BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0417 (psmA) DE:proteasome, subunit alpha (EC 3.4.99.46)
(psmA)
(260 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75181 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 515 e-145
sp|O59219|PRCA_PYRHO PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 499 e-140
pir||T43887 proteasome alpha chain [imported] - Thermococcus sp ... 437 e-122
sp|Q60177|PRCA_METJA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 315 4e-85
sp|Q59565|PRCA_METTE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 300 1e-80
gi|11498101 proteasome, subunit alpha (psmA) [Archaeoglobus fulg... 292 2e-78
sp|O26782|PRCA_METTH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 291 6e-78
pir||T48678 proteasome alpha-1 chain [validated] - Haloferax vol... 242 4e-63
sp|Q9YC01|PRCA_AERPE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 231 8e-60
gi|7106389 proteasome (prosome, macropain) subunit, alpha type 7... 220 2e-56
gb|AAK41034.1| Proteasome subunit [Sulfolobus solfataricus] 219 3e-56
emb|CAB57565.1| (Y18930) proteasome alpha subunit (N-terminus) [... 219 3e-56
sp|P48004|PRC6_RAT PROTEASOME SUBUNIT RC6-1 (MULTICATALYTIC ENDO... 218 5e-56
dbj|BAA89276.1| (AB027707) alpha 4 subunit of 20S proteasome [Ca... 218 6e-56
sp|P25156|PRCA_THEAC PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 218 6e-56
gi|4506189 proteasome (prosome, macropain) subunit, alpha type, ... 217 8e-56
gb|AAG18783.1| (AE004983) proteasome, subunit beta; PsmB [Haloba... 217 1e-55
gb|AAC99402.1| (AF054185) proteasome subunit HSPC [Homo sapiens] 216 2e-55
sp|O04861|PRC6_ORYSA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 214 9e-55
dbj|BAA86962.1| (AB004782) 20S proteasome alpha 4 subunit [Xenop... 213 2e-54
dbj|BAA86956.1| (AB027463) 20S proteasome alpha 4 subunit [Xenop... 213 2e-54
pir||JC5510 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 212 3e-54
dbj|BAA76428.1| (AB025000) multicatalytic endopeptidase complex ... 211 8e-54
sp|P30186|PRC6_ARATH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 210 1e-53
gb|AAC32059.1| (AF043523) 20S proteasome subunit PAD2 [Arabidops... 209 2e-53
sp|O24030|PRC6_LYCES PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC EN... 208 7e-53
emb|CAA73622.1| (Y13179) multicatalytic endopeptidase [Arabidops... 207 9e-53
sp|P52427|PRC9_SPIOL PROTEASOME 27 KD SUBUNIT (MULTICATALYTIC EN... 206 2e-52
dbj|BAA99540.1| (AB032061) alpha 4 subunit of 20S proteasome [Or... 206 3e-52
emb|CAA67761.1| (X99382) alpha proteasome [Entamoeba histolytica] 205 3e-52
emb|CAB86711.1| (AL163505) 20S proteasome alpha 5 subunit [Leish... 205 3e-52
gb|AAC32057.1| (AF043521) 20S proteasome subunit PAC1 [Arabidops... 203 1e-51
gb|AAC35982.1| (AF088914) proteasome alpha subunit [Petunia x hy... 203 1e-51
emb|CAA73624.1| (Y13181) multicatalytic endopeptidase [Arabidops... 202 4e-51
sp|P34120|PRC6_DICDI PROTEASOME SUBUNIT DD5 (MULTICATALYTIC ENDO... 201 5e-51
pir||T48679 proteasome alpha-2 chain [validated] - Haloferax vol... 201 7e-51
gb|AAC32061.1| (AF043525) 20S proteasome subunit PAE2 [Arabidops... 199 3e-50
dbj|BAA95822.1| (AP002069) ESTs AU058081(E3082),AU075427(E30384)... 199 3e-50
gb|AAD31877.1|AF140353_1 (AF140353) 20S proteasome alpha 5 subun... 199 3e-50
dbj|BAA96832.1| (AB026561) alpha 5 subunit of 20S proteasome [Or... 199 3e-50
gb|AAF89684.1|AF169652_1 (AF169652) 20S proteasome alpha 4 subun... 198 4e-50
gb|AAC32060.1| (AF043524) 20S proteasome subunit PAE1 [Arabidops... 198 6e-50
dbj|BAA78755.1| (AB023482) ESTs AU058081(E30812),AU058365(E50679... 198 6e-50
pir||T19775 hypothetical protein C36B1.4 - Caenorhabditis elegan... 198 8e-50
gb|AAF34770.1|AF227625_1 (AF227625) proteasome 27 kDa subunit [E... 197 1e-49
gi|6321574 proteasome component Y13; Pre9p [Saccharomyces cerevi... 196 3e-49
gi|6324535 alpha-type of subunit of 20S proteasome; Pre6p [Sacch... 195 5e-49
gb|AAF70292.1|AF255338_1 (AF255338) 20S proteasome subunit [Glyc... 195 5e-49
pir||T38639 proteasome component PUP2 homolog - fission yeast (... 192 3e-48
pdb|1G65|B Chain B, Crystal Structure Of Epoxomicin:20s Proteaso... 192 3e-48
pdb|1G0U|B Chain B, A Gated Channel Into The Proteasome Core Par... 192 3e-48
sp|Q10329|PRC6_SCHPO PUTATIVE PROTEASOME COMPONENT PRE6 (MACROPA... 191 8e-48
pdb|1G0U|C Chain C, A Gated Channel Into The Proteasome Core Par... 191 8e-48
pdb|1G65|C Chain C, Crystal Structure Of Epoxomicin:20s Proteaso... 190 1e-47
sp|Q09682|PRC9_SCHPO PUTATIVE PROTEASOME COMPONENT C9/Y13 (MACRO... 190 2e-47
gi|4506185 proteasome (prosome, macropain) subunit, alpha type, ... 189 2e-47
pir||S17521 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 189 3e-47
gi|7106387 proteasome (prosome, macropain) subunit, alpha type 5... 189 3e-47
gi|8394069 proteasome (prosome, macropain) subunit, alpha type 4... 189 4e-47
gi|6755196 proteasome (prosome, macropain) subunit, alpha type 4... 188 5e-47
sp|Q95083|PRCZ_DROME PROTEASOME PSMA5 SUBUNIT (MULTICATALYTIC EN... 188 7e-47
gb|AAF57875.1| (AE003803) ProsMA5 gene product [Drosophila melan... 187 9e-47
sp|O73672|PRC3_CARAU PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT ... 187 1e-46
pir||S38530 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 187 1e-46
gi|4506187 proteasome (prosome, macropain) subunit, alpha type, ... 187 1e-46
pir||T40971 20s proteasome component C3 - fission yeast (Schizo... 186 2e-46
sp|P34119|PRC9_DICDI PROTEASOME SUBUNIT DD4 (MULTICATALYTIC ENDO... 186 3e-46
sp|P22769|PRC6_DROME PROTEASOME 28 KD SUBUNIT 1 (MULTICATALYTIC ... 185 6e-46
pir||S23451 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 184 7e-46
gi|4506181 proteasome (prosome, macropain) subunit, alpha type, ... 184 7e-46
sp|O23708|PRC3_ARATH PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT ... 184 7e-46
gi|11428206 proteasome (prosome, macropain) subunit, alpha type,... 184 7e-46
gi|8394063 proteasome (prosome, macropain) subunit, alpha type 2... 184 1e-45
gb|AAF05906.1|AF148125_1 (AF148125) 20S proteasome alpha 2 subun... 184 1e-45
emb|CAB62817.1| (AL133435) 20S proteasome alpha 2 subunit [Leish... 184 1e-45
gi|6679497 proteasome (prosome, macropain) subunit, alpha type 2... 183 1e-45
sp|P24495|PRC3_XENLA PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT ... 183 2e-45
gi|8394072 proteasome (prosome, macropain) subunit, alpha type 5... 183 2e-45
dbj|BAA96830.1| (AB026559) alpha 2 subunit of 20S proteasome [Or... 182 3e-45
gb|AAC34196.1| (AF017649) alpha4 proteasome subunit [Drosophila ... 182 4e-45
gb|AAF60416.1| (AC006708) contains similarity to Pfam family PF0... 179 2e-44
sp|P40301|PRC3_DROME PROTEASOME 25 KDA SUBUNIT (MULTICATALYTIC E... 179 3e-44
gb|AAF46651.1| (AE003452) Pros29 gene product [Drosophila melano... 179 3e-44
sp|P18053|PRC9_DROME PROTEASOME 29 KD SUBUNIT (MULTICATALYTIC EN... 177 1e-43
gi|6321692 Proteasome subunit; Pup2p [Saccharomyces cerevisiae] ... 174 8e-43
pdb|1G0U|D Chain D, A Gated Channel Into The Proteasome Core Par... 174 8e-43
emb|CAA46111.1| (X64918) PUP2 [Saccharomyces cerevisiae] 173 2e-42
emb|CAA74025.1| (Y13691) multicatalytic endopeptidase complex, p... 170 1e-41
dbj|BAB09993.1| (AB023031) multicatalytic endopeptidase complex ... 170 1e-41
pdb|1G65|D Chain D, Crystal Structure Of Epoxomicin:20s Proteaso... 169 3e-41
emb|CAB95217.1| (AL359773) proteasome subunit [Leishmania major] 169 3e-41
gb|AAC32054.1| (AF043518) 20S proteasome subunit PAA1 [Arabidops... 169 4e-41
gb|AAG28528.1|AF198387_1 (AF198387) 20S proteasome alpha 3 subun... 168 5e-41
pir||S72226 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 168 6e-41
gb|AAF47215.1| (AE003464) Pros28.1B gene product [Drosophila mel... 167 1e-40
pir||T02089 proteasome chain - rice >gi|2570505|gb|AAB82138.1| (... 167 1e-40
gb|AAF55802.1| (AE003731) Pros28.1A gene product [Drosophila mel... 166 2e-40
gb|AAB34631.1| Doa5, PUP2=alpha-type proteasome subunit zeta hom... 166 2e-40
pir||T21350 hypothetical protein F25H2.9 - Caenorhabditis elegan... 166 2e-40
emb|CAB39975.1| (Y16644) PRCI [Nicotiana tabacum] 165 4e-40
pir||T06142 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 165 5e-40
gi|6323547 proteasome component Y7; Pre8p [Saccharomyces cerevis... 164 1e-39
gi|6324938 proteasome component YC1 (protease yscE subunit 1); P... 163 2e-39
gb|AAC32055.1| (AF043519) 20S proteasome subunit PAA2 [Arabidops... 162 3e-39
sp|Q27488|PRC3_CAEEL PROBABLE PROTEASOME COMPONENT C3 (MACROPAIN... 161 6e-39
sp|Q27563|PRC8_DICDI PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT ... 161 8e-39
pdb|1G65|F Chain F, Crystal Structure Of Epoxomicin:20s Proteaso... 161 1e-38
pdb|1G0U|F Chain F, A Gated Channel Into The Proteasome Core Par... 161 1e-38
dbj|BAA96829.1| (AB026558) alpha 1 subunit of 20S proteasome [Or... 160 1e-38
gb|AAF59183.1| (AE003839) Prosalpha1 gene product [alt 1] [Droso... 160 2e-38
pir||S72225 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 159 2e-38
gi|8394076 proteasome (prosome, macropain) subunit, alpha type 6... 159 3e-38
sp|P90513|PRC8_ACACA PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT ... 159 3e-38
gi|6755198 proteasome (prosome, macropain) subunit, alpha type 6... 158 5e-38
gb|AAD33944.1|AF144749_1 (AF144749) 20S proteasome subunit alpha... 158 7e-38
gi|8394066 proteasome (prosome, macropain) subunit, alpha type 3... 156 3e-37
gi|4506183 proteasome (prosome, macropain) subunit, alpha type, ... 155 6e-37
emb|CAA62960.1| (X91847) proteasome subunit C9-like protein [Sus... 154 8e-37
gi|6755194 proteasome (prosome, macropain) subunit, alpha type 3... 154 8e-37
sp|P34066|PRC2_ARATH PROTEASOME, 30 KD SUBUNIT (MULTICATALYTIC E... 152 5e-36
gb|AAC32062.1| (AF043526) 20S proteasome subunit PAF1 [Arabidops... 152 5e-36
gb|AAC32063.1| (AF043527) 20S proteasome subunit PAF2 [Arabidops... 152 5e-36
pir||T19320 hypothetical protein C15H11.7 - Caenorhabditis elega... 151 7e-36
sp|O24362|PRC8_SPIOL PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT ... 151 9e-36
pir||S38529 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 149 3e-35
gb|AAC23597.1| (AF070462) proteasome A type subunit [Cryptospori... 148 6e-35
gb|AAB48404.1| (U73851) 29 kDa proteasome subunit TCPR29 [Trypan... 148 8e-35
gb|AAB48403.1| (U73850) 29 kDa proteasome subunit TCPR29A [Trypa... 148 8e-35
pir||T41139 proteasome component c1 - fission yeast (Schizosacch... 147 1e-34
gb|AAC32064.1| (AF043528) 20S proteasome subunit PAG1 [Arabidops... 147 1e-34
emb|CAA73625.1| (Y13182) multicatalytic endopeptidase [Arabidops... 146 2e-34
dbj|BAA96833.1| (AB026562) alpha 7 subunit of 20S proteasome [Or... 145 7e-34
sp|O23715|PRC8_ARATH PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT ... 144 9e-34
gb|AAD52094.1|AF088882_1 (AF088882) 20S proteasome alpha subunit... 142 3e-33
emb|CAA10314.1| (AJ131148) proteasome subunit alpha-6 [Trypanoso... 141 8e-33
sp|P52428|PRC2_ORYSA PROTEASOME COMPONENT C2 (MACROPAIN SUBUNIT ... 141 1e-32
gb|AAC34197.1| (AF017650) testes-specific alpha4 proteasome subu... 140 1e-32
gb|AAF69728.1|AC068783_4 (AC068783) 26S Proteasome alpha subunit... 140 1e-32
gb|AAF58889.1| (AE003832) Prosalpha7 gene product [Drosophila me... 140 2e-32
pir||T40592 26s proteasome alpha subunit - fission yeast (Schiz... 139 3e-32
gb|AAF89683.1|AF169651_1 (AF169651) 20S proteasome alpha 7 subun... 138 7e-32
gb|AAB03506.1| (U60168) PrtC [Dictyostelium discoideum] 136 2e-31
gb|AAC16604.1| (AF027978) 20S proteasome subunit C2 [Gallus gallus] 133 2e-30
pir||S64739 multicatalytic endopeptidase complex (EC 3.4.99.46) ... 132 4e-30
gb|AAG28527.1|AF198386_1 (AF198386) 20S proteasome alpha 1 subun... 130 2e-29
gi|6321427 Proteasome subunit YC7alpha/Y8 (protease yscE subunit... 128 7e-29
pdb|1G65|G Chain G, Crystal Structure Of Epoxomicin:20s Proteaso... 128 7e-29
sp|P12881|PRC2_DROME PROTEASOME 29 KDA SUBUNIT (MULTICATALYTIC E... 126 3e-28
gb|AAB82572.1| (AF025793) 20S proteasome alpha7 subunit [Drosoph... 126 3e-28
pir||T18511 hypothetical protein C0745c - malaria parasite (Plas... 117 1e-25
sp|Q09583|PRC8_CAEEL PUTATIVE PROTEASOME COMPONENT ZK945.2 (MACR... 115 6e-25
gi|11498092 proteasome, subunit beta (psmB) [Archaeoglobus fulgi... 113 2e-24
gb|AAA35020.1| (M31430) scll+ suppressor protein [Saccharomyces ... 101 1e-20
sp|Q58634|PRCB_METJA PROTEASOME BETA SUBUNIT PRECURSOR (MULTICAT... 97 2e-19
gi|6755206 proteasome (prosome, macropain) subunit, beta type 7 ... 96 5e-19
gi|4506203 proteasome (prosome, macropain) subunit, beta type, 7... 92 5e-18
gb|AAF97811.1|AF285103_1 (AF285103) proteasome z subunit [Rattus... 92 5e-18
emb|CAB57537.1| (Y18930) proteasome, beta subunit [Sulfolobus so... 85 1e-15
sp|Q9UXF3|PRCB_SULSO PROTEASOME BETA SUBUNIT PRECURSOR (MULTICAT... 85 1e-15
emb|CAA73621.1| (Y13178) multicatalytic endopeptidase [Arabidops... 83 4e-15
gb|AAC32067.1| (AF043531) 20S proteasome beta subunit PBB2 [Arab... 83 4e-15
gb|AAC32066.1| (AF043530) 20S proteasome beta subunit PBB1 [Arab... 82 5e-15
dbj|BAA19767.1| (D89725) LMP7 [Oryzias latipes] 78 1e-13
>pir||B75181 multicatalytic endopeptidase complex (EC 3.4.99.46) alpha chain
PAB0417 - Pyrococcus abyssi (strain Orsay)
>gi|5458039|emb|CAB49529.1| (AJ248284) proteasome,
subunit alpha (EC 3.4.99.46) (psmA) [Pyrococcus abyssi]
Length = 260
Score = 515 bits (1312), Expect = e-145
Identities = 260/260 (100%), Positives = 260/260 (100%)
Query: 1 MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL
Sbjct: 1 MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
Query: 61 IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD
Sbjct: 61 IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK
Sbjct: 121 LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE
Sbjct: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
Query: 241 VEEEEVKEKEEDYSELDSHY 260
VEEEEVKEKEEDYSELDSHY
Sbjct: 241 VEEEEVKEKEEDYSELDSHY 260
>sp|O59219|PRCA_PYRHO PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|7435878|pir||A71033 probable
proteasome, alpha subunit - Pyrococcus horikoshii
>gi|3257982|dbj|BAA30665.1| (AP000006) 260aa long
hypothetical proteasome, alpha subunit [Pyrococcus
horikoshii]
Length = 260
Score = 499 bits (1271), Expect = e-140
Identities = 249/260 (95%), Positives = 258/260 (98%)
Query: 1 MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKC +GVVLAVEKRITSRL
Sbjct: 1 MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCNEGVVLAVEKRITSRL 60
Query: 61 IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD
Sbjct: 61 IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
LKQMHTQYGGVRPFGAALLMAGVN+KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE+K
Sbjct: 121 LKQMHTQYGGVRPFGAALLMAGVNEKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEEK 180
Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
Y+DDM+L+EAIKLAIFALAKTMEKPSAENIEVA+ITVKDKKFRKLS+EEIEK+L EVMKE
Sbjct: 181 YKDDMSLEEAIKLAIFALAKTMEKPSAENIEVAIITVKDKKFRKLSREEIEKYLNEVMKE 240
Query: 241 VEEEEVKEKEEDYSELDSHY 260
VEEEEVKEKEEDYSELDSHY
Sbjct: 241 VEEEEVKEKEEDYSELDSHY 260
>pir||T43887 proteasome alpha chain [imported] - Thermococcus sp
>gi|2398843|dbj|BAA22211.1| (AB001084) proteasome alpha
subunit [Thermococcus sp. KS-1]
Length = 260
Score = 437 bits (1111), Expect = e-122
Identities = 215/260 (82%), Positives = 242/260 (92%)
Query: 1 MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVK KDGVVLAVEKRITS+L
Sbjct: 1 MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKWKDGVVLAVEKRITSKL 60
Query: 61 IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
IEP SYEKIF IDDHIAAA SGIIADARVLV+RARLEAQI+RLTYGEP PL V+VKKICD
Sbjct: 61 IEPSSYEKIFLIDDHIAAAPSGIIADARVLVDRARLEAQIYRLTYGEPVPLTVLVKKICD 120
Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
LKQ HTQYGGVRPFGAALLMAGVN+KPEL+ETDPSGAYF WKAVAIGSGRNTAMAIFE+
Sbjct: 121 LKQAHTQYGGVRPFGAALLMAGVNEKPELFETDPSGAYFEWKAVAIGSGRNTAMAIFEEH 180
Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
YRDD+ D+AIKLAI ALAKT+E+P+AE IEVA IT+ +K+++KL +EE+EK+L E+++E
Sbjct: 181 YRDDIGKDDAIKLAILALAKTLEEPTAEGIEVAYITMDEKRWKKLPREELEKYLNEILQE 240
Query: 241 VEEEEVKEKEEDYSELDSHY 260
V+EEEV+EK+EDYSELD +Y
Sbjct: 241 VKEEEVEEKQEDYSELDQNY 260
>sp|Q60177|PRCA_METJA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) (20S PROTEASOME ALPHA SUBUNIT)
>gi|2118152|pir||G64373 proteasome alpha subunit homolog
- Methanococcus jannaschii >gi|1591299|gb|AAB98581.1|
(U67507) proteasome, subunit alpha (psmA) [Methanococcus
jannaschii]
Length = 261
Score = 315 bits (798), Expect = 4e-85
Identities = 154/251 (61%), Positives = 202/251 (80%), Gaps = 2/251 (0%)
Query: 1 MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
M VPP A YDRAITVFSP+GRL+QV YAREAV+RG TA+G+ CKDGVVLAV++RITS+L
Sbjct: 1 MQMVPPSA-YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKL 59
Query: 61 IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
++ S EKIFQIDDH+AAA+SG++ADARVL++RARLEAQI+RLTYGE + ++ KKICD
Sbjct: 60 VKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICD 119
Query: 121 LKQMHTQYGGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFED 179
+KQ +TQ+GGVRPFG +LL+AG++ ++ L+ETDPSGA +KA AIGSGR M + E
Sbjct: 120 IKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK 179
Query: 180 KYRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMK 239
+YRDD+TLDE ++LAI AL K E EN++V +ITVKD +F+K+ EEI+K + +V K
Sbjct: 180 EYRDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKK 239
Query: 240 EVEEEEVKEKE 250
++ EE KE+E
Sbjct: 240 KLNEENKKEEE 250
>sp|Q59565|PRCA_METTE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|11265947|pir||T48878 proteasome psmA,
alpha chain [validated] - Methanosarcina thermophila
>gi|1002689|gb|AAA93166.1| (U30483) PsmA [Methanosarcina
thermophila]
Length = 247
Score = 300 bits (760), Expect = 1e-80
Identities = 152/245 (62%), Positives = 193/245 (78%), Gaps = 2/245 (0%)
Query: 6 PQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPES 65
PQ GYDRAITVFSPDGRLFQV YAREAVKRG TAVG+K DGVVL V+KRITSRL+E ES
Sbjct: 3 PQMGYDRAITVFSPDGRLFQVEYAREAVKRGTTAVGIKAADGVVLLVDKRITSRLVEAES 62
Query: 66 YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
EKIFQIDDHI AA+SG++ADAR LV+RAR+EAQ++R++Y E + VI KKICD KQ +
Sbjct: 63 IEKIFQIDDHIGAATSGLVADARALVDRARVEAQVNRVSYDELIGVEVISKKICDHKQTY 122
Query: 126 TQYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
TQYGGVRP+G ALL+AGV+DK P L+ETDPSGA +KA AIG+GRN + +FE Y++D
Sbjct: 123 TQYGGVRPYGTALLIAGVDDKRPRLFETDPSGALLEYKATAIGAGRNAVVEVFEADYKED 182
Query: 185 MTLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
M ++ AI L + AL K E K A +EV V++++DKKFRKL EE+ ++ +++++ +E
Sbjct: 183 MNIEAAILLGMDALYKAAEGKFDAGTLEVGVVSLQDKKFRKLEPEEVGNYVQQILEKHKE 242
Query: 244 EEVKE 248
E KE
Sbjct: 243 TENKE 247
>gi|11498101 proteasome, subunit alpha (psmA) [Archaeoglobus fulgidus]
>gi|6093781|sp|O29760|PRCA_ARCFU PROTEASOME ALPHA
SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX ALPHA
SUBUNIT) >gi|7435882|pir||B69311 proteasome, subunit
alpha (psmA) homolog - Archaeoglobus fulgidus
>gi|2650136|gb|AAB90747.1| (AE001070) proteasome,
subunit alpha (psmA) [Archaeoglobus fulgidus]
Length = 246
Score = 292 bits (740), Expect = 2e-78
Identities = 137/239 (57%), Positives = 186/239 (77%), Gaps = 1/239 (0%)
Query: 6 PQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPES 65
PQ GYDRAITVFSPDGRLFQV YAREAVKRGATA+G+KCK+GV+L +KR+ S+L+E ++
Sbjct: 4 PQMGYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVGSKLLEADT 63
Query: 66 YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
EKI++ID+HI AA+SG++ADARVL++RAR+EAQI+RLTY EP + + KKICD KQ +
Sbjct: 64 IEKIYKIDEHICAATSGLVADARVLIDRARIEAQINRLTYDEPITVKELAKKICDFKQQY 123
Query: 126 TQYGGVRPFGAALLMAGVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
TQYGGVRPFG +LL+AGV++ P+LYETDPSGA +KA AIG GRN FE +YRDD+
Sbjct: 124 TQYGGVRPFGVSLLIAGVDEVPKLYETDPSGALLEYKATAIGMGRNAVTEFFEKEYRDDL 183
Query: 186 TLDEAIKLAIFALAKTMEKPSA-ENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
+ D+A+ L + A+ ++E ENIEV + V D+ F+++S EE++ ++ + + E
Sbjct: 184 SFDDAMVLGLVAMGLSIESELVPENIEVGYVKVDDRTFKEVSPEELKPYVERANERIRE 242
>sp|O26782|PRCA_METTH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|7435881|pir||D69191 proteasome, alpha
subunit - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621771|gb|AAB85191.1| (AE000848)
proteasome, alpha subunit [Methanobacterium
thermoautotrophicum]
Length = 248
Score = 291 bits (737), Expect = 6e-78
Identities = 147/242 (60%), Positives = 191/242 (78%), Gaps = 4/242 (1%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
AGYDRAITVFSPDGRLFQV YAREAVKRG T++GVK K+G+VL V+KR TS+L+EP+S E
Sbjct: 7 AGYDRAITVFSPDGRLFQVEYAREAVKRGTTSLGVKSKEGIVLVVDKRPTSKLVEPKSIE 66
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KIFQID+HI AA+SG++ADAR ++ +ARLEAQI+R+TY EP + + KKICD+KQM+TQ
Sbjct: 67 KIFQIDEHIGAATSGLVADARAIIEKARLEAQINRITYNEPIRVESLAKKICDMKQMYTQ 126
Query: 128 YGGVRPFGAALLMAGVNDKP-ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
+GGVRPFG AL++ GVN + L+ETDPSGA +KA AIG+GR AM FE KY DDM
Sbjct: 127 HGGVRPFGTALIIGGVNGRGCRLFETDPSGALIEYKATAIGAGRPAAMEEFEKKYSDDMN 186
Query: 187 LDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVM--KEVEE 243
L++AI+LA+ A+ + E K + E++E+AVI DKK+R+L +EI + E++ KE EE
Sbjct: 187 LNQAIELALDAVYEATEGKTTPESVEIAVIEAADKKYRRLPDDEIRDHVEELLIRKEKEE 246
Query: 244 EE 245
EE
Sbjct: 247 EE 248
>pir||T48678 proteasome alpha-1 chain [validated] - Haloferax volcanii
>gi|5833206|gb|AAD53404.1|AF126260_1 (AF126260) alpha-1
subunit of 20S proteasome [Haloferax volcanii]
Length = 252
Score = 242 bits (610), Expect = 4e-63
Identities = 121/246 (49%), Positives = 174/246 (70%), Gaps = 4/246 (1%)
Query: 7 QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
Q YDR IT+FSPDGRL+QV YAREAVKRG ++GV+ +GVVLA +KR S L+EP S
Sbjct: 7 QQAYDRGITIFSPDGRLYQVEYAREAVKRGTASIGVRTPEGVVLAADKRSRSPLMEPTSV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
EKI + DDHI AS+G +ADAR L++ AR ++Q++RL YGEP + + K++ D Q +T
Sbjct: 67 EKIHKADDHIGIASAGHVADARQLIDFARHQSQVNRLRYGEPIGIETLTKEVTDHIQQYT 126
Query: 127 QYGGVRPFGAALLMAGV-NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
Q GG RPFG ALL+ GV N P LYETDPSG + WKAV+IG+ R E+ +RDD+
Sbjct: 127 QVGGARPFGVALLIGGVENGTPRLYETDPSGTPYEWKAVSIGADRGDHQEHLEENFRDDL 186
Query: 186 TLDEAIKLAIFALAKTMEKPSA-ENIEVAVITVKDKKFRKLSKEEIEKFL--GEVMKEVE 242
TLDE I+LA+ A+A T ++ +A + ++VA ++ + ++F +LS +EIE +L +++ +
Sbjct: 187 TLDEGIELALEAIASTSDEGTAPDGVDVATVSAETERFVELSNDEIESYLEANDLLATED 246
Query: 243 EEEVKE 248
+E+ +E
Sbjct: 247 DEQTEE 252
>sp|Q9YC01|PRCA_AERPE PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|7435889|pir||A72624 probable
proteasome, alpha subunit APE1449 - Aeropyrum pernix
(strain K1) >gi|5105133|dbj|BAA80447.1| (AP000061) 258aa
long hypothetical proteasome , alpha subunit [Aeropyrum
pernix]
Length = 258
Score = 231 bits (582), Expect = 8e-60
Identities = 119/255 (46%), Positives = 174/255 (67%), Gaps = 14/255 (5%)
Query: 1 MAF-VPP-QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITS 58
MAF +PP Q YDRA T+FSP+G L+QV YA EAVK+G T++G+K +GVV+A EKR
Sbjct: 1 MAFPMPPHQTAYDRAATIFSPEGDLYQVRYAFEAVKKGWTSLGIKTNEGVVIAAEKRFIG 60
Query: 59 RLIEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKI 118
L++ + +KI++IDDHI A +G+ D R+L++ AR+ HRL YGEP P+ ++ K +
Sbjct: 61 PLVDIDDIDKIYKIDDHIGVAFAGMGGDGRILIDYARVFTVRHRLLYGEPPPVELVAKVV 120
Query: 119 CDLKQMHTQYGGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAI 176
D+KQ +TQ+GGVRPFG AL+ AGVN ++Y TDP G YF++KA+AIGSG A +
Sbjct: 121 ADVKQAYTQHGGVRPFGVALIFAGVNPDGTTKVYRTDPGGQYFSFKAIAIGSGEQVANEM 180
Query: 177 FEDKYRDDMTLDEAIKLAIFAL----AKTMEKPS------AENIEVAVITVKDKKFRKLS 226
FE YR DM+L+EA KLA+ L KT+E + +E+A ITVK++ F K++
Sbjct: 181 FEKHYRSDMSLEEATKLALKILYAIIRKTVEDKEKAIATLPDQVELAYITVKERMFTKMT 240
Query: 227 KEEIEKFLGEVMKEV 241
KE++++ + + +E+
Sbjct: 241 KEQVKEIVDSMREEL 255
>gi|7106389 proteasome (prosome, macropain) subunit, alpha type 7 [Mus
musculus] >gi|3805978|gb|AAC69150.1| (AF019662) C6-I
proteasome chain; PSMA7 [Mus musculus]
Length = 248
Score = 220 bits (554), Expect = 2e-56
Identities = 120/246 (48%), Positives = 164/246 (65%), Gaps = 6/246 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ KD VVL VEK+ ++L + + KI
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+DD++ A +G+ ADAR+++NRAR+E Q HRLT +P + I + I LKQ +TQ
Sbjct: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
G RPFG + L+ G + P LY+TDPSG Y AWKA AIG G + E Y DD
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
T D IKL I AL + ++ +NIE+AV+ +D+ + L+ EEIEK++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILNPEEIEKYVAEIEKEKEENE 240
Query: 246 VKEKEE 251
K++++
Sbjct: 241 KKKQKK 246
>gb|AAK41034.1| Proteasome subunit [Sulfolobus solfataricus]
Length = 241
Score = 219 bits (552), Expect = 3e-56
Identities = 110/238 (46%), Positives = 160/238 (67%), Gaps = 4/238 (1%)
Query: 1 MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
MAF P GYDRAIT+FSPDG L+QV+YA EAVK+G TA+G+K K VV+A EKR L
Sbjct: 1 MAFGPAAMGYDRAITIFSPDGSLYQVDYAFEAVKKGWTAIGIKSKSSVVIASEKRKAQSL 60
Query: 61 IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
