BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0443 (NEAC) DE:chlorohydrolase, putative
(425 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||F75106 probable chlorohydrolase PAB0443 - Pyrococcus abyssi... 839 0.0
sp|O59184|YF15_PYRHO HYPOTHETICAL PROTEIN PH1515 >gi|7450801|pir... 620 e-176
sp|Q58936|YF41_METJA HYPOTHETICAL PROTEIN MJ1541 >gi|2129138|pir... 380 e-104
sp|O27549|YF05_METTH HYPOTHETICAL PROTEIN MTH1505 >gi|7450796|pi... 360 2e-98
gi|11498160 N-ethylammeline chlorohydrolase (trzA-1) [Archaeoglo... 338 9e-92
gi|11498602 N-ethylammeline chlorohydrolase (trzA-2) [Archaeoglo... 314 2e-84
sp|O66851|Y587_AQUAE HYPOTHETICAL PROTEIN AQ_587 >gi|7450799|pir... 293 3e-78
gb|AAG20370.1| (AE005110) N-ethylammeline chlorohydrolase; TrzA ... 273 3e-72
pir||H72315 conserved hypothetical protein - Thermotoga maritima... 259 4e-68
dbj|BAB05411.1| (AP001512) unknown conserved protein in others [... 254 1e-66
dbj|BAB04465.1| (AP001509) N-ethylammeline chlorohydrolase [Baci... 252 5e-66
emb|CAB57624.1| (Y18930) n-ethylammeline chlorohydrolase [Sulfol... 249 4e-65
gb|AAK40981.1| N-ethylammeline chlorohydrolase, putative (trzA) ... 249 4e-65
pir||B83249 conserved hypothetical protein PA3170 [imported] - P... 238 7e-62
gb|AAG19575.1| (AE005047) Vng1205c [Halobacterium sp. NRC-1] 233 4e-60
sp|Q92342|YDI4_SCHPO HYPOTHETICAL 50.4 KD PROTEIN C1F8.04C IN CH... 227 2e-58
pir||A82554 conserved hypothetical protein XF2472 [imported] - X... 219 4e-56
emb|CAC12188.1| (AL445066) chlorohydrolase related protein [Ther... 203 2e-51
sp|O31352|YOR3_BACCE HYPOTHETICAL PROTEIN (ORF3) >gi|11356509|pi... 195 9e-49
sp|P72156|ATZA_PSESD ATRAZINE CHLOROHYDROLASE >gi|11352844|pir||... 181 2e-44
pir||F83627 hypothetical protein PA0142 [imported] - Pseudomonas... 164 2e-39
gi|6753960 guanine deaminase [Mus musculus] >gi|9910725|sp|Q9R11... 152 1e-35
emb|CAB61315.1| (AL132997) putative hydrolase [Streptomyces coel... 149 5e-35
sp|Q9WTT6|GUAD_RAT GUANINE DEAMINASE (GUANASE) (GUANINE AMINASE)... 148 1e-34
gb|AAF63337.1|AF245172_1 (AF245172) guanine deaminase [Rattus no... 148 1e-34
gi|4758426 guanine deaminase; guanase [Homo sapiens] >gi|9910736... 140 3e-32
dbj|BAA86572.1| (AB033084) KIAA1258 protein [Homo sapiens] 140 3e-32
sp|Q52725|TRZA_RHOCO S-TRIAZINE HYDROLASE (N-ETHYLAMMELINE CHLOR... 134 1e-30
sp|O14057|GUAD_SCHPO PROBABLE GUANINE DEAMINASE (GUANASE) (GUANI... 134 1e-30
gb|AAF52167.1| (AE003607) CG18143 gene product [Drosophila melan... 133 4e-30
gb|AAC15070.1| (AF060075) SdeB [Myxococcus xanthus] 130 4e-29
gb|AAG23552.1|AF244603_1 (AF244603) N-ethylanimeline chlorohydro... 122 1e-26
sp|P76641|YGFP_ECOLI HYPOTHETICAL 50.2 KD PROTEIN IN KDUI-LYSS I... 116 5e-25
sp|Q9RYX4|GUAD_DEIRA PROBABLE GUANINE DEAMINASE (GUANASE) (GUANI... 116 5e-25
pir||G65071 hypothetical protein b2879 - Escherichia coli (strai... 116 6e-25
gb|AAA83064.1| (U28375) ORF_o439 [Escherichia coli] 116 6e-25
sp|Q46812|SSNA_ECOLI SSNA PROTEIN 116 6e-25
dbj|BAB03904.1| (AP001507) unknown conserved protein [Bacillus h... 116 6e-25
gi|6319963 Ydl238cp [Saccharomyces cerevisiae] >gi|2833210|sp|Q0... 111 2e-23
sp|P95442|ATZB_PSESD HYDROXYATRAZINE HYDROLASE >gi|1732206|gb|AA... 111 2e-23
pir||T49607 guanine deaminase (Gda) related protein [imported] -... 109 4e-23
pir||D83456 probable guanine deaminase PA1521 [imported] - Pseud... 106 4e-22
pir||H83628 probable guanine deaminase PA0134 [imported] - Pseud... 97 4e-19
sp|Q58110|Y699_METJA HYPOTHETICAL PROTEIN MJ0699 >gi|2128449|pir... 96 7e-19
emb|CAB89443.1| (AL354048) putative chlorohydrolase [Streptomyce... 94 4e-18
sp|O27075|Y994_METTH HYPOTHETICAL PROTEIN MTH994 >gi|7482754|pir... 88 2e-16
gb|AAC44523.1| (U38524) ORF1; Method: conceptual translation sup... 88 2e-16
pir||G81422 hypothetical protein Cj0067 [imported] - Campylobact... 87 3e-16
pir||F71956 hypothetical protein orf1 - Helicobacter pylori (str... 82 9e-15
pir||C64553 chlorohydrolase - Helicobacter pylori (strain 26695)... 82 2e-14
sp|Q9RW45|Y824_DEIRA HYPOTHETICAL PROTEIN DR0824 >gi|7473523|pir... 78 1e-13
pir||C83008 conserved hypothetical protein PA5106 [imported] - P... 75 1e-12
pir||T21966 hypothetical protein F38E11.3 - Caenorhabditis elega... 73 6e-12
pir||T46986 hypothetical protein [imported] - Yersinia pestis >g... 72 1e-11
>pir||F75106 probable chlorohydrolase PAB0443 - Pyrococcus abyssi (strain Orsay)
>gi|5458078|emb|CAB49567.1| (AJ248285) chlorohydrolase,
putative [Pyrococcus abyssi]
Length = 425
Score = 839 bits (2145), Expect = 0.0
Identities = 425/425 (100%), Positives = 425/425 (100%)
Query: 1 MVSLSVLLRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFI 60
MVSLSVLLRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFI
Sbjct: 1 MVSLSVLLRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFI 60
Query: 61 NAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFV 120
NAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFV
Sbjct: 61 NAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFV 120
Query: 121 DMYFHMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFI 180
DMYFHMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFI
Sbjct: 121 DMYFHMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFI 180
Query: 181 LAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLL 240
LAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLL
Sbjct: 181 LAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLL 240
Query: 241 NEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDG 300
NEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDG
Sbjct: 241 NEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDG 300
Query: 301 AASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLA 360
AASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLA
Sbjct: 301 AASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLA 360
Query: 361 DIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKVIDKFL 420
DIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKVIDKFL
Sbjct: 361 DIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKVIDKFL 420
Query: 421 EVSVA 425
EVSVA
Sbjct: 421 EVSVA 425
>sp|O59184|YF15_PYRHO HYPOTHETICAL PROTEIN PH1515 >gi|7450801|pir||G71027 probable
chlorohydrolase - Pyrococcus horikoshii
>gi|3257940|dbj|BAA30623.1| (AP000006) 391aa long
hypothetical chlorohydrolase [Pyrococcus horikoshii]
Length = 391
Score = 620 bits (1581), Expect = e-176
Identities = 291/391 (74%), Positives = 354/391 (90%)
Query: 34 VEVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVER 93
+EVKRNINK ADEV+D S SL+IP+FINAHTHSPMVI RGLAEDVPLM+WLQ YIWP ER
Sbjct: 1 MEVKRNINKAADEVIDASHSLIIPAFINAHTHSPMVIFRGLAEDVPLMDWLQNYIWPAER 60
Query: 94 KLRRKDVYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVGLRAYLGYGMVDLDDEE 153
KL+RK+VYWG+KLAL+EM HSG STFVDMYF+MEE+A+AT EVGLR +LGYGMVDL+DEE
Sbjct: 61 KLKRKEVYWGAKLALLEMVHSGISTFVDMYFYMEEVARATLEVGLRGFLGYGMVDLEDEE 120
Query: 154 KRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLA 213
KR+ E++ETEKL+EFI KL+S V FILAPHAPYTCS DCL+WV+EKSREW+SLVTIHLA
Sbjct: 121 KRRKEIKETEKLHEFITKLNSKLVKFILAPHAPYTCSLDCLKWVAEKSREWDSLVTIHLA 180
Query: 214 ETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPAS 273
ET+DEIKI+ EKYG+SPV+VL++ LLN+KLIAAHGIWLS +D+ ++S+ TIAHCPAS
Sbjct: 181 ETRDEIKIMEEKYGRSPVEVLKEANLLNDKLIAAHGIWLSKKDLEMLASSNVTIAHCPAS 240
Query: 274 NMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVKSE 333
NMKLGSG+FPM+ A++ ++NVALGTDGAASNNTLDI+REMRLASLLQKV +P+IVKSE
Sbjct: 241 NMKLGSGIFPMRDAIDEDINVALGTDGAASNNTLDIIREMRLASLLQKVNTLNPAIVKSE 300
Query: 334 DIFRMATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDT 393
+IFRMAT+NGAKAL LKAG+I EGY+ADIAVI+L+++HLLP+++PLA++IFSA+ GD+DT
Sbjct: 301 EIFRMATINGAKALKLKAGIIKEGYIADIAVINLKRSHLLPLHNPLATLIFSAKAGDIDT 360
Query: 394 LIVGGEIVMLDSELLTVDEEKVIDKFLEVSV 424
LIV G ++MLD E+LT+DEEKVIDKFL V +
Sbjct: 361 LIVSGRVIMLDGEVLTIDEEKVIDKFLGVGI 391
>sp|Q58936|YF41_METJA HYPOTHETICAL PROTEIN MJ1541 >gi|2129138|pir||D64492 N-ethylammeline
chlorohydrolase homolog - Methanococcus jannaschii
>gi|1592173|gb|AAB99560.1| (U67595) N-ethylammeline
chlorohydrolase (trzA) [Methanococcus jannaschii]
Length = 420
Score = 380 bits (965), Expect = e-104
Identities = 193/404 (47%), Positives = 274/404 (67%), Gaps = 6/404 (1%)
Query: 23 RADVLIEGDKIV---EVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVP 79
R D+LIEG+KI EVK+ + A E++D + IP IN HTH PM + RG+A+D+P
Sbjct: 13 RQDILIEGNKIKKIGEVKKEEIENA-EIIDGKNKIAIPGLINTHTHIPMTLFRGVADDLP 71
Query: 80 LMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVGLR 139
LMEWL YIWP+E KL + VYWG+ L IEM SGT+TF DMYF +E IAKA +E G+R
Sbjct: 72 LMEWLNNYIWPMEAKLNEEIVYWGTLLGCIEMIRSGTTTFNDMYFFLEGIAKAVDESGMR 131
Query: 140 AYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSE 199
A L YGM+DL DEE+R+ E++ EK +I L++S++ L PHAPYTCS + L V+
Sbjct: 132 AVLAYGMIDLFDEERRERELKNAEKYINYINSLNNSRIMPALGPHAPYTCSKELLMEVNN 191
Query: 200 KSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNE-KLIAAHGIWLSDEDIR 258
++++N + IHL ET DEIK+++EK G P L G ++ + IAAH + L+DE+I+
Sbjct: 192 LAKKYNVPIHIHLNETLDEIKMVKEKTGMEPFIYLNSFGFFDDVRAIAAHCVHLTDEEIK 251
Query: 259 KISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASL 318
+ ++H P SN+KL SGV P+ K L +NV LGTDG SNN L++ E++++++
Sbjct: 252 IMKQKNINVSHNPISNLKLASGVAPIPKLLAEGINVTLGTDGCGSNNNLNLFEEIKVSAI 311
Query: 319 LQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVNSP 378
L K ++ +P++VK+E+ F AT NGAKAL +KAG I EGYLADI +I+L K +L P +
Sbjct: 312 LHKGVNLNPTVVKAEEAFNFATKNGAKALNIKAGEIREGYLADIVLINLDKPYLYPKENI 371
Query: 379 LASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKVIDKFLEV 422
++ +++ A G VD +I+ G IVM D E+LTVDEEKV +K E+
Sbjct: 372 MSHLVY-AFNGFVDDVIIDGNIVMRDGEILTVDEEKVYEKAEEM 414
>sp|O27549|YF05_METTH HYPOTHETICAL PROTEIN MTH1505 >gi|7450796|pir||G69067
N-ethylammeline chlorohydrolase homolog -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2622622|gb|AAB85980.1| (AE000910) N-ethylammeline
chlorohydrolase homolog [Methanobacterium
thermoautotrophicum]
Length = 427
Score = 360 bits (914), Expect = 2e-98
Identities = 175/414 (42%), Positives = 273/414 (65%), Gaps = 3/414 (0%)
Query: 5 SVLLRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNINK-PADEVLDVSKSLVIPSFINAH 63
S+L+ G +L + R VLIE ++I +V ++ AD V+D + L+IP +N H
Sbjct: 5 SILITGPEILDAGGIR--RGSVLIEDNRIADVSNTLSPGDADTVIDGTGKLLIPGLVNTH 62
Query: 64 THSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMY 123
TH M + RG+A+D+PL WL ++IWP E +L Y G+ L IEM SGT++F DMY
Sbjct: 63 THLSMTLFRGIADDLPLDRWLNDHIWPAEARLNGDYCYAGALLGCIEMIRSGTTSFNDMY 122
Query: 124 FHMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAP 183
F+M+ +A+A EE GLR + +GM+DL D EK E+RE+ ++ + + ++ L P
Sbjct: 123 FYMDHVARAVEEAGLRCVISHGMIDLGDTEKMTAELRESRRIIKECHGMADDRIRVALGP 182
Query: 184 HAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEK 243
H+PYTCS + L+ + + + + ++ IH++ET++E+ + +G +PV+ L++VG+L +
Sbjct: 183 HSPYTCSEELLKETAALADKNDLMIHIHVSETENEVSEVSRSHGMTPVEYLDEVGVLGPR 242
Query: 244 LIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAAS 303
+AAH +WL D +I ++ ++H P+SNMKL SGV P+ + L+ VNV+LGTDGAAS
Sbjct: 243 TVAAHCVWLKDWEIDVLAERDVKVSHNPSSNMKLASGVSPVARLLQRGVNVSLGTDGAAS 302
Query: 304 NNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADIA 363
NN LD+ +EM+ ASLLQKV DP+ + + D+F MATLNGA+ALG+ AG+IA G LADI
Sbjct: 303 NNNLDMFQEMKTASLLQKVNLEDPTALPAMDVFSMATLNGARALGIDAGLIAPGKLADIV 362
Query: 364 VIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKVID 417
+++ R+ HL P +P + ++SA G DVDT+I G I++ D EL ++E+ V++
