BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0459 (nth) DE:endonuclease III (nth)
(222 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75109 endonuclease III (nth) PAB0459 - Pyrococcus abyssi (... 455 e-127
pir||F71025 probable endonuclease III - Pyrococcus horikoshii >g... 416 e-116
pir||B69202 endonuclease III - Methanobacterium thermoautotrophi... 203 1e-51
sp|Q9WYK0|END3_THEMA ENDONUCLEASE III (DNA-(APURINIC OR APYRIMID... 182 4e-45
emb|CAC11921.1| (AL445065) endonuclease III related protein [The... 176 2e-43
gi|11499282 endonuclease III (nth) [Archaeoglobus fulgidus] >gi|... 173 1e-42
pir||H70325 endonuclease III - Aquifex aeolicus >gi|2982981|gb|A... 168 5e-41
pir||B75537 endonuclease III - Deinococcus radiodurans (strain R... 168 7e-41
sp|P39788|END3_BACSU PROBABLE ENDONUCLEASE III (DNA-(APURINIC OR... 160 2e-38
dbj|BAA90651.1| (AB003153) End3 [Paenibacillus polymyxa] 157 1e-37
pir||F70344 endonuclease III - Aquifex aeolicus >gi|2983139|gb|A... 153 2e-36
dbj|BAB05417.1| (AP001512) endonuclease III (DNA repair) [Bacill... 150 1e-35
sp|P73715|END3_SYNY3 ENDONUCLEASE III (DNA-(APURINIC OR APYRIMID... 149 2e-35
sp|Q58030|Y613_METJA PUTATIVE ENDONUCLEASE MJ0613 >gi|2826298|gb... 141 5e-33
pir||E64376 endonuclease III - Methanococcus jannaschii 141 5e-33
pir||H83208 endonuclease III PA3495 [imported] - Pseudomonas aer... 138 8e-32
pir||T36554 probable endonuclease - Streptomyces coelicolor >gi|... 138 8e-32
pir||C81914 probable endonuclease III NMA0711 [imported] - Neiss... 135 4e-31
sp|O05956|END3_RICPR ENDONUCLEASE III (DNA-(APURINIC OR APYRIMID... 134 9e-31
pir||D81187 endonuclease III NMB0533 [imported] - Neisseria meni... 133 1e-30
gb|AAA86508.1| (U22181) ultraviolet N-glycosylase/AP lyase [Micr... 132 4e-30
sp|P46303|UVEN_MICLU ULTRAVIOLET N-GLYCOSYLASE/AP LYASE (UV ENDO... 132 4e-30
pir||A82252 endonuclease III VC1011 [imported] - Vibrio cholerae... 127 1e-28
gi|6679146 thymine glycol DNA glycosylase/AP lyase [Mus musculus... 125 4e-28
sp|P20625|END3_ECOLI ENDONUCLEASE III (DNA-(APURINIC OR APYRIMID... 125 6e-28
sp|P44319|END3_HAEIN ENDONUCLEASE III (DNA-(APURINIC OR APYRIMID... 125 6e-28
sp|O69642|END3_MYCTU ENDONUCLEASE III (DNA-(APURINIC OR APYRIMID... 124 7e-28
pir||A64593 endonuclease III - Helicobacter pylori (strain 26695... 123 1e-27
pir||B71919 endonuclease III - Helicobacter pylori (strain J99) ... 123 2e-27
emb|CAA70865.1| (Y09687) endonuclease III homologue 1 [Homo sapi... 120 1e-26
gi|4505471 nth (E.coli endonuclease III)-like 1 [Homo sapiens] >... 120 1e-26
gb|AAK40470.1| DNA endonuclease III, probable (ntH-1) [Sulfolobu... 120 1e-26
pir||S75373 probable DNA-(apurinic or apyrimidinic site) lyase (... 120 1e-26
gb|AAC51136.1| (U81285) endonuclease III [Homo sapiens] >gi|1881... 120 1e-26
gb|AAB41534.1| (U79718) endonuclease III homolog 1, hNTH1 [Homo ... 120 1e-26
gb|AAG28772.1|AF300990_1 (AF300990) endonuclease III [Salmonella... 120 2e-26
gb|AAF53949.1| (AE003668) CG9272 gene product [Drosophila melano... 118 4e-26
sp|P54137|END3_CAEEL PROBABLE ENDONUCLEASE III HOMOLOG (DNA-(APU... 118 5e-26
pir||H70192 endonuclease III (nth) homolog - Lyme disease spiroc... 118 7e-26
pir||E82780 endonuclease III XF0647 [imported] - Xylella fastidi... 116 2e-25
gb|AAG19103.1| (AE005008) endonuclease III; NthA2 [Halobacterium... 114 8e-25
gb|AAD26474.1|AC007169_6 (AC007169) putative endonuclease [Arabi... 114 1e-24
emb|CAC16135.1| (AJ272248) endonuclease III homologue [Arabidops... 113 2e-24
sp|O83754|END3_TREPA ENDONUCLEASE III (DNA-(APURINIC OR APYRIMID... 112 4e-24
pir||B81407 endonuclease III Cj0595c [imported] - Campylobacter ... 104 7e-22
gb|AAF29397.1|AC009999_17 (AC009999) Contains similarity to an e... 104 9e-22
sp|P57219|END3_BUCAI ENDONUCLEASE III (DNA-(APURINIC OR APYRIMID... 103 2e-21
gb|AAG18952.1| (AE004996) endonuclease III; NthA1 [Halobacterium... 98 9e-20
gb|AAF35322.1|AF222908_2 (AF222908) Ntg1 [Candida albicans] 97 2e-19
pir||A72682 probable A/G-specific adenine glycosylase APE0875 - ... 95 8e-19
pir||C75459 probable endonuclease III - Deinococcus radiodurans ... 93 3e-18
gb|AAF37269.1|AF222334_1 (AF222334) putative DNA glycosylase [Py... 93 3e-18
pir||D72029 endonuclease III CP1032 [imported] - Chlamydophila p... 91 9e-18
sp|Q09907|END3_SCHPO ENDONUCLEASE III HOMOLOG (DNA-(APURINIC OR ... 89 4e-17
pir||E71969 a/g-specific adenine glycosylase - Helicobacter pylo... 88 8e-17
pir||F64537 A/G-specific adenine glycosylase - Helicobacter pylo... 88 1e-16
pir||B81745 endonuclease III TC0069 [imported] - Chlamydia murid... 87 1e-16
pir||A72082 adenine glycosylase - Chlamydophila pneumoniae (stra... 83 2e-15
pir||C71482 probable endonuclease III - Chlamydia trachomatis (s... 83 3e-15
pir||D75275 endonuclease III - Deinococcus radiodurans (strain R... 83 3e-15
gi|10954471 ORF10 [Methanobacterium thermoautotrophicum] >gi|232... 81 1e-14
pir||S30312 endonuclease III homolog - Methanobacterium thermofo... 81 1e-14
sp|P57617|MUTY_BUCAI A/G-SPECIFIC ADENINE GLYCOSYLASE >gi|100392... 80 3e-14
gb|AAC46007.1| (AF009362) putative endonuclease III [Clostridium... 79 5e-14
dbj|BAB04650.1| (AP001510) adenine glycosylase [Bacillus halodur... 77 2e-13
gb|AAF37270.1|AF222335_1 (AF222335) U/G and T/G mismatch-specifi... 76 4e-13
pir||A81709 A/G-specific adenine glycosylase TC0383 [imported] -... 76 4e-13
pir||B69165 endonuclease III homolog - Methanobacterium thermoau... 75 7e-13
pir||C72770 probable DNA-(apurinic or apyrimidinic site)lyase AP... 75 1e-12
pir||G83003 A / G specific adenine glycosylase PA5147 [imported]... 74 1e-12
sp|P17802|MUTY_ECOLI A/G-SPECIFIC ADENINE GLYCOSYLASE >gi|96182|... 74 2e-12
pdb|1MUY|A Chain A, Catalytic Domain Of Muty From Escherichia Coli 74 2e-12
gi|6912520 mutY (E. coli) homolog [Homo sapiens] >gi|6691521|dbj... 73 2e-12
dbj|BAA89337.1| (AB032921) hMYHalpha2 [Homo sapiens] 73 2e-12
dbj|BAA89339.1| (AB032923) hMYHalpha4 [Homo sapiens] >gi|6691539... 73 2e-12
dbj|BAA89340.1| (AB032924) hMYHbeta1 [Homo sapiens] 73 2e-12
dbj|BAA89341.1| (AB032925) hMYHbeta3 [Homo sapiens] >gi|6691533|... 73 2e-12
gb|AAC50618.1| (U63329) mutY homolog [Homo sapiens] >gi|6691525|... 73 2e-12
dbj|BAA89343.1| (AB032927) hMYHgamma2 [Homo sapiens] 73 2e-12
sp|P44320|MUTY_HAEIN A/G-SPECIFIC ADENINE GLYCOSYLASE >gi|107380... 73 4e-12
pir||D82320 A/G-specific adenine glycosylase VC0452 [imported] -... 73 4e-12
pdb|1MUN| Catalytic Domain Of Muty From Escherichia Coli D138n... 72 6e-12
gb|AAG19811.1| (AE005065) A/G specific adenine glycosylase, repa... 71 8e-12
pir||A64479 DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99... 71 1e-11
sp|Q05869|MUTY_SALTY A/G-SPECIFIC ADENINE GLYCOSYLASE >gi|538800... 70 2e-11
emb|CAB37760.1| (AJ239649) MutY protein [Helicobacter pylori] 70 2e-11
emb|CAB37762.1| (AJ239651) MutY protein [Helicobacter pylori] 70 2e-11
pir||A69802 A/G-specific adenine glycosylase homolog yfhQ - Baci... 70 2e-11
emb|CAB37759.1| (AJ239648) MutY protein [Helicobacter pylori] 70 2e-11
pir||B71557 probable adenine glycosylase - Chlamydia trachomatis... 69 3e-11
pir||B81258 A/G-specific adenine glycosylase (EC 3.2.2.-) Cj1620... 69 3e-11
emb|CAB37763.1| (AJ239652) MutY protein [Helicobacter pylori] 69 4e-11
emb|CAB37767.1| (AJ239656) MutY protein [Helicobacter pylori] 69 4e-11
emb|CAB37761.1| (AJ239650) MutY protein [Helicobacter pylori] 69 6e-11
emb|CAB37765.1| (AJ239654) MutY protein [Helicobacter pylori] 69 6e-11
emb|CAB37757.1| (AJ239646) MutY protein [Helicobacter pylori] 68 7e-11
emb|CAB37758.1| (AJ239647) MutY protein [Helicobacter pylori] 68 7e-11
emb|CAB37764.1| (AJ239653) MutY protein [Helicobacter pylori] 68 7e-11
emb|CAB37768.1| (AJ239657) MutY protein [Helicobacter pylori] 68 1e-10
emb|CAB37769.1| (AJ239658) MutY protein [Helicobacter pylori] 68 1e-10
emb|CAB37774.1| (AJ239663) MutY protein [Helicobacter pylori] 68 1e-10
>pir||A75109 endonuclease III (nth) PAB0459 - Pyrococcus abyssi (strain Orsay)
>gi|5458097|emb|CAB49586.1| (AJ248285) endonuclease III
(nth) [Pyrococcus abyssi]
Length = 222
Score = 455 bits (1159), Expect = e-127
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MGKSSSLSERERALKIVQILKSTYPRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELF 60
MGKSSSLSERERALKIVQILKSTYPRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELF
Sbjct: 1 MGKSSSLSERERALKIVQILKSTYPRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELF 60
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK
Sbjct: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
Query: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEW 180
LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEW
Sbjct: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEW 180
Query: 181 IYVNHAMVDHGKSVCRPIKPRCDECPLKELCPRIGVQANSNQ 222
IYVNHAMVDHGKSVCRPIKPRCDECPLKELCPRIGVQANSNQ
Sbjct: 181 IYVNHAMVDHGKSVCRPIKPRCDECPLKELCPRIGVQANSNQ 222
>pir||F71025 probable endonuclease III - Pyrococcus horikoshii
>gi|3257923|dbj|BAA30606.1| (AP000006) 222aa long
hypothetical endonuclease III [Pyrococcus horikoshii]
Length = 222
Score = 416 bits (1059), Expect = e-116
Identities = 200/222 (90%), Positives = 212/222 (95%)
Query: 1 MGKSSSLSERERALKIVQILKSTYPRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELF 60
M K+ LSERERALKI++ILKSTYPR+ HVSGDPYKTLIRCIISQRNRDEVTDRVSEELF
Sbjct: 1 MNKNLPLSERERALKIIKILKSTYPRKNHVSGDPYKTLIRCIISQRNRDEVTDRVSEELF 60
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
KRYP+IE+IASASVEEMQNFL+SLKVGLWRSKGKWIVETSRIIL+KY GRVPDKFEELIK
Sbjct: 61 KRYPTIESIASASVEEMQNFLKSLKVGLWRSKGKWIVETSRIILKKYNGRVPDKFEELIK 120
Query: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEW 180
LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLK LIPREEW
Sbjct: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKSLIPREEW 180
Query: 181 IYVNHAMVDHGKSVCRPIKPRCDECPLKELCPRIGVQANSNQ 222
IYVNHAMVDHGKSVC+PIKPRC ECPL+ LCP+IGVQ S+Q
Sbjct: 181 IYVNHAMVDHGKSVCKPIKPRCWECPLRGLCPKIGVQDTSSQ 222
>pir||B69202 endonuclease III - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621854|gb|AAB85267.1| (AE000855)
endonuclease III [Methanobacterium thermoautotrophicum]
Length = 233
Score = 203 bits (512), Expect = 1e-51
Identities = 102/196 (52%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Query: 16 IVQILKSTYPRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVE 75
I+ L+S Y DPY+ LIR I+SQR RDE TD + LF+RYPSIE +A A +E
Sbjct: 27 IIGGLRSVYSMRVFEDRDPYRVLIRTILSQRTRDENTDEATASLFERYPSIEDVAYAPLE 86
Query: 76 EMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAY 135
E++ +R K G + K + + E SRIILE+Y G+VPD EL+KLPG+GRK AN VL Y
Sbjct: 87 EIEALIR--KAGFYHVKARRVREVSRIILEEYDGKVPDDINELLKLPGVGRKTANCVLVY 144
Query: 136 GFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVC 195
FG PAIPVDTHV+RIS R+GL +PEE E L ++IPRE WI +N MV G+ +C
Sbjct: 145 AFGRPAIPVDTHVHRISNRIGLVD-TRTPEETERALMKVIPREYWIELNDLMVQFGQDIC 203
Query: 196 RPIKPRCDECPLKELC 211
RP+ PR +ECP+ + C
Sbjct: 204 RPLGPRHEECPIADHC 219
>sp|Q9WYK0|END3_THEMA ENDONUCLEASE III (DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE)
>gi|7437109|pir||F72387 endonuclease III - Thermotoga
maritima (strain MSB8)
>gi|4980869|gb|AAD35453.1|AE001716_16 (AE001716)
endonuclease III [Thermotoga maritima]
Length = 213
Score = 182 bits (456), Expect = 4e-45
Identities = 91/188 (48%), Positives = 130/188 (68%), Gaps = 4/188 (2%)
Query: 24 YPRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRS 83
+PR H DP++ LI ++SQR RDE T++ S++LF+ Y + + +A A E++ + ++
Sbjct: 13 FPRN-HKETDPFRVLISTVLSQRTRDENTEKASKKLFEVYRTPQELAKAKPEDLYDLIK- 70
Query: 84 LKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIP 143
+ G++R K + IVE SRI++EKY GRVPD EEL+KLPG+GRK ANIVL GF PA+
Sbjct: 71 -ESGMYRQKAERIVEISRILVEKYGGRVPDSLEELLKLPGVGRKTANIVLWVGFKKPALA 129
Query: 144 VDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCD 203
VDTHV+RIS RLG +PEE EE LK+L+P + W +N +MV+ G+ +C+P P C+
Sbjct: 130 VDTHVHRISNRLGWVK-TRTPEETEEALKKLLPEDLWGPINGSMVEFGRRICKPQNPLCE 188
Query: 204 ECPLKELC 211
EC LK C
Sbjct: 189 ECFLKNHC 196
>emb|CAC11921.1| (AL445065) endonuclease III related protein [Thermoplasma
acidophilum]
Length = 197
Score = 176 bits (442), Expect = 2e-43
Identities = 85/189 (44%), Positives = 121/189 (63%), Gaps = 7/189 (3%)
Query: 25 PRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSL 84
P R V DP+ LI ++SQR +DE TD + L+++Y I+ +A A +E+ +
Sbjct: 2 PAHRFVFRDPFWMLITTVLSQRTKDETTDEAARSLYEKYRDIDGLADADPDEVGRIIS-- 59
Query: 85 KVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPV 144
KVG WR K + +VE +RII ++Y RVPD +EL+ LPG+G K A +VLA GF PAI V
