BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0420 (rph) DE:ribonuclease PH (rph) (249 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||E75181 ribonuclease ph (rph) PAB0420 - Pyrococcus abyssi (s... 491 e-138 pir||E71032 hypothetical protein PH1549 - Pyrococcus horikoshii ... 478 e-134 emb|CAC12415.1| (AL445067) RNase PH (yeast SIK6) related protein... 306 2e-82 gb|AAK41031.1| Ribonuclease PH (rph) [Sulfolobus solfataricus] 305 4e-82 emb|CAB57569.1| (Y18930) ribonuclease PH [Sulfolobus solfataricus] 305 4e-82 pir||A69191 tRNA nucleotidyltransferase (EC 2.7.7.56) - Methanob... 298 5e-80 gi|11498104 ribonuclease PH (rph) [Archaeoglobus fulgidus] >gi|7... 297 9e-80 pir||G72623 probable ribonuclease PH APE1447 - Aeropyrum pernix ... 272 3e-72 pir||T47954 exonuclease RRP41 [imported] - Arabidopsis thaliana ... 207 9e-53 gi|9506689 hypothetical protein [Homo sapiens] >gi|7020801|dbj|B... 183 2e-45 gb|AAF53263.1| (AE003639) CG15481 gene product [Drosophila melan... 148 7e-35 sp|Q17533|RNPH_CAEEL RIBONUCLEASE PH-LIKE PROTEIN B0564.1 >gi|38... 141 1e-32 pir||T11740 hypothetical protein - fission yeast (Schizosaccharo... 126 2e-28 pir||T11646 tRNA nucleotidyltransferase homolog - fission yeast ... 126 2e-28 gi|6321634 homolog of RNAse PH; Ski6p [Saccharomyces cerevisiae]... 115 5e-25 pir||E70320 polyribonucleotide nucleotidyltransferase - Aquifex ... 100 3e-20 sp|O67069|RNPH_AQUAE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY... 99 3e-20 pir||D82978 ribonuclease PH PA5334 [imported] - Pseudomonas aeru... 99 4e-20 sp|P03842|RNPH_ECOLI RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY... 94 1e-18 sp|P50597|RNPH_PSEAE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY... 94 2e-18 sp|P44444|RNPH_HAEIN RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY... 93 3e-18 pir||QQECPE tRNA nucleotidyltransferase (EC 2.7.7.56) - Escheric... 92 4e-18 pir||A72264 polynucleotide phosphorylase - Thermotoga maritima (... 92 8e-18 emb|CAB06341.1| (Z84207) polynucleotide phosphorylase [Thermus t... 91 1e-17 gb|AAF72714.1|AF263927_2 (AF263927) ribonuclease PH [Carnobacter... 91 1e-17 gb|AAA61996.1| (L10328) RNase PH [Escherichia coli] >gi|1790074|... 89 7e-17 sp|P28619|RNPH_BACSU RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY... 88 1e-16 sp|Q10628|RNPH_MYCTU PROBABLE RIBONUCLEASE PH (RNASE PH) (TRNA N... 88 1e-16 sp|O87792|PNP_PSEPU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P... 87 1e-16 pir||C83052 polyribonucleotide nucleotidyltransferase PA4740 [im... 87 1e-16 dbj|BAB06787.1| (AP001517) ribonuclease PH [Bacillus halodurans] 87 2e-16 pir||A44914 tRNA nucleotidyltransferase (EC 2.7.7.56) - Bacillus... 87 3e-16 pir||G81332 polyribonucleotide nucleotidyltransferase (EC 2.7.7.... 86 4e-16 sp|P37939|RNPH_MYCLE PROBABLE RIBONUCLEASE PH (RNASE PH) (TRNA N... 85 6e-16 sp|P50849|PNPA_BACSU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (... 85 1e-15 sp|P57454|PNP_BUCAI POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P... 85 1e-15 dbj|BAB06126.1| (AP001515) polynucleotide phosphorylase [Bacillu... 84 1e-15 pir||S74509 polyribonucleotide nucleotidyltransferase (EC 2.7.7.... 83 4e-15 pir||T36127 probable ribonuclease PH - Streptomyces coelicolor >... 83 4e-15 pir||D70200 polyribonucleotide nucleotidyltransferase (pnpA) hom... 81 1e-14 pir||D82350 ribonuclease PH VC0210 [imported] - Vibrio cholerae ... 81 1e-14 pir||H65106 polyribonucleotide nucleotidyltransferase (EC 2.7.7.... 81 1e-14 gb|AAA57967.1| (U18997) polynucleotide phosphorylase [Escherichi... 80 2e-14 sp|P05055|PNP_ECOLI POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P... 80 2e-14 emb|CAA71697.1| (Y10692) pnp [Yersinia enterocolitica] 80 2e-14 sp|O34275|PNP_YEREN POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P... 80 2e-14 gi|9910360 exosome component Rrp46 [Homo sapiens] >gi|11424056|r... 80 2e-14 sp|Q9ZD43|PNP_RICPR POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P... 80 3e-14 pir||A81866 tRNA nucleotidyltransferase (EC 2.7.7.56) - Neisseri... 80 3e-14 sp|P41121|PNP_PHOLU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P... 79 4e-14 pir||G81076 ribonuclease PH NMB1499 [imported] - Neisseria menin... 79 4e-14 pir||T49262 hypothetical protein F12M12.180 - Arabidopsis thalia... 79 4e-14 prf||2208281A 100RNP protein [Spinacia oleracea] 79 6e-14 gb|AAC49669.1| (U52048) polyribonucleotide phophorylase [Spinaci... 79 6e-14 pir||S64680 exoribonuclease 100 RNP - spinach 79 6e-14 pir||G75320 polynucleotide phosphorylase - Deinococcus radiodura... 79 6e-14 pir||C82673 ribonuclease PH XF1505 [imported] - Xylella fastidio... 77 2e-13 pir||A26118 polyribonucleotide nucleotidyltransferase (EC 2.7.7.... 77 2e-13 pir||E82298 polyribonucleotide nucleotidyltransferase VC0647 [im... 77 2e-13 pir||C71269 probable polyribonucleotide nucleotidyltransferase (... 76 3e-13 pir||H69190 conserved hypothetical protein MTH682 - Methanobacte... 76 4e-13 pir||G81725 polyribonucleotide nucleotidyltransferase TC0230 [im... 75 6e-13 pir||F82831 polynucleotide phosphorylase XF0239 [imported] - Xyl... 75 6e-13 sp|P44584|PNP_HAEIN POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (P... 75 6e-13 sp|Q9ZCT5|RNPH_RICPR RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDY... 75 6e-13 pir||T48631 polynucleotide phosphorylase - Arabidopsis thaliana ... 75 8e-13 pir||T50343 low homolog to ribonuclease ph-like protein [importe... 75 8e-13 gb|AAD28218.1|AF120720_1 (AF120720) ribonuclease PH [Legionella ... 75 1e-12 gb|AAF68421.1|AF237935_1 (AF237935) polynucleotide phosphorylase... 75 1e-12 pir||B75378 ribonuclease PH - Deinococcus radiodurans (strain R1... 74 2e-12 emb|CAA20272.1| (AL031231) guanosine pentaphosphate synthetase/ ... 73 2e-12 pir||T10932 polyribonucleotide nucleotidyltransferase (EC 2.7.7.... 73 2e-12 pdb|1E3P|A Chain A, Tungstate Derivative Of Streptomyces Antibio... 73 2e-12 pir||T44900 probable polyribonucleotide nucleotidyltransferase (... 73 3e-12 gb|AAF00646.1|AC009540_23 (AC009540) putative polynucleotide pho... 73 4e-12 emb|CAB85703.1| (AJ252123) putative polynucleotide phosphorylase... 73 4e-12 gb|AAB17498.1| (U19858) guanosine pentaphosphate synthetase [Str... 72 5e-12 pir||F70883 probable guanosine pentaphosphate synthetase and pol... 72 5e-12 pdb|1E3H|A Chain A, Semet Derivative Of Streptomyces Antibioticu... 72 5e-12 pir||E71463 probable polyribonucleotide nucleotidyltransferase -... 71 1e-11 pir||T06540 polyribonucleotide nucleotidyltransferase (EC 2.7.7.... 71 2e-11 pir||H81943 probable polyribonucleotide nucleotidyltransferase (... 71 2e-11 pir||E64671 polynucleotide phosphorylase - Helicobacter pylori (... 69 4e-11 pir||G72009 polyribonucleotide nucleotidyltransferase CP0855 [im... 69 4e-11 pir||E71845 polyribonucleotide nucleotidyltransferase - Helicoba... 68 8e-11 pir||C81161 polyribonucleotide nucleotidyltransferase NMB0758 [i... 68 8e-11 >pir||E75181 ribonuclease ph (rph) PAB0420 - Pyrococcus abyssi (strain Orsay) >gi|5458042|emb|CAB49532.1| (AJ248284) ribonuclease PH (rph) [Pyrococcus abyssi] Length = 249 Score = 491 bits (1251), Expect = e-138 Identities = 249/249 (100%), Positives = 249/249 (100%) Query: 1 MMEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPR 60 MMEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPR Sbjct: 1 MMEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPR 60 Query: 61 ELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR 120 ELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR Sbjct: 61 ELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR 120 Query: 121 TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED 180 TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED Sbjct: 121 TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED 180 Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK 240 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK Sbjct: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK 240 Query: 241 IAQEVEGSE 249 IAQEVEGSE Sbjct: 241 IAQEVEGSE 249 >pir||E71032 hypothetical protein PH1549 - Pyrococcus horikoshii >gi|3257978|dbj|BAA30661.1| (AP000006) 249aa long hypothetical protein [Pyrococcus horikoshii] Length = 249 Score = 478 bits (1218), Expect = e-134 Identities = 242/249 (97%), Positives = 247/249 (99%) Query: 1 MMEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPR 60 MMEKPEGLKLIDENGRRIDGRKKYELRPIKM+VGVLKNANGSAYIEWG+NKIIAAVYGPR Sbjct: 1 MMEKPEGLKLIDENGRRIDGRKKYELRPIKMKVGVLKNANGSAYIEWGRNKIIAAVYGPR 60 Query: 61 ELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR 120 ELH KHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR Sbjct: 61 ELHSKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPR 120 Query: 121 TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED 180 T+IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED Sbjct: 121 TSIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEED 180 Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK 240 NYGEADVPVAIMPLKNDITLLQMDGYLTK+EFIEAV+LAIKGAKAVYQKQREALKEKYLK Sbjct: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKEEFIEAVRLAIKGAKAVYQKQREALKEKYLK 240 Query: 241 IAQEVEGSE 249 IAQEVE SE Sbjct: 241 IAQEVEESE 249 >emb|CAC12415.1| (AL445067) RNase PH (yeast SIK6) related protein [Thermoplasma acidophilum] Length = 248 Score = 306 bits (775), Expect = 2e-82 Identities = 148/240 (61%), Positives = 189/240 (78%), Gaps = 1/240 (0%) Query: 8 LKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL 67 +KLI+E+ R+DGR ELRPIK++ GVL A+GSAYIEWG NKI+ VYGP+E +PKH Sbjct: 9 IKLINEDNLRLDGRSFNELRPIKIQAGVLNRADGSAYIEWGGNKIMVGVYGPKEAYPKHS 68 Query: 68 QRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFI 127 Q D AI++ RYNMA FSV+ERK+PGPDRR++EISKVI AL ++++E FPR IDV+I Sbjct: 69 QDIDHAIVKARYNMAAFSVDERKRPGPDRRTMEISKVISEALSSSIMIEQFPRAEIDVYI 128 Query: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADV 187 EVLQADAGTR+AG+TAA++ALADAG+PMRD+V C AGK++G +VLDL+KEEDNYGEAD+ Sbjct: 129 EVLQADAGTRIAGLTAATVALADAGVPMRDMVVGCTAGKVDGHMVLDLSKEEDNYGEADI 188 Query: 188 PVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQEVEG 247 P+AIMP DI L+QMDG +T+DE +A+ + + K + Q QREAL KY KI EG Sbjct: 189 PIAIMPKTGDIVLMQMDGDVTEDELYQAMDMIFEATKRISQIQREALLNKY-KIQDIGEG 247 >gb|AAK41031.1| Ribonuclease PH (rph) [Sulfolobus solfataricus] Length = 248 Score = 305 bits (772), Expect = 4e-82 Identities = 148/243 (60%), Positives = 191/243 (77%), Gaps = 3/243 (1%) Query: 2 MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRE 61 +E+P KLI ++G+R DGRK ELR IK+E+GVLKNA+GSA E G K IAAVYGP+E Sbjct: 7 VERP---KLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKE 63 Query: 62 LHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRT 121 +HP+HL PDRA+LRVRY+M PFS +ERK P P RR IE+SKVI+ ALE A+++E+FPRT Sbjct: 64 MHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRT 123 Query: 122 AIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDN 181 AIDVF E+LQADAG+R+ + AASLALADAGIPMRDL+A A GK +G I+LDLN+ ED Sbjct: 124 AIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDM 183 Query: 182 YGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKI 241 +GEAD+P+A+MP N +TL Q++G +T DEF +A LA+KG +Y +REALK KY++ Sbjct: 184 WGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEF 243 Query: 242 AQE 244 +E Sbjct: 244 KEE 246 >emb|CAB57569.1| (Y18930) ribonuclease PH [Sulfolobus solfataricus] Length = 248 Score = 305 bits (772), Expect = 4e-82 Identities = 148/243 (60%), Positives = 191/243 (77%), Gaps = 3/243 (1%) Query: 2 MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRE 61 +E+P KLI ++G+R DGRK ELR IK+E+GVLKNA+GSA E G K IAAVYGP+E Sbjct: 7 VERP---KLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKE 63 Query: 62 LHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRT 121 +HP+HL PDRA+LRVRY+M PFS +ERK P P RR IE+SKVI+ ALE A+++E+FPRT Sbjct: 64 MHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRT 123 Query: 122 AIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDN 181 AIDVF E+LQADAG+R+ + AASLALADAGIPMRDL+A A GK +G I+LDLN+ ED Sbjct: 124 AIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDM 183 Query: 182 YGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKI 241 +GEAD+P+A+MP N +TL Q++G +T DEF +A LA+KG +Y +REALK KY++ Sbjct: 184 WGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEF 243 Query: 242 AQE 244 +E Sbjct: 244 KEE 246 >pir||A69191 tRNA nucleotidyltransferase (EC 2.7.7.56) - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621768|gb|AAB85188.1| (AE000848) ribonuclease