Sbjct: 363 ILNTRRPHLTPWRNPPSHTVYSASGADVDTVICDGRILLRDGELEVLEEKYVME 416
>gi|11498160 N-ethylammeline chlorohydrolase (trzA-1) [Archaeoglobus fulgidus]
>gi|3183226|sp|O29701|Y550_ARCFU HYPOTHETICAL PROTEIN
AF0550 >gi|7450797|pir||F69318 N-ethylammeline
chlorohydrolase (trzA-1) homolog - Archaeoglobus
fulgidus >gi|2650069|gb|AAB90684.1| (AE001066)
N-ethylammeline chlorohydrolase (trzA-1) [Archaeoglobus
fulgidus]
Length = 422
Score = 338 bits (857), Expect = 9e-92
Identities = 177/405 (43%), Positives = 262/405 (63%), Gaps = 6/405 (1%)
Query: 21 LTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPL 80
+ ++ +EG KI E+ K +D V+D S+ VIP F N HTH+ M + R A+D+ L
Sbjct: 15 IVEGNLKVEGKKISEIGGKAVK-SDVVIDGSRKAVIPGFFNTHTHAAMTLFRSYADDMQL 73
Query: 81 MEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVGLRA 140
EWL++ IWP+E KL K VYWG+KLA +EM SGT F DMYF E IA+A EE G+RA
Sbjct: 74 HEWLEKKIWPLEAKLDDKAVYWGTKLACVEMLKSGTVFFNDMYFFPEAIARAAEECGIRA 133
Query: 141 YLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEK 200
+ D + + ++ ++ K I+K D + + PHA YT S D LR +E
Sbjct: 134 CVSAAFFDFFNPDLLELNLKNAVKSLREIEKYDVLRA---IGPHAVYTVSLDGLRRAAEI 190
Query: 201 SREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKI 260
+ E + + HLAET+ E+ ++++GK V L+++G L+++LIAAH +WL D +I +
Sbjct: 191 AEEMDIFMHFHLAETEKEVLDFKKQHGKLIVQALDEIGFLSKRLIAAHSVWLEDAEIEIL 250
Query: 261 SSAGATIAHCPASNMKLGSGVFPMKKALEN-NVNVALGTDGAASNNTLDILREMRLASLL 319
+ G ++AHCPASNMKL G +A++ VN L TDGAASNN LD+L EM+ A+LL
Sbjct: 251 AKKGVSVAHCPASNMKLCVGKAIRYEAMKRAGVNFTLATDGAASNNNLDMLEEMKFAALL 310
Query: 320 QKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVNSPL 379
QK H +P+++K+E++F ATLNGAKA G+K+GVI EGY ADI ++DL K ++ P +S +
Sbjct: 311 QKFHHSNPTLLKAEEVFEAATLNGAKAFGIKSGVIKEGYEADIVLVDLAKPYMQPEHSLI 370
Query: 380 ASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEE-KVIDKFLEVS 423
A+++++A G VDT+IV GE+V+ + +EE K+I+K EV+
Sbjct: 371 ANLVYAASSGCVDTVIVKGEVVVEGGVFRSEEEELKIIEKANEVA 415
>gi|11498602 N-ethylammeline chlorohydrolase (trzA-2) [Archaeoglobus fulgidus]
>gi|3183234|sp|O29265|Y997_ARCFU HYPOTHETICAL PROTEIN
AF0997 >gi|7450798|pir||E69374 N-ethylammeline
chlorohydrolase (trzA-2) homolog - Archaeoglobus
fulgidus >gi|2649598|gb|AAB90244.1| (AE001035)
N-ethylammeline chlorohydrolase (trzA-2) [Archaeoglobus
fulgidus]
Length = 416
Score = 314 bits (795), Expect = 2e-84
Identities = 172/422 (40%), Positives = 256/422 (59%), Gaps = 17/422 (4%)
Query: 6 VLLRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFINAHTH 65
+++R GL ++ V ++G++I V + + + E+ D + LV+P NAHTH
Sbjct: 4 LVIRNGLCFINGEF--VECSVGVDGNRITHVAKEVERGEIEI-DAAGCLVMPGCFNAHTH 60
Query: 66 SPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFH 125
+ M +LRG AE +PL EWL++ +W VE +L VYWG+ LA +EM SG + F DMY H
Sbjct: 61 AAMTLLRGYAEGLPLREWLEK-VWEVEARLDEDAVYWGTMLACVEMLKSGVTAFADMYIH 119
Query: 126 MEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSS---KVNFILA 182
M+ +A+A E G+RA LGYGM D DEE+ + +E E EF +K + +V +LA
Sbjct: 120 MDAVAEAVGESGMRAVLGYGMADRGDEERAR---KELEIGLEFAEKWNGGFEGRVTTMLA 176
Query: 183 PHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNE 242
PHAPYTCS + L+ VS+ S++ L IH++ET E+K +RE+YGK PV+ L+ +G L+
Sbjct: 177 PHAPYTCSPEFLKVVSDASKDKGFLKHIHVSETLWEVKEVRERYGKRPVEFLDSIGFLDS 236
Query: 243 KLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAA 302
+ AH +WLS+ +++ ++ G ++AHCP SN+KL SG+ + + LE VNV +GTDGAA
Sbjct: 237 STVLAHAVWLSEAEMKILAERGVSVAHCPTSNLKLSSGIAKVSELLEMGVNVGIGTDGAA 296
Query: 303 SNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADI 362
SNN L +L + R+ +LLQ + R +K MAT G +A LK G I EGYLADI
Sbjct: 297 SNNMLSVLSDARVGALLQNLRGR---TLKPGHWLEMATEGGYRAYNLKGGRIEEGYLADI 353
Query: 363 AVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKVIDKFLEV 422
V + P++ P A + + +V G +VM D L+ V+EEKVI+K E
Sbjct: 354 VVFS-KTCRNAPMHDPAAMLYVENQALHA---VVDGVLVMEDGILVNVEEEKVIEKAEET 409
Query: 423 SV 424
++
Sbjct: 410 AL 411
>sp|O66851|Y587_AQUAE HYPOTHETICAL PROTEIN AQ_587 >gi|7450799|pir||G70352 N-ethylammeline
chlorohydrolase - Aquifex aeolicus
>gi|2983217|gb|AAC06815.1| (AE000697) N-ethylammeline
chlorohydrolase [Aquifex aeolicus]
Length = 430
Score = 293 bits (742), Expect = 3e-78
Identities = 146/396 (36%), Positives = 243/396 (60%), Gaps = 3/396 (0%)
Query: 25 DVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWL 84
D+ ++ KI ++ +NI A ++ + PSF N HTH M +LRGL D+PL +WL
Sbjct: 21 DIAVKDGKIEKIGKNIVGEAKYTINGKGKIAFPSFANMHTHISMTLLRGLGADLPLHDWL 80
Query: 85 QEYIWPVERKLRRKD-VYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVGLRAYLG 143
Q+ IWP+E + + V G+ L ++E SGT+ F+DMYF E +A+A E+VG+RA LG
Sbjct: 81 QKVIWPLEGEFVSPEFVKDGALLGIVESIRSGTTLFMDMYFFEEAVAEACEDVGIRAGLG 140
Query: 144 YGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNF-ILAPHAPYTCSFDCLRWVSEKSR 202
+G++D + + E ++ +F ++ + ++ F ++ PHAPYTCS + LR E +
Sbjct: 141 FGILDFPTKVAKTPE-EYIQRARKFAEEFKNRELVFPVICPHAPYTCSPNTLRMAKELAD 199
Query: 203 EWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISS 262
E+ L+ IH+AET++E++ I+E+YGK+PV+ LE +G L++ ++ AH +W ++++ +
Sbjct: 200 EYGLLLHIHVAETKEEVERIKEQYGKTPVEHLESIGFLDKNVLCAHMVWTTEKEREILKE 259
Query: 263 AGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKV 322
IAHCP SN+KL SG+ P+ ++ + V LGTDGAASN+ L++L E + K
Sbjct: 260 RDVKIAHCPESNLKLASGIAPVPDYVKRGITVTLGTDGAASNDNLNMLEETSTCAKFHKG 319
Query: 323 IHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVNSPLASI 382
+ D + + ++AT NG K G+KAG + EGY AD+ ++D P+ P++
Sbjct: 320 YNLDAKAIDAGTALKIATENGFKVAGIKAGKVEEGYEADLILVDTDFPEFQPLYDPISQF 379
Query: 383 IFSARGGDVDTLIVGGEIVMLDSELLTVDEEKVIDK 418
++SA +DT+I G+++M EL TVD+E++ K
Sbjct: 380 VYSANSECIDTVICKGKVLMEKRELKTVDQEEIFAK 415
>gb|AAG20370.1| (AE005110) N-ethylammeline chlorohydrolase; TrzA [Halobacterium sp.
NRC-1]
Length = 431
Score = 273 bits (691), Expect = 3e-72
Identities = 155/415 (37%), Positives = 233/415 (55%), Gaps = 2/415 (0%)
Query: 2 VSLSVLLRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFIN 61
+S ++ + GG VL+ D+ ++ DVL++ D + DE +D + LV+P +N
Sbjct: 1 MSDTLRVAGGAVLHP-DFTVSDGDVLVDRDAGEIIAVGDTPAGDETVDAAGCLVMPGLVN 59
Query: 62 AHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVD 121
AH H M +LRG A+D L WLQE IWP E +L D+ G++L L+EM +GT+ F D
Sbjct: 60 AHCHVAMTLLRGYADDKQLDAWLQEDIWPAEAELADGDIRAGARLGLVEMIRAGTTAFAD 119
Query: 122 MYFHMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKI-EMRETEKLYEFIKKLDSSKVNFI 180
MYF + E+ A E GLRA +G+G+V + ++ + + E + ++
Sbjct: 120 MYFEVPEVVDAITEAGLRARVGHGVVTVGKDDADAVADNEEALSVAREFNDAADGRITSA 179
Query: 181 LAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLL 240
PH+ T + LR +RE + V H ET+ E++ I +++G P++ DVGLL
Sbjct: 180 YMPHSLTTVGEEYLREFVAAAREADVPVHFHANETEQEVEPIVDEHGSRPLEYAADVGLL 239
Query: 241 NEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDG 300
E AHG+ + +I ++ +GA++ HCPASNMKL SG+ P++ E V VALGTDG
Sbjct: 240 AEDDFLAHGVHTTAGEIELLAESGASVVHCPASNMKLASGMAPVQAMREAGVTVALGTDG 299
Query: 301 AASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLA 360
AASNN LD+ E+R A++L K+ V + MAT GA ALG +G I G A
Sbjct: 300 AASNNDLDVFDELRDAAMLGKLQTGAADAVPARAAVEMATAGGAAALGFDSGRIEVGANA 359
Query: 361 DIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKV 415
D+AV+D HL PV+ ++ + ++A G DV I GE++M D E+L DE V
Sbjct: 360 DLAVVDFDAPHLTPVHDHVSHLAYAATGQDVRHTICDGEVLMRDREVLPFDEAAV 414
>pir||H72315 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
>gi|4981474|gb|AAD36017.1|AE001757_10 (AE001757)
conserved hypothetical protein [Thermotoga maritima]
Length = 406
Score = 259 bits (655), Expect = 4e-68
Identities = 151/380 (39%), Positives = 228/380 (59%), Gaps = 15/380 (3%)
Query: 36 VKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKL 95
+KR + LD+S LV+P+ N HTH+PM +LRG+AED+ EWL + P+E +L
Sbjct: 28 IKRVLQGEVKVDLDLSGKLVMPALFNTHTHAPMTLLRGVAEDLSFEEWLFSKVLPIEDRL 87
Query: 96 RRKDVYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVGLRAYLGYGMVDLDDEEKR 155
K Y+G+ LA +EMA G + FVDMYFH E IAKA + G+RA L G+VD + ++
Sbjct: 88 TEKMAYYGTILAQMEMARHGIAGFVDMYFHEEWIAKAVRDFGMRALLTRGLVDSNGDDGG 147
Query: 156 KIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAET 215
++E E KLY + ++ PH+PY CS + L+ V + ++ N+ VTIHL ET
Sbjct: 148 RLE--ENLKLYNEWNGFE-GRIFVGFGPHSPYLCSEEYLKRVFDTAKSLNAPVTIHLYET 204
Query: 216 QDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNM 275
+E+Y D+L ++GL K IAAH + L + + ++H PASN+
Sbjct: 205 S------KEEYDLE--DIL-NIGLKEVKTIAAHCVHLPERYFGVLKDIPFFVSHNPASNL 255
Query: 276 KLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDI 335
KLG+G+ P+++ +E+ + V LGTDGAASNN+L++ EMRLASLLQK ++P +
Sbjct: 256 KLGNGIAPVQRMIEHGMKVTLGTDGAASNNSLNLFFEMRLASLLQKA--QNPRNLDVNTC 313
Query: 336 FRMATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLI 395
+M T +GA+A+G K+G I EG+ AD+ VIDL + PV + + + + A G+V +
Sbjct: 314 LKMVTYDGAQAMGFKSGKIEEGWNADLVVIDLDLPEMFPVQN-IKNHLVHAFSGEVFATM 372
Query: 396 VGGEIVMLDSELLTVDEEKV 415
V G+ + D E T+D E+V
Sbjct: 373 VAGKWIYFDGEYPTIDSEEV 392
>dbj|BAB05411.1| (AP001512) unknown conserved protein in others [Bacillus
halodurans]
Length = 428
Score = 254 bits (642), Expect = 1e-66
Identities = 144/391 (36%), Positives = 228/391 (57%), Gaps = 8/391 (2%)
Query: 33 IVEVKRNINKPAD----EVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYI 88
IV V P + EV+D V+P IN H H M +LRG ++D+PL WL E +
Sbjct: 22 IVSVAEGTPSPEEIDRVEVIDGKGKWVMPGMINTHGHLGMSLLRGHSDDLPLQSWLTEKM 81
Query: 89 WPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMY-FHMEEIAKATEEVGLRAYLGYGMV 147
WP E K+ R+ V+ +LA+ EM SGT+TF++MY +M+++A+A E G RA L M+
Sbjct: 82 WPFEGKMDREAVHHARQLAMAEMIKSGTTTFLEMYHLYMDDLAEAVVEQGPRAVLMRSMI 141
Query: 148 DLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSL 207
L E +++ +++E + ++ ++APHAPYTC + + +++ +
Sbjct: 142 GLCSESEQREKLKEAVTFATTWNGDGNGRITTMMAPHAPYTCPPSFIEMIVDEADRIDLP 201
Query: 208 VTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEK-LIAAHGIWLSDEDIRKISSAGAT 266
+ H+AETQ E++ R+ YG P+ E +G L ++ + AH + L +E++ + +
Sbjct: 202 LHTHMAETQREVEEHRKTYGVHPLVHFEQLGFLKDRHWLLAHCVHLGEEELDILEQHPSV 261
Query: 267 -IAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHR 325
++H P SN+KLGSG+ ++ LE +N+ LGTD ASNN LD++ EMR+A+LLQK
Sbjct: 262 HVSHNPMSNLKLGSGIANVQSMLERGINICLGTDSVASNNHLDLVEEMRIAALLQKGAVL 321
Query: 326 DPSIVKSEDIFRMATLNGAKALGL-KAGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIF 384
DP+ + +E MAT NGAKAL L + G I G AD +ID + HL P ++ +++
Sbjct: 322 DPTAIPAETAIAMATKNGAKALRLPQVGTIEAGKRADFIMIDPQCLHLQPHEHVMSHLVY 381
Query: 385 SARGGDVDTLIVGGEIVMLDSELLTVDEEKV 415
+ +G DV + V G +ML+ EL T DEEK+
Sbjct: 382 ALKGADVQDVFVEGAPLMLNKELKTFDEEKL 412
>dbj|BAB04465.1| (AP001509) N-ethylammeline chlorohydrolase [Bacillus halodurans]
Length = 445
Score = 252 bits (637), Expect = 5e-66
Identities = 137/405 (33%), Positives = 234/405 (56%), Gaps = 14/405 (3%)
Query: 25 DVLIEGDKIVEVKRNINKPA-DEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEW 83
D+LI+ I + +++++ ++V+D + VIP F+ H H + RG +D+ LM+W
Sbjct: 24 DLLIKDGLICAIGQDLSEEGVEKVIDATGRTVIPGFVQTHIHLCQTLFRGKGDDLELMDW 83
Query: 84 LQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDM--YFHMEEIAKATEEVGLRAY 141
L++ IWP+E + +Y+ + L + E+ SGT+T VDM H + A G+RA
Sbjct: 84 LKKRIWPLEAAHDSESIYYSALLGIGELIESGTTTIVDMETVHHTDSAFAAIASSGIRAI 143
Query: 142 LGYGMVDLDDE------EKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLR 195
G M+D +E EK + ++ +L E D ++ + +P +C+ + LR
Sbjct: 144 SGKVMMDKGEEVPLPLQEKTAQSIEKSIELLEEWHSFDGGRIRYAFSPRFVVSCTEELLR 203
Query: 196 WVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDE 255
V + S + V H +E + EI++++++ G ++ L+ VGL NE+LI AH IWLS+
