BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0425 (rpoA2) DE:DNA-directed RNA polymerase, subunit A''
(rpoA2)
(397 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75182 DNA-directed RNA polymerase, chain A'' (rpoa2) PAB04... 772 0.0
pir||G71031 probable DNA-directed RNA polymerase subunit A - Pyr... 754 0.0
sp|P29158|RPA2_THECE DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|... 634 0.0
gb|AAK40565.1| DNA-directed RNA polymerase, subunit A'' (rpoA2) ... 397 e-109
sp|P14247|RPA2_METVA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|... 387 e-106
sp|P11514|RPA2_SULAC DNA-DIRECTED RNA POLYMERASE SUBUNIT A" (SUB... 386 e-106
sp|O27126|RPA2_METTH DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|... 385 e-106
gi|11499473 DNA-directed RNA polymerase, subunit A'' (rpoA2) [Ar... 382 e-105
sp|P09847|RPA2_METTW DNA-DIRECTED RNA POLYMERASE SUBUNIT A" (SUB... 377 e-103
sp|Q58446|RPA2_METJA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|... 367 e-101
pir||C33926 DNA-directed RNA polymerase (EC 2.7.7.6) C - Sulfolo... 361 9e-99
sp|P15353|RPA2_HALMO DNA-DIRECTED RNA POLYMERASE SUBUNIT A" (SUB... 340 1e-92
sp|Q03586|RPA2_THEAC DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|... 337 2e-91
emb|CAC11536.1| (AL445064) probable DNA-directed RNA polymerase,... 337 2e-91
pir||C72571 probable DNA-directed RNA polymerase subunit A APE18... 326 2e-88
emb|CAA42846.1| (X60305) subunit A'' of RNA polymerase [Thermoco... 323 2e-87
sp|P15354|RPA2_HALHA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" (SUB... 319 4e-86
pir||D33926 DNA-directed RNA polymerase (EC 2.7.7.6) chain C - H... 302 4e-81
gi|6320061 RNA polymerase II large subunit; Rpo21p [Saccharomyce... 234 2e-60
emb|CAA26904.1| (X03128) put. RNA polymerase II largest subunit ... 234 2e-60
gb|AAF48509.1| (AE003500) CG17209 gene product [Drosophila melan... 223 2e-57
gi|5902062 polymerase (RNA) III (DNA directed) (155kD) [Homo sap... 222 4e-57
gi|11431655 polymerase (RNA) III (DNA directed) (155kD) [Homo sa... 222 7e-57
gb|AAC18417.1| (U90211) RNA polymerase II largest subunit [Acant... 220 2e-56
sp|P36594|RPB1_SCHPO DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 220 2e-56
emb|CAA34086.1| (X15970) RNA polymerase beta' subunit (AA 215) [... 218 8e-56
dbj|BAA96933.1| (AB019231) DNA-directed RNA polymerase II larges... 216 3e-55
sp|O94666|RPC1_SCHPO DNA-DIRECTED RNA POLYMERASE III LARGEST SUB... 215 5e-55
dbj|BAB12227.1| (AB017184) RNA polymerase II largest subunit [As... 214 1e-54
pir||T34157 hypothetical protein C42D4.8 - Caenorhabditis elegan... 212 4e-54
emb|CAB42796.1| (Y18877) largest subunit of the RNA polymerase I... 210 2e-53
emb|CAB42800.1| (Y18876) largest subunit of the RNA polymerase I... 210 2e-53
emb|CAB42797.1| (Y18879) largest subunit of the RNA polymerase I... 210 3e-53
emb|CAB42795.1| (Y18878) largest subunit of the RNA polymerase I... 210 3e-53
gb|AAF48057.1| (AE003486) RpII215 gene product [Drosophila melan... 209 4e-53
sp|P04052|RPB1_DROME DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 209 4e-53
gi|6677795 RNA polymerase II 1 [Mus musculus] >gi|90464|pir||A28... 208 7e-53
gi|4505939 polymerase (RNA) II (DNA directed) polypeptide A (220... 208 7e-53
sp|P08775|RPB1_MOUSE DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 208 7e-53
gb|AAB58418.1| (U37500) RNA polymerase II largest subunit [Mus m... 208 7e-53
dbj|BAA22376.1| (D87293) RNA polymerase II largest subunit [Cric... 208 7e-53
sp|P35084|RPB1_DICDI DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 207 2e-52
sp|P18616|RPB1_ARATH DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 206 3e-52
emb|CAA21466.2| (AL031986) DNA-directed RNA polymerase (EC 2.7.7... 206 3e-52
pir||JDMU1 DNA-directed RNA polymerase (EC 2.7.7.6) II largest c... 206 3e-52
pir||I38186 RNA polymerase II largest subunit - human >gi|825713... 205 6e-52
sp|P31635|RPB0_ARATH DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 204 1e-51
gi|6324690 RNA polymerase III large subunit; Rpo31p [Saccharomyc... 203 4e-51
pir||T29959 DNA-directed RNA polymerase II large subunit ama-1 -... 202 5e-51
pir||S14183 DNA-directed RNA polymerase (EC 2.7.7.6) largest cha... 200 2e-50
pir||T31436 DNA-directed RNA polymerase (EC 2.7.7.6) II largest ... 199 3e-50
pir||T31435 DNA-directed RNA polymerase (EC 2.7.7.6) II largest ... 197 2e-49
sp|P16356|RPB1_CAEEL DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 197 2e-49
gb|AAA30233.1| (M27163) RNA polymerase III [Trypanosoma brucei] 197 2e-49
sp|P08968|RPC1_TRYBB DNA-DIRECTED RNA POLYMERASE III LARGEST SUB... 196 4e-49
pir||T43260 RNA polymerase (EC 2.7.7.-) II - Trichomonas vaginal... 196 5e-49
pir||T43217 RNA polymerase (EC 2.7.7.-) II, largest chain - Porp... 191 9e-48
pir||T43026 probable DNA-directed RNA polymerase (EC 2.7.7.6) II... 191 9e-48
pir||S22812 DNA-directed RNA polymerase (EC 2.7.7.6) III largest... 189 6e-47
sp|P25202|RPC1_GIALA DNA-DIRECTED RNA POLYMERASE III LARGEST SUB... 189 6e-47
gb|AAB51212.1| (U73456) large subunit RNA polymerase II [Terator... 182 8e-45
gb|AAB51211.1| (U73454) large subunit RNA polymerase II [Mesorha... 181 1e-44
gb|AAA50225.1| (U10334) RNA polymerase II, largest subunit [Cras... 181 1e-44
gb|AAA50229.1| (U10338) RNA polymerase II, largest subunit [Ilya... 181 1e-44
gb|AAA50227.1| (U10336) RNA polymerase II, largest subunit [Helo... 178 7e-44
gb|AAC83397.1| (U10331) RNA polymerase II, largest subunit [Arte... 174 1e-42
gb|AAB40621.1| (U61762) RNA polymerase II large subunit [Aduncos... 174 2e-42
gb|AAC47792.2| (AF009163) RNA polymerase II large subunit [Leish... 171 1e-41
gb|AAB40622.1| (U61763) RNA polymerase II large subunit [Zeldia ... 171 1e-41
gb|AAB51213.1| (U73448) large subunit RNA polymerase II [unident... 170 3e-41
gb|AAF36438.1|AF126254_1 (AF126254) RNA polymerase II largest su... 169 6e-41
gb|AAB51210.1| (U73451) large subunit RNA polymerase II [Cruznem... 161 1e-38
sp|P17545|RPB1_TRYBB DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 155 8e-37
sp|P17546|RPB2_TRYBB DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 155 8e-37
pir||B31494 DNA-directed RNA polymerase (EC 2.7.7.6) IIB - Trypa... 155 8e-37
gb|AAA30229.1| (J03157) RNA polymerase IIA largest subunit [Tryp... 155 8e-37
gb|AAA30232.1| (J04841) RNA polymerase IIB largest subunit [Tryp... 155 8e-37
pir||A31494 DNA-directed RNA polymerase (EC 2.7.7.6) IIA - Trypa... 155 8e-37
pir||T31670 DNA-directed RNA polymerase (EC 2.7.7.6) II largest ... 143 3e-33
gb|AAF26622.1|AF138972_1 (AF138972) RNA polymerase II largest su... 126 4e-28
gb|AAF26664.1|AF139014_1 (AF139014) RNA polymerase II largest su... 125 6e-28
gb|AAF26620.1|AF138970_1 (AF138970) RNA polymerase II largest su... 123 4e-27
gb|AAF26638.1|AF138988_1 (AF138988) RNA polymerase II largest su... 123 4e-27
sp|P14248|RPB1_PLAFD DNA-DIRECTED RNA POLYMERASE II LARGEST SUBU... 116 5e-25
pir||T18492 hypothetical protein C0805w - malaria parasite (Plas... 116 5e-25
gb|AAC99803.1| (U24217) RNA polymerase II largest subunit [Kluyv... 113 5e-24
gb|AAC47783.1| (AF009154) RNA polymerase II large subunit [Leish... 110 2e-23
gb|AAC47793.1| (AF009164) RNA polymerase II large subunit [Leish... 110 2e-23
gb|AAC47789.1| (AF009160) RNA polymerase II large subunit [Leish... 110 3e-23
pir||T07796 DNA-directed RNA polymerase (EC 2.7.7.6) largest cha... 109 5e-23
pir||S14181 DNA-directed RNA polymerase (EC 2.7.7.6) largest cha... 109 5e-23
sp|P27625|RPC1_PLAFA DNA-DIRECTED RNA POLYMERASE III LARGEST SUB... 109 7e-23
pir||A45597 DNA-directed RNA polymerase (EC 2.7.7.6) III largest... 109 7e-23
gb|AAC47782.1| (AF009153) RNA polymerase II large subunit [Leish... 109 7e-23
gb|AAC47795.1| (AF009166) RNA polymerase II large subunit [Leish... 109 7e-23
gb|AAC47784.1| (AF009155) RNA polymerase II large subunit [Leish... 108 9e-23
gb|AAC47785.1| (AF009156) RNA polymerase II large subunit [Leish... 108 9e-23
gb|AAC47786.1| (AF009157) RNA polymerase II large subunit [Leish... 108 9e-23
gb|AAC47790.1| (AF009161) RNA polymerase II large subunit [Leish... 108 9e-23
gb|AAC47794.1| (AF009165) RNA polymerase II large subunit [Leish... 108 9e-23
gb|AAC47796.1| (AF009167) RNA polymerase II large subunit [Leish... 108 9e-23
gb|AAC47787.1| (AF009158) RNA polymerase II large subunit [Endot... 108 1e-22
gb|AAA92868.1| (L34213) DNA-dependent RNA polymerase largest sub... 107 2e-22
gb|AAF67243.1| (AF151727) RNA polymerase II large subunit [Leish... 107 2e-22
sp|P91875|RPA1_DROME DNA-DIRECTED RNA POLYMERASE I LARGEST SUBUN... 104 1e-21
gb|AAF58234.1| (AE003814) RpI1 gene product [Drosophila melanoga... 104 2e-21
gi|9628206 RNA polymerase subunit 1 [African swine fever virus] ... 103 4e-21
emb|CAA36734.1| (X52493) DNA-directed RNA polymerase [Glycine max] 99 1e-19
pir||S14182 DNA-directed RNA polymerase (EC 2.7.7.6) largest cha... 99 1e-19
pir||T06754 DNA-directed RNA polymerase I 190K chain homolog F15... 97 3e-19
sp|O54889|RPA1_RAT DNA-DIRECTED RNA POLYMERASE I LARGEST SUBUNIT... 96 7e-19
gi|7661686 DKFZP586M0122 protein [Homo sapiens] >gi|4096591|gb|A... 95 1e-18
gb|AAD09356.1| (U33823) DNA-directed RNA polymerase I largest su... 95 1e-18
gi|11430046 DKFZP586M0122 protein [Homo sapiens] 95 1e-18
gi|6677793 RNA polymerase 1-4 (194 kDa subunit) [Mus musculus] >... 93 4e-18
dbj|BAA82753.1| (AB018418) largest subunit of the DNA-dependent ... 92 1e-17
dbj|BAB15171.1| (AK025568) unnamed protein product [Homo sapiens] 91 2e-17
pir||JS0206 DNA-directed RNA polymerase (EC 2.7.7.6) I 189K chai... 90 5e-17
sp|P15398|RPA1_SCHPO DNA-DIRECTED RNA POLYMERASE I 190 KDA POLYP... 90 5e-17
pir||T19606 hypothetical protein Y48E1A.1 - Caenorhabditis elega... 88 1e-16
gb|AAA34890.1| (J03530) RNA polymerase A(I) large subunit [Sacch... 85 1e-15
gi|6324917 RNA polymerase I subunit 190 (alpha); Rpa190p [Saccha... 85 1e-15
pir||T28156 DNA-directed RNA polymerase homolog - malaria parasi... 79 1e-13
gb|AAC03136.2| (U90037) RNA polymerase II largest subunit [Limul... 77 3e-13
gb|AAC03137.2| (U90038) RNA polymerase II largest subunit [Masti... 76 5e-13
sp|P96177|RPOC_WEIHE DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TR... 76 6e-13
sp|P96178|RPOC_WEIPA DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TR... 76 6e-13
pir||T10908 DNA-directed RNA polymerase (EC 2.7.7.6) beta' chain... 76 8e-13
sp|P47770|RPOC_STAAU DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TR... 76 8e-13
sp|P77839|RPOC_BROTH DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TR... 74 2e-12
emb|CAA61515.1| (X89231) DNA-directed RNA polymerase [Brochothri... 74 2e-12
sp|P16355|RPA1_TRYBB DNA-DIRECTED RNA POLYMERASE I LARGEST SUBUN... 73 4e-12
pir||A34374 DNA-directed RNA polymerase (EC 2.7.7.6) I largest c... 73 4e-12
sp|P94892|RPOC_LEUME DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TR... 73 7e-12
sp|P94899|RPOC_LEUPS DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TR... 73 7e-12
sp|P77879|RPOC_LISIN DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TR... 71 2e-11
>pir||C75182 DNA-directed RNA polymerase, chain A'' (rpoa2) PAB0425 - Pyrococcus
abyssi (strain Orsay) >gi|5458048|emb|CAB49538.1|
(AJ248284) DNA-directed RNA polymerase, subunit A''
(rpoA2) [Pyrococcus abyssi]
Length = 397
Score = 772 bits (1971), Expect = 0.0
Identities = 397/397 (100%), Positives = 397/397 (100%)
Query: 1 MVSSSTIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALV 60
MVSSSTIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALV
Sbjct: 1 MVSSSTIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALV 60
Query: 61 EPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTV 120
EPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTV
Sbjct: 61 EPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTV 120
Query: 121 YLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKV 180
YLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKV
Sbjct: 121 YLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKV 180
Query: 181 LKKLQSSFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEG 240
LKKLQSSFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEG
Sbjct: 181 LKKLQSSFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEG 240
Query: 241 DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGL 300
DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGL
Sbjct: 241 DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGL 300
Query: 301 EVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNL 360
EVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNL
Sbjct: 301 EVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNL 360
Query: 361 SGVIENVLIGQPVPVGTGMVKLTMKLPLRPQKEKEEV 397
SGVIENVLIGQPVPVGTGMVKLTMKLPLRPQKEKEEV
Sbjct: 361 SGVIENVLIGQPVPVGTGMVKLTMKLPLRPQKEKEEV 397
>pir||G71031 probable DNA-directed RNA polymerase subunit A - Pyrococcus
horikoshii >gi|3257972|dbj|BAA30655.1| (AP000006) 397aa
long hypothetical DNA-directed RNA polymerase subunit A
[Pyrococcus horikoshii]
Length = 397
Score = 754 bits (1926), Expect = 0.0
Identities = 382/397 (96%), Positives = 393/397 (98%)
Query: 1 MVSSSTIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALV 60
MVSSSTIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTK EVETIIDEV+KEYE+AL+
Sbjct: 1 MVSSSTIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKVEVETIIDEVIKEYEKALI 60
Query: 61 EPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTV 120
EPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTV
Sbjct: 61 EPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTV 120
Query: 121 YLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKV 180
YLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVE+DPERLEKSGLTMEK+
Sbjct: 121 YLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEVDPERLEKSGLTMEKI 180
Query: 181 LKKLQSSFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEG 240
LKKLQSSFKSAEFE +GYTLIVRPKK EKISDLRRL+EKVKKHRLKGLSGVGKTI+RKEG
Sbjct: 181 LKKLQSSFKSAEFEADGYTLIVRPKKIEKISDLRRLSEKVKKHRLKGLSGVGKTIIRKEG 240
Query: 241 DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGL 300
DEYVIYTEGSNFKQVLKVPGVDPTRT+TNNIHEIAEVLGIEAARNAIIEEI+NTM EQGL
Sbjct: 241 DEYVIYTEGSNFKQVLKVPGVDPTRTRTNNIHEIAEVLGIEAARNAIIEEIINTMHEQGL 300
Query: 301 EVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNL 360
EVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNL
Sbjct: 301 EVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNL 360
Query: 361 SGVIENVLIGQPVPVGTGMVKLTMKLPLRPQKEKEEV 397
SGVIENVLIGQPVPVGTGMVKLTMKLPL+PQKEKEEV
Sbjct: 361 SGVIENVLIGQPVPVGTGMVKLTMKLPLKPQKEKEEV 397
>sp|P29158|RPA2_THECE DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|280352|pir||S25565
DNA-directed RNA polymerase (EC 2.7.7.6) chain A'' -
Thermococcus celer >gi|48142|emb|CAA47724.1| (X67313)
Subunit A'' of DNA-dependent RNA polymerase
[Thermococcus celer]
Length = 393
Score = 634 bits (1618), Expect = 0.0
Identities = 315/395 (79%), Positives = 362/395 (90%), Gaps = 4/395 (1%)
Query: 1 MVSSSTIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALV 60
MV++ TIK +++K +LP+++K+ELY KLI+YN+KYKL KAEV+ IIDE VKEY++AL+
Sbjct: 1 MVAAKTIKGMVDKA--ELPDNIKEELYAKLIEYNKKYKLKKAEVQAIIDETVKEYQKALI 58
Query: 61 EPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTV 120
EPGEA+GTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTP+MTV
Sbjct: 59 EPGEAIGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPIMTV 118
Query: 121 YLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKV 180
YLDEEHRYDREKA EVARRIEGT+LENLAR TT+D++N EFIVEIDPERLEK+GL ME++
Sbjct: 119 YLDEEHRYDREKALEVARRIEGTSLENLARETTIDILNFEFIVEIDPERLEKAGLDMERI 178
Query: 181 LKKLQSSFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEG 240
+KL+SSFKSAEFE++GYT+I+RPKK KIS LRRLAEKVKKHRLKGLS VGKT++ K+
Sbjct: 179 QRKLESSFKSAEFEVDGYTVIMRPKKVGKISSLRRLAEKVKKHRLKGLSRVGKTVITKDS 238
Query: 241 --DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQ 298
EY+I TEGSNFKQVLKVPGVDPTRT+TN+I EIAEVLGIEAARNAII+EI+ TM EQ
Sbjct: 239 KTGEYIIRTEGSNFKQVLKVPGVDPTRTRTNDIREIAEVLGIEAARNAIIDEILKTMEEQ 298
Query: 299 GLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVD 358
GLEVD+RHIMLVAD+MTLDGV+RPIGRHG+VGEKASVLARAAFEIT QHLFEAAERG VD
Sbjct: 299 GLEVDVRHIMLVADMMTLDGVIRPIGRHGIVGEKASVLARAAFEITTQHLFEAAERGAVD 358
Query: 359 NLSGVIENVLIGQPVPVGTGMVKLTMKLPLRPQKE 393
L+GV+ENVLIGQPVPVGTG VKL M LPLRP++E
Sbjct: 359 PLNGVVENVLIGQPVPVGTGTVKLAMNLPLRPKRE 393
>gb|AAK40565.1| DNA-directed RNA polymerase, subunit A'' (rpoA2) [Sulfolobus
solfataricus]
Length = 395
Score = 397 bits (1008), Expect = e-109
Identities = 199/387 (51%), Positives = 278/387 (71%), Gaps = 6/387 (1%)
Query: 8 KSLIEKKGKDLPESVKQELYEKL--IKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEA 65
K +E+K K + Q++ + L + N++ +T+ E++ I D +KEY L+ PGEA
Sbjct: 10 KPYLEEKVKQASNILPQKIVDDLKNLILNKEIIVTRDEIDKIFDLAIKEYSEGLIAPGEA 69
Query: 66 VGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEE 125
+G VAAQS+GEP TQMTL TFH+AG+ E+NVTLGLPR+IEIVDA+K PSTPMMT+YL +E
Sbjct: 70 IGIVAAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTPMMTIYLTDE 129
Query: 126 HRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQ 185
++ DR+KA EVAR++E T +EN+ +T++D+ +M I+++D E L+ G+T++ V KK
Sbjct: 130 YKRDRDKALEVARKLEYTKIENVVSSTSIDIASMSIILQLDNEMLKDKGVTVDDV-KKAI 188
Query: 186 SSFKSAEF---EMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDE 242
K +F E E TL + + I+ L +L +K+ ++KG+ G+ + IV+K+GDE
Sbjct: 189 GRLKLGDFMIEESEDSTLNINFANIDSIAALFKLRDKILNTKIKGIKGIKRAIVQKKGDE 248
Query: 243 YVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEV 302
Y+I T+GSN VL V GVD + +TNNI EI EV GIEAAR II EI + EQGL+V
Sbjct: 249 YIILTDGSNLSGVLSVKGVDVAKVETNNIREIEEVFGIEAAREIIIREISKVLAEQGLDV 308
Query: 303 DIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSG 362
DIRHI+L+AD+MT G+VR IGRHGV GEK SVLARAAFE+TV+HL +AA RG+V+ G
Sbjct: 309 DIRHILLIADVMTRTGIVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAARGDVEEFKG 368
Query: 363 VIENVLIGQPVPVGTGMVKLTMKLPLR 389
V+EN++IG P+ +GTGMV+LTM+ LR
Sbjct: 369 VVENIIIGHPIKLGTGMVELTMRPILR 395
>sp|P14247|RPA2_METVA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|629377|pir||S47163
DNA-directed RNA polymerase (EC 2.7.7.6) - Methanococcus
vannielii >gi|505293|emb|CAA51729.1| (X73293)
DNA-directed RNA polymerase [Methanococcus vannielii]
Length = 386
Score = 387 bits (984), Expect = e-106
Identities = 200/387 (51%), Positives = 280/387 (71%), Gaps = 11/387 (2%)
Query: 11 IEKKGKD--LPESVKQELYEKLIK--YNEKYKLTKAEVETIIDEVVKEYERALVEPGEAV 66
+EKK ++ LP +++EL EK++K NE+Y V+ II E ++ Y R ++EPGEAV
Sbjct: 6 LEKKLENSVLPPLLRRELSEKILKENINEEYI-----VDEIIQETIRAYSRTVIEPGEAV 60
Query: 67 GTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEH 126
G +AAQSIGEP TQMT+ TFHYAGVAE+NVTLGLPR+IEIVDARK PSTP M++YL ++
Sbjct: 61 GVIAAQSIGEPGTQMTMRTFHYAGVAELNVTLGLPRMIEIVDARKEPSTPTMSIYLRGDY 120
Query: 127 RYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQS 186
+YDRE A V++ IE TT+E+++ ++DL+N + +D ++LE LT+ V++ ++S
Sbjct: 121 KYDRESAAIVSKNIESTTVESVSEDISVDLVNECITIVLDVQQLESRQLTVNNVVEAIKS 180
Query: 187 SFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIY 246
K E E ++ K + LR+ KV++ LKG+ + + I+RKE DEYV+Y
Sbjct: 181 KMKLKIEENEN--ILSLKIKTPSLKALRKRLPKVREIHLKGVPNIKRVIIRKEIDEYVLY 238
Query: 247 TEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRH 306
+EGSN K+V ++ GVD T+T TNNI EI +VLG+EAARNAII E+ T+ QGL VD RH
Sbjct: 239 SEGSNLKEVFEIDGVDTTKTTTNNIVEIQDVLGVEAARNAIIREMDATLGNQGLTVDKRH 298
Query: 307 IMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIEN 366
+M+VAD+MT DGVV+PIGRHG+ GEKASVLARAAFE TV+HL+ A+ RG VD+LSGV+EN
Sbjct: 299 LMMVADLMTTDGVVKPIGRHGIGGEKASVLARAAFEETVKHLYSASMRGYVDDLSGVVEN 358
Query: 367 VLIGQPVPVGTGMVKLTMKLPLRPQKE 393
+++G+P+ +GTG + + +K KE
Sbjct: 359 IIVGKPISMGTGCINVCIKKEYEEGKE 385
>sp|P11514|RPA2_SULAC DNA-DIRECTED RNA POLYMERASE SUBUNIT A" (SUBUNIT C)
>gi|81109|pir||S04718 DNA-directed RNA polymerase (EC
2.7.7.6) chain C [validated] - Sulfolobus acidocaldarius
>gi|46671|emb|CAA32926.1| (X14818) RNA polymerase
subunit C (AA 1-392) [Sulfolobus acidocaldarius]
Length = 392
Score = 386 bits (980), Expect = e-106
Identities = 194/389 (49%), Positives = 281/389 (71%), Gaps = 8/389 (2%)
Query: 7 IKSLIEKKGKDLPESVKQELYEKL---IKYNEKYKLTKAEVETIIDEVVKEYERALVEPG 63
+K I+K+ ++ + + +L+E L I +LT+ +++ IID ++EY+++L+EPG
Sbjct: 6 LKGYIDKRLNEIKDKIPDKLHEDLRAAIMDINGVELTEEDIDRIIDLTIREYQQSLIEPG 65
Query: 64 EAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLD 123
EA+G V AQS+GEP TQMTL TFH+AG+ E+NVTLGLPR+IEIVDARK PSTPMMT+YL
Sbjct: 66 EAIGVVTAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDARKVPSTPMMTIYLT 125
Query: 124 EEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKK 183
+E++ D++KA ++ARRIE T +EN+ + ++D+ NM ++ D E L+ G+++E++ KK
Sbjct: 126 DEYKTDKDKALDIARRIEYTRVENVVSSVSVDISNMSITLQFDQEMLKDKGVSIEEI-KK 184
Query: 184 LQSSFKSAEFEMEG---YTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEG 240
+ + K E +E Y+ + +K + I L ++ EK+ KG G + IV+K+G
Sbjct: 185 IITKLKLGEIRIEDNDEYSFTIYFEKIDSIMALFKMREKILIQD-KGSQGYKRAIVQKKG 243
Query: 241 DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGL 300
DEYVI T+GSN + ++ V GVD + +TNNIHE+ EVLG+EAAR I EI + EQGL
Sbjct: 244 DEYVIITDGSNLEGIMNVTGVDINKIQTNNIHEVEEVLGMEAARELISREIKKVLEEQGL 303
Query: 301 EVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNL 360
+VD+RHI+LV+DIMT G +R IGRHGV GEK+SVLARAAFE+TV+HL +AA RGE +
Sbjct: 304 DVDMRHIVLVSDIMTRTGDIRQIGRHGVTGEKSSVLARAAFEVTVKHLLDAAARGEREEF 363
Query: 361 SGVIENVLIGQPVPVGTGMVKLTMKLPLR 389
GVIEN++IGQP+ +GTG+V+LTMK +R
Sbjct: 364 KGVIENIIIGQPIRLGTGIVELTMKPNMR 392
>sp|O27126|RPA2_METTH DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|7434725|pir||H69006
DNA-directed RNA polymerase (EC 2.7.7.6) chain A'' -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2622151|gb|AAB85543.1| (AE000876) DNA-dependent RNA
polymerase, subunit A'' [Methanobacterium
thermoautotrophicum]
Length = 451
Score = 385 bits (979), Expect = e-106
Identities = 197/379 (51%), Positives = 272/379 (70%), Gaps = 7/379 (1%)
Query: 7 IKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAV 66
++ L+++K P + +++ E + +K++L+ E++ +I V + Y+RA VE GEAV
Sbjct: 77 VQELVKRKRARFPPKLIEDIAEVM----KKHELSDDELDELIRRVRRAYDRARVEAGEAV 132
Query: 67 GTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEH 126
GTVAAQS+GEP TQMT+ TFHYAGVAE+NVTLGLPR+IEIVDARK STP M++Y + +
Sbjct: 133 GTVAAQSVGEPGTQMTMRTFHYAGVAELNVTLGLPRLIEIVDARKKISTPTMSIYFEGDL 192
Query: 127 RYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQS 186
RYD E A +I +TL ++ + ++ +M + E+D E++++ L +++L K++
Sbjct: 193 RYDEEFVRRKANKIGKSTLNDVLKNFSIQYADMSVVAELDEEKIQEKHLEYDEILAKVEK 252
Query: 187 SFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIY 246
+FK E ++ L P K I +LR LA+KV+K ++ G+ +GK ++RKE DE+VI+
Sbjct: 253 TFKKVE--IDNNILRFEPPK-PTIRELRLLADKVRKLQISGVKNIGKVVIRKEDDEWVIH 309
Query: 247 TEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRH 306
TEGSN VLK GVD RT TN+IHEI VLGIEAARNAII E TM EQGL VDIRH
Sbjct: 310 TEGSNLGAVLKEEGVDKVRTTTNDIHEIETVLGIEAARNAIIHEAKRTMEEQGLTVDIRH 369
Query: 307 IMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIEN 366
IMLVAD+MT DG V+ IGRHG+ GEKASVLARA+FE T +HL A+ RGEVD+L+G+IEN
Sbjct: 370 IMLVADMMTADGSVKSIGRHGISGEKASVLARASFEETGKHLLRASIRGEVDHLTGIIEN 429
Query: 367 VLIGQPVPVGTGMVKLTMK 385
++IGQP+P+GTG V + MK
Sbjct: 430 IIIGQPIPLGTGSVSVVMK 448
>gi|11499473 DNA-directed RNA polymerase, subunit A'' (rpoA2) [Archaeoglobus
fulgidus] >gi|7434726|pir||H69485 DNA-directed RNA
polymerase, subunit A'' (rpoA2) homolog - Archaeoglobus
fulgidus >gi|2648655|gb|AAB89364.1| (AE000972)
DNA-directed RNA polymerase, subunit A'' (rpoA2)
[Archaeoglobus fulgidus]
Length = 380
Score = 382 bits (970), Expect = e-105
Identities = 201/369 (54%), Positives = 267/369 (71%), Gaps = 9/369 (2%)
Query: 19 PESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPS 78
P +VK+E+ +L EK+ L K E + ++++ + Y L+EPGEA G VAAQSIGEP
Sbjct: 16 PPAVKEEIKAEL----EKHGLKKTEAKKVVEKCFQAYLANLMEPGEAAGIVAAQSIGEPG 71
Query: 79 TQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVAR 138
TQMT+ TFHYAGVAEINVTLGLPR+IEI+D RKNPSTPMMT+ L E+ DREKA EVA
Sbjct: 72 TQMTMRTFHYAGVAEINVTLGLPRLIEILDVRKNPSTPMMTIRLLPEYAKDREKAREVAN 131
Query: 139 RIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQSSFKSAEFEME-G 197
RIE T ++++A +D+ IV+ D + LE+ GLT+E + K+ + K+ E E G
Sbjct: 132 RIEATYVKDVA-DIEVDIRRFTIIVKPDEKALERKGLTVEDLKSKIGKALKTEVEETEQG 190
Query: 198 YTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIYTEGSNFKQVLK 257
+ + ++ L +K+K + GL + + I+RKE DEYV+YTEGSN K+++K
Sbjct: 191 LAVQITEPSYKA---LMAAFDKLKDTVIMGLKEIKRVIIRKEEDEYVLYTEGSNLKKIMK 247
Query: 258 VPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLD 317
V GVD TRT TNNI+EI EVLGIEAARNAII E ++T+ EQGLEVD+RHIMLVAD+MT D
Sbjct: 248 VKGVDFTRTTTNNIYEIYEVLGIEAARNAIIREALDTLEEQGLEVDVRHIMLVADVMTAD 307