PH [Methanobacterium thermoautotrophicum] Length = 240 Score = 298 bits (754), Expect = 5e-80 Identities = 144/222 (64%), Positives = 183/222 (81%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R DGR ELRP+K+E G+L+ A+GS+Y+E+G NKI+ AVYGPRE + LQRPDRA++R Sbjct: 17 REDGRAFDELRPLKIEAGILERADGSSYLEFGGNKILVAVYGPREAQIRKLQRPDRAVIR 76 Query: 77 VRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGT 136 RYNMAPFSVEERK+PGPDRRS+EISK+ AL PALILE FPR+ IDVFIEVL+A+ GT Sbjct: 77 CRYNMAPFSVEERKRPGPDRRSVEISKITAEALRPALILEKFPRSVIDVFIEVLEAEGGT 136 Query: 137 RVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADVPVAIMPLKN 196 R AGITAAS+ALADAGIPMRD+V ACAAGK+ ++VLDL++EED G+ADVPVAI+P Sbjct: 137 RCAGITAASVALADAGIPMRDMVVACAAGKVGDQVVLDLSEEEDKEGQADVPVAILPRTR 196 Query: 197 DITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKY 238 +ITLLQ DG LT +EF A+ LA++G +++ Q+EAL+++Y Sbjct: 197 EITLLQSDGNLTPEEFERALDLAVEGCLRIHEVQKEALRKRY 238 >gi|11498104 ribonuclease PH (rph) [Archaeoglobus fulgidus] >gi|7435296|pir||E69311 ribonuclease PH (rph) homolog - Archaeoglobus fulgidus >gi|2650133|gb|AAB90744.1| (AE001070) ribonuclease PH (rph) [Archaeoglobus fulgidus] Length = 258 Score = 297 bits (752), Expect = 9e-80 Identities = 147/248 (59%), Positives = 197/248 (79%), Gaps = 8/248 (3%) Query: 3 EKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPREL 62 EKPE L ++D G R+DGRK ELRPIK+E VLK A+GS Y+E GKNK+IAAV+GPRE+ Sbjct: 6 EKPEKL-IVD--GLRLDGRKFDELRPIKIEASVLKRADGSCYLEMGKNKVIAAVFGPREV 62 Query: 63 HPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTA 122 HP+HLQ P +AI+R RYNMAPFSVEERK+PGPDRRSIEISKV K A E ++ E+FPR+A Sbjct: 63 HPRHLQDPSKAIIRYRYNMAPFSVEERKRPGPDRRSIEISKVSKEAFEAVIMKELFPRSA 122 Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNY 182 ID+F+EVLQADAG+R A + AAS+AL DAG+PM+ ++ + A GK +G++VLD KEEDN+ Sbjct: 123 IDIFVEVLQADAGSRTACLNAASVALVDAGVPMKGMITSVAVGKADGQLVLDPMKEEDNF 182 Query: 183 GEADVPVAIMPLKN----DITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKY 238 GEAD+P A + ++N I LLQMDG +T+DE +A++LA KGA +Y+ QREA+ +Y Sbjct: 183 GEADMPFAFL-IRNGKIESIALLQMDGRMTRDEVKQAIELAKKGALQIYEMQREAILRRY 241 Query: 239 LKIAQEVE 246 +++ +E++ Sbjct: 242 IEVGEEMD 249 >pir||G72623 probable ribonuclease PH APE1447 - Aeropyrum pernix (strain K1) >gi|5105131|dbj|BAA80445.1| (AP000061) 246aa long hypothetical ribonuclease PH [Aeropyrum pernix] Length = 246 Score = 272 bits (688), Expect = 3e-72 Identities = 133/235 (56%), Positives = 181/235 (76%), Gaps = 1/235 (0%) Query: 7 GLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKH 66 G++LI +GRR DGR +LRP++M+VG+L NA+GSA +E+G+ +++AAVYGPRE H + Sbjct: 8 GVELI-RDGRRHDGRLPEDLRPVRMQVGILHNADGSALVEFGRTRVLAAVYGPREPHQRF 66 Query: 67 LQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVF 126 PDRA LRVRY+MAPFS +ERK P P RR IE+SKV++ ALEP ++ E FPRT IDVF Sbjct: 67 YVLPDRAALRVRYHMAPFSTDERKSPAPSRREIELSKVVREALEPVVLAEEFPRTVIDVF 126 Query: 127 IEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEAD 186 +EVLQAD GTR A +TAASLALADAGIPMR LV A GKI+G +V+D+++ ED YGEAD Sbjct: 127 LEVLQADGGTRTAAVTAASLALADAGIPMRALVGGVAVGKIQGVLVVDVDELEDMYGEAD 186 Query: 187 VPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKI 241 +PVA P +ITLLQ++G LT +EF A+ +A++ V + ++EA+++ YL++ Sbjct: 187 MPVAAAPDIGEITLLQLNGVLTGEEFRTALAMALRAIDRVVEMEKEAIRKSYLEV 241 >pir||T47954 exonuclease RRP41 [imported] - Arabidopsis thaliana >gi|6164938|gb|AAF04590.1|AF191741_1 (AF191741) exonuclease RRP41 [Arabidopsis thaliana] >gi|6850853|emb|CAB71092.1| (AL132959) exonuclease RRP41 [Arabidopsis thaliana] Length = 241 Score = 207 bits (522), Expect = 9e-53 Identities = 109/230 (47%), Positives = 153/230 (66%), Gaps = 1/230 (0%) Query: 8 LKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL 67 ++ ++ G R+DGR+ E+R I EVGV+ A+GSA E G K+IAAVYGPRE+ K Sbjct: 1 MEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQ 60 Query: 68 QRP-DRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVF 126 Q+ D A++ Y+MA FS +R++ DRRS E+S VI+ +E ++ E+ P + ID+F Sbjct: 61 QKKNDHAVVLCEYSMAQFSTGDRRRQKFDRRSTELSLVIRQTMEACILTELMPHSQIDIF 120 Query: 127 IEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEAD 186 ++VLQAD GTR A I AA+LALADAGIPMRDL +C+AG + +LDLN ED+ G AD Sbjct: 121 LQVLQADGGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGAD 180 Query: 187 VPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKE 236 V V I+P + ++LLQMD L + F LA +G KA+ ++ RE L+E Sbjct: 181 VTVGILPKLDKVSLLQMDAKLPMETFETVFALASEGCKAIAERIREVLQE 230 >gi|9506689 hypothetical protein [Homo sapiens] >gi|7020801|dbj|BAA91279.1| (AK000598) unnamed protein product [Homo sapiens] >gi|8927590|gb|AAF82134.1|AF281133_1 (AF281133) exosome component Rrp41 [Homo sapiens] Length = 245 Score = 183 bits (459), Expect = 2e-45 Identities = 93/223 (41%), Positives = 142/223 (62%), Gaps = 2/223 (0%) Query: 7 GLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKH 66 GL+L+ + G R+DGR+ ELR I+ +GV A+GSAYIE G K +A VYGP E+ Sbjct: 3 GLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSR 62 Query: 67 LQR-PDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEMFPRTAID 124 + PDRA++ +Y+ A FS ERK+ P DR+S E+ ++ E A++ ++ PR+ ID Sbjct: 63 ARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQID 122 Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGE 184 ++++VLQAD GT A + AA+LA+ DAGIPMRD V AC+AG ++G + DL+ E+ G Sbjct: 123 IYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTALADLSHVEEAAGG 182 Query: 185 ADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVY 227 + +A++P I LL+MD L +D ++ A + A+ V+ Sbjct: 183 PQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVH 225 >gb|AAF53263.1| (AE003639) CG15481 gene product [Drosophila melanogaster] Length = 246 Score = 148 bits (369), Expect = 7e-35 Identities = 82/232 (35%), Positives = 131/232 (56%), Gaps = 6/232 (2%) Query: 10 LIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQR 69 L+ E G R+DGR+ +ELR IK ++GV + +GSAY+E G K++AAVYGP + + Sbjct: 7 LLSEQGLRLDGRRPHELRRIKCKLGVFEQPDGSAYMEQGNTKVLAAVYGPHQAKGNQTE- 65 Query: 70 PDRAILRVRYNMAPFSVEERK-KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIE 128 +++ +Y+ A FS ERK +P DR+S+E ++ AL A+ E++PR+ ID+++E Sbjct: 66 ---SVINCQYSQATFSTAERKNRPRGDRKSLEFKLYLQQALSAAIKSELYPRSQIDIYVE 122 Query: 129 VLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVL-DLNKEEDNYGEADV 187 VLQ D + AA+LAL DAGI + + + AC A + I L D+++ E+ G + Sbjct: 123 VLQDDGANYAVALNAATLALIDAGICLNEFIVACTASLSKSNIPLTDISQFEEVSGGPKL 182 Query: 188 PVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYL 239 VA +P I L+M D ++ A+ G + + A+KE L Sbjct: 183 TVAALPTAEKIAFLEMSERFHIDHLETVIETAMAGCREIRDILEAAVKEHLL 234 >sp|Q17533|RNPH_CAEEL RIBONUCLEASE PH-LIKE PROTEIN B0564.1 >gi|3873830|emb|CAA97771.3| (Z73422) Similarity to H.influenza ribonuclease PH (SW:RNPH_HAEIN), contains similarity to Pfam domain: PF01138 (3 exoribonuclease family), Score=263.9, E-value=7.1e-76, N=1~cDNA EST yk198e11.3 comes from this gene~cDNA EST yk247b6.5 comes from this ge> Length = 240 Score = 141 bits (351), Expect = 1e-32 Identities = 83/243 (34%), Positives = 139/243 (57%), Gaps = 5/243 (2%) Query: 8 LKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL 67 + +I E+G RIDGR+ ++R I +G+ +NA GS Y+E G K++ AVYGP E K Sbjct: 1 MNIISEHGFRIDGRRPAQIRNINTRLGLNRNAEGSCYLEHGNTKVLCAVYGPYE--GKSS 58 Query: 68 QR-PDRAILRVRYNMAPFSVEERK-KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDV 125 +R D+ + +Y+ FS ERK + DR+S EIS++++ A E ++ E FPR+ +D+ Sbjct: 59 KRIEDKCAIVCQYSATKFSGLERKNRTRGDRKSTEISRLLEKAFESVILTEAFPRSQLDI 118 Query: 126 FIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEA 185 F EV+Q D A + A SLALADAGIPM+ + +A G ++G+ ++DL E+ Sbjct: 119 FCEVIQGDGSNLAACVNATSLALADAGIPMKGIASAATCGVVDGKPIVDLTSREETDLLP 178 Query: 186 DVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQEV 245 V +A + ++++ L+++ L D + V A K A + + +++LK + Sbjct: 179 RVTLATICGRDEVILVELQNRLHIDH-LSTVMDAAKATCADVYECLAVVAQQHLKACAPI 237 Query: 246 EGS 248 G+ Sbjct: 238 LGN 240 >pir||T11740 hypothetical protein - fission yeast (Schizosaccharomyces pombe) >gi|1749490|dbj|BAA13803.1| (D89141) similar to Saccharomyces cerevisiae hypothetical 27.6KD protein in chromosome VII, SWISS-PROT Accession Number P46948 [Schizosaccharomyces pombe] Length = 242 Score = 126 bits (314), Expect = 2e-28 Identities = 73/230 (31%), Positives = 126/230 (54%), Gaps = 2/230 (0%) Query: 8 LKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL 67 L+++ G R DGR+ E+R + G+ + NGSA+IE G K++ V GP E K Sbjct: 4 LEILSLEGLRNDGRRWDEMRNFQCRFGIEPSENGSAFIELGNTKVLCIVDGPSEPVIKSK 63 Query: 68 QRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKV-IKGALEPALILEMFPRTAIDVF 126 R DR + V N+A FS + KK R I++ + ++ E + E++PR+ I V+ Sbjct: 64 ARADRTFVNVEINIASFSTIDVKKRFKSDRRIQLQCLALQNTFEEIIQTELYPRSQISVY 123 Query: 127 IEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEAD 186 + VLQ D + I A +LAL DAGIP++D V AG +E +++LDLN E++ + Sbjct: 124 LHVLQDDGAVMASCINATTLALIDAGIPVKDFVCCSTAGIVESDMLLDLNSLEES-ALSW 182 Query: 187 VPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKE 236 + VA++ + +Q++ + D + +AI G++ +Y + A+++ Sbjct: 183 LTVAVLGNIKKVVYMQLETSMHLDYLESVMNMAIAGSEHIYNTMQSAVRQ 232 >pir||T11646 tRNA nucleotidyltransferase homolog - fission yeast (Schizosaccharomyces pombe) >gi|2706461|emb|CAA15919.1| (AL021046) putative ribonuclease PH-like [Schizosaccharomyces pombe] Length = 242 Score = 126 bits (314), Expect = 2e-28 Identities = 72/229 (31%), Positives = 126/229 (54%), Gaps = 2/229 (0%) Query: 9 KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQ 68 +++ G R DGR+ E+R + +G+ + NGSA+IE G K++ V GP E K Sbjct: 5 EILSLEGLRNDGRRWDEMRNFQCRIGIEPSENGSAFIELGNTKVLCIVDGPSEPVIKSKA 64 Query: 69 RPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKV-IKGALEPALILEMFPRTAIDVFI 127 R DR + V N+A FS + KK R I++ + ++ E + E++PR+ I V++ Sbjct: 65 RADRTFVNVEINIASFSTIDVKKRFKSDRRIQLQCLALQNTFEEIIQTELYPRSQISVYL 124 Query: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADV 187 VLQ D + I A +LAL DAGIP++D V AG +E +++LDLN E++ + + Sbjct: 125 HVLQDDGAVMASCINATTLALIDAGIPVKDFVCCSTAGIVESDMLLDLNSLEES-ALSWL 183 Query: 188 PVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKE 236 VA++ + +Q++ + D + +AI G++ +Y + A+++ Sbjct: 184 TVAVLGNIKKVVYMQLETSMHLDYLESVMNMAIAGSEHIYNTMQSAVRQ 232 >gi|6321634 homolog of RNAse PH; Ski6p [Saccharomyces cerevisiae] >gi|1176073|sp|P46948|RR41_YEAST RRP41 PROTEIN >gi|2132624|pir||S59180 probable membrane protein YGR195w - yeast (Saccharomyces cerevisiae) >gi|791127|emb|CAA58018.1| (X82775) G7587 [Saccharomyces cerevisiae] >gi|1323347|emb|CAA97221.1| (Z72980) ORF YGR195w [Saccharomyces cerevisiae] Length = 246 Score = 115 bits (285), Expect = 5e-25 Identities = 78/240 (32%), Positives = 124/240 (51%), Gaps = 8/240 (3%) Query: 8 LKLIDENGRRIDGRKKYELRPIKMEVGVLKNA-NGSAYIEWGKNKIIAAVYGPRELHPKH 66 L++ G R+DGR+ ELR + + +A +GS+Y+E G NKII V GP+E K Sbjct: 4 LEIYSPEGLRLDGRRWNELRRFESSINTHPHAADGSSYMEQGNNKIITLVKGPKEPRLKS 63 Query: 67 LQRPDRAILRVRYNMAPFSVEERKKPGP--DRRSIEISKVIKGALEPALILEMFPRTAID 124 +A+L V N+ FS ER K +RR +EI + E ++L ++PRT ID Sbjct: 64 QMDTSKALLNVSVNITKFSKFERSKSSHKNERRVLEIQTSLVRMFEKNVMLNIYPRTVID 123 Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGE 184 + I VL+ D G + I +LAL DAGI M D ++ + G + +LD N E+N Sbjct: 124 IEIHVLEQDGGIMGSLINGITLALIDAGISMFDYISGISVGLYDTTPLLDTNSLEEN-AM 182 Query: 185 ADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQE 244 + V + ++ ++LL ++ + D + + I GA V R+ + E+ K AQ+ Sbjct: 183 STVTLGVVGKSEKLSLLLVEDKIPLDRLENVLAIGIAGAHRV----RDLMDEELRKHAQK 238 >pir||E70320 polyribonucleotide nucleotidyltransferase - Aquifex aeolicus >gi|2982946|gb|AAC06562.1| (AE000679) polyribonucleotide nucleotidyltransferase [Aquifex aeolicus] Length = 775 Score = 99.8 bits (245), Expect = 3e-20 Identities = 84/247 (34%), Positives = 125/247 (50%), Gaps = 34/247 (13%) Query: 13 ENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDR 72 + G RIDGRK E+RPI +EV + +G+A G+ + V L PD Sbjct: 309 KEGVRIDGRKPNEIRPIWIEVHPFERPHGNAIFTRGQTQAYVTVT---------LGTPDE 359 Query: 73 AIL-------------RVRYNMAPFSVEERKKPGPDRR-SIEISKVIKGALEPALILEMF 118 A++ + Y+M PFSV E K GP RR I + + A+EP L E Sbjct: 360 ALIIETIAEGEVFKRFMLHYSMPPFSVGEAKPWGPPRRREIGHGALAERAIEPLLPPEEE 419 Query: 119 PRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRD--LVAACAAGKIEGE----IV 172 I V ++L+++ T +A + ASLAL DAG+PM+D VA A G I + I+ Sbjct: 420 YPFIIRVVSDILESNGSTSMATVCGASLALFDAGVPMKDNKHVAGIAMGLILEKDRYVIL 479 Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229 D+ +ED+ G+ D VA K+ IT +QMD +TK+ ++A+K A +G + +K Sbjct: 480 