Sbjct: 204 EVGKLSAHYQVHVHTHASENRGEIEMVQQETGMRNIEYLDHVGLANERLILAHCIWLSEN 263
Query: 256 DIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRL 315
+ R I G ++HCP SN+KL SG+ + L+ + V+LG DGA NN LD+ EMRL
Sbjct: 264 EKRIIKERGIHVSHCPGSNLKLASGIADIPGLLDQAIPVSLGADGAPCNNNLDMFNEMRL 323
Query: 316 ASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGL--KAGVIAEGYLADIAVIDLRKAHLL 373
A+L+QK +H P+ + + +F+MAT+NGA+A+G+ + G + G AD+A+++LR H
Sbjct: 324 AALIQKPVH-GPTAMDARTVFKMATINGARAIGMDQEIGSLEVGKKADLAILNLRHFHTY 382
Query: 374 PV--NSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKVI 416
P P++ I++SA DV+T ++ G +VM + + T+D V+
Sbjct: 383 PSFDVDPISRIVYSATRADVETTMINGRVVMENRVMKTIDPAIVL 427
>emb|CAB57624.1| (Y18930) n-ethylammeline chlorohydrolase [Sulfolobus solfataricus]
Length = 411
Score = 249 bits (630), Expect = 4e-65
Identities = 147/385 (38%), Positives = 230/385 (59%), Gaps = 19/385 (4%)
Query: 18 DYKLTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAED 77
D L +++I+ I V R + DEV D S+ + IP +NAHTH+PM+ILRG +D
Sbjct: 20 DKILENVNIVIQNGYIKNVGREVE--GDEV-DCSEYIAIPGLVNAHTHTPMIILRGYYDD 76
Query: 78 VPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVG 137
L EWL++ IW E+ + ++ S+LA++EM GT+ F+DMYF+ E + + E+ G
Sbjct: 77 AELTEWLKK-IWEFEKVFKLNEMNIASELAIMEMLSKGTTAFIDMYFNPEGVKEIAEKYG 135
Query: 138 LRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWV 197
+RAY GY ++ E E +K +K + K I+ H+ Y+ S + L+
Sbjct: 136 IRAYAGYTFLN------SLFEPHEIDKKQRQLKTSELFKP--IVNVHSIYSTSIETLKLA 187
Query: 198 SEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDI 257
+ + E ++ + IH++ET+ EI I++KYGK PV++L ++G++ + G W+++ ++
Sbjct: 188 KQIAEETDTWIHIHVSETRSEIYEIKKKYGKFPVELLNELGIVKNAQLVHLG-WIANWEL 246
Query: 258 RKISSAGATIAHCPASNMKLGS-GVFPMKKALENNVNVALGTDGAASNNTLDILREMRLA 316
R ++ A HCP SNMKL + G FP K+ +EN VN+ +GTDGAASNN+LD+ REM+ A
Sbjct: 247 RYVNQA----THCPTSNMKLATAGFFPFKELMENGVNITIGTDGAASNNSLDMFREMKNA 302
Query: 317 SLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVN 376
LLQ+ + D VK+ FR AT NG K + LK G I EGY+ADI ++ K + L +
Sbjct: 303 VLLQRHSYWDVG-VKAFHAFRAATENGYKLINLKGGRIEEGYIADIVLLKKDKLYPLRKD 361
Query: 377 SPLASIIFSARGGDVDTLIVGGEIV 401
L++I++ G V +IV G IV
Sbjct: 362 RILSNIVYYTVGEYVGKVIVNGRIV 386
>gb|AAK40981.1| N-ethylammeline chlorohydrolase, putative (trzA) [Sulfolobus
solfataricus]
Length = 411
Score = 249 bits (630), Expect = 4e-65
Identities = 147/385 (38%), Positives = 230/385 (59%), Gaps = 19/385 (4%)
Query: 18 DYKLTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAED 77
D L +++I+ I V R + DEV D S+ + IP +NAHTH+PM+ILRG +D
Sbjct: 20 DKILENVNIVIQNGYIKNVGREVE--GDEV-DCSEYIAIPGLVNAHTHTPMIILRGYYDD 76
Query: 78 VPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVG 137
L EWL++ IW E+ + ++ S+LA++EM GT+ F+DMYF+ E + + E+ G
Sbjct: 77 AELTEWLKK-IWEFEKVFKLNEMNIASELAIMEMLSKGTTAFIDMYFNPEGVKEIAEKYG 135
Query: 138 LRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWV 197
+RAY GY ++ E E +K +K + K I+ H+ Y+ S + L+
Sbjct: 136 IRAYAGYTFLN------SLFEPHEIDKKQRQLKTSELFKP--IVNVHSIYSTSIETLKLA 187
Query: 198 SEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDI 257
+ + E ++ + IH++ET+ EI I++KYGK PV++L ++G++ + G W+++ ++
Sbjct: 188 KQIAEETDTWIHIHVSETRSEIYEIKKKYGKFPVELLNELGIVKNAQLVHLG-WIANWEL 246
Query: 258 RKISSAGATIAHCPASNMKLGS-GVFPMKKALENNVNVALGTDGAASNNTLDILREMRLA 316
R ++ A HCP SNMKL + G FP K+ +EN VN+ +GTDGAASNN+LD+ REM+ A
Sbjct: 247 RYVNQA----THCPTSNMKLATAGFFPFKELMENGVNITIGTDGAASNNSLDMFREMKNA 302
Query: 317 SLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVN 376
LLQ+ + D VK+ FR AT NG K + LK G I EGY+ADI ++ K + L +
Sbjct: 303 VLLQRHSYWDVG-VKAFHAFRAATENGYKLINLKGGRIEEGYIADIVLLKKDKLYPLRKD 361
Query: 377 SPLASIIFSARGGDVDTLIVGGEIV 401
L++I++ G V +IV G IV
Sbjct: 362 RILSNIVYYTVGEYVGKVIVNGRIV 386
>pir||B83249 conserved hypothetical protein PA3170 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949287|gb|AAG06558.1|AE004741_3 (AE004741)
conserved hypothetical protein [Pseudomonas aeruginosa]
Length = 444
Score = 238 bits (602), Expect = 7e-62
Identities = 136/383 (35%), Positives = 218/383 (56%), Gaps = 7/383 (1%)
Query: 44 ADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKD-VYW 102
A E+ ++ L+ P +NAH HS M + RGLA+D+PLM WLQ++IWP E + +D +
Sbjct: 53 ATEIRELPGMLLAPGLVNAHGHSAMSLFRGLADDLPLMTWLQDHIWPAEGQWVSEDFIRD 112
Query: 103 GSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIE--MR 160
G++LA+ E G + F DMYF+ + I + G+RA + ++D R +R
Sbjct: 113 GTELAIAEQVKGGITCFSDMYFYPQAICGVVHDSGVRAQVAIPVLDFPIPGARDSAEAIR 172
Query: 161 ETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIK 220
+ L++ +K ++ F PHAPYT S D L + + E ++ + +H+ ET E++
Sbjct: 173 QGMALFDDLKHHPRIRIAF--GPHAPYTVSDDKLEQILVLTEELDASIQMHVHETAFEVE 230
Query: 221 IIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSG 280
E+ G+ P+ L +GLL + A H + ++D+ + +++ HCP SN+KL SG
Sbjct: 231 QAMERNGERPLARLHRLGLLGPRFQAVHMTQVDNDDLAMLVETNSSVIHCPESNLKLASG 290
Query: 281 VFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMAT 340
P++K + VNVA+GTDGAASNN LD+L E R A+LL K ++ + + + RMAT
Sbjct: 291 FCPVEKLWQAGVNVAIGTDGAASNNDLDLLGETRTAALLAKAVYGQATALDAHRALRMAT 350
Query: 341 LNGAKALGLK--AGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGG 398
LNGA+ALGL+ G + G AD+ DL PV P++ +I+++ V + VGG
Sbjct: 351 LNGARALGLERLIGSLEAGKAADLVAFDLSGLAQQPVYDPVSQLIYASGRDCVRHVWVGG 410
Query: 399 EIVMLDSELLTVDEEKVIDKFLE 421
++ D LL DE+++I + E
Sbjct: 411 RQLLDDGRLLRHDEQRLIARARE 433
>gb|AAG19575.1| (AE005047) Vng1205c [Halobacterium sp. NRC-1]
Length = 431
Score = 233 bits (587), Expect = 4e-60
Identities = 141/426 (33%), Positives = 218/426 (51%), Gaps = 13/426 (3%)
Query: 7 LLRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNIN----KPADEVLDVSKSLVIPSFINA 62
LL V+ D L V++ D+I V P E +DV ++ P + A
Sbjct: 3 LLTADTVVQDADRVLQDGAVVVVDDRITAVGDRAALADAHPDHERIDVD--VLAPGLVGA 60
Query: 63 HTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDM 122
H HS + RG+A+D L++WL +++ P+E L ++ + LA +E SGT+ VD
Sbjct: 61 HVHSVQSLGRGIADDQELLDWLFDHVLPMEAGLDAAEMRAAADLAYLEFVESGTTGVVDH 120
Query: 123 YF--HMEEIAKATEEVGLRAYLGYGMVDLDD----EEKRKIEMRETEKLYEFIKKLDSSK 176
H E A + G+RA LG ++D D +E + ETE L +
Sbjct: 121 LSVDHAGEAFGAAADSGVRARLGKVLMDKDSPDGLQEDTDAALAETEALIREWDGACDGR 180
Query: 177 VNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLED 236
+ + + P +C+ CLR + E+ + H +E Q EI+ + + GK + L+D
Sbjct: 181 IQYAITPRFAVSCTEACLRGCRALADEYGVRIHTHASENQGEIETVETETGKRNIHWLDD 240
Query: 237 VGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVAL 296
VGL E ++ AH +W D + ++ G + HCP+SNMKL SGV P+ E +NVAL
Sbjct: 241 VGLTGEDVVLAHCVWTDDSERALLAETGTHVTHCPSSNMKLASGVAPVADYRERGINVAL 300
Query: 297 GTDGAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLK-AGVIA 355
GTDG NNTLD EMR ASLL KV DP+ + + +F MAT NGAKA G + G IA
Sbjct: 301 GTDGPPCNNTLDGFAEMRQASLLGKVDALDPTALPARSVFEMATHNGAKAAGFENVGRIA 360
Query: 356 EGYLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKV 415
EG+ AD+ + A P++ P + ++++A G DV +V G+++ D + +D +
Sbjct: 361 EGWTADLVGLSTDAARSTPIHDPYSHLVYAAHGDDVTLTMVAGDVLYRDGAHVRMDAPAI 420
Query: 416 IDKFLE 421
++ E
Sbjct: 421 RERARE 426
>sp|Q92342|YDI4_SCHPO HYPOTHETICAL 50.4 KD PROTEIN C1F8.04C IN CHROMOSOME I
>gi|7490142|pir||T38111 atrazine chlorohydrolase -
fission yeast (Schizosaccharomyces pombe)
>gi|1638851|emb|CAB03598.1| (Z81312) atrazine
chlorohydrolase [Schizosaccharomyces pombe]
Length = 463
Score = 227 bits (572), Expect = 2e-58
Identities = 143/427 (33%), Positives = 230/427 (53%), Gaps = 35/427 (8%)
Query: 25 DVLIEGDKIVEVKRN----INK--------PADEVLDVSKSLVIPSFINAHTHSPMVILR 72
D+LI+G +V+ N I K P ++ + +V+P I+ H H +LR
Sbjct: 16 DILIDGAILVKDGSNTIDDIGKTDRLVSIYPNEKHKSLEGHIVMPGLISLHVHLAQSLLR 75
Query: 73 GLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFH----MEE 128
A+D+PL+ WL + +W ++ ++D Y S+L + EM SGT+TFV+ F +E
Sbjct: 76 SAADDLPLISWLCDTVWKMQGNFTQEDGYVASQLTIAEMLKSGTTTFVEALFAQRYGIEG 135
Query: 129 IAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSS------------- 175
KA E G+R +G ++D + + E L E L+ +
Sbjct: 136 AVKAVIESGIRGCIGKVVMD-QPRYATQTGVSMHEGLIENSNSLNQAVESHSKFHGKGNG 194
Query: 176 KVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLE 235
+V P S + R + + +R N +T+H AE + + + K +P+ +
Sbjct: 195 RVEIWFGARTPGGVSEELYRKMVKIARANNIGITMHCAEVKADREFFASKE-HTPMTYCK 253
Query: 236 DVGLLNEKLIAAHGIWLSDEDIRKISSAG--ATIAHCPASNMKLGSGVFPMKKALENNVN 293
D+GLL K + AH + L +D+ + G ++AHCP SN KLGSG+ P+K+ LE ++
Sbjct: 254 DLGLLGPKTVLAHMVHLDTQDLEILEKHGNGTSVAHCPVSNSKLGSGIAPLKEMLEKSII 313
Query: 294 VALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGL-KAG 352
V +G DG NNT+D+L+EM++ASLL K +H DPSIV +E I MAT+NGAKALG G
Sbjct: 314 VGIGCDGCPCNNTMDLLQEMKMASLLPKALHGDPSIVPAEKIVEMATINGAKALGRDDLG 373
Query: 353 VIAEGYLADIAVIDL-RKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVD 411
+ G AD +DL K + P+ ++++++ A G DV T+++ G++++ D LLT+D
Sbjct: 374 SLEVGKKADFISLDLSNKLYAQPLRDLVSAVVYIATGADVATVVIDGKLIVEDHVLLTID 433
Query: 412 EEKVIDK 418
E K+IDK
Sbjct: 434 EPKLIDK 440
>pir||A82554 conserved hypothetical protein XF2472 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9107669|gb|AAF85270.1|AE004055_8 (AE004055)
conserved hypothetical protein [Xylella fastidiosa]
Length = 435
Score = 219 bits (553), Expect = 4e-56
Identities = 130/378 (34%), Positives = 209/378 (54%), Gaps = 19/378 (5%)
Query: 52 KSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKD-VYWGSKLALIE 110
++ ++P +NAHTH+PM +LRG+A+D+PLM WLQ++IWPVE + + V G+ LA+ E
Sbjct: 53 EAALLPGLVNAHTHNPMTLLRGMADDLPLMTWLQQHIWPVETAVIGPEFVGDGTALAIAE 112
Query: 111 MAHSGTSTFVDMYFHMEEIAKATEEVGLRAYLGYGMVDL-------DDEE-KRKIEMRET 162
M GT+ + YF + A ++ G RA +G ++D DDE R IE+ +
Sbjct: 113 MLRGGTTCANENYFFPDVQAAIYKQHGFRALVGAVIIDFPTAWANSDDEYFARAIELHDQ 172
Query: 163 EKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKII 222
+ + + APHAPYT S V + + + LV +H ET EI
Sbjct: 173 WR--------GDALIGTAFAPHAPYTVSDANFERVRVLADQLDVLVHLHTHETAQEIADS 224
Query: 223 REKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVF 282
+ +G+ P+ L+ + L+N++LIA H L++ +I+ ++ G ++ HCP SN+KL SG
Sbjct: 225 IKHHGQRPLARLDRLDLVNDRLIAVHMTQLTESEIQLCATRGVSVVHCPESNLKLASGFC 284
Query: 283 PMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLN 342
P VN+A+GTDG ASNN LD+L E R+A++L K + DP+ + + R ATL
Sbjct: 285 PAFALHRAGVNLAIGTDGCASNNDLDMLSENRIAAMLAKAVANDPTALDAATTLRAATLG 344
Query: 343 GAKALGL--KAGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEI 400
GA+ALG G I G AD+ +DL P+ L+ ++++A V + + G+
Sbjct: 345 GARALGFGHLIGSIEIGKQADLICVDLSALETQPLYHVLSQLVYAAGRQHVTDVWIAGQP 404
Query: 401 VMLDSELLTVDEEKVIDK 418
++ EL+ +D ++ K
Sbjct: 405 KLIQRELIDIDTAALVAK 422
>emb|CAC12188.1| (AL445066) chlorohydrolase related protein [Thermoplasma
acidophilum]
Length = 396
Score = 203 bits (512), Expect = 2e-51
Identities = 121/389 (31%), Positives = 216/389 (55%), Gaps = 11/389 (2%)
Query: 29 EGDKIVEVKRNINKPA-DEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEY 87
EGD I V +PA DE++D + +V+P FIN H H M +GL +DV L +L +
Sbjct: 4 EGDTITYV--GTGRPASDEIIDATGKVVMPGFINTHAHVGMSASKGLFDDVDLERFL-DM 60
Query: 88 IWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVGLRAYLGYGMV 147
+ + + + ++ ++L + EM +SG ++FVD+Y+ IA+A E+VG+RA+L + +
Sbjct: 61 TFKYDSQRTEEGIFNSARLGMYEMINSGITSFVDLYYSENVIARAAEQVGIRAFLSWVTL 120
Query: 148 DLDDEEKRKIEMRETEKLYEFIKKLDSSK-VNFILAPHAPYTCSFDCLRWVSEKSREWNS 206
D + ++ + E FI+ + + V + Y S + + E + +++
Sbjct: 121 DREFTTQKGDPLDNAEN---FIRSHQNMRFVKPSVGVQGIYVASDETYQRAKEIAERYDT 177
Query: 207 LVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGAT 266
++ +HL+ET+ E+ +K G+ P++ L+ +G+L+ ++IAAH +W + + + + G