Query: 318 GVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGT 377
G +R IGRHGV GEK S+LARAAFE+TV +L +AA RGE D+L G+ EN+++GQP+ +GT
Sbjct: 308 GELRQIGRHGVAGEKQSILARAAFEMTVNNLLDAAVRGEEDHLRGITENIIVGQPIKLGT 367
Query: 378 GMVKLTMKL 386
G V+L +K+
Sbjct: 368 GDVELVLKM 376
>sp|P09847|RPA2_METTW DNA-DIRECTED RNA POLYMERASE SUBUNIT A" (SUBUNIT C)
>gi|80921|pir||S02197 DNA-directed RNA polymerase (EC
2.7.7.6) chain A'' - Methanobacterium
thermoautotrophicum (strain Winter)
>gi|809728|emb|CAA30839.1| (X08038) RNA polymerase
subunit C (AA 1-449) [Methanobacterium
thermoautotrophicum]
Length = 449
Score = 377 bits (958), Expect = e-103
Identities = 193/379 (50%), Positives = 268/379 (69%), Gaps = 7/379 (1%)
Query: 7 IKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAV 66
++ L+++K P + +E+ E + +++ L+ E++ ++ V + YERA+VE GEAV
Sbjct: 77 VRELVKRKRAKFPPRLIEEIAEAI----KRHGLSDDELDELVRGVRRAYERAMVEAGEAV 132
Query: 67 GTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEH 126
GTVAAQS+GEP TQMT+ TFHYAGVAE+NVTLGLPR+IEIVDARK STP M++Y + +
Sbjct: 133 GTVAAQSVGEPGTQMTMRTFHYAGVAELNVTLGLPRLIEIVDARKKISTPTMSIYFEGDR 192
Query: 127 RYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQS 186
+YD E + A +I +TL ++ + ++ +M E+D E++ + L + ++ K++
Sbjct: 193 KYDEEFVRKKANKICKSTLNDVLKNFSIQYADMSVEAELDEEKIREKHLEYDDIIAKVEK 252
Query: 187 SFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIY 246
+FK E ++ L P K I +LR LA+KV+K ++ G+ +GK ++RKE DE+VI+
Sbjct: 253 TFKKVE--IDNNILRFEPPK-PTIRELRLLADKVRKLQISGVKNIGKVVIRKEDDEWVIH 309
Query: 247 TEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRH 306
TEGSN K GVD RT TN+IHEI VLGIEAARNAII E TM EQGL VDIRH
Sbjct: 310 TEGSNLGDRFKEEGVDKVRTTTNDIHEIETVLGIEAARNAIIHEAKRTMEEQGLTVDIRH 369
Query: 307 IMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIEN 366
IMLVAD+MT DG V+ IGRHG+ GEKASVLARA+FE T +HL A+ RGEVD+L+G+IEN
Sbjct: 370 IMLVADMMTADGSVKSIGRHGISGEKASVLARASFEETGKHLLRASIRGEVDHLTGIIEN 429
Query: 367 VLIGQPVPVGTGMVKLTMK 385
++IGQP+P+GTG V + MK
Sbjct: 430 IIIGQPIPLGTGSVSVIMK 448
>sp|Q58446|RPA2_METJA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|2127865|pir||B64430
DNA-directed RNA polymerase (EC 2.7.7.6) subunit A''
(intein-containing) - Methanococcus jannaschii
>gi|1591697|gb|AAB99047.1| (U67547) DNA-directed RNA
polymerase, subunit A'' (rpoA2) [Methanococcus
jannaschii]
Length = 859
Score = 367 bits (933), Expect = e-101
Identities = 198/372 (53%), Positives = 260/372 (69%), Gaps = 7/372 (1%)
Query: 30 LIKYNEKYKLTKA-EVETIIDEVVKEYE----RALVEPGEAVGTVAAQSIGEPSTQMTLN 84
++ E + L KA E + I DE+VK E + V G + T T+
Sbjct: 490 ILALKEYWLLKKAVESDVIWDEIVKIEEISCDKKYVYDISVEGLETFTTFDGVLTHNTMR 549
Query: 85 TFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTT 144
TFHYAGVAEINVTLGLPR+IEIVDARK PSTP+MT+YL EE++ +REKAEE+A+ IE T
Sbjct: 550 TFHYAGVAEINVTLGLPRMIEIVDARKEPSTPIMTIYLKEEYKDNREKAEEIAKEIESLT 609
Query: 145 LENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQSSFKSAEFEMEGYTLIVRP 204
L ++A + ++DL VE+D RL GLT++ V++ ++ K + +++G TL ++
Sbjct: 610 LGSIAESISIDLWTQSIKVELDENRLADRGLTIDDVIEAIKKKLK-VKIDVDGTTLYLKI 668
Query: 205 KKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIYTEGSNFKQVLKVPGVDPT 264
K I LR+ K+K +LKG+ G+ + +V+KEG EYV+YT+GSN ++V K+ GVD T
Sbjct: 669 KT-PSIKALRKRIPKIKNIQLKGIPGIERVLVKKEGGEYVLYTQGSNLREVFKIDGVDTT 727
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT TNNI EI EVLGIEAARNAII E+ NT+ +QGLEVDIRH+MLVADIMT DG V+PIG
Sbjct: 728 RTITNNIIEIQEVLGIEAARNAIINEMRNTLEQQGLEVDIRHLMLVADIMTADGEVKPIG 787
Query: 325 RHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
RHGV GEK SVLARAAFE TV+HL+ AAERG+VD L GVIENV++G+P+ +GTG V+LT+
Sbjct: 788 RHGVAGEKGSVLARAAFEETVKHLYAAAERGDVDKLKGVIENVIVGKPIYLGTGCVELTI 847
Query: 385 KLPLRPQKEKEE 396
K EE
Sbjct: 848 DREYEEGKNMEE 859
Score = 80.8 bits (196), Expect = 2e-14
Identities = 43/70 (61%), Positives = 53/70 (75%), Gaps = 3/70 (4%)
Query: 14 KGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQS 73
+G D+P+S+K EL+EKL K + LT+ V+ IIDEVV Y +ALVEP EAVG VAAQS
Sbjct: 11 EGLDIPQSLKDELFEKLSKEKD---LTEEMVDEIIDEVVNAYRKALVEPYEAVGIVAAQS 67
Query: 74 IGEPSTQMTL 83
IGEP TQM+L
Sbjct: 68 IGEPGTQMSL 77
>pir||C33926 DNA-directed RNA polymerase (EC 2.7.7.6) C - Sulfolobus
acidocaldarius
Length = 381
Score = 361 bits (916), Expect = 9e-99
Identities = 187/387 (48%), Positives = 267/387 (68%), Gaps = 26/387 (6%)
Query: 7 IKSLIEKKGKDLPESVKQELYEKL---IKYNEKYKLTKAEVETIIDEVVKEYERALVEPG 63
+K I+K+ ++ + + +L+E L I +LT+ +++ IID ++EY+++L+EPG
Sbjct: 6 LKGYIDKRLNEIKDKIPDKLHEDLRAAIMDINGVELTEEDIDRIIDLTIREYQQSLIEPG 65
Query: 64 EAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLD 123
EA+G V AQS+GEP TQMTL TFH+AG+ E+NVTLGLPR+IEIVDARK PSTPMMT+YL
Sbjct: 66 EAIGVVTAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDARKVPSTPMMTIYLT 125
Query: 124 EEHRYDREKAEEVARRIEGTTLENLAR---------TTTLDLINMEFIVEIDPERLEKSG 174
+E++ D++KA ++ARRIE T +EN+ T +D+ NM ++ D E L+ G
Sbjct: 126 DEYKTDKDKALDIARRIEYTRVENVVSSVSEIKKIITKLVDISNMSITLQFDQEMLKDKG 185
Query: 175 LTMEKVLKKLQSSFKSAEFEMEG---YTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGV 231
+++EK+ E +E Y+ + +K + I+ L ++ EK+ KG G
Sbjct: 186 VSIEKL----------GEIRIEDNDEYSFTIYFEKIDSINALFKMREKILIQD-KGSQGY 234
Query: 232 GKTIVRKEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEI 291
+ IV+K+GDEYVI T+GSN + ++ V GVD + +TNNIHE+ EVLG+EAAR I EI
Sbjct: 235 KRAIVQKKGDEYVIITDGSNLEGIMNVTGVDINKIQTNNIHEVEEVLGMEAARELISREI 294
Query: 292 MNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEA 351
+ EQGL+VD+RHI+LV+DIMT G +R IGRHGV GEK+SVLARAAFE+TV+HL +A
Sbjct: 295 KKVLEEQGLDVDMRHIVLVSDIMTRTGDIRQIGRHGVTGEKSSVLARAAFEVTVKHLLDA 354
Query: 352 AERGEVDNLSGVIENVLIGQPVPVGTG 378
A RGE + GVIEN++IGQP+ +GTG
Sbjct: 355 AARGEREEFKGVIENIIIGQPIRLGTG 381
>sp|P15353|RPA2_HALMO DNA-DIRECTED RNA POLYMERASE SUBUNIT A" (SUBUNIT C)
>gi|81081|pir||S03576 DNA-directed RNA polymerase (EC
2.7.7.6) chain C - Halococcus morrhuae
>gi|43622|emb|CAA40432.1| (X57145) C subunit [Halococcus
morrhuae]
Length = 393
Score = 340 bits (864), Expect = 1e-92
Identities = 188/385 (48%), Positives = 258/385 (66%), Gaps = 14/385 (3%)
Query: 7 IKSLIEK--KGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGE 64
I + IE+ +G DLP+ +K E+YE + E +T + +I + V Y VEP +
Sbjct: 4 ITNAIERTVEGTDLPKRLKDEVYESI----EGRDVTDEQAVSIAEAVESRYLDTRVEPLD 59
Query: 65 AVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDE 124
VGTV+AQSIGEP TQMT+NTFHYAGVAEI+VT GLPR+IE+VDARK P TPMMTVYLD+
Sbjct: 60 PVGTVSAQSIGEPGTQMTMNTFHYAGVAEIDVTQGLPRLIELVDARKTPDTPMMTVYLDD 119
Query: 125 EHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKL 184
+H +REKA EV IE T + L +T ++ +M V ++ + L++ ++ E V + +
Sbjct: 120 QHAENREKAHEVVWNIESTRILALGDVST-NVADMLVQVNLNEQTLDERMISAETVAEII 178
Query: 185 QSSFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKE----G 240
+ S E G T+ P + L +L E++++ KG+ V + ++RKE G
Sbjct: 179 EDSL-GVEVTQTGTTIEFGPAE-PSYRRLLQLVEELREIVFKGIEEVSRVVIRKEDVDDG 236
Query: 241 DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGL 300
+E+++YTEGS F VL + GVD +RT NNIHE+ LG+EAAR II+E MNT+ EQGL
Sbjct: 237 EEFILYTEGSAFGDVLDIEGVDASRTTCNNIHEVYRNLGVEAARETIIDETMNTLEEQGL 296
Query: 301 -EVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDN 359
+V+IRH+MLVADIMT +G + IGRHG+ G K SVLARAAFE+TV HL +AA GEVD+
Sbjct: 297 GDVNIRHLMLVADIMTAEGTIESIGRHGISGNKNSVLARAAFEVTVNHLLDAAVHGEVDD 356
Query: 360 LSGVIENVLIGQPVPVGTGMVKLTM 384
L GV ENV++G+P+ +GTG V L M
Sbjct: 357 LDGVTENVIVGKPIKLGTGDVNLRM 381
>sp|Q03586|RPA2_THEAC DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|280356|pir||S26724
DNA-directed RNA polymerase (EC 2.7.7.6) chain A'' -
Thermoplasma acidophilum >gi|48093|emb|CAA48282.1|
(X68198) DNA-directed RNA polymerase [Thermoplasma
acidophilum]
Length = 508
Score = 337 bits (854), Expect = 2e-91
Identities = 181/373 (48%), Positives = 250/373 (66%), Gaps = 11/373 (2%)
Query: 15 GKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSI 74
G LPESV +E+ + ++ EK + I+ + +E L++P EAVG +AAQSI
Sbjct: 138 GFTLPESVAEEIARRRTEWGEK------AYKNILKRIGEEIGNELIDPYEAVGIIAAQSI 191
Query: 75 GEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAE 134
GEP TQMT+ TFH+AGV E+NVTLGLPR+IEIVDAR+ PSTP MT+YL E+ + E
Sbjct: 192 GEPGTQMTMRTFHFAGVREMNVTLGLPRLIEIVDARRIPSTPSMTIYLRPEYETNDEVVM 251
Query: 135 EVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQSSFKSAEFE 194
+V +R+E T++ ++A T D+ + V DP + + + ME ++ + S K
Sbjct: 252 DVVKRLENTSISDVADIIT-DIGELTVTVRPDPRKTKDRLIEMEDIMNAI-SKIKGITVM 309
Query: 195 MEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEY--VIYTEGSNF 252
+ +I++P++ E L L E++K +KG+SG+ + I R EG E+ VIYT+GSN
Sbjct: 310 EDSGQIIIKPQQ-ESFKKLYLLQEQIKGLTIKGISGIKRAIARVEGKEHRWVIYTQGSNL 368
Query: 253 KQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVAD 312
K VL+V VDPTRT TN+I EIA VLGIEAARNAI+ E + T++EQGL VD+RH+MLVAD
Sbjct: 369 KDVLEVDEVDPTRTYTNDIVEIANVLGIEAARNAILNEALRTLQEQGLNVDVRHLMLVAD 428
Query: 313 IMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQP 372
+MT G VR +GR G+ G K+SVLARAAFEIT +HL A GEVD L+GV EN+++GQP
Sbjct: 429 MMTFSGSVRAVGRTGISGRKSSVLARAAFEITTKHLLRAGIMGEVDKLAGVAENIIVGQP 488
Query: 373 VPVGTGMVKLTMK 385
+ +GTG V + K
Sbjct: 489 ITLGTGAVDIIYK 501
>emb|CAC11536.1| (AL445064) probable DNA-directed RNA polymerase, chain A
[Thermoplasma acidophilum]
Length = 511
Score = 337 bits (854), Expect = 2e-91
Identities = 181/373 (48%), Positives = 250/373 (66%), Gaps = 11/373 (2%)
Query: 15 GKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSI 74
G LPESV +E+ + ++ EK + I+ + +E L++P EAVG +AAQSI
Sbjct: 141 GFTLPESVAEEIARRRTEWGEK------AYKNILKRIGEEIGNELIDPYEAVGIIAAQSI 194
Query: 75 GEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAE 134
GEP TQMT+ TFH+AGV E+NVTLGLPR+IEIVDAR+ PSTP MT+YL E+ + E
Sbjct: 195 GEPGTQMTMRTFHFAGVREMNVTLGLPRLIEIVDARRIPSTPSMTIYLRPEYETNDEVVM 254
Query: 135 EVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQSSFKSAEFE 194
+V +R+E T++ ++A T D+ + V DP + + + ME ++ + S K
Sbjct: 255 DVVKRLENTSISDVADIIT-DIGELTVTVRPDPRKTKDRLIEMEDIMNAI-SKIKGITVM 312
Query: 195 MEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEY--VIYTEGSNF 252
+ +I++P++ E L L E++K +KG+SG+ + I R EG E+ VIYT+GSN
Sbjct: 313 EDSGQIIIKPQQ-ESFKKLYLLQEQIKGLTIKGISGIKRAIARVEGKEHRWVIYTQGSNL 371
Query: 253 KQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVAD 312
K VL+V VDPTRT TN+I EIA VLGIEAARNAI+ E + T++EQGL VD+RH+MLVAD
Sbjct: 372 KDVLEVDEVDPTRTYTNDIVEIANVLGIEAARNAILNEALRTLQEQGLNVDVRHLMLVAD 431
Query: 313 IMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQP 372
+MT G VR +GR G+ G K+SVLARAAFEIT +HL A GEVD L+GV EN+++GQP
Sbjct: 432 MMTFSGSVRAVGRTGISGRKSSVLARAAFEITTKHLLRAGIMGEVDKLAGVAENIIVGQP 491
Query: 373 VPVGTGMVKLTMK 385
+ +GTG V + K
Sbjct: 492 ITLGTGAVDIIYK 504
>pir||C72571 probable DNA-directed RNA polymerase subunit A APE1852 - Aeropyrum
pernix (strain K1) >gi|5105543|dbj|BAA80856.1|
(AP000062) 410aa long hypothetical DNA-directed RNA
polymerase subunit A [Aeropyrum pernix]
Length = 410
Score = 326 bits (828), Expect = 2e-88
Identities = 190/401 (47%), Positives = 264/401 (65%), Gaps = 26/401 (6%)
Query: 6 TIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEA 65
T++ +E LPES+ +EL E + K + L++ + +++ E ++ Y R+L +PGEA
Sbjct: 9 TLEESLEAARYILPESLYKELVETVEKEDG---LSEEDKISVVKETIRTYLRSLAQPGEA 65
Query: 66 VGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEE 125
VGTVAAQSIGEP TQMTL TFHYAG+ E +VTLGLPR+IEIVDA++ PS P+M +YL +E
Sbjct: 66 VGTVAAQSIGEPGTQMTLRTFHYAGIMEFDVTLGLPRLIEIVDAKQTPSQPLMYIYLKDE 125
Query: 126 HRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQ 185
+ D EKA+E AR+IE TTLE + DL + + I+ E +E G+T++ VL+ L
Sbjct: 126 YAKDLEKAKEAARKIEYTTLEKIIDNIEWDLGDRVVAIVINAEYMEDKGVTVDMVLEALD 185
Query: 186 SSFKSAEFEMEGYTLIVRP--KK---FEKISDLR-------------RLAEKVKKHRLKG 227
S K + +G + KK + +ISD + ++ EK+K +KG
Sbjct: 186 KS-KLGKVVEDGVREVSEGGVKKVIVYFEISDKQLPDEELFNSNAYHKVLEKLKNTYIKG 244
Query: 228 LSGVGK-TIVRKEGD---EYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAA 283
+ G+ K T+ R+EG+ EY++ EGSN ++VL +P VD R+ +N+I EIA+VLGIEAA
Sbjct: 245 IKGIRKVTVRREEGEDSYEYMLIVEGSNLREVLMLPEVDHRRSISNDIQEIAQVLGIEAA 304
Query: 284 RNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEI 343
R AIIEEI + + GL+VDIRH+ML+AD+MT G VR IGR GVVGEK S LARAAFE+
Sbjct: 305 RTAIIEEIKRVLEDSGLDVDIRHLMLIADLMTWPGYVRQIGRLGVVGEKPSPLARAAFEV 364
Query: 344 TVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
TV+ L+EAA GE + +GV EN++ G P VGTG V L M
Sbjct: 365 TVKQLYEAAVWGEEEEFAGVTENIIAGLPPRVGTGSVLLRM 405
>emb|CAA42846.1| (X60305) subunit A'' of RNA polymerase [Thermococcus celer]
Length = 199
Score = 323 bits (819), Expect = 2e-87
Identities = 162/199 (81%), Positives = 180/199 (90%), Gaps = 2/199 (1%)
Query: 197 GYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGD--EYVIYTEGSNFKQ 254
GYT+I+RPKK KIS LRRLAEKVKKHRLKGLS VGKT++ K+ EY+I TEGSNFKQ
Sbjct: 1 GYTVIMRPKKVGKISSLRRLAEKVKKHRLKGLSRVGKTVITKDSKTGEYIIRTEGSNFKQ 60
Query: 255 VLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIM 314
VLKVPGVDPTRT+TN+I EIAEVLGIEAARNAII+EI+ TM EQGLEVD+RHIMLVAD+M
Sbjct: 61 VLKVPGVDPTRTRTNDIREIAEVLGIEAARNAIIDEILKTMEEQGLEVDVRHIMLVADMM 120
Query: 315 TLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVP 374
TLDGV+RPIGRHG+VGEKASVLARAAFEIT QHLFEAAERG VD L+GV+ENVLIGQPVP
Sbjct: 121 TLDGVIRPIGRHGIVGEKASVLARAAFEITTQHLFEAAERGAVDPLNGVVENVLIGQPVP 180
Query: 375 VGTGMVKLTMKLPLRPQKE 393
VGTG VKL M LPLRP++E
Sbjct: 181 VGTGTVKLAMNLPLRPKRE 199
>sp|P15354|RPA2_HALHA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" (SUBUNIT C)
>gi|81036|pir||S03577 DNA-directed RNA polymerase (EC
2.7.7.6) chain C - Halobacterium salinarum
>gi|43543|emb|CAA40427.1| (X57144) RNA polymerase
subunit C [Halobacterium halobium]
>gi|10582042|gb|AAG20691.1| (AE005138) DNA-directed RNA
polymerase subunit C; RpoC [Halobacterium sp. NRC-1]
Length = 397
Score = 319 bits (808), Expect = 4e-86
Identities = 177/379 (46%), Positives = 251/379 (65%), Gaps = 17/379 (4%)
Query: 17 DLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGE 76
+LP +K E+ + E+ +TK++ I V +Y V+P + VGTV+AQSIGE
Sbjct: 18 ELPRRLKDEV----LATAEERGVTKSQANEIATAVEAQYLDTRVDPLDPVGTVSAQSIGE 73
Query: 77 PSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEV 136
P TQMT+NTFHYAGVAE++VT GLPR+IE+VDARK P TP+M VYL++E+ +RE+A EV
Sbjct: 74 PGTQMTMNTFHYAGVAEMDVTQGLPRLIELVDARKTPDTPVMEVYLEDEYAEERERAHEV 133
Query: 137 ARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQSSFKSAEFEM- 195
+IE T + L +T ++ +M ++++ + L++ ++ + ++ E +
Sbjct: 134 VWKIEATKILALGDIST-NVADMVVRIDLNEDTLQERWPRVDSTTQIAGEVAETIEGNLG 192
Query: 196 -----EGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKE----GDEYVIY 246
+G L P + +L +L E+++ KG+ V + ++R+E G+E+V+Y
Sbjct: 193 VTVTQDGTILEFGPSE-PSYRELLQLVEQLRDIVFKGIEEVSRVVIRREETERGEEFVLY 251
Query: 247 TEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGL-EVDIR 305
TEGS FK+ LK+ GVD TRT NNIHE+ + LGIEAAR AII E M T+ EQGL +V+IR
Sbjct: 252 TEGSAFKKALKIEGVDATRTSCNNIHEVHKTLGIEAAREAIINETMTTLEEQGLDDVNIR 311
Query: 306 HIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIE 365
H+MLVADIMT DG + IGRHG+ G K SVLARAAFE+TV HL +AA GE D+L GVIE
Sbjct: 312 HLMLVADIMTNDGTIESIGRHGISGNKNSVLARAAFEVTVNHLLDAAIHGESDDLDGVIE 371
Query: 366 NVLIGQPVPVGTGMVKLTM 384
NV++G+PV +GTG V L M
Sbjct: 372 NVIVGKPVRLGTGDVDLRM 390
>pir||D33926 DNA-directed RNA polymerase (EC 2.7.7.6) chain C - Halobacterium
halobium (fragment)
Length = 365
Score = 302 bits (766), Expect = 4e-81
Identities = 173/367 (47%), Positives = 236/367 (64%), Gaps = 24/367 (6%)
Query: 17 DLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGE 76
+LP +K E+ + E+ +TK++ I V +Y V+P + VGTV+AQSIGE
Sbjct: 18 ELPRRIKDEV----LATAEERGVTKSQANEIATAVEAQYLDTRVDPLDPVGTVSAQSIGE 73
Query: 77 PSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEV 136
P TQMT+NTFHYAGVAE++V LPR+IE+VDARK P TP+M VYL++E+ +RE+A EV
Sbjct: 74 PGTQMTMNTFHYAGVAEMDV---LPRLIELVDARKTPDTPVMEVYLEDEYAEERERAHEV 130
Query: 137 ARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKKLQSSFKSAEFEME 196
+IE T + L +T N +V ID L + + ++ +
Sbjct: 131 VWKIEATKILALGDISTNVADN---VVRID--------LNEDTLQERWIEGNLGVTVTQD 179
Query: 197 GYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKE----GDEYVIYTEGSNF 252
G L P + +L +L E+++ KG+ V + ++R+E G+E+V+YTEGS F
Sbjct: 180 GTILEFGPSE-PSYRELLQLVEQLRDIVFKGIEEVSRVVIRREETERGEEFVLYTEGSAF 238
Query: 253 KQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLE-VDIRHIMLVA 311
K+ LK+ GVD TRT NNIHE+ + LGIEAAR AII E M T+ EQGL+ V+IRH+MLVA
Sbjct: 239 KKALKIEGVDATRTSCNNIHEVHKTLGIEAAREAIINETMTTLEEQGLDDVNIRHLMLVA 298
Query: 312 DIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQ 371
DI T DG + IGRHG+ G K SVLARAAFE+TV HL +AA GE D+L GVIENV++G+
Sbjct: 299 DINTNDGTIESIGRHGISGNKNSVLARAAFEVTVNHLLDAAIHGESDDLDGVIENVIVGK 358
Query: 372 PVPVGTG 378
PV +GTG
Sbjct: 359 PVRLGTG 365
>gi|6320061 RNA polymerase II large subunit; Rpo21p [Saccharomyces cerevisiae]
>gi|2507347|sp|P04050|RPB1_YEAST DNA-DIRECTED RNA
POLYMERASE II LARGEST SUBUNIT (B220)
>gi|2144431|pir||RNBY2L DNA-directed RNA polymerase (EC
2.7.7.6) II 215K chain - yeast (Saccharomyces cerevisiae)
>gi|1419221|emb|CAA65619.1| (X96876) RPB1 [Saccharomyces
cerevisiae] >gi|1431217|emb|CAA98713.1| (Z74188) ORF
YDL140c [Saccharomyces cerevisiae]
Length = 1733
Score = 234 bits (590), Expect = 2e-60
Identities = 142/407 (34%), Positives = 225/407 (54%), Gaps = 63/407 (15%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++Y+LTK + ++ + ++ R++V PGE VG +AAQSIGEP+TQMTLNTFH+AGVA
Sbjct: 1033 QEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASK 1092
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLA----- 149
VT G+PR+ EI++ KN TP +TVYL+ H D+E+A+ + IE TTL+++
Sbjct: 1093 KVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEI 1152
Query: 150 ------RTTTL----DLINMEFI-------------------VEIDPERLEKSGLTMEKV 180
R+T + ++I + F +E+D + LTM +V
Sbjct: 1153 YYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQV 1212
Query: 181 LKKLQSSFKSAEF----EMEGYTLI-----VRPKKFEKISD------LRRLAEKVKKH-R 224
++++ +FK+ F E LI VRPK + ++ L+++ + ++
Sbjct: 1213 GERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENIT 1272
Query: 225 LKGLSGVGKTIVRK-------------EGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNNI 271
L+G+ + + ++ K + E+V+ T+G N +V+ VPG+DPTR TN+
Sbjct: 1273 LRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSF 1332
Query: 272 HEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGE 331
+I EVLGIEA R A+ +E+ N + G V+ RH+ L+ D+MT G + + RHG
Sbjct: 1333 IDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRS 1392
Query: 332 KASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
L R +FE TV+ LFEA E+D+ GV ENV++GQ P+GTG
Sbjct: 1393 NTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTG 1439
>emb|CAA26904.1| (X03128) put. RNA polymerase II largest subunit [Saccharomyces
cerevisiae]
Length = 1726
Score = 234 bits (590), Expect = 2e-60
Identities = 142/407 (34%), Positives = 225/407 (54%), Gaps = 63/407 (15%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++Y+LTK + ++ + ++ R++V PGE VG +AAQSIGEP+TQMTLNTFH+AGVA
Sbjct: 1033 QEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASK 1092
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLA----- 149
VT G+PR+ EI++ KN TP +TVYL+ H D+E+A+ + IE TTL+++
Sbjct: 1093 KVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEI 1152
Query: 150 ------RTTTL----DLINMEFI-------------------VEIDPERLEKSGLTMEKV 180
R+T + ++I + F +E+D + LTM +V
Sbjct: 1153 YYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQV 1212
Query: 181 LKKLQSSFKSAEF----EMEGYTLI-----VRPKKFEKISD------LRRLAEKVKKH-R 224
++++ +FK+ F E LI VRPK + ++ L+++ + ++
Sbjct: 1213 GERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENIT 1272
Query: 225 LKGLSGVGKTIVRK-------------EGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNNI 271
L+G+ + + ++ K + E+V+ T+G N +V+ VPG+DPTR TN+
Sbjct: 1273 LRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSF 1332
Query: 272 HEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGE 331
+I EVLGIEA R A+ +E+ N + G V+ RH+ L+ D+MT G + + RHG
Sbjct: 1333 IDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRS 1392
Query: 332 KASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
L R +FE TV+ LFEA E+D+ GV ENV++GQ P+GTG
Sbjct: 1393 NTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTG 1439
>gb|AAF48509.1| (AE003500) CG17209 gene product [Drosophila melanogaster]
Length = 1259
Score = 223 bits (563), Expect = 2e-57
Identities = 142/376 (37%), Positives = 210/376 (55%), Gaps = 19/376 (5%)
Query: 24 QELYEKLIKYNEKYK-LTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMT 82
Q+ YEK I + + LT ++ + + Y RA+ EPG AVG +AAQSIGEP TQMT
Sbjct: 858 QKRYEKCIDLCHQIECLTTEQLLQFVRRINDRYNRAVTEPGTAVGAIAAQSIGEPGTQMT 917
Query: 83 LNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEG 142
L TFH+AGVA +N+T G+PRI+EI++A K STP++T L+ H E A +V RIE
Sbjct: 918 LKTFHFAGVASMNITQGVPRIVEIINATKTISTPIITAELENCH--SMEFARQVKARIEK 975
Query: 143 TTLENLARTTTLDL--INMEFIVEIDPERLEKSGLTMEK---VLKKLQSSFKSAEFEMEG 197
TTL L+ + + + +D R++ GL ++ V L+S + ++E
Sbjct: 976 TTLAELSSYVEVVCGPYSCYLAIGVDMARIKLLGLHIDLDTIVFSILKSRMRVKPTQVEV 1035
Query: 198 YT----LIVRPKKFEKIS---DLRRLAEKVKKHRLKGLSGVGKTIVR----KEGDEYVIY 246
++VR + + +L RLA ++ + GL + + ++ ++ Y +
Sbjct: 1036 VASQSRIVVRVEATRTSTINAELARLALSLQNVVVAGLPNINRAVIAVDDARQPPTYKLC 1095
Query: 247 TEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRH 306
EG + V+ GV RT++NNI EI + LGIEAAR I+ EI M G+ VD RH
Sbjct: 1096 IEGYGLRDVIATYGVVGKRTRSNNICEIYQTLGIEAARTIIMSEITEVMEGHGMSVDWRH 1155
Query: 307 IMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIEN 366
IML+A MT G V I RHG+ + SV A+FE T HLF+AA G+ D ++GV E
Sbjct: 1156 IMLLASQMTARGEVLGITRHGLAKMRESVFNLASFEKTADHLFDAAYYGQTDAINGVSER 1215
Query: 367 VLIGQPVPVGTGMVKL 382
+++G P +GTG+ KL
Sbjct: 1216 IILGMPACIGTGIFKL 1231
>gi|5902062 polymerase (RNA) III (DNA directed) (155kD) [Homo sapiens]
>gi|3122765|sp|O14802|RPC1_HUMAN DNA-DIRECTED RNA
POLYMERASE III LARGEST SUBUNIT (RPC155)
>gi|2460208|gb|AAB86536.1| (AF021351) RNA polymerase III
largest subunit [Homo sapiens]
Length = 1391
Score = 222 bits (561), Expect = 4e-57
Identities = 141/373 (37%), Positives = 213/373 (56%), Gaps = 18/373 (4%)
Query: 38 KLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVT 97
++T +VE ++ +Y RA +EPG AVG + AQSIGEP TQMTL TFH+ GVA +N+T
Sbjct: 1005 RITPTQVEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFGGVASMNIT 1064
Query: 98 LGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLI 157
LG+PRI EI++A K STP++T LD++ D + A V RIE T L ++ +
Sbjct: 1065 LGVPRIKEIINASKAISTPIITAQLDKDD--DADYARLVKGRIEKTLLGEISEYIEEVFL 1122
Query: 158 --NMEFIVEIDPE-----RLEKSGLTMEKVLKKLQSSFKSAEFEMEGYTLI-VRPKKFEK 209
+ +V++ E RLE + T+ + + K + + G ++ V P++ K
Sbjct: 1123 PDDCFILVKLSLERIRLLRLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSK 1182
Query: 210 IS---DLRRLAEKVKKHRLKGLSGVGKTIV----RKEGDEYVIYTEGSNFKQVLKVPGVD 262
S L+ L E + K ++G+ V + ++ + ++Y + EG N + V+ GV
Sbjct: 1183 SSMYYVLQFLKEDLPKVVVQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVK 1242
Query: 263 PTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTM-REQGLEVDIRHIMLVADIMTLDGVVR 321
TRT +NN +E+ + LGIEAAR II EI TM G+ +D RH+ML++D+MT G V
Sbjct: 1243 GTRTTSNNTYEVEKTLGIEAARTTIINEIQYTMVVNHGMSIDRRHVMLLSDLMTYKGEVL 1302
Query: 322 PIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVK 381
I R G+ K SVL A+FE T HLF+AA G+ D++ GV E +++G P+ +GTG+ K
Sbjct: 1303 GITRFGLAKMKESVLMLASFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFK 1362
Query: 382 LTMKLPLRPQKEK 394
L K P K
Sbjct: 1363 LLHKADRDPNPPK 1375
>gi|11431655 polymerase (RNA) III (DNA directed) (155kD) [Homo sapiens]
Length = 539
Score = 222 bits (559), Expect = 7e-57
Identities = 139/372 (37%), Positives = 210/372 (56%), Gaps = 17/372 (4%)
Query: 38 KLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVT 97
++T +VE ++ +Y RA +EPG AVG + AQSIGEP TQMTL TFH+AGVA +N+T
Sbjct: 154 RITPTQVEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNIT 213
Query: 98 LGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLI 157
LG+PRI EI++A K STP++T LD++ D + A V RIE T L ++ +
Sbjct: 214 LGVPRIKEIINASKAISTPIITAQLDKDD--DADYARLVKGRIEKTLLGEISEYIEEVFL 271
Query: 158 NME--FIVEIDPER-----LEKSGLTMEKVLKKLQSSFKSAEFEMEGYTLI-VRPKKFEK 209
+ +V++ ER LE + T+ + + K + + G ++ V P++ K
Sbjct: 272 PDDCFILVKLSLERIRLLRLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSK 331
Query: 210 ISD---LRRLAEKVKKHRLKGLSGVGKTIVRKEG----DEYVIYTEGSNFKQVLKVPGVD 262
S L+ L E + K ++G+ V + ++ + ++Y + EG N + V+ GV
Sbjct: 332 SSMYYVLQFLKEDLPKVVVQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVK 391
Query: 263 PTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRP 322
TRT +NN +E+ + LGIEAAR II EI TM G+ +D RH+ML++D+MT G
Sbjct: 392 GTRTTSNNTYEVEKTLGIEAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEGLG 451
Query: 323 IGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKL 382
I R G+ SVL FE T HLF+AA G+ D++ GV E +++G P+ +GTG+ KL