SDILGDEDHLGDMDFKVA--GTKDGITSVQMDIKVKGITKEIMLDALKQAREGRLYILEK 537 Query: 230 QREALKE 236 EA+ E Sbjct: 538 MYEAIPE 544 >sp|O67069|RNPH_AQUAE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE) >gi|7435289|pir||B70380 tRNA nucleotidyltransferase (EC 2.7.7.56) - Aquifex aeolicus >gi|2983451|gb|AAC07032.1| (AE000714) RNase PH [Aquifex aeolicus] Length = 255 Score = 99.5 bits (244), Expect = 3e-20 Identities = 75/234 (32%), Positives = 120/234 (51%), Gaps = 19/234 (8%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R DGRK+ +LRP+ ++ L+ GS I +GK K+I E P L+ + + Sbjct: 2 RSDGRKEDQLRPVSIQRDFLEYPEGSCLISFGKTKVICTA-SVIENVPNWLKGKGQGWIT 60 Query: 77 VRYNMAPFSVEER--KKPGPDR---RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y+M P + ++R ++ R R+ EI ++I A+ A+ L I V +V+Q Sbjct: 61 AEYSMLPRATQQRTIRESVQGRIGGRTHEIQRMIGRAMRTAVELTKIGERTIWVDCDVIQ 120 Query: 132 ADAGTRVAGITAASLALADAGI-----------PMRDLVAACAAGKIEGEIVLDLNKEED 180 AD GTR A IT A +A+ADA I P++D VAA + G + I+LDLN EED Sbjct: 121 ADGGTRTAAITGAFVAVADAIIKLHKEGIIEETPIKDFVAAVSVGIVNDRILLDLNFEED 180 Query: 181 NYGEADVPV--AIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQRE 232 + + D+ V +++ + + TKDE I+ + LA KG + + Q++ Sbjct: 181 SAAQVDMNVVGTGSGRLSEVHTMGEEYSFTKDELIKMLDLAQKGINELIELQKK 234 >pir||D82978 ribonuclease PH PA5334 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951653|gb|AAG08719.1|AE004946_3 (AE004946) ribonuclease PH [Pseudomonas aeruginosa] Length = 239 Score = 99.1 bits (243), Expect = 4e-20 Identities = 76/241 (31%), Positives = 118/241 (48%), Gaps = 25/241 (10%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R GR +LRPI++ K+A GS +E+G K+I V + P+ L+ + L Sbjct: 3 RPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGV-PRFLKGQGQGWLT 61 Query: 77 VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y M P S ER + R R++EI ++I +L AL L + + +V+Q Sbjct: 62 AEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLRAALDLSKLGENTLYIDCDVIQ 121 Query: 132 ADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEED 180 AD GTR A IT A++AL DA G P++ +VAA + G +G VLDL+ ED Sbjct: 122 ADGGTRTASITGATVALIDALAVLKKRGALKGNPLKQMVAAVSVGIYQGVPVLDLDYLED 181 Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEA-----VKLAIKGAKAVYQKQREALK 235 + E D+ V + +++ G F A ++LA +G + +++ QR AL Sbjct: 182 SAAETDLNVVMTDAGG---FIEVQGTAEGAPFRPAELNAMLELAQQGMQELFELQRAALA 238 Query: 236 E 236 E Sbjct: 239 E 239 >sp|P03842|RNPH_ECOLI RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE) Length = 238 Score = 94.0 bits (230), Expect = 1e-18 Identities = 71/236 (30%), Positives = 111/236 (46%), Gaps = 25/236 (10%) Query: 20 GRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRY 79 GR ++RP+ + K+A GS +E+G K++ E P+ L+ + + Y Sbjct: 5 GRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTA-SIEEGVPRFLKGQGQGWITAEY 63 Query: 80 NMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADA 134 M P S R K R++EI ++I AL A+ L+ I + +VLQAD Sbjct: 64 GMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADG 123 Query: 135 GTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEEDNYG 183 GTR A IT A +AL DA PM+ +VAA + G + GE V DL ED+ Sbjct: 124 GTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAA 183 Query: 184 EADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQKQREAL 234 E D+ V + D ++++ G T +E + + LA G +++ Q+ AL Sbjct: 184 ETDMNVV---MTEDGRIIEVQGTAEGEPFTHEELLILLALARGGIESIVATQKAAL 236 >sp|P50597|RNPH_PSEAE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE) >gi|1079663|gb|AAC44429.1| (U38241) RNase PH [Pseudomonas aeruginosa] Length = 239 Score = 93.6 bits (229), Expect = 2e-18 Identities = 73/241 (30%), Positives = 117/241 (48%), Gaps = 25/241 (10%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R GR +LRPI++ K+A GS +E+G K+I V + P+ L+ + L Sbjct: 3 RPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGV-PRFLKGQGQGWLT 61 Query: 77 VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y M S ER + R R++EI ++I +L AL L + + +V+Q Sbjct: 62 AEYGMLRRSTGERNQREASRGKQGGRTLEIQRLIDRSLRAALDLSKLGENTLYIDCDVIQ 121 Query: 132 ADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEED 180 D GTR A IT A+++L DA G P++ +VAA + G +G VLDL+ ED Sbjct: 122 TDGGTRTASITGATVSLIDALAVLKKRVALKGNPLKQIVAAVSVGIYQGVPVLDLDYLED 181 Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEA-----VKLAIKGAKAVYQKQREALK 235 + E+D+ V + + +++ G F A ++LA +G + + + QR AL Sbjct: 182 SAAESDLNVVMTDCRR---FIEVQGTAEGAPFRPAELNAMLELAQQGMQELVRTQRAALA 238 Query: 236 E 236 E Sbjct: 239 E 239 >sp|P44444|RNPH_HAEIN RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE) >gi|1075223|pir||A64059 tRNA nucleotidyltransferase (EC 2.7.7.56) - Haemophilus influenzae (strain Rd KW20) >gi|1573239|gb|AAC21939.1| (U32713) ribonuclease PH (rph) [Haemophilus influenzae Rd] Length = 238 Score = 93.2 bits (228), Expect = 3e-18 Identities = 70/239 (29%), Positives = 118/239 (49%), Gaps = 25/239 (10%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R + R+ + R IK+ K+A GS +E+G K++ + P+ L+ + + Sbjct: 2 RPNNRENNQPRQIKITRNYTKHAEGSVLVEFGDTKVLCTAT-VEDAVPRFLKGQGQGWVT 60 Query: 77 VRYNMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y M P S R K R++EI ++I +L + L+ AI + +V+Q Sbjct: 61 AEYGMLPRSTHSRMQREAAKGKQGGRTMEIQRLIARSLRAMVDLKALGERAITLDCDVIQ 120 Query: 132 ADAGTRVAGITAASLALADA--GI---------PMRDLVAACAAGKIEGEIVLDLNKEED 180 AD GTR A IT A++AL DA G+ P++ LV+A + G ++G+ V DL ED Sbjct: 121 ADGGTRTASITGAAVALCDAINGLIENGTLKTNPIKGLVSAISVGIVDGQAVCDLEYVED 180 Query: 181 NYGEADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQKQREAL 234 + E D+ V +M D ++++ G + +E + + LA +G ++ QREAL Sbjct: 181 SAAETDMNVVMM---EDGRMIEVQGTAEGEPFSHEELLTLLDLAKQGCNQIFIAQREAL 236 >pir||QQECPE tRNA nucleotidyltransferase (EC 2.7.7.56) - Escherichia coli >gi|499181|emb|CAA25357.1| (X00781) unidentified reading frame (orfE) [Escherichia coli] Length = 238 Score = 92.4 bits (226), Expect = 4e-18 Identities = 71/236 (30%), Positives = 111/236 (46%), Gaps = 25/236 (10%) Query: 20 GRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRY 79 GR ++RP+ + K+A GS +E+G K++ E P+ L+ + + Y Sbjct: 5 GRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTA-SIEEGVPRFLKGQGQGWITAEY 63 Query: 80 NMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADA 134 M P S R K R++EI ++I AL A+ L+ I + +VLQADA Sbjct: 64 GMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADA 123 Query: 135 GTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEEDNYG 183 TR A IT A +AL DA PM+ +VAA + G + GE V DL ED+ Sbjct: 124 WTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAA 183 Query: 184 EADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQKQREAL 234 E D+ V + D ++++ G T +E + + LA G +++ Q+ AL Sbjct: 184 ETDMNVV---MTEDGRIIEVQGTAEGEPFTHEELLILLALARGGIESIVATQKAAL 236 >pir||A72264 polynucleotide phosphorylase - Thermotoga maritima (strain MSB8) >gi|4981905|gb|AAD36416.1|AE001789_1 (AE001789) polynucleotide phosphorylase [Thermotoga maritima] Length = 708 Score = 91.7 bits (224), Expect = 8e-18 Identities = 76/208 (36%), Positives = 107/208 (50%), Gaps = 18/208 (8%) Query: 9 KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQ 68 +LI E G R DGRK E+RPI EVG+ +GSA G+ + + V P +Q Sbjct: 309 RLIVEKGIRADGRKPTEIRPISCEVGLFPRTHGSALFTRGETQSLGIVTLGA---PMDVQ 365 Query: 69 RPDRAI------LRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEM-FPR 120 D + + YN PF E K GP RR I + + AL+ L E FP Sbjct: 366 IIDTLLEEGVKRFMLHYNFPPFCTGEVKPLRGPSRREIGHGHLAERALKNMLPPEEEFPY 425 Query: 121 TAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI---EGEIVL-DLN 176 T I V E+L+++ + +A + + SLAL DAG+P++ VA A G I + EI+L D+ Sbjct: 426 T-IRVVSEILESNGSSSMATVCSGSLALMDAGVPIKKHVAGIAMGLILEEDAEIILTDII 484 Query: 177 KEEDNYGEADVPVAIMPLKNDITLLQMD 204 ED+YG+ D VA ++ IT QMD Sbjct: 485 GMEDHYGDMDFKVA--GTRDGITAFQMD 510 >emb|CAB06341.1| (Z84207) polynucleotide phosphorylase [Thermus thermophilus] Length = 713 Score = 91.3 bits (223), Expect = 1e-17 Identities = 78/220 (35%), Positives = 112/220 (50%), Gaps = 15/220 (6%) Query: 9 KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPK 65 +L+ E G+R DGR +LRPI +EV VL A+GSA G+ +++ V G E Sbjct: 319 RLVLEEGKRADGRGPKDLRPIWIEVDVLPRAHGSAVFTRGETQVLGTVTLGTGRDEQILD 378 Query: 66 HLQRPDRAILRVRYNMAPFSV-EERKKPGPDRRSIEISKVIKGALEPALILEM-FPRTAI 123 L + V YN PFS E R+ G RR + + K AL+ + E FP T I Sbjct: 379 DLGIDETEKFLVHYNFPPFSTGEVRRLRGVSRREVGHGNLAKRALKAVMPKEEDFPYT-I 437 Query: 124 DVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEE 179 V +VL+++ + +A + A LAL DAG+P+R VA A G + E I+ D+ E Sbjct: 438 RVVGDVLESNGSSSMATVCAGCLALMDAGVPIRAPVAGVAMGLVWEENRAVILTDILGLE 497 Query: 180 DNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAV 216 D G+ D VA + +T LQMD G L ++ EA+ Sbjct: 498 DALGDMDFKVA--GTRKGVTALQMDNKVGGLPREVLKEAL 535 >gb|AAF72714.1|AF263927_2 (AF263927) ribonuclease PH [Carnobacterium sp. St2] Length = 364 Score = 90.9 bits (222), Expect = 1e-17 Identities = 77/247 (31%), Positives = 121/247 (48%), Gaps = 24/247 (9%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRELHPKHLQRPDRAIL 75 R + RK ELR + +E LK+ GS + +G K+I A P+ P ++ + + Sbjct: 2 RTNTRKNDELRLVTIETNYLKHPEGSVLVSFGDTKVICNATVEPKV--PPFMRGQGKGWV 59 Query: 76 RVRYNMAPFS-----VEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVL 130 Y M P + + E K R++EI ++I +L + LE AI V +V+ Sbjct: 60 HAEYAMLPRATNTRTIREAAKGKLTGRTMEIQRLIARSLRSVIDLEKLGERAITVDCDVI 119 Query: 131 QADAGTRVAGITAASLA-------LADAG----IPMRDLVAACAAG-KIEGEIVLDLNKE 178 QAD GTR A IT A +A L D+G P+++ +AA + G +GE VLDL+ Sbjct: 120 QADGGTRTASITGAFVALKMAIQTLLDSGQLTEDPVKENIAAVSVGITKQGEAVLDLDYL 179 Query: 179 EDNYGEADVPVAIMPLKNDITLLQMDG---YLTKDEFIEAVKLAIKGAKAVYQKQREALK 235 ED+ D+ + M + LQ G + D+ +E ++L KG ++Q Q +ALK Sbjct: 180 EDSSAAVDMNL-FMTANGEFFELQGTGEEATFSNDQLMEMLELGKKGLNELFQIQTQALK 238 Query: 236 EKYLKIA 242 E +K A Sbjct: 239 ESKVKKA 245 >gb|AAA61996.1| (L10328) RNase PH [Escherichia coli] >gi|1790074|gb|AAC76667.1| (AE000441) RNase PH [Escherichia coli K12] Length = 228 Score = 88.5 bits (216), Expect = 7e-17 Identities = 64/209 (30%), Positives = 98/209 (46%), Gaps = 20/209 (9%) Query: 20 GRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRY 79 GR ++RP+ + K+A GS +E+G K++ E P+ L+ + + Y Sbjct: 5 GRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTA-SIEEGVPRFLKGQGQGWITAEY 63 Query: 80 NMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADA 134 M P S R K R++EI ++I AL A+ L+ I + +VLQAD Sbjct: 64 GMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADG 123 Query: 135 GTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEEDNYG 183 GTR A IT A +AL DA PM+ +VAA + G + GE V DL ED+ Sbjct: 124 GTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAA 183 Query: 184 EADVPVAIMPLKNDITLLQMDGYLTKDEF 212 E D+ V + D ++++ G + F Sbjct: 184 ETDMNVV---MTEDGRIIEVQGTAEGEPF 209 >sp|P28619|RNPH_BACSU RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE) >gi|143444|gb|AAA22705.1| (M85163) RNase PH [Bacillus subtilis] >gi|1770059|emb|CAA99554.1| (Z75208) RNase PH [Bacillus subtilis] >gi|2635302|emb|CAB14797.1| (Z99118) ribonuclease PH [Bacillus subtilis] Length = 245 Score = 87.8 bits (214), Expect = 1e-16 Identities = 77/238 (32%), Positives = 113/238 (47%), Gaps = 22/238 (9%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R DGR+ ELRPI ++ + + GS I G K+I + P L+ + + Sbjct: 2 RHDGRQHDELRPITFDLDFISHPEGSVLITAGNTKVICNA-SVEDRVPPFLRGGGKGWIT 60 Query: 77 VRYNMAPFSVEER-----KKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y+M P + +R K R++EI ++I AL + LE I + +V+Q Sbjct: 61 AEYSMLPRATNQRTIRESSKGKISGRTMEIQRLIGRALRAVVDLEKLGERTIWIDCDVIQ 120 Query: 132 ADAGTRVAGITAASLALA-------DAGI----PMRDLVAACAAG-KIEGEIVLDLNKEE 179 AD GTR A IT A LA+A AG P+ D +AA + G E I+LDLN EE Sbjct: 121 ADGGTRTASITGAFLAMAIAIGKLIKAGTIKTNPITDFLAAISVGIDKEQGILLDLNYEE 180 Query: 180 DNYGEADVPVAIMPLKNDITLLQMDG---YLTKDEFIEAVKLAIKGAKAVYQKQREAL 234 D+ E D+ V IM LQ G ++++ + LA KG + + KQ+E L Sbjct: 181 DSSAEVDMNV-IMTGSGRFVELQGTGEEATFSREDLNGLLGLAEKGIQELIDKQKEVL 237 >sp|Q10628|RNPH_MYCTU PROBABLE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE) >gi|7435288|pir||C70739 probable rphA protein - Mycobacterium tuberculosis (strain H37RV) >gi|1419043|emb|CAA99973.1| (Z75555) rphA [Mycobacterium tuberculosis] Length = 259 Score = 87.8 bits (214), Expect = 1e-16 Identities = 72/245 (29%), Positives = 111/245 (44%), Gaps = 26/245 (10%) Query: 16 RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAIL 75 +R DGR +ELRP+ + G +N GS IE+G K++ E P+ + L Sbjct: 3 KREDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTA-SVTEGVPRWRKATGLGWL 61 Query: 76 RVRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVL 130 Y M P + R R R+ EIS++I +L + L I + +VL Sbjct: 62 TAEYAMLPSATHSRSDRESVRGRLSGRTQEISRLIGRSLRACIDLAALGENTIAIDCDVL 121 Query: 131 QADAGTRVAGITAASLALADAGI------------PMRDLVAACAAGKIEGEIVLDLNKE 178 QAD GTR A IT A +ALADA P+ +AA + G ++G I +DL E Sbjct: 122 QADGGTRTAAITGAYVALADAVTYLSAAGKLSDPRPLSCAIAAVSVGVVDGRIRVDLPYE 181 Query: 179 EDNYGEADVPVAIMPLKNDITLLQMDG-----YLTKDEFIEAVKLAIKGAKAVYQKQREA 233 ED+ E D+ V + TL+++ G + + + +A+ ++ QR+A Sbjct: 182 EDSRAEVDMNVV---ATDTGTLVEIQGTGEGATFARSTLDKLLDMALGACDTLFAAQRDA 238 Query: 234 LKEKY 238 L Y Sbjct: 239 LALPY 243 >sp|O87792|PNP_PSEPU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE PHOSPHORYLASE) (PNPASE) >gi|3650364|emb|CAA77048.1| (Y18132) polyribonucleotide nucleotidyltransferase [Pseudomonas putida] Length = 701 Score = 87.4 bits (213), Expect = 1e-16 Identities = 68/201 (33%), Positives = 109/201 (53%), Gaps = 13/201 (6%) Query: 14 NGR-RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK--IIAAVYGPRELHPKH-LQR 69 NG+ RIDGR +RP+ +EVGVL +GSA G+ + ++A + R+ L+ Sbjct: 312 NGKPRIDGRDNKTVRPLNIEVGVLPKTHGSALFTRGETQALVVATLGTARDAQLLDTLEG 371 Query: 70 PDRAILRVRYNMAPFSVEE-RKKPGPDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFI 127 + + YN PFSV E + G RR I ++ + +++ L ++FP T I V Sbjct: 372 EKKDPFMLHYNFPPFSVGECGRMGGAGRREIGHGRLARRSVQAMLPAADVFPYT-IRVVS 430 Query: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYG 183 E+ +++ + +A + ASLAL DAG+PM+ VA A G + EG+ ++ D+ +ED+ G Sbjct: 431 EITESNGSSSMASVCGASLALMDAGVPMKAPVAGIAMGLVKEGDKFAVLTDILGDEDHLG 490 Query: 184 EADVPVAIMPLKNDITLLQMD 204 + D VA +T LQMD Sbjct: 491 DMDFKVA--GTAKGVTALQMD 509 >pir||C83052 polyribonucleotide nucleotidyltransferase PA4740 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951002|gb|AAG08126.1|AE004888_1 (AE004888) polyribonucleotide nucleotidyltransferase [Pseudomonas aeruginosa] Length = 701 Score = 87.4 bits (213), Expect = 1e-16 Identities = 72/203 (35%), Positives = 110/203 (53%), Gaps = 17/203 (8%) Query: 14 NGR-RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK--IIAAVYGPRE---LHPKHL 67 NG+ RIDGR +RP+++EVGVL +GSA G+ + ++A + R+ L Sbjct: 312 NGKPRIDGRDTRTVRPLRIEVGVLGKTHGSALFTRGETQALVVATLGTARDAQLLDTLEG 371 Query: 68 QRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDV 125 +R D +L YN PFSV E + G P RR I ++ + + L + FP T I V Sbjct: 372 ERKDAFMLH--YNFPPFSVGECGRMGSPGRREIGHGRLARRGVAAMLPTQDEFPYT-IRV 428 Query: 126 FIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDN 181 E+ +++ + +A + ASLAL DAG+P++ VA A G + EGE ++ D+ +ED+ Sbjct: 429 VSEITESNGSSSMASVCGASLALMDAGVPVKAPVAGIAMGLVKEGEKFAVLTDILGDEDH 488 Query: 182 YGEADVPVAIMPLKNDITLLQMD 204 G+ D VA +T LQMD Sbjct: 489 LGDMDFKVA--GTDKGVTALQMD 509 >dbj|BAB06787.1| (AP001517) ribonuclease PH [Bacillus halodurans] Length = 257 Score = 87.0 bits (212), Expect = 2e-16 Identities = 74/239 (30%), Positives = 116/239 (47%), Gaps = 24/239 (10%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R+D RK ELRPI +E+ L + GS I G K+I + P L+ + + Sbjct: 2 RMDERKADELRPISIEINYLHHPEGSVLISIGNTKVICTA-SLEDRVPPFLRGQGKGWIT 60 Query: 77 VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y+M P + E+R R R++EI ++I AL + L+ + + +V+Q Sbjct: 61 AEYSMLPRATEQRNMRESTRGKVSGRTMEIQRLIGRALRSIIDLDKIGERTVWIDCDVIQ 120 Query: 132 ADAGTRVAGITAASL--------ALADAGI---PMRDLVAACAAGKIEGEI--VLDLNKE 178 AD GTR IT A + ALA+ I P+ D +AA + G I+ ++ +LDL Sbjct: 121 ADGGTRTTSITGAFVALSLAMEKALANGAIQEWPIDDFLAAVSVG-IDPKLGAILDLCYA 179 Query: 179 EDNYGEADVPVAIMPLKNDITLLQMDG---YLTKDEFIEAVKLAIKGAKAVYQKQREAL 234 ED E D+ V +M K + LQ G + ++ + + LA KG K + ++QR AL Sbjct: 180 EDAQAEVDMNV-VMTGKGEYVELQGTGEEATFSHNQLLTILALADKGIKQLIEEQRNAL 237 >pir||A44914 tRNA nucleotidyltransferase (EC 2.7.7.56) - Bacillus subtilis Length = 245 Score = 86.6 bits (211), Expect = 3e-16 Identities = 77/238 (32%), Positives = 112/238 (46%), Gaps = 22/238 (9%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R DGR ELRPI ++ + + GS I G K+I + P L+ + + Sbjct: 2 RHDGRGHDELRPITFDLDFISHPEGSVLITAGNTKVICNA-SVEDRVPPFLRGGGKGWIT 60 Query: 77 VRYNMAPFS-----VEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y+M P + + E K R++EI ++I AL + LE I + +V+Q Sbjct: 61 AEYSMLPRATNGRTIRESSKGKISGRTMEIQRLIGRALRAVVDLEKLGERTIWIDCDVIQ 120 Query: 132 ADAGTRVAGITAASLALA-------DAGI----PMRDLVAACAAG-KIEGEIVLDLNKEE 179 AD GTR A IT A LA+A AG P+ D +AA + G E I+LDLN EE Sbjct: 121 ADGGTRTASITGAFLAMAIAIGKLIKAGTIKTNPITDFLAAISVGIDKEQGILLDLNYEE 180 Query: 180 DNYGEADVPVAIMPLKNDITLLQMDG---YLTKDEFIEAVKLAIKGAKAVYQKQREAL 234 D+ E D+ V IM LQ G ++++ + LA KG + + KQ+E L Sbjct: 181 DSSAEVDMNV-IMTGSGRFVELQGTGEEATFSREDLNGLLGLAEKGIQELIDKQKEVL 237 >pir||G81332 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) Cj1253 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968686|emb|CAB73507.1| (AL139077) polyribonucleotide nucleotidyltransferase [Campylobacter jejuni] Length = 719 Score = 85.8 bits (209), Expect = 4e-16 Identities = 78/245 (31%), Positives = 119/245 (47%), Gaps = 21/245 (8%) Query: 9 KLIDEN----GRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK--IIAAVYGPREL 62 KLI E G+R DGR E+RPI +E +L NA+GS G+ + ++A + G + Sbjct: 324 KLIREQILNEGKRADGRSLNEVRPISIETNILPNAHGSCLFTRGQTQALVVATLGGENDS 383 Query: 63 HPKHL---QRPDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEMF 118 L + P V YN FSV E P RR + + K AL P+ + E + Sbjct: 384 QMIDLLTEKNPISERFMVNYNFPGFSVGEASPIKAPGRRELGHGNLAKRALYPS-VDENY 442 Query: 119 PRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI----EGEIVLD 174 P I + E+L+++ + +A + SLAL AG+P LVA A G I + ++ D Sbjct: 443 P-YVIRLVSEILESNGSSSMATVCGGSLALKAAGVPSLKLVAGVAMGLIFEDNKYAVLTD 501 Query: 175 LNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQKQR 231 + ED+ G+ D VA K+ +T LQMD G + ++ +A+ A +G + Sbjct: 502 IMGLEDHDGDMDFKVA--GSKDGVTALQMDIKLGGIDQEILKQALYQAKEGRIHILNIME 559 Query: 232 EALKE 236 EA KE Sbjct: 560 EAAKE 564 >sp|P37939|RNPH_MYCLE PROBABLE RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE) >gi|2145985|pir||S72788 tRNA nucleotidyltransferase (EC 2.7.7.56) - Mycobacterium leprae >gi|466905|gb|AAA50880.1| (U00014) rnpH; ribonuclease PH; B1549_C1_182 [Mycobacterium leprae] Length = 259 Score = 85.4 bits (208), Expect = 6e-16 Identities = 72/250 (28%), Positives = 114/250 (44%), Gaps = 26/250 (10%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R DGR ELR + + G ++ GS IE+G K++ P E P+ + + L Sbjct: 4 RADGRLDDELRAVVITRGFTEHPAGSVLIEFGHTKVMCTA-SPTEGVPRWRKGSGKGWLT 62 Query: 77 VRYNMAPFSVEERK-----KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y M P + R K R+ EIS++I +L + L I V +VLQ Sbjct: 63 AEYAMLPSATHTRSERESVKGRLSGRTQEISRLIGRSLRACIDLAALGENTIAVDCDVLQ 122 Query: 132 ADAGTRVAGITAASLALADAGI------------PMRDLVAACAAGKIEGEIVLDLNKEE 179 AD GTR A +T A +ALADA P+ +AA + G ++G I +DL+ EE Sbjct: 123 ADGGTRTAAVTGAYVALADAVTYLSAAGRLLDPRPLSCAIAAVSVGVVDGRIRVDLSYEE 182 Query: 180 DNYGEADVPVAIMPLKNDITLLQMDG-----YLTKDEFIEAVKLAIKGAKAVYQKQREAL 234 D+ E D+ V + TL+++ G + + + +A+ ++ QR+AL Sbjct: 183 DSRAEVDMNVI---ATDTGTLVEIQGTGEGATFPRSTLDKLLDMALGACDKLFVAQRDAL 239 Query: 235 KEKYLKIAQE 244 Y ++ E Sbjct: 240 ALPYQGMSPE 249 >sp|P50849|PNPA_BACSU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE PHOSPHORYLASE) (PNPASE) (VEGETATIVE PROTEIN 15) (VEG15) >gi|2127172|pir||S70691 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain pnpA - Bacillus subtilis >gi|1184680|gb|AAC43595.1| (U29668) polynucleotide phosphorylase [Bacillus subtilis] >gi|2634041|emb|CAB13542.1| (Z99112) polynucleotide phosphorylase (PNPase) [Bacillus subtilis] >gi|1589234|prf||2210369A polynucleotide phosphorylase [Bacillus subtilis] Length = 705 Score = 84.7 bits (206), Expect = 1e-15 Identities = 79/254 (31%), Positives = 126/254 (49%), Gaps = 19/254 (7%) Query: 4 KPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-----AVYG 58 K E +LI E R DGR ++RP+ EVG+L +GS G+ + ++ A+ Sbjct: 303 KNEVRRLITEEKVRPDGRGVDQIRPLSSEVGLLPRTHGSGLFTRGQTQALSVCTLGALGD 362 Query: 59 PRELHPKHLQRPDRAILRVRYNMAPFSVEER-KKPGPDRRSIEISKVIKGALEPALILEM 117 + L ++ R + YN FSV E GP RR I + + ALEP + E Sbjct: 363 VQILDGLGVEESKRFMHH--YNFPQFSVGETGPMRGPGRREIGHGALGERALEPVIPSEK 420 Query: 118 -FPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIE-GE---IV 172 FP T + + EVL+++ T A I A++LA+ DAG+P++ VA A G ++ GE ++ Sbjct: 421 DFPYT-VRLVSEVLESNGSTSQASICASTLAMMDAGVPIKAPVAGIAMGLVKSGEHYTVL 479 Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229 D+ ED G+ D VA + +T LQMD L+++ EA++ A KG + Sbjct: 480 TDIQGMEDALGDMDFKVA--GTEKGVTALQMDIKIEGLSREILEEALQQAKKGRMEILNS 537 Query: 230 QREALKEKYLKIAQ 243 L E ++++ Sbjct: 538 MLATLSESRKELSR 551 >sp|P57454|PNP_BUCAI POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE PHOSPHORYLASE) (PNPASE) >gi|10039043|dbj|BAB13077.1| (AP001119) polyribonucleotide nucleotidyltransferase [Buchnera sp. APS] Length = 707 Score = 84.7 bits (206), Expect = 1e-15 Identities = 71/214 (33%), Positives = 109/214 (50%), Gaps = 16/214 (7%) Query: 2 MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRE 61 +EK K I N RIDGR+K +R + + G+L +GSA G+ + + +V Sbjct: 300 IEKKVVRKRILSNQTRIDGREKDMIRALDVRTGILPRTHGSALFTRGETQSLVSVTLGTS 359 Query: 62 LHPKHLQ-----RPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-I 114 ++L R D + YN P+SV E G P RR I ++ K +L + Sbjct: 360 RDAQNLDELLGDRIDNFLFH--YNFPPYSVGEIGMVGSPKRREIGHGRLAKRSLLAVMPT 417 Query: 115 LEMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE--- 170 LE FP T I V E+ +++ + +A + ASLAL DAG+P++ VA + G + EG Sbjct: 418 LENFPYT-IRVVSEITESNGSSSMASVCGASLALMDAGVPIKSAVAGISMGLVKEGNQHV 476 Query: 171 IVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMD 204 ++ D+ +ED+ G+ D VA + IT LQMD Sbjct: 477 LLSDILGDEDHLGDMDFKVA--GTEEGITALQMD 508 >dbj|BAB06126.1| (AP001515) polynucleotide phosphorylase [Bacillus halodurans] Length = 704 Score = 84.3 bits (205), Expect = 1e-15 Identities = 76/247 (30%), Positives = 121/247 (48%), Gaps = 19/247 (7%) Query: 4 KPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-----AVYG 58 K E +LI R DGR+ E+RP+ +VG+L +GS G+ + ++ A+ Sbjct: 301 KEEVRRLITVEKIRPDGREIDEIRPLSSQVGILPRTHGSGLFTRGQTQALSICTLGALGD 360 Query: 59 PRELHPKHLQRPDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEM 117 + L ++ R + YN FSV E GP RR I + + ALEP + E Sbjct: 361 VQILDGLGIEESKRFMHH--YNFPQFSVGETGPIRGPGRREIGHGALGERALEPVIPSEQ 418 Query: 118 -FPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IV 172 FP T I + EVL+++ T A I A++LA+ DAG+P++ VA A G ++ + ++ Sbjct: 419 DFPYT-IRLVSEVLESNGSTSQASICASTLAMMDAGVPIKAPVAGIAMGLVKQDEHVSVL 477 Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229 D+ ED G+ D VA + +T LQMD + + +A++ A KG + Sbjct: 478 TDIQGMEDALGDMDFKVA--GTRKGVTALQMDIKISGIDRAILEQALEQARKGRMIILDN 535 Query: 230 QREALKE 236 EA+ E Sbjct: 536 MLEAISE 542 >pir||S74509 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain - Synechocystis sp. (strain PCC 6803) >gi|1651733|dbj|BAA16661.1| (D90899) polyribonucleotide nucleotidyltransferase [Synechocystis sp.] Length = 718 Score = 82.7 bits (201), Expect = 4e-15 Identities = 78/247 (31%), Positives = 120/247 (48%), Gaps = 27/247 (10%) Query: 9 KLIDENGRRIDGRKKYELRPIKMEVGVL-KNANGSAYIEWGKNKIIA-AVYGPR------ 60 K I ++G R+DGRK ++RPI EVG L + +GS G ++++ A G Sbjct: 316 KQIVDDGVRVDGRKLEQVRPISCEVGFLPRRVHGSGLFNRGLTQVLSLATLGSPGDAQDL 375 Query: 61 --ELHPKHLQRPDRAILRVRYNMAPFSV-EERKKPGPDRRSIEISKVIKGALEPALI-LE 116 +LHP+ +R YN P+SV E R P RR I + + A+ P L E Sbjct: 376 ADDLHPEDEKR-----YLHHYNFPPYSVGEARPMRSPGRREIGHGALAERAIIPVLPPQE 430 Query: 117 MFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IV 172 FP + V EVL ++ T + + ++LAL DAG+P++ V+ A G I EG+ I+ Sbjct: 431 DFPYV-VRVVSEVLSSNGSTSMGSVCGSTLALMDAGVPIKKPVSGAAMGLIKEGDEIRIL 489 Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229 D+ ED G+ D VA + IT LQMD L+ + +A+ A+ + K Sbjct: 490 TDIQGIEDFLGDMDFKVA--GTDSGITALQMDMKIDGLSMEVVSKAIMQALPARLHILDK 547 Query: 230 QREALKE 236 ++E Sbjct: 548 MLATIRE 554 >pir||T36127 probable ribonuclease PH - Streptomyces coelicolor >gi|5531353|emb|CAB50985.1| (AL096852) putative ribonuclease PH [Streptomyces coelicolor A3(2)] Length = 245 Score = 82.7 bits (201), Expect = 4e-15 Identities = 71/245 (28%), Positives = 109/245 (43%), Gaps = 35/245 (14%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 RIDGR +LRP+ +E G K+A GS + +G K++ E P+ + + Sbjct: 3 RIDGRTPQQLRPVTIERGWSKHAEGSVLVSFGDTKVLCNA-SVTEGVPRWRKGSGEGWVT 61 Query: 77 VRYNMAPFSVEERKKPGPDRRSI---------EISKVIKGALEPALILEMFPRTAIDVFI 127 Y M P + R DR S+ EIS++I +L + + + + Sbjct: 62 AEYAMLPRATNTRG----DRESVKGRIGGRTHEISRLIGRSLRAVIDYKALGENTVVLDC 117 Query: 128 EVLQADAGTRVAGITAASLALADAGI-------------PMRDLVAACAAGKIEGEIVLD 174 +VLQAD GTR A IT A +ALADA P+ V+A + G ++G +LD Sbjct: 118 DVLQADGGTRTAAITGAYVALADAVAWAQGRKLIKANRKPLTGTVSAVSVGIVDGTPLLD 177 Query: 175 LNKEEDNYGEADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQK 229 L EED + D+ V D +++ G +DE + LA G + + Sbjct: 178 LRYEEDVRADTDMNVV---CTGDGRFVEVQGTAEAEPFARDELNTLLDLATAGCTELAEL 234 Query: 230 QREAL 234 QR+AL Sbjct: 235 QRKAL 239 >pir||D70200 polyribonucleotide nucleotidyltransferase (pnpA) homolog - Lyme disease spirochete >gi|2688743|gb|AAC67149.1| (AE001179) polyribonucleotide nucleotidyltransferase (pnpA) [Borrelia burgdorferi] Length = 722 Score = 81.1 bits (197), Expect = 1e-14 Identities = 72/214 (33%), Positives = 108/214 (49%), Gaps = 14/214 (6%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPD---RA 73 R DGR E+R I EV +L +GSA G+ + +A + + + D R Sbjct: 316 RTDGRTPNEIRDIISEVDILSRTHGSALFTRGETQALAVTTLGTSIDEQIMDDIDGDKRL 375 Query: 74 ILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEM-FPRTAIDVFIEVLQA 132 + YN PFSV E + RR I + + ALE + + FP T I V EVL++ Sbjct: 376 NFMLHYNFPPFSVGETGRLMTGRREIGHGHLAQRALESMVPGKNDFPYT-IRVVSEVLES 434 Query: 133 DAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEADVP 188 + + +A + A S++L AG+P++ VA A G I EG+ ++ D+ EED+ G+ D Sbjct: 435 NGSSSMATVCAGSMSLMSAGVPVKGQVAGIAMGLISEGDKYVVLSDILGEEDHLGDMDFK 494 Query: 189 VAIMPLKNDITLLQMD---GYLTKDEFIEAVKLA 219 VA KN IT QMD +TKD +A++ A Sbjct: 495 VA--GTKNGITGFQMDIKIENVTKDLMRDALEQA 526 >pir||D82350 ribonuclease PH VC0210 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9654617|gb|AAF93386.1| (AE004111) ribonuclease PH [Vibrio cholerae] Length = 257 Score = 81.1 bits (197), Expect = 1e-14 Identities = 65/239 (27%), Positives = 111/239 (46%), Gaps = 25/239 (10%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R D R ++RPIK+ A GS +E+G K++ E P+ L+ + + Sbjct: 21 RPDNRAADQVRPIKITRHYTAYAEGSVLVEFGNTKVLCNA-SIEEGVPRWLKGQGKGWVT 79 Query: 77 VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y M P + R + R++EI ++I +L + LE I V +V+Q Sbjct: 80 AEYGMLPRATHSRTRREATNGKQGGRTMEIQRLIARSLRAVVDLEAMGEIMITVDCDVIQ 139 Query: 132 ADAGTRVAGITAASLALADAGI-----------PMRDLVAACAAGKIEGEIVLDLNKEED 180 AD GTR A IT AS+ALADA PM+ VAA + G + +++ DL ED Sbjct: 140 ADGGTRTASITGASVALADAFAHLIAKGQLKKNPMKGHVAAVSVGILGEDVLCDLEYVED 199 Query: 181 NYGEADVPVAIMPLKNDITLLQMDGY-----LTKDEFIEAVKLAIKGAKAVYQKQREAL 234 + + D+ V + + ++++ G + ++ +E + +A KG + Q+ +L Sbjct: 200 SAADTDMNVV---MTEEGKMIEIQGTAEGEPFSHEQLLELLAVAKKGIADIVAVQKASL 255 >pir||H65106 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain - Escherichia coli Length = 734 Score = 80.8 bits (196), Expect = 1e-14 Identities = 72/224 (32%), Positives = 115/224 (51%), Gaps = 20/224 (8%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPRE----LHPKHLQRPD 71 RIDGR+K +R + + GVL +GSA G+ + ++ A G L +R D Sbjct: 338 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTD 397 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129 + YN P+SV E G P RR I ++ K G L ++ FP T + V E+ Sbjct: 398 TFLFH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYT-VRVVSEI 454 Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185 +++ + +A + ASLAL DAG+P++ VA A G + EG+ ++ D+ +ED+ G+ Sbjct: 455 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDM 514 Query: 186 DVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAV 226 D VA ++ I+ LQMD +TK E ++ KGA+ + Sbjct: 515 DFKVA--GSRDGISALQMDIKIEGITK-EIMQVALNQAKGARLI 555 >gb|AAA57967.1| (U18997) polynucleotide phosphorylase [Escherichia coli] >gi|1789555|gb|AAC76198.1| (AE000397) polynucleotide phosphorylase; cytidylate kinase activity [Escherichia coli K12] Length = 734 Score = 80.4 bits (195), Expect = 2e-14 Identities = 66/199 (33%), Positives = 104/199 (52%), Gaps = 16/199 (8%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPRE----LHPKHLQRPD 71 RIDGR+K +R + + GVL +GSA G+ + ++ A G L +R D Sbjct: 338 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTD 397 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129 + YN P+SV E G P RR I ++ K G L ++ FP T + V E+ Sbjct: 398 TFLFH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYT-VRVVSEI 454 Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185 +++ + +A + ASLAL DAG+P++ VA A G + EG+ ++ D+ +ED+ G+ Sbjct: 455 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDM 514 Query: 186 DVPVAIMPLKNDITLLQMD 204 D VA ++ I+ LQMD Sbjct: 515 DFKVA--GSRDGISALQMD 531 >sp|P05055|PNP_ECOLI POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE PHOSPHORYLASE) (PNPASE) Length = 711 Score = 80.4 bits (195), Expect = 2e-14 Identities = 66/199 (33%), Positives = 104/199 (52%), Gaps = 16/199 (8%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPRE----LHPKHLQRPD 71 RIDGR+K +R + + GVL +GSA G+ + ++ A G L +R D Sbjct: 315 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTD 374 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129 + YN P+SV E G P RR I ++ K G L ++ FP T + V E+ Sbjct: 375 TFLFH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYT-VRVVSEI 431 Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185 +++ + +A + ASLAL DAG+P++ VA A G + EG+ ++ D+ +ED+ G+ Sbjct: 432 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDM 491 Query: 186 DVPVAIMPLKNDITLLQMD 204 D VA ++ I+ LQMD Sbjct: 492 DFKVA--GSRDGISALQMD 508 >emb|CAA71697.1| (Y10692) pnp [Yersinia enterocolitica] Length = 711 Score = 80.4 bits (195), Expect = 2e-14 Identities = 65/199 (32%), Positives = 103/199 (51%), Gaps = 16/199 (8%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGP----RELHPKHLQRPD 71 RIDGR+K +R + + GVL +GSA G+ + ++ A G + + +R D Sbjct: 320 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQNIDELMGERTD 379 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129 +L YN P+SV E G P RR I ++ K G L FP T + V E+ Sbjct: 380 SFLLH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPSPSEFPYT-VRVVSEI 436 Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEEDNYGEA 185 +++ + +A + ASLAL DAG+P++ VA A G ++ + ++ D+ +ED+ G+ Sbjct: 437 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEDENFVVLSDILGDEDHLGDM 496 Query: 186 DVPVAIMPLKNDITLLQMD 204 D VA ++ IT LQMD Sbjct: 497 DFKVA--GSRDGITALQMD 513 >sp|O34275|PNP_YEREN POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE PHOSPHORYLASE) (PNPASE) Length = 706 Score = 80.4 bits (195), Expect = 2e-14 Identities = 65/199 (32%), Positives = 103/199 (51%), Gaps = 16/199 (8%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGP----RELHPKHLQRPD 71 RIDGR+K +R + + GVL +GSA G+ + ++ A G + + +R D Sbjct: 315 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQNIDELMGERTD 374 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129 +L YN P+SV E G P RR I ++ K G L FP T + V E+ Sbjct: 375 SFLLH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPSPSEFPYT-VRVVSEI 431 Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEEDNYGEA 185 +++ + +A + ASLAL DAG+P++ VA A G ++ + ++ D+ +ED+ G+ Sbjct: 432 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEDENFVVLSDILGDEDHLGDM 491 Query: 186 DVPVAIMPLKNDITLLQMD 204 D VA ++ IT LQMD Sbjct: 492 DFKVA--GSRDGITALQMD 508 >gi|9910360 exosome component Rrp46 [Homo sapiens] >gi|11424056|ref|XP_008911.1| exosome component Rrp46 [Homo sapiens] >gi|8927592|gb|AAF82135.1|AF281134_1 (AF281134) exosome component Rrp46 [Homo sapiens] Length = 235 Score = 80.0 bits (194), Expect = 2e-14 Identities = 64/221 (28%), Positives = 110/221 (48%), Gaps = 20/221 (9%) Query: 26 LRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFS 85 LR E +L +GSA G ++A VYGP E+ + + +N A Sbjct: 28 LRHFACEQNLLSRPDGSASFLQGDTSVLAGVYGPAEVK----------VSKEIFNKATLE 77 Query: 86 VEERKK---PGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGTRVAG-I 141 V R K PG +S E ++I+ E ++ + PRT+I V ++V+ +DAG+ +A + Sbjct: 78 VILRPKIGLPGVAEKSRE--RLIRNTCEAVVLGTLHPRTSITVVLQVV-SDAGSLLACCL 134 Query: 142 TAASLALADAGIPMRDLV--AACAAGKIEGEIVLDLNKEEDNYGEADVPVAIMPLKNDIT 199 AA +AL DAG+PMR L ACA +G +VLD +++ A + A+ ++ + Sbjct: 135 NAACMALVDAGVPMRALFCGVACALDS-DGTLVLDPTSKQEKEARAVLTFALDSVERKLL 193 Query: 200 LLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLK 240 + G + E + + A ++ V++ RE+L+ +Y K Sbjct: 194 MSSTKGLYSDTELQQCLAAAQAASQHVFRFYRESLQRRYSK 234 >sp|Q9ZD43|PNP_RICPR POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE PHOSPHORYLASE) (PNPASE) >gi|7447101|pir||B71654 polyribonucleotide nucleotidyltransferase (pnp) RP504 - Rickettsia prowazekii >gi|3861056|emb|CAA14956.1| (AJ235272) POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (pnp) [Rickettsia prowazekii] Length = 745 Score = 79.6 bits (193), Expect = 3e-14 Identities = 64/224 (28%), Positives = 118/224 (52%), Gaps = 12/224 (5%) Query: 9 KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPR--ELHPK 65 K++++N RIDGR ++R I EVG+L +A+GSA G+ + +++ +G E Sbjct: 309 KILEKN-IRIDGRSTTDIRQIACEVGLLPSAHGSALFTRGETQSLVSTTFGTSLDEQIVD 367 Query: 66 HLQRPDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPALILEMFPRTAID 124 L+ + + Y P+SV E P RR + K+ A+ P L ++ +I Sbjct: 368 SLEGEYKERFMLNYIFPPYSVNEAMPMKAPSRREVGHGKLAWRAINPILPNKVQFPYSIR 427 Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEED 180 V E +++ + +A + +SLAL AG+P++ VA A G ++ ++ D+ +ED Sbjct: 428 VVAETTESNGSSSMATVCGSSLALMHAGVPIKAPVAGIAMGLVKESNKFAVLSDIIGDED 487 Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAK 224 +G+ D VA + IT LQMD ++ +F + +++A++ A+ Sbjct: 488 YFGDMDFKVA--GTSSGITALQMDIKISGIDF-KIIQIALEQAR 528 >pir||A81866 tRNA nucleotidyltransferase (EC 2.7.7.56) - Neisseria meningitidis (group A strain Z2491) >gi|7380343|emb|CAB84930.1| (AL162756) ribonuclease PH [Neisseria meningitidis Z2491] Length = 242 Score = 79.6 bits (193), Expect = 3e-14 Identities = 71/228 (31%), Positives = 107/228 (46%), Gaps = 21/228 (9%) Query: 26 LRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFS 85 LR IK+ L + +GS IE G K+I + P L+ ++ + Y M P S Sbjct: 14 LRDIKITPHFLPHTDGSCLIECGNTKVICTASIDENV-PPFLRGKNQGWVTAEYGMLPAS 72 Query: 86 VEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGTRVAG 140 R + R+ EI ++I +L + +E I + +V+QAD GTR A Sbjct: 73 TASRMRREASAGKQSGRTQEIQRLIGRSLRAVVDMEKLGERQILIDCDVIQADGGTRTAS 132 Query: 141 ITAASLALADA-------GI----PMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADVPV 189 IT A +AL A GI P+R+ VAA + G + G +LDL+ ED+ ++DV + Sbjct: 133 ITGAFVALQIAVGKLVSDGILSENPIREAVAAVSVGVVNGVPLLDLDYPEDSGCDSDVNI 192 Query: 190 AIMPLKNDITLLQ---MDGYLTKDEFIEAVKLAIKGAKAVYQKQREAL 234 +M I +Q D + DE + V LA KG + Q Q+ AL Sbjct: 193 -VMTASGKIIEIQGTAEDAPFSLDELGKLVALAQKGIGELLQHQQNAL 239 >sp|P41121|PNP_PHOLU POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE PHOSPHORYLASE) (PNPASE) (CAP87K) >gi|7447092|pir||S38883 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) - Xenorhabdus luminescens >gi|561531|emb|CAA53671.1| (X76069) polynucleotide phosphorylase [Photorhabdus luminescens] Length = 709 Score = 79.2 bits (192), Expect = 4e-14 Identities = 67/199 (33%), Positives = 102/199 (50%), Gaps = 16/199 (8%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPRE----LHPKHLQRPD 71 RIDGR+K +R + + GVL +GSA G+ + ++ A G + +R D Sbjct: 315 RIDGREKDMVRALDVRTGVLPRTHGSALFTRGETQALVTATLGTERDAQIIDELMGERTD 374 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129 R +L YN P+SV E G P RR I ++ K G L FP T + V E+ Sbjct: 375 RFLLH--YNFPPYSVGETGMMGSPKRREIGHGRLAKRGVLAVMPKANEFPYT-VRVVSEI 431 Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185 +++ + +A + ASLAL DAG+P++ VA A G + EG+ ++ D+ +ED+ G+ Sbjct: 432 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNFVVLSDILGDEDHLGDM 491 Query: 186 DVPVAIMPLKNDITLLQMD 204 D VA I+ LQMD Sbjct: 492 DFKVA--GSCEGISALQMD 508 >pir||G81076 ribonuclease PH NMB1499 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226741|gb|AAF41855.1| (AE002499) ribonuclease PH [Neisseria meningitidis MC58] Length = 242 Score = 79.2 bits (192), Expect = 4e-14 Identities = 73/231 (31%), Positives = 109/231 (46%), Gaps = 27/231 (11%) Query: 26 LRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFS 85 LR IK+ L + +GS IE G K+I + P L+ ++ + Y M P S Sbjct: 14 LRDIKITPHFLPHTDGSCLIECGNTKVICTASIDENV-PPFLRGKNQGWVTAEYGMLPAS 72 Query: 86 VEER--------KKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGTR 137 R K+ G R+ EI ++I +L + +E I + +V+QAD GTR Sbjct: 73 TASRMLREASAGKQSG---RTQEIQRLIGRSLRAVVDMEKLGERQILIDCDVIQADGGTR 129 Query: 138 VAGITAASLALADA-------GI----PMRDLVAACAAGKIEGEIVLDLNKEEDNYGEAD 186 A IT A +AL A GI P+R+ VAA + G + G +LDL+ ED+ ++D Sbjct: 130 TASITGAFVALQIAVGKLVSDGILSENPIREAVAAVSVGVVNGVPLLDLDYPEDSGCDSD 189 Query: 187 VPVAIMPLKNDITLLQ---MDGYLTKDEFIEAVKLAIKGAKAVYQKQREAL 234 V + +M I +Q D + DE + V LA KG + Q Q+ AL Sbjct: 190 VNI-VMTASGKIIEIQGTAEDAPFSLDELGKLVALAQKGIGELLQHQQNAL 