Sbjct: 178 IMHMHLSETRKEVYDSVKKIGERPIEHLDKIGVLSSRVIAAHCVWATYHEAKLLGKNGVN 237
Query: 267 IAHCPASNMKLGSG-VFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHR 325
++ SN KL +G V P+ + L+ VN+ +GTD SNN+L+ M+ ++L K
Sbjct: 238 VSWNAVSNFKLATGGVPPVPEMLDAGVNITIGTDSNGSNNSLNFFEAMKFSALTVKNARW 297
Query: 326 DPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPV--NSPLASII 383
D SI+KS+ I AT++ AKAL L AG I G ADI ++D R+ L+P N+ + +I+
Sbjct: 298 DASIIKSQQILDFATIDAAKALRLNAGSIEVGKKADIVILDARRPELIPTDKNNVVNNIV 357
Query: 384 FSARGGDVDTLIVGGEIVMLDSELLTVDE 412
+S VD++I+ G L+ DE
Sbjct: 358 YSTNPASVDSVIIDGVFRKKGGRLIGFDE 386
>sp|O31352|YOR3_BACCE HYPOTHETICAL PROTEIN (ORF3) >gi|11356509|pir||T44621 hypothetical
protein 3 [imported] - Bacillus cereus (fragment)
>gi|2462117|emb|CAA72025.1| (Y11139) homology to
Escherichia coli ORF_o439 [Bacillus cereus]
Length = 312
Score = 195 bits (490), Expect = 9e-49
Identities = 103/287 (35%), Positives = 164/287 (56%), Gaps = 9/287 (3%)
Query: 45 DEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGS 104
DEV+D+ V+P +N HTH M +LRG+ +D+ L WL+ IWP+E + + +
Sbjct: 9 DEVIDMKGKWVLPGLVNTHTHVVMSLLRGIGDDMLLQPWLETRIWPLESQFTPELAVAST 68
Query: 105 KLALIEMAHSGTSTFVDMY----FHMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMR 160
+L L+EM SGT++F DM+ + I + G+RA + + ++ K +
Sbjct: 69 ELGLLEMVKSGTTSFSDMFNPIGVDQDAIMETVSRSGMRAAVSRTLFSFGTKDDEKKAIE 128
Query: 161 ETEKLYEFIKKL--DSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDE 218
E EK ++K+ +S + ++APH+PYTCS + L + + E ++V IHL+ET+ E
Sbjct: 129 EAEK---YVKRYYNESGMLTTMVAPHSPYTCSTELLEECARIAVENQTMVHIHLSETERE 185
Query: 219 IKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLG 278
++ I +YGK PV+ GL + AHG+ L++ + ++ +AH P SN+KLG
Sbjct: 186 VRDIEAQYGKRPVEYAASCGLFKRPTVIAHGVVLNENERAFLAEHDVRVAHNPNSNLKLG 245
Query: 279 SGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHR 325
SG+ +K LE + V + TD ASNN LD+ EMR+A+LLQKV R
Sbjct: 246 SGIANVKAMLEAGMKVGIATDSVASNNNLDMFEEMRIATLLQKVFIR 292
>sp|P72156|ATZA_PSESD ATRAZINE CHLOROHYDROLASE >gi|11352844|pir||T47197 atrazine
chlorohydrolase [validated] - Pseudomonas sp
>gi|3766246|gb|AAC64663.1| (U55933) atrazine
chlorohydrolase [Pseudomonas sp. ADP]
Length = 474
Score = 181 bits (454), Expect = 2e-44
Identities = 122/414 (29%), Positives = 210/414 (50%), Gaps = 36/414 (8%)
Query: 39 NINKPADEVLDVSKSLVIPSFINAHTHSPMVILRG-LAEDVPLMEWLQEYIWPVERKLRR 97
++ PAD V+D +V+P FINAHTH ++LRG + +WL ++P ++ +R
Sbjct: 42 SVPPPADRVIDARGKVVLPGFINAHTHVNQILLRGGPSHGRQFYDWLFNVVYPGQKAMRP 101
Query: 98 KDVYWGSKLALIEMAHSGTSTFVD-----MYFHMEEIAKATE-EVGLRAYLG-------- 143
+DV +L E SG +T + +Y E A A EVG+R
Sbjct: 102 EDVAVAVRLYCAEAVRSGITTINENADSAIYPGNIEAAMAVYGEVGVRVVYARMFFDRMD 161
Query: 144 ---YGMVDLDDEEKRKIE----MRETEKLYEFIKKLDSS-------KVNFILAPHAPYTC 189
G VD ++E M ET + I L +++ AP
Sbjct: 162 GRIQGYVDALKARSPQVELCSIMEETAVAKDRITALSDQYHGTAGGRISVWPAPATTTAV 221
Query: 190 SFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHG 249
+ + +RW +R+ + T+H+AE+ + +I +G SP + +E GLL+E+L AH
Sbjct: 222 TVEGMRWAQAFARDRAVMWTLHMAESDHDERI----HGMSPAEYMECYGLLDERLQVAHC 277
Query: 250 IWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDI 309
++ +D+R + +A SN LGSGV P+ + +E + V +GTD SN+++++
Sbjct: 278 VYFDRKDVRLLHRHNVKVASQVVSNAYLGSGVAPVPEMVERGMAVGIGTDNGNSNDSVNM 337
Query: 310 LREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGL--KAGVIAEGYLADIAVIDL 367
+ +M+ + + + +HRD ++ E I MAT++GA++LG+ + G I G AD+ ++DL
Sbjct: 338 IGDMKFMAHIHRAVHRDADVLTPEKILEMATIDGARSLGMDHEIGSIETGKRADLILLDL 397
Query: 368 RKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDEEKVIDKFLE 421
R P + A+I+F A G +VDT+++ G +VM + L + E+ + FLE
Sbjct: 398 RHPQTTPHHHLAATIVFQAYGNEVDTVLIDGNVVMENRRLSFLPPEREL-AFLE 450
>pir||F83627 hypothetical protein PA0142 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9945972|gb|AAG03532.1|AE004452_4
(AE004452) hypothetical protein [Pseudomonas aeruginosa]
Length = 449
Score = 164 bits (410), Expect = 2e-39
Identities = 123/429 (28%), Positives = 216/429 (49%), Gaps = 28/429 (6%)
Query: 8 LRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNINKPADEV---LDVSKSLVIPSFINAHT 64
+R L ++ + +++E +IVE+ +PA D S+ +V+P +N H
Sbjct: 6 IRNPLAIFTANGLDAAGGLVVEDGRIVELLGAGQQPAQPCASQFDASRHVVLPGLVNTHH 65
Query: 65 HSPMVILRGLAEDV--PLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDM 122
H + R A V PL WL+ ++PV +L + + +K+AL E+ SG +T D
Sbjct: 66 HFYQTLTRAWAPVVNQPLFPWLKT-LYPVWARLTPEKLELATKVALAELLLSGCTTAADH 124
Query: 123 YF--------HMEEIAKATEEVGLRAYLGYGMVDLDDEE-----KRKIEMRET-----EK 164
++ ++ A EE+G+RA L G + L +++ ++ ++ ET E+
Sbjct: 125 HYLFPGGLEQAIDVQAGVVEELGMRAMLTRGSMSLGEKDGGLPPQQTVQEAETILADSER 184
Query: 165 LY-EFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIR 223
L + ++ D ++V LAP +P++ + + +R +E + + + HLAET DE
Sbjct: 185 LIARYHQRGDGARVQIALAPCSPFSVTPEIMRASAEVAARHDVRLHTHLAETLDEEDFCL 244
Query: 224 EKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFP 283
+++G VD L+ VG L + AHGI + E+IR++ AG I HCP+SNM+L SG+ P
Sbjct: 245 QRFGLRTVDYLDSVGWLGPRTWLAHGIHFNAEEIRRLGEAGTGICHCPSSNMRLASGICP 304
Query: 284 MKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNG 343
+ + LG DG+ASN+ +++ E R A LQ++ + I E AT
Sbjct: 305 TVELEAAGAPIGLGVDGSASNDASNMILEARQALYLQRLRYGAERIT-PELALGWATRGS 363
Query: 344 AKALGLK-AGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVM 402
A+ LG G +A G AD+A+ L + + PL++++ A D ++VGG +
Sbjct: 364 ARLLGRSDIGELAPGKQADLALFKLDELRFSGSHDPLSALLLCA-ADRADRVMVGGAWRV 422
Query: 403 LDSELLTVD 411
+D + +D
Sbjct: 423 VDGAVEGLD 431
>gi|6753960 guanine deaminase [Mus musculus] >gi|9910725|sp|Q9R111|GUAD_MOUSE
GUANINE DEAMINASE (GUANASE) (GUANINE AMINASE) (GUANINE
AMINOHYDROLASE) (GAH)
>gi|5738216|gb|AAD50297.1|AF174583_1 (AF174583) guanine
deaminase [Mus musculus]
Length = 454
Score = 152 bits (379), Expect = 1e-35
Identities = 95/317 (29%), Positives = 174/317 (53%), Gaps = 24/317 (7%)
Query: 56 IPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMA-HS 114
+P ++ H H+P G D+PL+EWL +Y +P E++ R DV ++ +
Sbjct: 75 MPGLVDTHIHAPQYAFAGSNVDLPLLEWLNKYTFPTEQRFRSTDVAEEVYTRVVRRTLKN 134
Query: 115 GTSTFVDMYF---HMEE---IAKATEEVGLRAYLGYGMVDLDD-----EEKRKIEMRETE 163
GT+T YF H + +A+ T++ G RA++G +DL+D +E + ++ETE
Sbjct: 135 GTTTAC--YFGTIHTDSSLILAEITDKFGQRAFVGKVCMDLNDTVPEYKETTEESVKETE 192
Query: 164 KLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIR 223
+ + + + +V I+ P +C+ + + ++ + + H++E ++EI+ ++
Sbjct: 193 RFVSEMLQKNYPRVKPIVTPRFTLSCTETLMSELGNIAKTHDLYIQSHISENREEIEAVK 252
Query: 224 EKYG--KSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGV 281
Y K+ DV + LL K + AHG +LS+E++ S GA+IAHCP SN+ L SG+
Sbjct: 253 SLYPSYKNYTDVYDKNNLLTNKTVMAHGCYLSEEELNIFSERGASIAHCPNSNLSLSSGL 312
Query: 282 FPMKKALENNVNVALGTD--GAASNNTLDILREMRLAS---LLQKVIHRDPSIVKSEDIF 336
+ + L++ V + LGTD G S + LD +R + S L+ KV ++ ++ +++F
Sbjct: 313 LNVLEVLKHKVKIGLGTDVAGGYSYSMLDAIRRAVMVSNVLLINKVNEKNLTL---KEVF 369
Query: 337 RMATLNGAKALGLKAGV 353
R+ATL G++ALGL + +
Sbjct: 370 RLATLGGSQALGLDSEI 386
>emb|CAB61315.1| (AL132997) putative hydrolase [Streptomyces coelicolor A3(2)]
Length = 465
Score = 149 bits (373), Expect = 5e-35
Identities = 106/389 (27%), Positives = 179/389 (45%), Gaps = 23/389 (5%)
Query: 48 LDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLA 107
+D + L P +N H H + RGLA D L +WL ++P ++ + ++ +
Sbjct: 61 IDATGHLATPGLVNTHHHFYQWLTRGLATDHNLFDWLVA-LYPTWARIDEPMAHAAAQGS 119
Query: 108 LIEMAHSGTSTFVDM-YFHME-------EIAKATEEVGLRAYLGYGMVDLDDEEKRKIEM 159
L MA G +T D Y H I +A ++G+R L G +D + +
Sbjct: 120 LAMMARGGVTTAADHHYIHPRGAGDLSGAIVRAARDLGVRFTLARGSMDRGESDGGLPPD 179
Query: 160 RETEKLYEFIKKLDSS-----------KVNFILAPHAPYTCSFDCLRWVSEKSREWNSLV 208
E L + + +++ +AP +P++ S + +R +E +R +
Sbjct: 180 FAVESLDDALAATEATVREHHDPSFDAMTRVAVAPCSPFSVSTELMRQGAELARRLGVRL 239
Query: 209 TIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIA 268
H +ET +E K E +G P D E G L E + AH + ++D DI + G +A
Sbjct: 240 HTHGSETVEEEKFCHELFGMGPTDYFESTGWLGEDVWMAHCVHMNDSDIAAFARTGTGVA 299
Query: 269 HCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPS 328
HCP+SN +L +G+ + L V V LG DG ASN + ++ E+R A L+ ++ +
Sbjct: 300 HCPSSNARLAAGIARVPDLLAAGVPVGLGVDGTASNESGELHTELRNALLINRLGAHREA 359
Query: 329 IVKSEDIFRMATLNGAKALGLKA--GVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSA 386
+ + R+ T GA+ LG A G + G LAD+ + + + P+A+++ A
Sbjct: 360 ALNARGALRLGTYGGAQVLGRAAETGSLEPGKLADLVLWRMDTLAHSSIADPVAALVLGA 419
Query: 387 RGGDVDTLIVGGEIVMLDSELLTVDEEKV 415
V V G ++ D LLTVDE+ V
Sbjct: 420 -PAPVTASFVNGRQIVEDGRLLTVDEDAV 447
>sp|Q9WTT6|GUAD_RAT GUANINE DEAMINASE (GUANASE) (GUANINE AMINASE) (GUANINE
AMINOHYDROLASE) (GAH) >gi|4731644|gb|AAD15629.2|
(AF026472) guanine aminohydrolase [Rattus norvegicus]
Length = 454
Score = 148 bits (370), Expect = 1e-34
Identities = 90/310 (29%), Positives = 168/310 (54%), Gaps = 18/310 (5%)
Query: 56 IPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMA-HS 114
+P ++ H H+P G D+PL++WL +Y +P E++ + DV ++ +
Sbjct: 75 MPGLVDTHIHAPQYAFAGSNVDLPLLDWLNKYTFPTEKRFQSTDVAEEVYTRVVRRTLKN 134
Query: 115 GTSTFVDMYF---HMEE---IAKATEEVGLRAYLGYGMVDLDD-----EEKRKIEMRETE 163
GT+T YF H + +A+ T++ G RA++G +DL++ +E + ++ETE
Sbjct: 135 GTTTAC--YFGTIHTDSSLILAEITDKFGQRAFVGKVCMDLNNTVPEYKETTEESVKETE 192
Query: 164 KLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIR 223
+ + + + S+V I+ P +C+ + + ++ + + H++E ++EI+ ++
Sbjct: 193 RFVSEMLQKNYSRVKPIVTPRFSLSCTETLMSELGNIAKTHDLYIQSHISENREEIEAVK 252
Query: 224 EKYG--KSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGV 281
Y K+ DV + LL K + AHG +LS+E++ S GA+IAHCP SN+ L SG+
Sbjct: 253 SLYPGYKNYTDVYDKNNLLTNKTVMAHGCYLSEEELNVFSERGASIAHCPNSNLSLSSGL 312
Query: 282 FPMKKALENNVNVALGTD--GAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMA 339
+ L++ V + LGTD G S + LD +R + S + + + + +++FR+A
Sbjct: 313 LNVLDVLKHKVKIGLGTDVAGGYSYSMLDAIRRAVMVSNVLLINKVNEKSLTLKEVFRLA 372
Query: 340 TLNGAKALGL 349
TL G++ALGL
Sbjct: 373 TLGGSQALGL 382
>gb|AAF63337.1|AF245172_1 (AF245172) guanine deaminase [Rattus norvegicus]
Length = 454
Score = 148 bits (370), Expect = 1e-34
Identities = 90/310 (29%), Positives = 168/310 (54%), Gaps = 18/310 (5%)
Query: 56 IPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMA-HS 114
+P ++ H H+P G D+PL++WL +Y +P E++ + DV ++ +
Sbjct: 75 MPGLVDTHIHAPQYAFAGSNVDLPLLDWLNKYTFPTEKRFQSTDVAEEVYTRVVRRTLKN 134
Query: 115 GTSTFVDMYF---HMEE---IAKATEEVGLRAYLGYGMVDLDD-----EEKRKIEMRETE 163
GT+T YF H + +A+ T++ G RA++G +DL++ +E + ++ETE
Sbjct: 135 GTTTAC--YFGTIHTDSSLILAEITDKFGQRAFVGKVCMDLNNTVPEYKETTEESVKETE 192
Query: 164 KLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIR 223
+ + + + S+V I+ P +C+ + + ++ + + H++E ++EI+ ++
Sbjct: 193 RFVSEMLQKNYSRVKPIVTPRFSLSCTETLMSELGNIAKTHDLYIQSHISENREEIEAVK 252
Query: 224 EKYG--KSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGV 281
Y K+ DV + LL K + AHG +LS+E++ S GA+IAHCP SN+ L SG+
Sbjct: 253 SLYPGYKNYTDVYDKNNLLTNKTVMAHGCYLSEEELNVFSERGASIAHCPNSNLSLSSGL 312
Query: 282 FPMKKALENNVNVALGTD--GAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMA 339
+ L++ V + LGTD G S + LD +R + S + + + + +++FR+A
Sbjct: 313 LNVLDVLKHKVKIGLGTDVAGGYSYSMLDAIRRAVMVSNVLLINKVNEKSLTLKEVFRLA 372
Query: 340 TLNGAKALGL 349
TL G++ALGL
Sbjct: 373 TLGGSQALGL 382
>gi|4758426 guanine deaminase; guanase [Homo sapiens]
>gi|9910736|sp|Q9Y2T3|GUAD_HUMAN GUANINE DEAMINASE
(GUANASE) (GUANINE AMINASE) (GUANINE AMINOHYDROLASE)
(GAH) (P51-NEDASIN) >gi|4588080|gb|AAD25978.1|AF095286_1
(AF095286) guanine deaminase GDA [Homo sapiens]
>gi|6469320|gb|AAF13301.1|AF019638_1 (AF019638) nedasin
s-form [Homo sapiens]
Length = 454
