFTFDETVQTAISALQSVLQEDFKATEIEVGVVRAENPEFRALTTEEIEEHL 239


>gb|AAG28528.1|AF198387_1 (AF198387) 20S proteasome alpha 3 subunit [Trypanosoma brucei]
           Length = 286
           
 Score =  168 bits (422), Expect = 5e-41
 Identities = 98/272 (36%), Positives = 151/272 (55%), Gaps = 29/272 (10%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE----- 64
           YD   T FSP+GRL+QV YA EA+ +  T +G+    GVVL  E+     L + E     
Sbjct: 5   YDSRTTTFSPEGRLYQVEYAEEAISQAGTIIGILTTGGVVLDAERGQQHGLFDTENMEDI 64

Query: 65  --SYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLK 122
             S EK+++I +H+  + +G+ +DA  L+N ARL A  H  ++ EP     + + +CD K
Sbjct: 65  NISGEKVYKISNHLGCSVAGVTSDAYALINYARLSAARHFYSFQEPIAAEDLCRMVCDEK 124

Query: 123 QMHTQYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
           Q++TQYGGVRPFG + L AG +     +LY TD SG Y AW+A A+G     A ++ +  
Sbjct: 125 QLYTQYGGVRPFGVSFLFAGWDRHYGYQLYHTDASGNYSAWRAYAVGQNDQVAQSLLKRD 184

Query: 181 YRDDMTLDEAIKLAIFALAKTME--KPSAENIEVAVI---------------TVKDK--- 220
           ++ ++TL+E I L +  L KTM+  K + E +EVAV+                V  K   
Sbjct: 185 WKPELTLEEGIVLCLRVLGKTMDAVKLTPERLEVAVLHRVQAPLTQKLLDPYGVNPKMVP 244

Query: 221 KFRKLSKEEIEKFLGEVMKEVEEEEVKEKEED 252
            F+ L+ EE++  + E  ++ E EE +E E++
Sbjct: 245 SFKILTDEELKPHVDEANRQREAEEAEEAEKE 276


>pir||S72226 multicatalytic endopeptidase complex (EC 3.4.99.46) alpha-type
           chain Pros28.1B, testes-specific - fruit fly
           (Drosophila melanogaster) >gi|1220188|gb|AAC47281.1|
           (U46009) testes-specific proteasome subunit [Drosophila
           melanogaster]
           Length = 249
           
 Score =  168 bits (421), Expect = 6e-41
 Identities = 92/241 (38%), Positives = 147/241 (60%), Gaps = 8/241 (3%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYDRA+T++SPDG L QV YA+EAV+RG+T +G++  + +V+ VEKR    L E     K
Sbjct: 4   GYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRK 63

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +DDH+    SG+ ADAR+LV+RA++EAQ HRL + +P  +  I + I  LKQ +TQ 
Sbjct: 64  ICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQS 123

Query: 129 GGVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
            G RPFG + L+ G ++   P L++TDPSG ++ W+A   G   +  +  + +K+ D++ 
Sbjct: 124 NGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRS-SQPVRDYMEKHADEI- 181

Query: 187 LDEAIKLAIFALAKTMEKPSAEN---IEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
           L  A +  I  + +T+   S+ N   +EVAV+  + +  R +  + +      V +E+E+
Sbjct: 182 LTIADERGIKHIVRTLVSVSSLNHTQMEVAVLKYR-QPLRMIDHQVLADLERTVRREIED 240

Query: 244 E 244
           E
Sbjct: 241 E 241


>gb|AAF47215.1| (AE003464) Pros28.1B gene product [Drosophila melanogaster]
           Length = 252
           
 Score =  167 bits (419), Expect = 1e-40
 Identities = 93/241 (38%), Positives = 143/241 (58%), Gaps = 9/241 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDRA+T++SPDG L QV YA+EAV+RG+T +G++  + +V+ VEKR    L E     KI
Sbjct: 5   YDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKI 64

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +DDH+    SG+ ADAR+LV+RA++EAQ HRL + +P  +  I + I  LKQ +TQ  
Sbjct: 65  CMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSN 124

Query: 130 GVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           G RPFG + L+ G ++   P L++TDPSG ++ W+A   G          E    + +T+
Sbjct: 125 GRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTI 184

Query: 188 -DEAIKLAIFALAKTMEKPSAEN---IEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
            DEA   AI  + +T+   S+ N   +EVAV+  + +  R +  + +      V +E+E+
Sbjct: 185 ADEA--AAIKHIVRTLVSVSSLNHTQMEVAVLKYR-QPLRMIDHQVLADLERTVRREIED 241

Query: 244 E 244
           E
Sbjct: 242 E 242


>pir||T02089 proteasome chain - rice >gi|2570505|gb|AAB82138.1| (AF022735)
           proteasome component [Oryza sativa]
           Length = 261
           
 Score =  167 bits (418), Expect = 1e-40
 Identities = 91/224 (40%), Positives = 139/224 (61%), Gaps = 3/224 (1%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           Y  ++T FSP G+L Q+N+A  AV  G T++G+K  +GV +A EK++ S L++  S +KI
Sbjct: 6   YSFSLTTFSPSGKLVQINHALTAVGSGQTSLGIKAANGVFVATEKKLPSILVDETSVQKI 65

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +  ++    SG+  D RVLV ++  +AQ     Y E  P+  +V++   + Q  TQ G
Sbjct: 66  QSLTPNVGVVYSGMGPDFRVLVRKSPKQAQQCCRLYKETMPVTQLVRETAAVMQEFTQSG 125

Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
           GVRPFG +LL+AG +D  P+LY+ DPSG+YF+WKA A+G   + A    E ++ +DM LD
Sbjct: 126 GVRPFGVSLLIAGYDDNGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRHTEDMELD 185

Query: 189 EAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIE 231
           +AI   I  L +  E + SA NIE+ +I   D++F+ LS  EI+
Sbjct: 186 DAIHTGILILKEGYEGQISANNIEIGIIR-SDREFKVLSPAEIK 228


>gb|AAF55802.1| (AE003731) Pros28.1A gene product [Drosophila melanogaster]
           Length = 249
           
 Score =  166 bits (417), Expect = 2e-40
 Identities = 98/237 (41%), Positives = 137/237 (57%), Gaps = 6/237 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           Y RA+T+FSPDG L QV YA+EAV++G+TAVGV+  + VVL VEK   S + E  +  KI
Sbjct: 5   YGRALTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVRKI 64

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +D H+A A +G+ ADAR+L+NR ++E Q HRL +     L  I + +  LKQ +TQ  
Sbjct: 65  SMLDRHVALAFAGLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCN 124

Query: 130 GVRPFGAALLMAGV--NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD--M 185
           G RPFG + L+ G+  +    L+ T+PSG +  +KA A G   NT    FE  Y D    
Sbjct: 125 GRRPFGISCLIGGIDADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHEVT 184

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVE 242
           T  +AIKLA+ AL +  +  S   +EVAV+    K  + L    I + +  V  E E
Sbjct: 185 TKCDAIKLAMRALLEVTQM-SQMRLEVAVLE-NGKPMKMLDSVVISEIVKIVQNEKE 239


>gb|AAB34631.1| Doa5, PUP2=alpha-type proteasome subunit zeta homolog
           [Saccharomyces cerevisiae, Peptide, 243 aa]
           Length = 243
           
 Score =  166 bits (416), Expect = 2e-40
 Identities = 93/236 (39%), Positives = 134/236 (56%), Gaps = 8/236 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR ++ FSP+GRLFQV Y+ EA+K G+TA+G+  K+GVVL VEKR TS L+E +S EKI
Sbjct: 8   YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID HI  A SG+ ADAR ++  AR  A  H L Y E   +  + + +CDL     +  
Sbjct: 68  VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGA 127

Query: 130 G------VRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
                   RPFG ALL+AG   +D  +L+  +PSG ++ + A AIGSG   A A   +++
Sbjct: 128 SGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEW 187

Query: 182 RDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
              ++L EA  L +  L + ME+   EN        K   F+    E+  + + E+
Sbjct: 188 HSSLSLKEAELLVLKILKQVMEEKLDENNAQLTCITKQDGFKIYDNEKTAELIKEL 243


>pir||T21350 hypothetical protein F25H2.9 - Caenorhabditis elegans
           >gi|3876333|emb|CAB02097.1| (Z79754) contains similarity
           to Pfam domain: PF00227 (Proteasome A-type and B-type),
           Score=168.0, E-value=5.3e-47, N=1~cDNA EST EMBL:T00300
           comes from this gene~cDNA EST EMBL:T00299 comes from
           this gene~cDNA EST yk92h1.3 comes from this gene~cDNA
           EST y>
           Length = 248
           
 Score =  166 bits (416), Expect = 2e-40
 Identities = 96/241 (39%), Positives = 149/241 (60%), Gaps = 19/241 (7%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YDR +  FSP+GRLFQV YA EAVK G+T++G+K  +GV+LA EKR TS+L+  ++ EKI
Sbjct: 8   YDRGVNTFSPEGRLFQVEYAIEAVKLGSTSIGIKTSEGVLLAAEKRSTSKLMVNDAIEKI 67

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            ++D HI    +G+IAD+R LV RA++EAQ    TY     +  + + + +L     Q+G
Sbjct: 68  SKVDQHIGVTFAGLIADSRTLVERAQIEAQNFWFTYNRKIRVEDVTQSVANLA---LQFG 124

Query: 130 G-------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
                    RPFG A+L AGV+ +  +L+  DPSG +   KA +IG+  + A    +++Y
Sbjct: 125 DDDVKASMSRPFGVAMLFAGVDQEGAKLFHLDPSGTFIDCKAKSIGAASDGAEQNLKEQY 184

Query: 182 RDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVI--TVKDK-----KFRKLSKEEIEKF 233
            D +T+ E +K+A+  L + M EK ++ N+EV VI  TV  K     +F ++S EE+++ 
Sbjct: 185 HDALTIKEGLKMALAILKQVMEEKLNSANVEVVVIKPTVDAKGRPIGEFTRVSNEELDQV 244

Query: 234 L 234
           +
Sbjct: 245 I 245


>emb|CAB39975.1| (Y16644) PRCI [Nicotiana tabacum]
           Length = 246
           
 Score =  165 bits (414), Expect = 4e-40
 Identities = 90/232 (38%), Positives = 143/232 (60%), Gaps = 6/232 (2%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           GYDR IT+FSP+GRLFQV YA +AVK  G T++GV+ KD V +  +K++  +L++  S  
Sbjct: 8   GYDRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSVCVVTQKKVPDKLLDQTSVS 67

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
            +F I  ++   ++G+ ADAR LV +AR EA   R  YG   P+ V+ K I D  Q++TQ
Sbjct: 68  HLFPITKYLGLLATGMTADARTLVQQARNEAAEFRFKYGYEMPVDVLSKWIADKSQVYTQ 127

Query: 128 YGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD- 184
           +  +RP G   ++ G++++  P+L++ DP+G +F  KA + GS    A+   E K ++D 
Sbjct: 128 HAYMRPLGVVAMILGIDEEKGPQLFKCDPAGHFFGHKATSAGSKEQEAINFLEKKMKNDP 187

Query: 185 -MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
             + +E ++ AI AL   +++   A  IEV V+  +D  FR L+ EEI++ L
Sbjct: 188 AFSYEETVQTAISALQSVLQEDFKASEIEVGVVKKEDPIFRVLTTEEIDEHL 239


>pir||T06142 multicatalytic endopeptidase complex (EC 3.4.99.46) iota chain -
           soybean >gi|3377794|gb|AAC28135.1| (AF034572) proteasome
           IOTA subunit [Glycine max]
           Length = 246
           
 Score =  165 bits (413), Expect = 5e-40
 Identities = 90/232 (38%), Positives = 142/232 (60%), Gaps = 6/232 (2%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           GY+R IT+FSP+GRLFQV YA +AVK  G T++GV+ KD + +   K++  +L++  S  
Sbjct: 8   GYNRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSICVVTHKKVPDKLLDNTSVT 67

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
            +F I  ++   ++G+ ADAR LV +AR EA   R TYG   P+ V+ K I D  Q++TQ
Sbjct: 68  HLFPITKYLGLLATGMTADARTLVQQARNEAAEFRFTYGYEMPVDVLAKWIADKSQVYTQ 127

Query: 128 YGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD- 184
           +  +RP G   ++ G++D+  P+LY+ DP+G YF  KA + G     A+   E K ++D 
Sbjct: 128 HAYMRPLGVVAMVLGIDDEYGPQLYKCDPAGHYFGHKATSAGLKDQEAINFLEKKMKNDP 187

Query: 185 -MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
             T +E ++ AI AL   +++   A  IEV V+   + +FR L+ +EI++ L
Sbjct: 188 SFTYEETVQTAISALQSVLQEDFKATEIEVGVVRKDNPEFRVLTTDEIDEHL 239


>gi|6323547 proteasome component Y7; Pre8p [Saccharomyces cerevisiae]
           >gi|130880|sp|P23639|PRC3_YEAST PROTEASOME COMPONENT Y7
           (MACROPAIN SUBUNIT Y7) (PROTEINASE YSCE SUBUNIT 7)
           (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT Y7)
           >gi|67727|pir||SNBYY7 multicatalytic endopeptidase
           complex (EC 3.4.99.46) chain Y7 - yeast (Saccharomyces
           cerevisiae) >gi|11513413|pdb|1G65|A Chain A, Crystal
           Structure Of Epoxomicin:20s Proteasome Reveals A
           Molecular Basis For Selectivity Of
           Alpha,Beta-Epoxyketone Proteasome Inhibitors
           >gi|11513427|pdb|1G65|O Chain O, Crystal Structure Of
           Epoxomicin:20s Proteasome Reveals A Molecular Basis For
           Selectivity Of Alpha,Beta-Epoxyketone Proteasome
           Inhibitors >gi|11513992|pdb|1G0U|A Chain A, A Gated
           Channel Into The Proteasome Core Particle
           >gi|11514006|pdb|1G0U|O Chain O, A Gated Channel Into
           The Proteasome Core Particle >gi|3114270|pdb|1RYP|B
           Chain B, Crystal Structure Of The 20s Proteasome From
           Yeast At 2.4 Angstroms Resolution >gi|3114284|pdb|1RYP|P
           Chain P, Crystal Structure Of The 20s Proteasome From
           Yeast At 2.4 Angstroms Resolution
           >gi|506482|emb|CAA40055.1| (X56731) proteasome Y7
           subunit [Saccharomyces cerevisiae]
           >gi|575711|emb|CAA86646.1| (Z46660) proteasome component
           Y gene, len: 250, CAI:0.15, PRCX_YEAST P23639
           [Saccharomyces cerevisiae]
           Length = 250
           