Sbjct: 452 ITRFGLSKMNESVLMLTCFEKTADHLFDAAYLGQKDSVCGVSECIIMGIPMNIGTGLFKL 511
Query: 383 TMKLPLRPQKEK 394
K P K
Sbjct: 512 LHKADRDPNPPK 523
>gb|AAC18417.1| (U90211) RNA polymerase II largest subunit [Acanthamoeba castellanii]
Length = 1569
Score = 220 bits (556), Expect = 2e-56
Identities = 136/414 (32%), Positives = 218/414 (51%), Gaps = 66/414 (15%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++Y+L + + ++ E+ + ++L +PGE +G +AAQSIGEP+TQMTLNTFH+AGV+
Sbjct: 963 QEYRLDQISWDWLLGEITDRFYKSLCDPGEMIGALAAQSIGEPATQMTLNTFHFAGVSAK 1022
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ E+++ K TP +TVYL+ D E A+ V ++ TTL ++ T +
Sbjct: 1023 NVTLGVPRLKELINIAKTIKTPSLTVYLEPHCSRDHEAAKNVQCSLQHTTLRDVTAATEI 1082
Query: 155 ---------------DLINMEFI-----------------VEIDPERLEKSGLTMEKVLK 182
D + F+ +E++ E++ + L+M+++ +
Sbjct: 1083 FYDPDPVNTVITEDQDFVRAYFLMPEEEINTSNLSPWLLRIELNREKMTDTKLSMQEIAE 1142
Query: 183 KLQSSF----KSAEFEMEGYTLIVR-----------PKKFEKISDLRRLAEKVKKHRL-- 225
++ + F + LI+R P + + D ++++ + L
Sbjct: 1143 RIHADFGGDLNCIYNDDNADKLILRIRINNDEENKAPDQEGSVGDDDVFLKQIESNMLTE 1202
Query: 226 ---KGLSGVGKTIVRKE--------------GDEYVIYTEGSNFKQVLKVPGVDPTRTKT 268
KG+ G+ K +R++ +E V+ TEG+N V+ P VD TRT +
Sbjct: 1203 MDLKGIEGIKKVFIREDKNKVAIDARGEYTKANELVLDTEGTNLLAVMSHPDVDHTRTTS 1262
Query: 269 NNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGV 328
NNI E EVLGIEA RNA++ E+ N + G V+ RH+ ++AD+MT G + I RHG+
Sbjct: 1263 NNIIETIEVLGIEAVRNALLRELRNVISFDGAYVNYRHLAILADVMTYRGHLMAITRHGI 1322
Query: 329 VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKL 382
+ L R +FE T L EAA E+D LSGV EN+L+GQ P+GTG L
Sbjct: 1323 NRVETGCLMRCSFEETADILLEAATFSELDPLSGVSENILLGQLPPLGTGCFDL 1376
>sp|P36594|RPB1_SCHPO DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (RNA POLYMERASE II
SUBUNIT 1) >gi|283079|pir||S26849 DNA-directed RNA
polymerase (EC 2.7.7.6) II largest chain - fission yeast
(Schizosaccharomyces pombe) >gi|5055|emb|CAA39916.1|
(X56564) RNA polymerase II large subunit
[Schizosaccharomyces pombe] >gi|6018696|emb|CAB57941.1|
(AL121795) DNA-directed RNA polymerase II largest subunit
[Schizosaccharomyces pombe]
Length = 1752
Score = 220 bits (556), Expect = 2e-56
Identities = 144/409 (35%), Positives = 214/409 (52%), Gaps = 66/409 (16%)
Query: 36 KYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEIN 95
+Y+L K E I+ EV +++A+V PGE VGT+AAQSIGEP+TQMTLNTFHYAGV+ N
Sbjct: 1037 EYRLNKVAFEWIMGEVEARFQQAVVSPGEMVGTLAAQSIGEPATQMTLNTFHYAGVSSKN 1096
Query: 96 VTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL- 154
VTLG+PR+ EI++ KN TP +T+YL + + A+ V +IE TTL + T +
Sbjct: 1097 VTLGVPRLKEILNVAKNIKTPSLTIYLMPWIAANMDLAKNVQTQIEHTTLSTVTSATEIH 1156
Query: 155 --------------DLINMEFIV-------------------EIDPERLEKSGLTMEKVL 181
D + F + E+D ++ L+M V
Sbjct: 1157 YDPDPQDTVIEEDKDFVEAFFAIPDEEVEENLYKQSPWLLRLELDRAKMLDKKLSMSDVA 1216
Query: 182 KKLQSSFKSAEF----EMEGYTLIVRPKKFE----KISDLRRLAEK------VKKHRLKG 227
K+ SF+ F E LI+R + K D + E+ ++ H L+
Sbjct: 1217 GKIAESFERDLFTIWSEDNADKLIIRCRIIRDDDRKAEDDDNMIEEDVFLKTIEGHMLES 1276
Query: 228 LSGVG-----------KTIVRK-------EGDEYVIYTEGSNFKQVLKVPGVDPTRTKTN 269
+S G IVR+ DE+V+ T+G N + + V GVD TRT +N
Sbjct: 1277 ISLRGVPNITRVYMMEHKIVRQIEDGTFERADEWVLETDGINLTEAMTVEGVDATRTYSN 1336
Query: 270 NIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVV 329
+ EI ++LGIEA R+A+++E+ N + G V+ RH+ L+ D+MT G + I RHG+
Sbjct: 1337 SFVEILQILGIEATRSALLKELRNVIEFDGSYVNYRHLALLCDVMTSRGHLMAITRHGIN 1396
Query: 330 GEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
+ L R +FE TV+ L +AA GE D+ G+ EN+++GQ P+GTG
Sbjct: 1397 RAETGALMRCSFEETVEILMDAAASGEKDDCKGISENIMLGQLAPMGTG 1445
>emb|CAA34086.1| (X15970) RNA polymerase beta' subunit (AA 215) [Methanococcus
vannielii]
Length = 216
Score = 218 bits (550), Expect = 8e-56
Identities = 106/188 (56%), Positives = 143/188 (75%)
Query: 206 KFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIYTEGSNFKQVLKVPGVDPTR 265
K + LR+ KV++ LKG+ + + I+RKE DEYV+Y+EGSN K+V ++ GVD T+
Sbjct: 28 KTPSLKALRKRLPKVREIHLKGVPNIKRVIIRKEIDEYVLYSEGSNLKEVFEIDGVDTTK 87
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T TNNI EI +VLG+EAARNAII E+ T+ QGL VD RH+M+VAD+MT DGVV+PIGR
Sbjct: 88 TTTNNIVEIQDVLGVEAARNAIIREMDATLGNQGLTVDKRHLMMVADLMTTDGVVKPIGR 147
Query: 326 HGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTMK 385
HG+ GEKASVLARAAFE TV+HL+ A+ RG VD+LSGV+EN+++G+P+ +GTG + + +K
Sbjct: 148 HGIGGEKASVLARAAFEETVKHLYSASMRGYVDDLSGVVENIIVGKPISMGTGCINVCIK 207
Query: 386 LPLRPQKE 393
KE
Sbjct: 208 KEYEEGKE 215
>dbj|BAA96933.1| (AB019231) DNA-directed RNA polymerase II largest chain [Arabidopsis
thaliana]
Length = 1383
Score = 216 bits (545), Expect = 3e-55
Identities = 137/384 (35%), Positives = 212/384 (54%), Gaps = 21/384 (5%)
Query: 21 SVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQ 80
S Q LY+ + E L ++ + V Y +E G A+GT+ AQSIGEP TQ
Sbjct: 986 SPPQVLYKASGQKYEILPLIYINMQVFVKICVFRYREKKIEAGTAIGTIGAQSIGEPGTQ 1045
Query: 81 MTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRI 140
MTL TFH+AGVA +N+T G+PRI EI++A KN STP+++ L E+ + A V RI
Sbjct: 1046 MTLKTFHFAGVASMNITQGVPRINEIINASKNISTPVISAEL--ENPLELTSARWVKGRI 1103
Query: 141 EGTTLENLARTTTLDLINMEFIVEI--DPERLEKSGLTM------EKVLKKLQSSFKSAE 192
E TTL +A + + + + V I D + +E++ L++ +LK + +
Sbjct: 1104 EKTTLGQVAESIEVLMTSTSASVRIILDNKIIEEACLSITPWSVKNSILKTPRIKLNDND 1163
Query: 193 FEMEGYTLIVRP--KKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDE-------- 242
+ L + P K +L L + + G+ V + +V ++ D+
Sbjct: 1164 IRVLDTGLDITPVVDKSRAHFNLHNLKNVLPNIIVNGIKTVERVVVAEDMDKSKQIDGKT 1223
Query: 243 -YVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLE 301
+ ++ EG+N V+ PG++ T +NN+ E+++ LGIEAAR II+EI M G+
Sbjct: 1224 KWKLFVEGTNLLAVMGTPGINGRTTTSNNVVEVSKTLGIEAARTTIIDEIGTVMGNHGMS 1283
Query: 302 VDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLS 361
+DIRH+ML+AD+MT G V I R G+ SVL +A+FE T HLF AA G+VDN+
Sbjct: 1284 IDIRHMMLLADVMTYRGEVLGIQRTGIQKMDKSVLMQASFERTGDHLFSAAASGKVDNIE 1343
Query: 362 GVIENVLIGQPVPVGTGMVKLTMK 385
GV E V++G P+ +GTG++K+ +
Sbjct: 1344 GVTECVIMGIPMKLGTGILKVLQR 1367
>sp|O94666|RPC1_SCHPO DNA-DIRECTED RNA POLYMERASE III LARGEST SUBUNIT
>gi|7492545|pir||T40607 probable dna-directed rna
polymerase iii largest subunit - fission yeast
(Schizosaccharomyces pombe) >gi|4467280|emb|CAB37604.1|
(AL035570) putative dna-directed rna polymerase iii
largest subunit [Schizosaccharomyces pombe]
Length = 1405
Score = 215 bits (543), Expect = 5e-55
Identities = 145/426 (34%), Positives = 229/426 (53%), Gaps = 58/426 (13%)
Query: 1 MVSSSTIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALV 60
M+ + L + +G + K++ E +I+ EK ++ + +D ++Y RA V
Sbjct: 988 MLEEPDMDDLDDMEGDEFAPVAKRKSVENIIRVTEK------QLRSFVDRCWEKYMRAKV 1041
Query: 61 EPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTV 120
EPG AVG + AQSIGEP TQMTL TFH+AGVA TLG+PRI EI++A K STP++T
Sbjct: 1042 EPGTAVGAIGAQSIGEPGTQMTLKTFHFAGVAA-QTTLGVPRIKEIINAAKTISTPIITG 1100
Query: 121 YLDEEHRYDREKAEEVARRIEGTTLENLAR---------TTTLDL-INMEFIVEIDPE-- 168
L + D A V RIE T L+++ TT L + +N + I ++ +
Sbjct: 1101 QLINDR--DERSARVVKGRIEKTYLKDVTSYIEEVYGPVTTYLSIQVNFDTISKLQLDIT 1158
Query: 169 --------------RLEKSGLTMEKVLKKLQ----SSFKSAEFEMEGYTLIVRPKKFEKI 210
++ +T+ L+++ S KS+E E+ + ++
Sbjct: 1159 LADIAAAIWNTPKLKIPSQQVTVNNTLQQIHVHTSSDGKSSETEV-----------YYRL 1207
Query: 211 SDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNN 270
+R+ V + G+ + ++++ +E + ++ EG+ + V+ G+ T+T TN+
Sbjct: 1208 QTYKRVLPDVV---VAGIPTINRSVINQESGKIELFMEGTGLQAVMNTEGIVGTKTSTNH 1264
Query: 271 IHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVG 330
+ E+ +VLGIEAAR +II EI TM + GL VD RHIML+ D+MT G V I R GV
Sbjct: 1265 VMEMKDVLGIEAARYSIISEIGYTMAKHGLTVDPRHIMLLGDVMTCKGEVLGITRFGVAK 1324
Query: 331 EKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTMKLPLRP 390
K SVLA A+FE T HLF AA R D++ G+ E +++G+ P+GT + +L +R
Sbjct: 1325 MKDSVLALASFEKTTDHLFNAAARFAKDSIEGISECIVLGKLAPIGTNVFQL-----IRR 1379
Query: 391 QKEKEE 396
+E+EE
Sbjct: 1380 TEEEEE 1385
>dbj|BAB12227.1| (AB017184) RNA polymerase II largest subunit [Aspergillus oryzae]
Length = 1748
Score = 214 bits (540), Expect = 1e-54
Identities = 136/413 (32%), Positives = 215/413 (51%), Gaps = 71/413 (17%)
Query: 36 KYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEIN 95
+Y + K + +I + + +A GE VG +AAQSIGEP+TQMTLNTFH+AGV+ N
Sbjct: 1054 EYSMNKLAFQHVIGAIESRFAKANAPAGEMVGVLAAQSIGEPATQMTLNTFHFAGVSSKN 1113
Query: 96 VTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL- 154
VTLG+PR+ EI++ N TP MTVY + +D+E A+++ +E T+L ++ T +
Sbjct: 1114 VTLGVPRLKEILNVATNIKTPSMTVYQEPGRTHDKEGAKQLRSVVEHTSLRSVTEATEIY 1173
Query: 155 --------------DLINMEFIVEID-------------------PERLEKSGLTMEKVL 181
D++ FI+ D P+ L+K GLT++ V
Sbjct: 1174 YDPDIQSTVIENDRDMVESYFIIPEDVTDDSSRQSKWLLRIILSRPKLLDK-GLTVQDVA 1232
Query: 182 KKLQSSF----------KSAEFEMEGYTLIVRPKKFEKISDLRR--LAEKVKKH-----R 224
+++ ++ +A+ ++ I K+ E D+ +K+++H
Sbjct: 1233 TRIKQAYPKDIAVIFSDNNADEQVIRIRQIQDHKEDEDDDDIEYDVTLKKLEQHLLDTLT 1292
Query: 225 LKGLSGVGKTIVRKEGD-------------------EYVIYTEGSNFKQVLKVPGVDPTR 265
L+G++GV + + ++ E+V+ T GS +VL VPGVD TR
Sbjct: 1293 LRGVNGVERAFINEKSKVRVLEDGSLFTSKVDPLCKEWVLETSGSALGEVLAVPGVDATR 1352
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N E+ EV GIEAAR A++ E+ + G V+ RH+ L+ D+MT+ G + P+ R
Sbjct: 1353 TYSNQFIEVFEVFGIEAARTAVLRELTQVLAFDGSYVNHRHLALLVDVMTVRGYLTPVTR 1412
Query: 326 HGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
HG+ L R +FE TV+ L EAA GE+D+ GV EN+++GQ P GTG
Sbjct: 1413 HGINRADNGALMRCSFEETVEILLEAAAFGELDDCRGVSENLILGQMAPAGTG 1465
>pir||T34157 hypothetical protein C42D4.8 - Caenorhabditis elegans
>gi|1118158|gb|AAA83341.1| (U41991) coded for by C.
elegans cDNA yk1b8.5; coded for by C. elegans cDNA
yk34b10.5; coded for by C. elegans cDNA yk12b5.5; coded
for by C. elegans cDNA yk2e2.5; coded for by C. elegans
cDNA CEESM18R; coded for by C. elegans cDNA yk14f4.3;
coded for >
Length = 1388
Score = 212 bits (535), Expect = 4e-54
Identities = 145/383 (37%), Positives = 214/383 (55%), Gaps = 42/383 (10%)
Query: 29 KLIKYNEKYK--------LTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQ 80
K+ K E YK LTK ++ + I+ + RA+ EPGE PSTQ
Sbjct: 1001 KICKNLEAYKTSLLANSCLTKTQLCSFIELCYYKVARAITEPGE------------PSTQ 1048
Query: 81 MTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRI 140
MTL TFH+AGVA +N+T G+PRI EI++A K STP++T L + YD A V RI
Sbjct: 1049 MTLKTFHFAGVASMNITQGVPRIKEIINAVKTISTPIITAALLDP--YDESLARRVKARI 1106
Query: 141 EGTTLENLARTTTLDLINMEF--IVEIDPERLEKSGLT--MEKVLKKLQSS-----FKSA 191
E TTL + + ++ +V+++ +R+ L ME + + +S +
Sbjct: 1107 EKTTLGEICDYIEEVYLPDDYFLLVKLNSKRIRLLQLEVCMESISYAIATSKVCPQMRGC 1166
Query: 192 EFEMEGYTLI-VRPKKFEKISDLRRLAEKVKKHRL-----KGLSGVGKTIVR---KEGDE 242
+ G T++ +RP K+S + + ++ K+ L KG+ V + ++ K+GD
Sbjct: 1167 KIVAHGKTMMAIRPPSTSKLS--KTMTMQILKYSLANVVVKGIPSVNRCVIHADEKKGDF 1224
Query: 243 YVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEV 302
Y + EG++F+ VL GVDP +T NN +A+VLGIEAAR+ II EI+ TM G+ +
Sbjct: 1225 YSLLVEGTDFRSVLSSVGVDPRKTNFNNALVVADVLGIEAARSCIINEIIATMDAHGIGL 1284
Query: 303 DIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSG 362
D RH+ML+AD+MT G V I R+G+V K SVL A+FE T+ HLFEAA + D + G
Sbjct: 1285 DRRHVMLLADVMTYRGEVLGITRNGLVKMKDSVLLLASFEKTMDHLFEAAFFSQRDVIHG 1344
Query: 363 VIENVLIGQPVPVGTGMVKLTMK 385
V E +++G P+ VGTG KL K
Sbjct: 1345 VSECIIMGTPMTVGTGTFKLMQK 1367
>emb|CAB42796.1| (Y18877) largest subunit of the RNA polymerase II complex [Drosophila
madeirensis]
Length = 1889
Score = 210 bits (529), Expect = 2e-53
Identities = 139/421 (33%), Positives = 219/421 (52%), Gaps = 70/421 (16%)
Query: 34 NEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAE 93
+E+++L+ E +I E+ +++A PGE VG +AAQS+GEP+TQMTLNTFH+AGV+
Sbjct: 1047 SEEFRLSTEAFEWLIGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSS 1106
Query: 94 INVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT- 152
NVTLG+PR+ EI++ K P P +TV+L D EKA+ V R+E TTL + T
Sbjct: 1107 KNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTA 1166
Query: 153 ---------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKK 183
T+ + EF+ +E+D +R+ LTME++ +K
Sbjct: 1167 IYYDPDPQRTVISEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEK 1226
Query: 184 LQSSF---KSAEFEMEGYTLIV--------RPKKF-------EKISD---LRRL-AEKVK 221
+ F + F + +V KF +K+ D LR + A +
Sbjct: 1227 INVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLS 1286
Query: 222 KHRLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDP 263
L+G+ +GK ++ + G+ E+++ T+G++ +VL VDP
Sbjct: 1287 DMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDP 1346
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
RT +N+I EI +VLGIEA R ++ +E+ ++ GL V+ RH+ L+ D+MT G + I
Sbjct: 1347 VRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAI 1406
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
RHG+ + L R +FE TV L +AA E D + GV EN+++GQ +GTG L
Sbjct: 1407 TRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLL 1466
Query: 384 M 384
+
Sbjct: 1467 L 1467
>emb|CAB42800.1| (Y18876) largest subunit of the RNA polymerase II complex [Drosophila
subobscura] >gi|9587179|gb|AAF89193.1|AF272643_1
(AF272643) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587181|gb|AAF89194.1|AF272644_1
(AF272644) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587183|gb|AAF89195.1|AF272645_1
(AF272645) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587185|gb|AAF89196.1|AF272646_1
(AF272646) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587187|gb|AAF89197.1|AF272647_1
(AF272647) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587189|gb|AAF89198.1|AF272648_1
(AF272648) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587191|gb|AAF89199.1|AF272649_1
(AF272649) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587193|gb|AAF89200.1|AF272650_1
(AF272650) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587195|gb|AAF89201.1|AF272651_1
(AF272651) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587197|gb|AAF89202.1|AF272652_1
(AF272652) RNA polymerase II largest subunit [Drosophila
subobscura] >gi|9587199|gb|AAF89203.1|AF272653_1
(AF272653) RNA polymerase II largest subunit [Drosophila
subobscura]
Length = 1889
Score = 210 bits (529), Expect = 2e-53
Identities = 139/421 (33%), Positives = 219/421 (52%), Gaps = 70/421 (16%)
Query: 34 NEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAE 93
+E+++L+ E +I E+ +++A PGE VG +AAQS+GEP+TQMTLNTFH+AGV+
Sbjct: 1047 SEEFRLSTEAFEWLIGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSS 1106
Query: 94 INVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT- 152
NVTLG+PR+ EI++ K P P +TV+L D EKA+ V R+E TTL + T
Sbjct: 1107 KNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTA 1166
Query: 153 ---------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKK 183
T+ + EF+ +E+D +R+ LTME++ +K
Sbjct: 1167 IYYDPDPQRTVISEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEK 1226
Query: 184 LQSSF---KSAEFEMEGYTLIV--------RPKKF-------EKISD---LRRL-AEKVK 221
+ F + F + +V KF +K+ D LR + A +
Sbjct: 1227 INVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLS 1286
Query: 222 KHRLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDP 263
L+G+ +GK ++ + G+ E+++ T+G++ +VL VDP
Sbjct: 1287 DMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDP 1346
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
RT +N+I EI +VLGIEA R ++ +E+ ++ GL V+ RH+ L+ D+MT G + I
Sbjct: 1347 VRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAI 1406
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
RHG+ + L R +FE TV L +AA E D + GV EN+++GQ +GTG L
Sbjct: 1407 TRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLL 1466
Query: 384 M 384
+
Sbjct: 1467 L 1467
>emb|CAB42797.1| (Y18879) largest subunit of the RNA polymerase II complex [Drosophila
pseudoobscura]
Length = 1811
Score = 210 bits (528), Expect = 3e-53
Identities = 139/421 (33%), Positives = 219/421 (52%), Gaps = 70/421 (16%)
Query: 34 NEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAE 93
+E+++L+ E +I E+ +++A PGE VG +AAQS+GEP+TQMTLNTFH+AGV+
Sbjct: 969 SEEFRLSTEAFEWLIGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSS 1028
Query: 94 INVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT- 152
NVTLG+PR+ EI++ K P P +TV+L D EKA+ V R+E TTL + T
Sbjct: 1029 KNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTA 1088
Query: 153 ---------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKK 183
T+ + EF+ +E+D +R+ LTME++ +K
Sbjct: 1089 IYYDPDPQRTVISEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEK 1148
Query: 184 LQSSF---KSAEFEMEGYTLIV--------RPKKF-------EKISD---LRRL-AEKVK 221
+ F + F + +V KF +K+ D LR + A +
Sbjct: 1149 INVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLS 1208
Query: 222 KHRLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDP 263
L+G+ +GK ++ + G+ E+++ T+G++ +VL VDP
Sbjct: 1209 DMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDP 1268
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
RT +N+I EI +VLGIEA R ++ +E+ ++ GL V+ RH+ L+ D+MT G + I
Sbjct: 1269 IRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAI 1328
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
RHG+ + L R +FE TV L +AA E D + GV EN+++GQ +GTG L
Sbjct: 1329 TRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLL 1388
Query: 384 M 384
+
Sbjct: 1389 L 1389
>emb|CAB42795.1| (Y18878) largest subunit of the RNA polymerase II complex [Drosophila
guanche]
Length = 1889
Score = 210 bits (528), Expect = 3e-53
Identities = 139/421 (33%), Positives = 219/421 (52%), Gaps = 70/421 (16%)
Query: 34 NEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAE 93
+E+++L+ E +I E+ +++A PGE VG +AAQS+GEP+TQMTLNTFH+AGV+
Sbjct: 1047 SEEFRLSTEAFEWLIGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSS 1106
Query: 94 INVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT- 152
NVTLG+PR+ EI++ K P P +TV+L D EKA+ V R+E TTL + T
Sbjct: 1107 KNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTA 1166
Query: 153 ---------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKK 183
T+ + EF+ +E+D +R+ LTME++ +K
Sbjct: 1167 IYYDPDPQRTVISEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEK 1226
Query: 184 LQSSF---KSAEFEMEGYTLIV--------RPKKF-------EKISD---LRRL-AEKVK 221
+ F + F + +V KF +K+ D LR + A +
Sbjct: 1227 INVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLS 1286
Query: 222 KHRLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDP 263
L+G+ +GK ++ + G+ E+++ T+G++ +VL VDP
Sbjct: 1287 DMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDP 1346
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
RT +N+I EI +VLGIEA R ++ +E+ ++ GL V+ RH+ L+ D+MT G + I
Sbjct: 1347 IRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAI 1406
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
RHG+ + L R +FE TV L +AA E D + GV EN+++GQ +GTG L
Sbjct: 1407 TRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLL 1466
Query: 384 M 384
+
Sbjct: 1467 L 1467
>gb|AAF48057.1| (AE003486) RpII215 gene product [Drosophila melanogaster]
Length = 1887
Score = 209 bits (527), Expect = 4e-53
Identities = 138/421 (32%), Positives = 219/421 (51%), Gaps = 70/421 (16%)
Query: 34 NEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAE 93
+E+++L+ E ++ E+ +++A PGE VG +AAQS+GEP+TQMTLNTFH+AGV+
Sbjct: 1047 SEEFRLSTEAFEWLVGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSS 1106
Query: 94 INVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT- 152
NVTLG+PR+ EI++ K P P +TV+L D EKA+ V R+E TTL + T
Sbjct: 1107 KNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTA 1166
Query: 153 ---------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKK 183
T+ + EF+ +E+D +R+ LTME++ +K
Sbjct: 1167 IYYDPDPQRTVISEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEK 1226
Query: 184 LQSSF---KSAEFEMEGYTLIV--------RPKKF-------EKISD---LRRL-AEKVK 221
+ F + F + +V KF +K+ D LR + A +
Sbjct: 1227 INVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLS 1286
Query: 222 KHRLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDP 263
L+G+ +GK ++ + G+ E+++ T+G++ +VL VDP
Sbjct: 1287 DMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDP 1346
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
RT +N+I EI +VLGIEA R ++ +E+ ++ GL V+ RH+ L+ D+MT G + I
Sbjct: 1347 IRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAI 1406
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
RHG+ + L R +FE TV L +AA E D + GV EN+++GQ +GTG L
Sbjct: 1407 TRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLL 1466
Query: 384 M 384
+
Sbjct: 1467 L 1467
>sp|P04052|RPB1_DROME DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT >gi|279533|pir||RNFF2L
DNA-directed RNA polymerase (EC 2.7.7.6) II 215K chain
[validated] - fruit fly (Drosophila melanogaster)
>gi|158332|gb|AAA28868.1| (M27431) RNA polymerase II
[Drosophila melanogaster]
Length = 1896
Score = 209 bits (527), Expect = 4e-53
Identities = 138/421 (32%), Positives = 219/421 (51%), Gaps = 70/421 (16%)
Query: 34 NEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAE 93
+E+++L+ E ++ E+ +++A PGE VG +AAQS+GEP+TQMTLNTFH+AGV+
Sbjct: 1047 SEEFRLSTEAFEWLVGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSS 1106
Query: 94 INVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT- 152
NVTLG+PR+ EI++ K P P +TV+L D EKA+ V R+E TTL + T
Sbjct: 1107 KNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTA 1166
Query: 153 ---------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKK 183
T+ + EF+ +E+D +R+ LTME++ +K
Sbjct: 1167 IYYDPDPQRTVISEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEK 1226
Query: 184 LQSSF---KSAEFEMEGYTLIV--------RPKKF-------EKISD---LRRL-AEKVK 221
+ F + F + +V KF +K+ D LR + A +
Sbjct: 1227 INVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLS 1286
Query: 222 KHRLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDP 263
L+G+ +GK ++ + G+ E+++ T+G++ +VL VDP
Sbjct: 1287 DMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDP 1346
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
RT +N+I EI +VLGIEA R ++ +E+ ++ GL V+ RH+ L+ D+MT G + I
Sbjct: 1347 IRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAI 1406
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
RHG+ + L R +FE TV L +AA E D + GV EN+++GQ +GTG L
Sbjct: 1407 TRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLL 1466
Query: 384 M 384
+
Sbjct: 1467 L 1467
>gi|6677795 RNA polymerase II 1 [Mus musculus] >gi|90464|pir||A28490 DNA-directed
RNA polymerase (EC 2.7.7.6) II largest chain - mouse
>gi|200794|gb|AAA40071.1| (M12130) RNA polymerase II [Mus
musculus]
Length = 1932
Score = 208 bits (525), Expect = 7e-53
Identities = 133/420 (31%), Positives = 215/420 (50%), Gaps = 70/420 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+++L+ + ++ E+ ++ +A+ PGE VG +AAQS+GEP+TQMTLNTFHYAGV+
Sbjct: 1056 EEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAK 1115
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ E+++ K P TP +TV+L + D E+A+++ R+E TTL + T +
Sbjct: 1116 NVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAI 1175
Query: 155 ---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVLKKL 184
+ +N+ + VE+D + + LTME++ +K+
Sbjct: 1176 YYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKI 1235
Query: 185 QSSFKS------AEFEMEGYTLIVRPKKFE--KISDLRRLAEKVKKH------------- 223
+ F + E L +R + K+ + + +K+
Sbjct: 1236 NAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTD 1295
Query: 224 -RLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPT 264
L+G+ + K I+ ++G+ E+++ T+G + +VL VDP
Sbjct: 1296 MTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPV 1355
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT +N+I EI VLGIEA R A+ E+ + + G V+ RH+ L+ D MT G + I
Sbjct: 1356 RTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAIT 1415
Query: 325 RHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
RHGV + L + +FE TV L EAA GE D + GV EN+++GQ P GTG L +
Sbjct: 1416 RHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLL 1475
>gi|4505939 polymerase (RNA) II (DNA directed) polypeptide A (220kD) [Homo
sapiens] >gi|11428046|ref|XP_008659.1| polymerase (RNA)
II (DNA directed) polypeptide A (220kD) [Homo sapiens]
>gi|133326|sp|P24928|RPB1_HUMAN DNA-DIRECTED RNA
POLYMERASE II LARGEST SUBUNIT (RPB1)
>gi|105878|pir||S21054 DNA-directed RNA polymerase (EC
2.7.7.6) II largest chain - human
>gi|36124|emb|CAA45125.1| (X63564) RNA polymerase II
largest subunit [Homo sapiens]
>gi|2443336|dbj|BAA22377.1| (D87294) RNA polymerase II
largest subunit [Cricetulus griseus]
Length = 1970
Score = 208 bits (525), Expect = 7e-53
Identities = 133/420 (31%), Positives = 215/420 (50%), Gaps = 70/420 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+++L+ + ++ E+ ++ +A+ PGE VG +AAQS+GEP+TQMTLNTFHYAGV+
Sbjct: 1056 EEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAK 1115
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ E+++ K P TP +TV+L + D E+A+++ R+E TTL + T +
