BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0420 (rph) DE:ribonuclease PH (rph)
         (249 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||E75181 ribonuclease ph (rph) PAB0420 - Pyrococcus abyssi (s...   491  e-138
pir||E71032 hypothetical protein PH1549 - Pyrococcus horikoshii ...   478  e-134
emb|CAC12415.1| (AL445067) RNase PH (yeast SIK6) related protein...   306  2e-82
gb|AAK41031.1| Ribonuclease PH (rph) [Sulfolobus solfataricus]        305  4e-82
emb|CAB57569.1| (Y18930) ribonuclease PH [Sulfolobus solfataricus]    305  4e-82
pir||A69191 tRNA nucleotidyltransferase (EC 2.7.7.56) - Methanob...   298  5e-80
gi|11498104 ribonuclease PH (rph) [Archaeoglobus fulgidus] >gi|7...   297  9e-80
pir||G72623 probable ribonuclease PH APE1447 - Aeropyrum pernix ...   272  3e-72
pir||T47954 exonuclease RRP41 [imported] - Arabidopsis thaliana ...   207  9e-53
gi|9506689 hypothetical protein [Homo sapiens] >gi|7020801|dbj|B...   183  2e-45
gb|AAF53263.1| (AE003639) CG15481 gene product [Drosophila melan...   148  7e-35
sp|Q17533|RNPH_CAEEL RIBONUCLEASE PH-LIKE PROTEIN B0564.1 >gi|38...   141  1e-32
pir||T11740 hypothetical protein - fission yeast (Schizosaccharo...   126  2e-28
pir||T11646 tRNA nucleotidyltransferase homolog - fission yeast ...   126  2e-28
gi|6321634 homolog of RNAse PH; Ski6p [Saccharomyces cerevisiae]...   115  5e-25
pir||E70320 polyribonucleotide nucleotidyltransferase - Aquifex ...   100  3e-20
sp|O67069|RNPH_AQUAE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY...    99  3e-20
pir||D82978 ribonuclease PH PA5334 [imported] - Pseudomonas aeru...    99  4e-20
sp|P03842|RNPH_ECOLI RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY...    94  1e-18
sp|P50597|RNPH_PSEAE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY...    94  2e-18
sp|P44444|RNPH_HAEIN RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY...    93  3e-18
pir||QQECPE tRNA nucleotidyltransferase (EC 2.7.7.56) - Escheric...    92  4e-18
pir||A72264 polynucleotide phosphorylase - Thermotoga maritima (...    92  8e-18
emb|CAB06341.1| (Z84207) polynucleotide phosphorylase [Thermus t...    91  1e-17
gb|AAF72714.1|AF263927_2 (AF263927) ribonuclease PH [Carnobacter...    91  1e-17
gb|AAA61996.1| (L10328) RNase PH [Escherichia coli] >gi|1790074|...    89  7e-17
sp|P28619|RNPH_BACSU RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY...    88  1e-16
sp|Q10628|RNPH_MYCTU PROBABLE RIBONUCLEASE PH (RNASE PH) (TRNA N...    88  1e-16
sp|O87792|PNP_PSEPU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P...    87  1e-16
pir||C83052 polyribonucleotide nucleotidyltransferase PA4740 [im...    87  1e-16
dbj|BAB06787.1| (AP001517) ribonuclease PH [Bacillus halodurans]       87  2e-16
pir||A44914 tRNA nucleotidyltransferase (EC 2.7.7.56) - Bacillus...    87  3e-16
pir||G81332 polyribonucleotide nucleotidyltransferase (EC 2.7.7....    86  4e-16
sp|P37939|RNPH_MYCLE PROBABLE RIBONUCLEASE PH (RNASE PH) (TRNA N...    85  6e-16
sp|P50849|PNPA_BACSU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (...    85  1e-15
sp|P57454|PNP_BUCAI POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P...    85  1e-15
dbj|BAB06126.1| (AP001515) polynucleotide phosphorylase [Bacillu...    84  1e-15
pir||S74509 polyribonucleotide nucleotidyltransferase (EC 2.7.7....    83  4e-15
pir||T36127 probable ribonuclease PH - Streptomyces coelicolor >...    83  4e-15
pir||D70200 polyribonucleotide nucleotidyltransferase (pnpA) hom...    81  1e-14
pir||D82350 ribonuclease PH VC0210 [imported] - Vibrio cholerae ...    81  1e-14
pir||H65106 polyribonucleotide nucleotidyltransferase (EC 2.7.7....    81  1e-14
gb|AAA57967.1| (U18997) polynucleotide phosphorylase [Escherichi...    80  2e-14
sp|P05055|PNP_ECOLI POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P...    80  2e-14
emb|CAA71697.1| (Y10692) pnp [Yersinia enterocolitica]                 80  2e-14
sp|O34275|PNP_YEREN POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P...    80  2e-14
gi|9910360 exosome component Rrp46 [Homo sapiens] >gi|11424056|r...    80  2e-14
sp|Q9ZD43|PNP_RICPR POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P...    80  3e-14
pir||A81866 tRNA nucleotidyltransferase (EC 2.7.7.56) - Neisseri...    80  3e-14
sp|P41121|PNP_PHOLU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P...    79  4e-14
pir||G81076 ribonuclease PH NMB1499 [imported] - Neisseria menin...    79  4e-14
pir||T49262 hypothetical protein F12M12.180 - Arabidopsis thalia...    79  4e-14
prf||2208281A 100RNP protein [Spinacia oleracea]                       79  6e-14
gb|AAC49669.1| (U52048) polyribonucleotide phophorylase [Spinaci...    79  6e-14
pir||S64680 exoribonuclease 100 RNP - spinach                          79  6e-14
pir||G75320 polynucleotide phosphorylase - Deinococcus radiodura...    79  6e-14
pir||C82673 ribonuclease PH XF1505 [imported] - Xylella fastidio...    77  2e-13
pir||A26118 polyribonucleotide nucleotidyltransferase (EC 2.7.7....    77  2e-13
pir||E82298 polyribonucleotide nucleotidyltransferase VC0647 [im...    77  2e-13
pir||C71269 probable polyribonucleotide nucleotidyltransferase (...    76  3e-13
pir||H69190 conserved hypothetical protein MTH682 - Methanobacte...    76  4e-13
pir||G81725 polyribonucleotide nucleotidyltransferase TC0230 [im...    75  6e-13
pir||F82831 polynucleotide phosphorylase XF0239 [imported] - Xyl...    75  6e-13
sp|P44584|PNP_HAEIN POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P...    75  6e-13
sp|Q9ZCT5|RNPH_RICPR RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY...    75  6e-13
pir||T48631 polynucleotide phosphorylase - Arabidopsis thaliana ...    75  8e-13
pir||T50343 low homolog to ribonuclease ph-like protein [importe...    75  8e-13
gb|AAD28218.1|AF120720_1 (AF120720) ribonuclease PH [Legionella ...    75  1e-12
gb|AAF68421.1|AF237935_1 (AF237935) polynucleotide phosphorylase...    75  1e-12
pir||B75378 ribonuclease PH - Deinococcus radiodurans (strain R1...    74  2e-12
emb|CAA20272.1| (AL031231) guanosine pentaphosphate synthetase/ ...    73  2e-12
pir||T10932 polyribonucleotide nucleotidyltransferase (EC 2.7.7....    73  2e-12
pdb|1E3P|A Chain A, Tungstate Derivative Of Streptomyces Antibio...    73  2e-12
pir||T44900 probable polyribonucleotide nucleotidyltransferase (...    73  3e-12
gb|AAF00646.1|AC009540_23 (AC009540) putative polynucleotide pho...    73  4e-12
emb|CAB85703.1| (AJ252123) putative polynucleotide phosphorylase...    73  4e-12
gb|AAB17498.1| (U19858) guanosine pentaphosphate synthetase [Str...    72  5e-12
pir||F70883 probable guanosine pentaphosphate synthetase and pol...    72  5e-12
pdb|1E3H|A Chain A, Semet Derivative Of Streptomyces Antibioticu...    72  5e-12
pir||E71463 probable polyribonucleotide nucleotidyltransferase -...    71  1e-11
pir||T06540 polyribonucleotide nucleotidyltransferase (EC 2.7.7....    71  2e-11
pir||H81943 probable polyribonucleotide nucleotidyltransferase (...    71  2e-11
pir||E64671 polynucleotide phosphorylase - Helicobacter pylori (...    69  4e-11
pir||G72009 polyribonucleotide nucleotidyltransferase CP0855 [im...    69  4e-11
pir||E71845 polyribonucleotide nucleotidyltransferase - Helicoba...    68  8e-11
pir||C81161 polyribonucleotide nucleotidyltransferase NMB0758 [i...    68  8e-11

>pir||E75181 ribonuclease ph (rph) PAB0420 - Pyrococcus abyssi (strain Orsay)
           >gi|5458042|emb|CAB49532.1| (AJ248284) ribonuclease PH
           (rph) [Pyrococcus abyssi]
           Length = 249
           
 Score =  491 bits (1251), Expect = e-138
 Identities = 249/249 (100%), Positives = 249/249 (100%)

Query: 1   MMEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPR 60
           MMEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPR
Sbjct: 1   MMEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPR 60

Query: 61  ELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR 120
           ELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR
Sbjct: 61  ELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR 120

Query: 121 TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED 180
           TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED
Sbjct: 121 TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED 180

Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK 240
           NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK
Sbjct: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK 240

Query: 241 IAQEVEGSE 249
           IAQEVEGSE
Sbjct: 241 IAQEVEGSE 249


>pir||E71032 hypothetical protein PH1549 - Pyrococcus horikoshii
           >gi|3257978|dbj|BAA30661.1| (AP000006) 249aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 249
           
 Score =  478 bits (1218), Expect = e-134
 Identities = 242/249 (97%), Positives = 247/249 (99%)

Query: 1   MMEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPR 60
           MMEKPEGLKLIDENGRRIDGRKKYELRPIKM+VGVLKNANGSAYIEWG+NKIIAAVYGPR
Sbjct: 1   MMEKPEGLKLIDENGRRIDGRKKYELRPIKMKVGVLKNANGSAYIEWGRNKIIAAVYGPR 60

Query: 61  ELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR 120
           ELH KHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR
Sbjct: 61  ELHSKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR 120

Query: 121 TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED 180
           T+IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED
Sbjct: 121 TSIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED 180

Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK 240
           NYGEADVPVAIMPLKNDITLLQMDGYLTK+EFIEAV+LAIKGAKAVYQKQREALKEKYLK
Sbjct: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKEEFIEAVRLAIKGAKAVYQKQREALKEKYLK 240

Query: 241 IAQEVEGSE 249
           IAQEVE SE
Sbjct: 241 IAQEVEESE 249


>emb|CAC12415.1| (AL445067) RNase PH (yeast SIK6) related protein [Thermoplasma
           acidophilum]
           Length = 248
           
 Score =  306 bits (775), Expect = 2e-82
 Identities = 148/240 (61%), Positives = 189/240 (78%), Gaps = 1/240 (0%)

Query: 8   LKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL 67
           +KLI+E+  R+DGR   ELRPIK++ GVL  A+GSAYIEWG NKI+  VYGP+E +PKH 
Sbjct: 9   IKLINEDNLRLDGRSFNELRPIKIQAGVLNRADGSAYIEWGGNKIMVGVYGPKEAYPKHS 68

Query: 68  QRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFI 127
           Q  D AI++ RYNMA FSV+ERK+PGPDRR++EISKVI  AL  ++++E FPR  IDV+I
Sbjct: 69  QDIDHAIVKARYNMAAFSVDERKRPGPDRRTMEISKVISEALSSSIMIEQFPRAEIDVYI 128

Query: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADV 187
           EVLQADAGTR+AG+TAA++ALADAG+PMRD+V  C AGK++G +VLDL+KEEDNYGEAD+
Sbjct: 129 EVLQADAGTRIAGLTAATVALADAGVPMRDMVVGCTAGKVDGHMVLDLSKEEDNYGEADI 188

Query: 188 PVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQEVEG 247
           P+AIMP   DI L+QMDG +T+DE  +A+ +  +  K + Q QREAL  KY KI    EG
Sbjct: 189 PIAIMPKTGDIVLMQMDGDVTEDELYQAMDMIFEATKRISQIQREALLNKY-KIQDIGEG 247


>gb|AAK41031.1| Ribonuclease PH (rph) [Sulfolobus solfataricus]
           Length = 248
           
 Score =  305 bits (772), Expect = 4e-82
 Identities = 148/243 (60%), Positives = 191/243 (77%), Gaps = 3/243 (1%)

Query: 2   MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRE 61
           +E+P   KLI ++G+R DGRK  ELR IK+E+GVLKNA+GSA  E G  K IAAVYGP+E
Sbjct: 7   VERP---KLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKE 63

Query: 62  LHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRT 121
           +HP+HL  PDRA+LRVRY+M PFS +ERK P P RR IE+SKVI+ ALE A+++E+FPRT
Sbjct: 64  MHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRT 123

Query: 122 AIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDN 181
           AIDVF E+LQADAG+R+  + AASLALADAGIPMRDL+A  A GK +G I+LDLN+ ED 
Sbjct: 124 AIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDM 183

Query: 182 YGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKI 241
           +GEAD+P+A+MP  N +TL Q++G +T DEF +A  LA+KG   +Y  +REALK KY++ 
Sbjct: 184 WGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEF 243

Query: 242 AQE 244
            +E
Sbjct: 244 KEE 246


>emb|CAB57569.1| (Y18930) ribonuclease PH [Sulfolobus solfataricus]
           Length = 248
           
 Score =  305 bits (772), Expect = 4e-82
 Identities = 148/243 (60%), Positives = 191/243 (77%), Gaps = 3/243 (1%)

Query: 2   MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRE 61
           +E+P   KLI ++G+R DGRK  ELR IK+E+GVLKNA+GSA  E G  K IAAVYGP+E
Sbjct: 7   VERP---KLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKE 63

Query: 62  LHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRT 121
           +HP+HL  PDRA+LRVRY+M PFS +ERK P P RR IE+SKVI+ ALE A+++E+FPRT
Sbjct: 64  MHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRT 123

Query: 122 AIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDN 181
           AIDVF E+LQADAG+R+  + AASLALADAGIPMRDL+A  A GK +G I+LDLN+ ED 
Sbjct: 124 AIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDM 183

Query: 182 YGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKI 241
           +GEAD+P+A+MP  N +TL Q++G +T DEF +A  LA+KG   +Y  +REALK KY++ 
Sbjct: 184 WGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEF 243

Query: 242 AQE 244
            +E
Sbjct: 244 KEE 246


>pir||A69191 tRNA nucleotidyltransferase (EC 2.7.7.56) - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621768|gb|AAB85188.1| (AE000848) ribonuclease PH
           [Methanobacterium thermoautotrophicum]
           Length = 240
           
 Score =  298 bits (754), Expect = 5e-80
 Identities = 144/222 (64%), Positives = 183/222 (81%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R DGR   ELRP+K+E G+L+ A+GS+Y+E+G NKI+ AVYGPRE   + LQRPDRA++R
Sbjct: 17  REDGRAFDELRPLKIEAGILERADGSSYLEFGGNKILVAVYGPREAQIRKLQRPDRAVIR 76

Query: 77  VRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGT 136
            RYNMAPFSVEERK+PGPDRRS+EISK+   AL PALILE FPR+ IDVFIEVL+A+ GT
Sbjct: 77  CRYNMAPFSVEERKRPGPDRRSVEISKITAEALRPALILEKFPRSVIDVFIEVLEAEGGT 136

Query: 137 RVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADVPVAIMPLKN 196
           R AGITAAS+ALADAGIPMRD+V ACAAGK+  ++VLDL++EED  G+ADVPVAI+P   
Sbjct: 137 RCAGITAASVALADAGIPMRDMVVACAAGKVGDQVVLDLSEEEDKEGQADVPVAILPRTR 196

Query: 197 DITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKY 238
           +ITLLQ DG LT +EF  A+ LA++G   +++ Q+EAL+++Y
Sbjct: 197 EITLLQSDGNLTPEEFERALDLAVEGCLRIHEVQKEALRKRY 238


>gi|11498104 ribonuclease PH (rph) [Archaeoglobus fulgidus]
           >gi|7435296|pir||E69311 ribonuclease PH (rph) homolog -
           Archaeoglobus fulgidus >gi|2650133|gb|AAB90744.1|
           (AE001070) ribonuclease PH (rph) [Archaeoglobus
           fulgidus]
           Length = 258
           
 Score =  297 bits (752), Expect = 9e-80
 Identities = 147/248 (59%), Positives = 197/248 (79%), Gaps = 8/248 (3%)

Query: 3   EKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPREL 62
           EKPE L ++D  G R+DGRK  ELRPIK+E  VLK A+GS Y+E GKNK+IAAV+GPRE+
Sbjct: 6   EKPEKL-IVD--GLRLDGRKFDELRPIKIEASVLKRADGSCYLEMGKNKVIAAVFGPREV 62

Query: 63  HPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTA 122
           HP+HLQ P +AI+R RYNMAPFSVEERK+PGPDRRSIEISKV K A E  ++ E+FPR+A
Sbjct: 63  HPRHLQDPSKAIIRYRYNMAPFSVEERKRPGPDRRSIEISKVSKEAFEAVIMKELFPRSA 122

Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNY 182
           ID+F+EVLQADAG+R A + AAS+AL DAG+PM+ ++ + A GK +G++VLD  KEEDN+
Sbjct: 123 IDIFVEVLQADAGSRTACLNAASVALVDAGVPMKGMITSVAVGKADGQLVLDPMKEEDNF 182