 Score =  164 bits (410), Expect = 1e-39
 Identities = 93/239 (38%), Positives = 145/239 (59%), Gaps = 18/239 (7%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           Y  ++T FSP G+L Q++YA  AVK+G T++G+K  +GVV+A EK+ +S L   E+  K+
Sbjct: 5   YSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKV 64

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQI-HRLTYGEPAPLAVIVKKICDLKQMHTQY 128
             +   I A  SG+  D RVLV+++R  A   ++  YGE  P  ++V ++  + Q  TQ 
Sbjct: 65  SLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQS 124

Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GGVRPFG +LL+AG ++     LY+ DPSG+YF WKA AIG G   A    E ++ D++ 
Sbjct: 125 GGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELE 184

Query: 187 LDEAIKLAIFALAKTME-KPSAENIEVAVI--------------TVKDKKFRKLSKEEI 230
           L++AI +A+  L +++E + + + IE+A+I              T K  +FRKL+ +EI
Sbjct: 185 LEDAIHIALLTLKESVEGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQEI 243


>gi|6324938 proteasome component YC1 (protease yscE subunit 1); Pre10p
           [Saccharomyces cerevisiae]
           >gi|130847|sp|P21242|PRC8_YEAST PROTEASOME COMPONENT C1
           (MACROPAIN SUBUNIT C1) (PROTEINASE YSCE SUBUNIT 1)
           (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C1)
           >gi|67729|pir||SNBYC1 multicatalytic endopeptidase
           complex (EC 3.4.99.46) chain YC1 - yeast (Saccharomyces
           cerevisiae) >gi|173204|gb|AAA35227.1| (M55436) yeast
           proteasome subunit YC1 [Saccharomyces cerevisiae]
           >gi|1420786|emb|CAA99691.1| (Z75270) ORF YOR362c
           [Saccharomyces cerevisiae]
           Length = 288
           
 Score =  163 bits (409), Expect = 2e-39
 Identities = 95/254 (37%), Positives = 138/254 (53%), Gaps = 4/254 (1%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + +VFSPDGR FQV YA +AV+ G T++G+KC DGVV AVEK ITS+L+ P+   K
Sbjct: 7   GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +D HI    SG+I D R LVNR R EA   +  Y  P P+     ++    Q HT Y
Sbjct: 67  IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126

Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DKYRDD 184
             VRPFG + +  GV+ +   LY  +PSG+Y+ +K  A G GR +A A  E   D + + 
Sbjct: 127 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 186

Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
           ++  EA+K A   +    E    ++ E+ +      +   L K      L E +   ++E
Sbjct: 187 LSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQKE 246

Query: 245 EVKEKEEDYSELDS 258
              + +ED  + D+
Sbjct: 247 INGDDDEDEDDSDN 260


>gb|AAC32055.1| (AF043519) 20S proteasome subunit PAA2 [Arabidopsis thaliana]
           >gi|4006819|gb|AAC95161.1| (AC005970) 20S proteasome
           subunit (PAA2) [Arabidopsis thaliana]
           Length = 246
           
 Score =  162 bits (407), Expect = 3e-39
 Identities = 88/233 (37%), Positives = 139/233 (58%), Gaps = 6/233 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AGYDR IT+FSP+GRLFQV YA +AVK  G T++GV+ KD V +  +K++  +L++  S 
Sbjct: 7   AGYDRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             +F +  ++   ++G+ AD+R LV +AR EA   R  YG   P  ++ K I D  Q++T
Sbjct: 67  SHLFPVTKYLGLLATGMTADSRSLVQQARNEAAEFRFQYGYEMPADILAKWIADKSQVYT 126

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
           Q+  +RP G   ++ G++++  P LY+ DP+G ++  KA + G     A+   E K +++
Sbjct: 127 QHAYMRPLGVVAMVLGIDEERGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKEN 186

Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
              T DE ++ AI AL   +++   A  IEV V+   D  FR L  EEI++ L
Sbjct: 187 PAFTYDETVQTAISALQSVLQEDFKATEIEVGVVRADDPLFRSLRTEEIDEHL 239


>sp|Q27488|PRC3_CAEEL PROBABLE PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT C3)
           (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C3)
           >gi|7498128|pir||T20304 hypothetical protein D1054.2 -
           Caenorhabditis elegans >gi|3875311|emb|CAA98441.1|
           (Z74030) Similarity to Xenopus proteasome component C3
           (SW:PRC3_XENLA), contains similarity to Pfam domain:
           PF00227 (Proteasome A-type and B-type), Score=178.5,
           E-value=3.4e-50, N=1~cDNA EST yk511b9.3 comes from this
           gene~cDNA EST yk541h3.3 comes from >
           Length = 231
           
 Score =  161 bits (404), Expect = 6e-39
 Identities = 94/230 (40%), Positives = 135/230 (57%), Gaps = 9/230 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           Y  ++T FSP G+L Q+ YA  AVK G  +VG++ KDGVVLA E  + S L + +   K+
Sbjct: 5   YGFSLTTFSPSGKLMQIEYALNAVKNGQPSVGLRAKDGVVLATEN-VGSVLTDDQP--KV 61

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            QI  HI    SG+  D R+LV +AR  A  + + YGE  P   +V  I  + Q +TQ G
Sbjct: 62  EQISKHIGCVYSGMGPDFRILVKKARKIAMEYEMMYGEEMPTIQLVTDIAAVMQEYTQSG 121

Query: 130 GVRPFGAALLMAGVN---DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           GVRPFGA+LL+AG +    +P L++ DPSGAYFAWKA A+G     A    E ++ + + 
Sbjct: 122 GVRPFGASLLIAGWDKNPGRPLLFQCDPSGAYFAWKATALGKNDVNAKTFLEKRFSEALE 181

Query: 187 LDEAIKLAIFALAKTMEKPSAE-NIEVAVITVKDKKFRKLSKEEIEKFLG 235
           LD+ I  A+  L ++ +    E N+EVAV       F +L+K+++   LG
Sbjct: 182 LDDGIHTALLTLRESFDVGMNENNVEVAV--CNSTGFHRLTKQQVHDHLG 229


>sp|Q27563|PRC8_DICDI PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C8)
           >gi|1408304|gb|AAB03671.1| (U61988) PrtD [Dictyostelium
           discoideum]
           Length = 248
           
 Score =  161 bits (403), Expect = 8e-39
 Identities = 77/186 (41%), Positives = 119/186 (63%), Gaps = 1/186 (0%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           +GYD  ++ +SPDG+LFQV+YA +AV+   T V +K KDGVVL VEK + S+++   S  
Sbjct: 6   SGYDLYVSTYSPDGKLFQVDYANKAVENSGTLVAIKAKDGVVLGVEKLVPSKMLCSGSNR 65

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           ++  ID H+  A +G +ADAR L+ RAR EA+ ++ TYG+P P+ V+ ++I     MHT 
Sbjct: 66  RVHHIDTHVGVAIAGFLADARQLITRARSEAKNYKSTYGQPIPIKVLSQRIASYNHMHTL 125

Query: 128 YGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           YG VRPFG ++ + G++   P+L+  +PSG+   +   ++G G+  A    E+    +MT
Sbjct: 126 YGSVRPFGCSIAITGIDQYGPQLFLVEPSGSCVGYFGASLGKGKQAAKNELEEIRFSEMT 185

Query: 187 LDEAIK 192
             EAIK
Sbjct: 186 CREAIK 191


>pdb|1G65|F Chain F, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
           Molecular Basis For Selectivity Of
           Alpha,Beta-Epoxyketone Proteasome Inhibitors
           >gi|11513432|pdb|1G65|T Chain T, Crystal Structure Of
           Epoxomicin:20s Proteasome Reveals A Molecular Basis For
           Selectivity Of Alpha,Beta-Epoxyketone Proteasome
           Inhibitors >gi|3114275|pdb|1RYP|G Chain G, Crystal
           Structure Of The 20s Proteasome From Yeast At 2.4
           Angstroms Resolution >gi|3114289|pdb|1RYP|U Chain U,
           Crystal Structure Of The 20s Proteasome From Yeast At
           2.4 Angstroms Resolution
           Length = 244
           
 Score =  161 bits (402), Expect = 1e-38
 Identities = 96/247 (38%), Positives = 139/247 (55%), Gaps = 14/247 (5%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + +VFSPDGR FQV YA +AV+ G T++G+KC DGVV AVEK ITS+L+ P+   K
Sbjct: 3   GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 62

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +D HI    SG+I D R LVNR R EA   +  Y  P P+     ++    Q HT Y
Sbjct: 63  IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 122

Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DKYRDD 184
             VRPFG + +  GV+ +   LY  +PSG+Y+ +K  A G GR +A A  E   D + + 
Sbjct: 123 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 182

Query: 185 MTLDEAIKLA--IFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFL-GEVMKEV 241
           ++  EA+K A  I  LA    K     +E++  ++ +          + KF+ G++++E 
Sbjct: 183 LSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSE-------TNGLHKFVKGDLLQEA 235

Query: 242 EEEEVKE 248
            +   KE
Sbjct: 236 IDFAQKE 242


>pdb|1G0U|F Chain F, A Gated Channel Into The Proteasome Core Particle
           >gi|11514011|pdb|1G0U|T Chain T, A Gated Channel Into
           The Proteasome Core Particle
           Length = 248
           
 Score =  161 bits (402), Expect = 1e-38
 Identities = 96/247 (38%), Positives = 139/247 (55%), Gaps = 14/247 (5%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + +VFSPDGR FQV YA +AV+ G T++G+KC DGVV AVEK ITS+L+ P+   K
Sbjct: 7   GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +D HI    SG+I D R LVNR R EA   +  Y  P P+     ++    Q HT Y
Sbjct: 67  IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126

Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DKYRDD 184
             VRPFG + +  GV+ +   LY  +PSG+Y+ +K  A G GR +A A  E   D + + 
Sbjct: 127 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 186

Query: 185 MTLDEAIKLA--IFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFL-GEVMKEV 241
           ++  EA+K A  I  LA    K     +E++  ++ +          + KF+ G++++E 
Sbjct: 187 LSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSE-------TNGLHKFVKGDLLQEA 239

Query: 242 EEEEVKE 248
            +   KE
Sbjct: 240 IDFAQKE 246


>dbj|BAA96829.1| (AB026558) alpha 1 subunit of 20S proteasome [Oryza sativa]
           Length = 246
           
 Score =  160 bits (401), Expect = 1e-38
 Identities = 89/233 (38%), Positives = 142/233 (60%), Gaps = 6/233 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AGYDR IT+FSP+GRL+QV YA +AVK  G T++GV+ KD V +  +K++  +L++  S 
Sbjct: 7   AGYDRHITIFSPEGRLYQVEYAFKAVKSAGVTSIGVRGKDSVCVVTQKKVPDKLLDHTSV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             +F I  +I   ++G+ ADAR LV +AR EA   R  +G   P+ V+ K I D  Q++T
Sbjct: 67  THLFPITKYIGLLATGLTADARSLVYQARNEAAEFRFKWGYEMPVDVLAKWIADKAQVYT 126

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
           Q+  +RP G   ++ G +++   +L++ DP+G +F  KA + G     A+   E K +DD
Sbjct: 127 QHAYMRPLGVVAMVLGYDEEKNAQLFKCDPAGHFFGHKATSAGLKEQEAINFLEKKMKDD 186

Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
              + +E +++AI AL   +++   A  IEV V+   D+ FR L+ EEI++ L
Sbjct: 187 PQFSYEETVQIAISALQSVLQEDFKATEIEVGVVRKDDRVFRALTTEEIDQHL 239


>gb|AAF59183.1| (AE003839) Prosalpha1 gene product [alt 1] [Drosophila
           melanogaster] >gi|7304147|gb|AAF59184.1| (AE003839)
           Prosalpha1 gene product [alt 2] [Drosophila
           melanogaster]
           Length = 244
           
 Score =  160 bits (400), Expect = 2e-38
 Identities = 87/239 (36%), Positives = 149/239 (61%), Gaps = 8/239 (3%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAV-KRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AG+DR IT+FSP+GRL+QV YA +A+ +   T V +K  D  V+A +K++T + I PE+ 
Sbjct: 7   AGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             +F+I   I  A +G IAD+R  V +AR EA   R  YG   P+ V+ ++I D+ Q++T
Sbjct: 67  THLFRITKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYT 126

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
           Q   +RP G ++++   +++  P +Y+TDP+G +  +KA ++G+    A +  E KY+ +
Sbjct: 127 QNAEMRPLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPN 186

Query: 185 MTLDEAIKLAIFALAKTME---KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
           ++ ++AI+LAI  L+  +    KP+   IE+ V++  D  FR L + EIE+ L ++ ++
Sbjct: 187 LSEEKAIQLAISCLSSVLAIDFKPN--GIEIGVVSKSDPTFRILDEREIEEHLTKIAEK 243


>pir||S72225 multicatalytic endopeptidase complex (EC 3.4.99.46) alpha-type
           chain Pros28.1A, testes-specific - fruit fly
           (Drosophila melanogaster) >gi|1220186|gb|AAC47280.1|
           (U46008) testes-specific proteasome subunit alpha-type
           [Drosophila melanogaster]
           Length = 249
           