Sbjct: 60 KVGFWRVKSRKVVEIARIIRDRYNYRVPDSIDELVSLPGVGLKTAKVVLAEGFNRPAIAV 119
Query: 145 DTHVYRISRRLGLAPWDA--SPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRC 202
DTHV+RIS R+G W + +PEE E L+ +IP + + N MV+ GK++CRP++P C
Sbjct: 120 DTHVFRISHRIG---WSSARTPEETSEELERIIPVDLQVGFNPMMVEFGKAICRPVRPLC 176
Query: 203 DECPLKELC 211
D CP+ E C
Sbjct: 177 DRCPVSEYC 185
>gi|11499282 endonuclease III (nth) [Archaeoglobus fulgidus]
>gi|7437104|pir||C69461 endonuclease III (nth) homolog -
Archaeoglobus fulgidus >gi|2648861|gb|AAB89556.1|
(AE000986) endonuclease III (nth) [Archaeoglobus
fulgidus]
Length = 209
Score = 173 bits (435), Expect = 1e-42
Identities = 92/184 (50%), Positives = 120/184 (65%), Gaps = 5/184 (2%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
P++ L+ ++S R RDE T R ++ LF + E + S EE+ ++ VG +R K
Sbjct: 31 PFQHLVAALLSSRTRDEATVRAAQNLFAKVKKPEDLLKLSEEEIAELIKG--VGFYRVKA 88
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
K + E ++ ++E Y VP FEEL+KLPGIGRK AN+VLAY IPAIPVDTHV+RI+
Sbjct: 89 KRLKELAKKLVEDYSSEVPLSFEELVKLPGIGRKSANVVLAYS-DIPAIPVDTHVHRIAN 147
Query: 154 RLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCPR 213
RLG A PEE EE LK L P E W VN AMV G++VC+P KP CDECP+K CPR
Sbjct: 148 RLGWAR-TTKPEETEEVLKRLFPLEFWEKVNRAMVGFGQTVCKPQKPLCDECPIKG-CPR 205
Query: 214 IGVQ 217
+GV+
Sbjct: 206 VGVK 209
>pir||H70325 endonuclease III - Aquifex aeolicus >gi|2982981|gb|AAC06594.1|
(AE000682) endonuclease III [Aquifex aeolicus]
Length = 213
Score = 168 bits (421), Expect = 5e-41
Identities = 85/211 (40%), Positives = 134/211 (63%), Gaps = 11/211 (5%)
Query: 9 ERERALKIVQILKSTYPRER----HVSG----DPYKTLIRCIISQRNRDEVTDRVSEELF 60
+RE K+++ILK +P+ H+ DP++ L+ ++S R +DE+T RV + F
Sbjct: 2 KREDVPKVLEILKREFPKWNAPVVHMIAQHDKDPFRVLVCALLSTRTKDELTWRVCKRFF 61
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
++ S E + S +E++ + VG +R K K + E +I++EKY G+VPD EEL+K
Sbjct: 62 EKVKSPEDLIKLSEKEIEELI--YPVGFYRVKAKQLKEIGKILIEKYGGKVPDTLEELLK 119
Query: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEW 180
LPG+GRK AN+VL+ GF PAI VD HV+RI R L +PEE E +L E++P+E W
Sbjct: 120 LPGVGRKVANLVLSKGFNKPAIVVDVHVHRIVNRWCLVK-TKTPEETERKLMEIVPKELW 178
Query: 181 IYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
+N+ +V G+++C P KP+C+ECP+++ C
Sbjct: 179 SDINYLLVAFGQTICLPRKPKCEECPVEKYC 209
>pir||B75537 endonuclease III - Deinococcus radiodurans (strain R1)
>gi|6457961|gb|AAF09870.1|AE001890_2 (AE001890)
endonuclease III [Deinococcus radiodurans]
Length = 225
Score = 168 bits (420), Expect = 7e-41
Identities = 78/210 (37%), Positives = 134/210 (63%), Gaps = 5/210 (2%)
Query: 10 RERALKIVQILKSTYP--RERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIE 67
R RA +++ L YP R V P++ L+ ++S + D + + LF YP
Sbjct: 15 RARAPQVLSALGRLYPDARTELVFNTPFELLVATVLSAQATDVSVNAATPALFAAYPDAH 74
Query: 68 AIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRK 127
A++ A+ ++++ ++RS +GL+R K K + +R+++E++ G VP+ F+ ++ LPG GRK
Sbjct: 75 ALSQATADDIEPYIRS--IGLYRGKAKNLAALARLLVERHGGEVPNDFDAVVALPGAGRK 132
Query: 128 CANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAM 187
AN+VL+ + PAI VDTHV R++RRLGL+ +P++VE L++L PR+ W++++HA+
Sbjct: 133 TANVVLSNAYDYPAIAVDTHVGRLARRLGLSV-QTNPDKVEADLQKLFPRDRWVFLHHAL 191
Query: 188 VDHGKSVCRPIKPRCDECPLKELCPRIGVQ 217
+ HG+ VC KP+C C L CP++GV+
Sbjct: 192 ILHGRRVCHARKPQCPSCELASFCPKVGVE 221
>sp|P39788|END3_BACSU PROBABLE ENDONUCLEASE III (DNA-(APURINIC OR APYRIMIDINIC SITE)
LYASE) >gi|2126933|pir||I40525 endonuclease III (DNA
repair) nth - Bacillus subtilis
>gi|533099|gb|AAA80005.1| (U11289) endonuclease III
[Bacillus subtilis] >gi|1146249|gb|AAB38457.1| (L47709)
endonuclease III [Bacillus subtilis]
>gi|2634652|emb|CAB14150.1| (Z99115) endonuclease III
[Bacillus subtilis]
Length = 219
Score = 160 bits (400), Expect = 2e-38
Identities = 75/182 (41%), Positives = 119/182 (65%), Gaps = 2/182 (1%)
Query: 30 VSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLW 89
V +P++ ++ +S + D + +RV++ LF++Y E + +EE+Q ++S +GL+
Sbjct: 26 VHSNPFELVVAVALSAQCTDALVNRVTKTLFQKYKRPEDYLAVPLEELQQDIKS--IGLY 83
Query: 90 RSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVY 149
R+K K I + S++I+E Y G VP +EL+KLPG+GRK AN+V++ FG+PAI VDTHV
Sbjct: 84 RNKAKNIQKLSKMIIEDYGGEVPRDRDELVKLPGVGRKTANVVVSVAFGVPAIAVDTHVE 143
Query: 150 RISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKE 209
R+S+RLG+ W S EVE+ L +P+E+W +H ++ G+ C+ PRC ECPL
Sbjct: 144 RVSKRLGICRWKDSVLEVEKTLMRKVPKEDWSVTHHRLIFFGRYHCKAQSPRCAECPLLS 203
Query: 210 LC 211
LC
Sbjct: 204 LC 205
>dbj|BAA90651.1| (AB003153) End3 [Paenibacillus polymyxa]
Length = 224
Score = 157 bits (393), Expect = 1e-37
Identities = 69/177 (38%), Positives = 120/177 (66%), Gaps = 2/177 (1%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
++ I ++S + D++ ++V+ +LF++Y S E + +EE++ +R ++GL+R+K K
Sbjct: 30 FELTIAVLLSAQCSDQMVNKVTADLFQKYKSPEDYLAVPLEELEQDIR--RIGLYRNKAK 87
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRR 154
I RI++++Y G +P + ++L+KLPG+GRK AN+V++ F +PAI VDTHV R+S+R
Sbjct: 88 HIHNLCRILIDQYGGEIPSEHDQLVKLPGVGRKTANVVVSTAFDVPAIAVDTHVERVSKR 147
Query: 155 LGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
LG A WD S EVE++L + +PR+EW +H ++ G+ C+ P+C CPL ++C
Sbjct: 148 LGFAGWDDSVLEVEKKLMKRVPRDEWSVTHHRLIFFGRYHCKAQNPQCQVCPLLDVC 204
>pir||F70344 endonuclease III - Aquifex aeolicus >gi|2983139|gb|AAC06742.1|
(AE000692) endonuclease III [Aquifex aeolicus]
Length = 232
Score = 153 bits (382), Expect = 2e-36
Identities = 74/204 (36%), Positives = 130/204 (63%), Gaps = 5/204 (2%)
Query: 10 RERALKIVQILKSTY--PRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIE 67
R +A++IV+ L+ Y PR + ++ L+ I++ + D+V ++VS+E FK+Y + +
Sbjct: 21 RRKAVEIVKRLEKVYLNPRLELEYENAFQLLVMAILAAQESDKVVNKVSKEFFKKYKTPQ 80
Query: 68 AIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRK 127
IA A++EE++ L+ + +R K K I E ++E YKG VP EL+KLPG+GRK
Sbjct: 81 DIARANLEELEEDLKH--INFYRRKAKLIKECCEKLIELYKGEVPKSVGELVKLPGVGRK 138
Query: 128 CANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAM 187
AN+V+ + +PAI VD HV+R+ R+ L+ +P+++E L E++P+E W + +
Sbjct: 139 TANMVIGGAYNLPAIIVDRHVHRVVERISLSK-QKNPDKMEMELSEIVPQELWTKFSLLL 197
Query: 188 VDHGKSVCRPIKPRCDECPLKELC 211
++HGK++C+ P C++CP+ +LC
Sbjct: 198 LNHGKTICKARNPECEKCPILDLC 221
>dbj|BAB05417.1| (AP001512) endonuclease III (DNA repair) [Bacillus halodurans]
Length = 218
Score = 150 bits (376), Expect = 1e-35
Identities = 70/179 (39%), Positives = 116/179 (64%), Gaps = 2/179 (1%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
+P++ LI ++S + D + ++V+ LF +Y + E + +EE++ +RS +GL+R+K
Sbjct: 29 NPFELLIAVVLSAQCTDALVNKVTPRLFAKYKTPEDYIAVPLEELEQDIRS--IGLYRNK 86
Query: 93 GKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRIS 152
K I + + +LE+Y G VP +EL+KL G+GRK AN+V + FG+PAI VDTHV R+S
Sbjct: 87 AKNIKKLCQSLLEQYGGEVPQDRDELVKLAGVGRKTANVVASVAFGVPAIAVDTHVERVS 146
Query: 153 RRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
+RLG+ W + +VE+ L + IP +EW +H ++ G+ C+ P+CD CPL ++C
Sbjct: 147 KRLGICRWKDNVTQVEQTLMKKIPMDEWSISHHRLIFFGRYHCKAQNPQCDICPLLDMC 205
>sp|P73715|END3_SYNY3 ENDONUCLEASE III (DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE)
>gi|7437097|pir||S77204 endonuclease III - Synechocystis
sp. (strain PCC 6803) >gi|1652843|dbj|BAA17762.1|
(D90908) endonuclease III [Synechocystis sp.]
Length = 219
Score = 149 bits (373), Expect = 2e-35
Identities = 86/209 (41%), Positives = 126/209 (60%), Gaps = 8/209 (3%)
Query: 8 SERERALKIVQILKSTYPRERHVSGD---PYKTLIRCIISQRNRDEVTDRVSEELFKRYP 64
S+++RA +I+ ILK YP S D P + L+ I+S + DE ++V+ LF+RYP
Sbjct: 10 SKKQRATEILLILKKLYPGAT-CSLDYQTPVQLLVATILSAQCTDERVNKVTPALFQRYP 68
Query: 65 SIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGI 124
A+A +E++ + S G +R+K K I R I+E++ G VP + EEL+ LPG+
Sbjct: 69 DANALAYGDRQEIEELIHS--TGFFRNKAKNIQGACRKIVEEFDGEVPQRMEELLTLPGV 126
Query: 125 GRKCANIVLAYGFGIPA-IPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYV 183
RK AN+VLA+ FGI A + VDTHV R+S+RLGL P +E L +LIP+ +W
Sbjct: 127 ARKTANVVLAHAFGILAGVTVDTHVKRLSQRLGLTK-ATDPIRIERDLMKLIPQPDWENF 185
Query: 184 NHAMVDHGKSVCRPIKPRCDECPLKELCP 212
+ ++ HG++VC KP C EC L LCP
Sbjct: 186 SIHIIYHGRAVCAARKPLCGECQLAHLCP 214
>sp|Q58030|Y613_METJA PUTATIVE ENDONUCLEASE MJ0613 >gi|2826298|gb|AAB98606.1| (U67509)
endonuclease III (nth1) [Methanococcus jannaschii]
Length = 344
Score = 141 bits (353), Expect = 5e-33
Identities = 71/182 (39%), Positives = 114/182 (62%), Gaps = 6/182 (3%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
DP+K LI IIS R +DEVT+ VS++LFK ++ + + E++ + + G +++K
Sbjct: 25 DPFKVLISTIISARTKDEVTEEVSKKLFKEIKDVDDLLNIDEEKLADLI--YPAGFYKNK 82
Query: 93 GKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRIS 152
K + + ++I+ E Y G+VPD EEL+KLPG+GRK AN+V+ F I VDTHV+RI
Sbjct: 83 AKNLKKLAKILKENYNGKVPDSLEELLKLPGVGRKTANLVITLAFNKDGICVDTHVHRIC 142
Query: 153 RRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDEC--PLKEL 210
R + + +PEE E L++ +P++ W +N+ +V G+ +C K +CD+C +KE
Sbjct: 143 NRWEIVDTE-TPEETEFELRKKLPKKYWKVINNLLVVFGREICSS-KSKCDKCFKEIKEK 200
Query: 211 CP 212
CP
Sbjct: 201 CP 202
>pir||E64376 endonuclease III - Methanococcus jannaschii
Length = 353
Score = 141 bits (353), Expect = 5e-33
Identities = 71/182 (39%), Positives = 114/182 (62%), Gaps = 6/182 (3%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
DP+K LI IIS R +DEVT+ VS++LFK ++ + + E++ + + G +++K
Sbjct: 34 DPFKVLISTIISARTKDEVTEEVSKKLFKEIKDVDDLLNIDEEKLADLI--YPAGFYKNK 91
Query: 93 GKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRIS 152
K + + ++I+ E Y G+VPD EEL+KLPG+GRK AN+V+ F I VDTHV+RI
Sbjct: 92 AKNLKKLAKILKENYNGKVPDSLEELLKLPGVGRKTANLVITLAFNKDGICVDTHVHRIC 151
Query: 153 RRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDEC--PLKEL 210
R + + +PEE E L++ +P++ W +N+ +V G+ +C K +CD+C +KE
Sbjct: 152 NRWEIVDTE-TPEETEFELRKKLPKKYWKVINNLLVVFGREICSS-KSKCDKCFKEIKEK 209
Query: 211 CP 212
CP
Sbjct: 210 CP 211
>pir||H83208 endonuclease III PA3495 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9949641|gb|AAG06883.1|AE004770_8
(AE004770) endonuclease III [Pseudomonas aeruginosa]
Length = 212
Score = 138 bits (343), Expect = 8e-32
Identities = 70/187 (37%), Positives = 117/187 (62%), Gaps = 3/187 (1%)
Query: 25 PRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSL 84
PR P++ LI I+S + D ++ + L+ + EAI + VE + ++++
Sbjct: 20 PRTELAYTTPFELLIAVILSAQATDVGVNKATARLYPVANTPEAIHALGVEGLSEYIKT- 78
Query: 85 KVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPV 144
+GL+ SK K ++ET RI++EK+ G+VPD E+L LPG+GRK AN+VL F A+ V
Sbjct: 79 -IGLYNSKAKNVIETCRILIEKHGGQVPDNREDLEALPGVGRKTANVVLNTAFRQLAMAV 137
Query: 145 DTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDE 204
DTH++R++ R G+AP + EVE++L + +PRE + +H ++ HG+ VC+ KP+C
Sbjct: 138 DTHIFRVANRTGIAP-GKNVLEVEKKLLKFVPREYLLDAHHWLILHGRYVCKARKPQCGS 196
Query: 205 CPLKELC 211
C +++LC
Sbjct: 197 CRIEDLC 203
>pir||T36554 probable endonuclease - Streptomyces coelicolor
>gi|5139623|emb|CAB45549.1| (AL079353) putative
endonuclease [Streptomyces coelicolor A3(2)]
Length = 250
Score = 138 bits (343), Expect = 8e-32
Identities = 72/207 (34%), Positives = 117/207 (55%), Gaps = 7/207 (3%)
Query: 12 RALKIVQILKSTYPRERHVSGD---PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEA 68
RA +I + L YP H D P++ ++ ++S + D ++ + LF +YP+ E
Sbjct: 3 RARRINRELAEVYPYA-HPELDFENPFQLVVATVLSAQTTDLRVNQTTPALFAKYPTPED 61
Query: 69 IASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKC 128
+A+A EE++ LR G +R+K K ++ S+ + E + G VP + E+L+KLPG+GRK
Sbjct: 62 LAAAVPEEVEEILRP--TGFFRAKTKSVIGLSKALTEDFGGEVPGRLEDLVKLPGVGRKT 119
Query: 129 ANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMV 188
A +VL FG P I VDTH R+ RR + P+++E + L P+ +W ++H ++
Sbjct: 120 AFVVLGNAFGRPGITVDTHFQRLVRRWRWTE-ETDPDKIEAAVGALFPKSDWTDLSHHVI 178
Query: 189 DHGKSVCRPIKPRCDECPLKELCPRIG 215
HG+ +C KP C CP+ LCP G
Sbjct: 179 WHGRRICHARKPACGACPIAPLCPAYG 205
>pir||C81914 probable endonuclease III NMA0711 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7379435|emb|CAB83997.1| (AL162754) putative
endonuclease III [Neisseria meningitidis Z2491]
Length = 209
Score = 135 bits (337), Expect = 4e-31
Identities = 65/178 (36%), Positives = 111/178 (61%), Gaps = 3/178 (1%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
P++ LI ++S + D ++ + +LF + +A+ ++ + + ++ +GL+++K
Sbjct: 29 PFELLIAVLLSAQATDVGVNKATAKLFPVADTPQAMLDLGLDGVMEYTKT--IGLYKTKS 86
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
K I++T RI+LEKYKG VP+ E L LPG+GRK AN+VL FG P + VDTH++R+S
Sbjct: 87 KHIMQTCRILLEKYKGEVPEDREALESLPGVGRKTANVVLNTAFGHPVMAVDTHIFRVSN 146
Query: 154 RLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
R +AP EVE++L IP+E + +H ++ HG+ C+ +KP+C C + +LC