Score = 140 bits (349), Expect = 3e-32
Identities = 87/310 (28%), Positives = 162/310 (52%), Gaps = 18/310 (5%)
Query: 56 IPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKD----VYWGSKLALIEM 111
+P ++ H H+ G + D+PL+EWL +Y +P E + + D VY +++ +
Sbjct: 75 MPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVY--TRVVRRTL 132
Query: 112 AHSGTSTFVDMYFHMEE---IAKATEEVGLRAYLGYGMVDLDD-----EEKRKIEMRETE 163
+ T+ H + +A T++ G RA++G +DL+D +E + ++ETE
Sbjct: 133 KNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETE 192
Query: 164 KLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIR 223
+ + + + S+V I+ P +CS + + ++ + + H++E +DE++ ++
Sbjct: 193 RFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVK 252
Query: 224 EKYG--KSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGV 281
Y K+ V + LL K + AHG +LS E++ GA+IAHCP SN+ L SG
Sbjct: 253 NLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGF 312
Query: 282 FPMKKALENNVNVALGTD--GAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMA 339
+ + L++ V + LGTD G S + LD +R + S + + + + +++FR+A
Sbjct: 313 LNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLA 372
Query: 340 TLNGAKALGL 349
TL G++ALGL
Sbjct: 373 TLGGSQALGL 382
>dbj|BAA86572.1| (AB033084) KIAA1258 protein [Homo sapiens]
Length = 479
Score = 140 bits (349), Expect = 3e-32
Identities = 87/310 (28%), Positives = 162/310 (52%), Gaps = 18/310 (5%)
Query: 56 IPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKD----VYWGSKLALIEM 111
+P ++ H H+ G + D+PL+EWL +Y +P E + + D VY +++ +
Sbjct: 100 MPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVY--TRVVRRTL 157
Query: 112 AHSGTSTFVDMYFHMEE---IAKATEEVGLRAYLGYGMVDLDD-----EEKRKIEMRETE 163
+ T+ H + +A T++ G RA++G +DL+D +E + ++ETE
Sbjct: 158 KNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETE 217
Query: 164 KLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIR 223
+ + + + S+V I+ P +CS + + ++ + + H++E +DE++ ++
Sbjct: 218 RFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVK 277
Query: 224 EKYG--KSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGV 281
Y K+ V + LL K + AHG +LS E++ GA+IAHCP SN+ L SG
Sbjct: 278 NLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGF 337
Query: 282 FPMKKALENNVNVALGTD--GAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMA 339
+ + L++ V + LGTD G S + LD +R + S + + + + +++FR+A
Sbjct: 338 LNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLA 397
Query: 340 TLNGAKALGL 349
TL G++ALGL
Sbjct: 398 TLGGSQALGL 407
>sp|Q52725|TRZA_RHOCO S-TRIAZINE HYDROLASE (N-ETHYLAMMELINE CHLOROHYDROLASE)
>gi|11280296|pir||T46666 N-ethylammeline chlorohydrolase
[validated] - Rhodococcus corallinus
>gi|294671|gb|AAA90931.1| (L16534) N-ethylammeline
chlorohydrolase [Rhodococcus corallinus]
Length = 477
Score = 134 bits (335), Expect = 1e-30
Identities = 80/277 (28%), Positives = 145/277 (51%), Gaps = 9/277 (3%)
Query: 145 GMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREW 204
G V +D+ + + ++L + ++ AP P+ S ++ E +
Sbjct: 177 GAVRMDESASTDHVLADLDQLITRHDRTADGRIRVWPAPAIPFMVSEKGMKAAQEIAASR 236
Query: 205 NSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAG 264
T+H++E E ++ + + + L +G L+++L+AAH + + DIR
Sbjct: 237 TDGWTMHVSEDPIEARV----HSMNAPEYLHHLGCLDDRLLAAHCVHIDSRDIRLFRQHD 292
Query: 265 ATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIH 324
I+ P SN L +G+ P+ + L + V V +GTD A N++++++ +M++ +L+ + H
Sbjct: 293 VKISTQPVSNSYLAAGIAPVPEMLAHGVTVGIGTDDANCNDSVNLISDMKVLALIHRAAH 352
Query: 325 RDPSIVKSEDIFRMATLNGAKALGL--KAGVIAEGYLADIAVIDLRKAHLLPVNSPLASI 382
RD SI+ E I MAT++GA+ +G+ + G + G ADI +DLR A P + A+I
Sbjct: 353 RDASIITPEKIIEMATIDGARCIGMADQIGSLEAGKRADIITLDLRHAQTTPAHDLAATI 412
Query: 383 IFSARGGDVDTLIVGGEIVMLD---SELLTVDEEKVI 416
+F A G +V+ ++V G +VM D S L T EEK +
Sbjct: 413 VFQAYGNEVNDVLVNGSVVMRDRVLSFLPTPQEEKAL 449
>sp|O14057|GUAD_SCHPO PROBABLE GUANINE DEAMINASE (GUANASE) (GUANINE AMINASE) (GUANINE
AMINOHYDROLASE) (GAH) >gi|7491828|pir||T41047
hypothetical protein SPCC1672.03c - fission yeast
(Schizosaccharomyces pombe) >gi|3451304|emb|CAA20441.1|
(AL031324) hypothetical protein [Schizosaccharomyces
pombe]
Length = 527
Score = 134 bits (335), Expect = 1e-30
Identities = 95/332 (28%), Positives = 162/332 (48%), Gaps = 19/332 (5%)
Query: 55 VIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHS 114
+ P I+ H H+P G+ DVPL++WL++Y +P+E L + ++E S
Sbjct: 71 MFPGLIDTHIHAPQYPNSGIGIDVPLLQWLEKYTFPLESSLADLEEARQVYKRVVERTLS 130
Query: 115 GTSTFVDMYFHMEE-----IAKATEEVGLRAYLGY-GMVDLDD----EEKRKIEMRETEK 164
+TF + + +A+ G RAY+G M +L E+ + + T +
Sbjct: 131 NGTTFASYFSTLHTPTSALLAEICYSYGQRAYIGKCNMNNLSPDHYCEKSAESSLEATRQ 190
Query: 165 LYEFIKKLDSSK--VNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKII 222
L ++ LD + V I+ P +C+ D L E + + N + H++E EI+++
Sbjct: 191 LISYMSILDPKREMVTPIITPRFAPSCTEDLLSGCGELAEKHNLPIQTHISENTSEIELV 250
Query: 223 REKYG--KSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSG 280
+E + KS DV + LL + I AH I L DE+I ++ + I+HCP SN L SG
Sbjct: 251 KELFPERKSYADVYDYYKLLTPQTILAHAIHLEDEEIELLTKRSSGISHCPTSNSILASG 310
Query: 281 VFPMKKALENNVNVALGTD--GAASNNTLDILREMRLASLLQKVIHRDPSIVKS-EDIFR 337
+ ++K L++ +NV LGTD G + + L LR + S + DP ++ ++
Sbjct: 311 LANVRKLLDSGINVGLGTDVSGGYAPSILIALRHAAMTSRSLSYVLGDPKVMLDLSELLY 370
Query: 338 MATLNGAKAL--GLKAGVIAEGYLADIAVIDL 367
+AT GA+ + G + G A G D ++DL
Sbjct: 371 LATQGGAEVVSRGDQVGSFAVGKYWDALIVDL 402
>gb|AAF52167.1| (AE003607) CG18143 gene product [Drosophila melanogaster]
Length = 448
Score = 133 bits (331), Expect = 4e-30
Identities = 96/379 (25%), Positives = 175/379 (45%), Gaps = 37/379 (9%)
Query: 55 VIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRR----KDVYWGSKLALIE 110
++P F++ H H+P GL D+PL++WL Y +P+E K + VY G A +
Sbjct: 66 LMPGFVDCHIHAPQFAQLGLGLDMPLLDWLNTYTFPLEAKFSNHQYAQQVYQGVVEATLR 125
Query: 111 MAHSGTSTFVDMYFHMEE---IAKATEEVGLRAYLGYGMVDLDDEE----KRKIEMRETE 163
+ S F H+E +A+ G RA +G + + E + + T
Sbjct: 126 CGTTLASYFATN--HLESTLTLAREAVRQGQRALIGKVCSNCNSPEFYVETAEESVSATL 183
Query: 164 KLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIR 223
E ++KL S V + P +CS + L+ + + ++ ++ + H++E +EI++++
Sbjct: 184 AFVEGVRKLGSPMVMPTITPRFALSCSKELLKSLGDIAKRFDLHIQSHISENLEEIEMVK 243
Query: 224 EKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFP 283
+ S ++ GLL K + AHG+ L D+++ + G ++AHCP SN L SG+
Sbjct: 244 GIFKTSYAGAYDEAGLLTNKTVLAHGVHLEDDEVALLKVRGCSVAHCPTSNTMLSSGLCD 303
Query: 284 MKKALENNVNVALGTDGAASNNT------LDILREMRLASLLQKVIHRDPSIVKSEDI-- 335
+++ + V+V LGTD + N+ L L + +K R + K++D
Sbjct: 304 VQRLVSGGVSVGLGTDVSGGNSVSIQDVLLRALDVSKHLDFFKKQNIRGTGVSKTQDFNY 363
Query: 336 --------FRMATLNGAKALGL-------KAGVIAEGYLADIAVIDLRKAHLLPVNSPLA 380
+ATL GAKAL L G + L D++V+D + L V+ +
Sbjct: 364 HQLKYKQALYLATLGGAKALSLDHLTGNFALGKDFDALLVDVSVVD-KPLRRLSVDELVE 422
Query: 381 SIIFSARGGDVDTLIVGGE 399
I++ ++ + V G+
Sbjct: 423 KFIYTGSDRNIVEVFVAGK 441
>gb|AAC15070.1| (AF060075) SdeB [Myxococcus xanthus]
Length = 462
Score = 130 bits (323), Expect = 4e-29
Identities = 108/403 (26%), Positives = 191/403 (46%), Gaps = 51/403 (12%)
Query: 55 VIPSFINAHTHSPMVILRGLAEDVP-------LMEWLQEYIWPVERKLRRKDVYWGSKLA 107
++P +N H+H+ ++RG E V W +E ++ L +D+Y S+ A
Sbjct: 52 LLPGLVNGHSHAFQRLIRGRTEYVASGREADDFWSW-REAMYRAAESLSPEDLYVASRQA 110
Query: 108 LIEMAHSGTSTFVDMYF--HMEE-------------IAKATEEVGLRAYL--------GY 144
+EMA +G +T + ++ H + + +A +VGLR L G+
Sbjct: 111 FVEMALAGITTVGEFHYVHHQSDGTPYADRNTLAHAVIRAARDVGLRICLLRVGYARAGF 170
Query: 145 GMVDLDDEEKRKIE------MRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVS 198
G V + ++R I+ + E L ++ + V+ LAPH+ + L ++
Sbjct: 171 G-VAANPRQRRFIDPDVETFLGSVEALAREVRA--DAAVSVGLAPHSVRAVPREWLAALA 227
Query: 199 EKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIR 258
S + V +H+AE EI+ ++G+ PV++L D+GLL A HG+ L+DE++
Sbjct: 228 SASVR-SLPVHMHVAEQPKEIEACLAEHGRRPVELLADLGLLGPGFTAVHGVHLTDEEVS 286
Query: 259 KISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILRE----MR 314
+ A AT+ CP++ LG G+ P + ++LG+D A+ + LD R+ +R
Sbjct: 287 LLGRAEATVCACPSTERNLGDGIVPADALVTAGARISLGSDSQATVDLLDEARQLEGHLR 346
Query: 315 LASLLQKVIHRDPSIVK--SEDIFRMATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHL 372
L+ L + V+ + + + MAT++GA++LGL G + G AD +DL L
Sbjct: 347 LSRLRRAVLDPGGGAMDGLAARLLDMATVDGARSLGLATGALEAGAPADFFTVDLHHPSL 406
Query: 373 ---LPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSELLTVDE 412
LP S L +I+ A V ++VGG V+ + +E
Sbjct: 407 VGALPA-SLLPAIVLGAEKAAVRDVVVGGREVVREGRHALAEE 448
>gb|AAG23552.1|AF244603_1 (AF244603) N-ethylanimeline chlorohydrolase [Carboxydothermus
hydrogenoformans]
Length = 138
Score = 122 bits (302), Expect = 1e-26
Identities = 59/129 (45%), Positives = 81/129 (62%), Gaps = 1/129 (0%)
Query: 56 IPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSG 115
+ IN HTH M + RG ++D+PLM+WL IWP E +L +DVYWGS L ++EM SG
Sbjct: 1 LTGLINGHTHVAMTLFRGASDDLPLMDWLNNVIWPSESRLTGEDVYWGSLLGIVEMIKSG 60
Query: 116 TSTFVDMYFHMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSS 175
T+TF DMYF M+E+A A E+ G+RA L GMV LD E K ++E+ E + +
Sbjct: 61 TTTFCDMYFFMDEVAHAVEQSGIRAILSRGMVALDPENGEK-GLKESIDFIEKWQGKANG 119
Query: 176 KVNFILAPH 184
++ LAPH
Sbjct: 120 RITTDLAPH 128
>sp|P76641|YGFP_ECOLI HYPOTHETICAL 50.2 KD PROTEIN IN KDUI-LYSS INTERGENIC REGION
>gi|7466471|pir||C65072 hypothetical protein b2883 -
Escherichia coli (strain K-12)
>gi|1789249|gb|AAC75921.1| (AE000372) orf, hypothetical
protein [Escherichia coli K12]
Length = 439
Score = 116 bits (288), Expect = 5e-25
Identities = 101/369 (27%), Positives = 176/369 (47%), Gaps = 38/369 (10%)
Query: 47 VLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKL 106
V D L++P F++ H H P + G A L+EWL ++ +P ER R +D+ + ++
Sbjct: 66 VRDYRGKLIVPGFVDTHIHYPQSEMVG-AYGEQLLEWLNKHTFPTER--RYEDLEYAREM 122
Query: 107 ALI---EMAHSGTST-FVDMYFH---MEEIAKATEEVGLRAYLGYGMVD-------LDDE 152
+ ++ +GT+T V H ++ + +A + +R G M+D LD
Sbjct: 123 SAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINMRMIAGKVMMDRNAPDYLLDTA 182
Query: 153 EKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREW-NSLVTIH 211
E ++++L E K + ++ + + P T S + + E+ ++ V H
Sbjct: 183 ES---SYHQSKELIERWHK--NGRLLYAITPRFAPTSSPEQMAMAQRLKEEYPDTWVHTH 237
Query: 212 LAETQDEIKIIREKYGKSP--VDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAH 269
L E +DEI ++ Y +DV GL + + AH + L +++ ++S ++IA
Sbjct: 238 LCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHCVHLEEKEWDRLSETKSSIAF 297
Query: 270 CPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSI 329
CP SN+ LGSG+F +KKA + V V +GTD + T ++L+ + A KV+
Sbjct: 298 CPTSNLYLGSGLFNLKKAWQKKVKVGMGTD-IGAGTTFNMLQTLNEA---YKVLQLQGYR 353
Query: 330 VKSEDIFRMATLNGAKALGLK--AGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSAR 387
+ + + F +ATL GAK+LGL G G AD V++ P +PL + +
Sbjct: 354 LSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVME-------PTATPLQQLRYDNS 406
Query: 388 GGDVDTLIV 396
VD L V
Sbjct: 407 VSLVDKLFV 415
>sp|Q9RYX4|GUAD_DEIRA PROBABLE GUANINE DEAMINASE (GUANASE) (GUANINE AMINASE) (GUANINE
AMINOHYDROLASE) (GAH) >gi|7471634|pir||F75614 conserved
hypothetical protein - Deinococcus radiodurans (strain
R1) >gi|6460486|gb|AAF12192.1|AE001862_18 (AE001862)
conserved hypothetical protein [Deinococcus radiodurans]
Length = 439
Score = 116 bits (288), Expect = 5e-25
Identities = 106/386 (27%), Positives = 176/386 (45%), Gaps = 36/386 (9%)
Query: 43 PADEVLDVSKSLVIPSFINAHTHSPMV-ILRGLAEDVPLMEWLQEYIWPVERKLRRKDVY 101
P EV D+ +++P FI+ H H P V +L GL + L+EWL P E +L D
Sbjct: 56 PDAEVHDLRGGVLLPGFIDTHVHYPQVRVLGGLG--MALLEWLDRNTLPEEARLA--DAA 111