Sbjct: 1116 NVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAI 1175
Query: 155 ---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVLKKL 184
+ +N+ + VE+D + + LTME++ +K+
Sbjct: 1176 YYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKI 1235
Query: 185 QSSFKS------AEFEMEGYTLIVRPKKFE--KISDLRRLAEKVKKH------------- 223
+ F + E L +R + K+ + + +K+
Sbjct: 1236 NAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTD 1295
Query: 224 -RLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPT 264
L+G+ + K I+ ++G+ E+++ T+G + +VL VDP
Sbjct: 1296 MTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPV 1355
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT +N+I EI VLGIEA R A+ E+ + + G V+ RH+ L+ D MT G + I
Sbjct: 1356 RTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAIT 1415
Query: 325 RHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
RHGV + L + +FE TV L EAA GE D + GV EN+++GQ P GTG L +
Sbjct: 1416 RHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLL 1475
>sp|P08775|RPB1_MOUSE DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (RPB1)
Length = 1970
Score = 208 bits (525), Expect = 7e-53
Identities = 133/420 (31%), Positives = 215/420 (50%), Gaps = 70/420 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+++L+ + ++ E+ ++ +A+ PGE VG +AAQS+GEP+TQMTLNTFHYAGV+
Sbjct: 1056 EEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAK 1115
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ E+++ K P TP +TV+L + D E+A+++ R+E TTL + T +
Sbjct: 1116 NVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAI 1175
Query: 155 ---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVLKKL 184
+ +N+ + VE+D + + LTME++ +K+
Sbjct: 1176 YYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKI 1235
Query: 185 QSSFKS------AEFEMEGYTLIVRPKKFE--KISDLRRLAEKVKKH------------- 223
+ F + E L +R + K+ + + +K+
Sbjct: 1236 NAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTD 1295
Query: 224 -RLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPT 264
L+G+ + K I+ ++G+ E+++ T+G + +VL VDP
Sbjct: 1296 MTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPV 1355
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT +N+I EI VLGIEA R A+ E+ + + G V+ RH+ L+ D MT G + I
Sbjct: 1356 RTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAIT 1415
Query: 325 RHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
RHGV + L + +FE TV L EAA GE D + GV EN+++GQ P GTG L +
Sbjct: 1416 RHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLL 1475
>gb|AAB58418.1| (U37500) RNA polymerase II largest subunit [Mus musculus]
Length = 1966
Score = 208 bits (525), Expect = 7e-53
Identities = 133/420 (31%), Positives = 215/420 (50%), Gaps = 70/420 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+++L+ + ++ E+ ++ +A+ PGE VG +AAQS+GEP+TQMTLNTFHYAGV+
Sbjct: 1056 EEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAK 1115
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ E+++ K P TP +TV+L + D E+A+++ R+E TTL + T +
Sbjct: 1116 NVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAI 1175
Query: 155 ---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVLKKL 184
+ +N+ + VE+D + + LTME++ +K+
Sbjct: 1176 YYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKI 1235
Query: 185 QSSFKS------AEFEMEGYTLIVRPKKFE--KISDLRRLAEKVKKH------------- 223
+ F + E L +R + K+ + + +K+
Sbjct: 1236 NAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTD 1295
Query: 224 -RLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPT 264
L+G+ + K I+ ++G+ E+++ T+G + +VL VDP
Sbjct: 1296 MTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPV 1355
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT +N+I EI VLGIEA R A+ E+ + + G V+ RH+ L+ D MT G + I
Sbjct: 1356 RTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAIT 1415
Query: 325 RHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
RHGV + L + +FE TV L EAA GE D + GV EN+++GQ P GTG L +
Sbjct: 1416 RHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLL 1475
>dbj|BAA22376.1| (D87293) RNA polymerase II largest subunit [Cricetulus griseus]
Length = 1970
Score = 208 bits (525), Expect = 7e-53
Identities = 133/420 (31%), Positives = 215/420 (50%), Gaps = 70/420 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+++L+ + ++ E+ ++ +A+ PGE VG +AAQS+GEP+TQMTLNTFHYAGV+
Sbjct: 1056 EEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAK 1115
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ E+++ K P TP +TV+L + D E+A+++ R+E TTL + T +
Sbjct: 1116 NVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAI 1175
Query: 155 ---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVLKKL 184
+ +N+ + VE+D + + LTME++ +K+
Sbjct: 1176 YYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKI 1235
Query: 185 QSSFKS------AEFEMEGYTLIVRPKKFE--KISDLRRLAEKVKKH------------- 223
+ F + E L +R + K+ + + +K+
Sbjct: 1236 NAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTD 1295
Query: 224 -RLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPT 264
L+G+ + K I+ ++G+ E+++ T+G + +VL VDP
Sbjct: 1296 MTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPV 1355
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT +N+I EI VLGIEA R A+ E+ + + G V+ RH+ L+ D MT G + I
Sbjct: 1356 RTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAIT 1415
Query: 325 RHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
RHGV + L + +FE TV L EAA GE D + GV EN+++GQ P GTG L +
Sbjct: 1416 RHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLL 1475
>sp|P35084|RPB1_DICDI DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
>gi|2117913|pir||A56823 DNA-directed RNA polymerase (EC
2.7.7.6) II largest chain - slime mold (Dictyostelium
discoideum) (fragment) >gi|263754|gb|AAB24966.1|
(S52651) RNA polymerase II largest subunit {C-terminal}
[Dictyostelium discoideum, Peptide Partial, 902 aa]
Length = 902
Score = 207 bits (521), Expect = 2e-52
Identities = 136/405 (33%), Positives = 214/405 (52%), Gaps = 62/405 (15%)
Query: 36 KYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEIN 95
+++LT+ + E+ ++ +AL PGE VG +AAQSIGEP+TQMTLNTFHYAGV+ N
Sbjct: 228 EFRLTEKAFLWVCGEIESKFLQALAHPGEMVGALAAQSIGEPATQMTLNTFHYAGVSSKN 287
Query: 96 VTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT--- 152
VTLG+PR+ +I++ K TP +T+YL D ++A+ V ++E TTL N+ T
Sbjct: 288 VTLGVPRLNQIINIAKQVKTPSLTIYLKPHMARDMDRAKIVKSQLEYTTLANVTSATEIY 347
Query: 153 -------TLDLINMEFI----------------------VEIDPERLEKSGLTM----EK 179
T+ + EF+ +E+D + LTM +
Sbjct: 348 YDPDPQNTIISEDAEFVNSYFELPDEEIDVHSMSPWLLRIELDRGMVTDKKLTMADITQC 407
Query: 180 VLKKLQSSFKSAEFEMEGYTLIVRPKKFE----KISD-------LRRLAEKVKKHR-LKG 227
V++ S + LI+R + E K +D LRR+ + L+G
Sbjct: 408 VVRDFGLSLNCIFSDDNAEKLILRIRMVESQETKGTDNDDDDQFLRRIESNMLSEMVLRG 467
Query: 228 LSGVGKTIVRKEG--------------DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHE 273
+ G+ K +R + +E+++ T+G + +V+ P VD TRT +N+I E
Sbjct: 468 IKGIKKVFMRTDEKIPKVTENSGFGVREEWILDTDGVSLLEVMSHPDVDHTRTTSNDIVE 527
Query: 274 IAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKA 333
I +VLGIEA RNA+++E+ + G V+ RH+ ++AD+MT G + I RHG+ +
Sbjct: 528 IIQVLGIEAVRNALLKELRAVISFDGSYVNYRHLAILADVMTYRGHLMAITRHGINRVET 587
Query: 334 SVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
L R +FE TV+ L +AA E D++ GV EN+++GQ P+GTG
Sbjct: 588 GPLMRCSFEETVEILMDAAMFSETDDVKGVTENIILGQLPPLGTG 632
>sp|P18616|RPB1_ARATH DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (VERSION 1)
>gi|16505|emb|CAA37130.1| (X52954) RNA polymerase II
[Arabidopsis thaliana]
Length = 1841
Score = 206 bits (520), Expect = 3e-52
Identities = 139/412 (33%), Positives = 213/412 (50%), Gaps = 64/412 (15%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+YKL++ E +I E+ + ++LV PGE +G VAAQSIGEP+TQMTLNTFHYAGV+
Sbjct: 1048 EEYKLSRERFEWVIGEIESRFLQSLVAPGEMIGCVAAQSIGEPATQMTLNTFHYAGVSAK 1107
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT-- 152
NVTLG+PR+ EI++ K TP ++VYL E +E A+ V +E TTL ++ + T
Sbjct: 1108 NVTLGVPRLREIINVAKRIKTPSLSVYLTPEASKSKEGAKTVQCALEYTTLRSVTQATEV 1167
Query: 153 --------TLDLINMEFI----------------------VEIDPERLEKSGLTMEKVLK 182
T+ + EF+ +E++ E + L+M + +
Sbjct: 1168 WYDPDPMSTIIEEDFEFVRSYYEMPDEDVSPDKISPWLLRIELNREMMVDKKLSMADIAE 1227
Query: 183 KLQSSFKS----AEFEMEGYTLIVR--------PK---KFEKISD---LRRL-AEKVKKH 223
K+ F + LI+R PK + E D L+++ + + +
Sbjct: 1228 KINLEFDDDLTCIFNDDNAQKLILRIRIMNDEGPKGELQDESAEDDVFLKKIESNMLTEM 1287
Query: 224 RLKGLSGVGKTIVR-------------KEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNN 270
L+G+ + K ++ K +E+++ TEG N V+ VDP RT +N+
Sbjct: 1288 ALRGIPDINKVFIKQVRKSRFDEEGGFKTSEEWMLDTEGVNLLAVMCHEDVDPKRTTSNH 1347
Query: 271 IHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVG 330
+ EI EVLGIEA R A+++E+ + G V+ RH+ ++ D MT G + I RHG+
Sbjct: 1348 LIEIIEVLGIEAVRRALLDELRVVISFDGSYVNYRHLAILCDTMTYRGHLMAITRHGINR 1407
Query: 331 EKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKL 382
L R +FE TV L +AA E D L GV EN+++GQ P+GTG +L
Sbjct: 1408 NDTGPLMRCSFEETVDILLDAAAYAETDCLRGVTENIMLGQLAPIGTGDCEL 1459
>emb|CAA21466.2| (AL031986) DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain
[Arabidopsis thaliana] >gi|7270532|emb|CAB81489.1|
(AL161588) DNA-directed RNA polymerase (EC 2.7.7.6) II
largest chain [Arabidopsis thaliana]
Length = 1840
Score = 206 bits (519), Expect = 3e-52
Identities = 139/412 (33%), Positives = 213/412 (50%), Gaps = 64/412 (15%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+YKL++ E +I E+ + ++LV PGE +G VAAQSIGEP+TQMTLNTFHYAGV+
Sbjct: 1054 EEYKLSREAFEWVIGEIESRFLQSLVAPGEMIGCVAAQSIGEPATQMTLNTFHYAGVSAK 1113
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT-- 152
NVTLG+PR+ EI++ K TP ++VYL E +E A+ V +E TTL ++ + T
Sbjct: 1114 NVTLGVPRLREIINVAKRIKTPSLSVYLTPEASKSKEGAKTVQCALEYTTLRSVTQATEV 1173
Query: 153 --------TLDLINMEFI----------------------VEIDPERLEKSGLTMEKVLK 182
T+ + EF+ +E++ E + L+M + +
Sbjct: 1174 WYDPDPMSTIIEEDFEFVRSYYEMPDEDVSPDKISPWLLRIELNREMMVDKKLSMADIAE 1233
Query: 183 KLQSSFKS----AEFEMEGYTLIVR--------PK---KFEKISD---LRRL-AEKVKKH 223
K+ F + LI+R PK + E D L+++ + + +
Sbjct: 1234 KINLEFDDDLTCIFNDDNAQKLILRIRIMNDEGPKGELQDESAEDDVFLKKIESNMLTEM 1293
Query: 224 RLKGLSGVGKTIVR-------------KEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNN 270
L+G+ + K ++ K +E+++ TEG N V+ VDP RT +N+
Sbjct: 1294 ALRGIPDINKVFIKQVRKSRFDEEGGFKTSEEWMLDTEGVNLLAVMCHEDVDPKRTTSNH 1353
Query: 271 IHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVG 330
+ EI EVLGIEA R A+++E+ + G V+ RH+ ++ D MT G + I RHG+
Sbjct: 1354 LIEIIEVLGIEAVRRALLDELRVVISFDGSYVNYRHLAILCDTMTYRGHLMAITRHGINR 1413
Query: 331 EKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKL 382
L R +FE TV L +AA E D L GV EN+++GQ P+GTG +L
Sbjct: 1414 NDTGPLMRCSFEETVDILLDAAAYAETDCLRGVTENIMLGQLAPIGTGDCEL 1465
>pir||JDMU1 DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain -
Arabidopsis thaliana
Length = 1834
Score = 206 bits (519), Expect = 3e-52
Identities = 139/412 (33%), Positives = 213/412 (50%), Gaps = 64/412 (15%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+YKL++ E +I E+ + ++LV PGE +G VAAQSIGEP+TQMTLNTFHYAGV+
Sbjct: 1048 EEYKLSREAFEWVIGEIESRFLQSLVAPGEMIGCVAAQSIGEPATQMTLNTFHYAGVSAK 1107
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT-- 152
NVTLG+PR+ EI++ K TP ++VYL E +E A+ V +E TTL ++ + T
Sbjct: 1108 NVTLGVPRLREIINVAKRIKTPSLSVYLTPEASKSKEGAKTVQCALEYTTLRSVTQATEV 1167
Query: 153 --------TLDLINMEFI----------------------VEIDPERLEKSGLTMEKVLK 182
T+ + EF+ +E++ E + L+M + +
Sbjct: 1168 WYDPDPMSTIIEEDFEFVRSYYEMPDEDVSPDKISPWLLRIELNREMMVDKKLSMADIAE 1227
Query: 183 KLQSSFKS----AEFEMEGYTLIVR--------PK---KFEKISD---LRRL-AEKVKKH 223
K+ F + LI+R PK + E D L+++ + + +
Sbjct: 1228 KINLEFDDDLTCIFNDDNAQKLILRIRIMNDEGPKGELQDESAEDDVFLKKIESNMLTEM 1287
Query: 224 RLKGLSGVGKTIVR-------------KEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNN 270
L+G+ + K ++ K +E+++ TEG N V+ VDP RT +N+
Sbjct: 1288 ALRGIPDINKVFIKQVRKSRFDEEGGFKTSEEWMLDTEGVNLLAVMCHEDVDPKRTTSNH 1347
Query: 271 IHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVG 330
+ EI EVLGIEA R A+++E+ + G V+ RH+ ++ D MT G + I RHG+
Sbjct: 1348 LIEIIEVLGIEAVRRALLDELRVVISFDGSYVNYRHLAILCDTMTYRGHLMAITRHGINR 1407
Query: 331 EKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKL 382
L R +FE TV L +AA E D L GV EN+++GQ P+GTG +L
Sbjct: 1408 NDTGPLMRCSFEETVDILLDAAAYAETDCLRGVTENIMLGQLAPIGTGDCEL 1459
>pir||I38186 RNA polymerase II largest subunit - human >gi|825713|emb|CAA52862.1|
(X74874) RNA polymerase II largest subunit [Homo sapiens]
Length = 1970
Score = 205 bits (517), Expect = 6e-52
Identities = 132/420 (31%), Positives = 214/420 (50%), Gaps = 70/420 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+++L+ + ++ E+ ++ +A+ PGE VG +AAQS+GEP+TQMTLNTFHYAGV+
Sbjct: 1056 EEFRLSGEAFDLLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAK 1115
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ E+++ K P TP +TV+L + D E+A+++ R+E TTL + T +
Sbjct: 1116 NVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAI 1175
Query: 155 ---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVLKKL 184
+ +N+ + VE+D + + LTME++ +K+
Sbjct: 1176 YYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKI 1235
Query: 185 QSSFKS------AEFEMEGYTLIVRPKKFE--KISDLRRLAEKVKKH------------- 223
+ F + E L +R + K+ + + +K+
Sbjct: 1236 NAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTD 1295
Query: 224 -RLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPT 264
L+G+ + K I+ ++G+ E+++ T+G + +VL VDP
Sbjct: 1296 MTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPV 1355
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT +N+I EI VLGIEA R A+ E+ + + G V+ RH+ L+ D MT G + I
Sbjct: 1356 RTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAIT 1415
Query: 325 RHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
RHGV + L + +FE TV L EAA GE + GV EN+++GQ P GTG L +
Sbjct: 1416 RHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESYPMKGVSENIMLGQLAPAGTGCFDLLL 1475
>sp|P31635|RPB0_ARATH DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (VERSION 2)
>gi|279535|pir||JDMU2 DNA-directed RNA polymerase (EC
2.7.7.6) II largest chain (version 2) - Arabidopsis
thaliana >gi|16494|emb|CAA36735.1| (X52494) DNA-directed
RNA polymerase [Arabidopsis thaliana]
Length = 1860
Score = 204 bits (514), Expect = 1e-51
Identities = 138/412 (33%), Positives = 212/412 (50%), Gaps = 64/412 (15%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+YKL++ E +I E+ + ++LV PGE +G V AQSIGEP+TQMTLNTFHYAGV+
Sbjct: 1074 EEYKLSREAFEWVIGEIESRFLQSLVAPGEMIGCVPAQSIGEPATQMTLNTFHYAGVSAK 1133
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT-- 152
NVTLG+PR+ EI++ K TP ++VYL E +E A+ V +E TTL ++ + T
Sbjct: 1134 NVTLGVPRLREIINVAKRIKTPSLSVYLTPEASKSKEGAKTVQCALEYTTLRSVTQATEV 1193
Query: 153 --------TLDLINMEFI----------------------VEIDPERLEKSGLTMEKVLK 182
T+ + EF+ +E++ E + L+M + +
Sbjct: 1194 WYDPDPMSTIIEEDFEFVRSYYEMPDEDVSPDKISPWLLRIELNREMMVDKKLSMADIAE 1253
Query: 183 KLQSSFKS----AEFEMEGYTLIVR--------PK---KFEKISD---LRRL-AEKVKKH 223
K+ F + LI+R PK + E D L+++ + + +
Sbjct: 1254 KINLEFDDDLTCIFNDDNAQKLILRIRIMNDEGPKGELQDESAEDDVFLKKIESNMLTEM 1313
Query: 224 RLKGLSGVGKTIVR-------------KEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNN 270
L+G+ + K ++ K +E+++ TEG N V+ VDP RT +N+
Sbjct: 1314 ALRGIPDINKVFIKQVRKSRFDEEGGFKTSEEWMLDTEGVNLLAVMCHEDVDPKRTTSNH 1373
Query: 271 IHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVG 330
+ EI EVLGIEA R A+++E+ + G V+ RH+ ++ D MT G + I RHG+
Sbjct: 1374 LIEIIEVLGIEAVRRALLDELRVVISFDGSYVNYRHLAILCDTMTYRGHLMAITRHGINR 1433
Query: 331 EKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKL 382
L R +FE TV L +AA E D L GV EN+++GQ P+GTG +L
Sbjct: 1434 NDTGPLMRCSFEETVDILLDAAAYAETDCLRGVTENIMLGQLAPIGTGDCEL 1485
>gi|6324690 RNA polymerase III large subunit; Rpo31p [Saccharomyces cerevisiae]
>gi|133356|sp|P04051|RPC1_YEAST DNA-DIRECTED RNA
POLYMERASE III LARGEST SUBUNIT (C160)
>gi|66978|pir||RNBY3L DNA-directed RNA polymerase (EC
2.7.7.6) III 160K chain - yeast (Saccharomyces
cerevisiae) >gi|4400|emb|CAA26905.1| (X03129) RNA
polymerase III largest subunit [Saccharomyces cerevisiae]
>gi|1050828|emb|CAA62123.1| (X90518) ORF O3254
[Saccharomyces cerevisiae] >gi|1164961|emb|CAA64036.1|
(X94335) YOR3254c [Saccharomyces cerevisiae]
>gi|1420309|emb|CAA99314.1| (Z75024) ORF YOR116c
[Saccharomyces cerevisiae]
Length = 1460
Score = 203 bits (510), Expect = 4e-51
Identities = 139/398 (34%), Positives = 213/398 (52%), Gaps = 32/398 (8%)
Query: 12 EKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAA 71
E +G D E+V + + ++ Y++++ V ++ + +Y +A +EPG A+G + A
Sbjct: 1038 ELQGIDPDETVPDNVKTSV---SQLYRISEKSVRKFLEIALFKYRKARLEPGTAIGAIGA 1094
Query: 72 QSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDRE 131
QSIGEP TQMTL TFH+AGVA +NVTLG+PRI EI++A K STP++ L ++ D
Sbjct: 1095 QSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASKVISTPIINAVLVNDN--DER 1152
Query: 132 KAEEVARRIEGTTLENLA-RTTTLDLINMEFI-VEIDPERLEKSGL--TMEKVLKKLQSS 187
A V R+E T L ++A + N+ FI V ID ++K L T+E + + +
Sbjct: 1153 AARVVKGRVEKTLLSDVAFYVQDVYKDNLSFIQVRIDLGTIDKLQLELTIEDIAVAITRA 1212
Query: 188 FK----------------SAEFEMEGY------TLIVRPKKFEKISDLRRLAEKVKKHRL 225
K + EGY T P + + +++L + +
Sbjct: 1213 SKLKIQASDVNIIGKDRIAINVFPEGYKAKSISTSAKEPSENDVFYRMQQLRRALPDVVV 1272
Query: 226 KGLSGVGKTIVRKEGD-EYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAAR 284
KGL + + ++ D + + EG + V+ GV +RT TN++ E+ VLGIEAAR
Sbjct: 1273 KGLPDISRAVINIRDDGKRELLVEGYGLRDVMCTDGVIGSRTTTNHVLEVFSVLGIEAAR 1332
Query: 285 NAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEIT 344
+II EI TM G+ VD RHI L+ D+MT G V I R G+ + SVL A+FE T
Sbjct: 1333 YSIIREINYTMSNHGMSVDPRHIQLLGDVMTYKGEVLGITRFGLSKMRDSVLQLASFEKT 1392
Query: 345 VQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKL 382
HLF+AA + D + GV E +++GQ + +GTG K+
Sbjct: 1393 TDHLFDAAFYMKKDAVEGVSECIILGQTMSIGTGSFKV 1430
>pir||T29959 DNA-directed RNA polymerase II large subunit ama-1 - Caenorhabditis
elegans >gi|1255805|gb|AAA96158.1| (U53333) C. elegans
DNA-directed RNA polymerase II large subunit (ama-1)
(SP:P16356) [Caenorhabditis elegans]
Length = 1862
Score = 202 bits (509), Expect = 5e-51
Identities = 139/417 (33%), Positives = 210/417 (50%), Gaps = 68/417 (16%)
Query: 36 KYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEIN 95
K KL + ++ E+ +++A+ +PGE VG +AAQS+GEP+TQMTLNTFHYAGV+ N
Sbjct: 1057 KSKLNSEAFDWLLGEIESRFQQAIAQPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKN 1116
Query: 96 VTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT--- 152
VTLG+PR+ EI++ K TP +TV+L D EKA++V ++E TTL+ + T
Sbjct: 1117 VTLGVPRLKEIINVSKTLKTPSLTVFLTGAAAKDPEKAKDVLCKLEHTTLKKVTCNTAIY 1176
Query: 153 -------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKKLQ 185
T+ + E++ +E+D +R+ LTME + ++
Sbjct: 1177 YDPDPKNTVIAEDEEWVSIFYEMPDHDLSRTSPWLLRIELDRKRMVDKKLTMEMIADRIH 1236
Query: 186 SSF----------KSAE---------FEMEGYTLIVRPKKFEKISDLRRL-AEKVKKHRL 225
F +AE E +G + K E LR + A + L
Sbjct: 1237 GGFGNDVHTIYTDDNAEKLVFRLRIAGEDKGEAQEEQVDKMEDDVFLRCIEANMLSDLTL 1296
Query: 226 KGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPTRTK 267
+G+ + K I+ EG ++++ T+G+ +VL +DP RT
Sbjct: 1297 QGIPAISKVYMNQPNTDDKKRIIITPEGGFKSVADWILETDGTALLRVLSERQIDPVRTT 1356
Query: 268 TNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHG 327
+N+I EI EVLGIEA R AI E+ N + G V+ RH+ L+ D+MT G + I RHG
Sbjct: 1357 SNDICEIFEVLGIEAVRKAIEREMDNVISFDGSYVNYRHLALLCDVMTAKGHLMAITRHG 1416
Query: 328 VVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
+ ++ L R +FE TV L EAA E D + GV EN+++GQ GTG L +
Sbjct: 1417 INRQEVGALMRCSFEETVDILMEAAVHAEEDPVKGVSENIMLGQLARCGTGCFDLVL 1473
>pir||S14183 DNA-directed RNA polymerase (EC 2.7.7.6) largest chain (isoform C)
- soybean (fragment) >gi|18736|emb|CAA36736.1| (X52495)
DNA-directed RNA polymerase [Glycine max]
Length = 977
Score = 200 bits (503), Expect = 2e-50
Identities = 133/412 (32%), Positives = 215/412 (51%), Gaps = 64/412 (15%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+Y+L++ E ++ E+ + ++LV PGE +G VAAQSIGEP+TQMTLNTFH+AGV+
Sbjct: 244 EEYRLSRESFEWVVGEIESRFLQSLVVPGEMIGVVAAQSIGEPATQMTLNTFHFAGVSAK 303
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT-- 152
NVTLG+PR+ E+++ K+ TP ++VYL + +E+A+ V +E TTL ++ + T
Sbjct: 304 NVTLGVPRLRELINVAKSIKTPSLSVYLKPDAGKTKERAKTVQCALEYTTLRSVTQATEV 363
Query: 153 -----------------------------TLDLINMEFI-VEIDPERLEKSGLTMEKVLK 182
L+ I+ F+ VE++ E + L+M + +
Sbjct: 364 WYDPDPMSTIIEEDVDFVMSYYEMPDEEVALEKISPWFVRVELNREMMVDKKLSMADIAQ 423
Query: 183 KLQSSFK---SAEF-EMEGYTLIVR--------PK---KFEKISD---LRRL-AEKVKKH 223
K+ F S F + LI+R PK + E D L+++ + +
Sbjct: 424 KINLEFDDDLSCIFNDDNAEKLILRIRIMNDDAPKGEVQDESAEDDVFLKKIETNMLTEM 483
Query: 224 RLKGLSGVGKTIVR-------------KEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNN 270
L+G+ + K ++ K E+++ TEG N V+ VD TRT +N+
Sbjct: 484 TLRGIPDINKVFIKNAKVQKFDENEGFKSNGEWMLDTEGVNLLAVMCHEDVDATRTTSNH 543
Query: 271 IHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVG 330
+ E+ EVLGIEA R ++++E+ + G V+ RH+ ++ + MT G + I RHG+
Sbjct: 544 LIEVIEVLGIEAVRRSLLDELRIVISFDGSYVNYRHLAILCETMTYRGHLMAITRHGINR 603
Query: 331 EKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKL 382
+ R +FE TV L +AA E D+L GV EN+++GQ P+GTG L
Sbjct: 604 NDTGPMMRCSFEETVDILLDAAAYAETDSLRGVTENIILGQLAPIGTGQCAL 655
>pir||T31436 DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain - Nosema
locustae >gi|4092885|gb|AAD12605.1| (AF061288) RNA
polymerase II largest subunit [Nosema locustae]
Length = 1553
Score = 199 bits (502), Expect = 3e-50
Identities = 132/387 (34%), Positives = 206/387 (53%), Gaps = 43/387 (11%)
Query: 31 IKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAG 90
IK Y+++ VE I +E+ K++ R ++ E VGT+AAQSIGEP+TQMTLNTFHYAG
Sbjct: 992 IKKVINYRISTLGVEWIANEIKKKFVRGIISTNEMVGTLAAQSIGEPATQMTLNTFHYAG 1051
Query: 91 VAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIE--------- 141
VA+ +T G+PR+ EI++ KN TP +YL E+A++VA IE
Sbjct: 1052 VAQA-ITQGVPRLKEIINVAKNIRTPSHKIYLKPGSTI--EQAKKVASEIEYINIEMVCS 1108
Query: 142 ----------GTTLENLART------------TTLDLINMEFI-VEIDPERLEKSGLTME 178
TT+ N R +LD +N + + + +RL + L E
Sbjct: 1109 EIKIIYDPKVDTTIINEDRDFVEAYFEFPDEYVSLDTLNPWLLRLVVARDRLISNNLDFE 1168
Query: 179 KVLKKLQSSFKSAEF----EMEGYTLIVRPKKFEKISD---LRRLAEKVKKHRLKGLSGV 231
+ +K++ F F + L++R + ++ RRL + LKG++ +
Sbjct: 1169 FIAQKIKKVFHQDIFLLHSDANAEELVIRIRVLGMSANEEFYRRLLNTILGIHLKGITNI 1228
Query: 232 GKTIVRKEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEI 291
+ + +E +E+++ T+G N KQ+L V + + N++ E+ EVLGIEA R I+ E+
Sbjct: 1229 RRIYLLREREEWILQTDGKNLKQLLLVEDILANKVYCNDLLEVYEVLGIEAVRECILREL 1288
Query: 292 MNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEA 351
N + +G V+ RH+ L+ D+MTL G +R I RHG L R +FE TV+ L EA
Sbjct: 1289 RNVIEAEGSYVNFRHLYLLCDVMTLKG-LRGITRHGANRAATGALKRCSFEETVEILLEA 1347
Query: 352 AERGEVDNLSGVIENVLIGQPVPVGTG 378
+ E + GV EN+++GQ P+GTG
Sbjct: 1348 SCFAERNYCRGVTENIMLGQLAPIGTG 1374
>pir||T31435 DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain -
Vairimorpha necatrix >gi|4001824|gb|AAD12604.1|
(AF060234) largest subunit of RNA polymerase II; RPO21
[Vairimorpha necatrix]
Length = 1605
Score = 197 bits (496), Expect = 2e-49
Identities = 143/449 (31%), Positives = 229/449 (50%), Gaps = 64/449 (14%)
Query: 6 TIKSLIEKKGKDLPESVKQELYEKLIKYN-------EKYKLTKAEVETIIDEVVKEYERA 58
T+K+LIE +LP +K L E LIKYN +YKL+ I+ E+ + ++
Sbjct: 988 TLKNLIE----NLP--IKNLLIEILIKYNLSIKRILNEYKLSLEAYNWILKEIKFKILKS 1041
Query: 59 LVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMM 118
++ P E VGT+AAQS+GEP+TQMTLNTFH AGV+ N+T+G+PR+ EI++ KN TP M
Sbjct: 1042 IISPNEMVGTLAAQSVGEPATQMTLNTFHLAGVSA-NITMGVPRLKEIINVAKNIKTPCM 1100
Query: 119 TVYLDEEHRYDREKAEEVARRIEGTTLENLARTTT------------------------- 153
+YL + E A+++ +E + +++L +
Sbjct: 1101 KIYLKDPFNKTLEMAKKIQSELEFSDIKSLCEFSEIYYDPVIEDTSIKEDKDFVQEYFDF 1160
Query: 154 ----LDLINM-EFIV--EIDPERLEKSGLTMEKVLKKLQSSFKSA----EFEMEGYTLIV 202
LD M +FI+ +ID +L L +E ++K L +F + + LI+
Sbjct: 1161 PDEHLDFSKMPKFIIRLKIDRIKLVSKNLKLENIVKSLHEAFPNIFHIIRSDENSQNLII 1220
Query: 203 RPKKFEKISD----LRRLAEKVKKHRLKGLSGVGKTIVR--KEGDEYVIYTEGSNFKQVL 256
R + +++ + + ++ G + + K + K+ DE+ + T+G +++
Sbjct: 1221 RIRCISSLNNNVEYYNLQYKNILNLKIMGYNKIKKVFISEDKDKDEWYLQTDGVCIREIF 1280
Query: 257 KVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTL 316
P V+ +N+++EI EVLGIEAAR I+ E+ + G V+ RHI L+AD+MT+
Sbjct: 1281 SHPNVEGHLVTSNDLNEIVEVLGIEAARETILNELTLVIDGNGSYVNHRHISLLADVMTM 1340
Query: 317 DGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVG 376
G + I RHGV RA+FE TV L +AA E G EN+++G P+G
Sbjct: 1341 KGYLTGITRHGVNKVGFGCTKRASFEETVDILLDAALVAEKYVTKGYTENIMMGHLAPLG 1400
Query: 377 TG-------MVKLTMKLPL-RPQKEKEEV 397
TG + KL +PL +P+ EEV
Sbjct: 1401 TGIGNLLLDVSKLDKAIPLSKPEYNYEEV 1429
>sp|P16356|RPB1_CAEEL DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT >gi|102468|pir||A34092
DNA-directed RNA polymerase (EC 2.7.7.6) II large chain -
Caenorhabditis elegans >gi|156405|gb|AAA28126.1| (M29235)
RNA polymerase II [Caenorhabditis elegans]