Query: 183 GEADVPVAIMPLKN----DITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKY 238
           GEAD+P A + ++N     I LLQMDG +T+DE  +A++LA KGA  +Y+ QREA+  +Y
Sbjct: 183 GEADMPFAFL-IRNGKIESIALLQMDGRMTRDEVKQAIELAKKGALQIYEMQREAILRRY 241

Query: 239 LKIAQEVE 246
           +++ +E++
Sbjct: 242 IEVGEEMD 249


>pir||G72623 probable ribonuclease PH APE1447 - Aeropyrum pernix (strain K1)
           >gi|5105131|dbj|BAA80445.1| (AP000061) 246aa long
           hypothetical ribonuclease PH [Aeropyrum pernix]
           Length = 246
           
 Score =  272 bits (688), Expect = 3e-72
 Identities = 133/235 (56%), Positives = 181/235 (76%), Gaps = 1/235 (0%)

Query: 7   GLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKH 66
           G++LI  +GRR DGR   +LRP++M+VG+L NA+GSA +E+G+ +++AAVYGPRE H + 
Sbjct: 8   GVELI-RDGRRHDGRLPEDLRPVRMQVGILHNADGSALVEFGRTRVLAAVYGPREPHQRF 66

Query: 67  LQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVF 126
              PDRA LRVRY+MAPFS +ERK P P RR IE+SKV++ ALEP ++ E FPRT IDVF
Sbjct: 67  YVLPDRAALRVRYHMAPFSTDERKSPAPSRREIELSKVVREALEPVVLAEEFPRTVIDVF 126

Query: 127 IEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEAD 186
           +EVLQAD GTR A +TAASLALADAGIPMR LV   A GKI+G +V+D+++ ED YGEAD
Sbjct: 127 LEVLQADGGTRTAAVTAASLALADAGIPMRALVGGVAVGKIQGVLVVDVDELEDMYGEAD 186

Query: 187 VPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKI 241
           +PVA  P   +ITLLQ++G LT +EF  A+ +A++    V + ++EA+++ YL++
Sbjct: 187 MPVAAAPDIGEITLLQLNGVLTGEEFRTALAMALRAIDRVVEMEKEAIRKSYLEV 241


>pir||T47954 exonuclease RRP41 [imported] - Arabidopsis thaliana
           >gi|6164938|gb|AAF04590.1|AF191741_1 (AF191741)
           exonuclease RRP41 [Arabidopsis thaliana]
           >gi|6850853|emb|CAB71092.1| (AL132959) exonuclease RRP41
           [Arabidopsis thaliana]
           Length = 241
           
 Score =  207 bits (522), Expect = 9e-53
 Identities = 109/230 (47%), Positives = 153/230 (66%), Gaps = 1/230 (0%)

Query: 8   LKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL 67
           ++ ++  G R+DGR+  E+R I  EVGV+  A+GSA  E G  K+IAAVYGPRE+  K  
Sbjct: 1   MEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQ 60

Query: 68  QRP-DRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVF 126
           Q+  D A++   Y+MA FS  +R++   DRRS E+S VI+  +E  ++ E+ P + ID+F
Sbjct: 61  QKKNDHAVVLCEYSMAQFSTGDRRRQKFDRRSTELSLVIRQTMEACILTELMPHSQIDIF 120

Query: 127 IEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEAD 186
           ++VLQAD GTR A I AA+LALADAGIPMRDL  +C+AG +    +LDLN  ED+ G AD
Sbjct: 121 LQVLQADGGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGAD 180

Query: 187 VPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKE 236
           V V I+P  + ++LLQMD  L  + F     LA +G KA+ ++ RE L+E
Sbjct: 181 VTVGILPKLDKVSLLQMDAKLPMETFETVFALASEGCKAIAERIREVLQE 230


>gi|9506689 hypothetical protein [Homo sapiens] >gi|7020801|dbj|BAA91279.1|
           (AK000598) unnamed protein product [Homo sapiens]
           >gi|8927590|gb|AAF82134.1|AF281133_1 (AF281133) exosome
           component Rrp41 [Homo sapiens]
           Length = 245
           
 Score =  183 bits (459), Expect = 2e-45
 Identities = 93/223 (41%), Positives = 142/223 (62%), Gaps = 2/223 (0%)

Query: 7   GLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKH 66
           GL+L+ + G R+DGR+  ELR I+  +GV   A+GSAYIE G  K +A VYGP E+    
Sbjct: 3   GLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSR 62

Query: 67  LQR-PDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEMFPRTAID 124
            +  PDRA++  +Y+ A FS  ERK+ P  DR+S E+   ++   E A++ ++ PR+ ID
Sbjct: 63  ARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQID 122

Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGE 184
           ++++VLQAD GT  A + AA+LA+ DAGIPMRD V AC+AG ++G  + DL+  E+  G 
Sbjct: 123 IYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTALADLSHVEEAAGG 182

Query: 185 ADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVY 227
             + +A++P    I LL+MD  L +D     ++ A + A+ V+
Sbjct: 183 PQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVH 225


>gb|AAF53263.1| (AE003639) CG15481 gene product [Drosophila melanogaster]
           Length = 246
           
 Score =  148 bits (369), Expect = 7e-35
 Identities = 82/232 (35%), Positives = 131/232 (56%), Gaps = 6/232 (2%)

Query: 10  LIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQR 69
           L+ E G R+DGR+ +ELR IK ++GV +  +GSAY+E G  K++AAVYGP +      + 
Sbjct: 7   LLSEQGLRLDGRRPHELRRIKCKLGVFEQPDGSAYMEQGNTKVLAAVYGPHQAKGNQTE- 65

Query: 70  PDRAILRVRYNMAPFSVEERK-KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIE 128
              +++  +Y+ A FS  ERK +P  DR+S+E    ++ AL  A+  E++PR+ ID+++E
Sbjct: 66  ---SVINCQYSQATFSTAERKNRPRGDRKSLEFKLYLQQALSAAIKSELYPRSQIDIYVE 122

Query: 129 VLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVL-DLNKEEDNYGEADV 187
           VLQ D       + AA+LAL DAGI + + + AC A   +  I L D+++ E+  G   +
Sbjct: 123 VLQDDGANYAVALNAATLALIDAGICLNEFIVACTASLSKSNIPLTDISQFEEVSGGPKL 182

Query: 188 PVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYL 239
            VA +P    I  L+M      D     ++ A+ G + +      A+KE  L
Sbjct: 183 TVAALPTAEKIAFLEMSERFHIDHLETVIETAMAGCREIRDILEAAVKEHLL 234


>sp|Q17533|RNPH_CAEEL RIBONUCLEASE PH-LIKE PROTEIN B0564.1 >gi|3873830|emb|CAA97771.3|
           (Z73422) Similarity to H.influenza ribonuclease PH
           (SW:RNPH_HAEIN), contains similarity to Pfam domain:
           PF01138 (3 exoribonuclease family), Score=263.9,
           E-value=7.1e-76, N=1~cDNA EST yk198e11.3 comes from this
           gene~cDNA EST yk247b6.5 comes from this ge>
           Length = 240
           
 Score =  141 bits (351), Expect = 1e-32
 Identities = 83/243 (34%), Positives = 139/243 (57%), Gaps = 5/243 (2%)

Query: 8   LKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL 67
           + +I E+G RIDGR+  ++R I   +G+ +NA GS Y+E G  K++ AVYGP E   K  
Sbjct: 1   MNIISEHGFRIDGRRPAQIRNINTRLGLNRNAEGSCYLEHGNTKVLCAVYGPYE--GKSS 58

Query: 68  QR-PDRAILRVRYNMAPFSVEERK-KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDV 125
           +R  D+  +  +Y+   FS  ERK +   DR+S EIS++++ A E  ++ E FPR+ +D+
Sbjct: 59  KRIEDKCAIVCQYSATKFSGLERKNRTRGDRKSTEISRLLEKAFESVILTEAFPRSQLDI 118

Query: 126 FIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEA 185
           F EV+Q D     A + A SLALADAGIPM+ + +A   G ++G+ ++DL   E+     
Sbjct: 119 FCEVIQGDGSNLAACVNATSLALADAGIPMKGIASAATCGVVDGKPIVDLTSREETDLLP 178

Query: 186 DVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQEV 245
            V +A +  ++++ L+++   L  D  +  V  A K   A   +    + +++LK    +
Sbjct: 179 RVTLATICGRDEVILVELQNRLHIDH-LSTVMDAAKATCADVYECLAVVAQQHLKACAPI 237

Query: 246 EGS 248
            G+
Sbjct: 238 LGN 240


>pir||T11740 hypothetical protein - fission yeast (Schizosaccharomyces pombe)
           >gi|1749490|dbj|BAA13803.1| (D89141) similar to
           Saccharomyces cerevisiae hypothetical 27.6KD protein in
           chromosome VII, SWISS-PROT Accession Number P46948
           [Schizosaccharomyces pombe]
           Length = 242
           
 Score =  126 bits (314), Expect = 2e-28
 Identities = 73/230 (31%), Positives = 126/230 (54%), Gaps = 2/230 (0%)

Query: 8   LKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL 67
           L+++   G R DGR+  E+R  +   G+  + NGSA+IE G  K++  V GP E   K  
Sbjct: 4   LEILSLEGLRNDGRRWDEMRNFQCRFGIEPSENGSAFIELGNTKVLCIVDGPSEPVIKSK 63

Query: 68  QRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKV-IKGALEPALILEMFPRTAIDVF 126
            R DR  + V  N+A FS  + KK     R I++  + ++   E  +  E++PR+ I V+
Sbjct: 64  ARADRTFVNVEINIASFSTIDVKKRFKSDRRIQLQCLALQNTFEEIIQTELYPRSQISVY 123

Query: 127 IEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEAD 186
           + VLQ D     + I A +LAL DAGIP++D V    AG +E +++LDLN  E++   + 
Sbjct: 124 LHVLQDDGAVMASCINATTLALIDAGIPVKDFVCCSTAGIVESDMLLDLNSLEES-ALSW 182

Query: 187 VPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKE 236
           + VA++     +  +Q++  +  D     + +AI G++ +Y   + A+++
Sbjct: 183 LTVAVLGNIKKVVYMQLETSMHLDYLESVMNMAIAGSEHIYNTMQSAVRQ 232


>pir||T11646 tRNA nucleotidyltransferase homolog - fission yeast
           (Schizosaccharomyces pombe) >gi|2706461|emb|CAA15919.1|
           (AL021046) putative ribonuclease PH-like
           [Schizosaccharomyces pombe]
           Length = 242
           
 Score =  126 bits (314), Expect = 2e-28
 Identities = 72/229 (31%), Positives = 126/229 (54%), Gaps = 2/229 (0%)

Query: 9   KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQ 68
           +++   G R DGR+  E+R  +  +G+  + NGSA+IE G  K++  V GP E   K   
Sbjct: 5   EILSLEGLRNDGRRWDEMRNFQCRIGIEPSENGSAFIELGNTKVLCIVDGPSEPVIKSKA 64

Query: 69  RPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKV-IKGALEPALILEMFPRTAIDVFI 127
           R DR  + V  N+A FS  + KK     R I++  + ++   E  +  E++PR+ I V++
Sbjct: 65  RADRTFVNVEINIASFSTIDVKKRFKSDRRIQLQCLALQNTFEEIIQTELYPRSQISVYL 124

Query: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADV 187
            VLQ D     + I A +LAL DAGIP++D V    AG +E +++LDLN  E++   + +
Sbjct: 125 HVLQDDGAVMASCINATTLALIDAGIPVKDFVCCSTAGIVESDMLLDLNSLEES-ALSWL 183

Query: 188 PVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKE 236
            VA++     +  +Q++  +  D     + +AI G++ +Y   + A+++
Sbjct: 184 TVAVLGNIKKVVYMQLETSMHLDYLESVMNMAIAGSEHIYNTMQSAVRQ 232


>gi|6321634 homolog of RNAse PH; Ski6p [Saccharomyces cerevisiae]
           >gi|1176073|sp|P46948|RR41_YEAST RRP41 PROTEIN
           >gi|2132624|pir||S59180 probable membrane protein
           YGR195w - yeast (Saccharomyces cerevisiae)
           >gi|791127|emb|CAA58018.1| (X82775) G7587 [Saccharomyces
           cerevisiae] >gi|1323347|emb|CAA97221.1| (Z72980) ORF
           YGR195w [Saccharomyces cerevisiae]
           Length = 246
           
 Score =  115 bits (285), Expect = 5e-25
 Identities = 78/240 (32%), Positives = 124/240 (51%), Gaps = 8/240 (3%)

Query: 8   LKLIDENGRRIDGRKKYELRPIKMEVGVLKNA-NGSAYIEWGKNKIIAAVYGPRELHPKH 66
           L++    G R+DGR+  ELR  +  +    +A +GS+Y+E G NKII  V GP+E   K 
Sbjct: 4   LEIYSPEGLRLDGRRWNELRRFESSINTHPHAADGSSYMEQGNNKIITLVKGPKEPRLKS 63

Query: 67  LQRPDRAILRVRYNMAPFSVEERKKPGP--DRRSIEISKVIKGALEPALILEMFPRTAID 124
                +A+L V  N+  FS  ER K     +RR +EI   +    E  ++L ++PRT ID
Sbjct: 64  QMDTSKALLNVSVNITKFSKFERSKSSHKNERRVLEIQTSLVRMFEKNVMLNIYPRTVID 123

Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGE 184
           + I VL+ D G   + I   +LAL DAGI M D ++  + G  +   +LD N  E+N   
Sbjct: 124 IEIHVLEQDGGIMGSLINGITLALIDAGISMFDYISGISVGLYDTTPLLDTNSLEEN-AM 182

Query: 185 ADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQE 244
           + V + ++     ++LL ++  +  D     + + I GA  V    R+ + E+  K AQ+
Sbjct: 183 STVTLGVVGKSEKLSLLLVEDKIPLDRLENVLAIGIAGAHRV----RDLMDEELRKHAQK 238


>pir||E70320 polyribonucleotide nucleotidyltransferase - Aquifex aeolicus
           >gi|2982946|gb|AAC06562.1| (AE000679) polyribonucleotide
           nucleotidyltransferase [Aquifex aeolicus]
           Length = 775
           
 Score = 99.8 bits (245), Expect = 3e-20
 Identities = 84/247 (34%), Positives = 125/247 (50%), Gaps = 34/247 (13%)

Query: 13  ENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDR 72
           + G RIDGRK  E+RPI +EV   +  +G+A    G+ +    V          L  PD 
Sbjct: 309 KEGVRIDGRKPNEIRPIWIEVHPFERPHGNAIFTRGQTQAYVTVT---------LGTPDE 359

Query: 73  AIL-------------RVRYNMAPFSVEERKKPGPDRR-SIEISKVIKGALEPALILEMF 118
           A++              + Y+M PFSV E K  GP RR  I    + + A+EP L  E  
Sbjct: 360 ALIIETIAEGEVFKRFMLHYSMPPFSVGEAKPWGPPRRREIGHGALAERAIEPLLPPEEE 419

Query: 119 PRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRD--LVAACAAGKIEGE----IV 172
               I V  ++L+++  T +A +  ASLAL DAG+PM+D   VA  A G I  +    I+
Sbjct: 420 YPFIIRVVSDILESNGSTSMATVCGASLALFDAGVPMKDNKHVAGIAMGLILEKDRYVIL 479

Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229
            D+  +ED+ G+ D  VA    K+ IT +QMD     +TK+  ++A+K A +G   + +K
Sbjct: 480 SDILGDEDHLGDMDFKVA--GTKDGITSVQMDIKVKGITKEIMLDALKQAREGRLYILEK 537

Query: 230 QREALKE 236
             EA+ E
Sbjct: 538 MYEAIPE 544


>sp|O67069|RNPH_AQUAE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE)
           >gi|7435289|pir||B70380 tRNA nucleotidyltransferase (EC
           2.7.7.56) - Aquifex aeolicus >gi|2983451|gb|AAC07032.1|
           (AE000714) RNase PH [Aquifex aeolicus]
           Length = 255
           
 Score = 99.5 bits (244), Expect = 3e-20
 Identities = 75/234 (32%), Positives = 120/234 (51%), Gaps = 19/234 (8%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R DGRK+ +LRP+ ++   L+   GS  I +GK K+I       E  P  L+   +  + 
Sbjct: 2   RSDGRKEDQLRPVSIQRDFLEYPEGSCLISFGKTKVICTA-SVIENVPNWLKGKGQGWIT 60

Query: 77  VRYNMAPFSVEER--KKPGPDR---RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y+M P + ++R  ++    R   R+ EI ++I  A+  A+ L       I V  +V+Q
Sbjct: 61  AEYSMLPRATQQRTIRESVQGRIGGRTHEIQRMIGRAMRTAVELTKIGERTIWVDCDVIQ 120

Query: 132 ADAGTRVAGITAASLALADAGI-----------PMRDLVAACAAGKIEGEIVLDLNKEED 180
           AD GTR A IT A +A+ADA I           P++D VAA + G +   I+LDLN EED
Sbjct: 121 ADGGTRTAAITGAFVAVADAIIKLHKEGIIEETPIKDFVAAVSVGIVNDRILLDLNFEED 180

Query: 181 NYGEADVPV--AIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQRE 232
           +  + D+ V        +++  +  +   TKDE I+ + LA KG   + + Q++
Sbjct: 181 SAAQVDMNVVGTGSGRLSEVHTMGEEYSFTKDELIKMLDLAQKGINELIELQKK 234