Sbjct: 147 RTKIAP-GKDVREVEDKLMRFIPKEFLMDAHHWLILHGRYTCKALKPQCQTCIINDLC 203
>sp|O05956|END3_RICPR ENDONUCLEASE III (DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE)
>gi|7437095|pir||F71634 endonuclease III (nth) RP746 -
Rickettsia prowazekii >gi|2073488|emb|CAA72458.1|
(Y11778) endonuclease III [Rickettsia prowazekii]
>gi|3861275|emb|CAA15174.1| (AJ235273) ENDONUCLEASE III
(nth) [Rickettsia prowazekii]
Length = 212
Score = 134 bits (334), Expect = 9e-31
Identities = 68/199 (34%), Positives = 120/199 (60%), Gaps = 5/199 (2%)
Query: 15 KIVQILKSTYPRERH--VSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASA 72
KI +I P+ + + + + L+ I+S R D + ++ LF+ Y + E
Sbjct: 8 KIFEIFSKNNPKPQTELIYKNDFTLLVAVILSARATDISVNLATKHLFETYNTPEKFLEL 67
Query: 73 SVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIV 132
E ++ +++S +GL+ SK K I+ +I+++ Y+ +P+ F+EL+KLPG+GRK AN+V
Sbjct: 68 GEEGLKKYIKS--IGLFNSKAKNIIALCQILIKNYQTSIPNNFKELVKLPGVGRKTANVV 125
Query: 133 LAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGK 192
L F +P + VDTHV+R+S+R+GLA + + VE+ L ++I + Y +H ++ HG+
Sbjct: 126 LNCLFAMPTMAVDTHVFRVSKRIGLAKGNTA-AIVEKELLQIIDEKWLTYAHHWLILHGR 184
Query: 193 SVCRPIKPRCDECPLKELC 211
+C+ KP C+ CP+KE C
Sbjct: 185 YICKARKPGCNICPIKEYC 203
>pir||D81187 endonuclease III NMB0533 [imported] - Neisseria meningitidis (group
B strain MD58) >gi|7225758|gb|AAF40962.1| (AE002409)
endonuclease III [Neisseria meningitidis MC58]
Length = 209
Score = 133 bits (332), Expect = 1e-30
Identities = 64/178 (35%), Positives = 110/178 (60%), Gaps = 3/178 (1%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
P++ LI ++S + D ++ + +LF + +A+ ++ + + ++ +GL+++K
Sbjct: 29 PFELLIAVLLSAQATDVGVNKATAKLFPVADTPQAMLDLGLDGVMEYTKT--IGLYKTKS 86
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
K I++T RI+LEKY G VP+ E L LPG+GRK AN+VL FG P + VDTH++R+S
Sbjct: 87 KHIMQTCRILLEKYNGEVPEDREALESLPGVGRKTANVVLNTAFGHPVMAVDTHIFRVSN 146
Query: 154 RLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
R +AP EVE++L IP+E + +H ++ HG+ C+ +KP+C C + +LC
Sbjct: 147 RTKIAP-GKDVREVEDKLMRFIPKEFLMDAHHWLILHGRYTCKALKPQCQTCIINDLC 203
>gb|AAA86508.1| (U22181) ultraviolet N-glycosylase/AP lyase [Micrococcus luteus]
Length = 268
Score = 132 bits (328), Expect = 4e-30
Identities = 69/203 (33%), Positives = 111/203 (53%), Gaps = 4/203 (1%)
Query: 12 RALKIVQILKSTYPRERHVSG--DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAI 69
RA +I +IL TYP P++ L+ ++S + D + + LF R+P A+
Sbjct: 20 RARRIDRILAETYPYAVAELDFETPFELLVATVLSAQTTDVRVNAATPALFARFPDAHAM 79
Query: 70 ASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCA 129
A+A+ E+Q +RS G +R+K I+ S+ ++ ++ G VP + E+L+ LPG+GRK A
Sbjct: 80 AAATEPELQELVRS--TGFYRNKASAILRLSQELVGRHDGEVPARLEDLVALPGVGRKTA 137
Query: 130 NIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVD 189
+VL FG P I VDTH R++RRLG + R + + P +W ++H ++
Sbjct: 138 FVVLGNAFGQPGITVDTHFGRLARRLGFTDETDPGKGRARRGRPVPPARDWTMLSHRLIF 197
Query: 190 HGKSVCRPIKPRCDECPLKELCP 212
HG+ VC +P C CP+ CP
Sbjct: 198 HGRRVCHARRPACGRCPIARWCP 220
>sp|P46303|UVEN_MICLU ULTRAVIOLET N-GLYCOSYLASE/AP LYASE (UV ENDONUCLEASE) (PYRIMIDINE
DIMER GLYCOSYLASE)
Length = 279
Score = 132 bits (328), Expect = 4e-30
Identities = 69/203 (33%), Positives = 111/203 (53%), Gaps = 4/203 (1%)
Query: 12 RALKIVQILKSTYPRERHVSG--DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAI 69
RA +I +IL TYP P++ L+ ++S + D + + LF R+P A+
Sbjct: 20 RARRIDRILAETYPYAVAELDFETPFELLVATVLSAQTTDVRVNAATPALFARFPDAHAM 79
Query: 70 ASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCA 129
A+A+ E+Q +RS G +R+K I+ S+ ++ ++ G VP + E+L+ LPG+GRK A
Sbjct: 80 AAATEPELQELVRS--TGFYRNKASAILRLSQELVGRHDGEVPARLEDLVALPGVGRKTA 137
Query: 130 NIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVD 189
+VL FG P I VDTH R++RRLG + R + + P +W ++H ++
Sbjct: 138 FVVLGNAFGQPGITVDTHFGRLARRLGFTDETDPGKGRARRGRPVPPARDWTMLSHRLIF 197
Query: 190 HGKSVCRPIKPRCDECPLKELCP 212
HG+ VC +P C CP+ CP
Sbjct: 198 HGRRVCHARRPACGRCPIARWCP 220
>pir||A82252 endonuclease III VC1011 [imported] - Vibrio cholerae (group O1
strain N16961) >gi|9655475|gb|AAF94172.1| (AE004183)
endonuclease III [Vibrio cholerae]
Length = 213
Score = 127 bits (316), Expect = 1e-28
Identities = 66/202 (32%), Positives = 126/202 (61%), Gaps = 5/202 (2%)
Query: 12 RALKIVQILKSTYPR-ERHVS-GDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAI 69
+ ++I++ L++ P+ E ++ P++ LI ++S + D ++ +++L+ + + +
Sbjct: 5 KRIEILERLRAHNPKPETELNWNSPFELLIAVLLSAQATDVSVNKATDKLYAVANTPQTM 64
Query: 70 ASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCA 129
V+ ++ ++++ +GL+ SK + +++T RI+LEK++G VP+ E L LPG+GRK A
Sbjct: 65 LDLGVDGVKEYIKT--IGLFNSKAENVIKTCRILLEKHQGEVPEDREALEALPGVGRKTA 122
Query: 130 NIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVD 189
N+VL FG P I VDTH++R+S R A + +EVE +L +++P E + V+H ++
Sbjct: 123 NVVLNTAFGWPTIAVDTHIFRVSNRTKFAV-GKNVDEVEHKLLKVVPNEFKLDVHHWLIL 181
Query: 190 HGKSVCRPIKPRCDECPLKELC 211
HG+ C KPRC C +++LC
Sbjct: 182 HGRYTCVARKPRCGSCIIEDLC 203
>gi|6679146 thymine glycol DNA glycosylase/AP lyase [Mus musculus]
>gi|2351099|dbj|BAA22080.1| (AB006812) endonuclease III
homologue [Mus musculus] >gi|2407946|emb|CAA70866.1|
(Y09688) endonuclease III homologue 1 [Mus musculus]
>gi|3219302|dbj|BAA28846.1| (AB009371) homologue of
endonuclease III [Mus musculus]
>gi|6688669|emb|CAB65239.1| (AJ001617) Endonuclease III
homologue 1 [Mus musculus]
Length = 300
Score = 125 bits (311), Expect = 4e-28
Identities = 65/180 (36%), Positives = 104/180 (57%), Gaps = 4/180 (2%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
Y+ L+ ++S + +D+VT + L R ++E+I + + + VG WR+K K
Sbjct: 118 YQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVESILQTDDDTLGRLI--YPVGFWRNKVK 175
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTHVYRISR 153
+I +T+ I+ ++Y+G +P EL+ LPG+G K A++ +A +G I I VDTHV+RI+
Sbjct: 176 YIKQTTAILQQRYEGDIPASVAELVALPGVGPKMAHLAMAVAWGTISGIAVDTHVHRIAN 235
Query: 154 RL-GLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCP 212
RL +PEE + L+E +PR W VN +V G+ +C P+ PRC C K LCP
Sbjct: 236 RLRWTKKMTKTPEETRKNLEEWLPRVLWSEVNGLLVGFGQQICLPVHPRCQACLNKALCP 295
>sp|P20625|END3_ECOLI ENDONUCLEASE III (DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE)
>gi|78420|pir||A32412 DNA-(apurinic or apyrimidinic
site) lyase (EC 4.2.99.18) endonuclease III [validated]
- Escherichia coli >gi|1311214|pdb|2ABK| Refinement Of
The Native Structure Of Endonuclease Iii To A Resolution
Of 1.85 Angstrom >gi|146972|gb|AAA24227.1| (J02857)
endonuclease III [Escherichia coli]
>gi|1742691|dbj|BAA15387.1| (D90806) Deoxyribonuclease
(pyrimidine dimer) (EC 3.1.25.1) [Escherichia coli]
>gi|1742699|dbj|BAA15394.1| (D90807) Deoxyribonuclease
(pyrimidine dimer) (EC 3.1.25.1) [Escherichia coli]
>gi|1742723|dbj|BAA15417.1| (D90808) Deoxyribonuclease
(pyrimidine dimer) (EC 3.1.25.1) [Escherichia coli]
>gi|1787920|gb|AAC74705.1| (AE000258) endonuclease III;
specific for apurinic and/or apyrimidinic sites
[Escherichia coli K12]
Length = 211
Score = 125 bits (310), Expect = 6e-28
Identities = 63/178 (35%), Positives = 109/178 (60%), Gaps = 3/178 (1%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
P++ LI ++S + D ++ + +L+ + A+ VE ++ ++++ +GL+ SK
Sbjct: 29 PFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKT--IGLYNSKA 86
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
+ I++T RI+LE++ G VP+ L LPG+GRK AN+VL FG P I VDTH++R+
Sbjct: 87 ENIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCN 146
Query: 154 RLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
R AP + E+VEE+L +++P E + +H ++ HG+ C KPRC C +++LC
Sbjct: 147 RTQFAP-GKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLC 203
>sp|P44319|END3_HAEIN ENDONUCLEASE III (DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE)
>gi|1074056|pir||G64136 probable DNA-(apurinic or
apyrimidinic site) lyase (EC 4.2.99.18) - Haemophilus
influenzae (strain Rd KW20) >gi|1574542|gb|AAC23335.1|
(U32842) endonuclease III (nth) [Haemophilus influenzae
Rd]
Length = 211
Score = 125 bits (310), Expect = 6e-28
Identities = 64/191 (33%), Positives = 114/191 (59%), Gaps = 3/191 (1%)
Query: 21 KSTYPRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNF 80
++ +P P++ LI I+S + D+ ++ +E+LF + +AI ++ ++++
Sbjct: 16 QNPHPTTELQYNSPFELLIAVILSAQATDKGVNKATEKLFPVANTPQAILDLGLDGLKSY 75
Query: 81 LRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIP 140
+++ +GL+ SK + I++T R ++EK+ G VP+ E L L G+GRK AN+VL FG P
Sbjct: 76 IKT--IGLFNSKAENIIKTCRDLIEKHNGEVPENREALEALAGVGRKTANVVLNTAFGHP 133
Query: 141 AIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKP 200
I VDTH++R+ R A +VEE+L +++P E + V+H ++ HG+ C KP
Sbjct: 134 TIAVDTHIFRVCNRTNFAA-GKDVVKVEEKLLKVVPNEFKVDVHHWLILHGRYTCIARKP 192
Query: 201 RCDECPLKELC 211
RC C +++LC
Sbjct: 193 RCGSCIIEDLC 203
>sp|O69642|END3_MYCTU ENDONUCLEASE III (DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE)
>gi|7437098|pir||C70790 probable Endonuclease III -
Mycobacterium tuberculosis (strain H37RV)
>gi|2960098|emb|CAA17996.1| (AL022121) nth
[Mycobacterium tuberculosis]
Length = 226
Score = 124 bits (309), Expect = 7e-28
Identities = 62/183 (33%), Positives = 104/183 (55%), Gaps = 3/183 (1%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
P + + I+S ++ D+ + + LF RY + A A E+++ +R G +R+K
Sbjct: 21 PLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADRTELESLIRP--TGFYRNKA 78
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
++ + ++E++ G VP ++L+ LPG+GRK AN++L FGIP I VDTH R+ R
Sbjct: 79 ASLIGLGQALVERFGGEVPATMDKLVTLPGVGRKTANVILGNAFGIPGITVDTHFGRLVR 138
Query: 154 RLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCPR 213
R + P +VE+ + ELI R+EW ++H ++ HG+ VC +P C C L + CP
Sbjct: 139 RWRWTTAE-DPVKVEQAVGELIERKEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPS 197
Query: 214 IGV 216
G+
Sbjct: 198 FGL 200
>pir||A64593 endonuclease III - Helicobacter pylori (strain 26695)
>gi|2313704|gb|AAD07651.1| (AE000572) endonuclease III
(nth) [Helicobacter pylori 26695]
Length = 218
Score = 123 bits (307), Expect = 1e-27
Identities = 68/205 (33%), Positives = 122/205 (59%), Gaps = 10/205 (4%)
Query: 11 ERALKIVQILKSTYPRE----RHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSI 66
++A +I ++L YP + RH + PY+ L+ I+S + D ++++ +LF++YPS+
Sbjct: 12 QKAQQIKELLLKHYPNQTTELRHKN--PYELLVATILSAQCTDARVNQITPKLFEKYPSV 69
Query: 67 EAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGR 126
+A AS+EE++ ++S V + +K K ++ ++ ++ +KG +P +EL+ L G+G+
Sbjct: 70 NDLALASLEEVKEIIKS--VSYFNNKSKHLISMAQKVVRDFKGVIPSTQKELMSLDGVGQ 127
Query: 127 KCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHA 186
K AN+VL+ F I VDTHV+R + RLGL+ P + EE L +L ++ ++HA
Sbjct: 128 KTANVVLSVCFDANCIAVDTHVFRATHRLGLSN-AKDPIKTEEELSDLF-KDNLSKLHHA 185
Query: 187 MVDHGKSVCRPIKPRCDECPLKELC 211
++ G+ C+ P C C LKE C
Sbjct: 186 LILFGRYTCKAKNPLCGACFLKEFC 210
>pir||B71919 endonuclease III - Helicobacter pylori (strain J99)
>gi|4155080|gb|AAD06115.1| (AE001486) ENDONUCLEASE III
[Helicobacter pylori J99]
Length = 214
Score = 123 bits (306), Expect = 2e-27
Identities = 68/206 (33%), Positives = 123/206 (59%), Gaps = 10/206 (4%)
Query: 10 RERALKIVQILKSTYPRE----RHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPS 65
+ +A +I ++L YP + RH + PY+ L+ I+S + D ++++ +LF++YPS
Sbjct: 7 KTKAQQIKELLLKHYPNQTTELRHKN--PYELLVATILSAQCTDARVNQITPKLFEKYPS 64
Query: 66 IEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIG 125
+ +A AS+EE++ ++S+ +K K ++ +++ +KG +P +EL+ L G+G
Sbjct: 65 VNDLALASLEEVKEIIQSVSYS--NNKSKHLISMGAKVVKDFKGVIPSTQKELMSLDGVG 122
Query: 126 RKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNH 185
+K AN+VL+ F I VDTHV+R + RLGL+ + +P + EE L +L ++ ++H
Sbjct: 123 QKTANVVLSVCFDANYIAVDTHVFRTTHRLGLSNAN-TPIKTEEELSDLF-KDNLSKLHH 180
Query: 186 AMVDHGKSVCRPIKPRCDECPLKELC 211
A++ G+ C+ P CD C LKE C
Sbjct: 181 ALILFGRYTCKAKNPLCDACFLKEFC 206
>emb|CAA70865.1| (Y09687) endonuclease III homologue 1 [Homo sapiens]
Length = 303
Score = 120 bits (299), Expect = 1e-26
Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 4/180 (2%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
Y+ L+ ++S + +D+VT + L R ++++I + + VG WRSK K
Sbjct: 121 YQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLI--YPVGFWRSKVK 178
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTHVYRISR 153
+I +TS I+ + Y G +P EL+ LPG+G K A++ +A +G + I VDTHV+RI+
Sbjct: 179 YIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIAN 238
Query: 154 RL-GLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCP 212
RL SPEE L+E +PRE W +N +V G+ C P+ PRC C + LCP
Sbjct: 239 RLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHACLNQALCP 298