++ +S EK+F IDDH+ + +G+ +D RVL++ AR A HRL Y EP + + K + D
Sbjct: 61 LDVDSIEKVFLIDDHVGCSFAGLASDGRVLIDYARNIALQHRLIYDEPVSIDYLTKSVAD 120
Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFED 179
+KQM+TQ+GGVRPFG AL++AG++ P+L+ T+PSG Y ++AVAIG G TA E
Sbjct: 121 VKQMYTQHGGVRPFGVALVIAGIDKSVPKLFMTEPSGQYMPYQAVAIGQGYYTATEFLEK 180
Query: 180 KYRDDMTLDEAIKLAIFALAKTM---EKPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
Y++D+ ++E I LA+ AL+ T+ EK + +E+ + + F K++ E+ +L
Sbjct: 181 NYKEDLNVEETILLALKALSATLKPNEKLTPNTVEIGYASTQTGLFLKMTNEDKNMYL 238
>emb|CAB57565.1| (Y18930) proteasome alpha subunit (N-terminus) [Sulfolobus
solfataricus]
Length = 241
Score = 219 bits (552), Expect = 3e-56
Identities = 110/238 (46%), Positives = 160/238 (67%), Gaps = 4/238 (1%)
Query: 1 MAFVPPQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRL 60
MAF P GYDRAIT+FSPDG L+QV+YA EAVK+G TA+G+K K VV+A EKR L
Sbjct: 1 MAFGPAAMGYDRAITIFSPDGSLYQVDYAFEAVKKGWTAIGIKSKSSVVIASEKRKAQSL 60
Query: 61 IEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICD 120
++ +S EK+F IDDH+ + +G+ +D RVL++ AR A HRL Y EP + + K + D
Sbjct: 61 LDVDSIEKVFLIDDHVGCSFAGLASDGRVLIDYARNIALQHRLIYDEPVSIDYLTKSVAD 120
Query: 121 LKQMHTQYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFED 179
+KQM+TQ+GGVRPFG AL++AG++ P+L+ T+PSG Y ++AVAIG G TA E
Sbjct: 121 VKQMYTQHGGVRPFGVALVIAGIDKSVPKLFMTEPSGQYMPYQAVAIGQGYYTATEFLEK 180
Query: 180 KYRDDMTLDEAIKLAIFALAKTM---EKPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
Y++D+ ++E I LA+ AL+ T+ EK + +E+ + + F K++ E+ +L
Sbjct: 181 NYKEDLNVEETILLALKALSATLKPNEKLTPNTVEIGYASTQTGLFLKMTNEDKNMYL 238
>sp|P48004|PRC6_RAT PROTEASOME SUBUNIT RC6-1 (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
SUBUNIT RC6-1) >gi|2118151|pir||S60038 multicatalytic
endopeptidase complex (EC 3.4.99.46) alpha chain RC6-I -
rat >gi|1089797|dbj|BAA06463.1| (D30804) proteasome
subunit RC6-1 [Rattus rattus]
Length = 254
Score = 218 bits (550), Expect = 5e-56
Identities = 122/252 (48%), Positives = 166/252 (65%), Gaps = 12/252 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ +D VVL VEK+ ++L + + KI
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62
Query: 70 FQIDDH------IAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQ 123
+DD+ + A+ SG+ ADAR+++NRAR+E Q HRLT G+P + I + I LKQ
Sbjct: 63 CALDDNVCMAFAVVASVSGLTADARIVINRARVECQSHRLTVGDPVTVEYITRYIASLKQ 122
Query: 124 MHTQYGGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
+TQ G RPFG + L+ G + P LY+TDPSG Y AWKA AIG G + E Y
Sbjct: 123 RYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY 182
Query: 182 RDDM--TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMK 239
DD T D IKL I AL + ++ +NIE+AV+ +D+ + LS EEIEK++ E+ K
Sbjct: 183 TDDAIETDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILSPEEIEKYVAEIEK 240
Query: 240 EVEEEEVKEKEE 251
E EE E K++++
Sbjct: 241 EKEENEKKKQKK 252
>dbj|BAA89276.1| (AB027707) alpha 4 subunit of 20S proteasome [Carassius auratus]
Length = 251
Score = 218 bits (549), Expect = 6e-56
Identities = 120/251 (47%), Positives = 164/251 (64%), Gaps = 6/251 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
A YDRAITVFSPDG LFQV YA+EAVK+G+TAVG++ KD VVL VEK+ ++L E +
Sbjct: 3 ARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGKDIVVLGVEKKSVAKLQEERTVR 62
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI +D+H+ A +G+ ADAR+++NRAR+E Q HRLT +P + I + I LKQ +TQ
Sbjct: 63 KICALDEHVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIATLKQRYTQ 122
Query: 128 YGGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
G RPFG + L+ G + P LY+TDPSG Y AWKA AIG T E Y D+
Sbjct: 123 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTDEA 182
Query: 186 TL--DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
++AIKLAI AL + ++ +NIE+AVI +++ + L +EIE + E+ KE EE
Sbjct: 183 IASDNDAIKLAIKALLEVVQS-GGKNIELAVIR-RNQPLKILESKEIETLVAEIEKEKEE 240
Query: 244 EEVKEKEEDYS 254
E K+K++ S
Sbjct: 241 EAEKKKQKKSS 251
>sp|P25156|PRCA_THEAC PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|1076173|pir||S55350 multicatalytic
endopeptidase complex (EC 3.4.99.46) alpha chain -
Thermoplasma acidophilum >gi|1633359|pdb|1PMA|A Chain A,
Proteasome From Thermoplasma Acidophilum
>gi|1633361|pdb|1PMA|C Chain C, Proteasome From
Thermoplasma Acidophilum >gi|1633362|pdb|1PMA|D Chain D,
Proteasome From Thermoplasma Acidophilum
>gi|1633363|pdb|1PMA|E Chain E, Proteasome From
Thermoplasma Acidophilum >gi|1633364|pdb|1PMA|F Chain F,
Proteasome From Thermoplasma Acidophilum
>gi|1633365|pdb|1PMA|G Chain G, Proteasome From
Thermoplasma Acidophilum >gi|1633366|pdb|1PMA|H Chain H,
Proteasome From Thermoplasma Acidophilum
>gi|1633367|pdb|1PMA|I Chain I, Proteasome From
Thermoplasma Acidophilum >gi|1633368|pdb|1PMA|J Chain J,
Proteasome From Thermoplasma Acidophilum
>gi|1633369|pdb|1PMA|K Chain K, Proteasome From
Thermoplasma Acidophilum >gi|1633370|pdb|1PMA|L Chain L,
Proteasome From Thermoplasma Acidophilum
>gi|1633371|pdb|1PMA|M Chain M, Proteasome From
Thermoplasma Acidophilum >gi|1633372|pdb|1PMA|N Chain N,
Proteasome From Thermoplasma Acidophilum
>gi|1633373|pdb|1PMA|O Chain O, Proteasome From
Thermoplasma Acidophilum >gi|395159|emb|CAA42094.1|
(X59507) alpha-subunit of the proteasome [Thermoplasma
acidophilum] >gi|10640633|emb|CAC12411.1| (AL445067)
proteasome alpha subunit [Thermoplasma acidophilum]
Length = 233
Score = 218 bits (549), Expect = 6e-56
Identities = 113/230 (49%), Positives = 164/230 (71%), Gaps = 3/230 (1%)
Query: 7 QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
Q YDRAITVFSPDGRLFQV YAREAVK+G+TA+G+K +GV+L +K++ SRLIE S
Sbjct: 5 QMAYDRAITVFSPDGRLFQVEYAREAVKKGSTALGMKFANGVLLISDKKVRSRLIEQNSI 64
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
EKI IDD++AA +SG++ADARVLV+ AR+ AQ ++TYG + +VK++ D Q +T
Sbjct: 65 EKIQLIDDYVAAVTSGLVADARVLVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYT 124
Query: 127 QYGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
QYGGVRP+G +L+ AG++ P L++ DP+G +KA AIGSG++ ++ E +Y++++
Sbjct: 125 QYGGVRPYGVSLIFAGIDQIGPRLFDCDPAGTINEYKATAIGSGKDAVVSFLEREYKENL 184
Query: 186 TLDEAIKLAIFALAKTMEK-PSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
EA+ L I AL ++E+ + E+A ITV K+R +EE++KFL
Sbjct: 185 PEKEAVTLGIKALKSSLEEGEELKAPEIASITV-GNKYRIYDQEEVKKFL 233
>gi|4506189 proteasome (prosome, macropain) subunit, alpha type, 7 [Homo
sapiens] >gi|11421089|ref|XP_009560.1| proteasome
(prosome, macropain) subunit, alpha type, 7 [Homo
sapiens] >gi|2555136|gb|AAB81515.1| (AF022815)
proteasome subunit XAPC7 [Homo sapiens]
Length = 248
Score = 217 bits (548), Expect = 8e-56
Identities = 118/246 (47%), Positives = 164/246 (65%), Gaps = 6/246 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ +D VVL VEK+ ++L + + KI
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+DD++ A +G+ ADAR+++NRAR+E Q HRLT +P + I + I LKQ +TQ
Sbjct: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
G RPFG + L+ G + P LY+TDPSG Y AWKA AIG G + E Y D+
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
T D IKL I AL + ++ +NIE+AV+ +D+ + L+ EEIEK++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQSLKILNPEEIEKYVAEIEKEKEENE 240
Query: 246 VKEKEE 251
K++++
Sbjct: 241 KKKQKK 246
>gb|AAG18783.1| (AE004983) proteasome, subunit beta; PsmB [Halobacterium sp. NRC-1]
Length = 253
Score = 217 bits (547), Expect = 1e-55
Identities = 110/247 (44%), Positives = 160/247 (64%), Gaps = 2/247 (0%)
Query: 7 QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
Q YDR IT+FSPDGRL+QV YAREAVKRG ++GV+ +GVVL V+K+ S L+E S
Sbjct: 7 QQAYDRGITIFSPDGRLYQVEYAREAVKRGTASIGVRTPEGVVLVVDKQTRSPLLEGSSV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
EK+ +IDDH+ AAS+G +ADAR LV+ AR ++Q+ R+ Y EP + + K + D Q +T
Sbjct: 67 EKLHKIDDHVGAASAGHVADARQLVDFARQQSQVERVRYDEPIGVRTLTKSVTDHIQQYT 126
Query: 127 QYGGVRPFGAALLMAGV-NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
Q GG RPFG ALL+AGV +P L+ETDPSG WKAVAIGS R ED+Y +
Sbjct: 127 QVGGARPFGVALLIAGVEGGEPRLFETDPSGTSNEWKAVAIGSNRGDIQEFLEDEYDAGL 186
Query: 186 TLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
++D+ I LA+ AL + E S + + V ++ +R+L+ +E + ++ ++ ++
Sbjct: 187 SVDDGIDLALRALNEGREDALSGDGVGVGIVDADTGTYRELAADESQSYIDDIEDAADDS 246
Query: 245 EVKEKEE 251
+ + EE
Sbjct: 247 DDDDDEE 253
>gb|AAC99402.1| (AF054185) proteasome subunit HSPC [Homo sapiens]
Length = 248
Score = 216 bits (545), Expect = 2e-55
Identities = 117/246 (47%), Positives = 164/246 (66%), Gaps = 6/246 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ +D VVL VEK+ ++L + + KI
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+DD++ A +G+ ADAR+++NRAR+E Q HRLT +P + I + I LKQ +TQ
Sbjct: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
G RPFG + L+ G + P LY+TDPSG Y AWKA +IG G + E Y D+
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANSIGRGAKSVREFLEKNYTDEAIE 182
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
T D IKL I AL + ++ +NIE+AV+ +D+ + L+ EEIEK++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQSLKILNPEEIEKYVAEIEKEKEENE 240
Query: 246 VKEKEE 251
K++++
Sbjct: 241 KKKQKK 246
>sp|O04861|PRC6_ORYSA PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|7435885|pir||T04300 probable
multicatalytic endopeptidase complex (EC 3.4.99.46)
alpha chain - rice >gi|1930070|gb|AAB51521.1| (U92540)
proteasome alpha subunit [Oryza sativa]
Length = 249
Score = 214 bits (539), Expect = 9e-55
Identities = 121/245 (49%), Positives = 159/245 (64%), Gaps = 6/245 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
A YDRAITVFSPDG LFQV YA EAV++G AVGV+ D VVL VEK+ T +L + S
Sbjct: 2 ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTVVLGVEKKSTPKLQDSRSMR 61
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI +D HIA A +G+ ADARVL+NRAR+E Q HRLT +P + I + I L+Q +TQ
Sbjct: 62 KIASLDTHIALACAGLKADARVLINRARVECQSHRLTVEDPVTVEYITRYIAGLQQKYTQ 121
Query: 128 YGGVRPFGAALLMAGVN---DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
GGVRPFG + L+ G + +KP LY+TDPSG + AWKA A G N+ E Y+ D
Sbjct: 122 SGGVRPFGLSTLIVGFDPYTEKPALYQTDPSGTFSAWKANATGRNSNSMREFLEKNYK-D 180
Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
+ E IKLAI AL + +E +NIE+AV+T KD R+L + EI++++ E+ E
Sbjct: 181 TSGKETIKLAIRALLEVVES-GGKNIEIAVMTHKD-GLRELEEAEIDEYVAEIEAEKAAA 238
Query: 245 EVKEK 249
E +K
Sbjct: 239 EAAKK 243
>dbj|BAA86962.1| (AB004782) 20S proteasome alpha 4 subunit [Xenopus laevis]
Length = 248
Score = 213 bits (536), Expect = 2e-54
Identities = 116/246 (47%), Positives = 164/246 (66%), Gaps = 6/246 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ K+ VVL VEK+ ++L + + KI
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKEIVVLGVEKKSVAKLQDERTVRKI 62
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+D+++ A +G+ ADAR+++NRAR+E Q HRLT +P + I + I LKQ +TQ
Sbjct: 63 CALDENVFMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
G RPFG + L+ G + P LY+TDPSG Y AWKA AIG G + E Y D+
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKHYTDEAIE 182
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
T D IKL I AL + ++ +NIE+AV+ +D+ + L+ EEIE+++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILNPEEIERYVAEIEKEKEENE 240
Query: 246 VKEKEE 251
K++++
Sbjct: 241 KKKQKK 246
>dbj|BAA86956.1| (AB027463) 20S proteasome alpha 4 subunit [Xenopus laevis]
Length = 247
Score = 213 bits (536), Expect = 2e-54
Identities = 116/246 (47%), Positives = 164/246 (66%), Gaps = 6/246 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ K+ VVL VEK+ ++L + + KI
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKEIVVLGVEKKSVAKLQDERTVRKI 62
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+D+++ A +G+ ADAR+++NRAR+E Q HRLT +P + I + I LKQ +TQ
Sbjct: 63 CALDENVFMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
G RPFG + L+ G + P LY+TDPSG Y AWKA AIG G + E Y D+
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKHYTDEAIE 182
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
T D IKL I AL + ++ +NIE+AV+ +D+ + L+ EEIE+++ E+ KE EE E
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILNPEEIERYVAEIEKEKEENE 240
Query: 246 VKEKEE 251
K++++
Sbjct: 241 KKKQKK 246
>pir||JC5510 multicatalytic endopeptidase complex (EC 3.4.99.46) alpha chain -
chicken >gi|485265|gb|AAC60206.1| (U09226) proteasome 28
kDa subunit homolog, similar to Swiss-Prot Accession
Number P22769 [Gallus gallus]
Length = 249
Score = 212 bits (535), Expect = 3e-54
Identities = 120/247 (48%), Positives = 164/247 (65%), Gaps = 7/247 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRAITVFSPDG LFQV YA+EAVK+G+TAVGV+ KD VVL VEK+ ++L + + KI
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+DD++ A +G+ ADAR+++NRAR+E Q HRLT +P + I + I LKQ +TQ
Sbjct: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSK 122
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM-- 185
RPFG + L+ G + P LY+TDPSG Y AWKA AIG G + FE Y D+
Sbjct: 123 RRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVRVEFEKNYTDEAIE 182
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKL-SKEEIEKFLGEVMKEVEEE 244
T D IKL I AL + ++ +NIE+AV+ +D+ + L S EEIEK++ E+ KE EE
Sbjct: 183 TDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQPLKILTSPEEIEKYVAEIEKEKEEN 240
Query: 245 EVKEKEE 251
E K++++
Sbjct: 241 EKKKQKK 247
>dbj|BAA76428.1| (AB025000) multicatalytic endopeptidase complex [Cicer arietinum]
Length = 249
Score = 211 bits (531), Expect = 8e-54
Identities = 118/245 (48%), Positives = 157/245 (63%), Gaps = 6/245 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
A YDRAITVFSPDG LFQV YA EAV++G AVGV+ D VVL VEK+ T++L + S
Sbjct: 2 ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDNVVLGVEKKSTAKLQDTRSVR 61
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI +DDHIA A +G+ ADARVL+NRAR+E Q HRLT +P + I + I L+Q +TQ
Sbjct: 62 KIVNLDDHIALACAGLKADARVLINRARVECQSHRLTVEDPVTVEYITRYIAGLQQKYTQ 121
Query: 128 YGGVRPFGAALLMAGVN---DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
GGVRPFG + L+ G + P LY+TDPSG + AWKA A G N+ E ++ +
Sbjct: 122 SGGVRPFGLSTLIVGFDPYTGSPSLYQTDPSGTFSAWKANATGRNSNSIREFLEKNFK-E 180
Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
+ E +KLAI AL + +E +NIEVAV+T K+ R+L + EI+ + E+ E
Sbjct: 181 TSGQETVKLAIRALLEVVES-GGKNIEVAVMT-KENGLRQLEEAEIDAIVAEIEAEKAAA 238
Query: 245 EVKEK 249
E +K
Sbjct: 239 EAAKK 243
>sp|P30186|PRC6_ARATH PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) (TAS-G64) >gi|478764|pir||S29240
multicatalytic endopeptidase complex (EC 3.4.99.46)
alpha chain - Arabidopsis thaliana
>gi|16445|emb|CAA47298.1| (X66825) proteosome alpha
subunit [Arabidopsis thaliana]
>gi|3421080|gb|AAC32058.1| (AF043522) 20S proteasome
subunit PAD1 [Arabidopsis thaliana]
>gi|6562278|emb|CAB62648.1| (AL132980) multicatalytic
endopeptidase complex [Arabidopsis thaliana]
>gi|742351|prf||2009376B proteasome:SUBUNIT=alpha
[Arabidopsis thaliana]
Length = 250
Score = 210 bits (529), Expect = 1e-53
Identities = 117/245 (47%), Positives = 157/245 (63%), Gaps = 5/245 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
A YDRAITVFSPDG LFQV YA EAV++G AVGV+ D VVLAVEK+ T +L + S
Sbjct: 2 ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTVVLAVEKKSTPKLQDSRSAR 61
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI +D+HIA A +G+ ADARVL+N+AR+E Q HRLT +P + I + I L+Q +TQ
Sbjct: 62 KIVSLDNHIALACAGLKADARVLINKARIECQSHRLTLEDPVTVEYITRYIAGLQQKYTQ 121
Query: 128 YGGVRPFGAALLMAGVNDK---PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
GGVRPFG + L+ G + P LY+TDPSG + AWKA A G N+ E Y++
Sbjct: 122 SGGVRPFGLSTLIVGFDPYTRIPALYQTDPSGTFSAWKANATGRNSNSIREFLEKNYKES 181
Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
E +KLAI AL + +E +NIEVAV+T ++ ++L +EEI+ + E+ E
Sbjct: 182 AG-QETVKLAIRALLEVVES-GGKNIEVAVMTREEGVLKQLEEEEIDIIVAEIEAEKAAA 239
Query: 245 EVKEK 249
E +K
Sbjct: 240 EAAKK 244
>gb|AAC32059.1| (AF043523) 20S proteasome subunit PAD2 [Arabidopsis thaliana]
>gi|10177129|dbj|BAB10419.1| (AB011474) 20S proteasome
subunit PAD2 [Arabidopsis thaliana]
Length = 250
Score = 209 bits (527), Expect = 2e-53
Identities = 117/245 (47%), Positives = 157/245 (63%), Gaps = 5/245 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
A YDRAITVFSPDG LFQV YA EAV++G AVGV+ D VVLAVEK+ T +L + S
Sbjct: 2 ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTVVLAVEKKSTPKLQDSRSAR 61
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI +D+HIA A +G+ ADARVL+N+AR+E Q HRLT +P + I + I L+Q +TQ
Sbjct: 62 KIVSLDNHIALACAGLKADARVLINKARIECQSHRLTLEDPVTVEYITRYIAGLQQKYTQ 121
Query: 128 YGGVRPFGAALLMAGVND---KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
GGVRPFG + L+ G + P LY+TDPSG + AWKA A G N+ E Y++
Sbjct: 122 SGGVRPFGLSTLIVGFDPYSRLPSLYQTDPSGTFSAWKANATGRNSNSIREFLEKNYKES 181
Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
+ E IKLAI AL + +E +NIEVAV+T ++ R+L + EI+ + ++ E
Sbjct: 182 -SGQETIKLAIRALLEVVES-GGKNIEVAVMTREETGLRQLEEAEIDAIVAKIEAEKAAA 239
Query: 245 EVKEK 249
E +K
Sbjct: 240 EAAKK 244
>sp|O24030|PRC6_LYCES PROTEASOME ALPHA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
ALPHA SUBUNIT) >gi|7435877|pir||T07744 multicatalytic
endopeptidase complex (EC 3.4.99.46) alpha chain -
tomato >gi|2315211|emb|CAA74725.1| (Y14339) proteasome
alpha subunit [Lycopersicon esculentum]
Length = 259
Score = 208 bits (523), Expect = 7e-53
Identities = 117/245 (47%), Positives = 156/245 (62%), Gaps = 6/245 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
A YDRAITVFSPDG LFQV YA EAV++G AVGV+ D VVL VEK+ T +L + S
Sbjct: 2 ARYDRAITVFSPDGHLFQVEYAMEAVRKGNAAVGVRGTDTVVLGVEKKSTPKLQDSRSVR 61
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI +DDHIA A +G+ ADARVLVN+AR+E Q HRLT +P + I + I L+Q +TQ
Sbjct: 62 KIVNLDDHIALACAGLKADARVLVNKARIECQSHRLTVEDPVTVEYITRYIAGLQQKYTQ 121
Query: 128 YGGVRPFGAALLMAGVNDK---PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
GGVRPFG + L+ G + P LY+TDPSG + AWKA A G N+ E Y+ +
Sbjct: 122 SGGVRPFGLSTLIIGFDPHTGVPSLYQTDPSGTFSAWKANATGRNSNSTREFLEKNYK-E 180
Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
+ E +KLAI AL + +E +NIEVAV+T K+ ++L + EI+ + E+ E
Sbjct: 181 TSGQETVKLAIRALLEVVES-GGKNIEVAVMT-KEHGLKQLEEAEIDAIVAEIEAEKAAA 238
Query: 245 EVKEK 249
E ++
Sbjct: 239 EAAKR 243
>emb|CAA73622.1| (Y13179) multicatalytic endopeptidase [Arabidopsis thaliana]
>gi|2511582|emb|CAA73623.1| (Y13180) multicatalytic
endopeptidase [Arabidopsis thaliana]
Length = 235
Score = 207 bits (522), Expect = 9e-53
Identities = 115/236 (48%), Positives = 154/236 (64%), Gaps = 5/236 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
A YDRAITVFSPDG LFQV YA EAV++G AVGV+ D VVLAVEK+ T +L + S
Sbjct: 2 ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTVVLAVEKKSTPKLQDSRSAR 61
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI +D+HIA A +G+ ADARVL+N+AR+E Q HRLT +P + I + I L+Q +TQ
Sbjct: 62 KIVSLDNHIALACAGLKADARVLINKARIECQSHRLTLEDPVTVEYITRYIAGLQQKYTQ 121
Query: 128 YGGVRPFGAALLMAGVND---KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
GGVRPFG + L+ G + P LY+TDPSG + AWKA A G N+ E Y++
Sbjct: 122 SGGVRPFGLSTLIVGFDPYSRLPSLYQTDPSGTFSAWKANATGRNSNSIREFLEKNYKES 181
Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
+ E IKLAI AL + +E +NIEVAV+T ++ R+L + EI+ + ++ E
Sbjct: 182 -SGQETIKLAIRALLEVVES-GGKNIEVAVMTREETGLRQLEEAEIDAIVAKIEAE 235
>sp|P52427|PRC9_SPIOL PROTEASOME 27 KD SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 27
KD SUBUNIT) >gi|7435866|pir||T09160 proteasome subunit -
spinach >gi|1262146|emb|CAA65660.1| (X96974) proteasome
subunit [Spinacia oleracea]
Length = 250
Score = 206 bits (519), Expect = 2e-52
Identities = 104/235 (44%), Positives = 160/235 (67%), Gaps = 8/235 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA EA+ +A+G+ KDGVVL EK++TS+L++ S EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILAKDGVVLIGEKKVTSKLLQTSTSTEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+++IDDH+A A +GI++DA +L+N AR++AQ + +Y EP P+ +V+ +CD KQ +TQ+
Sbjct: 65 MYKIDDHVACAVAGIMSDANILINTARVQAQRYTFSYQEPMPVEQLVQSLCDTKQGYTQF 124
Query: 129 GGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+RPFG + L AG N +LY +DPSG Y WKA AIG+ A ++ + Y+DD+T
Sbjct: 125 GGLRPFGVSFLFAGWDKNYGFQLYMSDPSGNYGGWKATAIGANNQAAQSMLKQDYKDDVT 184
Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITVKDK---KFRKLSKEEIEKFLGE 236
++A+KLA+ AL+KTM+ S +E +E+A + + K++ S E + + L E
Sbjct: 185 REDAVKLALKALSKTMDSTSLTSEKLELAEVYLLPSGKVKYQVHSPESLNRLLTE 239
>dbj|BAA99540.1| (AB032061) alpha 4 subunit of 20S proteasome [Oryza sativa]
Length = 248
Score = 206 bits (518), Expect = 3e-52
Identities = 120/245 (48%), Positives = 157/245 (63%), Gaps = 7/245 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
A YDRAITVFSPDG LFQV YA EAV++G AVGV+ D VVL VEK+ T +L + S
Sbjct: 2 ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGSDTVVLGVEKKSTPKLQDSRSVR 61
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI +D HIA A +G+ ADARVL NRAR+E Q HRLT + + I + I L+Q +TQ
Sbjct: 62 KIASLDTHIALACAGLKADARVL-NRARVECQSHRLTVEDAVTVEYITRYIAGLQQKYTQ 120
Query: 128 YGGVRPFGAALLMAGVN---DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
GGVRPFG + L+ G + DKP LY+TDPSG + AWKA A G N+ E Y+ +
Sbjct: 121 SGGVRPFGLSTLIVGFDPYTDKPALYQTDPSGTFSAWKANATGRNSNSMREFLEKNYK-E 179
Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
+ E IKLAI AL + +E +NIE+AV+T KD R+L + EI++++ E+ E
Sbjct: 180 TSGKETIKLAIRALLEVVES-GGKNIEIAVMTQKD-GLRQLEEAEIDEYVAEIEAEKAAA 237
Query: 245 EVKEK 249
E +K
Sbjct: 238 EAAKK 242
>emb|CAA67761.1| (X99382) alpha proteasome [Entamoeba histolytica]
Length = 247
Score = 205 bits (517), Expect = 3e-52
Identities = 113/238 (47%), Positives = 155/238 (64%), Gaps = 7/238 (2%)
Query: 11 DRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIF 70
D + FS +GRLFQV YA EA+K G+T +G++ K+GVVLAVEKRI+S L+ S EKI
Sbjct: 9 DHGVNTFSSEGRLFQVEYATEAMKLGSTVIGIQTKEGVVLAVEKRISSPLMLGSSIEKII 68
Query: 71 QIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGG 130
+IDDHI AA SG+ ADAR L++ ARLEAQ HR Y EP + V+ + I DL +
Sbjct: 69 EIDDHIGAAVSGLTADARTLIDNARLEAQNHRFMYDEPINVEVVAQAISDLSLRFGEGSR 128
Query: 131 -----VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
RPFG ALL+AGV++ P L++TDPSG + + A A G+G A +I +KY
Sbjct: 129 KKKVMSRPFGVALLIAGVDETGPRLFQTDPSGMFIEFYAKATGAGTEAAQSILHEKYNKS 188
Query: 185 MTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEV 241
MTL EA LA+ L + M EK +++N+EVA++TV+ KKF + IE +GE+ +E+
Sbjct: 189 MTLREAEILALSTLKQVMEEKLNSKNVEVALVTVEKKKFEIMDTAFIENLIGEIKEEL 246
>emb|CAB86711.1| (AL163505) 20S proteasome alpha 5 subunit [Leishmania major]
Length = 244
Score = 205 bits (517), Expect = 3e-52
Identities = 107/235 (45%), Positives = 150/235 (63%), Gaps = 7/235 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GR+FQ+ YA EA+K G+T++G++ GVVLA EKR+ S L+ P S KI
Sbjct: 8 YDRGVNTFSPEGRIFQIEYAVEAIKLGSTSLGIRTPKGVVLAAEKRVPSTLVVPSSMSKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HIAA SG++ADAR+LV AR+E+Q HR TY EP + CDL + G
Sbjct: 68 MEIDSHIAAVMSGMVADARILVEHARVESQNHRFTYNEPMSVESCTLATCDLSIQFGESG 127
Query: 130 G-----VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD 183
G RPFG +LL+AGV++K P+L++TDPSG + + A AIG G A ++F ++Y
Sbjct: 128 GKRKLMSRPFGVSLLIAGVDEKGPQLWQTDPSGTHTRYDAQAIGGGAEAAQSVFTERYHR 187
Query: 184 DMTLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
+MTL+E LA+ L + ME + S ENIEVAV+ D K + EI+ + +
Sbjct: 188 NMTLEEGETLAVDILKQVMEDQLSPENIEVAVVRADDGKLHMYTPTEIKAIMSRM 242
>gb|AAC32057.1| (AF043521) 20S proteasome subunit PAC1 [Arabidopsis thaliana]
>gi|9229453|dbj|BAA99919.1| (AP001306) 20S proteasome
subunit PAC1 (gb|AAC32057.1) [Arabidopsis thaliana]
Length = 250
Score = 203 bits (512), Expect = 1e-51
Identities = 103/233 (44%), Positives = 155/233 (66%), Gaps = 8/233 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA EA+ +A+G+ KDGVVL EK++TS+L++ S EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+++IDDH+A A +GI++DA +L+N AR++AQ + Y EP P+ +V+ +CD KQ +TQ+
Sbjct: 65 MYKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQF 124
Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+RPFG + L AG + +LY +DPSG Y WKA A+G+ A +I + Y+DD T
Sbjct: 125 GGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYKDDAT 184
Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITV---KDKKFRKLSKEEIEKFL 234
+EA++LA+ L KTM+ S +E +E+A + + K K+ S E + K L
Sbjct: 185 REEAVELALKVLTKTMDSTSLTSEKLELAEVYLTPSKTVKYHVHSPESLTKLL 237
>gb|AAC35982.1| (AF088914) proteasome alpha subunit [Petunia x hybrida]
Length = 249
Score = 203 bits (512), Expect = 1e-51
Identities = 101/232 (43%), Positives = 158/232 (67%), Gaps = 7/232 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA EA+ +A+G+ KDGVVL EK++TS+L++ S EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGISSKDGVVLVGEKKVTSKLLQTSTSSEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+++IDDH+A A +GI++DA +L+N AR++AQ + +Y EP P+ +V+ +CD KQ +TQY
Sbjct: 65 MYKIDDHVACAVAGIMSDANILINTARVQAQRYTFSYQEPMPVEQLVQSLCDTKQGYTQY 124
Query: 129 GGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+ PFG + L AG N +L+ +DPSG Y WKA AIG+ A ++ + Y+DD+T
Sbjct: 125 GGLPPFGVSFLFAGWDKNFGFQLFMSDPSGNYAGWKAAAIGANNQAAQSMLKQDYKDDIT 184
Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITVKD--KKFRKLSKEEIEKFL 234
+EA++LA+ L+KTM+ S +E +E+A + + + K++ S E++ L
Sbjct: 185 REEAVQLALKVLSKTMDSTSLTSEKLELAEVFLSNGKVKYQACSPEKLNSML 236
>emb|CAA73624.1| (Y13181) multicatalytic endopeptidase [Arabidopsis thaliana]