Length = 1859
Score = 197 bits (496), Expect = 2e-49
Identities = 138/419 (32%), Positives = 207/419 (48%), Gaps = 75/419 (17%)
Query: 36 KYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEIN 95
K KL + ++ E+ +++A+ +PGE VG +AAQS+GEP+TQMTLNTFHYAGV+ N
Sbjct: 1057 KSKLNSEAFDWLLGEIESRFQQAIAQPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKN 1116
Query: 96 VTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTL---------- 145
VTLG+PR+ EI++ K TP +TV+L D EKA++V ++E TT+
Sbjct: 1117 VTLGVPRLKEIINVSKTLKTPSLTVFLTGAAAKDPEKAKDVLCKLEHTTVTCNTAIYYDP 1176
Query: 146 ----------------------ENLARTTTLDLINMEFIVEIDPERLEKSGLTMEKVLKK 183
+L+RT+ L +E+D +R+ LTME + +
Sbjct: 1177 DPKNTVIAEDEEWVSIFYEMPDHDLSRTSPWLL-----RIELDRKRMVDKKLTMEMIADR 1231
Query: 184 LQSSF----------KSAE---------FEMEGYTLIVRPKKFEKISDLRRL-AEKVKKH 223
+ F +AE E +G + K E LR + A +
Sbjct: 1232 IHGGFGNDVHTIYTDDNAEKLVFRLRIAGEDKGEAQEEQVDKMEDDVFLRCIEANMLSDL 1291
Query: 224 RLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPTR 265
L+G+ + K I+ EG ++++ T+G+ +VL +DP R
Sbjct: 1292 TLQGIPAISKVYMNQPNTDDKKRIIITPEGGFKSVADWILETDGTALLRVLSERQIDPVR 1351
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N+I EI EVLGIEA R AI E+ N + G V+ RH+ L+ D+MT G + R
Sbjct: 1352 TTSNDICEIFEVLGIEAVRKAIEREMDNVISFDGSYVNYRHLALLCDVMTAKGHLMAYSR 1411
Query: 326 HGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
HG+ ++ L R +FE TV L EAA E D + GV EN+++GQ GTG L +
Sbjct: 1412 HGINRQEVGALMRCSFEETVDILMEAAVHAEEDPVKGVSENIMLGQLARCGTGCFDLVL 1470
>gb|AAA30233.1| (M27163) RNA polymerase III [Trypanosoma brucei]
Length = 1530
Score = 197 bits (495), Expect = 2e-49
Identities = 131/407 (32%), Positives = 210/407 (51%), Gaps = 37/407 (9%)
Query: 1 MVSSSTIKSLIEKKGKDLPESVK-QELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERAL 59
+ + T K K KD E + EL + + E LT+ V I + +Y R
Sbjct: 1079 IANKRTKKRAPSLKVKDSKEGGRVSELRDLEMLQTELLPLTRGMVTRFIAQCASKYLRKA 1138
Query: 60 VEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMT 119
EPG G +AAQS+GEPSTQMTL TFH+AGVA +++T G+PR++E+++A +N +TP++T
Sbjct: 1139 CEPGTPCGAIAAQSVGEPSTQMTLRTFHFAGVASMSITQGVPRLVEVINANRNIATPVVT 1198
Query: 120 VYL-----DEEH--------RYDREKAEEVARRIEGTTLENLARTTTLDL---INMEFI- 162
+ +E H R+ + + E V R + + + T L +NM I
Sbjct: 1199 APVLLMEGEENHCEIFRKRARFVKAQIERVLLREVVSEIVEVCSDTEFYLRVHLNMSVIT 1258
Query: 163 --------VEIDPERLEKSGLTMEKVLKKLQSSFKSAEFEMEGYTLIVRPKKFEKIS--- 211
+ + L +G TM + + + + TL V P F+
Sbjct: 1259 KLHLPINAITVRQRILAAAGHTMSPLRMLNEDCIEVFSLD----TLAVYPH-FQDARWVH 1313
Query: 212 -DLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNN 270
LRR+ + + + G+ G+ + ++ G E + EG+ + V+ + GVD TR N+
Sbjct: 1314 FSLRRILGLLPEVVVGGIGGINRAMISSNGTE--VLAEGAELRAVMNLWGVDSTRVVCNH 1371
Query: 271 IHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVG 330
+ + VLGIEAAR I++EI N ++ L +D+RH+ L+AD+MT GVV I R+G+
Sbjct: 1372 VAVVERVLGIEAARRVIVDEIQNILKAYSLSIDVRHVYLLADLMTQRGVVLGITRYGIQK 1431
Query: 331 EKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGT 377
+VL A+FE T HL+ AA VD V +++++G+PVP+GT
Sbjct: 1432 MNFNVLTMASFERTTDHLYNAAATQRVDRDLSVSDSIIVGKPVPLGT 1478
>sp|P08968|RPC1_TRYBB DNA-DIRECTED RNA POLYMERASE III LARGEST SUBUNIT >gi|84048|pir||S01393
DNA-directed RNA polymerase (EC 2.7.7.6) III 170K chain -
Trypanosoma brucei brucei >gi|10524|emb|CAA31014.1|
(X12494) RNA polymerase III largest subunit (AA 1 - 1530)
[Trypanosoma brucei]
Length = 1530
Score = 196 bits (493), Expect = 4e-49
Identities = 131/407 (32%), Positives = 209/407 (51%), Gaps = 37/407 (9%)
Query: 1 MVSSSTIKSLIEKKGKDLPESVK-QELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERAL 59
+ + T K K KD E + EL + + E LT+ V I + +Y R
Sbjct: 1079 IANKRTKKRAPSLKVKDSKEGGRVSELRDLEMLQTELLPLTRGMVTRFIAQCASKYLRKA 1138
Query: 60 VEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMT 119
EPG G +AAQS+GEPSTQMTL TFH+AGVA +++T G+PR++E+++A +N +TP++T
Sbjct: 1139 CEPGTPCGAIAAQSVGEPSTQMTLRTFHFAGVASMSITQGVPRLVEVINANRNIATPVVT 1198
Query: 120 VYL-----DEEH--------RYDREKAEEVARRIEGTTLENLARTTTLDL---INMEFI- 162
+ +E H R+ + + E V R + + + T L +NM I
Sbjct: 1199 APVLLMEGEENHCEIFRKRARFVKAQIERVLLREVVSEIVEVCSDTEFYLRVHLNMSVIT 1258
Query: 163 --------VEIDPERLEKSGLTMEKVLKKLQSSFKSAEFEMEGYTLIVRPKKFEKIS--- 211
+ + L +G TM + + + + TL V P F+
Sbjct: 1259 KLHLPINAITVRQRILAAAGHTMSPLRMLNEDCIEVFSLD----TLAVYPH-FQDARWVH 1313
Query: 212 -DLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNN 270
LRR+ + + G+ G+ + ++ G E + EG+ + V+ + GVD TR N+
Sbjct: 1314 FSLRRILGLLPDVVVGGIGGINRAMISSNGTE--VLAEGAELRAVMNLWGVDSTRVVCNH 1371
Query: 271 IHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVG 330
+ + VLGIEAAR I++EI N ++ L +D+RH+ L+AD+MT GVV I R+G+
Sbjct: 1372 VAVVERVLGIEAARRVIVDEIQNILKAYSLSIDVRHVYLLADLMTQRGVVLGITRYGIQK 1431
Query: 331 EKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGT 377
+VL A+FE T HL+ AA VD V +++++G+PVP+GT
Sbjct: 1432 MNFNVLTMASFERTTDHLYNAAATQRVDRDLSVSDSIIVGKPVPLGT 1478
>pir||T43260 RNA polymerase (EC 2.7.7.-) II - Trichomonas vaginalis
>gi|1143740|gb|AAB50025.1| (U20501) RNA polymerase II
[Trichomonas vaginalis]
Length = 1661
Score = 196 bits (492), Expect = 5e-49
Identities = 133/455 (29%), Positives = 227/455 (49%), Gaps = 71/455 (15%)
Query: 7 IKSLIEKKGKDLPESVKQE---LYEKLIKYNE--------KYKLTKAEVETIIDEVVKEY 55
+ SLI KG D +QE L +++ Y+ +Y+L + + I+ + +
Sbjct: 1014 VNSLIVVKGNDNISRTEQENATLLLRIMLYSHLSAKQCIFEYRLNEQAFKYILGSIKDRF 1073
Query: 56 ERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPST 115
R++V PGE VGT+A QSIGEPSTQMTLNTFH+AG++ +VTLG+PR+ E+++ K+ T
Sbjct: 1074 YRSIVAPGEMVGTIAGQSIGEPSTQMTLNTFHFAGISAHDVTLGVPRLNELMNLAKHIRT 1133
Query: 116 PMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL--------------------- 154
P +TV + + D E + V +IE + + +
Sbjct: 1134 PSVTVEFERDVAKDEEIVKAVRAQIESASFKKFVIKAEIYYDPNPEETIIEPDTKWINTR 1193
Query: 155 ------------DLINMEFIVEIDPERLEKSGL-TMEKVLKKLQSSFKSAEFEM-EGYTL 200
DL EI+ E + S + ++ +++K++ + F + +
Sbjct: 1194 IRYGGVEDRELQDLAPWVLRFEINREEMIASNIESISDIVQKIKGMYGDKFFVIGDDDAR 1253
Query: 201 IVR------PKKFEKISDLRRLAEK----VKKHRLKGLSGVGKTIVRKEGDEYVI----- 245
I+R ++ E D++ L E K LKG+ G+ + + ++ +
Sbjct: 1254 IIRMQARLKDEQAEFAMDVKFLRETEQQMYKSFTLKGIPGISRVKINSAAEKMFLNPETH 1313
Query: 246 ----------YTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTM 295
YTEG+ F+++L + VD T TN+I+++ +VLGIEAAR+++ E+M M
Sbjct: 1314 GFDKEKVSCLYTEGTAFREILSLDHVDTVHTITNDIYQVCDVLGIEAARHSLSYEMMLIM 1373
Query: 296 REQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERG 355
+ G ++ RH+ L+AD MT GV+ P+ RHG+ L RA++E+T F+AA
Sbjct: 1374 EKAGAALNRRHLDLLADTMTQYGVLYPVSRHGINKTPTGTLMRASYEMTNDVFFDAAVFS 1433
Query: 356 EVDNLSGVIENVLIGQPVPVGTGMVKLTMKLPLRP 390
E+D + V N++ G+P GTG+V++ + L P
Sbjct: 1434 EIDYMRDVSSNIIAGKPSRAGTGIVEVLINEDLLP 1468
>pir||T43217 RNA polymerase (EC 2.7.7.-) II, largest chain - Porphyra yezoensis
(fragment) >gi|3169691|gb|AAC17924.1| (U90208) RNA
polymerase II largest subunit [Porphyra yezoensis]
Length = 1685
Score = 191 bits (481), Expect = 9e-48
Identities = 136/440 (30%), Positives = 212/440 (47%), Gaps = 85/440 (19%)
Query: 22 VKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQM 81
V+ L K++ +++LT+ ++ E+ +++AL GE VG AAQSIGEP+TQM
Sbjct: 984 VRASLASKVVL--SEHRLTRKAFTWLLIEIENRFQQALAPAGEMVGATAAQSIGEPATQM 1041
Query: 82 TLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIE 141
TLNTFHYAGV+ NVTLG+PR+ EI++ K TP + VYL + +D E+A++V ++
Sbjct: 1042 TLNTFHYAGVSAKNVTLGVPRLQEIINVSKRTKTPSLVVYLRGDAVHDAERAKQVQAELQ 1101
Query: 142 GTTLENLARTTTL----DLINM----------------EFIVEIDP---------ERLEK 172
TTL ++ T + DL N + +V P + +
Sbjct: 1102 HTTLRHVTHMTEVYYDPDLENTIVPADEELVSAYYELPDDVVHASPWLLRLVLAKDMVVD 1161
Query: 173 SGLTMEKVLKKLQSSFKS----AEFEMEGYTLIVRPK-----------------KFEKIS 211
L M + ++ + F E L++R + +FE
Sbjct: 1162 RKLAMNTIKNRIHAHFGGDLHVMASEDNAAELVIRVRVAMENEDKAGISDSTKPRFEDEQ 1221
Query: 212 DLRRLA--------------EKVKKHRLKGLS-----GVGKTIVRKEG------------ 240
D R+A KV+ L L+ G+ K R++
Sbjct: 1222 DADRVAAEMEDEEDAEDLFLRKVESQLLSNLTLSGIPGIDKVFTRQDNKIVIDSVTGSFT 1281
Query: 241 --DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQ 298
+E+++ T+G NF V+ VD TRT +N+I E EVLGIEA R ++ EI +
Sbjct: 1282 KENEWLLETDGVNFIAVMGHEDVDFTRTVSNDIVETFEVLGIEAVRATLLNEIRTVISFD 1341
Query: 299 GLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVD 358
G V+ RH+ ++ D+MT G + I RHG+ +S L + +FE T L +AA GE D
Sbjct: 1342 GAYVNYRHLSVLVDVMTFRGHLMAISRHGINRVSSSALMKCSFEETSDILLDAAMHGETD 1401
Query: 359 NLSGVIENVLIGQPVPVGTG 378
L+GV E++++GQ P+GTG
Sbjct: 1402 TLTGVSESIMLGQLAPLGTG 1421
>pir||T43026 probable DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain -
Bonnemaisonia hamifera (fragment)
>gi|3172134|gb|AAC18416.1| (U90209) RNA polymerase II
largest subunit [Bonnemaisonia hamifera]
Length = 1732
Score = 191 bits (481), Expect = 9e-48
Identities = 137/424 (32%), Positives = 208/424 (48%), Gaps = 71/424 (16%)
Query: 32 KYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGV 91
K + ++LT ++ EV + V PGE +G +AAQSIGEP+TQMTLNTFHYAGV
Sbjct: 978 KLIQLHRLTFKAFLWLLGEVENRFMMCRVAPGENIGAIAAQSIGEPATQMTLNTFHYAGV 1037
Query: 92 AEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLART 151
+ NVTLG+PR+ EI++ KN TP +TVYL ++ D+EKA+E+ ++ TTL ++ +
Sbjct: 1038 SAKNVTLGVPRLKEIINVSKNTKTPSLTVYLKSQYAGDKEKAKEIQASLQHTTLHDVTQC 1097
Query: 152 TTL---------------DLINMEFIVE--------------IDPERLEKSGLTM----- 177
T + ++++ F +E +D + L+ ++M
Sbjct: 1098 TEIYYDPDPMDTVVDADREMVSSFFDLEEAPVGVSPWLLRIIMDKDMLQDRKISMDRIEN 1157
Query: 178 -------------------EKVLKKLQSSFKSAEFEM--EGYTLIVRPKKFEKISDLRRL 216
EK++ +L+ + +SA+ + EG I + R
Sbjct: 1158 MITQNFGNDVHVIRSQDNDEKMVMRLRVADESAQEKCGEEGGADIEEDDDEDSDDTFLRR 1217
Query: 217 AEK--VKKHRLKGLSGVGKTIVRKEGDEYV---IYTEGSNFKQVLKVPGV---------- 261
E + + L G+ + K +R+ +V T S + VL GV
Sbjct: 1218 LESELLSQMNLGGIPAIRKVFMRQSRFTFVDPGTGTHKSREEWVLDTDGVNLLAVMSHEA 1277
Query: 262 -DPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVV 320
D TRT +N+I EI EVLGIEA R ++ EI + G V+ RH+ ++ D MT G +
Sbjct: 1278 VDHTRTTSNDIVEIFEVLGIEAVREVLLNEIRGVISFDGAYVNYRHLAILVDTMTYRGHL 1337
Query: 321 RPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMV 380
I RHGV L + +FE T L EAA GE D L GV EN+++GQ P+GTG
Sbjct: 1338 MAITRHGVNRVDTGPLMKCSFEGTTDILLEAAMWGERDGLRGVTENIMLGQLAPIGTGSF 1397
Query: 381 KLTM 384
+L +
Sbjct: 1398 RLLL 1401
>pir||S22812 DNA-directed RNA polymerase (EC 2.7.7.6) III largest chain - Giardia
lamblia
Length = 1735
Score = 189 bits (474), Expect = 6e-47
Identities = 132/387 (34%), Positives = 203/387 (52%), Gaps = 43/387 (11%)
Query: 39 LTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTL 98
LTK +++ + +V ++Y R +EPG G VAAQS+GEPSTQMTL +FH+AG+A +N+T
Sbjct: 1267 LTKKDIDDFLRQVRRKYIRLNLEPGSPCGAVAAQSVGEPSTQMTLKSFHHAGLASMNITQ 1326
Query: 99 GLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIE-GTTLENLARTTTLDLI 157
G+PR+ EIVD STP+ TV L + + A + +E ++N+ T L I
Sbjct: 1327 GVPRLKEIVDGVVKISTPITTVELHVDVDKEELAATVTEKYLEKARMMKNIIECTYLGQI 1386
Query: 158 NMEFI-----------VEIDPERLEKSGL----TMEKVLKKLQSSFKSAEF----EMEGY 198
+ I V +D + + GL T+E V+ + + K+ + + G
Sbjct: 1387 SASIIECYSQSVCHIEVNLDMKIIADMGLAGIITVETVVASILHNDKAKKLVGQDQSSGS 1446
Query: 199 TLI-------VRP---KKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGD------- 241
I VRP + + + D++ L + + G+S + ++ + +
Sbjct: 1447 VSIHSATRFSVRPLTQSRDDLLFDIQSLKLLLPMIPVSGISTCSRAVINEYKEFCQGATS 1506
Query: 242 -----EYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMR 296
+Y + EG + +L V G+D TRT +NNI E+A LGIEAA I EI M
Sbjct: 1507 SAPLTKYNLLVEGIGLQNILNVSGIDFTRTLSNNIVEVANTLGIEAAVATISNEIKACMD 1566
Query: 297 EQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKA-SVLARAAFEITVQHLFEAAERG 355
G+ VD+RHI L+ADIM G V R G+ KA SV+ A+FE T +HLF AA
Sbjct: 1567 SHGMAVDMRHIRLLADIMCFRGRVLGFTRFGLTKMKADSVIMLASFEKTGEHLFNAALGN 1626
Query: 356 EVDNLSGVIENVLIGQPVPVGTGMVKL 382
+VD +GV E++++G+P+ +GTG L
Sbjct: 1627 KVDEANGVTESIILGKPMSMGTGSFSL 1653
>sp|P25202|RPC1_GIALA DNA-DIRECTED RNA POLYMERASE III LARGEST SUBUNIT
>gi|9364|emb|CAA42895.1| (X60325) subunit A of DNA
dependent RNA polymerase III [Giardia intestinalis]
Length = 1741
Score = 189 bits (474), Expect = 6e-47
Identities = 132/387 (34%), Positives = 203/387 (52%), Gaps = 43/387 (11%)
Query: 39 LTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTL 98
LTK +++ + +V ++Y R +EPG G VAAQS+GEPSTQMTL +FH+AG+A +N+T
Sbjct: 1267 LTKKDIDDFLRQVRRKYIRLNLEPGSPCGAVAAQSVGEPSTQMTLKSFHHAGLASMNITQ 1326
Query: 99 GLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIE-GTTLENLARTTTLDLI 157
G+PR+ EIVD STP+ TV L + + A + +E ++N+ T L I
Sbjct: 1327 GVPRLKEIVDGVVKISTPITTVELHVDVDKEELAATVTEKYLEKARMMKNIIECTYLGQI 1386
Query: 158 NMEFI-----------VEIDPERLEKSGL----TMEKVLKKLQSSFKSAEF----EMEGY 198
+ I V +D + + GL T+E V+ + + K+ + + G
Sbjct: 1387 SASIIECYSQSVCHIEVNLDMKIIADMGLAGIITVETVVASILHNDKAKKLVGQDQSSGS 1446
Query: 199 TLI-------VRP---KKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGD------- 241
I VRP + + + D++ L + + G+S + ++ + +
Sbjct: 1447 VSIHSATRFSVRPLTQSRDDLLFDIQSLKLLLPMIPVSGISTCSRAVINEYKEFCQGATS 1506
Query: 242 -----EYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMR 296
+Y + EG + +L V G+D TRT +NNI E+A LGIEAA I EI M
Sbjct: 1507 SAPLTKYNLLVEGIGLQNILNVSGIDFTRTLSNNIVEVANTLGIEAAVATISNEIKACMD 1566
Query: 297 EQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKA-SVLARAAFEITVQHLFEAAERG 355
G+ VD+RHI L+ADIM G V R G+ KA SV+ A+FE T +HLF AA
Sbjct: 1567 SHGMAVDMRHIRLLADIMCFRGRVLGFTRFGLTKMKADSVIMLASFEKTGEHLFNAALGN 1626
Query: 356 EVDNLSGVIENVLIGQPVPVGTGMVKL 382
+VD +GV E++++G+P+ +GTG L
Sbjct: 1627 KVDEANGVTESIILGKPMSMGTGSFSL 1653
>gb|AAB51212.1| (U73456) large subunit RNA polymerase II [Teratorhabditis palmarum]
Length = 631
Score = 182 bits (456), Expect = 8e-45
Identities = 119/369 (32%), Positives = 187/369 (50%), Gaps = 67/369 (18%)
Query: 37 YKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINV 96
+KL + ++ E+ +++A+ +PGE VG +AAQS+GEP+TQMTLNTFH+AGV+ NV
Sbjct: 263 HKLNNEAFDWLLGEIEHRFKQAIAQPGEMVGALAAQSLGEPATQMTLNTFHFAGVSAKNV 322
Query: 97 TLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT---- 152
TLG+PR+ EI++ K P TP +T+YL D E+A+EV R+E TTL + T
Sbjct: 323 TLGVPRLKEIINVSKKPKTPSLTIYLTGAAARDAERAKEVQCRLEHTTLRKVTSNTAIYY 382
Query: 153 ------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKKLQS 186
T+ + E++ +E+D +R+ LTME + ++
Sbjct: 383 DPDPRNTIIQEDEEWVAFYYEMPDSLPSNVSPWLLRIELDRKRMTDKRLTMEAIASRITQ 442
Query: 187 SF----KSAEFEMEGYTLIVRPK-KFEKISDLRRLAEKVK--------------KHRLKG 227
F + + +L+ R + + E D EK++ + L+G
Sbjct: 443 GFGYDLHTIYTDDNADSLVFRIRIRSENKGDTEETIEKMEDDMFLRAVEQICLLELTLQG 502
Query: 228 LSGVGK-------------TIVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPTRTKTN 269
+ + K T++ EGD E+++ T+G++ VL P VDP RT +N
Sbjct: 503 IEQISKVYMHKPTTDDKKRTVITPEGDFRSIAEWLLETDGTSLLDVLSQPNVDPVRTYSN 562
Query: 270 NIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVV 329
+I EI EVLGIEA R AI E+ + G V+ RH+ L+ D+MT G + I RHG+
Sbjct: 563 DICEIFEVLGIEAVRKAIEREMHQVISFDGSYVNYRHLALLCDVMTAKGHLMAITRHGIN 622
Query: 330 GEKASVLAR 338
++ L R
Sbjct: 623 RQEVGALMR 631
>gb|AAB51211.1| (U73454) large subunit RNA polymerase II [Mesorhabditis sp.]
Length = 633
Score = 181 bits (455), Expect = 1e-44
Identities = 119/373 (31%), Positives = 190/373 (50%), Gaps = 69/373 (18%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
EKY+L + E ++ E+ +++A+ +PGE VG +AAQS+GEP+TQMTLNTFH+AGV+
Sbjct: 261 EKYRLNQEGFEWLLGEIEHRFQQAIAQPGEMVGALAAQSLGEPATQMTLNTFHFAGVSAK 320
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ EI++ K+P TP +TV+L R D EKA++V ++E TTL + T +
Sbjct: 321 NVTLGVPRLKEIINVSKSPKTPSLTVFLTGAARKDAEKAKDVLCKLEHTTLRKVTANTAI 380
Query: 155 ---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVLKKL 184
+ + M + +E+D +R+ L+ME + +++
Sbjct: 381 YYDPDPKNTVIEEDEEWVAMFYEMPDFDPSRCSPWLLRIELDRKRMIDKKLSMEAISERI 440
Query: 185 QSSFKS------AEFEMEGYTLIVR-----------PKKFEKISD---LRRLAEKVKKH- 223
Q SF + + +R ++ +++ D LR L + +
Sbjct: 441 QQSFGETLNVIYTDDNADNLVFRIRIVADDQDKGDTEEQVDRMEDDAFLRALEQNMLSDL 500
Query: 224 RLKGLSGVGKTIVRKEG------------------DEYVIYTEGSNFKQVLKVPGVDPTR 265
L+G+ + K + K E+++ T+G+ QVL P VDP R
Sbjct: 501 TLQGIEQITKVYMHKPTTDDKKRIVITPEAGFKAIPEWLLETDGTALLQVLSQPNVDPIR 560
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N+I EI EVLGIEA R AI E+ + G V+ RH+ L+ D+MT G + I R
Sbjct: 561 TTSNDICEIFEVLGIEAVRKAIEREMHQVISFDGSYVNYRHLALLCDVMTAKGHLMAITR 620
Query: 326 HGVVGEKASVLAR 338
HG+ ++ L R
Sbjct: 621 HGINRQEVGALMR 633
>gb|AAA50225.1| (U10334) RNA polymerase II, largest subunit [Crassostrea gigas]
Length = 1340
Score = 181 bits (455), Expect = 1e-44
Identities = 123/379 (32%), Positives = 191/379 (49%), Gaps = 74/379 (19%)
Query: 32 KYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGV 91
+ E+++L+ E +I EV +++A PGE VG +AAQS+GEP+TQMTLNTFHYAGV
Sbjct: 964 RVTEEFRLSSEAFEWLIGEVESRFQQAQAHPGEMVGALAAQSLGEPATQMTLNTFHYAGV 1023
Query: 92 AEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLART 151
+ NVTLG+PR+ EI++ K P TP +TVYL + D EKA++V R+E TTL +
Sbjct: 1024 SAKNVTLGVPRLKEIINISKKPKTPSLTVYLIGQAARDAEKAKDVLCRLEHTTLRKVTAN 1083
Query: 152 TTL---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVL 181
T + + +N+ + +E+D +R+ LTME++
Sbjct: 1084 TAIYYDPDPQNTVISEDQEWVNVYYEMPDFDVSKISAWLLRIELDRKRMTDKKLTMEQIS 1143
Query: 182 KKLQSSF-----------------------KSAEFEMEGYTLIVRPKKFEKISDLRRL-A 217
+K+ + F S E +M+ IV K E LR + A
Sbjct: 1144 EKITAGFGDDLNCIFNDDNAEKLVLRIRIMNSDESKMQNEEEIV--DKMEDDVFLRCIEA 1201
Query: 218 EKVKKHRLKGLSGVGKTI-------------VRKEGD-----EYVIYTEGSNFKQVLKVP 259
+ L+G+ + K + +EG+ E+++ T+G+ +VL
Sbjct: 1202 NLLSDMTLQGIEAIAKVYMHLPNTEDKKRISITEEGEFKAVAEWILETDGTALMKVLSQR 1261
Query: 260 GVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGV 319
VDP RT TN+I E+ +LGIEA R +I +E+ + + G V+ RH+ L+ D MT G
Sbjct: 1262 DVDPIRTTTNDIVEVFSILGIEAVRKSIEKEMNHVISFDGSYVNYRHLSLLCDSMTAKGH 1321
Query: 320 VRPIGRHGVVGEKASVLAR 338
+ I RHG+ ++ LAR
Sbjct: 1322 LMAITRHGINRQETGALAR 1340
>gb|AAA50229.1| (U10338) RNA polymerase II, largest subunit [Ilyanassa obsoleta]
Length = 1343
Score = 181 bits (454), Expect = 1e-44
Identities = 118/374 (31%), Positives = 189/374 (49%), Gaps = 70/374 (18%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+++L++ ++ E+ +++A PGE VG +AAQS+GEP+TQMTLNTFHYAGV+
Sbjct: 970 EEHRLSEDAFNWLLGEIETRFQQAQAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAK 1029
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ EI++ K P TP +TVYL+ D EK ++V R+E TTL + T +
Sbjct: 1030 NVTLGVPRLKEIINISKKPKTPSLTVYLNGPAARDAEKCKDVLCRLEHTTLRKVTANTAI 1089
Query: 155 ----DLINMEFI--------------------------VEIDPERLEKSGLTMEKVLKKL 184
D +N + +E+D +R+ LTME++ +K+
Sbjct: 1090 YYDPDPMNTVIVEDQEWVSIYYEMPDFDASRISPWLLRIELDRKRMTDKKLTMEQISEKI 1149
Query: 185 QSSFKS------AEFEMEGYTLIVRPKKFE--KISDLRRLAEKVKKH------------- 223
+ F + E L +R + K+ D + +K++
Sbjct: 1150 TAGFGDDLNCIFNDDNAEKLVLRIRIMNSDDSKMQDEEEVVDKMEDDVFLRCIESNLLSD 1209
Query: 224 -RLKGLSGVGKTI-------------VRKEGD-----EYVIYTEGSNFKQVLKVPGVDPT 264
L+G+ + K + +EG+ E+++ T+GS+ +VL VDP
Sbjct: 1210 MTLQGIEAIAKVYMHLPTTDDKKRIHITEEGEFKAVAEWILETDGSSLMKVLSERDVDPV 1269
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT TN+I E+ LGIEA R AI E+++ + G V+ RH+ L+ D+MT G + I
Sbjct: 1270 RTYTNDIVEVFATLGIEAVRKAIEREMVHVISFDGSYVNYRHLALLCDVMTAKGHLMAIT 1329
Query: 325 RHGVVGEKASVLAR 338
RHG+ ++ LAR
Sbjct: 1330 RHGINRQETGALAR 1343
>gb|AAA50227.1| (U10336) RNA polymerase II, largest subunit [Helobdella stagnalis]
Length = 1337
Score = 178 bits (448), Expect = 7e-44
Identities = 121/375 (32%), Positives = 197/375 (52%), Gaps = 71/375 (18%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E++ L+ E ++ E+ ++ +A V+PGE VG +AAQS+GEP+TQMTLNTFHYAGV+
Sbjct: 963 EEFHLSTEAFEWLMGEIESKFIQARVQPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAK 1022
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT-- 152
NVTLG+PR+ EI++ K P P +TV L + D EKA++V ++E TTL + T
Sbjct: 1023 NVTLGVPRLKEIINVSKKPRAPSLTVILIGQPARDAEKAKDVLCQLEHTTLRKVTENTAI 1082
Query: 153 --------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKKL 184
TL + E++ VE+D +R+ LTME++ +K+
Sbjct: 1083 YYDPDPMHTLIEEDQEWVYIYYDMPDVDISRLSPWLLRVELDRKRMTDKKLTMEQISEKI 1142
Query: 185 QSSFKS------AEFEMEGYTLIVR-------------PKKFEKISD---LRRL-AEKVK 221
+ F + E L VR ++ +K+ D L+ + + +
Sbjct: 1143 TAGFGDDLNCIFNDDNAEKLVLRVRLMSNQDGKQDQDTEEQIDKMPDDTFLKHIESNMLT 1202
Query: 222 KHRLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDP 263
L+G++ + K I+ ++G+ ++++ T+G+ ++VL V VDP
Sbjct: 1203 DMTLQGITSIAKVYMQQPTTDDKKRIIIDEKGEFKALQDWILETDGTALRRVLSVENVDP 1262
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
+T +N+I E+ EVLGIEA R +I E+ N + G V+ RH+ L+ D+MT G + I
Sbjct: 1263 VKTVSNDIVEVFEVLGIEAVRKSIEREMNNVISFDGSYVNYRHLALLCDVMTAKGHLMAI 1322
Query: 324 GRHGVVGEKASVLAR 338
RHG+ ++ VLAR
Sbjct: 1323 TRHGINRQETGVLAR 1337
>gb|AAC83397.1| (U10331) RNA polymerase II, largest subunit [Artemia salina]
Length = 1341
Score = 174 bits (437), Expect = 1e-42
Identities = 119/374 (31%), Positives = 191/374 (50%), Gaps = 70/374 (18%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++Y+L E +I E+ ++ A PGE VG +AAQS+GEP+TQMTLNTFH+AGV+
Sbjct: 968 DEYRLNTEAFEWLIGEIETRFQLAQAVPGEMVGAIAAQSLGEPATQMTLNTFHFAGVSSK 1027
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ EI++ ++P P +TV+L D EKA++V R+E TTL+ + T +
Sbjct: 1028 NVTLGVPRLKEIINVSRSPKAPSLTVFLTGTAARDAEKAKQVLCRLEHTTLKKVTANTAI 1087
Query: 155 ----DLIN------MEFI--------------------VEIDPERLEKSGLTMEKVLKKL 184
D+ N +F+ +E+D +R+ LTME++ +K+
Sbjct: 1088 YYDPDIKNTVIAEDQDFVTLYYDMPDVDTSRMSPWLLRIELDRKRMTDKKLTMEQISEKI 1147
Query: 185 QSSFKS------AEFEMEGYTLIVR------------PKKFEKISD---LRRL-AEKVKK 222
+ F + E L +R ++ +K+ D LR + A +
Sbjct: 1148 TAGFGEDLNCIFNDDNAEKLVLRIRIMNSDESKFGEEDEQIDKMEDDMFLRCIEANMLSD 1207
Query: 223 HRLKGLSGVGKT-------------IVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPT 264
L+G+ + K I+ G+ E+++ T+G++ +VL VDP
Sbjct: 1208 MTLQGIEAISKVYMHLPQTDNKKRIIITDTGEFRAIAEWLLETDGTSLMKVLSERDVDPV 1267
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT +N+I EI VLGIEA R +I +E+ ++ GL V+ RH+ L+ D+MT G + I
Sbjct: 1268 RTYSNDICEIFTVLGIEAVRKSIEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGYLMAIT 1327
Query: 325 RHGVVGEKASVLAR 338
RHG+ + L R
Sbjct: 1328 RHGINRQDTGALMR 1341
>gb|AAB40621.1| (U61762) RNA polymerase II large subunit [Aduncospiculum halicti]
Length = 631
Score = 174 bits (436), Expect = 2e-42
Identities = 122/373 (32%), Positives = 184/373 (48%), Gaps = 71/373 (19%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
EK+KL E ++ E+ +++A+ +PGE VG +AAQS+GEP+TQMTLNTFHYAGV+
Sbjct: 261 EKHKLNAEAFEWLLGEIETRFQQAIAQPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAK 320
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR+ EI++ K P TP +TV+L+ D EKA++V ++E TTL + T +
Sbjct: 321 NVTLGVPRLKEIINVSKKPKTPSLTVFLEGAAAKDAEKAKDVLCKLEHTTLRKVTANTAI 380
Query: 155 ---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVLKKL 184
+ +++ + +E+D +R+ LTME + K+
Sbjct: 381 YYDPDPQSTCIEEDEEWVSIFYEMPDFDPSRASPWLLRLELDRKRMTDKKLTMEAIADKI 440
Query: 185 QSSF--------------------------KSAEFE----MEGYTLIVRPKKFEKISDLR 214
F K E E ME + +R + +SDL
Sbjct: 441 HHGFGDDLNVIYTDDNADKLVFRLRITNQDKGGEEEQVDKMED-DMFLRCIEANMLSDLT 499
Query: 215 ----RLAEKVKKHRLKGLSGVGKTIVRKEGD-----EYVIYTEGSNFKQVLKVPGVDPTR 265
KV H+ KTIV +G E+++ T+G+ +VL VD R
Sbjct: 500 LQGIEAISKVYMHK-PTTDDKKKTIVTPDGSFKAIPEWILETDGTALLKVLSEQNVDQHR 558
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N+I EI E+LGIEA R AI E+ + G V+ RH+ L+ D+MT G + I R
Sbjct: 559 TYSNDICEIFEILGIEAVRKAIEREMHQVISFDGSYVNYRHLALLCDVMTAKGHLMAITR 618
Query: 326 HGVVGEKASVLAR 338
HG+ ++ L R
Sbjct: 619 HGINRQEVGALMR 631
>gb|AAC47792.2| (AF009163) RNA polymerase II large subunit [Leishmania major]
Length = 1663
Score = 171 bits (429), Expect = 1e-41
Identities = 122/419 (29%), Positives = 209/419 (49%), Gaps = 68/419 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 1031 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 1090
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ T +
Sbjct: 1091 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANITTTVQI 1149
Query: 155 ---------------DLINME-------------------FIVE--IDPERLEKSGLTME 178
++I E FI +D + L M+
Sbjct: 1150 IYDPDPRNTVVAEDEEMIRWEQAVMNAEDEEPDAEQPPSPFIARLILDNDLFNDKRLNMK 1209
Query: 179 KV---LKKLQSSFK-SAEFEMEGYTLI-VRPKKFEKISD----LRRLAEKVKKHRLKGLS 229
V ++++ ++ A E +G ++ +RP+K + +A+ ++ L+G+
Sbjct: 1210 DVKSAIRQVDDTYMVQANMENDGQRIVRLRPRKCTGADSXPALTKAVAQLLQSVHLRGIP 1269
Query: 230 GVGKTIVR--------------KEGDEYVIYTEGSN----FKQVLKVPG---VDPTRTKT 268
G+ KT+++ K +++ TEG+ F V+ G +D ++T +
Sbjct: 1270 GIKKTLLKEGNTFRVDPEAGGIKNESSWMVDTEGTALQRIFVGVVNSEGKNIIDFSKTSS 1329
Query: 269 NNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGV 328
N I E+ VLGIEAAR ++ E+ GL ++ RH ++ D M G + + R G+
Sbjct: 1330 NKIPEVVTVLGIEAARRKMLSELREAYLAYGLNINYRHYTILVDTMCQRGYLMAVSRTGI 1389
Query: 329 -VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTMKL 386
E + L R +FE TV+ L AA GE D + GV ++++G +GTG+ L + +