239 >pir||T49262 hypothetical protein F12M12.180 - Arabidopsis thaliana >gi|7799009|emb|CAB90948.1| (AL355775) putative protein [Arabidopsis thaliana] Length = 239 Score = 79.2 bits (192), Expect = 4e-14 Identities = 54/165 (32%), Positives = 80/165 (47%), Gaps = 10/165 (6%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R DGR +LRP+ +L +GSA G K++AAVYGP+ K+ + ++A Sbjct: 5 REDGRTPNQLRPLACSRNILHRPHGSASWSQGDTKVLAAVYGPKAGTKKN-ENAEKACFE 63 Query: 77 VRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGT 136 V + + + +K E ++K ++ +L + P T V I+V+ D Sbjct: 64 VIWKPKSGQIGKVEK--------EYEMILKRTIQSICVLTVNPNTTTSVIIQVVHDDGSL 115 Query: 137 RVAGITAASLALADAGIPMRDL-VAACAAGKIEGEIVLDLNKEED 180 I AA AL DAGIPM+ L VA C G +VLD NK E+ Sbjct: 116 LPCAINAACAALVDAGIPMKHLAVAICCCLAENGYLVLDPNKLEE 160 >prf||2208281A 100RNP protein [Spinacia oleracea] Length = 779 Score = 78.8 bits (191), Expect = 6e-14 Identities = 75/245 (30%), Positives = 118/245 (47%), Gaps = 22/245 (8%) Query: 9 KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK-- 65 K I E GRR DGR +RPI G+L A+GSA G+ + +A V G +++ + Sbjct: 427 KRIVEGGRRSDGRTSEGVRPINSRCGLLPRAHGSALFTRGETQALAVVTLGDKQMAQRID 486 Query: 66 HLQRPDRA-ILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILE-MFPRTA 122 L+ D + ++Y+ P V E + G P RR I + + ALEP L E FP T Sbjct: 487 TLEGDDESKRFYLQYSFPPSCVGEAGRVGAPSRREIGHGTLAERALEPILPSEDEFPYT- 545 Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IV 172 + V + +++ + +A + SLAL DAG+P++ +A A G + +G I+ Sbjct: 546 VRVESNITESNGSSSMASVCGGSLALLDAGVPVKCPIAGIAMGMVLDTKEFGGDGTPLIL 605 Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229 D+ ED G+ D VA + +T QMD G +T +A+ A G K + + Sbjct: 606 SDITGSEDASGDMDFKVA--GNADCVTAFQMDIKVGGITLSVMKQALLQAKDGRKIILAE 663 Query: 230 QREAL 234 + L Sbjct: 664 MSKCL 668 >gb|AAC49669.1| (U52048) polyribonucleotide phophorylase [Spinacia oleracea] Length = 822 Score = 78.8 bits (191), Expect = 6e-14 Identities = 75/245 (30%), Positives = 118/245 (47%), Gaps = 22/245 (8%) Query: 9 KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK-- 65 K I E GRR DGR +RPI G+L A+GSA G+ + +A V G +++ + Sbjct: 429 KRIVEGGRRSDGRTSEGVRPINSRCGLLPRAHGSALFTRGETQALAVVTLGDKQMAQRID 488 Query: 66 HLQRPDRA-ILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILE-MFPRTA 122 L+ D + ++Y+ P V E + G P RR I + + ALEP L E FP T Sbjct: 489 TLEGDDESKRFYLQYSFPPSCVGEAGRVGAPSRREIGHGTLAERALEPILPSEDEFPYT- 547 Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IV 172 + V + +++ + +A + SLAL DAG+P++ +A A G + +G I+ Sbjct: 548 VRVESNITESNGSSSMASVCGGSLALLDAGVPVKCPIAGIAMGMVLDTKEFGGDGTPLIL 607 Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229 D+ ED G+ D VA + +T QMD G +T +A+ A G K + + Sbjct: 608 SDITGSEDASGDMDFKVA--GNADCVTAFQMDIKVGGITLSVMKQALLQAKDGRKIILAE 665 Query: 230 QREAL 234 + L Sbjct: 666 MSKCL 670 >pir||S64680 exoribonuclease 100 RNP - spinach Length = 779 Score = 78.8 bits (191), Expect = 6e-14 Identities = 75/245 (30%), Positives = 118/245 (47%), Gaps = 22/245 (8%) Query: 9 KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK-- 65 K I E GRR DGR +RPI G+L A+GSA G+ + +A V G +++ + Sbjct: 427 KRIVEGGRRSDGRTSEGVRPINSRCGLLPRAHGSALFTRGETQALAVVTLGDKQMAQRID 486 Query: 66 HLQRPDRA-ILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILE-MFPRTA 122 L+ D + ++Y+ P V E + G P RR I + + ALEP L E FP T Sbjct: 487 TLEGDDESKRFYLQYSFPPSCVGEAGRVGAPSRREIGHGTLAERALEPILPSEDEFPYT- 545 Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IV 172 + V + +++ + +A + SLAL DAG+P++ +A A G + +G I+ Sbjct: 546 VRVESNITESNGSSSMASVCGGSLALLDAGVPVKCPIAGIAMGMVLDTKEFGGDGTPLIL 605 Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229 D+ ED G+ D VA + +T QMD G +T +A+ A G K + + Sbjct: 606 SDITGSEDASGDMDFKVA--GNADCVTAFQMDIKVGGITLSVMKQALLQAKDGRKIILAE 663 Query: 230 QREAL 234 + L Sbjct: 664 MSKCL 668 >pir||G75320 polynucleotide phosphorylase - Deinococcus radiodurans (strain R1) >gi|6459851|gb|AAF11608.1|AE002042_3 (AE002042) polynucleotide phosphorylase [Deinococcus radiodurans] Length = 810 Score = 78.8 bits (191), Expect = 6e-14 Identities = 76/247 (30%), Positives = 116/247 (46%), Gaps = 19/247 (7%) Query: 2 MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRE 61 +EK E +LI E R DGR +RPI +E L A+GSA G+ +++ E Sbjct: 335 VEKRELRRLILEENLRADGRDSKTVRPIWIEARPLPTAHGSAVFTRGETQVLGVTTLGTE 394 Query: 62 -----LHPKHLQRPDRAILRVRYNMAPFSVEERKK-PGPDRRSIEISKVIKGALEPAL-I 114 + + D+ +L YN P+S E K+ G RR I + K A+ L Sbjct: 395 RDEILIDDLTAESGDKFLL--HYNFPPYSTGEVKRMGGQSRREIGHGNLAKRAIRAVLPS 452 Query: 115 LEMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE--- 170 E FP I V +VL+++ + + + A +L+L DAG+P++ VA A G + EG+ Sbjct: 453 FEEFP-YVIRVVGDVLESNGSSSMGTVCAGTLSLMDAGVPLKAPVAGVAMGLVMEGDNYR 511 Query: 171 IVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVY 227 ++ D+ ED G+ D V +T LQMD G +T EA+ A +G + Sbjct: 512 VLTDILGLEDALGDMDFKVC--GTAEGVTALQMDIKVGGITPQIMREALAQAKEGRLHIL 569 Query: 228 QKQREAL 234 K E L Sbjct: 570 GKMAEVL 576 >pir||C82673 ribonuclease PH XF1505 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9106537|gb|AAF84314.1|AE003980_6 (AE003980) ribonuclease PH [Xylella fastidiosa] Length = 241 Score = 77.3 bits (187), Expect = 2e-13 Identities = 68/242 (28%), Positives = 106/242 (43%), Gaps = 25/242 (10%) Query: 14 NGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRA 73 N R GR+ LRP+++E +A GS + +G N ++ P L+ Sbjct: 2 NVSRPSGRQADALRPVRIERAFTCHAEGSVLVSFG-NTLVVCTASVEAKVPVFLRNKGEG 60 Query: 74 ILRVRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIE 128 + Y M P S R + R R++EI ++I AL + I + + Sbjct: 61 WVTAEYGMLPRSTHTRSEREAARGKQAGRTLEIQRLIGRALRTCVDRTALGERTITLDCD 120 Query: 129 VLQADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNK 177 VLQAD GTR A IT A +AL DA P+ VAA + G G VLDL+ Sbjct: 121 VLQADGGTRTAAITGAYVALVDAVRCLEQRGQLKKSPLIGAVAAVSVGIYRGMPVLDLDY 180 Query: 178 EEDNYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEA-----VKLAIKGAKAVYQKQRE 232 ED+ + D+ V + ++ ++++ G + F + LA +G ++ QRE Sbjct: 181 PEDSDCDTDMNVV---MNDEGGVIELQGTAEQQAFRRGELDMLLALAERGTAMLFDIQRE 237 Query: 233 AL 234 AL Sbjct: 238 AL 239 >pir||A26118 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain - Escherichia coli >gi|551833|gb|AAA83905.1| (J02638) polynucleotide phosphorilase [Escherichia coli] Length = 711 Score = 76.9 bits (186), Expect = 2e-13 Identities = 65/199 (32%), Positives = 104/199 (51%), Gaps = 16/199 (8%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK--IIAAVYGPRE---LHPKHLQRPD 71 RIDGR+K +R + + GVL +GSA G+ + + A + R+ L +R D Sbjct: 315 RIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLRTARDAQVLDELMGERTD 374 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEV 129 + YN P+SV E G P RR I ++ K G L ++ FP T + V E+ Sbjct: 375 TFLFH--YNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYT-VRVVSEI 431 Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEA 185 +++ + +A + ASLA DAG+P++ VA A G + EG+ ++ D+ +ED+ G+ Sbjct: 432 TESNGSSSMASVCGASLASMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDM 491 Query: 186 DVPVAIMPLKNDITLLQMD 204 D VA ++ I+ LQMD Sbjct: 492 DFKVA--GSRDGISALQMD 508 >pir||E82298 polyribonucleotide nucleotidyltransferase VC0647 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655083|gb|AAF93813.1| (AE004150) polyribonucleotide nucleotidyltransferase [Vibrio cholerae] Length = 709 Score = 76.9 bits (186), Expect = 2e-13 Identities = 71/236 (30%), Positives = 117/236 (49%), Gaps = 21/236 (8%) Query: 2 MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPR 60 +EK + I RIDGR+K +R + + GVL +GSA G+ + ++ A G + Sbjct: 301 LEKTVVRRSIIAGNPRIDGREKDMVRALDVRTGVLPRTHGSALFTRGETQALVTATLGTQ 360 Query: 61 E----LHPKHLQRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALIL 115 + ++ D +L YN P+ V E G P RR I ++ K + + Sbjct: 361 RDAQIIDELTGEKKDHFLLH--YNFPPYCVGETGFVGSPKRREIGHGRLAKRGIAAVMPS 418 Query: 116 -EMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE---- 170 E FP T + V E+ +++ + +A + +SLAL DAG+P++ VA A G ++ E Sbjct: 419 PEEFPYT-VRVVSEITESNGSSSMASVCGSSLALMDAGVPIKASVAGIAMGLVKEENDFV 477 Query: 171 IVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLTKDEFI--EAVKLAIKGAK 224 ++ D+ +ED+ G+ D VA +T LQMD K E I E +++A+ AK Sbjct: 478 VLSDILGDEDHLGDMDFKVA--GTATGVTALQMD---IKIEGITKEIMQIALNQAK 528 >pir||C71269 probable polyribonucleotide nucleotidyltransferase (pnp) - syphilis spirochete >gi|3323203|gb|AAC26576.1| (AE001258) polyribonucleotide nucleotidyltransferase (pnp) [Treponema pallidum] Length = 702 Score = 76.5 bits (185), Expect = 3e-13 Identities = 65/201 (32%), Positives = 100/201 (49%), Gaps = 13/201 (6%) Query: 13 ENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV----YGPRELHPKHLQ 68 + G RIDGR +RPI EVGVL +GSA G+ + +A V +++ ++ Sbjct: 310 DRGLRIDGRAIDAIRPIACEVGVLPRPHGSAVFTRGETQSLAVVTLGAMSDGQVY-DDIE 368 Query: 69 RPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFI 127 R + YN PFSV E + G RR I + +L + E FP T + V Sbjct: 369 GDRRENFILHYNFPPFSVGEIGRMGVGRREIGHGCLAHRSLSAVIPDPEQFPYT-VRVVS 427 Query: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEG----EIVLDLNKEEDNYG 183 E+L+++ + +A + + +L+L AG+P++ VA A G I I+ D+ EED+ G Sbjct: 428 EILESNGSSSMATVCSGTLSLLHAGVPIKKPVAGIAMGLITDGVRYAILSDILGEEDHLG 487 Query: 184 EADVPVAIMPLKNDITLLQMD 204 + D VA + IT QMD Sbjct: 488 DMDFKVA--GTCDGITGFQMD 506 >pir||H69190 conserved hypothetical protein MTH682 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621767|gb|AAB85187.1| (AE000848) conserved protein [Methanobacterium thermoautotrophicum] Length = 271 Score = 76.1 bits (184), Expect = 4e-13 Identities = 57/238 (23%), Positives = 106/238 (43%), Gaps = 33/238 (13%) Query: 14 NGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRA 73 N RIDGR +E R I +E GV+ A GS+ ++ G +II V ++ P+ Sbjct: 22 NKERIDGRSLHEFRDISIETGVISKAEGSSRVKLGNTQIIVGV--KPQIGEPFPDTPEMG 79 Query: 74 ILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAID--------V 125 ++ + P + + PD RS+E+S+V+ + + ++++ I+ + Sbjct: 80 VILTNSELLPMASPTFEPGPPDERSVELSRVVDRCIRESRMIDLEKLCIIEGSKVWMLFL 139 Query: 126 FIEVLQADAGTRVAGITAASLALADAGIPMRDL--------------------VAACAAG 165 + ++ D A + A AL D IP ++ C Sbjct: 140 DLHIIDYDGNLFDAAVLATVAALLDTRIPAAEVEDGEVVINREKMQPLPVNRKALMCTFA 199 Query: 166 KIEGEIVLDLNKEEDNYGEADVPVAIMPLKNDITLLQM--DGYLTKDEFIEAVKLAIK 221 KI EIVLD + EE++ A + + + + I +Q +G LT+D+ ++AV +A++ Sbjct: 200 KIGNEIVLDPSLEEEDILTARISIGVTE-EGSICAMQKGGEGPLTRDDVLKAVSIAVE 256 >pir||G81725 polyribonucleotide nucleotidyltransferase TC0230 [imported] - Chlamydia muridarum (strain Nigg) >gi|7190270|gb|AAF39102.1| (AE002290) polyribonucleotide nucleotidyltransferase [Chlamydia muridarum] Length = 693 Score = 75.3 bits (182), Expect = 6e-13 Identities = 64/204 (31%), Positives = 99/204 (48%), Gaps = 12/204 (5%) Query: 10 LIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRELHPK--H 66 LI + G R+DGR E+RPI +EV L +GS G+ + +A G + + Sbjct: 307 LIRDLGIRVDGRSTTEIRPISIEVSFLPRTHGSCLFTRGETQSVAVCTLGGESMAQRFED 366 Query: 67 LQRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAID 124 L A ++Y PFSV E + G P RR I K+ + AL L FP T + Sbjct: 367 LNGDGAARFYLQYFFPPFSVGEVGRIGSPGRREIGHGKLAEKALSHVLPEASRFPYT-VR 425 Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI----EGEIVLDLNKEED 180 V + +++ + +A + L+L DAG+P++ VA A G I + ++ D++ ED Sbjct: 426 VESNITESNGSSSMASVCGGCLSLMDAGVPIKAPVAGIAMGLILDQDKAIVLSDISGIED 485 Query: 181 NYGEADVPVAIMPLKNDITLLQMD 204 + G+ D VA + IT QMD Sbjct: 486 HLGDMDFKVA--GTEEGITAFQMD 507 >pir||F82831 polynucleotide phosphorylase XF0239 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9105050|gb|AAF83052.1|AE003877_7 (AE003877) polynucleotide phosphorylase [Xylella fastidiosa] Length = 719 Score = 75.3 bits (182), Expect = 6e-13 Identities = 63/197 (31%), Positives = 98/197 (48%), Gaps = 12/197 (6%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPD---RA 73 RIDGR +RPI ++VGVL +GS G+ + I + + + Sbjct: 335 RIDGRSLEAVRPITVKVGVLPRVHGSGLFTRGETQAIVVTTLGTARDGQVIDAVTGEYKE 394 Query: 74 ILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIK-GALEPALILEMFPRTAIDVFIEVLQ 131 YN P+SV E + G P RR I ++ + G L L+ FP T I V E+ + Sbjct: 395 NFLFHYNFPPYSVGECGRFGVPKRREIGHGRLARRGVLAVMPSLDEFPYT-IRVVSEITE 453 Query: 132 ADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEADV 187 ++ + +A + +SLAL DAG+P++ VA A G + EGE ++ D+ +ED+ G+ D Sbjct: 454 SNGSSSMASVCGSSLALMDAGVPVKAPVAGIAMGLVKEGERFVVLSDILGDEDHLGDMDF 513 Query: 188 PVAIMPLKNDITLLQMD 204 VA ++ LQMD Sbjct: 514 KVA--GTSEGVSALQMD 528 >sp|P44584|PNP_HAEIN POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (POLYNUCLEOTIDE PHOSPHORYLASE) (PNPASE) >gi|1075159|pir||E64056 