Length = 250
Score = 202 bits (508), Expect = 4e-51
Identities = 102/233 (43%), Positives = 154/233 (65%), Gaps = 8/233 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV Y EA+ +A+G+ KDGVVL EK++TS+L++ S EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYVMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+++IDDH+A A +GI++DA +L+N AR++AQ + Y EP P+ +V+ +CD KQ +TQ+
Sbjct: 65 MYKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQF 124
Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+RPFG + L AG + +LY +DPSG Y WKA A+G+ A +I + Y+DD T
Sbjct: 125 GGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYKDDAT 184
Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITV---KDKKFRKLSKEEIEKFL 234
+EA++LA+ L KTM+ S +E +E+A + + K K+ S E + K L
Sbjct: 185 REEAVELALKVLTKTMDSTSLTSEKLELAEVYLTPSKTVKYHVHSPESLTKLL 237
>sp|P34120|PRC6_DICDI PROTEASOME SUBUNIT DD5 (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
SUBUNIT DD5) >gi|347511|gb|AAA33234.1| (L22213)
proteasome [Dictyostelium discoideum]
Length = 250
Score = 201 bits (507), Expect = 5e-51
Identities = 113/246 (45%), Positives = 161/246 (64%), Gaps = 5/246 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
A YDRAITVFSPDG LFQV YA EAV++G AVGV+ KD +VL VEK+ T++L + S
Sbjct: 4 ARYDRAITVFSPDGHLFQVEYAMEAVRKGTVAVGVRGKDVIVLGVEKKATAKLQDARSIR 63
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI ++DDHI +G+ AD+RVL+++A +E Q +RLT + + I K I ++Q +TQ
Sbjct: 64 KIVKLDDHICLTFAGLTADSRVLISKALMECQSYRLTVEDSPSVEYISKFIAGIQQRYTQ 123
Query: 128 YGGVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
GGVRPFG + L+ G + P LY+TDPSG+Y +WKA AIG + E Y D+
Sbjct: 124 SGGVRPFGISTLIVGFDTDGTPNLYQTDPSGSYSSWKAAAIGRSSKSVGEFLEKNY-TDV 182
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
+ +E+IKLA+ AL + +E + +NIE+AVI K + L ++EI+K + V E E ++
Sbjct: 183 SEEESIKLAVRALLEIVESGN-KNIEIAVIRNK-QPIVLLDEQEIDKLVAVVEAEKEIQK 240
Query: 246 VKEKEE 251
+EK E
Sbjct: 241 EQEKSE 246
>pir||T48679 proteasome alpha-2 chain [validated] - Haloferax volcanii
>gi|5833208|gb|AAD53405.1|AF126261_1 (AF126261) alpha-2
subunit of 20S proteasome [Haloferax volcanii]
Length = 249
Score = 201 bits (506), Expect = 7e-51
Identities = 109/243 (44%), Positives = 152/243 (61%), Gaps = 3/243 (1%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR ++FSPDGR++QV YAREAVKRGA +GV+ DGVVLA + S L+E ES EK+
Sbjct: 9 YDRGTSLFSPDGRIYQVEYAREAVKRGAPVLGVRTADGVVLAALRSTPSELMEAESIEKL 68
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
++DD + AA++G +ADAR LV+ AR AQ L YGEP + + K I D Q TQ G
Sbjct: 69 HKLDDALGAATAGHVADARKLVDFARTTAQREHLRYGEPIGVETLTKTITDNIQESTQSG 128
Query: 130 GVRPFGAALLMAGV-NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
G RP+GA+LL+ GV N L+ TDPSG WKAVAIG R A ED Y +D++L+
Sbjct: 129 GTRPYGASLLIGGVENGSGRLFATDPSGTPQEWKAVAIGGHREDVQAALEDGYAEDLSLE 188
Query: 189 EAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVKE 248
+ + LA+ AL E+ E+ E+ ++TV + + + +E I + + + E +E E
Sbjct: 189 DGLALAVEALVAADEE--IESDELNLVTVSEAGYEIVDEETIAELFADATADDESDETDE 246
Query: 249 KEE 251
+EE
Sbjct: 247 REE 249
>gb|AAC32061.1| (AF043525) 20S proteasome subunit PAE2 [Arabidopsis thaliana]
>gi|9279577|dbj|BAB01035.1| (AB022220) 20S proteasome
subunit PAE-like protein [Arabidopsis thaliana]
Length = 237
Score = 199 bits (501), Expect = 3e-50
Identities = 106/211 (50%), Positives = 141/211 (66%), Gaps = 5/211 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+GVK K+GVVLAVEKRITS L+EP S EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKEGVVLAVEKRITSPLLEPSSVEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH---T 126
+IDDHI A SG+IADAR LV AR+E Q HR +YGEP + + +CDL
Sbjct: 68 MEIDDHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGE 127
Query: 127 QYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
+ RPFG +LL+AG ++ P LY TDPSG ++ A AIGSG A + ++++ D+
Sbjct: 128 EESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQFNKDI 187
Query: 186 TLDEAIKLAIFALAKTM-EKPSAENIEVAVI 215
TL EA +A+ L + M EK + N+++A +
Sbjct: 188 TLQEAETIAVSILKQVMEEKVTPNNVDIAKV 218
>dbj|BAA95822.1| (AP002069) ESTs AU058081(E3082),AU075427(E30384) correspond to a
region of the predicted gene.~Similar to Spinacia
oleracea proteasome 27 kD subunit (P52427) [Oryza
sativa] >gi|8096329|dbj|BAA95832.1| (AP002069) ESTs
AU058081(E3082),AU075427(E30384) correspond to a region
of the predicted gene.~Similar to Spinacia oleracea
proteasome 27 kD subunit (P52427) [Oryza sativa]
>gi|8671496|dbj|BAA96831.1| (AB026560) alpha 3 subunit
of 20S proteasome [Oryza sativa]
Length = 250
Score = 199 bits (501), Expect = 3e-50
Identities = 103/236 (43%), Positives = 157/236 (65%), Gaps = 9/236 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA EA+ +A+GV DGVVL EK++TS+L++ S EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGNAGSALGVLAADGVVLVGEKKVTSKLLQTSRSAEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+++ID H+A A +GI++DA +L+N ARL AQ + L+Y EP P+ +V+ +CD KQ +TQ+
Sbjct: 65 MYKIDSHLACAVAGIMSDANILLNTARLHAQRYALSYQEPIPVEQLVQSLCDTKQGYTQF 124
Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+RPFG + L AG + +LY +DPSG Y WKA A+G+ A ++ + YRD MT
Sbjct: 125 GGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYSGWKAAAVGANSQAAQSMLKQDYRDGMT 184
Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITVK----DKKFRKLSKEEIEKFLGE 236
+EA+ LA+ L+KTM+ S AE +E+A + ++ + +++ S E + K L +
Sbjct: 185 REEAVALALKVLSKTMDSTSLTAEKLELAEVFLQPGTGEVQYQVCSPEAMGKLLAK 240
>gb|AAD31877.1|AF140353_1 (AF140353) 20S proteasome alpha 5 subunit [Trypanosoma brucei
brucei]
Length = 246
Score = 199 bits (500), Expect = 3e-50
Identities = 98/238 (41%), Positives = 151/238 (63%), Gaps = 7/238 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GR+FQ+ YA EA+K G+T++G++ D V++A EKR+ S L++P S KI
Sbjct: 8 YDRGVNTFSPEGRIFQIEYAIEAIKLGSTSLGIQTPDAVIIAAEKRVPSTLVDPSSVNKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI SG++ADAR+LV+ AR+EAQ HR TY EP + CDL + G
Sbjct: 68 LEIDHHIGTVLSGMVADARILVDHARVEAQNHRFTYDEPMSVESCALATCDLSVQFGESG 127
Query: 130 G-----VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD 183
G RPFG +LL+AGV++ P+L++TDPSG Y + A AIG G A +F ++Y
Sbjct: 128 GRKKLMSRPFGVSLLIAGVDENGPQLWQTDPSGTYTRYDAQAIGGGAEAAQTVFSERYHR 187
Query: 184 DMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
+MT++EA L + L + M EK + ++E+A++ V + + +E+I++ + +E
Sbjct: 188 NMTVEEAENLTVQILRQVMEEKLTKTSVEIAIVPVSTGRLQIYDQEQIQRIIDRQAEE 245
>dbj|BAA96832.1| (AB026561) alpha 5 subunit of 20S proteasome [Oryza sativa]
Length = 237
Score = 199 bits (500), Expect = 3e-50
Identities = 105/212 (49%), Positives = 142/212 (66%), Gaps = 5/212 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+G+K KDGVVLAVEKR+TS L+EP S EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGLKTKDGVVLAVEKRVTSPLLEPSSVEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH---T 126
+ID+HI A SG+IADAR LV AR+E Q HR +YGEP + + ICDL
Sbjct: 68 MEIDEHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQAICDLALRFGEGD 127
Query: 127 QYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
+ RPFG +LL+AG ++ P LY TDPSG ++ A AIGSG A + +++Y ++
Sbjct: 128 EESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQYNKEL 187
Query: 186 TLDEAIKLAIFALAKTM-EKPSAENIEVAVIT 216
TL EA +A+ L + M EK + N+++A ++
Sbjct: 188 TLQEAETIALSILKQVMEEKVTPNNVDIAKVS 219
>gb|AAF89684.1|AF169652_1 (AF169652) 20S proteasome alpha 4 subunit [Trypanosoma brucei]
Length = 247
Score = 198 bits (499), Expect = 4e-50
Identities = 108/248 (43%), Positives = 159/248 (63%), Gaps = 8/248 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRAITVFSPDG LFQV YA+EAV++G AVGVK KD ++ AVEK+ +L + + KI
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVRKGLCAVGVKGKDSIIFAVEKKSVQKLQDSRTTRKI 62
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+++D+HI AS+G+ ADARV+VN A+LE Q RL+Y + + ++V+ + ++Q TQ
Sbjct: 63 YKLDEHIYLASAGLSADARVVVNHAQLECQRFRLSYEDAIDVDLLVRYVARVQQRSTQSS 122
Query: 130 GVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
G RP+G + ++ G N+ +P+L++T+PSG AW A AIG + E Y+D MT
Sbjct: 123 GSRPYGVSTIIGGFNENGQPQLWKTEPSGTSSAWNAAAIGRNDKVVLEFMEKNYQDGMTR 182
Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
D + AI AL + +E S +NIE+ V+ + K +S E+ +F+ EV KE EEE +
Sbjct: 183 DRCVHFAIKALLEAVESGS-KNIELLVL--ERGKAAYMSDTELHRFVVEVEKEREEEAAR 239
Query: 248 EK---EED 252
+ EED
Sbjct: 240 RRRLAEED 247
>gb|AAC32060.1| (AF043524) 20S proteasome subunit PAE1 [Arabidopsis thaliana]
>gi|6056394|gb|AAF02858.1|AC009324_7 (AC009324) 20S
proteasome subunit PAE1 [Arabidopsis thaliana]
Length = 237
Score = 198 bits (498), Expect = 6e-50
Identities = 105/211 (49%), Positives = 141/211 (66%), Gaps = 5/211 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+GVK K+GVVLAVEKRITS L+EP S EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKEGVVLAVEKRITSPLLEPSSVEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH---T 126
+IDDHI A SG+IADAR LV AR+E Q HR +YGEP + + +CDL
Sbjct: 68 MEIDDHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGE 127
Query: 127 QYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
+ RPFG +LL+AG ++ P LY TDPSG ++ A AIGSG A + ++++ D+
Sbjct: 128 EESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQFNKDL 187
Query: 186 TLDEAIKLAIFALAKTM-EKPSAENIEVAVI 215
+L EA +A+ L + M EK + N+++A +
Sbjct: 188 SLQEAETIAVSILKQVMEEKVTPNNVDIAKV 218
>dbj|BAA78755.1| (AB023482) ESTs AU058081(E30812),AU058365(E50679), AU030138(E50679)
correspond to a region of the predicted gene.; Similar
to Spinacia oleracea mRNA for proteasome 37kD
subunit.(X96974) [Oryza sativa]
Length = 250
Score = 198 bits (498), Expect = 6e-50
Identities = 102/236 (43%), Positives = 157/236 (66%), Gaps = 9/236 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA EA+ +A+GV DGVVL EK++TS+L++ S EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGNAGSALGVLAADGVVLVGEKKVTSKLLQTSRSAEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+++ID H+A A +GI++DA +L+N ARL AQ + L+Y EP P+ +V+ +CD KQ +TQ+
Sbjct: 65 MYKIDSHLACAVAGIMSDANILLNTARLHAQRYALSYQEPIPVEQLVQSLCDTKQGYTQF 124
Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+RPFG + L AG + +LY +DPSG Y WKA A+G+ A ++ + YRD +T
Sbjct: 125 GGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYSGWKAAAVGANSQAAQSMLKQDYRDGLT 184
Query: 187 LDEAIKLAIFALAKTMEKPS--AENIEVAVITVK----DKKFRKLSKEEIEKFLGE 236
+EA+ LA+ L+KTM+ S AE +E+A + ++ + +++ S E + K L +
Sbjct: 185 REEAVALALKVLSKTMDSTSLTAEKLELAEVFLQPGTGEVQYQVCSPEAMGKLLAK 240
>pir||T19775 hypothetical protein C36B1.4 - Caenorhabditis elegans
>gi|3874776|emb|CAB02269.1| (Z80215) contains similarity
to Pfam domain: PF00227 (Proteasome A-type and B-type),
Score=181.5, E-value=4.3e-51, N=1~cDNA EST EMBL:M79843
comes from this gene~cDNA EST yk89g4.5 comes from this
gene~cDNA EST yk361a1.3 comes from this gene~cDNA EST
yk3>
Length = 253
Score = 198 bits (497), Expect = 8e-50
Identities = 115/249 (46%), Positives = 163/249 (65%), Gaps = 11/249 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRAIT+FSPDG LFQV YA+EAVK+G+TAVGV+ KD +V+ VEK+ L + + KI
Sbjct: 4 YDRAITIFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDCIVIGVEKKSIPALQDDRTIRKI 63
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
IDDH+ A +G+ ADARVLV+RAR+E Q ++LT +P +A I + I + KQ TQ
Sbjct: 64 HMIDDHVMLAFAGLSADARVLVDRARIECQSYKLTLEDPVTVAYISRYIANTKQRFTQSP 123
Query: 130 GVRPFGAALLMAGV--NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
G RPFG ++L+ G + P L++T+PSGAY+ + A A G G E++Y ++ T+
Sbjct: 124 GRRPFGISMLIGGFDHDGTPRLFKTEPSGAYYEYVANATGRGEKPVREYLEEQYSEENTV 183
Query: 188 DEA--IKLAIFALAKTMEKPSAENIEVAVI-TVKDK-KFRKLSKEEIEKFLGEVMKEVEE 243
DEA +KL + +LA+ + P ++NIE+AV+ V D+ + R LS EEIE L K VE
Sbjct: 184 DEATTLKLVVKSLAQVV-PPGSQNIEIAVMKKVNDELQQRVLSTEEIEALL----KVVET 238
Query: 244 EEVKEKEED 252
E V + E+
Sbjct: 239 ERVAAEAEE 247
>gb|AAF34770.1|AF227625_1 (AF227625) proteasome 27 kDa subunit [Euphorbia esula]
Length = 242
Score = 197 bits (496), Expect = 1e-49
Identities = 99/228 (43%), Positives = 152/228 (66%), Gaps = 8/228 (3%)
Query: 15 TVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEKIFQID 73
T+FSP+GRL+QV YA EA+ TA+G+ KDGVVL EK++TS+L++ S EK+++ID
Sbjct: 2 TIFSPEGRLYQVEYAMEAIGNAGTAIGILSKDGVVLVGEKKVTSKLLQTSTSTEKMYKID 61
Query: 74 DHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRP 133
DH++ A +GI++DA +L+N AR++AQ + +Y EP P+ +V+ +CD KQ +TQ+GG+RP
Sbjct: 62 DHVSCAVAGIMSDANILINTARVQAQRYYFSYQEPMPVEQLVQSLCDTKQGYTQFGGLRP 121
Query: 134 FGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAI 191
FG + + AG N +LY +DPSG Y WKA AIG+ A + + Y+D++T +EA+
Sbjct: 122 FGVSFIFAGWDKNFGFQLYTSDPSGNYGGWKAAAIGANNQAAQFMLKQDYKDEITREEAV 181
Query: 192 KLAIFALAKTMEKPS-----AENIEVAVITVKDKKFRKLSKEEIEKFL 234
+LA+ L+KTM+ S E EV ++ K++ S E + K L
Sbjct: 182 QLALKVLSKTMDSTSLTSDKLELAEVFLLPSGKVKYQVCSPETVSKLL 229
>gi|6321574 proteasome component Y13; Pre9p [Saccharomyces cerevisiae]
>gi|130875|sp|P23638|PRC9_YEAST PROTEASOME COMPONENT Y13
(MACROPAIN SUBUNIT Y13) (PROTEINASE YSCE SUBUNIT 13)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT Y13)
>gi|67722|pir||SNBYY3 multicatalytic endopeptidase
complex (EC 3.4.99.46) chain Y13 - yeast (Saccharomyces
cerevisiae) >gi|172262|gb|AAA34907.1| (M63851)
proteasome Y13 [Saccharomyces cerevisiae]
>gi|506480|emb|CAA40054.1| (X56730) proteasome Y13
subunit [Saccharomyces cerevisiae]
>gi|1323225|emb|CAA97148.1| (Z72920) ORF YGR135w
[Saccharomyces cerevisiae]
Length = 258
Score = 196 bits (492), Expect = 3e-49
Identities = 97/250 (38%), Positives = 166/250 (65%), Gaps = 11/250 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA E++ TA+G+ DG+VLA E+++TS L+E + S EK
Sbjct: 6 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+++++D IA A +G+ ADA +L+N AR+ AQ + TY E P+ ++V+++ D+KQ +TQ+
Sbjct: 66 LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125
Query: 129 GGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+RPFG + + AG +D+ +LY ++PSG Y WKA+++G+ + A + + Y+DDM
Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMK 185
Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVK-----DKKFRKLSK-EEIEKFLGE--VM 238
+D+AI+LA+ L+KT + + + T++ + ++K+ K +EI+ L + +
Sbjct: 186 VDDAIELALKTLSKTTDSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIKDILVKTGIT 245
Query: 239 KEVEEEEVKE 248
K+ E+EE E
Sbjct: 246 KKDEDEEADE 255
>gi|6324535 alpha-type of subunit of 20S proteasome; Pre6p [Saccharomyces
cerevisiae] >gi|730374|sp|P40303|PRC6_YEAST PROTEASOME
COMPONENT PRE6 (MACROPAIN SUBUNIT PRE6) (PROTEINASE YSCE
SUBUNIT PRE6) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
SUBUNIT PRE6) >gi|2118150|pir||B55904 multicatalytic
endopeptidase complex (EC 3.4.99.46) chain PRE6 - yeast
(Saccharomyces cerevisiae) >gi|511905|gb|AAA34903.1|
(L34348) proteasome alpha-subunit [Saccharomyces
cerevisiae] >gi|1419833|emb|CAA99040.1| (Z74780) ORF
YOL038w [Saccharomyces cerevisiae]
Length = 254
Score = 195 bits (490), Expect = 5e-49
Identities = 102/251 (40%), Positives = 163/251 (64%), Gaps = 9/251 (3%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SY 66
+GYDRA+++FSPDG +FQV YA EAVKRG AVGVK K+ VVL E+R T +L + +
Sbjct: 2 SGYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITP 61
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
K+ +ID H+ + SG+ AD+R+L+ +AR+EAQ HRLT +P + + + + ++Q +T
Sbjct: 62 SKVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYT 121
Query: 127 QYGGVRPFGAALLMAGV---NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DK 180
Q GGVRPFG + L+AG +D+P+LY+T+PSG Y +W A IG T E D+
Sbjct: 122 QSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDR 181
Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
T++E +KL + +L + ++ A+NIE+ V+ D LS EEI +++ ++ +E
Sbjct: 182 KEPPATVEECVKLTVRSLLEVVQ-TGAKNIEITVVK-PDSDIVALSSEEINQYVTQIEQE 239
Query: 241 VEEEEVKEKEE 251
+E++ ++K++
Sbjct: 240 KQEQQEQDKKK 250
>gb|AAF70292.1|AF255338_1 (AF255338) 20S proteasome subunit [Glycine max]
Length = 237
Score = 195 bits (490), Expect = 5e-49
Identities = 103/211 (48%), Positives = 140/211 (65%), Gaps = 5/211 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+G+K K+GVVLAVEKRITS L+EP S EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGLKTKEGVVLAVEKRITSPLLEPSSVEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH---T 126
+ID+HI A SG+IADAR LV AR+E Q HR +YGEP + + +CDL
Sbjct: 68 MEIDEHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGD 127
Query: 127 QYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
+ RPFG +LL+AG ++ P LY TDPSG ++ AIGSG A + ++++ D+
Sbjct: 128 EESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNGKAIGSGSEGADSSLQEQFNKDL 187
Query: 186 TLDEAIKLAIFALAKTM-EKPSAENIEVAVI 215
TL EA +A+ L + M EK + N+++A +
Sbjct: 188 TLQEAETIALSILKQVMEEKVTPNNVDIAKV 218
>pir||T38639 proteasome component PUP2 homolog - fission yeast
(Schizosaccharomyces pombe) >gi|5777696|emb|CAB53405.1|
(AL109988) proteasome component PUP2 homolog
[Schizosaccharomyces pombe]
Length = 247
Score = 192 bits (484), Expect = 3e-48
Identities = 103/220 (46%), Positives = 143/220 (64%), Gaps = 14/220 (6%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+GVK KD VVL VEKR+TS L+E S EK+
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKDAVVLGVEKRLTSPLMESHSVEKL 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
F+ID HI A SG+ ADAR ++ AR++ Q HR TY EP + + ICDL ++G
Sbjct: 68 FEIDSHIGCAISGLTADARTIIEHARVQTQNHRFTYDEPQGIESTTQSICDLA---LRFG 124
Query: 130 G---------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFED 179
RPFG ALL+AG+++ P+LY ++PSG YF ++A AIGSG A +
Sbjct: 125 EGEDGEERIMSRPFGVALLIAGIDEHGPQLYHSEPSGTYFRYEAKAIGSGSEPAKSELVK 184
Query: 180 KYRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVK 218
++ DMTL+EA L + L + M EK ++N+++A +T +
Sbjct: 185 EFHKDMTLEEAEVLILKVLRQVMEEKLDSKNVQLAKVTAE 224
>pdb|1G65|B Chain B, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
Molecular Basis For Selectivity Of
Alpha,Beta-Epoxyketone Proteasome Inhibitors
>gi|11513428|pdb|1G65|P Chain P, Crystal Structure Of
Epoxomicin:20s Proteasome Reveals A Molecular Basis For
Selectivity Of Alpha,Beta-Epoxyketone Proteasome
Inhibitors >gi|3114271|pdb|1RYP|C Chain C, Crystal
Structure Of The 20s Proteasome From Yeast At 2.4
Angstroms Resolution >gi|3114285|pdb|1RYP|Q Chain Q,
Crystal Structure Of The 20s Proteasome From Yeast At
2.4 Angstroms Resolution
Length = 244
Score = 192 bits (483), Expect = 3e-48
Identities = 89/211 (42%), Positives = 147/211 (69%), Gaps = 5/211 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA E++ TA+G+ DG+VLA E+++TS L+E + S EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+++++D IA A +G+ ADA +L+N AR+ AQ + TY E P+ ++V+++ D+KQ +TQ+
Sbjct: 65 LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 124
Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+RPFG + + AG +D+ +LY ++PSG Y WKA+++G+ + A + + Y+DDM
Sbjct: 125 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMK 184
Query: 187 LDEAIKLAIFALAKTMEKPSA--ENIEVAVI 215
+D+AI+LA+ L+KT + + + +E A I
Sbjct: 185 VDDAIELALKTLSKTTDSSALTYDRLEFATI 215
>pdb|1G0U|B Chain B, A Gated Channel Into The Proteasome Core Particle
>gi|11514007|pdb|1G0U|P Chain P, A Gated Channel Into
The Proteasome Core Particle
Length = 245
Score = 192 bits (483), Expect = 3e-48
Identities = 89/211 (42%), Positives = 147/211 (69%), Gaps = 5/211 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA E++ TA+G+ DG+VLA E+++TS L+E + S EK
Sbjct: 6 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+++++D IA A +G+ ADA +L+N AR+ AQ + TY E P+ ++V+++ D+KQ +TQ+
Sbjct: 66 LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125
Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+RPFG + + AG +D+ +LY ++PSG Y WKA+++G+ + A + + Y+DDM
Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMK 185
Query: 187 LDEAIKLAIFALAKTMEKPSA--ENIEVAVI 215
+D+AI+LA+ L+KT + + + +E A I
Sbjct: 186 VDDAIELALKTLSKTTDSSALTYDRLEFATI 216
>sp|Q10329|PRC6_SCHPO PUTATIVE PROTEASOME COMPONENT PRE6 (MACROPAIN SUBUNIT)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT)
>gi|7492853|pir||T37985 proteasome component SPBC106.16
- fission yeast (Schizosaccharomyces pombe)
>gi|7493192|pir||T39273 proteasome component SPBC106.16
- fission yeast (Schizosaccharomyces pombe)
>gi|1216254|emb|CAA93796.1| (Z69909) putative proteasome
component [Schizosaccharomyces pombe]
>gi|5817282|emb|CAB53732.1| (AL110295) proteasome
component; PROS28 family [Schizosaccharomyces pombe]
Length = 259
Score = 191 bits (480), Expect = 8e-48
Identities = 95/246 (38%), Positives = 160/246 (64%), Gaps = 7/246 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
+GYDRA++VFSPDGRL QV Y +EAV+RG TA+ ++ + +V+ VE++ +L +++
Sbjct: 2 SGYDRALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQ 61
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
KI +D+H+ A +G+ ADAR+L+++AR+EAQ H+L +P + + + + ++Q +TQ
Sbjct: 62 KIAMVDNHVCLAFAGLNADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYTQ 121
Query: 128 YGGVRPFGAALLMAGV---NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
GGVRPFG + L+AG ++ P +Y+T+P+G Y AWKA AIG A E +++
Sbjct: 122 SGGVRPFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNWKEG 181
Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITV-KDKKFRKLSKEEIEKFLGEVMKEVEE 243
++ DE I LA+ +L + ++ S NIE+A++ KD +F L ++I+ + E+ E E
Sbjct: 182 LSRDETIHLAVSSLLEVVQTASG-NIELAIMDPGKDVEF--LHSDKIDTIVKEIQDEKEA 238
Query: 244 EEVKEK 249
E ++K
Sbjct: 239 EAARKK 244
>pdb|1G0U|C Chain C, A Gated Channel Into The Proteasome Core Particle
>gi|11514008|pdb|1G0U|Q Chain Q, A Gated Channel Into
The Proteasome Core Particle
Length = 243
Score = 191 bits (480), Expect = 8e-48
Identities = 101/244 (41%), Positives = 157/244 (63%), Gaps = 9/244 (3%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SY 66
+GYDRA+++FSPDG +FQV YA EAVKRG AVGVK K+ VVL E+R T +L + +
Sbjct: 2 SGYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITP 61
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
K+ +ID H+ + SG+ AD+R+L+ +AR+EAQ HRLT +P + + + + ++Q +T
Sbjct: 62 SKVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYT 121
Query: 127 QYGGVRPFGAALLMAGV---NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DK 180
Q GGVRPFG + L+AG +D+P+LY+T+PSG Y +W A IG T E D+
Sbjct: 122 QSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDR 181
Query: 181 YRDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
T++E +KL + +L + ++ A+NIE+ V+ D LS EEI +++ ++ +E
Sbjct: 182 KEPPATVEECVKLTVRSLLEVVQ-TGAKNIEITVVK-PDSDIVALSSEEINQYVTQIEQE 239
Query: 241 VEEE 244
+E+
Sbjct: 240 KQEQ 243
>pdb|1G65|C Chain C, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
Molecular Basis For Selectivity Of
Alpha,Beta-Epoxyketone Proteasome Inhibitors
>gi|11513429|pdb|1G65|Q Chain Q, Crystal Structure Of
Epoxomicin:20s Proteasome Reveals A Molecular Basis For
Selectivity Of Alpha,Beta-Epoxyketone Proteasome
Inhibitors >gi|3114272|pdb|1RYP|D Chain D, Crystal
Structure Of The 20s Proteasome From Yeast At 2.4
Angstroms Resolution >gi|3114286|pdb|1RYP|R Chain R,
Crystal Structure Of The 20s Proteasome From Yeast At
2.4 Angstroms Resolution
Length = 241
Score = 190 bits (479), Expect = 1e-47
Identities = 101/243 (41%), Positives = 156/243 (63%), Gaps = 9/243 (3%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYE 67
GYDRA+++FSPDG +FQV YA EAVKRG AVGVK K+ VVL E+R T +L + +
Sbjct: 1 GYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPS 60
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
K+ +ID H+ + SG+ AD+R+L+ +AR+EAQ HRLT +P + + + + ++Q +TQ
Sbjct: 61 KVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQ 120
Query: 128 YGGVRPFGAALLMAGV---NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DKY 181
GGVRPFG + L+AG +D+P+LY+T+PSG Y +W A IG T E D+
Sbjct: 121 SGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRK 180
Query: 182 RDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEV 241
T++E +KL + +L + ++ A+NIE+ V+ D LS EEI +++ ++ +E
Sbjct: 181 EPPATVEECVKLTVRSLLEVVQ-TGAKNIEITVVK-PDSDIVALSSEEINQYVTQIEQEK 238
Query: 242 EEE 244
+E+
Sbjct: 239 QEQ 241
>sp|Q09682|PRC9_SCHPO PUTATIVE PROTEASOME COMPONENT C9/Y13 (MACROPAIN SUBUNIT)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT)
>gi|2118147|pir||S58093 probable multicatalytic
endopeptidase complex (EC 3.4.99.46) chain SPA13C5.01c -
fission yeast (Schizosaccharomyces pombe)
>gi|908890|emb|CAA90452.1| (Z50112) proteasome component
y13 [Schizosaccharomyces pombe]
Length = 248
Score = 190 bits (477), Expect = 2e-47
Identities = 98/241 (40%), Positives = 153/241 (62%), Gaps = 5/241 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA EA+ A+G+ KDG+VLA EK++TS+L+E E S EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYALEAINHAGVALGIVAKDGIVLAAEKKVTSKLLEQEESAEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
++ I D++ A +G+ ADA +L+N AR Q + T+ E P +V+++CDLKQ +TQY
Sbjct: 65 LYHIGDNMLCAVAGLTADANILINYARRVGQQYLQTFNEEMPCEQLVRRVCDLKQGYTQY 124
Query: 129 GGVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG+RPFG + L AG + +L++++PSG Y +W+A +IG + ++ +Y+DD+
Sbjct: 125 GGLRPFGVSFLYAGWDHIRGYQLFQSNPSGNYGSWQANSIGGNSTSVQSLMRQEYKDDIN 184
Query: 187 LDEAIKLAIFALAKTMEKPSA--ENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