>gi|4505471 nth (E.coli endonuclease III)-like 1 [Homo sapiens]
>gi|11431131|ref|XP_007930.1| nth (E.coli endonuclease
III)-like 1 [Homo sapiens] >gi|3522921|gb|AAC34209.1|
(AC005600) hNTH1 [Homo sapiens]
Length = 312
Score = 120 bits (299), Expect = 1e-26
Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 4/180 (2%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
Y+ L+ ++S + +D+VT + L R ++++I + + VG WRSK K
Sbjct: 130 YQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLI--YPVGFWRSKVK 187
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTHVYRISR 153
+I +TS I+ + Y G +P EL+ LPG+G K A++ +A +G + I VDTHV+RI+
Sbjct: 188 YIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIAN 247
Query: 154 RL-GLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCP 212
RL SPEE L+E +PRE W +N +V G+ C P+ PRC C + LCP
Sbjct: 248 RLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHACLNQALCP 307
>gb|AAK40470.1| DNA endonuclease III, probable (ntH-1) [Sulfolobus solfataricus]
Length = 236
Score = 120 bits (299), Expect = 1e-26
Identities = 67/189 (35%), Positives = 113/189 (59%), Gaps = 12/189 (6%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYP-SIEAIASASVEEMQNFLRSLKVGLWRS 91
D +K L+ I+SQ + D+ + EL ++ + E +++A++ ++++ L+ GL+R+
Sbjct: 34 DCFKVLVATILSQNSTDKSAIKAYLELERKVGVTPEKLSNANLADIESALKIS--GLYRT 91
Query: 92 KGKWIVETSRIILEKYKGRVPDKF------EELIKLPGIGRKCANIVL--AYGF-GIPAI 142
K K + E SRIILE+Y G + +EL+KL GIG K A++VL YG+ G
Sbjct: 92 KAKRLKEISRIILERYNGLIDSLLNTSNARDELLKLEGIGEKTADVVLLTCYGYYGYKVF 151
Query: 143 PVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRC 202
PVDTH+ R+S+RLG+ P +A + LKEL + ++++H ++ HG+ C+ KP C
Sbjct: 152 PVDTHITRVSKRLGIVPTNAKYSLISSTLKELFSAYDLLHLHHMLIAHGRQTCKARKPLC 211
Query: 203 DECPLKELC 211
+ C +KE C
Sbjct: 212 NSCIIKECC 220
>pir||S75373 probable DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) -
Sulfolobus solfataricus >gi|1707778|emb|CAA69576.1|
(Y08257) endonuclease III [Sulfolobus solfataricus]
Length = 236
Score = 120 bits (299), Expect = 1e-26
Identities = 67/189 (35%), Positives = 113/189 (59%), Gaps = 12/189 (6%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYP-SIEAIASASVEEMQNFLRSLKVGLWRS 91
D +K L+ I+SQ + D+ + EL ++ + E +++A++ ++++ L+ GL+R+
Sbjct: 34 DCFKVLVATILSQNSTDKSAIKAYLELERKVGVTPEKLSNANLADIESALKIS--GLYRT 91
Query: 92 KGKWIVETSRIILEKYKGRVPDKF------EELIKLPGIGRKCANIVL--AYGF-GIPAI 142
K K + E SRIILE+Y G + +EL+KL GIG K A++VL YG+ G
Sbjct: 92 KAKRLKEISRIILERYNGLIDSLLNTSNARDELLKLEGIGEKTADVVLLTCYGYYGYKVF 151
Query: 143 PVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRC 202
PVDTH+ R+S+RLG+ P +A + LKEL + ++++H ++ HG+ C+ KP C
Sbjct: 152 PVDTHITRVSKRLGIVPTNAKYSLISSTLKELFSAYDLLHLHHMLIAHGRQTCKARKPLC 211
Query: 203 DECPLKELC 211
+ C +KE C
Sbjct: 212 NSCIIKECC 220
>gb|AAC51136.1| (U81285) endonuclease III [Homo sapiens]
>gi|1881376|dbj|BAA19413.1| (AB001575) endonuclease III
homolog [Homo sapiens] >gi|3550834|dbj|BAA32695.1|
(AB014460) similar to E.coli endonuclease III [Homo
sapiens]
Length = 304
Score = 120 bits (299), Expect = 1e-26
Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 4/180 (2%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
Y+ L+ ++S + +D+VT + L R ++++I + + VG WRSK K
Sbjct: 122 YQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLI--YPVGFWRSKVK 179
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTHVYRISR 153
+I +TS I+ + Y G +P EL+ LPG+G K A++ +A +G + I VDTHV+RI+
Sbjct: 180 YIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIAN 239
Query: 154 RL-GLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCP 212
RL SPEE L+E +PRE W +N +V G+ C P+ PRC C + LCP
Sbjct: 240 RLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHACLNQALCP 299
>gb|AAB41534.1| (U79718) endonuclease III homolog 1, hNTH1 [Homo sapiens]
Length = 312
Score = 120 bits (298), Expect = 1e-26
Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 4/180 (2%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
Y+ L+ ++S + +D+VT + L R ++++I + + VG WRSK K
Sbjct: 130 YQVLLSLMLSSQTKDQVTAGAIQRLRARGLAVDSILQTDDATLGKLI--YPVGFWRSKVK 187
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTHVYRISR 153
+I +TS I+ + Y G +P EL+ LPG+G K A++ +A +G + I VDTHV+RI+
Sbjct: 188 YIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIAN 247
Query: 154 RL-GLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCP 212
RL SPEE L+E +PRE W +N +V G+ C P+ PRC C + LCP
Sbjct: 248 RLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHACLNQALCP 307
>gb|AAG28772.1|AF300990_1 (AF300990) endonuclease III [Salmonella typhimurium]
Length = 181
Score = 120 bits (297), Expect = 2e-26
Identities = 60/177 (33%), Positives = 108/177 (60%), Gaps = 3/177 (1%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
P++ LI ++S + D ++ + +L+ + A+ VE +++++++ +GL+ SK
Sbjct: 8 PFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKSYIKT--IGLFNSKA 65
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
+ +++T I+L+K+ G VP+ L LPG+GRK AN+VL FG P I VDTH++R+
Sbjct: 66 ENVIKTCHILLDKHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCN 125
Query: 154 RLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKEL 210
R AP + E+VEE+L +++P E + +H ++ HG+ C KPRC C +++L
Sbjct: 126 RTQFAP-GKNVEQVEEKLLKVVPNEFKVDCHHWLILHGRYTCIARKPRCGSCLIEDL 181
>gb|AAF53949.1| (AE003668) CG9272 gene product [Drosophila melanogaster]
Length = 308
Score = 118 bits (294), Expect = 4e-26
Identities = 60/180 (33%), Positives = 100/180 (55%), Gaps = 4/180 (2%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
++ L+ ++S + +D+ T L R + + V E++N L V +++K K
Sbjct: 117 FQNLVALMLSSQTKDQTTYEAMNRLKDRGLTPLKVKEMPVTELENLLHP--VSFYKNKAK 174
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTHVYRISR 153
++ +T I+ +KY +PD ++L+ LPG+G K A+I +A + I I VD HV+R+S
Sbjct: 175 YLKQTVEILTDKYGSDIPDNVKDLVALPGVGPKMAHICMAVAWNKITGIGVDVHVHRLSN 234
Query: 154 RLGLAPWDAS-PEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCP 212
RLG P PE+ L++ +P W VNH V G+++C P+KP C EC K++CP
Sbjct: 235 RLGWVPKPTKEPEQTRVALEKWLPFSLWSEVNHLFVGFGQTICTPVKPNCGECLNKDICP 294
>sp|P54137|END3_CAEEL PROBABLE ENDONUCLEASE III HOMOLOG (DNA-(APURINIC OR APYRIMIDINIC
SITE) LYASE) >gi|7506576|pir||T24131 hypothetical
protein R10E4.5 - Caenorhabditis elegans
>gi|3879052|emb|CAA90766.1| (Z50874) contains similarity
to Pfam domain: PF00730 (Endonuclease III), Score=369.5,
E-value=1.1e-107, N=1 [Caenorhabditis elegans]
Length = 259
Score = 118 bits (293), Expect = 5e-26
Identities = 60/179 (33%), Positives = 103/179 (57%), Gaps = 4/179 (2%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
++ L+ ++S + RDEV + L SI I V +++ L VG ++ K
Sbjct: 29 FQVLVALMLSSQTRDEVNAAAMKRLKDHGLSIGKILEFKVPDLETIL--CPVGFYKRKAV 86
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTHVYRISR 153
++ +T++I+ + + G +PD + L LPG+G K AN+V+ +G I VDTHV+RIS
Sbjct: 87 YLQKTAKILKDDFSGDIPDSLDGLCALPGVGPKMANLVMQIAWGECVGIAVDTHVHRISN 146
Query: 154 RLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCP 212
RLG ++PE+ ++ L+ L+P+ EW +NH +V G+ C+P++P+C C + CP
Sbjct: 147 RLGWIK-TSTPEKTQKALEILLPKSEWQPINHLLVGFGQMQCQPVRPKCGTCLCRFTCP 204
>pir||H70192 endonuclease III (nth) homolog - Lyme disease spirochete
>gi|2688678|gb|AAC67089.1| (AE001174) endonuclease III
(nth) [Borrelia burgdorferi]
Length = 222
Score = 118 bits (292), Expect = 7e-26
Identities = 65/180 (36%), Positives = 104/180 (57%), Gaps = 3/180 (1%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
Y+ LI I+S R D + +++S LF+RY + E+++ A+V +++ + K G + K K
Sbjct: 45 YELLIMVILSARTTDNLVNKISPYLFERYENFESLSRANVRDVEKLI--YKTGFYSRKAK 102
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRR 154
IV S ILEK+ G +P+ +LIKLPG+GRK AN++L + PAI VDTH R+ R
Sbjct: 103 NIVNCSIDILEKFNGVIPNNIFDLIKLPGVGRKTANVILGSVYNKPAIIVDTHFSRVITR 162
Query: 155 LGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCPRI 214
L+ ++SP ++E LK I + + A+ H + +C CD C L++ PR+
Sbjct: 163 HALS-LESSPIKIELDLKRRIKPCKQYRFSMAINKHAREICTSRNVNCDNCFLEKFAPRV 221
>pir||E82780 endonuclease III XF0647 [imported] - Xylella fastidiosa (strain
9a5c) >gi|9105523|gb|AAF83457.1|AE003909_10 (AE003909)
endonuclease III [Xylella fastidiosa]
Length = 218
Score = 116 bits (288), Expect = 2e-25
Identities = 62/178 (34%), Positives = 104/178 (57%), Gaps = 3/178 (1%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
P++ LI I+S + D ++ + L+ + +AI + ++ + + +GL+ +K
Sbjct: 35 PFELLIAVILSAQATDIGVNKATRRLYSLANTPQAILDLGEDALKRHIST--IGLFNAKA 92
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
K ++ T RI++E+Y G VP L LPG+GRK AN+VL FG P I VDTH++R++
Sbjct: 93 KNVIATCRILVEQYGGAVPRDRAMLEALPGVGRKTANVVLNTAFGEPTIAVDTHIFRVAN 152
Query: 154 RLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
R GLA ++ VE+ L + IP+E +H ++ HG+ VC+ KP C +C + +LC
Sbjct: 153 RTGLA-IGSNVRVVEDALLKRIPQEFLKDAHHWLILHGRYVCKARKPNCSQCVIADLC 209
>gb|AAG19103.1| (AE005008) endonuclease III; NthA2 [Halobacterium sp. NRC-1]
Length = 227
Score = 114 bits (283), Expect = 8e-25
Identities = 63/176 (35%), Positives = 94/176 (52%), Gaps = 4/176 (2%)
Query: 38 LIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIV 97
L+ I+S + DE + +E LF Y ++ A+A E + L S+ + SK +I
Sbjct: 39 LVAVILSAQCTDERVNAETEHLFDTYETVADYANADEEALAAELNSITY--YNSKAGYIK 96
Query: 98 ETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIP-AIPVDTHVYRISRRLG 156
++ ILE + G VPD +L L G+GRK AN+VL +G + I VDTHV R+SRRLG
Sbjct: 97 SAAQSILEDHDGAVPDTMSDLTDLSGVGRKTANVVLQHGHDLTQGIVVDTHVQRLSRRLG 156
Query: 157 LAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELCP 212
+ PE +E L ++P + W H ++ HG+ C P C C L ++CP
Sbjct: 157 ITE-KKRPEAIETDLMPVVPEDHWKNYTHWLIAHGRETCTARNPDCGACVLADICP 211
>gb|AAD26474.1|AC007169_6 (AC007169) putative endonuclease [Arabidopsis thaliana]
Length = 281
Score = 114 bits (282), Expect = 1e-24
Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 10/186 (5%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKR-YPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
+ L+ ++S + +D+V + L + + EA+ A ++ + VG + K
Sbjct: 76 FAVLLGALLSSQTKDQVNNAAIHRLHQNGLLTPEAVDKADESTIKELI--YPVGFYTRKA 133
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTHVYRIS 152
++ + +RI L KY G +P ++L+ LPGIG K A+++L + + I VDTHV+RI
Sbjct: 134 TYMKKIARICLVKYDGDIPSSLDDLLSLPGIGPKMAHLILHIAWNDVQGICVDTHVHRIC 193
Query: 153 RRLGLAPWDA------SPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECP 206
RLG SPEE L++ +P+EEW+ +N +V G+ +C PI+PRC+ C
Sbjct: 194 NRLGWVSRPGTKQKTTSPEETRVALQQWLPKEEWVAINPLLVGFGQMICTPIRPRCEACS 253
Query: 207 LKELCP 212
+ +LCP
Sbjct: 254 VSKLCP 259
>emb|CAC16135.1| (AJ272248) endonuclease III homologue [Arabidopsis thaliana]
Length = 354
Score = 113 bits (280), Expect = 2e-24
Identities = 59/186 (31%), Positives = 102/186 (54%), Gaps = 10/186 (5%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKR-YPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
+ L+ ++S + +D+V + L + + EA+ A ++ + VG + K
Sbjct: 149 FAVLLGALLSSQTKDQVNNAAIHRLHQNGLLTPEAVDKADESTIKELI--YPVGFYTRKA 206
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTHVYRIS 152
++ + +RI L KY G +P ++L+ LPGIG K A+++L + + I VDTHV+RI
Sbjct: 207 TYMKKIARICLVKYDGDIPSSLDDLLSLPGIGPKMAHLILHIAWNDVQGICVDTHVHRIC 266
Query: 153 RRLGLAPWDA------SPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECP 206
RLG SPEE L++ +P+EEW+ +N +V G+ +C P++PRC+ C
Sbjct: 267 NRLGWVSRPGTKQKTTSPEETRVALQQWLPKEEWVAINPLLVGFGQMICTPLRPRCEACS 326
Query: 207 LKELCP 212
+ +LCP
Sbjct: 327 VSKLCP 332
>sp|O83754|END3_TREPA ENDONUCLEASE III (DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE)
>gi|7437096|pir||H71281 probable endonuclease III (nth)
- syphilis spirochete >gi|3323085|gb|AAC65744.1|
(AE001249) endonuclease III (nth) [Treponema pallidum]
Length = 211
Score = 112 bits (277), Expect = 4e-24
Identities = 58/177 (32%), Positives = 103/177 (57%), Gaps = 3/177 (1%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
+ L+ ++S + D+ ++ + LF + +A+ + E + +++R+ + L+ +K +
Sbjct: 33 FTLLVAVLLSAQATDKSVNKATAALFDVADTPQAMLALGEERLCSYIRT--INLYPTKAR 90
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRR 154
I+ S ++E++ +VP L LPG+G K AN+VL GFGIP I VDTH+ R + R
Sbjct: 91 RIIALSAELIERFAAQVPCDAHALESLPGVGHKTANVVLNMGFGIPTIAVDTHILRTAPR 150
Query: 155 LGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
+GL+ +P VE L + PRE ++ +H ++ HG+ C +PRC EC L++LC
Sbjct: 151 IGLSS-GRTPRAVERDLLVVTPREFRMHAHHWILLHGRYTCTARRPRCTECCLRDLC 206
>pir||B81407 endonuclease III Cj0595c [imported] - Campylobacter jejuni (strain
NCTC 11168) >gi|6968062|emb|CAB75231.1| (AL139075)
endonuclease III [Campylobacter jejuni]
Length = 208
Score = 104 bits (258), Expect = 7e-22
Identities = 55/177 (31%), Positives = 104/177 (58%), Gaps = 4/177 (2%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
