BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0462 (PAB0462) DE:CATION EFFLUX SYSTEM PROTEIN (ZINC/CADMIUM) (283 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||H75109 cation efflux system protein (zinc/cadmium) PAB0462 ... 552 e-156 sp|Q57891|Y449_METJA HYPOTHETICAL PROTEIN MJ0449 >gi|2127930|pir... 338 5e-92 pir||F69119 cation efflux system protein (zinc/cadmium) - Methan... 179 4e-44 dbj|BAB04957.1| (AP001511) cation efflux system (zinc/cadmium) [... 174 9e-43 gb|AAC63637.1| (AC005309) unknown protein [Arabidopsis thaliana] 153 2e-36 gi|11499965 conserved hypothetical transmembrane protein [Archae... 152 4e-36 gb|AAG20064.1| (AE005086) cation efflux system protein (zinc/cad... 146 2e-34 pir||F72323 conserved hypothetical protein - Thermotoga maritima... 146 3e-34 dbj|BAB04431.1| (AP001509) cation efflux system [Bacillus halodu... 145 6e-34 pir||C69781 cation efflux system homolog ydfM - Bacillus subtili... 144 1e-33 pir||C69023 conserved hypothetical protein MTH1172 - Methanobact... 138 8e-32 sp|P46348|YEAB_BACSU HYPOTHETICAL 31.8 KD PROTEIN IN GABP-GUAA I... 132 3e-30 gb|AAC44640.1| (U31756) OrfX [Bacillus subtilis] 129 4e-29 pir||D83150 probable transporter PA3963 [imported] - Pseudomonas... 124 1e-27 pir||G72363 cation efflux system protein - Thermotoga maritima (... 117 1e-25 pir||B69772 conserved hypothetical protein ydbO - Bacillus subti... 115 8e-25 pir||H82045 conserved hypothetical protein VC2690 [imported] - V... 114 1e-24 pir||G70477 hypothetical protein aq_2073 - Aquifex aeolicus >gi|... 112 5e-24 sp|Q9ZCC5|P34_RICPR PROTEIN P34 >gi|7467934|pir||A71645 protein ... 112 5e-24 pir||C81369 probable transmembrane transport protein Cj0948c [im... 107 1e-22 pir||E75421 conserved hypothetical protein - Deinococcus radiodu... 106 2e-22 sp|P21559|P34_RICRI PROTEIN P34 >gi|97211|pir||S13095 P34 protei... 105 7e-22 pir||H70941 hypothetical protein Rv2025c - Mycobacterium tubercu... 105 7e-22 sp|P32159|YIIP_ECOLI HYPOTHETICAL 32.9 KD PROTEIN IN CPXA-PFKA I... 104 9e-22 dbj|BAA99362.1| (AP002526) ESTs AU032649(S13048),D47505(S13048) ... 104 9e-22 gb|AAD34683.1|AC006341_11 (AC006341) >F3O9.11 [Arabidopsis thali... 102 4e-21 pir||T00555 hypothetical protein F12L6.11 - Arabidopsis thaliana... 102 6e-21 gb|AAD30224.1|AC007202_6 (AC007202) EST gb|AA404917 comes from t... 102 6e-21 pir||C69612 cation-efflux system membrane protein czcD - Bacillu... 94 1e-18 dbj|BAA19587.1| (D87026) membrane protein [Bacillus stearothermo... 92 9e-18 gi|11499720 conserved hypothetical transmembrane protein [Archae... 88 1e-16 gb|AAB53029.1| (U62055) CzcD [Bacillus subtilis] 88 1e-16 pir||H71078 probable cation efflux system protein czcD - Pyrococ... 87 2e-16 pir||T31797 hypothetical protein R02F11.3 - Caenorhabditis elega... 87 3e-16 sp|P74068|YC63_SYNY3 HYPOTHETICAL 33.3 KD PROTEIN SLL1263 >gi|74... 87 3e-16 pir||T40838 probable transporter - fission yeast (Schizosaccharo... 86 4e-16 sp|P13512|CZCD_ALCEU COBALT-ZINC-CADMIUM RESISTANCE PROTEIN CZCD... 84 2e-15 sp|P94178|CZCD_ALCSP CATION EFFLUX SYSTEM PROTEIN CZCD >gi|21209... 84 2e-15 sp|P75757|YBGR_ECOLI HYPOTHETICAL 34.7 KDA PROTEIN IN PNUC-AROG ... 81 1e-14 pir||E70392 cation efflux system (czcD-like) - Aquifex aeolicus ... 81 2e-14 pir||T16470 hypothetical protein F56C9.3 - Caenorhabditis elegan... 78 1e-13 pir||E81321 probable cation transport protein Cj1163c [imported]... 77 3e-13 pir||C83595 probable cation efflux system protein PA0397 [import... 77 3e-13 pir||T46028 hypothetical protein T10K17.270 - Arabidopsis thalia... 75 8e-13 pir||T16640 hypothetical protein PDB1.1 - Caenorhabditis elegans... 75 1e-12 pir||T44365 cation-efflux system membrane protein homolog [impor... 75 1e-12 gb|AAF26917.1|AF210843_14 (AF210843) putative transport protein ... 74 2e-12 pir||G82752 cobalt-zinc-cadmium resistance protein XF0866 [impor... 74 2e-12 pir||A75437 cation efflux system protein - Deinococcus radiodura... 74 2e-12 pir||D33830 cation efflux system membrane protein czcD - Alcalig... 71 1e-11 gb|AAC32485.1| (AF044951) transport protein [Staphylococcus aureus] 69 4e-11 pir||T35276 probable efflux protein - Streptomyces coelicolor >g... 68 1e-10 >pir||H75109 cation efflux system protein (zinc/cadmium) PAB0462 - Pyrococcus abyssi (strain Orsay) >gi|5458104|emb|CAB49593.1| (AJ248285) CATION EFFLUX SYSTEM PROTEIN (ZINC/CADMIUM) [Pyrococcus abyssi] Length = 283 Score = 552 bits (1406), Expect = e-156 Identities = 283/283 (100%), Positives = 283/283 (100%) Query: 1 MEEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKK 60 MEEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKK Sbjct: 1 MEEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKK 60 Query: 61 PPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSI 120 PPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSI Sbjct: 61 PPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSI 120 Query: 121 LVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFV 180 LVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFV Sbjct: 121 LVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFV 180 Query: 181 VALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHV 240 VALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHV Sbjct: 181 VALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHV 240 Query: 241 ELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVDIRE 283 ELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVDIRE Sbjct: 241 ELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVDIRE 283 >sp|Q57891|Y449_METJA HYPOTHETICAL PROTEIN MJ0449 >gi|2127930|pir||A64356 gabP 5'-region hypothetical protein homolog MJ0449 - Methanococcus jannaschii >gi|1591153|gb|AAB98438.1| (U67496) hypothetical transmembrane protein yeaB [Methanococcus jannaschii] Length = 283 Score = 338 bits (857), Expect = 5e-92 Identities = 160/281 (56%), Positives = 219/281 (76%) Query: 1 MEEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKK 60 M E KPLI+SI+GN +LG++K+++G SI+LISDGIHSLSD +TS++G +GVK++ K Sbjct: 1 MREVEKPLILSIVGNILLGLIKIIIGYVYSSISLISDGIHSLSDVITSIIGIIGVKIASK 60 Query: 61 PPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSI 120 PPDESHP+GHSRFE LF+FF+G L AYEI + ++ R++ E I + MV VA+LSI Sbjct: 61 PPDESHPYGHSRFECLFSFFIGLALFFTAYEIGKFAVERIIYGEVIEVNAIMVGVAILSI 120 Query: 121 LVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFV 180 +VKELMTRY+L VGK+L+++++IADAYHHRSD LS++VVLVG LQ+ GI++GDA+AG + Sbjct: 121 VVKELMTRYSLFVGKKLNSQVLIADAYHHRSDALSSVVVLVGLLLQKFGIYYGDAIAGII 180 Query: 181 VALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHV 240 VAL + KV +I L N++YLTGRAPP + + IE+ A +VD V+GVHD++AHYVG ++HV Sbjct: 181 VALMIAKVAFDICLTNIDYLTGRAPPKKFFELIEKEALNVDKVIGVHDIKAHYVGPRIHV 240 Query: 241 ELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVDI 281 ELH+EV S K+ HDI VK ++ESL V A++HVDI Sbjct: 241 ELHVEVPSNISAKEMHDIEVAVKNRLESLENVERAYVHVDI 281 >pir||F69119 cation efflux system protein (zinc/cadmium) - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2623026|gb|AAB86353.1| (AE000941) cation efflux system protein (zinc/cadmium) [Methanobacterium thermoautotrophicum] Length = 298 Score = 179 bits (449), Expect = 4e-44 Identities = 92/270 (34%), Positives = 159/270 (58%), Gaps = 8/270 (2%) Query: 14 GNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRF 73 GN +L + +VG+ + S+AL+++ H+LSD +TSV+ ++G ++ ++PPD HP+GH R Sbjct: 20 GNVLLTSLNFLVGISSGSVALVAEAAHTLSDVLTSVITYIGFRIGQRPPDRQHPYGHGRA 79 Query: 74 EPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTP---TMVIVALLSILVKELMTRYA 130 E L + L +++YEI ++ ++ + L P T ++A I+ MT Y Sbjct: 80 EALVGLVVVVFLGIISYEILSEAYRKLF----LELAPPDYTAALMAGFGIIANIAMTTYI 135 Query: 131 LSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVGV 190 +G+R+++ I+ADA H + D+ S I +++G LG+ F D L ++A+ V K Sbjct: 136 RRIGERINSPAIVADAQHQKVDIFSCIAIMLGVAGSHLGLRFLDPLVAVIIAVLVLKTAF 195 Query: 191 EILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPET 250 ++ ENVN + G P E+ + IE+ A SVDGV G+H++R ++ G V+LHIEV + Sbjct: 196 DVGRENVNNILGAVPSPEIMEDIEKSAMSVDGVKGLHEVRINHFGPYASVDLHIEVDGDM 255 Query: 251 SLKKAHDISEEVKRKV-ESLPEVSEAFIHV 279 L+ AH I+ +V+R+V E + + +HV Sbjct: 256 MLRDAHRIAHDVERRVIEDIDIIKIVNVHV 285 >dbj|BAB04957.1| (AP001511) cation efflux system (zinc/cadmium) [Bacillus halodurans] Length = 300 Score = 174 bits (437), Expect = 9e-43 Identities = 97/279 (34%), Positives = 160/279 (56%), Gaps = 10/279 (3%) Query: 10 VSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFG 69 + I+ N L +K +VG+ S ALI+D +HS SD V+SVV +GV+ +K PPDE HP+G Sbjct: 17 IGIVANLGLAAMKAIVGMIANSKALIADAVHSASDVVSSVVVLIGVRAAKMPPDEDHPYG 76 Query: 70 HSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVA-LLSILVKELMTR 128 H + E + + + LL +V +EIA + E + + T+ I A L+SI VKE + R Sbjct: 77 HGKAESVASIIVAVLLFIVGFEIAVSAFQSFF--EPVEVPRTLAIYAVLISIFVKEGLFR 134 Query: 129 YALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLG-------IWFGDALAGFVV 181 Y +GK+ + ++ DA+HHRSDVLS+ L+G G LG + +GDA+A VV Sbjct: 135 YKHYLGKKFKSDALVTDAWHHRSDVLSSFAALLGIGAAILGGYLHIQWLVYGDAVASAVV 194 Query: 182 ALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVE 241 A+ +GK+ ++ + ++ E ++ E A+SVDGV+ + A G + ++ Sbjct: 195 AVLIGKMAWDLGNQAIHNTLDHVLHDEDTVEMREAAKSVDGVMNLDAFHAREHGHYVIID 254 Query: 242 LHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 + I V+P +++ H I++ VK ++ P V + F+HV+ Sbjct: 255 IKIAVNPRMTVEDGHTIAKAVKERLMLEPNVHDVFVHVN 293 >gb|AAC63637.1| (AC005309) unknown protein [Arabidopsis thaliana] Length = 483 Score = 153 bits (383), Expect = 2e-36 Identities = 96/298 (32%), Positives = 155/298 (51%), Gaps = 20/298 (6%) Query: 2 EEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKP 61 EE K + + + L V K + G S A+I+D HS+SD V S V V + + P Sbjct: 71 EEGEKIFRLGLTADIGLSVAKALTGYLCGSTAIIADAAHSVSDVVLSGVALVSYRAANVP 130 Query: 62 PDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMV-------- 113 D+ HP+GH +FE L A + +L+ IA +L L + P ++ Sbjct: 131 KDKEHPYGHGKFETLGALGISAMLLATGSGIAWHALD--LLSIALSAAPEVIHSGHHHGI 188 Query: 114 ---------IVALLSILVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFG 164 V + SI +KE + G++ + +++A+A+HHRSD +S++V LVG G Sbjct: 189 DMNHPILALTVTIASISIKEGLYWITKRAGEKQGSGLMMANAWHHRSDAISSLVALVGVG 248 Query: 165 LQRLGIWFGDALAGFVVALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVL 224 LG+ F D LAG VV+ + G++ +++ L A P + + I + V+GV Sbjct: 249 GSILGVNFLDPLAGLVVSTMIVNAGLKTGHQSILELVDAAIPAQQLEPIRQTILQVEGVK 308 Query: 225 GVHDLRAHYVGTKLHVELHIEVSPETSLKKAHDISEEVKRKVE-SLPEVSEAFIHVDI 281 G H LR G+ L++++HI V P +S+ AH++ E V+R++ + PEVSE FIH+ I Sbjct: 309 GCHRLRGRRAGSSLYLDVHIVVDPFSSVSVAHEVGEYVRRQINLNHPEVSEVFIHIGI 366 >gi|11499965 conserved hypothetical transmembrane protein [Archaeoglobus fulgidus] >gi|7483269|pir||D69548 conserved hypothetical transmembrane protein AF2388 - Archaeoglobus fulgidus >gi|2650701|gb|AAB91271.1| (AE001111) conserved hypothetical transmembrane protein [Archaeoglobus fulgidus] Length = 384 Score = 152 bits (381), Expect = 4e-36 Identities = 85/276 (30%), Positives = 150/276 (53%), Gaps = 5/276 (1%) Query: 1 MEEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKK 60 M+E L+ +S N VL +K+ G+F S ALI+DG+HSL D + SV+ ++G+K++++ Sbjct: 1 MDEALRAGKISAFANVVLTALKVAAGIFANSTALIADGVHSLVDVLGSVLVWLGIKVAER 60 Query: 61 PPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSI 120 P D SHP+GH + E L +G ++I+ + I +++ +++ V VA+LS Sbjct: 61 PADASHPYGHFKAESLAEMAVGLIIILSSLLIMHEAISSVINASVPTFELYAVAVAMLSA 120 Query: 121 LVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFV 180 + EL+ RY + VG + + +IA+ H R DVLS++ V+VGF G W+ D++ Sbjct: 121 VANELLARYKIRVGLKTRSTSLIAEGKHSRVDVLSSLAVVVGFFFVYFGYWWADSVVAIA 180 Query: 181 VALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHV 240 +++ + ++G +L +++ L R E+ K+ V +DGV V + V Sbjct: 181 ISVVILQIGGSVLKNSIDVLMDRVDE-ELALKVRSVIEKIDGVKSVDFIGTRGTMKSRVV 239 Query: 241 ELHIEV----SPETSLKKAHDISEEVKRKVESLPEV 272 E+H+ V ET +ISEE+K ++ + V Sbjct: 240 EVHLTVDAGMDAETIAALQREISEEIKERIPGVVNV 275 >gb|AAG20064.1| (AE005086) cation efflux system protein (zinc/cadmium); Cef [Halobacterium sp. NRC-1] Length = 299 Score = 146 bits (366), Expect = 2e-34 Identities = 96/262 (36%), Positives = 142/262 (53%), Gaps = 17/262 (6%) Query: 31 SIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAFFMGELLIVVAY 90 S+A+ S+ I+SL+D S+V G+ L+ +PPD HP GH R EP + +VVA Sbjct: 34 SLAVGSEAINSLADVAYSLVVLGGLYLTTQPPDFKHPHGHERIEPFVS-------LVVAL 86 Query: 91 EIARDSLGRMLSRETIRL-------TPTMVIVALL--SILVKELMTRYALSVGKRLDNKI 141 + G +L + T + TP + V +L + + K + RY L V + Sbjct: 87 GVLAAG-GAVLWQATTTVAAGDYGPTPGLPAVGVLVGTAVAKYALYRYVLGVAADHRSPA 145 Query: 142 IIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEILLENVNYLT 201 + A A +R+D+L+ LVG G D LA FVVA + G EI+ +NVNYL Sbjct: 146 LRATALDNRNDILTASAALVGVLGSATGYPVLDPLAAFVVAAGILHTGYEIVRDNVNYLV 205 Query: 202 GRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPETSLKKAHDISEE 261 G APP ++ ++I A V G HD+ AHYVG ++ V LH+EV E +L +AHDI + Sbjct: 206 GAAPPADLREQILGRALDNPDVEGAHDVVAHYVGPEIDVSLHVEVEGEMTLHEAHDIETD 265 Query: 262 VKRKVESLPEVSEAFIHVDIRE 283 + +ES+PEV + F+HVD +E Sbjct: 266 LILDLESIPEVDDVFVHVDPKE 287 >pir||F72323 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981410|gb|AAD35957.1|AE001753_13 (AE001753) conserved hypothetical protein [Thermotoga maritima] Length = 306 Score = 146 bits (365), Expect = 3e-34 Identities = 87/284 (30%), Positives = 158/284 (55%), Gaps = 5/284 (1%) Query: 2 EEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKP 61 EE K + I+GNTVL V+K++VGL S A+++DGI + +D TS+V + ++S KP Sbjct: 5 EEIKKGAWIGILGNTVLAVLKILVGLLTGSYAILADGIDTSTDIFTSLVILLSSRISGKP 64 Query: 62 PDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRE-TIRLTPTMVIVALLSI 120 PDE+HP+GH R E + + + ++ + +S+ R++ +E ++ LT T IV +S+ Sbjct: 65 PDETHPYGHERAETIASKIISFVMFYAGASLLVESVKRLVKQEFSLELTLTAFIVVGISV 124 Query: 121 LVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGF-GLQRLGIWFGDALAGF 179 K + Y LS+GKRL + I+DA + R+D++ + VL G ++ G W+ D+L Sbjct: 125 AGKTFLFLYKLSLGKRLKSSATISDALNMRNDIMISGTVLAGMVAMKTFGWWWLDSLLAI 184 Query: 180 VVALFVGKVGVEILLENVNYLTG--RAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTK 237 V++ + + + E L + ++ I V V H +R VGTK Sbjct: 185 FVSIMILRTSFSVFYEAAYELMDGMKRTELDMYDDIFAVLERFPNVHNPHRVRIRRVGTK 244 Query: 238 LHVELHIEVSPETSLKKAHDISEEVKRK-VESLPEVSEAFIHVD 280 +E+ IEV + S+K AH+++ +++++ ++ ++ + IHV+ Sbjct: 245 YFIEMDIEVDGKMSVKDAHELTVKIRKEMLKRRDDIEDVTIHVE 288 >dbj|BAB04431.1| (AP001509) cation efflux system [Bacillus halodurans] Length = 307 Score = 145 bits (362), Expect = 6e-34 Identities = 84/279 (30%), Positives = 147/279 (52%), Gaps = 8/279 (2%) Query: 10 VSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFG 69 V II N +L ++K V+G + S ALI+D HS SD S+ G++ +KKPPD HP+G Sbjct: 14 VGIIVNGLLALMKGVIGWLSGSRALIADAAHSASDVAGSIAVLAGLRTAKKPPDADHPYG 73 Query: 70 HSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRY 129 H + E + + LLIVV EIA S + ++ + SI++KE++ +Y Sbjct: 74 HGKAENVATIIVAILLIVVGVEIAISSTKVFVGEMPSAPKGIALVAIIASIIIKEVLFQY 133 Query: 130 ALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFG-------DALAGFVVA 182 + K++++ ++A+A+HHRSD LS+I +G +G F D +AG +V+ Sbjct: 134 KYRLAKKINSSALLAEAWHHRSDALSSIAAFIGVFGAMVGQHFNYPILVYLDPVAGLIVS 193 Query: 183 LFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVEL 242 L V K+G + E+ + + + E K ++GV + +L A G + V++ Sbjct: 194 LIVIKIGFSLAKESSSIMMEQVLDPEKTKPFIRTVSKIEGVKRIDELLARTHGHYIVVDI 253 Query: 243 HIEVSPETSLKKAHDISEEVKRK-VESLPEVSEAFIHVD 280 + V P S+++ H IS+ VK+ + + + F+H++ Sbjct: 254 KVGVDPNLSVEEGHRISKRVKKALLANHNHIKRVFVHIN 292 >pir||C69781 cation efflux system homolog ydfM - Bacillus subtilis >gi|1881354|dbj|BAA19381.1| (AB001488) FUNCTION UNKNOWN, SIMILAR PRODUCT IN SYNECHOCYSTIS AND E. COLI. [Bacillus subtilis] >gi|2632847|emb|CAB12354.1| (Z99106) similar to cation efflux system [Bacillus subtilis] Length = 297 Score = 144 bits (360), Expect = 1e-33 Identities = 78/283 (27%), Positives = 158/283 (55%), Gaps = 9/283 (3%) Query: 6 KPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDES 65 K ++++I N +L K+ GL S A+ +DGIHS +D V S+ + +S KPPD+ Sbjct: 11 KVALIALIANLILMAGKVFFGLVGDSEAVFADGIHSAADVVASIAVLAVIGISNKPPDQD 70 Query: 66 HPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKEL 125 HPFGH + E + +G +L++V+ I +++ + ++ + + AL+S + KE+ Sbjct: 71 HPFGHGKAEVISEAIVGIILVIVSVYILIEAILSFVKGPSVP-QYSALFAALISYVAKEI 129 Query: 126 MTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLG-------IWFGDALAG 178 + RY++ GK+ ++K IIA AY H+ D+++++ +G L +G + + DA+A Sbjct: 130 LYRYSIKQGKKWNSKAIIAIAYDHKGDIVASLAAFIGVLLAIIGNSRGWSYLLYADAIAS 189 Query: 179 FVVALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKL 238 +VA + K+ +E++ +V L ++ E+ ++ + V D V + +RA G Sbjct: 190 AIVAYLIFKISMELIRPSVGVLMEKSVDPELIEEYKAVIFQCDQVKRIDRIRAREHGHYK 249 Query: 239 HVELHIEVSPETSLKKAHDISEEVKRKVE-SLPEVSEAFIHVD 280 +++ + + + ++K+ HDI+ E++ +++ +V E IHV+ Sbjct: 250 LLDVRLSLDHDLTIKQGHDIAREIRNEIKRQFSDVEEVLIHVN 292 >pir||C69023 conserved hypothetical protein MTH1172 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622279|gb|AAB85661.1| (AE000886) possible cation transporter [Methanobacterium thermoautotrophicum] Length = 407 Score = 138 bits (344), Expect = 8e-32 Identities = 83/264 (31%), Positives = 144/264 (54%), Gaps = 2/264 (0%) Query: 11 SIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGH 70 S+I N +L V+K G + +IALI+D IHS +D +S F+G+KLS++ PDE P+G+ Sbjct: 19 SVIINMILVVIKGFTGYLSGNIALIADAIHSFADVFSSAAVFIGLKLSQRKPDELFPYGY 78 Query: 71 SRFEPLFAFFMGELLIVVAYEIARDSLGRMLS-RETIRLTPTMVIVALLSILVKELMTRY 129 R E L + + L+I+ EI DS+ +L+ + + + V+L+SI V + Y Sbjct: 79 HRIETLVSLLVSVLIIITGLEITWDSIIYILNPASEVSMATASLAVSLISIGVSYAIAFY 138 Query: 130 ALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVG 189 + VG+R+ + ++ D H DV+S+I+V +G + +G+ +AG ++++ + +G Sbjct: 139 KVRVGRRIGSTALLNDGKHSYVDVISSILVFLGILGEYMGLHGFQGIAGVIISVVIIYIG 198 Query: 190 VEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPE 249 + + +V L + + I++ SV GV GVHD+R G L ELHIE+ Sbjct: 199 IRLAKYDVLTLLDACIDRDSIEVIKKTVLSVPGVEGVHDIRIRRSGPYLFGELHIELERG 258 Query: 250 TSLKKAHDISEEVKRKV-ESLPEV 272 + K I ++ +V E LP + Sbjct: 259 LPVDKIEGIISQINSRVKEVLPSI 282 >sp|P46348|YEAB_BACSU HYPOTHETICAL 31.8 KD PROTEIN IN GABP-GUAA INTERGENIC REGION (ORFX) >gi|7447652|pir||B69791 cation efflux system membrane protein homolog yeaB - Bacillus subtilis >gi|1708640|gb|AAB62307.1| (U51115) YeaB [Bacillus subtilis] >gi|2632945|emb|CAB12451.1| (Z99107) alternate gene name: ydxT~similar to cation efflux system membrane protein [Bacillus subtilis] Length = 290 Score = 132 bits (330), Expect = 3e-30 Identities = 71/274 (25%), Positives = 153/274 (54%), Gaps = 5/274 (1%) Query: 9 IVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPF 68 +VSI VL +KL++G S AL +DG+++ +D + SV +G+++S+KPPDE HP+ Sbjct: 15 LVSIAAYLVLSAIKLIIGYLFHSEALTADGLNNTTDIIASVAVLIGLRISQKPPDEDHPY 74 Query: 69 GHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVI--VALLSILVKELM 126 GH R E + + +++VV ++ + + S + + TP M+ A ++ ++ Sbjct: 75 GHFRAETIASLIASFIMMVVGLQVLFSAGESIFSAK--QETPDMIAAWTAAGGAVLMLIV 132 Query: 127 TRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVG 186 RY + K++ ++ ++A A ++SD +I +G + + + D + FV+ L + Sbjct: 133 YRYNKRLAKKVKSQALLAAAADNKSDAFVSIGTFIGIVAAQFHLAWIDTVTAFVIGLLIC 192 Query: 187 KVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEV 246 K +I E+ + LT ++ ++ + GV + D++A Y+G+ +HV++ +EV Sbjct: 193 KTAWDIFKESSHSLTDGFDIKDI-SAYKQTIEKISGVSRLKDIKARYLGSTVHVDVVVEV 251 Query: 247 SPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 S + ++ ++HDI+ E++R+++ + + +H++ Sbjct: 252 SADLNITESHDIANEIERRMKEEHAIDYSHVHME 285 >gb|AAC44640.1| (U31756) OrfX [Bacillus subtilis] Length = 276 Score = 129 bits (321), Expect = 4e-29 Identities = 70/261 (26%), Positives = 147/261 (55%), Gaps = 5/261 (1%) Query: 9 IVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPF 68 +VSI VL +KL++G S AL +DG+++ +D + SV +G+++S+KPPDE HP+ Sbjct: 15 LVSIAAYLVLSAIKLIIGYLFHSEALTADGLNNTTDIIASVAVLIGLRISQKPPDEDHPY 74 Query: 69 GHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVI--VALLSILVKELM 126 GH R E + + +++VV ++ + + S + + TP M+ A ++ ++ Sbjct: 75 GHFRAETIASLIASFIMMVVGLQVLFSAGESIFSAK--QETPDMIAAWTAAGGAVLMLIV 132 Query: 127 TRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVG 186 RY + K++ ++ ++A A ++SD +I +G + + + D + FV+ L + Sbjct: 133 YRYNKRLAKKVKSQALLAAAADNKSDAFVSIGTFIGIVAAQFHLAWIDTVTAFVIGLLIC 192 Query: 187 KVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEV 246 K +I E+ + LT ++ ++ + GV + D++A Y+G+ +HV++ +EV Sbjct: 193 KTAWDIFKESSHSLTDGFDIKDI-SAYKQTIEKISGVSRLKDIKARYLGSTVHVDVVVEV 251 Query: 247 SPETSLKKAHDISEEVKRKVE 267 S + ++ ++HDI+ E++R+++ Sbjct: 252 SADLNITESHDIANEIERRMK 272 >pir||D83150 probable transporter PA3963 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950152|gb|AAG07350.1|AE004814_5 (AE004814) probable transporter [Pseudomonas aeruginosa] Length = 298 Score = 124 bits (309), Expect = 1e-27 Identities = 77/266 (28%), Positives = 135/266 (49%) Query: 18 LGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLF 77 L + K + + S++L++ SL D+ S++ + V S +P D+ H +GH + E L Sbjct: 25 LVIGKAIAWWLSGSVSLLAGLTDSLLDSAASLLNLLAVHYSLRPADDDHRYGHGKAEALA 84 Query: 78 AFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGKRL 137 + A +A ++ ++ + + + V LLS+L+ L+ + V +R Sbjct: 85 GLAQAMFIGASAVLVAIQAVEQLRDPQPLGAATWGIAVMLLSLLLTALLLAFQTHVIRRT 144 Query: 138 DNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEILLENV 197 + I AD+ H+RSD+L +LV L R G D L G +AL++ ++I E+V Sbjct: 145 GSTAIRADSLHYRSDLLLNASILVALLLARYGWPQSDGLFGLGIALYILWSALQIARESV 204 Query: 198 NYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPETSLKKAHD 257 + L R P ++ +++ E+A SV GVLG HD+R G V+LH+E+ E SL AH Sbjct: 205 SILMDRELPTDISERMRELACSVPGVLGAHDVRTRISGNHWFVQLHLELPGELSLSVAHA 264 Query: 258 ISEEVKRKVESLPEVSEAFIHVDIRE 283 +++ ++ +E IH D +E Sbjct: 265 LTDRAVLAIKREYPKAEVLIHADPQE 290 >pir||G72363 cation efflux system protein - Thermotoga maritima (strain MSB8) >gi|4981052|gb|AAD35623.1|AE001729_3 (AE001729) cation efflux system protein [Thermotoga maritima] Length = 284 Score = 117 bits (291), Expect = 1e-25 Identities = 79/265 (29%), Positives = 148/265 (55%), Gaps = 9/265 (3%) Query: 6 KPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDES 65 K L+ SI N ++ + ++V GL + S+AL+ D +H+ SDT++ + F+ +K+S+KP ++ Sbjct: 3 KKLLFSIWLNAIITLSEVVGGLISGSLALLGDSLHNFSDTMSLLGSFIAMKISEKPKNKK 62 Query: 66 HPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKEL 125 + FG+ R E + AF + VV+ + +++ R+LS T+ T +++V+ + + Sbjct: 63 YTFGYRRSEIIVAFLNSVSIFVVSTLVVIEAVKRLLSPATVH-TSVLLLVSSIGLAANFF 121 Query: 126 MTRYALSVGKRLDNKIIIADAYHHR-SDVLSTIVVLVGFGLQRL-GIWFGDALAGFVVAL 183 + K N + AY H +D LS+I+V++G R+ I++ D + FV+AL Sbjct: 122 SVILLHTHSKESMN---VRSAYLHLIADTLSSILVVLGAVFMRVWKIYWLDPVLAFVIAL 178 Query: 184 FVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTK-LHVEL 242 ++ K EI+ E++ L +P + +KI+E ++GV H A VG K +H E Sbjct: 179 YMFKEAYEIVKESLEILMEASPNLDF-EKIKEEIEKIEGVRNAHHFHAWRVGEKEIHFEC 237 Query: 243 HIEVSPETSLKKAHDISEEVKRKVE 267 H+EV LK A I +E++++++ Sbjct: 238 HVEVD-NMELKDAQKIIDEIEKRLK 261 >pir||B69772 conserved hypothetical protein ydbO - Bacillus subtilis >gi|1881264|dbj|BAA19291.1| (AB001488) FUNCTION UNKNOWN, SIMILAR PRODUCT IN B. SUBTILIS AND E. COLI. [Bacillus subtilis] >gi|2632754|emb|CAB12261.1| (Z99106) similar to hypothetical proteins [Bacillus subtilis] Length = 290 Score = 115 bits (284), Expect = 8e-25 Identities = 72/280 (25%), Positives = 147/280 (51%), Gaps = 11/280 (3%) Query: 6 KPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDES 65 K +++I +L VVKLV+G+ S AL +DG+++ +D V SV +G+++S++P D Sbjct: 12 KGALLNIFAYVILAVVKLVIGILYHSEALRADGLNNGTDIVASVAVLIGLRISQRPADSD 71 Query: 66 HPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVI--VALLSILVK 123 HP+GH R E + + +++ V E+ G+ ++ T TP ++ AL S + Sbjct: 72 HPYGHYRAETISSLVASFIMMAVGIEVLIGG-GKAIAGGTTE-TPNLIAAWTALGSAVFM 129 Query: 124 ELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVAL 183 + Y + + + ++A A RSD + +G +L + + D + F++ + Sbjct: 130 YGIYLYNKRLAASIKSSALMAAAKDSRSDAFVSAGAFIGVFSSQLKLPWVDPVTAFIIGI 189 Query: 184 FVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVH---DLRAHYVGTKLHV 240 + K +I + + LT K +E ++V + VH D++A Y+G+ +H+ Sbjct: 190 IICKTAWDIFKDASHSLTDGFH----LKDLEPYKQTVGRIENVHRLKDVKARYLGSTVHI 245 Query: 241 ELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 E+ I V P+ ++++ H +++EV+ K++ +V+ +HV+ Sbjct: 246 EMVITVDPKLTVEEGHGVADEVEDKIKHEHDVTHVHVHVE 285 >pir||H82045 conserved hypothetical protein VC2690 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657285|gb|AAF95831.1| (AE004334) conserved hypothetical protein [Vibrio cholerae] Length = 302 Score = 114 bits (282), Expect = 1e-24 Identities = 71/265 (26%), Positives = 130/265 (48%) Query: 16 TVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEP 75 ++L VVK+ S++L++ I S+ D SVV + ++ + +P D H FGH + E Sbjct: 22 SLLLVVKVAAWWVTGSVSLLASLIDSVLDIAASVVNLIVLRFALQPADHEHAFGHGKAES 81 Query: 76 LFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGK 135 L A + A + + + R + + V+ ++ILV + + V + Sbjct: 82 LAALAQAMFISGSACFLILNGVDRFFRPHELNAPELGIYVSAIAILVTFGLVLFQRYVVR 141 Query: 136 RLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEILLE 195 + ++ I AD+ H++SD+L ++V GL G+ DA+ + L++ +++ + Sbjct: 142 KTGSQAIAADSLHYQSDLLMNAAIMVALGLSWWGLGQADAIFAIGIGLYILFSAFKMVHD 201 Query: 196 NVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPETSLKKA 255 V L R P E ++I + SV GV+G+H LR G ++LH+E+ SL +A Sbjct: 202 AVQTLLDRKLPDEELEQIHAICLSVAGVIGMHQLRTRMSGPVRFIQLHLELDDNISLLEA 261 Query: 256 HDISEEVKRKVESLPEVSEAFIHVD 280 H IS+ V+ K+ ++ IH D Sbjct: 262 HQISDRVEDKLREHFVGADVLIHQD 286 >pir||G70477 hypothetical protein aq_2073 - Aquifex aeolicus >gi|2984294|gb|AAC07818.1| (AE000771) putative protein [Aquifex aeolicus] Length = 385 Score = 112 bits (277), Expect = 5e-24 Identities = 78/273 (28%), Positives = 139/273 (50%), Gaps = 5/273 (1%) Query: 9 IVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPF 68 +VS N ++KLV GL S++LI D IHSLSD S++ F+ +K S + E P+ Sbjct: 8 LVSFGFNIFQSLIKLVGGLLTGSLSLIGDAIHSLSDATASLIAFLSIKFS-EIKSERFPY 66 Query: 69 GHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTR 128 G + E + A + L+ A+EI + +L ++ L P + V +LS+++ ++ Sbjct: 67 GLYKLENIGAIVIAFFLLFTAWEIIQRALKGEININFENL-PIGIGVTVLSLVLSLTLSF 125 Query: 129 YALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKV 188 GK+L++ +IAD+YH +D S+ +VL+ GI + VAL + Sbjct: 126 LERRAGKKLNSPTLIADSYHTLTDAFSSFLVLISLSSYYFGINI-ERYVAVAVALIIVYT 184 Query: 189 GVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSP 248 E+L E + + + E +KI+ + S V V L G +L ++ I ++ Sbjct: 185 AFELLKEQIGAILDISADKETVEKIKRIILSFPEVSEVKRLLVRNAGGRLFIDAVITINT 244 Query: 249 ETSLKKAHDISEEVKRKV-ESLPEVSEAFIHVD 280 + + K+H I++E++RK+ + +P V FIH + Sbjct: 245 DDFI-KSHAIADEIERKIMKEIPNVDMVFIHYE 276 >sp|Q9ZCC5|P34_RICPR PROTEIN P34 >gi|7467934|pir||A71645 protein p34 (p34) RP832 - Rickettsia prowazekii >gi|3861358|emb|CAA15257.1| (AJ235273) PROTEIN P34 (p34) [Rickettsia prowazekii] Length = 300 Score = 112 bits (277), Expect = 5e-24 Identities = 65/272 (23%), Positives = 131/272 (47%), Gaps = 3/272 (1%) Query: 10 VSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFG 69 +S+ ++ ++KL + S ++++ I S+ D +S + V ++ + +PPD H FG Sbjct: 15 LSVTTALIILIIKLYAWVVTSSQSILASLIDSMLDITSSFINLVALRFALQPPDHYHRFG 74 Query: 70 HSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRY 129 H + + L F A+ + S+ + + I+ L + + ++ Y Sbjct: 75 HEKMQDLTIFSQSIFFFASAFFVGFASVKSLFIKTKPENISDGTIIMYLCMFLTIILVLY 134 Query: 130 ALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVG 189 V K+ ++I+ AD H+ +D+L+ ++V++ L WF D L G V++L++ Sbjct: 135 QTYVIKKTGSEIVKADKLHYFTDLLTNVIVIISINLSDY-FWFVDPLFGVVISLYIFHSS 193 Query: 190 VEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPE 249 + + L P + +KI + + GV G+H+++ Y K ++ H+E+ Sbjct: 194 YSLFKKAFKNLVDHELPEQDRQKIISIVNNHSGVKGMHEMKTRYAAQKAFIQCHLEMDGN 253 Query: 250 TSLKKAHDISEEVKRKV-ESLPEVSEAFIHVD 280 SL AH IS+E+ ++ + PE +E IH D Sbjct: 254 ISLYSAHKISDEIAFEILQKFPE-AEIIIHQD 284 >pir||C81369 probable transmembrane transport protein Cj0948c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968385|emb|CAB73205.1| (AL139076) putative transmembrane transport protein [Campylobacter jejuni] Length = 295 Score = 107 bits (265), Expect = 1e-22 Identities = 76/285 (26%), Positives = 144/285 (49%), Gaps = 7/285 (2%) Query: 1 MEEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKK 60 M + K +V+ + VL +VK +VGL + S+A++S I SL D S F+ +K S + Sbjct: 1 MSLQKKATLVASLCAIVLALVKFIVGLTSGSVAVLSSAIDSLMDFAISAFNFLALKKSSQ 60 Query: 61 PPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSI 120 +E++ FG S+ E L G ++ V I +S+ ++ +E I+ + + V + ++ Sbjct: 61 KANENYNFGFSKIEALMGLLEGVFIVGVGIFIFYESILKIYYKEEIKDLNSSIYVMIFAL 120 Query: 121 LVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLS---TIVVLVGFGLQRLGIWFGDALA 177 ++ + + V K+ + II +DA H+++D L+ T+ LV L I DA+ Sbjct: 121 IMTFFLVLFLNYVAKKTKSLIIESDALHYKTDCLTNACTLGALVLIYFTNLHII--DAIF 178 Query: 178 GFVVALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTK 237 G V++L+ +I+ + + +L A P E KI + + ++ H+L+ + Sbjct: 179 GIVISLYTAFSAFKIIKKALAFLMDEALPKEQVDKICTLISNNPEIISYHELKTRKTPSC 238 Query: 238 LHVELHIEVSPETSLKKAHDISEEVKRKVESL--PEVSEAFIHVD 280 ++ +H+ P SL AH IS+E++ V + E + IH+D Sbjct: 239 NYLSVHLVFCPIISLLNAHKISDEIEEGVRKMFENEKWDIQIHLD 283 >pir||E75421 conserved hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6458976|gb|AAF10804.1|AE001971_4 (AE001971) conserved hypothetical protein [Deinococcus radiodurans] Length = 317 Score = 106 bits (263), Expect = 2e-22 Identities = 78/282 (27%), Positives = 140/282 (48%), Gaps = 11/282 (3%) Query: 7 PLIVSIIGNTVLGVVKLVVGLFNL------SIALISDGIHSLSDTVTSVVGFVGVKLSKK 60 P+ V+ IG +GV LV+GL L S+AL SD + S+ + V++ + + ++ + Sbjct: 26 PVRVAAIG---VGVALLVLGLKFLAYRLTGSVALFSDALESIINVVSAGGALLALWVAAR 82 Query: 61 PPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSI 120 P D SHP+GH++ E L A G L+++ A I R ++ + + + V + + Sbjct: 83 PADASHPYGHTKAEYLSAVVEGVLIVLAALSILRVAVPELSHPRAVDAPWLGLGVNMGAS 142 Query: 121 LVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIW-FGDALAGF 179 ++ + L +G+ + +IAD H SDV++++ VL+G L RL W D L Sbjct: 143 VINLVWANVLLRIGQASRSPALIADGKHVMSDVVTSVGVLIGVVLARLTGWHILDPLLAL 202 Query: 180 VVALFVGKVGVEILLENV-NYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKL 238 +VAL + G +L +V + P+ + ++ G L +HDLR + G Sbjct: 203 LVALNILWSGWGLLSSSVGGLMDAGVDPHTDAQLRRVISEEATGALEIHDLRTRHSGQVT 262 Query: 239 HVELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 VE H+ V E +++ AH I + ++ V+ + + IHV+ Sbjct: 263 FVEFHLVVPSEMTVRDAHTICDRLEDAVQGVIAGANVTIHVE 304 >sp|P21559|P34_RICRI PROTEIN P34 >gi|97211|pir||S13095 P34 protein - Rickettsia rickettsii >gi|46397|emb|CAA39546.1| (X56068) P34 [Rickettsia rickettsii] Length = 301 Score = 105 bits (259), Expect = 7e-22 Identities = 63/272 (23%), Positives = 129/272 (47%), Gaps = 3/272 (1%) Query: 10 VSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFG 69 +S+ ++ +KL + S ++++ I S+ D +S + + ++ + +PPD H FG Sbjct: 16 LSVTTALIILSIKLYAWVVTDSQSILAALIDSMLDITSSFINLIALRFALQPPDHHHRFG 75 Query: 70 HSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRY 129 + + + L F A+ + S+ + + V + I + ++ Y Sbjct: 76 YEKLQDLTIFSQSIFFFASAFFVGFSSVKSLFEKTKPENISDGTTVMYVCIFLTIILVFY 135 Query: 130 ALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVG 189 V K+ ++I+ AD H+ +D+L+ ++V++ L WF D L G V++L++ Sbjct: 136 QTYVIKKTGSEIVKADKLHYFTDLLTNVIVIISINLSDY-FWFVDPLFGVVISLYIFHSS 194 Query: 190 VEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPE 249 + + L P + +KI + + G G+H+++ Y G K ++ H+E+ Sbjct: 195 YSLFKKAFKNLVDHELPEQDRQKIISIVNNHLGAKGMHEMKTRYAGQKAFIQCHLEMDGN 254 Query: 250 TSLKKAHDISEEVKRKV-ESLPEVSEAFIHVD 280 SL AH IS+E+ ++ + PE +E IH D Sbjct: 255 MSLYNAHKISDEIAFEILQEFPE-AEIIIHQD 285 >pir||H70941 hypothetical protein Rv2025c - Mycobacterium tuberculosis (strain H37RV) >gi|2896762|emb|CAA17239.1| (AL021899) hypothetical protein Rv2025c [Mycobacterium tuberculosis] Length = 332 Score = 105 bits (259), Expect = 7e-22 Identities = 63/275 (22%), Positives = 135/275 (48%), Gaps = 2/275 (0%) Query: 5 LKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDE 64 ++ + +S++ + ++++V+ + + S+AL +D IH+ +D +T+V ++ L KP Sbjct: 41 IRTVKISLLVLGLTALIQIVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR 100 Query: 65 SHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKE 124 + +G R E L F+ ++ + A +++ R++ + I + + L+ + E Sbjct: 101 RYTYGFGRVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFIGNE 160 Query: 125 LMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALF 184 + Y + VG R+ + +IAD H R+D +++ VL G LG D + G ++ Sbjct: 161 WVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCSAGGVALGFPLADPIVGLLITAA 220 Query: 185 VGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHI 244 + V + L P V E+ + GV V +R ++G +LH + + Sbjct: 221 ILAVLRTAARDVFRRLLDGVDPAMV-DAAEQALAARPGVQAVRSVRMRWIGHRLHADAEL 279 Query: 245 EVSPETSLKKAHDISEEVKRKV-ESLPEVSEAFIH 278 +V P L +AH I+ + + ++ ++P+++ A IH Sbjct: 280 DVDPALDLAQAHRIAHDAEHELTHTVPKLTTALIH 314 >sp|P32159|YIIP_ECOLI HYPOTHETICAL 32.9 KD PROTEIN IN CPXA-PFKA INTERGENIC REGION >gi|541122|pir||S40858 hypothetical 32.9K protein (cpxA-pfkA intergenic region) - Escherichia coli >gi|305018|gb|AAB03047.1| (L19201) similar to Rickettsia rickettsii protein P34 [Escherichia coli] >gi|1790349|gb|AAC76897.1| (AE000466) putative transport system permease protein [Escherichia coli K12] Length = 300 Score = 104 bits (258), Expect = 9e-22 Identities = 65/265 (24%), Positives = 131/265 (48%) Query: 16 TVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEP 75 ++L ++K+ + S+++++ + SL D S+ + V+ S +P D++H FGH + E Sbjct: 21 SLLLLIKIFAWWYTGSVSILAALVDSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAES 80 Query: 76 LFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGK 135 L A + A + + ++S + VIV +++++ ++ + V + Sbjct: 81 LAALAQSMFISGSALFLFLTGIQHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVR 140 Query: 136 RLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEILLE 195 R ++ + AD H++SDV+ +L+ GL G DAL + +++ + + E Sbjct: 141 RTQSQAVRADMLHYQSDVMMNGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYE 200 Query: 196 NVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPETSLKKA 255 V L RA P E ++I ++ S GV G HDLR G +++H+E+ L +A Sbjct: 201 AVQSLLDRALPDEERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQA 260 Query: 256 HDISEEVKRKVESLPEVSEAFIHVD 280 H ++++V++ + S+ IH D Sbjct: 261 HMVADQVEQAILRRFPGSDVIIHQD 285 >dbj|BAA99362.1| (AP002526) ESTs AU032649(S13048),D47505(S13048) correspond to a region of the predicted gene.