LDEA +A+ L+KT++ S E IE A IT K + + K + EV+ + +E
Sbjct: 185 LDEASAMAVKFLSKTLDSNSLTHEKIEFATITKDTTKNKMVCKIWKSDEINEVLNKYQET 244
Query: 245 E 245
+
Sbjct: 245 Q 245
>gi|4506185 proteasome (prosome, macropain) subunit, alpha type, 4 [Homo
sapiens] >gi|11431712|ref|XP_007578.1| proteasome
(prosome, macropain) subunit, alpha type, 4 [Homo
sapiens] >gi|130861|sp|P25789|PRC9_HUMAN PROTEASOME
COMPONENT C9 (MACROPAIN SUBUNIT C9) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C9) >gi|67720|pir||SNHUC9
multicatalytic endopeptidase complex (EC 3.4.99.46)
chain C9 - human >gi|220030|dbj|BAA00660.1| (D00763)
proteasome subunit C9 [Homo sapiens]
Length = 261
Score = 189 bits (476), Expect = 2e-47
Identities = 106/257 (41%), Positives = 164/257 (63%), Gaps = 10/257 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
YD T+FSP+GRL+QV YA EA+ T +G+ DGV+LA E+R +L++ + EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I+++++ +A + +GI +DA VL N RL AQ + L Y EP P +V +CD+KQ +TQ+
Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
Query: 129 GGVRPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-D 184
GG RPFG +LL G DK +LY++DPSG Y WKA IG+ A+++ + Y++ +
Sbjct: 125 GGKRPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGE 183
Query: 185 MTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMKE 240
MTL A+ LAI L KTM+ K SAE +E+A +T ++ K R L ++E+E+ + + +E
Sbjct: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEE 243
Query: 241 VEEEEVKEKEEDYSELD 257
+ E ++KE++ E D
Sbjct: 244 EAKAEREKKEKEQKEKD 260
>pir||S17521 multicatalytic endopeptidase complex (EC 3.4.99.46) zeta chain -
human
Length = 241
Score = 189 bits (475), Expect = 3e-47
Identities = 106/238 (44%), Positives = 149/238 (62%), Gaps = 14/238 (5%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+G++ +GV LAVEKRITS L+EP S EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI A SG+IADA+ L+++AR+E Q H TY E + + + + +L Q+G
Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124
Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
RPFG ALL GV++K P+L+ DPSG + A AIGS A + ++
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEL 184
Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
Y MTL EAIK ++ L + M EK +A NIE+A + + F +KEE+E+ + ++
Sbjct: 185 YHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241
>gi|7106387 proteasome (prosome, macropain) subunit, alpha type 5 [Mus
musculus] >gi|3805976|gb|AAC69149.1| (AF019661) zeta
proteasome chain; PSMA5 [Mus musculus]
Length = 241
Score = 189 bits (475), Expect = 3e-47
Identities = 106/238 (44%), Positives = 149/238 (62%), Gaps = 14/238 (5%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+G++ +GV LAVEKRITS L+EP S EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI A SG+IADA+ L+++AR+E Q H TY E + + + + +L Q+G
Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124
Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
RPFG ALL GV++K P+L+ DPSG + A AIGS A + ++
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEV 184
Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
Y MTL EAIK ++ L + M EK +A NIE+A + + F +KEE+E+ + ++
Sbjct: 185 YHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241
>gi|8394069 proteasome (prosome, macropain) subunit, alpha type 4 [Rattus
norvegicus] >gi|130862|sp|P21670|PRC9_RAT PROTEASOME
COMPONENT C9 (MACROPAIN SUBUNIT C9) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C9) (PROTEASOME SUBUNIT L)
>gi|67721|pir||SNRTC9 multicatalytic endopeptidase
complex (EC 3.4.99.46) chain C9 - rat
>gi|56641|emb|CAA39458.1| (X55986) multicatalytic
proteinase subunit L [Rattus rattus]
>gi|57000|emb|CAA37390.1| (X53304) unnamed protein
product [Rattus norvegicus]
Length = 261
Score = 189 bits (474), Expect = 4e-47
Identities = 105/257 (40%), Positives = 164/257 (62%), Gaps = 10/257 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
YD T+FSP+GRL+QV YA EA+ T +G+ DGV+LA E+R +L++ + EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I+++++ +A + +GI +DA VL N RL AQ + L Y EP P +V +CD+KQ +TQ+
Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
Query: 129 GGVRPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-D 184
GG RPFG +LL G DK +LY++DPSG Y WKA IG+ A+++ + Y++ +
Sbjct: 125 GGKRPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGE 183
Query: 185 MTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMKE 240
MTL A+ LA+ L KTM+ K SAE +E+A +T ++ K R L ++E+E+ + + +E
Sbjct: 184 MTLKSALALAVKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEE 243
Query: 241 VEEEEVKEKEEDYSELD 257
+ E ++KE++ E D
Sbjct: 244 EAKAEREKKEKEQREKD 260
>gi|6755196 proteasome (prosome, macropain) subunit, alpha type 4 [Mus
musculus] >gi|9910830|sp|Q9R1P0|PRC9_MOUSE PROTEASOME
COMPONENT C9 (MACROPAIN SUBUNIT C9) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C9)
>gi|5757663|gb|AAD50538.1|AF060093_1 (AF060093)
proteasome subunit C9 [Mus musculus]
Length = 261
Score = 188 bits (473), Expect = 5e-47
Identities = 105/257 (40%), Positives = 163/257 (62%), Gaps = 10/257 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
YD T+FSP+GRL+QV YA EA+ T +G+ DGV+LA E+R +L++ + EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I+++++ +A + +GI +DA VL N RL AQ + L Y EP P +V +CD+KQ +TQ+
Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
Query: 129 GGVRPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-D 184
GG RPFG +LL G DK +LY++DPSG Y WKA IG+ A+++ + Y++ +
Sbjct: 125 GGKRPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGE 183
Query: 185 MTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMKE 240
MTL A+ LA+ L KTM+ K SAE +E+A +T + K R L ++E+E+ + + +E
Sbjct: 184 MTLKSALALAVKVLNKTMDVSKLSAEKVEIATLTRESGKTVIRVLKQKEVEQLIKKHEEE 243
Query: 241 VEEEEVKEKEEDYSELD 257
+ E ++KE++ E D
Sbjct: 244 EAKAEREKKEKEQREKD 260
>sp|Q95083|PRCZ_DROME PROTEASOME PSMA5 SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
PSMA5 CHAIN) >gi|1498589|gb|AAB93421.1| (U64721) 20S
proteasome alpha subunit PSMA5 [Drosophila melanogaster]
Length = 244
Score = 188 bits (472), Expect = 7e-47
Identities = 103/237 (43%), Positives = 147/237 (61%), Gaps = 10/237 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+G+ +GVVLAVEKRITS L+ P + EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
++D HI A+SG++ADAR L+ RAR+E Q H Y E + + + L G
Sbjct: 68 VEVDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSG 127
Query: 130 G-------VRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
RPFG A+L AG+ +P+L+ DPSG + A AIGSG A +D +
Sbjct: 128 DSDGAAAMSRPFGVAILFAGIEAGQPQLWHMDPSGTFVGHGAKAIGSGSEGAQQNLQDLF 187
Query: 182 RDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
R D+TLDEAI +++ L + M EK ++ N+EV +T K+++F +KEE+E+ + +
Sbjct: 188 RPDLTLDEAIDISLNTLKQVMEEKLNSTNVEVMTMT-KEREFYMFTKEEVEQHIKNI 243
>gb|AAF57875.1| (AE003803) ProsMA5 gene product [Drosophila melanogaster]
Length = 244
Score = 187 bits (471), Expect = 9e-47
Identities = 103/237 (43%), Positives = 147/237 (61%), Gaps = 10/237 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+G+ +GVVLAVEKRITS L+ P + EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
++D HI A+SG++ADAR L+ RAR+E Q H Y E + + + L G
Sbjct: 68 VEVDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSG 127
Query: 130 G-------VRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
RPFG A+L AG+ +P+L+ DPSG + A AIGSG A +D +
Sbjct: 128 DSDGAAAMSRPFGVAILFAGIEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLF 187
Query: 182 RDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
R D+TLDEAI +++ L + M EK ++ N+EV +T K+++F +KEE+E+ + +
Sbjct: 188 RPDLTLDEAIDISLNTLKQVMEEKLNSTNVEVMTMT-KEREFYMFTKEEVEQHIKNI 243
>sp|O73672|PRC3_CARAU PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C3) (PROTEASOME ALPHA-2
SUBUNIT) >gi|3107927|dbj|BAA25915.1| (AB013342)
proteasome alpha 2 subunit [Carassius auratus]
Length = 234
Score = 187 bits (470), Expect = 1e-46
Identities = 102/231 (44%), Positives = 144/231 (62%), Gaps = 4/231 (1%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GY ++T FSP G+L Q+ YA AV GA +VG+K +GVVLA EK+ S L + +S K
Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKASNGVVLATEKKQKSILYDEQSVHK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I I HI SG+ D RVLV RAR AQ + L Y EP P +V+++ + Q +TQ
Sbjct: 65 IEPITKHIGMVYSGMGPDYRVLVRRARKLAQQYFLVYQEPIPTGQLVQRVASVMQEYTQS 124
Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
GGVRPFG +LL+AG + D+P L+++DPSGAYFAWKA A+G E +Y +D+ L
Sbjct: 125 GGVRPFGVSLLIAGWDEDRPYLFQSDPSGAYFAWKATAMGKSYVNGKTFLEKRYNEDLEL 184
Query: 188 DEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
++AI AI L ++ E + + ENIEV + + FR+LS E++ +L +
Sbjct: 185 EDAIHTAILTLKESFEGQMTEENIEVGI--CNEAGFRRLSPAEVKDYLAAI 233
>pir||S38530 multicatalytic endopeptidase complex (EC 3.4.99.46) chain XC9
(clone 1) - clawed frog
Length = 261
Score = 187 bits (470), Expect = 1e-46
Identities = 110/261 (42%), Positives = 164/261 (62%), Gaps = 18/261 (6%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
YD T+FSP+GRL+QV YA EA+ T +G+ DGV+LA E+R +L++ + EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDDVFFSEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I++++D +A + +GI +DA VL N RL AQ + L Y EP P +V +CD+KQ +TQ+
Sbjct: 65 IYKLNDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
Query: 129 GGVRPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-D 184
GG RPFG +LL G DK +LY++DPSG Y WKA IG+ A+++ + Y++
Sbjct: 125 GGKRPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGG 183
Query: 185 MTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKD--KKFRKLSKEEIEKFLGEVMKE 240
MTL A+ LA+ L KTM+ K SAE +E+A +T ++ K R L ++E+E E++K
Sbjct: 184 MTLKSALALAVKVLNKTMDVSKLSAEKVELATLTRENGKTKIRVLQQKEVE----ELIKL 239
Query: 241 VEEEEVK----EKEEDYSELD 257
EEEE K +K+++ E D
Sbjct: 240 HEEEEAKIEREKKDKEQKEKD 260
>gi|4506187 proteasome (prosome, macropain) subunit, alpha type, 5; Proteasome
component 5 [Homo sapiens]
>gi|464456|sp|P28066|PRCZ_HUMAN PROTEASOME ZETA CHAIN
(MACROPAIN ZETA CHAIN) (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX ZETA CHAIN) >gi|296740|emb|CAA43962.1| (X61970)
macropain subunit zeta [Homo sapiens]
Length = 241
Score = 187 bits (469), Expect = 1e-46
Identities = 105/238 (44%), Positives = 148/238 (62%), Gaps = 14/238 (5%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV Y EA+K G+TA+G++ +GV LAVEKRITS L+EP S EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYDIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI A SG+IADA+ L+++AR+E Q H TY E + + + + +L Q+G
Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124
Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
RPFG ALL GV++K P+L+ DPSG + A AIGS A + ++
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEL 184
Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
Y MTL EAIK ++ L + M EK +A NIE+A + + F +KEE+E+ + ++
Sbjct: 185 YHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241
>pir||T40971 20s proteasome component C3 - fission yeast (Schizosaccharomyces
pombe) >gi|3790251|emb|CAA21440.1| (AL031966) 20s
proteasome component C3 [Schizosaccharomyces pombe]
Length = 245
Score = 186 bits (468), Expect = 2e-46
Identities = 105/241 (43%), Positives = 147/241 (60%), Gaps = 13/241 (5%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
Y ++T FSP+G+L Q+ YA AV G T+VG+K DGVVLA EK+ TS L S EK+
Sbjct: 5 YAFSLTTFSPNGKLVQIEYALNAVNAGVTSVGIKATDGVVLATEKKPTSELAIGASLEKV 64
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQ-IHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I I SG+ D RVLV+++R AQ ++ Y E P ++V++I + Q TQ
Sbjct: 65 CAITPDIGMVYSGMGPDFRVLVDKSRKVAQTTYKKIYNEYPPTKILVQEIASVMQESTQS 124
Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
GGVRPFG +LL+AG+++K P LY+ DPSG YFAWKA AIG A E +Y D++ L
Sbjct: 125 GGVRPFGVSLLVAGMDEKGPSLYQVDPSGTYFAWKATAIGKSSTAAKTFLEKRYNDELEL 184
Query: 188 DEAIKLAIFALAKTME-KPSAENIEVAVITVKDK----------KFRKLSKEEIEKFLGE 236
D+A+ AI AL +T E + + +NIE+AV++ K F +LS+ EI +L +
Sbjct: 185 DDAVHTAILALKETFEGELTEDNIEIAVVSTKPTDSGIVGVPGGHFCRLSQSEIRDYLDQ 244
Query: 237 V 237
V
Sbjct: 245 V 245
>sp|P34119|PRC9_DICDI PROTEASOME SUBUNIT DD4 (MULTICATALYTIC ENDOPEPTIDASE COMPLEX
SUBUNIT DD4) >gi|347509|gb|AAA33233.1| (L22212)
proteasome [Dictyostelium discoideum]
Length = 250
Score = 186 bits (467), Expect = 3e-46
Identities = 98/246 (39%), Positives = 156/246 (62%), Gaps = 11/246 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY--E 67
YD+ T+FSP+GR++QV YA A++ VG+ KDG+VLA EK+ T++L++ + E
Sbjct: 5 YDQRTTIFSPEGRVYQVEYAMTAIRHAGATVGILAKDGIVLAAEKKTTAKLLDSSTSISE 64
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
K+F+ID+H+ A +GI +DA +L+N ARL +Q Y EP P+ +V +ICD KQ +TQ
Sbjct: 65 KMFKIDEHVVCAVAGITSDANILINYARLSSQRFFYQYQEPMPVEQLVSQICDTKQGYTQ 124
Query: 128 YGGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNT--AMAIFEDKYRD 183
YGG+RPFG + L AG + +LY++DPSG + WKA +IG G N+ A ++ Y+
Sbjct: 125 YGGLRPFGVSFLYAGWDRHYGFQLYQSDPSGNFAGWKATSIG-GENSQVAQSVLRSNYKP 183
Query: 184 DMTLDEAIKLAIFALAKTMEKP--SAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMK 239
D++L EA++LA+ L KTM++ ++E +E + T + + + E++ F+ E
Sbjct: 184 DISLKEALQLALKVLTKTMDRSNINSEKLEFSYFTKQGDNVVYHIFTAAELDAFIKETDL 243
Query: 240 EVEEEE 245
E E E+
Sbjct: 244 EQETED 249
>sp|P22769|PRC6_DROME PROTEASOME 28 KD SUBUNIT 1 (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 28
KD SUBUNIT 1) >gi|85119|pir||JQ0681 proteasome chain 1 -
fruit fly (Drosophila melanogaster)
>gi|158186|gb|AAA62768.1| (M57712) proteasome
beta-subunit [Drosophila melanogaster]
Length = 249
Score = 185 bits (464), Expect = 6e-46
Identities = 101/246 (41%), Positives = 151/246 (61%), Gaps = 6/246 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRA+T+FSPDG L QV YA+EAV++G+TAVGV+ + VVL VEK+ ++L E KI
Sbjct: 5 YDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKI 64
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+D+H+ A +G+ ADAR+++NRA++E Q HRL +P L I + I LKQ +TQ
Sbjct: 65 CMLDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSN 124
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
G RPFG + L+ G + L++T+PSG ++ +KA A G FE YR++
Sbjct: 125 GRRPFGISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVA 184
Query: 188 DE--AIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
+E A+KLAI AL + + N+EVA++ K + L + I ++ + KE EEE
Sbjct: 185 NEHGAVKLAIRALLEVAQS-GQNNLEVAIME-NGKPLKMLDNDVITDYVKIIEKEKEEEL 242
Query: 246 VKEKEE 251
K+K++
Sbjct: 243 EKKKQK 248
>pir||S23451 multicatalytic endopeptidase complex (EC 3.4.99.46) 28K chain -
fruit fly (Drosophila melanogaster)
>gi|8386|emb|CAA44174.1| (X62286) 28 KDa proteasome
subunit [Drosophila melanogaster]
>gi|7293190|gb|AAF48573.1| (AE003501) Pros28.1 gene
product [Drosophila melanogaster]
Length = 249
Score = 184 bits (463), Expect = 7e-46
Identities = 101/246 (41%), Positives = 151/246 (61%), Gaps = 6/246 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRA+T+FSPDG L QV YA+EAV++G+TAVGV+ + VVL VEK+ ++L E KI
Sbjct: 5 YDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKI 64
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+D+H+ A +G+ ADAR+++NRA++E Q HRL +P L I + I LKQ +TQ
Sbjct: 65 CMLDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSN 124
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
G RPFG + L+ G + L++T+PSG ++ +KA A G FE YR++
Sbjct: 125 GRRPFGISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVA 184
Query: 188 DE--AIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
+E A+KLAI AL + + N+EVA++ K + L + I ++ + KE EEE
Sbjct: 185 NEHGAVKLAIRALLEVAQS-GQNNLEVAIME-NGKPLKMLDTDVITDYVKIIEKEKEEEL 242
Query: 246 VKEKEE 251
K+K++
Sbjct: 243 EKKKQK 248
>gi|4506181 proteasome (prosome, macropain) subunit, alpha type, 2 [Homo
sapiens] >gi|11421228|ref|XP_004888.1| similar to
proteasome (prosome, macropain) subunit, alpha type, 2
(H. sapiens) [Homo sapiens]
>gi|130850|sp|P25787|PRC3_HUMAN PROTEASOME COMPONENT C3
(MACROPAIN SUBUNIT C3) (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX SUBUNIT C3) >gi|67725|pir||SNHUC3 multicatalytic
endopeptidase complex (EC 3.4.99.46) chain C3 - human
>gi|220024|dbj|BAA00657.1| (D00760) proteasome subunit
C3 [Homo sapiens]
Length = 234
Score = 184 bits (463), Expect = 7e-46
Identities = 99/233 (42%), Positives = 145/233 (61%), Gaps = 4/233 (1%)
Query: 7 QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
+ GY ++T FSP G+L Q+ YA AV GA +VG+K +GVVLA EK+ S L + S
Sbjct: 3 ERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSV 62
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
K+ I HI SG+ D RVLV+RAR AQ + L Y EP P A +V+++ + Q +T
Sbjct: 63 HKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYT 122
Query: 127 QYGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
Q GGVRPFG +LL+ G N+ +P L+++DPSGAYFAWKA A+G E +Y +D+
Sbjct: 123 QSGGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDL 182
Query: 186 TLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
L++AI AI L ++ E + + +NIEV + + FR+L+ E++ +L +
Sbjct: 183 ELEDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFRRLTPTEVKDYLAAI 233
>sp|O23708|PRC3_ARATH PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C3)
>gi|2511574|emb|CAA73619.1| (Y13176) multicatalytic
endopeptidase [Arabidopsis thaliana]
>gi|3421075|gb|AAC32056.1| (AF043520) 20S proteasome
subunit PAB1 [Arabidopsis thaliana]
>gi|4966368|gb|AAD34699.1|AC006341_27 (AC006341)
Identical to gb|Y13176 Arabidopsis thaliana mRNA for
proteasome subunit prc3. ESTs gb|H36972, gb|T22551 and
gb|T13800 come from this gene
Length = 235
Score = 184 bits (463), Expect = 7e-46
Identities = 99/230 (43%), Positives = 147/230 (63%), Gaps = 3/230 (1%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
Y ++T FSP G+L Q+ +A AV G T++G+K +GVV+A EK++ S L++ S +KI
Sbjct: 6 YSFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKASNGVVIATEKKLPSILVDEASVQKI 65
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ +I SG+ D RVLV ++R +A+ + Y EP P+ +V++ + Q TQ G
Sbjct: 66 QHLTPNIGVVYSGMGPDFRVLVRKSRKQAEQYLRLYKEPIPVTQLVRETATVMQEFTQSG 125
Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
GVRPFG +LL+AG +DK P+LY+ DPSG+YF+WKA A+G + A E +Y +DM LD
Sbjct: 126 GVRPFGVSLLVAGYDDKGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMELD 185
Query: 189 EAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
+AI AI L + E + S++NIE+ I DK FR L+ EI+ +L EV
Sbjct: 186 DAIHTAILTLKEGFEGEISSKNIEIGKIGA-DKVFRVLTPAEIDDYLAEV 234
>gi|11428206 proteasome (prosome, macropain) subunit, alpha type, 5 [Homo
sapiens]
Length = 241
Score = 184 bits (463), Expect = 7e-46
Identities = 105/238 (44%), Positives = 148/238 (62%), Gaps = 14/238 (5%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EA+K G+TA+G++ +GV LAVEKRITS L+EP S EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI A SG+IADA+ L+++AR+E Q H TY E + + + + +L Q+G
Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124
Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
RPFG ALL GV++K P+L+ DPSG + A AIGS A + ++
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEL 184
Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
MTL EAIK ++ L + M EK +A NIE+A + + F +KEE+E+ + ++
Sbjct: 185 CFKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241
>gi|8394063 proteasome (prosome, macropain) subunit, alpha type 2 [Rattus
norvegicus] >gi|130851|sp|P17220|PRC3_RAT PROTEASOME
COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C3) >gi|67726|pir||SNRTC3
proteasome chain C3 - rat >gi|203203|gb|AAA40838.1|
(J02897) proteasome component C3 protein [Rattus
norvegicus] >gi|5757867|gb|AAD50623.1|AF099733_1
(AF099733) proteasome subunit C3 [Mus musculus]
Length = 234
Score = 184 bits (462), Expect = 1e-45
Identities = 99/233 (42%), Positives = 144/233 (61%), Gaps = 4/233 (1%)
Query: 7 QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
+ GY ++T FSP G+L Q+ YA AV GA +VG+K +GVVLA EK+ S L + S
Sbjct: 3 ERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSV 62
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
K+ I HI SG+ D RVLV+RAR AQ + L Y EP P A +V+++ + Q +T
Sbjct: 63 HKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYT 122
Query: 127 QYGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
Q GGVRPFG +LL+ G N+ +P L+++DPSGAYFAWKA A+G E +Y +D+
Sbjct: 123 QSGGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDL 182
Query: 186 TLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
L++AI AI L ++ E + + +NIEV + + FR+L+ E+ +L +
Sbjct: 183 ELEDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFRRLTPTEVRDYLAAI 233
>gb|AAF05906.1|AF148125_1 (AF148125) 20S proteasome alpha 2 subunit [Trypanosoma brucei
brucei]
Length = 231
Score = 184 bits (462), Expect = 1e-45
Identities = 95/226 (42%), Positives = 143/226 (63%), Gaps = 4/226 (1%)
Query: 14 ITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIFQID 73
+T FSP GRL Q+ YA A +G TA+GVK DGVV+A EK+ TS L + + K+F +D
Sbjct: 8 LTTFSPSGRLVQIEYATTAASKGTTALGVKATDGVVIAAEKKTTSPLADSLTLHKVFALD 67
Query: 74 DHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRP 133
DH+ SGI D RVLV+ AR Q +RLTY EP P++ +V++I L Q TQ GGVRP
Sbjct: 68 DHVGCTYSGIGPDCRVLVDAARRACQRYRLTYHEPMPISQLVRQISFLFQEFTQSGGVRP 127
Query: 134 FGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIK 192
FG +LL+AG + + LY+ DPSG ++ WKA +IG G A E +Y ++M +++A+
Sbjct: 128 FGCSLLVAGADSRGNHLYQLDPSGTFWTWKATSIGKGSPDARTFLEKRYTNEMEIEDAVH 187
Query: 193 LAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
A+ L + + + +AEN +V V + +F L+ E+++ +L ++
Sbjct: 188 TALLTLKEGFDGRMTAENTQVG--RVVEGRFELLTVEQLKDYLDQI 231
>emb|CAB62817.1| (AL133435) 20S proteasome alpha 2 subunit [Leishmania major]
Length = 231
Score = 184 bits (462), Expect = 1e-45
Identities = 95/226 (42%), Positives = 144/226 (63%), Gaps = 4/226 (1%)
Query: 14 ITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIFQID 73
+T FSP G+L Q+ YA A +G TA+GVK DGVV+A +K+ S L++ S +K+F +D
Sbjct: 8 LTTFSPSGKLVQIEYATTAAGKGTTALGVKATDGVVIAAKKKAPSTLVDASSIQKVFILD 67
Query: 74 DHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRP 133
+H+ SG+ D RVL++ AR Q +RL Y EP P++ +V+KI L Q TQ GGVRP
Sbjct: 68 EHVGCTYSGMGPDCRVLIDSARKNCQQYRLMYNEPIPISQLVRKISALYQEFTQSGGVRP 127
Query: 134 FGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIK 192
FG +LL+AGV+ + LY+ DPSG ++AWKA AIG+G A A E +Y DM L++A+
Sbjct: 128 FGCSLLVAGVDANGYHLYQVDPSGTFWAWKATAIGTGSPDAKAFLEKRYTVDMELEDAVH 187
Query: 193 LAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
A+ L + + + ++EN +V V +F LS +++ +L ++
Sbjct: 188 TALLTLKEGFDGQMTSENTQVG--RVVGNRFEVLSVDQLRDYLDQI 231
>gi|6679497 proteasome (prosome, macropain) subunit, alpha type 2 [Mus
musculus] >gi|1709759|sp|P49722|PRC3_MOUSE PROTEASOME
COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C3)
>gi|897784|emb|CAA49782.1| (X70303) proteasome, 25 kDa
subunit [Mus musculus]
Length = 234
Score = 183 bits (461), Expect = 1e-45
Identities = 99/231 (42%), Positives = 143/231 (61%), Gaps = 4/231 (1%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GY ++T FSP G+L Q+ YA AV GA +VG+K +GVVLA EK+ S L + S K
Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+ I HI SG+ D RVLV+RAR AQ + L Y EP P A +V+++ + Q +TQ
Sbjct: 65 VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124
Query: 129 GGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
GGVRPFG +LL+ G N+ +P L+++DPSGAYFAWKA A+G E +Y +D+ L
Sbjct: 125 GGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184
Query: 188 DEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
++AI AI L ++ E + + +NIEV + + FR+L+ E+ +L +
Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFRRLTPTEVRDYLAAI 233
>sp|P24495|PRC3_XENLA PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT C3) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C3) >gi|85841|pir||JH0421
proteasome chain XC3 - African clawed frog
>gi|233668|gb|AAB19485.1| (S51111) proteasome subunit
XC3 [Xenopus laevis, Peptide, 234 aa]
Length = 234
Score = 183 bits (460), Expect = 2e-45
Identities = 98/233 (42%), Positives = 146/233 (62%), Gaps = 4/233 (1%)
Query: 7 QAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
+ GY ++T FSP G+L Q+ YA AV GA +VG+K +GVVLA EK+ S L + +S
Sbjct: 3 ERGYSFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKATNGVVLATEKKQKSILYDEQSA 62
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
K+ I HI SG+ D RVLV RAR AQ + L Y EP P A +V+++ + Q +T
Sbjct: 63 HKVEPITKHIGMVYSGMGPDYRVLVRRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYT 122
Query: 127 QYGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDM 185
Q GGVRPFG +LL+AG ++ +P L+++DPSGAYFAWKA A+G E +Y +D+
Sbjct: 123 QSGGVRPFGVSLLIAGWDEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDL 182
Query: 186 TLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
L++AI AI L ++ E + + +NIEV + + F++L+ E++ +L +
Sbjct: 183 ELEDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFKRLTPAEVKDYLAAI 233
>gi|8394072 proteasome (prosome, macropain) subunit, alpha type 5 [Rattus
norvegicus] >gi|464457|sp|P34064|PRCZ_RAT PROTEASOME
ZETA CHAIN (MACROPAIN ZETA CHAIN) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX ZETA CHAIN) >gi|285143|pir||JX0229
multicatalytic endopeptidase complex (EC 3.4.99.46) zeta
chain - rat >gi|286254|dbj|BAA01588.1| (D10756)
proteasome subunit R-ZETA [Rattus sp.]