Y+ L+ ++S + D+ + ++ +LFK YP I+++A+A++ ++ ++++ + +K +
Sbjct: 28 YELLVCVMLSAQCTDKRVNLITPDLFKAYPDIKSLANANLSSLKTYIQTCS--FFNNKAQ 85
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRR 154
+++ ++ + E + G +P + L L G+G+K A++VL G + VDTHV+R+S R
Sbjct: 86 NLIKMAKAVCENFDGEIPLDEQNLKSLAGVGQKTAHVVLIEWCGANFMAVDTHVFRVSHR 145
Query: 155 LGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
LGL+ +PE EE L ++ Y++ AMV G+ C+ KP C EC L LC
Sbjct: 146 LGLSK-AKTPEATEEDLTRTF-KDNLNYLHQAMVLFGRYTCKAKKPLCKECFLNHLC 200
>gb|AAF29397.1|AC009999_17 (AC009999) Contains similarity to an endonuclease III homolog from
Homo sapiens gb|U81285, and contains an Endonuclease III
PF|00730 domain. [Arabidopsis thaliana]
Length = 402
Score = 104 bits (257), Expect = 9e-22
Identities = 63/212 (29%), Positives = 105/212 (48%), Gaps = 31/212 (14%)
Query: 25 PRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKR-YPSIEAIASASVEEMQNFLRS 83
P+ER + LI ++S + ++ +T E L + + EAI A ++ +
Sbjct: 176 PKERR-----FYVLIGTLLSSQTKEHITGAAVERLHQNGLLTPEAIDKADESTIKELI-- 228
Query: 84 LKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAI 142
VG + K + + ++I L +Y G +P EEL+ LPG+G K A++VL + + I
Sbjct: 229 YPVGFYTRKATNVKKVAKICLMEYDGDIPRTLEELLSLPGVGPKIAHLVLHVAWNDVQGI 288
Query: 143 PVDTHVYRISRRLG----------------------LAPWDASPEEVEERLKELIPREEW 180
VDTHV+RI RLG L +SPEE L++ +P+ EW
Sbjct: 289 CVDTHVHRICNRLGWVSKPGTKQFAYLLLVTYLYFVLDQKTSSPEETRVALQQWLPKGEW 348
Query: 181 IYVNHAMVDHGKSVCRPIKPRCDECPLKELCP 212
+ +N +V G+++C P++P C C + E+CP
Sbjct: 349 VAINFLLVGFGQTICTPLRPHCGTCSITEICP 380
>sp|P57219|END3_BUCAI ENDONUCLEASE III (DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE)
>gi|10038802|dbj|BAB12837.1| (AP001118) endonuclease III
[Buchnera sp. APS]
Length = 210
Score = 103 bits (254), Expect = 2e-21
Identities = 66/205 (32%), Positives = 113/205 (54%), Gaps = 7/205 (3%)
Query: 10 RERALKIVQILKSTYPR---ERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSI 66
+++ +I+ IL P E S D ++ L+ I+S ++ D + ++ ++ LFK +
Sbjct: 3 KKKRYEILSILSRNNPEPKIELFFSSD-FELLLSVILSAQSTDFIVNKTTKILFKIANTP 61
Query: 67 EAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGR 126
E I +E ++N+++ +GL+ +K I+ TS IIL KY VP+ EL LPG+GR
Sbjct: 62 ETIFLLGLERLKNYIKD--IGLYNTKALNIIRTSFIILTKYNSIVPNNRIELESLPGVGR 119
Query: 127 KCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHA 186
K ANI+L F I VDTHV+R+ R A + + VEE+L +++P + +
Sbjct: 120 KTANIILNILFKKKTIAVDTHVFRVCNRTNFAK-GKNVKIVEEKLIKVVPSIFKLNFHSW 178
Query: 187 MVDHGKSVCRPIKPRCDECPLKELC 211
+ HG+ +C K +C+ C + +LC
Sbjct: 179 FILHGRYICTARKIKCNICLIFKLC 203
>gb|AAG18952.1| (AE004996) endonuclease III; NthA1 [Halobacterium sp. NRC-1]
Length = 265
Score = 97.9 bits (240), Expect = 9e-20
Identities = 68/233 (29%), Positives = 114/233 (48%), Gaps = 19/233 (8%)
Query: 5 SSLSERERALKIVQILKSTYPRERHVSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRY- 63
+S ++ +A +V L Y ++ + ++ L+R ++SQ D+ + + L +RY
Sbjct: 21 ASGADPTQAALVVDRLGELYWQKTYGGRAAFECLVRTVLSQNTSDKASQPAHDALMQRYG 80
Query: 64 PSIEAIASASVEEMQNFLRSL--KVGLWRSKGKWIVETSRIILEKYKGRV---------- 111
+ + +A+A + Q+ L GL+ K I+ + + E+Y G
Sbjct: 81 AAADDLAAALADADQDVLADTISMAGLYNQKSATIIRIADRVCEEYGGADGFDAFVREGD 140
Query: 112 PDKFEE-LIKLPGIGRKCANIVLAYGFGIPAI-PVDTHVYRISRRLGLAPWDASPEEVEE 169
PD L+ + G+G K A+ VL + G P + PVDTHV+RI+RR+G+AP A E V
Sbjct: 141 PDAVRAALLDMTGVGPKTADCVLLFAGGAPGVFPVDTHVHRIARRMGIAPAAADHEAVRA 200
Query: 170 RLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDE----CPLKELCPRIGVQA 218
L+ +P + + AM+ G+ C P C + CPL E C R+GV A
Sbjct: 201 ALEAAVPDAACGFGHTAMIQFGREYCTARDPACLDDPAACPLAEHCDRVGVDA 253
>gb|AAF35322.1|AF222908_2 (AF222908) Ntg1 [Candida albicans]
Length = 311
Score = 96.7 bits (237), Expect = 2e-19
Identities = 57/182 (31%), Positives = 100/182 (54%), Gaps = 11/182 (6%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEEL----FKRYPS---IEAIASASVEEMQNFLRSLKVG 87
++ LI ++S + +DEV + L K +P IE++ S E+ +++ KVG
Sbjct: 100 FQLLISLMLSSQTKDEVNYEAMKNLHNGLLKVHPDGLCIESVLKLSESEIDAYIK--KVG 157
Query: 88 LWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPA-IPVDT 146
K ++I +T I++E + G +P EE++ LPG+G K ++L G+GI A I VD
Sbjct: 158 FHNRKAQYIRKTCSILMENHDGDIPKTIEEIVALPGVGPKMGFLLLQSGWGINAGIGVDV 217
Query: 147 HVYRISRRLG-LAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDEC 205
H++R++ G ++P +PE+ L+E +P++ W +N +V G+ +C P CD C
Sbjct: 218 HLHRLALMWGWVSPKANTPEKARIELQEWLPKDYWTDINPLVVGFGQVICVPRAANCDIC 277
Query: 206 PL 207
L
Sbjct: 278 TL 279
>pir||A72682 probable A/G-specific adenine glycosylase APE0875 - Aeropyrum
pernix (strain K1) >gi|5104542|dbj|BAA79857.1|
(AP000060) 286aa long hypothetical A/G-specific adenine
glycosylase [Aeropyrum pernix]
Length = 286
Score = 94.8 bits (232), Expect = 8e-19
Identities = 56/187 (29%), Positives = 100/187 (52%), Gaps = 8/187 (4%)
Query: 31 SGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWR 90
+ DP+ L+ + ++ RV EE +RYP+ +A+ASA +E++ +R L G+
Sbjct: 96 TADPWAILVAAFLLRKTTARQVVRVYEEFLRRYPNPKALASAREDEVRELIRPL--GIEH 153
Query: 91 SKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYR 150
+ K ++E ++ I +Y GR+P E+L +LPG+G A+ VL G P +D ++ R
Sbjct: 154 QRAKHLIELAKHIEARYGGRIPCSKEKLKELPGVGDYIASEVLLAACGSPEPLLDRNMIR 213
Query: 151 ISRR-LGLAPWDASPE---EVEERLKELIPREEWI--YVNHAMVDHGKSVCRPIKPRCDE 204
I R LG+ P ++ + ++P++ + N+ M+D + +C KP C E
Sbjct: 214 ILERVLGVKSAKKRPHTDPKMWSTARRIVPKDPDMAKEFNYGMLDLARKICTARKPLCTE 273
Query: 205 CPLKELC 211
CPL ++C
Sbjct: 274 CPLNDIC 280
>pir||C75459 probable endonuclease III - Deinococcus radiodurans (strain R1)
>gi|6458651|gb|AAF10505.1|AE001945_9 (AE001945)
endonuclease III, putative [Deinococcus radiodurans]
Length = 338
Score = 92.8 bits (227), Expect = 3e-18
Identities = 65/200 (32%), Positives = 95/200 (47%), Gaps = 16/200 (8%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
DP LIR I+SQ+N V R E L YP EA + ++ L+S GL R K
Sbjct: 123 DPLGGLIRTILSQQNTRRVAQRQWEVLTATYPQWEAALLDGPDGIEATLKSAGGGLSRMK 182
Query: 93 GKWIVETSRIILEKYKG----------RVPDKFEE----LIKLPGIGRKCANIVLAYGFG 138
+I + E + G P+ E+ L LPG+G K +VL +
Sbjct: 183 ADYIYGILAHLQEHHGGLSLRFLREFPHTPEGHEQARQALAALPGVGHKTVALVLLFDLR 242
Query: 139 IPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPRE-EWIYVNH-AMVDHGKSVCR 196
PA+PVD ++ R ++RL L P + +VE E++P + E + H + V HG+ CR
Sbjct: 243 RPAMPVDGNMERAAKRLELVPAAWNSHKVERWYAEVMPADWETRFALHISGVRHGRDTCR 302
Query: 197 PIKPRCDECPLKELCPRIGV 216
P C +CPL+E CP +
Sbjct: 303 SKHPLCPQCPLREFCPSASI 322
>gb|AAF37269.1|AF222334_1 (AF222334) putative DNA glycosylase [Pyrobaculum aerophilum]
Length = 223
Score = 92.8 bits (227), Expect = 3e-18
Identities = 51/189 (26%), Positives = 100/189 (51%), Gaps = 19/189 (10%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSI--EAIASASVEEMQNFLRSLKVGLWRSK 92
+K L+ ++SQ D+ + E L K+ +I +A+ +E ++ ++ G++R +
Sbjct: 32 FKMLVAVVLSQNTSDKNAFKALENLEKQVGTITPQALLELPIEALEELIKP--AGMYRQR 89
Query: 93 GKWIVETSRIILEKYKGRVPDKFEE---------LIKLPGIGRKCANIVLAYGFGIPAIP 143
+ + + ++ G P++ E L+ LPG+G+K A++VL G+PA P
Sbjct: 90 ARNLKALAEAFIQL--GLTPERLVEMGPERARELLLSLPGVGKKTADVVLV-NLGLPAFP 146
Query: 144 VDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCD 203
VDTH+ RI++R G+ +E+ E +PR++++ + ++ G+ VCR P+C
Sbjct: 147 VDTHITRIAKRWGIGE---KYDEISRWFMERLPRDKYLDFHLKLIQFGRDVCRARNPKCG 203
Query: 204 ECPLKELCP 212
+CP+ CP
Sbjct: 204 QCPIGAKCP 212
>pir||D72029 endonuclease III CP1032 [imported] - Chlamydophila pneumoniae
(strains CWL029 and AR39) >gi|4377151|gb|AAD18975.1|
(AE001664) Enodnuclease III [Chlamydophila pneumoniae
CWL029] >gi|7189945|gb|AAF38807.1| (AE002260)
endonuclease III [Chlamydophila pneumoniae AR39]
>gi|8979211|dbj|BAA99045.1| (AP002548) enodnuclease III
[Chlamydophila pneumoniae J138]
Length = 209
Score = 91.3 bits (223), Expect = 9e-18
Identities = 53/210 (25%), Positives = 105/210 (49%), Gaps = 9/210 (4%)
Query: 16 IVQILKSTYPRER-HVSG--DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASA 72
I++ L + +P + + G P++ LI ++S + D+ + V+ +LF + P ++I
Sbjct: 5 ILRTLNALFPNPKPSLEGWSSPFQLLIAILLSGNSTDKAVNSVTPQLFAKAPDAQSILDL 64
Query: 73 SVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIV 132
++ + GL K +I + S+I++ + G P+ L +LPG+GRK A++
Sbjct: 65 PPGKLYQLIAPC--GLGERKSAYIYQLSQILVRDFHGEPPNDMALLTQLPGVGRKTASVF 122
Query: 133 LAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGK 192
L +G P PVDTH+ R+++R ++ SP E+ L E ++ ++ + +
Sbjct: 123 LGIAYGKPTFPVDTHILRLAQRWKISE-KKSPSAAEKDLARFFGHENTPKLHLQLIYYAR 181
Query: 193 SVCRPIKPRCDECPLKELCPRIGVQANSNQ 222
C + + D CP +C + +ANS +
Sbjct: 182 QYCPALHHKIDNCP---ICSYLAKEANSTR 208
>sp|Q09907|END3_SCHPO ENDONUCLEASE III HOMOLOG (DNA-(APURINIC OR APYRIMIDINIC SITE)
LYASE) >gi|2130197|pir||JC6066 endonuclease III (EC
3.1.-.-) - fission yeast (Schizosaccharomyces pombe)
>gi|2130406|pir||S62565 endonuclease III (EC 3.1.-.-)
homolog - fission yeast (Schizosaccharomyces pombe)
>gi|7490531|pir||T38592 endonuclease III homolog -
fission yeast (Schizosaccharomyces pombe)
>gi|1065894|emb|CAA91893.1| (Z67961) endonuclease III
homolog [Schizosaccharomyces pombe]
Length = 355
Score = 88.9 bits (217), Expect = 4e-17
Identities = 58/189 (30%), Positives = 96/189 (50%), Gaps = 19/189 (10%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNF----LRSL--KVGL 88
++TL+ ++S + +D V L ++ +E++QN L L KVG
Sbjct: 49 FQTLVALMLSSQTKDIVLGPTMRNLKEKLAG-----GLCLEDIQNIDEVSLNKLIEKVGF 103
Query: 89 WRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFG-IPAIPVDTH 147
K ++ + +RI+ EK++G +PD E+L+ LPG+G K + ++ + I VD H
Sbjct: 104 HNRKTIYLKQMARILSEKFQGDIPDTVEDLMTLPGVGPKMGYLCMSIAWNKTVGIGVDVH 163
Query: 148 VYRISRRLGLAPW--DASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDEC 205
V+RI L W + E+ L+ +P+E W +NH +V G+++C P RCD C
Sbjct: 164 VHRI---CNLLHWCNTKTEEQTRAALQSWLPKELWFELNHTLVGFGQTICLPRGRRCDMC 220
Query: 206 PL--KELCP 212
L K LCP
Sbjct: 221 TLSSKGLCP 229
>pir||E71969 a/g-specific adenine glycosylase - Helicobacter pylori (strain
J99) >gi|4154640|gb|AAD05709.1| (AE001452) A/G-SPECIFIC
ADENINE GLYCOSYLASE [Helicobacter pylori J99]
Length = 328
Score = 88.2 bits (215), Expect = 8e-17
Identities = 53/180 (29%), Positives = 100/180 (55%), Gaps = 7/180 (3%)
Query: 34 PYKTLIRCIISQRNR-DEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
PY+ I ++SQ+ + V +R K +P+++ +A+A +EE+ R L + S+
Sbjct: 31 PYEVYISEVMSQQTQISTVIERFYPPFLKAFPTLKDLANAPLEEVLLLWRGLG---YYSR 87
Query: 93 GKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRIS 152
K + +++ I ++++ ++P+ ++ L+KLPGIG AN +L +GF + VD +V R+
Sbjct: 88 AKNLKKSAEICVKEHHSQLPNDYQSLLKLPGIGAYTANAILCFGFREKSACVDANVKRVL 147
Query: 153 RRL-GLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
RL GL P + ++++ + + + E N A++D G +C P KP+C CP C
Sbjct: 148 LRLFGLDP-NIHAKDLQIKANDFLNLNESFNHNQALIDLGALICSP-KPKCAICPFNPYC 205
>pir||F64537 A/G-specific adenine glycosylase - Helicobacter pylori (strain
26695) >gi|2313226|gb|AAD07210.1| (AE000535)
A/G-specific adenine glycosylase (mutY) [Helicobacter
pylori 26695]
Length = 328
Score = 87.8 bits (214), Expect = 1e-16
Identities = 52/180 (28%), Positives = 100/180 (54%), Gaps = 7/180 (3%)
Query: 34 PYKTLIRCIISQRNR-DEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
PY+ I ++SQ+ + + V +R + +P+++ +A+A +EE+ R L + S+
Sbjct: 31 PYEVYISEVMSQQTQINTVIERFYSPFLEAFPTLKDLANAQLEEVLLLWRGLG---YYSR 87
Query: 93 GKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRIS 152
K + +++ I ++++ ++P+ ++ L+KLPGIG AN +L +GF VD ++ R+
Sbjct: 88 AKNLKKSAEICVKEHHSQLPNDYQSLLKLPGIGAYTANAILCFGFREKRACVDANIKRVL 147
Query: 153 RRL-GLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
RL GL P + ++++ + E + E N A++D G +C P KP+C CP C
Sbjct: 148 LRLFGLDP-NIHAKDLQIKANEFLNLNESFNHNQALIDLGALICSP-KPKCAICPFNPYC 205
>pir||B81745 endonuclease III TC0069 [imported] - Chlamydia muridarum (strain
Nigg) >gi|7190104|gb|AAF38952.1| (AE002274) endonuclease
III [Chlamydia muridarum]
Length = 210
Score = 87.4 bits (213), Expect = 1e-16
Identities = 54/195 (27%), Positives = 97/195 (49%), Gaps = 6/195 (3%)
Query: 16 IVQILKSTYPR-ERHVSG--DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASA 72
I+ L +P E + G P++ LI ++S + D+V + V LF + P ++++
Sbjct: 13 ILNTLNQLFPNPEPSLKGWHSPFQLLIAILLSGNSTDKVVNTVIPALFAKAPDAQSMSKL 72
Query: 73 SVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIV 132
+ E+ + + GL K +I E S I++E+Y P EL KLPG+GRK A++
Sbjct: 73 PLSEIYSLIAPC--GLGERKSVYIHELSCILVERYAQEPPRSLSELTKLPGVGRKTASVF 130
Query: 133 LAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGK 192
L+ +G PVDTH+ R++ R L+ SP E+ L + ++ ++ + +
Sbjct: 131 LSIYYGENTFPVDTHILRLAHRWKLST-KRSPSAAEKDLVAFFGKTNSPKLHLQLIYYAR 189
Query: 193 SVCRPIKPRCDECPL 207
C + + D CP+