Query: 102 WGSKLA---LIEMAHSGTSTFVDMYFH----MEEIAKATEEVGLRAYLGYGMVDLDDEEK 154
+ +A L +A GT+T + H M+E GLR G + D
Sbjct: 112 YARTIAGEFLHGLASHGTTTALVFGSHFAGAMDEFFAEAAARGLRVVAGQVVSD----RL 167
Query: 155 RKIEMRET-EKLYEFIKKL-----DSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSL- 207
+ E+ T E+ Y K L + + + P + S L + E+ +
Sbjct: 168 LRPELHTTPERAYAEGKALIERWHGQGRSLYAVTPRFSLSASEGILDACAALLTEFPDVR 227
Query: 208 VTIHLAETQDEIKIIREKY--GKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGA 265
T H+ E EI+++R + + +D E GL+ + + AH + ++ ++ +++
Sbjct: 228 FTSHINENNQEIEVVRGLFPGARDYLDTYERAGLVTPRSVFAHNVHPNERELGVLAAQRC 287
Query: 266 TIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHR 325
++AHCP SN LGSG+FP+++ L V+VALGTD +L+E A +Q+++
Sbjct: 288 SVAHCPCSNSALGSGLFPLRRHLAAGVHVALGTD-VGGGTGFSLLKEGLQAYFMQQLLGE 346
Query: 326 DPSIVKSEDIFRMATLNGAKALGL--KAGVIAEGYLADIAVIDLRK--------AHLLPV 375
+ + + + +ATL GA+ALGL + G G D + R AH
Sbjct: 347 EGAALSPAHLLYLATLAGAQALGLDGQVGDFTPGKQFDAVWLRPRAGSTLATVLAHAESE 406
Query: 376 NSPLASIIFSARGGDVDTLIVGGEIV 401
LA++ G DV+ + VGG +V
Sbjct: 407 ERTLAALFALGTGDDVERVWVGGGVV 432
>pir||G65071 hypothetical protein b2879 - Escherichia coli (strain K-12)
>gi|887829|gb|AAA83060.1| (U28375) D21141 uses 2nd
start; frame determined by Lac fusion [Escherichia coli]
>gi|1789244|gb|AAC75917.1| (AE000371) putative
proteoglycan [Escherichia coli K12]
Length = 464
Score = 116 bits (287), Expect = 6e-25
Identities = 104/408 (25%), Positives = 177/408 (42%), Gaps = 40/408 (9%)
Query: 25 DVLIEGDKIVEVKRNINK--PADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVP--- 79
D+ IE D IV + + + P ++ +V+P + +H H + RG+ ++
Sbjct: 44 DIAIENDVIVAIGDALTQRYPDASFKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCP 103
Query: 80 -LMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFH-------MEEIAK 131
+ L+ W ++R L + +Y+ + +E SG ++ +D + + +
Sbjct: 104 DFISTLKNLWWRLDRALDEESLYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRD 163
Query: 132 ATEEVGLRAYLGYGMVDLDDEEKRKIEMRE-TEKLYEFIKKLDSSK--------VNFILA 182
A +VGLRA + D ++ K E++E E+ F + +D +K V +
Sbjct: 164 AFLKVGLRAMTCFETTDRNNGIK---ELQEGVEENIRFARLIDEAKKATSEPYLVEAHIG 220
Query: 183 PHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNE 242
HAP+T L + E + + IH AE ++ YGK + L L++
Sbjct: 221 AHAPFTVPDAGLEMLREAVKATGRGLHIHAAEDLYDVSYSHHWYGKDLLARLAQFDLIDS 280
Query: 243 KLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAA 302
K + AHG++LS +DI ++ A + H SNM G L + N+ALGTDG
Sbjct: 281 KTLVAHGLYLSKDDITLLNQRDAFLVHNARSNMNNHVG---YNHHLSDIRNLALGTDGIG 337
Query: 303 SNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNG----AKALGLKAGVIAEGY 358
S D+ EM+ A HRD D F A NG ++ G K G++ GY
Sbjct: 338 S----DMFEEMKFAFFK----HRDAGGPLWPDSFAKALTNGNELMSRNFGAKFGLLEAGY 389
Query: 359 LADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSE 406
AD+ + D L ++ I F G V +++V G +V D +
Sbjct: 390 KADLTICDYNSPTPLLADNIAGHIAFGMGSGSVHSVMVNGVMVYEDRQ 437
>gb|AAA83064.1| (U28375) ORF_o439 [Escherichia coli]
Length = 439
Score = 116 bits (287), Expect = 6e-25
Identities = 101/369 (27%), Positives = 175/369 (47%), Gaps = 38/369 (10%)
Query: 47 VLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKL 106
V D L++P F++ H H P + G A L+EWL ++ +P ER R +D+ + ++
Sbjct: 66 VRDYRGKLIVPGFVDTHIHYPQSEMVG-AYGEQLLEWLNKHTFPTER--RYEDLEYAREM 122
Query: 107 ALI---EMAHSGTST-FVDMYFH---MEEIAKATEEVGLRAYLGYGMVD-------LDDE 152
+ ++ +GT+T V H ++ + +A + +R G M+D LD
Sbjct: 123 SAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINMRMIAGKVMMDRNAPDYLLDTA 182
Query: 153 EKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREW-NSLVTIH 211
E ++++L E K + ++ + + P T S + + E+ ++ V H
Sbjct: 183 ES---SYHQSKELIERWHK--NGRLLYAITPRFAPTSSPEQMAMAQRLKEEYPDTWVHTH 237
Query: 212 LAETQDEIKIIREKYGKSP--VDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAH 269
L E +DEI ++ Y +DV GL + + AH + L +++ ++S +IA
Sbjct: 238 LCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHCVHLEEKEWDRLSETKXSIAF 297
Query: 270 CPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSI 329
CP SN+ LGSG+F +KKA + V V +GTD + T ++L+ + A KV+
Sbjct: 298 CPTSNLYLGSGLFNLKKAWQKKVKVGMGTD-IGAGTTFNMLQTLNEA---YKVLQLQGYR 353
Query: 330 VKSEDIFRMATLNGAKALGLK--AGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSAR 387
+ + + F +ATL GAK+LGL G G AD V++ P +PL + +
Sbjct: 354 LSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVME-------PTATPLQQLRYDNS 406
Query: 388 GGDVDTLIV 396
VD L V
Sbjct: 407 VSLVDKLFV 415
>sp|Q46812|SSNA_ECOLI SSNA PROTEIN
Length = 442
Score = 116 bits (287), Expect = 6e-25
Identities = 104/408 (25%), Positives = 177/408 (42%), Gaps = 40/408 (9%)
Query: 25 DVLIEGDKIVEVKRNINK--PADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVP--- 79
D+ IE D IV + + + P ++ +V+P + +H H + RG+ ++
Sbjct: 22 DIAIENDVIVAIGDALTQRYPDASFKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCP 81
Query: 80 -LMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFH-------MEEIAK 131
+ L+ W ++R L + +Y+ + +E SG ++ +D + + +
Sbjct: 82 DFISTLKNLWWRLDRALDEESLYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRD 141
Query: 132 ATEEVGLRAYLGYGMVDLDDEEKRKIEMRE-TEKLYEFIKKLDSSK--------VNFILA 182
A +VGLRA + D ++ K E++E E+ F + +D +K V +
Sbjct: 142 AFLKVGLRAMTCFETTDRNNGIK---ELQEGVEENIRFARLIDEAKKATSEPYLVEAHIG 198
Query: 183 PHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNE 242
HAP+T L + E + + IH AE ++ YGK + L L++
Sbjct: 199 AHAPFTVPDAGLEMLREAVKATGRGLHIHAAEDLYDVSYSHHWYGKDLLARLAQFDLIDS 258
Query: 243 KLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAA 302
K + AHG++LS +DI ++ A + H SNM G L + N+ALGTDG
Sbjct: 259 KTLVAHGLYLSKDDITLLNQRDAFLVHNARSNMNNHVG---YNHHLSDIRNLALGTDGIG 315
Query: 303 SNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNG----AKALGLKAGVIAEGY 358
S D+ EM+ A HRD D F A NG ++ G K G++ GY
Sbjct: 316 S----DMFEEMKFAFFK----HRDAGGPLWPDSFAKALTNGNELMSRNFGAKFGLLEAGY 367
Query: 359 LADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLDSE 406
AD+ + D L ++ I F G V +++V G +V D +
Sbjct: 368 KADLTICDYNSPTPLLADNIAGHIAFGMGSGSVHSVMVNGVMVYEDRQ 415
>dbj|BAB03904.1| (AP001507) unknown conserved protein [Bacillus halodurans]
Length = 448
Score = 116 bits (287), Expect = 6e-25
Identities = 110/449 (24%), Positives = 202/449 (44%), Gaps = 44/449 (9%)
Query: 7 LLRGGLVLYGR-DYKLTRADVLIEGDKIVEVKRNINKPAD-EVLDVSKSLVIPSFINAHT 64
L++ GLVL + ++K D+LIEG I +++ NI D E++D +V+P F++ H
Sbjct: 5 LIKNGLVLDMKGNHKPQAKDILIEGKWIRDIRPNIEPEVDTEIIDAEGKIVMPGFVDTHR 64
Query: 65 HSPMVILRGLAEDVPLMEWLQE-YIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMY 123
H +LR + D L+ +L Y + L +D Y + +E +G +T +D
Sbjct: 65 HVWESLLRHIGTDWTLLTYLDNLYYGNLGSMLTPEDSYIANLWGALEAIDAGVTTVLDWS 124
Query: 124 F-----HMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMR---ETEKLYEFIKKLDSS 175
H + K + G+RA +G + R E+R + +++ + + D
Sbjct: 125 MLETPEHADASIKGLQAAGIRAVFAHGTPGYETYWSRDSEVRHPKDAKRVKKEYFQSDDQ 184
Query: 176 KVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYG-----KSP 230
+ LA P S++ + +RE +++ ++H+ +G
Sbjct: 185 LLTMALAIRGPEFSSWEVTLDDIQLARELDAIASMHIG------------FGTWGPHDRS 232
Query: 231 VDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALEN 290
+ + + GLL+ L H + + I+ +GA+++ P M +G G +P L
Sbjct: 233 ITRMREAGLLDSDLNLVHVNRIQPHEYEYIAESGASLSVTPEVEMMMGHG-YPATGYLHK 291
Query: 291 NVN-VALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVKSE----------DIFRMA 339
+ V LG D + D+ +M+ A ++ + + + E D+ A
Sbjct: 292 HRGLVTLGVDVVVA-TAGDMFAQMKFALQAERAWQNEQRLDRGEMPEQLKMTTNDVLTFA 350
Query: 340 TLNGAKALGL--KAGVIAEGYLADIAVIDLRKAHLLPVN-SPLASIIFSARGGDVDTLIV 396
TLNGAKAL L K G + G AD+ +I+ +L P+N P+ +++ SAR +VD++ +
Sbjct: 351 TLNGAKALKLDDKIGTLDVGKEADLLLINPSSFNLFPLNHEPVGAVVQSARPENVDSVFI 410
Query: 397 GGEIVMLDSELLTVDEEKVIDKFLEVSVA 425
G V +LL D + + +K L S A
Sbjct: 411 AGRPVKRHGKLLFDDLDGLRNKVLAASEA 439
>gi|6319963 Ydl238cp [Saccharomyces cerevisiae]
>gi|2833210|sp|Q07729|GUAD_YEAST PROBABLE GUANINE
DEAMINASE (GUANASE) (GUANINE AMINASE) (GUANINE
AMINOHYDROLASE) (GAH) >gi|2131372|pir||S67802
hypothetical protein YDL238c - yeast (Saccharomyces
cerevisiae) >gi|1431404|emb|CAA98818.1| (Z74286) ORF
YDL238c [Saccharomyces cerevisiae]
Length = 489
Score = 111 bits (274), Expect = 2e-23
Identities = 88/333 (26%), Positives = 162/333 (48%), Gaps = 18/333 (5%)
Query: 51 SKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIE 110
+ S P F++ H H G+ + L++WL++Y +P+E L +++ +I
Sbjct: 88 NNSFYFPGFVDTHNHVSQYPNVGVFGNSTLLDWLEKYTFPIEAALANENIAREVYNKVIS 147
Query: 111 MAHSGTSTFVDMYFHMEE-----IAKATEEVGLRAYLGYGMVDLDDEE----KRKIEMRE 161
S +T V Y ++ +A+ + +G R +G +D + E K
Sbjct: 148 KTLSHGTTTVAYYNTIDLKSTKLLAQLSSLLGQRVLVGKVCMDTNGPEYYIEDTKTSFES 207
Query: 162 TEKLYEFIKK-LDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIK 220
T K+ ++I++ + VN I+ P +CS + ++ +S+ ++ N V HL+E ++EI+
Sbjct: 208 TVKVVKYIRETICDPLVNPIVTPRFAPSCSRELMQQLSKLVKDENIHVQTHLSENKEEIQ 267
Query: 221 IIREKYGK--SPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLG 278
+++ + + S DV + GLL EK + AH I L+D + R I I+HCP SN L
Sbjct: 268 WVQDLFPECESYTDVYDKYGLLTEKTVLAHCIHLTDAEARVIKQRRCGISHCPISNSSLT 327
Query: 279 SGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVK---SEDI 335
SG ++ L+ + V LGTD +A ++ + + ++ + + R+ K SE +
Sbjct: 328 SGECRVRWLLDQGIKVGLGTDVSAGHSCSILTTGRQAFAVSRHLAMRETDHAKLSVSECL 387
Query: 336 FRMATLNGAKALGL--KAGVIAEGYLADIAVID 366
F +AT+ GA+ L + G G D +ID
Sbjct: 388 F-LATMGGAQVLRMDETLGTFDVGKQFDAQMID 419
>sp|P95442|ATZB_PSESD HYDROXYATRAZINE HYDROLASE >gi|1732206|gb|AAC45138.1| (U66917) AtzB
[Pseudomonas sp. ADP]
Length = 481
Score = 111 bits (274), Expect = 2e-23
Identities = 108/436 (24%), Positives = 181/436 (40%), Gaps = 40/436 (9%)
Query: 11 GLVLYGRDYKLTRADVLIEGDKIVEVKRNINKPAD---EVLDVSKSLVIPSFINAHTHSP 67
G VL G D + +++ G + I + EV++ P IN H H
Sbjct: 19 GTVLNGVDILVRDGEIIGLGPDLPRTLAPIGVGQEQGVEVVNCRGLTAYPGLINTHHHFF 78
Query: 68 MVILRGLAE----DVPLMEWLQEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMY 123
+R LA + ++ WL++ I+PV + +Y + +++ E+ G +T D
Sbjct: 79 QAFVRNLAPLDWTQLDVLAWLRK-IYPVFALVDEDCIYHSTVVSMAELIKHGCTTAFDHQ 137
Query: 124 FH---------MEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDS 174
++ ++ A +GLR + G G + L E I E F+ +
Sbjct: 138 YNYSRRGGPFLVDRQFDAANLLGLRFHAGRGCITLPMAEGSTIPDAMRESTDTFLADCER 197
Query: 175 SKVNF-----------ILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIR 223
F ++AP +P + + +R + HL E + + R
Sbjct: 198 LVSRFHDPRPFAMQRVVVAPSSPVIAYPETFVESARLARHLGVSLHTHLGEGETPAMVAR 257
Query: 224 EKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFP 283
+G+ +D E+ G + + AHG + DI ++++ G +AHCPA +G+ V
Sbjct: 258 --FGERSLDWCENRGFVGPDVWLAHGWEFTAADIARLAATGTGVAHCPAPVFLVGAEVTD 315
Query: 284 MKKALENNVNVALGTDGAASNNTLDILREMRLASLLQ--KVIHRDPSIVKSEDIFRMATL 341
+ V V G DG ASN++ ++ +RLA LLQ K R + D RMAT
Sbjct: 316 IPAMAAAGVRVGFGVDGHASNDSSNLAECIRLAYLLQCLKASERQHPVPAPYDFLRMATQ 375
Query: 342 NGAKALGL-KAGVIAEGYLADIAVIDLRKAHLLPVN----SPLASIIFSARGGDVDTLIV 396
GA L G +A G AD +DL + + N S A + FS G VD ++
Sbjct: 376 GGADCLNRPDLGALAVGRAADFFAVDLNRIEYIGANHDPRSLPAKVGFS---GPVDMTVI 432
Query: 397 GGEIVMLDSELLTVDE 412
G++V + E +DE
Sbjct: 433 NGKVVWRNGEFPGLDE 448
>pir||T49607 guanine deaminase (Gda) related protein [imported] - Neurospora
crassa >gi|7801011|emb|CAB91408.1| (AL355931) guanine
deaminase (Gda) related protein [Neurospora crassa]
Length = 424
Score = 109 bits (271), Expect = 4e-23
Identities = 91/344 (26%), Positives = 158/344 (45%), Gaps = 24/344 (6%)
Query: 55 VIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLR----RKDVYWGSKLALIE 110
+IP FI+ H H+P RGL + +++WL +P E + R + +Y + +