Length = 241
Score = 183 bits (459), Expect = 2e-45
Identities = 104/238 (43%), Positives = 146/238 (60%), Gaps = 14/238 (5%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA E K G+TA+G++ +GV LAVEKRITS L+EP S EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEGHKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI A SG+IADA+ L+++AR+E Q H TY E + + + + +L Q+G
Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFG 124
Query: 130 G--------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
RPFG ALL GV++K P+L+ DPSG + A AIGS A + ++
Sbjct: 125 EEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEV 184
Query: 181 YRDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
Y TL EAIK ++ L + M EK +A NIE+A + + F +KEE+E+ + ++
Sbjct: 185 YHKSTTLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEELEEVIKDI 241
>dbj|BAA96830.1| (AB026559) alpha 2 subunit of 20S proteasome [Oryza sativa]
Length = 235
Score = 182 bits (458), Expect = 3e-45
Identities = 99/230 (43%), Positives = 146/230 (63%), Gaps = 3/230 (1%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
Y ++T FSP G+L Q+ +A AV G T++G+K +GVV+A EK++ S L++ S +KI
Sbjct: 6 YSFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKAANGVVIATEKKLPSILVDETSVQKI 65
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ +I SG+ D RVLV ++R +AQ + Y E P+ +V++ + Q TQ G
Sbjct: 66 QSLTPNIGVVYSGMGPDFRVLVRKSRKQAQQYYRLYKETIPVTQLVRETAAVMQEFTQSG 125
Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
GVRPFG +LL+AG +D P+LY+ DPSG+YF+WKA A+G + A E +Y +DM LD
Sbjct: 126 GVRPFGVSLLIAGYDDNGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMELD 185
Query: 189 EAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
+AI AI L + E + SA NIE+ +I D++F+ LS EI+ FL EV
Sbjct: 186 DAIHTAILTLKEGYEGQISANNIEIGIIR-SDREFKVLSPAEIKDFLEEV 234
>gb|AAC34196.1| (AF017649) alpha4 proteasome subunit [Drosophila virilis]
Length = 247
Score = 182 bits (457), Expect = 4e-45
Identities = 105/246 (42%), Positives = 155/246 (62%), Gaps = 8/246 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRA+T+FSPDGRL QV YA+EAV++G+TAVGV+ + VVL VEK+ ++L E + KI
Sbjct: 5 YDRAVTIFSPDGRLLQVEYAQEAVRKGSTAVGVRGGNCVVLGVEKKSVAKLQEDRTVRKI 64
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ DH+ A +G + DAR+L+NRA++E Q HRL +P L I + I LKQ +TQ
Sbjct: 65 CVL-DHVVMAFAG-LTDARILINRAQVECQSHRLNVEDPVTLEYITRYIAQLKQKYTQSN 122
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
G RPFG + L+ G + P L++T+PSG ++ +KA A G T FE +YR++
Sbjct: 123 GRRPFGISCLIGGFDADGSPYLFQTEPSGIFYEYKANATGCSAKTVREFFEKQYREEEVS 182
Query: 188 DE--AIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEE 245
E A+KLAI AL + + N+EVA++ K + L ++ I ++L + KE EEE
Sbjct: 183 TERGAVKLAIRALLEVAQS-GQHNLEVAIME-NGKPLKMLDRKVILEYLDIIEKEKEEEL 240
Query: 246 VKEKEE 251
K+K++
Sbjct: 241 EKKKQK 246
>gb|AAF60416.1| (AC006708) contains similarity to Pfam family PF00227 (Proteasome
A-type and B-type), score=170.2, E=3.3e-47, N=1
[Caenorhabditis elegans]
Length = 283
Score = 179 bits (450), Expect = 2e-44
Identities = 95/247 (38%), Positives = 155/247 (62%), Gaps = 7/247 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
YD T+FSP+GRL+QV YA EA+ T +G+ +G+V+A E++ +L++ EK
Sbjct: 38 YDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILSSEGIVVAAERKNVHKLLDDSVMTEK 97
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
++++ D+I+ +GI ADA +L+N R A +R +YGE P+ +V+ +C+ KQ +TQ
Sbjct: 98 VYRLSDNISCTVAGITADANILINHLRWWAASYRNSYGEEMPVEQLVQNLCNEKQRYTQI 157
Query: 129 GGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GG RPFG +LL G + +LY++DPSG Y WKA IGS A+ + + +Y+
Sbjct: 158 GGKRPFGVSLLYIGWDKHYGYQLYQSDPSGNYTGWKATCIGSNHQAAVTLLKQEYKSP-N 216
Query: 187 LDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVMKEVEE 243
L+EA +LAI L KT++ K ++E +E+AV+T +D K +L+ +E++ + E K+ +E
Sbjct: 217 LEEAKQLAIKVLWKTLDVKLASEKVEMAVLTRRDGKTVLEELTTKEVDALIAEHEKKEKE 276
Query: 244 EEVKEKE 250
E EK+
Sbjct: 277 AETAEKK 283
>sp|P40301|PRC3_DROME PROTEASOME 25 KDA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 25
KDA SUBUNIT) >gi|486825|pir||S36116 multicatalytic
endopeptidase complex (EC 3.4.99.46) chain PROS-Dm25 -
fruit fly (Drosophila melanogaster)
>gi|397850|emb|CAA49783.1| (X70304) proteasome, 25kDa
subunit [Drosophila melanogaster]
>gi|7299630|gb|AAF54814.1| (AE003696) Pros25 gene
product [Drosophila melanogaster]
Length = 234
Score = 179 bits (449), Expect = 3e-44
Identities = 96/230 (41%), Positives = 140/230 (60%), Gaps = 4/230 (1%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
Y ++T FSP G+L Q+ YA AV GA +VG+ +GVV+A E + S L E S ++
Sbjct: 6 YSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRV 65
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
I +HI SG+ D R+LV +AR AQ + LTY EP P++ +V+++ L Q +TQ G
Sbjct: 66 EMIYNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSG 125
Query: 130 GVRPFGAALLMAG-VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
GVRPFG +LL+ G ND+P LY++DPSGAYFAWKA A+G E +Y +D+ LD
Sbjct: 126 GVRPFGVSLLICGWDNDRPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLELD 185
Query: 189 EAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
+A+ AI L + E K +A+NIE+ + F++L I+ +L +
Sbjct: 186 DAVHTAILTLKEGFEGKMTADNIEIGI--CDQNGFQRLDPASIKDYLASI 233
>gb|AAF46651.1| (AE003452) Pros29 gene product [Drosophila melanogaster]
Length = 264
Score = 179 bits (449), Expect = 3e-44
Identities = 99/253 (39%), Positives = 156/253 (61%), Gaps = 11/253 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA EA+ T +G+ +DG++LA E R T++L++ EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I++++D++ + +GI +DA VL + RL AQ ++ +YGE P +V +CD+KQ +TQY
Sbjct: 65 IYRLNDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQY 124
Query: 129 GGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFE----DKYR 182
GG RPFG +LL G ++K +LY++DPSG Y WKA IG+ A+++ + DK
Sbjct: 125 GGKRPFGVSLLYMGWDNKYGYQLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKEN 184
Query: 183 DDMTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVM 238
+TL +A LAI L+ T++ K + E +E+A + D K + L K ++EK + +
Sbjct: 185 VKLTLADAKDLAIKVLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYT 244
Query: 239 KEVEEEEVKEKEE 251
K E E +KE+
Sbjct: 245 KVQAEAEAAKKEK 257
>sp|P18053|PRC9_DROME PROTEASOME 29 KD SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 29
KD SUBUNIT) >gi|103322|pir||S10318 multicatalytic
endopeptidase complex (EC 3.4.99.46) chain PROS-29 -
fruit fly (Drosophila melanogaster)
>gi|8380|emb|CAA36555.1| (X52319) PROS-29 protein (AA
1-264) [Drosophila melanogaster]
Length = 264
Score = 177 bits (444), Expect = 1e-43
Identities = 99/253 (39%), Positives = 155/253 (61%), Gaps = 11/253 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEK 68
YD T+FSP+GRL+QV YA EA+ T +G+ +DG++LA E R T++L++ EK
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEK 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I++ +D++ + +GI +DA VL + RL AQ ++ +YGE P +V +CD+KQ +TQY
Sbjct: 65 IYRRNDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQY 124
Query: 129 GGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFE----DKYR 182
GG RPFG +LL G ++K +LY++DPSG Y WKA IG+ A+++ + DK
Sbjct: 125 GGKRPFGVSLLYMGWDNKYGYQLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKEN 184
Query: 183 DDMTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKK--FRKLSKEEIEKFLGEVM 238
+TL +A LAI L+ T++ K + E +E+A + D K + L K ++EK + +
Sbjct: 185 VKLTLADAKDLAIKVLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYT 244
Query: 239 KEVEEEEVKEKEE 251
K E E +KE+
Sbjct: 245 KVQAEAEAAKKEK 257
>gi|6321692 Proteasome subunit; Pup2p [Saccharomyces cerevisiae]
>gi|1709764|sp|P32379|PRCZ_YEAST PROTEASOME COMPONENT
PUP2 (MACROPAIN SUBUNIT PUP2) (PROTEINASE YSCE SUBUNIT
PUP2) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT
PUP2) >gi|2118148|pir||S64585 multicatalytic
endopeptidase complex (EC 3.4.99.46) chain PUP2 - yeast
(Saccharomyces cerevisiae) >gi|1323460|emb|CAA97282.1|
(Z73038) ORF YGR253c [Saccharomyces cerevisiae]
>gi|1502356|emb|CAA67615.1| (X99228) PUP2 [Saccharomyces
cerevisiae]
Length = 260
Score = 174 bits (437), Expect = 8e-43
Identities = 100/251 (39%), Positives = 143/251 (56%), Gaps = 12/251 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR ++ FSP+GRLFQV Y+ EA+K G+TA+G+ K+GVVL VEKR TS L+E +S EKI
Sbjct: 8 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI A SG+ ADAR ++ AR A H L Y E + + + +CDL +
Sbjct: 68 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGA 127
Query: 130 G------VRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
RPFG ALL+AG +D +L+ +PSG ++ + A AIGSG A A +++
Sbjct: 128 SGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEW 187
Query: 182 RDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEV 241
+TL EA L + L + ME+ EN K F+ E+ E++KE+
Sbjct: 188 HSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEK----TAELIKEL 243
Query: 242 EEEEVKEKEED 252
+E+E E E+
Sbjct: 244 KEKEAAESPEE 254
>pdb|1G0U|D Chain D, A Gated Channel Into The Proteasome Core Particle
>gi|11514009|pdb|1G0U|R Chain R, A Gated Channel Into
The Proteasome Core Particle
Length = 241
Score = 174 bits (437), Expect = 8e-43
Identities = 99/241 (41%), Positives = 140/241 (58%), Gaps = 9/241 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR ++ FSP+GRLFQV Y+ EA+K G+TA+G+ K+GVVL VEKR TS L+E +S EKI
Sbjct: 8 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI A SG+ ADAR ++ AR A H L Y E + + + +CDL
Sbjct: 68 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAM-- 125
Query: 130 GVRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
RPFG ALL+AG +D +L+ +PSG ++ + A AIGSG A A +++ +TL
Sbjct: 126 -SRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTL 184
Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
EA L + L + ME+ EN K F+ E+ E++KE++E+E
Sbjct: 185 KEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEK----TAELIKELKEKEAA 240
Query: 248 E 248
E
Sbjct: 241 E 241
>emb|CAA46111.1| (X64918) PUP2 [Saccharomyces cerevisiae]
Length = 260
Score = 173 bits (433), Expect = 2e-42
Identities = 99/251 (39%), Positives = 143/251 (56%), Gaps = 12/251 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR ++ FSP+GRLFQV Y+ EA+K G+TA+G+ K+GVVL VEKR TS L+E +S EKI
Sbjct: 8 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI A SG+ ADAR ++ AR A H L Y E + + + +CDL +
Sbjct: 68 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGA 127
Query: 130 G------VRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
RPFG ALL+AG +D +L+ +PSG ++ + A AIGSG A A +++
Sbjct: 128 SGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEW 187
Query: 182 RDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEV 241
++L EA L + L + ME+ EN K F+ E+ E++KE+
Sbjct: 188 HSSLSLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEK----TAELIKEL 243
Query: 242 EEEEVKEKEED 252
+E+E E E+
Sbjct: 244 KEKEAAESPEE 254
>emb|CAA74025.1| (Y13691) multicatalytic endopeptidase complex, proteasome
component, alpha subunit [Arabidopsis thaliana]
Length = 245
Score = 170 bits (427), Expect = 1e-41
Identities = 93/233 (39%), Positives = 144/233 (60%), Gaps = 6/233 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AGYDR IT+FSP+GRLFQV YA +AVK G T++GV+ KD V + +K++ +L++ S
Sbjct: 6 AGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSV 65
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
+F I +I ++GI ADAR LV +AR +A R TYG P+ ++ K I D Q++T
Sbjct: 66 THLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYT 125
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
Q+ +RP G ++ GV+++ P LY+ DP+G ++ KA + G A+ E K +++
Sbjct: 126 QHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKEN 185
Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
T DE ++ AI AL +++ A IEV V+ ++ +FR L+ EEIE+ L
Sbjct: 186 PSFTFDETVQTAISALQSVLQEDFKATEIEVGVVRAENPEFRALTTEEIEEHL 238
>dbj|BAB09993.1| (AB023031) multicatalytic endopeptidase complex alpha subunit-like
[Arabidopsis thaliana]
Length = 246
Score = 170 bits (427), Expect = 1e-41
Identities = 93/233 (39%), Positives = 144/233 (60%), Gaps = 6/233 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AGYDR IT+FSP+GRLFQV YA +AVK G T++GV+ KD V + +K++ +L++ S
Sbjct: 7 AGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
+F I +I ++GI ADAR LV +AR +A R TYG P+ ++ K I D Q++T
Sbjct: 67 THLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYT 126
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
Q+ +RP G ++ GV+++ P LY+ DP+G ++ KA + G A+ E K +++
Sbjct: 127 QHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKEN 186
Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
T DE ++ AI AL +++ A IEV V+ ++ +FR L+ EEIE+ L
Sbjct: 187 PSFTFDETVQTAISALQSVLQEDFKATEIEVGVVRAENPEFRALTTEEIEEHL 239
>pdb|1G65|D Chain D, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
Molecular Basis For Selectivity Of
Alpha,Beta-Epoxyketone Proteasome Inhibitors
>gi|11513430|pdb|1G65|R Chain R, Crystal Structure Of
Epoxomicin:20s Proteasome Reveals A Molecular Basis For
Selectivity Of Alpha,Beta-Epoxyketone Proteasome
Inhibitors >gi|3114273|pdb|1RYP|E Chain E, Crystal
Structure Of The 20s Proteasome From Yeast At 2.4
Angstroms Resolution >gi|3114287|pdb|1RYP|S Chain S,
Crystal Structure Of The 20s Proteasome From Yeast At
2.4 Angstroms Resolution
Length = 242
Score = 169 bits (424), Expect = 3e-41
Identities = 98/246 (39%), Positives = 140/246 (56%), Gaps = 12/246 (4%)
Query: 11 DRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIF 70
DR ++ FSP+GRLFQV Y+ EA+K G+TA+G+ K+GVVL VEKR TS L+E +S EKI
Sbjct: 1 DRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKIV 60
Query: 71 QIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGG 130
+ID HI A SG+ ADAR ++ AR A H L Y E + + + +CDL +
Sbjct: 61 EIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGAS 120
Query: 131 ------VRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR 182
RPFG ALL+AG +D +L+ +PSG ++ + A AIGSG A A +++
Sbjct: 121 GEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWH 180
Query: 183 DDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVE 242
+TL EA L + L + ME+ EN K F+ E+ E++KE++
Sbjct: 181 SSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEK----TAELIKELK 236
Query: 243 EEEVKE 248
E+E E
Sbjct: 237 EKEAAE 242
>emb|CAB95217.1| (AL359773) proteasome subunit [Leishmania major]
Length = 407
Score = 169 bits (424), Expect = 3e-41
Identities = 94/236 (39%), Positives = 142/236 (59%), Gaps = 18/236 (7%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE----- 64
YD T FSP+GRL+QV YA EA+++ T +GV KDGVVLA EK + L + E
Sbjct: 127 YDSRTTTFSPEGRLYQVEYAVEAIQQAGTVIGVCTKDGVVLAGEKMVPHPLFDSENMQDK 186
Query: 65 --SYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLK 122
S EK+++I +HI + +G+ +DA L+N ARL A H+ T+ EP + + + +CD K
Sbjct: 187 NISGEKMYKIAEHIGCSVAGVTSDAYALLNYARLSALRHQYTFQEPIAIEDLCRILCDEK 246
Query: 123 QMHTQYGGVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
Q++TQYGGVRP+G + L+ G + +LY T+PSG Y AW A AIG A ++ +
Sbjct: 247 QLYTQYGGVRPYGVSFLLVGWDRYYGYQLYSTEPSGDYSAWSAYAIGQNDQVAHSLLKKD 306
Query: 181 YRDDMTLDEAIKLAIFALAKTME--KPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
+ ++MTL++ + LA+ L KTM+ K +EVAV+ RK+ +++ L
Sbjct: 307 WHENMTLEDGMLLALRVLGKTMDTAKIDLGRVEVAVM-------RKVPASNVDQLL 355
>gb|AAC32054.1| (AF043518) 20S proteasome subunit PAA1 [Arabidopsis thaliana]
Length = 246
Score = 169 bits (423), Expect = 4e-41
Identities = 92/233 (39%), Positives = 144/233 (61%), Gaps = 6/233 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AGYDR IT+FSP+GRLFQV YA +AVK G T++GV+ KD V + +K++ +L++ S
Sbjct: 7 AGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
+F I +I ++GI ADAR LV +AR +A R TYG P+ ++ K I D Q++T
Sbjct: 67 THLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYT 126
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
Q+ +RP G ++ GV+++ P LY+ DP+G ++ KA + G A+ E++ + +
Sbjct: 127 QHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEEEMKGN 186
Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
T DE ++ AI AL +++ A IEV V+ ++ +FR L+ EEIE+ L
Sbjct: 187 PSFTFDETVQTAISALQSVLQEDFKATEIEVGVVRAENPEFRALTTEEIEEHL 239
>gb|AAG28528.1|AF198387_1 (AF198387) 20S proteasome alpha 3 subunit [Trypanosoma brucei]
Length = 286
Score = 168 bits (422), Expect = 5e-41
Identities = 98/272 (36%), Positives = 151/272 (55%), Gaps = 29/272 (10%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE----- 64
YD T FSP+GRL+QV YA EA+ + T +G+ GVVL E+ L + E
Sbjct: 5 YDSRTTTFSPEGRLYQVEYAEEAISQAGTIIGILTTGGVVLDAERGQQHGLFDTENMEDI 64
Query: 65 --SYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLK 122
S EK+++I +H+ + +G+ +DA L+N ARL A H ++ EP + + +CD K
Sbjct: 65 NISGEKVYKISNHLGCSVAGVTSDAYALINYARLSAARHFYSFQEPIAAEDLCRMVCDEK 124
Query: 123 QMHTQYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
Q++TQYGGVRPFG + L AG + +LY TD SG Y AW+A A+G A ++ +
Sbjct: 125 QLYTQYGGVRPFGVSFLFAGWDRHYGYQLYHTDASGNYSAWRAYAVGQNDQVAQSLLKRD 184
Query: 181 YRDDMTLDEAIKLAIFALAKTME--KPSAENIEVAVI---------------TVKDK--- 220
++ ++TL+E I L + L KTM+ K + E +EVAV+ V K
Sbjct: 185 WKPELTLEEGIVLCLRVLGKTMDAVKLTPERLEVAVLHRVQAPLTQKLLDPYGVNPKMVP 244
Query: 221 KFRKLSKEEIEKFLGEVMKEVEEEEVKEKEED 252
F+ L+ EE++ + E ++ E EE +E E++
Sbjct: 245 SFKILTDEELKPHVDEANRQREAEEAEEAEKE 276
>pir||S72226 multicatalytic endopeptidase complex (EC 3.4.99.46) alpha-type
chain Pros28.1B, testes-specific - fruit fly
(Drosophila melanogaster) >gi|1220188|gb|AAC47281.1|
(U46009) testes-specific proteasome subunit [Drosophila
melanogaster]
Length = 249
Score = 168 bits (421), Expect = 6e-41
Identities = 92/241 (38%), Positives = 147/241 (60%), Gaps = 8/241 (3%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYDRA+T++SPDG L QV YA+EAV+RG+T +G++ + +V+ VEKR L E K
Sbjct: 4 GYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRK 63
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I +DDH+ SG+ ADAR+LV+RA++EAQ HRL + +P + I + I LKQ +TQ
Sbjct: 64 ICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQS 123
Query: 129 GGVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
G RPFG + L+ G ++ P L++TDPSG ++ W+A G + + + +K+ D++
Sbjct: 124 NGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRS-SQPVRDYMEKHADEI- 181
Query: 187 LDEAIKLAIFALAKTMEKPSAEN---IEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
L A + I + +T+ S+ N +EVAV+ + + R + + + V +E+E+
Sbjct: 182 LTIADERGIKHIVRTLVSVSSLNHTQMEVAVLKYR-QPLRMIDHQVLADLERTVRREIED 240
Query: 244 E 244
E
Sbjct: 241 E 241
>gb|AAF47215.1| (AE003464) Pros28.1B gene product [Drosophila melanogaster]
Length = 252
Score = 167 bits (419), Expect = 1e-40
Identities = 93/241 (38%), Positives = 143/241 (58%), Gaps = 9/241 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDRA+T++SPDG L QV YA+EAV+RG+T +G++ + +V+ VEKR L E KI
Sbjct: 5 YDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKI 64
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+DDH+ SG+ ADAR+LV+RA++EAQ HRL + +P + I + I LKQ +TQ
Sbjct: 65 CMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSN 124
Query: 130 GVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
G RPFG + L+ G ++ P L++TDPSG ++ W+A G E + +T+
Sbjct: 125 GRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTI 184
Query: 188 -DEAIKLAIFALAKTMEKPSAEN---IEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
DEA AI + +T+ S+ N +EVAV+ + + R + + + V +E+E+
Sbjct: 185 ADEA--AAIKHIVRTLVSVSSLNHTQMEVAVLKYR-QPLRMIDHQVLADLERTVRREIED 241
Query: 244 E 244
E
Sbjct: 242 E 242
>pir||T02089 proteasome chain - rice >gi|2570505|gb|AAB82138.1| (AF022735)
proteasome component [Oryza sativa]
Length = 261
Score = 167 bits (418), Expect = 1e-40
Identities = 91/224 (40%), Positives = 139/224 (61%), Gaps = 3/224 (1%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
Y ++T FSP G+L Q+N+A AV G T++G+K +GV +A EK++ S L++ S +KI
Sbjct: 6 YSFSLTTFSPSGKLVQINHALTAVGSGQTSLGIKAANGVFVATEKKLPSILVDETSVQKI 65
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ ++ SG+ D RVLV ++ +AQ Y E P+ +V++ + Q TQ G
Sbjct: 66 QSLTPNVGVVYSGMGPDFRVLVRKSPKQAQQCCRLYKETMPVTQLVRETAAVMQEFTQSG 125
Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLD 188
GVRPFG +LL+AG +D P+LY+ DPSG+YF+WKA A+G + A E ++ +DM LD
Sbjct: 126 GVRPFGVSLLIAGYDDNGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRHTEDMELD 185
Query: 189 EAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIE 231
+AI I L + E + SA NIE+ +I D++F+ LS EI+
Sbjct: 186 DAIHTGILILKEGYEGQISANNIEIGIIR-SDREFKVLSPAEIK 228
>gb|AAF55802.1| (AE003731) Pros28.1A gene product [Drosophila melanogaster]
Length = 249
Score = 166 bits (417), Expect = 2e-40
Identities = 98/237 (41%), Positives = 137/237 (57%), Gaps = 6/237 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
Y RA+T+FSPDG L QV YA+EAV++G+TAVGV+ + VVL VEK S + E + KI
Sbjct: 5 YGRALTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVRKI 64
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+D H+A A +G+ ADAR+L+NR ++E Q HRL + L I + + LKQ +TQ
Sbjct: 65 SMLDRHVALAFAGLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCN 124
Query: 130 GVRPFGAALLMAGV--NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD--M 185
G RPFG + L+ G+ + L+ T+PSG + +KA A G NT FE Y D
Sbjct: 125 GRRPFGISCLIGGIDADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHEVT 184
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVE 242
T +AIKLA+ AL + + S +EVAV+ K + L I + + V E E
Sbjct: 185 TKCDAIKLAMRALLEVTQM-SQMRLEVAVLE-NGKPMKMLDSVVISEIVKIVQNEKE 239
>gb|AAB34631.1| Doa5, PUP2=alpha-type proteasome subunit zeta homolog
[Saccharomyces cerevisiae, Peptide, 243 aa]
Length = 243
Score = 166 bits (416), Expect = 2e-40
Identities = 93/236 (39%), Positives = 134/236 (56%), Gaps = 8/236 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR ++ FSP+GRLFQV Y+ EA+K G+TA+G+ K+GVVL VEKR TS L+E +S EKI
Sbjct: 8 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID HI A SG+ ADAR ++ AR A H L Y E + + + +CDL +
Sbjct: 68 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGA 127
Query: 130 G------VRPFGAALLMAG--VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
RPFG ALL+AG +D +L+ +PSG ++ + A AIGSG A A +++
Sbjct: 128 SGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEW 187
Query: 182 RDDMTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
++L EA L + L + ME+ EN K F+ E+ + + E+
Sbjct: 188 HSSLSLKEAELLVLKILKQVMEEKLDENNAQLTCITKQDGFKIYDNEKTAELIKEL 243
>pir||T21350 hypothetical protein F25H2.9 - Caenorhabditis elegans
>gi|3876333|emb|CAB02097.1| (Z79754) contains similarity
to Pfam domain: PF00227 (Proteasome A-type and B-type),
Score=168.0, E-value=5.3e-47, N=1~cDNA EST EMBL:T00300
comes from this gene~cDNA EST EMBL:T00299 comes from
this gene~cDNA EST yk92h1.3 comes from this gene~cDNA
EST y>
Length = 248
Score = 166 bits (416), Expect = 2e-40
Identities = 96/241 (39%), Positives = 149/241 (60%), Gaps = 19/241 (7%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YDR + FSP+GRLFQV YA EAVK G+T++G+K +GV+LA EKR TS+L+ ++ EKI
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAVKLGSTSIGIKTSEGVLLAAEKRSTSKLMVNDAIEKI 67
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
++D HI +G+IAD+R LV RA++EAQ TY + + + + +L Q+G
Sbjct: 68 SKVDQHIGVTFAGLIADSRTLVERAQIEAQNFWFTYNRKIRVEDVTQSVANLA---LQFG 124
Query: 130 G-------VRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY 181
RPFG A+L AGV+ + +L+ DPSG + KA +IG+ + A +++Y
Sbjct: 125 DDDVKASMSRPFGVAMLFAGVDQEGAKLFHLDPSGTFIDCKAKSIGAASDGAEQNLKEQY 184
Query: 182 RDDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVI--TVKDK-----KFRKLSKEEIEKF 233
D +T+ E +K+A+ L + M EK ++ N+EV VI TV K +F ++S EE+++
Sbjct: 185 HDALTIKEGLKMALAILKQVMEEKLNSANVEVVVIKPTVDAKGRPIGEFTRVSNEELDQV 244
Query: 234 L 234
+
Sbjct: 245 I 245
>emb|CAB39975.1| (Y16644) PRCI [Nicotiana tabacum]
Length = 246
Score = 165 bits (414), Expect = 4e-40
Identities = 90/232 (38%), Positives = 143/232 (60%), Gaps = 6/232 (2%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
GYDR IT+FSP+GRLFQV YA +AVK G T++GV+ KD V + +K++ +L++ S
Sbjct: 8 GYDRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSVCVVTQKKVPDKLLDQTSVS 67
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
+F I ++ ++G+ ADAR LV +AR EA R YG P+ V+ K I D Q++TQ
Sbjct: 68 HLFPITKYLGLLATGMTADARTLVQQARNEAAEFRFKYGYEMPVDVLSKWIADKSQVYTQ 127
Query: 128 YGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD- 184
+ +RP G ++ G++++ P+L++ DP+G +F KA + GS A+ E K ++D
Sbjct: 128 HAYMRPLGVVAMILGIDEEKGPQLFKCDPAGHFFGHKATSAGSKEQEAINFLEKKMKNDP 187
Query: 185 -MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
+ +E ++ AI AL +++ A IEV V+ +D FR L+ EEI++ L
Sbjct: 188 AFSYEETVQTAISALQSVLQEDFKASEIEVGVVKKEDPIFRVLTTEEIDEHL 239