~Similar to Arabidopsis thaliana chromosome II BAC F12L6; unknown protein. (AC004218) [Oryza sativa] >gi|9558472|dbj|BAB03393.1| (AP002538) ESTs AU032649(S13048),D47505(S13048) correspond to a region of the predicted gene.~Similar to Arabidopsis thaliana chromosome II BAC F12L6; unknown protein. (AC004218) [Oryza sativa] Length = 391 Score = 104 bits (258), Expect = 9e-22 Identities = 74/288 (25%), Positives = 140/288 (47%), Gaps = 9/288 (3%) Query: 2 EEELKPLI--------VSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFV 53 EEEL+ + +S I N +L + K++ + +LS+A+I+ + SL D ++ + + Sbjct: 91 EEELRQMAKGERLAINLSNIINLILFIGKVLASVESLSMAVIASTLDSLLDLLSGFILWF 150 Query: 54 GVKLSKKPPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMV 113 KKP S+P G R +P+ ++ + +++ +S ++++ E Sbjct: 151 TAHAMKKPNKYSYPIGKRRMQPVGIIVFASVMGTLGFQVLIESGRQLITNEHQVFDHRKE 210 Query: 114 IVALLSILVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFG 173 + + S+ ++ + + + N+I+ A A H DV++ V LV L W+ Sbjct: 211 LWMIGSMSSVAVVKFFLMLYCRSFKNEIVRAYAQDHFFDVITNSVGLVSALLAVRYKWWM 270 Query: 174 DALAGFVVALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVA-RSVDGVLGVHDLRAH 232 D + ++A++ ++ENV L GR+ P E K+ + + + + +RA+ Sbjct: 271 DPVGAILIAVYTITTWARTVVENVGTLIGRSAPAEYLTKLTYLIWNHHEEIRHIDTVRAY 330 Query: 233 YVGTKLHVELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 GT VE+ I + + L AHDI E ++ K+E LPEV AF+HVD Sbjct: 331 TFGTHYFVEVDIVLPGDMPLSHAHDIGESLQEKLEQLPEVERAFVHVD 378 >gb|AAD34683.1|AC006341_11 (AC006341) >F3O9.11 [Arabidopsis thaliana] Length = 398 Score = 102 bits (253), Expect = 4e-21 Identities = 75/292 (25%), Positives = 140/292 (47%), Gaps = 17/292 (5%) Query: 2 EEELKPLI--------VSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFV 53 EEE+K L +S N VL V K+ + + S+A+I+ + SL D ++ + + Sbjct: 99 EEEMKKLAKSERLAVHISNATNLVLFVAKVYASMESRSMAVIASTLDSLLDLLSGFILWF 158 Query: 54 GVKLSKKPPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPT-- 111 +KP +P G R +P+ ++ + ++ +S +++++ I + T Sbjct: 159 TANAMRKPNQFHYPIGKRRMQPVGIIVFASVMATLGLQVLLESGRQLVAKSGIHMNSTEE 218 Query: 112 --MVIVALLSILVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLG 169 M+ + + +VK L+ Y + N+I+ A A H DV++ + L L Sbjct: 219 KWMIGIMVSVTIVKFLLMLYC----RGFQNEIVRAYAQDHLFDVVTNSIGLATAVLAVKF 274 Query: 170 IWFGDALAGFVVALFVGKVGVEILLENVNYLTGR-APPYEVCKKIEEVARSVDGVLGVHD 228 W+ D ++AL+ +LENV+ L GR APP + K + + + + Sbjct: 275 YWWIDPTGAILIALYTIATWARTVLENVHSLIGRSAPPDFLAKLTFLIWNHHEQIKHIDT 334 Query: 229 LRAHYVGTKLHVELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 +RA+ G+ VE+ I + + L++AH+I E ++ K+E L EV AF+H+D Sbjct: 335 VRAYTFGSHYFVEVDIVLPEDMRLQEAHNIGETLQEKLEQLAEVERAFVHID 386 >pir||T00555 hypothetical protein F12L6.11 - Arabidopsis thaliana >gi|3355474|gb|AAC27836.1| (AC004218) unknown protein [Arabidopsis thaliana] Length = 394 Score = 102 bits (251), Expect = 6e-21 Identities = 77/285 (27%), Positives = 140/285 (49%), Gaps = 10/285 (3%) Query: 2 EEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKP 61 + E + +S I N +L K+ + + S+A+I+ + SL D ++ + + + P Sbjct: 100 KSETLAIRISNIANMLLFAAKVYASVTSGSLAIIASTLDSLLDLLSGFILWFTAFSMQTP 159 Query: 62 PDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLS-RETIRLTP---TMVIVAL 117 +P G R +PL ++ + +I +SL MLS + LT + V+ + Sbjct: 160 NPYQYPIGKKRMQPLGILVFASVMATLGLQIILESLRTMLSSHKEFNLTKEQESWVVGIM 219 Query: 118 LSI-LVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDAL 176 LS+ LVK L+ Y S N+I+ A A H DV++ I+ L+ L ++ D + Sbjct: 220 LSVTLVKLLLVLYCRS----FTNEIVKAYAQDHFFDVITNIIGLIAVILANYIDYWIDPV 275 Query: 177 AGFVVALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVA-RSVDGVLGVHDLRAHYVG 235 ++AL+ + +LENVN L G++ E +K+ + + + +RA+ G Sbjct: 276 GAIILALYTIRTWSMTVLENVNSLVGKSARPEYLQKLTYLCWNHHKAIRHIDTVRAYTFG 335 Query: 236 TKLHVELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 + VE+ I + + L+ AHDI E ++ K+E L E+ AF+H+D Sbjct: 336 SHYFVEVDIVLPADMPLQVAHDIGESLQEKLELLEEIERAFVHLD 380 >gb|AAD30224.1|AC007202_6 (AC007202) EST gb|AA404917 comes from this gene. [Arabidopsis thaliana] Length = 434 Score = 102 bits (251), Expect = 6e-21 Identities = 77/292 (26%), Positives = 138/292 (46%), Gaps = 17/292 (5%) Query: 2 EEELKPLI--------VSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFV 53 EEELK L +S N VL V K+ + + S+A+I+ + SL D ++ + + Sbjct: 102 EEELKKLAKSERLAVHISNAANLVLFVAKVYASVESRSMAVIASTLDSLLDLLSGFILWF 161 Query: 54 GVKLSKKPPDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPT-- 111 + P + +P G R +P+ ++ + ++ +S ++S+ ++ T Sbjct: 162 TANAMRTPNNFRYPIGKRRMQPVGIIVFASVMATLGLQVILESTRLLVSKNGSHMSSTEE 221 Query: 112 --MVIVALLSILVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLG 169 M+ + + +VK L+ Y S N+I+ A A H DV++ V L L Sbjct: 222 KWMIGIMASATVVKFLLMLYCRS----FQNEIVRAYAQDHLFDVITNSVGLATAVLAVKF 277 Query: 170 IWFGDALAGFVVALFVGKVGVEILLENVNYLTGR-APPYEVCKKIEEVARSVDGVLGVHD 228 W+ D ++AL+ +LENV+ L GR APP + K + + + + Sbjct: 278 YWWIDPSGAILIALYTISTWARTVLENVHSLIGRSAPPDFLAKLTFLIWNHHEKIKHIDT 337 Query: 229 LRAHYVGTKLHVELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 +RA+ G+ VE+ I + + L +AH+I E ++ K+E L EV AF+H+D Sbjct: 338 VRAYTFGSHYFVEVDIVLPEDMRLHEAHNIGETLQEKLEQLSEVERAFVHID 389 >pir||C69612 cation-efflux system membrane protein czcD - Bacillus subtilis >gi|1934656|gb|AAB80907.1| (U93876) cation transport protein YrdO [Bacillus subtilis] >gi|2635110|emb|CAB14606.1| (Z99117) cation-efflux system membrane protein [Bacillus subtilis] Length = 311 Score = 94.4 bits (231), Expect = 1e-18 Identities = 63/264 (23%), Positives = 131/264 (48%), Gaps = 3/264 (1%) Query: 6 KPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDES 65 K L++S I T +++ + G S+AL+SD H LSD+++ +V + L++K + + Sbjct: 12 KVLLISFIMITGYMIIEAIGGFLTNSLALLSDAGHMLSDSISLMVALIAFTLAEKKANHN 71 Query: 66 HPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKEL 125 FG+ RFE L A G LI+++ I +++ R + + T M+ ++++ ++V L Sbjct: 72 KTFGYKRFEILAAVINGAALILISLYIIYEAIERFSNPPKV-ATTGMLTISIIGLVVNLL 130 Query: 126 MTRYALSVGKRLDNKIIIADAYHHRSDVLSTI-VVLVGFGLQRLGIWFGDALAGFVVALF 184 + +S G +N I H SD+L ++ +L + G + D LA +VA+ Sbjct: 131 VAWIMMSGGDTKNNLNIRGAYLHVISDMLGSVGAILAAILIIFFGWGWADPLASIIVAIL 190 Query: 185 VGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLH-VELH 243 V + G + ++++ L P I +G+ +HDL + + L+ + H Sbjct: 191 VLRSGYNVTKDSIHILMEGTPENIDVSDIIRTIEGTEGIQNIHDLHIWSITSGLNALSCH 250 Query: 244 IEVSPETSLKKAHDISEEVKRKVE 267 V + ++ ++ +I +++ ++E Sbjct: 251 AVVDDQLTISESENILRKIEHELE 274 >dbj|BAA19587.1| (D87026) membrane protein [Bacillus stearothermophilus] Length = 317 Score = 91.7 bits (224), Expect = 9e-18 Identities = 69/279 (24%), Positives = 130/279 (45%), Gaps = 7/279 (2%) Query: 6 KPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDES 65 K L ++++ VV+++ G+ + S+AL+SD H SD + + V + ++ +PP+ Sbjct: 22 KALWITLVLTVFFTVVEIIGGVLSNSLALLSDSAHMASDVLALGLSMVALYMATRPPNRR 81 Query: 66 HPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKEL 125 FG RFE + +F G L V+A I + + R L E I+ M+ +A + ++V Sbjct: 82 FTFGFLRFEIIASFLNGLTLAVIAVWILWEGIERFLHPEPIQFR-LMLGIAAIGLIVNLT 140 Query: 126 MTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIW-FGDALAGFVVALF 184 +T K DN + + +H D++S+I V++ L W D + V+A Sbjct: 141 LTIVLSRSTKEEDNLNVQSALWHFIGDLISSIGVIISALLIYFTGWTIFDPIISLVIAAI 200 Query: 185 VGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGT-----KLH 239 + G +I+ E+ L P ++I R+++GV VHD+ + T H Sbjct: 201 IFTGGAKIMRESYLILMEAVPDEFDLEQIRADIRNIEGVEDVHDMHLWAISTDHYSLSAH 260 Query: 240 VELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIH 278 V ++ + P + +++ +E S +V A +H Sbjct: 261 VFVNEHIQPLCVILAVNEMLKEKYGIEHSTIQVEHAILH 299 >gi|11499720 conserved hypothetical transmembrane protein [Archaeoglobus fulgidus] >gi|7483267|pir||A69517 conserved hypothetical transmembrane protein AF2137 - Archaeoglobus fulgidus >gi|2648388|gb|AAB89114.1| (AE000956) conserved hypothetical transmembrane protein [Archaeoglobus fulgidus] Length = 283 Score = 87.8 bits (214), Expect = 1e-16 Identities = 62/267 (23%), Positives = 124/267 (46%), Gaps = 18/267 (6%) Query: 21 VKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAFF 80 +KL + A+++D HS+ D ++ + + ++K D HPFGH + + Sbjct: 14 IKLYAYFLSGFTAILADAFHSVIDITMILILLLSERYAEKEADYQHPFGHEMARNVASLA 73 Query: 81 MGELLIV-VAYEIARDSLGRML------SRETIRLTPTMVIVALLSILVKELMTRYALSV 133 +G I + +E+ ++ L ++L S + L + ++ALL I R + Sbjct: 74 VGVGFITFMFFELMKEGLLKVLHPASGYSNVEVALGAEVAVLALLVIAALISARRSGIL- 132 Query: 134 GKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEIL 193 N+ ++ ++ + D LST+ +VG GL G D +A +A + ++ Sbjct: 133 -----NRTLLVESLN---DSLSTLAAIVGVGLVWAGYPIFDGIATIAIAFIIFYNSFRLV 184 Query: 194 LENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVG-TKLHVELHIEVSPETSL 252 +N L G +P + + +E+ ++ V GVHD+ Y G +H++LH+ V ++ Sbjct: 185 RDNARLLIGMSPSEDFYRSVEDACLEIERVKGVHDMVGVYTGENSVHLDLHVTVDGAMTI 244 Query: 253 KKAHDISEEVKRKVESL-PEVSEAFIH 278 ++A +S E+ + + PEV +H Sbjct: 245 EEADKLSVEIAEAIMAKHPEVKHISVH 271 >gb|AAB53029.1| (U62055) CzcD [Bacillus subtilis] Length = 295 Score = 87.8 bits (214), Expect = 1e-16 Identities = 57/250 (22%), Positives = 124/250 (48%), Gaps = 3/250 (1%) Query: 20 VVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAF 79 +++ + G S+AL+SD H LSD+++ +V + L++K + + FG+ RFE L A Sbjct: 10 IIEAIGGFLTNSLALLSDAGHMLSDSISLMVALIAFTLAEKKANHNKTFGYKRFEILAAV 69 Query: 80 FMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGKRLDN 139 G LI+++ I +++ R + + T M+ ++++ ++V L+ +S G +N Sbjct: 70 INGAALILISLYIIYEAIERFSNPPKV-ATTGMLTISIIGLVVNLLVAWIMMSGGDTKNN 128 Query: 140 KIIIADAYHHRSDVLSTI-VVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEILLENVN 198 I H SD+L ++ +L + G + + LA +VA+ V + G + ++++ Sbjct: 129 LNIRGAYLHVISDMLGSVGAILAAILIIFFGWGWANPLASIIVAILVLRSGYNVTKDSIH 188 Query: 199 YLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLH-VELHIEVSPETSLKKAHD 257 L P I +G+ +HDL + + L+ + H V + ++ ++ + Sbjct: 189 ILMEGTPENIDVSDIIRTIEGTEGIQNIHDLHIWSITSGLNALSCHAVVDDQLTISESEN 248 Query: 258 ISEEVKRKVE 267 I +++ ++E Sbjct: 249 ILRKIEHELE 258 >pir||H71078 probable cation efflux system protein czcD - Pyrococcus horikoshii >gi|3257307|dbj|BAA29990.1| (AP000004) 295aa long hypothetical cation efflux system protein czcD [Pyrococcus horikoshii] Length = 295 Score = 87.4 bits (213), Expect = 2e-16 Identities = 68/265 (25%), Positives = 134/265 (49%), Gaps = 9/265 (3%) Query: 6 KPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDES 65 + +++S N + + +++ G+ + S+AL+SD +H+ SD++ + +K+ ++ +E Sbjct: 9 RKMMLSFSLNLGITLAEVIGGIISGSLALLSDSLHNFSDSMGIFASYFAIKIGERKKNEK 68 Query: 66 HPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKEL 125 FG+ R E L AF +L+ V+ + ++ R S E I+ M+ VAL+ + Sbjct: 69 FTFGYKRAEILVAFANSAVLVGVSLFLIFEAYKRFKSPEPIK-GSLMLFVALIGLFAN-- 125 Query: 126 MTRYALSVGKRLDNKIIIADAYHHR-SDVLSTI-VVLVGFGLQRLGIWFGDALAGFVVAL 183 + + + + I AY H SD LS+I VVL G + + +++ D L +++L Sbjct: 126 -LASVILLHEHAHESMNIRSAYLHLVSDSLSSIAVVLGGIAITKWNVFWIDPLITVLISL 184 Query: 184 FVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVG-TKLHVEL 242 ++ IL E++ L AP + +KI+E S+ V H A VG ++H E Sbjct: 185 YILHESYGILKESIEVLMEAAPNLDF-QKIKEEIESIPKVRNAHHFHAWRVGENEIHFEC 243 Query: 243 HIEVSPETSLKKAHDISEEVKRKVE 267 H+E + + L +A + + + K++ Sbjct: 244 HVE-TEDMLLSEAQKLIDAIADKLK 267 >pir||T31797 hypothetical protein R02F11.3 - Caenorhabditis elegans >gi|2315350|gb|AAB65899.1| (AF016439) R02F11.3 gene product [Caenorhabditis elegans] Length = 509 Score = 86.6 bits (211), Expect = 3e-16 Identities = 77/325 (23%), Positives = 137/325 (41%), Gaps = 58/325 (17%) Query: 10 VSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFG 69 +++ N +L + K+V + + S+++IS + S+ D + +V + ++ KK +P G Sbjct: 175 ITLAVNFLLMIAKVVASVLSGSMSIISSMVDSVVDITSGLVISLSERMIKKRDPYLYPRG 234 Query: 70 HSRFEPLFAFFM----------------------------GELLIVVAYEIARDSLGRML 101 +R EPL + G LLI + L L Sbjct: 235 RTRLEPLSLILISVIMGMASIQLIIASVRGIHDGIQFHLYGALLIFEPISVFELILSDWL 294 Query: 102 SRETIRL-------------------------TPTMVIVALLSILVKELMTRYALSVGKR 136 E I L T T V++ + ++LVK + + KR Sbjct: 295 ETELISLAVLSFGGNLQYIRPQRIGEEPKLNVTITSVVIMVSTVLVKLSLYLFC----KR 350 Query: 137 LDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEILLEN 196 + A HR+D +S V L+ L ++ D VV++++ V+ E+ Sbjct: 351 YKEPSVNVLAMDHRNDCISNTVALICAWLGTKYSYYFDPAGAIVVSMYILYTWVQTGREH 410 Query: 197 VNYLTGRAPPYEVCKKIEEVARSVDGVLG-VHDLRAHYVGTKLHVELHIEVSPETSLKKA 255 + L+G+ E +I +V D + + + ++ G+K VE+HI + LK++ Sbjct: 411 LAKLSGKTAEPEFINRIIKVCLDHDARISHIDTVYVYHFGSKFLVEVHIVLDENMILKES 470 Query: 256 HDISEEVKRKVESLPEVSEAFIHVD 280 HDISE ++ +ESLPEV AF+H D Sbjct: 471 HDISETLQSNIESLPEVERAFVHTD 495 >sp|P74068|YC63_SYNY3 HYPOTHETICAL 33.3 KD PROTEIN SLL1263 >gi|7429310|pir||S75583 hypothetical protein sll1263 - Synechocystis sp. (strain PCC 6803) >gi|1653229|dbj|BAA18144.1| (D90912) hypothetical protein [Synechocystis sp.] Length = 310 Score = 86.6 bits (211), Expect = 3e-16 Identities = 66/279 (23%), Positives = 127/279 (44%), Gaps = 5/279 (1%) Query: 6 KPLIVSIIGNTVLGVVKLVVGLFNL--SIALISDGIHSLSDTVTSVVGFVGVKLSKKPPD 63 +P V IG L + L +G + + S+ L+SD + S + +++V F + L+ P D Sbjct: 7 RPYAVLSIG-AALATMGLKLGAYAITGSVGLLSDALESTVNLASAIVAFWALSLAATPAD 65 Query: 64 ESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVK 123 HPFGHS+ E + G + V A I ++ R+LS + + +A+ + + Sbjct: 66 SEHPFGHSKAEYFSSGLEGAFIFVAALGIGYSAVERLLSPRPLDQNALGIALAIAATALN 125 Query: 124 ELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIW-FGDALAGFVVA 182 + GKRL++ + AD+ H +DV +++ V+V L + W + D L V Sbjct: 126 GTVAWILWRAGKRLNSIALRADSQHLMTDVWTSVGVVVAVALIFVTGWEWLDPLIALGVG 185 Query: 183 LFVGKVGVEILLENVNYLTGRA-PPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVE 241 V G +L E ++ L ++ PP ++ D + H L+ G++ + Sbjct: 186 FNVLWTGTHLLRETISSLMDQSLPPAQLQAITSCFLPYEDQGVRFHLLQTRQAGSQSFIS 245 Query: 242 LHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 H+ V ++++ HD+ E ++ + S H++ Sbjct: 246 FHVLVPGHWTVQRGHDLCEAIETAIAERITGSRVTTHLE 284 >pir||T40838 probable transporter - fission yeast (Schizosaccharomyces pombe) >gi|3130046|emb|CAA18991.1| (AL023518) putative transporter [Schizosaccharomyces pombe] Length = 397 Score = 86.2 bits (210), Expect = 4e-16 Identities = 75/303 (24%), Positives = 143/303 (46%), Gaps = 39/303 (12%) Query: 4 ELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPD 63 ELK + + N L K + G+ S L++D H L DT++ +V +K+ K P Sbjct: 73 ELKLAWLGLYSNIGLAAAKGIGGVALQSSILVADAAHQLGDTLSDLVTLATLKICSKKPT 132 Query: 64 ESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLS-------------------RE 104 + +P G ++E + F + LL+ V+ IA SL R+ + + Sbjct: 133 QKYPAGFGKWETIGTFTVSGLLVAVSVGIAHSSLSRLYTILFPYAGSEHTHIGHSHNPSQ 192 Query: 105 TIRLTPTMVIVALL-SILVKELMTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLVGF 163 + P M + + S+++KE + R +V ++ D+ I++A+A+HHR+D L+ +V L+ Sbjct: 193 LLFEHPFMALGLIFGSVVLKEWLFRKTRTVAQKTDSNILLANAWHHRADALTGMVSLLAL 252 Query: 164 -GLQRLGIWFGDALAGFVVALFVGKVGVEILLENVNYLTGRAPPYEV-------CKKIEE 215 G L + D G +V++ V G + L RAP E+ K E+ Sbjct: 253 SGTYFLNAPWLDPFFGCLVSIVVFSAGFNSSKKAFLQLLDRAPSEELRIAVTDALLKGEK 312 Query: 216 VARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPETSLKKAHDISEEVKRKV-ESLPEVSE 274 + + +LG AH +HV I V P + +++ +++++V++ V +++P +S Sbjct: 313 LPYKIVTILG----NAH----AMHV--IISVPPSFTSQQSSELAQKVEKTVLDAIPALSS 362 Query: 275 AFI 277 + Sbjct: 363 CIV 365 >sp|P13512|CZCD_ALCEU COBALT-ZINC-CADMIUM RESISTANCE PROTEIN CZCD (CATION EFFLUX SYSTEM PROTEIN CZCD) >gi|1403126|emb|CAA67085.1| (X98451) no histidine kinase, member of cation-diffusion-facilitator (CDF) family [Ralstonia sp. CH34] Length = 316 Score = 84.3 bits (205), Expect = 2e-15 Identities = 70/264 (26%), Positives = 129/264 (48%), Gaps = 7/264 (2%) Query: 20 VVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAF 79 + ++V G+ S+ALISD H L+DTV + + ++K+P D+ FG+ RFE L A Sbjct: 29 IAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPADKKRTFGYYRFEILAAA 88 Query: 80 FMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGKRLDN 139 F LL VA I ++ R+ S I T M +VA+L +++ L++ LS G+ + Sbjct: 89 FNALLLFGVAIYILYEAYLRLKSPPQIEST-GMFVVAVLGLII-NLISMRMLSSGQ--SS 144 Query: 140 KIIIADAY-HHRSDVLSTIVVLVGFGLQRLGIW-FGDALAGFVVALFVGKVGVEILLENV 197 + + AY SD+L ++ V+ G + R W + D+ ++ L+V +L ++ Sbjct: 145 SLNVKGAYLEVWSDLLGSVGVIAGAIIIRFTGWAWVDSAIAVLIGLWVLPRTWILLKSSL 204 Query: 198 NYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPETSLKKAHD 257 N L P ++E+ + GV HDL + T L + V +T++ + Sbjct: 205 NVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHI-WALTSGKASLTVHVVNDTAVNPEME 263 Query: 258 ISEEVKRKVESLPEVSEAFIHVDI 281 + E+K+ + +++ I ++ Sbjct: 264 VLPELKQMLADKFDITHVTIQFEL 287 >sp|P94178|CZCD_ALCSP CATION EFFLUX SYSTEM PROTEIN CZCD >gi|2120970|pir||JC4701 cadmium, zinc, cobalt divalent cation resistant determinant D - Alcaligenes sp >gi|1785481|dbj|BAA11062.1| (D67044) CzcD [Alcaligenes sp.] Length = 316 Score = 84.3 bits (205), Expect = 2e-15 Identities = 70/264 (26%), Positives = 129/264 (48%), Gaps = 7/264 (2%) Query: 20 VVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAF 79 + ++V G+ S+ALISD H L+DTV + + ++K+P D+ FG+ RFE L A Sbjct: 29 IAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPADKKRTFGYYRFEILAAA 88 Query: 80 FMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGKRLDN 139 F LL VA I ++ R+ S I T M +VA+L +++ L++ LS G+ + Sbjct: 89 FNALLLFGVAIYILYEAYLRLKSPPQIEST-GMFVVAVLGLII-NLISMRMLSSGQ--SS 144 Query: 140 KIIIADAY-HHRSDVLSTIVVLVGFGLQRLGIW-FGDALAGFVVALFVGKVGVEILLENV 197 + + AY SD+L ++ V+ G + R W + D+ ++ L+V +L ++ Sbjct: 145 SLNVKGAYLEVWSDLLGSVGVIAGAIIIRFTGWAWVDSAIAVLIGLWVLPRTWFLLKSSL 204 Query: 198 NYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSPETSLKKAHD 257 N L P ++E+ + GV HDL + T L + V +T++ + Sbjct: 205 NVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHI-WALTSGKASLTVHVVNDTAVNPEME 263 Query: 258 ISEEVKRKVESLPEVSEAFIHVDI 281 + E+K+ + +++ I ++ Sbjct: 264 VLPELKQMLADKFDITHVTIQFEL 287 >sp|P75757|YBGR_ECOLI HYPOTHETICAL 34.7 KDA PROTEIN IN PNUC-AROG INTERGENIC REGION >gi|7429309|pir||H64810 ybgR protein - Escherichia coli >gi|1786966|gb|AAC73839.1| (AE000177) putative transport system permease protein [Escherichia coli K12] >gi|4062324|dbj|BAA35414.1| (D90714) Cation efflux system protein CzcD. [Escherichia coli] Length = 313 Score = 81.1 bits (197), Expect = 1e-14 Identities = 60/234 (25%), Positives = 112/234 (47%), Gaps = 10/234 (4%) Query: 20 VVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAF 79 +V++V G + S+AL++D H L+DT + + V+ S++PP H FG R L AF Sbjct: 33 LVEVVGGFLSGSLALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAF 92 Query: 80 FMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGKRLDN 139 L+V+ I +++ R + + M++ ++ L+ +++ + L G N Sbjct: 93 VNAIALVVITILIVWEAIERFRTPRPVE--GGMMMAIAVAGLLANILSFWLLHHGSEEKN 150 Query: 140 KIIIADAYHHRSDVLSTIVVLVGFGLQRLGIWFG----DALAGFVVALFVGKVGVEILLE 195 + A A H D+L ++ ++ + IW G D + +V+L V + +L + Sbjct: 151 LNVRAAALHVLGDLLGSVGAIIA---ALIIIWTGWTPADPILSILVSLLVLRSAWRLLKD 207 Query: 196 NVNYLTGRAP-PYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELHIEVSP 248 +VN L AP ++ + + R + V VH + VG K + LH++V P Sbjct: 208 SVNELLEGAPVSLDIAELKRRMCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIP 261 >pir||E70392 cation efflux system (czcD-like) - Aquifex aeolicus >gi|2983552|gb|AAC07126.1| (AE000721) cation efflux system (czcD-like) [Aquifex aeolicus] Length = 308 Score = 80.8 bits (196), Expect = 2e-14 Identities = 72/267 (26%), Positives = 130/267 (47%), Gaps = 13/267 (4%) Query: 2 EEELKPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKP 61 E+ LK L S + + ++ + GL S+AL+SD H L+D V+ + V L+ K Sbjct: 4 EKSLKVLAFSFLLIFLFAFIEFLGGLLTNSLALLSDAGHMLTDAVSLSIALVAQYLALKV 63 Query: 62 PDESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSIL 121 + +G R E L A G L+ + I +++ R + E ++ P M+ +A ++ Sbjct: 64 KTKRTTYGLYRLEVLAALVNGVFLLGLIGYIILEAIHRFENPEPVK--PQMIYIAFAGLI 121 Query: 122 VKELMTRYALSVGKRLDNKIIIADA-YHHRSDVLSTI-VVLVGFGLQRLGIWFGDALAGF 179 V L+ Y L K + I I A H +D L ++ ++ G + + D + Sbjct: 122 V-NLVVGYILL--KHSEENINIKSALLHVATDTLGSVAAIIAGIAIVFWKFYLADPILSV 178 Query: 180 VVALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYV--GTK 237 VAL + ++ E VN L AP + +++E+ ++ GV GVHDL + GT+ Sbjct: 179 AVALLILPSAYSVIKETVNVLLEVAPSHINTEELEKELLNLQGVKGVHDLHVWSITPGTE 238 Query: 238 LHVELHIEVSPETSLKKAHDISEEVKR 264 + + +H+ V +TS+ +DI +EV++ Sbjct: 239 V-LTVHVVVE-DTSI--CNDILKEVEK 261 >pir||T16470 hypothetical protein F56C9.3 - Caenorhabditis elegans >gi|488189|gb|AAB08712.1| (U00063) weakly similar to R. rickettsii protein P34 [Caenorhabditis elegans] Length = 435 Score = 77.6 bits (188), Expect = 1e-13 Identities = 62/294 (21%), Positives = 130/294 (44%), Gaps = 23/294 (7%) Query: 10 VSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFG 69 +++ N VL + K+ + S+++IS + S+ D + V + ++ +K +P G Sbjct: 128 ITLFVNLVLMLAKIFASYLSGSMSIISSMVDSVVDLTSGAVLSISSRMIRKRDPYQYPRG 187 Query: 70 HSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLT-PTMVIVALLSILVKELMTR 128 +R EPL + ++ + + ++ S+ R+ + P V ++I+ + + Sbjct: 188 RTRVEPLSLILISVIMGMASVQLIISSVRRIHDAAVYGIKDPINVSWPTIAIMGSTIAVK 247 Query: 129 YALSV--GKRLDNKIIIADAYHHRSDVLSTIVVLVGFGL-------------------QR 167 L + K N I + HR+D +S + L L ++ Sbjct: 248 LTLFIICQKYKSNSSIKVLSLDHRNDCISNSMALACAWLAFYYTVKDGDEKSGAVVFEKQ 307 Query: 168 LGIWFGDALAGFVVALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDG-VLGV 226 +++ D +V++++ + + L+G++ E+ +I D + + Sbjct: 308 FDLYYLDPAGAILVSVYILYTWIRTGYAHFVMLSGKSAHPELINRIVHQCIEHDPRITHI 367 Query: 227 HDLRAHYVGTKLHVELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVD 280 + ++ GTK VE+HI + SLK HDI+E ++ +ESLPE+ AF+H D Sbjct: 368 DTVYVYHYGTKFLVEVHIVLDQNMSLKVTHDIAESLQTGIESLPEIERAFVHCD 421 >pir||E81321 probable cation transport protein Cj1163c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968596|emb|CAB73417.1| (AL139077) putative cation transport protein [Campylobacter jejuni] Length = 316 Score = 76.9 bits (186), Expect = 3e-13 Identities = 63/263 (23%), Positives = 130/263 (48%), Gaps = 7/263 (2%) Query: 6 KPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDES 65 K L +S++ + +V+ + + + S+AL+SD +H SD + F+ + +K D Sbjct: 39 KILKISLLMTFSMMLVQFIYSILSNSLALLSDTLHMFSDVFALALSFLAIIAVEKWQDHQ 98 Query: 66 HPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKEL 125 FG+ R E L AF +I+ A I +++ + ++ + I TM+IVA+L LV + Sbjct: 99 KTFGYFRLEVLVAFINALTIILSALFIIYEAIEKFINPKEID-AKTMIIVAILGFLVNGI 157 Query: 126 MTRYALSVGKRLDNKIIIADAYHHRSDVLSTIVVLV-GFGLQRLGIWFGDALAGFVVALF 184 + G L+N + + H SD+L ++ V++ G + I + D + V+++ Sbjct: 158 -NALMMFKGANLENVNMKSAFLHMMSDLLGSLAVIIGGIVVYFSDIVYIDTILAIVLSIL 216 Query: 185 VGKVGVEILLENVNYLTGRAP-PYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHVELH 243 + + + +L ++ N L +P E +++ + SVD V+ +H L +H Sbjct: 217 LLRWAIILLKQSANVLLESSPVDIEKVRQVLLLNPSVDEVVDLH--ITQITNKMLVASMH 274 Query: 244 IEVSPETSLKKAHDISEEVKRKV 266 ++V +LK+ +S+++ K+ Sbjct: 275 LKVR-VCNLKEFEKLSQDLSHKL 296 >pir||C83595 probable cation efflux system protein PA0397 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946251|gb|AAG03786.1|AE004477_3 (AE004477) probable cation efflux system protein [Pseudomonas aeruginosa] Length = 299 Score = 76.9 bits (186), Expect = 3e-13 Identities = 67/264 (25%), Positives = 127/264 (47%), Gaps = 9/264 (3%) Query: 20 VVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAF 79 V ++V G+ S+ALISD H L+D V + + ++++P ++ +G+ RFE L A Sbjct: 29 VAEVVGGILTGSLALISDAAHMLTDAVALAIALAAINIARRPTNDRLTYGYHRFEILAAA 88 Query: 80 FMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVK-ELMTRYALSVGKRLD 138 F LL VA+ I + R+ I+ + M+++A+L +LV M A + G L+ Sbjct: 89 FNAFLLFGVAFYILYAAYERLNQPAEIQ-SVGMLVIAVLGLLVNLASMRLLAPAQGNSLN 147 Query: 139 NKIIIADAYHHRSDVLSTIVVLVGFGLQRLGIW-FGDALAGFVVALFVGKVGVEILLENV 197 K + + SD+L ++ V+V + R W + D+L ++ +V +L E++ Sbjct: 148 VKGAYLEVW---SDMLGSLGVIVAAIVIRFTGWAWVDSLVAVLIGFWVLPRTWILLRESL 204 Query: 198 NYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGT-KLHVELHIEVSPETSLKKAH 256 + L P ++ E + GV G+HDL + + K+ + H+ P +L A Sbjct: 205 HVLLEGVPKEIQLAELREALLGIPGVTGLHDLHVWSITSGKISLTSHLVYDP--ALVDAE 262 Query: 257 DISEEVKRKVESLPEVSEAFIHVD 280 + VK + E+ + + ++ Sbjct: 263 ALLGTVKALLHDRYEIEHSTLQLE 286 >pir||T46028 hypothetical protein T10K17.270 - Arabidopsis thaliana >gi|6729549|emb|CAB67634.1| (AL132977) putative protein [Arabidopsis thaliana] Length = 390 Score = 75.3 bits (182), Expect = 8e-13 Identities = 65/253 (25%), Positives = 115/253 (44%), Gaps = 18/253 (7%) Query: 31 SIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAFFMGELLIVVAY 90 SIA+ + + SL D + + + K +P G R +P+ ++ +A Sbjct: 134 SIAIAASTLDSLLDLMAGGILWFTHLSMKNVNIYKYPIGKLRVQPVGIIIFAAVMATLAE 193 Query: 91 EIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVG-KRLDNKIIIADAYHH 149 ++ +S E + ++ L SI++ + L + K N I+ A A H Sbjct: 194 QL--------ISNEPSEKMNHVQLIWLYSIMLSATAIKLVLWIYCKSSRNHIVRAYAKDH 245 Query: 150 RSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEILLENVNYLTGRAPPYEV 209 DV++ ++ LV L W+ D ++A++ ++EN APP EV Sbjct: 246 HFDVVTNVLGLVAAVLANAFYWWLDPTGAILLAIYTIVNWSGTVMENA------APP-EV 298 Query: 210 CKKIEEVA--RSVDGVLGVHDLRAHYVGTKLHVELHIEVSPETSLKKAHDISEEVKRKVE 267 +K+ + + D + V +RA+ G VE+ IE+ + LK+AH I E ++ K+E Sbjct: 299 LQKLTYLVMRQGGDNIKHVDTVRAYTFGVLYFVEVDIELPEDLPLKEAHAIGESLQIKLE 358 Query: 268 SLPEVSEAFIHVD 280 LPEV AF+H+D Sbjct: 359 ELPEVERAFVHLD 371 >pir||T16640 hypothetical protein PDB1.1 - Caenorhabditis elegans >gi|1072207|gb|AAA81718.1| (U40944) similar to C. elegans protein F56C9.3 [Caenorhabditis elegans] Length = 238 Score = 74.5 bits (180), Expect = 1e-12 Identities = 59/237 (24%), Positives = 110/237 (45%), Gaps = 27/237 (11%) Query: 64 ESHPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETI-----RLTPTMVIVALL 118 E +P G + EPL +G +++ + + L R T+ +L P + + L+ Sbjct: 4 EQYPVGMRKLEPLTVVIVGMIMLFANFIV--------LERATVQTIEDKLDPRVDLTTLI 55 Query: 119 SILVKELMTRYALSVGKRLDNK---IIIA---------DAYHHRSDVLSTIVVLVGFGLQ 166 +L T++ L + R+ +++A D+ R+D L+ IV L+G + Sbjct: 56 -VLCTGTATKFCLFMICRVRKSAACLVLAIDQVNFSDSDSAFTRNDCLTNIVALLGAWIG 114 Query: 167 RLGIWFGDALAGFVVALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGV 226 + + D L F+V+ F+ + E++ YL GR E +I ++ + D + Sbjct: 115 QNWWKYADPLGAFMVSGFIIVTWFLTIREHIPYLIGRRADQEFINRITNISINHDQRIKA 174 Query: 227 HD-LRAHYVGTKLHVELHIEVSPETSLKKAHDISEEVKRKVESLPEVSEAFIHVDIR 282 D + ++ G K VE+H L+ AHD++E ++ K+E LP V AF+H D + Sbjct: 175 LDTVHVYHFGEKFLVEVHAVFDEPAPLQMAHDVAESLQVKLEKLPFVERAFVHCDYK 231 >pir||T44365 cation-efflux system membrane protein homolog [imported] - Staphylococcus aureus >gi|4126672|dbj|BAA36686.1| (AB016431) czcD [Staphylococcus aureus] Length = 325 Score = 74.5 bits (180), Expect = 1e-12 Identities = 56/260 (21%), Positives = 116/260 (44%), Gaps = 3/260 (1%) Query: 6 KPLIVSIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDES 65 K L +S + + ++++ GL S+AL+SDGIH SDT + V V ++K + Sbjct: 20 KVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTT 79 Query: 66 HPFGHSRFEPLFAFFMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKEL 125 FG+ RFE L A F G L V++ I +++ R ++ + M+I++++ ++V + Sbjct: 80 KTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQ-SKEMLIISIIGLIVNIV 138 Query: 126 MTRYALSVGKRLDNKIIIADAYHHRSDVLSTI-VVLVGFGLQRLGIWFGDALAGFVVALF 184 + + G N + H D+L ++ + + G D +A +V++ Sbjct: 139 VAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVI 198 Query: 185 VGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLH-VELH 243 + K I ++N L P ++ + + VHD + ++ + H Sbjct: 199 ILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCH 258 Query: 244 IEVSPETSLKKAHDISEEVK 263 + V ++K+ + E ++ Sbjct: 259 VVVDHTLTMKECELLLENIE 278 >gb|AAF26917.1|AF210843_14 (AF210843) putative transport protein [Sorangium cellulosum] Length = 305 Score = 74.1 bits (179), Expect = 2e-12 Identities = 72/296 (24%), Positives = 126/296 (42%), Gaps = 21/296 (7%) Query: 1 MEEELKPLIV-SIIGNTVLGVVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSK 59 ME+E + I +I N + VK + S A++S+G+HSL DT ++ +G S Sbjct: 1 MEKESRIAIYGAIAANVAIAAVKFIAAAVTGSSAMLSEGVHSLVDTADGLLLLLGKHRSA 60 Query: 60 KPPDESHPFGHSRFEPLFAFFMGELLIVVAYEIA-RDSLGRMLSRETIRLTPTMVIVALL 118 +PPD HPFGH + + + ++ ++ + + +L I PT V L Sbjct: 61 RPPDAEHPFGHGKELYFWTLIVAIMIFAAGGGVSIYEGILHLLHPRQIE-DPTWNYVVLG 119 Query: 119 SILVKELMTRYALSVG--KRLDNKIIIADAYHHRSDVLSTIVV-----LVGFGLQRLGIW 171 + V E T +S+ K+ D + +A + TIV+ L G + LG+W Sbjct: 120 AAAVFE-GTSLIISIHEFKKKDGQGYLAAMRSSKDPTTFTIVLEDSAALAGLTIAFLGVW 178 Query: 172 FG--------DALAGFVVALFVGKVGVEILLENVNYLTGRAPPYEVCKKIEEVARSVDGV 223 G D A + L + V V + ++ L G + E+ I +A + GV Sbjct: 179 LGHRLGNPYLDGAASIGIGLVLAAVAVFLASQSRGLLVGESADRELLAAIRALASADPGV 238 Query: 224 LGV-HDLRAHYVGTKLHVELHIEVSPETSLKKAHDISEEVKRKVES-LPEVSEAFI 277 V L H+ ++ V L IE + + E ++ ++ S P+V ++ Sbjct: 239 SAVGRPLTMHFGPHEVLVVLRIEFDAALTASGVAEAIERIETRIRSERPDVKHIYV 294 >pir||G82752 cobalt-zinc-cadmium resistance protein XF0866 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9105776|gb|AAF83676.1|AE003926_5 (AE003926) cobalt-zinc-cadmium resistance protein [Xylella fastidiosa] Length = 321 Score = 74.1 bits (179), Expect = 2e-12 Identities = 55/221 (24%), Positives = 109/221 (48%), Gaps = 6/221 (2%) Query: 20 VVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAF 79 V +++ + S+AL+SD +H +D ++ V V+LS++PPD +G++R E A Sbjct: 51 VAEIIGAVLTRSLALLSDAVHMATDVFALMIALVAVRLSRRPPDVRRTYGYARLEAFGAL 110 Query: 80 FMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYA-LSVGKRLD 138 G LL V I +++ R+ + + I ++ M+++A+L +++ ++ R G+ L Sbjct: 111 VNGVLLFGVGGYILWEAVQRLRAPQEI-VSSGMLVIAVLGLVINLIVMRLLHAGRGENLS 169 Query: 139 NKIIIADAYHHRSDVLSTIVVLV-GFGLQRLGIWFGDALAGFVVALFVGKVGVEILLENV 197 K + + SD+L ++ V+V + G ++ D + ++ L+V +L E V Sbjct: 170 MKGAYLEVW---SDMLGSVAVIVAAIVIYVTGWYWVDPVLAVLIGLWVLPRTWVLLGEAV 226 Query: 198 NYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKL 238 N L P I + GV VHD+ +G+++ Sbjct: 227 NVLLEGVPKGFELLPIRDALSHHPGVANVHDVHLWALGSRM 267 >pir||A75437 cation efflux system protein - Deinococcus radiodurans (strain R1) >gi|6458837|gb|AAF10676.1|AE001960_4 (AE001960) cation efflux system protein [Deinococcus radiodurans] Length = 325 Score = 73.7 bits (178), Expect = 2e-12 Identities = 61/244 (25%), Positives = 114/244 (46%), Gaps = 9/244 (3%) Query: 20 VVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAF 79 V+++ L + S+AL+SD H L+D + +++ ++P D FG+ R E L A Sbjct: 61 VLEVAYALSSRSLALLSDAGHMLTDVAALALALFAIRMGRRPADRQRTFGYRRTEVLAAA 120 Query: 80 FMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGKRLDN 139 L + I +++ R R+ + + T ++V ++ LV L++ L+ G+ L+ Sbjct: 121 LNAGALFAIGLYILWEAVQRF--RQPVEVQTTSMLVVAVAGLVVNLLSARLLAGGEGLNL 178 Query: 140 KIIIADAYHHRSDVLSTIVVLVGFGLQRLGIW-FGDALAGFVVALFVGKVGVEILLENVN 198 + + D+L ++ V+ G L RL W + D L G + L+V +L +VN Sbjct: 179 RAAYLEVL---GDLLGSVAVIAGALLIRLTGWSWVDPLLGAGIGLWVLPRTWSLLKTSVN 235 Query: 199 YLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYV-GTKLHVELHI--EVSPETSLKKA 255 L P + R++ GV VHDL V G +++ H+ + +P L Sbjct: 236 VLLEGVPEGLDLDALRAELRALPGVQDVHDLHVWSVTGGVVNLTAHLVSDRAPAELLPAV 295 Query: 256 HDIS 259 H+++ Sbjct: 296 HEVA 299 >pir||D33830 cation efflux system membrane protein czcD - Alcaligenes eutrophus Length = 199 Score = 71.4 bits (172), Expect = 1e-11 Identities = 53/168 (31%), Positives = 90/168 (53%), Gaps = 6/168 (3%) Query: 20 VVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAF 79 + ++V G+ S+ALISD H L+DTV + + ++K+P D+ FG+ RFE L A Sbjct: 29 IAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPADKKRTFGYYRFEILAAA 88 Query: 80 FMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGKRLDN 139 F LL VA I ++ R+ S I T M +VA+L +++ L++ LS G+ + Sbjct: 89 FNALLLFGVAIYILYEAYLRLKSPPQIEST-GMFVVAVLGLII-NLISMRMLSSGQ--SS 144 Query: 140 KIIIADAY-HHRSDVLSTIVVLVGFGLQRLGIW-FGDALAGFVVALFV 185 + + AY SD+L ++ V+ G + R W + D+ ++ L+V Sbjct: 145 SLNVKGAYLEVWSDLLGSVGVIAGAIIIRFTGWAWVDSAIAVLIGLWV 192 >gb|AAC32485.1| (AF044951) transport protein [Staphylococcus aureus] Length = 326 Score = 69.5 bits (167), Expect = 4e-11 Identities = 52/245 (21%), Positives = 108/245 (43%), Gaps = 3/245 (1%) Query: 21 VKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAFF 80 ++++ GL S+AL+ DGIH SDT + V V ++K + FG+ RFE L A F Sbjct: 36 IEIIGGLLANSLALLRDGIHMSSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALF 95 Query: 81 MGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGKRLDNK 140 G L V++ I +++ R ++ + M+I++++ ++V ++ + G N Sbjct: 96 NGVTLFVISILIVFEAITRFFVPSEVQ-SKEMLIISIIGLIVNIVVAFFRFKGGDTSHNL 154 Query: 141 IIIADAYHHRSDVLSTI-VVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEILLENVNY 199 + H D+L ++ + + G D +A +V++ + K I ++N Sbjct: 155 NMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINI 214 Query: 200 LTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLH-VELHIEVSPETSLKKAHDI 258 L P ++ + VHD + ++ + H+ V ++K+ + Sbjct: 215 LMEGTPSDVDIDEVITTITKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELL 274 Query: 259 SEEVK 263 E ++ Sbjct: 275 LENIE 279 >pir||T35276 probable efflux protein - Streptomyces coelicolor >gi|4584498|emb|CAB40701.1| (AL049587) putative efflux protein [Streptomyces coelicolor A3(2)] Length = 312 Score = 68.3 bits (164), Expect = 1e-10 Identities = 61/245 (24%), Positives = 112/245 (44%), Gaps = 15/245 (6%) Query: 20 VVKLVVGLFNLSIALISDGIHSLSDTVTSVVGFVGVKLSKKPPDESHPFGHSRFEPLFAF 79 VV++V GL S+ALI+D H +D + + + V + +PP + FG++R E L A Sbjct: 39 VVEIVGGLVADSLALIADAAHMATDALGLGMALLAVHFASRPPSDRRTFGYARAEILAAL 98 Query: 80 FMGELLIVVAYEIARDSLGRMLSRETIRLTPTMVIVALLSILVKELMTRYALSVGKRLDN 139 LL+ V + +++ R ++ PT+V A+ LV +++ L G++ Sbjct: 99 ANCLLLLGVGGYVLYEAIDRFVTPADTAAGPTVVFGAI--GLVANMVSLSLLMRGQKESL 156 Query: 140 KI------IIADAYHHRSDVLSTIVVLVGFGLQRLGIWFGDALAGFVVALFVGKVGVEIL 193 + + ADA + ++S +V+L G D +A ++ L + + +L Sbjct: 157 NVRGAFLEVAADALGSLAVIVSALVILA------TGWQPADPIASLLIGLMIVPRTLRLL 210 Query: 194 LENVNYLTGRAPPYEVCKKIEEVARSVDGVLGVHDLRAHYVGTKLHV-ELHIEVSPETSL 252 E ++ L AP ++ ++DGV VHDL A + + + V H+ V E Sbjct: 211 RETLDVLLEAAPKGVDIAEVRAHILALDGVEDVHDLHAWTITSGMPVLSAHVVVDGEALS 270 Query: 253 KKAHD 257 H+ Sbjct: 271 AIGHE 275 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.322 0.141 0.395 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 97580081 Number of Sequences: 2977 Number of extensions: 3792255 Number of successful extensions: 10773 Number of sequences better than 1.0e-10: 52 Number of HSP's better than 0.0 without gapping: 19 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 10667 Number of HSP's gapped (non-prelim): 57 length of query: 283 length of database: 189,106,746 effective HSP length: 56 effective length of query: 227 effective length of database: 155,591,474 effective search space: 35319264598 effective search space used: 35319264598 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.9 bits) S2: 164 (68.3 bits)