Sbjct: 190 EYCPALHHKIDACPI 204
>pir||A72082 adenine glycosylase - Chlamydophila pneumoniae (strain CWL029)
>gi|4376682|gb|AAD18546.1| (AE001624) Adenine
Glycosylase [Chlamydophila pneumoniae CWL029]
>gi|8163415|gb|AAF73658.1| (AE002198) A/G-specific
adenine glycosylase [Chlamydophila pneumoniae AR39]
>gi|8978774|dbj|BAA98610.1| (AP002546) adenine
glycosylase [Chlamydophila pneumoniae J138]
Length = 369
Score = 83.5 bits (203), Expect = 2e-15
Identities = 46/182 (25%), Positives = 95/182 (51%), Gaps = 8/182 (4%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
PY + ++ Q+ R EV + +R+P+IE++A+A E++ L + S+
Sbjct: 37 PYSVWVSEVMLQQTRAEVVIDYFNQWMERFPTIESLAAAKEEDVIKLWEGLG---YYSRA 93
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
+ ++E +R+++E++ G++PD L ++ G+G + +LA+ F A VD +V R+
Sbjct: 94 RHLLEGARMVMEEFHGKIPDDAISLAQIRGVGPYTVHAILAFAFKRRAAAVDGNVLRVLS 153
Query: 154 RLGLAPWDASPEE----VEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKE 209
R+ L E V + L+P + + A+++ G +C+ + P+C CP+++
Sbjct: 154 RIFLIETSIDLESTRTWVSRIAQALLPHKSPEVIAEALIELGACICKKV-PQCHRCPVRQ 212
Query: 210 LC 211
C
Sbjct: 213 AC 214
>pir||C71482 probable endonuclease III - Chlamydia trachomatis (serotype D,
strain UW3/Cx) >gi|3329151|gb|AAC68292.1| (AE001340)
Endonuclease III [Chlamydia trachomatis]
Length = 211
Score = 83.1 bits (202), Expect = 3e-15
Identities = 52/205 (25%), Positives = 102/205 (49%), Gaps = 6/205 (2%)
Query: 6 SLSERERALKIVQILKSTYPRER-HVSG--DPYKTLIRCIISQRNRDEVTDRVSEELFKR 62
SL+ + + I+ L +P ++G P++ LI ++S + D+ + V+ LF +
Sbjct: 3 SLNVQAKRAFIISTLNRLFPNPAPSLTGWQTPFQLLIAILLSGNSTDKAVNSVTPSLFAK 62
Query: 63 YPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLP 122
P ++++ + E+ + + GL K +I S I++++Y P EL LP
Sbjct: 63 APDAQSMSMLAPSEIYSLIAPC--GLGERKAAYIHALSHILVDRYHQEPPHTLPELTALP 120
Query: 123 GIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIY 182
G+GRK A++ L+ +G PVDTH+ R++ R L+ SP VE+ L + +
Sbjct: 121 GVGRKTASVFLSIYYGENTFPVDTHILRLAHRWQLST-KRSPSAVEKDLVQFFGPKHSPK 179
Query: 183 VNHAMVDHGKSVCRPIKPRCDECPL 207
++ ++ + ++ C + D CP+
Sbjct: 180 LHLQLIYYARAYCPALHHNIDVCPI 204
>pir||D75275 endonuclease III - Deinococcus radiodurans (strain R1)
>gi|6460251|gb|AAF11977.1|AE002073_7 (AE002073)
endonuclease III [Deinococcus radiodurans]
Length = 259
Score = 82.7 bits (201), Expect = 3e-15
Identities = 60/189 (31%), Positives = 88/189 (45%), Gaps = 13/189 (6%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
DP LI I+SQR + +EL + +AI A + + + +R + SK
Sbjct: 48 DPMHELISTILSQRTTHADEEAAYQEL-RTLGDWDAITLAPTDAVAHAIR--RSNYPESK 104
Query: 93 GKWIVETSRIILEKYKGR---------VPDKFEELIKLPGIGRKCANIVLAYGFGIPAIP 143
I ET R I G V D + L LPG+G K A++VL + + P P
Sbjct: 105 APRIQETLRRIKAAPGGYDLDFLRDLPVKDALKWLTDLPGVGVKTASLVLLFNYARPVFP 164
Query: 144 VDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHA-MVDHGKSVCRPIKPRC 202
VDTHV+R+S R+G+ P L L P ++Y H + HG+ VC +P+C
Sbjct: 165 VDTHVHRVSTRVGVIPRMGEQAAHRALLALLPPDPPYLYELHINFLSHGRQVCTWTRPKC 224
Query: 203 DECPLKELC 211
+C L+E C
Sbjct: 225 GKCILRERC 233
>gi|10954471 ORF10 [Methanobacterium thermoautotrophicum]
>gi|232205|sp|P29588|GTMR_METTF POSSIBLE G-T MISMATCHES
REPAIR ENZYME (ORF10) >gi|282614|pir||S26447
hypothetical protein 10 - Methanobacterium
thermoformicicum plasmid pFV1 >gi|809723|emb|CAA48433.1|
(X68366) ORF10 [Methanobacterium thermoautotrophicum]
Length = 221
Score = 80.8 bits (196), Expect = 1e-14
Identities = 46/182 (25%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
DPY LI I+ +R ++ ++ F +Y E I E+ ++ ++GL +
Sbjct: 34 DPYVILITEILLRRTTAGHVKKIYDKFFVKYKCFEDILKTPKSEIAKDIK--EIGLSNQR 91
Query: 93 GKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRIS 152
+ + E +R+++ Y GRVP + ++ LPG+G+ V+ FG A VD + R+
Sbjct: 92 AEQLKELARVVINDYGGRVPRNRKAILDLPGVGKYTCAAVMCLAFGKKAAMVDANFVRVI 151
Query: 153 RRLGLAPWD---ASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKE 209
R ++ + + + E + L+P + N ++D +C P KP+C++C + +
Sbjct: 152 NRYFGGSYENLNYNHKALWELAETLVPGGKCRDFNLGLMDFSAIICAPRKPKCEKCGMSK 211
Query: 210 LC 211
LC
Sbjct: 212 LC 213
>pir||S30312 endonuclease III homolog - Methanobacterium thermoformicicum
plasmid pFV1
Length = 221
Score = 80.8 bits (196), Expect = 1e-14
Identities = 46/182 (25%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
DPY LI I+ +R ++ ++ F +Y E I E+ ++ ++GL +
Sbjct: 34 DPYVILITEILLRRTTAGHVKKIYDKFFVKYKCFEDILKTPKSEIAKDIK--EIGLSNQR 91
Query: 93 GKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRIS 152
+ + E +R+++ Y GRVP + ++ LPG+G+ V+ FG A VD + R+
Sbjct: 92 AEQLKELARVVINDYGGRVPRNRKAILDLPGVGKYTCAAVMCLAFGKKAAMVDANFVRVI 151
Query: 153 RRLGLAPWD---ASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKE 209
R ++ + + + E + L+P + N ++D +C P KP+C++C + +
Sbjct: 152 NRYFGGSYENLNYNHKALWELAETLVPGGKCRDFNLGLMDFSAIICAPRKPKCEKCGMSK 211
Query: 210 LC 211
LC
Sbjct: 212 LC 213
>sp|P57617|MUTY_BUCAI A/G-SPECIFIC ADENINE GLYCOSYLASE >gi|10039210|dbj|BAB13244.1|
(AP001119) A/G-specific adenine glycosylase [Buchnera
sp. APS]
Length = 350
Score = 79.6 bits (193), Expect = 3e-14
Identities = 55/184 (29%), Positives = 95/184 (50%), Gaps = 11/184 (5%)
Query: 36 KTLIRCIISQRNRDEVTDRVSEELFKRY----PSIEAIASASVEEMQNFLRSLKVGLWRS 91
KTL IS+ + T + + FK++ P+I+++ + ++++ L + +
Sbjct: 28 KTLYTVWISEIMLQQTTVKSAIPYFKKFILNFPNIKSLNDSKLDDVLYLWSGLG---YYN 84
Query: 92 KGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRI 151
+ K I ++++II +KYKG PD+F +I+LPGIGR A +L+ +D +V RI
Sbjct: 85 RAKNIYKSAQIIKKKYKGIFPDQFSNIIQLPGIGRSTAGAILSLSLNFFYPILDGNVKRI 144
Query: 152 SRRLGLAPWDASPEEVEERLKELI----PREEWIYVNHAMVDHGKSVCRPIKPRCDECPL 207
R +++E++L +I P N M+D G S+C IKP+C CPL
Sbjct: 145 LVRYYGISGLLKDKKIEKKLWNIIESITPIHNTGKFNQGMMDIGASICISIKPKCTICPL 204
Query: 208 KELC 211
K+ C
Sbjct: 205 KKEC 208
>gb|AAC46007.1| (AF009362) putative endonuclease III [Clostridium butyricum]
Length = 113
Score = 78.8 bits (191), Expect = 5e-14
Identities = 39/111 (35%), Positives = 66/111 (59%), Gaps = 2/111 (1%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
+ L++ + D+ + V +ELFK YP ++A + +E++ ++ ++GL+R+K K
Sbjct: 5 FNFLLQLCYLHKTTDKKVNEVPKELFKDYPDLDAFLEITNDELEERIK--QIGLYRNKSK 62
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVD 145
++ R I EK+ G VP E + L G GRK AN+VL+ FG+P+I VD
Sbjct: 63 NLILMFRQIKEKFNGEVPTTMEGITSLAGAGRKTANVVLSNAFGVPSIAVD 113
>dbj|BAB04650.1| (AP001510) adenine glycosylase [Bacillus halodurans]
Length = 372
Score = 76.9 bits (186), Expect = 2e-13
Identities = 47/183 (25%), Positives = 88/183 (47%), Gaps = 7/183 (3%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
DPY+ + I+ Q+ R + + +++P++E +A A +++ L + S+
Sbjct: 35 DPYRVWVSEIMLQQTRVDTVIPYYQAFMRQFPTLETLAYAEEDQVLKAWEGLG---YYSR 91
Query: 93 GKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRIS 152
+ + R ++E Y G VP +E+ KL G+G A +L+ + P VD +V R+
Sbjct: 92 ARNLQSAVREVVESYGGEVPSTRKEISKLKGVGPYTAGAILSIAYDQPEPAVDGNVMRVL 151
Query: 153 RRLGLAPWDASPEEV----EERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLK 208
R+ D + + E L +LI +E + N +++ G VC P P C CP++
Sbjct: 152 SRVLYIEEDIAKVKTRTLFESLLYDLISKENPSFFNQGLMELGALVCTPTSPGCLLCPVR 211
Query: 209 ELC 211
+ C
Sbjct: 212 DHC 214
>gb|AAF37270.1|AF222335_1 (AF222335) U/G and T/G mismatch-specific DNA glycosylase
[Pyrobaculum aerophilum]
Length = 230
Score = 75.7 bits (183), Expect = 4e-13
Identities = 48/183 (26%), Positives = 91/183 (49%), Gaps = 8/183 (4%)
Query: 31 SGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWR 90
+GDP+ L+ ++ ++ + + E +RYPS +A ASVEE++ ++ L G+
Sbjct: 36 AGDPWAVLVAALLLRKTTVKQVVDIYREFLRRYPSPARLADASVEEIKAIIQPL--GMEH 93
Query: 91 SKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYR 150
+ + + S ++ ++ G++P + L LPG+G A+ VL G P +D ++ R
Sbjct: 94 VRATLLKKLSEELVRRFNGQIPCDRDALKSLPGVGDYAASEVLLTACGKPEPLLDRNMIR 153
Query: 151 ISRRL-GLAPWDASP---EEVEERLKELIPREEWI--YVNHAMVDHGKSVCRPIKPRCDE 204
+ R+ G+ P E+ + L+PR+ + N ++D + VC P+C
Sbjct: 154 VIERVFGIKSKKRRPHTDRELWNFARSLVPRDPELAKEFNFGVLDFARKVCTAKSPKCSL 213
Query: 205 CPL 207
CPL
Sbjct: 214 CPL 216
>pir||A81709 A/G-specific adenine glycosylase TC0383 [imported] - Chlamydia
muridarum (strain Nigg) >gi|7190423|gb|AAF39240.1|
(AE002305) A/G-specific adenine glycosylase [Chlamydia
muridarum]
Length = 371
Score = 75.7 bits (183), Expect = 4e-13
Identities = 51/185 (27%), Positives = 88/185 (47%), Gaps = 8/185 (4%)
Query: 31 SGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWR 90
S PY+ + ++ Q+ R EV +R+PSI+ +A A E+ L +
Sbjct: 34 SPTPYRVWVSEVMLQQTRAEVVVPYFLRWMERFPSIQDLAHAEESEVVRLWEGLG---YY 90
Query: 91 SKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYR 150
S+ + ++ +R+I E ++G +P L + GIG AN +LA+ F VD +V R
Sbjct: 91 SRARNLLSGARVITELFQGEIPQDPLLLNSIKGIGPYTANAILAFAFKQKKAAVDGNVLR 150
Query: 151 ISRRLGLAPWD----ASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECP 206
+ RL + +E+ E + L+P E + A ++ G +C KP C++CP
Sbjct: 151 VMSRLFAINQSIDRIKTRQEITELCETLLPDYEPEVIAEAFIELGARICNR-KPVCEQCP 209
Query: 207 LKELC 211
L+ C
Sbjct: 210 LRSFC 214
>pir||B69165 endonuclease III homolog - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621567|gb|AAB85002.1| (AE000833)
endonuclease III homolog [Methanobacterium
thermoautotrophicum]
Length = 175
Score = 74.9 bits (181), Expect = 7e-13
Identities = 48/169 (28%), Positives = 90/169 (52%), Gaps = 6/169 (3%)
Query: 46 RNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILE 105
R R E + E +++P +++ A E ++ + SL + WR++ + + + I
Sbjct: 4 RTRAEQVLEIYENFVEKFPDFKSVCEAGQETIEKEMESLGLR-WRARN--LHKLACEIES 60
Query: 106 KYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDAS- 163
++ G VP +L++LPGIG ++ L + IP +DT+ RI RL L D+S
Sbjct: 61 RHGGAVPKNKNDLLELPGIGNYISSAFLCFSKNIPEPLLDTNTVRIIGRLFDLEISDSSR 120
Query: 164 -PEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
++ E +++++ + +++ +M+D G++VCR P C ECPLK C
Sbjct: 121 RKKDFETVMRKILEFGDCRHLSLSMIDFGEAVCRASDPLCHECPLKLSC 169
>pir||C72770 probable DNA-(apurinic or apyrimidinic site)lyase APE0150 -
Aeropyrum pernix (strain K1) >gi|5103540|dbj|BAA79061.1|
(AP000058) 264aa long hypothetical DNA-(apurinic or
apyrimidinic site)lyase [Aeropyrum pernix]
Length = 264
Score = 74.5 bits (180), Expect = 1e-12
Identities = 53/189 (28%), Positives = 94/189 (49%), Gaps = 10/189 (5%)
Query: 32 GDPYKTLIRCIISQRNRDEVTDRVSEELFKRYP-SIEAIASASVEEMQNFLRSLKVGLWR 90
G+P+ L ++SQ D+ + R +L + + EAI AS +++ +R + GL R
Sbjct: 75 GNPFAVLAAVVLSQNTNDKNSIRAYLKLRQTIGVTPEAILEASYDDLVEAIR--EAGLPR 132
Query: 91 SKGKWIVETSRIIL----EKYKGRVPDKF--EELIKLPGIGRKCANIVLAYGFGIPAI-P 143
K + + ++ E Y + P + E+L+ + GIG K A++ L+ P +
Sbjct: 133 QKASALKALAEAVVRWGGENYLLKAPPEELREKLMSIRGIGPKTADVFLSLVRKAPGVFA 192
Query: 144 VDTHVYRISRRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCD 203
VDTH R++RR GL A +E+ + L + ++ G++ C+ +PRC
Sbjct: 193 VDTHAARVARRWGLVGEKAGYDEISKALYNYFGPGNSEEAHRLIIALGRTYCKARRPRCR 252
Query: 204 ECPLKELCP 212
ECPL+ +CP
Sbjct: 253 ECPLRSVCP 261
>pir||G83003 A / G specific adenine glycosylase PA5147 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951447|gb|AAG08532.1|AE004927_10 (AE004927) A / G
specific adenine glycosylase [Pseudomonas aeruginosa]
Length = 355
Score = 74.1 bits (179), Expect = 1e-12
Identities = 48/182 (26%), Positives = 88/182 (47%), Gaps = 7/182 (3%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
PY+ + I+ Q+ + + P +EA+A+A+ +E+ + L + S+
Sbjct: 30 PYRVWVSEIMLQQTQVSTVLGYFDRFMAALPDVEALAAAAEDEVLHLWTGLG---YYSRA 86
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRI-S 152
+ + +T++I++E++ G P E+L +LPGIGR A + + G+ A +D +V R+ +
Sbjct: 87 RNLHKTAQIVVERHAGEFPRDVEQLAELPGIGRSTAGAIASLSMGLRAPILDGNVKRVLA 146
Query: 153 RRLGLAPWDASPEEVE---ERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKE 209
R L + P+ E + P + AM+D G ++C KP C CPL
Sbjct: 147 RYLAQDGYPGEPKVARALWEAAERFTPHARVNHYTQAMMDLGATLCTRSKPSCLLCPLVS 206
Query: 210 LC 211
C
Sbjct: 207 GC 208
>sp|P17802|MUTY_ECOLI A/G-SPECIFIC ADENINE GLYCOSYLASE >gi|96182|pir||B38535 A/G-specific
adenine glycosylase (EC 3.2.2.-) [validated] -
Escherichia coli >gi|42073|emb|CAA36624.1| (X52391)
adenine glycosylase (AA 1-350) [Escherichia coli]
>gi|146864|gb|AAA72957.1| (M59471) A/G-specific adenine
glycosylase [Escherichia coli] >gi|882490|gb|AAA69128.1|
(U28377) CG Site No. 18130; alternate name micA
[Escherichia coli] >gi|1789331|gb|AAC75998.1| (AE000378)
adenine glycosylase; G.C --> T.A transversions
[Escherichia coli K12]
Length = 350
Score = 73.7 bits (178), Expect = 2e-12
Identities = 46/182 (25%), Positives = 88/182 (48%), Gaps = 7/182 (3%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
PYK + ++ Q+ + E R+P++ +A+A ++E+ + L + ++
Sbjct: 30 PYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLG---YYARA 86