>pir||T06142 multicatalytic endopeptidase complex (EC 3.4.99.46) iota chain -
soybean >gi|3377794|gb|AAC28135.1| (AF034572) proteasome
IOTA subunit [Glycine max]
Length = 246
Score = 165 bits (413), Expect = 5e-40
Identities = 90/232 (38%), Positives = 142/232 (60%), Gaps = 6/232 (2%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
GY+R IT+FSP+GRLFQV YA +AVK G T++GV+ KD + + K++ +L++ S
Sbjct: 8 GYNRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSICVVTHKKVPDKLLDNTSVT 67
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
+F I ++ ++G+ ADAR LV +AR EA R TYG P+ V+ K I D Q++TQ
Sbjct: 68 HLFPITKYLGLLATGMTADARTLVQQARNEAAEFRFTYGYEMPVDVLAKWIADKSQVYTQ 127
Query: 128 YGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD- 184
+ +RP G ++ G++D+ P+LY+ DP+G YF KA + G A+ E K ++D
Sbjct: 128 HAYMRPLGVVAMVLGIDDEYGPQLYKCDPAGHYFGHKATSAGLKDQEAINFLEKKMKNDP 187
Query: 185 -MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
T +E ++ AI AL +++ A IEV V+ + +FR L+ +EI++ L
Sbjct: 188 SFTYEETVQTAISALQSVLQEDFKATEIEVGVVRKDNPEFRVLTTDEIDEHL 239
>gi|6323547 proteasome component Y7; Pre8p [Saccharomyces cerevisiae]
>gi|130880|sp|P23639|PRC3_YEAST PROTEASOME COMPONENT Y7
(MACROPAIN SUBUNIT Y7) (PROTEINASE YSCE SUBUNIT 7)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT Y7)
>gi|67727|pir||SNBYY7 multicatalytic endopeptidase
complex (EC 3.4.99.46) chain Y7 - yeast (Saccharomyces
cerevisiae) >gi|11513413|pdb|1G65|A Chain A, Crystal
Structure Of Epoxomicin:20s Proteasome Reveals A
Molecular Basis For Selectivity Of
Alpha,Beta-Epoxyketone Proteasome Inhibitors
>gi|11513427|pdb|1G65|O Chain O, Crystal Structure Of
Epoxomicin:20s Proteasome Reveals A Molecular Basis For
Selectivity Of Alpha,Beta-Epoxyketone Proteasome
Inhibitors >gi|11513992|pdb|1G0U|A Chain A, A Gated
Channel Into The Proteasome Core Particle
>gi|11514006|pdb|1G0U|O Chain O, A Gated Channel Into
The Proteasome Core Particle >gi|3114270|pdb|1RYP|B
Chain B, Crystal Structure Of The 20s Proteasome From
Yeast At 2.4 Angstroms Resolution >gi|3114284|pdb|1RYP|P
Chain P, Crystal Structure Of The 20s Proteasome From
Yeast At 2.4 Angstroms Resolution
>gi|506482|emb|CAA40055.1| (X56731) proteasome Y7
subunit [Saccharomyces cerevisiae]
>gi|575711|emb|CAA86646.1| (Z46660) proteasome component
Y gene, len: 250, CAI:0.15, PRCX_YEAST P23639
[Saccharomyces cerevisiae]
Length = 250
Score = 164 bits (410), Expect = 1e-39
Identities = 93/239 (38%), Positives = 145/239 (59%), Gaps = 18/239 (7%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
Y ++T FSP G+L Q++YA AVK+G T++G+K +GVV+A EK+ +S L E+ K+
Sbjct: 5 YSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKV 64
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQI-HRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+ I A SG+ D RVLV+++R A ++ YGE P ++V ++ + Q TQ
Sbjct: 65 SLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQS 124
Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GGVRPFG +LL+AG ++ LY+ DPSG+YF WKA AIG G A E ++ D++
Sbjct: 125 GGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELE 184
Query: 187 LDEAIKLAIFALAKTME-KPSAENIEVAVI--------------TVKDKKFRKLSKEEI 230
L++AI +A+ L +++E + + + IE+A+I T K +FRKL+ +EI
Sbjct: 185 LEDAIHIALLTLKESVEGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQEI 243
>gi|6324938 proteasome component YC1 (protease yscE subunit 1); Pre10p
[Saccharomyces cerevisiae]
>gi|130847|sp|P21242|PRC8_YEAST PROTEASOME COMPONENT C1
(MACROPAIN SUBUNIT C1) (PROTEINASE YSCE SUBUNIT 1)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C1)
>gi|67729|pir||SNBYC1 multicatalytic endopeptidase
complex (EC 3.4.99.46) chain YC1 - yeast (Saccharomyces
cerevisiae) >gi|173204|gb|AAA35227.1| (M55436) yeast
proteasome subunit YC1 [Saccharomyces cerevisiae]
>gi|1420786|emb|CAA99691.1| (Z75270) ORF YOR362c
[Saccharomyces cerevisiae]
Length = 288
Score = 163 bits (409), Expect = 2e-39
Identities = 95/254 (37%), Positives = 138/254 (53%), Gaps = 4/254 (1%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + +VFSPDGR FQV YA +AV+ G T++G+KC DGVV AVEK ITS+L+ P+ K
Sbjct: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I +D HI SG+I D R LVNR R EA + Y P P+ ++ Q HT Y
Sbjct: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126
Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DKYRDD 184
VRPFG + + GV+ + LY +PSG+Y+ +K A G GR +A A E D + +
Sbjct: 127 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 186
Query: 185 MTLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
++ EA+K A + E ++ E+ + + L K L E + ++E
Sbjct: 187 LSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQKE 246
Query: 245 EVKEKEEDYSELDS 258
+ +ED + D+
Sbjct: 247 INGDDDEDEDDSDN 260
>gb|AAC32055.1| (AF043519) 20S proteasome subunit PAA2 [Arabidopsis thaliana]
>gi|4006819|gb|AAC95161.1| (AC005970) 20S proteasome
subunit (PAA2) [Arabidopsis thaliana]
Length = 246
Score = 162 bits (407), Expect = 3e-39
Identities = 88/233 (37%), Positives = 139/233 (58%), Gaps = 6/233 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AGYDR IT+FSP+GRLFQV YA +AVK G T++GV+ KD V + +K++ +L++ S
Sbjct: 7 AGYDRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
+F + ++ ++G+ AD+R LV +AR EA R YG P ++ K I D Q++T
Sbjct: 67 SHLFPVTKYLGLLATGMTADSRSLVQQARNEAAEFRFQYGYEMPADILAKWIADKSQVYT 126
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
Q+ +RP G ++ G++++ P LY+ DP+G ++ KA + G A+ E K +++
Sbjct: 127 QHAYMRPLGVVAMVLGIDEERGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKEN 186
Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
T DE ++ AI AL +++ A IEV V+ D FR L EEI++ L
Sbjct: 187 PAFTYDETVQTAISALQSVLQEDFKATEIEVGVVRADDPLFRSLRTEEIDEHL 239
>sp|Q27488|PRC3_CAEEL PROBABLE PROTEASOME COMPONENT C3 (MACROPAIN SUBUNIT C3)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C3)
>gi|7498128|pir||T20304 hypothetical protein D1054.2 -
Caenorhabditis elegans >gi|3875311|emb|CAA98441.1|
(Z74030) Similarity to Xenopus proteasome component C3
(SW:PRC3_XENLA), contains similarity to Pfam domain:
PF00227 (Proteasome A-type and B-type), Score=178.5,
E-value=3.4e-50, N=1~cDNA EST yk511b9.3 comes from this
gene~cDNA EST yk541h3.3 comes from >
Length = 231
Score = 161 bits (404), Expect = 6e-39
Identities = 94/230 (40%), Positives = 135/230 (57%), Gaps = 9/230 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
Y ++T FSP G+L Q+ YA AVK G +VG++ KDGVVLA E + S L + + K+
Sbjct: 5 YGFSLTTFSPSGKLMQIEYALNAVKNGQPSVGLRAKDGVVLATEN-VGSVLTDDQP--KV 61
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
QI HI SG+ D R+LV +AR A + + YGE P +V I + Q +TQ G
Sbjct: 62 EQISKHIGCVYSGMGPDFRILVKKARKIAMEYEMMYGEEMPTIQLVTDIAAVMQEYTQSG 121
Query: 130 GVRPFGAALLMAGVN---DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
GVRPFGA+LL+AG + +P L++ DPSGAYFAWKA A+G A E ++ + +
Sbjct: 122 GVRPFGASLLIAGWDKNPGRPLLFQCDPSGAYFAWKATALGKNDVNAKTFLEKRFSEALE 181
Query: 187 LDEAIKLAIFALAKTMEKPSAE-NIEVAVITVKDKKFRKLSKEEIEKFLG 235
LD+ I A+ L ++ + E N+EVAV F +L+K+++ LG
Sbjct: 182 LDDGIHTALLTLRESFDVGMNENNVEVAV--CNSTGFHRLTKQQVHDHLG 229
>sp|Q27563|PRC8_DICDI PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C8)
>gi|1408304|gb|AAB03671.1| (U61988) PrtD [Dictyostelium
discoideum]
Length = 248
Score = 161 bits (403), Expect = 8e-39
Identities = 77/186 (41%), Positives = 119/186 (63%), Gaps = 1/186 (0%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
+GYD ++ +SPDG+LFQV+YA +AV+ T V +K KDGVVL VEK + S+++ S
Sbjct: 6 SGYDLYVSTYSPDGKLFQVDYANKAVENSGTLVAIKAKDGVVLGVEKLVPSKMLCSGSNR 65
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
++ ID H+ A +G +ADAR L+ RAR EA+ ++ TYG+P P+ V+ ++I MHT
Sbjct: 66 RVHHIDTHVGVAIAGFLADARQLITRARSEAKNYKSTYGQPIPIKVLSQRIASYNHMHTL 125
Query: 128 YGGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
YG VRPFG ++ + G++ P+L+ +PSG+ + ++G G+ A E+ +MT
Sbjct: 126 YGSVRPFGCSIAITGIDQYGPQLFLVEPSGSCVGYFGASLGKGKQAAKNELEEIRFSEMT 185
Query: 187 LDEAIK 192
EAIK
Sbjct: 186 CREAIK 191
>pdb|1G65|F Chain F, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
Molecular Basis For Selectivity Of
Alpha,Beta-Epoxyketone Proteasome Inhibitors
>gi|11513432|pdb|1G65|T Chain T, Crystal Structure Of
Epoxomicin:20s Proteasome Reveals A Molecular Basis For
Selectivity Of Alpha,Beta-Epoxyketone Proteasome
Inhibitors >gi|3114275|pdb|1RYP|G Chain G, Crystal
Structure Of The 20s Proteasome From Yeast At 2.4
Angstroms Resolution >gi|3114289|pdb|1RYP|U Chain U,
Crystal Structure Of The 20s Proteasome From Yeast At
2.4 Angstroms Resolution
Length = 244
Score = 161 bits (402), Expect = 1e-38
Identities = 96/247 (38%), Positives = 139/247 (55%), Gaps = 14/247 (5%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + +VFSPDGR FQV YA +AV+ G T++G+KC DGVV AVEK ITS+L+ P+ K
Sbjct: 3 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 62
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I +D HI SG+I D R LVNR R EA + Y P P+ ++ Q HT Y
Sbjct: 63 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 122
Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DKYRDD 184
VRPFG + + GV+ + LY +PSG+Y+ +K A G GR +A A E D + +
Sbjct: 123 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 182
Query: 185 MTLDEAIKLA--IFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFL-GEVMKEV 241
++ EA+K A I LA K +E++ ++ + + KF+ G++++E
Sbjct: 183 LSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSE-------TNGLHKFVKGDLLQEA 235
Query: 242 EEEEVKE 248
+ KE
Sbjct: 236 IDFAQKE 242
>pdb|1G0U|F Chain F, A Gated Channel Into The Proteasome Core Particle
>gi|11514011|pdb|1G0U|T Chain T, A Gated Channel Into
The Proteasome Core Particle
Length = 248
Score = 161 bits (402), Expect = 1e-38
Identities = 96/247 (38%), Positives = 139/247 (55%), Gaps = 14/247 (5%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + +VFSPDGR FQV YA +AV+ G T++G+KC DGVV AVEK ITS+L+ P+ K
Sbjct: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I +D HI SG+I D R LVNR R EA + Y P P+ ++ Q HT Y
Sbjct: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126
Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE---DKYRDD 184
VRPFG + + GV+ + LY +PSG+Y+ +K A G GR +A A E D + +
Sbjct: 127 NSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEG 186
Query: 185 MTLDEAIKLA--IFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFL-GEVMKEV 241
++ EA+K A I LA K +E++ ++ + + KF+ G++++E
Sbjct: 187 LSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSE-------TNGLHKFVKGDLLQEA 239
Query: 242 EEEEVKE 248
+ KE
Sbjct: 240 IDFAQKE 246
>dbj|BAA96829.1| (AB026558) alpha 1 subunit of 20S proteasome [Oryza sativa]
Length = 246
Score = 160 bits (401), Expect = 1e-38
Identities = 89/233 (38%), Positives = 142/233 (60%), Gaps = 6/233 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AGYDR IT+FSP+GRL+QV YA +AVK G T++GV+ KD V + +K++ +L++ S
Sbjct: 7 AGYDRHITIFSPEGRLYQVEYAFKAVKSAGVTSIGVRGKDSVCVVTQKKVPDKLLDHTSV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
+F I +I ++G+ ADAR LV +AR EA R +G P+ V+ K I D Q++T
Sbjct: 67 THLFPITKYIGLLATGLTADARSLVYQARNEAAEFRFKWGYEMPVDVLAKWIADKAQVYT 126
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
Q+ +RP G ++ G +++ +L++ DP+G +F KA + G A+ E K +DD
Sbjct: 127 QHAYMRPLGVVAMVLGYDEEKNAQLFKCDPAGHFFGHKATSAGLKEQEAINFLEKKMKDD 186
Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFL 234
+ +E +++AI AL +++ A IEV V+ D+ FR L+ EEI++ L
Sbjct: 187 PQFSYEETVQIAISALQSVLQEDFKATEIEVGVVRKDDRVFRALTTEEIDQHL 239
>gb|AAF59183.1| (AE003839) Prosalpha1 gene product [alt 1] [Drosophila
melanogaster] >gi|7304147|gb|AAF59184.1| (AE003839)
Prosalpha1 gene product [alt 2] [Drosophila
melanogaster]
Length = 244
Score = 160 bits (400), Expect = 2e-38
Identities = 87/239 (36%), Positives = 149/239 (61%), Gaps = 8/239 (3%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAV-KRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AG+DR IT+FSP+GRL+QV YA +A+ + T V +K D V+A +K++T + I PE+
Sbjct: 7 AGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
+F+I I A +G IAD+R V +AR EA R YG P+ V+ ++I D+ Q++T
Sbjct: 67 THLFRITKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYT 126
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
Q +RP G ++++ +++ P +Y+TDP+G + +KA ++G+ A + E KY+ +
Sbjct: 127 QNAEMRPLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPN 186
Query: 185 MTLDEAIKLAIFALAKTME---KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
++ ++AI+LAI L+ + KP+ IE+ V++ D FR L + EIE+ L ++ ++
Sbjct: 187 LSEEKAIQLAISCLSSVLAIDFKPN--GIEIGVVSKSDPTFRILDEREIEEHLTKIAEK 243
>pir||S72225 multicatalytic endopeptidase complex (EC 3.4.99.46) alpha-type
chain Pros28.1A, testes-specific - fruit fly
(Drosophila melanogaster) >gi|1220186|gb|AAC47280.1|
(U46008) testes-specific proteasome subunit alpha-type
[Drosophila melanogaster]
Length = 249
Score = 159 bits (399), Expect = 2e-38
Identities = 95/237 (40%), Positives = 134/237 (56%), Gaps = 6/237 (2%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
Y RA+T+FSPDG L QV Y +EAV++G+TAVGV+ + VVL VEK S + E + KI
Sbjct: 5 YGRALTIFSPDGHLLQVEYGQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVRKI 64
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+D H+A A +G+ ADAR+L+NR ++E Q HRL + L I + + LKQ +TQ
Sbjct: 65 SMLDRHVALAFAGLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQVN 124
Query: 130 GVRPFGAALLMAGV--NDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD--M 185
G FG + L+ G+ + L+ T+PSG + +KA A G NT FE Y D
Sbjct: 125 GRPSFGISCLIGGIDADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHEVT 184
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVE 242
T +AIKLA+ AL + + S +EVAV+ K + L I + + V E E
Sbjct: 185 TKCDAIKLAMRALLEVTQM-SQMRLEVAVLE-NGKPMKMLDSVVISEIVKIVQNEKE 239
>gi|8394076 proteasome (prosome, macropain) subunit, alpha type 6 [Rattus
norvegicus] >gi|464447|sp|P34062|PRCI_HUMAN PROTEASOME
IOTA CHAIN (MACROPAIN IOTA CHAIN) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX IOTA CHAIN) (27 KDA PROSOMAL
PROTEIN) (PROS-27) (P27K) >gi|285141|pir||JX0230
multicatalytic endopeptidase complex (EC 3.4.99.46) iota
chain - rat >gi|418785|pir||S30274 multicatalytic
endopeptidase complex (EC 3.4.99.46) iota chain - human
>gi|35682|emb|CAA42052.1| (X59417) prosomal P27K protein
[Homo sapiens] >gi|286250|dbj|BAA01587.1| (D10755)
proteasome subunit R-IOTA [Rattus sp.]
>gi|446773|prf||1912298A prosomal RNA-binding protein
p27K [Homo sapiens]
Length = 246
Score = 159 bits (398), Expect = 3e-38
Identities = 85/235 (36%), Positives = 146/235 (61%), Gaps = 10/235 (4%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGA-TAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AG+DR IT+FSP+GRL+QV YA +A+ +G T+V V+ KD V+ +K++ +L++ +
Sbjct: 7 AGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
+F+I ++I +G+ AD+R V RAR EA + YG P+ ++ K+I D+ Q++T
Sbjct: 67 THLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYT 126
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD- 183
Q +RP G +++ G++++ P++Y+ DP+G Y +KA A G + + + E K +
Sbjct: 127 QNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKK 186
Query: 184 -DMTLDEAIKLAIFALAKTME---KPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
D T ++ ++ AI L+ + KPS IEV V+TV++ KFR L++ EI+ L
Sbjct: 187 FDWTFEQTVETAITCLSTVLSIDFKPS--EIEVGVVTVENPKFRILTEAEIDAHL 239
>sp|P90513|PRC8_ACACA PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C8)
>gi|1809142|gb|AAB41645.1| (U85398) multicatalytic
endopeptidase subunit C8 [Acanthamoeba castellanii]
Length = 252
Score = 159 bits (398), Expect = 3e-38
Identities = 93/250 (37%), Positives = 144/250 (57%), Gaps = 9/250 (3%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + T FSPDGR+FQV YA +AV TA+G++ KDGVVLAVEK + S+++ P + +
Sbjct: 5 GYDLSSTTFSPDGRVFQVEYAAKAVDNSGTALGLRVKDGVVLAVEKLLVSKMLVPNTNRR 64
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I +D H A SG++AD R LV+R R EA +R YG V+ +++ + Q+++ Y
Sbjct: 65 IHTVDRHCGLAMSGLVADGRQLVSRGRAEATSYREFYGTDISGKVLNERLSNFVQLYSLY 124
Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
G VRPFG ++++ V+ + P+LY +PSG + + VAIG G A E +MT
Sbjct: 125 GSVRPFGTSVILGCVDKNGPQLYMIEPSGISWGYFGVAIGKGARAAKTEIEKLKLSEMTA 184
Query: 188 DEAIKLAIFALAKTME--KPSAENIEVAVITVKDKKFRKLSK----EEIEKFLGEVMKEV 241
EAIK A + + K A +E++ + + K EE EK+ + ++
Sbjct: 185 REAIKEAAKIIYSVHDDAKDKAFELELSWVCEETGNLHKFVPKDLLEEAEKYAKQALE-- 242
Query: 242 EEEEVKEKEE 251
EEE++ E+E+
Sbjct: 243 EEEDMSEEED 252
>gi|6755198 proteasome (prosome, macropain) subunit, alpha type 6 [Mus
musculus] >gi|9910829|sp|Q9QUM9|PRCI_MOUSE PROTEASOME
IOTA CHAIN (MACROPAIN IOTA CHAIN) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX IOTA CHAIN)
>gi|5757651|gb|AAD50532.1|AF060087_1 (AF060087)
proteasome subunit iota [Mus musculus]
>gi|6649571|gb|AAF21459.1|U60288_1 (U60288) proteasome
subunit iota [Mus musculus]
Length = 246
Score = 158 bits (396), Expect = 5e-38
Identities = 85/235 (36%), Positives = 145/235 (61%), Gaps = 10/235 (4%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGA-TAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AG+DR IT+FSP+GRL+QV YA +A+ +G T+V V+ KD V+ +K++ +L++ +
Sbjct: 7 AGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
+F+I + I +G+ AD+R V RAR EA + YG P+ ++ K+I D+ Q++T
Sbjct: 67 THLFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYT 126
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD- 183
Q +RP G +++ G++++ P++Y+ DP+G Y +KA A G + + + E K +
Sbjct: 127 QNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKK 186
Query: 184 -DMTLDEAIKLAIFALAKTME---KPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
D T ++ ++ AI L+ + KPS IEV V+TV++ KFR L++ EI+ L
Sbjct: 187 FDWTFEQTVETAITCLSTVLSIDFKPS--EIEVGVVTVENPKFRILTEAEIDAHL 239
>gb|AAD33944.1|AF144749_1 (AF144749) 20S proteasome subunit alpha1 [Drosophila melanogaster]
Length = 244
Score = 158 bits (395), Expect = 7e-38
Identities = 86/239 (35%), Positives = 148/239 (60%), Gaps = 8/239 (3%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAV-KRGATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AG+DR IT+FSP+GRL+QV YA +A+ + T V +K D V+A +K++T + I PE+
Sbjct: 7 AGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
+F+I I A +G IAD+R V + R EA R YG P+ V+ ++I D+ Q++T
Sbjct: 67 THLFRITKDIGCAMTGRIADSRSQVQKGRYEAANFRYKYGYEMPVDVLCRRIADITQVYT 126
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD 184
Q +RP G ++++ +++ P +Y+TDP+G + +KA ++G+ A + E KY+ +
Sbjct: 127 QNAEMRPLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPN 186
Query: 185 MTLDEAIKLAIFALAKTME---KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
++ ++AI+LAI L+ + KP+ IE+ V++ D FR L + EIE+ L ++ ++
Sbjct: 187 LSEEKAIQLAISCLSSVLAIDFKPN--GIEIGVVSKSDPTFRILDEREIEEHLTKIAEK 243
>gi|8394066 proteasome (prosome, macropain) subunit, alpha type 3 [Rattus
norvegicus] >gi|130860|sp|P18422|PRC8_RAT PROTEASOME
COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C8) (PROTEASOME SUBUNIT K)
>gi|67731|pir||SNRTC8 multicatalytic endopeptidase
complex (EC 3.4.99.46) chain C8 - rat
>gi|56639|emb|CAA39457.1| (X55985) multicatalytic
proteinase subunit K [Rattus rattus]
>gi|203207|gb|AAA40840.1| (M58593) proteasome component
C8 [Rattus norvegicus] >gi|220879|dbj|BAA14302.1|
(D90258) proteasome subunit C8 [Rattus rattus]
Length = 255
Score = 156 bits (390), Expect = 3e-37
Identities = 88/245 (35%), Positives = 134/245 (53%), Gaps = 8/245 (3%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + + FSPDGR+FQV YA +AV+ +TA+G++CKDGVV VEK + S+L E S ++
Sbjct: 7 GYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+F +D H+ A +G++ADAR L + AR EA R +G PL + ++ +T Y
Sbjct: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126
Query: 129 GGVRPFGAALLMA--GVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
VRPFG + ++ VND +LY DPSG + + AIG R A E +MT
Sbjct: 127 SAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMT 186
Query: 187 LDEAIK--LAIFALAKTMEKPSAENIEVAVITVKDKKFRKL----SKEEIEKFLGEVMKE 240
+ +K I + K A +E++ + K ++ +EE EK+ E +KE
Sbjct: 187 CRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDVREEAEKYAKESLKE 246
Query: 241 VEEEE 245
+E +
Sbjct: 247 EDESD 251
>gi|4506183 proteasome (prosome, macropain) subunit, alpha type, 3 [Homo
sapiens] >gi|11434353|ref|XP_007345.1| proteasome
(prosome, macropain) subunit, alpha type, 3 [Homo
sapiens] >gi|130859|sp|P25788|PRC8_HUMAN PROTEASOME
COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C8) >gi|67730|pir||SNHUC8
multicatalytic endopeptidase complex (EC 3.4.99.46)
chain C8 - human >gi|220028|dbj|BAA00659.1| (D00762)
proteasome subunit C8 [Homo sapiens]
Length = 255
Score = 155 bits (387), Expect = 6e-37
Identities = 88/245 (35%), Positives = 134/245 (53%), Gaps = 8/245 (3%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + + FSPDGR+FQV YA +AV+ +TA+G++CKDGVV VEK + S+L E S ++
Sbjct: 7 GYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+F +D H+ A +G++ADAR L + AR EA R +G PL + ++ +T Y
Sbjct: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126
Query: 129 GGVRPFGAALLMA--GVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
VRPFG + ++ VND +LY DPSG + + AIG R A E +MT
Sbjct: 127 SAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMT 186
Query: 187 LDEAIK--LAIFALAKTMEKPSAENIEVA----VITVKDKKFRKLSKEEIEKFLGEVMKE 240
+ +K I + K A +E++ + + + K +EE EK+ E +KE
Sbjct: 187 CRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKE 246
Query: 241 VEEEE 245
+E +
Sbjct: 247 EDESD 251
>emb|CAA62960.1| (X91847) proteasome subunit C9-like protein [Sus scrofa]
Length = 226
Score = 154 bits (386), Expect = 8e-37
Identities = 90/226 (39%), Positives = 143/226 (62%), Gaps = 10/226 (4%)
Query: 41 GVKCKDGVVLAVEKRITSRLIEPESY-EKIFQIDDHIAAASSGIIADARVLVNRARLEAQ 99
G+ DGV+LA E+R +L++ + EKI+++++ +A + +GI +DA VL N RL AQ
Sbjct: 1 GILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQ 60
Query: 100 IHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKP---ELYETDPSG 156
+ L Y EP P +V +CD+KQ +TQ+GG RPFG +LL G DK +LY++DPSG
Sbjct: 61 RYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGW-DKHYGFQLYQSDPSG 119
Query: 157 AYFAWKAVAIGSGRNTAMAIFEDKYRD-DMTLDEAIKLAIFALAKTME--KPSAENIEVA 213
Y WKA IG+ A+++ + Y++ +MTL A+ LAI L KTM+ K SAE +E+A
Sbjct: 120 NYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIA 179
Query: 214 VITVKDKK--FRKLSKEEIEKFLGEVMKEVEEEEVKEKEEDYSELD 257
+T ++ K R L ++E+E+ + + +E + E ++KE++ E D
Sbjct: 180 TLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKD 225
>gi|6755194 proteasome (prosome, macropain) subunit, alpha type 3 [Mus
musculus] >gi|3914438|sp|O70435|PRC8_MOUSE PROTEASOME
COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C8) (PROTEASOME SUBUNIT K)
>gi|3037091|gb|AAC12943.1| (AF055983) proteasome
alpha7/C8 subunit [Mus musculus]
>gi|5757655|gb|AAD50534.1|AF060089_1 (AF060089)
proteasome subunit C8 [Mus musculus]
Length = 255
Score = 154 bits (386), Expect = 8e-37
Identities = 87/245 (35%), Positives = 133/245 (53%), Gaps = 8/245 (3%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + + FSPDGR+FQV YA +AV+ +TA+G++CKDGVV VEK + S+L E S ++
Sbjct: 7 GYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+F +D H+ A +G++ADAR L + AR EA R +G PL + ++ +T Y
Sbjct: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126
Query: 129 GGVRPFGAALLMA--GVNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
VRPFG + ++ ND +LY DPSG + + AIG R A E +MT
Sbjct: 127 SAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMT 186
Query: 187 LDEAIK--LAIFALAKTMEKPSAENIEVAVITVKDKKFRKL----SKEEIEKFLGEVMKE 240
+ +K I + K A +E++ + K ++ +EE EK+ E +KE
Sbjct: 187 CRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDIREEAEKYAKESLKE 246
Query: 241 VEEEE 245
+E +
Sbjct: 247 EDESD 251
>sp|P34066|PRC2_ARATH PROTEASOME, 30 KD SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 30
KD SUBUNIT) >gi|541889|pir||S39900 multicatalytic
endopeptidase complex 30K chain homolog - Arabidopsis
thaliana >gi|166830|gb|AAA16326.1| (M98495) proteasome
[Arabidopsis thaliana] >gi|10177282|dbj|BAB10635.1|
(AB007647) 20S proteasome subunit PAF1 [Arabidopsis
thaliana]
Length = 278
Score = 152 bits (379), Expect = 5e-36
Identities = 95/254 (37%), Positives = 144/254 (56%), Gaps = 9/254 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YD +T +SP GRLFQV YA EAVK+G+ A+G++ + VVLA + S L + KI
Sbjct: 6 YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RKI 63
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
F++DDHI A +G+ AD RVL R E+ H TY P P+ +V + D Q+ TQ
Sbjct: 64 FKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRS 123
Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DMT 186
RP+G LL+ G+++ LY PSG YF ++A AIGS A E ++ D +