 Score =  159 bits (399), Expect = 2e-38
 Identities = 95/237 (40%), Positives = 134/237 (56%), Gaps = 6/237 (2%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           Y RA+T+FSPDG L QV Y +EAV++G+TAVGV+  + VVL VEK   S + E  +  KI
Sbjct: 5   YGRALTIFSPDGHLLQVEYGQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVRKI 64

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             +D H+A A +G+ ADAR+L+NR ++E Q HRL +     L  I + +  LKQ +TQ  
Sbjct: 65  SMLDRHVALAFAGLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQVN 124

Query: 130 GVRPFGAALLMAGV--NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD--M 185
           G   FG + L+ G+  +    L+ T+PSG +  +KA A G   NT    FE  Y D    
Sbjct: 125 GRPSFGISCLIGGIDADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHEVT 184

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVE 242
           T  +AIKLA+ AL +  +  S   +EVAV+    K  + L    I + +  V  E E
Sbjct: 185 TKCDAIKLAMRALLEVTQM-SQMRLEVAVLE-NGKPMKMLDSVVISEIVKIVQNEKE 239


>gi|8394076 proteasome (prosome, macropain) subunit, alpha type 6 [Rattus
           norvegicus] >gi|464447|sp|P34062|PRCI_HUMAN PROTEASOME
           IOTA CHAIN (MACROPAIN IOTA CHAIN) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX IOTA CHAIN) (27 KDA PROSOMAL
           PROTEIN) (PROS-27) (P27K) >gi|285141|pir||JX0230
           multicatalytic endopeptidase complex (EC 3.4.99.46) iota
           chain - rat >gi|418785|pir||S30274 multicatalytic
           endopeptidase complex (EC 3.4.99.46) iota chain - human
           >gi|35682|emb|CAA42052.1| (X59417) prosomal P27K protein
           [Homo sapiens] >gi|286250|dbj|BAA01587.1| (D10755)
           proteasome subunit R-IOTA [Rattus sp.]
           >gi|446773|prf||1912298A prosomal RNA-binding protein
           p27K [Homo sapiens]
           Length = 246
           
 Score =  159 bits (398), Expect = 3e-38
 Identities = 85/235 (36%), Positives = 146/235 (61%), Gaps = 10/235 (4%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGA-TAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AG+DR IT+FSP+GRL+QV YA +A+ +G  T+V V+ KD  V+  +K++  +L++  + 
Sbjct: 7   AGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             +F+I ++I    +G+ AD+R  V RAR EA   +  YG   P+ ++ K+I D+ Q++T
Sbjct: 67  THLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYT 126

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD- 183
           Q   +RP G  +++ G++++  P++Y+ DP+G Y  +KA A G  +  + +  E K +  
Sbjct: 127 QNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKK 186

Query: 184 -DMTLDEAIKLAIFALAKTME---KPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
            D T ++ ++ AI  L+  +    KPS   IEV V+TV++ KFR L++ EI+  L
Sbjct: 187 FDWTFEQTVETAITCLSTVLSIDFKPS--EIEVGVVTVENPKFRILTEAEIDAHL 239


>sp|P90513|PRC8_ACACA PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C8)
           >gi|1809142|gb|AAB41645.1| (U85398) multicatalytic
           endopeptidase subunit C8 [Acanthamoeba castellanii]
           Length = 252
           
 Score =  159 bits (398), Expect = 3e-38
 Identities = 93/250 (37%), Positives = 144/250 (57%), Gaps = 9/250 (3%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + T FSPDGR+FQV YA +AV    TA+G++ KDGVVLAVEK + S+++ P +  +
Sbjct: 5   GYDLSSTTFSPDGRVFQVEYAAKAVDNSGTALGLRVKDGVVLAVEKLLVSKMLVPNTNRR 64

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +D H   A SG++AD R LV+R R EA  +R  YG      V+ +++ +  Q+++ Y
Sbjct: 65  IHTVDRHCGLAMSGLVADGRQLVSRGRAEATSYREFYGTDISGKVLNERLSNFVQLYSLY 124

Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
           G VRPFG ++++  V+ + P+LY  +PSG  + +  VAIG G   A    E     +MT 
Sbjct: 125 GSVRPFGTSVILGCVDKNGPQLYMIEPSGISWGYFGVAIGKGARAAKTEIEKLKLSEMTA 184

Query: 188 DEAIKLAIFALAKTME--KPSAENIEVAVITVKDKKFRKLSK----EEIEKFLGEVMKEV 241
            EAIK A   +    +  K  A  +E++ +  +     K       EE EK+  + ++  
Sbjct: 185 REAIKEAAKIIYSVHDDAKDKAFELELSWVCEETGNLHKFVPKDLLEEAEKYAKQALE-- 242

Query: 242 EEEEVKEKEE 251
           EEE++ E+E+
Sbjct: 243 EEEDMSEEED 252


>gi|6755198 proteasome (prosome, macropain) subunit, alpha type 6 [Mus
           musculus] >gi|9910829|sp|Q9QUM9|PRCI_MOUSE PROTEASOME
           IOTA CHAIN (MACROPAIN IOTA CHAIN) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX IOTA CHAIN)
           >gi|5757651|gb|AAD50532.1|AF060087_1 (AF060087)
           proteasome subunit iota [Mus musculus]
           >gi|6649571|gb|AAF21459.1|U60288_1 (U60288) proteasome
           subunit iota [Mus musculus]
           Length = 246
           
 Score =  158 bits (396), Expect = 5e-38
 Identities = 85/235 (36%), Positives = 145/235 (61%), Gaps = 10/235 (4%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGA-TAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AG+DR IT+FSP+GRL+QV YA +A+ +G  T+V V+ KD  V+  +K++  +L++  + 
Sbjct: 7   AGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             +F+I + I    +G+ AD+R  V RAR EA   +  YG   P+ ++ K+I D+ Q++T
Sbjct: 67  THLFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYT 126

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD- 183
           Q   +RP G  +++ G++++  P++Y+ DP+G Y  +KA A G  +  + +  E K +  
Sbjct: 127 QNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKK 186

Query: 184 -DMTLDEAIKLAIFALAKTME---KPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
            D T ++ ++ AI  L+  +    KPS   IEV V+TV++ KFR L++ EI+  L
Sbjct: 187 FDWTFEQTVETAITCLSTVLSIDFKPS--EIEVGVVTVENPKFRILTEAEIDAHL 239


>gb|AAD33944.1|AF144749_1 (AF144749) 20S proteasome subunit alpha1 [Drosophila melanogaster]
           Length = 244
           
 Score =  158 bits (395), Expect = 7e-38
 Identities = 86/239 (35%), Positives = 148/239 (60%), Gaps = 8/239 (3%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAV-KRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AG+DR IT+FSP+GRL+QV YA +A+ +   T V +K  D  V+A +K++T + I PE+ 
Sbjct: 7   AGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             +F+I   I  A +G IAD+R  V + R EA   R  YG   P+ V+ ++I D+ Q++T
Sbjct: 67  THLFRITKDIGCAMTGRIADSRSQVQKGRYEAANFRYKYGYEMPVDVLCRRIADITQVYT 126

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
           Q   +RP G ++++   +++  P +Y+TDP+G +  +KA ++G+    A +  E KY+ +
Sbjct: 127 QNAEMRPLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPN 186

Query: 185 MTLDEAIKLAIFALAKTME---KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
           ++ ++AI+LAI  L+  +    KP+   IE+ V++  D  FR L + EIE+ L ++ ++
Sbjct: 187 LSEEKAIQLAISCLSSVLAIDFKPN--GIEIGVVSKSDPTFRILDEREIEEHLTKIAEK 243


>gi|8394066 proteasome (prosome, macropain) subunit, alpha type 3 [Rattus
           norvegicus] >gi|130860|sp|P18422|PRC8_RAT PROTEASOME
           COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C8) (PROTEASOME SUBUNIT K)
           >gi|67731|pir||SNRTC8 multicatalytic endopeptidase
           complex (EC 3.4.99.46) chain C8 - rat
           >gi|56639|emb|CAA39457.1| (X55985) multicatalytic
           proteinase subunit K [Rattus rattus]
           >gi|203207|gb|AAA40840.1| (M58593) proteasome component
           C8 [Rattus norvegicus] >gi|220879|dbj|BAA14302.1|
           (D90258) proteasome subunit C8 [Rattus rattus]
           Length = 255
           
 Score =  156 bits (390), Expect = 3e-37
 Identities = 88/245 (35%), Positives = 134/245 (53%), Gaps = 8/245 (3%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + + FSPDGR+FQV YA +AV+  +TA+G++CKDGVV  VEK + S+L E  S ++
Sbjct: 7   GYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +F +D H+  A +G++ADAR L + AR EA   R  +G   PL  +  ++      +T Y
Sbjct: 67  LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126

Query: 129 GGVRPFGAALLMA--GVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
             VRPFG + ++    VND  +LY  DPSG  + +   AIG  R  A    E     +MT
Sbjct: 127 SAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMT 186

Query: 187 LDEAIK--LAIFALAKTMEKPSAENIEVAVITVKDKKFRKL----SKEEIEKFLGEVMKE 240
             + +K    I  +     K  A  +E++ +    K   ++     +EE EK+  E +KE
Sbjct: 187 CRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDVREEAEKYAKESLKE 246

Query: 241 VEEEE 245
            +E +
Sbjct: 247 EDESD 251


>gi|4506183 proteasome (prosome, macropain) subunit, alpha type, 3 [Homo
           sapiens] >gi|11434353|ref|XP_007345.1| proteasome
           (prosome, macropain) subunit, alpha type, 3 [Homo
           sapiens] >gi|130859|sp|P25788|PRC8_HUMAN PROTEASOME
           COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C8) >gi|67730|pir||SNHUC8
           multicatalytic endopeptidase complex (EC 3.4.99.46)
           chain C8 - human >gi|220028|dbj|BAA00659.1| (D00762)
           proteasome subunit C8 [Homo sapiens]
           Length = 255
           
 Score =  155 bits (387), Expect = 6e-37
 Identities = 88/245 (35%), Positives = 134/245 (53%), Gaps = 8/245 (3%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + + FSPDGR+FQV YA +AV+  +TA+G++CKDGVV  VEK + S+L E  S ++
Sbjct: 7   GYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +F +D H+  A +G++ADAR L + AR EA   R  +G   PL  +  ++      +T Y
Sbjct: 67  LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126

Query: 129 GGVRPFGAALLMA--GVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
             VRPFG + ++    VND  +LY  DPSG  + +   AIG  R  A    E     +MT
Sbjct: 127 SAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMT 186

Query: 187 LDEAIK--LAIFALAKTMEKPSAENIEVA----VITVKDKKFRKLSKEEIEKFLGEVMKE 240
             + +K    I  +     K  A  +E++    +   + +   K  +EE EK+  E +KE
Sbjct: 187 CRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKE 246

Query: 241 VEEEE 245
            +E +
Sbjct: 247 EDESD 251


>emb|CAA62960.1| (X91847) proteasome subunit C9-like protein [Sus scrofa]
           Length = 226
           
 Score =  154 bits (386), Expect = 8e-37
 Identities = 90/226 (39%), Positives = 143/226 (62%), Gaps = 10/226 (4%)

Query: 41  GVKCKDGVVLAVEKRITSRLIEPESY-EKIFQIDDHIAAASSGIIADARVLVNRARLEAQ 99
           G+   DGV+LA E+R   +L++   + EKI+++++ +A + +GI +DA VL N  RL AQ
Sbjct: 1   GILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQ 60

Query: 100 IHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKP---ELYETDPSG 156
            + L Y EP P   +V  +CD+KQ +TQ+GG RPFG +LL  G  DK    +LY++DPSG
Sbjct: 61  RYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGW-DKHYGFQLYQSDPSG 119

Query: 157 AYFAWKAVAIGSGRNTAMAIFEDKYRD-DMTLDEAIKLAIFALAKTME--KPSAENIEVA 213
            Y  WKA  IG+    A+++ +  Y++ +MTL  A+ LAI  L KTM+  K SAE +E+A
Sbjct: 120 NYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIA 179

Query: 214 VITVKDKK--FRKLSKEEIEKFLGEVMKEVEEEEVKEKEEDYSELD 257
            +T ++ K   R L ++E+E+ + +  +E  + E ++KE++  E D
Sbjct: 180 TLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKD 225


>gi|6755194 proteasome (prosome, macropain) subunit, alpha type 3 [Mus
           musculus] >gi|3914438|sp|O70435|PRC8_MOUSE PROTEASOME
           COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C8) (PROTEASOME SUBUNIT K)
           >gi|3037091|gb|AAC12943.1| (AF055983) proteasome
           alpha7/C8 subunit [Mus musculus]
           >gi|5757655|gb|AAD50534.1|AF060089_1 (AF060089)
           proteasome subunit C8 [Mus musculus]
           Length = 255
           
 Score =  154 bits (386), Expect = 8e-37
 Identities = 87/245 (35%), Positives = 133/245 (53%), Gaps = 8/245 (3%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + + FSPDGR+FQV YA +AV+  +TA+G++CKDGVV  VEK + S+L E  S ++
Sbjct: 7   GYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +F +D H+  A +G++ADAR L + AR EA   R  +G   PL  +  ++      +T Y
Sbjct: 67  LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126

Query: 129 GGVRPFGAALLMA--GVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
             VRPFG + ++     ND  +LY  DPSG  + +   AIG  R  A    E     +MT
Sbjct: 127 SAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMT 186

Query: 187 LDEAIK--LAIFALAKTMEKPSAENIEVAVITVKDKKFRKL----SKEEIEKFLGEVMKE 240
             + +K    I  +     K  A  +E++ +    K   ++     +EE EK+  E +KE
Sbjct: 187 CRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDIREEAEKYAKESLKE 246

Query: 241 VEEEE 245
            +E +
Sbjct: 247 EDESD 251


>sp|P34066|PRC2_ARATH PROTEASOME, 30 KD SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 30
           KD SUBUNIT) >gi|541889|pir||S39900 multicatalytic
           endopeptidase complex 30K chain homolog - Arabidopsis
           thaliana >gi|166830|gb|AAA16326.1| (M98495) proteasome
           [Arabidopsis thaliana] >gi|10177282|dbj|BAB10635.1|
           (AB007647) 20S proteasome subunit PAF1 [Arabidopsis
           thaliana]
           Length = 278
           