>pir||D82978 ribonuclease PH PA5334 [imported] - Pseudomonas aeruginosa  (strain
           PAO1) >gi|9951653|gb|AAG08719.1|AE004946_3 (AE004946)
           ribonuclease PH [Pseudomonas aeruginosa]
           Length = 239
           
 Score = 99.1 bits (243), Expect = 4e-20
 Identities = 76/241 (31%), Positives = 118/241 (48%), Gaps = 25/241 (10%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R  GR   +LRPI++     K+A GS  +E+G  K+I  V     + P+ L+   +  L 
Sbjct: 3   RPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGV-PRFLKGQGQGWLT 61

Query: 77  VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y M P S  ER +    R     R++EI ++I  +L  AL L       + +  +V+Q
Sbjct: 62  AEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLRAALDLSKLGENTLYIDCDVIQ 121

Query: 132 ADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEED 180
           AD GTR A IT A++AL DA           G P++ +VAA + G  +G  VLDL+  ED
Sbjct: 122 ADGGTRTASITGATVALIDALAVLKKRGALKGNPLKQMVAAVSVGIYQGVPVLDLDYLED 181

Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEA-----VKLAIKGAKAVYQKQREALK 235
           +  E D+ V +         +++ G      F  A     ++LA +G + +++ QR AL 
Sbjct: 182 SAAETDLNVVMTDAGG---FIEVQGTAEGAPFRPAELNAMLELAQQGMQELFELQRAALA 238

Query: 236 E 236
           E
Sbjct: 239 E 239


>sp|P03842|RNPH_ECOLI RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE)
           Length = 238
           
 Score = 94.0 bits (230), Expect = 1e-18
 Identities = 71/236 (30%), Positives = 111/236 (46%), Gaps = 25/236 (10%)

Query: 20  GRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRY 79
           GR   ++RP+ +     K+A GS  +E+G  K++       E  P+ L+   +  +   Y
Sbjct: 5   GRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTA-SIEEGVPRFLKGQGQGWITAEY 63

Query: 80  NMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADA 134
            M P S   R      K     R++EI ++I  AL  A+ L+      I +  +VLQAD 
Sbjct: 64  GMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADG 123

Query: 135 GTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEEDNYG 183
           GTR A IT A +AL DA             PM+ +VAA + G + GE V DL   ED+  
Sbjct: 124 GTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAA 183

Query: 184 EADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQKQREAL 234
           E D+ V    +  D  ++++ G       T +E +  + LA  G +++   Q+ AL
Sbjct: 184 ETDMNVV---MTEDGRIIEVQGTAEGEPFTHEELLILLALARGGIESIVATQKAAL 236


>sp|P50597|RNPH_PSEAE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE)
           >gi|1079663|gb|AAC44429.1| (U38241) RNase PH
           [Pseudomonas aeruginosa]
           Length = 239
           
 Score = 93.6 bits (229), Expect = 2e-18
 Identities = 73/241 (30%), Positives = 117/241 (48%), Gaps = 25/241 (10%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R  GR   +LRPI++     K+A GS  +E+G  K+I  V     + P+ L+   +  L 
Sbjct: 3   RPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGV-PRFLKGQGQGWLT 61

Query: 77  VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y M   S  ER +    R     R++EI ++I  +L  AL L       + +  +V+Q
Sbjct: 62  AEYGMLRRSTGERNQREASRGKQGGRTLEIQRLIDRSLRAALDLSKLGENTLYIDCDVIQ 121

Query: 132 ADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEED 180
            D GTR A IT A+++L DA           G P++ +VAA + G  +G  VLDL+  ED
Sbjct: 122 TDGGTRTASITGATVSLIDALAVLKKRVALKGNPLKQIVAAVSVGIYQGVPVLDLDYLED 181

Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEA-----VKLAIKGAKAVYQKQREALK 235
           +  E+D+ V +   +     +++ G      F  A     ++LA +G + + + QR AL 
Sbjct: 182 SAAESDLNVVMTDCRR---FIEVQGTAEGAPFRPAELNAMLELAQQGMQELVRTQRAALA 238

Query: 236 E 236
           E
Sbjct: 239 E 239


>sp|P44444|RNPH_HAEIN RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE)
           >gi|1075223|pir||A64059 tRNA nucleotidyltransferase (EC
           2.7.7.56) - Haemophilus influenzae (strain Rd KW20)
           >gi|1573239|gb|AAC21939.1| (U32713) ribonuclease PH
           (rph) [Haemophilus influenzae Rd]
           Length = 238
           
 Score = 93.2 bits (228), Expect = 3e-18
 Identities = 70/239 (29%), Positives = 118/239 (49%), Gaps = 25/239 (10%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R + R+  + R IK+     K+A GS  +E+G  K++       +  P+ L+   +  + 
Sbjct: 2   RPNNRENNQPRQIKITRNYTKHAEGSVLVEFGDTKVLCTAT-VEDAVPRFLKGQGQGWVT 60

Query: 77  VRYNMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y M P S   R      K     R++EI ++I  +L   + L+     AI +  +V+Q
Sbjct: 61  AEYGMLPRSTHSRMQREAAKGKQGGRTMEIQRLIARSLRAMVDLKALGERAITLDCDVIQ 120

Query: 132 ADAGTRVAGITAASLALADA--GI---------PMRDLVAACAAGKIEGEIVLDLNKEED 180
           AD GTR A IT A++AL DA  G+         P++ LV+A + G ++G+ V DL   ED
Sbjct: 121 ADGGTRTASITGAAVALCDAINGLIENGTLKTNPIKGLVSAISVGIVDGQAVCDLEYVED 180

Query: 181 NYGEADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQKQREAL 234
           +  E D+ V +M    D  ++++ G       + +E +  + LA +G   ++  QREAL
Sbjct: 181 SAAETDMNVVMM---EDGRMIEVQGTAEGEPFSHEELLTLLDLAKQGCNQIFIAQREAL 236


>pir||QQECPE tRNA nucleotidyltransferase (EC 2.7.7.56) - Escherichia coli
           >gi|499181|emb|CAA25357.1| (X00781) unidentified reading
           frame (orfE) [Escherichia coli]
           Length = 238
           
 Score = 92.4 bits (226), Expect = 4e-18
 Identities = 71/236 (30%), Positives = 111/236 (46%), Gaps = 25/236 (10%)

Query: 20  GRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRY 79
           GR   ++RP+ +     K+A GS  +E+G  K++       E  P+ L+   +  +   Y
Sbjct: 5   GRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTA-SIEEGVPRFLKGQGQGWITAEY 63

Query: 80  NMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADA 134
            M P S   R      K     R++EI ++I  AL  A+ L+      I +  +VLQADA
Sbjct: 64  GMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADA 123

Query: 135 GTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEEDNYG 183
            TR A IT A +AL DA             PM+ +VAA + G + GE V DL   ED+  
Sbjct: 124 WTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAA 183

Query: 184 EADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQKQREAL 234
           E D+ V    +  D  ++++ G       T +E +  + LA  G +++   Q+ AL
Sbjct: 184 ETDMNVV---MTEDGRIIEVQGTAEGEPFTHEELLILLALARGGIESIVATQKAAL 236


>pir||A72264 polynucleotide phosphorylase - Thermotoga maritima (strain MSB8)
           >gi|4981905|gb|AAD36416.1|AE001789_1 (AE001789)
           polynucleotide phosphorylase [Thermotoga maritima]
           Length = 708
           
 Score = 91.7 bits (224), Expect = 8e-18
 Identities = 76/208 (36%), Positives = 107/208 (50%), Gaps = 18/208 (8%)

Query: 9   KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQ 68
           +LI E G R DGRK  E+RPI  EVG+    +GSA    G+ + +  V       P  +Q
Sbjct: 309 RLIVEKGIRADGRKPTEIRPISCEVGLFPRTHGSALFTRGETQSLGIVTLGA---PMDVQ 365

Query: 69  RPDRAI------LRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEM-FPR 120
             D  +        + YN  PF   E K   GP RR I    + + AL+  L  E  FP 
Sbjct: 366 IIDTLLEEGVKRFMLHYNFPPFCTGEVKPLRGPSRREIGHGHLAERALKNMLPPEEEFPY 425

Query: 121 TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI---EGEIVL-DLN 176
           T I V  E+L+++  + +A + + SLAL DAG+P++  VA  A G I   + EI+L D+ 
Sbjct: 426 T-IRVVSEILESNGSSSMATVCSGSLALMDAGVPIKKHVAGIAMGLILEEDAEIILTDII 484

Query: 177 KEEDNYGEADVPVAIMPLKNDITLLQMD 204
             ED+YG+ D  VA    ++ IT  QMD
Sbjct: 485 GMEDHYGDMDFKVA--GTRDGITAFQMD 510


>emb|CAB06341.1| (Z84207) polynucleotide phosphorylase [Thermus thermophilus]
           Length = 713
           
 Score = 91.3 bits (223), Expect = 1e-17
 Identities = 78/220 (35%), Positives = 112/220 (50%), Gaps = 15/220 (6%)

Query: 9   KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPK 65
           +L+ E G+R DGR   +LRPI +EV VL  A+GSA    G+ +++  V    G  E    
Sbjct: 319 RLVLEEGKRADGRGPKDLRPIWIEVDVLPRAHGSAVFTRGETQVLGTVTLGTGRDEQILD 378

Query: 66  HLQRPDRAILRVRYNMAPFSV-EERKKPGPDRRSIEISKVIKGALEPALILEM-FPRTAI 123
            L   +     V YN  PFS  E R+  G  RR +    + K AL+  +  E  FP T I
Sbjct: 379 DLGIDETEKFLVHYNFPPFSTGEVRRLRGVSRREVGHGNLAKRALKAVMPKEEDFPYT-I 437

Query: 124 DVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEE 179
            V  +VL+++  + +A + A  LAL DAG+P+R  VA  A G +  E    I+ D+   E
Sbjct: 438 RVVGDVLESNGSSSMATVCAGCLALMDAGVPIRAPVAGVAMGLVWEENRAVILTDILGLE 497

Query: 180 DNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAV 216
           D  G+ D  VA    +  +T LQMD   G L ++   EA+
Sbjct: 498 DALGDMDFKVA--GTRKGVTALQMDNKVGGLPREVLKEAL 535


>gb|AAF72714.1|AF263927_2 (AF263927) ribonuclease PH [Carnobacterium sp. St2]
           Length = 364
           
 Score = 90.9 bits (222), Expect = 1e-17
 Identities = 77/247 (31%), Positives = 121/247 (48%), Gaps = 24/247 (9%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRELHPKHLQRPDRAIL 75
           R + RK  ELR + +E   LK+  GS  + +G  K+I  A   P+   P  ++   +  +
Sbjct: 2   RTNTRKNDELRLVTIETNYLKHPEGSVLVSFGDTKVICNATVEPKV--PPFMRGQGKGWV 59

Query: 76  RVRYNMAPFS-----VEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVL 130
              Y M P +     + E  K     R++EI ++I  +L   + LE     AI V  +V+
Sbjct: 60  HAEYAMLPRATNTRTIREAAKGKLTGRTMEIQRLIARSLRSVIDLEKLGERAITVDCDVI 119

Query: 131 QADAGTRVAGITAASLA-------LADAG----IPMRDLVAACAAG-KIEGEIVLDLNKE 178
           QAD GTR A IT A +A       L D+G     P+++ +AA + G   +GE VLDL+  
Sbjct: 120 QADGGTRTASITGAFVALKMAIQTLLDSGQLTEDPVKENIAAVSVGITKQGEAVLDLDYL 179

Query: 179 EDNYGEADVPVAIMPLKNDITLLQMDG---YLTKDEFIEAVKLAIKGAKAVYQKQREALK 235
           ED+    D+ +  M    +   LQ  G     + D+ +E ++L  KG   ++Q Q +ALK
Sbjct: 180 EDSSAAVDMNL-FMTANGEFFELQGTGEEATFSNDQLMEMLELGKKGLNELFQIQTQALK 238

Query: 236 EKYLKIA 242
           E  +K A
Sbjct: 239 ESKVKKA 245


>gb|AAA61996.1| (L10328) RNase PH [Escherichia coli] >gi|1790074|gb|AAC76667.1|
           (AE000441) RNase PH [Escherichia coli K12]
           Length = 228
           
 Score = 88.5 bits (216), Expect = 7e-17
 Identities = 64/209 (30%), Positives = 98/209 (46%), Gaps = 20/209 (9%)

Query: 20  GRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRY 79
           GR   ++RP+ +     K+A GS  +E+G  K++       E  P+ L+   +  +   Y
Sbjct: 5   GRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTA-SIEEGVPRFLKGQGQGWITAEY 63

Query: 80  NMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADA 134
            M P S   R      K     R++EI ++I  AL  A+ L+      I +  +VLQAD 
Sbjct: 64  GMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADG 123

Query: 135 GTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEEDNYG 183
           GTR A IT A +AL DA             PM+ +VAA + G + GE V DL   ED+  
Sbjct: 124 GTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAA 183

Query: 184 EADVPVAIMPLKNDITLLQMDGYLTKDEF 212
           E D+ V    +  D  ++++ G    + F
Sbjct: 184 ETDMNVV---MTEDGRIIEVQGTAEGEPF 209


>sp|P28619|RNPH_BACSU RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE)
           >gi|143444|gb|AAA22705.1| (M85163) RNase PH [Bacillus
           subtilis] >gi|1770059|emb|CAA99554.1| (Z75208) RNase PH
           [Bacillus subtilis] >gi|2635302|emb|CAB14797.1| (Z99118)
           ribonuclease PH [Bacillus subtilis]
           Length = 245
           
 Score = 87.8 bits (214), Expect = 1e-16
 Identities = 77/238 (32%), Positives = 113/238 (47%), Gaps = 22/238 (9%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R DGR+  ELRPI  ++  + +  GS  I  G  K+I       +  P  L+   +  + 
Sbjct: 2   RHDGRQHDELRPITFDLDFISHPEGSVLITAGNTKVICNA-SVEDRVPPFLRGGGKGWIT 60

Query: 77  VRYNMAPFSVEER-----KKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y+M P +  +R      K     R++EI ++I  AL   + LE      I +  +V+Q
Sbjct: 61  AEYSMLPRATNQRTIRESSKGKISGRTMEIQRLIGRALRAVVDLEKLGERTIWIDCDVIQ 120

Query: 132 ADAGTRVAGITAASLALA-------DAGI----PMRDLVAACAAG-KIEGEIVLDLNKEE 179
           AD GTR A IT A LA+A        AG     P+ D +AA + G   E  I+LDLN EE
Sbjct: 121 ADGGTRTASITGAFLAMAIAIGKLIKAGTIKTNPITDFLAAISVGIDKEQGILLDLNYEE 180

Query: 180 DNYGEADVPVAIMPLKNDITLLQMDG---YLTKDEFIEAVKLAIKGAKAVYQKQREAL 234
           D+  E D+ V IM        LQ  G     ++++    + LA KG + +  KQ+E L
Sbjct: 181 DSSAEVDMNV-IMTGSGRFVELQGTGEEATFSREDLNGLLGLAEKGIQELIDKQKEVL 237


>sp|Q10628|RNPH_MYCTU PROBABLE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE)
           >gi|7435288|pir||C70739 probable rphA protein -
           Mycobacterium tuberculosis (strain H37RV)
           >gi|1419043|emb|CAA99973.1| (Z75555) rphA [Mycobacterium
           tuberculosis]
           Length = 259
           
 Score = 87.8 bits (214), Expect = 1e-16
 Identities = 72/245 (29%), Positives = 111/245 (44%), Gaps = 26/245 (10%)

Query: 16  RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAIL 75
           +R DGR  +ELRP+ +  G  +N  GS  IE+G  K++       E  P+  +      L
Sbjct: 3   KREDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTA-SVTEGVPRWRKATGLGWL 61

Query: 76  RVRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVL 130
              Y M P +   R      R     R+ EIS++I  +L   + L       I +  +VL
Sbjct: 62  TAEYAMLPSATHSRSDRESVRGRLSGRTQEISRLIGRSLRACIDLAALGENTIAIDCDVL 121

Query: 131 QADAGTRVAGITAASLALADAGI------------PMRDLVAACAAGKIEGEIVLDLNKE 178
           QAD GTR A IT A +ALADA              P+   +AA + G ++G I +DL  E
Sbjct: 122 QADGGTRTAAITGAYVALADAVTYLSAAGKLSDPRPLSCAIAAVSVGVVDGRIRVDLPYE 181

Query: 179 EDNYGEADVPVAIMPLKNDITLLQMDG-----YLTKDEFIEAVKLAIKGAKAVYQKQREA 233
           ED+  E D+ V      +  TL+++ G        +    + + +A+     ++  QR+A
Sbjct: 182 EDSRAEVDMNVV---ATDTGTLVEIQGTGEGATFARSTLDKLLDMALGACDTLFAAQRDA 238

Query: 234 LKEKY 238
           L   Y
Sbjct: 239 LALPY 243


>sp|O87792|PNP_PSEPU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE
           PHOSPHORYLASE) (PNPASE) >gi|3650364|emb|CAA77048.1|
           (Y18132) polyribonucleotide nucleotidyltransferase
           [Pseudomonas putida]
           Length = 701
           
 Score = 87.4 bits (213), Expect = 1e-16
 Identities = 68/201 (33%), Positives = 109/201 (53%), Gaps = 13/201 (6%)

Query: 14  NGR-RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK--IIAAVYGPRELHPKH-LQR 69
           NG+ RIDGR    +RP+ +EVGVL   +GSA    G+ +  ++A +   R+      L+ 
Sbjct: 312 NGKPRIDGRDNKTVRPLNIEVGVLPKTHGSALFTRGETQALVVATLGTARDAQLLDTLEG 371