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain - Haemophilus influenzae (strain Rd KW20) >gi|1573193|gb|AAC21898.1| (U32709) polynucleotide phosphorylase (pnp) [Haemophilus influenzae Rd] Length = 709 Score = 75.3 bits (182), Expect = 6e-13 Identities = 68/222 (30%), Positives = 110/222 (48%), Gaps = 21/222 (9%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL-----QRPD 71 RIDGR +R + + GVL +GSA G+ + +A E + + +R D Sbjct: 314 RIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGERQD 373 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEV 129 + YN P+SV E G P RR I ++ K + + L FP + V E+ Sbjct: 374 HFLFH--YNFPPYSVGETGMIGSPKRREIGHGRLAKRGVAAVMPSLAEFPYV-VRVVSEI 430 Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEEDNYGEA 185 +++ + +A + ASLAL DAG+P++ VA A G ++ E ++ D+ +ED+ G+ Sbjct: 431 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDM 490 Query: 186 DVPVAIMPLKNDITLLQMDGYLTKDEFI--EAVKLAIKGAKA 225 D VA + +T LQMD K E I E +++A+ AK+ Sbjct: 491 DFKVA--GTREGVTALQMD---IKIEGITPEIMQIALNQAKS 527 >sp|Q9ZCT5|RNPH_RICPR RIBONUCLEASE PH (RNASE PH) (TRNA NUCLEOTIDYLTRANSFERASE) >gi|7435287|pir||C71668 ribonuclease ph (rph) RP628 - Rickettsia prowazekii >gi|3861169|emb|CAA15069.1| (AJ235272) RIBONUCLEASE PH (rph) [Rickettsia prowazekii] Length = 240 Score = 75.3 bits (182), Expect = 6e-13 Identities = 67/239 (28%), Positives = 107/239 (44%), Gaps = 25/239 (10%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R GRK +LRPI +E+ L NA GS I+ G ++ + + P L+ ++ + Sbjct: 2 RQSGRKSNQLRPISLELSPLINAEGSCLIKIGNTHVMCSATCETTV-PPFLRGQNQGWIT 60 Query: 77 VRYNMAPFSVEERKK-----PGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y M P S R K R+ EI ++I A+ + L+ I + +V+ Sbjct: 61 AEYGMIPGSTSHRIKREAALGKQGGRTQEIQRLIGRAMRCVINLQKLGERQIIIDCDVIN 120 Query: 132 ADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEED 180 AD GTR A IT + +AL A P+ +AA + G +G VLDL+ ED Sbjct: 121 ADGGTRTAAITGSYVALHLAIRSLMKKRILKVNPLISQIAAISCGIYKGNAVLDLDYLED 180 Query: 181 NYGEADVPVAIMPLKNDITLLQMDGYLTK-----DEFIEAVKLAIKGAKAVYQKQREAL 234 + E D N L+++ G K ++F+ +KLA G +++ Q + L Sbjct: 181 SDAEVDSNFVFACNGN---LIEVQGTAEKEPFSEEQFLAMLKLAKSGVVELFKLQNQVL 236 >pir||T48631 polynucleotide phosphorylase - Arabidopsis thaliana >gi|4971998|emb|CAB43864.1| (Y14685) polynucleotide phosphorylase [Arabidopsis thaliana] >gi|4972000|emb|CAB43865.1| (Y14686) polynucleotide phosphorylase [Arabidopsis thaliana] >gi|7573307|emb|CAB87625.1| (AL163792) polynucleotide phosphorylase [Arabidopsis thaliana] Length = 991 Score = 74.9 bits (181), Expect = 8e-13 Identities = 66/207 (31%), Positives = 99/207 (46%), Gaps = 19/207 (9%) Query: 14 NGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVY--GPRELHP-KHLQRP 70 +G R+DGR E+RPI E L +GSA G +++ V P E L P Sbjct: 361 DGFRVDGRHVDEVRPIYCESHYLPALHGSALFSRGDTQVLCTVTLGAPAEAQSLDSLVGP 420 Query: 71 DRAILRVRYNMAPFSVEE-RKKPGPDRRSIEISKVIKGALEPALILE-MFPRTAIDVFIE 128 + + Y+ P+ E K+ G +RR + + + AL L E FP T I + E Sbjct: 421 PKKRFMLHYSFPPYCTNEVGKRGGLNRREVGHGTLAEKALLAVLPPEEAFPYT-IRINSE 479 Query: 129 VLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI------EGE-----IVLDLNK 177 V+ +D T +A + S+AL DAGIP+R VA + G I GE IV D+ Sbjct: 480 VMSSDGSTSMASVCGGSMALMDAGIPLRAHVAGVSVGLITDVDPSSGEIKDYRIVTDILG 539 Query: 178 EEDNYGEADVPVAIMPLKNDITLLQMD 204 ED+ G+ D +A ++ +T +Q+D Sbjct: 540 LEDHLGDMDFKIA--GTRDGVTAIQLD 564 >pir||T50343 low homolog to ribonuclease ph-like protein [imported] - fission yeast (Schizosaccharomyces pombe) >gi|6983772|emb|CAB75416.1| (AL139314) low similarity to ribonuclease ph-like protein [Schizosaccharomyces pombe] Length = 257 Score = 74.9 bits (181), Expect = 8e-13 Identities = 47/135 (34%), Positives = 74/135 (54%), Gaps = 4/135 (2%) Query: 27 RPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFSV 86 R I +++G A GS+Y E K KI V GPR K A L + ++PFS Sbjct: 36 RKIYLKLGWATKAVGSSYFESEKIKIACTVSGPRP--SKTFAFRSSAKLNCEFRLSPFST 93 Query: 87 EERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADA--GTRVAGITAA 144 R+ S++I+ A+ P+++L ++P+++IDV+I+V+++D T A I+ A Sbjct: 94 SVRQGHVQTVEEKSYSQMIEAAISPSILLHLYPKSSIDVYIQVIESDGALATLAAAISCA 153 Query: 145 SLALADAGIPMRDLV 159 S A+ADA I DLV Sbjct: 154 SSAIADANIDCIDLV 168 >gb|AAD28218.1|AF120720_1 (AF120720) ribonuclease PH [Legionella pneumophila] Length = 235 Score = 74.5 bits (180), Expect = 1e-12 Identities = 54/191 (28%), Positives = 91/191 (47%), Gaps = 17/191 (8%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 R R+ +LRP+ + A GS +E+G+ K+I E P+ L+ ++ + Sbjct: 2 RPSNREHDQLRPVTITRNFTNYAEGSVLVEFGQTKVICNA-SIVEGVPRFLKGKNQGWIT 60 Query: 77 VRYNMAPFSVEERKKPGPDR-----RSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQ 131 Y M P + R + + R++EI ++I +L + L++ I + +V+Q Sbjct: 61 AEYGMLPRATHSRTEREASKGKQGGRTLEIQRLIGRSLRACIDLKVLGENTITLDCDVIQ 120 Query: 132 ADAGTRVAGITAASLALADA-----------GIPMRDLVAACAAGKIEGEIVLDLNKEED 180 AD GTR A IT + +A+ DA +P + VAA + G G+ VLDL+ ED Sbjct: 121 ADGGTRTAAITGSCVAMRDAIHWMVQREKIKKMPAFNYVAAVSVGIYRGQPVLDLDYAED 180 Query: 181 NYGEADVPVAI 191 E D+ V + Sbjct: 181 VLAETDMNVVM 191 >gb|AAF68421.1|AF237935_1 (AF237935) polynucleotide phosphorylase [Pasteurella multocida] Length = 684 Score = 74.5 bits (180), Expect = 1e-12 Identities = 67/222 (30%), Positives = 110/222 (49%), Gaps = 21/222 (9%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL-----QRPD 71 RIDGR +R + + GVL +GSA G+ + +A E + + +R D Sbjct: 287 RIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGERSD 346 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEV 129 + YN P+SV E G P RR I ++ K + + L FP + V E+ Sbjct: 347 HFLFH--YNFPPYSVGETGMIGSPKRREIGHGRLAKRGVAAVMPTLAEFPYV-VRVVSEI 403 Query: 130 LQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGE----IVLDLNKEEDNYGEA 185 +++ + +A + ASLAL DAG+P++ VA A G ++ + ++ D+ +ED+ G+ Sbjct: 404 TESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEDEKFVVLSDILGDEDHLGDM 463 Query: 186 DVPVAIMPLKNDITLLQMDGYLTKDEFI--EAVKLAIKGAKA 225 D VA + +T LQMD K E I E +++A+ AK+ Sbjct: 464 DFKVA--GTRTGVTALQMD---IKIEGITAEIMQIALNQAKS 500 >pir||B75378 ribonuclease PH - Deinococcus radiodurans (strain R1) >gi|6459349|gb|AAF11146.1|AE002002_4 (AE002002) ribonuclease PH [Deinococcus radiodurans] Length = 246 Score = 73.7 bits (178), Expect = 2e-12 Identities = 57/185 (30%), Positives = 91/185 (48%), Gaps = 15/185 (8%) Query: 19 DGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVR 78 +GR RP+ ++ GV +A GSA+++ G+ +I+A V + P H++ L Sbjct: 10 EGRDALTPRPVSVQRGVNPHAPGSAHLKMGRTEILATVTLDDKPAP-HMRGKKEGWLTAE 68 Query: 79 YNMAPFSVEERK---KPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAG 135 Y+M P S +R+ + + R EI +++ AL ++ L F + V +VL AD G Sbjct: 69 YSMLPRSTTDRQARERNLQNGRRHEIQRLLGRALRSSMDLRPFKNQTLYVDCDVLVADGG 128 Query: 136 TRVAGITAASLALAD-----------AGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGE 184 TRVA + A AL D + P+ V A + G I E+ +DL+ EED Sbjct: 129 TRVASVLAGHAALHDFCDRLINSGQLSEWPIVHNVGAISVGLIGDELRVDLDYEEDKVAR 188 Query: 185 ADVPV 189 AD+ V Sbjct: 189 ADLNV 193 >emb|CAA20272.1| (AL031231) guanosine pentaphosphate synthetase/ polyribonucleotide nucleotidyltransferase [Streptomyces coelicolor A3(2)] Length = 716 Score = 73.4 bits (177), Expect = 2e-12 Identities = 69/217 (31%), Positives = 102/217 (46%), Gaps = 19/217 (8%) Query: 16 RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72 +RIDGR ++R + EV + +GSA E G+ +I+ E L R Sbjct: 338 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTR 397 Query: 73 AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130 YN P+SV E + G P RR I + + A+ P L E FP AI E L Sbjct: 398 KRYMHNYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 456 Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182 ++ T + + A++++L +AG+P++ VA A G I EI + D+ ED + Sbjct: 457 GSNGSTSMGSVCASTMSLLNAGVPLKAPVAGIAMGLISQEINGETHYVALTDILGAEDAF 516 Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219 G+ D VA K +T LQ+D TK + I A LA Sbjct: 517 GDMDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 548 >pir||T10932 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) alpha chain [similarity] - Streptomyces coelicolor Length = 739 Score = 73.4 bits (177), Expect = 2e-12 Identities = 69/217 (31%), Positives = 102/217 (46%), Gaps = 19/217 (8%) Query: 16 RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72 +RIDGR ++R + EV + +GSA E G+ +I+ E L R Sbjct: 338 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTR 397 Query: 73 AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130 YN P+SV E + G P RR I + + A+ P L E FP AI E L Sbjct: 398 KRYMHNYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 456 Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182 ++ T + + A++++L +AG+P++ VA A G I EI + D+ ED + Sbjct: 457 GSNGSTSMGSVCASTMSLLNAGVPLKAPVAGIAMGLISQEINGETHYVALTDILGAEDAF 516 Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219 G+ D VA K +T LQ+D TK + I A LA Sbjct: 517 GDMDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 548 >pdb|1E3P|A Chain A, Tungstate Derivative Of Streptomyces Antibioticus Pnpase Gpsi Enzyme Length = 757 Score = 73.4 bits (177), Expect = 2e-12 Identities = 69/217 (31%), Positives = 102/217 (46%), Gaps = 19/217 (8%) Query: 16 RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72 +RIDGR ++R + EV + +GSA E G+ +I+ E L R Sbjct: 355 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTR 414 Query: 73 AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130 YN P+SV E + G P RR I + + A+ P L E FP AI E L Sbjct: 415 KRYMHNYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 473 Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182 ++ T + + A++++L +AG+P++ VA A G I EI + D+ ED + Sbjct: 474 GSNGSTSMGSVCASTMSLLNAGVPLKAPVAGIAMGLISQEINGETHYVALTDILGAEDAF 533 Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219 G+ D VA K +T LQ+D TK + I A LA Sbjct: 534 GDMDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 565 >pir||T44900 probable polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) [imported] - Mycobacterium leprae >gi|2342619|emb|CAB11392.1| (Z98741) guanosine pentaphosphate synthetase/ polyribonucleotide nucleotidyltransferase [Mycobacterium leprae] Length = 777 Score = 73.0 bits (176), Expect = 3e-12 Identities = 64/208 (30%), Positives = 99/208 (46%), Gaps = 20/208 (9%) Query: 14 NGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQR--PD 71 N RIDGR ++R + EV V+ A+GSA E G+ +I+ + + P+ Sbjct: 354 NHFRIDGRGITDIRALSAEVAVVPRAHGSALFERGETQILGVTTLDMVKMAQQIDSLGPE 413 Query: 72 RAILRVR-YNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIE 128 + + YN PFS E + G P RR I + + AL P L +E FP AI E Sbjct: 414 TSKRYMHHYNFPPFSTGETGRVGSPKRREIGHGALAERALVPVLPSVEEFPY-AIRQVSE 472 Query: 129 VLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKE---------- 178 L ++ T + + A++LAL +AG+P++ VA A G + ++ D E Sbjct: 473 ALGSNGSTSMGSVCASTLALLNAGVPLKAPVAGIAMGLVSDDVEFDGGTERRFVTLTDIL 532 Query: 179 --EDNYGEADVPVAIMPLKNDITLLQMD 204 ED +G+ D A K+ +T LQ+D Sbjct: 533 GAEDAFGDMDFKCA--GTKDFVTALQLD 558 >gb|AAF00646.1|AC009540_23 (AC009540) putative polynucleotide phosphorylase [Arabidopsis thaliana] >gi|6091752|gb|AAF03462.1|AC009327_1 (AC009327) putative polynucleotide phosphorylase [Arabidopsis thaliana] Length = 948 Score = 72.6 bits (175), Expect = 4e-12 Identities = 74/234 (31%), Positives = 116/234 (48%), Gaps = 26/234 (11%) Query: 11 IDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK--HL 67 I E G+R DGR E+RPI G+L A+GS G+ + +A V G +++ + +L Sbjct: 467 IVEGGKRSDGRTLDEIRPINSRCGLLPRAHGSTLFTRGETQALAVVTLGDKQMAQRIDNL 526 Query: 68 QRPDR-AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALIL-EMFPRTAID 124 + D ++Y P SV E + G P RR I + + ALE L + FP T I Sbjct: 527 EGSDEYKRFYLQYTFPPSSVGEVGRIGAPSRREIGHGTLAERALETILPSDDDFPYT-IR 585 Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IVLD 174 V V++++ + +A + LAL DAG+P++ VA A G + +G I+ D Sbjct: 586 VESTVIESNGSSSMASVCGGCLALQDAGVPVKCSVAGIAMGMVWDTEEFGGDGSPLILSD 645 Query: 175 LNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKA 225 + ED G+ D VA ++ +T QMD G +T +E ++ A+ AKA Sbjct: 646 ITGAEDASGDMDFKVA--GNEDGVTAFQMDIKVGGIT----LEIMEKALIQAKA 693 >emb|CAB85703.1| (AJ252123) putative polynucleotide phosphorylase [Arabidopsis thaliana] Length = 922 Score = 72.6 bits (175), Expect = 4e-12 Identities = 74/234 (31%), Positives = 116/234 (48%), Gaps = 26/234 (11%) Query: 11 IDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV-YGPRELHPK--HL 67 I E G+R DGR E+RPI G+L A+GS G+ + +A V G +++ + +L Sbjct: 441 IVEGGKRSDGRTLDEIRPINSRCGLLPRAHGSTLFTRGETQALAVVTLGDKQMAQRIDNL 500 Query: 68 