 Score =  152 bits (379), Expect = 5e-36
 Identities = 95/254 (37%), Positives = 144/254 (56%), Gaps = 9/254 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YD  +T +SP GRLFQV YA EAVK+G+ A+G++ +  VVLA   +  S L   +   KI
Sbjct: 6   YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RKI 63

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
           F++DDHI  A +G+ AD RVL    R E+  H  TY  P P+  +V  + D  Q+ TQ  
Sbjct: 64  FKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRS 123

Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DMT 186
             RP+G  LL+ G+++    LY   PSG YF ++A AIGS    A    E ++    D +
Sbjct: 124 WKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSS 183

Query: 187 LDEAIKLAIFALAKTMEKPSAEN--IEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
            ++ IK AI A+ +T++  + ++    VA++ V D+ F  L +E I+K + +  ++V EE
Sbjct: 184 REDLIKDAILAVRETLQGETLKSSLCTVAILGV-DEPFHFLDQEAIQKVI-DTFEKVPEE 241

Query: 245 EVKEKEEDYSELDS 258
           E  E E    E ++
Sbjct: 242 EEGEGEAGEGEAEA 255


>gb|AAC32062.1| (AF043526) 20S proteasome subunit PAF1 [Arabidopsis thaliana]
           Length = 278
           
 Score =  152 bits (379), Expect = 5e-36
 Identities = 95/254 (37%), Positives = 144/254 (56%), Gaps = 9/254 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YD  +T +SP GRLFQV YA EAVK+G+ A+G++ +  VVLA   +  S L   +   KI
Sbjct: 6   YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RKI 63

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
           F++DDHI  A +G+ AD RVL    R E+  H  TY  P P+  +V  + D  Q+ TQ  
Sbjct: 64  FKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRS 123

Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DMT 186
             RP+G  LL+ G+++    LY   PSG YF ++A AIGS    A    E ++    D +
Sbjct: 124 WKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSS 183

Query: 187 LDEAIKLAIFALAKTMEKPSAEN--IEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
            ++ IK AI A+ +T++  + ++    VA++ V D+ F  L +E I+K + +  ++V EE
Sbjct: 184 REDLIKDAILAVRETLQGETLKSSLCTVAILGV-DEPFHFLDQEAIQKVI-DTFEKVPEE 241

Query: 245 EVKEKEEDYSELDS 258
           E  E E    E ++
Sbjct: 242 EEGEGEAGEGEAEA 255


>gb|AAC32063.1| (AF043527) 20S proteasome subunit PAF2 [Arabidopsis thaliana]
           >gi|10092412|gb|AAG12817.1|AC079677_6 (AC079677) 20S
           proteasome subunit PAF2; 11103-9423 [Arabidopsis
           thaliana]
           Length = 277
           
 Score =  152 bits (379), Expect = 5e-36
 Identities = 93/243 (38%), Positives = 136/243 (55%), Gaps = 12/243 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YD  +T +SP GRLFQV YA EAVK+G+ A+G++ +  VVLA   +  S L   +   KI
Sbjct: 6   YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RKI 63

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
           F++DDHI  A +G+ AD RVL    R E+  H  TY  P P+  +V  + D  Q+ TQ  
Sbjct: 64  FKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRS 123

Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDMT 186
             RP+G  LL+ G+++    LY   PSG YF ++A AIGS    A    E K+    + +
Sbjct: 124 WKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERKFESFQESS 183

Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVK----DKKFRKLSKEEIEKFLGEVMKEVE 242
            ++ IK AI A+ +T++    E ++ ++ TV     D+ F  L +E I+K +    K  E
Sbjct: 184 KEDLIKDAIMAIRETLQ---GETLKSSLCTVSVLGVDEPFHFLDQESIQKVIDTFEKVPE 240

Query: 243 EEE 245
           EEE
Sbjct: 241 EEE 243


>pir||T19320 hypothetical protein C15H11.7 - Caenorhabditis elegans
           >gi|3874351|emb|CAB02738.1| (Z81035) Similarity to Human
           proteasome iota chain (SW:P34062), contains similarity
           to Pfam domain: PF00227 (Proteasome A-type and B-type),
           Score=132.6, E-value=2.4e-36, N=1~cDNA EST EMBL:T00439
           comes from this gene~cDNA EST yk242c6.5 comes from this
           g>
           Length = 246
           
 Score =  151 bits (378), Expect = 7e-36
 Identities = 86/236 (36%), Positives = 138/236 (58%), Gaps = 6/236 (2%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AG+DR IT+FSP+GR++QV YA +A+     TAV VK  D  V+AV+KR+   LI  ++ 
Sbjct: 7   AGFDRHITIFSPEGRVYQVEYAFKAINSTNLTAVAVKGADAAVIAVQKRVPDSLIVADTV 66

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             ++QI   +   + G+I DA+  + RA+ EA   +   G   P  ++ KK+ DL Q +T
Sbjct: 67  TSVYQISQSVGCCAIGMIPDAKFQIKRAQGEAASWKYKNGYDMPCELLAKKMADLNQYYT 126

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY--R 182
           Q   +R  G ALL    +D+  PE+Y  DP+G Y   K V++G  +  A +  E K   +
Sbjct: 127 QNAEMRSLGCALLFISYDDEKGPEVYRVDPAGYYRGMKGVSVGVKQLPATSFLEKKIKKK 186

Query: 183 DDMTLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
            ++T  EAI+LAI AL  ++     ++++EV V+T  + KF KL+ +++E  L ++
Sbjct: 187 SELTSTEAIELAIEALQTSLGIDVRSKDLEVVVVTKDNSKFTKLTSDQVEHHLNQI 242


>sp|O24362|PRC8_SPIOL PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C8)
           >gi|7435886|pir||T09139 26S proteasome alpha chain -
           spinach >gi|2285802|dbj|BAA21651.1| (D78173) 26S
           proteasome alpha subunit [Spinacia oleracea]
           Length = 249
           
 Score =  151 bits (377), Expect = 9e-36
 Identities = 84/244 (34%), Positives = 130/244 (52%), Gaps = 6/244 (2%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD ++T FSPDGR+FQ+ YA +AV    TAVG+KCKDG+VL VEK I S+++ P S  +
Sbjct: 7   GYDLSVTTFSPDGRVFQIEYAAKAVDNSGTAVGIKCKDGIVLGVEKLIQSKMMLPGSNRR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +  H   A +G+ AD R +V RA+ EA  +   YGE  P+  +  ++     + T Y
Sbjct: 67  IHSVHRHSGMAVAGLAADGRQIVARAKSEATNYESVYGEAVPVKELADRVASYVHLCTLY 126

Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
             +RPFG  +++ G + D P+LY  +PSG  + +   AIG G+  A    E     +MT 
Sbjct: 127 WWLRPFGCGVILGGYDRDGPQLYMVEPSGISYRYFGAAIGKGKQAAKTEIEKLKLSEMTC 186

Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
            E I      + K  ++   +  E+ +  + D+     SK E +K    +++E +     
Sbjct: 187 REGIIEVAKIIYKVHDEAKDKAFELEMSWICDE-----SKREHQKVPDNLLQEAKAAATA 241

Query: 248 EKEE 251
             EE
Sbjct: 242 ALEE 245


>pir||S38529 multicatalytic endopeptidase complex (EC 3.4.99.46) chain XC8 -
           clawed frog
           Length = 255
           
 Score =  149 bits (373), Expect = 3e-35
 Identities = 84/245 (34%), Positives = 132/245 (53%), Gaps = 8/245 (3%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + + FSPDGR+FQV YA +AV+  +TA+ ++CKDGVV  VEK + S+L E  S ++
Sbjct: 7   GYDLSASTFSPDGRVFQVEYAAKAVENSSTAISIRCKDGVVFGVEKLVLSKLYEEGSNKR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           IF +D H+  A +G++ADAR L + AR EA   R  YG   PL  +  ++      +T Y
Sbjct: 67  IFNVDRHVGMAVAGLLADARSLADIAREEASNFRANYGYDIPLKHLSDRVAMYAHAYTLY 126

Query: 129 GGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
             VRPFG + ++   N  D  +LY  DPSG  + +   AIG  +  A    E     ++T
Sbjct: 127 SAVRPFGCSFMLGSYNEDDGAQLYMVDPSGISYGYWGCAIGKAKQAAKTEIEKLQMKELT 186

Query: 187 LDEAIK--LAIFALAKTMEKPSAENIEVA----VITVKDKKFRKLSKEEIEKFLGEVMKE 240
             + +K    I  +     K  +  +E++    +   K +   K  +EE EK+  E ++E
Sbjct: 187 CRDVVKEVAKIIYIVHDEVKDKSFELELSWVGKITNGKHEIVPKDIREEAEKYAKESLEE 246

Query: 241 VEEEE 245
            ++ +
Sbjct: 247 EDDSD 251


>gb|AAC23597.1| (AF070462) proteasome A type subunit [Cryptosporidium parvum]
           Length = 259
           
 Score =  148 bits (370), Expect = 6e-35
 Identities = 93/253 (36%), Positives = 147/253 (57%), Gaps = 11/253 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YD  +  +SP GR+FQ+ YA EAVK+G   VG +  + VVLA  KR TSRL   +  +K+
Sbjct: 6   YDTDVVTWSPQGRVFQIEYAMEAVKQGTAVVGARNDEIVVLACIKRSTSRLAGYQ--KKL 63

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
           ++ID+HI  A SGI ADA+V+ N  R E   +  TY  P PL  +V ++    Q++TQ  
Sbjct: 64  YKIDNHIGVAVSGITADAKVICNYLRSECLNYSFTYDSPIPLNTLVNRLVLKSQVNTQEY 123

Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DMT 186
           G RPFG  LL+AG ++  P L+ET PSG  F + ++AIGS    +    E  +++  + +
Sbjct: 124 GRRPFGVGLLLAGFDESGPHLFETCPSGNCFEYYSIAIGSRSQASKTYLEKHFKEFANCS 183

Query: 187 LDEAIKLAIFALAKTM---EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
            D+ I   + AL  ++   ++ + EN++VA++   D  + +L +EE  K+L  + +E   
Sbjct: 184 KDQLILHTLRALRSSLSSEQEMNQENVDVAILGRND-IYNELLEEEKIKYLQIINQEQPP 242

Query: 244 --EEVKEKEEDYS 254
             E++ E +E  S
Sbjct: 243 TIEQINESQETSS 255


>gb|AAB48404.1| (U73851) 29 kDa proteasome subunit TCPR29 [Trypanosoma cruzi]
           >gi|1857249|gb|AAB48405.1| (U75302) TCPR29 [Trypanosoma
           cruzi]
           Length = 265
           
 Score =  148 bits (369), Expect = 8e-35
 Identities = 103/262 (39%), Positives = 138/262 (52%), Gaps = 18/262 (6%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
           YD   T +SP GRLFQV YA EAV  G+ AVG K KD VVL   KR  S + +  SY EK
Sbjct: 6   YDTNTTTWSPTGRLFQVEYANEAVNNGSAAVGAKNKDFVVLTALKR--SPVAQFSSYQEK 63

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +F++DDH+  A +G++AD R+L    R E   +R  +    PL +I + + +  Q H Q+
Sbjct: 64  VFKLDDHVGMAIAGLVADGRMLARFVRTECMNYRYMHDSDNPLPLIAEIVGEKYQRHIQF 123

Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DM 185
            G RPFG  LL+AG +   P LY T PSG  F +KA A+G     A    E  +    D 
Sbjct: 124 AGKRPFGVGLLIAGYDSTGPHLYHTVPSGDVFDFKATAMGLRSQAARTYLEKHFESFPDC 183

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITV--KDKKFRKLSKEEIEKFL-GEVMK--- 239
            LDE I  A+ ALA      +  NI+   I +  K   F  L++E   K+L G  M+   
Sbjct: 184 GLDELIMHALKALAAATSGGAELNIKNTTIAIVGKGTPFMVLTEEAARKYLDGFKMRPED 243

Query: 240 -----EVEEEE-VKEKEEDYSE 255
                E EEEE ++E+  D  E
Sbjct: 244 IPPAPEAEEEETLQERSLDVEE 265


>gb|AAB48403.1| (U73850) 29 kDa proteasome subunit TCPR29A [Trypanosoma cruzi]
           Length = 265
           
 Score =  148 bits (369), Expect = 8e-35
 Identities = 103/262 (39%), Positives = 138/262 (52%), Gaps = 18/262 (6%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
           YD   T +SP GRLFQV YA EAV  G+ AVG K KD VVL   KR  S + +  SY EK
Sbjct: 6   YDTNTTTWSPTGRLFQVEYANEAVNNGSAAVGTKNKDFVVLTALKR--SPVAQFSSYQEK 63

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +F++DDH+  A +G++AD R+L    R E   +R  +    PL +I + + +  Q H Q+
Sbjct: 64  VFKLDDHVGMAIAGLVADGRMLARFVRTECMNYRYMHDSDNPLPLIAEIVGEKYQRHIQF 123

Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DM 185
            G RPFG  LL+AG +   P LY T PSG  F +KA A+G     A    E  +    D 
Sbjct: 124 AGKRPFGVGLLIAGYDSTGPHLYHTVPSGDVFDFKATAMGLRSQAARTYLEKHFESFPDC 183

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITV--KDKKFRKLSKEEIEKFL-GEVMK--- 239
            LDE I  A+ ALA      +  NI+   I +  K   F  L++E   K+L G  M+   
Sbjct: 184 GLDELIMHALKALAAATSGGAELNIKNTTIAIVGKGTPFMVLTEEAARKYLDGFKMRPED 243

Query: 240 -----EVEEEE-VKEKEEDYSE 255
                E EEEE ++E+  D  E
Sbjct: 244 IPPAPEAEEEETLQERSLDVEE 265


>pir||T41139 proteasome component c1 - fission yeast (Schizosaccharomyces pombe)
           >gi|3080509|emb|CAA18639.1| (AL022598) proteasome
           component c1 [Schizosaccharomyces pombe]
           Length = 253
           