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
+ + + ++ + + G+ P+ FEE+ LPG+GR A +L+ G +D +V R+
Sbjct: 87 RNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLA 146
Query: 154 RLGLAPWDASPEEVEERL----KELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKE 209
R +EVE +L +++ P N AM+D G +C KP+C CPL+
Sbjct: 147 RCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQN 206
Query: 210 LC 211
C
Sbjct: 207 GC 208
>pdb|1MUY|A Chain A, Catalytic Domain Of Muty From Escherichia Coli
Length = 225
Score = 73.7 bits (178), Expect = 2e-12
Identities = 46/182 (25%), Positives = 88/182 (48%), Gaps = 7/182 (3%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
PYK + ++ Q+ + E R+P++ +A+A ++E+ + L + ++
Sbjct: 30 PYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLG---YYARA 86
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
+ + + ++ + + G+ P+ FEE+ LPG+GR A +L+ G +D +V R+
Sbjct: 87 RNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLA 146
Query: 154 RLGLAPWDASPEEVEERL----KELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKE 209
R +EVE +L +++ P N AM+D G +C KP+C CPL+
Sbjct: 147 RCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQN 206
Query: 210 LC 211
C
Sbjct: 207 GC 208
>gi|6912520 mutY (E. coli) homolog [Homo sapiens] >gi|6691521|dbj|BAA89336.1|
(AB032920) hMYHalpha1 [Homo sapiens]
Length = 546
Score = 73.4 bits (177), Expect = 2e-12
Identities = 47/156 (30%), Positives = 84/156 (53%), Gaps = 8/156 (5%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
+++P+++ +ASAS+EE+ L + S+G+ + E +R ++E+ G +P E L +
Sbjct: 151 QKWPTLQDLASASLEEVNQLWAGLG---YYSRGRRLQEGARKVVEELGGHMPRTAETLQQ 207
Query: 121 L-PGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERL----KELI 175
L PG+GR A + + FG VD +V R+ R+ D S V ++L ++L+
Sbjct: 208 LLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLV 267
Query: 176 PREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
N A ++ G +VC P +P C +CP++ LC
Sbjct: 268 DPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLC 303
>dbj|BAA89337.1| (AB032921) hMYHalpha2 [Homo sapiens]
Length = 536
Score = 73.4 bits (177), Expect = 2e-12
Identities = 47/156 (30%), Positives = 84/156 (53%), Gaps = 8/156 (5%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
+++P+++ +ASAS+EE+ L + S+G+ + E +R ++E+ G +P E L +
Sbjct: 141 QKWPTLQDLASASLEEVNQLWAGLG---YYSRGRRLQEGARKVVEELGGHMPRTAETLQQ 197
Query: 121 L-PGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERL----KELI 175
L PG+GR A + + FG VD +V R+ R+ D S V ++L ++L+
Sbjct: 198 LLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLV 257
Query: 176 PREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
N A ++ G +VC P +P C +CP++ LC
Sbjct: 258 DPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLC 293
>dbj|BAA89339.1| (AB032923) hMYHalpha4 [Homo sapiens] >gi|6691539|dbj|BAA89345.1|
(AB032929) hMYHgamma4 [Homo sapiens]
Length = 429
Score = 73.4 bits (177), Expect = 2e-12
Identities = 47/156 (30%), Positives = 84/156 (53%), Gaps = 8/156 (5%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
+++P+++ +ASAS+EE+ L + S+G+ + E +R ++E+ G +P E L +
Sbjct: 34 QKWPTLQDLASASLEEVNQLWAGLG---YYSRGRRLQEGARKVVEELGGHMPRTAETLQQ 90
Query: 121 L-PGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERL----KELI 175
L PG+GR A + + FG VD +V R+ R+ D S V ++L ++L+
Sbjct: 91 LLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLV 150
Query: 176 PREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
N A ++ G +VC P +P C +CP++ LC
Sbjct: 151 DPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLC 186
>dbj|BAA89340.1| (AB032924) hMYHbeta1 [Homo sapiens]
Length = 532
Score = 73.4 bits (177), Expect = 2e-12
Identities = 47/156 (30%), Positives = 84/156 (53%), Gaps = 8/156 (5%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
+++P+++ +ASAS+EE+ L + S+G+ + E +R ++E+ G +P E L +
Sbjct: 137 QKWPTLQDLASASLEEVNQLWAGLG---YYSRGRRLQEGARKVVEELGGHMPRTAETLQQ 193
Query: 121 L-PGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERL----KELI 175
L PG+GR A + + FG VD +V R+ R+ D S V ++L ++L+
Sbjct: 194 LLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLV 253
Query: 176 PREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
N A ++ G +VC P +P C +CP++ LC
Sbjct: 254 DPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLC 289
>dbj|BAA89341.1| (AB032925) hMYHbeta3 [Homo sapiens] >gi|6691533|dbj|BAA89342.1|
(AB032926) hMYHbeta5 [Homo sapiens]
>gi|6691537|dbj|BAA89344.1| (AB032928) hMYHgamma3 [Homo
sapiens]
Length = 521
Score = 73.4 bits (177), Expect = 2e-12
Identities = 47/156 (30%), Positives = 84/156 (53%), Gaps = 8/156 (5%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
+++P+++ +ASAS+EE+ L + S+G+ + E +R ++E+ G +P E L +
Sbjct: 126 QKWPTLQDLASASLEEVNQLWAGLG---YYSRGRRLQEGARKVVEELGGHMPRTAETLQQ 182
Query: 121 L-PGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERL----KELI 175
L PG+GR A + + FG VD +V R+ R+ D S V ++L ++L+
Sbjct: 183 LLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLV 242
Query: 176 PREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
N A ++ G +VC P +P C +CP++ LC
Sbjct: 243 DPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLC 278
>gb|AAC50618.1| (U63329) mutY homolog [Homo sapiens] >gi|6691525|dbj|BAA89338.1|
(AB032922) hMYHalpha3 [Homo sapiens]
Length = 535
Score = 73.4 bits (177), Expect = 2e-12
Identities = 47/156 (30%), Positives = 84/156 (53%), Gaps = 8/156 (5%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
+++P+++ +ASAS+EE+ L + S+G+ + E +R ++E+ G +P E L +
Sbjct: 140 QKWPTLQDLASASLEEVNQLWAGLG---YYSRGRRLQEGARKVVEELGGHMPRTAETLQQ 196
Query: 121 L-PGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERL----KELI 175
L PG+GR A + + FG VD +V R+ R+ D S V ++L ++L+
Sbjct: 197 LLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLV 256
Query: 176 PREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
N A ++ G +VC P +P C +CP++ LC
Sbjct: 257 DPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLC 292
>dbj|BAA89343.1| (AB032927) hMYHgamma2 [Homo sapiens]
Length = 522
Score = 73.4 bits (177), Expect = 2e-12
Identities = 47/156 (30%), Positives = 84/156 (53%), Gaps = 8/156 (5%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
+++P+++ +ASAS+EE+ L + S+G+ + E +R ++E+ G +P E L +
Sbjct: 127 QKWPTLQDLASASLEEVNQLWAGLG---YYSRGRRLQEGARKVVEELGGHMPRTAETLQQ 183
Query: 121 L-PGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERL----KELI 175
L PG+GR A + + FG VD +V R+ R+ D S V ++L ++L+
Sbjct: 184 LLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLV 243
Query: 176 PREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
N A ++ G +VC P +P C +CP++ LC
Sbjct: 244 DPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLC 279
>sp|P44320|MUTY_HAEIN A/G-SPECIFIC ADENINE GLYCOSYLASE >gi|1073805|pir||C64091 adenine
glycosylase - Haemophilus influenzae (strain Rd KW20)
>gi|1573768|gb|AAC22418.1| (U32760) A/G-specific adenine
glycosylase (mutY) [Haemophilus influenzae Rd]
Length = 378
Score = 72.6 bits (175), Expect = 4e-12
Identities = 45/159 (28%), Positives = 80/159 (50%), Gaps = 7/159 (4%)
Query: 57 EELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFE 116
E K +P+I A+A+AS +E+ + L + ++ + + + ++ + +++ G P FE
Sbjct: 58 ERFIKTFPNITALANASQDEVLHLWTGLG---YYARARNLHKAAQKVRDEFNGNFPTNFE 114
Query: 117 ELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERL----K 172
++ L G+GR A +L+ P +D +V R+ R + ++VE RL +
Sbjct: 115 QVWALSGVGRSTAGAILSSVLNQPYPILDGNVKRVLARYFAVEGWSGEKKVENRLWALTE 174
Query: 173 ELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
++ P N AM+D G VC KP+CD CPL C
Sbjct: 175 QVTPTTRVADFNQAMMDIGAMVCMRTKPKCDLCPLNIDC 213
>pir||D82320 A/G-specific adenine glycosylase VC0452 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9654877|gb|AAF93625.1| (AE004132) A/G-specific
adenine glycosylase [Vibrio cholerae]
Length = 353
Score = 72.6 bits (175), Expect = 4e-12
Identities = 46/182 (25%), Positives = 92/182 (50%), Gaps = 9/182 (4%)
Query: 35 YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGK 94
Y+ + I+ Q+ + E +R+P++ A+A+A +E+ +F L + ++ +
Sbjct: 29 YRVWLSEIMLQQTQVATVIPYFERFLERFPTVHALAAAPQDEVLHFWTGLG---YYARAR 85
Query: 95 WIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYR-ISR 153
+ + +++++ +Y G P E++ LPG+GR A VL+ + P +D +V R ++R
Sbjct: 86 NLHKAAQMVVSEYGGEFPTDLEQMNALPGVGRSTAAAVLSSVYKKPHAILDGNVKRTLAR 145
Query: 154 RLGLAPWDASPEEVEERL----KELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKE 209
+ W + VE +L + P+ + N AM+D G +C KP+C CP++
Sbjct: 146 CFAVEGWPGQ-KSVENQLWHYAEMHTPKVDVDKYNQAMMDMGAMICTRSKPKCSLCPVES 204
Query: 210 LC 211
C
Sbjct: 205 FC 206
>pdb|1MUN| Catalytic Domain Of Muty From Escherichia Coli D138n Mutant
>gi|6137464|pdb|1MUD|A Chain A, Catalytic Domain Of Muty
From Escherichia Coli, D138n Mutant Complexed To Adenine
Length = 225
Score = 71.8 bits (173), Expect = 6e-12
Identities = 45/182 (24%), Positives = 88/182 (47%), Gaps = 7/182 (3%)
Query: 34 PYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKG 93
PYK + ++ Q+ + E R+P++ +A+A ++E+ + L + ++
Sbjct: 30 PYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLG---YYARA 86
Query: 94 KWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISR 153
+ + + ++ + + G+ P+ FEE+ LPG+GR A +L+ G ++ +V R+
Sbjct: 87 RNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILNGNVKRVLA 146
Query: 154 RLGLAPWDASPEEVEERL----KELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKE 209
R +EVE +L +++ P N AM+D G +C KP+C CPL+
Sbjct: 147 RCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQN 206
Query: 210 LC 211
C
Sbjct: 207 GC 208
>gb|AAG19811.1| (AE005065) A/G specific adenine glycosylase, repair protein; MutY
[Halobacterium sp. NRC-1]
Length = 312
Score = 71.4 bits (172), Expect = 8e-12
Identities = 50/181 (27%), Positives = 86/181 (46%), Gaps = 4/181 (2%)
Query: 33 DPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSK 92
DPY+ L+ ++SQ+ + R+P+ A+A+A ++ F + +G + ++
Sbjct: 43 DPYEILVSEVMSQQTQLSRVIDAWRAFLDRWPTTAALAAADRSDVVGFWSAHSLG-YNNR 101
Query: 93 GKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRIS 152
+ E ++ + Y G +P EL +L G+G AN V ++ F VDT+V R+
Sbjct: 102 ATHLHEAAQQVETDYDGAIPRTPAELSELMGVGPYTANAVASFAFNAGNAVVDTNVKRVL 161
Query: 153 RRLGLAPWDASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCD--ECPLKEL 210
R D + EL+P N+A+++ G C+ PRCD ECPL+E
Sbjct: 162 YRAFEGIRDDDDPDYRPLANELLPDGTSRVWNNAVMELGAVACQQ-TPRCDEAECPLREW 220
Query: 211 C 211
C
Sbjct: 221 C 221
>pir||A64479 DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) -
Methanococcus jannaschii >gi|1592082|gb|AAB99444.1|
(U67584) endonuclease III, putative (nth2)
[Methanococcus jannaschii]
Length = 220
Score = 70.6 bits (170), Expect = 1e-11
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 20/216 (9%)
Query: 11 ERALKIVQILKSTYPRERHVSGDP-YKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAI 69
E KI +IL Y + + Y+ ++ I++Q + +R L K +E +
Sbjct: 7 EMIYKIYKILLDYYGHQNWWPAETRYEVVVGAILTQNTSWKNVERAINNL-KMEDLLEEV 65
Query: 70 ASASVEE--MQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFE----------E 117
+V+E ++ +R G + K K + ++ I+E Y G + + E
Sbjct: 66 KILNVDEDKLKELIRP--AGFYNLKAKRLKNVTKFIVENY-GNTEEMAKTDKDTLILRAE 122
Query: 118 LIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWDASPEEVEERLKELIPR 177
L+ + G+G++ A+ +L Y + VD + R+ RLG+ A +E++E ++ +P+
Sbjct: 123 LLSINGVGKETADSILLYALDRESFVVDAYTKRMFSRLGVINEKAKYDEIKEIFEKNLPK 182
Query: 178 EEWIYVN-HAM-VDHGKSVCRPIKPRCDECPLKELC 211
+ IY HA+ V+H K CR K CD CP+KE C
Sbjct: 183 DLEIYKEYHALIVEHCKKFCRK-KALCDNCPIKEFC 217
>sp|Q05869|MUTY_SALTY A/G-SPECIFIC ADENINE GLYCOSYLASE >gi|538800|pir||A40647
methylation-independent repair protein mutB - Salmonella
typhimurium >gi|154184|gb|AAA27165.1| (M86634) mutB
[Salmonella typhimurium]
Length = 350
Score = 70.2 bits (169), Expect = 2e-11
Identities = 46/186 (24%), Positives = 86/186 (45%), Gaps = 7/186 (3%)
Query: 30 VSGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLW 89
++ PYK + ++ Q+ + E R+P++ +A+A ++E+ + L +
Sbjct: 26 INKTPYKVWLSEVMLQQTQVTTVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLG---Y 82
Query: 90 RSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVY 149
++ + + + ++ + + G P F E+ LPG+GR A +L+ G +D +V
Sbjct: 83 YARARNLHKAAQQVATLHGGEFPQTFAEIAALPGVGRSTAGAILSLALGKHYPILDGNVK 142
Query: 150 RISRRLGLAPWDASPEEVEERL----KELIPREEWIYVNHAMVDHGKSVCRPIKPRCDEC 205
R+ R +EVE L +++ P N AM+D G VC KP+C C
Sbjct: 143 RVLARCYAVSGWPGKKEVENTLWTLSEQVTPARGVERFNQAMMDLGAMVCTRSKPKCTLC 202
Query: 206 PLKELC 211
PL+ C
Sbjct: 203 PLQNGC 208
>emb|CAB37760.1| (AJ239649) MutY protein [Helicobacter pylori]
Length = 140
Score = 70.2 bits (169), Expect = 2e-11