Sbjct: 44 IIPGFIDTHNHAPQWAQRGLGQGQHILDWLSAITFPNEGRFRDPSHAQRIYSSAIDGFLR 103
Query: 111 MAHSGTSTFVDMYFHMEEI-AKATEEVGLRAYLGY-----GMVDLDDEEKRKIEMRETEK 164
+ S + ++ I A G RA++G D + + +R+TE
Sbjct: 104 QGITTASYYGSIHPEATNILADLCLAKGQRAFVGKCNMTRNSPDYYRDASVEQSLRDTES 163
Query: 165 LYEFIKKLDSSKV--NFILAPHAPYTCSFDCLRWVSEKSREWNSL-VTIHLAETQDEIKI 221
I+K+D + +L P +C D L + + + + L + H E + EI
Sbjct: 164 CIAHIRKIDPEGMLLKHVLTPRFAISCDADGLAGLGQIAAKNPDLPIQTHFNEAEQEITA 223
Query: 222 IREKYGK--SPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGS 279
RE + + S D+ GLL ++ I AH +++ + K+ +AHCP SNM +G
Sbjct: 224 TRELFPQFSSEADLYHHYGLLTKRSILAHCCYMAPHEFDKLKELQCGVAHCPISNMTVGG 283
Query: 280 GVF--PMKKALENNVNVALGTD--GAASNNTLDILREMRLASLLQKVIH--RDPSIVKSE 333
G P+++ L + V LGTD G S++ LD +R+ +AS ++V RD + K
Sbjct: 284 GFMAAPIREFLNRGIKVGLGTDSGGGFSSSMLDAIRQAMIASHAREVESKGRDKGL-KIA 342
Query: 334 DIFRMATLNGAKALGL--KAGVIAEGYLADIAVIDLRKAHLLPV 375
+ F +ATL GA+ L K G G D V+D ++ ++ +
Sbjct: 343 EAFYLATLGGAEVCCLEDKVGNFEVGKEFDALVVDWQRDGVMTI 386
>pir||D83456 probable guanine deaminase PA1521 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947478|gb|AAG04910.1|AE004580_10 (AE004580)
probable guanine deaminase [Pseudomonas aeruginosa]
Length = 434
Score = 106 bits (263), Expect = 4e-22
Identities = 91/343 (26%), Positives = 164/343 (47%), Gaps = 23/343 (6%)
Query: 46 EVLDVSKSLVIPSFINAHTHSPMV-ILRGLAEDVPLMEWLQEYIWPVERKLR-RKDVYWG 103
EV + +L+ P FI+ H H P ++ E L++WL Y +P ER+ +
Sbjct: 60 EVFEYRDALITPGFIDTHIHFPQTGMIASYGEQ--LLDWLNTYTFPTERQFGDQAHADQV 117
Query: 104 SKLALIEMAHSGTST---FVDMYFH-MEEIAKATEEVGLRAYLGYGMVDLDDEE----KR 155
+++ L E+ +GT+T F ++ +E + +A + LR G M+D + +
Sbjct: 118 AEIFLQELLRNGTTTALVFGSVHRQSVESLFEAARRLDLRLIAGKVMMDRNAPDYLTDTA 177
Query: 156 KIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSL-VTIHLAE 214
+ R+++ L E + ++ + + P T + + L + RE + + HL+E
Sbjct: 178 ESSYRDSKALIE--RWHGQGRLLYAVTPRFAPTSTAEQLDMAARLLREHPGVYLHTHLSE 235
Query: 215 TQDEIKIIREKYGKSP--VDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPA 272
EI+ ++E + + +DV + GLL + + AHG+ L D + ++++ G+ +A CP
Sbjct: 236 NLKEIEWVKELFPERSGYLDVYDHHGLLGPRSVFAHGVHLCDGECQRLAETGSAVAFCPT 295
Query: 273 SNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVKS 332
SN+ LGSG+F + K V V LGTD A + +++ + KV+ + +
Sbjct: 296 SNLFLGSGLFDLPKLERYKVKVGLGTDVGAGTS----FSQLQSLNEAYKVMQLQGARLDP 351
Query: 333 EDIFRMATLNGAKALGL--KAGVIAEGYLADIAVIDLRKAHLL 373
+ATL GA+AL L + G A AD V+D LL
Sbjct: 352 FKSLYLATLGGARALELDDRIGSFATSNEADFVVLDYHATPLL 394
>pir||H83628 probable guanine deaminase PA0134 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9945963|gb|AAG03524.1|AE004451_5 (AE004451) probable
guanine deaminase [Pseudomonas aeruginosa]
Length = 456
Score = 96.7 bits (237), Expect = 4e-19
Identities = 87/340 (25%), Positives = 165/340 (47%), Gaps = 22/340 (6%)
Query: 43 PADEVLDVS-KSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVY 101
PAD L+ + L++P F++ H H P + + + L++WL+ + +P E++
Sbjct: 78 PADLPLEEHPQRLLLPGFVDCHVHYPQLGVIA-SYGTQLLDWLETHTFPAEQRFADAGYA 136
Query: 102 WG-SKLALIEMAHSGTSTFVDM----YFHMEEIAKATEEVGLRAYLGYGMVDLDDE---- 152
++L L E+ GT+T + E +A ++ LR G ++D +
Sbjct: 137 AAQAELFLDELLRHGTTTALVFGTVHAVSAEAFFQAAQKRRLRMIAGKVLMDRNAPPALC 196
Query: 153 EKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNSL-VTIH 211
+ E+ L E + + ++ + + P T S + L + E+ + + H
Sbjct: 197 DTAASGYAESRALIE--RWHGNGRLQYAVTPRFAPTSSPEQLAAAARLLDEYPGVYLHTH 254
Query: 212 LAETQDEIKIIREKYGKSP--VDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAH 269
L+E E+ + E + ++ +DV GL+ E+ + AHGI LS+ + R ++ A +AH
Sbjct: 255 LSENLKEVAWVGELFPQAQDYLDVYHRAGLVGERSVFAHGIHLSERECRCLAHKNAALAH 314
Query: 270 CPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSI 329
CP+SN+ +GSG+F + +A + + V +G+D +L +L + A +Q++ R S+
Sbjct: 315 CPSSNLFIGSGLFDLGRAQQYGIRVGIGSD-VGGGTSLSLLANLADAYKIQQL--RGTSL 371
Query: 330 VKSEDIFRMATLNGAKALGLK--AGVIAEGYLADIAVIDL 367
+ ++ +ATL GA+AL L G G AD +DL
Sbjct: 372 DPFQALY-LATLGGARALDLDGLVGNFLPGREADFVALDL 410
>sp|Q58110|Y699_METJA HYPOTHETICAL PROTEIN MJ0699 >gi|2128449|pir||C64387 hypothetical
protein MJ0699 - Methanococcus jannaschii
>gi|1591414|gb|AAB98692.1| (U67516) atrazine
chlorohydrolase isolog [Methanococcus jannaschii]
Length = 380
Score = 96.0 bits (235), Expect = 7e-19
Identities = 109/393 (27%), Positives = 169/393 (42%), Gaps = 35/393 (8%)
Query: 7 LLRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFINAHTHS 66
LL LYG D+KL + ++IE I N+ EV++ K LVIPS INAHTH
Sbjct: 5 LLLKSQFLYGEDFKLRKGTLIIEEGIIKGFTDEHNER--EVIEF-KGLVIPSLINAHTH- 60
Query: 67 PMVILRGLAEDVPLMEWLQEYIWPVERKLRR-------KDVYWGSKLALIEMAHSGTSTF 119
I +D+ + + L E + P R + G KL L +M G F
Sbjct: 61 ---IADNSIKDIGINKTLDELVKPPNGLKHRYLTECSDDLLAEGMKLGLGDMREHGIKYF 117
Query: 120 VDMYFHMEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNF 179
D + + L+ Y + L K++ E E++ + L S N
Sbjct: 118 CDFRENGVRGISLLNKA-LKCYDYPKAIILG--RPIKVDKDEIEEVLKVSNGLGLSGANE 174
Query: 180 ILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGL 239
F + EK + L IH AE + ++ KYG + V+ L D+ +
Sbjct: 175 FKDDELKLI--FKIFKKFKEKDDK--KLFAIHAAEHRGAVEYSLNKYGMTEVERLIDLKI 230
Query: 240 LNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTD 299
+ ++ HG L+D D+ + + C +N+ G+ P L +N+ V +GTD
Sbjct: 231 KPDFIV--HGTHLTDNDLELLKENNIPVVACVRANLSFNVGM-PKLNELNDNLLVGIGTD 287
Query: 300 GAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLK-AGVIAEGY 358
+N+ I +EM + K+ H +P +DI RMAT+N AK L L+ G++ EG+
Sbjct: 288 NFMANSP-SIFKEM---DFIYKLYHIEP-----KDILRMATINNAKILKLENVGLVDEGF 338
Query: 359 LADIAVIDLRKAHLLPVNSPLASIIFSARGGDV 391
A I A L N +AS++ GDV
Sbjct: 339 KAVFTFIKPTNAILFSKNI-IASVVTRCEKGDV 370
>emb|CAB89443.1| (AL354048) putative chlorohydrolase [Streptomyces coelicolor A3(2)]
Length = 449
Score = 93.6 bits (229), Expect = 4e-18
Identities = 97/408 (23%), Positives = 174/408 (41%), Gaps = 40/408 (9%)
Query: 28 IEGDKIVEVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWL-QE 86
+ +I V + + P + + L +P NAH+H+ LRG + W +E
Sbjct: 29 VRDGRITAVNQGVATPPPGA-GILRGLTLPGLANAHSHAFHRALRGTVQVGSGTFWTWRE 87
Query: 87 YIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYF--HM-------------EEIAK 131
++ V +L + ++ EMA +G + + ++ H E + +
Sbjct: 88 VMYSVADRLTPDTYHALARAVYAEMALAGITAVGEFHYVHHAPGGTPYADPNAMGEALIE 147
Query: 132 ATEEVGLR------AYLGYGMVDLDDEEKRKIEMRETEKLYE---FIKKLDSSKVNFILA 182
A E G+R YL G + + +R+ + E +K+ D +++ A
Sbjct: 148 AAAEAGVRITLLDTCYLSSGFGEPPNTHQRRFSDGTADAWAERCSVLKERDHARIG--AA 205
Query: 183 PHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDVGLLNE 242
H+ D L V++ + E + + +HL+E E R+ +G++P +L D G+L
Sbjct: 206 IHSVRAVPADQLATVAQWAEERRAPLHVHLSEQTAENDACRQAHGRTPTRLLADHGVLGA 265
Query: 243 KLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAA 302
+ H L+DEDI + + C + L G+ P ++LG+D
Sbjct: 266 RTTGVHNTHLTDEDIALLGGSRTGTCMCLTTERDLADGIGPAAALQRAGSPLSLGSD--- 322
Query: 303 SNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALG------LKAGVIAE 356
S+ +D+L E R L +++ R + + R AT +G ALG ++AG A+
Sbjct: 323 SHAVVDLLEEARAMELNERLRTRARGHWTAAALLRAATADGHAALGWDDTGRIEAGARAD 382
Query: 357 GYLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVMLD 404
LA IA+ +R A LP + +F+A DV +VGG V+ D
Sbjct: 383 --LATIALDSVRTAGPLP-RLGAETAVFAATAADVRHTVVGGRHVVRD 427
>sp|O27075|Y994_METTH HYPOTHETICAL PROTEIN MTH994 >gi|7482754|pir||B69233 N-ethylammeline
chlorohydrolase related protein - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622095|gb|AAB85491.1| (AE000872) N-ethylammeline
chlorohydrolase related protein [Methanobacterium
thermoautotrophicum]
Length = 384
Score = 87.8 bits (214), Expect = 2e-16
Identities = 97/404 (24%), Positives = 177/404 (43%), Gaps = 33/404 (8%)
Query: 6 VLLRGGLVLYGRDYKLTRADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFINAHTH 65
+++ G +L G + R +++IE D I++ + P+ E +D SK +V P+ +N+H H
Sbjct: 4 LVVENGTILRGPELTPQRKNLVIE-DGIIKEITDERAPSGERIDASKLMVCPALVNSHVH 62
Query: 66 SPMVILRGLAEDVPLMEWLQEYIWPVERKLRRKD---VYWGSKLALIEMAHSGTSTFVDM 122
+ + + PL + ++ R L + + + +M G +F+D
Sbjct: 63 IGDSVALDVGDGRPLEDIVRPPNGLKHRILESSPPGMLMEAMRNSARDMITHGIGSFIDY 122
Query: 123 YFH----MEEIAKATEEVGLRAY-LGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKV 177
+E + +A ++ + LG V D E R R + +V
Sbjct: 123 REGGPEGVELLREAIGDLPISGIILGRDPVVFDQEASRAEIRRRVRGVL---------RV 173
Query: 178 NFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDV 237
+ AP + + + E+ + +IH+AE ++ + E G S V+ +
Sbjct: 174 SDGFAPSGMGEITDETASIIVEECERAGKIASIHVAEHRESQRRSLEDTGMSEVERALNA 233
Query: 238 GLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALG 297
G KL+ H ED++ + +GA++ CP SN L SG+ P+++ E +N+ LG
Sbjct: 234 GF---KLLV-HLTNPVREDLKLVRESGASVVLCPRSNGALSSGIPPIRRMHELGINLLLG 289
Query: 298 TDGAASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEG 357
TD N+ D+LREM + + R ++ RMAT N + G GVI EG
Sbjct: 290 TDNLMFNSP-DMLREMEYTLKVTRGCAR--RYFPPVEVLRMATSNTSAFTG--TGVIEEG 344
Query: 358 YLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIV 401
+ AD+ +++ P SII ++ LI+ G++V
Sbjct: 345 FPADLILVEKLS------GDPYLSIINRTESKNIIYLIIKGKLV 382
>gb|AAC44523.1| (U38524) ORF1; Method: conceptual translation supplied by author
[Campylobacter jejuni]
Length = 518
Score = 87.8 bits (214), Expect = 2e-16
Identities = 103/422 (24%), Positives = 191/422 (44%), Gaps = 59/422 (13%)
Query: 12 LVLYGRDYKLTRADVLIEGDKIVEVKR--NINK--PADEVLDVSK-SLVIPSFINAHTHS 66
L L D+ + + DKI+E+ N+ K P +++ K S+++P+FIN HTH
Sbjct: 118 LFLCDEDFTILENQAFVFEDKILELGELDNLKKKYPKAKIIKTPKNSVILPAFINPHTHL 177
Query: 67 PMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALI-----EMAHSGTSTFVD 121
+ WL+ I R + +K LI +M SG T +
Sbjct: 178 EFSANSTTLHFGEFLIWLKSVI------NSRSILNAQAKEELILQSIKKMQKSGIGTIGE 231
Query: 122 MYFH---MEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSS--- 175
+ ++ KA+ + G+R ++ ++ + +K EF+K+ ++S
Sbjct: 232 ISSFGSDLDPCLKASHK-GMRIVFFNEILGTNENQVE-------DKKQEFLKRFENSLKF 283
Query: 176 KVNFILAP---HAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYG----- 227
K +F + H+PY+ + + +++ N L + H E++ E +RE G
Sbjct: 284 KNDFFIPAISIHSPYSTHPSLAYFALDLAKKQNLLASTHFLESKAENIWLRESKGGFKKW 343
Query: 228 -------KSPVDVLEDVGLLNE--KLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLG 278
P+ +D L + + + H ++L + + + +I HC SN L
Sbjct: 344 LENFTLHPKPLYTPKDFVKLFKGVRTLFTHCVYLKEYEW--LDKNLHSITHCAFSNRLLS 401
Query: 279 SGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVK-SEDIFR 337
+K AL++ +N+ LGTDG +SN +L +L EMR A+LL IH++ +++ + + +
Sbjct: 402 QKSLDLKTALKSGLNIHLGTDGLSSNISLSLLDEMR-ANLL---IHKNFDLLELASKLLQ 457
Query: 338 MATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVG 397
M TL A+AL L G + +G +AD +V +L + + A + F +VD L +
Sbjct: 458 MVTLYPARALNLNLGELKKGKIADFSVFELGEC-----DKKQAPLQFILNAKEVDKLFIK 512
Query: 398 GE 399
G+
Sbjct: 513 GK 514
>pir||G81422 hypothetical protein Cj0067 [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6967565|emb|CAB72554.1|
(AL139074) hypothetical protein Cj0067 [Campylobacter
jejuni]
Length = 409
Score = 87.4 bits (213), Expect = 3e-16
Identities = 103/422 (24%), Positives = 190/422 (44%), Gaps = 59/422 (13%)
Query: 12 LVLYGRDYKLTRADVLIEGDKIVEVKR--NINK--PADEVLDVSK-SLVIPSFINAHTHS 66
L L D+ + + DKI+E+ N+ K P +++ K S+++P+FIN HTH
Sbjct: 9 LFLCDEDFTILENQAFVFEDKILELGELDNLKKKYPKAKIIKTPKNSVILPAFINPHTHL 68
Query: 67 PMVILRGLAEDVPLMEWLQEYIWPVERKLRRKDVYWGSKLALI-----EMAHSGTSTFVD 121
+ WL+ I R + +K LI +M SG T +
Sbjct: 69 EFSANSTTLHFGEFLIWLKSVI------NSRSILNAQAKEELILQSIKKMQKSGIGTIGE 122
Query: 122 MYFH---MEEIAKATEEVGLRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSS--- 175
+ ++ KA+ + G+R ++ ++ + +K EF+K+ ++S