 Score =  147 bits (368), Expect = 1e-34
 Identities = 80/210 (38%), Positives = 120/210 (57%), Gaps = 2/210 (0%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD  +  FSPDGRLFQ  YA +AV+  +T +G+KC+DGV+LA+EK +TS+L++P    +
Sbjct: 7   GYDLGL-FFSPDGRLFQAEYAYKAVENASTCIGIKCEDGVILALEKVVTSKLLKPRVNNR 65

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +D HI  A++G I D + +V RAR EA   R  YG P P  VI  ++ +  Q+ T Y
Sbjct: 66  IGSVDRHIGIATTGFIPDGQHIVKRARDEATSWRDNYGSPIPGTVIADRLGNYVQLFTCY 125

Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
             VRPFG    +A  + + P LY  +P+G Y+ +   A G GR  A    E      + +
Sbjct: 126 SSVRPFGVMSFVATYDSEGPHLYMVEPNGVYWGYNGAAAGKGRQVARNELEKLNFSSLKM 185

Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITV 217
            +A+K A   L  T ++ + +  E+ +  V
Sbjct: 186 KDAVKEAARILYATHDEENNKEHEIEMTWV 215


>gb|AAC32064.1| (AF043528) 20S proteasome subunit PAG1 [Arabidopsis thaliana]
           >gi|3885332|gb|AAC77860.1| (AC005623) 20S proteasome
           subunit C8 (PAG1/PRC8_ARATH) [Arabidopsis thaliana]
           Length = 249
           
 Score =  147 bits (367), Expect = 1e-34
 Identities = 79/244 (32%), Positives = 132/244 (53%), Gaps = 6/244 (2%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD ++T FSPDGR+FQ+ YA +AV    T VG+KCKDG+V+ VEK I S+++ P S  +
Sbjct: 7   GYDLSVTTFSPDGRVFQIEYAAKAVDNSGTVVGIKCKDGIVMGVEKLIASKMMLPGSNRR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +  H   A +G+ AD R +V RA+ EA+ +   YG+  P+  + +++     + T Y
Sbjct: 67  IHSVHRHAGMAVAGLAADGRQIVARAKSEARSYESVYGDAVPVKELSERVASYVHLCTLY 126

Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
             +RPFG  +++ G + D P+LY  +PSG  + +   AIG G+  A    E     +MT 
Sbjct: 127 WWLRPFGCGVILGGYDRDGPQLYMIEPSGISYRYFGAAIGKGKQAAKTEIEKLNLSEMTC 186

Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
            E +      + K  ++   +  E+ +  + ++     SK E +K   ++++E +     
Sbjct: 187 KEGVIEVAKIIYKLHDEAKDKAFELEMSWICEE-----SKREHQKVPDDLLEEAKTAAKT 241

Query: 248 EKEE 251
             EE
Sbjct: 242 ALEE 245


>emb|CAA73625.1| (Y13182) multicatalytic endopeptidase [Arabidopsis thaliana]
           Length = 267
           
 Score =  146 bits (366), Expect = 2e-34
 Identities = 91/238 (38%), Positives = 133/238 (55%), Gaps = 12/238 (5%)

Query: 15  TVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIFQIDD 74
           T +SP GRLFQV YA EAVK+G+ A+G++ +  VVLA   +  S L   +   KIF++DD
Sbjct: 1   TTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RKIFKVDD 58

Query: 75  HIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPF 134
           HI  A +G+ AD RVL    R E+  H  TY  P P+  +V  + D  Q+ TQ    RP+
Sbjct: 59  HIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRSWKRPY 118

Query: 135 GAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDMTLDEAI 191
           G  LL+ G+++    LY   PSG YF ++A AIGS    A    E K+    + + ++ I
Sbjct: 119 GVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERKFESFQESSKEDLI 178

Query: 192 KLAIFALAKTMEKPSAENIEVAVITVK----DKKFRKLSKEEIEKFLGEVMKEVEEEE 245
           K AI A+ +T++    E ++ ++ TV     D+ F  L +E I+K +    K  EEEE
Sbjct: 179 KDAIMAIRETLQ---GETLKSSLCTVSVLGVDEPFHFLDQESIQKVIDTFEKVPEEEE 233


>dbj|BAA96833.1| (AB026562) alpha 7 subunit of 20S proteasome [Oryza sativa]
           Length = 249
           
 Score =  145 bits (361), Expect = 7e-34
 Identities = 80/245 (32%), Positives = 131/245 (52%), Gaps = 3/245 (1%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD ++T FSPDGR+FQV YA +AV    T VG+KCKDG+VL VEK +TS+++   S  +
Sbjct: 7   GYDLSVTTFSPDGRVFQVEYATKAVDNSGTVVGIKCKDGIVLGVEKLVTSKMMLEGSNRR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +  H   A +G+ AD R +V+RA+ EA  +   YGEP  +  +  ++     + T Y
Sbjct: 67  IHSVHWHSGLAVAGLAADGRQIVSRAKSEAASYEKVYGEPISVKELADRVASYVHLCTLY 126

Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
             +RPFG  +++ G + D P+LY  +PSG  + +   A+G GR  A    E     ++T 
Sbjct: 127 WWLRPFGCGVILGGYDRDGPQLYMIEPSGVSYKYFGAALGKGRQAAKTEIEKLKLSELTC 186

Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
            E I      +    ++   +  E+ +  + D+  R+   +++   L E  K   +  ++
Sbjct: 187 REGIVEVAKIIYGVHDEAKDKAFELELSWICDESNRQ--HQKVPADLLEQAKVAAQAALE 244

Query: 248 EKEED 252
           E + D
Sbjct: 245 EMDAD 249


>sp|O23715|PRC8_ARATH PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C8)
           >gi|2511592|emb|CAA74027.1| (Y13693) multicatalytic
           endopeptidase complex, proteasome component, alpha
           subunit [Arabidopsis thaliana]
           Length = 249
           
 Score =  144 bits (360), Expect = 9e-34
 Identities = 78/244 (31%), Positives = 131/244 (52%), Gaps = 6/244 (2%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD ++T FSPDG +FQ+ YA +AV    T VG+KCKDG+V+ VEK I S+++ P S  +
Sbjct: 7   GYDLSVTTFSPDGGVFQIEYAAKAVDNSGTVVGIKCKDGIVMGVEKLIASKMMLPGSNRR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           I  +  H   A +G+ AD R +V RA+ EA+ +   YG+  P+  + +++     + T Y
Sbjct: 67  IHSVHRHAGMAVAGLAADGRQIVARAKSEARSYESVYGDAVPVKELSERVASYVHLCTLY 126

Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
             +RPFG  +++ G + D P+LY  +PSG  + +   AIG G+  A    E     +MT 
Sbjct: 127 WWLRPFGCGVILGGYDRDGPQLYMIEPSGISYRYFGAAIGKGKQAAKTEIEKLNLSEMTC 186

Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
            E +      + K  ++   +  E+ +  + ++     SK E +K   ++++E +     
Sbjct: 187 KEGVIEVAKIIYKLHDEAKDKAFELEMSWICEE-----SKREHQKVPDDLLEEAKTAAKT 241

Query: 248 EKEE 251
             EE
Sbjct: 242 ALEE 245


>gb|AAD52094.1|AF088882_1 (AF088882) 20S proteasome alpha subunit [Leishmania donovani]
           Length = 250
           
 Score =  142 bits (355), Expect = 3e-33
 Identities = 83/244 (34%), Positives = 132/244 (54%), Gaps = 13/244 (5%)

Query: 7   QAGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPES 65
           +AG+D+ ITVFSP+G L+QV YA +AV   G   + ++CKD V++A +  I  RL+ P+S
Sbjct: 3   RAGFDKYITVFSPEGSLYQVEYAFKAVTYPGLLTIAIRCKDAVLVATQHVIPDRLMRPDS 62

Query: 66  YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
              ++++   I    +G   D R LV RAR EA  +   YG   P+AV+ K++ D  Q+ 
Sbjct: 63  VTALYEVTPSIGCCMTGRAPDGRALVQRAREEASDYHYRYGVQIPIAVLAKRMGDKAQVR 122

Query: 126 TQYGGVRPFGAALLMAGVND-------KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE 178
           TQ  G+RP G      G++        KP++Y  DP+G      A A+G  +  AMA  E
Sbjct: 123 TQQAGLRPMGVVSTFIGMDQSDQDGSLKPQIYTVDPAGWTGGHIACAVGKKQVEAMAFLE 182

Query: 179 DKYR----DDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKF 233
            + +    D++T  EA  +A+ AL   +     A+ +EV   T  +  F+++   E+E++
Sbjct: 183 KRQKSTKFDELTQKEAAMIALAALQSAIGTAVKAKEVEVGRCTAANPAFQRVPNSEVEEW 242

Query: 234 LGEV 237
           L  V
Sbjct: 243 LTAV 246


>emb|CAA10314.1| (AJ131148) proteasome subunit alpha-6 [Trypanosoma brucei
           rhodesiense]
           Length = 266
           
 Score =  141 bits (352), Expect = 8e-33
 Identities = 98/254 (38%), Positives = 130/254 (50%), Gaps = 9/254 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
           YD   T +SP GRLFQV YA EAV  G+ AVGVK  D VVL   KR  + +    SY EK
Sbjct: 6   YDTDTTTWSPTGRLFQVEYANEAVNNGSAAVGVKGADYVVLTALKR--NPVSGLSSYQEK 63

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
            F++D+H+  A SG++AD R L    R E   +R  +   APL ++   +    Q H Q+
Sbjct: 64  AFKLDEHVGMAISGLVADGRALSRFLRTECMNYRYMHDSDAPLVMLADIVGAKHQRHIQF 123

Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDM 185
            G RPFG  LL+AG + + P LY+T PSG  F +KA A+G     A    E  +R     
Sbjct: 124 AGKRPFGVGLLIAGYDRQGPRLYQTVPSGDVFDFKATAMGLRSQAARTYLERHFRGFPAC 183

Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITV--KDKKFRKLSKEEIEKFLGEVMKEVEE 243
            LDE +  A+ AL          NI+   I +  K   F  L++EE  K+L       E+
Sbjct: 184 DLDELVMHALRALGAATSGGVELNIKNTTIAIVGKGTPFTILTEEEARKYLDGFKTRPED 243

Query: 244 -EEVKEKEEDYSEL 256
              V + EED  EL
Sbjct: 244 IPAVADNEEDDDEL 257


>sp|P52428|PRC2_ORYSA PROTEASOME COMPONENT C2 (MACROPAIN SUBUNIT C2) (MULTICATALYTIC
           ENDOPEPTIDASE COMPLEX SUBUNIT C2)
           >gi|7435884|pir||T03925 probable multicatalytic
           endopeptidase complex (EC 3.4.99.46) chain C2 - rice
           >gi|1066151|dbj|BAA07128.1| (D37886) proteasome C2
           subunit [Oryza sativa]
           Length = 270
           
 Score =  141 bits (351), Expect = 1e-32
 Identities = 88/250 (35%), Positives = 136/250 (54%), Gaps = 12/250 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YD  +T +SP GRLFQV YA EAVK+G+  VG++ +   VLA   +  S L   +   K+
Sbjct: 6   YDTDVTTWSPAGRLFQVEYAMEAVKQGSACVGLRSRTHAVLAAANKAASELSSHQ--RKV 63

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
           F++ DH   A +G+ AD RVL    R E   H   Y  P P++ +  ++ D  Q+ TQ  
Sbjct: 64  FRVADHAGVALAGLTADGRVLSRFLRSECINHAFVYDAPLPVSRLALRLADKAQVCTQRS 123

Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDMT 186
             RP+G  LL+AG+++    LY   PSG YF ++A AIGS    A    E ++   +D T
Sbjct: 124 WKRPYGVGLLVAGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTFLERRFEGYNDYT 183

Query: 187 LDEAIKLAIFALAKTM--EKPSAENIEVAVITVKD----KKFRKLSKEEIEKFLGEVMKE 240
            ++ IK A+ A+ +T+  EK ++ N  VA++  KD    + F  +  + I++ + + M+ 
Sbjct: 184 PEQLIKDALSAIKETLQGEKLTSSNCTVAIVGRKDDGTVEPFEMIDVKRIQEII-DSMEA 242

Query: 241 VEEEEVKEKE 250
            EE    E E
Sbjct: 243 AEEAPAAEAE 252


>gb|AAC34197.1| (AF017650) testes-specific alpha4 proteasome subunit [Drosophila
           virilis]
           Length = 245
           
 Score =  140 bits (350), Expect = 1e-32
 Identities = 91/240 (37%), Positives = 138/240 (56%), Gaps = 9/240 (3%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           +D ++ ++S DG L QV YA+EAV++G+T VG++ K+ VVL VEKR    L    +  KI
Sbjct: 4   FDESVNIYS-DGHLLQVEYAQEAVRKGST-VGLRTKECVVLGVEKRAIDSLQIERTSRKI 61

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
            +ID H+A   +G+ ADARVLV+RA++EAQ HRL +  PA +  I + +  LKQ +TQ  
Sbjct: 62  KKIDQHMAMTFAGLTADARVLVSRAQVEAQSHRLNFDRPASVEYITRYLARLKQTYTQSV 121

Query: 130 GVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGS-GRNTAMAIFEDKYRDDMT 186
             RPFG + L+ G ++  +P L++TDPSG Y+ W A   G  G+     + ++      T
Sbjct: 122 ARRPFGVSCLIGGFDEDGRPRLFQTDPSGIYYEWSANTTGRLGQTVNEYLEKNTAAISRT 181

Query: 187 LD--EAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
            D   A+K  + AL  T       +IE+AV+    +    +  E +E  LG + +E  EE
Sbjct: 182 PDAASAMKHVVRALF-TATSLDPASIELAVLRYW-QPIEMVKPETLEYLLGVIKQEAVEE 239