Sbjct: 124 WKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSS 183
Query: 187 LDEAIKLAIFALAKTMEKPSAEN--IEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
++ IK AI A+ +T++ + ++ VA++ V D+ F L +E I+K + + ++V EE
Sbjct: 184 REDLIKDAILAVRETLQGETLKSSLCTVAILGV-DEPFHFLDQEAIQKVI-DTFEKVPEE 241
Query: 245 EVKEKEEDYSELDS 258
E E E E ++
Sbjct: 242 EEGEGEAGEGEAEA 255
>gb|AAC32062.1| (AF043526) 20S proteasome subunit PAF1 [Arabidopsis thaliana]
Length = 278
Score = 152 bits (379), Expect = 5e-36
Identities = 95/254 (37%), Positives = 144/254 (56%), Gaps = 9/254 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YD +T +SP GRLFQV YA EAVK+G+ A+G++ + VVLA + S L + KI
Sbjct: 6 YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RKI 63
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
F++DDHI A +G+ AD RVL R E+ H TY P P+ +V + D Q+ TQ
Sbjct: 64 FKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRS 123
Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DMT 186
RP+G LL+ G+++ LY PSG YF ++A AIGS A E ++ D +
Sbjct: 124 WKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSS 183
Query: 187 LDEAIKLAIFALAKTMEKPSAEN--IEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
++ IK AI A+ +T++ + ++ VA++ V D+ F L +E I+K + + ++V EE
Sbjct: 184 REDLIKDAILAVRETLQGETLKSSLCTVAILGV-DEPFHFLDQEAIQKVI-DTFEKVPEE 241
Query: 245 EVKEKEEDYSELDS 258
E E E E ++
Sbjct: 242 EEGEGEAGEGEAEA 255
>gb|AAC32063.1| (AF043527) 20S proteasome subunit PAF2 [Arabidopsis thaliana]
>gi|10092412|gb|AAG12817.1|AC079677_6 (AC079677) 20S
proteasome subunit PAF2; 11103-9423 [Arabidopsis
thaliana]
Length = 277
Score = 152 bits (379), Expect = 5e-36
Identities = 93/243 (38%), Positives = 136/243 (55%), Gaps = 12/243 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YD +T +SP GRLFQV YA EAVK+G+ A+G++ + VVLA + S L + KI
Sbjct: 6 YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RKI 63
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
F++DDHI A +G+ AD RVL R E+ H TY P P+ +V + D Q+ TQ
Sbjct: 64 FKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRS 123
Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDMT 186
RP+G LL+ G+++ LY PSG YF ++A AIGS A E K+ + +
Sbjct: 124 WKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERKFESFQESS 183
Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVK----DKKFRKLSKEEIEKFLGEVMKEVE 242
++ IK AI A+ +T++ E ++ ++ TV D+ F L +E I+K + K E
Sbjct: 184 KEDLIKDAIMAIRETLQ---GETLKSSLCTVSVLGVDEPFHFLDQESIQKVIDTFEKVPE 240
Query: 243 EEE 245
EEE
Sbjct: 241 EEE 243
>pir||T19320 hypothetical protein C15H11.7 - Caenorhabditis elegans
>gi|3874351|emb|CAB02738.1| (Z81035) Similarity to Human
proteasome iota chain (SW:P34062), contains similarity
to Pfam domain: PF00227 (Proteasome A-type and B-type),
Score=132.6, E-value=2.4e-36, N=1~cDNA EST EMBL:T00439
comes from this gene~cDNA EST yk242c6.5 comes from this
g>
Length = 246
Score = 151 bits (378), Expect = 7e-36
Identities = 86/236 (36%), Positives = 138/236 (58%), Gaps = 6/236 (2%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AG+DR IT+FSP+GR++QV YA +A+ TAV VK D V+AV+KR+ LI ++
Sbjct: 7 AGFDRHITIFSPEGRVYQVEYAFKAINSTNLTAVAVKGADAAVIAVQKRVPDSLIVADTV 66
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
++QI + + G+I DA+ + RA+ EA + G P ++ KK+ DL Q +T
Sbjct: 67 TSVYQISQSVGCCAIGMIPDAKFQIKRAQGEAASWKYKNGYDMPCELLAKKMADLNQYYT 126
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKY--R 182
Q +R G ALL +D+ PE+Y DP+G Y K V++G + A + E K +
Sbjct: 127 QNAEMRSLGCALLFISYDDEKGPEVYRVDPAGYYRGMKGVSVGVKQLPATSFLEKKIKKK 186
Query: 183 DDMTLDEAIKLAIFALAKTME-KPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEV 237
++T EAI+LAI AL ++ ++++EV V+T + KF KL+ +++E L ++
Sbjct: 187 SELTSTEAIELAIEALQTSLGIDVRSKDLEVVVVTKDNSKFTKLTSDQVEHHLNQI 242
>sp|O24362|PRC8_SPIOL PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C8)
>gi|7435886|pir||T09139 26S proteasome alpha chain -
spinach >gi|2285802|dbj|BAA21651.1| (D78173) 26S
proteasome alpha subunit [Spinacia oleracea]
Length = 249
Score = 151 bits (377), Expect = 9e-36
Identities = 84/244 (34%), Positives = 130/244 (52%), Gaps = 6/244 (2%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD ++T FSPDGR+FQ+ YA +AV TAVG+KCKDG+VL VEK I S+++ P S +
Sbjct: 7 GYDLSVTTFSPDGRVFQIEYAAKAVDNSGTAVGIKCKDGIVLGVEKLIQSKMMLPGSNRR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I + H A +G+ AD R +V RA+ EA + YGE P+ + ++ + T Y
Sbjct: 67 IHSVHRHSGMAVAGLAADGRQIVARAKSEATNYESVYGEAVPVKELADRVASYVHLCTLY 126
Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
+RPFG +++ G + D P+LY +PSG + + AIG G+ A E +MT
Sbjct: 127 WWLRPFGCGVILGGYDRDGPQLYMVEPSGISYRYFGAAIGKGKQAAKTEIEKLKLSEMTC 186
Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
E I + K ++ + E+ + + D+ SK E +K +++E +
Sbjct: 187 REGIIEVAKIIYKVHDEAKDKAFELEMSWICDE-----SKREHQKVPDNLLQEAKAAATA 241
Query: 248 EKEE 251
EE
Sbjct: 242 ALEE 245
>pir||S38529 multicatalytic endopeptidase complex (EC 3.4.99.46) chain XC8 -
clawed frog
Length = 255
Score = 149 bits (373), Expect = 3e-35
Identities = 84/245 (34%), Positives = 132/245 (53%), Gaps = 8/245 (3%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + + FSPDGR+FQV YA +AV+ +TA+ ++CKDGVV VEK + S+L E S ++
Sbjct: 7 GYDLSASTFSPDGRVFQVEYAAKAVENSSTAISIRCKDGVVFGVEKLVLSKLYEEGSNKR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
IF +D H+ A +G++ADAR L + AR EA R YG PL + ++ +T Y
Sbjct: 67 IFNVDRHVGMAVAGLLADARSLADIAREEASNFRANYGYDIPLKHLSDRVAMYAHAYTLY 126
Query: 129 GGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
VRPFG + ++ N D +LY DPSG + + AIG + A E ++T
Sbjct: 127 SAVRPFGCSFMLGSYNEDDGAQLYMVDPSGISYGYWGCAIGKAKQAAKTEIEKLQMKELT 186
Query: 187 LDEAIK--LAIFALAKTMEKPSAENIEVA----VITVKDKKFRKLSKEEIEKFLGEVMKE 240
+ +K I + K + +E++ + K + K +EE EK+ E ++E
Sbjct: 187 CRDVVKEVAKIIYIVHDEVKDKSFELELSWVGKITNGKHEIVPKDIREEAEKYAKESLEE 246
Query: 241 VEEEE 245
++ +
Sbjct: 247 EDDSD 251
>gb|AAC23597.1| (AF070462) proteasome A type subunit [Cryptosporidium parvum]
Length = 259
Score = 148 bits (370), Expect = 6e-35
Identities = 93/253 (36%), Positives = 147/253 (57%), Gaps = 11/253 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YD + +SP GR+FQ+ YA EAVK+G VG + + VVLA KR TSRL + +K+
Sbjct: 6 YDTDVVTWSPQGRVFQIEYAMEAVKQGTAVVGARNDEIVVLACIKRSTSRLAGYQ--KKL 63
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
++ID+HI A SGI ADA+V+ N R E + TY P PL +V ++ Q++TQ
Sbjct: 64 YKIDNHIGVAVSGITADAKVICNYLRSECLNYSFTYDSPIPLNTLVNRLVLKSQVNTQEY 123
Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DMT 186
G RPFG LL+AG ++ P L+ET PSG F + ++AIGS + E +++ + +
Sbjct: 124 GRRPFGVGLLLAGFDESGPHLFETCPSGNCFEYYSIAIGSRSQASKTYLEKHFKEFANCS 183
Query: 187 LDEAIKLAIFALAKTM---EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
D+ I + AL ++ ++ + EN++VA++ D + +L +EE K+L + +E
Sbjct: 184 KDQLILHTLRALRSSLSSEQEMNQENVDVAILGRND-IYNELLEEEKIKYLQIINQEQPP 242
Query: 244 --EEVKEKEEDYS 254
E++ E +E S
Sbjct: 243 TIEQINESQETSS 255
>gb|AAB48404.1| (U73851) 29 kDa proteasome subunit TCPR29 [Trypanosoma cruzi]
>gi|1857249|gb|AAB48405.1| (U75302) TCPR29 [Trypanosoma
cruzi]
Length = 265
Score = 148 bits (369), Expect = 8e-35
Identities = 103/262 (39%), Positives = 138/262 (52%), Gaps = 18/262 (6%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
YD T +SP GRLFQV YA EAV G+ AVG K KD VVL KR S + + SY EK
Sbjct: 6 YDTNTTTWSPTGRLFQVEYANEAVNNGSAAVGAKNKDFVVLTALKR--SPVAQFSSYQEK 63
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+F++DDH+ A +G++AD R+L R E +R + PL +I + + + Q H Q+
Sbjct: 64 VFKLDDHVGMAIAGLVADGRMLARFVRTECMNYRYMHDSDNPLPLIAEIVGEKYQRHIQF 123
Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DM 185
G RPFG LL+AG + P LY T PSG F +KA A+G A E + D
Sbjct: 124 AGKRPFGVGLLIAGYDSTGPHLYHTVPSGDVFDFKATAMGLRSQAARTYLEKHFESFPDC 183
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITV--KDKKFRKLSKEEIEKFL-GEVMK--- 239
LDE I A+ ALA + NI+ I + K F L++E K+L G M+
Sbjct: 184 GLDELIMHALKALAAATSGGAELNIKNTTIAIVGKGTPFMVLTEEAARKYLDGFKMRPED 243
Query: 240 -----EVEEEE-VKEKEEDYSE 255
E EEEE ++E+ D E
Sbjct: 244 IPPAPEAEEEETLQERSLDVEE 265
>gb|AAB48403.1| (U73850) 29 kDa proteasome subunit TCPR29A [Trypanosoma cruzi]
Length = 265
Score = 148 bits (369), Expect = 8e-35
Identities = 103/262 (39%), Positives = 138/262 (52%), Gaps = 18/262 (6%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
YD T +SP GRLFQV YA EAV G+ AVG K KD VVL KR S + + SY EK
Sbjct: 6 YDTNTTTWSPTGRLFQVEYANEAVNNGSAAVGTKNKDFVVLTALKR--SPVAQFSSYQEK 63
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+F++DDH+ A +G++AD R+L R E +R + PL +I + + + Q H Q+
Sbjct: 64 VFKLDDHVGMAIAGLVADGRMLARFVRTECMNYRYMHDSDNPLPLIAEIVGEKYQRHIQF 123
Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DM 185
G RPFG LL+AG + P LY T PSG F +KA A+G A E + D
Sbjct: 124 AGKRPFGVGLLIAGYDSTGPHLYHTVPSGDVFDFKATAMGLRSQAARTYLEKHFESFPDC 183
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITV--KDKKFRKLSKEEIEKFL-GEVMK--- 239
LDE I A+ ALA + NI+ I + K F L++E K+L G M+
Sbjct: 184 GLDELIMHALKALAAATSGGAELNIKNTTIAIVGKGTPFMVLTEEAARKYLDGFKMRPED 243
Query: 240 -----EVEEEE-VKEKEEDYSE 255
E EEEE ++E+ D E
Sbjct: 244 IPPAPEAEEEETLQERSLDVEE 265
>pir||T41139 proteasome component c1 - fission yeast (Schizosaccharomyces pombe)
>gi|3080509|emb|CAA18639.1| (AL022598) proteasome
component c1 [Schizosaccharomyces pombe]
Length = 253
Score = 147 bits (368), Expect = 1e-34
Identities = 80/210 (38%), Positives = 120/210 (57%), Gaps = 2/210 (0%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + FSPDGRLFQ YA +AV+ +T +G+KC+DGV+LA+EK +TS+L++P +
Sbjct: 7 GYDLGL-FFSPDGRLFQAEYAYKAVENASTCIGIKCEDGVILALEKVVTSKLLKPRVNNR 65
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I +D HI A++G I D + +V RAR EA R YG P P VI ++ + Q+ T Y
Sbjct: 66 IGSVDRHIGIATTGFIPDGQHIVKRARDEATSWRDNYGSPIPGTVIADRLGNYVQLFTCY 125
Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
VRPFG +A + + P LY +P+G Y+ + A G GR A E + +
Sbjct: 126 SSVRPFGVMSFVATYDSEGPHLYMVEPNGVYWGYNGAAAGKGRQVARNELEKLNFSSLKM 185
Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITV 217
+A+K A L T ++ + + E+ + V
Sbjct: 186 KDAVKEAARILYATHDEENNKEHEIEMTWV 215
>gb|AAC32064.1| (AF043528) 20S proteasome subunit PAG1 [Arabidopsis thaliana]
>gi|3885332|gb|AAC77860.1| (AC005623) 20S proteasome
subunit C8 (PAG1/PRC8_ARATH) [Arabidopsis thaliana]
Length = 249
Score = 147 bits (367), Expect = 1e-34
Identities = 79/244 (32%), Positives = 132/244 (53%), Gaps = 6/244 (2%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD ++T FSPDGR+FQ+ YA +AV T VG+KCKDG+V+ VEK I S+++ P S +
Sbjct: 7 GYDLSVTTFSPDGRVFQIEYAAKAVDNSGTVVGIKCKDGIVMGVEKLIASKMMLPGSNRR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I + H A +G+ AD R +V RA+ EA+ + YG+ P+ + +++ + T Y
Sbjct: 67 IHSVHRHAGMAVAGLAADGRQIVARAKSEARSYESVYGDAVPVKELSERVASYVHLCTLY 126
Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
+RPFG +++ G + D P+LY +PSG + + AIG G+ A E +MT
Sbjct: 127 WWLRPFGCGVILGGYDRDGPQLYMIEPSGISYRYFGAAIGKGKQAAKTEIEKLNLSEMTC 186
Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
E + + K ++ + E+ + + ++ SK E +K ++++E +
Sbjct: 187 KEGVIEVAKIIYKLHDEAKDKAFELEMSWICEE-----SKREHQKVPDDLLEEAKTAAKT 241
Query: 248 EKEE 251
EE
Sbjct: 242 ALEE 245
>emb|CAA73625.1| (Y13182) multicatalytic endopeptidase [Arabidopsis thaliana]
Length = 267
Score = 146 bits (366), Expect = 2e-34
Identities = 91/238 (38%), Positives = 133/238 (55%), Gaps = 12/238 (5%)
Query: 15 TVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIFQIDD 74
T +SP GRLFQV YA EAVK+G+ A+G++ + VVLA + S L + KIF++DD
Sbjct: 1 TTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RKIFKVDD 58
Query: 75 HIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPF 134
HI A +G+ AD RVL R E+ H TY P P+ +V + D Q+ TQ RP+
Sbjct: 59 HIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRSWKRPY 118
Query: 135 GAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDMTLDEAI 191
G LL+ G+++ LY PSG YF ++A AIGS A E K+ + + ++ I
Sbjct: 119 GVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERKFESFQESSKEDLI 178
Query: 192 KLAIFALAKTMEKPSAENIEVAVITVK----DKKFRKLSKEEIEKFLGEVMKEVEEEE 245
K AI A+ +T++ E ++ ++ TV D+ F L +E I+K + K EEEE
Sbjct: 179 KDAIMAIRETLQ---GETLKSSLCTVSVLGVDEPFHFLDQESIQKVIDTFEKVPEEEE 233
>dbj|BAA96833.1| (AB026562) alpha 7 subunit of 20S proteasome [Oryza sativa]
Length = 249
Score = 145 bits (361), Expect = 7e-34
Identities = 80/245 (32%), Positives = 131/245 (52%), Gaps = 3/245 (1%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD ++T FSPDGR+FQV YA +AV T VG+KCKDG+VL VEK +TS+++ S +
Sbjct: 7 GYDLSVTTFSPDGRVFQVEYATKAVDNSGTVVGIKCKDGIVLGVEKLVTSKMMLEGSNRR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I + H A +G+ AD R +V+RA+ EA + YGEP + + ++ + T Y
Sbjct: 67 IHSVHWHSGLAVAGLAADGRQIVSRAKSEAASYEKVYGEPISVKELADRVASYVHLCTLY 126
Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
+RPFG +++ G + D P+LY +PSG + + A+G GR A E ++T
Sbjct: 127 WWLRPFGCGVILGGYDRDGPQLYMIEPSGVSYKYFGAALGKGRQAAKTEIEKLKLSELTC 186
Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
E I + ++ + E+ + + D+ R+ +++ L E K + ++
Sbjct: 187 REGIVEVAKIIYGVHDEAKDKAFELELSWICDESNRQ--HQKVPADLLEQAKVAAQAALE 244
Query: 248 EKEED 252
E + D
Sbjct: 245 EMDAD 249
>sp|O23715|PRC8_ARATH PROTEASOME COMPONENT C8 (MACROPAIN SUBUNIT C8) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C8)
>gi|2511592|emb|CAA74027.1| (Y13693) multicatalytic
endopeptidase complex, proteasome component, alpha
subunit [Arabidopsis thaliana]
Length = 249
Score = 144 bits (360), Expect = 9e-34
Identities = 78/244 (31%), Positives = 131/244 (52%), Gaps = 6/244 (2%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD ++T FSPDG +FQ+ YA +AV T VG+KCKDG+V+ VEK I S+++ P S +
Sbjct: 7 GYDLSVTTFSPDGGVFQIEYAAKAVDNSGTVVGIKCKDGIVMGVEKLIASKMMLPGSNRR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
I + H A +G+ AD R +V RA+ EA+ + YG+ P+ + +++ + T Y
Sbjct: 67 IHSVHRHAGMAVAGLAADGRQIVARAKSEARSYESVYGDAVPVKELSERVASYVHLCTLY 126
Query: 129 GGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTL 187
+RPFG +++ G + D P+LY +PSG + + AIG G+ A E +MT
Sbjct: 127 WWLRPFGCGVILGGYDRDGPQLYMIEPSGISYRYFGAAIGKGKQAAKTEIEKLNLSEMTC 186
Query: 188 DEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
E + + K ++ + E+ + + ++ SK E +K ++++E +
Sbjct: 187 KEGVIEVAKIIYKLHDEAKDKAFELEMSWICEE-----SKREHQKVPDDLLEEAKTAAKT 241
Query: 248 EKEE 251
EE
Sbjct: 242 ALEE 245
>gb|AAD52094.1|AF088882_1 (AF088882) 20S proteasome alpha subunit [Leishmania donovani]
Length = 250
Score = 142 bits (355), Expect = 3e-33
Identities = 83/244 (34%), Positives = 132/244 (54%), Gaps = 13/244 (5%)
Query: 7 QAGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPES 65
+AG+D+ ITVFSP+G L+QV YA +AV G + ++CKD V++A + I RL+ P+S
Sbjct: 3 RAGFDKYITVFSPEGSLYQVEYAFKAVTYPGLLTIAIRCKDAVLVATQHVIPDRLMRPDS 62
Query: 66 YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
++++ I +G D R LV RAR EA + YG P+AV+ K++ D Q+
Sbjct: 63 VTALYEVTPSIGCCMTGRAPDGRALVQRAREEASDYHYRYGVQIPIAVLAKRMGDKAQVR 122
Query: 126 TQYGGVRPFGAALLMAGVND-------KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE 178
TQ G+RP G G++ KP++Y DP+G A A+G + AMA E
Sbjct: 123 TQQAGLRPMGVVSTFIGMDQSDQDGSLKPQIYTVDPAGWTGGHIACAVGKKQVEAMAFLE 182
Query: 179 DKYR----DDMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKF 233
+ + D++T EA +A+ AL + A+ +EV T + F+++ E+E++
Sbjct: 183 KRQKSTKFDELTQKEAAMIALAALQSAIGTAVKAKEVEVGRCTAANPAFQRVPNSEVEEW 242
Query: 234 LGEV 237
L V
Sbjct: 243 LTAV 246
>emb|CAA10314.1| (AJ131148) proteasome subunit alpha-6 [Trypanosoma brucei
rhodesiense]
Length = 266
Score = 141 bits (352), Expect = 8e-33
Identities = 98/254 (38%), Positives = 130/254 (50%), Gaps = 9/254 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESY-EK 68
YD T +SP GRLFQV YA EAV G+ AVGVK D VVL KR + + SY EK
Sbjct: 6 YDTDTTTWSPTGRLFQVEYANEAVNNGSAAVGVKGADYVVLTALKR--NPVSGLSSYQEK 63
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
F++D+H+ A SG++AD R L R E +R + APL ++ + Q H Q+
Sbjct: 64 AFKLDEHVGMAISGLVADGRALSRFLRTECMNYRYMHDSDAPLVMLADIVGAKHQRHIQF 123
Query: 129 GGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDM 185
G RPFG LL+AG + + P LY+T PSG F +KA A+G A E +R
Sbjct: 124 AGKRPFGVGLLIAGYDRQGPRLYQTVPSGDVFDFKATAMGLRSQAARTYLERHFRGFPAC 183
Query: 186 TLDEAIKLAIFALAKTMEKPSAENIEVAVITV--KDKKFRKLSKEEIEKFLGEVMKEVEE 243
LDE + A+ AL NI+ I + K F L++EE K+L E+
Sbjct: 184 DLDELVMHALRALGAATSGGVELNIKNTTIAIVGKGTPFTILTEEEARKYLDGFKTRPED 243
Query: 244 -EEVKEKEEDYSEL 256
V + EED EL
Sbjct: 244 IPAVADNEEDDDEL 257
>sp|P52428|PRC2_ORYSA PROTEASOME COMPONENT C2 (MACROPAIN SUBUNIT C2) (MULTICATALYTIC
ENDOPEPTIDASE COMPLEX SUBUNIT C2)
>gi|7435884|pir||T03925 probable multicatalytic
endopeptidase complex (EC 3.4.99.46) chain C2 - rice
>gi|1066151|dbj|BAA07128.1| (D37886) proteasome C2
subunit [Oryza sativa]
Length = 270
Score = 141 bits (351), Expect = 1e-32
Identities = 88/250 (35%), Positives = 136/250 (54%), Gaps = 12/250 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YD +T +SP GRLFQV YA EAVK+G+ VG++ + VLA + S L + K+
Sbjct: 6 YDTDVTTWSPAGRLFQVEYAMEAVKQGSACVGLRSRTHAVLAAANKAASELSSHQ--RKV 63
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
F++ DH A +G+ AD RVL R E H Y P P++ + ++ D Q+ TQ
Sbjct: 64 FRVADHAGVALAGLTADGRVLSRFLRSECINHAFVYDAPLPVSRLALRLADKAQVCTQRS 123
Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDMT 186
RP+G LL+AG+++ LY PSG YF ++A AIGS A E ++ +D T
Sbjct: 124 WKRPYGVGLLVAGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTFLERRFEGYNDYT 183
Query: 187 LDEAIKLAIFALAKTM--EKPSAENIEVAVITVKD----KKFRKLSKEEIEKFLGEVMKE 240
++ IK A+ A+ +T+ EK ++ N VA++ KD + F + + I++ + + M+
Sbjct: 184 PEQLIKDALSAIKETLQGEKLTSSNCTVAIVGRKDDGTVEPFEMIDVKRIQEII-DSMEA 242
Query: 241 VEEEEVKEKE 250
EE E E
Sbjct: 243 AEEAPAAEAE 252
>gb|AAC34197.1| (AF017650) testes-specific alpha4 proteasome subunit [Drosophila
virilis]
Length = 245
Score = 140 bits (350), Expect = 1e-32
Identities = 91/240 (37%), Positives = 138/240 (56%), Gaps = 9/240 (3%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
+D ++ ++S DG L QV YA+EAV++G+T VG++ K+ VVL VEKR L + KI
Sbjct: 4 FDESVNIYS-DGHLLQVEYAQEAVRKGST-VGLRTKECVVLGVEKRAIDSLQIERTSRKI 61
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
+ID H+A +G+ ADARVLV+RA++EAQ HRL + PA + I + + LKQ +TQ
Sbjct: 62 KKIDQHMAMTFAGLTADARVLVSRAQVEAQSHRLNFDRPASVEYITRYLARLKQTYTQSV 121
Query: 130 GVRPFGAALLMAGVND--KPELYETDPSGAYFAWKAVAIGS-GRNTAMAIFEDKYRDDMT 186
RPFG + L+ G ++ +P L++TDPSG Y+ W A G G+ + ++ T
Sbjct: 122 ARRPFGVSCLIGGFDEDGRPRLFQTDPSGIYYEWSANTTGRLGQTVNEYLEKNTAAISRT 181
Query: 187 LD--EAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEE 244
D A+K + AL T +IE+AV+ + + E +E LG + +E EE
Sbjct: 182 PDAASAMKHVVRALF-TATSLDPASIELAVLRYW-QPIEMVKPETLEYLLGVIKQEAVEE 239
>gb|AAF69728.1|AC068783_4 (AC068783) 26S Proteasome alpha subunit [Leishmania major]
Length = 250
Score = 140 bits (350), Expect = 1e-32
Identities = 83/244 (34%), Positives = 131/244 (53%), Gaps = 13/244 (5%)
Query: 7 QAGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPES 65
+AG+D+ ITVFSP+G L+QV YA +AV G V ++CKD V++A + I RL+ P+S
Sbjct: 3 RAGFDKYITVFSPEGSLYQVEYAFKAVTYPGLLTVAIRCKDAVLVATQHVIPDRLMRPDS 62
Query: 66 YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
++++ I +G D R LV RAR EA + YG P+AV+ K++ D Q+
Sbjct: 63 VTMLYEVTPGIGCCMTGRAPDGRALVQRAREEASDYHYRYGVQIPIAVLAKRMGDKAQVR 122
Query: 126 TQYGGVRPFGAALLMAGVND-------KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFE 178
TQ G+RP G G++ KP++Y DP+G A A+G + AMA E
Sbjct: 123 TQQAGLRPMGVVSTFIGMDQSDQDGALKPQIYTVDPAGWTCGHIACAVGKKQVEAMAFLE 182
Query: 179 DKYRD----DMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKF 233
+ + ++T EA +A+ AL + A+ +EV T + F+++ E+E++
Sbjct: 183 KRQKSTEFAELTQKEAAMIALAALQSAIGTAVKAKEVEVGRCTAANPAFQRVPNSEVEEW 242
Query: 234 LGEV 237
L V
Sbjct: 243 LTAV 246
>gb|AAF58889.1| (AE003832) Prosalpha7 gene product [Drosophila melanogaster]
Length = 253
Score = 140 bits (349), Expect = 2e-32
Identities = 79/217 (36%), Positives = 127/217 (58%), Gaps = 15/217 (6%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + + FSPDGR+FQ++YA +AV++ T +G++ KD VVLAVEK ITS+L EP++ +
Sbjct: 7 GYDLSASQFSPDGRVFQIDYASKAVEKSGTVIGIRGKDAVVLAVEKIITSKLYEPDAGGR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
IF I+ +I A +G++AD + + AR EA +R + + PL + ++ +T Y
Sbjct: 67 IFTIEKNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLY 126
Query: 129 GGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
VRPFG ++++A + + P+LY+ +PSG+ F + A A G + A E K + DM
Sbjct: 127 SAVRPFGLSIILASWDEVEGPQLYKIEPSGSSFGYFACASGKAKQLAKTEME-KLKMDMR 185
Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFR 223
DE ++ A + K ++ +KDK FR
Sbjct: 186 TDELVESAGEIIYKVHDE------------LKDKDFR 210
>pir||T40592 26s proteasome alpha subunit - fission yeast (Schizosaccharomyces
pombe) >gi|4160352|emb|CAA22820.1| (AL035216) 26s
proteasome alpha subunit [Schizosaccharomyces pombe]
Length = 244
Score = 139 bits (347), Expect = 3e-32
Identities = 82/239 (34%), Positives = 133/239 (55%), Gaps = 8/239 (3%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
G+DR ITVFSP+GRL+QV YA +A G T+VGV K+ + +K++ +LI+ + +
Sbjct: 6 GFDRTITVFSPEGRLYQVEYAFKAFNNAGITSVGVTGKNCACVISQKKVPDKLIDASTVK 65
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
+F I I +G IADAR V+RAR EA G P P V+ K++ ++ Q+ TQ
Sbjct: 66 HVFPITKGIGCVMTGSIADARAQVSRARSEAAEFEYKNGYPMPCDVLAKRMANIAQVSTQ 125
Query: 128 YGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDD- 184
+RP G A+ + V+D+ P L++ DP+G Y +KA + G + + E +++ D
Sbjct: 126 RAAMRPLGVAMTLVAVDDEIGPSLFKLDPAGFYIGYKATSAGPKQTETINWLEKRFKKDG 185
Query: 185 --MTLDEAIKLAIFALAKTMEKP-SAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
L + ++ I AL ++ + +++ V+ DK FR LS EEIE L + ++
Sbjct: 186 IPSNLTDTVETGIQALMSSLSTDFKSTELQIGVVE-DDKPFRVLSVEEIEAHLQSIAEK 243
>gb|AAF89683.1|AF169651_1 (AF169651) 20S proteasome alpha 7 subunit [Trypanosoma brucei]
Length = 237
Score = 138 bits (344), Expect = 7e-32
Identities = 78/217 (35%), Positives = 122/217 (55%), Gaps = 1/217 (0%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYE 67
+G+D++ +FS DGR+FQV YA +AV G+TAV CKDGVV+AVEK +TSR++E S
Sbjct: 4 SGHDQSTDIFSADGRVFQVEYACKAVDNGSTAVAACCKDGVVVAVEKILTSRMLEEGSNN 63
Query: 68 KIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQ 127
+I +D G++ D +V+RAR EA+ R + P +++ +I + ++T
Sbjct: 64 RIHAVDRQAGICVCGVLPDGLAVVSRARGEAENSRDIFSTPILGSLLASRIGEFMHVYTT 123
Query: 128 YGGVRPFGAALLMAG-VNDKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
+ RPFG ++++A +D P+LY DPSGA + +A+G G+ A E +T
Sbjct: 124 HYAYRPFGCSVIIASYADDGPQLYVADPSGAVAGYYGIALGKGKTVAKTELEKLDFATLT 183
Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFR 223
EA++ L + +K + EV V V DK R
Sbjct: 184 CSEAVEKLTNILHEVHDKSKDKIYEVEVAWVCDKSDR 220
>gb|AAB03506.1| (U60168) PrtC [Dictyostelium discoideum]
Length = 248
Score = 136 bits (340), Expect = 2e-31
Identities = 83/239 (34%), Positives = 135/239 (55%), Gaps = 12/239 (5%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK- 68
YD IT FSP GR+ Q+ YA EAVK+G AV +K K VL KR +S L SY+K
Sbjct: 6 YDSDITTFSPSGRIHQIEYAMEAVKQGGAAVALKSKQFAVLVSLKRSSSEL---GSYQKK 62
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
IF +DDH+ A SG+ ADAR+L N R E + Y + +V K+ D Q+HTQ
Sbjct: 63 IFVVDDHVGIAISGLTADARMLCNYMRNECSNYNYVYESQMRVERLVTKVADKHQVHTQR 122
Query: 129 GGVRPFGAALLMAGVND-KPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR--DDM 185
G RP+G LL+AG + +Y+T PSG ++ +K+++IGS +A E + ++
Sbjct: 123 YGRRPYGVGLLVAGYDQLGAHIYQTCPSGNFYDYKSISIGSRSQSAKTYLEKHFESFEEC 182
Query: 186 TLDEAIKLAIFALAKTM----EKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
TL++ I + AL +T+ + +++N+ + ++ + + F+ + + + + +L + E
Sbjct: 183 TLEQLITHGLRALRETIPNTDDTLNSKNVSIGIVG-EGQPFKIIEEADAQPYLNLLENE 240
>gb|AAC16604.1| (AF027978) 20S proteasome subunit C2 [Gallus gallus]
Length = 260
Score = 133 bits (331), Expect = 2e-30
Identities = 84/235 (35%), Positives = 131/235 (55%), Gaps = 11/235 (4%)
Query: 6 PQAGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPES 65
P AG D +TV+SP GR+ Q+ YA EAVK+G+ VG+K K VL KR S L +
Sbjct: 3 PVAGSD--VTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ- 59
Query: 66 YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
+KI +D+HI + +G+ ADAR+L N R E R + P P++ +V I Q+
Sbjct: 60 -KKILYVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIP 118
Query: 126 TQYGGVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD- 183
TQ G RP+G LL+AG +D P +++T PS YF KA++IG+ +A E +
Sbjct: 119 TQRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCKAMSIGARSQSARNYLERHMTEF 178
Query: 184 -DMTLDEAIKLAIFALAKTM---EKPSAENIEVAVITVKDKKFRKLSKEEIEKFL 234
D L+E +K + AL +T+ + + +N+ + ++ KD +F +++ FL