Query: 70  PDRAILRVRYNMAPFSVEE-RKKPGPDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFI 127
             +    + YN  PFSV E  +  G  RR I   ++ + +++  L   ++FP T I V  
Sbjct: 372 EKKDPFMLHYNFPPFSVGECGRMGGAGRREIGHGRLARRSVQAMLPAADVFPYT-IRVVS 430

Query: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYG 183
           E+ +++  + +A +  ASLAL DAG+PM+  VA  A G + EG+   ++ D+  +ED+ G
Sbjct: 431 EITESNGSSSMASVCGASLALMDAGVPMKAPVAGIAMGLVKEGDKFAVLTDILGDEDHLG 490

Query: 184 EADVPVAIMPLKNDITLLQMD 204
           + D  VA       +T LQMD
Sbjct: 491 DMDFKVA--GTAKGVTALQMD 509


>pir||C83052 polyribonucleotide nucleotidyltransferase PA4740 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9951002|gb|AAG08126.1|AE004888_1 (AE004888)
           polyribonucleotide nucleotidyltransferase [Pseudomonas
           aeruginosa]
           Length = 701
           
 Score = 87.4 bits (213), Expect = 1e-16
 Identities = 72/203 (35%), Positives = 110/203 (53%), Gaps = 17/203 (8%)

Query: 14  NGR-RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK--IIAAVYGPRE---LHPKHL 67
           NG+ RIDGR    +RP+++EVGVL   +GSA    G+ +  ++A +   R+   L     
Sbjct: 312 NGKPRIDGRDTRTVRPLRIEVGVLGKTHGSALFTRGETQALVVATLGTARDAQLLDTLEG 371

Query: 68  QRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDV 125
           +R D  +L   YN  PFSV E  + G P RR I   ++ +  +   L   + FP T I V
Sbjct: 372 ERKDAFMLH--YNFPPFSVGECGRMGSPGRREIGHGRLARRGVAAMLPTQDEFPYT-IRV 428

Query: 126 FIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDN 181
             E+ +++  + +A +  ASLAL DAG+P++  VA  A G + EGE   ++ D+  +ED+
Sbjct: 429 VSEITESNGSSSMASVCGASLALMDAGVPVKAPVAGIAMGLVKEGEKFAVLTDILGDEDH 488

Query: 182 YGEADVPVAIMPLKNDITLLQMD 204
            G+ D  VA       +T LQMD
Sbjct: 489 LGDMDFKVA--GTDKGVTALQMD 509


>dbj|BAB06787.1| (AP001517) ribonuclease PH [Bacillus halodurans]
           Length = 257
           
 Score = 87.0 bits (212), Expect = 2e-16
 Identities = 74/239 (30%), Positives = 116/239 (47%), Gaps = 24/239 (10%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R+D RK  ELRPI +E+  L +  GS  I  G  K+I       +  P  L+   +  + 
Sbjct: 2   RMDERKADELRPISIEINYLHHPEGSVLISIGNTKVICTA-SLEDRVPPFLRGQGKGWIT 60

Query: 77  VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y+M P + E+R      R     R++EI ++I  AL   + L+      + +  +V+Q
Sbjct: 61  AEYSMLPRATEQRNMRESTRGKVSGRTMEIQRLIGRALRSIIDLDKIGERTVWIDCDVIQ 120

Query: 132 ADAGTRVAGITAASL--------ALADAGI---PMRDLVAACAAGKIEGEI--VLDLNKE 178
           AD GTR   IT A +        ALA+  I   P+ D +AA + G I+ ++  +LDL   
Sbjct: 121 ADGGTRTTSITGAFVALSLAMEKALANGAIQEWPIDDFLAAVSVG-IDPKLGAILDLCYA 179

Query: 179 EDNYGEADVPVAIMPLKNDITLLQMDG---YLTKDEFIEAVKLAIKGAKAVYQKQREAL 234
           ED   E D+ V +M  K +   LQ  G     + ++ +  + LA KG K + ++QR AL
Sbjct: 180 EDAQAEVDMNV-VMTGKGEYVELQGTGEEATFSHNQLLTILALADKGIKQLIEEQRNAL 237


>pir||A44914 tRNA nucleotidyltransferase (EC 2.7.7.56) - Bacillus subtilis
           Length = 245
           
 Score = 86.6 bits (211), Expect = 3e-16
 Identities = 77/238 (32%), Positives = 112/238 (46%), Gaps = 22/238 (9%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R DGR   ELRPI  ++  + +  GS  I  G  K+I       +  P  L+   +  + 
Sbjct: 2   RHDGRGHDELRPITFDLDFISHPEGSVLITAGNTKVICNA-SVEDRVPPFLRGGGKGWIT 60

Query: 77  VRYNMAPFS-----VEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y+M P +     + E  K     R++EI ++I  AL   + LE      I +  +V+Q
Sbjct: 61  AEYSMLPRATNGRTIRESSKGKISGRTMEIQRLIGRALRAVVDLEKLGERTIWIDCDVIQ 120

Query: 132 ADAGTRVAGITAASLALA-------DAGI----PMRDLVAACAAG-KIEGEIVLDLNKEE 179
           AD GTR A IT A LA+A        AG     P+ D +AA + G   E  I+LDLN EE
Sbjct: 121 ADGGTRTASITGAFLAMAIAIGKLIKAGTIKTNPITDFLAAISVGIDKEQGILLDLNYEE 180

Query: 180 DNYGEADVPVAIMPLKNDITLLQMDG---YLTKDEFIEAVKLAIKGAKAVYQKQREAL 234
           D+  E D+ V IM        LQ  G     ++++    + LA KG + +  KQ+E L
Sbjct: 181 DSSAEVDMNV-IMTGSGRFVELQGTGEEATFSREDLNGLLGLAEKGIQELIDKQKEVL 237


>pir||G81332 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) Cj1253
           [imported] - Campylobacter jejuni (strain NCTC 11168)
           >gi|6968686|emb|CAB73507.1| (AL139077)
           polyribonucleotide nucleotidyltransferase [Campylobacter
           jejuni]
           Length = 719
           
 Score = 85.8 bits (209), Expect = 4e-16
 Identities = 78/245 (31%), Positives = 119/245 (47%), Gaps = 21/245 (8%)

Query: 9   KLIDEN----GRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK--IIAAVYGPREL 62
           KLI E     G+R DGR   E+RPI +E  +L NA+GS     G+ +  ++A + G  + 
Sbjct: 324 KLIREQILNEGKRADGRSLNEVRPISIETNILPNAHGSCLFTRGQTQALVVATLGGENDS 383

Query: 63  HPKHL---QRPDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEMF 118
               L   + P      V YN   FSV E      P RR +    + K AL P+ + E +
Sbjct: 384 QMIDLLTEKNPISERFMVNYNFPGFSVGEASPIKAPGRRELGHGNLAKRALYPS-VDENY 442

Query: 119 PRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI----EGEIVLD 174
           P   I +  E+L+++  + +A +   SLAL  AG+P   LVA  A G I    +  ++ D
Sbjct: 443 P-YVIRLVSEILESNGSSSMATVCGGSLALKAAGVPSLKLVAGVAMGLIFEDNKYAVLTD 501

Query: 175 LNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQKQR 231
           +   ED+ G+ D  VA    K+ +T LQMD   G + ++   +A+  A +G   +     
Sbjct: 502 IMGLEDHDGDMDFKVA--GSKDGVTALQMDIKLGGIDQEILKQALYQAKEGRIHILNIME 559

Query: 232 EALKE 236
           EA KE
Sbjct: 560 EAAKE 564


>sp|P37939|RNPH_MYCLE PROBABLE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE)
           >gi|2145985|pir||S72788 tRNA nucleotidyltransferase (EC
           2.7.7.56) - Mycobacterium leprae
           >gi|466905|gb|AAA50880.1| (U00014) rnpH; ribonuclease
           PH; B1549_C1_182 [Mycobacterium leprae]
           Length = 259
           
 Score = 85.4 bits (208), Expect = 6e-16
 Identities = 72/250 (28%), Positives = 114/250 (44%), Gaps = 26/250 (10%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R DGR   ELR + +  G  ++  GS  IE+G  K++     P E  P+  +   +  L 
Sbjct: 4   RADGRLDDELRAVVITRGFTEHPAGSVLIEFGHTKVMCTA-SPTEGVPRWRKGSGKGWLT 62

Query: 77  VRYNMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y M P +   R      K     R+ EIS++I  +L   + L       I V  +VLQ
Sbjct: 63  AEYAMLPSATHTRSERESVKGRLSGRTQEISRLIGRSLRACIDLAALGENTIAVDCDVLQ 122

Query: 132 ADAGTRVAGITAASLALADAGI------------PMRDLVAACAAGKIEGEIVLDLNKEE 179
           AD GTR A +T A +ALADA              P+   +AA + G ++G I +DL+ EE
Sbjct: 123 ADGGTRTAAVTGAYVALADAVTYLSAAGRLLDPRPLSCAIAAVSVGVVDGRIRVDLSYEE 182

Query: 180 DNYGEADVPVAIMPLKNDITLLQMDG-----YLTKDEFIEAVKLAIKGAKAVYQKQREAL 234
           D+  E D+ V      +  TL+++ G        +    + + +A+     ++  QR+AL
Sbjct: 183 DSRAEVDMNVI---ATDTGTLVEIQGTGEGATFPRSTLDKLLDMALGACDKLFVAQRDAL 239

Query: 235 KEKYLKIAQE 244
              Y  ++ E
Sbjct: 240 ALPYQGMSPE 249


>sp|P50849|PNPA_BACSU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE
           PHOSPHORYLASE) (PNPASE) (VEGETATIVE PROTEIN 15) (VEG15)
           >gi|2127172|pir||S70691 polyribonucleotide
           nucleotidyltransferase (EC 2.7.7.8) alpha chain pnpA -
           Bacillus subtilis >gi|1184680|gb|AAC43595.1| (U29668)
           polynucleotide phosphorylase [Bacillus subtilis]
           >gi|2634041|emb|CAB13542.1| (Z99112) polynucleotide
           phosphorylase (PNPase) [Bacillus subtilis]
           >gi|1589234|prf||2210369A polynucleotide phosphorylase
           [Bacillus subtilis]
           Length = 705
           
 Score = 84.7 bits (206), Expect = 1e-15
 Identities = 79/254 (31%), Positives = 126/254 (49%), Gaps = 19/254 (7%)

Query: 4   KPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-----AVYG 58
           K E  +LI E   R DGR   ++RP+  EVG+L   +GS     G+ + ++     A+  
Sbjct: 303 KNEVRRLITEEKVRPDGRGVDQIRPLSSEVGLLPRTHGSGLFTRGQTQALSVCTLGALGD 362

Query: 59  PRELHPKHLQRPDRAILRVRYNMAPFSVEER-KKPGPDRRSIEISKVIKGALEPALILEM 117
            + L    ++   R +    YN   FSV E     GP RR I    + + ALEP +  E 
Sbjct: 363 VQILDGLGVEESKRFMHH--YNFPQFSVGETGPMRGPGRREIGHGALGERALEPVIPSEK 420

Query: 118 -FPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIE-GE---IV 172
            FP T + +  EVL+++  T  A I A++LA+ DAG+P++  VA  A G ++ GE   ++
Sbjct: 421 DFPYT-VRLVSEVLESNGSTSQASICASTLAMMDAGVPIKAPVAGIAMGLVKSGEHYTVL 479

Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229
            D+   ED  G+ D  VA    +  +T LQMD     L+++   EA++ A KG   +   
Sbjct: 480 TDIQGMEDALGDMDFKVA--GTEKGVTALQMDIKIEGLSREILEEALQQAKKGRMEILNS 537

Query: 230 QREALKEKYLKIAQ 243
               L E   ++++
Sbjct: 538 MLATLSESRKELSR 551


>sp|P57454|PNP_BUCAI POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE
           PHOSPHORYLASE) (PNPASE) >gi|10039043|dbj|BAB13077.1|
           (AP001119) polyribonucleotide nucleotidyltransferase
           [Buchnera sp. APS]
           Length = 707
           
 Score = 84.7 bits (206), Expect = 1e-15
 Identities = 71/214 (33%), Positives = 109/214 (50%), Gaps = 16/214 (7%)

Query: 2   MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRE 61
           +EK    K I  N  RIDGR+K  +R + +  G+L   +GSA    G+ + + +V     
Sbjct: 300 IEKKVVRKRILSNQTRIDGREKDMIRALDVRTGILPRTHGSALFTRGETQSLVSVTLGTS 359

Query: 62  LHPKHLQ-----RPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-I 114
              ++L      R D  +    YN  P+SV E    G P RR I   ++ K +L   +  
Sbjct: 360 RDAQNLDELLGDRIDNFLFH--YNFPPYSVGEIGMVGSPKRREIGHGRLAKRSLLAVMPT 417

Query: 115 LEMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE--- 170
           LE FP T I V  E+ +++  + +A +  ASLAL DAG+P++  VA  + G + EG    
Sbjct: 418 LENFPYT-IRVVSEITESNGSSSMASVCGASLALMDAGVPIKSAVAGISMGLVKEGNQHV 476

Query: 171 IVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMD 204
           ++ D+  +ED+ G+ D  VA    +  IT LQMD
Sbjct: 477 LLSDILGDEDHLGDMDFKVA--GTEEGITALQMD 508


>dbj|BAB06126.1| (AP001515) polynucleotide phosphorylase [Bacillus halodurans]
           Length = 704
           
 Score = 84.3 bits (205), Expect = 1e-15
 Identities = 76/247 (30%), Positives = 121/247 (48%), Gaps = 19/247 (7%)

Query: 4   KPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-----AVYG 58
           K E  +LI     R DGR+  E+RP+  +VG+L   +GS     G+ + ++     A+  
Sbjct: 301 KEEVRRLITVEKIRPDGREIDEIRPLSSQVGILPRTHGSGLFTRGQTQALSICTLGALGD 360

Query: 59  PRELHPKHLQRPDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEM 117
            + L    ++   R +    YN   FSV E     GP RR I    + + ALEP +  E 
Sbjct: 361 VQILDGLGIEESKRFMHH--YNFPQFSVGETGPIRGPGRREIGHGALGERALEPVIPSEQ 418

Query: 118 -FPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IV 172
            FP T I +  EVL+++  T  A I A++LA+ DAG+P++  VA  A G ++ +    ++
Sbjct: 419 DFPYT-IRLVSEVLESNGSTSQASICASTLAMMDAGVPIKAPVAGIAMGLVKQDEHVSVL 477

Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229
            D+   ED  G+ D  VA    +  +T LQMD     + +    +A++ A KG   +   
Sbjct: 478 TDIQGMEDALGDMDFKVA--GTRKGVTALQMDIKISGIDRAILEQALEQARKGRMIILDN 535

Query: 230 QREALKE 236
             EA+ E
Sbjct: 536 MLEAISE 542


>pir||S74509 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain
           - Synechocystis sp. (strain PCC 6803)
           >gi|1651733|dbj|BAA16661.1| (D90899) polyribonucleotide
           nucleotidyltransferase [Synechocystis sp.]
           Length = 718
           
 Score = 82.7 bits (201), Expect = 4e-15
 Identities = 78/247 (31%), Positives = 120/247 (48%), Gaps = 27/247 (10%)

Query: 9   KLIDENGRRIDGRKKYELRPIKMEVGVL-KNANGSAYIEWGKNKIIA-AVYGPR------ 60
           K I ++G R+DGRK  ++RPI  EVG L +  +GS     G  ++++ A  G        
Sbjct: 316 KQIVDDGVRVDGRKLEQVRPISCEVGFLPRRVHGSGLFNRGLTQVLSLATLGSPGDAQDL 375

Query: 61  --ELHPKHLQRPDRAILRVRYNMAPFSV-EERKKPGPDRRSIEISKVIKGALEPALI-LE 116
             +LHP+  +R         YN  P+SV E R    P RR I    + + A+ P L   E
Sbjct: 376 ADDLHPEDEKR-----YLHHYNFPPYSVGEARPMRSPGRREIGHGALAERAIIPVLPPQE 430

Query: 117 MFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IV 172
            FP   + V  EVL ++  T +  +  ++LAL DAG+P++  V+  A G I EG+   I+
Sbjct: 431 DFPYV-VRVVSEVLSSNGSTSMGSVCGSTLALMDAGVPIKKPVSGAAMGLIKEGDEIRIL 489

Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229
            D+   ED  G+ D  VA     + IT LQMD     L+ +   +A+  A+     +  K
Sbjct: 490 TDIQGIEDFLGDMDFKVA--GTDSGITALQMDMKIDGLSMEVVSKAIMQALPARLHILDK 547

Query: 230 QREALKE 236
               ++E
Sbjct: 548 MLATIRE 554


>pir||T36127 probable ribonuclease PH - Streptomyces coelicolor
           >gi|5531353|emb|CAB50985.1| (AL096852) putative
           ribonuclease PH [Streptomyces coelicolor A3(2)]
           Length = 245
           
 Score = 82.7 bits (201), Expect = 4e-15
 Identities = 71/245 (28%), Positives = 109/245 (43%), Gaps = 35/245 (14%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           RIDGR   +LRP+ +E G  K+A GS  + +G  K++       E  P+  +      + 
Sbjct: 3   RIDGRTPQQLRPVTIERGWSKHAEGSVLVSFGDTKVLCNA-SVTEGVPRWRKGSGEGWVT 61