>gb|AAF69728.1|AC068783_4 (AC068783) 26S Proteasome alpha subunit [Leishmania major]
           Length = 250
           
 Score =  140 bits (350), Expect = 1e-32
 Identities = 83/244 (34%), Positives = 131/244 (53%), Gaps = 13/244 (5%)

Query: 7   QAGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPES 65
           +AG+D+ ITVFSP+G L+QV YA +AV   G   V ++CKD V++A +  I  RL+ P+S
Sbjct: 3   RAGFDKYITVFSPEGSLYQVEYAFKAVTYPGLLTVAIRCKDAVLVATQHVIPDRLMRPDS 62

Query: 66  YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
              ++++   I    +G   D R LV RAR EA  +   YG   P+AV+ K++ D  Q+ 
Sbjct: 63  VTMLYEVTPGIGCCMTGRAPDGRALVQRAREEASDYHYRYGVQIPIAVLAKRMGDKAQVR 122

Query: 126 TQYGGVRPFGAALLMAGVND-------KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE 178
           TQ  G+RP G      G++        KP++Y  DP+G      A A+G  +  AMA  E
Sbjct: 123 TQQAGLRPMGVVSTFIGMDQSDQDGALKPQIYTVDPAGWTCGHIACAVGKKQVEAMAFLE 182

Query: 179 DKYRD----DMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKF 233
            + +     ++T  EA  +A+ AL   +     A+ +EV   T  +  F+++   E+E++
Sbjct: 183 KRQKSTEFAELTQKEAAMIALAALQSAIGTAVKAKEVEVGRCTAANPAFQRVPNSEVEEW 242

Query: 234 LGEV 237
           L  V
Sbjct: 243 LTAV 246


>gb|AAF58889.1| (AE003832) Prosalpha7 gene product [Drosophila melanogaster]
           Length = 253
           
 Score =  140 bits (349), Expect = 2e-32
 Identities = 79/217 (36%), Positives = 127/217 (58%), Gaps = 15/217 (6%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + + FSPDGR+FQ++YA +AV++  T +G++ KD VVLAVEK ITS+L EP++  +
Sbjct: 7   GYDLSASQFSPDGRVFQIDYASKAVEKSGTVIGIRGKDAVVLAVEKIITSKLYEPDAGGR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           IF I+ +I  A +G++AD   + + AR EA  +R  + +  PL  +  ++      +T Y
Sbjct: 67  IFTIEKNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLY 126

Query: 129 GGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
             VRPFG ++++A  +  + P+LY+ +PSG+ F + A A G  +  A    E K + DM 
Sbjct: 127 SAVRPFGLSIILASWDEVEGPQLYKIEPSGSSFGYFACASGKAKQLAKTEME-KLKMDMR 185

Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFR 223
            DE ++ A   + K  ++            +KDK FR
Sbjct: 186 TDELVESAGEIIYKVHDE------------LKDKDFR 210


>pir||T40592 26s proteasome alpha subunit - fission yeast  (Schizosaccharomyces
           pombe) >gi|4160352|emb|CAA22820.1| (AL035216) 26s
           proteasome alpha subunit [Schizosaccharomyces pombe]
           Length = 244
           
 Score =  139 bits (347), Expect = 3e-32
 Identities = 82/239 (34%), Positives = 133/239 (55%), Gaps = 8/239 (3%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           G+DR ITVFSP+GRL+QV YA +A    G T+VGV  K+   +  +K++  +LI+  + +
Sbjct: 6   GFDRTITVFSPEGRLYQVEYAFKAFNNAGITSVGVTGKNCACVISQKKVPDKLIDASTVK 65

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
            +F I   I    +G IADAR  V+RAR EA       G P P  V+ K++ ++ Q+ TQ
Sbjct: 66  HVFPITKGIGCVMTGSIADARAQVSRARSEAAEFEYKNGYPMPCDVLAKRMANIAQVSTQ 125

Query: 128 YGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD- 184
              +RP G A+ +  V+D+  P L++ DP+G Y  +KA + G  +   +   E +++ D 
Sbjct: 126 RAAMRPLGVAMTLVAVDDEIGPSLFKLDPAGFYIGYKATSAGPKQTETINWLEKRFKKDG 185

Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
               L + ++  I AL  ++     +  +++ V+   DK FR LS EEIE  L  + ++
Sbjct: 186 IPSNLTDTVETGIQALMSSLSTDFKSTELQIGVVE-DDKPFRVLSVEEIEAHLQSIAEK 243


>gb|AAF89683.1|AF169651_1 (AF169651) 20S proteasome alpha 7 subunit [Trypanosoma brucei]
           Length = 237
           
 Score =  138 bits (344), Expect = 7e-32
 Identities = 78/217 (35%), Positives = 122/217 (55%), Gaps = 1/217 (0%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
           +G+D++  +FS DGR+FQV YA +AV  G+TAV   CKDGVV+AVEK +TSR++E  S  
Sbjct: 4   SGHDQSTDIFSADGRVFQVEYACKAVDNGSTAVAACCKDGVVVAVEKILTSRMLEEGSNN 63

Query: 68  KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
           +I  +D        G++ D   +V+RAR EA+  R  +  P   +++  +I +   ++T 
Sbjct: 64  RIHAVDRQAGICVCGVLPDGLAVVSRARGEAENSRDIFSTPILGSLLASRIGEFMHVYTT 123

Query: 128 YGGVRPFGAALLMAG-VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           +   RPFG ++++A   +D P+LY  DPSGA   +  +A+G G+  A    E      +T
Sbjct: 124 HYAYRPFGCSVIIASYADDGPQLYVADPSGAVAGYYGIALGKGKTVAKTELEKLDFATLT 183

Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFR 223
             EA++     L +  +K   +  EV V  V DK  R
Sbjct: 184 CSEAVEKLTNILHEVHDKSKDKIYEVEVAWVCDKSDR 220


>gb|AAB03506.1| (U60168) PrtC [Dictyostelium discoideum]
           Length = 248
           
 Score =  136 bits (340), Expect = 2e-31
 Identities = 83/239 (34%), Positives = 135/239 (55%), Gaps = 12/239 (5%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK- 68
           YD  IT FSP GR+ Q+ YA EAVK+G  AV +K K   VL   KR +S L    SY+K 
Sbjct: 6   YDSDITTFSPSGRIHQIEYAMEAVKQGGAAVALKSKQFAVLVSLKRSSSEL---GSYQKK 62

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           IF +DDH+  A SG+ ADAR+L N  R E   +   Y     +  +V K+ D  Q+HTQ 
Sbjct: 63  IFVVDDHVGIAISGLTADARMLCNYMRNECSNYNYVYESQMRVERLVTKVADKHQVHTQR 122

Query: 129 GGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDM 185
            G RP+G  LL+AG +     +Y+T PSG ++ +K+++IGS   +A    E  +   ++ 
Sbjct: 123 YGRRPYGVGLLVAGYDQLGAHIYQTCPSGNFYDYKSISIGSRSQSAKTYLEKHFESFEEC 182

Query: 186 TLDEAIKLAIFALAKTM----EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
           TL++ I   + AL +T+    +  +++N+ + ++  + + F+ + + + + +L  +  E
Sbjct: 183 TLEQLITHGLRALRETIPNTDDTLNSKNVSIGIVG-EGQPFKIIEEADAQPYLNLLENE 240


>gb|AAC16604.1| (AF027978) 20S proteasome subunit C2 [Gallus gallus]
           Length = 260
           
 Score =  133 bits (331), Expect = 2e-30
 Identities = 84/235 (35%), Positives = 131/235 (55%), Gaps = 11/235 (4%)

Query: 6   PQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPES 65
           P AG D  +TV+SP GR+ Q+ YA EAVK+G+  VG+K K   VL   KR  S L   + 
Sbjct: 3   PVAGSD--VTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ- 59

Query: 66  YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
            +KI  +D+HI  + +G+ ADAR+L N  R E    R  +  P P++ +V  I    Q+ 
Sbjct: 60  -KKILYVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIP 118

Query: 126 TQYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD- 183
           TQ  G RP+G  LL+AG +D  P +++T PS  YF  KA++IG+   +A    E    + 
Sbjct: 119 TQRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCKAMSIGARSQSARNYLERHMTEF 178

Query: 184 -DMTLDEAIKLAIFALAKTM---EKPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
            D  L+E +K  + AL +T+   +  + +N+ + ++  KD +F     +++  FL
Sbjct: 179 TDCNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVG-KDMEFTIYDDDDVAPFL 232


>pir||S64739 multicatalytic endopeptidase complex (EC 3.4.99.46) chain XC9
           (clone 2) - clawed frog (fragment)
           Length = 194
           
 Score =  132 bits (329), Expect = 4e-30
 Identities = 80/188 (42%), Positives = 118/188 (62%), Gaps = 13/188 (6%)

Query: 72  IDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGV 131
           ++D +A + +GI +DA VL N  RL AQ + L Y EP P   +V  +CD+KQ +TQ+GG 
Sbjct: 1   LNDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGK 60

Query: 132 RPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-DMTL 187
           RPFG +LL  G  DK    +LY++DPSG Y  WKA  IG+    A+++ +  Y++ +MTL
Sbjct: 61  RPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTL 119

Query: 188 DEAIKLAIFALAKTME--KPSAENIEVAVITVKD--KKFRKLSKEEIEKFLGEVMKEVEE 243
             A+ LA+  L KTM+  K SAE +E+A +T ++   K R L ++E+E    E++K  EE
Sbjct: 120 KSALALAVKVLNKTMDVSKLSAEKVELATLTRENGKTKIRVLKQKEVE----ELIKLHEE 175

Query: 244 EEVKEKEE 251
           EE K + E
Sbjct: 176 EEAKIERE 183


>gb|AAG28527.1|AF198386_1 (AF198386) 20S proteasome alpha 1 subunit [Trypanosoma brucei]
           Length = 266
           
 Score =  130 bits (323), Expect = 2e-29
 Identities = 80/246 (32%), Positives = 133/246 (53%), Gaps = 14/246 (5%)

Query: 7   QAGYDRAITVFSPDGRLFQVNYAREAVK-RGATAVGVKCKDGVVLAVEKRITSRLIEPES 65
           +AG+D+ ITVFSP+G L+QV YA +AV   G   V ++CKD V++  +  +  +L+ PE+
Sbjct: 3   RAGFDKYITVFSPEGSLYQVEYAFKAVTYAGLLTVAIRCKDAVLVFTQHSVPDKLMRPET 62

Query: 66  YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
              ++ ++D+     +G   D + LV +AR EA  ++  YG P  ++V+ K   D+ Q+ 
Sbjct: 63  ITSLYNVNDNTGVCITGRAPDGKALVQKARNEASEYKYRYGMPMLVSVLAKPWQDMAQVR 122

Query: 126 TQYGGVRPFGAALLMAGV--NDK-----PELYETDPSGAYFAWKAVAIGSGRNTAMAIFE 178
           TQ  G+R  G  +   G+  ND+     P++Y  DP+G   A  A A+G  +  A A  E
Sbjct: 123 TQQAGMRLMGTIMTFVGMEQNDEDGAWIPQIYCVDPAGG-AAVHACAVGKKQIEACAFLE 181

Query: 179 DKYRD----DMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKF 233
            K ++     ++  EA  +A+ AL   + E   A  +EV   T  D  F ++S  E++K+
Sbjct: 182 KKQKNAPFHTLSQKEAAMIALAALQSALGESLRASGVEVGRCTADDHHFLRVSDREVKKW 241

Query: 234 LGEVMK 239
           L  + K
Sbjct: 242 LTPLAK 247


>gi|6321427 Proteasome subunit YC7alpha/Y8 (protease yscE subunit 7); Scl1p
           [Saccharomyces cerevisiae]
           >gi|130858|sp|P21243|PRCI_YEAST PROTEASOME COMPONENT
           C7-ALPHA (MACROPAIN SUBUNIT C7-ALPHA) (PROTEINASE YSCE
           SUBUNIT 7) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX C7)
           (COMPONENT Y8) (SCL1 SUPPRESSOR PROTEIN)
           >gi|67728|pir||SNBYS1 multicatalytic endopeptidase
           complex (EC 3.4.99.46) chain YC7-alpha - yeast
           (Saccharomyces cerevisiae) >gi|11513998|pdb|1G0U|G Chain
           G, A Gated Channel Into The Proteasome Core Particle
           >gi|11514012|pdb|1G0U|U Chain U, A Gated Channel Into
           The Proteasome Core Particle >gi|172266|gb|AAA34909.1|
           (M63641) proteasome Y8 [Saccharomyces cerevisiae]
           >gi|173206|gb|AAA35228.1| (M55440) yeast proteasome
           subunit YC7-alpha [Saccharomyces cerevisiae]
           >gi|506484|emb|CAA40056.1| (X56732) proteasome Y8
           subunit [Saccharomyces cerevisiae]
           >gi|1322467|emb|CAA96711.1| (Z72533) ORF YGL011c
           [Saccharomyces cerevisiae]
           >gi|4261594|gb|AAD13894.1|S58126_111 (S58126) Unknown
           [Saccharomyces cerevisiae] >gi|5734547|emb|CAA40292.1|
           (X56971) proteasome subunit YC7-alpha [Saccharomyces
           cerevisiae] >gi|227817|prf||1712124A proteasome PRS2
           [Saccharomyces cerevisiae]
           Length = 252
           
 Score =  128 bits (318), Expect = 7e-29
 Identities = 84/244 (34%), Positives = 132/244 (53%), Gaps = 13/244 (5%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AGYDR IT+FSP+GRL+QV YA +A  +    ++ V+ KD  V+  +K++  +L++P + 
Sbjct: 10  AGYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTV 69

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             IF I   I    +G I DAR    RA+ EA   R  YG   P  V+ K++ +L Q++T
Sbjct: 70  SYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYT 129

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR-- 182
           Q   +RP G  L    V+++  P +Y+TDP+G Y  +KA A G  +       E+ ++  
Sbjct: 130 QRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKS 189