QRPDR-AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALIL-EMFPRTAID 124 + D ++Y P SV E + G P RR I + + ALE L + FP T I Sbjct: 501 EGSDEYKRFYLQYTFPPSSVGEVGRIGAPSRREIGHGTLAERALETILPSDDDFPYT-IR 559 Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IVLD 174 V V++++ + +A + LAL DAG+P++ VA A G + +G I+ D Sbjct: 560 VESTVIESNGSSSMASVCGGCLALQDAGVPVKCSVAGIAMGMVWDTEEFGGDGSPLILSD 619 Query: 175 LNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKA 225 + ED G+ D VA ++ +T QMD G +T +E ++ A+ AKA Sbjct: 620 ITGAEDASGDMDFKVA--GNEDGVTAFQMDIKVGGIT----LEIMEKALIQAKA 667 >gb|AAB17498.1| (U19858) guanosine pentaphosphate synthetase [Streptomyces antibioticus] Length = 740 Score = 72.2 bits (174), Expect = 5e-12 Identities = 69/217 (31%), Positives = 101/217 (45%), Gaps = 19/217 (8%) Query: 16 RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72 +RIDGR ++R + EV + +GSA E G+ +I+ E L R Sbjct: 338 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTR 397 Query: 73 AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130 YN P SV E + G P RR I + + A+ P L E FP AI E L Sbjct: 398 KPYMHNYNFPPISVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 456 Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182 ++ T + + A++++L +AG+P++ VA A G I EI + D+ ED + Sbjct: 457 GSNGSTSMGSVCASTMSLLNAGVPLKAPVAGIAMGLISQEINGETHYVALTDILGAEDAF 516 Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219 G+ D VA K +T LQ+D TK + I A LA Sbjct: 517 GDMDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 548 >pir||F70883 probable guanosine pentaphosphate synthetase and polyribonucleotide nucleotidyltransferase - Mycobacterium tuberculosis (strain H37RV) >gi|2624305|emb|CAA15578.1| (AL008967) gpsI [Mycobacterium tuberculosis] Length = 752 Score = 72.2 bits (174), Expect = 5e-12 Identities = 64/209 (30%), Positives = 100/209 (47%), Gaps = 24/209 (11%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQR--PDRAI 74 RIDGR ++R + EV V+ A+GSA E G+ +I+ + + P+ + Sbjct: 346 RIDGRGITDIRALSAEVAVVPRAHGSALFERGETQILGVTTLDMIKMAQQIDSLGPETSK 405 Query: 75 LRVR-YNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVLQ 131 + YN PFS E + G P RR I + + AL P L +E FP AI E L Sbjct: 406 RYMHHYNFPPFSTGETGRVGSPKRREIGHGALAERALVPVLPSVEEFPY-AIRQVSEALG 464 Query: 132 ADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI----------------VLDL 175 ++ T + + A++LAL +AG+P++ VA A G + +I + D+ Sbjct: 465 SNGSTSMGSVCASTLALLNAGVPLKAPVAGIAMGLVSDDIQVEGAVDGVVERRFVTLTDI 524 Query: 176 NKEEDNYGEADVPVAIMPLKNDITLLQMD 204 ED +G+ D VA K+ +T LQ+D Sbjct: 525 LGAEDAFGDMDFKVA--GTKDFVTALQLD 551 >pdb|1E3H|A Chain A, Semet Derivative Of Streptomyces Antibioticus PnpaseGPSI Enzyme Length = 757 Score = 72.2 bits (174), Expect = 5e-12 Identities = 69/217 (31%), Positives = 100/217 (45%), Gaps = 19/217 (8%) Query: 16 RRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAV---YGPRELHPKHLQRPDR 72 +RIDGR ++R + EV + +GSA E G+ +I+ E L R Sbjct: 355 KRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNXLRXEQQLDTLSPVTR 414 Query: 73 AILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPAL-ILEMFPRTAIDVFIEVL 130 YN P+SV E + G P RR I + + A+ P L E FP AI E L Sbjct: 415 KRYXHNYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPY-AIRQVSEAL 473 Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEI--------VLDLNKEEDNY 182 ++ T + A++ +L +AG+P++ VA A G I EI + D+ ED + Sbjct: 474 GSNGSTSXGSVCASTXSLLNAGVPLKAPVAGIAXGLISQEINGETHYVALTDILGAEDAF 533 Query: 183 GEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLA 219 G+ D VA K +T LQ+D TK + I A LA Sbjct: 534 GDXDFKVA--GTKEFVTALQLD---TKLDGIPASVLA 565 >pir||E71463 probable polyribonucleotide nucleotidyltransferase - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3329314|gb|AAC68439.1| (AE001357) Polyribonucleotide Nucleotidyltransferase [Chlamydia trachomatis] Length = 695 Score = 71.0 bits (171), Expect = 1e-11 Identities = 64/208 (30%), Positives = 97/208 (45%), Gaps = 20/208 (9%) Query: 10 LIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRELHPK--H 66 LI + G R+DGR E+RPI +E L +GS G+ + +A G + + Sbjct: 308 LIQDLGIRVDGRTTTEIRPISIETPFLPRTHGSCLFTRGETQSMAVCTLGGENMAQRFED 367 Query: 67 LQRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILEMFPRTAIDV 125 L A ++Y PFSV E + G P RR I K+ + AL L P T+ Sbjct: 368 LNGDGAARFYLQYFFPPFSVGEVGRIGSPGRREIGHGKLAEKALSHVL-----PETSRFP 422 Query: 126 FI-----EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI----EGEIVLDLN 176 +I + +++ + +A + LAL DAG+P++ VA A G I + I+ D++ Sbjct: 423 YIIRLESNITESNGSSSMASVCGGCLALMDAGVPIKAPVAGIAMGLILDRDQAIILSDIS 482 Query: 177 KEEDNYGEADVPVAIMPLKNDITLLQMD 204 ED+ G+ D VA IT QMD Sbjct: 483 GIEDHLGDMDFKVA--GTAKGITAFQMD 508 >pir||T06540 polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) - garden pea >gi|2286200|gb|AAC50039.1| (AF010578) polynucleotide phosphorylase [Pisum sativum] Length = 897 Score = 70.6 bits (170), Expect = 2e-11 Identities = 71/245 (28%), Positives = 115/245 (45%), Gaps = 22/245 (8%) Query: 9 KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRELHPK-- 65 K I E G+R DGR E+RPI +L A+GSA G+ + +A A G ++ + Sbjct: 436 KRIVEGGKRSDGRTPKEIRPINSSCSILPRAHGSALFTRGETQALAVATLGDNKMAQRIN 495 Query: 66 -HLQRPDRAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILEM-FPRTA 122 ++ D ++Y+ P V E + G P RR I + + +LE L + FP T Sbjct: 496 NLIEVDDYKRFYLQYSFPPSCVGEAGRIGAPSRREIGHGMLAERSLETILPSDNDFPYT- 554 Query: 123 IDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI--------EGE--IV 172 I V + +++ + +A + LAL DAG+P++ +A A G + +G I+ Sbjct: 555 IRVESTITESNGSSSMASVCGGCLALQDAGVPIKCSIAGIAMGLVLDTKEFGGDGTPLIL 614 Query: 173 LDLNKEEDNYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQK 229 D+ ED G+ D VA ++ IT QMD +T EA+ A G K + + Sbjct: 615 SDITGSEDASGDMDFKVA--GNEDGITAFQMDIKVAGITLPIMREALLQARDGRKHILGE 672 Query: 230 QREAL 234 ++L Sbjct: 673 MMKSL 677 >pir||H81943 probable polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) NMA0969 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379672|emb|CAB84239.1| (AL162754) putative polyribonucleotide nucleotidyltransferase [Neisseria meningitidis Z2491] Length = 706 Score = 70.6 bits (170), Expect = 2e-11 Identities = 61/198 (30%), Positives = 95/198 (47%), Gaps = 14/198 (7%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRE----LHPKHLQRPD 71 RIDGR +RP+ ++ GVL +GSA G+ + +A A G + + D Sbjct: 316 RIDGRDTRTVRPLNIQTGVLPRTHGSALFTRGETQALAVATLGTSRDEQIIDALSGEYTD 375 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVL 130 R +L YN P+S E + G P RR I ++ K AL L + V E+ Sbjct: 376 RFML--HYNFPPYSTGEVGRMGAPKRREIGHGRLAKRALLAVLPKPEDFSYTMRVVSEIT 433 Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEAD 186 +++ + +A + L+L AG+P++ VA A G I EG ++ D+ +ED+ G+ D Sbjct: 434 ESNGSSSMASVCGGCLSLLSAGVPLKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMD 493 Query: 187 VPVAIMPLKNDITLLQMD 204 VA +T LQMD Sbjct: 494 FKVA--GTTEGVTALQMD 509 >pir||E64671 polynucleotide phosphorylase - Helicobacter pylori (strain 26695) >gi|2314375|gb|AAD08258.1| (AE000627) polynucleotide phosphorylase (pnp) [Helicobacter pylori 26695] Length = 688 Score = 69.5 bits (167), Expect = 4e-11 Identities = 72/248 (29%), Positives = 117/248 (47%), Gaps = 17/248 (6%) Query: 2 MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPR 60 ++K E ++I ++ R D R E+RPI +E +L A+ S G+ + ++ V G Sbjct: 299 VKKTEIRRMIIKDKIRPDKRALEEVRPILIESDLLPMAHSSILFTRGQTQSLVVGVLGTD 358 Query: 61 ELHPKHLQRPDRAILRVR----YNMAPFSVEERKKPGP-DRRSIEISKVIKGALEPALIL 115 H +A ++ R YN PF V E G RR + + K ALE ++ Sbjct: 359 NDAQTHESLEHKAPIKERFMFHYNFPPFCVGEASSIGAASRRELGHGNLAKRALETSIKN 418 Query: 116 EMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---I 171 + I + E+L+++ + +A + A SLAL +G+ + DLVA A G + EG+ I Sbjct: 419 K---EQVIRLVSEILESNGSSSMASVCAGSLALYASGVEIYDLVAGVAMGMVSEGQDHAI 475 Query: 172 VLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLT--KDEFIEAVKLAIKGAKAVYQK 229 + D++ ED G+ D +A IT +QMD ++ K E + L K A+ K Sbjct: 476 LSDISGLEDAEGDMDFKIA--GNLEGITAMQMDTKMSGIKLEILYQALLQAKEARKHILK 533 Query: 230 QREALKEK 237 KEK Sbjct: 534 IMHEAKEK 541 >pir||G72009 polyribonucleotide nucleotidyltransferase CP0855 [imported] - Chlamydophila pneumoniae (strains CWL029 and AR39) >gi|4377328|gb|AAD19136.1| (AE001680) Polyribonucleotide Nucleotidyltransferase [Chlamydophila pneumoniae CWL029] >gi|7189766|gb|AAF38644.1| (AE002244) polyribonucleotide nucleotidyltransferase [Chlamydophila pneumoniae AR39] >gi|8979372|dbj|BAA99206.1| (AP002548) polyribonucleotide nucleotidyltransferase [Chlamydophila pneumoniae J138] Length = 694 Score = 69.5 bits (167), Expect = 4e-11 Identities = 70/246 (28%), Positives = 112/246 (45%), Gaps = 15/246 (6%) Query: 10 LIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAA-VYGPRELHPKHLQ 68 LI + R DGR +RPI +E L +GS G+ + +A G + ++ Sbjct: 308 LIRDREIRADGRSLTTVRPITIETSYLPRTHGSCLFTRGETQTLAVCTLGSEAMAQRYED 367 Query: 69 RPDRAILR--VRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALI-LEMFPRTAID 124 + + ++Y PFSV E + G P RR I K+ + AL AL FP T I Sbjct: 368 LNGEGLSKFYLQYFFPPFSVGEVGRIGSPGRREIGHGKLAEKALSHALPDSATFPYT-IR 426 Query: 125 VFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI---EGEIVL-DLNKEED 180 + + +++ + +A + LAL DAG+P+ +A A G I +G I+L D++ ED Sbjct: 427 IESNITESNGSSSMASVCGGCLALMDAGVPISSPIAGIAMGLILDDQGAIILSDISGLED 486 Query: 181 NYGEADVPVAIMPLKNDITLLQMD---GYLTKDEFIEAVKLAIKGAKAVYQKQREALKEK 237 + G+ D +A IT QMD +T +A+ A +G + EAL Sbjct: 487 HLGDMDFKIA--GSGKGITAFQMDIKVEGITPAIMKKALSQAKQGCNDILNIMNEALSAP 544 Query: 238 YLKIAQ 243 ++Q Sbjct: 545 KADLSQ 550 >pir||E71845 polyribonucleotide nucleotidyltransferase - Helicobacter pylori (strain J99) >gi|4155738|gb|AAD06718.1| (AE001541) POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE [Helicobacter pylori J99] Length = 688 Score = 68.3 bits (164), Expect = 8e-11 Identities = 69/248 (27%), Positives = 115/248 (45%), Gaps = 17/248 (6%) Query: 2 MEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNK-IIAAVYGPR 60 ++K E ++I ++ R D R E+RPI +E +L A+ S G+ + ++ V G Sbjct: 299 VKKTEIRRMIIQDKIRPDKRALEEVRPISIESNLLPMAHSSILFTRGQTQSLVVGVLGMD 358 Query: 61 ELHPKHLQRPDRAILRVR----YNMAPFSVEERKKPGP-DRRSIEISKVIKGALEPALIL 115 H +A ++ R YN PF V E G RR + + K ALE ++ Sbjct: 359 NDAQTHENLEHKAPIKERFMFHYNFPPFCVGEASSIGATSRRELGHGNLAKRALETSIKN 418 Query: 116 EMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI----EGEI 171 + I + E+L+++ + +A + A SLAL +G+ + DLVA A G + + I Sbjct: 419 K---EQVIRLVSEILESNGSSSMASVCAGSLALYASGVEIHDLVAGVAMGMVSERQDHAI 475 Query: 172 VLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLT--KDEFIEAVKLAIKGAKAVYQK 229 + D++ ED G+ D +A IT +QMD ++ + E + L K A+ K Sbjct: 476 LSDISGLEDAEGDMDFKIA--GNLEGITAMQMDTKMSGIQLEVLYQALLQAKRARKHILK 533 Query: 230 QREALKEK 237 KEK Sbjct: 534 IMHEAKEK 541 >pir||C81161 polyribonucleotide nucleotidyltransferase NMB0758 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7225988|gb|AAF41171.1| (AE002430) polyribonucleotide nucleotidyltransferase [Neisseria meningitidis MC58] Length = 707 Score = 68.3 bits (164), Expect = 8e-11 Identities = 60/198 (30%), Positives = 94/198 (47%), Gaps = 14/198 (7%) Query: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIA-AVYGPRE----LHPKHLQRPD 71 RIDGR +RP+ ++ VL +GSA G+ + +A A G + + D Sbjct: 317 RIDGRDTRTVRPLNIQTSVLPRTHGSALFTRGETQALAVATLGTSRDEQIIDALSGEYTD 376 Query: 72 RAILRVRYNMAPFSVEERKKPG-PDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVL 130 R +L YN P+S E + G P RR I ++ K AL L + V E+ Sbjct: 377 RFML--HYNFPPYSTGEVGRMGAPKRREIGHGRLAKRALLAVLPKPEDFSYTMRVVSEIT 434 Query: 131 QADAGTRVAGITAASLALADAGIPMRDLVAACAAGKI-EGE---IVLDLNKEEDNYGEAD 186 +++ + +A + L+L AG+P++ VA A G I EG ++ D+ +ED+ G+ D Sbjct: 435 ESNGSSSMASVCGGCLSLLSAGVPLKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMD 494 Query: 187 VPVAIMPLKNDITLLQMD 204 VA +T LQMD Sbjct: 495 FKVA--GTTEGVTALQMD 510 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.317 0.137 0.379 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89261604 Number of Sequences: 2977 Number of extensions: 3668329 Number of successful extensions: 9866 Number of sequences better than 1.0e-10: 86 Number of HSP's better than 0.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 72 Number of HSP's that attempted gapping in prelim test: 9718 Number of HSP's gapped (non-prelim): 110 length of query: 249 length of database: 189,106,746 effective HSP length: 58 effective length of query: 191 effective length of database: 154,394,500 effective search space: 29489349500 effective search space used: 29489349500 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 164 (68.3 bits)