Sbjct: 123 ISSFGSDLDPCLKASHK-GMRIVFFNEILGTNENQVE-------DKKQEFLKRFENSLKF 174
Query: 176 KVNFILAP---HAPYTCSFDCLRWVSEKSREWNSLVTIHLAETQDEIKIIREKYG----- 227
K +F + H+PY+ + + +++ N L + H E++ E +RE G
Sbjct: 175 KNDFFIPAISIHSPYSTHPSLAHFALDLAKKQNLLASTHFLESKAENIWLRESKGGFKKW 234
Query: 228 -------KSPVDVLEDVGLLNE--KLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLG 278
P+ +D L + + + H ++L + + + +I HC SN L
Sbjct: 235 LENFTLHPKPLYTPKDFVKLFKGVRTLFTHCVYLKEYEW--LDKNLHSITHCAFSNRLLS 292
Query: 279 SGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDPSIVK-SEDIFR 337
+K AL++ +N+ LGTDG +SN +L +L EMR A+LL IH++ +++ + + +
Sbjct: 293 QKSLDLKTALKSGLNIHLGTDGLSSNISLSLLDEMR-ANLL---IHKNFDLLELASKLLQ 348
Query: 338 MATLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVG 397
M TL A+AL L G + +G +AD V +L + + A + F +VD L +
Sbjct: 349 MVTLYPARALNLNLGELKKGKIADFNVFELGEC-----DKKQAPLQFILNAKEVDKLFIK 403
Query: 398 GE 399
G+
Sbjct: 404 GK 405
>pir||F71956 hypothetical protein orf1 - Helicobacter pylori (strain J99)
>gi|4154769|gb|AAD05828.1| (AE001462) putative
[Helicobacter pylori J99]
Length = 409
Score = 82.3 bits (200), Expect = 9e-15
Identities = 93/400 (23%), Positives = 169/400 (42%), Gaps = 47/400 (11%)
Query: 31 DKIVEV----KRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQE 86
+KIVE+ + P + S+++P+FINAHTH + + WL
Sbjct: 29 EKIVEIGDYHNLTLKYPHLKAQFFENSVLLPAFINAHTHFEFSNNKASFDYGSFSGWLGS 88
Query: 87 YIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVGLRAYLGYGM 146
+ L ++ + A++ SG + + H+ E+ +E L A +
Sbjct: 89 VLNNGGAIL--ENCQGAIQNAIMAQLKSGVGSVGAISNHLIEV-NLLKESPLNAVV---F 142
Query: 147 VDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNS 206
++ +++ E ++ +K L+ K+ LA HAPY+ D V + +++ S
Sbjct: 143 LEFLGSSYSLEKLKAFEAKFKELKDLEDQKLKAALAVHAPYSVQKDMALSVIQLAKDSQS 202
Query: 207 LVTIHLAETQDEIKIIREKYG----------------------KSPVDVLEDVGLLNEKL 244
L++ H E+ +E++ + G +D+ +D L
Sbjct: 203 LLSTHFLESLEELEWVENSKGWFENFYQRFLKESNFTSLYEGANDYIDMFKDTHTL---- 258
Query: 245 IAAHGIWLSDEDIRKISS--AGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAA 302
H + S E +++I S A + CP SN L +++ E ++V++ TDG +
Sbjct: 259 -FVHNQFASLEALKRIKSQVKNAFLITCPFSNRLLSGKALDLERVREAGLSVSVATDGLS 317
Query: 303 SNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADI 362
SN +L +L E+R A LL H P + ++ AT +GAKAL L G I AD+
Sbjct: 318 SNISLSLLDELR-AFLLS---HNMPLLELAKIALLGATRHGAKALALNNGEIETNKRADL 373
Query: 363 AVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVM 402
+V + A + F +V+ L +GG+ V+
Sbjct: 374 SVFGFNE----KFTKEQAILQFLLHAKEVERLFLGGKRVI 409
>pir||C64553 chlorohydrolase - Helicobacter pylori (strain 26695)
>gi|2313359|gb|AAD07333.1| (AE000545) chlorohydrolase
[Helicobacter pylori 26695]
Length = 409
Score = 81.5 bits (198), Expect = 2e-14
Identities = 93/400 (23%), Positives = 170/400 (42%), Gaps = 47/400 (11%)
Query: 31 DKIVEV----KRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQE 86
+KIVE+ + P + S+++P+FINAHTH + + WL
Sbjct: 29 EKIVEIGDYQSLTLKYPHLKAQFFENSVLLPAFINAHTHFEFSNNKASFDYGSFSGWLGS 88
Query: 87 YIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDMYFHMEEIAKATEEVGLRAYLGYGM 146
+ L ++ + A+ SG + + H+ E+ +E L A +
Sbjct: 89 VLNNGGAIL--ENCQGAIQNAISTQLKSGVGSVGAISNHLIEV-NLLKESPLNAVV---F 142
Query: 147 VDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNS 206
++ +++ E ++ +K L+ K+ LA HAPY+ D V + +++ S
Sbjct: 143 LEFLGSSYSLEKLKAFEAKFKELKDLEDKKLKAALAVHAPYSVQKDMALSVIQLAKDSQS 202
Query: 207 LVTIHLAETQDEIK---------------IIREKYGKS-------PVDVLEDVGLLNEKL 244
L++ H E+ +E++ ++E + KS +D+ +D L
Sbjct: 203 LLSTHFLESLEELEWVENSKGWFENFYQHFLKESHFKSLYKGANDYIDMFKDTHTL---- 258
Query: 245 IAAHGIWLSDEDIRKISS--AGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDGAA 302
H + S E +++I S A + CP SN L +++ E ++V++ TDG +
Sbjct: 259 -FVHNQFASLEALKRIKSQVKNAFLITCPFSNRLLSGQALDLERTKEAGLSVSVATDGLS 317
Query: 303 SNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEGYLADI 362
SN +L +L E+R L H P + ++ AT +GAKAL L G I AD+
Sbjct: 318 SNISLSLLDELRAFLL----THNMPLLELAKIALLGATRHGAKALALNNGEIEANKRADL 373
Query: 363 AVIDLRKAHLLPVNSPLASIIFSARGGDVDTLIVGGEIVM 402
+V + A + F +V+ L +GG+ V+
Sbjct: 374 SVFGFNE----KFTKEQAILQFLLHAKEVECLFLGGKRVI 409
>sp|Q9RW45|Y824_DEIRA HYPOTHETICAL PROTEIN DR0824 >gi|7473523|pir||F75472 probable
hydrolase - Deinococcus radiodurans (strain R1)
>gi|6458536|gb|AAF10399.1|AE001936_8 (AE001936)
hydrolase, putative [Deinococcus radiodurans]
Length = 418
Score = 78.4 bits (190), Expect = 1e-13
Identities = 80/357 (22%), Positives = 144/357 (39%), Gaps = 59/357 (16%)
Query: 35 EVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAEDVPLMEWLQEYIWPVERK 94
E++R A+E + +++ P +NAHTH M A +P +W+ E
Sbjct: 72 ELRRQYPHAAEER---AGAVIAPPPVNAHTHLDMSAYEFQA--LPYFQWIPEV------- 119
Query: 95 LRRKDVYWGSKLALIEMAHSGTSTFV--------DMYFHMEEIAKATEEVGLRAYLGYGM 146
V G L + A +G T D+ + E + L L + +
Sbjct: 120 -----VIRGRHLRGVAAAQAGADTLTRLGAGGVGDIVWAPEVMDALLAREDLSGTLYFEV 174
Query: 147 VDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPHAPYTCSFDCLRWVSEKSREWNS 206
++ ++ ++ L + ++L+ + L+PH P+T S +R +S+ +
Sbjct: 175 LNPFPDKADEVFAAARTHLERW-RRLERPGLRLGLSPHTPFTVSHRLMRLLSDYAAGEGL 233
Query: 207 LVTIHLAETQDEIKIIREKYGK--------------------------SPVDVLEDVGLL 240
+ IH+AE E+++ R G +PV L+++G+L
Sbjct: 234 PLQIHVAEHPTELEMFRTGGGPLWDNRMPALYPHTLAEVIGREPGPDLTPVRYLDELGVL 293
Query: 241 NEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALGTDG 300
+ H + ++ +DI +++ AG + CP SN L G F V VALGTD
Sbjct: 294 AARPTLVHMVNVTPDDIARVARAGCAVVTCPRSNHHLECGTFDWPAFAAAGVEVALGTDS 353
Query: 301 AASNNTLDILREMRLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGVIAEG 357
AS TL++ E+ A L + DP + + R A G + +G + + G
Sbjct: 354 VASGETLNVREEVTFARQLYPGL--DPRV-----LVRAAVKGGQRVVGGRTPFLRRG 403
>pir||C83008 conserved hypothetical protein PA5106 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951402|gb|AAG08491.1|AE004923_7 (AE004923)
conserved hypothetical protein [Pseudomonas aeruginosa]
Length = 453
Score = 75.3 bits (182), Expect = 1e-12
Identities = 94/431 (21%), Positives = 175/431 (39%), Gaps = 53/431 (12%)
Query: 33 IVEVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAE-----DVPLMEWLQEY 87
+ E++ + N E L V+P N H+H+ + GLAE + W +E
Sbjct: 29 LAEIRPDANADGAERLG---GAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTW-REL 84
Query: 88 IWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDM-YFHME--------------EIAKA 132
++ + +L + + + IEM +G + + Y H + I++A
Sbjct: 85 MYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRA 144
Query: 133 TEEVG--------LRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSKVNFILAPH 184
G L ++ G+G + ++R I E +++ L + A H
Sbjct: 145 ASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEA-----YLELLQRLRAPLEAAGH 199
Query: 185 APYTCSFDCLRWVSEK-------SREWNSLVTIHLAETQDEIKIIREKYGKSPVDVLEDV 237
+ C F LR V+ + + + V IH+AE Q E+ + G+ P+ L +
Sbjct: 200 SLGLC-FHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYEN 258
Query: 238 GLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKALENNVNVALG 297
++++ H ++ ++ +GA C ++ LG G+FP L + +G
Sbjct: 259 VAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIG 318
Query: 298 TDGAASNNTLDILREM----RLASLLQKVIHRDPSIVKSEDIFRMATLNGAKALGLKAGV 353
+D S + ++ LR + RL + ++RD + ++ A GA+ALG G
Sbjct: 319 SDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGS 378
Query: 354 IAEGYLADIAVIDLRKAHLLPVNSPLASIIFSARGGD--VDTLIVGGEIVMLDSELLTVD 411
+A G AD+ V+D +L + GGD V ++V G V+ D
Sbjct: 379 LAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGR--HAG 436
Query: 412 EEKVIDKFLEV 422
EE+ F++V
Sbjct: 437 EERSARAFVQV 447
>pir||T21966 hypothetical protein F38E11.3 - Caenorhabditis elegans
>gi|3876923|emb|CAA92772.1| (Z68342) contains similarity
to Pfam domain: PF01685 (Chlorohydrolase), Score=427.4,
E-value=4.3e-125, N=1 [Caenorhabditis elegans]
Length = 313
Score = 73.0 bits (176), Expect = 6e-12
Identities = 77/317 (24%), Positives = 135/317 (42%), Gaps = 38/317 (11%)
Query: 111 MAHSGTSTFVDMYF--HMEE-------IAKATEEVGLRAYLG---YGMVDLDDEEKRKIE 158
M ++G +T + ++ H E+ + +A + G+R L Y D ++
Sbjct: 1 MINAGITTVGEFHYVHHSEQKFDLDQLVIQAAIDAGIRIVLLQTLYERAGFDSPAVHPVQ 60
Query: 159 MRETEKLYEFIKKLDS-------SKVNFILAPHAPYTCSFDCLRWVSEKSREWNSLVTIH 211
R +FI L+ +V +A H+ F+ ++ + E + E IH
Sbjct: 61 ERFIASYEDFIGNLEKLRKEKTHERVQIGVAAHSARAVPFENIKKLFEYASEHKIPFHIH 120
Query: 212 LAETQDEI----KIIREKYGKSPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATI 267
L E EI K I +K G P D++ LNE A H + ++ S GA +
Sbjct: 121 LEEQPKEIFDCQKFIGQKQG--PSDLILSKMHLNEYFTAVHSTFTPANNMLLFSKLGANV 178
Query: 268 AHCPASNMKLGSGVFPMKKALENNVNVALGTDGAASNNTLDILREMRLASLLQKVIHRDP 327
+ CP + LG G+ + ++ ++ GTD NN + L EMR A Q++++
Sbjct: 179 SICPCTEGYLGDGI----PRINESLKISFGTD---CNNRICFLEEMRWACFSQQMLNNSR 231
Query: 328 SI--VKSEDIFRMATLNGAKALGL--KAGVIAEGYLADIAVIDLRKAHL--LPVNSPLAS 381
S+ + E + AT++GA+AL L K G + G D L L ++ + S
Sbjct: 232 SVCGLSPEKLLLCATIDGARALSLTSKTGSLEVGKYFDAISFSLDSPLLENSLADTLIDS 291
Query: 382 IIFSARGGDVDTLIVGG 398
++ SA ++ + V G
Sbjct: 292 LVLSAGNREISNVFVSG 308
>pir||T46986 hypothetical protein [imported] - Yersinia pestis
>gi|4106574|emb|CAA21329.1| (AL031866) ORF 7, len: 456
aa, highly similar to AF060075_3, Myxococcus xanthus
sdeAB operon, atrazine chlorohydrolase homolog, 36.6%
identity in 421 aa overlap, Fasta scores opt:891, E():0
[Yersinia pestis]
Length = 456
Score = 72.2 bits (174), Expect = 1e-11
Identities = 92/427 (21%), Positives = 176/427 (40%), Gaps = 57/427 (13%)
Query: 24 ADVLIEGDKIVEVKRNINKPADEVLDVSKSLVIPSFINAHTHSPMVILRGLAE---DVPL 80
ADV I D++ +++R + V V+P N H+H+ ++ GLAE D
Sbjct: 17 ADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLPGMPNLHSHAFQRMMSGLAEVAGDPQD 76
Query: 81 MEWL-QEYIWPVERKLRRKDVYWGSKLALIEMAHSGTSTFVDM-YFHME----------- 127
W ++ ++ + ++L + V ++ IEM G + + Y H
Sbjct: 77 SFWTWRDLMYRLVQQLTPEQVGVIARQLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGE 136
Query: 128 ---EIAKATEEVG--------LRAYLGYGMVDLDDEEKRKIEMRETEKLYEFIKKLDSSK 176
++++A ++ G L +Y G+G + R I+ E+ ++++ +
Sbjct: 137 MTAQLSQAAQDAGIGMTLLPVLYSYAGFGAQPAQQGQSRFIQDTES-----YLRQQQVIR 191
Query: 177 VNFILAPHAPYTCSFDCLRWVSEKSREWNSL--------VTIHLAETQDEIKIIREKYGK 228
P F LR V E S+ L V IH+AE Q E+ G+
Sbjct: 192 RQLANQPLQNQGLCFHSLRAV-ELSQMQQILHVSDKQLPVHIHIAEQQKEVNDCLAWCGQ 250
Query: 229 SPVDVLEDVGLLNEKLIAAHGIWLSDEDIRKISSAGATIAHCPASNMKLGSGVFPMKKAL 288
PV L ++ + H L ++ ++++ A CP + LG G+FP +
Sbjct: 251 RPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLGDGIFPGVDYI 310
Query: 289 ENNVNVALGTDGAASNNTLDILREMRLASLLQKV---------IHRDPSIVKSEDIFRMA 339
+ +G+D S+ +LD++ E+R Q++ R P++ ++ ++ A
Sbjct: 311 HHQGRWGIGSD---SHVSLDVVEELRWLEYGQRLRDQRRNRLTCERQPAV--ADLLYSQA 365
Query: 340 TLNGAKALGLKAGVIAEGYLADIAVIDLRKAHLLPVNSP--LASIIFSARGGDVDTLIVG 397
G +A G + +A GY AD V+D ++ S L +F+ + + V
Sbjct: 366 LAGGRQACGRQISQLAVGYRADWLVLDGDDPYIAGTRSASLLNRWLFAGGKSQIRDVYVA 425
Query: 398 GEIVMLD 404
G+ V++D
Sbjct: 426 GKAVIVD 432
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.137 0.387
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 150897213
Number of Sequences: 2977
Number of extensions: 6226161
Number of successful extensions: 17297
Number of sequences better than 1.0e-10: 54
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 17141
Number of HSP's gapped (non-prelim): 60
length of query: 425
length of database: 189,106,746
effective HSP length: 58
effective length of query: 367
effective length of database: 154,394,500
effective search space: 56662781500
effective search space used: 56662781500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)