Sbjct: 179 TDCNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVG-KDMEFTIYDDDDVAPFL 232
>pir||S64739 multicatalytic endopeptidase complex (EC 3.4.99.46) chain XC9
(clone 2) - clawed frog (fragment)
Length = 194
Score = 132 bits (329), Expect = 4e-30
Identities = 80/188 (42%), Positives = 118/188 (62%), Gaps = 13/188 (6%)
Query: 72 IDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGV 131
++D +A + +GI +DA VL N RL AQ + L Y EP P +V +CD+KQ +TQ+GG
Sbjct: 1 LNDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGK 60
Query: 132 RPFGAALLMAGVNDKP---ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD-DMTL 187
RPFG +LL G DK +LY++DPSG Y WKA IG+ A+++ + Y++ +MTL
Sbjct: 61 RPFGVSLLYIGW-DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTL 119
Query: 188 DEAIKLAIFALAKTME--KPSAENIEVAVITVKD--KKFRKLSKEEIEKFLGEVMKEVEE 243
A+ LA+ L KTM+ K SAE +E+A +T ++ K R L ++E+E E++K EE
Sbjct: 120 KSALALAVKVLNKTMDVSKLSAEKVELATLTRENGKTKIRVLKQKEVE----ELIKLHEE 175
Query: 244 EEVKEKEE 251
EE K + E
Sbjct: 176 EEAKIERE 183
>gb|AAG28527.1|AF198386_1 (AF198386) 20S proteasome alpha 1 subunit [Trypanosoma brucei]
Length = 266
Score = 130 bits (323), Expect = 2e-29
Identities = 80/246 (32%), Positives = 133/246 (53%), Gaps = 14/246 (5%)
Query: 7 QAGYDRAITVFSPDGRLFQVNYAREAVK-RGATAVGVKCKDGVVLAVEKRITSRLIEPES 65
+AG+D+ ITVFSP+G L+QV YA +AV G V ++CKD V++ + + +L+ PE+
Sbjct: 3 RAGFDKYITVFSPEGSLYQVEYAFKAVTYAGLLTVAIRCKDAVLVFTQHSVPDKLMRPET 62
Query: 66 YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
++ ++D+ +G D + LV +AR EA ++ YG P ++V+ K D+ Q+
Sbjct: 63 ITSLYNVNDNTGVCITGRAPDGKALVQKARNEASEYKYRYGMPMLVSVLAKPWQDMAQVR 122
Query: 126 TQYGGVRPFGAALLMAGV--NDK-----PELYETDPSGAYFAWKAVAIGSGRNTAMAIFE 178
TQ G+R G + G+ ND+ P++Y DP+G A A A+G + A A E
Sbjct: 123 TQQAGMRLMGTIMTFVGMEQNDEDGAWIPQIYCVDPAGG-AAVHACAVGKKQIEACAFLE 181
Query: 179 DKYRD----DMTLDEAIKLAIFALAKTM-EKPSAENIEVAVITVKDKKFRKLSKEEIEKF 233
K ++ ++ EA +A+ AL + E A +EV T D F ++S E++K+
Sbjct: 182 KKQKNAPFHTLSQKEAAMIALAALQSALGESLRASGVEVGRCTADDHHFLRVSDREVKKW 241
Query: 234 LGEVMK 239
L + K
Sbjct: 242 LTPLAK 247
>gi|6321427 Proteasome subunit YC7alpha/Y8 (protease yscE subunit 7); Scl1p
[Saccharomyces cerevisiae]
>gi|130858|sp|P21243|PRCI_YEAST PROTEASOME COMPONENT
C7-ALPHA (MACROPAIN SUBUNIT C7-ALPHA) (PROTEINASE YSCE
SUBUNIT 7) (MULTICATALYTIC ENDOPEPTIDASE COMPLEX C7)
(COMPONENT Y8) (SCL1 SUPPRESSOR PROTEIN)
>gi|67728|pir||SNBYS1 multicatalytic endopeptidase
complex (EC 3.4.99.46) chain YC7-alpha - yeast
(Saccharomyces cerevisiae) >gi|11513998|pdb|1G0U|G Chain
G, A Gated Channel Into The Proteasome Core Particle
>gi|11514012|pdb|1G0U|U Chain U, A Gated Channel Into
The Proteasome Core Particle >gi|172266|gb|AAA34909.1|
(M63641) proteasome Y8 [Saccharomyces cerevisiae]
>gi|173206|gb|AAA35228.1| (M55440) yeast proteasome
subunit YC7-alpha [Saccharomyces cerevisiae]
>gi|506484|emb|CAA40056.1| (X56732) proteasome Y8
subunit [Saccharomyces cerevisiae]
>gi|1322467|emb|CAA96711.1| (Z72533) ORF YGL011c
[Saccharomyces cerevisiae]
>gi|4261594|gb|AAD13894.1|S58126_111 (S58126) Unknown
[Saccharomyces cerevisiae] >gi|5734547|emb|CAA40292.1|
(X56971) proteasome subunit YC7-alpha [Saccharomyces
cerevisiae] >gi|227817|prf||1712124A proteasome PRS2
[Saccharomyces cerevisiae]
Length = 252
Score = 128 bits (318), Expect = 7e-29
Identities = 84/244 (34%), Positives = 132/244 (53%), Gaps = 13/244 (5%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AGYDR IT+FSP+GRL+QV YA +A + ++ V+ KD V+ +K++ +L++P +
Sbjct: 10 AGYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTV 69
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
IF I I +G I DAR RA+ EA R YG P V+ K++ +L Q++T
Sbjct: 70 SYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYT 129
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR-- 182
Q +RP G L V+++ P +Y+TDP+G Y +KA A G + E+ ++
Sbjct: 130 QRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKS 189
Query: 183 --DDMTLDEAIKLAIFALAKTMEKPSAE----NIEVAVITVKDKKFRKLSKEEIEKFLGE 236
D + + K+ FA+ ++ E ++EV V T KD KF LS E IE+ L
Sbjct: 190 KIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVAT-KD-KFFTLSAENIEERLVA 247
Query: 237 VMKE 240
+ ++
Sbjct: 248 IAEQ 251
>pdb|1G65|G Chain G, Crystal Structure Of Epoxomicin:20s Proteasome Reveals A
Molecular Basis For Selectivity Of
Alpha,Beta-Epoxyketone Proteasome Inhibitors
>gi|11513433|pdb|1G65|U Chain U, Crystal Structure Of
Epoxomicin:20s Proteasome Reveals A Molecular Basis For
Selectivity Of Alpha,Beta-Epoxyketone Proteasome
Inhibitors >gi|3114269|pdb|1RYP|A Chain A, Crystal
Structure Of The 20s Proteasome From Yeast At 2.4
Angstroms Resolution >gi|3114283|pdb|1RYP|O Chain O,
Crystal Structure Of The 20s Proteasome From Yeast At
2.4 Angstroms Resolution
Length = 243
Score = 128 bits (318), Expect = 7e-29
Identities = 84/244 (34%), Positives = 132/244 (53%), Gaps = 13/244 (5%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESY 66
AGYDR IT+FSP+GRL+QV YA +A + ++ V+ KD V+ +K++ +L++P +
Sbjct: 1 AGYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTV 60
Query: 67 EKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHT 126
IF I I +G I DAR RA+ EA R YG P V+ K++ +L Q++T
Sbjct: 61 SYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYT 120
Query: 127 QYGGVRPFGAALLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR-- 182
Q +RP G L V+++ P +Y+TDP+G Y +KA A G + E+ ++
Sbjct: 121 QRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKS 180
Query: 183 --DDMTLDEAIKLAIFALAKTMEKPSAE----NIEVAVITVKDKKFRKLSKEEIEKFLGE 236
D + + K+ FA+ ++ E ++EV V T KD KF LS E IE+ L
Sbjct: 181 KIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVAT-KD-KFFTLSAENIEERLVA 238
Query: 237 VMKE 240
+ ++
Sbjct: 239 IAEQ 242
>sp|P12881|PRC2_DROME PROTEASOME 29 KDA SUBUNIT (MULTICATALYTIC ENDOPEPTIDASE COMPLEX 35
KDA SUBUNIT) >gi|67724|pir||SNFF5K multicatalytic
endopeptidase complex (EC 3.4.99.46) 35K chain - fruit
fly (Drosophila melanogaster) >gi|8382|emb|CAA33520.1|
(X15497) 35 kd proteasome subunit (AA 1 - 279)
[Drosophila melanogaster] >gi|8388|emb|CAA44173.1|
(X62285) 35 KDa proteasome subunit [Drosophila
melanogaster] >gi|7297622|gb|AAF52875.1| (AE003627)
Pros35 gene product [Drosophila melanogaster]
Length = 279
Score = 126 bits (313), Expect = 3e-28
Identities = 86/251 (34%), Positives = 132/251 (52%), Gaps = 11/251 (4%)
Query: 10 YDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEKI 69
YD +TV+SP GRL QV YA EAVK G VG+K KD VL + TS L ++ KI
Sbjct: 6 YDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSEL--SDTQRKI 63
Query: 70 FQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYG 129
IDDH+ + +G+ ADARVL R E ++ +Y P++ ++ + + Q TQ
Sbjct: 64 IPIDDHLGISIAGLTADARVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTTQRY 123
Query: 130 GVRPFGAALLMAGVNDK-PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD--DMT 186
RP+G LL+AG +++ P +Y+ PS +F KA +IGS +A E D +
Sbjct: 124 DRRPYGVGLLVAGYDERGPHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSS 183
Query: 187 LDEAIKLAIFALAKTM----EKPSAENIEVAVITV-KDKKFRKLSKEEIEKFLGEVMKEV 241
DE I+ I A+ T+ + A ++ V V KD+ F LS ++ K + + KE
Sbjct: 184 KDEIIRHGIRAILGTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDSAKHVA-IAKEN 242
Query: 242 EEEEVKEKEED 252
+ + + ++D
Sbjct: 243 DNDTPRNDDDD 253
>gb|AAB82572.1| (AF025793) 20S proteasome alpha7 subunit [Drosophila melanogaster]
Length = 249
Score = 126 bits (313), Expect = 3e-28
Identities = 83/246 (33%), Positives = 134/246 (53%), Gaps = 19/246 (7%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD + + FS DGR+FQ++YA + K G T +G++ KD VVLAVEK ITS+L EP + +
Sbjct: 7 GYDLSASQFSADGRVFQIDYASKVEKSG-TVIGIRGKDAVVLAVEKIITSKLYEPHAGGR 65
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
IF I+ +I A +G++AD + + AR EA +R + + PL + ++ +T Y
Sbjct: 66 IFTIEKNIGMAVAGLVADGNFVADIARQEAANYRQQFEQAIPLKHLCHRVAGYVHAYTLY 125
Query: 129 GGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
VRPFG ++++A + + P+LY+ +PSG+ F + A A + A E K + DM
Sbjct: 126 SAVRPFGLSIILASWDEVEGPQLYKIEPSGSSFGYFACA-SKAKQLAKTEME-KLKTDMR 183
Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEV 246
DE ++ A + K ++ +KDK FR + + G + + E+
Sbjct: 184 TDELVESAGEIIYKVHDE------------LKDKDFR-FEMGLVGRVTGG-LHLINPSEL 229
Query: 247 KEKEED 252
EK+ED
Sbjct: 230 TEKDED 235
>pir||T18511 hypothetical protein C0745c - malaria parasite (Plasmodium
falciparum) >gi|3758867|emb|CAB11152.1| (Z98551)
proteasome component C8 [Plasmodium falciparum]
Length = 252
Score = 117 bits (291), Expect = 1e-25
Identities = 69/245 (28%), Positives = 133/245 (54%), Gaps = 9/245 (3%)
Query: 8 AGYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAV--EKRITSRLIEPES 65
AGYD +++ FSPDGRL+QV Y +++ TA+ ++CKDG++ +++I+ S
Sbjct: 6 AGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNS 65
Query: 66 YEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMH 125
Y +I+ ++++I SG DAR +++RAR EA + + PL ++V +I +
Sbjct: 66 YNRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAY 125
Query: 126 TQYGGVRPFGAALLMAGVN--DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRD 183
T Y +RPF A+++++ N DK ++Y +P+GA + + + IG + E K
Sbjct: 126 TLYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYK 185
Query: 184 DMTLDEAIK-LAIFALAKT--MEKPSAENIEVAVITVKDK--KFRKLSKEEIEKFLGEVM 238
D+ + +AI+ + F L M K + +N+ K+ +F+ + +E + L + +
Sbjct: 186 DINVRDAIEDIYKFILTSDDHMNKNNLQNLVNFSWICKESSYEFQNIHEEILTPALNKAV 245
Query: 239 KEVEE 243
+ +E+
Sbjct: 246 EYIEK 250
>sp|Q09583|PRC8_CAEEL PUTATIVE PROTEASOME COMPONENT ZK945.2 (MACROPAIN SUBUNIT)
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT)
>gi|7511433|pir||T28119 hypothetical protein ZK945.2 -
Caenorhabditis elegans >gi|3881887|emb|CAA88436.1|
(Z48544) contains similarity to Pfam domain: PF00227
(Proteasome A-type and B-type), Score=200.0,
E-value=1.2e-56, N=1~cDNA EST yk162f6.3 comes from this
gene~cDNA EST yk162f6.5 comes from this gene~cDNA EST
yk404c9.3 comes from this gene~cDNA EST yk40>
Length = 260
Score = 115 bits (285), Expect = 6e-25
Identities = 71/237 (29%), Positives = 122/237 (50%), Gaps = 8/237 (3%)
Query: 9 GYDRAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPESYEK 68
GYD A + FSPDGR+FQV YA++AV T + ++ K+GVV+ +K I+S+L + +
Sbjct: 7 GYDLAASTFSPDGRIFQVEYAQKAVDNAGTMIAIRGKNGVVVVADKLISSKLYTDNANPR 66
Query: 69 IFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQY 128
+F ++D++ A +G D L N A EA Y EP P+ I + + +HT
Sbjct: 67 MFNVNDNVGVAVAGNYPDGFALKNYAYGEAMKWLKDYREPMPIQNIANSVAEYIHIHT-L 125
Query: 129 GGVRPFGAALLMAGVNDKP--ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMT 186
G RPFGA N + L+ +PSG + +KA A+G R A A E +++
Sbjct: 126 GISRPFGAGAFFMSWNKQTGGRLFLVEPSGLNYEYKAWAVGKHRQAAKAEIEKLKIEELD 185
Query: 187 LDEAIKLAIFALAKTMEKPSAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEE 243
+++ +K A + ++ +N+++ + V ++ + + E+ EV+ EE
Sbjct: 186 VNQLVKEAARIIMVVRDENKDKNVQIEMGWVGEQ-----TNGKYEEVPSEVVTAAEE 237
>gi|11498092 proteasome, subunit beta (psmB) [Archaeoglobus fulgidus]
>gi|6093784|sp|O29769|PRCB_ARCFU PROTEASOME BETA SUBUNIT
(MULTICATALYTIC ENDOPEPTIDASE COMPLEX BETA SUBUNIT)
>gi|7435875|pir||A69310 proteasome, subunit beta (psmB)
homolog - Archaeoglobus fulgidus
>gi|2650155|gb|AAB90757.1| (AE001071) proteasome,
subunit beta (psmB) [Archaeoglobus fulgidus]
Length = 213
Score = 113 bits (280), Expect = 2e-24
Identities = 66/212 (31%), Positives = 116/212 (54%), Gaps = 7/212 (3%)
Query: 31 EAVKRGATAVGVKCKDGVVLAVEKRIT-SRLIEPESYEKIFQIDDHIAAASSGIIADARV 89
E + +G T VG+ CKDGVV+A EKR T I ++ +KI+QI D +A ++G + DA+
Sbjct: 6 EKIYKGTTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQF 65
Query: 90 LVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKPE- 148
L ++EA ++ + + I +L + + P+ LL+ G++ + +
Sbjct: 66 LARIIKIEANLYEIRRERKPTVRAIATLTSNLLNSYRYF----PYLVQLLIGGIDSEGKS 121
Query: 149 LYETDPSGAYFAWK-AVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKPSA 207
+Y DP G K VA GSG TA + ED++ ++ +DEA++LA+ A+ M++ SA
Sbjct: 122 IYSIDPIGGAIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSA 181
Query: 208 ENIEVAVITVKDKKFRKLSKEEIEKFLGEVMK 239
+ V+ + + +F + S EE+E+ L + K
Sbjct: 182 SGDGIDVVKITEDEFYQYSPEEVEQILAKFRK 213
>gb|AAA35020.1| (M31430) scll+ suppressor protein [Saccharomyces cerevisiae]
Length = 270
Score = 101 bits (248), Expect = 1e-20
Identities = 72/233 (30%), Positives = 119/233 (50%), Gaps = 13/233 (5%)
Query: 19 PDGRLFQVNYAREAVKR-GATAVGVKCKDGVVLAVEKRITSRLIEPESYEKIFQIDDHIA 77
P ++QV YA +A + ++ V+ KD V+ +K++ +L++P + IF I I
Sbjct: 39 PPRVVYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSYIFCISRTIG 98
Query: 78 AASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAA 137
+G I DAR RA+ EA R YG P V+ K++ +L Q++TQ +RP G
Sbjct: 99 MVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVI 158
Query: 138 LLMAGVNDK--PELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYR----DDMTLDEAI 191
L V+++ P +Y+TDP+G Y +KA A G + E+ ++ D + +
Sbjct: 159 LTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWE 218
Query: 192 KLAIFALAKTMEKPSAE----NIEVAVITVKDKKFRKLSKEEIEKFLGEVMKE 240
K+ FA+ ++ E ++EV V T KD KF LS E IE+ L + ++
Sbjct: 219 KVVEFAITHMIDALGTEFSKNDLEVGVAT-KD-KFFTLSAENIEERLVAIAEQ 269
>sp|Q58634|PRCB_METJA PROTEASOME BETA SUBUNIT PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX BETA SUBUNIT) >gi|2129223|pir||D64454 proteasome
beta subunit homolog - Methanococcus jannaschii
>gi|1591869|gb|AAB99241.1| (U67564) proteasome, subunit
beta (psmB) [Methanococcus jannaschii]
Length = 224
Score = 97.1 bits (238), Expect = 2e-19
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 18/224 (8%)
Query: 33 VKRGATAVGVKCKDGVVLAVEKRIT-SRLIEPESYEKIFQIDDHIAAASSGIIADARVLV 91
V +G T VG+ C D V+LA +KR + L+ + +K+++IDD+IA +G + DA+ +V
Sbjct: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62
Query: 92 NRARLEAQIHRLTYGE---PAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVN--DK 146
EA+++++ G P A ++ I +M PF +++ G + +
Sbjct: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF-------PFLTQIIIGGYDLLEG 115
Query: 147 PELYETDPSGAYFAWKA-VAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKP 205
+L+ DP G K A GSG A + E Y DM+++E IKLA+ AL ME+
Sbjct: 116 AKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERD 175
Query: 206 --SAENIEVAVITVKDKKFRKLSKEEIEKFLGEVMKEVEEEEVK 247
S I +AVIT K EEIEK L + + +++ K
Sbjct: 176 TFSGNGISLAVITKDGVKI--FEDEEIEKILDSMKAKPKKKTTK 217
>gi|6755206 proteasome (prosome, macropain) subunit, beta type 7 [Mus musculus]
>gi|7435873|pir||JC6122 proteasome beta-type Z chain (EC
3.4.-.-) - mouse >gi|1632755|dbj|BAA12017.1| (D83585)
proteasome Z subunit precursor [Mus musculus]
>gi|2062107|emb|CAA71824.1| (Y10874) proteasome subunti
MC14 [Mus musculus] >gi|2547068|dbj|BAA22857.1| (D85570)
PSMB7 [Mus musculus]
Length = 277
Score = 95.6 bits (234), Expect = 5e-19
Identities = 81/244 (33%), Positives = 118/244 (48%), Gaps = 21/244 (8%)
Query: 31 EAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEKIFQIDDHIAAASSGIIADARV 89
+A K G T GV KDG+VL + R T ++ + + KI I +I +G AD +
Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97
Query: 90 LVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVN-DKPE 148
++H LT G P V ++ LKQM +Y G GAAL++ GV+ P
Sbjct: 98 TTQLISSNLELHSLTTGR-LPRVVTANRM--LKQMLFRYQGY--IGAALVLGGVDVTGPH 152
Query: 149 LYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTM--EKPS 206
LY P G+ V +GSG AMA+FEDK+R DM +EA KL A+A + + S
Sbjct: 153 LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGS 212
Query: 207 AENIEVAVI-----------TVKDKKFRKLSKEEIEKFLGEVMKE-VEEEEVKEKEEDYS 254
NI++ VI +V +KK +L + EK V+ E V E++ EE
Sbjct: 213 GSNIDLCVISKSKLDFLRPFSVPNKKGTRLGRYRCEKGTTAVLTEKVTPLEIEVLEETVQ 272
Query: 255 ELDS 258
+D+
Sbjct: 273 TMDT 276
>gi|4506203 proteasome (prosome, macropain) subunit, beta type, 7; Z [Homo
sapiens] >gi|11428779|ref|XP_005463.1| proteasome
(prosome, macropain) subunit, beta type, 7 [Homo
sapiens] >gi|1531533|dbj|BAA07238.1| (D38048) proteasome
subunit z [Homo sapiens]
Length = 277
Score = 92.4 bits (226), Expect = 5e-18
Identities = 78/241 (32%), Positives = 115/241 (47%), Gaps = 21/241 (8%)
Query: 34 KRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEKIFQIDDHIAAASSGIIADARVLVN 92
K G T GV KDG+VL + R T ++ + + KI I +I +G AD +
Sbjct: 41 KTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQ 100
Query: 93 RARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVN-DKPELYE 151
++H L+ G P V ++ LKQM +Y G GAAL++ GV+ P LY
Sbjct: 101 LISSNLELHSLSTGR-LPRVVTANRM--LKQMLFRYQGY--IGAALVLGGVDVTGPHLYS 155
Query: 152 TDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTM--EKPSAEN 209
P G+ V +GSG AMA+FEDK+R DM +EA L A+A + + S N
Sbjct: 156 IYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSN 215
Query: 210 IEVAVI-----------TVKDKKFRKLSKEEIEKFLGEVMKE-VEEEEVKEKEEDYSELD 257
I++ VI TV +KK +L + EK V+ E + E++ EE +D
Sbjct: 216 IDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMD 275
Query: 258 S 258
+
Sbjct: 276 T 276
>gb|AAF97811.1|AF285103_1 (AF285103) proteasome z subunit [Rattus norvegicus]
Length = 277
Score = 92.4 bits (226), Expect = 5e-18
Identities = 80/244 (32%), Positives = 117/244 (47%), Gaps = 21/244 (8%)
Query: 31 EAVKRGATAVGVKCKDGVVLAVEKRITSRLIEPE-SYEKIFQIDDHIAAASSGIIADARV 89
+A K G T GV KDG+VL + R T ++ + + KI I +I +G AD +
Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97
Query: 90 LVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVN-DKPE 148
++H LT G P V ++ LKQM +Y G GAAL++ GV+ P
Sbjct: 98 TTQLISSNLELHSLTTGR-LPRVVTANRM--LKQMLFRYQGY--IGAALVLGGVDVTGPH 152
Query: 149 LYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTM--EKPS 206
LY P G+ V +GSG AMA+FEDK+R DM +EA KL A+A + + S
Sbjct: 153 LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGS 212
Query: 207 AENIEVAVI-----------TVKDKKFRKLSKEEIEKFLGEVMKE-VEEEEVKEKEEDYS 254
NI++ VI +V +KK + + EK V+ E V E++ EE
Sbjct: 213 GSNIDLCVISKSKLDFLRPYSVPNKKGTRFGRYRCEKGTTAVLTEKVTPLELEVLEEIVQ 272
Query: 255 ELDS 258
+D+
Sbjct: 273 TMDT 276
>emb|CAB57537.1| (Y18930) proteasome, beta subunit [Sulfolobus solfataricus]
Length = 225
Score = 84.7 bits (206), Expect = 1e-15
Identities = 56/207 (27%), Positives = 99/207 (47%), Gaps = 10/207 (4%)
Query: 33 VKRGATAVGVKCKDGVVLAVEKRITSRL-IEPESYEKIFQIDDHIAAASSGIIADARVLV 91
+ +G T VG++ DGV+LA ++R ++ + + K+ I D I ++G +AD + +
Sbjct: 28 ILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIY 87
Query: 92 NRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKPELYE 151
+ + + +T P + I ++ ++ + P+ +L+ G +D+P L+
Sbjct: 88 DVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYF----PYIVQILIGGYDDQPRLFN 143
Query: 152 TDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKPSAENIE 211
D G VA GSG AM + ED+Y MTLDEA LA A+ +++ S
Sbjct: 144 LDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTG 203
Query: 212 VAVITVKDKKFRKLSKEEIEKFLGEVM 238
V V + K EE+E +L + M
Sbjct: 204 VIVAKIHSK-----GHEELEFYLNKKM 225
>sp|Q9UXF3|PRCB_SULSO PROTEASOME BETA SUBUNIT PRECURSOR (MULTICATALYTIC ENDOPEPTIDASE
COMPLEX BETA SUBUNIT)
Length = 208
Score = 84.7 bits (206), Expect = 1e-15
Identities = 56/207 (27%), Positives = 99/207 (47%), Gaps = 10/207 (4%)
Query: 33 VKRGATAVGVKCKDGVVLAVEKRITSRL-IEPESYEKIFQIDDHIAAASSGIIADARVLV 91
+ +G T VG++ DGV+LA ++R ++ + + K+ I D I ++G +AD + +
Sbjct: 11 ILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIY 70
Query: 92 NRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKPELYE 151
+ + + +T P + I ++ ++ + P+ +L+ G +D+P L+
Sbjct: 71 DVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYF----PYIVQILIGGYDDQPRLFN 126
Query: 152 TDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKPSAENIE 211
D G VA GSG AM + ED+Y MTLDEA LA A+ +++ S
Sbjct: 127 LDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTG 186
Query: 212 VAVITVKDKKFRKLSKEEIEKFLGEVM 238
V V + K EE+E +L + M
Sbjct: 187 VIVAKIHSK-----GHEELEFYLNKKM 208
>emb|CAA73621.1| (Y13178) multicatalytic endopeptidase [Arabidopsis thaliana]
Length = 273
Score = 82.7 bits (201), Expect = 4e-15
Identities = 63/227 (27%), Positives = 110/227 (47%), Gaps = 18/227 (7%)
Query: 4 VPPQAGYD----RAITVFSPDGRLFQVNYAREAVKRGATAVGVKCKDGVVLAVEKRITSR 59
VPP+ G+ + + +P G A +K G T VG+ KDGV+L + R T
Sbjct: 8 VPPKGGFSFDLCKRNDMLTPKGLK-----APSFLKTGTTIVGLIFKDGVILGADTRATEG 62
Query: 60 -LIEPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKI 118
++ ++ EKI + +I +G AD + + + ++HR G + ++ +
Sbjct: 63 PIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTDMVSSQLRLHRYQTGRDSR---VITAL 119
Query: 119 CDLKQMHTQYGGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIF 177
LK+ Y G AAL++ GV+ P L+ P G+ +GSG AM++F
Sbjct: 120 TLLKKHLFSYQG--HVSAALVLGGVDITGPHLHTIYPHGSTDTLPFATMGSGSLAAMSVF 177
Query: 178 EDKYRDDMTLDEAIKLAIFALAKTM--EKPSAENIEVAVITVKDKKF 222
E KY++ +T DE IKL ++ + + S N+++ VIT +K++
Sbjct: 178 EAKYKEGLTRDEGIKLVAESICSGIFNDLGSGSNVDICVITKGNKEY 224
>gb|AAC32067.1| (AF043531) 20S proteasome beta subunit PBB2 [Arabidopsis thaliana]
>gi|9758084|dbj|BAB08528.1| (AB009052) 20S proteasome
beta subunit PBB2 [Arabidopsis thaliana]
Length = 274
Score = 82.7 bits (201), Expect = 4e-15
Identities = 64/224 (28%), Positives = 109/224 (48%), Gaps = 12/224 (5%)
Query: 4 VPPQAGYDRAITVFSPDGRLFQVNY-AREAVKRGATAVGVKCKDGVVLAVEKRITSR-LI 61
+PP+ G+ + + + L Q A +K G T VG+ KDGV+L + R T ++
Sbjct: 8 IPPKGGF--SFDLCKRNDMLTQKGLKAPSFLKTGTTIVGLIFKDGVILGADTRATEGPIV 65
Query: 62 EPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDL 121
++ EKI + +I +G AD + + + ++HR G + +V + L
Sbjct: 66 ADKNCEKIHYMAPNIYCCGAGTAADTEAVTDMVSSQLRLHRYQTGRDSR---VVTALTLL 122
Query: 122 KQMHTQYGGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
K+ Y G AAL++ GV+ P L+ P G+ +GSG AM++FE K
Sbjct: 123 KKHLFSYQG--HVSAALVLGGVDITGPHLHTIYPHGSTDTLPFATMGSGSLAAMSVFEAK 180
Query: 181 YRDDMTLDEAIKLAIFALAKTM--EKPSAENIEVAVITVKDKKF 222
Y++ +T DE IKL A+ + + S N+++ VIT K++
Sbjct: 181 YKEGLTRDEGIKLVAEAICSGIFNDLGSGSNVDICVITKGHKEY 224
>gb|AAC32066.1| (AF043530) 20S proteasome beta subunit PBB1 [Arabidopsis thaliana]
>gi|7939516|dbj|BAA95719.1| (AB024028) 20S proteasome
beta subunit / multicatalytic endopeptidase [Arabidopsis
thaliana]
Length = 273
Score = 82.3 bits (200), Expect = 5e-15
Identities = 63/224 (28%), Positives = 110/224 (48%), Gaps = 12/224 (5%)
Query: 4 VPPQAGYDRAITVFSPDGRLFQVNY-AREAVKRGATAVGVKCKDGVVLAVEKRITSR-LI 61
VPP+ G+ + + + L Q A +K G T VG+ KDGV+L + R T ++
Sbjct: 8 VPPKGGF--SFDLCKRNDMLTQKGLKAPSFLKTGTTIVGLIFKDGVILGADTRATEGPIV 65
Query: 62 EPESYEKIFQIDDHIAAASSGIIADARVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDL 121
++ EKI + +I +G AD + + + ++HR G + ++ + L
Sbjct: 66 ADKNCEKIHYMAPNIYCCGAGTAADTEAVTDMVSSQLRLHRYQTGRDSR---VITALTLL 122
Query: 122 KQMHTQYGGVRPFGAALLMAGVN-DKPELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDK 180
K+ Y G AAL++ GV+ P L+ P G+ +GSG AM++FE K
Sbjct: 123 KKHLFSYQG--HVSAALVLGGVDITGPHLHTIYPHGSTDTLPFATMGSGSLAAMSVFEAK 180
Query: 181 YRDDMTLDEAIKLAIFALAKTM--EKPSAENIEVAVITVKDKKF 222
Y++ +T DE IKL ++ + + S N+++ VIT +K++
Sbjct: 181 YKEGLTRDEGIKLVAESICSGIFNDLGSGSNVDICVITKGNKEY 224
>dbj|BAA19767.1| (D89725) LMP7 [Oryzias latipes]
Length = 225
Score = 78.0 bits (189), Expect = 1e-13
Identities = 51/212 (24%), Positives = 97/212 (45%), Gaps = 4/212 (1%)
Query: 29 AREAVKRGATAVGVKCKDGVVLAVEKRI-TSRLIEPESYEKIFQIDDHIAAASSGIIADA 87
AR + G T + K K GV++AV+ R T I Y K+ +I+ ++ SG AD
Sbjct: 14 ARFELHHGTTTLSFKFKHGVIVAVDSRASTGSYIATCEYNKVIEINPYLLGTMSGSAADC 73
Query: 88 RVLVNRARLEAQIHRLTYGEPAPLAVIVKKICDLKQMHTQYGGVRPFGAALLMAGVNDKP 147
+ E +++RL +A K +C+ M Y G+ +++ + P
Sbjct: 74 KYWERLLAKECRLYRLRNNHRISVAAASKLLCN---MMLGYRGMGLSVGSMICGWDKEGP 130
Query: 148 ELYETDPSGAYFAWKAVAIGSGRNTAMAIFEDKYRDDMTLDEAIKLAIFALAKTMEKPSA 207
+Y D +G + + + GSG N A + + Y++DMT++EA +L + + S
Sbjct: 131 GIYYVDDNGNRLSGRMFSTGSGSNYAYGVLDSGYKEDMTVEEAYELGRRGIVHATHRDSY 190
Query: 208 ENIEVAVITVKDKKFRKLSKEEIEKFLGEVMK 239
V + +++ + K+ K+++ + L K
Sbjct: 191 SGGVVNMYHIQEDGWIKVCKDDVSELLHHYKK 222
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.134 0.372
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91647362
Number of Sequences: 2977
Number of extensions: 3661577
Number of successful extensions: 24760
Number of sequences better than 1.0e-10: 217
Number of HSP's better than 0.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 24218
Number of HSP's gapped (non-prelim): 233
length of query: 260
length of database: 189,106,746
effective HSP length: 59
effective length of query: 201
effective length of database: 153,796,013
effective search space: 30912998613
effective search space used: 30912998613
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 164 (68.3 bits)