Query: 77  VRYNMAPFSVEERKKPGPDRRSI---------EISKVIKGALEPALILEMFPRTAIDVFI 127
             Y M P +   R     DR S+         EIS++I  +L   +  +      + +  
Sbjct: 62  AEYAMLPRATNTRG----DRESVKGRIGGRTHEISRLIGRSLRAVIDYKALGENTVVLDC 117

Query: 128 EVLQADAGTRVAGITAASLALADAGI-------------PMRDLVAACAAGKIEGEIVLD 174
           +VLQAD GTR A IT A +ALADA               P+   V+A + G ++G  +LD
Sbjct: 118 DVLQADGGTRTAAITGAYVALADAVAWAQGRKLIKANRKPLTGTVSAVSVGIVDGTPLLD 177

Query: 175 LNKEEDNYGEADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQK 229
           L  EED   + D+ V       D   +++ G        +DE    + LA  G   + + 
Sbjct: 178 LRYEEDVRADTDMNVV---CTGDGRFVEVQGTAEAEPFARDELNTLLDLATAGCTELAEL 234

Query: 230 QREAL 234
           QR+AL
Sbjct: 235 QRKAL 239


>pir||D70200 polyribonucleotide nucleotidyltransferase (pnpA) homolog - Lyme
           disease spirochete >gi|2688743|gb|AAC67149.1| (AE001179)
           polyribonucleotide nucleotidyltransferase (pnpA)
           [Borrelia burgdorferi]
           Length = 722
           
 Score = 81.1 bits (197), Expect = 1e-14
 Identities = 72/214 (33%), Positives = 108/214 (49%), Gaps = 14/214 (6%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPD---RA 73
           R DGR   E+R I  EV +L   +GSA    G+ + +A       +  + +   D   R 
Sbjct: 316 RTDGRTPNEIRDIISEVDILSRTHGSALFTRGETQALAVTTLGTSIDEQIMDDIDGDKRL 375

Query: 74  ILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEM-FPRTAIDVFIEVLQA 132
              + YN  PFSV E  +    RR I    + + ALE  +  +  FP T I V  EVL++
Sbjct: 376 NFMLHYNFPPFSVGETGRLMTGRREIGHGHLAQRALESMVPGKNDFPYT-IRVVSEVLES 434

Query: 133 DAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEADVP 188
           +  + +A + A S++L  AG+P++  VA  A G I EG+   ++ D+  EED+ G+ D  
Sbjct: 435 NGSSSMATVCAGSMSLMSAGVPVKGQVAGIAMGLISEGDKYVVLSDILGEEDHLGDMDFK 494

Query: 189 VAIMPLKNDITLLQMD---GYLTKDEFIEAVKLA 219
           VA    KN IT  QMD     +TKD   +A++ A
Sbjct: 495 VA--GTKNGITGFQMDIKIENVTKDLMRDALEQA 526


>pir||D82350 ribonuclease PH VC0210 [imported] - Vibrio cholerae (group O1
           strain N16961) >gi|9654617|gb|AAF93386.1| (AE004111)
           ribonuclease PH [Vibrio cholerae]
           Length = 257
           
 Score = 81.1 bits (197), Expect = 1e-14
 Identities = 65/239 (27%), Positives = 111/239 (46%), Gaps = 25/239 (10%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R D R   ++RPIK+       A GS  +E+G  K++       E  P+ L+   +  + 
Sbjct: 21  RPDNRAADQVRPIKITRHYTAYAEGSVLVEFGNTKVLCNA-SIEEGVPRWLKGQGKGWVT 79

Query: 77  VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y M P +   R +          R++EI ++I  +L   + LE      I V  +V+Q
Sbjct: 80  AEYGMLPRATHSRTRREATNGKQGGRTMEIQRLIARSLRAVVDLEAMGEIMITVDCDVIQ 139

Query: 132 ADAGTRVAGITAASLALADAGI-----------PMRDLVAACAAGKIEGEIVLDLNKEED 180
           AD GTR A IT AS+ALADA             PM+  VAA + G +  +++ DL   ED
Sbjct: 140 ADGGTRTASITGASVALADAFAHLIAKGQLKKNPMKGHVAAVSVGILGEDVLCDLEYVED 199

Query: 181 NYGEADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQKQREAL 234
           +  + D+ V    +  +  ++++ G       + ++ +E + +A KG   +   Q+ +L
Sbjct: 200 SAADTDMNVV---MTEEGKMIEIQGTAEGEPFSHEQLLELLAVAKKGIADIVAVQKASL 255


>pir||H65106 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain
           - Escherichia coli
           Length = 734
           
 Score = 80.8 bits (196), Expect = 1e-14
 Identities = 72/224 (32%), Positives = 115/224 (51%), Gaps = 20/224 (8%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPRE----LHPKHLQRPD 71
           RIDGR+K  +R + +  GVL   +GSA    G+ + ++ A  G       L     +R D
Sbjct: 338 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTD 397

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129
             +    YN  P+SV E    G P RR I   ++ K G L     ++ FP T + V  E+
Sbjct: 398 TFLFH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYT-VRVVSEI 454

Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185
            +++  + +A +  ASLAL DAG+P++  VA  A G + EG+   ++ D+  +ED+ G+ 
Sbjct: 455 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDM 514

Query: 186 DVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAV 226
           D  VA    ++ I+ LQMD     +TK E ++      KGA+ +
Sbjct: 515 DFKVA--GSRDGISALQMDIKIEGITK-EIMQVALNQAKGARLI 555


>gb|AAA57967.1| (U18997) polynucleotide phosphorylase [Escherichia coli]
           >gi|1789555|gb|AAC76198.1| (AE000397) polynucleotide
           phosphorylase; cytidylate kinase activity [Escherichia
           coli K12]
           Length = 734
           
 Score = 80.4 bits (195), Expect = 2e-14
 Identities = 66/199 (33%), Positives = 104/199 (52%), Gaps = 16/199 (8%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPRE----LHPKHLQRPD 71
           RIDGR+K  +R + +  GVL   +GSA    G+ + ++ A  G       L     +R D
Sbjct: 338 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTD 397

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129
             +    YN  P+SV E    G P RR I   ++ K G L     ++ FP T + V  E+
Sbjct: 398 TFLFH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYT-VRVVSEI 454

Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185
            +++  + +A +  ASLAL DAG+P++  VA  A G + EG+   ++ D+  +ED+ G+ 
Sbjct: 455 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDM 514

Query: 186 DVPVAIMPLKNDITLLQMD 204
           D  VA    ++ I+ LQMD
Sbjct: 515 DFKVA--GSRDGISALQMD 531


>sp|P05055|PNP_ECOLI POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE
           PHOSPHORYLASE) (PNPASE)
           Length = 711
           
 Score = 80.4 bits (195), Expect = 2e-14
 Identities = 66/199 (33%), Positives = 104/199 (52%), Gaps = 16/199 (8%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPRE----LHPKHLQRPD 71
           RIDGR+K  +R + +  GVL   +GSA    G+ + ++ A  G       L     +R D
Sbjct: 315 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTD 374

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129
             +    YN  P+SV E    G P RR I   ++ K G L     ++ FP T + V  E+
Sbjct: 375 TFLFH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYT-VRVVSEI 431

Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185
            +++  + +A +  ASLAL DAG+P++  VA  A G + EG+   ++ D+  +ED+ G+ 
Sbjct: 432 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDM 491

Query: 186 DVPVAIMPLKNDITLLQMD 204
           D  VA    ++ I+ LQMD
Sbjct: 492 DFKVA--GSRDGISALQMD 508


>emb|CAA71697.1| (Y10692) pnp [Yersinia enterocolitica]
           Length = 711
           
 Score = 80.4 bits (195), Expect = 2e-14
 Identities = 65/199 (32%), Positives = 103/199 (51%), Gaps = 16/199 (8%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGP----RELHPKHLQRPD 71
           RIDGR+K  +R + +  GVL   +GSA    G+ + ++ A  G     + +     +R D
Sbjct: 320 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQNIDELMGERTD 379

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129
             +L   YN  P+SV E    G P RR I   ++ K G L        FP T + V  E+
Sbjct: 380 SFLLH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPSPSEFPYT-VRVVSEI 436

Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEEDNYGEA 185
            +++  + +A +  ASLAL DAG+P++  VA  A G ++ +    ++ D+  +ED+ G+ 
Sbjct: 437 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEDENFVVLSDILGDEDHLGDM 496

Query: 186 DVPVAIMPLKNDITLLQMD 204
           D  VA    ++ IT LQMD
Sbjct: 497 DFKVA--GSRDGITALQMD 513


>sp|O34275|PNP_YEREN POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE
           PHOSPHORYLASE) (PNPASE)
           Length = 706
           
 Score = 80.4 bits (195), Expect = 2e-14
 Identities = 65/199 (32%), Positives = 103/199 (51%), Gaps = 16/199 (8%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGP----RELHPKHLQRPD 71
           RIDGR+K  +R + +  GVL   +GSA    G+ + ++ A  G     + +     +R D
Sbjct: 315 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQNIDELMGERTD 374

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129
             +L   YN  P+SV E    G P RR I   ++ K G L        FP T + V  E+
Sbjct: 375 SFLLH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPSPSEFPYT-VRVVSEI 431

Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEEDNYGEA 185
            +++  + +A +  ASLAL DAG+P++  VA  A G ++ +    ++ D+  +ED+ G+ 
Sbjct: 432 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEDENFVVLSDILGDEDHLGDM 491

Query: 186 DVPVAIMPLKNDITLLQMD 204
           D  VA    ++ IT LQMD
Sbjct: 492 DFKVA--GSRDGITALQMD 508


>gi|9910360 exosome component Rrp46 [Homo sapiens]
           >gi|11424056|ref|XP_008911.1| exosome component Rrp46
           [Homo sapiens] >gi|8927592|gb|AAF82135.1|AF281134_1
           (AF281134) exosome component Rrp46 [Homo sapiens]
           Length = 235
           
 Score = 80.0 bits (194), Expect = 2e-14
 Identities = 64/221 (28%), Positives = 110/221 (48%), Gaps = 20/221 (9%)

Query: 26  LRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFS 85
           LR    E  +L   +GSA    G   ++A VYGP E+           + +  +N A   
Sbjct: 28  LRHFACEQNLLSRPDGSASFLQGDTSVLAGVYGPAEVK----------VSKEIFNKATLE 77

Query: 86  VEERKK---PGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGTRVAG-I 141
           V  R K   PG   +S E  ++I+   E  ++  + PRT+I V ++V+ +DAG+ +A  +
Sbjct: 78  VILRPKIGLPGVAEKSRE--RLIRNTCEAVVLGTLHPRTSITVVLQVV-SDAGSLLACCL 134

Query: 142 TAASLALADAGIPMRDLV--AACAAGKIEGEIVLDLNKEEDNYGEADVPVAIMPLKNDIT 199
            AA +AL DAG+PMR L    ACA    +G +VLD   +++    A +  A+  ++  + 
Sbjct: 135 NAACMALVDAGVPMRALFCGVACALDS-DGTLVLDPTSKQEKEARAVLTFALDSVERKLL 193

Query: 200 LLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK 240
           +    G  +  E  + +  A   ++ V++  RE+L+ +Y K
Sbjct: 194 MSSTKGLYSDTELQQCLAAAQAASQHVFRFYRESLQRRYSK 234


>sp|Q9ZD43|PNP_RICPR POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE
           PHOSPHORYLASE) (PNPASE) >gi|7447101|pir||B71654
           polyribonucleotide nucleotidyltransferase (pnp) RP504 -
           Rickettsia prowazekii >gi|3861056|emb|CAA14956.1|
           (AJ235272) POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE
           (pnp) [Rickettsia prowazekii]
           Length = 745
           
 Score = 79.6 bits (193), Expect = 3e-14
 Identities = 64/224 (28%), Positives = 118/224 (52%), Gaps = 12/224 (5%)

Query: 9   KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPR--ELHPK 65
           K++++N  RIDGR   ++R I  EVG+L +A+GSA    G+ + +++  +G    E    
Sbjct: 309 KILEKN-IRIDGRSTTDIRQIACEVGLLPSAHGSALFTRGETQSLVSTTFGTSLDEQIVD 367

Query: 66  HLQRPDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEMFPRTAID 124
            L+   +    + Y   P+SV E      P RR +   K+   A+ P L  ++    +I 
Sbjct: 368 SLEGEYKERFMLNYIFPPYSVNEAMPMKAPSRREVGHGKLAWRAINPILPNKVQFPYSIR 427

Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEED 180
           V  E  +++  + +A +  +SLAL  AG+P++  VA  A G ++      ++ D+  +ED
Sbjct: 428 VVAETTESNGSSSMATVCGSSLALMHAGVPIKAPVAGIAMGLVKESNKFAVLSDIIGDED 487

Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAK 224
            +G+ D  VA     + IT LQMD  ++  +F + +++A++ A+
Sbjct: 488 YFGDMDFKVA--GTSSGITALQMDIKISGIDF-KIIQIALEQAR 528


>pir||A81866 tRNA nucleotidyltransferase (EC 2.7.7.56) - Neisseria meningitidis
           (group A strain Z2491) >gi|7380343|emb|CAB84930.1|
           (AL162756) ribonuclease PH [Neisseria meningitidis
           Z2491]
           Length = 242
           
 Score = 79.6 bits (193), Expect = 3e-14
 Identities = 71/228 (31%), Positives = 107/228 (46%), Gaps = 21/228 (9%)

Query: 26  LRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFS 85
           LR IK+    L + +GS  IE G  K+I        + P  L+  ++  +   Y M P S
Sbjct: 14  LRDIKITPHFLPHTDGSCLIECGNTKVICTASIDENV-PPFLRGKNQGWVTAEYGMLPAS 72

Query: 86  VEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGTRVAG 140
              R +          R+ EI ++I  +L   + +E      I +  +V+QAD GTR A 
Sbjct: 73  TASRMRREASAGKQSGRTQEIQRLIGRSLRAVVDMEKLGERQILIDCDVIQADGGTRTAS 132

Query: 141 ITAASLALADA-------GI----PMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADVPV 189
           IT A +AL  A       GI    P+R+ VAA + G + G  +LDL+  ED+  ++DV +
Sbjct: 133 ITGAFVALQIAVGKLVSDGILSENPIREAVAAVSVGVVNGVPLLDLDYPEDSGCDSDVNI 192

Query: 190 AIMPLKNDITLLQ---MDGYLTKDEFIEAVKLAIKGAKAVYQKQREAL 234
            +M     I  +Q    D   + DE  + V LA KG   + Q Q+ AL
Sbjct: 193 -VMTASGKIIEIQGTAEDAPFSLDELGKLVALAQKGIGELLQHQQNAL 239


>sp|P41121|PNP_PHOLU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE
           PHOSPHORYLASE) (PNPASE) (CAP87K) >gi|7447092|pir||S38883
           polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) -
           Xenorhabdus luminescens >gi|561531|emb|CAA53671.1|
           (X76069) polynucleotide phosphorylase [Photorhabdus
           luminescens]
           Length = 709
           
 Score = 79.2 bits (192), Expect = 4e-14
 Identities = 67/199 (33%), Positives = 102/199 (50%), Gaps = 16/199 (8%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPRE----LHPKHLQRPD 71
           RIDGR+K  +R + +  GVL   +GSA    G+ + ++ A  G       +     +R D
Sbjct: 315 RIDGREKDMVRALDVRTGVLPRTHGSALFTRGETQALVTATLGTERDAQIIDELMGERTD 374

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129
           R +L   YN  P+SV E    G P RR I   ++ K G L        FP T + V  E+
Sbjct: 375 RFLLH--YNFPPYSVGETGMMGSPKRREIGHGRLAKRGVLAVMPKANEFPYT-VRVVSEI 431

Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185
            +++  + +A +  ASLAL DAG+P++  VA  A G + EG+   ++ D+  +ED+ G+ 
Sbjct: 432 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNFVVLSDILGDEDHLGDM 491

Query: 186 DVPVAIMPLKNDITLLQMD 204
           D  VA       I+ LQMD
Sbjct: 492 DFKVA--GSCEGISALQMD 508


>pir||G81076 ribonuclease PH NMB1499 [imported] - Neisseria meningitidis  (group
           B strain MD58) >gi|7226741|gb|AAF41855.1| (AE002499)
           ribonuclease PH [Neisseria meningitidis MC58]
           Length = 242
           
 Score = 79.2 bits (192), Expect = 4e-14
 Identities = 73/231 (31%), Positives = 109/231 (46%), Gaps = 27/231 (11%)

Query: 26  LRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFS 85
           LR IK+    L + +GS  IE G  K+I        + P  L+  ++  +   Y M P S
Sbjct: 14  LRDIKITPHFLPHTDGSCLIECGNTKVICTASIDENV-PPFLRGKNQGWVTAEYGMLPAS 72

Query: 86  VEER--------KKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGTR 137
              R        K+ G   R+ EI ++I  +L   + +E      I +  +V+QAD GTR
Sbjct: 73  TASRMLREASAGKQSG---RTQEIQRLIGRSLRAVVDMEKLGERQILIDCDVIQADGGTR 129

Query: 138 VAGITAASLALADA-------GI----PMRDLVAACAAGKIEGEIVLDLNKEEDNYGEAD 186
            A IT A +AL  A       GI    P+R+ VAA + G + G  +LDL+  ED+  ++D
Sbjct: 130 TASITGAFVALQIAVGKLVSDGILSENPIREAVAAVSVGVVNGVPLLDLDYPEDSGCDSD 189