Sbjct: 1390 NRSETSGPLMRCSFEETVKVLMTAAAFGEKDPVRGVSASLVLGNQARIGTGLFDLLLDM 1448
>gb|AAB40622.1| (U61763) RNA polymerase II large subunit [Zeldia punctata]
Length = 629
Score = 171 bits (429), Expect = 1e-41
Identities = 115/374 (30%), Positives = 178/374 (46%), Gaps = 76/374 (20%)
Query: 37 YKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINV 96
+KL E I+ E+ + +A+ +PGE VG +AAQS+GEP+TQMTLNTFHYAGV+ NV
Sbjct: 260 HKLNTEAFEWILGEIETRFNQAIAQPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNV 319
Query: 97 TLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT---- 152
TLG+PR+ EI++ K P TP +T++L + D E+A++V ++E TL + T
Sbjct: 320 TLGVPRLKEIINVSKRPKTPSLTIFLQGQAAKDAERAKDVLCKLEHCTLRKVTANTADYY 379
Query: 153 ------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKKLQS 186
T + E++ +E+D +R+ LTME + +K+
Sbjct: 380 DPDPKNTCIEEDQEWVQIFYEMPDFDPANASPWLLRLELDRKRMTDKKLTMEAIAEKIHK 439
Query: 187 SF------------------------KSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKK 222
F + + E E + F K + L++
Sbjct: 440 GFGEDLHVIYTDDNADKLVFHIRLTNSTTDKESEEQIDKMEDDTFLKCIESNMLSDLT-- 497
Query: 223 HRLKGLSGVGKTIVRKEG------------------DEYVIYTEGSNFKQVLKVPGVDPT 264
L+G+ + K + K E+++ T+G+ +VL P VDP
Sbjct: 498 --LQGIEAISKVYMHKPQTDDKKRVEVTQDGSFRMVSEWMLETDGTALLRVLSEPNVDPI 555
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
RT +N+I EI EVLGIEA R AI E+ + G V+ RH+ L+ D+MT G + I
Sbjct: 556 RTYSNDICEIFEVLGIEAVRKAIEREMNQVISFDGSYVNYRHLALLCDVMTAKGHLMAIT 615
Query: 325 RHGVVGEKASVLAR 338
RHG+ ++ L R
Sbjct: 616 RHGINRQEVGALMR 629
>gb|AAB51213.1| (U73448) large subunit RNA polymerase II [unidentified nematode]
Length = 633
Score = 170 bits (426), Expect = 3e-41
Identities = 119/370 (32%), Positives = 186/370 (50%), Gaps = 69/370 (18%)
Query: 38 KLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVT 97
KL + ++ E+ + +A+ +PGE VG +AAQS+GEP+TQMTLNTFHYAGV+ NVT
Sbjct: 264 KLNTEAFDWLLGEIESRFMQAIAQPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVT 323
Query: 98 LGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL--- 154
LG+PR+ EI++ K TP +TV+L D EKA++V ++E TTL+ + T +
Sbjct: 324 LGVPRLKEIINVSKQLKTPSLTVFLTGAAAKDAEKAKDVLCKLEHTTLKKVTANTAIYYD 383
Query: 155 -DLINM------EFI--------------------VEIDPERLEKSGLTMEKVLKKLQSS 187
D N E++ +E+D +R+ LTME + ++ S
Sbjct: 384 PDPKNTVIGEDEEWVSIFYEMPDFDTTRTSPWLLRIELDRKRMTDKNLTMEMIADRIHSG 443
Query: 188 F-------------KSAEFEM----EGYTLIVRPKKFEKISD---LRRL-AEKVKKHRLK 226
F + F + E + ++ +K+ D LR + A + L+
Sbjct: 444 FGQDVHTIYTDDNAEKLVFRLRIAGEDKAAEGQEEQVDKMEDDVFLRCIEANMLSDLTLQ 503
Query: 227 GLSGVGKT-------------IVRKEG-----DEYVIYTEGSNFKQVLKVPGVDPTRTKT 268
G+ + K I+ +EG E+++ T+G+ +VL +DP RT +
Sbjct: 504 GIPAISKVYMNQPNTDDKKRIIITEEGGFKSITEWILETDGTALLRVLSERQIDPVRTSS 563
Query: 269 NNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGV 328
N+I EI EVLGIEA R AI E+ N + G V+ RH+ L+ D+MT G + I RHG+
Sbjct: 564 NDICEIFEVLGIEAVRKAIEREMHNVISFDGSYVNYRHLALLCDVMTAKGHLMAITRHGI 623
Query: 329 VGEKASVLAR 338
++ L R
Sbjct: 624 NRQEVGALMR 633
>gb|AAF36438.1|AF126254_1 (AF126254) RNA polymerase II largest subunit [Leishmania donovani]
Length = 1595
Score = 169 bits (423), Expect = 6e-41
Identities = 121/419 (28%), Positives = 208/419 (48%), Gaps = 68/419 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+ +L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 1031 KEYKLNDKAFEYLLKEIRTKYQESLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 1090
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ T +
Sbjct: 1091 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANITTTVQI 1149
Query: 155 ---------------DLINME-------------------FIVE--IDPERLEKSGLTME 178
++I E FI +D + L M+
Sbjct: 1150 IYDPDPRNTVVAEDEEMIRWEQAVMNEEDEEPDAEQPPSPFIARLILDNDLFNDKRLNMK 1209
Query: 179 KV---LKKLQSSFK-SAEFEMEGYTLI-VRPKKFEKISDL----RRLAEKVKKHRLKGLS 229
V ++++ ++ A E +G ++ +RP+K + + +A+ ++ +G+
Sbjct: 1210 DVKSAIRQVDDTYMVQANMENDGQRIVRLRPRKCTGADSVPALTKAVAQLLQSVHHRGIP 1269
Query: 230 GVGKTIVR--------------KEGDEYVIYTEGSN----FKQVLKVPG---VDPTRTKT 268
G+ KT+++ K +++ TEG+ F V+ G +D ++T +
Sbjct: 1270 GIKKTLLKEGNTFRVDPETGGIKNESSWMVDTEGTALQRIFVGVVNNEGKNIIDFSKTSS 1329
Query: 269 NNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGV 328
N I E+ VLGIEAAR ++ E+ GL ++ RH ++ D M G + + R G+
Sbjct: 1330 NKIPEVVTVLGIEAARRKLLSELREAYLAYGLNINYRHYTILVDTMCQRGYLMAVSRTGI 1389
Query: 329 -VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTMKL 386
E + L R +FE TV+ L AA GE D + GV ++++G +GTG+ L + +
Sbjct: 1390 NRSETSGPLMRCSFEETVKVLMTAAAFGEKDPVRGVSASLVLGNQARIGTGLFDLLLDM 1448
>gb|AAB51210.1| (U73451) large subunit RNA polymerase II [Cruznema tripartitum]
Length = 633
Score = 161 bits (404), Expect = 1e-38
Identities = 115/371 (30%), Positives = 181/371 (47%), Gaps = 69/371 (18%)
Query: 37 YKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINV 96
YKL + + ++ EV +++ + +PGE VG +AAQS+GEP+TQMTLNTFHYAGV+ NV
Sbjct: 263 YKLNQEAFDWLLGEVETRFQQPIAQPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNV 322
Query: 97 TLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL-- 154
TLG+PR+ EI++ K TP +TV+L D +KA++V ++E TTL + T +
Sbjct: 323 TLGVPRLKEIINVSKMLKTPSLTVFLRGVAARDADKAKDVLCKLEHTTLRKVTANTAIYY 382
Query: 155 --DLINM------EFI--------------------VEIDPERLEKSGLTMEKVLKKLQS 186
D N E++ +E+D +R+ LTME++ ++
Sbjct: 383 DPDPKNTCIEEDEEWVSIFYEMPDFDPSRSSPWLLRLELDRKRMTDKKLTMEQIADRIHQ 442
Query: 187 SF----KSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHR-----------------L 225
F + L+ R + + D E+V K L
Sbjct: 443 GFGDDLNVIYTDDNADKLVFRLRITNQDGDKGGDEEQVDKMEDDMFLRCIESNMLSDLTL 502
Query: 226 KGLSGVGK-------------TIVRKEG-----DEYVIYTEGSNFKQVLKVPGVDPTRTK 267
+G++ + K I+ EG E+++ T+G+ +VL VD RT
Sbjct: 503 QGITSISKVYMHKPTTDDKKRVIITPEGGFKAIPEWILETDGTALLKVLSEQHVDSVRTT 562
Query: 268 TNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHG 327
+N+I EI E+LGIEA R +I E+ N + G V+ RH+ L+ D+MT G + I RHG
Sbjct: 563 SNDICEIFEILGIEAVRKSIEREMNNVISFDGSYVNYRHLALLCDVMTAKGHLLAITRHG 622
Query: 328 VVGEKASVLAR 338
+ ++ L R
Sbjct: 623 INRQEVGCLMR 633
>sp|P17545|RPB1_TRYBB DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT >gi|102111|pir||B31875
DNA-directed RNA polymerase (EC 2.7.7.6) 2 - Trypanosoma
brucei >gi|10503|emb|CAA31847.1| (X13492) RNA polymerase
II largest subunit [Trypanosoma brucei]
Length = 1766
Score = 155 bits (388), Expect = 8e-37
Identities = 113/422 (26%), Positives = 204/422 (47%), Gaps = 71/422 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y ++L PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 1054 KEYKLNDRAFEYLLKEIRTKYHQSLTTPGENIGAIAAQSCGEPATQMTLNTFHNAGISSK 1113
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ +N MTV L + ++ A++ IE TLE++ R
Sbjct: 1114 NVTLGVPRLLELLNVSRNQKHASMTVSLFPPYD-EKRNAQKAQHLIEYCTLESITRRIQF 1172
Query: 155 ---------------DLINMEFIV-----------------------EIDPERLEKSGLT 176
D++ +E+ V E+D + + L
Sbjct: 1173 IYDPDPRHTVVEADRDILELEWNVMDESDAELRIQEVVAGSPWVVRLELDVDMVTDKALD 1232
Query: 177 MEKVLKKLQSSFKSAEFE------MEGYTLIVRPKKFEKISDLRRLAEKV----KKHRLK 226
M+ V + + +S E + T+ +R + E + +L ++ + L+
Sbjct: 1233 MKDVKQAILRVDESYIIETGMANNVRQRTIRMRSRYNEGADSIPKLKREIPALLARVHLR 1292
Query: 227 GLSGVGKTIV-------------RKEGDE-YVIYTEGSNFKQV-LKVPG------VDPTR 265
G+ GV + ++ + G++ + I T+G+ ++ + V G ++ +
Sbjct: 1293 GIPGVRRALLKDTTEFTVDQATGKMSGNKIWAIDTDGTALRRAFIGVVGEDGKNIINAVK 1352
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N + E+ +LGIEAAR+ ++ E+ GL ++ RH ++ D + G + + R
Sbjct: 1353 TSSNKVPEVCSLLGIEAARSKMLTELREAYLAYGLNINYRHYTILVDTICQHGYLMAVSR 1412
Query: 326 HGV-VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
G+ + + L R +FE TV+ L AA GE D + GV N+++G VGTG+ L +
Sbjct: 1413 SGINRSDTSGPLMRCSFEETVKVLMAAASFGECDPVRGVSANLVLGNQARVGTGLFDLVL 1472
Query: 385 KL 386
+
Sbjct: 1473 NM 1474
>sp|P17546|RPB2_TRYBB DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT >gi|102110|pir||A31875
DNA-directed RNA polymerase (EC 2.7.7.6) 1 - Trypanosoma
brucei >gi|10505|emb|CAA31846.1| (X13491) RNA polymerase
II largest subunit [Trypanosoma brucei]
Length = 1766
Score = 155 bits (388), Expect = 8e-37
Identities = 113/422 (26%), Positives = 204/422 (47%), Gaps = 71/422 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y ++L PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 1054 KEYKLNDRAFEYLLKEIRTKYHQSLTTPGENIGAIAAQSCGEPATQMTLNTFHNAGISSK 1113
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ +N MTV L + ++ A++ IE TLE++ R
Sbjct: 1114 NVTLGVPRLLELLNVSRNQKHASMTVSLFPPYD-EKRNAQKAQHLIEYCTLESITRRIQF 1172
Query: 155 ---------------DLINMEFIV-----------------------EIDPERLEKSGLT 176
D++ +E+ V E+D + + L
Sbjct: 1173 IYDPDPRHTVVEADRDILELEWNVMDESDAELRIQEVVAGSPWVVRLELDVDMVTDKALD 1232
Query: 177 MEKVLKKLQSSFKSAEFE------MEGYTLIVRPKKFEKISDLRRLAEKV----KKHRLK 226
M+ V + + +S E + T+ +R + E + +L ++ + L+
Sbjct: 1233 MKDVKQAILRVDESYIIETGMANNVRQRTIRMRSRYNEGADSIPKLKREIPALLARVHLR 1292
Query: 227 GLSGVGKTIV-------------RKEGDE-YVIYTEGSNFKQV-LKVPG------VDPTR 265
G+ GV + ++ + G++ + I T+G+ ++ + V G ++ +
Sbjct: 1293 GIPGVRRALLKDTTEFTVDQATGKMSGNKIWAIDTDGTALRRAFIGVVGEDGKNIINAVK 1352
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N + E+ +LGIEAAR+ ++ E+ GL ++ RH ++ D + G + + R
Sbjct: 1353 TSSNKVPEVCSLLGIEAARSKMLTELREAYLAYGLNINYRHYTILVDTICQHGYLMAVSR 1412
Query: 326 HGV-VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
G+ + + L R +FE TV+ L AA GE D + GV N+++G VGTG+ L +
Sbjct: 1413 SGINRSDTSGPLMRCSFEETVKVLMAAASFGECDPVRGVSANLVLGNQARVGTGLFDLVL 1472
Query: 385 KL 386
+
Sbjct: 1473 NM 1474
>pir||B31494 DNA-directed RNA polymerase (EC 2.7.7.6) IIB - Trypanosoma brucei
Length = 1765
Score = 155 bits (388), Expect = 8e-37
Identities = 113/422 (26%), Positives = 204/422 (47%), Gaps = 71/422 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y ++L PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 1053 KEYKLNDRAFEYLLKEIRTKYHQSLTTPGENIGAIAAQSCGEPATQMTLNTFHNAGISSK 1112
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ +N MTV L + ++ A++ IE TLE++ R
Sbjct: 1113 NVTLGVPRLLELLNVSRNQKHASMTVSLFPPYD-EKRNAQKAQHLIEYCTLESITRRIQF 1171
Query: 155 ---------------DLINMEFIV-----------------------EIDPERLEKSGLT 176
D++ +E+ V E+D + + L
Sbjct: 1172 IYDPDPRHTVVEADRDILELEWNVMDESDAELRIQEVVAGSPWVVRLELDVDMVTDKALD 1231
Query: 177 MEKVLKKLQSSFKSAEFE------MEGYTLIVRPKKFEKISDLRRLAEKV----KKHRLK 226
M+ V + + +S E + T+ +R + E + +L ++ + L+
Sbjct: 1232 MKDVKQAILRVDESYIIETGMANNVRQRTIRMRSRYNEGADSIPKLKREIPALLARVHLR 1291
Query: 227 GLSGVGKTIV-------------RKEGDE-YVIYTEGSNFKQV-LKVPG------VDPTR 265
G+ GV + ++ + G++ + I T+G+ ++ + V G ++ +
Sbjct: 1292 GIPGVRRALLKDTTEFTVDQATGKMSGNKIWAIDTDGTALRRAFIGVVGEDGKNIINAVK 1351
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N + E+ +LGIEAAR+ ++ E+ GL ++ RH ++ D + G + + R
Sbjct: 1352 TSSNKVPEVCSLLGIEAARSKMLTELREAYLAYGLNINYRHYTILVDTICQHGYLMAVSR 1411
Query: 326 HGV-VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
G+ + + L R +FE TV+ L AA GE D + GV N+++G VGTG+ L +
Sbjct: 1412 SGINRSDTSGPLMRCSFEETVKVLMAAASFGECDPVRGVSANLVLGNQARVGTGLFDLVL 1471
Query: 385 KL 386
+
Sbjct: 1472 NM 1473
>gb|AAA30229.1| (J03157) RNA polymerase IIA largest subunit [Trypanosoma brucei]
Length = 1765
Score = 155 bits (388), Expect = 8e-37
Identities = 113/422 (26%), Positives = 204/422 (47%), Gaps = 71/422 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y ++L PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 1053 KEYKLNDRAFEYLLKEIRTKYHQSLTTPGENIGAIAAQSCGEPATQMTLNTFHNAGISSK 1112
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ +N MTV L + ++ A++ IE TLE++ R
Sbjct: 1113 NVTLGVPRLLELLNVSRNQKHASMTVSLFPPYD-EKRNAQKAQHLIEYCTLESITRRIQF 1171
Query: 155 ---------------DLINMEFIV-----------------------EIDPERLEKSGLT 176
D++ +E+ V E+D + + L
Sbjct: 1172 IYDPDPRHTVVEADRDILELEWNVMDESDAELRIQEVVAGSPWVVRLELDVDMVTDKALD 1231
Query: 177 MEKVLKKLQSSFKSAEFE------MEGYTLIVRPKKFEKISDLRRLAEKV----KKHRLK 226
M+ V + + +S E + T+ +R + E + +L ++ + L+
Sbjct: 1232 MKDVKQAILRVDESYIIETGMANNVRQRTIRMRSRYNEGADSIPKLKREIPALLARVHLR 1291
Query: 227 GLSGVGKTIV-------------RKEGDE-YVIYTEGSNFKQV-LKVPG------VDPTR 265
G+ GV + ++ + G++ + I T+G+ ++ + V G ++ +
Sbjct: 1292 GIPGVRRALLKDTTEFTVDQATGKMSGNKIWAIDTDGTALRRAFIGVVGEDGKNIINAVK 1351
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N + E+ +LGIEAAR+ ++ E+ GL ++ RH ++ D + G + + R
Sbjct: 1352 TSSNKVPEVCSLLGIEAARSKMLTELREAYLAYGLNINYRHYTILVDTICQHGYLMAVSR 1411
Query: 326 HGV-VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
G+ + + L R +FE TV+ L AA GE D + GV N+++G VGTG+ L +
Sbjct: 1412 SGINRSDTSGPLMRCSFEETVKVLMAAASFGECDPVRGVSANLVLGNQARVGTGLFDLVL 1471
Query: 385 KL 386
+
Sbjct: 1472 NM 1473
>gb|AAA30232.1| (J04841) RNA polymerase IIB largest subunit [Trypanosoma brucei]
Length = 1765
Score = 155 bits (388), Expect = 8e-37
Identities = 113/422 (26%), Positives = 204/422 (47%), Gaps = 71/422 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y ++L PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 1053 KEYKLNDRAFEYLLKEIRTKYHQSLTTPGENIGAIAAQSCGEPATQMTLNTFHNAGISSK 1112
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ +N MTV L + ++ A++ IE TLE++ R
Sbjct: 1113 NVTLGVPRLLELLNVSRNQKHASMTVSLFPPYD-EKRNAQKAQHLIEYCTLESITRRIQF 1171
Query: 155 ---------------DLINMEFIV-----------------------EIDPERLEKSGLT 176
D++ +E+ V E+D + + L
Sbjct: 1172 IYDPDPRHTVVEADRDILELEWNVMDESDAELRIQEVVAGSPWVVRLELDVDMVTDKALD 1231
Query: 177 MEKVLKKLQSSFKSAEFE------MEGYTLIVRPKKFEKISDLRRLAEKV----KKHRLK 226
M+ V + + +S E + T+ +R + E + +L ++ + L+
Sbjct: 1232 MKDVKQAILRVDESYIIETGMANNVRQRTIRMRSRYNEGADSIPKLKREIPALLARVHLR 1291
Query: 227 GLSGVGKTIV-------------RKEGDE-YVIYTEGSNFKQV-LKVPG------VDPTR 265
G+ GV + ++ + G++ + I T+G+ ++ + V G ++ +
Sbjct: 1292 GIPGVRRALLKDTTEFTVDQATGKMSGNKIWAIDTDGTALRRAFIGVVGEDGKNIINAVK 1351
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N + E+ +LGIEAAR+ ++ E+ GL ++ RH ++ D + G + + R
Sbjct: 1352 TSSNKVPEVCSLLGIEAARSKMLTELREAYLAYGLNINYRHYTILVDTICQHGYLMAVSR 1411
Query: 326 HGV-VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
G+ + + L R +FE TV+ L AA GE D + GV N+++G VGTG+ L +
Sbjct: 1412 SGINRSDTSGPLMRCSFEETVKVLMAAASFGECDPVRGVSANLVLGNQARVGTGLFDLVL 1471
Query: 385 KL 386
+
Sbjct: 1472 NM 1473
>pir||A31494 DNA-directed RNA polymerase (EC 2.7.7.6) IIA - Trypanosoma brucei
Length = 1765
Score = 155 bits (388), Expect = 8e-37
Identities = 113/422 (26%), Positives = 204/422 (47%), Gaps = 71/422 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y ++L PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 1053 KEYKLNDRAFEYLLKEIRTKYHQSLTTPGENIGAIAAQSCGEPATQMTLNTFHNAGISSK 1112
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ +N MTV L + ++ A++ IE TLE++ R
Sbjct: 1113 NVTLGVPRLLELLNVSRNQKHASMTVSLFPPYD-EKRNAQKAQHLIEYCTLESITRRIQF 1171
Query: 155 ---------------DLINMEFIV-----------------------EIDPERLEKSGLT 176
D++ +E+ V E+D + + L
Sbjct: 1172 IYDPDPRHTVVEADRDILELEWNVMDESDAELRIQEVVAGSPWVVRLELDVDMVTDKALD 1231
Query: 177 MEKVLKKLQSSFKSAEFE------MEGYTLIVRPKKFEKISDLRRLAEKV----KKHRLK 226
M+ V + + +S E + T+ +R + E + +L ++ + L+
Sbjct: 1232 MKDVKQAILRVDESYIIETGMANNVRQRTIRMRSRYNEGADSIPKLKREIPALLARVHLR 1291
Query: 227 GLSGVGKTIV-------------RKEGDE-YVIYTEGSNFKQV-LKVPG------VDPTR 265
G+ GV + ++ + G++ + I T+G+ ++ + V G ++ +
Sbjct: 1292 GIPGVRRALLKDTTEFTVDQATGKMSGNKIWAIDTDGTALRRAFIGVVGEDGKNIINAVK 1351
Query: 266 TKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGR 325
T +N + E+ +LGIEAAR+ ++ E+ GL ++ RH ++ D + G + + R
Sbjct: 1352 TSSNKVPEVCSLLGIEAARSKMLTELREAYLAYGLNINYRHYTILVDTICQHGYLMAVSR 1411
Query: 326 HGV-VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTM 384
G+ + + L R +FE TV+ L AA GE D + GV N+++G VGTG+ L +
Sbjct: 1412 SGINRSDTSGPLMRCSFEETVKVLMAAASFGECDPVRGVSANLVLGNQARVGTGLFDLVL 1471
Query: 385 KL 386
+
Sbjct: 1472 NM 1473
>pir||T31670 DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain -
Mastigamoeba invertens (fragment)
>gi|3511287|gb|AAC62246.1| (AF083338) DNA-dependent RNA
polymerase II largest subunit [Mastigamoeba invertens]
Length = 1690
Score = 143 bits (357), Expect = 3e-33
Identities = 121/425 (28%), Positives = 190/425 (44%), Gaps = 83/425 (19%)
Query: 47 IIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVA-------------- 92
II EV +++ RALV PGE VG +AAQS GEP+TQMTLNTFH AGV
Sbjct: 984 IIGEVREKFGRALVAPGEMVGAIAAQSFGEPTTQMTLNTFHSAGVGTKNVTLGVPRLKEL 1043
Query: 93 -EINVTLGLPRI-IEIVDARKNPSTPMMTVYLDEEHRYDREKAEE---------VARRIE 141
+N+ L P I I + D N V L +H R+ V ++
Sbjct: 1044 INVNMALRTPNISIFVQDPFCNSEENATKVPLHIKHTTVRDLVSRAEIIYDPMYVVDQMT 1103
Query: 142 GTTLENLARTTT-------------LDLINME------FIVEI--DPERLEKSGLTMEKV 180
G + RT D +N + F++ + D + +++ L E V
Sbjct: 1104 GEAYFDCTRTVVPEDEFFVQDNYMQADRLNYQTHSYSSFVLRVMLDTKVMQQMELKEESV 1163
Query: 181 LKKLQSSFKSAEFEMEGYTLIVRPKKFEKI------------------SDLRRLAEKVKK 222
+ +++ F+ A + + +P+ ++ LR + E +
Sbjct: 1164 VSIVKAEFEDAVEIISTVNDLNKPRMRIRLVRERAEAEAAVDEDRGEDDRLRDMEEIIMG 1223
Query: 223 HRLKGLSGVGKTIVRKEGDEYVIYTEGS-------------------NFKQVLKVPGVDP 263
+ G+ G+ K +V E + G+ V+ P VDP
Sbjct: 1224 LHVHGIRGMTKVMVDDSRTEKWVDERGALQTRRFWPLDGEVKKDTAPPLLDVMVHPAVDP 1283
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
RT TN+I I +VLG+EAAR A+++E+ + + G ++IRH++++ D+MT G + I
Sbjct: 1284 YRTTTNSITVINDVLGVEAARAALLKELRDVLGFDGSYINIRHLLMLVDVMTFRGYLMSI 1343
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
R G+ +L RA+FE TV L +AA+ D L GV +N+++GQ PVGTG L
Sbjct: 1344 TRFGMNRTDNGILMRASFEETVDVLQDAAQFAGHDELRGVSDNIMLGQVAPVGTGTFDLL 1403
Query: 384 MKLPL 388
+ L
Sbjct: 1404 LDAAL 1408
>gb|AAF26622.1|AF138972_1 (AF138972) RNA polymerase II largest subunit [Semibalanus
balanoides]
Length = 256
Score = 126 bits (314), Expect = 4e-28
Identities = 70/184 (38%), Positives = 104/184 (56%), Gaps = 30/184 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+Y+L+ E +I E+ + +A+V PGE VG +AAQS+GEP+TQMTLNTFH+AGV+
Sbjct: 64 EEYRLSSEAFEWLIGEIDTRFHQAMVNPGEMVGALAAQSLGEPATQMTLNTFHFAGVSSK 123
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT-- 152
NVTLG+PR+ EI++ K P P +TV+L D EKA+ V R+E TTL + T
Sbjct: 124 NVTLGVPRLKEIINISKKPKAPSLTVFLTGASARDAEKAKSVLCRLEHTTLRKVTANTAI 183
Query: 153 --------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKKL 184
T+ + EF+ +E+D +R+ LTME++ +K+
Sbjct: 184 YYDPDPQNTVIAEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQISEKI 243
Query: 185 QSSF 188
+ F
Sbjct: 244 NAGF 247
>gb|AAF26664.1|AF139014_1 (AF139014) RNA polymerase II largest subunit [Tanystylum
orbiculare]
Length = 256
Score = 125 bits (312), Expect = 6e-28
Identities = 70/187 (37%), Positives = 107/187 (56%), Gaps = 30/187 (16%)
Query: 32 KYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGV 91
K E+++L+ + ++ E+ +++A V PGE VG +AAQS+GEP+TQMTLNTFHYAGV
Sbjct: 61 KVAEEFRLSTEAFDWLLGEIDTRFQQAQVMPGEMVGALAAQSLGEPATQMTLNTFHYAGV 120
Query: 92 AEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLART 151
+ NVTLG+PR+ EI++ K P TP +TV+L D EKA++V R+E TTL +
Sbjct: 121 SAKNVTLGVPRLKEIINVSKKPKTPSLTVFLTGAAARDAEKAKDVLCRLEHTTLRKVTAN 180
Query: 152 T----------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVL 181
T T+ + EF+ +E+D +R+ LTME++
Sbjct: 181 TAIYYDPDPQNTVISDDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIA 240
Query: 182 KKLQSSF 188
+K+ + F
Sbjct: 241 EKINAGF 247
>gb|AAF26620.1|AF138970_1 (AF138970) RNA polymerase II largest subunit [Armadillidium
vulgare]
Length = 433
Score = 123 bits (305), Expect = 4e-27
Identities = 67/187 (35%), Positives = 104/187 (54%), Gaps = 30/187 (16%)
Query: 32 KYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGV 91
K +E+Y+LT ++ E+ + +A+ PGE VG +AAQS+GEP+TQMTLNTFH+AGV
Sbjct: 210 KVSEEYRLTTEAFNWLMGEIETRFNQAIANPGEMVGALAAQSLGEPATQMTLNTFHFAGV 269
Query: 92 AEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLART 151
+ NVTLG+PR+ EI++ K P P +TV+L D EKA+ V R+E TTL +
Sbjct: 270 SSKNVTLGVPRLKEIINISKKPKAPSLTVFLLGAAARDAEKAKNVLCRLEHTTLRKVTSN 329
Query: 152 TTL---------------DLINMEF---------------IVEIDPERLEKSGLTMEKVL 181
T + + +N+ + +E+D +++ LTME++
Sbjct: 330 TAIYYDPDPQNTVIEEDQEFVNVYYEMPDFDVSRISPWLLRIELDRKKMTDKKLTMEQIS 389
Query: 182 KKLQSSF 188
+K+ S F
Sbjct: 390 QKINSGF 396
>gb|AAF26638.1|AF138988_1 (AF138988) RNA polymerase II largest subunit [Metajapyx
subterraneus]
Length = 256
Score = 123 bits (305), Expect = 4e-27
Identities = 69/183 (37%), Positives = 103/183 (55%), Gaps = 30/183 (16%)
Query: 36 KYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEIN 95
+++L+ E +I EV +++A V PGE VG +AAQS+GEP+TQMTLNTFH+AGV+ N
Sbjct: 65 EFRLSSEAFEWLIGEVETRFQQAQVXPGEMVGALAAQSLGEPATQMTLNTFHFAGVSSKN 124
Query: 96 VTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT--- 152
VTLG+PR+ EI++ K P P +TV+L D EKA+ V R+E TTL + T
Sbjct: 125 VTLGVPRLKEIINISKKPKAPSLTVFLTGAAAXDAEKAKNVLCRLEHTTLRKVTANTAIY 184
Query: 153 -------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKKLQ 185
T+ + EF+ +E+D +R+ LTME++ +K+
Sbjct: 185 YDPDPQNTVIAEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEKIN 244
Query: 186 SSF 188
+ F
Sbjct: 245 AGF 247
>sp|P14248|RPB1_PLAFD DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT >gi|66976|pir||RNZQ2L
DNA-directed RNA polymerase (EC 2.7.7.6) II large chain -
malaria parasite (Plasmodium falciparum)
>gi|9943|emb|CAA34560.1| (X16561) RNA polymerase II large
subunit (AA 1-2452) [Plasmodium falciparum]
Length = 2452
Score = 116 bits (287), Expect = 5e-25
Identities = 57/131 (43%), Positives = 90/131 (68%), Gaps = 2/131 (1%)
Query: 18 LPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEP 77
L ++ L KL+ + +K++ ++ ++ E+ K + ++L PGE VG +AAQSIGEP
Sbjct: 1359 LKAHLRTYLNSKLL--TQTHKVSVKGLDWLLQEIEKIFYKSLCHPGECVGALAAQSIGEP 1416
Query: 78 STQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVA 137
+TQMTLNTFH+AGV NVTLG+PR+ E+++ KN TP T+YLD+ D++KA+++
Sbjct: 1417 ATQMTLNTFHFAGVGSKNVTLGVPRLKELINIVKNVKTPSTTIYLDDMVSNDQQKAKDIL 1476
Query: 138 RRIEGTTLENL 148
++E TTL+ L
Sbjct: 1477 TKLEYTTLKQL 1487
Score = 110 bits (273), Expect = 2e-23
Identities = 70/214 (32%), Positives = 115/214 (53%), Gaps = 19/214 (8%)
Query: 184 LQSSFKSAE--FEMEGYTLIVRPKKFEKISD--LRRLAEK-VKKHRLKGLSGVGKTIVRK 238
+++S K+AE E++ I E D L++L E+ + +L+G+ + K +R+
Sbjct: 1836 MKTSTKNAEEDLELKNKNHIEHNISREDTEDTFLKKLMEQCLSTLKLRGIENITKVYMRE 1895
Query: 239 EG--------------DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAAR 284
E +V+ T+G N + + P VD +T +N+I EI EVLGIEA R
Sbjct: 1896 ESKITYDSDNGKFVRSSHWVLDTDGCNLENIFCAPQVDFKKTVSNDIVEIFEVLGIEAVR 1955
Query: 285 NAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEIT 344
A+++E+ + V+ RH+ ++ D+MT G + I RHG+ L + +FE T
Sbjct: 1956 RALLKELRTVISFDSSYVNYRHLSILCDVMTQKGYLMSITRHGINRVDKGPLIKCSFEET 2015
Query: 345 VQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
V+ L EAA +VDNL G+ EN+++GQ +GTG
Sbjct: 2016 VEILLEAAAFAQVDNLRGITENIMLGQLCKIGTG 2049
>pir||T18492 hypothetical protein C0805w - malaria parasite (Plasmodium
falciparum) >gi|3758846|emb|CAB11131.1| (Z98551)
DNA-directed RNA polymerase II [Plasmodium falciparum]
Length = 2457
Score = 116 bits (287), Expect = 5e-25
Identities = 57/131 (43%), Positives = 90/131 (68%), Gaps = 2/131 (1%)
Query: 18 LPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEP 77
L ++ L KL+ + +K++ ++ ++ E+ K + ++L PGE VG +AAQSIGEP
Sbjct: 1356 LKAHLRTYLNSKLL--TQTHKVSVKGLDWLLQEIEKIFYKSLCHPGECVGALAAQSIGEP 1413
Query: 78 STQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVA 137
+TQMTLNTFH+AGV NVTLG+PR+ E+++ KN TP T+YLD+ D++KA+++
Sbjct: 1414 ATQMTLNTFHFAGVGSKNVTLGVPRLKELINIVKNVKTPSTTIYLDDMVSNDQQKAKDIL 1473
Query: 138 RRIEGTTLENL 148
++E TTL+ L
Sbjct: 1474 TKLEYTTLKQL 1484
Score = 110 bits (273), Expect = 2e-23
Identities = 70/214 (32%), Positives = 115/214 (53%), Gaps = 19/214 (8%)
Query: 184 LQSSFKSAE--FEMEGYTLIVRPKKFEKISD--LRRLAEK-VKKHRLKGLSGVGKTIVRK 238
+++S K+AE E++ I E D L++L E+ + +L+G+ + K +R+
Sbjct: 1834 MKTSTKNAEEDLELKNKNHIEHNISREDTEDTFLKKLMEQCLSTLKLRGIENITKVYMRE 1893
Query: 239 EG--------------DEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAAR 284
E +V+ T+G N + + P VD +T +N+I EI EVLGIEA R
Sbjct: 1894 ESKITYDSDNGKFVRSSHWVLDTDGCNLENIFCAPQVDFKKTVSNDIVEIFEVLGIEAVR 1953
Query: 285 NAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEIT 344
A+++E+ + V+ RH+ ++ D+MT G + I RHG+ L + +FE T
Sbjct: 1954 RALLKELRTVISFDSSYVNYRHLSILCDVMTQKGYLMSITRHGINRVDKGPLIKCSFEET 2013
Query: 345 VQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
V+ L EAA +VDNL G+ EN+++GQ +GTG
Sbjct: 2014 VEILLEAAAFAQVDNLRGITENIMLGQLCKIGTG 2047
>gb|AAC99803.1| (U24217) RNA polymerase II largest subunit [Kluyveromyces lactis]
Length = 414
Score = 113 bits (279), Expect = 5e-24
Identities = 62/153 (40%), Positives = 89/153 (57%), Gaps = 2/153 (1%)
Query: 247 TEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRH 306
T+G N +V+ V GVD +R TN+ +I VLGIEA R A+ E+ N + G V+ RH
Sbjct: 3 TDGVNLSEVMTVSGVDGSRIYTNSFIDIMNVLGIEAGRAALYREVYNVIASDGSYVNYRH 62
Query: 307 IMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIEN 366
+ L+ D+MT G + + RHG L R +FE TV+ LFEA E+D+ GV EN
Sbjct: 63 MALLVDVMTSQGFLMSVTRHGFNRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSEN 122