Identities = 40/138 (28%), Positives = 80/138 (56%), Gaps = 5/138 (3%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
K +P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P+ ++ L+K
Sbjct: 7 KAFPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHHSQLPNDYQSLLK 63
Query: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREE 179
LPGIG AN +L +GF + VD ++ R+ RL GL P + ++++ + E + E
Sbjct: 64 LPGIGAYTANAILCFGFREKSACVDANIKRVLLRLFGLDP-NIHAKDLQIKANEFLNLNE 122
Query: 180 WIYVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 123 SFNHNQALIDLGALICSP 140
>emb|CAB37762.1| (AJ239651) MutY protein [Helicobacter pylori]
Length = 140
Score = 70.2 bits (169), Expect = 2e-11
Identities = 39/138 (28%), Positives = 81/138 (58%), Gaps = 5/138 (3%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
K +P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P+ ++ L+K
Sbjct: 7 KAFPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHNSQLPNDYQSLLK 63
Query: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREE 179
LPGIG AN +L +GF + VD ++ R+ RL GL P + + ++++ + + + E
Sbjct: 64 LPGIGAYTANAILCFGFREKSACVDANIKRVLLRLFGLDP-NITAKDLQIKANDFLNLNE 122
Query: 180 WIYVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 123 SFNHNQALIDLGALICSP 140
>pir||A69802 A/G-specific adenine glycosylase homolog yfhQ - Bacillus subtilis
>gi|2633186|emb|CAB12691.1| (Z99108) similar to
A/G-specific adenine glycosylase [Bacillus subtilis]
>gi|2804547|dbj|BAA24483.1| (D85082) YfhQ [Bacillus
subtilis]
Length = 369
Score = 69.9 bits (168), Expect = 2e-11
Identities = 52/202 (25%), Positives = 96/202 (46%), Gaps = 14/202 (6%)
Query: 20 LKSTYPRERHV-----SGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASV 74
L S + RE+ V DPYK + ++ Q+ R E +++P++EA+A A
Sbjct: 20 LISWFEREQRVLPWREDQDPYKVWVSEVMLQQTRVETVIPYFLRFVEQFPTVEALADADE 79
Query: 75 EEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLA 134
E++ L + S+ + + + + ++Y G VP ++ L G+G VL+
Sbjct: 80 EKVLKAWEGLG---YYSRVRNLQSAVKEVKQEYGGIVPPDEKDFGGLKGVGPYTKGAVLS 136
Query: 135 YGFGIPAIPVDTHVYRISRRLGLAPWD--ASPEE---VEERLKELIPREEWIYVNHAMVD 189
+ P VD +V R+ R+ L+ WD A P+ E+ ++ I +E+ N +++
Sbjct: 137 IAYNKPIPAVDGNVMRVMSRI-LSIWDDIAKPKTRTIFEDAIRAFISKEKPSEFNQGLME 195
Query: 190 HGKSVCRPIKPRCDECPLKELC 211
G +C P P C CP+++ C
Sbjct: 196 LGALICTPKSPSCLLCPVQQHC 217
>emb|CAB37759.1| (AJ239648) MutY protein [Helicobacter pylori]
Length = 140
Score = 69.9 bits (168), Expect = 2e-11
Identities = 39/138 (28%), Positives = 81/138 (58%), Gaps = 5/138 (3%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
K +P+++ +A+A +E++ R L + S+ K + +++ I +++Y ++P+ ++ L+K
Sbjct: 7 KAFPTLKDLANAPLEKVLLLWRGLG---YYSRAKNLKKSAEICVKEYDSQLPNDYQSLLK 63
Query: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREE 179
LPGIG AN +L +GF + VD ++ R+ RL GL P + + ++++ + + + E
Sbjct: 64 LPGIGAYTANAILCFGFREKSACVDANIKRVLLRLFGLNP-NITAKDLQIKANDFLNLNE 122
Query: 180 WIYVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 123 SFNHNQALIDLGALICSP 140
>pir||B71557 probable adenine glycosylase - Chlamydia trachomatis (serotype D,
strain UW3/Cx) >gi|3328504|gb|AAC67698.1| (AE001284)
A/G-specific Adenine Glycosylase [Chlamydia trachomatis]
Length = 369
Score = 69.5 bits (167), Expect = 3e-11
Identities = 44/185 (23%), Positives = 89/185 (47%), Gaps = 8/185 (4%)
Query: 31 SGDPYKTLIRCIISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWR 90
S PY+ + ++ Q+ R EV + +R+P+++ +A A ++ L +
Sbjct: 34 SPTPYRVWVSEVMLQQTRAEVVVPYFLKWMERFPTLQDLAQARESDVVQLWEGLG---YY 90
Query: 91 SKGKWIVETSRIILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYR 150
S+ + ++ +R+I E + G +P+ L + GIG AN +LA+ F VD +V R
Sbjct: 91 SRARNLLAGARVITEIFGGEIPNDLALLSSIKGIGSYTANAILAFAFKQKNPAVDGNVLR 150
Query: 151 ISRRLGLAPWDA----SPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECP 206
+ RL + E+ + L+P ++ + + ++ G +C+ +P C++CP
Sbjct: 151 VMSRLFAIEESIDRMNTRREITGLCESLLPDQDPQVIAESFIELGARICKK-QPLCEQCP 209
Query: 207 LKELC 211
L+ C
Sbjct: 210 LRSFC 214
>pir||B81258 A/G-specific adenine glycosylase (EC 3.2.2.-) Cj1620c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6969037|emb|CAB73608.1| (AL139079) A/G-specific
adenine glycosylase [Campylobacter jejuni]
Length = 339
Score = 69.5 bits (167), Expect = 3e-11
Identities = 44/170 (25%), Positives = 87/170 (50%), Gaps = 4/170 (2%)
Query: 42 IISQRNRDEVTDRVSEELFKRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSR 101
++ Q V +R +++P++E++A+A+ +E+ + L + ++ + + + +
Sbjct: 54 MLQQTQVKSVLERFYFPFLQKFPTLESLANANEDELLKAWQGLG---YYTRARNLKKAAL 110
Query: 102 IILEKYKGRVPDKFEELIKLPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRLGLAPWD 161
++K+ ++P E+L KL GIG A + +G+ VD ++ R+ RL A +
Sbjct: 111 ECVDKFGAKLPKDVEDLKKLSGIGAYTAGAIACFGYDQKVSFVDGNIRRVLSRL-FALEN 169
Query: 162 ASPEEVEERLKELIPREEWIYVNHAMVDHGKSVCRPIKPRCDECPLKELC 211
S +E+E+R KEL+ N A++D G VC +C CPL + C
Sbjct: 170 PSMKELEKRAKELLNLNHAFDHNQALLDIGALVCVGKNAKCRICPLYDFC 219
>emb|CAB37763.1| (AJ239652) MutY protein [Helicobacter pylori]
Length = 140
Score = 69.1 bits (166), Expect = 4e-11
Identities = 39/138 (28%), Positives = 80/138 (57%), Gaps = 5/138 (3%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
K +P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P+ ++ L+K
Sbjct: 7 KAFPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHDSQLPNDYQSLLK 63
Query: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREE 179
LPGIG AN +L +GF VD ++ R+ RL GL P + + ++++ + + + E
Sbjct: 64 LPGIGTYTANAILCFGFREKRACVDANIKRVLLRLFGLDP-NITAKDLQIKANDFLNLNE 122
Query: 180 WIYVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 123 SFNHNQALIDLGALICSP 140
>emb|CAB37767.1| (AJ239656) MutY protein [Helicobacter pylori]
Length = 140
Score = 69.1 bits (166), Expect = 4e-11
Identities = 39/136 (28%), Positives = 78/136 (56%), Gaps = 5/136 (3%)
Query: 63 YPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLP 122
+P+++ +A+A +EE+ R L + S+ K + +++ I ++Y ++P+ ++ L+KLP
Sbjct: 9 FPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICAKEYNSQLPNDYQSLLKLP 65
Query: 123 GIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREEWI 181
GIG AN +L +GF + VD ++ R+ RL GL P + ++++ + + + E
Sbjct: 66 GIGAYTANAILCFGFREKSACVDANIKRVLLRLFGLDP-NIHAKDLQIKANDFLNPNESF 124
Query: 182 YVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 125 NHNQALIDLGALICSP 140
>emb|CAB37761.1| (AJ239650) MutY protein [Helicobacter pylori]
Length = 140
Score = 68.7 bits (165), Expect = 6e-11
Identities = 38/136 (27%), Positives = 80/136 (57%), Gaps = 5/136 (3%)
Query: 63 YPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLP 122
+P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P+ ++ L+KLP
Sbjct: 9 FPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHNSQLPNDYQSLLKLP 65
Query: 123 GIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREEWI 181
GIG AN +L +GF + VD ++ R+ RL GL P + + ++++ + + + E
Sbjct: 66 GIGAYTANAILCFGFREKSACVDANIKRVLLRLFGLDP-NITAKDLQIKANDFLNLNESF 124
Query: 182 YVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 125 NHNQALIDLGALICSP 140
>emb|CAB37765.1| (AJ239654) MutY protein [Helicobacter pylori]
Length = 140
Score = 68.7 bits (165), Expect = 6e-11
Identities = 40/138 (28%), Positives = 78/138 (55%), Gaps = 5/138 (3%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
K +P+++ +A+A +EE+ R L + S+ K + +++ I +++ ++P+ ++ L+K
Sbjct: 7 KAFPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICAKEHNSQLPNDYQSLLK 63
Query: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREE 179
LPGIG AN +L +GF VD +V R+ RL GL P + ++++ + + + E
Sbjct: 64 LPGIGAYTANAILCFGFREKTACVDANVKRVLLRLFGLDP-NIHAKDLQIKANDFLNPNE 122
Query: 180 WIYVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 123 SFNHNQALIDLGALICSP 140
>emb|CAB37757.1| (AJ239646) MutY protein [Helicobacter pylori]
Length = 140
Score = 68.3 bits (164), Expect = 7e-11
Identities = 39/136 (28%), Positives = 78/136 (56%), Gaps = 5/136 (3%)
Query: 63 YPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLP 122
+P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P+ ++ L+KLP
Sbjct: 9 FPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHNSQLPNDYQSLLKLP 65
Query: 123 GIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREEWI 181
GIG AN +L +GF VD +V R+ RL GL P + ++++ + + + E
Sbjct: 66 GIGAYTANAILCFGFREKTACVDANVKRVLLRLFGLDP-NIQAKDLQIKANDFLNLNESF 124
Query: 182 YVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 125 NHNQALIDLGALICSP 140
>emb|CAB37758.1| (AJ239647) MutY protein [Helicobacter pylori]
Length = 140
Score = 68.3 bits (164), Expect = 7e-11
Identities = 39/138 (28%), Positives = 80/138 (57%), Gaps = 5/138 (3%)
Query: 61 KRYPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIK 120
K +P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P+ ++ L+K
Sbjct: 7 KAFPTLKDLANAPLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHDSQLPNDYQSLLK 63
Query: 121 LPGIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREE 179
LPGIG AN +L +GF VD ++ R+ RL GL P + + ++++ + + + E
Sbjct: 64 LPGIGTYTANAILCFGFREKKACVDANIKRVLLRLFGLDP-NITAKDLQIKANDFLNLNE 122
Query: 180 WIYVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 123 SFDHNQALIDLGALICSP 140
>emb|CAB37764.1| (AJ239653) MutY protein [Helicobacter pylori]
Length = 140
Score = 68.3 bits (164), Expect = 7e-11
Identities = 39/136 (28%), Positives = 78/136 (56%), Gaps = 5/136 (3%)
Query: 63 YPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLP 122
+P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P+ ++ L+KLP
Sbjct: 9 FPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHNSQLPNDYQNLLKLP 65
Query: 123 GIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREEWI 181
GIG AN +L +GF VD +V R+ RL GL P + ++++ + + + E
Sbjct: 66 GIGAYTANAILCFGFREKTACVDANVKRVLLRLFGLDP-NIQAKDLQIKANDFLNLNESF 124
Query: 182 YVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 125 NHNQALIDLGALICSP 140
>emb|CAB37768.1| (AJ239657) MutY protein [Helicobacter pylori]
Length = 140
Score = 67.9 bits (163), Expect = 1e-10
Identities = 38/136 (27%), Positives = 80/136 (57%), Gaps = 5/136 (3%)
Query: 63 YPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLP 122
+P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P++++ L+KLP
Sbjct: 9 FPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHNSQLPNEYQSLLKLP 65
Query: 123 GIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREEWI 181
GIG AN +L +GF + VD ++ R RL GL P + + ++++ + + + E
Sbjct: 66 GIGAYTANAILCFGFREKSACVDANIKRTLLRLFGLDP-NITAKDLQIKANDFLNLNESF 124
Query: 182 YVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 125 NHNQALIDLGALICSP 140
>emb|CAB37769.1| (AJ239658) MutY protein [Helicobacter pylori]
Length = 140
Score = 67.9 bits (163), Expect = 1e-10
Identities = 38/136 (27%), Positives = 79/136 (57%), Gaps = 5/136 (3%)
Query: 63 YPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLP 122
+P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P+ ++ L+KLP
Sbjct: 9 FPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHNSQLPNDYQSLLKLP 65
Query: 123 GIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREEWI 181
GIG AN +L +GF + VD ++ R+ RL GL P + ++++ + + + E
Sbjct: 66 GIGAYTANAILCFGFRKKSACVDANIKRVLLRLFGLDP-NIHAKDLQIKANDFLNLNESF 124
Query: 182 YVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 125 NHNQALIDLGALICSP 140
>emb|CAB37774.1| (AJ239663) MutY protein [Helicobacter pylori]
Length = 140
Score = 67.9 bits (163), Expect = 1e-10
Identities = 38/136 (27%), Positives = 79/136 (57%), Gaps = 5/136 (3%)
Query: 63 YPSIEAIASASVEEMQNFLRSLKVGLWRSKGKWIVETSRIILEKYKGRVPDKFEELIKLP 122
+P+++ +A+A +EE+ R L + S+ K + +++ I ++++ ++P+ ++ L+KLP
Sbjct: 9 FPTLKDLANAQLEEVLLLWRGLG---YYSRAKNLKKSAEICVKEHNSQLPNDYQSLLKLP 65
Query: 123 GIGRKCANIVLAYGFGIPAIPVDTHVYRISRRL-GLAPWDASPEEVEERLKELIPREEWI 181
GIG AN +L +GF + VD ++ R+ RL GL P + ++++ + + + E
Sbjct: 66 GIGAYTANAILCFGFREKSACVDANIKRVLLRLFGLDP-NIHAKDLQIKANDFLNLNESF 124
Query: 182 YVNHAMVDHGKSVCRP 197
N A++D G +C P
Sbjct: 125 NHNQALIDLGALICSP 140
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.137 0.412
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82761198
Number of Sequences: 2977
Number of extensions: 3413566
Number of successful extensions: 9535
Number of sequences better than 1.0e-10: 102
Number of HSP's better than 0.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 9357
Number of HSP's gapped (non-prelim): 102
length of query: 222
length of database: 189,106,746
effective HSP length: 53
effective length of query: 169
effective length of database: 157,386,935
effective search space: 26598392015
effective search space used: 26598392015
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 163 (67.9 bits)