Query: 187 VPVAIMPLKNDITLLQ---MDGYLTKDEFIEAVKLAIKGAKAVYQKQREAL 234
           V + +M     I  +Q    D   + DE  + V LA KG   + Q Q+ AL
Sbjct: 190 VNI-VMTASGKIIEIQGTAEDAPFSLDELGKLVALAQKGIGELLQHQQNAL 239


>pir||T49262 hypothetical protein F12M12.180 - Arabidopsis thaliana
           >gi|7799009|emb|CAB90948.1| (AL355775) putative protein
           [Arabidopsis thaliana]
           Length = 239
           
 Score = 79.2 bits (192), Expect = 4e-14
 Identities = 54/165 (32%), Positives = 80/165 (47%), Gaps = 10/165 (6%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R DGR   +LRP+     +L   +GSA    G  K++AAVYGP+    K+ +  ++A   
Sbjct: 5   REDGRTPNQLRPLACSRNILHRPHGSASWSQGDTKVLAAVYGPKAGTKKN-ENAEKACFE 63

Query: 77  VRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGT 136
           V +      + + +K        E   ++K  ++   +L + P T   V I+V+  D   
Sbjct: 64  VIWKPKSGQIGKVEK--------EYEMILKRTIQSICVLTVNPNTTTSVIIQVVHDDGSL 115

Query: 137 RVAGITAASLALADAGIPMRDL-VAACAAGKIEGEIVLDLNKEED 180
               I AA  AL DAGIPM+ L VA C      G +VLD NK E+
Sbjct: 116 LPCAINAACAALVDAGIPMKHLAVAICCCLAENGYLVLDPNKLEE 160


>prf||2208281A 100RNP protein [Spinacia oleracea]
           Length = 779
           
 Score = 78.8 bits (191), Expect = 6e-14
 Identities = 75/245 (30%), Positives = 118/245 (47%), Gaps = 22/245 (8%)

Query: 9   KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK-- 65
           K I E GRR DGR    +RPI    G+L  A+GSA    G+ + +A V  G +++  +  
Sbjct: 427 KRIVEGGRRSDGRTSEGVRPINSRCGLLPRAHGSALFTRGETQALAVVTLGDKQMAQRID 486

Query: 66  HLQRPDRA-ILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILE-MFPRTA 122
            L+  D +    ++Y+  P  V E  + G P RR I    + + ALEP L  E  FP T 
Sbjct: 487 TLEGDDESKRFYLQYSFPPSCVGEAGRVGAPSRREIGHGTLAERALEPILPSEDEFPYT- 545

Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IV 172
           + V   + +++  + +A +   SLAL DAG+P++  +A  A G +        +G   I+
Sbjct: 546 VRVESNITESNGSSSMASVCGGSLALLDAGVPVKCPIAGIAMGMVLDTKEFGGDGTPLIL 605

Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229
            D+   ED  G+ D  VA     + +T  QMD   G +T     +A+  A  G K +  +
Sbjct: 606 SDITGSEDASGDMDFKVA--GNADCVTAFQMDIKVGGITLSVMKQALLQAKDGRKIILAE 663

Query: 230 QREAL 234
             + L
Sbjct: 664 MSKCL 668


>gb|AAC49669.1| (U52048) polyribonucleotide phophorylase [Spinacia oleracea]
           Length = 822
           
 Score = 78.8 bits (191), Expect = 6e-14
 Identities = 75/245 (30%), Positives = 118/245 (47%), Gaps = 22/245 (8%)

Query: 9   KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK-- 65
           K I E GRR DGR    +RPI    G+L  A+GSA    G+ + +A V  G +++  +  
Sbjct: 429 KRIVEGGRRSDGRTSEGVRPINSRCGLLPRAHGSALFTRGETQALAVVTLGDKQMAQRID 488

Query: 66  HLQRPDRA-ILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILE-MFPRTA 122
            L+  D +    ++Y+  P  V E  + G P RR I    + + ALEP L  E  FP T 
Sbjct: 489 TLEGDDESKRFYLQYSFPPSCVGEAGRVGAPSRREIGHGTLAERALEPILPSEDEFPYT- 547

Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IV 172
           + V   + +++  + +A +   SLAL DAG+P++  +A  A G +        +G   I+
Sbjct: 548 VRVESNITESNGSSSMASVCGGSLALLDAGVPVKCPIAGIAMGMVLDTKEFGGDGTPLIL 607

Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229
            D+   ED  G+ D  VA     + +T  QMD   G +T     +A+  A  G K +  +
Sbjct: 608 SDITGSEDASGDMDFKVA--GNADCVTAFQMDIKVGGITLSVMKQALLQAKDGRKIILAE 665

Query: 230 QREAL 234
             + L
Sbjct: 666 MSKCL 670


>pir||S64680 exoribonuclease 100 RNP - spinach
           Length = 779
           
 Score = 78.8 bits (191), Expect = 6e-14
 Identities = 75/245 (30%), Positives = 118/245 (47%), Gaps = 22/245 (8%)

Query: 9   KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK-- 65
           K I E GRR DGR    +RPI    G+L  A+GSA    G+ + +A V  G +++  +  
Sbjct: 427 KRIVEGGRRSDGRTSEGVRPINSRCGLLPRAHGSALFTRGETQALAVVTLGDKQMAQRID 486

Query: 66  HLQRPDRA-ILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILE-MFPRTA 122
            L+  D +    ++Y+  P  V E  + G P RR I    + + ALEP L  E  FP T 
Sbjct: 487 TLEGDDESKRFYLQYSFPPSCVGEAGRVGAPSRREIGHGTLAERALEPILPSEDEFPYT- 545

Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IV 172
           + V   + +++  + +A +   SLAL DAG+P++  +A  A G +        +G   I+
Sbjct: 546 VRVESNITESNGSSSMASVCGGSLALLDAGVPVKCPIAGIAMGMVLDTKEFGGDGTPLIL 605

Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229
            D+   ED  G+ D  VA     + +T  QMD   G +T     +A+  A  G K +  +
Sbjct: 606 SDITGSEDASGDMDFKVA--GNADCVTAFQMDIKVGGITLSVMKQALLQAKDGRKIILAE 663

Query: 230 QREAL 234
             + L
Sbjct: 664 MSKCL 668


>pir||G75320 polynucleotide phosphorylase - Deinococcus radiodurans  (strain R1)
           >gi|6459851|gb|AAF11608.1|AE002042_3 (AE002042)
           polynucleotide phosphorylase [Deinococcus radiodurans]
           Length = 810
           
 Score = 78.8 bits (191), Expect = 6e-14
 Identities = 76/247 (30%), Positives = 116/247 (46%), Gaps = 19/247 (7%)

Query: 2   MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRE 61
           +EK E  +LI E   R DGR    +RPI +E   L  A+GSA    G+ +++       E
Sbjct: 335 VEKRELRRLILEENLRADGRDSKTVRPIWIEARPLPTAHGSAVFTRGETQVLGVTTLGTE 394

Query: 62  -----LHPKHLQRPDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPAL-I 114
                +     +  D+ +L   YN  P+S  E K+  G  RR I    + K A+   L  
Sbjct: 395 RDEILIDDLTAESGDKFLL--HYNFPPYSTGEVKRMGGQSRREIGHGNLAKRAIRAVLPS 452

Query: 115 LEMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE--- 170
            E FP   I V  +VL+++  + +  + A +L+L DAG+P++  VA  A G + EG+   
Sbjct: 453 FEEFP-YVIRVVGDVLESNGSSSMGTVCAGTLSLMDAGVPLKAPVAGVAMGLVMEGDNYR 511

Query: 171 IVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVY 227
           ++ D+   ED  G+ D  V        +T LQMD   G +T     EA+  A +G   + 
Sbjct: 512 VLTDILGLEDALGDMDFKVC--GTAEGVTALQMDIKVGGITPQIMREALAQAKEGRLHIL 569

Query: 228 QKQREAL 234
            K  E L
Sbjct: 570 GKMAEVL 576


>pir||C82673 ribonuclease PH XF1505 [imported] - Xylella fastidiosa  (strain
           9a5c) >gi|9106537|gb|AAF84314.1|AE003980_6 (AE003980)
           ribonuclease PH [Xylella fastidiosa]
           Length = 241
           
 Score = 77.3 bits (187), Expect = 2e-13
 Identities = 68/242 (28%), Positives = 106/242 (43%), Gaps = 25/242 (10%)

Query: 14  NGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRA 73
           N  R  GR+   LRP+++E     +A GS  + +G N ++          P  L+     
Sbjct: 2   NVSRPSGRQADALRPVRIERAFTCHAEGSVLVSFG-NTLVVCTASVEAKVPVFLRNKGEG 60

Query: 74  ILRVRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIE 128
            +   Y M P S   R +    R     R++EI ++I  AL   +         I +  +
Sbjct: 61  WVTAEYGMLPRSTHTRSEREAARGKQAGRTLEIQRLIGRALRTCVDRTALGERTITLDCD 120

Query: 129 VLQADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNK 177
           VLQAD GTR A IT A +AL DA             P+   VAA + G   G  VLDL+ 
Sbjct: 121 VLQADGGTRTAAITGAYVALVDAVRCLEQRGQLKKSPLIGAVAAVSVGIYRGMPVLDLDY 180

Query: 178 EEDNYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEA-----VKLAIKGAKAVYQKQRE 232
            ED+  + D+ V    + ++  ++++ G   +  F        + LA +G   ++  QRE
Sbjct: 181 PEDSDCDTDMNVV---MNDEGGVIELQGTAEQQAFRRGELDMLLALAERGTAMLFDIQRE 237

Query: 233 AL 234
           AL
Sbjct: 238 AL 239


>pir||A26118 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain
           - Escherichia coli >gi|551833|gb|AAA83905.1| (J02638)
           polynucleotide phosphorilase [Escherichia coli]
           Length = 711
           
 Score = 76.9 bits (186), Expect = 2e-13
 Identities = 65/199 (32%), Positives = 104/199 (51%), Gaps = 16/199 (8%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK--IIAAVYGPRE---LHPKHLQRPD 71
           RIDGR+K  +R + +  GVL   +GSA    G+ +  + A +   R+   L     +R D
Sbjct: 315 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLRTARDAQVLDELMGERTD 374

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129
             +    YN  P+SV E    G P RR I   ++ K G L     ++ FP T + V  E+
Sbjct: 375 TFLFH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYT-VRVVSEI 431

Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185
            +++  + +A +  ASLA  DAG+P++  VA  A G + EG+   ++ D+  +ED+ G+ 
Sbjct: 432 TESNGSSSMASVCGASLASMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDM 491

Query: 186 DVPVAIMPLKNDITLLQMD 204
           D  VA    ++ I+ LQMD
Sbjct: 492 DFKVA--GSRDGISALQMD 508


>pir||E82298 polyribonucleotide nucleotidyltransferase VC0647 [imported] -
           Vibrio cholerae (group O1 strain N16961)
           >gi|9655083|gb|AAF93813.1| (AE004150) polyribonucleotide
           nucleotidyltransferase [Vibrio cholerae]
           Length = 709
           
 Score = 76.9 bits (186), Expect = 2e-13
 Identities = 71/236 (30%), Positives = 117/236 (49%), Gaps = 21/236 (8%)

Query: 2   MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPR 60
           +EK    + I     RIDGR+K  +R + +  GVL   +GSA    G+ + ++ A  G +
Sbjct: 301 LEKTVVRRSIIAGNPRIDGREKDMVRALDVRTGVLPRTHGSALFTRGETQALVTATLGTQ 360

Query: 61  E----LHPKHLQRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALIL 115
                +     ++ D  +L   YN  P+ V E    G P RR I   ++ K  +   +  
Sbjct: 361 RDAQIIDELTGEKKDHFLLH--YNFPPYCVGETGFVGSPKRREIGHGRLAKRGIAAVMPS 418

Query: 116 -EMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE---- 170
            E FP T + V  E+ +++  + +A +  +SLAL DAG+P++  VA  A G ++ E    
Sbjct: 419 PEEFPYT-VRVVSEITESNGSSSMASVCGSSLALMDAGVPIKASVAGIAMGLVKEENDFV 477

Query: 171 IVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLTKDEFI--EAVKLAIKGAK 224
           ++ D+  +ED+ G+ D  VA       +T LQMD    K E I  E +++A+  AK
Sbjct: 478 VLSDILGDEDHLGDMDFKVA--GTATGVTALQMD---IKIEGITKEIMQIALNQAK 528


>pir||C71269 probable polyribonucleotide nucleotidyltransferase (pnp) - syphilis
           spirochete >gi|3323203|gb|AAC26576.1| (AE001258)
           polyribonucleotide nucleotidyltransferase (pnp)
           [Treponema pallidum]
           Length = 702
           
 Score = 76.5 bits (185), Expect = 3e-13
 Identities = 65/201 (32%), Positives = 100/201 (49%), Gaps = 13/201 (6%)

Query: 13  ENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV----YGPRELHPKHLQ 68
           + G RIDGR    +RPI  EVGVL   +GSA    G+ + +A V        +++   ++
Sbjct: 310 DRGLRIDGRAIDAIRPIACEVGVLPRPHGSAVFTRGETQSLAVVTLGAMSDGQVY-DDIE 368

Query: 69  RPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFI 127
              R    + YN  PFSV E  + G  RR I    +   +L   +   E FP T + V  
Sbjct: 369 GDRRENFILHYNFPPFSVGEIGRMGVGRREIGHGCLAHRSLSAVIPDPEQFPYT-VRVVS 427

Query: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEG----EIVLDLNKEEDNYG 183
           E+L+++  + +A + + +L+L  AG+P++  VA  A G I       I+ D+  EED+ G
Sbjct: 428 EILESNGSSSMATVCSGTLSLLHAGVPIKKPVAGIAMGLITDGVRYAILSDILGEEDHLG 487

Query: 184 EADVPVAIMPLKNDITLLQMD 204
           + D  VA     + IT  QMD
Sbjct: 488 DMDFKVA--GTCDGITGFQMD 506


>pir||H69190 conserved hypothetical protein MTH682 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621767|gb|AAB85187.1| (AE000848) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 271
           
 Score = 76.1 bits (184), Expect = 4e-13
 Identities = 57/238 (23%), Positives = 106/238 (43%), Gaps = 33/238 (13%)

Query: 14  NGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRA 73
           N  RIDGR  +E R I +E GV+  A GS+ ++ G  +II  V    ++       P+  
Sbjct: 22  NKERIDGRSLHEFRDISIETGVISKAEGSSRVKLGNTQIIVGV--KPQIGEPFPDTPEMG 79

Query: 74  ILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAID--------V 125
           ++     + P +    +   PD RS+E+S+V+   +  + ++++     I+        +
Sbjct: 80  VILTNSELLPMASPTFEPGPPDERSVELSRVVDRCIRESRMIDLEKLCIIEGSKVWMLFL 139

Query: 126 FIEVLQADAGTRVAGITAASLALADAGIPMRDL--------------------VAACAAG 165
            + ++  D     A + A   AL D  IP  ++                       C   
Sbjct: 140 DLHIIDYDGNLFDAAVLATVAALLDTRIPAAEVEDGEVVINREKMQPLPVNRKALMCTFA 199

Query: 166 KIEGEIVLDLNKEEDNYGEADVPVAIMPLKNDITLLQM--DGYLTKDEFIEAVKLAIK 221
           KI  EIVLD + EE++   A + + +   +  I  +Q   +G LT+D+ ++AV +A++
Sbjct: 200 KIGNEIVLDPSLEEEDILTARISIGVTE-EGSICAMQKGGEGPLTRDDVLKAVSIAVE 256


>pir||G81725 polyribonucleotide nucleotidyltransferase TC0230 [imported] -
           Chlamydia muridarum (strain Nigg)
           >gi|7190270|gb|AAF39102.1| (AE002290) polyribonucleotide
           nucleotidyltransferase [Chlamydia muridarum]
           Length = 693
           
 Score = 75.3 bits (182), Expect = 6e-13
 Identities = 64/204 (31%), Positives = 99/204 (48%), Gaps = 12/204 (5%)

Query: 10  LIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRELHPK--H 66
           LI + G R+DGR   E+RPI +EV  L   +GS     G+ + +A    G   +  +   
Sbjct: 307 LIRDLGIRVDGRSTTEIRPISIEVSFLPRTHGSCLFTRGETQSVAVCTLGGESMAQRFED 366

Query: 67  LQRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAID 124
           L     A   ++Y   PFSV E  + G P RR I   K+ + AL   L     FP T + 
Sbjct: 367 LNGDGAARFYLQYFFPPFSVGEVGRIGSPGRREIGHGKLAEKALSHVLPEASRFPYT-VR 425

Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI----EGEIVLDLNKEED 180
           V   + +++  + +A +    L+L DAG+P++  VA  A G I    +  ++ D++  ED
Sbjct: 426 VESNITESNGSSSMASVCGGCLSLMDAGVPIKAPVAGIAMGLILDQDKAIVLSDISGIED 485

Query: 181 NYGEADVPVAIMPLKNDITLLQMD 204
           + G+ D  VA    +  IT  QMD
Sbjct: 486 HLGDMDFKVA--GTEEGITAFQMD 507


>pir||F82831 polynucleotide phosphorylase XF0239 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9105050|gb|AAF83052.1|AE003877_7
           (AE003877) polynucleotide phosphorylase [Xylella
           fastidiosa]
           Length = 719
           
 Score = 75.3 bits (182), Expect = 6e-13
 Identities = 63/197 (31%), Positives = 98/197 (48%), Gaps = 12/197 (6%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPD---RA 73
           RIDGR    +RPI ++VGVL   +GS     G+ + I           + +       + 
Sbjct: 335 RIDGRSLEAVRPITVKVGVLPRVHGSGLFTRGETQAIVVTTLGTARDGQVIDAVTGEYKE 394