Query: 367 VLIGQPVPVGTGM--VKLTMKLPLRPQKEKEEV 397
V++GQ P+GTG V + + ++ Q E +EV
Sbjct: 123 VILGQIAPIGTGAFDVMIDDESLVKYQPEHKEV 155
>gb|AAC47783.1| (AF009154) RNA polymerase II large subunit [Leishmania amazonensis]
Length = 422
Score = 110 bits (273), Expect = 2e-23
Identities = 56/123 (45%), Positives = 85/123 (68%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN +TV L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVTVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47793.1| (AF009164) RNA polymerase II large subunit [Leishmania mexicana]
Length = 422
Score = 110 bits (273), Expect = 2e-23
Identities = 56/123 (45%), Positives = 85/123 (68%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN +TV L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVTVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47789.1| (AF009160) RNA polymerase II large subunit [Leishmania herreri]
Length = 422
Score = 110 bits (272), Expect = 3e-23
Identities = 55/123 (44%), Positives = 86/123 (69%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++Y+L E ++ E+ +Y+++L+ PGE +GT+AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYRLNDKAFEYLLKEIRTKYQQSLITPGEIIGTIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN ++V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVSVCLIREYQ-KRNKAQEAQQFIEHCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>pir||T07796 DNA-directed RNA polymerase (EC 2.7.7.6) largest chain - soybean
(fragment) >gi|18732|emb|CAA36733.1| (X52492)
DNA-directed RNA polymerase [Glycine max]
Length = 625
Score = 109 bits (270), Expect = 5e-23
Identities = 60/167 (35%), Positives = 92/167 (54%), Gaps = 13/167 (7%)
Query: 225 LKGLSGVGKTIVR-------------KEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNNI 271
L+G+ + K ++ K +E+++ TEG N V+ VD TRT +N++
Sbjct: 120 LRGIPDINKVFIKNTKVQKFDVNQGFKPNEEWMLDTEGVNLLAVMCHEDVDVTRTTSNHL 179
Query: 272 HEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGE 331
E+ EVLGIEA R A+++E+ + G V+ RH+ ++ D MT G + I RHG+
Sbjct: 180 IEVIEVLGIEAVRRALLDELRVVISFDGSYVNYRHLAILCDTMTYRGHLMAITRHGINRN 239
Query: 332 KASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
+ R +FE TV L +AA E D L GV EN+++GQ P+GTG
Sbjct: 240 DTGPMMRCSFEETVDILLDAAVYAETDYLRGVTENIMLGQLAPIGTG 286
>pir||S14181 DNA-directed RNA polymerase (EC 2.7.7.6) largest chain (isoform
B1) - soybean (fragment)
Length = 650
Score = 109 bits (270), Expect = 5e-23
Identities = 60/167 (35%), Positives = 92/167 (54%), Gaps = 13/167 (7%)
Query: 225 LKGLSGVGKTIVR-------------KEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNNI 271
L+G+ + K ++ K +E+++ TEG N V+ VD TRT +N++
Sbjct: 116 LRGIPDINKVFIKNTKVQKFDVNQGFKPNEEWMLDTEGVNLLAVMCHEDVDVTRTTSNHL 175
Query: 272 HEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGE 331
E+ EVLGIEA R A+++E+ + G V+ RH+ ++ D MT G + I RHG+
Sbjct: 176 IEVIEVLGIEAVRRALLDELRVVISFDGSYVNYRHLAILCDTMTYRGHLMAITRHGINRN 235
Query: 332 KASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
+ R +FE TV L +AA E D L GV EN+++GQ P+GTG
Sbjct: 236 DTGPMMRCSFEETVDILLDAAVYAETDYLRGVTENIMLGQLAPIGTG 282
>sp|P27625|RPC1_PLAFA DNA-DIRECTED RNA POLYMERASE III LARGEST SUBUNIT
>gi|160596|gb|AAA29729.1| (M73770) RNA polymerase III
largest subunit [Plasmodium falciparum]
Length = 2339
Score = 109 bits (269), Expect = 7e-23
Identities = 56/146 (38%), Positives = 89/146 (60%)
Query: 237 RKEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMR 296
+K+ Y I EG++ VL + GVD +N++ + +VLGIEAAR II EI +
Sbjct: 2167 KKKKTVYSILVEGNSLNYVLGLEGVDFKHIISNHVINVFQVLGIEAARITIINEIKKCVE 2226
Query: 297 EQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGE 356
+++DIRHIML+ADIM G + I R G+ + S L A+FE T +HLF ++
Sbjct: 2227 AYSIDIDIRHIMLLADIMAFTGDILGINRFGIQKARQSTLMLASFEETNEHLFVSSFFKN 2286
Query: 357 VDNLSGVIENVLIGQPVPVGTGMVKL 382
VD ++ + E++++G+ +P+GTG +L
Sbjct: 2287 VDEINNISESIIVGKNIPIGTGAFQL 2312
Score = 90.9 bits (222), Expect = 2e-17
Identities = 44/97 (45%), Positives = 69/97 (70%), Gaps = 2/97 (2%)
Query: 52 VKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARK 111
+ +Y + + PG+AVG+++AQSIGEP TQMTL TFH+AGVA +NVTLG+PRI EI++A
Sbjct: 1769 IYKYFKYISTPGDAVGSISAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASN 1828
Query: 112 NPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENL 148
+ TP++ + L+ Y+ A + ++E TT+ ++
Sbjct: 1829 SIQTPILNIPLEVNDNYN--FALMMKSKLEKTTIRDI 1863
>pir||A45597 DNA-directed RNA polymerase (EC 2.7.7.6) III largest chain - malaria
parasite (Plasmodium falciparum)
Length = 2339
Score = 109 bits (269), Expect = 7e-23
Identities = 56/146 (38%), Positives = 89/146 (60%)
Query: 237 RKEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMR 296
+K+ Y I EG++ VL + GVD +N++ + +VLGIEAAR II EI +
Sbjct: 2167 KKKKTVYSILVEGNSLNYVLGLEGVDFKHIISNHVINVFQVLGIEAARITIINEIKKCVE 2226
Query: 297 EQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGE 356
+++DIRHIML+ADIM G + I R G+ + S L A+FE T +HLF ++
Sbjct: 2227 AYSIDIDIRHIMLLADIMAFTGDILGINRFGIQKARQSTLMLASFEETNEHLFVSSFFKN 2286
Query: 357 VDNLSGVIENVLIGQPVPVGTGMVKL 382
VD ++ + E++++G+ +P+GTG +L
Sbjct: 2287 VDEINNISESIIVGKNIPIGTGAFQL 2312
Score = 90.9 bits (222), Expect = 2e-17
Identities = 44/97 (45%), Positives = 69/97 (70%), Gaps = 2/97 (2%)
Query: 52 VKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARK 111
+ +Y + + PG+AVG+++AQSIGEP TQMTL TFH+AGVA +NVTLG+PRI EI++A
Sbjct: 1769 IYKYFKYISTPGDAVGSISAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASN 1828
Query: 112 NPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENL 148
+ TP++ + L+ Y+ A + ++E TT+ ++
Sbjct: 1829 SIQTPILNIPLEVNDNYN--FALMMKSKLEKTTIRDI 1863
>gb|AAC47782.1| (AF009153) RNA polymerase II large subunit [Leishmania adleri]
>gi|2581922|gb|AAC47788.1| (AF009159) RNA polymerase II
large subunit [Leishmania gymnodactyli]
>gi|2581928|gb|AAC47791.1| (AF009162) RNA polymerase II
large subunit [Leishmania hoogstraali]
Length = 422
Score = 109 bits (269), Expect = 7e-23
Identities = 55/123 (44%), Positives = 84/123 (67%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEVIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47795.1| (AF009166) RNA polymerase II large subunit [Leishmania tarentolae]
Length = 422
Score = 109 bits (269), Expect = 7e-23
Identities = 55/123 (44%), Positives = 84/123 (67%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEVIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47784.1| (AF009155) RNA polymerase II large subunit [Leishmania
braziliensis]
Length = 422
Score = 108 bits (268), Expect = 9e-23
Identities = 55/123 (44%), Positives = 84/123 (67%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47785.1| (AF009156) RNA polymerase II large subunit [Leishmania deanei]
Length = 422
Score = 108 bits (268), Expect = 9e-23
Identities = 55/123 (44%), Positives = 84/123 (67%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47786.1| (AF009157) RNA polymerase II large subunit [Leishmania donovani]
Length = 422
Score = 108 bits (268), Expect = 9e-23
Identities = 55/123 (44%), Positives = 84/123 (67%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47790.1| (AF009161) RNA polymerase II large subunit [Leishmania hertigi]
Length = 422
Score = 108 bits (268), Expect = 9e-23
Identities = 55/123 (44%), Positives = 84/123 (67%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47794.1| (AF009165) RNA polymerase II large subunit [Leishmania panamensis]
Length = 422
Score = 108 bits (268), Expect = 9e-23
Identities = 55/123 (44%), Positives = 84/123 (67%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47796.1| (AF009167) RNA polymerase II large subunit [Leishmania tropica]
Length = 422
Score = 108 bits (268), Expect = 9e-23
Identities = 55/123 (44%), Positives = 84/123 (67%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVAVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLI 157
+I
Sbjct: 338 QII 340
>gb|AAC47787.1| (AF009158) RNA polymerase II large subunit [Endotrypanum
monterogei]
Length = 422
Score = 108 bits (267), Expect = 1e-22
Identities = 61/162 (37%), Positives = 98/162 (59%), Gaps = 10/162 (6%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++Y+L E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 221 KEYRLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 280
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN ++V L E++ R KA+E + IE TL N+ TTT+
Sbjct: 281 NVTLGVPRLLELLNVSKNQRNASVSVCLIREYQ-KRNKAQEAQQFIEYCTLANI--TTTV 337
Query: 155 DLINMEFIVEIDPERLEKSGLTMEKVLKKLQSSFKSAEFEME 196
+I DP+ E++L+ Q+ E E +
Sbjct: 338 QII-------YDPDTRHTVVAEDEEMLRWEQAVMNEEEDEQD 372
>gb|AAA92868.1| (L34213) DNA-dependent RNA polymerase largest subunit [lymphocystis
disease virus]
Length = 1199
Score = 107 bits (265), Expect = 2e-22
Identities = 98/377 (25%), Positives = 173/377 (44%), Gaps = 17/377 (4%)
Query: 16 KDLPESVKQELYEKLIKYNEK---YKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQ 72
K LPE + QE + + N K + K+ + + V K Y A+++PGEAVG + AQ
Sbjct: 817 KQLPEPI-QEYVLQFHRNNIKAGAVLIPKSACQIWTETVRKAYVAAIIDPGEAVGIICAQ 875
Query: 73 SIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREK 132
+IG TQ TLNTFH AG G + EI+ + P + L E
Sbjct: 876 AIGAKQTQQTLNTFHKAGTLS---EAGHRQFGEILSLTQKPKKRSCYLKLKNVPSNPTEI 932
Query: 133 AEEVARRIEGTTLENLARTTTLDLINME----FIVEIDPERLEKSGLTMEKVLKKLQSSF 188
+ + + L + + + ++ ++++ + K ++ + ++ F
Sbjct: 933 RDLLGCSLICKPLTDCSEPGAFKVTYLKTKTILEIKLNIDVCFKHRISPDDIISAAVQKF 992
Query: 189 KSAEFEMEGY--TLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGK-TIVRKEGDEYVI 245
++ F + ++++ I + + K+K ++G++G I + EY I
Sbjct: 993 EAPYFCLASTFDSILLSWSTHCCIDKIFKDVLKLKIGPVQGVTGYDLYPIPHTKPIEYAI 1052
Query: 246 YTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIR 305
T+GSN +++L P + +++ +I + LG+ A R + E I + E E+
Sbjct: 1053 VTKGSNLQKLLSHPHIKTEGAICDDVWDIYKTLGLAAVRKRLREMIKTCVGE---EIYPE 1109
Query: 306 HIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIE 365
HI L+ D MT G PI R+ + + L+RAAFE ++ L +A GE D L+GV
Sbjct: 1110 HIQLLVDQMTYKGKPMPIDRYTMRTHQVGPLSRAAFEESLDILVNSAVIGETDTLNGVSA 1169
Query: 366 NVLIGQPVPVGTGMVKL 382
V+ G+ +GTG KL
Sbjct: 1170 CVIAGKKTFIGTGFPKL 1186
>gb|AAF67243.1| (AF151727) RNA polymerase II large subunit [Leishmania enriettii]
Length = 429
Score = 107 bits (265), Expect = 2e-22
Identities = 54/123 (43%), Positives = 84/123 (67%), Gaps = 3/123 (2%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
++YKL E ++ E+ +Y+++L+ PGE +G +AAQS GEP+TQMTLNTFH AG++
Sbjct: 224 KEYKLNDKAFEYLLKEIRTKYQQSLITPGEIIGAIAAQSCGEPATQMTLNTFHNAGISSK 283
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVTLG+PR++E+++ KN + V L +++ R KA+E + IE TL N+ TTT+
Sbjct: 284 NVTLGVPRLLELLNVSKNQRNASVAVCLIHDYQ-KRNKAQEAQQFIEYCTLANI--TTTV 340
Query: 155 DLI 157
+I
Sbjct: 341 QII 343
>sp|P91875|RPA1_DROME DNA-DIRECTED RNA POLYMERASE I LARGEST SUBUNIT >gi|7511845|pir||T13803
DNA-directed RNA polymerase (EC 2.7.7.6) I large chain -
fruit fly (Drosophila melanogaster)
>gi|1865779|emb|CAA70321.1| (Y09103) largest subunit of
RNA polymerase I (A) [Drosophila melanogaster]
Length = 1644
Score = 104 bits (258), Expect = 1e-21
Identities = 65/188 (34%), Positives = 103/188 (54%), Gaps = 4/188 (2%)
Query: 200 LIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIYTEGSNFKQVLKVP 259
L VR +K + S +R LA K H+++ + I + D+ ++ T+G N ++ +
Sbjct: 1459 LSVRYQKPDLTSIIRELAGKSVVHQVQHIKRA--IIYKGNDDDQLLKTDGINIGEMFQHN 1516
Query: 260 GV-DPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDG 318
+ D R +N+IH IA GIEAA I++E+ N + G+ VD RH+ L+AD MT DG
Sbjct: 1517 KILDLNRLYSNDIHAIARTYGIEAASQVIVKEVSNVFKVYGITVDRRHLSLIADYMTFDG 1576
Query: 319 VVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
+P+ R G + +S L + +FE ++Q L AA G D LS +++G PV GTG
Sbjct: 1577 TFQPLSRKG-MEHSSSPLQQMSFESSLQFLKSAAGFGRADELSSPSSRLMVGLPVRNGTG 1635
Query: 379 MVKLTMKL 386
+L K+
Sbjct: 1636 AFELLTKI 1643
Score = 98.7 bits (242), Expect = 1e-19
Identities = 69/173 (39%), Positives = 98/173 (55%), Gaps = 19/173 (10%)
Query: 8 KSLIEKKGKDLPESV----KQELY-----EKLIKYNEKYKLTKAEV-ETIIDEVVKEYER 57
K+L KK P+ KQ+LY E+ K Y K + ETI D + + +
Sbjct: 1111 KALYRKKYARCPDPTVAVYKQDLYYGSVSERTRKLITDYAKRKPALKETIADIMRVKTIK 1170
Query: 58 ALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVD-ARKNPSTP 116
+L PGE VG +AAQSIGEPSTQMTLNTFH+AG E+NVTLG+PR+ EI+ A N TP
Sbjct: 1171 SLAAPGEPVGLIAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMLASSNIKTP 1230
Query: 117 MMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPER 169
M + + ++ +AE++ + TL NL L+ +++ + +DPER
Sbjct: 1231 SMDIPIKPGQQH---QAEKLRINLNSVTLANL-----LEYVHVSTGLTLDPER 1275
>gb|AAF58234.1| (AE003814) RpI1 gene product [Drosophila melanogaster]
Length = 1642
Score = 104 bits (257), Expect = 2e-21
Identities = 65/188 (34%), Positives = 103/188 (54%), Gaps = 4/188 (2%)
Query: 200 LIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTIVRKEGDEYVIYTEGSNFKQVLKVP 259
L VR +K + S +R LA K H+++ + I + D+ ++ T+G N ++ +
Sbjct: 1457 LSVRYQKPDLTSIIRELAGKSVVHQVQHIKRA--IIYKGTDDDQLLKTDGINIGEMFQHN 1514
Query: 260 GV-DPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDG 318
+ D R +N+IH IA GIEAA I++E+ N + G+ VD RH+ L+AD MT DG
Sbjct: 1515 KILDLNRLYSNDIHAIARTYGIEAASQVIVKEVSNVFKVYGITVDRRHLSLIADYMTFDG 1574
Query: 319 VVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
+P+ R G + +S L + +FE ++Q L AA G D LS +++G PV GTG
Sbjct: 1575 TFQPLSRKG-MEHSSSPLQQMSFESSLQFLKSAAGFGRADELSSPSSRLMVGLPVRNGTG 1633
Query: 379 MVKLTMKL 386
+L K+
Sbjct: 1634 AFELLTKI 1641
Score = 98.7 bits (242), Expect = 1e-19
Identities = 69/173 (39%), Positives = 98/173 (55%), Gaps = 19/173 (10%)
Query: 8 KSLIEKKGKDLPESV----KQELY-----EKLIKYNEKYKLTKAEV-ETIIDEVVKEYER 57
K+L KK P+ KQ+LY E+ K Y K + ETI D + + +
Sbjct: 1110 KALYRKKYARCPDPTVAVYKQDLYYGSVSERTRKLITDYAKRKPALKETIADIMRVKTIK 1169
Query: 58 ALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVD-ARKNPSTP 116
+L PGE VG +AAQSIGEPSTQMTLNTFH+AG E+NVTLG+PR+ EI+ A N TP
Sbjct: 1170 SLAAPGEPVGLIAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMLASSNIKTP 1229
Query: 117 MMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPER 169
M + + ++ +AE++ + TL NL L+ +++ + +DPER
Sbjct: 1230 SMDIPIKPGQQH---QAEKLRINLNSVTLANL-----LEYVHVSTGLTLDPER 1274
>gi|9628206 RNA polymerase subunit 1 [African swine fever virus]
>gi|1173142|sp|P42486|RPO1_ASFB7 DNA-DIRECTED RNA
POLYMERASE SUBUNIT 1 >gi|7460262|pir||S78060 probable
DNA-directed RNA polymerase (EC 2.7.7.6) II - African
swine fever virus >gi|311526|emb|CAA79697.1| (Z21489) RNA
polymerase largest subunit [African swine fever virus]
>gi|780468|gb|AAA65328.1| (U18466) RNA polymerase subunit
1 [African swine fever virus] >gi|1097490|prf||2113434DE
RNA polymerase:SUBUNIT=1 [African swine fever virus]
Length = 1450
Score = 103 bits (254), Expect = 4e-21
Identities = 107/414 (25%), Positives = 184/414 (43%), Gaps = 78/414 (18%)
Query: 39 LTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTL 98
+T ++ I+D + +Y ++L+ GEAVG +AAQS+ EP TQ L++ H + N +
Sbjct: 1014 ITCEQMSAILDLIRLQYTQSLINYGEAVGILAAQSVSEPLTQYMLDSHHRSVAGGTNKS- 1072
Query: 99 GLPRIIEIVDARK---NPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLA------ 149
G+ R EI A+ S+ M+ + E ++ A+E+A IE T E L
Sbjct: 1073 GIVRPQEIFSAKPVEAEQSSEMLLRLKNPEVETNKTYAQEIANSIELITFERLILQWHLL 1132
Query: 150 ----RTTTLDLINMEFIVEID--------------PE-------RLEKSGLTM------- 177
+T +++ +F +++ PE RLE + TM
Sbjct: 1133 YETYSSTKKNVMYPDFASDVEWMTDFLENHPLLQPPEDIANWCIRLELNKTTMILKSISL 1192
Query: 178 EKVLKKLQSS------FKSAEFEMEGYTLIVR----PKKFEKISDLR---------RLAE 218
E ++ L++ S E G +I+R F + ++ R + +
Sbjct: 1193 ESIINSLRAKHPNTYIMHSVENTASGIPIIIRIYLRESAFRRSTNTRMATDEKIAVNVVD 1252
Query: 219 KVKKHRLKGLSGVGKTIVRK--------EG------DEYVIYTEGSNFKQVLKVPGVDPT 264
K+ ++G+ G+ V K +G + Y I T G+N + +DP
Sbjct: 1253 KLLNSTIRGIPGIKNANVVKLMRHRVDAQGKLVRLDNIYAIKTNGTNIFGAMLDDNIDPY 1312
Query: 265 RTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIG 324
+++I + E+ GIEAAR II EI M ++G + RH+++ AD+MT G V +
Sbjct: 1313 TIVSSSIGDTMELYGIEAARQKIISEIRTVMGDKG--PNHRHLLMYADLMTRTGQVTSLE 1370
Query: 325 RHGV-VGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGT 377
+ G+ E ++VL R A VQ L +AA V+ + G+ L+G +GT
Sbjct: 1371 KAGLNAREPSNVLLRMALSSPVQVLTDAAVDSAVNPIYGIAAPTLMGSVPRIGT 1424
>emb|CAA36734.1| (X52493) DNA-directed RNA polymerase [Glycine max]
Length = 494
Score = 98.7 bits (242), Expect = 1e-19
Identities = 50/118 (42%), Positives = 72/118 (60%)
Query: 261 VDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVV 320
VD TRT +N++ E+ EVLGIEA R A+++E+ + G V+ RH+ ++ D MT G +
Sbjct: 9 VDATRTTSNHLIEVIEVLGIEAVRRALLDELRVVISFDGSYVNYRHLAILCDTMTYRGHL 68
Query: 321 RPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
I RHG+ + R +FE TV L +AA E D L GV EN+++GQ P+GTG
Sbjct: 69 MAITRHGINRNDTGPMMRCSFEETVDILLDAAVYAETDYLRGVTENIMLGQLAPIGTG 126
>pir||S14182 DNA-directed RNA polymerase (EC 2.7.7.6) largest chain (isoform
B2) - soybean (fragment)
Length = 491
Score = 98.7 bits (242), Expect = 1e-19
Identities = 50/118 (42%), Positives = 72/118 (60%)
Query: 261 VDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVV 320
VD TRT +N++ E+ EVLGIEA R A+++E+ + G V+ RH+ ++ D MT G +
Sbjct: 6 VDATRTTSNHLIEVIEVLGIEAVRRALLDELRVVISFDGSYVNYRHLAILCDTMTYRGHL 65
Query: 321 RPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
I RHG+ + R +FE TV L +AA E D L GV EN+++GQ P+GTG
Sbjct: 66 MAITRHGINRNDTGPMMRCSFEETVDILLDAAVYAETDYLRGVTENIMLGQLAPIGTG 123
>pir||T06754 DNA-directed RNA polymerase I 190K chain homolog F15B8.150 -
Arabidopsis thaliana >gi|4678281|emb|CAB41189.1|
(AL049660) DNA-directed RNA polymerase I 190K chain-like
protein [Arabidopsis thaliana]
Length = 1670
Score = 97.1 bits (238), Expect = 3e-19
Identities = 57/144 (39%), Positives = 88/144 (60%), Gaps = 5/144 (3%)
Query: 17 DLPESVKQ--ELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSI 74
DLP S+K+ E + + + NE+ E ++ V ++ +L +PGE VG +AAQS+
Sbjct: 1107 DLPISLKKGAEKFVEAMPMNERIASKFVRQEELLKLVKSKFFASLAQPGEPVGVLAAQSV 1166
Query: 75 GEPSTQMTLNTFHYAGVAEINVTLGLPRIIEI-VDARKNPSTPMMTVYLDEEHRYDREKA 133
GEPSTQMTLNTFH AG E+NVTLG+PR+ EI + A N TP+MT L + +E A
Sbjct: 1167 GEPSTQMTLNTFHLAGRGEMNVTLGIPRLQEILMTAAANIKTPIMTCPLLKGK--TKEDA 1224
Query: 134 EEVARRIEGTTLENLARTTTLDLI 157
++ R+ T+ ++ ++ L ++
Sbjct: 1225 NDITDRLRKITVADIIKSMELSVV 1248
Score = 90.9 bits (222), Expect = 2e-17
Identities = 45/121 (37%), Positives = 65/121 (53%)
Query: 268 TNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHG 327
+N+IH++ + G+EAAR II EI + + G+ V IRH+ L+AD MT G RP+ R G
Sbjct: 1550 SNSIHDMLNIFGVEAARETIIREINHVFKSYGISVSIRHLNLIADYMTFSGGYRPMSRMG 1609
Query: 328 VVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLTMKLP 387
+ E S R FE + + +AA GE D L + +G P GTG L ++
Sbjct: 1610 GIAESTSPFCRMTFETATKFIVQAATYGEKDTLETPSARICLGLPALSGTGCFDLMQRVE 1669
Query: 388 L 388
L
Sbjct: 1670 L 1670
>sp|O54889|RPA1_RAT DNA-DIRECTED RNA POLYMERASE I LARGEST SUBUNIT (RNA POLYMERASE I 194
KDA SUBUNIT) (RPA194) >gi|7514047|pir||T14103 probable
DNA-directed RNA polymerase (EC 2.7.7.6) I large chain -
rat >gi|2739050|gb|AAB94601.1| (AF025425) RNA polymerase
I 194 kDa subunit [Rattus norvegicus]
Length = 1716
Score = 96.0 bits (235), Expect = 7e-19
Identities = 66/186 (35%), Positives = 98/186 (52%), Gaps = 6/186 (3%)
Query: 207 FEKISDLRRLAEKVKKHRLKGLSG--VGKTIVRKEGDEYVIYTEGSNFKQVLKVPGV-DP 263
F+ S + LA + KG++ + +TI K E+V+ TEG N ++ K V D
Sbjct: 1534 FDMSSLVVSLAHNAIVYTTKGITRCLLNETINSKNEKEFVLNTEGINLPELFKYSEVLDL 1593
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
R +N+IH +A GIEAA I +EI + G+ VD RH+ LVAD M +GV +P+
Sbjct: 1594 RRLYSNDIHAVANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPL 1653
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
R G + +S L + FE + Q L +A G D L +++G+ V GTG+ +L
Sbjct: 1654 NRFG-IQSSSSPLQQMTFETSFQFLKQATMMGSHDELKSPSACLVVGKVVKGGTGLFEL- 1711
Query: 384 MKLPLR 389
K PLR
Sbjct: 1712 -KQPLR 1716
Score = 92.8 bits (227), Expect = 6e-18
Identities = 54/117 (46%), Positives = 77/117 (65%), Gaps = 8/117 (6%)
Query: 5 STIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGE 64
+++ EKK D QE + K + + +L+ + T++ +++R+L +PGE
Sbjct: 1164 ASVSETFEKKIDDY----SQEWAAQAEKSHNRSELSLDRLRTLLQ---LKWQRSLCDPGE 1216
Query: 65 AVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEI-VDARKNPSTPMMTV 120
AVG +AAQSIGEPSTQMTLNTFH+AG E+NVTLG+PR+ EI + A N TPMM+V
Sbjct: 1217 AVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSV 1273
>gi|7661686 DKFZP586M0122 protein [Homo sapiens] >gi|4096591|gb|AAC99959.1|
(U33460) DNA-directed RNA polymerase I, largest subunit
[Homo sapiens]
Length = 1717
Score = 94.8 bits (232), Expect = 1e-18
Identities = 53/102 (51%), Positives = 71/102 (68%), Gaps = 4/102 (3%)
Query: 20 ESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPST 79
+ QE + K EK +L+ + T++ +++R+L EPGEAVG +AAQSIGEPST
Sbjct: 1169 DDYSQEWAAQTEKSYEKSELSLDRLRTLLQ---LKWQRSLCEPGEAVGLLAAQSIGEPST 1225
Query: 80 QMTLNTFHYAGVAEINVTLGLPRIIEI-VDARKNPSTPMMTV 120
QMTLNTFH+AG E+NVTLG+PR+ EI + A N TPMM+V
Sbjct: 1226 QMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSV 1267
Score = 87.4 bits (213), Expect = 3e-16
Identities = 66/186 (35%), Positives = 96/186 (51%), Gaps = 7/186 (3%)
Query: 207 FEKISDLRRLAEKVKKHRLKGLSG--VGKTIVRKEGDEYVIYTEGSNFKQVLKVPGV-DP 263
F+ S + LA + KG++ + +T K E V+ TEG N ++ K V D
Sbjct: 1536 FDMSSLVVSLAHGAVIYATKGITRCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDL 1595
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
R +N+IH IA GIEA R I +EI + G+ VD RH+ LVAD M +GV +P+
Sbjct: 1596 RRLYSNDIHAIANTYGIEALR-VIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPL 1654
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
R G + +S L + FE + Q L +A G D L +++G+ V GTG+ +L
Sbjct: 1655 NRFG-IRSNSSPLQQMTFETSFQFLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFEL- 1712
Query: 384 MKLPLR 389
K PLR
Sbjct: 1713 -KQPLR 1717
>gb|AAD09356.1| (U33823) DNA-directed RNA polymerase I largest subunit [Homo
sapiens]
Length = 441
Score = 94.8 bits (232), Expect = 1e-18
Identities = 53/102 (51%), Positives = 71/102 (68%), Gaps = 4/102 (3%)
Query: 20 ESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPST 79
+ QE + K EK +L+ + T++ +++R+L EPGEAVG +AAQSIGEPST
Sbjct: 236 DDYSQEWAAQTEKSYEKSELSLDRLRTLLQ---LKWQRSLCEPGEAVGLLAAQSIGEPST 292
Query: 80 QMTLNTFHYAGVAEINVTLGLPRIIEI-VDARKNPSTPMMTV 120
QMTLNTFH+AG E+NVTLG+PR+ EI + A N TPMM+V
Sbjct: 293 QMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSV 334
>gi|11430046 DKFZP586M0122 protein [Homo sapiens]
Length = 601
Score = 94.8 bits (232), Expect = 1e-18
Identities = 53/102 (51%), Positives = 71/102 (68%), Gaps = 4/102 (3%)
Query: 20 ESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPST 79
+ QE + K EK +L+ + T++ +++R+L EPGEAVG +AAQSIGEPST
Sbjct: 49 DDYSQEWAAQTEKSYEKSELSLDRLRTLLQ---LKWQRSLCEPGEAVGLLAAQSIGEPST 105
Query: 80 QMTLNTFHYAGVAEINVTLGLPRIIEI-VDARKNPSTPMMTV 120
QMTLNTFH+AG E+NVTLG+PR+ EI + A N TPMM+V
Sbjct: 106 QMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSV 147
Score = 91.3 bits (223), Expect = 2e-17
Identities = 66/186 (35%), Positives = 96/186 (51%), Gaps = 6/186 (3%)
Query: 207 FEKISDLRRLAEKVKKHRLKGLSG--VGKTIVRKEGDEYVIYTEGSNFKQVLKVPGV-DP 263
F+ S + LA + KG++ + +T K E V+ TEG N ++ K V D
Sbjct: 419 FDMSSLVVSLAHGAVIYATKGITRCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDL 478
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
R +N+IH IA GIEAA I +EI + G+ VD RH+ LVAD M +GV +P+
Sbjct: 479 RRLYSNDIHAIANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPL 538
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
R G + +S L + FE + Q L +A G D L +++G+ V GTG+ +L
Sbjct: 539 NRFG-IRSNSSPLQQMTFETSFQFLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFEL- 596
Query: 384 MKLPLR 389
K PLR
Sbjct: 597 -KQPLR 601
>gi|6677793 RNA polymerase 1-4 (194 kDa subunit) [Mus musculus]
>gi|3914808|sp|O35134|RPA1_MOUSE DNA-DIRECTED RNA
POLYMERASE I LARGEST SUBUNIT (RNA POLYMERASE I 194 KDA
SUBUNIT) (RPA194) >gi|7513630|pir||T13961 DNA-directed
RNA polymerase (EC 2.7.7.6) I large chain - mouse
>gi|2330007|gb|AAB66718.1| (AF000938) RNA polymerase I
largest subunit [Mus musculus]
Length = 1717
Score = 93.2 bits (228), Expect = 4e-18
Identities = 65/186 (34%), Positives = 97/186 (51%), Gaps = 6/186 (3%)
Query: 207 FEKISDLRRLAEKVKKHRLKGLSG--VGKTIVRKEGDEYVIYTEGSNFKQVLKVPGV-DP 263
F+ S + LA K + KG++ + +T K E V+ TEG N ++ K + D
Sbjct: 1535 FDMSSLVVSLAHKAIVYTTKGITRCLLNETTNSKNEKELVLNTEGINLPELFKYSEILDL 1594
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
R +N+IH +A GIEAA I +EI + G+ VD RH+ LVAD M +GV +P+
Sbjct: 1595 RRLYSNDIHAMANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPL 1654
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
R G + +S L + FE + Q L +A G D L +++G+ V GTG+ +L
Sbjct: 1655 NRFG-IQSSSSPLQQMTFETSFQFLKQATMMGSHDELKSPSACLVVGKVVKGGTGLFEL- 1712
Query: 384 MKLPLR 389
K PLR
Sbjct: 1713 -KQPLR 1717
Score = 92.4 bits (226), Expect = 8e-18