Query: 183 --DDMTLDEAIKLAIFALAKTMEKPSAE----NIEVAVITVKDKKFRKLSKEEIEKFLGE 236
             D +  +   K+  FA+   ++    E    ++EV V T KD KF  LS E IE+ L  
Sbjct: 190 KIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVAT-KD-KFFTLSAENIEERLVA 247

Query: 237 VMKE 240
           + ++
Sbjct: 248 IAEQ 251


>pdb|1G65|G Chain G, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
           Molecular Basis For Selectivity Of
           Alpha,Beta-Epoxyketone Proteasome Inhibitors
           >gi|11513433|pdb|1G65|U Chain U, Crystal Structure Of
           Epoxomicin:20s Proteasome Reveals A Molecular Basis For
           Selectivity Of Alpha,Beta-Epoxyketone Proteasome
           Inhibitors >gi|3114269|pdb|1RYP|A Chain A, Crystal
           Structure Of The 20s Proteasome From Yeast At 2.4
           Angstroms Resolution >gi|3114283|pdb|1RYP|O Chain O,
           Crystal Structure Of The 20s Proteasome From Yeast At
           2.4 Angstroms Resolution
           Length = 243
           
 Score =  128 bits (318), Expect = 7e-29
 Identities = 84/244 (34%), Positives = 132/244 (53%), Gaps = 13/244 (5%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
           AGYDR IT+FSP+GRL+QV YA +A  +    ++ V+ KD  V+  +K++  +L++P + 
Sbjct: 1   AGYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTV 60

Query: 67  EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
             IF I   I    +G I DAR    RA+ EA   R  YG   P  V+ K++ +L Q++T
Sbjct: 61  SYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYT 120

Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR-- 182
           Q   +RP G  L    V+++  P +Y+TDP+G Y  +KA A G  +       E+ ++  
Sbjct: 121 QRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKS 180

Query: 183 --DDMTLDEAIKLAIFALAKTMEKPSAE----NIEVAVITVKDKKFRKLSKEEIEKFLGE 236
             D +  +   K+  FA+   ++    E    ++EV V T KD KF  LS E IE+ L  
Sbjct: 181 KIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVAT-KD-KFFTLSAENIEERLVA 238

Query: 237 VMKE 240
           + ++
Sbjct: 239 IAEQ 242


>sp|P12881|PRC2_DROME PROTEASOME 29 KDA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 35
           KDA SUBUNIT) >gi|67724|pir||SNFF5K multicatalytic
           endopeptidase complex (EC 3.4.99.46) 35K chain - fruit
           fly (Drosophila melanogaster) >gi|8382|emb|CAA33520.1|
           (X15497) 35 kd proteasome subunit (AA 1 - 279)
           [Drosophila melanogaster] >gi|8388|emb|CAA44173.1|
           (X62285) 35 KDa proteasome  subunit [Drosophila
           melanogaster] >gi|7297622|gb|AAF52875.1| (AE003627)
           Pros35 gene product [Drosophila melanogaster]
           Length = 279
           
 Score =  126 bits (313), Expect = 3e-28
 Identities = 86/251 (34%), Positives = 132/251 (52%), Gaps = 11/251 (4%)

Query: 10  YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
           YD  +TV+SP GRL QV YA EAVK G   VG+K KD  VL    + TS L   ++  KI
Sbjct: 6   YDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSEL--SDTQRKI 63

Query: 70  FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
             IDDH+  + +G+ ADARVL    R E   ++ +Y    P++ ++  + +  Q  TQ  
Sbjct: 64  IPIDDHLGISIAGLTADARVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTTQRY 123

Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DMT 186
             RP+G  LL+AG +++ P +Y+  PS  +F  KA +IGS   +A    E       D +
Sbjct: 124 DRRPYGVGLLVAGYDERGPHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSS 183

Query: 187 LDEAIKLAIFALAKTM----EKPSAENIEVAVITV-KDKKFRKLSKEEIEKFLGEVMKEV 241
            DE I+  I A+  T+    +   A   ++ V  V KD+ F  LS ++  K +  + KE 
Sbjct: 184 KDEIIRHGIRAILGTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDSAKHVA-IAKEN 242

Query: 242 EEEEVKEKEED 252
           + +  +  ++D
Sbjct: 243 DNDTPRNDDDD 253


>gb|AAB82572.1| (AF025793) 20S proteasome alpha7 subunit [Drosophila melanogaster]
           Length = 249
           
 Score =  126 bits (313), Expect = 3e-28
 Identities = 83/246 (33%), Positives = 134/246 (53%), Gaps = 19/246 (7%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD + + FS DGR+FQ++YA +  K G T +G++ KD VVLAVEK ITS+L EP +  +
Sbjct: 7   GYDLSASQFSADGRVFQIDYASKVEKSG-TVIGIRGKDAVVLAVEKIITSKLYEPHAGGR 65

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           IF I+ +I  A +G++AD   + + AR EA  +R  + +  PL  +  ++      +T Y
Sbjct: 66  IFTIEKNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLY 125

Query: 129 GGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
             VRPFG ++++A  +  + P+LY+ +PSG+ F + A A    +  A    E K + DM 
Sbjct: 126 SAVRPFGLSIILASWDEVEGPQLYKIEPSGSSFGYFACA-SKAKQLAKTEME-KLKTDMR 183

Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEV 246
            DE ++ A   + K  ++            +KDK FR      + +  G  +  +   E+
Sbjct: 184 TDELVESAGEIIYKVHDE------------LKDKDFR-FEMGLVGRVTGG-LHLINPSEL 229

Query: 247 KEKEED 252
            EK+ED
Sbjct: 230 TEKDED 235


>pir||T18511 hypothetical protein C0745c - malaria parasite (Plasmodium
           falciparum) >gi|3758867|emb|CAB11152.1| (Z98551)
           proteasome component C8 [Plasmodium falciparum]
           Length = 252
           
 Score =  117 bits (291), Expect = 1e-25
 Identities = 69/245 (28%), Positives = 133/245 (54%), Gaps = 9/245 (3%)

Query: 8   AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAV--EKRITSRLIEPES 65
           AGYD +++ FSPDGRL+QV Y  +++    TA+ ++CKDG++          +++I+  S
Sbjct: 6   AGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNS 65

Query: 66  YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
           Y +I+ ++++I    SG   DAR +++RAR EA  +   +    PL ++V +I      +
Sbjct: 66  YNRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAY 125

Query: 126 TQYGGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD 183
           T Y  +RPF A+++++  N  DK ++Y  +P+GA + +  + IG  +       E K   
Sbjct: 126 TLYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYK 185

Query: 184 DMTLDEAIK-LAIFALAKT--MEKPSAENIEVAVITVKDK--KFRKLSKEEIEKFLGEVM 238
           D+ + +AI+ +  F L     M K + +N+       K+   +F+ + +E +   L + +
Sbjct: 186 DINVRDAIEDIYKFILTSDDHMNKNNLQNLVNFSWICKESSYEFQNIHEEILTPALNKAV 245

Query: 239 KEVEE 243
           + +E+
Sbjct: 246 EYIEK 250


>sp|Q09583|PRC8_CAEEL PUTATIVE PROTEASOME COMPONENT ZK945.2 (MACROPAIN SUBUNIT)
           (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT)
           >gi|7511433|pir||T28119 hypothetical protein ZK945.2 -
           Caenorhabditis elegans >gi|3881887|emb|CAA88436.1|
           (Z48544) contains similarity to Pfam domain: PF00227
           (Proteasome A-type and B-type), Score=200.0,
           E-value=1.2e-56, N=1~cDNA EST yk162f6.3 comes from this
           gene~cDNA EST yk162f6.5 comes from this gene~cDNA EST
           yk404c9.3 comes from this gene~cDNA EST yk40>
           Length = 260
           
 Score =  115 bits (285), Expect = 6e-25
 Identities = 71/237 (29%), Positives = 122/237 (50%), Gaps = 8/237 (3%)

Query: 9   GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
           GYD A + FSPDGR+FQV YA++AV    T + ++ K+GVV+  +K I+S+L    +  +
Sbjct: 7   GYDLAASTFSPDGRIFQVEYAQKAVDNAGTMIAIRGKNGVVVVADKLISSKLYTDNANPR 66

Query: 69  IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
           +F ++D++  A +G   D   L N A  EA      Y EP P+  I   + +   +HT  
Sbjct: 67  MFNVNDNVGVAVAGNYPDGFALKNYAYGEAMKWLKDYREPMPIQNIANSVAEYIHIHT-L 125

Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
           G  RPFGA       N +    L+  +PSG  + +KA A+G  R  A A  E    +++ 
Sbjct: 126 GISRPFGAGAFFMSWNKQTGGRLFLVEPSGLNYEYKAWAVGKHRQAAKAEIEKLKIEELD 185

Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
           +++ +K A   +    ++   +N+++ +  V ++     +  + E+   EV+   EE
Sbjct: 186 VNQLVKEAARIIMVVRDENKDKNVQIEMGWVGEQ-----TNGKYEEVPSEVVTAAEE 237


>gi|11498092 proteasome, subunit beta (psmB) [Archaeoglobus fulgidus]
           >gi|6093784|sp|O29769|PRCB_ARCFU PROTEASOME BETA SUBUNIT
           (MULTICATALYTIC ENDOPEPTIDASE COMPLEX BETA SUBUNIT)
           >gi|7435875|pir||A69310 proteasome, subunit beta (psmB)
           homolog - Archaeoglobus fulgidus
           >gi|2650155|gb|AAB90757.1| (AE001071) proteasome,
           subunit beta (psmB) [Archaeoglobus fulgidus]
           Length = 213
           
 Score =  113 bits (280), Expect = 2e-24
 Identities = 66/212 (31%), Positives = 116/212 (54%), Gaps = 7/212 (3%)

Query: 31  EAVKRGATAVGVKCKDGVVLAVEKRIT-SRLIEPESYEKIFQIDDHIAAASSGIIADARV 89
           E + +G T VG+ CKDGVV+A EKR T    I  ++ +KI+QI D +A  ++G + DA+ 
Sbjct: 6   EKIYKGTTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQF 65

Query: 90  LVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKPE- 148
           L    ++EA ++ +       +  I     +L   +  +    P+   LL+ G++ + + 
Sbjct: 66  LARIIKIEANLYEIRRERKPTVRAIATLTSNLLNSYRYF----PYLVQLLIGGIDSEGKS 121

Query: 149 LYETDPSGAYFAWK-AVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKPSA 207
           +Y  DP G     K  VA GSG  TA  + ED++  ++ +DEA++LA+ A+   M++ SA
Sbjct: 122 IYSIDPIGGAIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSA 181

Query: 208 ENIEVAVITVKDKKFRKLSKEEIEKFLGEVMK 239
               + V+ + + +F + S EE+E+ L +  K
Sbjct: 182 SGDGIDVVKITEDEFYQYSPEEVEQILAKFRK 213


>gb|AAA35020.1| (M31430) scll+ suppressor protein [Saccharomyces cerevisiae]
           Length = 270
           
 Score =  101 bits (248), Expect = 1e-20
 Identities = 72/233 (30%), Positives = 119/233 (50%), Gaps = 13/233 (5%)

Query: 19  PDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIFQIDDHIA 77
           P   ++QV YA +A  +    ++ V+ KD  V+  +K++  +L++P +   IF I   I 
Sbjct: 39  PPRVVYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSYIFCISRTIG 98

Query: 78  AASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAA 137
              +G I DAR    RA+ EA   R  YG   P  V+ K++ +L Q++TQ   +RP G  
Sbjct: 99  MVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVI 158

Query: 138 LLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR----DDMTLDEAI 191
           L    V+++  P +Y+TDP+G Y  +KA A G  +       E+ ++    D +  +   
Sbjct: 159 LTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWE 218

Query: 192 KLAIFALAKTMEKPSAE----NIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
           K+  FA+   ++    E    ++EV V T KD KF  LS E IE+ L  + ++
Sbjct: 219 KVVEFAITHMIDALGTEFSKNDLEVGVAT-KD-KFFTLSAENIEERLVAIAEQ 269


>sp|Q58634|PRCB_METJA PROTEASOME BETA SUBUNIT PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
           COMPLEX BETA SUBUNIT) >gi|2129223|pir||D64454 proteasome
           beta subunit homolog - Methanococcus jannaschii
           >gi|1591869|gb|AAB99241.1| (U67564) proteasome, subunit
           beta (psmB) [Methanococcus jannaschii]
           Length = 224
           
 Score = 97.1 bits (238), Expect = 2e-19
 Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 18/224 (8%)

Query: 33  VKRGATAVGVKCKDGVVLAVEKRIT-SRLIEPESYEKIFQIDDHIAAASSGIIADARVLV 91
           V +G T VG+ C D V+LA +KR +   L+  +  +K+++IDD+IA   +G + DA+ +V
Sbjct: 3   VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62

Query: 92  NRARLEAQIHRLTYGE---PAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVN--DK 146
                EA+++++  G    P   A ++  I    +M        PF   +++ G +  + 
Sbjct: 63  RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF-------PFLTQIIIGGYDLLEG 115

Query: 147 PELYETDPSGAYFAWKA-VAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKP 205
            +L+  DP G     K   A GSG   A  + E  Y  DM+++E IKLA+ AL   ME+ 
Sbjct: 116 AKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERD 175

Query: 206 --SAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
             S   I +AVIT    K      EEIEK L  +  + +++  K
Sbjct: 176 TFSGNGISLAVITKDGVKI--FEDEEIEKILDSMKAKPKKKTTK 217


>gi|6755206 proteasome (prosome, macropain) subunit, beta type 7 [Mus musculus]
           >gi|7435873|pir||JC6122 proteasome beta-type Z chain (EC
           3.4.-.-) - mouse >gi|1632755|dbj|BAA12017.1| (D83585)
           proteasome Z subunit precursor [Mus musculus]
           >gi|2062107|emb|CAA71824.1| (Y10874) proteasome subunti
           MC14 [Mus musculus] >gi|2547068|dbj|BAA22857.1| (D85570)
           PSMB7 [Mus musculus]
           Length = 277
           