Query: 74  ILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEVLQ 131
                YN  P+SV E  + G P RR I   ++ + G L     L+ FP T I V  E+ +
Sbjct: 395 NFLFHYNFPPYSVGECGRFGVPKRREIGHGRLARRGVLAVMPSLDEFPYT-IRVVSEITE 453

Query: 132 ADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEADV 187
           ++  + +A +  +SLAL DAG+P++  VA  A G + EGE   ++ D+  +ED+ G+ D 
Sbjct: 454 SNGSSSMASVCGSSLALMDAGVPVKAPVAGIAMGLVKEGERFVVLSDILGDEDHLGDMDF 513

Query: 188 PVAIMPLKNDITLLQMD 204
            VA       ++ LQMD
Sbjct: 514 KVA--GTSEGVSALQMD 528


>sp|P44584|PNP_HAEIN POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE
           PHOSPHORYLASE) (PNPASE) >gi|1075159|pir||E64056
           polyribonucleotide nucleotidyltransferase (EC 2.7.7.8)
           alpha chain - Haemophilus influenzae (strain Rd KW20)
           >gi|1573193|gb|AAC21898.1| (U32709) polynucleotide
           phosphorylase (pnp) [Haemophilus influenzae Rd]
           Length = 709
           
 Score = 75.3 bits (182), Expect = 6e-13
 Identities = 68/222 (30%), Positives = 110/222 (48%), Gaps = 21/222 (9%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL-----QRPD 71
           RIDGR    +R + +  GVL   +GSA    G+ + +A      E   + +     +R D
Sbjct: 314 RIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGERQD 373

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEV 129
             +    YN  P+SV E    G P RR I   ++ K  +   +  L  FP   + V  E+
Sbjct: 374 HFLFH--YNFPPYSVGETGMIGSPKRREIGHGRLAKRGVAAVMPSLAEFPYV-VRVVSEI 430

Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEEDNYGEA 185
            +++  + +A +  ASLAL DAG+P++  VA  A G ++ E    ++ D+  +ED+ G+ 
Sbjct: 431 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDM 490

Query: 186 DVPVAIMPLKNDITLLQMDGYLTKDEFI--EAVKLAIKGAKA 225
           D  VA    +  +T LQMD    K E I  E +++A+  AK+
Sbjct: 491 DFKVA--GTREGVTALQMD---IKIEGITPEIMQIALNQAKS 527


>sp|Q9ZCT5|RNPH_RICPR RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE)
           >gi|7435287|pir||C71668 ribonuclease ph (rph) RP628 -
           Rickettsia prowazekii >gi|3861169|emb|CAA15069.1|
           (AJ235272) RIBONUCLEASE PH (rph) [Rickettsia prowazekii]
           Length = 240
           
 Score = 75.3 bits (182), Expect = 6e-13
 Identities = 67/239 (28%), Positives = 107/239 (44%), Gaps = 25/239 (10%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R  GRK  +LRPI +E+  L NA GS  I+ G   ++ +      + P  L+  ++  + 
Sbjct: 2   RQSGRKSNQLRPISLELSPLINAEGSCLIKIGNTHVMCSATCETTV-PPFLRGQNQGWIT 60

Query: 77  VRYNMAPFSVEERKK-----PGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y M P S   R K          R+ EI ++I  A+   + L+      I +  +V+ 
Sbjct: 61  AEYGMIPGSTSHRIKREAALGKQGGRTQEIQRLIGRAMRCVINLQKLGERQIIIDCDVIN 120

Query: 132 ADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEED 180
           AD GTR A IT + +AL  A             P+   +AA + G  +G  VLDL+  ED
Sbjct: 121 ADGGTRTAAITGSYVALHLAIRSLMKKRILKVNPLISQIAAISCGIYKGNAVLDLDYLED 180

Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTK-----DEFIEAVKLAIKGAKAVYQKQREAL 234
           +  E D         N   L+++ G   K     ++F+  +KLA  G   +++ Q + L
Sbjct: 181 SDAEVDSNFVFACNGN---LIEVQGTAEKEPFSEEQFLAMLKLAKSGVVELFKLQNQVL 236


>pir||T48631 polynucleotide phosphorylase - Arabidopsis thaliana
           >gi|4971998|emb|CAB43864.1| (Y14685) polynucleotide
           phosphorylase [Arabidopsis thaliana]
           >gi|4972000|emb|CAB43865.1| (Y14686) polynucleotide
           phosphorylase [Arabidopsis thaliana]
           >gi|7573307|emb|CAB87625.1| (AL163792) polynucleotide
           phosphorylase [Arabidopsis thaliana]
           Length = 991
           
 Score = 74.9 bits (181), Expect = 8e-13
 Identities = 66/207 (31%), Positives = 99/207 (46%), Gaps = 19/207 (9%)

Query: 14  NGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVY--GPRELHP-KHLQRP 70
           +G R+DGR   E+RPI  E   L   +GSA    G  +++  V    P E      L  P
Sbjct: 361 DGFRVDGRHVDEVRPIYCESHYLPALHGSALFSRGDTQVLCTVTLGAPAEAQSLDSLVGP 420

Query: 71  DRAILRVRYNMAPFSVEE-RKKPGPDRRSIEISKVIKGALEPALILE-MFPRTAIDVFIE 128
            +    + Y+  P+   E  K+ G +RR +    + + AL   L  E  FP T I +  E
Sbjct: 421 PKKRFMLHYSFPPYCTNEVGKRGGLNRREVGHGTLAEKALLAVLPPEEAFPYT-IRINSE 479

Query: 129 VLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI------EGE-----IVLDLNK 177
           V+ +D  T +A +   S+AL DAGIP+R  VA  + G I       GE     IV D+  
Sbjct: 480 VMSSDGSTSMASVCGGSMALMDAGIPLRAHVAGVSVGLITDVDPSSGEIKDYRIVTDILG 539

Query: 178 EEDNYGEADVPVAIMPLKNDITLLQMD 204
            ED+ G+ D  +A    ++ +T +Q+D
Sbjct: 540 LEDHLGDMDFKIA--GTRDGVTAIQLD 564


>pir||T50343 low homolog to ribonuclease ph-like protein [imported] - fission
           yeast (Schizosaccharomyces pombe)
           >gi|6983772|emb|CAB75416.1| (AL139314) low similarity to
           ribonuclease ph-like protein [Schizosaccharomyces pombe]
           Length = 257
           
 Score = 74.9 bits (181), Expect = 8e-13
 Identities = 47/135 (34%), Positives = 74/135 (54%), Gaps = 4/135 (2%)

Query: 27  RPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFSV 86
           R I +++G    A GS+Y E  K KI   V GPR    K       A L   + ++PFS 
Sbjct: 36  RKIYLKLGWATKAVGSSYFESEKIKIACTVSGPRP--SKTFAFRSSAKLNCEFRLSPFST 93

Query: 87  EERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADA--GTRVAGITAA 144
             R+           S++I+ A+ P+++L ++P+++IDV+I+V+++D    T  A I+ A
Sbjct: 94  SVRQGHVQTVEEKSYSQMIEAAISPSILLHLYPKSSIDVYIQVIESDGALATLAAAISCA 153

Query: 145 SLALADAGIPMRDLV 159
           S A+ADA I   DLV
Sbjct: 154 SSAIADANIDCIDLV 168


>gb|AAD28218.1|AF120720_1 (AF120720) ribonuclease PH [Legionella pneumophila]
           Length = 235
           
 Score = 74.5 bits (180), Expect = 1e-12
 Identities = 54/191 (28%), Positives = 91/191 (47%), Gaps = 17/191 (8%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76
           R   R+  +LRP+ +       A GS  +E+G+ K+I       E  P+ L+  ++  + 
Sbjct: 2   RPSNREHDQLRPVTITRNFTNYAEGSVLVEFGQTKVICNA-SIVEGVPRFLKGKNQGWIT 60

Query: 77  VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131
             Y M P +   R +    +     R++EI ++I  +L   + L++     I +  +V+Q
Sbjct: 61  AEYGMLPRATHSRTEREASKGKQGGRTLEIQRLIGRSLRACIDLKVLGENTITLDCDVIQ 120

Query: 132 ADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEED 180
           AD GTR A IT + +A+ DA            +P  + VAA + G   G+ VLDL+  ED
Sbjct: 121 ADGGTRTAAITGSCVAMRDAIHWMVQREKIKKMPAFNYVAAVSVGIYRGQPVLDLDYAED 180

Query: 181 NYGEADVPVAI 191
              E D+ V +
Sbjct: 181 VLAETDMNVVM 191


>gb|AAF68421.1|AF237935_1 (AF237935) polynucleotide phosphorylase [Pasteurella multocida]
           Length = 684
           
 Score = 74.5 bits (180), Expect = 1e-12
 Identities = 67/222 (30%), Positives = 110/222 (49%), Gaps = 21/222 (9%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL-----QRPD 71
           RIDGR    +R + +  GVL   +GSA    G+ + +A      E   + +     +R D
Sbjct: 287 RIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGERSD 346

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEV 129
             +    YN  P+SV E    G P RR I   ++ K  +   +  L  FP   + V  E+
Sbjct: 347 HFLFH--YNFPPYSVGETGMIGSPKRREIGHGRLAKRGVAAVMPTLAEFPYV-VRVVSEI 403

Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEEDNYGEA 185
            +++  + +A +  ASLAL DAG+P++  VA  A G ++ +    ++ D+  +ED+ G+ 
Sbjct: 404 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEDEKFVVLSDILGDEDHLGDM 463

Query: 186 DVPVAIMPLKNDITLLQMDGYLTKDEFI--EAVKLAIKGAKA 225
           D  VA    +  +T LQMD    K E I  E +++A+  AK+
Sbjct: 464 DFKVA--GTRTGVTALQMD---IKIEGITAEIMQIALNQAKS 500


>pir||B75378 ribonuclease PH - Deinococcus radiodurans (strain R1)
           >gi|6459349|gb|AAF11146.1|AE002002_4 (AE002002)
           ribonuclease PH [Deinococcus radiodurans]
           Length = 246
           
 Score = 73.7 bits (178), Expect = 2e-12
 Identities = 57/185 (30%), Positives = 91/185 (48%), Gaps = 15/185 (8%)

Query: 19  DGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVR 78
           +GR     RP+ ++ GV  +A GSA+++ G+ +I+A V    +  P H++      L   
Sbjct: 10  EGRDALTPRPVSVQRGVNPHAPGSAHLKMGRTEILATVTLDDKPAP-HMRGKKEGWLTAE 68

Query: 79  YNMAPFSVEERK---KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAG 135
           Y+M P S  +R+   +   + R  EI +++  AL  ++ L  F    + V  +VL AD G
Sbjct: 69  YSMLPRSTTDRQARERNLQNGRRHEIQRLLGRALRSSMDLRPFKNQTLYVDCDVLVADGG 128

Query: 136 TRVAGITAASLALAD-----------AGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGE 184
           TRVA + A   AL D           +  P+   V A + G I  E+ +DL+ EED    
Sbjct: 129 TRVASVLAGHAALHDFCDRLINSGQLSEWPIVHNVGAISVGLIGDELRVDLDYEEDKVAR 188

Query: 185 ADVPV 189
           AD+ V
Sbjct: 189 ADLNV 193


>emb|CAA20272.1| (AL031231) guanosine pentaphosphate synthetase/ polyribonucleotide
           nucleotidyltransferase [Streptomyces coelicolor A3(2)]
           Length = 716
           
 Score = 73.4 bits (177), Expect = 2e-12
 Identities = 69/217 (31%), Positives = 102/217 (46%), Gaps = 19/217 (8%)

Query: 16  RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72
           +RIDGR   ++R +  EV  +   +GSA  E G+ +I+          E     L    R
Sbjct: 338 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTR 397

Query: 73  AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130
                 YN  P+SV E  + G P RR I    + + A+ P L   E FP  AI    E L
Sbjct: 398 KRYMHNYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 456

Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182
            ++  T +  + A++++L +AG+P++  VA  A G I  EI        + D+   ED +
Sbjct: 457 GSNGSTSMGSVCASTMSLLNAGVPLKAPVAGIAMGLISQEINGETHYVALTDILGAEDAF 516

Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219
           G+ D  VA    K  +T LQ+D   TK + I A  LA
Sbjct: 517 GDMDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 548


>pir||T10932 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain
           [similarity] - Streptomyces coelicolor
           Length = 739
           
 Score = 73.4 bits (177), Expect = 2e-12
 Identities = 69/217 (31%), Positives = 102/217 (46%), Gaps = 19/217 (8%)

Query: 16  RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72
           +RIDGR   ++R +  EV  +   +GSA  E G+ +I+          E     L    R
Sbjct: 338 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTR 397

Query: 73  AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130
                 YN  P+SV E  + G P RR I    + + A+ P L   E FP  AI    E L
Sbjct: 398 KRYMHNYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 456

Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182
            ++  T +  + A++++L +AG+P++  VA  A G I  EI        + D+   ED +
Sbjct: 457 GSNGSTSMGSVCASTMSLLNAGVPLKAPVAGIAMGLISQEINGETHYVALTDILGAEDAF 516

Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219
           G+ D  VA    K  +T LQ+D   TK + I A  LA
Sbjct: 517 GDMDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 548


>pdb|1E3P|A Chain A, Tungstate Derivative Of Streptomyces Antibioticus Pnpase
           Gpsi Enzyme
           Length = 757
           
 Score = 73.4 bits (177), Expect = 2e-12
 Identities = 69/217 (31%), Positives = 102/217 (46%), Gaps = 19/217 (8%)

Query: 16  RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72
           +RIDGR   ++R +  EV  +   +GSA  E G+ +I+          E     L    R
Sbjct: 355 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTR 414

Query: 73  AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130
                 YN  P+SV E  + G P RR I    + + A+ P L   E FP  AI    E L
Sbjct: 415 KRYMHNYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 473

Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182
            ++  T +  + A++++L +AG+P++  VA  A G I  EI        + D+   ED +
Sbjct: 474 GSNGSTSMGSVCASTMSLLNAGVPLKAPVAGIAMGLISQEINGETHYVALTDILGAEDAF 533

Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219
           G+ D  VA    K  +T LQ+D   TK + I A  LA
Sbjct: 534 GDMDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 565


>pir||T44900 probable polyribonucleotide nucleotidyltransferase (EC 2.7.7.8)
           [imported] - Mycobacterium leprae
           >gi|2342619|emb|CAB11392.1| (Z98741) guanosine
           pentaphosphate synthetase/ polyribonucleotide
           nucleotidyltransferase [Mycobacterium leprae]
           Length = 777
           
 Score = 73.0 bits (176), Expect = 3e-12
 Identities = 64/208 (30%), Positives = 99/208 (46%), Gaps = 20/208 (9%)

Query: 14  NGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQR--PD 71
           N  RIDGR   ++R +  EV V+  A+GSA  E G+ +I+           + +    P+
Sbjct: 354 NHFRIDGRGITDIRALSAEVAVVPRAHGSALFERGETQILGVTTLDMVKMAQQIDSLGPE 413

Query: 72  RAILRVR-YNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIE 128
            +   +  YN  PFS  E  + G P RR I    + + AL P L  +E FP  AI    E
Sbjct: 414 TSKRYMHHYNFPPFSTGETGRVGSPKRREIGHGALAERALVPVLPSVEEFPY-AIRQVSE 472

Query: 129 VLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKE---------- 178
            L ++  T +  + A++LAL +AG+P++  VA  A G +  ++  D   E          
Sbjct: 473 ALGSNGSTSMGSVCASTLALLNAGVPLKAPVAGIAMGLVSDDVEFDGGTERRFVTLTDIL 532

Query: 179 --EDNYGEADVPVAIMPLKNDITLLQMD 204
             ED +G+ D   A    K+ +T LQ+D
Sbjct: 533 GAEDAFGDMDFKCA--GTKDFVTALQLD 558


>gb|AAF00646.1|AC009540_23 (AC009540) putative polynucleotide phosphorylase [Arabidopsis
           thaliana] >gi|6091752|gb|AAF03462.1|AC009327_1
           (AC009327) putative polynucleotide phosphorylase
           [Arabidopsis thaliana]
           Length = 948
           
 Score = 72.6 bits (175), Expect = 4e-12
 Identities = 74/234 (31%), Positives = 116/234 (48%), Gaps = 26/234 (11%)

Query: 11  IDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK--HL 67
           I E G+R DGR   E+RPI    G+L  A+GS     G+ + +A V  G +++  +  +L
Sbjct: 467 IVEGGKRSDGRTLDEIRPINSRCGLLPRAHGSTLFTRGETQALAVVTLGDKQMAQRIDNL 526

Query: 68  QRPDR-AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALIL-EMFPRTAID 124
           +  D      ++Y   P SV E  + G P RR I    + + ALE  L   + FP T I 
Sbjct: 527 EGSDEYKRFYLQYTFPPSSVGEVGRIGAPSRREIGHGTLAERALETILPSDDDFPYT-IR 585

Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IVLD 174
           V   V++++  + +A +    LAL DAG+P++  VA  A G +        +G   I+ D
Sbjct: 586 VESTVIESNGSSSMASVCGGCLALQDAGVPVKCSVAGIAMGMVWDTEEFGGDGSPLILSD 645

Query: 175 LNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKA 225
           +   ED  G+ D  VA    ++ +T  QMD   G +T    +E ++ A+  AKA
Sbjct: 646 ITGAEDASGDMDFKVA--GNEDGVTAFQMDIKVGGIT----LEIMEKALIQAKA 693