Identities = 52/117 (44%), Positives = 74/117 (62%), Gaps = 8/117 (6%)
Query: 5 STIKSLIEKKGKDLPESVKQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGE 64
+++ EKK D + E + YK ++ ++ + + +++R+L +PGE
Sbjct: 1164 ASVSETFEKKIDDFSQ-------EWAAQAERSYKKSELSLDRLRTLLQLKWQRSLCDPGE 1216
Query: 65 AVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEI-VDARKNPSTPMMTV 120
AVG +AAQSIGEPSTQMTLNTFH+AG E NVTLG+PR+ EI + A N TPMM+V
Sbjct: 1217 AVGLLAAQSIGEPSTQMTLNTFHFAGRGETNVTLGIPRLREILMVASANIKTPMMSV 1273
>dbj|BAA82753.1| (AB018418) largest subunit of the DNA-dependent RNA polymerase [Red
sea bream iridovirus]
Length = 1159
Score = 92.1 bits (225), Expect = 1e-17
Identities = 94/387 (24%), Positives = 165/387 (42%), Gaps = 26/387 (6%)
Query: 1 MVSSSTIKSLIEKKGKDLPESVKQELYEK---LIKYNEKYKLTKAEVETIIDEVVKEYER 57
M + +S+ E+ P V+ + E+ +IK + ++ + EV Y R
Sbjct: 789 MDMAQAAQSVCERLAPIFPPLVRDSVMERHARIIKQGAA-QFPCSDADRWAQEVYDAYVR 847
Query: 58 ALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPM 117
AL PG VG V AQ+ G TQ TLN FH AG G R E+++ K S +
Sbjct: 848 ALCVPGSPVGIVCAQAFGARQTQSTLNIFHKAGGLH---DTGSMRFGELLNLSKKSSRRL 904
Query: 118 MTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGLTM 177
+ V+ E K +G + + +T + + + L + M
Sbjct: 905 LYVHALGEQTLSSVKDVLGNAFFKGPLQDFVVDSTD------DGVYTFNRAALFDRRIDM 958
Query: 178 EKVLKKLQSSFKSAEF--EMEGYTLIVRPKKFEKISDLRRLAEKVKKHRLKGLSGVGKTI 235
VL ++ S S ++ Y + K ++ SD V + G +
Sbjct: 959 CHVLNEINSKHGSCCTIEQLSEYVI-----KIQRCSDADGYLAGVF---VGGAPTICNVH 1010
Query: 236 VRKEGDEYVIYTEGSNFKQVLKVPGVDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTM 295
+++V GS L V GVD T NN+ ++ E G+ AA+ + ++ +
Sbjct: 1011 FVFNNNKWVAVVSGSTLLYALGVHGVDVDNTTCNNVWDVYEAKGLIAAKRFLTHSMVECL 1070
Query: 296 REQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERG 355
G +V + HI ++ D MT G+ + R+ + + +++A FE ++ L +A RG
Sbjct: 1071 ---GDDVHMAHIRVLVDRMTFSGLPTAVDRYTMRSCETGPISKATFEESLDILVSSAVRG 1127
Query: 356 EVDNLSGVIENVLIGQPVPVGTGMVKL 382
E DN +GV ++ G+ +P+GTG ++
Sbjct: 1128 ERDNNTGVGACLVAGKMLPLGTGSCRV 1154
>dbj|BAB15171.1| (AK025568) unnamed protein product [Homo sapiens]
Length = 495
Score = 91.3 bits (223), Expect = 2e-17
Identities = 66/186 (35%), Positives = 96/186 (51%), Gaps = 6/186 (3%)
Query: 207 FEKISDLRRLAEKVKKHRLKGLSG--VGKTIVRKEGDEYVIYTEGSNFKQVLKVPGV-DP 263
F+ S + LA + KG++ + +T K E V+ TEG N ++ K V D
Sbjct: 313 FDMSSLVVSLAHGAVIYATKGITRCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDL 372
Query: 264 TRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPI 323
R +N+IH IA GIEAA I +EI + G+ VD RH+ LVAD M +GV +P+
Sbjct: 373 RRLYSNDIHAIANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPL 432
Query: 324 GRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTGMVKLT 383
R G + +S L + FE + Q L +A G D L +++G+ V GTG+ +L
Sbjct: 433 NRFG-IRSNSSPLQQMTFETSFQFLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFEL- 490
Query: 384 MKLPLR 389
K PLR
Sbjct: 491 -KQPLR 495
>pir||JS0206 DNA-directed RNA polymerase (EC 2.7.7.6) I 189K chain - fission yeast
(Schizosaccharomyces pombe) >gi|4995|emb|CAA32887.1|
(X14783) nuc1 product, RNA polymerase I largest subunit
(AA 1-1689) [Schizosaccharomyces pombe]
Length = 1689
Score = 89.7 bits (219), Expect = 5e-17
Identities = 51/118 (43%), Positives = 76/118 (64%), Gaps = 14/118 (11%)
Query: 21 SVKQELYEKLIKYNEKY--KLTKAEVETIIDEVVKE-----------YERALVEPGEAVG 67
SV ++ + +Y +K KL ++ E+ +D+ + Y+++LV+PGE+VG
Sbjct: 1136 SVSEKFQRAVDEYTQKNPDKLIASKKESKLDDSLLNESKFKALMQLRYQQSLVDPGESVG 1195
Query: 68 TVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIV-DARKNPSTPMMTVYLDE 124
+A+QSIGEPSTQMTLNTFH+AG NVTLG+PR+ EI+ A N TP MT+ L++
Sbjct: 1196 VLASQSIGEPSTQMTLNTFHFAGFGAKNVTLGIPRLREIIMTASANIQTPTMTLRLND 1253
Score = 85.8 bits (209), Expect = 7e-16
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 14/220 (6%)
Query: 168 ERLEKSGLTMEKVL---KKLQSSFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHR 224
ER E T +++L K L + + E+ + +K +S + + + H
Sbjct: 1461 ERRELQLKTAKEILSNCKHLDFDYVNGEWATVELVFPINTEKLLMVSLVEKACSETVIHE 1520
Query: 225 LKGLSGVGKTIVRKEGDEYV-----IYTEGSNFKQVLKVPG-VDPTRTKTNNIHEIAEVL 278
+ G++ K D + + TEG N K + + + TN+I I +
Sbjct: 1521 IPGIT----RCFSKPPDSALDTVPKVITEGVNLKAIWEFYNEISMNDIYTNDIAAILRIY 1576
Query: 279 GIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLAR 338
G+EA RNAI+ E+ + G+ VD RH+ L+AD MT +G + R G + S A+
Sbjct: 1577 GVEATRNAIVHEVSSVFGVYGIAVDPRHLSLIADYMTFEGGYKAFNRMG-IEYNTSPFAK 1635
Query: 339 AAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
+FE T L EAA RG+VD+LS +++G+ GTG
Sbjct: 1636 MSFETTCHFLTEAALRGDVDDLSNPSSRLVVGRVGNFGTG 1675
>sp|P15398|RPA1_SCHPO DNA-DIRECTED RNA POLYMERASE I 190 KDA POLYPEPTIDE
>gi|82799|pir||JS0080 DNA-directed RNA polymerase (EC
2.7.7.6) I 189K chain - fission yeast
(Schizosaccharomyces pombe) >gi|7490483|pir||T40492
dna-directed rna polymerase i 190 kd polypeptide -
fission yeast (Schizosaccharomyces pombe)
>gi|173433|gb|AAA35326.1| (M37411) RNA polymerase I
largest subunit [Schizosaccharomyces pombe]
>gi|2832886|emb|CAA16827.1| (AL021730) dna-directed rna
polymerase i 190 kd polypeptide [Schizosaccharomyces
pombe]
Length = 1689
Score = 89.7 bits (219), Expect = 5e-17
Identities = 51/118 (43%), Positives = 76/118 (64%), Gaps = 14/118 (11%)
Query: 21 SVKQELYEKLIKYNEKY--KLTKAEVETIIDEVVKE-----------YERALVEPGEAVG 67
SV ++ + +Y +K KL ++ E+ +D+ + Y+++LV+PGE+VG
Sbjct: 1136 SVSEKFQRAVDEYTQKNPDKLIASKKESKLDDSLLNESKFKALMQLRYQQSLVDPGESVG 1195
Query: 68 TVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIV-DARKNPSTPMMTVYLDE 124
+A+QSIGEPSTQMTLNTFH+AG NVTLG+PR+ EI+ A N TP MT+ L++
Sbjct: 1196 VLASQSIGEPSTQMTLNTFHFAGFGAKNVTLGIPRLREIIMTASANIQTPTMTLRLND 1253
Score = 87.4 bits (213), Expect = 3e-16
Identities = 64/220 (29%), Positives = 104/220 (47%), Gaps = 14/220 (6%)
Query: 168 ERLEKSGLTMEKVL---KKLQSSFKSAEFEMEGYTLIVRPKKFEKISDLRRLAEKVKKHR 224
ER E T +++L K L + + E+ + +K +S + + + H
Sbjct: 1461 ERRELQLKTAKEILSNCKHLDFDYVNGEWATVELVFPINTEKLLMVSLVEKACSETVIHE 1520
Query: 225 LKGLSGVGKTIVRKEGDEYV-----IYTEGSNFKQVLKVPG-VDPTRTKTNNIHEIAEVL 278
+ G++ K D + + TEG N K + + + TN+I I +
Sbjct: 1521 IPGIT----RCFSKPPDSALDTVPKVITEGVNLKAIWEFYNEISMNDIYTNDIAAILRIY 1576
Query: 279 GIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLAR 338
G+EAARNAI+ E+ + G+ VD RH+ L+AD MT +G + R G + S A+
Sbjct: 1577 GVEAARNAIVHEVSSVFGVYGIAVDPRHLSLIADYMTFEGGYKAFNRMG-IEYNTSPFAK 1635
Query: 339 AAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGTG 378
+FE T L EAA RG+VD+LS +++G+ GTG
Sbjct: 1636 MSFETTCHFLTEAALRGDVDDLSNPSSRLVVGRVGNFGTG 1675
>pir||T19606 hypothetical protein Y48E1A.1 - Caenorhabditis elegans
>gi|5596641|emb|CAB05699.2| (Z83219) contains similarity
to Pfam domain: PF00623 (RNA polymerase alpha subunit),
Score=1071.7, E-value=0, N=1; PF01854 (RNA polymerase
A/beta/A subunit), Score=428.7, E-value=1.7e-125,
N=1~cDNA EST yk112e10.5 comes from this gene~cDNA EST
yk337b6.5> >gi|5596656|emb|CAB07687.2| (Z93392) contains
similarity to Pfam domain: PF00623 (RNA polymerase alpha
subunit), Score=1071.7, E-value=0, N=1; PF01854 (RNA
polymerase A/beta/A subunit), Score=428.7,
E-value=1.7e-125, N=1~cDNA EST yk112e10.5 comes from this
gene~cDNA EST yk337b6.5> >gi|5824819|emb|CAB54460.1|
(AL032648) contains similarity to Pfam domain: PF00623
(RNA polymerase alpha subunit), Score=1071.7, E-value=0,
N=1; PF01854 (RNA polymerase A/beta/A subunit),
Score=428.7, E-value=1.7e-125, N=1~cDNA EST yk112e10.5
comes from this gene~cDNA EST yk337b6>
Length = 1737
Score = 88.2 bits (215), Expect = 1e-16
Identities = 61/171 (35%), Positives = 96/171 (55%), Gaps = 22/171 (12%)
Query: 57 RALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEI-VDARKNPST 115
R+L +PGE VG +AAQSIGEPSTQMTLNTFH+AG E+NVTLG+PR+ EI + A K+ +T
Sbjct: 1226 RSLADPGENVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMTASKSIAT 1285
Query: 116 PMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLINMEFIVEIDPERLEKSGL 175
P ++ + R++ + + R ++ L+ L + +L+ EK L
Sbjct: 1286 PSASIAVIA--GTSRDRIDSIKRELDRVYLKQLLKNFSLE---------------EKITL 1328
Query: 176 TMEKVLKK--LQSSFKSAEFEMEGYTLIVRPKKFEKISD--LRRLAEKVKK 222
T + ++ L+ +AE G + R + E+I + R+A+ +KK
Sbjct: 1329 TQNQSCRRYHLRIDILAAEKRELGARHLKRSQIMEEIEKRFILRVAQAIKK 1379
Score = 88.2 bits (215), Expect = 1e-16
Identities = 73/259 (28%), Positives = 122/259 (46%), Gaps = 27/259 (10%)
Query: 163 VEIDPERLEKSGL-----TMEKVL---KKLQSSFKSAEFEMEGYTLIVRPKKFEKI---- 210
++ D E ++K GL T E +L ++QS + +E + YT V+ K+ ++
Sbjct: 1468 MDSDSEDVKKEGLDGEDQTTEPLLVNSSRIQSVQRLSE-NISSYTYDVKSNKWCEVVFEL 1526
Query: 211 -------SDLRRLAEKVKK----HRLKGLSGVGKTIVRKEGDEY-VIYTEGSNFKQVLKV 258
D+ + EK + H+ G+ +T +K G E ++ T+G N K
Sbjct: 1527 PLRNKTKMDVSSIVEKEVELFIVHQTPGIERCVETTEQKNGKEMTILQTQGVNLAAFFKH 1586
Query: 259 PGV-DPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADIMTLD 317
V D +N+++ I E G+EA AI E+ N G+EV RH+ L AD MT
Sbjct: 1587 ADVLDVNSVYSNDLNLILENYGVEACSKAITTEMNNVFAVYGIEVSKRHLSLTADYMTFT 1646
Query: 318 GVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPVPVGT 377
G ++P R G + +S L + FE T+ L EA GE DN++ +++G GT
Sbjct: 1647 GQIQPFNR-GAMSSSSSPLQKMTFETTMAFLREALLHGEEDNVNSPSARLVMGALPRGGT 1705
Query: 378 GMVKLTMKLPLRPQKEKEE 396
G L + ++ ++E+ E
Sbjct: 1706 GSFDLLLDTKMQSEREEHE 1724
>gb|AAA34890.1| (J03530) RNA polymerase A(I) large subunit [Saccharomyces cerevisiae]
Length = 1664
Score = 85.0 bits (207), Expect = 1e-15
Identities = 42/68 (61%), Positives = 52/68 (75%), Gaps = 1/68 (1%)
Query: 54 EYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIV-DARKN 112
+Y R+L+ PGEAVG +A+QS+GEPSTQMTLNTFH+AG NVTLG+PR+ EIV A
Sbjct: 1173 KYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFHFAGHGAANVTLGIPRLREIVMTASAA 1232
Query: 113 PSTPMMTV 120
TP MT+
Sbjct: 1233 IKTPQMTL 1240
Score = 81.5 bits (198), Expect = 1e-14
Identities = 83/374 (22%), Positives = 162/374 (43%), Gaps = 31/374 (8%)
Query: 32 KYNEKYKLTKAEVETII-DEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAG 90
+Y+E+Y ++K E++ +I ++ + E A+V+ + IG ++ +
Sbjct: 1301 EYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRTTGPDIGVAVPRLQTDV----- 1355
Query: 91 VAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLAR 150
N + R+ E D ++ V DE D ++ E + + + E +
Sbjct: 1356 ---ANSSSNSKRLEEDNDEEQSHKKTKQAVSYDEP---DEDEIETMREAEKSSDEEGIDS 1409
Query: 151 TTTLDLINMEFIVEIDPERLEKSGL----TMEKVLKKLQSSFKSAEFEMEGYTLIVRPKK 206
D + + V+++ E++ KS + M KV + QS+ S + Y K
Sbjct: 1410 DKESDSDSEDEDVDMN-EQINKSIVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGK 1468
Query: 207 F-----------EKISDLRRLAEKVKKHRLKGLSGVGKTI-VRKEGDEYVIYTEGSNFKQ 254
+ EK+ + + E +K ++ + + + + E + V+ TEG NF+
Sbjct: 1469 WCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQA 1528
Query: 255 VLKVPG-VDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADI 313
+ +D +N++ + + G+EAARN I+ EI N + V RH+ L+AD+
Sbjct: 1529 MWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADM 1588
Query: 314 MTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPV 373
MT G R G+ +S + + ++E T Q L +A E + L +++G+
Sbjct: 1589 MTRQGTYLAFNRQGMETSTSSFM-KMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLN 1647
Query: 374 PVGTGMVKLTMKLP 387
VGTG + K+P
Sbjct: 1648 NVGTGSFDVLAKVP 1661
>gi|6324917 RNA polymerase I subunit 190 (alpha); Rpa190p [Saccharomyces
cerevisiae] >gi|2507346|sp|P10964|RPA1_YEAST DNA-DIRECTED
RNA POLYMERASE I 190 KD POLYPEPTIDE (A190)
>gi|2131238|pir||S67250 DNA-directed RNA polymerase (EC
2.7.7.6) I 190K chain - yeast (Saccharomyces cerevisiae)
>gi|1199844|emb|CAA65029.1| (X95720) O6276 [Saccharomyces
cerevisiae] >gi|1420741|emb|CAA99665.1| (Z75249) ORF
YOR341w [Saccharomyces cerevisiae]
Length = 1664
Score = 85.0 bits (207), Expect = 1e-15
Identities = 42/68 (61%), Positives = 52/68 (75%), Gaps = 1/68 (1%)
Query: 54 EYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIV-DARKN 112
+Y R+L+ PGEAVG +A+QS+GEPSTQMTLNTFH+AG NVTLG+PR+ EIV A
Sbjct: 1173 KYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFHFAGHGAANVTLGIPRLREIVMTASAA 1232
Query: 113 PSTPMMTV 120
TP MT+
Sbjct: 1233 IKTPQMTL 1240
Score = 81.5 bits (198), Expect = 1e-14
Identities = 83/374 (22%), Positives = 162/374 (43%), Gaps = 31/374 (8%)
Query: 32 KYNEKYKLTKAEVETII-DEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAG 90
+Y+E+Y ++K E++ +I ++ + E A+V+ + IG ++ +
Sbjct: 1301 EYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRTTGPDIGVAVPRLQTDV----- 1355
Query: 91 VAEINVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLAR 150
N + R+ E D ++ V DE D ++ E + + + E +
Sbjct: 1356 ---ANSSSNSKRLEEDNDEEQSHKKTKQAVSYDEP---DEDEIETMREAEKSSDEEGIDS 1409
Query: 151 TTTLDLINMEFIVEIDPERLEKSGL----TMEKVLKKLQSSFKSAEFEMEGYTLIVRPKK 206
D + + V+++ E++ KS + M KV + QS+ S + Y K
Sbjct: 1410 DKESDSDSEDEDVDMN-EQINKSIVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGK 1468
Query: 207 F-----------EKISDLRRLAEKVKKHRLKGLSGVGKTI-VRKEGDEYVIYTEGSNFKQ 254
+ EK+ + + E +K ++ + + + + E + V+ TEG NF+
Sbjct: 1469 WCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQA 1528
Query: 255 VLKVPG-VDPTRTKTNNIHEIAEVLGIEAARNAIIEEIMNTMREQGLEVDIRHIMLVADI 313
+ +D +N++ + + G+EAARN I+ EI N + V RH+ L+AD+
Sbjct: 1529 MWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADM 1588
Query: 314 MTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLFEAAERGEVDNLSGVIENVLIGQPV 373
MT G R G+ +S + + ++E T Q L +A E + L +++G+
Sbjct: 1589 MTRQGTYLAFNRQGMETSTSSFM-KMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLN 1647
Query: 374 PVGTGMVKLTMKLP 387
VGTG + K+P
Sbjct: 1648 NVGTGSFDVLAKVP 1661
>pir||T28156 DNA-directed RNA polymerase homolog - malaria parasite (Plasmodium
falciparum) >gi|414322|gb|AAA72349.1| (L11172)
[Plasmodium falciparum RNA polymerase I gene, complete
cds.], gene product
Length = 2910
Score = 78.8 bits (191), Expect = 1e-13
Identities = 44/153 (28%), Positives = 75/153 (48%), Gaps = 4/153 (2%)
Query: 232 GKTIVRKEGDEYVIYTEGSNFKQVLKVPG--VDPTRTKTNNIHEIAEVLGIEAARNAIIE 289
GK I G EY + EG N ++ + +D T+ N+I+ I + GIEA R I +
Sbjct: 2754 GKDITHS-GAEYELQIEGKNIYKLYNIKDKYIDKTKLYCNDIYAIVKTYGIEAGRLCITK 2812
Query: 290 EIMNTMREQGLEVDIRHIMLVADIMTLDGVVRPIGRHGVVGEKASVLARAAFEITVQHLF 349
E+ G+++D RH+ ++D MT G ++ RHG +G +V + +FE L
Sbjct: 2813 ELKKVFDAYGIQIDFRHLSFISDFMTHTGDLKAFNRHG-LGYFRNVFHKMSFECATNFLI 2871
Query: 350 EAAERGEVDNLSGVIENVLIGQPVPVGTGMVKL 382
+ +D LS ++ G+ + VGT + +
Sbjct: 2872 QGCIHNSIDYLSTASSSLFFGKHIKVGTNLADI 2904
Score = 76.9 bits (186), Expect = 4e-13
Identities = 50/169 (29%), Positives = 87/169 (50%), Gaps = 3/169 (1%)
Query: 36 KYKLTKAEVETIIDEVVK-EYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
+Y+ +T+ ++K +Y +L PGE++G + AQS GEP+TQMTLNTFH AG
Sbjct: 2030 EYENVPMNFDTLSSSLLKSKYYNSLCNPGESIGILVAQSFGEPATQMTLNTFHLAGTE-- 2087
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTL 154
NVT+G+PR+ EI K S PM+ V + + + A ++ I + L+ ++
Sbjct: 2088 NVTMGIPRLKEIFLTSKLTSKPMIYVPIKLQVDNLKNDANKMKNYITSIADKILSSYKSI 2147
Query: 155 DLINMEFIVEIDPERLEKSGLTMEKVLKKLQSSFKSAEFEMEGYTLIVR 203
L ++ + + +D + + K +K L + E+ G T + +
Sbjct: 2148 FLTDVIYGIGVDRKIILKENQNEQKHTINLSDIINMNDEELSGDTQLAK 2196
>gb|AAC03136.2| (U90037) RNA polymerase II largest subunit [Limulus polyphemus]
Length = 387
Score = 77.3 bits (187), Expect = 3e-13
Identities = 48/184 (26%), Positives = 84/184 (45%), Gaps = 30/184 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+++L+ + ++ E+ +++A V+P AGV+
Sbjct: 195 EEFRLSSESFQWLLGEIEARFQQAQVQPXXXXXXXXXXXXXXXXXXXXXXXXXXAGVSAK 254
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT-- 152
NVTLG+PR+ EI++ K P TP +TV+L D EKA++V R+E TTL + T
Sbjct: 255 NVTLGVPRLKEIINISKKPKTPSLTVFLTGSAARDAEKAKDVLCRLEHTTLRKVTANTAI 314
Query: 153 --------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKKL 184
T+ + + EF+ +E+D +R+ LTME++ +K+
Sbjct: 315 YYDPDPQNTVIVEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEKI 374
Query: 185 QSSF 188
+ F
Sbjct: 375 NAGF 378
>gb|AAC03137.2| (U90038) RNA polymerase II largest subunit [Mastigoproctus
giganteus]
Length = 403
Score = 76.5 bits (185), Expect = 5e-13
Identities = 49/184 (26%), Positives = 83/184 (44%), Gaps = 30/184 (16%)
Query: 35 EKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEI 94
E+++L+ E ++ E+ +++A V+P AGV+
Sbjct: 211 EEFRLSSEAFEWLLGEIDTRFQQAQVQPXXXXXXXXXXXXXXXXXXXXXXXXXXAGVSAK 270
Query: 95 NVTLGLPRIIEIVDARKNPSTPMMTVYLDEEHRYDREKAEEVARRIEGTTLENLARTT-- 152
NVTLG+PR+ EI++ K P TP +TV+L D EKA++V R+E TTL + T
Sbjct: 271 NVTLGVPRLKEIINISKRPKTPSLTVFLTGAAARDAEKAKDVLCRLEHTTLRKVTANTAI 330
Query: 153 --------TLDLINMEFI--------------------VEIDPERLEKSGLTMEKVLKKL 184
T+ + EF+ +E+D +R+ LTME++ +K+
Sbjct: 331 YYDPDPQNTVIAEDQEFVNVYYEMPDFDPSRISPWLLRIELDRKRMTDKKLTMEQIAEKI 390
Query: 185 QSSF 188
+ F
Sbjct: 391 NAGF 394
>sp|P96177|RPOC_WEIHE DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TRANSCRIPTASE BETA' CHAIN)
(RNA POLYMERASE BETA' SUBUNIT)
>gi|1839048|emb|CAA65322.1| (X96470) DNA-dependent RNA
polymerase [Weissella hellenica]
Length = 1046
Score = 76.1 bits (184), Expect = 6e-13
Identities = 43/79 (54%), Positives = 52/79 (65%), Gaps = 5/79 (6%)
Query: 59 LVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMM 118
+VE GEAVGTVAAQSIGEP TQ+T+ TFH GVA ++T GLPR+ EI +AR M+
Sbjct: 846 VVEVGEAVGTVAAQSIGEPGTQLTMRTFHTGGVAGNDITQGLPRVQEIFEARNPKGRAMI 905
Query: 119 T-----VYLDEEHRYDREK 132
T V EE+ DR K
Sbjct: 906 TEVTGEVTTIEENPADRTK 924
>sp|P96178|RPOC_WEIPA DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TRANSCRIPTASE BETA' CHAIN)
(RNA POLYMERASE BETA' SUBUNIT)
>gi|1839050|emb|CAA65080.1| (X95813) DNA-dependent RNA
polymerase [Weissella paramesenteroides]
Length = 1054
Score = 76.1 bits (184), Expect = 6e-13
Identities = 45/98 (45%), Positives = 57/98 (57%), Gaps = 4/98 (4%)
Query: 59 LVEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMM 118
+VE GEAVGTVAAQSIGEP TQ+T+ TFH GVA ++T GLPR+ EI +AR M+
Sbjct: 846 VVEVGEAVGTVAAQSIGEPGTQLTMRTFHTGGVAGNDITQGLPRVQEIFEARNPKGRAMI 905
Query: 119 TVYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDL 156
T E + E A R + T++ T T L
Sbjct: 906 TEVTGEVTSIE----ENPADRTKEVTIQGETDTRTYTL 939
>pir||T10908 DNA-directed RNA polymerase (EC 2.7.7.6) beta' chain - Staphylococcus
aureus (fragment) >gi|1495791|emb|CAA61517.1| (X89233)
DNA-directed RNA polymerase [Staphylococcus aureus]
Length = 1057
Score = 75.7 bits (183), Expect = 8e-13
Identities = 43/103 (41%), Positives = 64/103 (61%), Gaps = 4/103 (3%)
Query: 60 VEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMT 119
VE GEAVGT+AAQSIGEP TQ+T+ TFH GVA ++T GLPRI EI +AR NP +
Sbjct: 917 VEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEAR-NPKGQAVI 975
Query: 120 VYLD---EEHRYDREKAEEVARRIEGTTLENLARTTTLDLINM 159
++ E+ + +++ +E+ + T LA T+ ++ +
Sbjct: 976 TEIEGVVEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVEI 1018
>sp|P47770|RPOC_STAAU DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TRANSCRIPTASE BETA' CHAIN)
(RNA POLYMERASE BETA' SUBUNIT)
Length = 1057
Score = 75.7 bits (183), Expect = 8e-13
Identities = 43/103 (41%), Positives = 64/103 (61%), Gaps = 4/103 (3%)
Query: 60 VEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMT 119
VE GEAVGT+AAQSIGEP TQ+T+ TFH GVA ++T GLPRI EI +AR NP +
Sbjct: 917 VEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEAR-NPKGQAVI 975
Query: 120 VYLD---EEHRYDREKAEEVARRIEGTTLENLARTTTLDLINM 159
++ E+ + +++ +E+ + T LA T+ ++ +
Sbjct: 976 TEIEGVVEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVEI 1018
>sp|P77839|RPOC_BROTH DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TRANSCRIPTASE BETA' CHAIN)
(RNA POLYMERASE BETA' SUBUNIT)
Length = 1053
Score = 74.1 bits (179), Expect = 2e-12
Identities = 48/98 (48%), Positives = 59/98 (59%), Gaps = 3/98 (3%)
Query: 60 VEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMT 119
VE GEAVG VAAQSIGEP TQ+T+ TFH GVA ++T GLPRI EI +AR NP +
Sbjct: 913 VEVGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEAR-NPKGHAVI 971
Query: 120 VYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLI 157
L E + EKA R I T + RT T+ ++
Sbjct: 972 TELTGEVKAIEEKANR-QREITVTGTQE-TRTYTVPMV 1007
>emb|CAA61515.1| (X89231) DNA-directed RNA polymerase [Brochothrix thermosphacta]
Length = 1053
Score = 74.1 bits (179), Expect = 2e-12
Identities = 48/98 (48%), Positives = 59/98 (59%), Gaps = 3/98 (3%)
Query: 60 VEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMT 119
VE GEAVG VAAQSIGEP TQ+T+ TFH GVA ++T GLPRI EI +AR NP +
Sbjct: 913 VEVGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEAR-NPKGHAVI 971
Query: 120 VYLDEEHRYDREKAEEVARRIEGTTLENLARTTTLDLI 157
L E + EKA R I T + RT T+ ++
Sbjct: 972 TELTGEVKAIEEKANR-QREITVTGTQE-TRTYTVPMV 1007
>sp|P16355|RPA1_TRYBB DNA-DIRECTED RNA POLYMERASE I LARGEST SUBUNIT >gi|84003|pir||S19264
DNA-directed RNA polymerase (EC 2.7.7.6) I largest chain
- Trypanosoma brucei >gi|10522|emb|CAA32572.1| (X14399)
RNA polymerase I largest subunit (AA 1 - 1744)
[Trypanosoma brucei]
Length = 1744
Score = 73.4 bits (177), Expect = 4e-12
Identities = 41/85 (48%), Positives = 56/85 (65%), Gaps = 2/85 (2%)
Query: 23 KQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMT 82
KQ+L E+L + +K+ A +T+ D + AL EPGE VG +AAQ+ GEPSTQMT
Sbjct: 1122 KQQLKERLQQRRQKW--VGAFEKTLADITARRRLWALCEPGEPVGLLAAQAAGEPSTQMT 1179
Query: 83 LNTFHYAGVAEINVTLGLPRIIEIV 107
LNTFH AG +VT G+PR+ E++
Sbjct: 1180 LNTFHTAGSTVSHVTEGIPRLRELL 1204
>pir||A34374 DNA-directed RNA polymerase (EC 2.7.7.6) I largest chain -
Trypanosoma brucei >gi|162219|gb|AAA30231.1| (M27164) RNA
polymerase I [Trypanosoma brucei]
Length = 1781
Score = 73.4 bits (177), Expect = 4e-12
Identities = 41/85 (48%), Positives = 56/85 (65%), Gaps = 2/85 (2%)
Query: 23 KQELYEKLIKYNEKYKLTKAEVETIIDEVVKEYERALVEPGEAVGTVAAQSIGEPSTQMT 82
KQ+L E+L + +K+ A +T+ D + AL EPGE VG +AAQ+ GEPSTQMT
Sbjct: 1159 KQQLKERLQQRRQKW--VGAFEKTLADITARRRLWALCEPGEPVGLLAAQAAGEPSTQMT 1216
Query: 83 LNTFHYAGVAEINVTLGLPRIIEIV 107
LNTFH AG +VT G+PR+ E++
Sbjct: 1217 LNTFHTAGSTVSHVTEGIPRLRELL 1241
>sp|P94892|RPOC_LEUME DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TRANSCRIPTASE BETA' CHAIN)
(RNA POLYMERASE BETA' SUBUNIT)
>gi|1838978|emb|CAA65077.1| (X95810) DNA-dependent RNA
polymerase [Leuconostoc mesenteroides]
Length = 989
Score = 72.6 bits (175), Expect = 7e-12
Identities = 63/151 (41%), Positives = 82/151 (53%), Gaps = 22/151 (14%)
Query: 20 ESVKQELYEKLIKYNEKYKLTKAEVETIIDE---VVKEYERAL-----VEPGEAVGTVAA 71
E + +++ +K++ K ++T V T E V +Y R L VE GEAVGTVAA
Sbjct: 800 EMIDEDVAKKIVNAGIK-EVTIRSVFTSTTEHGVSVLDYGRNLASGEEVEVGEAVGTVAA 858
Query: 72 QSIGEPSTQMTLNTFHYAGVAEIN-VTLGLPRIIEIVDA-----RKNPSTPMMTVYLDEE 125
QSIGEP TQ+T+ FH GVA N +T GLPR+ EIV+A R S T+ + EE
Sbjct: 859 QSIGEPGTQLTMRNFHTGGVAGGNDITQGLPRVQEIVEARIPKGRAEISEVTGTITVIEE 918
Query: 126 HRYDREKAEEVARRIEGTTLENLARTTTLDL 156
+ DR K+ IEG E RT TL L
Sbjct: 919 NPEDRAKSV----TIEG---ETDTRTYTLPL 942
>sp|P94899|RPOC_LEUPS DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TRANSCRIPTASE BETA' CHAIN)
(RNA POLYMERASE BETA' SUBUNIT)
>gi|1838980|emb|CAA65079.1| (X95812) DNA-dependent RNA
polymerase [Leuconostoc pseudomesenteroides]
Length = 989
Score = 72.6 bits (175), Expect = 7e-12
Identities = 61/155 (39%), Positives = 74/155 (47%), Gaps = 27/155 (17%)
Query: 25 ELYEKLIKYNEKYK--LTKAEVETIIDEV---------------VKEYERAL-----VEP 62
E EK++ NE + KA V I+EV V +Y R L VE
Sbjct: 790 ETGEKIVSRNEMIDEDVAKAIVNAGIEEVTIRSVFTSTTEHGVSVLDYGRNLASGEEVEV 849
Query: 63 GEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEIN-VTLGLPRIIEIVDARKNPSTPMMTVY 121
GEAVGTVAAQSIGEP TQ+T+ FH GVA N +T GLPR+ EIV+AR P
Sbjct: 850 GEAVGTVAAQSIGEPGTQLTMRNFHTGGVAGGNDITQGLPRVQEIVEAR----IPKGRAE 905
Query: 122 LDEEHRYDREKAEEVARRIEGTTLENLARTTTLDL 156
+ E E A R + T+E T T L
Sbjct: 906 ISEVTGVVTAIEENPAERTKAVTIEGETDTRTYTL 940
>sp|P77879|RPOC_LISIN DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TRANSCRIPTASE BETA' CHAIN)
(RNA POLYMERASE BETA' SUBUNIT)
Length = 1053
Score = 71.0 bits (171), Expect = 2e-11
Identities = 39/84 (46%), Positives = 51/84 (60%)
Query: 60 VEPGEAVGTVAAQSIGEPSTQMTLNTFHYAGVAEINVTLGLPRIIEIVDARKNPSTPMMT 119
VE GEAVG +AAQSIGEP TQ+T+ TFH GVA ++T GLPRI EI +AR ++T
Sbjct: 913 VEVGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRIQEIFEARNPKGQAIIT 972
Query: 120 VYLDEEHRYDREKAEEVARRIEGT 143
E + + + I+GT
Sbjct: 973 EVGGEVVSIEEGRDRQQEITIQGT 996
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.314 0.134 0.355
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 131710118
Number of Sequences: 2977
Number of extensions: 5357033
Number of successful extensions: 17611
Number of sequences better than 1.0e-10: 151
Number of HSP's better than 0.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 17252
Number of HSP's gapped (non-prelim): 262
length of query: 397
length of database: 189,106,746
effective HSP length: 63
effective length of query: 334
effective length of database: 151,402,065
effective search space: 50568289710
effective search space used: 50568289710
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (21.9 bits)
S2: 166 (69.1 bits)