 Score = 95.6 bits (234), Expect = 5e-19
 Identities = 81/244 (33%), Positives = 118/244 (48%), Gaps = 21/244 (8%)

Query: 31  EAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEKIFQIDDHIAAASSGIIADARV 89
           +A K G T  GV  KDG+VL  + R T  ++  + +  KI  I  +I    +G  AD  +
Sbjct: 38  KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97

Query: 90  LVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVN-DKPE 148
                    ++H LT G   P  V   ++  LKQM  +Y G    GAAL++ GV+   P 
Sbjct: 98  TTQLISSNLELHSLTTGR-LPRVVTANRM--LKQMLFRYQGY--IGAALVLGGVDVTGPH 152

Query: 149 LYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTM--EKPS 206
           LY   P G+      V +GSG   AMA+FEDK+R DM  +EA KL   A+A  +  +  S
Sbjct: 153 LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGS 212

Query: 207 AENIEVAVI-----------TVKDKKFRKLSKEEIEKFLGEVMKE-VEEEEVKEKEEDYS 254
             NI++ VI           +V +KK  +L +   EK    V+ E V   E++  EE   
Sbjct: 213 GSNIDLCVISKSKLDFLRPFSVPNKKGTRLGRYRCEKGTTAVLTEKVTPLEIEVLEETVQ 272

Query: 255 ELDS 258
            +D+
Sbjct: 273 TMDT 276


>gi|4506203 proteasome (prosome, macropain) subunit, beta type, 7; Z [Homo
           sapiens] >gi|11428779|ref|XP_005463.1| proteasome
           (prosome, macropain) subunit, beta type, 7 [Homo
           sapiens] >gi|1531533|dbj|BAA07238.1| (D38048) proteasome
           subunit z [Homo sapiens]
           Length = 277
           
 Score = 92.4 bits (226), Expect = 5e-18
 Identities = 78/241 (32%), Positives = 115/241 (47%), Gaps = 21/241 (8%)

Query: 34  KRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEKIFQIDDHIAAASSGIIADARVLVN 92
           K G T  GV  KDG+VL  + R T  ++  + +  KI  I  +I    +G  AD  +   
Sbjct: 41  KTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQ 100

Query: 93  RARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVN-DKPELYE 151
                 ++H L+ G   P  V   ++  LKQM  +Y G    GAAL++ GV+   P LY 
Sbjct: 101 LISSNLELHSLSTGR-LPRVVTANRM--LKQMLFRYQGY--IGAALVLGGVDVTGPHLYS 155

Query: 152 TDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTM--EKPSAEN 209
             P G+      V +GSG   AMA+FEDK+R DM  +EA  L   A+A  +  +  S  N
Sbjct: 156 IYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSN 215

Query: 210 IEVAVI-----------TVKDKKFRKLSKEEIEKFLGEVMKE-VEEEEVKEKEEDYSELD 257
           I++ VI           TV +KK  +L +   EK    V+ E +   E++  EE    +D
Sbjct: 216 IDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMD 275

Query: 258 S 258
           +
Sbjct: 276 T 276


>gb|AAF97811.1|AF285103_1 (AF285103) proteasome z subunit [Rattus norvegicus]
           Length = 277
           
 Score = 92.4 bits (226), Expect = 5e-18
 Identities = 80/244 (32%), Positives = 117/244 (47%), Gaps = 21/244 (8%)

Query: 31  EAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEKIFQIDDHIAAASSGIIADARV 89
           +A K G T  GV  KDG+VL  + R T  ++  + +  KI  I  +I    +G  AD  +
Sbjct: 38  KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97

Query: 90  LVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVN-DKPE 148
                    ++H LT G   P  V   ++  LKQM  +Y G    GAAL++ GV+   P 
Sbjct: 98  TTQLISSNLELHSLTTGR-LPRVVTANRM--LKQMLFRYQGY--IGAALVLGGVDVTGPH 152

Query: 149 LYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTM--EKPS 206
           LY   P G+      V +GSG   AMA+FEDK+R DM  +EA KL   A+A  +  +  S
Sbjct: 153 LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGS 212

Query: 207 AENIEVAVI-----------TVKDKKFRKLSKEEIEKFLGEVMKE-VEEEEVKEKEEDYS 254
             NI++ VI           +V +KK  +  +   EK    V+ E V   E++  EE   
Sbjct: 213 GSNIDLCVISKSKLDFLRPYSVPNKKGTRFGRYRCEKGTTAVLTEKVTPLELEVLEEIVQ 272

Query: 255 ELDS 258
            +D+
Sbjct: 273 TMDT 276


>emb|CAB57537.1| (Y18930) proteasome, beta subunit [Sulfolobus solfataricus]
           Length = 225
           
 Score = 84.7 bits (206), Expect = 1e-15
 Identities = 56/207 (27%), Positives = 99/207 (47%), Gaps = 10/207 (4%)

Query: 33  VKRGATAVGVKCKDGVVLAVEKRITSRL-IEPESYEKIFQIDDHIAAASSGIIADARVLV 91
           + +G T VG++  DGV+LA ++R ++   +  +   K+  I D I   ++G +AD + + 
Sbjct: 28  ILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIY 87

Query: 92  NRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKPELYE 151
           +  +     + +T   P  +  I  ++ ++      +    P+   +L+ G +D+P L+ 
Sbjct: 88  DVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYF----PYIVQILIGGYDDQPRLFN 143

Query: 152 TDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKPSAENIE 211
            D  G       VA GSG   AM + ED+Y   MTLDEA  LA  A+   +++ S     
Sbjct: 144 LDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTG 203

Query: 212 VAVITVKDKKFRKLSKEEIEKFLGEVM 238
           V V  +  K       EE+E +L + M
Sbjct: 204 VIVAKIHSK-----GHEELEFYLNKKM 225


>sp|Q9UXF3|PRCB_SULSO PROTEASOME BETA SUBUNIT PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
           COMPLEX BETA SUBUNIT)
           Length = 208
           
 Score = 84.7 bits (206), Expect = 1e-15
 Identities = 56/207 (27%), Positives = 99/207 (47%), Gaps = 10/207 (4%)

Query: 33  VKRGATAVGVKCKDGVVLAVEKRITSRL-IEPESYEKIFQIDDHIAAASSGIIADARVLV 91
           + +G T VG++  DGV+LA ++R ++   +  +   K+  I D I   ++G +AD + + 
Sbjct: 11  ILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIY 70

Query: 92  NRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKPELYE 151
           +  +     + +T   P  +  I  ++ ++      +    P+   +L+ G +D+P L+ 
Sbjct: 71  DVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYF----PYIVQILIGGYDDQPRLFN 126

Query: 152 TDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKPSAENIE 211
            D  G       VA GSG   AM + ED+Y   MTLDEA  LA  A+   +++ S     
Sbjct: 127 LDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTG 186

Query: 212 VAVITVKDKKFRKLSKEEIEKFLGEVM 238
           V V  +  K       EE+E +L + M
Sbjct: 187 VIVAKIHSK-----GHEELEFYLNKKM 208


>emb|CAA73621.1| (Y13178) multicatalytic endopeptidase [Arabidopsis thaliana]
           Length = 273
           
 Score = 82.7 bits (201), Expect = 4e-15
 Identities = 63/227 (27%), Positives = 110/227 (47%), Gaps = 18/227 (7%)

Query: 4   VPPQAGYD----RAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSR 59
           VPP+ G+     +   + +P G       A   +K G T VG+  KDGV+L  + R T  
Sbjct: 8   VPPKGGFSFDLCKRNDMLTPKGLK-----APSFLKTGTTIVGLIFKDGVILGADTRATEG 62

Query: 60  -LIEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKI 118
            ++  ++ EKI  +  +I    +G  AD   + +    + ++HR   G  +    ++  +
Sbjct: 63  PIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTDMVSSQLRLHRYQTGRDSR---VITAL 119

Query: 119 CDLKQMHTQYGGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIF 177
             LK+    Y G     AAL++ GV+   P L+   P G+        +GSG   AM++F
Sbjct: 120 TLLKKHLFSYQG--HVSAALVLGGVDITGPHLHTIYPHGSTDTLPFATMGSGSLAAMSVF 177

Query: 178 EDKYRDDMTLDEAIKLAIFALAKTM--EKPSAENIEVAVITVKDKKF 222
           E KY++ +T DE IKL   ++   +  +  S  N+++ VIT  +K++
Sbjct: 178 EAKYKEGLTRDEGIKLVAESICSGIFNDLGSGSNVDICVITKGNKEY 224


>gb|AAC32067.1| (AF043531) 20S proteasome beta subunit PBB2 [Arabidopsis thaliana]
           >gi|9758084|dbj|BAB08528.1| (AB009052) 20S proteasome
           beta subunit PBB2 [Arabidopsis thaliana]
           Length = 274
           
 Score = 82.7 bits (201), Expect = 4e-15
 Identities = 64/224 (28%), Positives = 109/224 (48%), Gaps = 12/224 (5%)

Query: 4   VPPQAGYDRAITVFSPDGRLFQVNY-AREAVKRGATAVGVKCKDGVVLAVEKRITSR-LI 61
           +PP+ G+  +  +   +  L Q    A   +K G T VG+  KDGV+L  + R T   ++
Sbjct: 8   IPPKGGF--SFDLCKRNDMLTQKGLKAPSFLKTGTTIVGLIFKDGVILGADTRATEGPIV 65

Query: 62  EPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDL 121
             ++ EKI  +  +I    +G  AD   + +    + ++HR   G  +    +V  +  L
Sbjct: 66  ADKNCEKIHYMAPNIYCCGAGTAADTEAVTDMVSSQLRLHRYQTGRDSR---VVTALTLL 122

Query: 122 KQMHTQYGGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
           K+    Y G     AAL++ GV+   P L+   P G+        +GSG   AM++FE K
Sbjct: 123 KKHLFSYQG--HVSAALVLGGVDITGPHLHTIYPHGSTDTLPFATMGSGSLAAMSVFEAK 180

Query: 181 YRDDMTLDEAIKLAIFALAKTM--EKPSAENIEVAVITVKDKKF 222
           Y++ +T DE IKL   A+   +  +  S  N+++ VIT   K++
Sbjct: 181 YKEGLTRDEGIKLVAEAICSGIFNDLGSGSNVDICVITKGHKEY 224


>gb|AAC32066.1| (AF043530) 20S proteasome beta subunit PBB1 [Arabidopsis thaliana]
           >gi|7939516|dbj|BAA95719.1| (AB024028) 20S proteasome
           beta subunit / multicatalytic endopeptidase [Arabidopsis
           thaliana]
           Length = 273
           
 Score = 82.3 bits (200), Expect = 5e-15
 Identities = 63/224 (28%), Positives = 110/224 (48%), Gaps = 12/224 (5%)

Query: 4   VPPQAGYDRAITVFSPDGRLFQVNY-AREAVKRGATAVGVKCKDGVVLAVEKRITSR-LI 61
           VPP+ G+  +  +   +  L Q    A   +K G T VG+  KDGV+L  + R T   ++
Sbjct: 8   VPPKGGF--SFDLCKRNDMLTQKGLKAPSFLKTGTTIVGLIFKDGVILGADTRATEGPIV 65

Query: 62  EPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDL 121
             ++ EKI  +  +I    +G  AD   + +    + ++HR   G  +    ++  +  L
Sbjct: 66  ADKNCEKIHYMAPNIYCCGAGTAADTEAVTDMVSSQLRLHRYQTGRDSR---VITALTLL 122

Query: 122 KQMHTQYGGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
           K+    Y G     AAL++ GV+   P L+   P G+        +GSG   AM++FE K
Sbjct: 123 KKHLFSYQG--HVSAALVLGGVDITGPHLHTIYPHGSTDTLPFATMGSGSLAAMSVFEAK 180

Query: 181 YRDDMTLDEAIKLAIFALAKTM--EKPSAENIEVAVITVKDKKF 222
           Y++ +T DE IKL   ++   +  +  S  N+++ VIT  +K++
Sbjct: 181 YKEGLTRDEGIKLVAESICSGIFNDLGSGSNVDICVITKGNKEY 224


>dbj|BAA19767.1| (D89725) LMP7 [Oryzias latipes]
           Length = 225
           
 Score = 78.0 bits (189), Expect = 1e-13
 Identities = 51/212 (24%), Positives = 97/212 (45%), Gaps = 4/212 (1%)

Query: 29  AREAVKRGATAVGVKCKDGVVLAVEKRI-TSRLIEPESYEKIFQIDDHIAAASSGIIADA 87
           AR  +  G T +  K K GV++AV+ R  T   I    Y K+ +I+ ++    SG  AD 
Sbjct: 14  ARFELHHGTTTLSFKFKHGVIVAVDSRASTGSYIATCEYNKVIEINPYLLGTMSGSAADC 73

Query: 88  RVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKP 147
           +        E +++RL       +A   K +C+   M   Y G+     +++     + P
Sbjct: 74  KYWERLLAKECRLYRLRNNHRISVAAASKLLCN---MMLGYRGMGLSVGSMICGWDKEGP 130

Query: 148 ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKPSA 207
            +Y  D +G   + +  + GSG N A  + +  Y++DMT++EA +L    +     + S 
Sbjct: 131 GIYYVDDNGNRLSGRMFSTGSGSNYAYGVLDSGYKEDMTVEEAYELGRRGIVHATHRDSY 190

Query: 208 ENIEVAVITVKDKKFRKLSKEEIEKFLGEVMK 239
               V +  +++  + K+ K+++ + L    K
Sbjct: 191 SGGVVNMYHIQEDGWIKVCKDDVSELLHHYKK 222


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.317    0.134    0.372 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91647362
Number of Sequences: 2977
Number of extensions: 3661577
Number of successful extensions: 24760
Number of sequences better than 1.0e-10: 217
Number of HSP's better than  0.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 24218
Number of HSP's gapped (non-prelim): 233
length of query: 260
length of database: 189,106,746
effective HSP length: 59
effective length of query: 201
effective length of database: 153,796,013
effective search space: 30912998613
effective search space used: 30912998613
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 164 (68.3 bits)