>emb|CAB85703.1| (AJ252123) putative polynucleotide phosphorylase [Arabidopsis
           thaliana]
           Length = 922
           
 Score = 72.6 bits (175), Expect = 4e-12
 Identities = 74/234 (31%), Positives = 116/234 (48%), Gaps = 26/234 (11%)

Query: 11  IDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK--HL 67
           I E G+R DGR   E+RPI    G+L  A+GS     G+ + +A V  G +++  +  +L
Sbjct: 441 IVEGGKRSDGRTLDEIRPINSRCGLLPRAHGSTLFTRGETQALAVVTLGDKQMAQRIDNL 500

Query: 68  QRPDR-AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALIL-EMFPRTAID 124
           +  D      ++Y   P SV E  + G P RR I    + + ALE  L   + FP T I 
Sbjct: 501 EGSDEYKRFYLQYTFPPSSVGEVGRIGAPSRREIGHGTLAERALETILPSDDDFPYT-IR 559

Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IVLD 174
           V   V++++  + +A +    LAL DAG+P++  VA  A G +        +G   I+ D
Sbjct: 560 VESTVIESNGSSSMASVCGGCLALQDAGVPVKCSVAGIAMGMVWDTEEFGGDGSPLILSD 619

Query: 175 LNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKA 225
           +   ED  G+ D  VA    ++ +T  QMD   G +T    +E ++ A+  AKA
Sbjct: 620 ITGAEDASGDMDFKVA--GNEDGVTAFQMDIKVGGIT----LEIMEKALIQAKA 667


>gb|AAB17498.1| (U19858) guanosine pentaphosphate synthetase [Streptomyces
           antibioticus]
           Length = 740
           
 Score = 72.2 bits (174), Expect = 5e-12
 Identities = 69/217 (31%), Positives = 101/217 (45%), Gaps = 19/217 (8%)

Query: 16  RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72
           +RIDGR   ++R +  EV  +   +GSA  E G+ +I+          E     L    R
Sbjct: 338 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTR 397

Query: 73  AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130
                 YN  P SV E  + G P RR I    + + A+ P L   E FP  AI    E L
Sbjct: 398 KPYMHNYNFPPISVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 456

Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182
            ++  T +  + A++++L +AG+P++  VA  A G I  EI        + D+   ED +
Sbjct: 457 GSNGSTSMGSVCASTMSLLNAGVPLKAPVAGIAMGLISQEINGETHYVALTDILGAEDAF 516

Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219
           G+ D  VA    K  +T LQ+D   TK + I A  LA
Sbjct: 517 GDMDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 548


>pir||F70883 probable guanosine pentaphosphate synthetase and polyribonucleotide
           nucleotidyltransferase - Mycobacterium tuberculosis
           (strain H37RV) >gi|2624305|emb|CAA15578.1| (AL008967)
           gpsI [Mycobacterium tuberculosis]
           Length = 752
           
 Score = 72.2 bits (174), Expect = 5e-12
 Identities = 64/209 (30%), Positives = 100/209 (47%), Gaps = 24/209 (11%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQR--PDRAI 74
           RIDGR   ++R +  EV V+  A+GSA  E G+ +I+           + +    P+ + 
Sbjct: 346 RIDGRGITDIRALSAEVAVVPRAHGSALFERGETQILGVTTLDMIKMAQQIDSLGPETSK 405

Query: 75  LRVR-YNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVLQ 131
             +  YN  PFS  E  + G P RR I    + + AL P L  +E FP  AI    E L 
Sbjct: 406 RYMHHYNFPPFSTGETGRVGSPKRREIGHGALAERALVPVLPSVEEFPY-AIRQVSEALG 464

Query: 132 ADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI----------------VLDL 175
           ++  T +  + A++LAL +AG+P++  VA  A G +  +I                + D+
Sbjct: 465 SNGSTSMGSVCASTLALLNAGVPLKAPVAGIAMGLVSDDIQVEGAVDGVVERRFVTLTDI 524

Query: 176 NKEEDNYGEADVPVAIMPLKNDITLLQMD 204
              ED +G+ D  VA    K+ +T LQ+D
Sbjct: 525 LGAEDAFGDMDFKVA--GTKDFVTALQLD 551


>pdb|1E3H|A Chain A, Semet Derivative Of Streptomyces Antibioticus PnpaseGPSI
           Enzyme
           Length = 757
           
 Score = 72.2 bits (174), Expect = 5e-12
 Identities = 69/217 (31%), Positives = 100/217 (45%), Gaps = 19/217 (8%)

Query: 16  RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72
           +RIDGR   ++R +  EV  +   +GSA  E G+ +I+          E     L    R
Sbjct: 355 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNXLRXEQQLDTLSPVTR 414

Query: 73  AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130
                 YN  P+SV E  + G P RR I    + + A+ P L   E FP  AI    E L
Sbjct: 415 KRYXHNYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 473

Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182
            ++  T    + A++ +L +AG+P++  VA  A G I  EI        + D+   ED +
Sbjct: 474 GSNGSTSXGSVCASTXSLLNAGVPLKAPVAGIAXGLISQEINGETHYVALTDILGAEDAF 533

Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219
           G+ D  VA    K  +T LQ+D   TK + I A  LA
Sbjct: 534 GDXDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 565


>pir||E71463 probable polyribonucleotide nucleotidyltransferase - Chlamydia
           trachomatis (serotype D, strain UW3/Cx)
           >gi|3329314|gb|AAC68439.1| (AE001357) Polyribonucleotide
           Nucleotidyltransferase [Chlamydia trachomatis]
           Length = 695
           
 Score = 71.0 bits (171), Expect = 1e-11
 Identities = 64/208 (30%), Positives = 97/208 (45%), Gaps = 20/208 (9%)

Query: 10  LIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRELHPK--H 66
           LI + G R+DGR   E+RPI +E   L   +GS     G+ + +A    G   +  +   
Sbjct: 308 LIQDLGIRVDGRTTTEIRPISIETPFLPRTHGSCLFTRGETQSMAVCTLGGENMAQRFED 367

Query: 67  LQRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILEMFPRTAIDV 125
           L     A   ++Y   PFSV E  + G P RR I   K+ + AL   L     P T+   
Sbjct: 368 LNGDGAARFYLQYFFPPFSVGEVGRIGSPGRREIGHGKLAEKALSHVL-----PETSRFP 422

Query: 126 FI-----EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI----EGEIVLDLN 176
           +I      + +++  + +A +    LAL DAG+P++  VA  A G I    +  I+ D++
Sbjct: 423 YIIRLESNITESNGSSSMASVCGGCLALMDAGVPIKAPVAGIAMGLILDRDQAIILSDIS 482

Query: 177 KEEDNYGEADVPVAIMPLKNDITLLQMD 204
             ED+ G+ D  VA       IT  QMD
Sbjct: 483 GIEDHLGDMDFKVA--GTAKGITAFQMD 508


>pir||T06540 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) - garden pea
           >gi|2286200|gb|AAC50039.1| (AF010578) polynucleotide
           phosphorylase [Pisum sativum]
           Length = 897
           
 Score = 70.6 bits (170), Expect = 2e-11
 Identities = 71/245 (28%), Positives = 115/245 (45%), Gaps = 22/245 (8%)

Query: 9   KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRELHPK-- 65
           K I E G+R DGR   E+RPI     +L  A+GSA    G+ + +A A  G  ++  +  
Sbjct: 436 KRIVEGGKRSDGRTPKEIRPINSSCSILPRAHGSALFTRGETQALAVATLGDNKMAQRIN 495

Query: 66  -HLQRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILEM-FPRTA 122
             ++  D     ++Y+  P  V E  + G P RR I    + + +LE  L  +  FP T 
Sbjct: 496 NLIEVDDYKRFYLQYSFPPSCVGEAGRIGAPSRREIGHGMLAERSLETILPSDNDFPYT- 554

Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IV 172
           I V   + +++  + +A +    LAL DAG+P++  +A  A G +        +G   I+
Sbjct: 555 IRVESTITESNGSSSMASVCGGCLALQDAGVPIKCSIAGIAMGLVLDTKEFGGDGTPLIL 614

Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229
            D+   ED  G+ D  VA    ++ IT  QMD     +T     EA+  A  G K +  +
Sbjct: 615 SDITGSEDASGDMDFKVA--GNEDGITAFQMDIKVAGITLPIMREALLQARDGRKHILGE 672

Query: 230 QREAL 234
             ++L
Sbjct: 673 MMKSL 677


>pir||H81943 probable polyribonucleotide nucleotidyltransferase (EC 2.7.7.8)
           NMA0969 [imported] - Neisseria meningitidis (group A
           strain Z2491) >gi|7379672|emb|CAB84239.1| (AL162754)
           putative polyribonucleotide nucleotidyltransferase
           [Neisseria meningitidis Z2491]
           Length = 706
           
 Score = 70.6 bits (170), Expect = 2e-11
 Identities = 61/198 (30%), Positives = 95/198 (47%), Gaps = 14/198 (7%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRE----LHPKHLQRPD 71
           RIDGR    +RP+ ++ GVL   +GSA    G+ + +A A  G       +     +  D
Sbjct: 316 RIDGRDTRTVRPLNIQTGVLPRTHGSALFTRGETQALAVATLGTSRDEQIIDALSGEYTD 375

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVL 130
           R +L   YN  P+S  E  + G P RR I   ++ K AL   L         + V  E+ 
Sbjct: 376 RFML--HYNFPPYSTGEVGRMGAPKRREIGHGRLAKRALLAVLPKPEDFSYTMRVVSEIT 433

Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEAD 186
           +++  + +A +    L+L  AG+P++  VA  A G I EG    ++ D+  +ED+ G+ D
Sbjct: 434 ESNGSSSMASVCGGCLSLLSAGVPLKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMD 493

Query: 187 VPVAIMPLKNDITLLQMD 204
             VA       +T LQMD
Sbjct: 494 FKVA--GTTEGVTALQMD 509


>pir||E64671 polynucleotide phosphorylase - Helicobacter pylori (strain 26695)
           >gi|2314375|gb|AAD08258.1| (AE000627) polynucleotide
           phosphorylase (pnp) [Helicobacter pylori 26695]
           Length = 688
           
 Score = 69.5 bits (167), Expect = 4e-11
 Identities = 72/248 (29%), Positives = 117/248 (47%), Gaps = 17/248 (6%)

Query: 2   MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPR 60
           ++K E  ++I ++  R D R   E+RPI +E  +L  A+ S     G+ + ++  V G  
Sbjct: 299 VKKTEIRRMIIKDKIRPDKRALEEVRPILIESDLLPMAHSSILFTRGQTQSLVVGVLGTD 358

Query: 61  ELHPKHLQRPDRAILRVR----YNMAPFSVEERKKPGP-DRRSIEISKVIKGALEPALIL 115
                H     +A ++ R    YN  PF V E    G   RR +    + K ALE ++  
Sbjct: 359 NDAQTHESLEHKAPIKERFMFHYNFPPFCVGEASSIGAASRRELGHGNLAKRALETSIKN 418

Query: 116 EMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---I 171
           +      I +  E+L+++  + +A + A SLAL  +G+ + DLVA  A G + EG+   I
Sbjct: 419 K---EQVIRLVSEILESNGSSSMASVCAGSLALYASGVEIYDLVAGVAMGMVSEGQDHAI 475

Query: 172 VLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLT--KDEFIEAVKLAIKGAKAVYQK 229
           + D++  ED  G+ D  +A       IT +QMD  ++  K E +    L  K A+    K
Sbjct: 476 LSDISGLEDAEGDMDFKIA--GNLEGITAMQMDTKMSGIKLEILYQALLQAKEARKHILK 533

Query: 230 QREALKEK 237
                KEK
Sbjct: 534 IMHEAKEK 541


>pir||G72009 polyribonucleotide nucleotidyltransferase CP0855 [imported] -
           Chlamydophila pneumoniae (strains CWL029 and AR39)
           >gi|4377328|gb|AAD19136.1| (AE001680) Polyribonucleotide
           Nucleotidyltransferase [Chlamydophila pneumoniae CWL029]
           >gi|7189766|gb|AAF38644.1| (AE002244) polyribonucleotide
           nucleotidyltransferase [Chlamydophila pneumoniae AR39]
           >gi|8979372|dbj|BAA99206.1| (AP002548)
           polyribonucleotide nucleotidyltransferase [Chlamydophila
           pneumoniae J138]
           Length = 694
           
 Score = 69.5 bits (167), Expect = 4e-11
 Identities = 70/246 (28%), Positives = 112/246 (45%), Gaps = 15/246 (6%)

Query: 10  LIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAA-VYGPRELHPKHLQ 68
           LI +   R DGR    +RPI +E   L   +GS     G+ + +A    G   +  ++  
Sbjct: 308 LIRDREIRADGRSLTTVRPITIETSYLPRTHGSCLFTRGETQTLAVCTLGSEAMAQRYED 367

Query: 69  RPDRAILR--VRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALI-LEMFPRTAID 124
                + +  ++Y   PFSV E  + G P RR I   K+ + AL  AL     FP T I 
Sbjct: 368 LNGEGLSKFYLQYFFPPFSVGEVGRIGSPGRREIGHGKLAEKALSHALPDSATFPYT-IR 426

Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI---EGEIVL-DLNKEED 180
           +   + +++  + +A +    LAL DAG+P+   +A  A G I   +G I+L D++  ED
Sbjct: 427 IESNITESNGSSSMASVCGGCLALMDAGVPISSPIAGIAMGLILDDQGAIILSDISGLED 486

Query: 181 NYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQKQREALKEK 237
           + G+ D  +A       IT  QMD     +T     +A+  A +G   +     EAL   
Sbjct: 487 HLGDMDFKIA--GSGKGITAFQMDIKVEGITPAIMKKALSQAKQGCNDILNIMNEALSAP 544

Query: 238 YLKIAQ 243
              ++Q
Sbjct: 545 KADLSQ 550


>pir||E71845 polyribonucleotide nucleotidyltransferase - Helicobacter pylori
           (strain J99) >gi|4155738|gb|AAD06718.1| (AE001541)
           POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE [Helicobacter
           pylori J99]
           Length = 688
           
 Score = 68.3 bits (164), Expect = 8e-11
 Identities = 69/248 (27%), Positives = 115/248 (45%), Gaps = 17/248 (6%)

Query: 2   MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPR 60
           ++K E  ++I ++  R D R   E+RPI +E  +L  A+ S     G+ + ++  V G  
Sbjct: 299 VKKTEIRRMIIQDKIRPDKRALEEVRPISIESNLLPMAHSSILFTRGQTQSLVVGVLGMD 358

Query: 61  ELHPKHLQRPDRAILRVR----YNMAPFSVEERKKPGP-DRRSIEISKVIKGALEPALIL 115
                H     +A ++ R    YN  PF V E    G   RR +    + K ALE ++  
Sbjct: 359 NDAQTHENLEHKAPIKERFMFHYNFPPFCVGEASSIGATSRRELGHGNLAKRALETSIKN 418

Query: 116 EMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI----EGEI 171
           +      I +  E+L+++  + +A + A SLAL  +G+ + DLVA  A G +    +  I
Sbjct: 419 K---EQVIRLVSEILESNGSSSMASVCAGSLALYASGVEIHDLVAGVAMGMVSERQDHAI 475

Query: 172 VLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLT--KDEFIEAVKLAIKGAKAVYQK 229
           + D++  ED  G+ D  +A       IT +QMD  ++  + E +    L  K A+    K
Sbjct: 476 LSDISGLEDAEGDMDFKIA--GNLEGITAMQMDTKMSGIQLEVLYQALLQAKRARKHILK 533

Query: 230 QREALKEK 237
                KEK
Sbjct: 534 IMHEAKEK 541


>pir||C81161 polyribonucleotide nucleotidyltransferase NMB0758 [imported] -
           Neisseria meningitidis (group B strain MD58)
           >gi|7225988|gb|AAF41171.1| (AE002430) polyribonucleotide
           nucleotidyltransferase [Neisseria meningitidis MC58]
           Length = 707
           
 Score = 68.3 bits (164), Expect = 8e-11
 Identities = 60/198 (30%), Positives = 94/198 (47%), Gaps = 14/198 (7%)

Query: 17  RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRE----LHPKHLQRPD 71
           RIDGR    +RP+ ++  VL   +GSA    G+ + +A A  G       +     +  D
Sbjct: 317 RIDGRDTRTVRPLNIQTSVLPRTHGSALFTRGETQALAVATLGTSRDEQIIDALSGEYTD 376

Query: 72  RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVL 130
           R +L   YN  P+S  E  + G P RR I   ++ K AL   L         + V  E+ 
Sbjct: 377 RFML--HYNFPPYSTGEVGRMGAPKRREIGHGRLAKRALLAVLPKPEDFSYTMRVVSEIT 434

Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEAD 186
           +++  + +A +    L+L  AG+P++  VA  A G I EG    ++ D+  +ED+ G+ D
Sbjct: 435 ESNGSSSMASVCGGCLSLLSAGVPLKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMD 494

Query: 187 VPVAIMPLKNDITLLQMD 204
             VA       +T LQMD
Sbjct: 495 FKVA--GTTEGVTALQMD 510


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.317    0.137    0.379 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89261604
Number of Sequences: 2977
Number of extensions: 3668329
Number of successful extensions: 9866
Number of sequences better than 1.0e-10: 86
Number of HSP's better than  0.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 9718
Number of HSP's gapped (non-prelim): 110
length of query: 249
length of database: 189,106,746
effective HSP length: 58
effective length of query: 191
effective length of database: 154,394,500
effective search space: 29489349500
effective search space used: 29489349500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 164 (68.3 bits)